Miracle-dz/UniFAR-FTUs huggingface dataset:
Incremental Density-Based Clustering on Multicore Processors

The density-based clustering algorithm is a fundamental data clustering technique with many real-world applications. However, when the database is frequently changed, how to effectively update clustering results rather than reclustering from scratch remains a challenging task. In this work, we introduce IncAnyDBC, a unique parallel incremental data clustering approach to deal with this problem. First, IncAnyDBC can process changes in bulks rather than batches like state-of-the-art methods for reducing update overheads. Second, it keeps an underlying cluster structure called the object node graph during the clustering process and uses it as a basis for incrementally updating clusters wrt. inserted or deleted objects in the database by propagating changes around affected nodes only. In additional, IncAnyDBC actively and iteratively examines the graph and chooses only a small set of most meaningful objects to produce exact clustering results of DBSCAN or to approximate results under arbitrary time constraints. This makes it more efficient than other existing methods. Third, by processing objects in blocks, IncAnyDBC can be efficiently parallelized on multicore CPUs, thus creating a work-efficient method. It runs much faster than existing techniques using one thread while still scaling well with multiple threads. Experiments are conducted on various large real datasets for demonstrating the performance of IncAnyDBC.
Development and Validation of the Drama Triangle Scale: Are You a Victim, Rescuer, or Persecutor?

The drama triangle is a theoretical framework to describe and understand the roles (Victim, Rescuer, and Persecutor) that people assume and perpetuate in interpersonal relationships, especially in contexts of “drama” or conflict. The Drama Triangle scale was developed, validated, and psychometrically scrutinized across three independent samples of adults. In Study 1 (N = 326), the initial pool of items was generated based on reviewing the literature. Exploratory factor analysis supported the three-factor structure of Victim (damsel in distress), Rescuer (hero), and Persecutor (villain) roles. In Study 2 (N = 342), confirmatory factor analysis (CFA) produced satisfactory fit indices. In Study 3 (N = 301), another CFA successfully cross-validated the final set of items. Furthermore, tests of convergent, discriminant, and criterion validities evaluated this scale against previously validated external measures of attachment styles, anxiety, stress, depression, positive emotions, and negative emotions. The drama triangle subscales tended to be associated with non-secure attachment styles and higher anxiety, stress, depression, and negative emotions, but results varied depending on the specific drama subscale. The Victim subscale was most strongly connected with undesirable outcomes, supporting the theoretical premise that Victims receive blame from Persecutors and help from Rescuers. This measurement instrument helps to conceptualize, measure, and understand the drama roles of Victim, Rescuer, and Persecutor that people enact in interpersonal relationships. The scale offers theoretical and applied implications for administration in future research on interpersonal conflict, aggression, violence, and other domains.
An Acylsucrose-Producing Tomato Line Derived from the Wild Species Solanum pimpinellifolium Decreases Fitness of the Whitefly Trialeurodes vaporariorum

Simple Summary The greenhouse whitefly, Trialeurodes vaporariorum is an insect pest of many plant crops including tomato and is especially harmful because it is a vector for a number of plant viral diseases. In this paper, an improved tomato line bred to produce glandular trichomes that exudate the deterrent compounds acylsucroses, which was introgressed from a wild tomato species, was demonstrated to decrease fitness of the insect and showed as a means for controlling the pests and, indirectly, could be an aid to reduce virus transmission to tomato plants. Abstract A combination of biological control and host plant resistance would be desirable for optimally controlling the greenhouse whitefly, Trialeurodes vaporariorum in tomato crops. Whitefly settlement preference, oviposition, and survivorship were evaluated on ABL 10-4 and ‘Moneymaker’, two nearly-isogenic tomato lines with, and without, whitefly-resistance traits based on type IV leaf glandular trichomes derived from the tomato wild species Solanum pimpinellifolium, respectively. Significantly reduced preference of T. vaporariorum adult whiteflies for ABL 10-4 leaves was observed. Moreover, T. vaporariorum altered its abaxial–adaxial settling performance on leaves of ABL 10-4 plants. A significantly lower tendency to settle on abaxial leaf surface was observed in ABL 10-4 compared to Moneymaker plants. Furthermore, T. vaporariorum deposited fewer eggs and exhibited a significantly reduced egg to adult survivorship in ABL 10-4 than in Moneymaker plants. Therefore, reduced fitness and distorted performance were observed for T. vaporariorum on ABL 10-4 tomato plants supporting that type IV leaf glandular trichomes might protect them from this pest and, indirectly, from the viruses it transmits.
Genome-Wide Identification, Characterization and Expression Analysis of TCP Transcription Factors in Petunia

The plant-specific TCP transcription factors are well-characterized in both monocots and dicots, which have been implicated in multiple aspects of plant biological processes such as leaf morphogenesis and senescence, lateral branching, flower development and hormone crosstalk. However, no systematic analysis of the petunia TCP gene family has been described. In this work, a total of 66 petunia TCP genes (32 PaTCP genes in P. axillaris and 34 PiTCP genes in P. inflata) were identified. Subsequently, a systematic analysis of 32 PaTCP genes was performed. The phylogenetic analysis combined with structural analysis clearly distinguished the 32 PaTCP proteins into two classes—class Ι and class Ⅱ. Class Ⅱ was further divided into two subclades, namely, the CIN-TCP subclade and the CYC/TB1 subclade. Plenty of cis-acting elements responsible for plant growth and development, phytohormone and/or stress responses were identified in the promoter of PaTCPs. Distinct spatial expression patterns were determined among PaTCP genes, suggesting that these genes may have diverse regulatory roles in plant growth development. Furthermore, differential temporal expression patterns were observed between the large- and small-flowered petunia lines for most PaTCP genes, suggesting that these genes are likely to be related to petal development and/or petal size in petunia. The spatiotemporal expression profiles and promoter analysis of PaTCPs indicated that these genes play important roles in petunia diverse developmental processes that may work via multiple hormone pathways. Moreover, three PaTCP-YFP fusion proteins were detected in nuclei through subcellular localization analysis. This is the first comprehensive analysis of the petunia TCP gene family on a genome-wide scale, which provides the basis for further functional characterization of this gene family in petunia.
Nonverbal communication in selfies posted on Instagram: Another look at the effect of gender on vertical camera angle

Background Selfies are a novel social phenomenon that is gradually beginning to receive attention within the cognitive sciences. Several studies have documented biases that may be related to nonverbal communicative intentions. For instance, in selfies posted on the dating platform Tinder males but not females prefer camera views from below (Sedgewick, Flath & Elias, 2017). We re-examined this study to assess whether this bias is confined to dating selection contexts and to compare variability between individuals and between genders. Methods Three raters evaluated vertical camera position in 2000 selfies– 1000 by males and 1000 by females—posted in Instagram. Results We found that the choices of camera angle do seem to vary depending on the context under which the selfies were uploaded. On Tinder, females appear more likely to choose neutral, frontal presentations than they do on Instagram, whereas males on Tinder appear more likely to opt for camera angles from below than on Instagram. Conclusions This result confirms that the composition of selfies is constrained by factors affecting nonverbal communicative intentions.
Effects of Bacillus amyloliquefaciens and Bacillus pumilus on Rumen and Intestine Morphology and Microbiota in Weanling Jintang Black Goat

Simple Summary Selecting Bacillus amyloliquefaciens and Bacillus pumilus in the present work, antibiotic substitutes were found for weaned black goat health and growth. This study indicated that Bacillus amyloliquefaciens fsznc-06 and Bacillus pumilus fsznc-09 improved the development of rumen and small intestine in weanling Jintang black goats. They also regulated microbial communities by increasing the richness of beneficial bacteria, but decreasing that of pathogenic bacteria in rumen and caecum for nutrient metabolism and promoting healthy conditions. Abstract The importance of Bacillus as feed additives in animals’ production is well recognized. Bacillus amyloliquefaciens and Bacillus pumilus are involved in promoting animal growth performance and immunological indicators. However, their precise roles in the modulation of microbiota and immune response in goat rumen and intestines have not been investigated. The aim of the current work was to evaluate the impacts of Bacillus amyloliquefaciens fsznc-06 and Bacillus pumilus fsznc-09 in the development of rumen and small intestinal and microbial communities in rumen and caecum of weanling Jintang black goats. Morphological alterations of rumen and small intestine (duodenum, jejunum, and ileum) were evaluated by histochemical staining, and ruminal contents and cecal feces were analyzed by 16S rRNA sequencing in an Illumina NovaSeq platform. Morphological analysis showed that feeding weanling goats with Bacillus amyloliquefaciens fsznc-06 or Bacillus pumilus fsznc-09 enhanced ruminal papilla and small intestinal villus growth. In addition, 16S rRNA sequencing analysis indicated that microbial richness and diversity (Shannon, Simpson, Chao1, and ACE) and the relative richness of multiple or potential beneficial bacteria were higher in weaned black goats fed on Bacillus amyloliquefaciens fsznc-06 or Bacillus pumilus fsznc-09, but that of multiple or potentially pathogenic bacteria were lower, as compared with the control group. Tax4Fun analysis predicting the functional profiling of microbial communities showed that microbial communities in rumen or caecum were highly influential on metabolism and organism systems after feeding weanling goats with Bacillus amyloliquefaciens fsznc-06 or Bacillus pumilus fsznc-09. It was suggested that Bacillus amyloliquefaciens fsznc-06 and Bacillus pumilus fsznc-09 might be an auspicious antibiotic alternative to improve black goat growth and health by changing rumen and gut microbiota positively.
Magnesium-Based Materials for Hydrogen Storage—A Scope Review

Magnesium hydride and selected magnesium-based ternary hydride (Mg2FeH6, Mg2NiH4, and Mg2CoH5) syntheses and modification methods, as well as the properties of the obtained materials, which are modified mostly by mechanical synthesis or milling, are reviewed in this work. The roles of selected additives (oxides, halides, and intermetallics), nanostructurization, polymorphic transformations, and cyclic stability are described. Despite the many years of investigations related to these hydrides and the significant number of different additives used, there are still many unknown factors that affect their hydrogen storage properties, reaction yield, and stability. The described compounds seem to be extremely interesting from a theoretical point of view. However, their practical application still remains debatable.
Integrating Patient‐Reported Outcomes Within Routine Hepatology Care: A Prompt to Action

Chronic liver disease (CLD) and its complications account for significant morbidity and mortality worldwide. Traditionally, clinical measures such as histologic stage of fibrosis and MELD (Model for End Stage Liver Disease) scores are used as surrogates of clinical outcomes to inform medical care. In contrast, measures assessing patients' experience with their liver disease and its treatment (Patient Reported Outcomes/PROs) are rarely used in hepatology practices.
United States County-level COVID-19 Death Rates and Case Fatality Rates Vary by Region and Urban Status

COVID-19 is a global pandemic with uncertain death rates. We examined county-level population morality rates (per 100,000) and case fatality rates by US region and rural-urban classification, while controlling for demographic, socioeconomic, and hospital variables. We found that population mortality rates and case fatality rates were significantly different across region, rural-urban classification, and their interaction. All significant comparisons had p < 0.001. Northeast counties had the highest population mortality rates (27.4) but had similar case fatality rates (5.9%) compared to other regions except the Southeast, which had significantly lower rates (4.1%). Population mortality rates were highest in urban counties but conversely, case fatality rates were highest in rural counties. Death rates in the Northeast were driven by urban areas (e.g., small, East Coast states), while case fatality rates tended to be highest in the most rural counties for all regions, especially the Southwest. However, on further inspection, high case fatality rate percentages in the Southwest, as well as in overall US counties, were driven by a low case number. This makes it hard to distinguish genuinely higher mortality or an artifact of a small sample size. In summary, coronavirus deaths are not homogenous across the United States but instead vary by region and population and highlight the importance of fine-scale analysis.
Formation of βTC3 and MIN6 Pseudoislets Changes the Expression Pattern of Gpr40, Gpr55, and Gpr119 Receptors and Improves Lysophosphatidylcholines-Potentiated Glucose-Stimulated Insulin Secretion

The impaired spatial arrangement and connections between cells creating islets of Langerhans as well as altered expression of G protein-coupled receptors (GPCRs) often lead to dysfunction of insulin-secreting pancreatic β cells and can significantly contribute to the development of diabetes. Differences in glucose-stimulated insulin secretion (GSIS) are noticeable not only in diabetic individuals but also in model pancreatic β cells, e.g., βTC3 and MIN6 β cell lines with impaired and normal insulin secretion, respectively. Now, we compare the ability of GPCR agonists (lysophosphatidylcholines bearing fatty acid chains of different lengths) to potentiate GSIS in βTC3 and MIN6 β cell models, cultured as adherent monolayers and in a form of pseudoislets (PIs) with pancreatic MS1 endothelial cells. Our aim was also to investigate differences in expression of the GPCRs responsive to LPCs in these experimental systems. Aggregation of β cells into islet-like structures greatly enhanced the expression of Gpr40, Gpr55, and Gpr119 receptors. In contrast, the co-culture of βTC3 cells with endothelial cells converted the GPCR expression pattern closer to the pattern observed in MIN6 cells. Additionally, the efficiencies of various LPC species in βTC3-MS1 PIs also shifted toward the MIN6 cell model.
Physiotherapy in Parkinson’s Disease: A Meta-Analysis of Present Treatment Modalities

Background Physiotherapy is a commonly prescribed intervention for people with Parkinson’s disease (PD). Conventional types of physiotherapy have been studied extensively, while novel modalities are being developed and evaluated. Objective To evaluate the effectiveness of conventional and more recent physiotherapy interventions for people with PD. The meta-analysis performed as part of the 2014 European Physiotherapy Guideline for PD was used as the starting point and updated with the latest evidence. Methods We performed a systematic search in PubMed, CINAHL, Embase, and Web of Science. Randomized controlled trials comparing any physiotherapy intervention with no intervention or sham treatment were included. Trials were classified into 12 categories: conventional physiotherapy, resistance training, treadmill training, strategy training, dance, martial arts, aerobic exercises, hydrotherapy, balance and gait training, dual tasking, exergaming, and Nordic walking. Outcomes included motor symptoms, balance, gait, and quality of life, and are presented as standardized mean differences. The GRADE (Grading of Recommendations, Assessment, Development and Evaluation) approach was used to systematically appraise methodological quality. Results A total of 191 trials with 7998 participants were included. Conventional physiotherapy significantly improved motor symptoms, gait, and quality of life. Resistance training improved gait. Treadmill training improved gait. Strategy training improved balance and gait. Dance, Nordic walking, balance and gait training, and martial arts improved motor symptoms, balance, and gait. Exergaming improved balance and quality of life. Hydrotherapy improved balance. Finally, dual task training did not significantly improve any of the outcomes studied. Conclusions This meta-analysis provides a comprehensive overview of the evidence for the effectiveness of different physiotherapy interventions in the management of PD, allowing clinicians and patients to make an evidence-based decision for specific treatment modalities. Further work is needed to directly compare the relative efficacy of the various treatments.
ACPS: An accurate bioinformatics tool for precision‐based anti‐cancer peptide generation via omics data

The anti‐cancer targets play a crucial role in the signaling processes of cells, and therefore, it becomes nearly impossible to engage these targets without affecting the native cellular function. Thus, an approach has been taken to develop an anti‐cancer Scanner (ACPS) tool aimed toward the recognition of anti‐cancer marks in the form of peptides. The proposed ACPS tool allows fast fingerprinting of the anti‐cancer targets having extreme significance in the current bioinformatics research. There already exist some tools that offer these features on a single platform; however, the performance of ACPS was compared with the preexisting online tools and was observed that ACPS offers greater than 95% accuracy that is comparatively much higher. The anti‐cancer marked sequences of proteins supplied by the operators are scanned against the anti‐cancer target datasets via ACPS and provide precision‐based anti‐cancer peptides. The proposed tool has been contrived in PERL programming language, and this tool is the extended version of A‐CaMP codes, which are highly scalable having an extensible application in cancer biology with robust coding architecture. The availability of tools like ACPS will greatly benefit researchers in the field of oncology and structure‐based drug design.
Mobile sex-tech apps: How use differs across global areas of high and low gender equality

Digital technologies are increasingly intertwined into people’s sexual lives, with growing scholarly interest in the intersection of sex and technology (sex–tech). However, much of the literature is limited by its over emphasis on negative outcomes and the predominance of work by and about North Americans, creating the impression that sex–tech is largely a Western phenomenon. Based on responses from 130,885 women in 191 countries, we assessed how women around the world interact with mobile technology for sex-related purposes, and whether in areas of greater gender inequality, technological accessibility may be empowering women with knowledge about sexuality. We investigated women’s use of technology to find sexual partners, learn about sex and improve their sexual relationships, and track their own sexual health. About one-fifth reported using mobile apps to find sexual partners. This use varied by region: about one-third in Oceania, one-fourth in Europe and the Americas, and one-fifth in Asia and Africa. Staying connected when apart was the most commonly selected reason for app use with a sexual partner. About one-third had used an app to track their own sexual activity. Very few reported that the app they used to improve their sexual relationships was detrimental (0.2%) or not useful (0.6%). Women in countries with greater gender inequality were less likely to have used mobile apps to find a sexual partner, but nearly four times more likely to have engaged in sending and receiving sexts. To our knowledge, this study provides the most comprehensive global data on sex–tech use thus far, demonstrates significant regional variations in sex-tech use, and is the first to examine women’s engagement in sex-related mobile technology in locations with greater gender disparities. These findings may inform large-scale targeted studies, interventions, and sex education to improve the lives of women around the world.
Online interprofessional simulation for undergraduate health professional students during the COVID-19 pandemic

ABSTRACT This report describes the Obstetric and Neonatal Simulation (ONE-Sim) workshop run in a remote learning format for medical and midwifery students in an interprofessional setting during the COVID-19 pandemic. It explores the observation of students as participants in the online learning of using Personal Protective Equipment and simulation-based learning of perinatal emergency management. This was followed by their mutual interaction and reflections. This paper aims to understand the role of synchronous remote learning through simulation and its impact on interprofessional interactions. We describe the experience of medical and midwifery students with the ONE-Sim workshop, facilitated by medical (obstetric and neonatal) and midwifery educators. Formal thematic analysis will be performed as part of the ongoing study; however, initial direct observation demonstrated that students reacted positively to the online ONE-Sim workshop and engaged well with facilitators and peers. Students mutually interacted amongst themselves, shared their previous experiences, knowledge of roles as medical and midwifery practitioners and how they see themselves in those roles in a perinatal emergency setting. The initial observations demonstrate that interprofessional education delivered in an e-learning format can be useful and meaningful, and may be utilized across a number of specialties.