Miracle-dz/UniFAR-FTUs huggingface dataset:
Roles of WNT6 in Sheep Endometrial Epithelial Cell Cycle Progression and Uterine Glands Organogenesis

The uterus, as part of the female reproductive tract, is essential for embryo survival and in the maintenance of multiple pregnancies in domestic animals. This study was conducted to investigate the effects of WNT6 on Hu sheep endometrial epithelial cells (EECs) and uterine glands (UGs) in Hu sheep, with high prolificacy rates. In the present study, Hu sheep with different fecundity, over three consecutive pregnancies, were divided into two groups: high prolificacy rate group (HP, litter size = 3) and low prolificacy rate group (LP, litter size = 1). A comparative analysis of the endometrial morphology was performed by immunofluorescence. RNA-seq was used to analyze the gene’s expression in endometrium of HP and LP Hu sheep, providing a candidate gene, which was investigated in EECs and organoid culture. Firstly, higher density of UGs was found in the HP Hu sheep groups (p < 0.05). The RNA-seq data revealed the importance of the WNT signaling pathway and WNT6 gene in Hu sheep endometrium. Functionally, WNT6 could promote the cell cycle progression of EECs via WNT/β-catenin signal and enhance UGs organogenesis. Taken together, WNT6 is a crucial regulator for sheep endometrial development; this finding may offer a new insight into understanding the regulatory mechanism of sheep prolificacy.
UV-B Radiation as Abiotic Elicitor to Enhance Phytochemicals and Development of Red Cabbage Sprouts

Background: The main objective of this study was to evaluate the effect of periodical UV-B illumination during red cabbage germination on morphological development and the phenolics and carotenoid accumulation. Methods: During a sprouting period of 10 days at 20 °C in darkness, seedlings received 5, 10, or 15 kJ m−2 UV-B (T5, T10, and T15) applied in four steps (25% on days 3, 5, 7, and 10). UV untreated sprouts were used as control (CTRL). After 10 days of germination, the sprouts were harvested and stored 10 days at 4 °C as a minimally processed product. Phenolic and carotenoid compounds were analysed 1 h after each UV-B application and on days 0, 4, 7, and 10 during cold storage. Results: The longest hypocotyl length was observed in T10-treated sprouts. The total phenolic content (TPC), total flavonoid content (TFC), and total antioxidant capacity (TAC) increased during germination following a sigmoidal kinetic, especially in the UV-B-treated samples, which reported a dose-dependent behaviour. In this way, T10-treated sprouts increased the TPC by 40% after 10 days at 4 °C compared to CTRL, while TAC and TFC increased by 35 and 30%, respectively. Carotenoids were enhanced with higher UV-B doses (T15). Conclusions: We found that UV-B stimulated the biosynthesis of bioactive compounds, and a dose of 10 kJ m−2 UV-B, proportionally applied on days 3, 5, 7, and 10 days, is recommended.
Wedge functions applied to 2D magnetostatic problems

In this paper the application of so called wedge functions is presented to solve two-dimensional simple geometries of magnetostatic and electrostatic problems, e.g. rec- tangles of varying aspect ratio and with different values of the magnetic permeability μ. Such problems require the use of surface charge density, or segment source, functions of the form D s = F a! 1 , where the power parameters, a, have special fractional values. A meth- odology is presented to determine these special values of a and use them in segment sources on simple geometries, i.e. rectangles of varying aspect ratio, and with different values of the magnetic permeability μ. Wedge solutions are obtained by coupling the strength coefficients of source segments of the same power around an edge.These surface source functions have been used in the analysis of conducting and infinite permeability structures. Here we apply such functions in a boundary integral analysis method to prob- lems having regions of finite permeability.
Source/drain contact resistance of silicided thin-film SOI MOSFET's

We developed a source/drain contact (S/D) resistance model for silicided thin-film SOI MOSFET's, and analyzed its dependence on device parameters considering the variation in the thickness of the silicide and residual SOI layers due to silicidation. The S/D resistance is insensitive to the silicide thickness over a wide range of thicknesses; however, it increases significantly when the silicide thickness is less than one hundredth of initial SOI thickness, and when almost all the SOI layer is silicided. To obtain a low S/D resistance, the specific contact resistance must be reduced, that is, the doping concentration at the silicide-SOI interface must be more than 10/sup 20/ cm/sup -3/. >
Study and Design of a New Over‐damped Cavity Kicker for the PEP II Longitudinal Feedback System

PEP‐II has been running for several years using drift‐tube style longitudinal kickers. They have functioned well at the design current in the HER and LER. Machine upgrade plans for PEP‐II have encouraged the analysis and design of cavity kickers for the longitudinal feedback systems in PEP‐II. The cavity kicker design is based on the use of an extremely low Q cavity, where the Q of the system is determined primarily by ridged waveguides coupling to external loads. This kicker design has originally developed at LNF‐INFN, and is attractive for use at PEP‐ II to reduce the kicker impedance at frequencies outside the working bandwidth and consequently reduce the strong beam‐heating of the structure and the feedthroughs. The cavity‐style kicker is also better suited to external cooling, as it is without internal elements which must be cooled through either radiation or conduction out through some path. The design options, including the choice of operating frequency (9/4*RF vs. 13/4*RF), the kicker shunt impeda.
Work & rewards in the virtual workplace : a "new deal" for organizations & employees

At Motorola, Inc., designers, engineers, and manufacturing experts are linked in a single production function that spans Chicago, Frankfurt, Singapore, and Beijing. This work takes advantage of the most qualified talent in the world and continues literally around the clock. In terms of innovation and accelerated speed-to-market, the old ways of working simply cannot compete.
Control of PMSG Wind Energy Conversion System with TS Fuzzy State-Feedback Controller

This paper presents a Takagi-Sugeno (TS) fuzzy state-feedback controller based on a linear matrix inequality (LMI) approach for the permanent magnet synchronous generator of wind energy conversion system (PMSG-WECS). A dc/dc converter is considered to regulate the maximum power output of the system. To show its effectiveness, the dynamic model is replaced by the TS fuzzy model, which the proposed controller can be applied to the PMSG-WECS, while the controller gains can be obtained by solving set of a LMI approach. The proposed controller guarantees the stability of the system. Therefore, the performance of the proposed TS fuzzy state-feedback controller is assessed through the computer simulation.
http://journal.uad.ac.id/index.php/TELKOMNIKA Improved fuzzy miner algorithm for business process

Info 2021 Return material authorization (RMA) is a process in which a company decides to repair or replace customer’s defect product during the warranty period. To execute RMA, both company and customer obliged to follow standard operating procedure (SOP) which usually consists of many business processes of a company well. As the business process could cause inefficiencies, a company should improve their business process regularly. The best way is using process discovery. This research proposes a new improved fuzzy miner algorithm to represent binary correlation between activities. This new algorithm utilizes binary significance and binary correlation equally to acquire fuzzy model. While the original fuzzy miner algorithm uses various binary correlation metrics, the improved fuzzy miner algorithm uses only one metric and could capture the fuzzy model, accurately based on the event logs to capture more accurate business process model. In this research, ProM fuzzy miner is used as a comparison to the proposed improved time-based fuzzy miner. The results showed that the improved algorithm has higher value on conformance checking and able to capture business process model based on time interval, by using only time-interval significance as a binary correlation
Assessing nutritional status and development of Pereskia aculeata Mill. affected by inoculation of Azospirillum brasilense combined with nitrogen rates

Abstract The interactive effect of Azospirillum brasilense inoculation and nitrogen (N) rates on Ora-pro-nobis (Pereskia aculeata Mill.) is poorly understood. Ora-pro-nobis (OPN) could be an important horticultural plant to promote a diverse and healthy diet to combat macronutrients and micronutrients deficiencies, particularly in developing countries. The objectives of this research were to assess the effect of inoculation with A. brasilense combined with N rates on OPN development, yield and leaf nutrients content under greenhouse conditions. Treatments were tested in a randomized completely block design with four replicates, arranged in a full factorial design 2 × 5 and included: i) two inoculations (with and without A. brasilense) and iii) five N application rates (0, 50, 100, 150 and 200 kg ha−1 applied in two split application as ammonium sulfate source). Inoculation with A. brasilense benefited OPN growth and development, leading to a greater leaf biomass, even combined or not with N application rates. In addition, A. brasilense inoculation increased OPN nutrition with increased leaf N, P, K, Ca, Mg, S, Fe and Zn concentrations. Azospirillum brasilense combined with 150 kg N ha−1 increased leaf biomass by 40% in sampling 1, and in sampling 2, A. brasilense inoculation increased leaf biomass by 8.8% regardless N application rates. Therefore, A. brasilense inoculation could be an important practice to increase OPN cultivation, development, nutrition and yield. Ora-pro-nobis showed high nutrient content in leaf tissue, therefore, OPN plant can be an interesting source of nutrients to human consumption. Nitrogen application rates benefited OPN growth and development leading to a greater leaf biomass. In addition, N application rates increased OPN nutrition with increased leaf N, P, Ca, Mg, S, Cu, Mn and Zn concentrations. However, increasing N rates decreased leaf K concentration. Therefore, long-term studies are required to better understand the role of A. brasilense under different N management and their effects on OPN development and nutritional properties, aiming to reduce N application rates and improve N management in OPN cultivation.
Distribution and correlation of Sabellidites cambriensis (Annelida?) in the basal Cambrian on Baltica

Abstract Sabellidites cambriensis is a tubular non-mineralized metazoan that appears as compressed ribbon-shaped imprints with transverse wrinkling, thick walls and an even tube diameter of up to 3 mm. The distribution of Sabellidites is investigated in three Ediacaran–Cambrian sections on the Digermulen Peninsula in Arctic Norway, spanning the Manndrapselva Member of the Stáhpogieddi Formation and the lower member of the Breidvika Formation. Here, the Ediacaran–Cambrian boundary is located in the lower part of the upper parasequence (third cycle) of the Manndrapselva Member. Specimens of Sabellidites are rare but consistently present close to the lowest level of Treptichnus pedum and upsection, whereas the taxon is common and abundant in the lower part of the lower member of the Breidvika Formation, with an upper record at c. 55 m above the base. The range is comparable with that of the GSSP section in Newfoundland, Canada, establishing Sabellidites as an index fossil for the lowermost Cambrian. In the Manndrapselva Member, Sabellidites co-occurs with the acritarch Granomarginata, indicative of the lowermost Cambrian Granomarginata Zone, whereas in the Breidvika Formation it co-occurs with Asteridium. Sabellidites is widely distributed in Baltica, through the Rovnian and Lontovan regional stages but confined to the Fortunian global stage. In its lower range, Sabellidites is associated with a Treptichnus pedum trace fossil association and a depauperate leiosphaerid acritarch assemblage, followed by a Granomarginata assemblage. In its upper range, Sabellidites co-occurs with acritarchs of the Asteridium–Comasphaeridium Zone and the tubular foraminiferan Platysolenites. In Baltica, Sabellidites is a useful index fossil.
D’addio to Blackness

It is assumed here that the energy of a strong gravitational field creates non-linear effects over enclosed masses. This idea and the rigorous rules of the General Theory of Relativity output a metric that covers strong and weak gravitational fields. The proposed metric could be correct because it included the Schwarzschild’s metric as a particular case and has no singularities. Addi-tionally, it appears here that the massive condition of the gravitational fields has properties like the so-called Dark Matter.
Fast Parameter-Free Multi-View Subspace Clustering With Consensus Anchor Guidance

Multi-view subspace clustering has attracted intensive attention to effectively fuse multi-view information by exploring appropriate graph structures. Although existing works have made impressive progress in clustering performance, most of them suffer from the cubic time complexity which could prevent them from being efficiently applied into large-scale applications. To improve the efficiency, anchor sampling mechanism has been proposed to select vital landmarks to represent the whole data. However, existing anchor selecting usually follows the heuristic sampling strategy, e.g. $k$ -means or uniform sampling. As a result, the procedures of anchor selecting and subsequent subspace graph construction are separated from each other which may adversely affect clustering performance. Moreover, the involved hyper-parameters further limit the application of traditional algorithms. To address these issues, we propose a novel subspace clustering method termed Fast Parameter-free Multi-view Subspace Clustering with Consensus Anchor Guidance (FPMVS-CAG). Firstly, we jointly conduct anchor selection and subspace graph construction into a unified optimization formulation. By this way, the two processes can be negotiated with each other to promote clustering quality. Moreover, our proposed FPMVS-CAG is proved to have linear time complexity with respect to the sample number. In addition, FPMVS-CAG can automatically learn an optimal anchor subspace graph without any extra hyper-parameters. Extensive experimental results on various benchmark datasets demonstrate the effectiveness and efficiency of the proposed method against the existing state-of-the-art multi-view subspace clustering competitors. These merits make FPMVS-CAG more suitable for large-scale subspace clustering. The code of FPMVS-CAG is publicly available at https://github.com/wangsiwei2010/FPMVS-CAG.
Global intercomparison of functional pyrodiversity from two satellite sensors

ABSTRACT Fires create substantial ecosystem disturbances, which affect biodiversity and climate processes. Previously, satellite-derived burned areas were assessed, and fire patches and morphological traits related to fire spread functions identified. The cut-off value in days is a critical parameter for the algorithms used to identify fire patches, as it identifies when two contiguous burned pixels should be grouped together as one patch. Our understanding of how fire patches and their morphologies change with the cut-off values between satellite sensors is currently insufficient for model development and pyrogeographic studies. We have addressed this using the FRY v1.0 global database of fire patch functional traits, with cut-off values of 3, 5, 9, and 14 days, derived from two burned area products, the MERIS Fire_cci version 4.1 and MODIS MCD64A1 collection 6, from two satellite sensors with different spatial and temporal resolutions. We intercompared the FRY products with functional diversity trait methods that assess their morphological pyrodiversity structures and dissimilarities. We have assessed the functional pyrodiversity of the FRY products with four cut-off values, for fire patches ≥ 300 ha, on 1° resolution tiles for the world and Global Fire Emissions Database (GFED) region scales, from 2005–2011. The functional structures and dissimilarities between the FRY products varied with the regions, while cut-off value sensitivity varied with the regions and between the satellite sensor products. These variations in functional structures and dissimilarities mirrored the regional fire spread processes and satellite sensor resolutions. The functional pyrodiversity that varied with the regions and similar cut-off values did not lead to the best agreement between the satellite sensor products. These variations reinforce the need to combine high temporal resolution optical sensors with radar in tropical regions, to consistently meet the monitoring requirements and for international organizations, to enable improved assessments of climate and biodiversity.
Single-mode fused biconical couplers for wavelength division multiplexing with channel spacing between 100 nd 300 nm

The authors report on single-mode fused biconical couplers tailored to the requirements of wavelength-division-multiplexing systems. The wavelengths of the two channels can be chosen arbitrarily for wavelength separations between 100 and 30 nm. For separations between 150 and 300 nm, the couplers can be manufactured with an accuracy of +or-5 nm at the two operating wavelengths. For decreasing wavelength separation of the channels, the influence of the state of polarization results in an increased inaccuracy of the two wavelengths, increased far-end crosstalk, and power fluctuations after the coupler. This sets a lower limit for channel separation. Good agreement between theory and experiment is achieved. >
Comparative Test Analysis for Determining Dynamic Deflection by Using GNSS/RTK, Trigonometric Leveling and Elevation of Sight

Respectively applied Trimble R8 GNSS/RTK, Leica TCA2003 3D coordinates measurement and SPRINTER 200M elevation of sight to synchronously monitor the deflection displacement of an underdamped oscillation, it has a 0.5 Hz design frequency and mm level amplitude in this test. Based on the FFT algorithm, spectral information was independently calculated out from these observed data of deflection displacement. Combined the spectrogram with the deflection displacement of R8, TCA2003 and SPRINTER 200M monitoring points, this paper makes a comparative analysis. The results show that the TCA2003 automatic tracking measurement can not only accurately measure the dynamic changes in the process of the damped oscillation dynamic deflection but truly reflect the structure of the dynamic deformation characteristics; the SPRINTER 200M digital leveling can monitor the overall trend of dynamic deflection, but get a harmonic frequency; and GNSS/RTK only acquires a harmonic.
All-optical network interface for bit synchronisation and regeneration

All-optical 100 ps bit synchronisation, format- and wavelength conversion with regenerative capabilities is demonstrated at 10 Gb/s with RZ or NRZ input signals and RZ output signals. Conversion penalties of -1 dB (NRZ-to-RZ) and +1.9 dB (NRZ-to-RZ) are reported.
Political Divisions and Socio-Economic Disparities in Poland: A Geographical Approach

This article attempts to identify the relationship between the persistent polarisation of political opinions and diverse levels of social and economic development. The coexistence of these phenomena may indicate a barrier to inclusive economic development, which connects with the United Nations Agenda for Sustainable Development. A research aim was to test two hypotheses: Hypothesis 1 (H1)—The increase in the spatial disparity of political support in Poland is persistent; and Hypothesis 2 (H2)—The spatial distribution of support for specific political options shows significant correlations with the distribution of social and economic growth. The study involves the following research methods implementation: desk research, intensity indicators and regression analysis. The results confirmed the persistence of spatial divisions in political support, whose distribution reflects to a large extent the diverse levels of social and economic development that exist. Two axes dividing Poland are identified, one between west and east and the other between urban and rural areas. The article connects with the international debate regarding “places that don’t matter” and the reasons behind the growing popularity of populist ideas in society.
Transglutaminase 2 mediates UVB‐induced matrix metalloproteinase‐1 expression by inhibiting nuclear p65 degradation in dermal fibroblasts

Matrix metalloproteinases (MMPs) play a key role in tissue remodelling by cleaving extracellular matrix (ECM) components. In the skin, UV irradiation increases expression of MMPs that causes dysregulation of ECM homeostasis in dermis, leading to acceleration of skin aging. However, the mediator(s) that links UV irradiation to the upregulation of MMPs have not been fully defined. Previously, we showed that UVB irradiation activated transglutaminase 2 (TG2) in keratinocytes, eliciting an inflammatory response by activating NF‐κB signalling. In this study, we reported the role of TG2 in mediating the UVB‐induced expression of MMP‐1. In human dermal fibroblasts, UVB irradiation enhanced the expression and activity of TG2, which in turn promotes the expression of MMP‐1. Analyses of MMP‐1 promoter showed that activation of the NF‐κB signalling pathway, rather than AP‐1, was responsible for the TG2‐mediated upregulation of MMP‐1. Moreover, Western blot analysis revealed that TG2 increased the activity of NF‐κB by inhibiting degradation of p65 in the nucleus. Furthermore, ex vivo skin from TG2‐knockout mice exhibited significantly reduced levels of MMP‐1 compared to that from wild‐type mice. These results indicate that TG2 functions as a mediator for the UVB‐induced expression of MMP‐1 in dermal fibroblasts, providing a new target for preventing skin photodamage.
Low loss ultra-smooth gold films for two-dimensional material plasmonic devices

The search for low loss plasmonic metals have been a long-standing research topic in the nanophotonics community. This issue becomes even more important for two-dimensional plasmonic devices as the light-matter interaction with twodimensional materials will be significantly suppresses by metal absorption due to their atomic thickness. In this paper, we have numerically demonstrated that light amplification may be achieved in a plasmonic resonant metasurface using a lower loss metal film. Using a modified template peeling method, we found that the gold films obtained by template peeling have a better three-dimensional morphology than those obtained by vapour deposition, while the gold films obtained by template peeling have a lower relative dielectric constant imaginary part in the 400-800 nm band as measured by ellipsometric polarisation. We expect that further improvement of the fabrication method for the low loss ultra-smooth plasmonic films will lead to the demonstration of high performance two-dimensional materials plamsonic devices such as lasers or spasers.