Miracle-dz/UniFAR-FTUs huggingface dataset:
Coda consonant production in French-speaking children

ABSTRACT This study examined coda production in French-speaking children, aged 2;6 to 6;10 (n = 141). The primary aim was to provide normative information on coda production with a large group of children. The secondary aim was to investigate factors which influence coda production such as age, manner and place of articulation, word length, word position, and bilingualism. Children took part in a word-naming task in which they produced words containing word-final and -medial codas. Results indicated that French-speaking children, as young as 2;6, produce word-final codas with a high degree of accuracy (i.e. 80%). Age had minimal effects on coda presence (i.e., whether a coda was realized or not) but it did influence coda accuracy (i.e. whether a coda was realized target-like). Older children had better coda accuracy scores than younger children. Manner of articulation influenced coda production: the younger children had the lowest scores for liquid and fricative codas whereas the older children, for fricative codas. A closer examination of coda production according to voicing revealed it was voiced obstruent codas which obtained low accuracy scores across age groups. Word-length influenced coda realization with the youngest age group producing codas more often in one- versus two-syllable words. Children produced codas more often in word-final versus word-medial position with the greatest differences evident in the youngest children. Bilinguals obtained better coda scores than monolinguals at the youngest ages and poorer ones at the oldest ages. The study concludes with a discussion of the clinical implications of the findings.
IoT-Based Proactive Energy Supply Control for Connected Electric Vehicles

The frequent stop-and-go operations require high and fast burst driving power, which accelerates the electric vehicle batteries degradation. Hybrid electric storage system (HESS) is a promising solution, which supplements the battery with supercapacitor for rapid charging/discharging. If future power demand is available, effective power management can be done by fully exploiting the HESS benefits. Recent advances in the Internet of Things (IoT) have made the future information prediction practical, since surroundings information is obtainable. In this paper, a proactive energy management strategy is developed for the HESS with the IoT support. By analyzing the traffic data, a probabilistic graphical model, i.e., the conditional linear Gaussian (CLG), is designed for future driving information prediction. Since, the CLG prediction results are probability distributions, a scenario-tree method is developed to approximate the future power demand by sampling the possible future velocity profiles from the results. A stochastic model predictive control problem is established by incorporating the sampled trajectories. A fast dual proximal gradient method is proposed to solve the problem and facilitate real-time implementation. Simulation results demonstrate that the magnitude and fluctuation of the battery discharging power are reduced by 46.4% and 27.7%, respectively, compared with the battery only case.
Representing two road traffic collisions in one Accimap: highlighting the importance of emergency response and enforcement in a low-income country

Abstract Seemingly erratic pedestrian crossing has become a major source of vehicle-pedestrian collisions on highways in Bangladesh, and across other low- and middle-income countries (LMICs). In this article, we approach the challenge from a sociotechnical systems perspective by using the Accimap method to analyse a pair of time-separated yet interconnected road traffic collisions. The first event involved a truck colliding with a road divider; in the second, fatal incident, a bus hit a university student. The traditional-style investigation conducted immediately after the collision apportioned blame to end users, that is, drivers and pedestrian; however, application of sociotechnical systems thinking revealed the contribution from lack of emergency response and enforcement among many other important factors. Results and recommendations are discussed in terms of reducing the chance and severity of such collisions across LMICs, and in terms of the need to look beyond the end-user, a focus that remains dominant in such settings. Practitioner summary: This paper applies sociotechnical systems thinking to pedestrian safety in Bangladesh by analysing two inter-connected road traffic collisions using a single Accimap. The findings emphasise the importance of implementing road safety interventions that target all system levels, and draw attention to the importance of post-collision response in low-income settings. Abbreviation: BUET: Bangladesh University of Engineering and Technology
Seasonality of Fruit-Feeding Butterflies (Lepidoptera, Nymphalidae) in a Brazilian Semiarid Area

A survey of 6,000 trap/hours using fruit-bait traps was conducted, in order to characterize the community of fruit-feeding butterflies and their seasonal variation in a semiarid area of NE Brazil, which exhibits a highly seasonal rainfall regime. The community was composed of 15 species, the four most abundant comprising more than 80% of the total individuals. In the first sampling month, 80% of the species had already been recorded. A strong positive correlation was found between butterfly abundance and precipitation of the sampled year. The highly seasonal pattern of the studied community may be related to the availability of both larvae and adult food resources. The endemic Fountainea halice moretta presented the highest positive correlations with other butterfly species and with total butterfly abundance and illustrates well the seasonal variation of the whole community. Hamadryas februa was the only species trapped in all sampling months, probably due to the ability of adults to aestivate during the dryer months. The open and more disturbed sample area showed higher abundance of butterflies in the rainy season and lower abundance in the dry season. Both abundance and richness were affected by season in a manner that the rainy period had significantly more individuals and species.
Optimization of tigecycline dosage regimen for different infections in the patients with hepatic or renal impairment

Abstract Objective The objective of this study was to investigate the cumulative fraction of response (CFR) of various tigecycline dosing regimens in patients with hepatic or renal impairment. Methods Monte Carlo simulations were performed using pharmacokinetic parameters and microbiological data to evaluate various tigecycline regimens in patients with hepatic or renal impairment. Results For HAP and cIAI, the regimen of 25 mg q12h achieved CFR values of >90% in Child-Pugh C patients against Gram-positive bacteria and partial Gram-negative bacteria (Escherichia coli and Klebsiella oxytoca). However, dose increases of tigecycline was mostly required for Enterobacter cloacae, Klebsiella pneumoniae and Acinetobacter baumanni. The conventional tigecycline regimen (50 mg q12h) was effective for HAP and cIAI caused by Gram-positive bacteria and Escherichia coli in patients with renal impairment. For HAP caused by Klebsiella pneumoniae and Enterobacter cloacae, patients with severe renal failure can use the standard dose regimen 50 mg q12h, and other patients need to increase the dose of tigecycline. However, when treating cSSSI caused by Acinetobacter baumannii, Enterobacter cloacae and Klebsiella pneumoniae, all tigecycline maintenance doses have a CFR <90%. Conclusions It is necessary to optimize tigecycline dosage regimens in patients with hepatic or renal impairment in order to maximise clinical response and minimise the probability of exposure-related toxicity.
Secondhand Smoke Risk Communication: Effects on Parent Smokers’ Perceptions and Intentions

This study examined effective strategies to communicate with parent smokers about the risks of secondhand smoke (SHS) exposure to children. An online, between-subjects experimental survey was administered via TurkPrime Panels to recruit participants (N = 623) comprising adult smokers living with children (aged 0–15). Participants were assigned to messages conditions that differed by message recommendation (cessation; cessation+exposure reduction) and format (video; text-only) or to a no-message control. Participants in a message condition viewed a message, and all participants responded to questions about their perceptions and intentions. Parent smokers who viewed either message recommendation reported greater harm perceptions (p <.001), self-efficacy (p <.001), and help-seeking intentions (p <.05) than the no-message control group. Cessation+exposure reduction recommendations elicited greater quit intentions than the no-message control (p <.05). Compared to text-only, videos elicited greater reduce-exposure intentions (p <.05) and interpersonal communication intentions (p <.05). Only videos elicited greater quit intentions (p <.01) and help-seeking intentions (p <.01) than the no-message control. Communication about this topic can be optimized by recommending both cessation and exposure-reduction behaviors (versus cessation only), and by using videos (versus traditional print/text-based materials).
A Wideband Circularly Polarized Antenna with Characteristic Mode Analysis

A wideband circularly polarized (CP) antenna is presented to achieve enhanced impedance, axial ratio (AR), and gain bandwidths. The antenna consists of two circular patches, a split-ring microstrip line with six probes, and a circular ground plane. By using these six probes which are placed in sequence on the split-ring microstrip line, the operating bandwidth of the proposed antenna is increased. The characteristic mode method is used to analyze different modes of the antenna and reveal the mechanism of extending the 3-dB AR bandwidth. Measured results show that the proposed antenna obtains an impedance bandwidth of 1.486–2.236 GHz (40.3%) for S11 ≤ −18 dB, a 3-dB AR bandwidth of 1.6–2.2 GHz (31.6%), and a boresight gain of 8.89 ± 0.87 dBic.
The Use of Latest Medical Technology and Taking Benefits from Technology to Treat Various Medical Diseases Including Covid-19 in the Current Pandemic

Background and Objective: The Main Aim of this article is to highlight the advancement of Medical Technology and technique in the twenty first century. The use of Latest Medical technology to serve the ill and sick people. Methods: The Author of this Article has done Literature Review, Comparison and Critical analysis of more than 20 Published Articles and other reviews. Author has chosen the Comparative Literature review as methodology for this research article. The purpose is to show that Randomly chosen articles are in favor to use Latest Medical Technology and taking benefits from technology to treat various medical diseases including COVID-19. SPSS 19 software is used to show Diagrammatic presentation for the results and analysis. Results: Author of this Article has used SPSS 19 Software to present the results. First SPSS Diagram shows that All selected 15 Articles favors the Importance of the use of Latest Medical Technology and taking benefits from technology to treat various medical diseases including COVID-19 in the current Pandemic. The Second SPSS Diagram shows that 15 Articles agreed 100% for the Importance of the use of Latest Medical Technology and taking benefits from technology to treat various medical diseases including COVID-19 in the current Pandemic. Conclusion: Latest Inventions in Science and Medical Technology are Blessing for all the Living being on this Planet Earth. From Human beings to Animals all are getting benefits to enjoy better health in twenty first century by modern treatment and surgical procedures for humans and Animals. The Human Doctor and Veterinary Doctor are getting modern medicines and technology to save the lives of their patients. Latest Medical Inventions for example Nuclear Medicine/ Nuclear scan, CT Scan, MRI Scan, Laparoscope Machine, Imaging Machine, Ultrasound, X Rays, ICU Facility with Ventilators, Endoscopy Instruments, Others are helping the Doctors and Patients to provide and receive latest Treatment for the ill and sick. Although the Advancement in Medical Technology and Sciences still a lot of Research and hard work needed as still scientists could not find the appropriate and proven treatment and Vaccine of COVID-19.
Analysis of genetic alterations identifies the frequent mutation of GNAS in colorectal laterally spreading tumors

Dear Editor, Colorectal cancer (CRC) is among the most commonly diagnosed cancer and the leading cause of cancer-related death worldwide [1]. Most CRCs develop from adenomas. Laterally spreading tumors (LSTs) are non-polypoid superficial colorectal neoplasms (CRNs) that are larger than 1 cm and typically extend laterally along the luminal wall. Based on surface morphology, it can be classified into a granular or nongranular type. The pathological morphology of LST manifests only as adenoma or with cancer. Recent studies have characterized 45-79% of LSTs as high-grade intraepithelial neoplasia (HGIN) or submucosal invasion; and the risk of submucosal invasion increases with lesion size [2]. Hence, LST is considered a precancerous CRC lesion. Patients with LSTs are usually asymptomatic and diagnosis typically occurs during physical examinations or screening colonoscopy. However, flat tumors are difficult to detect by colonoscopy and a missed
Peanut Allergenicity and Cross-Reactivity with Pea Proteins in the In Vivo Model

The aim of the study was to analyse the potential pea-peanut cross-reactivity using the mice BALB/c as a biological in vivo model in the research on immune response to peanut proteins (PnE). BALB/c mice were three-fold sensitised (on days 1, 7, and 21) by oral or intraperitoneal (IP) administration of PnE in 0.5 mg or 1 mg dose, with or without adjuvant - aluminum hydroxide gel (Alum). Serum immunoglobulins (IgE, IgG, IgG1 and IgG2a) and level of cytokines (IL-4, IL-10, IFN- γ), secreted by the isolated lymphocytes were examined. The highest increase in total IgE and peanut-specific IgG1 was noted in the group sensitised by IP administration of PnE in the presence of Alum. Lymphocytes from peanut-sensitised (with and without Alum) mice showed a significantly high level of IL-4 and this cytokine was secreted to a much higher extent as compared to IFN-γ. Stimulation of a culture of lymphocytes with pea proteins resulted in high IFN-γ secretion. A weak reaction of peanut-specific IgG1 present in mice serum with pea globulins (vicilin - PV and legumin - PL) can suggest that the cross-reactivity between peanut and pea proteins results from the presence of proteins other than 7S and 11S globulins. Due to the demonstrated low cross-reactivity between peanut proteins and pea globulins, the possibility of applying pea proteins in peanut-allergy immunotherapy may be suggested.
Validation of presence‐only models for conservation planning and the application to whales in a multiple‐use marine park

Abstract Identification of species’ Biologically Important Areas (BIAs) is fundamental to conservation planning and species distribution models (SDMs) are a powerful tool commonly used to do this. Presence‐only data are increasingly being used to develop SDMs to aid the conservation decision‐making process. The application of presence‐only SDMs for marine species’ is particularly attractive due to often logistical and economic costs of obtaining systematic species’ distribution data. However, robust model validation is important for conservation management applications that require accurate and reliable species’ occurrence data (e.g., spatially explicit risk assessments). This is commonly done using a random subset of the data and less commonly with fully independent test data. Here, we apply a spatial block cross‐validation (CV) approach to validate a MaxEnt presence‐only model using independent presence/absence survey data for a highly mobile, marine species (humpback whale, Megaptera novaengliae) in the Great Barrier Reef (GBR). A MaxEnt model was developed using opportunistic whale sightings (2003–2007) and then used to identify areas differing in habitat suitability (low, medium, high) to conduct a systematic, line‐transect, aerial survey (2012) and derive a density surface model. A spatial block CV buffering strategy was used to validate the MaxEnt model, using the opportunistic sightings as training data and independent aerial survey sightings data as test data. Moderate performance measures indicate MaxEnt was reliable in identifying the distribution patterns of a mobile whale species on their breeding ground, indicated by areas of high density aligned to areas of high habitat suitability. Furthermore, we demonstrate that MaxEnt models can be useful and cost‐effective for designing a sampling scheme to undertake systematic surveys that significantly reduces sampling effort. In this study, higher quality information on whale reproductive class (calf vs. non‐calf groups) was obtained that the presence‐only data lacked, while sampling only 18% of the GBR World Heritage Area. The validation approach using fully independent data provides greater confidence in the MaxEnt model, which indicates significant overlap with the main breeding ground of humpback whales and the inner shipping route. This is important when evaluating presence‐only models within certain conservation management applications, such as spatial risk assessments.
Contextualizing the Cultural Factors Associated With Cancer Care in Nigeria: An Ethnonursing Study

Introduction: Culture and care are two important phenomena of particular concern to transcultural nursing. Cancer care is generally affected by certain cultural factors that influence how cancer patients experience diseases and seek and utilize care services. This study aimed to explore the cultural factors that affect cancer care in a Nigerian cancer care institution. Method: This study adopted an ethnonursing method involving participant observation and individual interviews. The study was conducted in the oncology unit of University College Hospital, Nigeria. Seven nurses and six patients were key participants, while four physicians, three ward assistants, and six patients’ relatives constituted the general participants. Result: Two themes and five patterns were identified. Participants described how the interplay of several cultural factors influenced or inhibited cancer care. Findings revealed significant influence of kinship, family, and social structure as well as the roles played by cultural beliefs, values, and practices in cancer care in Nigeria. Discussion: Cultural factors need to be considered broadly for the efforts toward prevention, early diagnosis, and treatment of cancer to be effective in Nigeria.
Computational Identification of Alzheimer's Disease Specific Transcription Factors using Microarray Gene Expression Data

Alzheimer’s disease is the most common form of dementia affecting millions of older people world wide. Identification of transcriptional factor binding sites of disease specific co-expressed genes and the possible transcriptional regulation of the genes will lead to a better understanding of complex diseases such as Alzheimer’s disease. However, the regulatory mechanisms driving these changes, in particular the networks of transcription factors involved, is not fully understood to date. The computational identification of conserved TFBS in the regulatory regions of hundreds of genes at a time especially suited for microarray gene expression datasets. We report clusters of co-expressed genes and the identification of conserved TFBSs using microarray gene expression data sets. We investigated microarray gene expression data from Gene Expression Omnibus (GEO) specific to Alzheimer’s disease. The dataset consists of 14 normal and 14 Alzheimer disease samples. Differential expression analysis results 240 differentially expressed genes which are more significant. Hierarchical clustering of these significance genes shows eight clusters of co-expressed genes. The detection of over-represented transcription factor binding sites in the promoters regions of co-expressed genes reveals transcription factor binding site classes ZEB1, MZF1 1-4, ZNF354C, ELF5 and SPIB in upstream of human promoter and responsible for apoptosis.
A Systematic Review Analysis for Mobile Botnet Detection using GPS Exploitation

At present, mobile botnet has become a cyber threat for smartphone users especially on the Android platform. It has the capabilities to exploit the vulnerabilities and steal confidential information in the victim’s smartphone. Zeus, DroidDream and MisoSMS are examples of mobile botnets that have affected thousands of users worldwide. Therefore, this research paper presents a systematic review analysis on the existing techniques for mobile botnet detection techniques. It discusses the strengths and the weaknesses of the existing mobile botnet detection techniques and related works of mobile botnet that exploit GPS. This research paper can be used as a reference and guidance for those with the same interest.
Serum zonulin and claudin-5 levels in children with attention-deficit/hyperactivity disorder

Abstract Objective This study aimed to investigate serum zonulin and claudin-5 levels of children and adolescents with attention-deficit/hyperactivity disorder (ADHD) and healthy controls by controlling the parameters such as age, sex and body mass index (BMI) percentile which are known to affect these parameters. Method A total of 80 treatment-naive children and adolescents with ADHD and 40 healthy volunteer controls aged 8–12 years were enrolled in this study. The severities of ADHD symptoms were assessed via parent- and teacher-rated questionnaires. The severity of anxiety and depression symptoms of the children were assessed by the self-report inventories. Serum levels of zonulin and claudin-5 were measured using commercial enzyme-linked immunosorbent assay kits. Results The multivariate analysis of covariance (MANCOVA) revealed a significant main effect of groups in the serum zonulin and claudin-5 levels, an effect that was independent of age, sex and BMI percentile. Significant differences were found between the study groups in terms of serum log-claudin-5 levels. However, there was no significant difference between the study groups in terms of serum zonulin levels Conclusion These findings provide additional evidence for dysregulation of the blood–brain barrier, especially abnormalities in claudin-5 function, which may be involved in the aetiology of ADHD. Key points ADHD is one of the most common neurodevelopmental disorders of childhood. Although ADHD is quite common, its aetiology has yet to be fully explained. In recent years, studies on the relationship between intestinal and blood–brain brain barrier permeability and psychiatric disorders have increased. In our study, serum claudin-5 levels were higher in the ADHD group compared to the control group, while serum zonulin levels did not differ between the groups.