Miracle-dz/UniFAR-FTUs huggingface dataset:
Management Methods for Reducing Span Time during New Product Development

Shorter span time for new product development (NPD) has become a measure of success in the global marketplace. All of the present techniques to improve NPD: concurrent engineering, dedicated design teams, enhanced computer tools, etc., require excellent communication. A model of NPD was built to investigate parameters that affect communication and how they impact design project effort and span time. The model considered the effect of coordination in the form of task decomposition, allocation of resources, and information exchange methods upon information flow at the design team, system integration and project levels. The model was validated against present practices in aerospace companies. Results from simulations give insight into the impact of these coordination mechanisms on the span time and effort of NPD projects under various levels of uncertainty. The effects of coordination mechanisms at the project level were also tested. In particular, the use of the coordination principles from the Sprint method (Scrum) (highly employed in the software industry) during product design showed significant span time reduction for projects with moderate to high uncertainty. Other coordination mechanisms, such as the use of virtual data models during NPD, were also studied, and showed great promise for span time reduction.
Results from the first fully automated PBS-mask process and pelliclization

Automation is widely discussed in IC- and mask-manufacturing and partially realized everywhere. The idea for the automation goes back to 1978, when it turned out that the operators for the then newly installed PBS-process-line (the first in Europe) should be trained to behave like robots for particle reduction gaining lower defect densities on the masks. More than this goal has been achieved. It turned out recently, that the automation with its dedicated work routes and detailed documentation of every lot (individual mask or reticle) made it easy to obtain the CEEC certificate which includes ISO 9001.
Propiedades del hormigón de árido reciclado fabricado con adiciones, activa e inerte

El trabajo de investigacion presentado en este articulo describe las propiedades fisicas, mecanicas y de durabilidad de los hormigones fabricados con el 25% y 100% de arido grueso reciclado utilizando adiciones activa e inerte (microsilice y filler de escoria de arco electrico). La fase experimental realizada consta de dos etapas: En la etapa 1 se realizo un estudio fisico-mecanico (resistencia a compresion y velocidad de ultrasonido); En la etapa 2 se evaluo la durabilidad de los hormigones reciclados fabricados con adiciones mediante los ensayos de difusion de cloruros, resistividad, absorcion y porosidad, lo que permitio comparar los resultados con el hormigon convencional fabricado con similar dosificacion. Los resultados demuestran que los hormigones reci-clados obtienen propiedades fisicas y mecanicas inferiores al hormigon convencional. Sin embargo, la durabilidad del hormigon reciclado fabricado con adiciones activas mejora las propiedades del hormigon convencional.
PropellerHand: A Hand-Mounted, Propeller-Based Force Feedback Device

Immersive analytics is a fast growing field that is often applied in virtual reality (VR). VR environments often lack immersion due to missing sensory feedback when interacting with data. Existing haptic devices are often expensive, stationary, or occupy the user’s hand, preventing them from grasping objects or using a controller. We propose PropellerHand, an ungrounded hand-mounted haptic device with two rotatable propellers, that allows exerting forces on the hand without obstructing hand use. PropellerHand is able to simulate feedback such as weight and torque by generating thrust up to 11 N in 2-DOF and a torque of 1.87 Nm in 2-DOF. Its design builds on our experience from quantitative and qualitative experiments with different form factors and parts. We evaluated our final version through a qualitative user study in various VR scenarios that required participants to manipulate virtual objects in different ways, while changing between torques and directional forces. Results show that PropellerHand improves users’ immersion in virtual reality.
Impact of Mobile Internet on Employment and Income of Labourers: An Empirical Study Based on CFPS

2019 Government Work Report for the first time put employment priority as China's macro-level policy, employment will be placed in a more prominent position. Considering the rapid development of Mobile Internet, it is of epoch-making significance to study the impact of Mobile Internet on the employment and income of labourers. Based on the 2018 China Family Panel Studies data, a multiple regression model and a multiple probit model are established, and the Internet penetration rate of each province is used as a tool variable for 2SLS regression, this paper analyzes the impact of Mobile Internet on the employment and income of labourers. The study concludes that the use of mobile Internet can effectively promote the employment and increase the income of the labourers, thus proposing to vigorously develop the mobile internet industry and increase the penetration rate of the mobile Internet, to promote the efficiency of the labor market matching, and to strengthen the low-income, difficult-employment groups of mobile internet training and learning and other policy recommendations.
Exploration of the Relationship Between Shanghai Elementary School Climate and its Faculty Trust in Students and Parents

∗This study was a non-experimental research which has been conducted in Shanghai, China. It aims to explore the relationship between the Shanghai elementary school climate and the level of faculty trust in students and parents. This study also investigated whether the Shanghai elementary school climate can predict the development of faculty trust in students and parents. Thirty elementary schools of 726 teachers in Jiading District of Shanghai have participated in this study. The criterion variable was the faculty trust in students and parents. The predictor variable is the Chinese elementary school climate which has three constructs: collegial leadership, teacher professionalism, and academic press. The control variables are school types and faculty’s employment type. Results of this study indicated that faculty trust in students and parents is positively related to all three dimensions of Chinese elementary school climate. Despite of different school types and different faculty employment types, collegial leadership is the strongest predictor of faculty trust in students and parents.
Keratinocyte-intrinsic BCL10/MALT1 activity initiates and amplifies psoriasiform skin inflammation

Description BCL10/MALT1 signaling in keratinocytes is altered in human sporadic psoriasis and is a critical initiator and amplifier of skin inflammation in mouse models. Amplification of skin inflammation by BCL10/MALT1 BCL10 and MALT1 form ubiquitously expressed signalosomes that control immune and inflammatory pathways in many tissues. Pathological interplay between the immune system and keratinocytes is known to drive pathogenesis in psoriasis; however, the molecular and cellular functions of BCL10/MALT1 in the complex pathogenesis of psoriasis are not well defined. Kurgyis et al. engineered mouse models to specifically activate, inactivate, or attenuate BCL10/MALT1 signaling specifically in keratinocytes. They identified that BCL10 and MALT1 function to initiate and amplify keratinocyte responses to inflammatory cytokines and that constitutive activation of BCL10/MALT1 signaling in keratinocytes is sufficient to drive psoriasis. Furthermore, BCL10/MALT1 signaling is frequently altered in human psoriasis patients, suggesting that targeting the BCL10/MALT1 signalosome using MALT1 inhibitors may be a promising therapeutic approach to treat psoriasis. Psoriasis is a chronic inflammatory skin disease arising from poorly defined pathological cross-talk between keratinocytes and the immune system. BCL10 (B cell lymphoma/leukemia 10) and MALT1 (mucosa-associated lymphoid tissue lymphoma translocation protein 1) are ubiquitously expressed inflammatory signaling proteins that can interact with the psoriasis susceptibility factor CARD14, but their functions in psoriasis are insufficiently understood. We report that although keratinocyte-intrinsic BCL10/MALT1 deletions completely rescue inflammatory skin pathology triggered by germline Card14 gain-of-function mutation in mice, the BCL10/MALT1 signalosome is unexpectedly not involved in the CARD14-dependent interleukin-17 receptor (IL-17R) proximal pathway. Instead, it plays a more pleiotropic role by amplifying keratinocyte responses to a series of inflammatory cytokines, including IL-17A, IL-1β, and TNF. Moreover, selective keratinocyte-intrinsic activation of BCL10/MALT1 signaling with an artificial engager molecule is sufficient to initiate lymphocyte-mediated psoriasiform skin inflammation, and aberrant BCL10/MALT1 activity is frequently detected in the skin of human sporadic psoriasis. Together, these results establish that BCL10/MALT1 signalosomes can act as initiators and crucial amplifiers of psoriatic skin inflammation and indicate a critical function for this complex in sporadic psoriasis.
Influence of pitching and yawing during frontal passenger vehicle crash tests on driver occupant's kinematics and injury

Vehicle safety has become a major task in the development process of passenger vehicles. Measures for occupant safety are developed by reference to different tests including legal tests and consumer tests. The different load cases for the considered frontal crash tests cause different vehicle kinematics involving all six degrees of freedom. Besides restraint systems, vehicle kinematics shows distinct influence on occupant loading. A sensitivity analysis of the dummy responses due to varied motion fractions has been performed by finite elements simulations of a well-validated simulation model. The influences of particular motion components are determined by objective assessment variables. These are well-known injury criteria as well as geometrical criteria such as distances between dummy and interior. The results of this sensitivity study can be used for additional measures in terms of occupant protection.
Transforming OTA-C filters from voltage- to current-mode

A suitable method for transforming OTA-C filter circuits working in voltage-mode to current-mode is presented. First, the ideal behavior of the OTA is modeled using the nullor concept. Second, the transformation process is conducted by applying a set of four basic rules related to the interconnection pattern of the nullors. Third, the nullors of the transformed circuit are synthesized by OTAs. Finally, the computation of the transfer function of the given and the transformed circuit demonstrates the appropriateness of this method to be used as an analytical tool.
Developing a Partnership between the Riverina Environmental Education Centre and Charles Sturt University

A collaborative partnership has evolved between the Riverina Environmental Education Centre (REEC) and Charles Sturt University in Wagga Wagga. The Riverina Environmental Education Centre (REEC) is one of 24 Department of Education and Training environmental education centres in New South Wales (see www.reec.nsw.edu.au). As part of this partnership relationship, final year BTeach(Sec)/BSc students have worked with REEC and CSU staff on developing learning materials that support and enrich the programs offered through the REEC. In particular, these students have developed materials focussing on exploring student understanding about biodiversity and salinity. Additionally, the development of web based learning activities that use regional scientists as exemplars of current scientific research and possible career options (called Real Science) has occurred. Through this partnership arrangement, it has been a 'win-win' outcome for REEC staff, CSU staff and the CSU final year secondary science students with all participants gaining valuable insights and pedagogical understandings from the partnership.
GPF: A G REEN P OWER F ORWARDING T ECHNIQUE FOR E NERGY -E FFICIENT N ETWORK O PERATIONS

The energy consumption of network infrastructures is increasing; therefore, research efforts designed to diminish this growing carbon footprint are necessary. Building on prior work, which determined a difference in the energy consumption of network hardware based on their forwarding configurations and developed a real-time network energy monitoring tool, this research proposes a novel technique to incorporate individual device energy efficiency into network routing decisions. A new routing metric and algorithm are presented to select the lowest-power, least-congested paths between destinations, known as Green Power Forwarding (GPF). In addition, a network dial is developed to enhance GPF by allowing network administrators to tune the network to optimally operate between energy savings and network performance. To ensure the scope of this research for industry adoption, implementation details for different generations of networking infrastructure (past, present, and future) are also discussed. The experiment results indicate that significant energy and, in turn, cost savings can be achieved by employing the proposed GPF technique without a reduction in network performance. The future directions for this research include developing dynamically-tuning network dial modes and extending the principles to inter-domain routing.
CLASSIFICATION COCO DATASET USING MACHINE LEARNING ALGORITHMS

In this paper, we used four classification methods to classify objects and compare among these methods, these are K Nearest Neighbor's (KNN), Stochastic Gradient Descent learning (SGD), Logistic Regression Algorithm(LR), and Multi-Layer Perceptron (MLP). We used MCOCO dataset for classification and detection the objects, these dataset image were randomly divided into training and testing datasets at a ratio of 7:3, respectively. In randomly select training and testing dataset images, converted the color images to the gray level, then enhancement these gray images using the histogram equalization method, resize (20 x 20) for dataset image. Principal component analysis (PCA) was used for feature extraction, and finally apply four classification methods, the results indicate that MLP was better than others with precision 81% , it took the maximum execution time for processing of the data-sets.
Research on Supply Chain Integration under Service-oriented Logics and Joint Influence of Dual Innovation on Corporate Performance Path -- Empirical Analysis of FsQCA based on Manufacturing Enterprise Data

The rapid development of economic globalization and the promotion of emerging technologies have spawned a Service-oriented logic that gradually dominates the contemporary industry, and the path for manufacturing companies to improve performance has become more and more complicated. Based on this background, the article uses the data of A-share listed companies in the manufacturing industry in the Yangtze River Delta and the Pearl River Delta in 2019, and uses the research method of fuzzy set qualitative comparative analysis to empirically study the core path and mechanism of multiple complex factors that affect corporate performance. The research results show that manufacturing companies can choose four paths to improve corporate performance (supply chain integration-driven based on internal control, servicing and market dual logic based on internal control-based integration-driven, relying on exploration and innovation-based integrationdriven, Relying on the integration-driven type of dual innovation and balance), and found that the core role of supply chain integration and servicing level has become more prominent, becoming a key factor leading to high corporate performance. This research is helpful to identify the influence mechanism of supply chain integration, service level and other factors on corporate performance, and grasp the core of configuration, which has certain reference significance for corporate managers.
A new species of Amphipyra Ochsenheimer, 1816 from Taiwan, with description of larva, pupa and biology (Lepidoptera, Noctuidae, Amphipyrinae) 1

: The new species Amphipyra meifengensis sp. n. (holotype female, in National Museum of Natural Science Tai wan, Taichung, belonging to the species­group of A. py ra­ mi dea (Linnaeus, 1758)) is decribed from Meifeng in the cen tral high mountains of Taiwan. A larva of the new spe­ cies was found and successfully reared so that information on the biology and morphology of larva and pupa could be ad ded. All hitherto known Amphipyra ­species, especially those known from Taiwan, can be easily discriminated from this new species
Development of new advanced low pressure end blades for high efficiency steam turbine

A low pressure end blade is one of the most important elements in designing the steam turbine, because it determines the performance, the dimension, and the number of casings of the turbine. Applying the state of the art technology to the aerodynamic and mechanical design, Mitsubishi Heavy Industries, Ltd. has been conducting a development program of new advanced low pressure end blades which adopt the ISB (Integral Shroud Blade) structure. A new standard series of these low pressure end blades has already been completed for 50 Hz and 60 Hz unit application including 3 600 rpm 45 inch titanium blade, 3 000 rpm 48 inch steel blade, and 1500/1800 rpm 54 inch steel blade which have the largest exhaust annulus area among the same class blades in the world. This paper reports on the up-to-date design technology applied to the new advanced low pressure end blades and on the verification tests to ensure the high efficiency and the reliability of the developed blades
Andrographolide inhibits non-small cell lung cancer cell proliferation through the activation of the mitochondrial apoptosis pathway and by reprogramming host glucose metabolism

Background The main aim of this research was to explore the role and mechanism of Andrographolide (Andro) in controlling non-small cell lung cancer (NSCLC) cell proliferation. Methods Human NSCLC H1975 cells were treated with Andro (0–20 µM) for 4–72 h. B-cell leukemia/lymphoma 2 (Bcl-2)-antagonist/killer (Bak)-small interfering RNA (siRNA) (Bak-siRNA) and fructose-1,6-bisphosphatase (FBP1)-siRNA were transfected into H1975 cells to inhibit the endogenic Bak and FBP1 expression, respectively, and their expressions were detected by real-time quantitative reverse transcription–polymerase chain reaction (qRT-PCR) and western blotting (WB). Cellular proliferation ability was determined through various assessments, including 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT), colony formation, and cell counting kit-8 (CCK-8) assays. Cell apoptosis ability was measured using flow cytometry. Pro-apoptotic-related proteins (cleaved caspase 9, cleaved caspase 8, and cleaved caspase 3) and mitochondrial apoptosis pathway proteins [Bcl2-associated X (Bax), Bak, Bcl-2, and cytochrome C (cyto C)] were assessed by WB. Aerobic glycolysis-associated genes [pyruvate kinase M2 (PKM2), lactate dehydrogenase A (LDHA), and glucose transporter 1 (GLUT1)] and gluconeogenesis genes [phosphoenolpyruvate carboxykinase 1 (PEPCK1), fructose-1,6-bisphosphatase 1 (FBP1), and phosphofructokinase (PFK)] were measured by qRT-PCR. The mitochondrial membrane depolarization sensor, 5, 50, 6, 60-tetrachloro-1, 10, 3, 30 tetraethyl benzimidazolo carbocyanine iodide (JC-1) assay was used for the measurement of mitochondrial membrane potential (ΔΨm). Additionally, glycolytic metabolism, lactate production, and adenosine triphosphate (ATP) synthesis were also analyzed. Results Andro inhibited human NSCLC cellular proliferation and induced apoptosis in a dose-time or dose-dependent manner via activation of the mitochondrial apoptosis pathway. Andro inhibited glycolysis, promoted the gluconeogenesis pathway, and increased the levels of cleaved caspase 9, cleaved caspase 8, cleaved caspase 3, Bax, Bak, PEPCK1, FBP1, and PFK, and decreased the levels of Bcl-2, PKM2, LDHA, and GLUT1. Moreover, it also decreased the ΔΨm and facilitated the release of cyto C from mitochondria into the cytoplasm. Furthermore, Andro enhanced the mitochondrial translocation of Bak, glucose uptake, lactate release, and intracellular ATP synthesis. Suppression of endogenic Bak and FBP1 expression significantly reduced the effects of Andro in H1975 cells. Conclusions Andro represses NSCLC cell proliferation through the activation of the mitochondrial apoptosis pathway and by reprogramming glucose metabolism.
Thermal sensitivity in dual‐breathing ectotherms: Embryos and mothers determine species' vulnerability to climate change

Understanding the life‐stage specific vulnerability of ectotherms to temperature increases is crucial to accurately predicting the consequences of current and future global climate change. Here, we examined ontogeny‐specific thermal vulnerability of three intertidal, bimodal (i.e., air and water) breathing crabs from tropical and warm temperate latitudes to address this issue. Spawning females and embryos of intertidal crabs from warm temperate latitudes were more vulnerable to temperature increases than tropical conspecifics, particularly in water. Our findings do not fully support the Climate Variability Hypothesis for setting upper thermal limits, but correspond with the Oxygen‐ and Capacity‐Limited Thermal Tolerance hypothesis, suggesting ontogeny‐specific aerobic capacity dictates overall species' thermal sensitivity. Bimodal breathing efficiency as an evolutionary adaptation, ontogenetic stage and local climate adaptation are therefore significant factors to consider when evaluating the vulnerability of intertidal ectotherms to temperature increases and the consequences of climate changes for intertidal organisms, populations and communities.
Scientific contributions and learning experiences of citizen volunteers with a small cat project in Sanjay Gandhi National Park, Mumbai, India

We conducted a project on small wild cats in Sanjay Gandhi National Park near Mumbai during 2017–2019 with the participation of 35 citizen volunteers. Volunteers underwent a training period after which they collected scat samples, placed camera traps and participated in data analysis. Volunteers answered a questionnaire to gauge the impact the program had in furthering their interests and knowledge. Nineteen participants responded to the feedback survey. Most indicated an increase in their knowledge of wildlife research, conservation issues and small wild cats. We discuss the value of research projects where citizens can actively participate and learn semi-technical skills.
GIS-KG: building a large-scale hierarchical knowledge graph for geographic information science

ABSTRACT An organized knowledge base can facilitate the exploration of existing knowledge and the detection of emerging topics in a domain. Knowledge about and around Geographic Information Science and its associated system technologies (GIS) is complex, extensive and emerging rapidly. Taking the challenge, we built a GIS knowledge graph (GIS-KG) by (1) merging existing GIS bodies of knowledge to create a hierarchical ontology and then (2) applying deep-learning methods to map GIS publications to the ontology. We conducted several experiments on information retrieval to evaluate the novelty and effectiveness of the GIS-KG. Results showed the robust support of GIS-KG for knowledge search of existing GIS topics and potential to explore emerging research themes.