Miracle-dz/UniFAR-FTUs huggingface dataset:
Towards improving the absolute accuracy of lightweight robots by nonparametric calibration

In this work, preparations for the nonparametric calibration of a 7 DOF light-weight robot using machine learning techniques are presented. The approach was developed to satisfy the requirements on absolute accuracy for robot-assisted surgery. With the kinematic and non-kinematic properties in mind, we showed that a decomposition of the robot's kinematic chain can drastically reduce the number of necessary samples for a sophisticated training set. Thus, the data acquisition can be accomplished in a feasible time frame. Furthermore, we cope with the problem of data registration between the robot's internal model and the external measurements. We can show that by carefully choosing the split point for the decomposition, errors caused by the dependency between sub-chains of the robot are small enough to yield satisfying results.
Antiflammin-2 Activates the Human Formyl-Peptide Receptor Like 1

The anti-inflammatory actions of the nonapeptide antiflammin-2, identified by homology with uteroglobin and annexin-A1 sequences, have been described in some detail, yet its mechanisms of action remain elusive. Since recent data indicate an involvement of the formyl peptide receptor (FPR)-like 1 (or FPRL-1) in the effects of annexin-A1, we have tested here the effect of antiflammin-2 with respect to this receptor family. Using HEK-293 cells expressing either human FPR and FPRL-1, and an annexin-A1 peptide as tracer ([125I-Tyr]-Ac2-26), we found that antiflammin-2 competed for binding only at FPRL-1, and not FPR, with an approximate EC50 of 1 μM. In line with data produced for the full-length protein, genuine receptor activation by antiflammin-2 was confirmed by rapid phosphorylation of extracellular-regulated kinase 1 and 2. Finally, study of the neutrophil interaction with activated endothelium under flow demonstrated an inhibitory effect of antiflammin-2, thus providing functional support to a role for the antiflammin-2/FPRL-1 anti-inflammatory axis.
A Dirichlet Process Mixture Based Name Origin Clustering and Alignment Model for Transliteration

In machine transliteration, it is common that the transliterated names in the target language come from multiple language origins. A conventional maximum likelihood based single model can not deal with this issue very well and often suffers from overfitting. In this paper, we exploit a coupled Dirichlet process mixture model (cDPMM) to address overfitting and names multiorigin cluster issues simultaneously in the transliteration sequence alignment step over the name pairs. After the alignment step, the cDPMM clusters name pairs into many groups according to their origin information automatically. In the decoding step, in order to use the learned origin information sufficiently, we use a cluster combination method (CCM) to build clustering-specific transliteration models by combining small clusters into large ones based on the perplexities of name language and transliteration model, which makes sure each origin cluster has enough data for training a transliteration model. On the three different Western-Chinese multiorigin names corpora, the cDPMM outperforms two state-of-the-art baseline models in terms of both the top-1 accuracy and mean F-score, and furthermore the CCM significantly improves the cDPMM.
Design of Image Acquisition and Processing Based on FPGA

The digital image acquisition and processing technology already mature also in domains and so on visual communication obtains day by day[1]. However, the image acquisition and processing technology had many kinds, for example white balance processing and image denoising methods. The traditional image acquisition and processing systems are implemented using software by the PC or DSP chip[2], and sometimes software in series can not meet the requirement of high speed image processing. this article has given FPGA in the image acquisition and processing simple application, applied FPGA in the image acquisition and processing to be possible to enhance the image processing the speed, reduced takes the logical unit. The system designed by above-mentioned way achieves a satisfying effect by experimental verification.
Operation, Valuation and Electricity Sourcing for a Generic Aluminium Smelter

Electricity prices vary across different geographic locations and affect the relative cost position of individual aluminium producers. Understanding the scope of electricity price risk is thus of high importance to industry players. We propose a sequential valuation and optimisation approach for investigating the relationship between operating policy, electricity sourcing and smelter value. The hybrid optimisation approach determines a heuristic operating policy with the least squares Monte Carlo (LSM) method and uses portfolio optimisation to find a corresponding electricity procurement scheme. We find that the resulting procurement scheme reduces the risk of shutdowns without compromising smelter value. In addition, the procurement scheme obtained when using demand derived from the heuristic operating policy outperforms the one found when treating demand as constant. Our findings show that there is substantial value in operational flexibility and suggest that decisions on electricity sourcing should be coupled with the operating policy. This could motivate the industry to adapt a valuation approach that captures the full value of operational flexibility and yields a corresponding operating policy.
A Protective and Broadly Cross-Neutralizing Epitope of Human Papillomavirus L2

ABSTRACT We generated a monoclonal antibody, RG-1, that binds to highly conserved L2 residues 17 to 36 and neutralizes human papillomavirus 16 (HPV16) and HPV18. Passive immunotherapy with RG-1 was protective in mice. Antiserum to the HPV16 L2 peptide comprising residues 17 to 36 (peptide 17-36) neutralized pseudoviruses HPV5, HPV6, HPV16, HPV 18, HPV31, HPV 45, HPV 52, HPV 58, bovine papillomavirus 1, and HPV11 native virions. Depletion of HPV16 L2 peptide 17-36-reactive antibodies from cross-neutralizing rabbit and human L2-specific sera abolished cross-neutralization and drastically reduced neutralization of the cognate type. This cross-neutralization of diverse HPVs associated with cervical cancer, genital warts, and epidermodysplasia verruciformis suggests the possibility of a broadly protective, peptide-based vaccine.
The Effects of Psychosocial Stress on Heart Rate Variability in Panic Disorder

Background: Since panic is characterized by stress-induced autonomic cardiac sensations, such as increased heart rate and palpitations, effects of experimental psycho-social stress on heart rate variability are of interest. Methods: 25 patients with a current panic disorder and 25 healthy controls matched by age and sex underwent the Trier Social Stress Test on two consecutive days. Heart rate and heart rate variability (HRV) were assessed before and during test performance as well as under recovery conditions. Results: An increase of heart rate was observed in both patients suffering from panic disorder and in healthy controls under conditions of experimental psycho-social stress. Root mean square successive differences (RMSSD), a time domain parameter of HRV, was decreased in both groups of participants during the stress conditions. Low frequency/high frequency ratio (LF/HF), a frequency domain parameter of HRV, was found increased in patients with panic disorder when performing the Trier Social Stress Test whereas no such change was found in healthy controls. Conclusions: Induction of psychosocial stress increases heart rate and impairs heart rate variability. The latter effect reflects activation of the sympathetic and/or inhibition of the parasympathetic autonomous nervous system (ANS) that is more pronounced in patients suffering from panic disorder than in healthy controls (German J Psychiatry 2010; 13 (2): 66-73).
Some quality aspects of fish patties prepared from an Indian major carp, Labeo rohita (Ham.)

Six different types of fish patties were prepared from de-boned meat of three weight groups (250–500 g, 501–750 g, and 751–1,000 g) of an Indian major carp, Labeo rohita, using two extenders (boiled potato and corn flour). The weight of the fish and the type of the extender affected the nutritional quality of the patties. Cooking lowered the crude protein but increased the total lipid, total soluble sugars, and gross energy contents of the patties. Cooking yield increased with an increase in the weight of the fish. Similarly, the use of corn flour as the extender resulted in a higher cooking yield and higher fat retention capacity than boiled potato. The type of extender had no effect on the water-holding capacity of the patties. The weight of the fish and the extender had no significant effect on appearance, colour, flavour, taste, and the overall acceptability of the product. However, the patties prepared from 250–500 g and 501–750 g weight groups with corn flour as the extender had a significantly higher score for their texture. The total plate count suggested that the patties were safe (from microbiological point of view) up to a storage period of 80 days.
RNA blots: staining procedures and optimization of conditions.

Two critical factors which determine the success of an RNA blot are: i) assessment of the integrity and amount of RNA loaded per lane; and ii) the localization of major RNA species to be used as size markers. We provide two methods to stain major RNA species in gels or blots, assess their sensitivity, and determine what effect they have on hybridization efficiency. We also compare the hybridization signal obtained when RNA is affixed to a membrane by baking or by u.v. cross-linking.
Comparison of the Effect of the Regional Ischemia, Hypoxia, Hyperkalemia, and Acidosis on Intracellular and Extracellular Potentials and Metabolism in the Isolated Porcine Heart

DC electrograms and transmembrane potentials were recorded from isolated perfused pig hearts.Regional ischemia was produced by clamping the left anterior dascending artery (LOD), and after a reperfusion period, regional hypoxic, glucose-free solutions (with or without acidification, or high K+) or with normoxic high K+ solutions. In transmural biosies, nucleotides, lactate, and K+ were determined. During ischemia, resting potential decrease (T-Q depression), action potential amplitude and upstroke velocity decrease, and local activation is markedly delayed (S-T elevation, late intrinsic deflection, high R wave). A high K+ concentration, up to 13 mM, decrease resting potential (T-Q depression) and shortens the action potential (positive T wave) but has minor effect on amplitude (no S-T elevation) and activation (no delay). Hypoxin (Poz=7 mm Hg, no glucose) causes a moderate decrease in resting potential, marked action potential shortening, and some of loss of amplitude but no or only minor delay in activation (slight T-Q depression and S-T elevation, positive T waves). Acidle perfusate does not influence changes fin transm,embrane potential during hypoxia. Potentials of similar configuration to those seen during ischemia could be obtained by LAD perfusion with hypoxic, glucose-free, high K+(10 mM), acidic (pH 6.8) solutions. Most surprising was improvement of potentials after 20 minutes of perfusion, like that seen during maintained LAD occlusion. The time course of metabolic changes was the same in hypoxia and ischemia. Results indicate (1) that there is no direct relationship between metabolic and electrical changes, (2)that electrical changes during ischemia are caused by a combination of lack of perfusion (hypoxia, no substrate) and lack of washout (hyperkalemia, acidosis), and (3) that action potentils of ischemic cells are more “depressed” than those of normoxic cells, at similar reduced levels of resting membrane potential. Circ Res 46: 634-646, 1980.
Cyber security for younger demographics: A graphic based authentication and authorisation framework

Contemporary computing environments are increasingly moving towards BYOD (Bring Your Own Device) configurations, particularly in primary and high school settings. While ‘preferred’ configurations are suggested usually there is a diverse array of devices connecting to an organizations infrastructure, along with a diverse range of ‘first time’ users, thus causing significant security issues. Additionally, the users in these environments are generally uneducated in the field of cyber security, resulting in weak passwords and poor data protection practices. This paper presents a novel authentication and authorization framework to address this problem. Specifically, by providing graphical based user friendly authentication and authorization schemes tailored to the younger demographic.
Scaling and branching in wet sonogels as a function of the volume fraction of the liquid phase

The structural properties of wet silica sonogels prepared with different volume fractions of the liquid phase were studied by small-angle x-ray scattering (SAXS) and thermogravimetry (TG). The SAXS intensity curves of aged wet gels were all found to be well fitted by the form factor for scattering from non-randomly branched polymers in solution. The radius of gyration (Rg) of the polycondensates and the branching density were found to increase with the volume fraction of the liquid phase of the wet gels. The molecular weight (M) of the branched polycondensates was found to scale as M∼Rgα with α quite close to 2 in the studied range.
The Central Role of a SNRK2 Kinase in Sulfur Deprivation Responses1[W][OA]

In the absence of sulfur (S), Chlamydomonas reinhardtii increases the abundance of several transcripts encoding proteins associated with S acquisition and assimilation, conserves S amino acids, and acclimates to suboptimal growth conditions. A positive regulator, SAC1 (for sulfur acclimation protein 1), and a negative regulator, SAC3, were shown to participate in the control of these processes. In this study, we investigated two allelic mutants (ars11 and ars44) affected in a gene encoding a SNRK2 (for SNF1-related protein kinase 2) kinase designated SNRK2.1. Like the sac1 mutant, both snrk2.1 mutants were deficient in the expression of S-responsive genes. Furthermore, the mutant cells bleached more rapidly than wild-type cells during S deprivation, although the phenotypes of ars11 and ars44 were not identical: ars11 exhibited a more severe phenotype than either ars44 or sac1. The phenotypic differences between the ars11 and ars44 mutants reflected distinct alterations of SNRK2.1 mRNA splicing caused by insertion of the marker gene. The ars11 phenotype could be rescued by complementation with SNRK2.1 cDNA. In contrast to the nonepistatic relationship between SAC3 and SAC1, characterization of the sac3 ars11 double mutant showed that SNRK2.1 is epistatic to SAC3. These data reveal the crucial regulatory role of SNRK2.1 in the signaling cascade critical for eliciting S deprivation responses in Chlamydomonas. The phylogenetic relationships and structures of the eight members of the SNRK2 family in Chlamydomonas are discussed.
Plane circular gradient grating that combines the functions of a spherical mirror and a focusing lens

In this paper, the modeling of the wave front in the interaction of electromagnetic radiation with plane circular metallic gradient gratings is presented. It is shown that a plane circular gradient grating whose filling factor increases in the direction from the center to the edges has the properties of a concave partially transparent mirror and a focusing lens. These properties can be useful for the use of such gratings as output mirrors of terahertz lasers. Such mirrors allow to reduce the diffraction losses inside the resonator and to compensate for the diffraction divergence of the output laser radiation.
Oxidation reduction potential of developing plaque, periodontal pockets and gingival sulci.

The role of microbial flora in the initiation of perio­ dontal disease is not completely understood, but there is strong supportive evidence that bacterial plaque is an important etiologic factor in human periodontal dis­ ease. Changes in the ecology of bacterial plaque have been related to the initiation of inflammatory changes in the gingival tissues by Löe, et a l 1 who showed that the appearance in developing plaque of two anaerobic or­ ganisms was accompanied by the first clinical evidence of inflammation in previously normal gingiva. R i t z 2 re­ ported similar population shifts in developing human dental plaque with the initial predominant organisms being aerobic, while after seven days the predominant organisms were anaerobic. Further he suggested that these changes in plaque ecology were related at least in part to a lowering of the oxidation reduction potential of the environment.2
Interprofessional collaboration within teams comprised of health and other professionals: a systematic review of measurement tools and their psychometric properties

Background and Purpose: Measuring collaboration within interprofessional teams allows professionals to evaluate their practice, set benchmarks and improve outcomes. In the context of healthcare, most research has focused on teams comprised solely of health professionals, with limited attention given to collaboration between health and other professionals. Given the escalating complexities of healthcare, and the growing need for interprofessional collaborative practice involving team members external to health care, this represents a considerable gap in the literature. Therefore, the purpose of this review was to identify tools that measure collaboration within interprofessional teams comprised of members from health and other disciplines, and evaluate their psychometric properties. This review focused on the area of children’s services, to assist professionals working in this area with their collaborative practice. Methods: A systematic search including nineteen electronic databases was conducted. Eleven articles (describing ten tools) were identified for inclusion and were critically appraised. Results: Overall, it was found that few psychometrically sound tools exist for more diverse professional groups working together. The PINCOM-Q was found to be the most appropriate tool for the context of children’s services, and with the highest critical appraisal score, as reported. Conclusions: Recommendations are made for further development of existing tools before practical implementation. Further research could develop new and innovative tools to accommodate the evolving composition of future interprofessional teams.
Comparative analysis of visual category learning

Introduction Categorization is critical for our ability to organize information. A comparative analysis may provide important insights into the cognitive and neural mechanisms underlying category learning. We have examined category learning in rats and pigeons because of differences in brain organization between mammals and birds. Species differences in category learning and representation can indicate how the differences in brain organization lead to differences in cognition. Category structure and supervision are factors importantly influencing category learning and representation in humans (Kloos & Sloutsky, 2008; Love, 2002). Humans can learn categories with dense defining features with no supervision, but we need supervision to learn categories with sparse features. These finding have been interpreted as evidence for multiple category learning systems in the brain. The current study examined the roles of feature density and supervision in visual category learning in rats and pigeons.
Isolation and characterization of Caulobacter mutants impaired in adaptation to stationary phase

The entry into stationary phase causes a change in the pattern of gene expression of bacteria, when the cells must express a whole set of genes involved mainly with resistance to starvation and to environmental stresses. As an attempt to identify genes important for the survival of Caulobacter crescentus in stationary phase, we have screened a library of 5,000 clones generated by random transposon mutagenesis for mutants that showed reduced viability after prolonged growth. Four clones were selected, which displayed either lower viability or a longer time of recovery from stationary phase. The genes disrupted were identified, and the gene products were found to be mainly involved with amino acid metabolism (glutamate N-acetyltransferase, 4-hydroxyphenylpyruvate dioxygenase and L-aspartate oxidase) or with recombination (exonuclease RecJ). Each mutant was tested for resistance to stresses, such as oxidative, saline, acidic, heat and UV exposure, showing different responses. Although the mutations obtained were not in genes involved specifically in stationary phase, our results suggest that amino acids metabolism may play an important role in keeping viability during this growth phase.
Invasive bladder cancer: A single‐institution experience with bladder‐sparing approach

Our objective was to assess the efficacy and safety of a selective bladder‐preserving approach by transurethral resection and sequential chemoradiotherapy in patients with muscle‐invasive bladder cancer. From 1989 through 1997, 40 patients with biopsy‐confirmed bladder cancer, clinical stages T2–4NxM0, were treated with induction by aggressive transurethral resection (TUR) and three cycles of methotrexate, cisplatin, and vinblastine (MCV) chemotherapy. Tumor response was evaluated by cystoscopy and biopsy. In complete responders, the treatment was continued by radiotherapy (60 Gy to the bladder and 50 Gy to pelvic lymph nodes). Radical cystectomy was recommended to patients with residual tumor. Clinical complete response rate to TUR and MCV chemotherapy was 70%. The 4‐year actuarial overall survival rate for the whole series was 80.5%. Among 36 patients who completed chemotherapy and radiotherapy, the 4‐year actuarial survival was 84%, with 82.6% surviving with their bladders intact. Freedom from local failure in complete responders to TUR‐chemotherapy was 84%. Multivariate analysis revealed that the extent of initial TUR and status after TUR‐chemotherapy were independent prognostic factors associated with survival and disease‐free survival. This study confirms that the combination of aggressive TUR and sequential chemoradiotherapy with bladder preservation is an alternative treatment option to primary cystectomy for selected patients with invasive bladder carcinoma. Int. J. Cancer (Radiat. Oncol. Invest.) 90, 287–294 (2000). © 2000 Wiley‐Liss, Inc.