Miracle-dz/UniFAR-FTUs huggingface dataset:
Host Identity Protocol Extension Supporting Simultaneous End-Host Mobility

The rapid growth of mobile connected devices has facilitated the explosion of the Mobile Internet, that is IP-based communications involving hosts that frequently change their point of attachment to the Internet. Currently, the Host Identity Protocol (HIP) struggles to maintain the communication in case of 2-party move. This paper describes a HIP extension, based on the enhanced use of Rendezvous server, to provide the support of simultaneous mobility in the HIP layer. The design and the prototype implementation of the solution are presented as well as the framework for preliminary testing.
Surge voltage suppression methods for three-phase to single-phase matrix converter

This paper discusses surge voltage suppression methods in order to design a large capacity three-phase to single-phase matrix converter which is used in AC-DC converters. In order to reduce the surge voltage, the design criteria based on the flow chart of a laminated bus bar (LBB) for the three-phase to single-phase matrix converter is clarified to achieve the lowest stray inductance. As a result, the maximum stray inductance of the LBB for 200-V, 50-kW is achieved to 59 nH in simulation and 58.3 nH in experiment. Besides, when the surge voltage exceeds the tolerance, a snubber capacitor is used in order to limit the surge voltage. In this paper, the design method of the snubber capacitor is also proposed. Concretely, the relationship among snubber capacitance, surge voltage and turn-on loss is derived. As the result, it is confirmed that the surge voltage becomes 231 V when the output current is 310 A by experiment. Thus, the design method of snubber capacitor to suppress the surge voltage is validated.
Coronary segmentation in intravascular optical coherence tomography

Cardiovascular disease (CVD) is a fatal disease of the heart or blood vessels. The greatest number of deaths from CVD is coronary heart disease (CHD). It is characterised by thickening of the arterial vessel wall due to atheromatous plaque which may result in narrowing or even occlusion of arterial lumen. Currently, intravascular optical coherence tomography (IVOCT) has been increasingly used in the clinic for the diagnosis of CHD because it permits high-resolution direct tomographic visualisation of cross-sectional images. With IVOCT techniques, stenosis and restenosis caused by plaques and neointima can be detected and analysed. The first main contribution of the thesis is a technique for the automatic segmentation of the lumen border when the guide-wire artifacts are noticeable. The proposed segmentation technique is capable of eliminating guide-wire artifacts and generating accurate lumen borders from IVOCT sequences. Compared to commercially available systems, the proposed method is robust and accurate. The second main contribution of this thesis is an approach for the stent strut detection that can detect stent struts when their intensity responses are weak. This technique is based on stent strut shadow detection. The innovative aspect of our technique is that, for every detected strut shadow, a-priori probability map is applied to estimate the stent strut position. With the detected stent struts, a stent area can be estimated to analyse the neointimal hyperplasia (NIH) thickness in IVOCT sequences. The thesis also proposes an approach for the neointima segmentation without any information i of the stent but instead with the lumen border. The approach is a combination of a multi-atlas based segmentation approach and a patch-based segmentation approach. With the approach, the neointima label can be obtained by fusing labels from atlases. Compared to other label fusion approaches, a significant increase in segmentation accuracy can be observed.
Limit-cycle navigation method for mobile robot

There are two different approaches to the mobile robot navigation problem including that of robot soccer: deliberative and reactive. In the deliberative approach, a detailed geometric model of the world is used to create a plan that accomplishes the task. This approach suffers from high computational requirements and lacks of robustness in the face of the worldpsilas uncertainty. The reactive approach overcomes the disadvantages of the deliberative approach, but the design that could obtain a desired behavior is difficult. The work reported in this paper overcomes this difficulty by adapting a new navigation method, the limit-cycle navigation method. The defects of the potential field method are also presented. In the proposed method, with the information on the relative position of obstacles, target and robot, the obstacle that affects the robotpsilas path is identified. Then, direction of turn, counter-clockwise or clockwise is decided using the radius of the virtual obstacle. Real experiments ascertain the merits of the proposed method.
Regulation of Sertoli-Germ Cell Adherens Junction Dynamics in the Testis Via the Nitric Oxide Synthase (NOS)/cGMP/Protein Kinase G (PRKG)/β-Catenin (CATNB) Signaling Pathway: An In Vitro and In Vivo Study1

Abstract During spermatogenesis, extensive restructuring of cell junctions takes place in the seminiferous epithelium to facilitate germ cell movement. However, the mechanism that regulates this event remains largely unknown. Recent studies have shown that nitric oxide (NO) likely regulates tight junction (TJ) dynamics in the testis via the cGMP/protein kinase G (cGMP-dependent protein kinase, PRKG) signaling pathway. Due to the proximity of TJ and adherens junctions (AJ) in the testis, in particular at the blood-testis barrier, it is of interest to investigate if NO can affect AJ dynamics. Studies using Sertoli-germ cell cocultures in vitro have shown that the levels of NOS (nitric oxide synthase), cGMP, and PRKG were induced when anchoring junctions were being established. Using an in vivo model in which adult rats were treated with adjudin [a molecule that induces adherens junction disruption, formerly called AF-2364, 1-(2,4-dichlorobenzyl)-IH-indazole-3-carbohydrazide], the event of AJ disruption was also associated with a transient iNOS (inducible nitric oxide synthase, NOS2) induction. Immunohistochemistry has illustrated that NOS2 was intensely accumulated in Sertoli and germ cells in the epithelium during adjudin-induced germ cell loss, with a concomitant accumulation of intracellular cGMP and an induction of PRKG but not cAMP or protein kinase A (cAMP-dependent protein kinase, PRKA). To identify the NOS-mediated downstream signaling partners, coimmunoprecipitation was used to demonstrate that NOS2 and eNOS (endothelial nitric oxide synthase, NOS3) were structurally associated with the N-cadherin (CDH2)/β-catenin (CATNB)/actin complex but not the nectin-3 (poliovirus receptor-related 3, PVRL 3)/afadin (myeloid/lymphoid or mixed lineage-leukemia tranlocation to 4 homolog, MLLT4) nor the integrin β1 (ITB1)-mediated protein complexes, illustrating the spatial vicinity of NOS with selected AJ-protein complexes. Interestingly, CDH2 and CATNB were shown to dissociate from NOS during the adjudin-mediated AJ disruption, implicating the CDH2/CATNB protein complex is the likely downstream target of the NO signaling. Furthermore, PRKG, the downstream signaling protein of NOS, was shown to interact with CATNB in the rat testis. Perhaps the most important of all, pretreatment of testes with KT5823, a specific PRKG inhibitor, can indeed delay the adjudin-induced germ cell loss, further validating NOS/NO regulates Sertoli-germ cell AJ dynamics via the cGMP/PRKG pathway. These results illustrate that the CDH2/CATNB-mediated adhesion function in the testis is regulated, at least in part, via the NOS/cGMP/PRKG/CATNB pathway.
Nanopores fabricated by focused ion beam milling technology

A new approach to fabricating nanopore is presented. It is based on focused ion beam (FIB) sputtering to mill through a silicon nitride (Si3N4) membrane first, then followed by aluminum nitride (AlN) thin film deposition through the milled hole to narrow the pore size. FIB sputtering properties of Si3N4 membranes were investigated in order to achieve high aspect ratio holes through the membrane. The parameters of AlN deposition were optimized so that the final nanopore size can be finely controlled. A nanopore array with 70 nm pore-diameter was made in a Si3N4 membrane by FIB milling technology. The following AlN deposition was able to narrow the nanopores further down to 12 nm pore-diameter.
Experimental Realization of Terahertz Waveguide-Fed Circularly Polarized Double-Fan-Shaped Slot Antenna

A terahertz (THz) waveguide-fed circularly polarized double-fan-shaped slot antenna (DFSSA) based on a silicon micromachining technology is proposed. The antenna is fed by a WR1.9 waveguide. Optimized rotation angle of the double-fan-shaped slot can realize left-hand circular polarization or right-hand circular polarization. The measured axial ratios are lower than 1.5 dB from 490 to 500 GHz. The proposed DFSSA is suitable to be used as feeders in the THz imaging and detection systems.
C LOSE-TO-CLEAN REGULARIZATION RELATES VIRTUAL ADVERSARIAL TRAINING , LADDER NETWORKS AND OTHERS

We propose a regularization framework where we feed an original clean data point and a nearby point through a mapping, which is then penalized by the Euclidian distance between the corresponding outputs. The nearby point may be chosen randomly or adversarially. We relate this framework to many existing regularization methods: It is a stochastic estimate of penalizing the Frobenius norm of the Jacobian of the mapping as in Poggio & Girosi (1990), it generalizes noise regularization (Sietsma & Dow, 1991), and it is a simplification of the canonical regularization term by the ladder networks in Rasmus et al. (2015). We also study the connection to virtual adversarial training (VAT) (Miyato et al., 2016) and show how VAT can be interpreted as penalizing the largest eigenvalue of a Fisher information matrix. Our main contribution is discovering connections between the proposed and existing regularization methods.
Enhancing the needle count in the haystack: serial ultrasonography for low-to-moderate risk adnexal masses.

I is not surprising that pelvic masses are common findings in women, considering that ovaries produce physiologic or functional “masses” every month in ovulating females. Neoplasms are far less common but still prevalent. The real challenge has been in identifying masses that require surgery because they could grow, induce symptoms, or are malignant. This challenge represents the metaphor of the proverbial needle (ovarian cancer) in the haystack (all pelvic masses). The preferred imaging for pelvic masses is ultrasonography, more specifically transvaginal ultrasonography, which is effective at detailing adnexal and uterine anatomy as well as being widely available, multiplanar, and less expensive than computed tomography or magnetic resonance imaging. Because the ovaries are small internal organs and not easily amenable to the clinical detection of morphologic changes, there has been intense interest in assessing the value of ultrasonography in the evaluation of the adnexa. The promise of screening and early detection lies in stage migration, or increasing the proportion of patients being diagnosed at an early, nonmetastatic stage at which most cancers would be curable. However, significant challenges to screening lie in the low prevalence of ovarian cancer (lifetime risk is about 1 in 70), normal morphologic variations, unknown latency period (from preinvasive to invasive disease), cost, risk of unnecessary surgery based on false-positive results, and requirement for serial assessment. Both the Society of Gynecologic Oncology and the American College of Obstetricians and Gynecologists have published guidelines for women with pelvic masses. These guidelines have focused largely on the role of gynecologists and subspecialist gynecologic oncologists in the management of masses based on a number of criteria, including menopausal status, family history, physical findings, and CA 125 levels. These guidelines are helpful but have significant limitations in deciding whether mass removal is necessary; furthermore, the guidelines perform well in predicting advanced-stage ovarian cancer but perform poorly in identifying early-stage disease, especially in premenopausal patients. The conventional approach has been to triage women with pelvic masses to observation or intervention based on ultrasound findings, such that simple cysts were observed and masses with solid elements, septa, or both commonly would be removed. Essentially, this was a binary system, but now three diagnostic categories have emerged with ultrasound evaluation of a mass (benign, indeterminate, and malignant). The most challenging group is those in the indeterminate category with characteristics that raise the concern for malignancy yet fall short of an obvious cancer. See related article on page 210.
Interaction of serum lipoproteins with heparin and phenol.

Addition of phenol to serum induces turbidity which appears to be due chiefly to the beta-lipoproteins. Serum from subjects who have received heparin injections shows decreased phenol turbidity, which appears to be due to formation of a fatty acid-lipoprotein complex, produced in connection with activation of the ‘clearing’ mechanism. Addition of heparin in vitro to mixtures of phenol and serum results in an increased turbidity. The isolated precipitate (by centrifugation) is similar to isolated betalipoprotein, in its ratio of cholesterol to phospholipid. The technique described may furnish a rapid, inexpensive method for determination of beta-lipoproteins in serum, which can be used clinically as a substitute for the expensive, time-consuming isolation by ultracentrifugation. Submitted on March 15, 1957
An evaluation of the Gelman Envirochek® capsule for the simultaneous concentration of Cryptosporidium and Giardia from water

The Gelman Envirochek capsule is a membrane device for the simultaneous concentration of Cryptosporidium oocysts and Giardia cysts from water. Samples are filtered through a Supor® polyethersulphone membrane with a 1 μm absolute pore size. (Oo)cysts are mechanically eluted from the membrane fibre using a wrist action shaker and a non‐ionic detergent and concentrated by centrifugation. The concentrate can be further processed using any separation technique to separate the target organisms from other debris. This method enables multiple samples to be processed within 1 h. Recoveries from seeded tap and source water samples were in excess of 70% for Cryptosporidium and 80% for Giardia.
Compressive sensing based channel estimation for millimeter wave MIMO

Millimeter waves (MMW) are meant for high data rate short range indoor communications. The indoor environment is Doppler sparse, due to slow movement of objects and humans. Thus the Doppler spread becomes negligible. Owing to this fact channel estimation using compressive sensing is used. Conventionally, training symbol based linear channel estimation techniques least squares, minimum mean square error estimation is used in the multiantenna setup. The linear techniques work with the linear combination of multipath symbols and hence computationally complex. Hence in this work, compressive sensing and least square channel estimation techniques are compared with respect to the bit error rate. Comparative analysis indicate compressive sensing achieves the same performance as least square technique with respect to bit error rate however with reduced number of samples. In compressive sensing based channel estimation, Orthogonal Matching Pursuit (OMP) is used as the reconstruction algorithm due to its fast convergence rate and reduced computational complexity.
Managed Objects of Ethernet Passive Optical Networks (EPON)

This document defines a portion of the Management Information Base (MIB) for use with network management protocols in TCP/IP based Internets. In particular, it defines objects for managing interfaces that conform to the Ethernet Passive Optical Networks (EPON) standard as defined in the IEEE Std 802.3ah-2004, which are extended capabilities to the Ethernet like interfaces.
Reducing Asthma Disparities by Addressing Environmental Inequities: A Case Study of Regional Asthma Management and Prevention's Advocacy Efforts

Regional Asthma Management and Prevention describes its collaborative approach to address a social determinant of health—air quality—and the associated inequities that have led to asthma disparities impacting African American and Latino communities in the San Francisco Bay Area. The strategies, aimed at decreasing diesel pollution in disproportionately impacted communities, span the levels of the socioecological model, with an emphasis on policy outcomes. Regional Asthma Management and Prevention describes how this work fits within a larger comprehensive approach to address asthma disparities encompassing several components, ranging from clinical management to environmental protection.
Global ozone–CO correlations from OMI and AIRS: constraints on tropospheric ozone sources

Abstract. We present a global data set of free tropospheric ozone–CO correlations with 2° × 2.5° spatial resolution from the Ozone Monitoring Instrument (OMI) and Atmospheric Infrared Sounder (AIRS) satellite instruments for each season of 2008. OMI and AIRS have near-daily global coverage of ozone and CO respectively and observe coincident scenes with similar vertical sensitivities. The resulting ozone–CO correlations are highly statistically significant (positive or negative) in most regions of the world, and are less noisy than previous satellite-based studies that used sparser data. Comparison with ozone–CO correlations and regression slopes ( d O 3 / d CO) from MOZAIC (Measurements of OZone, water vapour, carbon monoxide and nitrogen oxides by in-service AIrbus airCraft) aircraft profiles shows good general agreement. We interpret the observed ozone–CO correlations with the GEOS (Goddard Earth Observing System)-Chem chemical transport model to infer constraints on ozone sources. Driving GEOS-Chem with different meteorological fields generally shows consistent ozone–CO correlation patterns, except in some tropical regions where the correlations are strongly sensitive to model transport error associated with deep convection. GEOS-Chem reproduces the general structure of the observed ozone–CO correlations and regression slopes, although there are some large regional discrepancies. We examine the model sensitivity of d O 3 / d CO to different ozone sources (combustion, biosphere, stratosphere, and lightning NO x ) by correlating the ozone change from that source to CO from the standard simulation. The model reproduces the observed positive d O 3 / d CO in the extratropical Northern Hemisphere in spring–summer, driven by combustion sources. Stratospheric influence there is also associated with a positive d O 3 / d CO because of the interweaving of stratospheric downwelling with continental outflow. The well-known ozone maximum over the tropical South Atlantic is associated with negative d O 3 / d CO in the observations; this feature is reproduced in GEOS-Chem and supports a dominant contribution from lightning to the ozone maximum. A major model discrepancy is found over the northeastern Pacific in summer–fall where d O 3 / d CO is positive in the observations but negative in the model, for all ozone sources. We suggest that this reflects a model overestimate of lightning at northern midlatitudes combined with an underestimate of the East Asian CO source.
Development of Cardiovascular Quality Indicators for Rheumatoid Arthritis: Results from an International Expert Panel Using a Novel Online Process

Objective. Patients with rheumatoid arthritis (RA) have a high risk of premature cardiovascular disease (CVD). We developed CVD quality indicators (QI) for screening and use in rheumatology clinics. Methods. A systematic review was conducted of the literature on CVD risk reduction in RA and the general population. Based on the best practices identified from this review, a draft set of 12 candidate QI were presented to a Canadian panel of rheumatologists and cardiologists (n = 6) from 3 academic centers to achieve consensus on the QI specifications. The resulting 11 QI were then evaluated by an online modified-Delphi panel of multidisciplinary health professionals and patients (n = 43) to determine their relevance, validity, and feasibility in 3 rounds of online voting and threaded discussion using a modified RAND/University of California, Los Angeles Appropriateness Methodology. Results. Response rates for the online panel were 86%. All 11 QI were rated as highly relevant, valid, and feasible (median rating ≥ 7 on a 1–9 scale), with no significant disagreement. The final QI set addresses the following themes: communication to primary care about increased CV risk in RA; CV risk assessment; defining smoking status and providing cessation counseling; screening and addressing hypertension, dyslipidemia, and diabetes; exercise recommendations; body mass index screening and lifestyle counseling; minimizing corticosteroid use; and communicating to patients at high risk of CVD about the risks/benefits of nonsteroidal antiinflammatory drugs. Conclusion. Eleven QI for CVD care in patients with RA have been developed and are rated as highly relevant, valid, and feasible by an international multidisciplinary panel.
Pandemic H1N1 Influenza Virus in Chilean Commercial Turkeys with Genetic and Serologic Comparisons to U.S. H1N1 Avian Influenza Vaccine Isolates

SUMMARY. Beginning in April 2009, a novel H1N1 influenza virus caused acute respiratory disease in humans, first in Mexico and then around the world. The resulting pandemic influenza A H1N1 2009 (pH1N1) virus was isolated in swine in Canada in June 2009 and later in breeder turkeys in Chile, Canada, and the United States. The pH1N1 virus consists of gene segments of avian, human, and swine influenza origin and has the potential for infection in poultry following exposure to infected humans or swine. We examined the clinical events following the initial outbreak of pH1N1 in turkeys and determined the relatedness of the hemagglutinin (HA) gene segments from the pH1N1 to two H1N1 avian influenza (AI) isolates used in commercial turkey inactivated vaccines. Overall, infection of turkey breeder hens with pH1N1 resulted in ≥50% reduction of egg production over 3–4 weeks. Genetic analysis indicated one H1N1 AI vaccine isolate (A/turkey/North Carolina/17026/1988) contained approximately 92% nucleotide sequence similarity to the pH1N1 virus (A/Mexico/4109/2009); whereas, a more recent AI vaccine isolate (A/swine/North Carolina/00573/2005) contained 75.9% similarity. Comparison of amino acids found at antigenic sites of the HA protein indicated conserved epitopes at the Sa site; however, major differences were found at the Ca2 site between pH1N1 and A/turkey/North Carolina/127026/1988. Hemagglutinin-inhibition (HI) tests were conducted with sera produced in vaccinated turkeys in North Carolina to determine if protection would be conferred using U.S. AI vaccine isolates. HI results indicate positive reactivity (HI titer ≥ 5 log2) against the vaccine viruses over the course of study. However, limited cross-reactivity to the 2009 pH1N1 virus was observed, with positive titers in a limited number of birds (6 out of 20) beginning only after a third vaccination. Taken together, these results demonstrate that turkeys treated with these vaccines would likely not be protected against pH1N1 and current vaccines used in breeder turkeys in the United States against circulating H1N1 viruses should be updated to ensure adequate protection against field exposure.