Miracle-dz/UniFAR-FTUs huggingface dataset:
Comparative Highly Efficient Production of β-glucan by Lasiodiplodia theobromae CCT 3966 and Its Multiscale Characterization

Lasiodiplodan, a (1→6)-β-d-glucan, is an exopolysaccharide with high commercial value and many applications in food, pharmaceuticals, and cosmetics. Current industrial production of β-glucans from crops is mostly by chemical routes generating hazardous and toxic waste. Therefore, alternative sustainable and eco-friendly pathways are highly desirable. Here, we have studied the lasiodiplodan production from sugarcane bagasse (SCB), a major lignocellulosic agricultural residue, by Lasiodiplodia theobromae CCT 3966. Lasiodiplodan accumulated on SCB hydrolysate (carbon source) supplemented with soybean bran or rice bran (nitrogen source) was 16.2 [6.8 × 103 Da] and 22.0 [7.6 × 103 Da] g/L, respectively. Lasiodiplodan showed high purity, low solubility, pseudoplastic behavior and was composed of glucose units. Moreover, the exopolysaccharides were substantially amorphous with moderate thermal stability and similar degradation temperatures. To our knowledge, this is the first report on the highest production of SCB-based lasiodiplodan to date. L. theobromae, as a microbial cell factory, demonstrated the commercial potential for the sustainable production of lasiodiplodan from renewable biomass feedstock.
Skin Cancer Diagnosis using SP-SIFT and Machine Learning

Today information handling is become an integral part of our day-to-day life as it is available in abundance. The information from the internet can be used for various purposes from Security to Healthcare management. It can decrease the load on a human being to handle the data manually. So, to highlight the importance of information handling to the society we choose medical field where images are in abundance on the internet. The analysis of images for decision making in medical perspective can be a boon to the medical field and decrease the work of the doctor and increase his productivity to a new level. The cancer has become a menace these days and has become a major health problem. Computer-aided diagnosis (CAD) systems can be used to provide an insight to the cancer specialist and help him to diagnose the various stages of cancer using images and CAD. So, we thought of designing a CAD system which will help in cancer detection and handling various stages of cancers using cancer images as the backend of our application. We propose to implement it on skin cancer which is an ever-increasing cancer due to pollution and environment changes. To design a successful CAD system for skin cancer, it has to be a combination of image processing and machine learning technologies together. In our proposed system we are going to accumulate a lot of images from various cancer image databases which are available free on the internet and design a cancer database with images put under various stages of skin cancer. After database we will apply SP-SIFT algorithm on it and extract features. This database has to available remotely so we have to maintain this feature set on the cloud. The extracted features will be used to train and get results from SVM and Naïve Bayes. Thus, our results will be divided in three categories melanoma, non-melanoma and benign which define stages of skin cancer. Thus, our system will help and improve the decision making and productivity of a medical practitioner.
Titanium Dioxide as Food Additive

Titanium dioxide is a white metal oxide used in many food categories as food additives to provide a whitening effect. If its use complies with the five specifications including synthesis pathway, crystallographic phase, purity, amount and innocuousness, all other parameters are not defined and were hardly documented. However, in the last 3 years, two studies have deeply characterized food-grade TiO 2 and converged to the fact that the size distribution of food-grade TiO 2 spans over the nanoparticle range (<100 nm) and the surface is not pure TiO 2 but covered by phosphate and eventually silicon species or aluminium species, which modify the surface chemistry of these particles. Until now, this material was considered as safe. However, the toxicological studies later to the last re-evaluation by the European Food Safety Agency reveal some concerns due to the ability of TiO 2 particles to alter the intestinal barrier. This reinforces the idea to go on reinforcing the risk assessment about food-grade TiO 2 .
Review of reduced‐switch multilevel inverters for electric vehicle applications

This paper deals with the detailed review and comparative analysis of latest reduced switch multilevel inverter topologies for electric vehicle applications. The recent trends in reduced‐switch multilevel inverters are discussed. Detailed review of the reduced‐switch multilevel inverter topologies, their merits and demerits, and the comparative analysis based on component count, total harmonic distortion, and efficiency are conducted. This paper gives a detailed review of recent trends in reduced‐switch multilevel inverter topologies for electric vehicle applications. Switching pattern of the topologies is provided for better understanding of the inverter operation. Comparative analysis of the reduced‐switch inverter topologies based on the component count, total harmonic distortion of output voltage, and efficiency is also presented in this paper. Based on the comparative analysis, it is observed that the interleaved nine‐level flying capacitor multilevel inverter topology achieved the lowest output voltage distortion of 1.6%, which is within the acceptable limits of IEEE 519‐2014 standard. It is observed that the three‐level active neutral point clamped multilevel inverter topology achieved the highest working efficiency of 99.4%. This paper discusses the most recent trends in reduced‐switch multilevel inverters. A comprehensive review of the recent publications and a crisp comparative analysis of the different inverter configurations based on component count, harmonic distortion of output voltage, and efficiency are presented in this paper.
SEM-PLS Approach to Green Building

Green buildings refer to buildings that decrease adverse environmental effects and maintain natural resources. They can diminish energy consumption, greenhouse gas emissions, the usage of non-renewable materials, water consumption, and waste generation while improving occupants’ health and well-being. As such, several rating tools and benchmarks have been developed worldwide to assess green building performance (GBP), including the Building Research Establishment Environmental Assessment Method (BREEAM) in the United Kingdom, German Sustainable Building Council (DGNB), Leadership in Energy and Environmental Design (LEED) in the United States and Canada, Comprehensive Assessment System for Built Environment Efficiency (CASBEE) in Japan, Green Star in Australia, Green Mark in Singapore, and Green Building Index in Malaysia. Energy management (EM) during building operation could also improve GBP. One of the best approaches to evaluating the impact of EM on GBP is by using structural equation modelling (SEM). SEM is a commanding statistical method to model testing. One of the most used SEM variance-based approaches is partial least squares (PLS), which can be implemented in the SmartPLS application. PLS-SEM uses path coefficients to determine the strength and significance of the hypothesised relationships between the latent constructs.
Cultural understanding of ‘spiritual well-being’ and ‘psychological well-being’ among Sinhalese Buddhists in Sri Lanka

The influence of culture in conceptualising ‘well-being’ has important implications for human health. Culture influences how individuals experience, conceptualise and reflect on the health behaviour. This study thus explores how Sinhalese Buddhists, who follow Sinhalese medicine in Sri Lanka, conceptualise spiritual and psychological well-being as experienced in their culture. In depth interviews and focus group discussions with twenty-seven participants and empirical observations in four temples revealed that practices that lead to spiritual well-being are embedded in their everyday lives and are conceptualised as internal qualities that facilitate people to interact with the outside world with a proper mode of thought. Psychological well-being is perceived as an ability to achieve whatever that brings happiness to their life. This study thus indicates that although Sinhalese Buddhists in Sri Lanka are less likely to articulate the difference between psychological well-being and spiritual well-being, they are aware of the very existence of spiritual well-being and psychological well-being.
HGF/MET Signalling and DNA Damage Response: Strategies to Conquer Radiotherapy Resistance in Head and Neck Cancer

Head and neck squamous cell carcinomas (HNSCCs) are a heterogeneous group of aggressive malignancies strongly linked with chronic tobacco exposure, excessive alcohol consumption, and infection with high-risk subtypes of Human Papilloma Virus (HPV). Molecularly, HNSCC is classified into HPV-positive and HPV-negative sub-types [1]. Approximately 600,000 new cases are diagnosed annually with 380,000 deaths worldwide [2]. Despite our increased understanding of the viral and genetic mechanisms underlying HNSCC, the 5-year overall survival rate remains around 50% [3]. Radiotherapy (RT), chemotherapy (CT), surgical eradication, or a combination of all modalities are the current therapeutic options but are highly toxic and cause psychological distress and severely compromised quality of life, and hence associated with both symptomology and treatment survivors of this cancer have the second-highest mortality rate of suicide (63.4 per 100,000; [2000-2014]) [4]. The functional and aesthetic features of the head and neck anatomy are factors that make HNSCCs difficult to treat as tumours are located nearby critical anatomical structures which are sensitive to treatment. Radiotherapy (RT), chemotherapy (CT), surgical eradication, or a combination of all modalities are the current therapeutic options. Cetuximab is a monoclonal antibody (mAb) against the epidermal growth factor receptor (EGFR) and has been the only targeted FDA approved targeted therapy for HNSCC until the recent FDA approval of immunotherapy, but, both Cetuximab and immunotherapy clinical efficacy for HNSCC has been limited [5].
Sunlight and orientation in Maharishi Vedic Architecture: a theoretical and empirical study of hemispheric effects

PurposeTo examine whether quality-of-life of a home's occupants varies in northern and southern hemisphere homes when the orientation of the home is always to the eastern sun (as prescribed by Maharishi Vedic Architecture) not orientated differently in northern and southern hemispheres to maximise light (as prescribed by western and Feng Shui architecture design). Design/methodology/approachA theoretical discussion of the use of sunlight and orientation in western, Feng Shui and Vedic approach to architecture, and then a cross-sectional quantitative survey conduced in 14 countries.FindingsThe lived experience of 158 home occupants in Maharishi Vedic Architecture did not vary from northern to southern hemispheres.Originality/valueResearch of this type has never been carried out before on Maharishi Vedic Architecture, except for one other study published in 2020 by these authors which considered the lived experience of home occupants. The amount of research on the basics of Vastu architecture is minimal.
Features Of The "Dark Triad" And Professional Motivation Of University Students

The article discusses the features of negative personality traits ("dark triad": non-clinical narcissism, Machiavellianism and non-clinical psychopathy) in students studying in the direction of special (defectological) education. The article is devoted to the study of the influence of negative personality traits on further professional activity. Short Dark Triad Questionnaire (SD3), designed to diagnose three negative personality traits (machiavellianism, non-clinical narcissism, and non-clinical psychopathy) was used to examine personality traits. Subjective assessment of career success was diagnosed using the author’s questionnaire. The structure of personality disorder indicators was diagnosed by the DSM-5technoque.Second-year students have higher scores on the "non-clinical narcissism" scale. The 2nd year students are more focused on social interaction, open to new knowledge and competence development. In 4th year, the score for 'Machiavellianism' is more pronounced. Research has shown that only narcissism is associated with extraversion, openness and self-regulation. The features of the manifestation of personality traits that are most important for the development of professional motivation were identified.
Combined Geodetic and Seismological Study of the December 2020 Mw = 4.6 Thiva (Central Greece) Shallow Earthquake

On 2 December 2020, a moderate and shallow Mw = 4.6 earthquake occurred in Boeotia (Central Greece) near the city of Thiva. Despite its magnitude, the co-seismic ground deformation field was detectable and measurable by Sentinel-1, ascending and descending, synthetic aperture interferometry radar (InSAR) acquisitions. The closest available GNSS station to the epicenter, located 11 km west, measured no deformation, as expected. We proceeded to the inversion of the deformation source. Moreover, we reassessed seismological data to identify the activated zone, associated with the mainshock and the aftershock sequence. Additionally, we used the rupture plane information from InSAR to better determine the focal mechanism and the centroid location of the mainshock. We observed that the mainshock occurred at a shallower depth and the rupture then expanded downdip, as revealed by the aftershock distribution. Our geodetic inversion modelling indicated the activation of a normal fault with a small left-lateral component, length of 2.0 km, width of 1.7 km, average slip of 0.2 m, a low dip angle of 33°, and a SW dip-direction. The inferred fault top was buried at a depth of ~0.5 km, rooted at a depth of ~1.4 km, with its geodetic centroid buried at 1.0 km. It was aligned with the Kallithea fault. In addition, the dip-up projection of the modeled fault to the surface was located very close (~0.4 km SW) to the mapped (by existing geological observations) trace of the Kallithea fault. The ruptured area was settled in a transition zone. We suggest the installation of at least one GNSS and seismological station near Kallithea; as the activated zone (inferred by the aftershock sequence and InSAR results) could yield events with M ≥ 5.0, according to empirical laws relating to rupture zone dimensions and earthquake magnitude.
COMPARISON OF RESULTS OBTAINED FROM TEMPERATURE MEASUREMENT AND NUMERICAL SIMULATION OF DC PLASMA ARC

The computational method of temperature distribution of free\|burning arc is investigated by using a numerical simulation model, which is based on the local thermodynamic equilibrium. A spectrum temperature diagnostic system of plasma torch based on charge coupled device technology is also presented. Potential, velocities and temperature distribution profile are obtained. These theoretical predictions are in fair agreement with the experimental results.  PACC: 5225; 5265; 5270
Exploring Tourist Behavior in a Reused Heritage Site

This study investigated the relationship among tourists’ perceived sustainability, aesthetic experience, and behavioral intention toward reused heritage buildings by employing stimulus–organism–response theory. There were 354 valid questionnaires collected from the Sputnik Lab in Tainan, Taiwan. A positive correlation was found between tourists’ perception of sustainability and aesthetic experience. When tourists perceived higher aesthetic experience, they also had stronger behavioral intention. Structural equation modeling analysis verified that the aesthetic experience of tourists had mediating effects between perceived sustainability and behavioral intention in the reused heritage space. The reuse of space should be attached significantly to the aesthetic display of space and service so as to promote such scenic spots and increase tourists’ intention to revisit through word of mouth.
A Case Study: Influence of Circuit Impedance on the Performance of Class-E2 Resonant Power Converter for Capacitive Wireless Power Transfer

The evolution of power electronics led to rapid development in wireless charging technology; as a result, a single active switch topology was introduced. The present market utilizes inductive wireless power transfer (IPT); because of the disadvantages of cost, size, and safety concerns, research on wireless power transfer was diverted towards capacitive wireless power transfer (CPT). This paper studies the optimal impedance tracking of the capacitive wireless power transfer system for maximum power transfer. Compared to prior methods developed for maximum power point tracking in power control, this paper proposes a new approach by means of finding impedance characteristics of the CPT system for a certain range of frequencies. Considering the drone battery as an application, a single active switch Class-E2 resonant converter with circular coupling plates is utilized. Impedance characteristics are identified with the help of equations related to the input and resonant impedance. The impedance tracking is laid out for various resonant inductors, and the difference in current peak is observed for each case. Simulations verify and provide additional information on the reactive type. Additionally, hardware tests provide the variation of input current and output voltage for a range of frequencies from 70 kHz to 300 kHz. Efficiency at the optimal impedance points for a resonant inductor with 50 μH and 100 μH are tested and analyzed. It is noted that the efficiency for a resonant inductor with 50 μH is 8% higher compared to the CPT with a 100 μH resonant inductor. Further hardware tests were performed to investigate the impact of frequency and duty cycle variation. Zero-voltage-switching (ZVS) limits have been discussed with respect to both frequency and duty cycle.
Quantum mechanical/molecular mechanical studies of photophysical properties of fluorescent proteins

Light‐responsive proteins are widely employed in bioimaging, for example, fluorescent proteins (FPs), which are comprised of a chromophore centered within a barrel‐shaped protein. FPs exhibit remarkable one‐ and multi‐photon absorption (1PA and MPA, respectively) in addition to their emissive properties. Over the last two decades, many types of quantum mechanical, molecular dynamics, and combined quantum mechanical/molecular‐mechanical (QM/MM) approaches have been employed in the study of the photophysics of FPs. Among the latter, QM/MM approaches have proven to be capable of capturing the strong correlation between FPs' light‐responsive properties and their chromophore–environment interactions. In particular, polarizable embedding QM/MM methods are gaining attention by reason of their outstanding performance in the computation of MPA in FPs. Herein, we discuss the outcomes of some of the investigations performed on the 1PA, MPA, and emissive features of FPs using QM/MM approaches. In addition, critical aspects of the use of QM/MM approaches to study FPs' 1PA and MPA features are described. To those researchers interested in starting to perform MPA computations for FPs using QM/MM methods, this review aims to be a compass to navigate among the relevant available literature.
Design of a Triple-Band Shared-Aperture Antenna With High Figures of Merit

This communication develops a triple-band shared-aperture antenna operating at X/K/Ka-band with high figures of merit such as high aperture reuse efficiency and simple configuration to achieve high gain. The proposed antenna is implemented by integrating a Fabry–Perot (FP) cavity antenna operating at X-band into a dual-band reflectarray antenna enabled by frequency selective surfaces (FSSs). The unit cells (UCs) to form the phase-shifting surfaces for the dual-band reflectarray antenna can offer partial reflectance/transmission abilities at X-band simultaneously, thereby enabling the implementation of an FP cavity antenna. The frequency responses of the proposed antenna are highly independent at X/K/Ka-band, which facilitates the design and optimization. For demonstration, a prototype has been described, fabricated, and measured. The simulated results present 3 dB gain bandwidths of 11.2% (8.4–9.4 GHz), 10.0% (24–26.6 GHz), and 13.3% (35–40 GHz), which are all experimentally verified. The measured results also present a peak gain of 16.8 dBi at 9.0 GHz, 23.8 dBi at 26 GHz, and 26.7 dBi at 38 GHz.
Structural, Kinematic and Geochronological Study of the Main Tianshan Shear Zone in the Borohoro Ranges, NW China

The western segment of the Main Tianshan shear zone (MTSZ) branches into three major dextral strike‐slip shear zones in the Borohoro Ranges, northwestern China. Mylonitic rocks within these zones exhibit vertical foliations, subhorizontal lineations, and dextral kinematics. The microstructures and CPO patterns of calcite and quartz in the tectonites suggest shearing at temperatures of 200°C to 500°C or above. The amount of dextral displacement along the zones is less than 100 km. LA‐ICP‐MS U‐Pb dating of zircons from some pre‐kinematic granites gave ages of 364–325 Ma and 316 Ma, and zircons from a syn‐kinematic leucogranite gave an age of 291 Ma. We propose that dextral shearing along the MTSZ started in the earliest Permian. Our data indicate that collision between the Yili and Junggar plates might have finished before 325 Ma or 316 Ma, with a tectonic transformation from 325 Ma to 300 Ma, resulting in intracontinental transpression from 300 Ma or 291 Ma. We suggest that the formation of the Kazakhstan orocline (KO) took place in two stages, with the early stage of bending driven by convergence related to oblique subduction, and the late stage possibly associated with lateral disarticulation as a result of the dextral strike‐slip shear zones.
Using DPSIR Framework to Determine Secondary School Students’ Conception of Ecological Concepts in the Context of a Wetland Ecosystem

This study investigated the secondary school students’ conception of ecological concepts, based on wetland ecosystem. The guiding question was ‘What is grade 11 students’ conception of ecological concepts in association with Koro-Koro wetland? ’. Thirty-one Grade 11 students were assessed for their understanding, within the Driving-Pressure-State-Impacts-Response (DPSIR) framework. A questionnaire was administered to establish the students’ conceptions. The findings revealed that students’ understanding of their local wetland was relatively better in wetland fauna, and limited in relation to plant diversity, ecosystem energy flow and conceptualization of an ecosystem. Many students could not relate what they learnt in class to their local environment. It is recommended that future studies be directed towards investigating teaching strategies that can effectively enhance students’ scientific understanding of local wetlands.