Miracle-dz/UniFAR-FTUs huggingface dataset:
A Correlational Study of the SEI's Capability Maturity Model and Software Development Performance in DoD Contracts.

Abstract : The Software Engineering Institute's (SEl's) Capability Maturity Model (CMM) is to measure an organization's software development process maturity. The Department of Defense (DoD) has model with the belief that a more mature software development process will result in a more successful software subject. Although there is a growing body of anecdotal evidence supporting this presumed correlation, there is empirical evidence. Thus, the goal of our research was to determine the nature of the correlation, if any, :ware process maturity and software project success, where process maturity is based on a CMM rating and success based on the parameters of cost and schedule. To investigate this correlation we identified software unique aimed CMM rating information on the contractor, collected cost and schedule data from a time frame and schedule of the rating, and interviewed project personnel to collect project context information. Using plots of cost performance versus rating level and nonparametric statistical techniques we found that, within our dataset, a correlation does exist between software development process maturity and project performance. The nature of this appears to be improved cost and schedule performance with higher software process maturity.
Non-Small Cell Lung Cancer Classification from Histopathological Images using Feature Fusion and Deep CNN

Lung cancer is the overgrowth of cells in digestive organs. Identifying different types of lung cancer (squamous cell cancer, large cell carcinoma and adenocarcinoma) from lung histopathological images is outrageous works that shorten the chance of infected with lung cancer in the future. This research propounds an accurate diagnosis scheme using various neural network features and fusion of contourlet transform from lung histopathological image. This lesson has used several pre-train models (Alexnet, ResNet50, and VGG-16) in addition to divers scratch models while the pre-train Resnet50 model works better. The two reduction techniques (Principle Component Analysis (PCA) and Minimum Redundancy Maximum Relevance (MRMR)) have used to classify the type of lung cancer with the extraction of the most significant properties. In Convolution Neural Network (CNN) based lung cancer detection, the reduction approach PCA performs better. This proposed methodology is performed on ordinary datasets and establishes comparative better performance. The accuracy of this paper is 98.5%, sensitivity 96.50, specificity 97.00%, which is more effective than other approaches.
Evaluation of a Fatigue Countermeasures Training Program for Flight Attendants

There is a growing population of employees that work non-traditional hours in around-the-clock operations. Cabin crew/flight attendants are part of this population and work highly variable schedules that include extended duty days, time zone changes, night schedules, and on-demand calls. These schedules conflict with the body’s natural mechanisms for managing sleep and alertness, and often result in fatigue. Fatigue countermeasure training may be necessary for the health, well-being, and safety of workers. The current research evaluated a comprehensive fatigue countermeasure training program for flight attendants using a theoretically grounded taxonomy of training criteria. Alternative evaluation strategies were also utilized to improve traditional pretest– posttest designs and provide convergent evidence of training effectiveness.
Hinder och drivkrafter för energieffektivisering i svensk industri - två fallstudier

Energy efficiency provides a tool for Swedish industry in order to strengthen market positions and increase profits. Energy efficiency measures may not be implemented, despite the fact that investments are cost effective. There are thus barriers and driving forces to energy efficiency. The aim of this work has been to identify barriers and driving forces to energy efficiency in the Swedish industry. Two case studies have been conducted within this work, using in-depth interviews. Case 1 studied energy efficiency within the non energy intensive manufacturing industry. Case 2 studied the use of data in the process industry. The main barriers in Case 1 were: lack of time or other priorities, costs and technical risks related to production disruptions, lack of reliable information regarding energy performance of bought equipment, unsatisfactory measuring (which constitute a barrier when quantifying an energy saving measure), energy related investments are not prioritised, split incentives with outsourcing and Facilities Management, short pay-back criteria and lack of long term strategy. The study also identified a number of driving forces to energy efficiency: a motivated person with power over investment decisions, long term strategy regarding energy efficient technology, knowledge about the site and where site specific energy efficiency measures could be found, environmental values and access to capital. In Case 2 the use of data in pulp mills was studied in an efficiency perspective. These mills collect large amounts of data and the question arises whether these data could be used more efficiently. The main barriers to a more effective use of data were: unreliable data were found to have a negative impact, as analyses and proposed measures also become unreliable. Lacks of time when analyses and proposed measures are handled are closely related to cuts in staff and that production oriented issues are stressed. This barrier implies that an important driving force to energy efficiency are motivated staffs who stress energy efficiency. Other barriers were risk of production disruptions, risk with uncertain future conditions and lack of motivation. Several of the interviewees claimed significant efficiency figures, however no unified conclusion could be drawn. There are both similarities and differences between the two cases. The common barriers were lack of time and costs for production disruptions. Furthermore, a motivated person has been distinguished as a key driving force both in both studies. Other barriers were: lack of long term strategy, technology lock in, low priority of the energy issue and unsatisfactory measuring. Conclusions whether lack of reliable information regarding energy performance of bought equipment is a problem could not be drawn from the two studies as different results were gained.
Inhibitory Effects of Hydrolyzed Oat Bran Proteins on Human LDL Oxidation and Their Bile Acid Binding Capacity

The aim of this project was; 1) to produce and characterize various hydrolyzed proteins from oat brans; 2) determine their antioxidant, metal binding and bile biding capacities as well their ability to inhibit low-density lipoprotein (LDL) oxidation. Medium oat bran samples treated with (cellulase and viscozyme) were digested with five proteases protamex, alcalase, flavourzyme, pepsin and pepsin+pancreatin. VPI-pepsin better scavenged ROO• radicals (496.77±5.83 μM(TE)/g) while VPI-flavourzyme and VPI-pepsin had better quenching for HO• (27.95 ±1.580 and and O2•- (45.31±6.6%) radicals, respectively. VPI-protamex exhibited the best Cu2+ chelating capacity (59.83±1.40%). All hydrolysates protected human LDL against Cu2+ mediated oxidation by reducing the concentration of hydroperoxides from 158.4 to 74.4-97.7 μMH2O2/mg. There was a binding of up to 46.3% for taurodeoxycholate and taurocholate. VPI alcalase proteins displayed the highest activity in the most assay and consequently separated into eleven fractions (F1-F11) (HPLC).
Coplanar Air Launch with Gravity-Turn Launch Trajectories

Abstract : The purpose of this study was to determine the feasibility of launching a vehicle based on the Boeing AirLaunch System in a coplanar, direct to rendezvous trajectory with gravity-turn. The focus of the research was to model the launch trajectory and determine the ability to reach different coplanar orbits. The launch trajectory was modeled using two-dimensional equations of motion and a boundary value problem was posed and solved for the gravity-turn trajectory. Trajectories were then created in an attempt to reach different altitudes through coasting and transfer orbits. Finally a specific orbital altitude was chosen and the trajectories were analyzed to find the most efficient route to the target orbit for fuel and time.
Effects Of Physical Stimuli On Extracellular Matrix Assembly By Chondrocytes And Mesenchymal Stem Cells: Experimental And Finite Element Analyses

Cartilage repair strategies have utilized a wide range of cell types at a similarly wide range of seeding densities, both of which may affect ECM assembly. In this study, we investigated the effects of cell type and seeding density on proteoglycan assembly and the associated mechanical properties of tissue engineered constructs. Bovine and equine articular chondrocytes (AC) and first (P1) and second passage (P2) equine mesenchymal stem cells (MSCs) were encapsulated into alginate disk gels at densities of 1-, 10-, 25-, & 50x10cells/ml for chondrocytes, and 25 x10cells/ml for P1-MSCs and 1-, 10-, & 25 x10cells/ml for P2-MSCs. Glycosaminoglycan content of the gels and surrounding media, as well as the resulting aggregate modulus of the disks was quantified at times up to 6 weeks. GAG accumulation was found to depend on cell type and density, and was observed to change with time. P1-MSCs produced the most total GAG (gel + media). Retention of GAG in gels was highest for bovine AC gels (which were used as a gold standard comparison), with equine MSCs retaining the least GAG. Although P1-MSCs were able to produce the largest amount of GAG, their ability to retain the produced GAG was very limited. This deficiency in retention by MSCs may be related to the lack of accumulation of link protein in MSC seeded gels. This is consistent with the lower amounts of GAG found in stem cell seeded gels by several studies, but also begins to elucidate metabolic patterns of MSCs. Future ∗ Babalola, O.M. and Bonassar, L.J. “Effects of Seeding Density on proteoglycan Assembly by Passaged Mesenchymal Stem Cells,” Accepted for publication in February , 2010 in Cellular and Molecular Bioengineering.
A User’s Guide to Cell-Free Protein Synthesis

Cell-free protein synthesis (CFPS) is a platform technology that provides new opportunities for protein expression, metabolic engineering, therapeutic development, education, and more. The advantages of CFPS over in vivo protein expression include its open system, the elimination of reliance on living cells, and the ability to focus all system energy on production of the protein of interest. Over the last 60 years, the CFPS platform has grown and diversified greatly, and it continues to evolve today. Both new applications and new types of extracts based on a variety of organisms are current areas of development. However, new users interested in CFPS may find it challenging to implement a cell-free platform in their laboratory due to the technical and functional considerations involved in choosing and executing a platform that best suits their needs. Here we hope to reduce this barrier to implementing CFPS by clarifying the similarities and differences amongst cell-free platforms, highlighting the various applications that have been accomplished in each of them, and detailing the main methodological and instrumental requirement for their preparation. Additionally, this review will help to contextualize the landscape of work that has been done using CFPS and showcase the diversity of applications that it enables.
Increase in the maximum lift of an airplane wing due to a sudden increase in its effective angle of attack resulting from a gust

Wind-tunnel tests are described, in which the angle of attack of a wing model was suddenly increased (producing the effect of a vertical gust) and the resulting forces were measured. It was found that the maximum lift coefficient increases in proportion to the rate of increase in the angle of attack. This fact is important for the determination of the gust stresses of airplanes with low wing loading. The results of the calculation of the corrective factor are given for a high-performance glider and a light sport plane of conventional type.
The Role of Optical Coherence Tomography in the Diagnosis of Angle Closed Diseases of the Anterior Chamber. Part 1: Visualization of the Anterior Segment of the Eye

The purpose of this work is to review the literature data on the role of optical coherence tomography in the diagnosis of diseases of the closed angle of the anterior chamber. An analysis of the modern technical devices use — optical coherence tomography of the anterior segment (AS-OST) and models with a frequency-modulated source (Swept Source) is presented. The advent of new imaging technologies such as SS-OCT is advancing the understanding of the pathogenesis of primary angle closure diseases. Visualization of the structures of the anterior segment of the eye is an important part of the strategy aimed at solving the problem of identifying risk factors, diagnosing, monitoring and evaluating the effectiveness of treatment of diseases of primary angle closure. Qualitative and quantitative data analysis based on optical coherence tomography significantly increases the diagnostic accuracy, which undoubtedly plays a key role in the choice of treatment tactics for the closed angle of the anterior chamber. The interpretation of research results should take into account the strengths and weaknesses of traditional methods and newly developed technologies.Conclusion. Optical coherence tomography of the eye’s anterior segment is a standard in modern diagnostics and evaluation of the effectiveness of treatment of diseases of primary angle closure, taking into account pathogenetic mechanisms.
CAPTIVE-TRAJECTORY STORE-SEPARATION SYSTEM OF THE AEDC-PWT 4-FOOT TRANSONIC TUNNEL

Abstract : The captive-trajectory store-separation system of the Aerodynamic Wind Tunnel, Transonic (4T), provides the capability for determining the separation trajectory of a store in the vicinity of the parent aircraft. This system may also be used as a six-degree-of-freedom support for conventional force tests with or without a parent installed, and as a pressure probe or transducer mounting platform for flow field surveys in the vicinity of a model. With the store and parent independently supported in the tunnel, trajectory generation involves measurement of forces and moments acting on the captive store model, converting these to full-scale adding other forces and moments which may be applied to the full-scale store, solving the equations of motion for store acceleration, integrating these equations to find store displacement, converting this movement to model scale, and physically moving the store model along its flight path. This report describes the captive-trajectory store- separation system and its testing capabilities and presents the technique used for trajectory generation.
Writing and Driving: An Assessment of Handwriting Recognition as a Means of Alphanumeric Data Entry in a Driving Context

This paper describes 2 studies conducted within a right-handed, fixed-base driving simulator, both of which investigated the use of handwriting touchpads as a means of entering alphanumeric data while driving. In Study 1, 12 right-handed subjects drove a 10-min. route and on 3 occasions were instructed to enter an address into a navigation system (6 by conventional on-screen keyboard; 6 using a prototype handwriting recognition system) with their non-preferred left hand. There was evidence that time taken to enter a destination while driving was reduced and driving performance was improved when subjects used handwriting vs. the on-screen keyboard. In addition, subjects strongly preferred the handwriting system. Study 2 focused on the impact of the location of a handwriting touchpad. 14 right-handed subjects drove 2 routes, each of about 10 min. duration, and at pre-determined points were instructed to use either their non-preferred (left) or preferred (right) hand to write a range of single characters. In this study, there was evidence that using the non-preferred hand for data entry was more difficult and the quality of handwriting poorer, as compared with use of the right hand. With respect to driving performance, speed variability was found to be greater when drivers used their left as compared to their right hand. It was concluded that handwriting touchpads offer some advantages over conventional alphanumeric data entry systems in cars, but should be capable of being placed in a range of positions in the vehicle to suit the handedness/comfort requirements of the driver.
Micro-machined membrane deformable mirrors for cryogenic adaptive optics

In this Thesis, the suitability of 37 actuator Micro-machined membrane deformable mirrors (MMDM) for adaptive optics at cryogenic temperatures is evaluated. A method is described to safely cool MMDMs to 78K. The initial surface figures of three MMDMs are examined using a Zygo phase shifting interferometer to evaluate the effects of both evacuating and cooling the MMDM. The cooling process increases the aberrations inherent in the MMDMs' membranes. One of the MMDMs evaluated is found to have intrinsic aberrations sufficiently small to leave substantial dynamic range free for wavefront correction; the available range is determined by the beam diameter being corrected. The influence functions of the actuators of the MMDMs are then examined; the cooling process leaves the form of the influence functions unchanged, but reduces the magnitude by 20%. The dynamic response is evaluated for MMDMs up to a driving frequency of 500Hz. Evacuation, which removes air damping, has no effect on the dynamic response. Cooling the MMDMs shows a high frequency ringing at a frequency of 2kHz, irrespective of MMDM driving frequency. This effect is very small for the MMDM with the superior initial surface figure, which can be considered to be suitable for operation in a cryogenic adaptive optics system. This was the first demonstration of an adaptive optical element functioning at cryogenic temperatures. A simulation is developed to demonstrate that an adaptive optics system could be constructed utilising a MMDM and a curvature sensor that corrects wavefronts without a wavefront reconstruction step. This system gives good correction for defocus, coma and spherical aberration, with reasonable correction for astigmatism. Potential avenues for future exploration are discussed, notably the prospect of optimising the design of MMDMs for cryogenic operation.
Quantifying public transport reliability from a passenger perspective by using operational data

Urban public transport has been developed during the last years, trying to achieve its growth to provide better social, economic and environmental benefits. The reliability of public transport is a key determinant when considering the quality of the service. From a passengers’ perspective, service reliability it’s a key factor to attract and retain passengers in the long term. Since public transport is able to improve and ensure accessibility and livability of cities and since public transport might create a reduction of the negative impacts of increased car mobility, an increase in quality of public transport is necessary. Reliability has been defined from different aspects of bus services in many studies. Buffer time indicators have been the preferred ones to analyze reliability since they reflect passenger-focused attributes. However, passenger’s perception is lost from the time when it takes into account the total travel time. Using AVL system data (automatic vehicle location) and GoCard (automated fare collection) data, which provides the progress of each vehicle as well as passenger loadings, has enabled the analysis of service reliability from the passenger’s perception. All these data was analyzed to make an accurate assessment of the service reliability, comparing different measures. The selected measure was used to investigate the reliability performance for some of the Brisbane bus operations.
Performance in Product Development - The Case of Complex Products

This research addresses the concept of performance in the development of complex products. More specifically, its aim is to study how performance is perceived and measured within large global companies, and how performance measurement systems can be designed in a systematic way. The exploratory results regard how performance is currently perceived and measured. It is argued that performance measurements are focused on the later stages of the development of complex products, thus making it difficult to perform changes during the development. The focus is on lagging rather than leading indicators of performance, hence it is concluded that focus is on reporting the result rather than the causes of the result. In line with these findings is the weak link between what managers perceive as success factors and what is measured, the perception of performance being influenced by what is measured, rather than the reverse. The prescriptive results focus on the development of models and frameworks to be used during the development of complex products. A general method for developing performance indicators is presented. The concept of Products in Development is proposed, this making it possible to monitor how value is created during the development of a product. Both these models aim at complementing the currently used performance measurement system in order to support effective and efficient development of complex products. The method used in this research is mainly focused around the collection of qualitative data through a focused group interview, multiple case studies,and industrial reference-group seminars. A survey has also been used to complement the qualitative with quantitative data. The use of various research methods has made it possible to triangulate the data, thus strengthening the validity of the findings.
Characterization of a Novel Pathogenic Mutation Causing Mitochondrial Neurogastrointestinal Encephalopathy

Background Mitochondrial neurogastrointestinal encephalopathy (MNGIE) is a rare autosomal recessive disorder caused by mutations in TYMP gene, encoding nuclear thymidine phosphorylase (TP). MNGIE mainly presents with gastrointestinal symptoms and is mostly misdiagnosed in many patients as malabsorption syndrome, inflammatory bowel disease, anorexia nervosa, and intestinal pseudo-obstruction. Up to date, more than 80 pathogenic and likely pathogenic mutations associated with the disease have been reported in patients from a wide range of ethnicities. The objective of this study was to investigate the underlying genetic abnormalities in a 25-year-old woman affected with MNGIE. Case Presentation The patient was a 25-year-old female referred to our center with the chief complaint of severe abdominal pain and diarrhea for two years that had worsened from two months prior to admission. The clinical and para-clinical findings were in favor of mitochondrial neurogastrointestinal encephalopathy syndrome. Subsequent genetic studies revealed a novel, private, homozygous nonsense mutation in TYMP gene (c. 1013 C>A, p.S338X). Sanger sequencing confirmed the new mutation in the proband. Multiple sequence alignment showed high conservation of amino acids of this protein across different species. Conclusion The detected new nonsense mutation in the TYMP gene would be very important for genetic counseling and subsequent early diagnosis and initiation of proper therapy. This novel pathogenic variant would help us establish future genotype-phenotype correlations and identify different pathways related to this disorder.