Miracle-dz/UniFAR-FTUs huggingface dataset:
Direct Load Voltage Control for Electrolytic Capacitorless Wireless Power Transfer System Without DC/DC Converter

This article presents a new direct load voltage control method for electrolytic capacitorless wireless power transfer (WPT) system without dc/dc converter. In specific, the three-phase low-frequency ac to the high-frequency ac (HFac) converter is employed into the electrolytic capacitorless WPT system by using the bidirectional power switches. The HFac voltage is directly generated on the transmitting tank without using the electrolytic capacitor. Furthermore, in order to realize the discretionary and accurate load voltage control without dc/dc converter, the nine voltage vectors, including six effective voltage vectors and three zero voltage vectors, are selectively exported for the transmitting tank with different duty cycles. In addition, the unity power factor correction and direct load voltage control are both achieved only by transmitting side control. Meanwhile, theoretical analysis of double series-compensated transmitting network and duty cycles under resonant frequency calculation in microchip are demonstrated in detail. Finally, both simulation and experimental results are provided to verify the feasibility and correctness of the proposed system, which operates at 85 kHz with 90% efficiency and about 9% total harmonic distortion.
Multiple Selection Signatures in Farmed Atlantic Salmon Adapted to Different Environments Across Hemispheres

Domestication of Atlantic salmon started approximately forty years ago, using both artificial and natural selection strategies. Such selection methods are likely to have imposed distinctive selection signatures on the salmon genome. Therefore, identifying differences in selection signatures may give insights into the mechanism of selection and candidate genes of biological and productive interest. Here, we used two complementary haplotype-based statistics, the within-population integrated Haplotype Score test (|iHS|) and the cross-population Extended Haplotype Homozygosity test (XP-EHH) to compare selection signatures in four populations of Atlantic salmon with a common genetic origin. Using |iHS| we found 24, 14, 16 and 26 genomic regions under selection in Pop-A, Pop-B, Pop-C, and Pop-D, respectively. While using the XP-EHH test we identified 27, 25 and 15 potential selection regions in Pop-A/Pop-B, Pop-A/Pop-C and Pop-A/Pop-D, respectively. These genomic regions harbor important genes such igf1r and sh3rf1 which have been associated with growth related traits in other species. Our results contribute to the detection of candidate genes of interest and help to understand the evolutionary and biological mechanisms for controlling complex traits under selection in Atlantic salmon.
Cognitive Outcomes in Children With Temporal Lobe Epilepsy: Predictors of Academic Attainment

Objectives: Children with temporal lobe epilepsy (TLE) are at a significant risk of cognitive disability and academic underachievement. Where medicines have proven ineffective for seizure management, surgical intervention has proven to be valuable treatment; nevertheless, the long-term cognitive and academic outcomes for this group of children are unclear. Method: Clinical data on 72 children who underwent surgical resection for unilateral TLE were reviewed at around 12-months post-surgery. Pre- versus post-surgery cognitive and achievement assessments were compared to investigate outcomes and the contributions of demographic and epilepsy-related variables. Results: The findings suggest overall modest improvements in test scores, but with some areas of greater change, including decline in some domains. The picture is dominated, however, by substantial individual variability. Conclusions: Epilepsy surgery for TLE in childhood does not, in general, have a significant deleterious or positive effect on cognition or academic achievement, in the short-medium term. Marked individual variation is the norm. Research and clinical implications, particularly a need for longitudinal studies, are discussed.
Arsenite oxidation by a Hydrogenobaculum sp. isolated from Yellowstone National Park

A novel Hydrogenobaculum sp. was isolated from an acid-sulfate-chloride geothermal spring in Yellowstone National Park (YNP)5 WY5 USA that had previously been shown to contain microbial populations engaged in arsenite oxidation. Acid-sulfatechloride thermal springs are a prominent spring type in the Yellowstone geothermal complex and provide unique habitats to study chemolithotrophy where iron, sulfur, arsenic, and perhaps hydrogen gas represent the predominant potential electron donors for generating energy. The organism (designated HS 5) is an obligate microaerophilic chemolithoautotroph that grows exclusively on hydrogen gas as an electron donor. The optimum temperature and pH for HS5 are 55-60°C and 3.0, respectively, and the 16S rDNA sequence of HSS is 98% identical to Hydrogenobaculum acidophilum. Whole cells of HSS displayed Michaelis-Menten type kinetics when oxidizing arsenite, with an estimated Km of BOpM arsenite and a Vmax of 1.47 pM arsenite oxidized / min. (for 1.0 x IO6 cells per ml). The native habitat of HSS contains large amounts of ferric iron in the stream sediments and high concentrations of aqueous hydrogen sulfide, with concentrations of the latter negatively correlated with arsenite oxidation in the spring. Both chemical species were examined for their contribution to, or influence of, overall (i.e. biotic plus abiotic) stream arsenic redox activity by comparing their effects with arsenite oxidation activities of pure cultures of HS 5. The abiotic oxidation of arsenite by ferric iron occurred at significantly slower rates than that observed with HS 5, and aqueous sulfide appeared to inhibit the putative arsenite oxidase of HS 5. The abiotic reduction of arsenate via aqueous sulfide was negligible under the experimental conditions utilized. The isolation and characterization of this novel Hydrogenobaculum sp. initiates the process of characterizing the microbial populations inhabiting acidsulfate-chloride thermal springs in YNP, and contributes fundamental information to enhance the general understanding of the biogeochemistry that shapes the YNP geothermal landscape.
Translation and validation of an extended German version of ID Migraine™ as a migraine screening tool

Background and purpose: Diagnosing a patient with headache as a migraineur is critical for state-of-the-art migraine management. Screening tools are imperative means to improve the diagnostic yield in the primary care settings and specialized clinics. This study aims to translate and assess the diagnostic accuracy of a German version of the ID Migraine™ as a widely used and efficient screening instrument. Methods: The Functional Assessment of Chronic Illness Therapy translation methodology was used to translate the original three-item ID Migraine™, including a fourth question for aura, from the English language into the German language. Diagnostic accuracy of the German ID Migraine™ and predictors of false screening results were assessed among patients presenting to a headache outpatient clinic of a tertiary care center in Germany over a 6-month period. Results: The translation procedure yielded a harmonized German ID Migraine™ and its diagnostic accuracy was assessed in 105 patients (80 female, 46.5 ± 17.2 years of age), including 79 patients (75.2%) with migraine. The three-item German ID Migraine™ provides a sensitivity of 99%, specificity of 68%, and positive and negative predictive values of 90% and 95%, respectively, using a cutoff of ≥2. Positive and negative predictive values in a general headache population are estimated to be 74% and 98%, respectively. The aura question identified 18 out of 20 migraineurs with aura. Conclusions: The German ID Migraine™ is an accurate screening tool for migraine even in a challenging population of a specialized outpatient clinic. Its diagnostic accuracy indicates a potential utility for screening in primary health care.
The effects of 4-vinylcyclohexene diepoxide on the testes of dogs

This study was aimed at investigating the effects of 4-vinylcyclohexene diepoxide (VCD) on testicular tissue in dogs. For this purpose, 30 mongrel male dogs were used and allocated to 5 groups randomly. The first group (n = 6), used as the control, was administered sesame oil by the intraperitoneal route (i/p). The VCD was administered i/p at doses of 80, 160, 240, 320 mg/kg to the second, third, fourth and the fifth groups (n = 6), respectively, once a day for 8 days. The dogs were surgically castrated on the day after the last VCD injection. The testes were removed immediately and fixed in 10% bouine solution. The testes were subjected to routine tissue processing and examined to determine the testicular damage in each testis. When compared to the control group, it was seen that the seminiferous tubule damage increased significantly in the treatment groups. Malondialdehyde levels reached the highest level in the fifth group, while superoxide dismutase, catalase, glutathione peroxidase activity and glutathione levels were higher in the control group (P<0.0001). Nosignificant difference was detected when all the groups were compared with respect to AST, ALT and GGT activities before and after the treatment (P>0.05). Our results showed that VCD may contribute to the sterilization of male dogs.
Erectile dysfunction and mood disorders in patients undergoing cardiac rehabilitation

Introduction. Mood disorders, a predominant symptom of depression, are correlated with the risk of cardiovascular disease (CVd) development and unfavourable course. Anxiety that accompanies CVd is concurrently its cause, consequence, and debilitating factor. There is also a correlation between CVd and erectile dysfunction (Ed). The purpose of this study was to investigate the relationship between mood disorders and Ed in men undergoing cardiac rehabilitation and determine the role of diabetes and other risk factors in both health problems. Methods. The study involved 69 men aged 32–79 admitted to cardiac rehabilitation procedure. Beck depression inventory served to measure mood disorders, and international index of Erectile Function 5 to establish sexual dysfunction. A survey pertaining social, demographic, and clinical data was conducted among the participants. Results. overall, 85.5% of the participants were overweight or obese. over half of them suffered from hypertension or lipid disorders. About a third had diabetes, 77% smoked cigarettes. Mood disorders were found in 5 men, Ed among 74% of the participants. There was no statistically significant correlation between mood disorders and diabetes, smoking, or excess body mass. Ed prevalence showed no correlation with overweight or mood disorders. The only statistically significant risk factor for Ed was diabetes. Conclusions. The results do not reveal a connection between mood disorders and Ed in the studied sample. it is impossible to measure shared risk factors for both disorders in a group with only 5 people presenting depression symptoms. diabetes significantly influences Ed prevalence among men with coronary artery disease.
Evaluation of dry matter production and yield in early-sown wheat using near-isogenic lines for the vernalization locus Vrn-D1

ABSTRACT Wheat (Triticum aestivum L.) grain yield is predicted to decrease in the future because of an increase in air temperature globally. To clarify the effects of the vernalization response gene in wheat to warmer winters, we compared dry matter production and grain yield between spring wheat ‘Asakazekomugi’ and its winter-type near-isogenic line (NIL) carrying different alleles of the vernalization response gene Vrn-D1 under early-, standard-, and late-sowing conditions. Under early-sowing conditions, dry matter production of the NIL carrying the winter allele of Vrn-D1, named Asa (Vrn-D1b), exceeded that of ‘Asakazekomugi’ from mid-March (after stem elongation in Asa (Vrn-D1b)) when the temperatures rose. Tiller number and leaf area index under early-sowing conditions were consistently higher in Asa (Vrn-D1b) than in ‘Asakazekomugi’ from mid-March onward. It was suggested that the early-sown ‘Asakazekomugi’ could not effectively absorb solar radiation to produce dry matter because of the acceleration of stem elongation caused by the Vrn-D1 gene during the cold season. The grain yield of Asa (Vrn-D1b) with early sowing was higher than with standard sowing. In contrast, the grain yield of ‘Asakazekomugi’ was lower in the early-sown crop than in the crop sown at the standard date. These results suggested that the higher grain yield of Asa (Vrn-D1b) than that of ‘Asakazekomugi’ under early-sown conditions could be due to Asa (Vrn-D1b) maintaining high dry matter production after the jointing stage by suppressing acceleration of growth caused by warm conditions after sowing. Abbreviations CGR: crop growth rate; HI: harvest index; LAI: leaf area index; NIL: near-isogenic line; SNP: single-nucleotide polymorphism
A Combination of Transmission Line Models as Design Instruments for Electromagnetically Coupled Microstrip Patch Antennas in the 2.45 GHz ISM Band

This communication presents an analytical framework that combines transmission line models for the design of electromagnetically coupled microstrip patch antennas for the 2.45 GHz industrial, scientific, and medical band. It provides initial values for all dimensions of the antenna, with measured resonance frequency errors below 6%. The initial design is optimized in two subsequent phases to center the resonance frequency and to increase the impedance bandwidth (BW), obtaining measured resonance frequency errors below 0.6% and BW enhancements of more than 1.2 times the original ones, respectively. The model has been validated with antenna prototypes based on rigid and textile materials, exhibiting excellent free-space measured BW of 4% and 5.12%, maximal measured gains of 4.28 and 7.33 dBi, and radiation efficiencies of 63.4% and 71.8%, respectively. Moreover, very stable on-body performance is obtained, with minimal frequency detuning when deploying the textile antenna on the human body. The measured maximum on-body gain for the textile antenna equals 5.5 dBi, with a simulated specific absorption rate of 0.323 W/kg at 2.45 GHz.
PREDICTING MAJOR ADVERSE CARDIAC EVENTS (MACE) ONE YEAR AFTER PERCUTANEOUS CORONARY INTERVENTION (PCI) PROCEDURE: DEVELOPMENT AND VALIDATION OF MODELS.

Predictive analytics assist and improve healthcare management of patients as follow-ups to percutaneous coronary intervention (PCI) procedure. This research aimed to construct, validate, and measure performance of three predictive models in predicting major adverse cardiac events (MACE) within one year after PCI. This study utilized data of 10511 patients who underwent PCI at the National Heart Institute (IJN) between 2008 and 2012. The data mainly consisted of information on patientÂs demographic, health status before and during the PCI procedure, and MACE outcome within one year after the procedure. The data was split into development and validation datasets. After variable selection process, predictive models based on logistic regression, artificial neural network (ANN), and decision tree were developed using the development data set. Each model then validated using the validation dataset. Performance of the models were measured using Matthews correlation coefficient (MCC). MACE occurred amongst 12.9% patients during 1-year follow-up. Fifteen predictors were identified to significantly associated with 1-year MACE. ANN model gave the best performance, followed by logistic regression and decision tree.ANN is a reliable model to predict MACE case after PCI procedure. The findings enlighten clinicians and patients to plan better management after PCI.
Rain-Type Classification From Microwave Satellite Observations Using Deep Neural Network Segmentation

The understanding of different characteristics of the stratiform and convective system is important for meteorological research, including precipitation retrievals from satellite observations, precipitation parameterization in numerical prediction models, and precipitation climatology. In this study, the possibility of discriminating rain types using deep learning techniques is examined using satellite microwave observation data. Herein, we build two types of deep neural networks for rain type classification, i.e., U-net (RTC-U-net) and fully connected neural network (RTC-fcNN). Experiments are performed with the data obtained from two sensors onboard the global precipitation measurement (GPM) satellite. The brightness temperatures observed from the GPM microwave imager (GMI) are used as input features, whereas rain types retrieved by dual-frequency precipitation radar (DPR) are used as labels. We generated the merged 40- $\times $ -40 pixel data for training and testing the data set by cropping the GMI observed fields overlapping the DPR observations. Overall, the proposed RTC-U-net and RTC-fcNN effectively classify four rain types, i.e., no-rain, stratiform, convective, and others. The total accuracy for the four rain types is 0.95, and the weighted mean of precision, recall, and f-score for stratiform and convective are 0.76, 0.68, and 0.71, respectively. Results show that the proposed techniques can extract the characteristics of each rain type from the data itself. To the best of our knowledge, this study is the first to apply a segmentation method with U-net for rain type classification.
Molecular characterisation of rice tungro bacilliform virus isolated from Bario, Sarawak

Rice tungro disease is one of the most damaging and destructive diseases of rice in South and Southeast Asia. The disease is caused by the co-infection of two viruses, the Rice tungro bacilliform virus (RTBV) and Rice tungro spherical virus (RTSV). The symptoms and severity of the disease depend on these two viral agents, if rice is coinfected by both viruses, it will show the typical severe symptoms of yellow-orange leaf discoloration, plant stunting and reduced in yield. On the other hand, if rice is infected only with RTBV, it shows milder symptoms and in contrast, rice plants will show no symptoms if they are infected only with RTSV. The disease had been detected in Malaysia since the 1930s. However, the first incursion of the disease was only reported in Sarawak in 2012. Since the disease was not seen in the Sarawak until recently, very little information on local virus isolate is available. This study was conducted to obtain and record the nucleotide sequence of partial coat protein gene of two primary isolates of RTBV collected from Bario, Sarawak in 2012 and 2013. Methodology and results: Based on the phylogenetic analysis, the isolates cluster with the Southeast Asia group with sequence identity at nucleotide and amino acid level of 91.1 to 95.1% and 98.6 to 99.5% respectively. Conclusion, significance and impact of study: This study provide the first genetic information on RTBV isolates from Sarawak. This data is important for future reference of the virus variants and diversity for epidemiological and diagnosis purposes.
Robust Nonstationary Local Slope Estimation

The plane-wave destruction (PWD) method has been a widely used local slope estimation method in the seismic community. It is based on the discretization of the plane-wave partial differential equation (PDE) and the linearization of the PDE with respect to the local slope. Solving the linearized inverse problem for the slope perturbation is equivalent to solving a smoothness constrained optimization based on a shaping regularization method. The smoothness constraint in the shaping regularization is important in that it not only controls the stability and smoothness of the solution, i.e., slope perturbation, but also affects the accuracy and resolution of the solution. The traditional PWD algorithm is not easy to compromise between the smoothness and resolution of the estimated local slope because it uses a stationary triangle smoothing operator as the shaping operator. Here, we propose to improve the robustness of the PWD algorithm by introducing a nonstationary triangle smoothing operator into the shaping regularization framework in order to adaptively constrain the solution according to the local signal reliability. The smoothing is weak in areas with a higher probability of signals and is strong in areas with a higher likelihood of noise. The smoothing radius can be adaptively estimated based on an optimization model, which is solved by a line-search method. The proposed new slope estimation method is referred to as a nonstationary method compared with the traditional stationary one. The effectiveness and benefits of the new slope estimation method are validated via several synthetic and field data examples.
A 22-to-47 GHz 2-Stage LNA With 22.2 dB Peak Gain by Using Coupled L-Type Interstage Matching Inductors

This article presents a 22–47 GHz wideband low-noise amplifier (LNA) with coupled L-type interstage matching inductors. The coupled inductors extend the bandwidth of LNA by moving zeros to lower frequencies to cancel the effect of poles. Meanwhile, asymmetric L-type inductors with different inductances can be designed separately to achieve better gain flatness. In addition, the quality factor of coupled inductors is also slightly improved without significantly changing their inductance. The LNA is fabricated in a 0.13- $\mu \text{m}$ SiGe BiCMOS technology, and it occupies a core area of 0.13 mm2. The LNA achieves a peak gain of 22.2 dB with the 3dB bandwidth of 22–47 GHz (fractional bandwidth up to 72.5%). The measured NF varies between 3.0 and 4.3 dB from 22 to 47 GHz. The measured input 1-dB gain compression point is stable from −23.9 to −22.6 dBm in the entire 3-dB gain bandwidth. The chip consumes a total power of 9.5 mW from a 1.2 V supply.
Cancer insights through macropinocytosis: a role for sorting nexins?

Macropinocytosis is an actin-driven endocytic process, whereby membrane ruffles fold back onto the plasma membrane to form large (> 0.2 µm in diameter) endocytic organelles called macropinosomes (Swanson & Watts, 1995). The rapid and large fluid-carrying capacity of macropinosomes is central to their role in the immune response, possessing great potential for antigen sampling from the environment as the amount of material internalized greatly exceeds that of other endocytic pathways (Norbury, 2006). Studies of oncogenic signaling and cellular responses to growth factors have also implicated macropino-cytosis in the molecular mechanisms of cancer and tumorigenesis. Treatment with Epidermal Growth Factor (EGF), Platelet-Derived Growth Factor (PDGF) and Hepatocyte Growth Factor/Scatter Factor (HGF/SF) - ligands associated with uncontrolled cell proliferation in cancerous tissue - have all been shown to rapidly increase the rate of macropinosome formation and fluid-phase uptake (Kerr & Teasdale, 2009). Cells overexpressing oncogenes have been shown to exhibit elevated levels of macropinocytosis, as well as accelerated spontaneous motility in wound healing assays (Platek