Miracle-dz/UniFAR-FTUs huggingface dataset:
Measuring Medical Student Anxiety Toward the Male Genitourinary Rectal Examination

Background: Medical educators agree that the male genitourinary rectal (GUR) exam, is the most anxiety-evoking intimate examination, and can evoke a state of anxiety for medical students that adversely affects their learning and performance of the examination. Further, researchers have demonstrated that medical students with high anxiety when learning to perform the male GUR exam may experience long-term, adverse effects that influence their success in performing the examination as practicing physicians. The development of a rating scale used to measure medical student anxiety toward the male GUR exam and an in-depth evaluation of validity evidence is required before extensive research in the area can be performed. Methods: A novel rating scale used to measure medical student anxiety toward the make GUR exam (A-GUR) was developed. A total of 468 student participants were recruited from two Midwestern urban medical universities during their institution’s clinical GUR examination programs. From University A, a state funded school, 169 second-year students [male = 88 (48.3%), female = 96 (51.7%)] participated. From University B, a private school, a combined total of 337 first and second-year medical students [male = 182 (54.0%), female = 155 (46.0%)] participated. Prior to performing the exam on a “patient,” students completed the 5- point, 47-item A-GUR scale. The Many-Facet Rasch measurement approach was used to evaluate evidence relevant to content, substantive, structural, generalizability, and external aspects of validity. Results: Findings of this study offer validity evidence that supports content and substantive and external aspects of validity, but evidence relevant to structural aspect of validity was inconsistent. Although evidence supported the Rasch model’s assumptions of mononotonicity and local independence, results of principal component analysis and evaluation of AIC and BIC did not support unidimensionality. Evidence also did not fully support generalizability, and suggested that ethnicity and gender may contribute to findings. Conclusion: Although findings of this study offered some forms of validity evidence, the impact of gender and ethnicity have on medical student anxiety should be researched further before making inferences about the measures from the instruments with confidence.
Characterizing the proteome of complex biological samples by LC-MS/MS-based shotgun proteomic analysis depends on a number of critical factors, including effective protein solubilization and denaturation, thorough protein to peptide digestion, and efficient recovery of tryptic peptides from

The ionic detergent sodium deoxycholate (SDC) is compatible with in-solution tryptic digestion and LC-MS/MS-based shotgun proteomics by virtue of being easy to separate from the peptide products via precipitation in acidic buffers. However, it remains unclear whether unique human peptides co-precipitate with SDC during acid treatment of complex biological samples. In this study, we demonstrate for the first time that a large quantity of unique peptides in human blood plasma can be co-precipitated with SDC using an optimized sample preparation method prior to shotgun proteomic analysis. We show that the plasma peptides co-precipitated with SDC can be successfully recovered using a sequential re-solubilization and precipitation procedure, and that this approach is particularly efficient at the extraction of long peptides. Recovery of peptides from the SDC pellet dramatically increased overall proteome coverage (>60%), thereby improving the identification of low abundance proteins and enhancing the identification of protein components of membrane-bound organelles. In addition, when we analyzed the physiochemical properties of the co-precipitated peptides, we observed that SDC-based sample preparation improved the identification of hydrophilic/hydrophobic proteins that would otherwise be lost upon discarding the pellet. These data demonstrate that the optimized SDC protocol is superior to sodium dodecyl sulfate (SDS)/urea treatment for identifying plasma biomarkers by shotgun proteomics.
Influence of intellectual stimulation on employee engagement in parastatals in the energy sector in Kenya

Employee engagement continues to pose a challenge to parastatals. Consequently, governments have adopted the transformational leadership style as an effective method of enhancing employee engagement. Nevertheless, it is still unknown whether the establishment of transformational leadership dimensions has boosted employee engagement in the Kenyan energy sector parastatals. The objective of this study was to investigate the influence of intellectual stimulation on employee engagement in parastatals in the energy sector in Kenya. Also, the study sought to determine the moderating influence of employee motivation on the relationship between intellectual stimulation and employee engagement. This study targeted the 10 parastatals within the energy sector in Kenya with a population of 315 middle-level managers. The study adopted a positivist research philosophy to examine the influence on intellectual stimulation on employee engagement and data was collected using structured questionnaires. A correlational research design was conducted with the purpose of determining the strength of the relationship between parameters of intellectual stimulation and employee engagement.The findings showed that employee engagement has a statistical significant relationship with creativity and innovation, r(166) = 0.540, p < 0.01; job design, r(166) = 0.452, p < 0.01 and employee involvement, r(166) = 0.512, p < 0.01. Multiple linear regression analysis revealed that employee motivation positively and significantly moderates the relationship between intellectual stimulation and employee engagement, R2= . 409, F(2, 159) = 55.115, p <. 05; β = 0.259, p <. 01. The study concluded that creativity and innovation, job design, employee involvement, and employee motivation positively enhance employee engagement.
Nutritional status of rural primary school children aged 7 to 12 years old in district of Pitas, Sabah measured using anthropometry, dietary habits and household income.

Nutritional status evaluation of primary school children aged 7 - 12 years old was carried out in Pitas, Sabah. Three primary school were selected for the study involving 360 (180 boys, 180 girls) pupils in Standard 1 until Standard 6. Focus in this study was measurement of weight and height and Body Mass Index (BMI) calculation, measurements were compared with NCHS/ CDC 2000 growth chart. Parent-assisted questionnaires were used to study demographic, medical history, dietary habits and food frequency consumption. This study defined significant, mild underweight and stunting, overweight and obesity based on percentiles of the NCHS/ CDC references. Using weight-for-age charts, approximately 91% (n=327) were categorized as significantly or mildly underweight. Using height-for-age charts, about 93% (n=334) were significantly or mildly stunted. This study found that 3.3% (n=12) and 1.7% (n=6) in this sample were overweight and obese, respectively, based on 85th and 95th percentiles of BMI-for-age curves. Pearson's correlation test found significant correlation between frequency of consumption for fruits group which is food group 2 (r=0.106, p<0.05) and vegetables group which is food group 3 (r=0.116, p<0.05), respectively with family wages and food group 5 (milk and dairy products) with family wages (r=0.156, p<0.01). For growth status, only BMI-for-age was correlated with family wages (r= - 0.54, p<0.05). In conclusion, the results demonstrate high prevalence of stunting and underweight, and low prevalence of overweight and obesity among these primary school children.
An Exploratory Study of Using Electronic-Tablet Based Menu in the Egyptian Hotel Industry: Management Perspective

Hotel industry has been experiencing the innovation of technology to support its services for decades. Menu has been considered as an effective tool for sales in food and beverage operations as it drives the production and selling decisions. The current study was conducted to investigate the potential effect of applying electronic-tablet-based menu (potential ordering experience) on information presenting and economies of scale and scope. Data was collected from the Egyptian hotels industry in Cairo. Thirty six food and beverage and restaurant managers [N=36] were invited to answer the questionnaire. Analyses were undertaken using SPSS version-20. The findings confirmed and described the relationships among dependent and independent variables. It was indicated that managers have a high perception of the potential ordering experience, which has the highest significant relationship with the informational role [r=0.60, P<. 000]. Furthermore, there was a moderate significant relationship with the scope economies role [r=0.45, P<. 006]. Finally, applying electronic-tablet-based menu only affects information presenting and economies of scope [Coefficient 1.05 and 0.72], respectively.
Exploring learning experiences and outcomes among cardiologists participating in a web conference workshop series

Introduction and purpose: The use of computers in continuing professional development (CPD) is growing, leading to questions about best practices in eLearning design for physicians. Studies using quantitative and qualitative methods have examined these questions, and design frameworks have been proposed to enhance program effectiveness. Qualitative studies offer rich descriptions of the interactions between physicians and learning technology and may offer insights into physician design preferences beyond what quantitative methods offer. This review synthesizes studies which used qualitative methods to explore physician preferences for eLearning implementation, and assesses preferences against the domains of an existing instructional design framework to suggest possible framework refinements. Methods: A systematic review was undertaken using an established methodology for identifying, appraising, and synthesizing evidence. Three researchers were involved in article selection and data analysis. Coding was guided by a validated eLearning design framework which suggested broad thematic domains and provided a lexicon for coding. Results: The search of electronic databases generated 1,537 unique citations. After screening, 25 studies were included in the review. Included studies represented 808 physicians who participated in postgraduate degree and medical specialist eLearning programs. Dominant themes related to eLearning design structures, content and media. The instructional design framework reflected the dominant themes with the exception of the recurring theme of Time. Discussion: Physicians show preferences for interactivity, skilled program facilitation, and program customization informed through learner analysis. They seek unbiased, evidence-based content, high usability, and ease of navigation. The design framework captured most key preferences; however, refinement could be made to the framework to prompt consideration of time requirements for learners and for program developers.
BCTT_A_166725 165..178

Márcia R Cominetti Wanessa F Altei Heloisa Sobreiro Selistre-deAraujo 1Department of Gerontology, Federal University of São Carlos, São Carlos, SP, Brazil; 2Department of Physiological Sciences, Federal University of São Carlos, São Carlos, SP, Brazil Abstract: The spread of cells from primary tumors toward distant tissues and organs, also known as metastasis, is responsible for most cancer-associated deaths. The metastasis cascade comprises a series of events, characterized by the displacement of tumor cells (TCs) from the primary tumor to distant organs by traveling through the bloodstream, and their subsequent colonization. The first step in metastasis involves loss of cell-cell and cellmatrix adhesions, increased invasiveness and migratory abilities, leading to intravasation of TCs into the blood or lymphatic vessels. Stationary TCs must undergo the process of epithelial-mesenchymal transition in order to achieve this migratory and invasive phenotype. Circulating tumor cells that have survived in the circulation and left the blood or lymphatic vessels will reach distant sites where they may stay dormant for many years or grow to form secondary tumors. To do this, cells need to go through the mesenchymal-epithelial transition to revert the phenotype in order to regain epithelial cell-to-cell junctions, grow and become a clinically relevant and detectable tumor mass. This work will review the main steps of the metastatic cascade and describe some strategies to inhibit metastasis by reducing cancer cell extravasation presenting recent studies in the context of breast cancer.
anti-BATF3 polyclonal antibody with trout BATF3a and BATF3b expressed in bacteria. I hope you will find the revised manuscript suitable for publication in Molecular Immunology. Thank you for your consideration. I look forward to your decision. Yours sincerely,

Basic leucine zipper transcription factor ATF-like (BATF) -3 is a member of the activator protein 1 (AP‐1) family of transcription factors and is known to play a vital role in regulating differentiation of antigen-presenting cells in mammals. In this study, two BATF3 homologues (termed BATF3a and BATF3b) have been identified in rainbow trout (Oncorhynchus mykiss). Both genes were constitutively expressed in tissues, with particularly high levels of BATF3a in spleen, liver, pyloric caecae and head kidney. BATF3a was also more highly induced by PAMPs and cytokines in cultured cells, with type II IFN a particularly potent inducer. In rIL-4/13 pre-stimulated cells, the viral PAMPS polyI:C and R848 had the most pronounced effect on BATF3 expression. BATF3 expression could also be modulated in vivo, following infection with Yersinia ruckeri, a bacterial pathogen causing redmouth disease in salmonids, or with the rhabdovirus IHNV. The results suggest that BATF3 may be functionally conserved in regulating the differentiation and activation of immune cells in lower vertebrates and could be explored as a potential marker for comparative investigation of leucocyte lineage commitment across the vertebrate phyla.
İLETİŞİM FAKÜLTESİ DERGİSİ / Comprehension Differences Between Art and Commercial Movie Watchers: an Empirical Study on Differences in the Interpretation of the Movie Hidden By Michael Haneke COMPREHENSION DIFFERENCES BETWEEN ART AND COMMERCIAL MOVIE WATCHERS: AN EMPIRICAL STUDY ON DIFFERENC

In the field of film studies, numerous empirical studies and theoretical models in formalist, semiotic and cognitivist paradigms addressed the question of how we understand movies. In this article, the ‘cognitivist’ paradigm will be taken as basis of theoretical background. Cognitivism looks at general human perceptual and cognitive capacities to deduce understanding of the movies and claims that films prompt audiences to apply situation models to what they see. Situation models are mental representations of the state of affairs described in a written or audio-visual text. Audiences ask themselves what, where, when and why the onscreen events are happening while watching a film. They know the common template structure which consists of an introduction of settings and characters, complicating actions, outcome and ending. This study is designed to address what happens when a film is an art film, of which the narrative line is fragmented so that there is no seamless cause-and-effect storyline. To answer such a question, the contemporary art film Hidden (2005) by M. Haneke was shown to two groups of participants (n:32), one of which was experienced in viewing art movies whilst the other group did not have any such experience. The results show that general world knowledge plays a bigger role than prior viewing experiences.
Session Number: Parallel Session 2C: Growth and Productivity Time: MONDAY, AUGUST 25, MORNING Paper Prepared for the30th General Conference of The International Association for Research in Income and Wealth

(To be revised after the completion of the paper) For a large and dynamic economy like China, it is important to understand the role of individual regions in the national economy. Along with the reform-induced marketisation and integration with the international economy, there have been ongoing changes in factor costs and hence comparative advantages across regions, and interregional resource reallocations. A proper assessment of regional economies and their potentials relies essentially on an accurate measure of regional productivity. However, data problems, especially the lack of properly measured capital input (stock and services), has been a major obstacle to such an assessment. In this study, we begin with a critical discussion of the problems in the official investment data. Then following the Jorgenson approach, for each major industry across regions, we firstly construct an alternative investment series, secondly, calculate its net capital stocks, and lastly estimate its capital services. The newly constructed capital input data is used in production function analysis to assess the effect of the reform on regional productivity disparities. Results of this study show that, first, shares of industrial sectors in most regions became more diversified after 1993. Second, economic growth of China‟s industry was mainly investment-driven. Third, in 1985, there were large gaps of labour productivity between rich regions and poor regions. Remarkable catch-up effect happened in those less-developed regions. Fourth, most regions experienced positive TFP growth during 1985-2005 and achieved significant productivity improvement since 1993.
Efficacy of Bimodal High-Voltage Monopulsed Current in the Treatment of Pressure Ulcer: A Systematic Review

Background: We aimed to systematically evaluate the efficacy of high-voltage pulsed current (HVPC) in the treatment of pressure ulcer. Methods: We searched the databases of PubMed, Cochrane Library, Elsevier and EMBASE to identify randomized controlled studies on the application of HVPC in pressure ulcer treatment, up to January 2019. Two authors independently screened the literature according to the inclusion and exclusion criteria, extracted the data and evaluated the quality. RevMan 5.3 software was used for statistical analysis. Four randomized controlled trials involving a total of 176 patients were included in the study. Results: Meta-analysis showed that the percentage of wound area reduction in the HVPC treatment group was higher than that in the control group (95%CI 24.59, 47.76, P<0.001). Descriptive analysis showed that there was no significant difference in wound healing between the HVPC treatment group and the control group. One study reported that there was contact dermatitis, and the rest of the studies reported no adverse events. Conclusion: Compared with the conventional therapy, the combination with HVPC therapy can reduce the area of pressure ulcers more effectively. However, due to the small number of the studies included in this evaluation, the conclusions need to be verified by more high-quality studies.
On the propagation of rainfall bias and spatial variability through urban pluvial flood modelling

The reliability of urban flood modelling can be largely improved if high-accuracy and fine-resolution rainfall estimates are available; however, this requires a very dense network of rainfall sensors and is usually not available due to limited budget and space. Adjustment and downscaling techniques are largely used respectively to post process the radar and rain gauge data to obtain better rainfall estimates in terms of accuracy and resolution. However, the combined application of these two types of techniques was seldom discussed in literatures, and its impact on the subsequent hydraulic modelling is unknown. This work implements a combined procedure of stochastic downscaling and gauge-based adjustment, aiming to evaluate its applicability to urban pluvial flood modelling. Unlike the adjustment process that reduces the rainfall input uncertainty (due to mean bias) through merging rainfall information from different sensors, the stochastic process of generating street-scale rainfall estimates actually causes additional uncertainty (due to spatial variability). This additional uncertainty will further propagate through hydraulic modelling and consequently affect the reliability of the resulting hydraulic outputs. The result of case study suggests that the uncertainty caused by the downscaling process could be larger than that reduced by the adjustment as the drainage area is very small.
Convergence Analysis of Quantum-Inspired Evolutionary Algorithms Based on The Banach Fixed-Point Theorem

In this paper, a convergence analysis of Quantum-Inspired Evolutionary Algorithms (QIEA) based on the Banach fixed-point theorem has been performed. An existing method, introduced originally by Zbigniew Michalewicz to classical genetic algorithms, has been adapted to the class of QIEA algorithms. A new fitness measure for quantum genotypes has been proposed, and the QIEA algorithm have been considered in the relevant metric space of quantum populations. The sufficient condition for the convergence of the algorithm has been discussed. Finally, the analysis has been illustrated on Quantum-Inspired Genetic Algorithm (QIGA). Streszczenie. W niniejszym artykule zaprezentowana została analiza zbieżności kwantowo-inspirowanych algorytmów ewolucyjnych (QIEA), oparta na wykorzystaniu twierdzenia Banacha o punkcie stałym odwzorowania zwężającego. Analiza polega na adaptacji znanej metody, zaproponowanej przez Zbigniewa Michalewicza dla klasycznych algorytmów genetycznych, do obszaru kwantowo-inspirowanych algorytmów ewolucyjnych poprzez wprowadzenie nowej miary oceny dopasowania genotypów kwantowych. Działanie algorytmu zostało rozważone w przestrzeni metrycznej populacji kwantowych, definiowanej przez tę miarę. Określony został warunek wystarczający dla zbieżności algorytmu QIEA. Analiza została zilustrowana przykładem wybranego kwantowo-inspirowanego algorytmu genetycznego (QIGA).
Spermine triggers a rapid plasma membrane-PIP2 response that is generated via PIP5K7 and PIP5K9 and stimulates the efflux of K in roots of Arabidopsis seedlings

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DETERMINANTS OF INTERNET ADOPTION IN MALAYSIAN AUDIT FIRMS

This study examines various factors associated with the adoption of Internet in audit firms. A research model that contains seven independent variables under four broad categories is postulated. The dependent variable, Internet adoption, is measured as the relative frequency of seven Internet applications used by audit firms. The results are based on primary data collected from 89 audit firms located in the northern region of Malaysia. Multiple regression analysis indicates that perceived usefulness, perceived ease of use and age of audit partners are significantly associated with Internet adoption. Implications of the findings and future research areas are discussed. Keywords-Internet; adoption; Malaysia; audit firms; innovation