Miracle-dz/UniFAR-FTUs huggingface dataset:
Genetic relationships among chickpea (Cicer arietinum) elite lines based on RAPD and agronomic markers

Utilization of diverse germplasm is needed to enhance the genetic diversity of cultivars. Genetically diverse lines provide ample opportunity to create favourable gene combinations and the probability of producing a unique genotypes increases in proportion to the number of gene by which the parents differ. The objective of this study was to evaluate the genetic relationships of 36 chickpea germplasm accessions using morphological traits and RAPD markers. Out of 33 primers, nine primers generated 44 polymorphic markers. The average polymorphic information content (PIC) was 0.43, ranging from 0.68 to 0.12. The lowest and the highest PIC value were recorded for primer OPB10 and OPJ-20, respectively. The average genetic distance (GD), based on Fst values among the 36 accessions was 0.397, ranging from 0.59 to 0.12. Cluster analysis based on morphological traits separated the accessions into three groups and based on RAPD data accessions formed in four distinct groups. The RAPD analysis clearly indicated that even with nine polymorphic primers, reliable estimation of genetic diversity could be obtained. The markers generated by RAPD assays can provide practical information for the management of genetic diversity.
Analysis of Canadian and American legislation for controlling exotic species in the Great Lakes

1. The legislation of the Great Lakes jurisdictions dealing with control of exotic species introduced through ballast water, canals, and recreational boating was analysed to determine whether the USA and Canada have the capacity to manage nuisance exotic species effectively. Despite the deleterious ecological effects attributed to exotic aquatic species, there is a lack of complementary legislation between Canada and the USA to remedy this problem. Current legislation is fragmented at the bilateral, national, and the state/provincial level. 2. American legislative initiatives are far ahead of Canada's, especially for regulating ballast water in oceanic shipping. Canada lacks strong federal and provincial legislation to regulate ballast water in shipping and to prevent the secondary spread of exotic aquatic species through watersheds. 3. Legislation to regulate ballast water is developing quickly among the US federal government and the Great Lakes states. However, legislation affecting the spread of exotic nuisance species via canals and recreational boaters is needed to complement ballast water laws and to give agencies a broader mandate for management. 4. Amendment of the Boundary Waters Treaty Act, the Fisheries Act, and the Canada Water Act could give the Canadian federal government authority to regulate ballast water in vessels entering the St Lawrence and to begin the rehabilitation of aquatic habitats impaired by nuisance exotic species. 5. Preventing further species introduction and spread through the Great Lakes basin requires restricting certain shipping and boating practices. This can be achieved only by the enactment of complementary laws among all the American and Canadian jurisdictions. Copyright © 2002 John Wiley & Sons, Ltd.
Entrepreneurship: Tenacity, Future Self-Continuity, and Inter-Temporal Risky Choice

This study examines entrepreneurship. It focuses on the effect of tenacity and future self-continuity (FSC) on inter-temporal risky choice in the entrepreneurial context. A total of 129 Chinese undergraduates participated in this survey. The results formulate that tenacity positively correlates with the risky choices and inter-temporal risky choices, in which commitment, endurance, and challenge play a major role. Meanwhile, FSC predicts the risk-return of the subjects. Higher FSC corresponds to higher expected inter-temporal risk-return. Furthermore, the multivariable regression analysis shows that there is a reciprocal effect when tenacity and FSC work together on subjects’ inter-temporal risky decision-making. FSC slightly mitigates both the pursuit of risky-return and the tolerance of time delay for the subjects with high tenacity. This implies that their worthwhile goal is to seek smooth income rather than to pursue an extreme high risk-return. These findings extend the research on personality, choice, and entrepreneurship and provide a guiding significance to the start-up.
A Systematic Approach to Review of in vitro Methods in Brain Tumour Research (SAToRI-BTR): Development of a Preliminary Checklist for Evaluating Quality and Human Relevance

Background A wide range of human in vitro methods have been developed and there is considerable interest in the potential of these studies to address questions related to clinical (human) use of drugs, and the pathobiology of tumours. This requires agreement on how to assess the strength of evidence available (i.e., quality and quantity) and the human-relevance of such studies. The SAToRI-BTR (Systematic Approach To Review of in vitro methods in Brain Tumour Research) project seeks to identify relevant appraisal criteria to aid planning and/or evaluation of brain tumour studies using in vitro methods. Objectives To identify criteria for evaluation of quality and human relevance of in vitro brain tumour studies; to assess the general acceptability of such criteria to senior scientists working within the field. Methods Stage one involved identification of potential criteria for evaluation of in vitro studies through: (1) an international survey of brain tumour researchers; (2) interviews with scientists, clinicians, regulators, and journal editors; (3) analysis of relevant reports, documents, and published studies. Through content analysis of findings, an initial list of criteria for quality appraisal of in vitro studies of brain tumours was developed. Stage two involved review of the criteria by an expert panel (Delphi process). Results Results of stage one indicated that methods for and quality of review of in vitro studies are highly variable, and that improved reporting standards are needed. 129 preliminary criteria were identified; duplicate and highly context-specific items were removed, resulting in 48 criteria for review by the expert (Delphi) panel. 37 criteria reached agreement, resulting in a provisional checklist for appraisal of in vitro studies in brain tumour research. Conclusion Through a systematic process of collating assessment criteria and subjecting these to expert review, SAToRI-BTR has resulted in preliminary guidance for appraisal of in vitro brain tumour studies. Further development of this guidance, including investigating strategies for adaptation and dissemination across different sub-fields of brain tumour research, as well as the wider in vitro field, is planned.
Using a narrative in sales promotions: An online vignette study

This paper examines how using a narrative in premium-based sales promotions influences consumers’ evaluation of and willingness to participate in such promotions. The results of online survey-based experiment support the notion that using a narrative may be considered as a valid tool to improve consumer response to premium-based sales promotions. In particular, the study shows that communicating a sales promotion in the form of a story increases hedonic and utilitarian value which in turn positively influences premium attractiveness and willingness to participate.
An Investigation Into the Prognostic Significance of High Proteasome PSB7 Protein Expression in Colorectal Cancer

Using unbiased proteomics, we had previously discovered that the catalytic proteasome subunit β type 7 (PSB7) protein is frequently overexpressed in colorectal adenocarcinomas. In this paper, we validate this finding and derive a prognostic significance for PSB7 by examining an expanded, well-annotated clinical cohort of 318 colorectal cancer patients. We found PSB7 protein levels to be similarly increased in both advanced stage primary disease and metastatic lesions. We then examined the prognostic value of PSB7 protein expression. Elevated PSB7 protein as well as PSMB7 mRNA levels showed associations with lower overall survival, particularly in female patients. The prognostic value of elevated PSB7 protein levels was highest for female patients who were older (>60 years of age at diagnosis) or who had received adjuvant chemotherapy. While high PSB7 did not retain its prognostic significance on multivariate analysis, we discuss the potential significance of PSB7 as a biomarker, considering its differential prognostic strength in different colorectal cancer patient groups and given its role as a subunit of the immunoproteasome for antigen presentation.
Effect of Organic-N Fertilizer on Growth and Some Physiological Parameters in Pepper Plants (Capsicum Annum L.)

ABSTRACT The research was carried out on pepper of “Buketen 50” and “Gorogled 6” cultivars, intended for production of red pepper for grinding. Pepper plants were grown in a phytostatic chamber under controller conditions. The plants were cultivated as soil crops. For this purpose soil from the Agroecological centre at the Agricultural University of Plovdiv (holder of a certificate for ecological farm) was used. The experiment was carried out under the following scheme: 1. Control—soil (no organic fertilizer application); 2. Soil and organic-N fertilizer application. The indicated variants were formed during the pricking of the plants in phase 2–4 true leaf. For the purpose of the experiment organic-N fertilizer Emosan (authorized for use in organic farming) was attached. The fertilizer was applied at rate equivalent to 10.0 l da−1. The results indicated that, applying organic-N fertilizer gave the vigorous plants expressed as plant height, leaves size as well as dry weight in both cultivars. The increase of dry biomass was mainly for the account of the increased mass of the above the ground organs. There was a positive effect of the fertilizer upon the functional activity of the photosynthetic apparatus/increased content of photosynthetic pigments, improved leaf gas exchange.
The Dominance of Blended Emotions: A Qualitative Study of Elementary Teachers’ Emotions Related to Mathematics Teaching

Examining the nature of teachers’ emotions and how they are managed and regulated in the act of teaching is crucial to assess the quality of teacher’s instructions. Despite the essential role emotions play in teachers’ lives and instruction, research on teachers’ emotions has not paid much attention on teachers’ state emotions in the context of daily teaching. Significant portion of literature has described teachers’ emotions by foregrounding trait emotions through deductive methodological approaches. This paper explored elementary teachers’ state and trait emotions while preparing for teaching and during teaching, reasons that underlie these emotions, and the relationship between their emotions and the quality of their mathematics instruction. Participants were seven elementary teachers working in the United States who participated in Holistic Individualized Coaching (HIC) professional development that consisted of 5 cycles of coaching over an year. For each coaching cycle pre-coaching conversation and post-coaching conversation data were collected regarding state emotions teachers felt in anticipation of teaching and during teaching retrospectively. Also, teachers responded adapted Teaching Emotion Scale (TES) that was aimed to measure trait emotions. In order to compare teachers’ emotions with instructional quality, coaching session were video recorded and analyzed to determine the quality of instruction. Findings of this study showed that teachers reported 6 categories of emotions (positive, negative, neutral, mixed-positive, mixed-negative, and mixed-complex), and often in non-typical ways (e.g., “not nervous,” “anxious but in a positive way”), and mixed emotions were the most dominant category. Also, teachers had more positive emotions anticipating teaching, than actually teaching the lesson, and there was no noticeable change of emotions across the 5 coaching cycles. The reason teachers felt mixed emotions reflected complex and context-specific nature of teaching, which was not articulated in the literature. There were no clear relationships between emotional experiences and instructional quality. This study allowed participants to freely describe their authentic, complex, overlapping, and ambiguous emotions in the context of active teaching, which contributes opening up the possibilities of diversifying teacher emotion research and shows the significance and usefulness of understanding teachers’ state emotions.
Preclinical Validation of SilkBridgeTM for Peripheral Nerve Regeneration

Silk fibroin (Bombyx mori) was used to manufacture a nerve conduit (SilkBridgeTM) characterized by a novel 3D architecture. The wall of the conduit consists of two electrospun layers (inner and outer) and one textile layer (middle), perfectly integrated at the structural and functional level. The manufacturing technology conferred high compression strength on the device, thus meeting clinical requirements for physiological and pathological compressive stresses. As demonstrated in a previous work, the silk material has proven to be able to provide a valid substrate for cells to grow on, differentiate and start the fundamental cellular regenerative activities in vitro and, in vivo, at the short time point of 2 weeks, to allow the starting of regenerative processes in terms of good integration with the surrounding tissues and colonization of the wall layers and of the lumen with several cell types. In the present study, a 10 mm long gap in the median nerve was repaired with 12 mm SilkBridgeTM conduit and evaluated at middle (4 weeks) and at longer time points (12 and 24 weeks). The SilkBridgeTM conduit led to a very good functional and morphological recovery of the median nerve, similar to that observed with the reference autograft nerve reconstruction procedure. Taken together, all these results demonstrated that SilkBridgeTM has an optimized balance of biomechanical and biological properties, which allowed proceeding with a first-in-human clinical study aimed at evaluating safety and effectiveness of using the device for the reconstruction of digital nerve defects in humans.
Association of Alanine Aminotransferase With Different Metabolic Phenotypes of Obesity in Children and Adolescents: The CASPIAN-V Study

Aim: To determine the association of alanine aminotransferase with different metabolic phenotypes of obesity in a nationally- representative sample of Iranian children and adolescents. Methods: This national study was conducted in the framework of the fifth survey of a national surveillance program entitled Childhood and Adolescence Surveillance and Prevention of Adult Non-communicable Disease study. Participants consisted of 4,200 subjects aged 7–18 years, who were recruited by multistage random cluster sampling from 30 provinces in Iran. They were categorized to normal weight and obese groups and in each group those with and without MetS components. Results: Overall, 3,843 of participants completed the survey (response rate: 91.5%). Their mean (SD) age was 12.58 (3.15) years; 52.6% were boys, and 72.7% lived in urban areas. Mean of alanine aminotransferase (ALT) in subjects with abdominal obesity and general obesity was 8.81 (95% CI: 7.99–9.62) (IU/L) and 8.87 (95% CI: 7.28–10.46) (IU/L), respectively. According to the adjusted model, one unit increment in ALT increased odds of being metabolically non-healthy obese (MNHO) by 2% compared to metabolically healthy non-obese (MHNO) [adj.OR (95% CI): 1.02 (1.01–1.04)]. Also, subjects in the third and fourth quartiles of serum ALT had significantly greater odds of being MNHO than those in its first quartile [Q3/Q1: adj. OR (95% CI): 3.85 (1.70–8.71); Q4/Q1: Adj. OR (95% CI): 3.63 (1.51–8.73)]. Conclusion: This large population-based study revealed significant associations between metabolic phenotypes of obesity and ALT level.
Word’s Contextual Predictability and Its Character Frequency Effects in Chinese Reading: Evidence From Eye Movements

The present study sought to establish how a word’s contextual predictability impacts the early stages of word processing when reading Chinese. Two eye-movement experiments were conducted in which the predictability of the target two-character word was manipulated; the frequency of the target’s initial character was manipulated in Experiment 1, as was the target’s end character frequency in Experiment 2. No reliable interaction effect of predictability with initial character frequency was observed in Experiment 1. Reliable interactions of word predictability with end character frequency were observed in Experiment 2. The end character frequency effects, in which the words with high-frequency end characters were fixated for a shorter time and re-fixated less often, were only observed when reading unpredictable words. Reliable interactions were also observed with incoming saccade length, as high-frequency end character words elicited longer saccades to themselves than low-frequency end character words when reading predictable words. The effects of pervasive predictability on measures of fixation time, probability, and saccade length were noted in both experiments. Our findings suggest that a word’s contextual predictability facilitates the processing of its constituent characters.
Multi-level Semantic Representation Model for Code Search

With the huge amount of open-source software is publicly available today, code search has become more and more important to software development. Matching natural language(NL) between programming language(PL) cross the semantic gap is the key to the code search problem. In this paper, we introduce a word-based Multi-level Semantic Representation (MSR) model from the perspective of text representation to maximum semantic matching. Then we perform a series of experiments to find the significance of different parts in code snippets when modeling semantic relevance between natural language and programming language. The conclusion can be used to support further study on semantic matching modeling between PL and NL like the neural matching model.
Classification of Larval and Adult Delta Smelt to Nursery Areas by Use of Trace Elemental Fingerprinting

Abstract Different environmental conditions among habitats may generate unique elemental patterns within fish otoliths that can be used to trace the life history as well as the potential natal origin of migratory species. We investigated the use of trace elements in otoliths as natural tags for determining the natal origins of larval and adult delta smelt Hypomesus transpacificus within a single estuary. Larval fish were collected at potential natal sites within the San Francisco Bay Estuary—the North, Central, South, and West Delta areas, Suisun Bay, and Napa River—during May–June 1999; adults were collected in November 1999 throughout Suisun Bay. Using laser ablation inductively coupled plasma mass spectrometry, we assayed trace elements from core (natal) regions of the otolith (Sr:Ca, Mg:Ca, and Ba:Ca ratios). Linear discriminant function analysis (LDFA) was 90.9–100% successful at classifying larval fish to their natal habitats (Napa River, Sacramento River, and Delta). Adults of unknown natal origin .
The Role of Adjuvant Treatment in Craniofacial Malignancy: A Critical Review

Background: Tumors originating from the craniofacial region usually present in a locally advanced stage with frequent involvement of adjacent sites and have a strong tendency for local recurrence in the absence of adjuvant therapy, even when the original surgical resection was presumed to be radical. In the past decades, several advances in the radiological diagnosis and treatment of craniofacial malignancies have been introduced. There are, however, no randomized trials that define the optimal multimodal treatment of these tumors because of their rarity as well as heterogeneity in both histology and site of origin. The aim of this study was to conduct a critical review of the role of adjuvant therapy in the treatment of craniofacial malignancy. Method: We conducted a critical review of the past and contemporary literature available, focusing on adjuvant oncological treatments of the most common craniofacial malignancies. Results: Preoperative radiotherapy can have a documented role in the treatment of olfactory neuroblastoma and soft tissue sarcoma, while preoperative chemotherapy can be advocated in the treatment of sinonasal undifferentiated carcinoma, neuroendocrine carcinoma, olfactory neuroblastoma, and craniofacial sarcoma (both soft-tissue and high-grade osteosarcoma). Postoperative radiotherapy has a well-established role in the treatment of most craniofacial malignancies. The role of postoperative chemotherapy is unclear in most histologies, but is commonly used during the treatment of well-selected cases of paranasal sinus carcinoma, olfactory neuroblastoma, mucosal melanoma, soft tissue sarcoma and high-grade craniofacial osteosarcoma. Discussion: Alongside developments in surgery, there have also been improvements in diagnostics, radiotherapy, and chemotherapy. Implementation of novel radiation techniques allows delivery of higher radiation doses while minimizing irradiation-related morbidity. Better understanding of tumor biology allows the construction of more complex treatment strategies, incorporating adjuvant chemotherapy either pre- or postoperatively. In the era of personalized targeted therapy, rapid strides are being made to identify specific tumor-targets for use of novel biologic agents, with the potential to change current management paradigms.
Draft Genome Sequence of a Multicountry Outbreak-Related Listeria monocytogenes Sequence Type 1247 Strain, VLTRLM2013

We sequenced the genome of a multicountry outbreak-related Listeria monocytogenes sequence type 1247 strain (VLTRLM2013) that was isolated from a vacuum-packaged sliced salted salmon product of an Estonian fish-processing company that was obtained from an Estonian retail outlet in 2013. ABSTRACT We sequenced the genome of a multicountry outbreak-related Listeria monocytogenes sequence type 1247 strain (VLTRLM2013) that was isolated from a vacuum-packaged sliced salted salmon product of an Estonian fish-processing company that was obtained from an Estonian retail outlet in 2013.
Draft Genome Sequence of Streptomyces sp. Strain ventii, Isolated from a Microbial Mat near Hydrothermal Vents within the Axial Seamount in the Pacific Ocean, and Resequencing of the Type Strains Streptomyces lonarensis NCL 716 and Streptomyces bohaiensis 11A07

The draft genome of Streptomyces sp. strain ventii, an environmental isolate recovered from deep-sea hydrothermal vents in the Pacific Ocean, is presented along with the resequenced draft genomes of the type strains Streptomyces bohaiensis 11A07 and Streptomyces lonarensis NCL 716. ABSTRACT The draft genome of Streptomyces sp. strain ventii, an environmental isolate recovered from deep-sea hydrothermal vents in the Pacific Ocean, is presented along with the resequenced draft genomes of the type strains Streptomyces bohaiensis 11A07 and Streptomyces lonarensis NCL 716.