Miracle-dz/UniFAR-FTUs huggingface dataset:
The Effects of Simulation-Based Advanced Life Support Education for Nursing Students

Advanced life support education for nursing students is very important because nurses are first responders in emergency situations. The purpose of this study was to identify the effects of simulation-based advanced life support education on nursing students' knowledge, performance, self-efficacy, and teamwork. A nonequivalent control group posttest-only design was used. Fourth-year nursing students were randomly assigned to either simulation-based Korean Advanced Life Support (n = 30) or lecture-based education (n = 30) groups. Data were analyzed using descriptive statistics and the Mann-Whitney U test. The experimental group showed statistically significant higher scores in knowledge (P < .001), performance (P < .001), and self-efficacy (P = .049) when compared with the control group. However, there was no significant difference in teamwork scores between the two groups (P = .529). The 4.5-hour simulation-based Korean Advanced Life Support education was more effective than the 4.5-hour lecture-based education for nursing students in terms of knowledge, performance, and self-efficacy. Nurse educators should adopt simulation-based advanced life support education into the curriculum for the optimal competence of nursing students.
2019 ESC Guidelines on diabetes, pre-diabetes, and cardiovascular diseases developed in collaboration with the EASD.

Authors/Task Force Members: Francesco Cosentino* (ESC Chairperson) (Sweden), Peter J. Grant* (EASD Chairperson) (United Kingdom), Victor Aboyans (France), Clifford J. Bailey (United Kingdom), Antonio Ceriello (Italy), Victoria Delgado (Netherlands), Massimo Federici (Italy), Gerasimos Filippatos (Greece), Diederick E. Grobbee (Netherlands), Tina Birgitte Hansen (Denmark), Heikki V. Huikuri (Finland), Isabelle Johansson (Sweden), Peter Jüni (Canada), Maddalena Lettino (Italy), Nikolaus Marx (Germany), Linda G. Mellbin (Sweden), Carl J. € Ostgren (Sweden), Bianca Rocca (Italy), Marco Roffi (Switzerland), Naveed Sattar (United Kingdom), Petar M. Seferovi c (Serbia), Miguel Sousa-Uva (Portugal), Paul Valensi (France), David C. Wheeler (United Kingdom)
Yb-Fibre laser welding of 6 mm duplex stainless steel 2205

Duplex stainless steel (DSS) is one of the materials of choice for structural and nuclear applications, having high strength and good corrosion resistance when compared with other grades of stainless steel. The welding process used to join these materials is critical as transformation of the microstructure during welding directly affects the material properties. High power laser welding has recently seen an increase in research interest as it offers both speed and flexibility. This paper presents an investigation into the important parameters affecting laser welding of DSS grade 2205, with particular focus given to the critical issue of phase transformation during welding. Bead-on-plate melt-run trials without filler material were performed on 6 mm thick plates using a 5 kW Yb-fibre laser. The laser beam was characterized and a Design of Experiment approach was used to quantify the impact of the process parameters. Optical metallographic methods were used to examine the resulting microstructures. Copyright line will appear here. Peer-review under responsibility of the Bayerisches Laserzentrum GmbH.
Title Diacylglycerol kinase zeta inhibits myocardial atrophy and restores cardiac dysfunction in streptozotocin-induced diabetes mellitus

Background: Activation of the diacylglycerol (DAG)-protein kinase C (PKC) pathway has been implicated in the pathogenesis of a number of diabetic complications. Diacylglycerol kinase (DGK) converts DAG to phosphatidic acid and acts as an endogenous regulator of PKC activity. Akt/PKB is associated with a downstream insulin signaling, and PKCβ attenuates insulin-stimulated Akt phosphorylation. Methods and Results: We examined transgenic mice with cardiac-specific overexpression of DGKζ (DGKζ-TG) compared to wild type (WT) mice in streptozotocin-induced (STZ, 150 mg/kg) diabetic and nondiabetic conditions. After 8 weeks, decreases in heart weight and heart weight/ body weight ratio in diabetic WT mice were inhibited in DGKζ-TG mice. Echocardiography at 8 weeks after STZ-injection demonstrated that decreases in left ventricular end-diastolic diameter and fractional shortening observed in WT mice were attenuated in DGKζ-TG mice. Thinning of the interventricular septum and the posterior wall in diabetic WT hearts were blocked in DGKζTG mice. Reduction of transverse diameter of cardiomyocytes isolated from the left ventricle in diabetic WT mice was attenuated in DGKζ-TG mice. Cardiac fibrosis was much less in diabetic DGKζ-TG than in diabetic WT mice. Western blots showed translocation of PKCβ and δ isoforms to membrane fraction and decreased Akt/PKB phosphorylation in diabetic WT mouse hearts. However in diabetic DGKζ-TG mice, neither translocation of PKC nor changes Akt/PKB phosphorylation was observed. Conclusion: DGKζ modulates intracellular signaling and improves the course of diabetic cardiomyopathy. These data may suggest that DGKζ is a new therapeutic target to prevent or reverse diabetic cardiomyopathy. Introduction Diabetes mellitus is a serious medical problem. It is complicated by progressive cardiovascular diseases, including arteriosclerosis, myocardial infarction, and congestive heart Published: 4 February 2008 Cardiovascular Diabetology 2008, 7:2 doi:10.1186/1475-2840-7-2 Received: 16 December 2007 Accepted: 4 February 2008 This article is available from: http://www.cardiab. com/content/7/1/2 © 2008 Bilim et al; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Cardiovascular Diabetology 2008, 7:2 http://www.cardiab. com/content/7/1/2
Genetic drift during the spread phase of a biological invasion

Recent theoretical and experimental models have revealed the role played by evolution during species spread, and in particular have questioned the influence of genetic drift at range edges. By investigating the spread of an aquatic invader in patchy habitats, we quantified genetic drift and explored its consequences for genetic diversity and fitness. We examined the interplay of gene flow and genetic drift in 36 populations of the red swamp crayfish, Procambarus clarkii, in a relatively recently invaded wetland area (30 years, Brière, northwest France). Despite the small spatial scale of our study (15 km2), populations were highly structured according to the strong barrier of land surfaces and revealed a clear pattern of colonization through watercourses. Isolated populations exhibited small effective sizes and low dispersal rates that depended on water connectivity, suggesting that genetic drift dominated in the evolution of allele frequencies in these populations. We also observed a significant decrease in the genetic diversity of isolated populations over only a 2‐year period, but failed to demonstrate an associated fitness cost using fluctuating asymmetry. This study documents the possible strong influence of genetic drift during the spread of a species, and such findings provide critical insights into the current context of profound rearrangements in species distributions due to global change.
Examining sex as a predictor and moderator of treatment outcomes for binge-eating disorder: Analysis of aggregated randomized controlled trials.

OBJECTIVE This study examined whether sex predicted and/or moderated treatment outcomes among men and women who participated in binge-eating disorder (BED) randomized controlled trials (RCTs). METHOD Data were aggregated from RCTs performed at one medical center. RCTs tested cognitive-behavioral therapy, behavioral weight loss, multimodal treatment, and/or control conditions. Participants were 660 adults, both men (n = 170) and women (n = 490), with Diagnostic and Statistical Manual-fourth edition (DSM-IV)-defined BED. Doctoral-level research-clinicians assessed participants using structured interviews and established self-report measures of eating-disorder psychopathology and depression, and measured height and weight. Assessments occurred at baseline, throughout treatment, and at post-treatment. RESULTS Sex was not a significant moderator of any treatment outcomes. Mixed models revealed sex had a main effect: men had lower eating-disorder psychopathology and lost more weight than women over the course of treatment. DISCUSSION Both epidemiological and RCT studies report disparities in treatment-seeking between men and women with BED. Despite this, men have comparable or better treatment outcomes compared with women, including significantly greater weight loss. Thus, disseminating evidence-based BED treatments is promising for both men and women. Additional research is necessary, however, to understand treatment effects-including other predictors and moderators of outcomes-across diverse providers, treatment settings, and patient groups.
A Highly Responsive Organic Image Sensor Based on a Two‐Terminal Organic Photodetector with Photomultiplication

Highly responsive organic image sensors are crucial for medical imaging applications. To enhance the pixelwise photoresponse in an organic image sensor, the integration of an organic photodetector with amplifiers, or the use of a highly responsive organic photodetector without an additional amplifying component, is required. The use of vertically stacked, two‐terminal organic photodetectors with photomultiplication is a promising approach for highly responsive organic image sensors owing to their simple two‐terminal structure and intrinsically large responsivity. However, there are no demonstrations of an imaging sensor array using organic photomultiplication photodetectors. The main obstacle to a sensor array is the weak‐light sensitivity, which is limited by a relatively large dark current. Herein, a highly responsive organic image sensor based on monolithic, vertically stacked two‐terminal pixels is presented. This is achieved using pixels of a vertically stacked diode‐type organic photodetector with photomultiplication. Furthermore, applying an optimized injection electrode and additionally stacked rectifying layers, this two‐terminal device simultaneously demonstrates a high responsivity (>40 A W−1), low dark current, and high rectification under illumination. An organic image sensor based on this device with an extremely simple architecture exhibits a high pixel photoresponse, demonstrating a weak‐light imaging capability even at 1 µW cm−2.
The Influence of Ingestion Glucose Beverage Before Graded Exercise to Exhaustion on Saliva IgA Concentration in Hypoxia and Normoxia Environment

In addition to exercise, hypoxia environment might induce higher immune stress. The present study was to investigate the ingestion of glucose before graded exercise to exhaustion in hypoxia environment on immune responses. Eight healthy college students (age:22.1 ±0.4 yrs; weight: 71.6 ±2.3kg; height:171.4 ±2.3cm ) participated in this study. Subjects were ingested either 75g/250ml glucose (G) or placebo (P) drink 30 min before exercise on a cycle ergometer in the hypoxia (H) or normoxia (N) chamber. Exercise intensity was initiated at 75W and was increased 25W every 3 min until volitional fatigue. Saliva samples were collected at fasting, before exercise, immediately after exercise, and 1 hour after exercise. The results showed that the saliva IgA concentrations were slightly increased after the ingestion of glucose but there were no significant difference between the trials. There were no difference in salivary flow rate and adjusted IgA concentrations. The current data suggested that the ingestion of glucose before a single bout graded exercise to exhaustion did not alter salivary immune response in hypoxia environment.
MINIMAX VARIATIONAL PRINCIPLE FOR STEADY BALANCED SOLUTIONS OF THE ROTATING SHALLOW WATER EQUATIONS

Two well-known variational principles for geophysical flows are combined into a single minimax principle that characterizes distinguished steady solutions of the rotating shallow water (RSW) equations. On the one hand, in the limit of small Rossby number ǫ, in which the dynamics becomes quasi-geostrophic and closes terms of the potential vorticity field Q, steady coherent states are characterized as minimizers of (generalized) enstrophy A at a given value of total energy H. On the other hand, for small amplitude motions at finite ǫ balanced states resulting from geostrophic adjustment are characterized as minimizers of the total energy H subject to a given potential vorticity Q. Moreover, the organization into a coherent state through potential vorticity mixing occurs on a slow time scale relative to the fast time scale of adjustment through inertia-gravity wave radiation. These two complementary principles suggest a variational characterization of steady balanced states for the RSW equations at finite ǫ. Namely, the functional A+θH, where θ <0 is a parameter, is first maximized over all RSW fields with given Q, and then minimized over all Q. Any such minimax critical point of A+θH is an exact steady solution of the RSW equations, which represents a physically relevant equilibrium state at finite Rossby number. This minimax principle is implemented numerically for zonal shear flows, and branches of solutions are computed to first-order in ǫ. The results quantify the breakdown of quasi-geostrophy and the asymmetry between cyclonic and anticyclonic structures. In addition, the O(ǫ)-correction is computed for a model of the zonally-averaged winds in Jupiter’s weather layer.
The association between the neighbourhood social environment and obesity in Brazil: a cross-sectional analysis of the ELSA-Brasil study

Objective To investigate the association between the neighbourhood social environment, including social cohesion, perceived neighbourhood safety, perceived neighbourhood violence, and obesity in Brazil. Design Cross-sectional study. Setting 6 state capitals in Brazil (Salvador, Vitoria, Belo Horizonte, Porto Alegre, Sao Paulo and Rio de Janeiro) Participants Current or former employees of five federal universities and one research centre in each of the six Brazilian state capitals who were participants of the baseline wave (2008–2010) of the Brazilian Longitudinal Study of Adult Health (n=11 456; 56% women; 56% White, 28% Brown, and 16% Black). Primary outcome measure Obesity, based on measured weight and height, and defined as having a body mass index ≥30 kg/m2. Results No associations were found between the neighbourhood social environment and obesity among men. In multilevel logistic regression models adjusted for age, education, skin colour, state of residence, and individual-level social cohesion and perceived violence scores, respectively, women living in the least socially cohesive neighbourhoods and in those perceived as most violent had higher odds of obesity compared with their counterparts (OR=1.25, 95% CI=1.02–1.53; OR=1.28, 95% CI=1.04–1.56, respectively). When stratified by neighbourhood socioeconomic status (SES)—defined based on number of people per household, proportion of children 0–4 years, median income and per cent of white residents at the neighbourhood level—results for social cohesion and for violence remained only for women residing in high SES and low SES neighbourhoods, respectively. Conclusions In this civil-servant sample in six large cities in Brazil, the neighbourhood social environment was associated with obesity among women, but not men. Neighbourhood-level interventions to increase social cohesion and reduce violence may help in the prevention of obesity among women in Brazil.
Research article ENHANCING THE VASE LIFE OF TULIP (TULIPA GESNERIANA L.) USING VARIOUS PULSING SOLUTIONS OF HUMIC ACID AND NPK

The aim of this experiment was to investigate the effect of various humic acid concentrations and NPK levels for vase life response of Tulip (Tulipa gesneriana L.) cv. Triumph. The data was statistically analysed by using complete randomized design (CRD) in three replications and observations were recorded at two intervals (I st at: 5 days, 2 nd at: 10 days). Three concentrations of humic acid (25, 50, and 75 ml/l) along with NPK dose was applied which were compared with control. The statistical results revealed that all measured traits increased with increase in humic acid concentration and treatment combination of humic acid (HA) and NPK produced a significant difference in post harvest attributes than a single application. The highest values for quality parameters like scape length (30.95 cm and 34.12 cm), tepal diameter (10.34 mm and 11.89 mm), water uptake (66.95cm 3 and 62.87cm 3 ), fresh weight (33.21g and 38.32g) and minimum stem curvature percentage (17.23% and 19%) were observed in T5 (75 ml/l humic acid + 10 g/l NPK) as compared to control (T0=distilled water) at two intervals. Concerning the influence of humic acid and NPK for vase life, T5 also had a superior effect on days for vase life (18.70 days) as compared to other treatments.
An exploratory investigation of the effect of naturalistic light on fatigue and subjective sleep quality in stroke patients admitted for rehabilitation: A randomized controlled trial.

BACKGROUND Daylight entrains the central circadian pacemaker to the 24-hour day and is crucial for optimal alertness and sleep-quality. Rehabilitation patients tend to lack exposure to sufficient natural light. OBJECTIVE Installed diurnal naturalistic light may reduce the known disrupted sleep quality and fatigue seen in post stroke patients. METHODS Stroke patients were randomized to either an intervention rehabilitation unit (IU) equipped with naturalistic lighting (artificial sunlight spectrum) or to a control rehabilitation unit (CU) with standard indoor lighting. At inclusion and discharge, fatigue and subjective sleep quality were measured. RESULTS Ninety stroke patients were included between May 2014, and June 2015. At discharge, patients from the IU experienced less fatigue than the CU patients, based on the Multidimensional Fatigue Inventory questionnaire general (IU, n = 28; CU, n = 30; diff - 20.6%, 95% confidence interval (CI) [- 35.0%; - 3.0%]; P = 0.025) and the Rested Statement (IU, n = 28; CU, n = 30; diff + 41.6%, 95% CI [+4.6%; +91.8%]; P = 0.025). No differences were detected between groups in sleepiness or subjective sleep quality by the Pittsburgh Sleep Quality Index. CONCLUSIONS Fatigue was significantly reduced in rehabilitation patients exposed to naturalistic lighting during admission.
POLITECNICO DI TORINO Repository ISTITUZIONALE Sensitivity Analysis of the Transmission Chain of a Horizontal Machining Tool Axis to Design and Control Parameters /

Sensitivity Analysis of the Transmission Chain of a Horizontal Machining Tool Axis to Design and Control Parameters / Stefano Mauro; Stefano Pastorelli; Tharek Mohtar. In: ADVANCES IN MECHANICAL ENGINEERING. ISSN 16878132. ELETTRONICO. January-December 2014 vol. 6(2014). Original Sensitivity Analysis of the Transmission Chain of a Horizontal Machining Tool Axis to Design and Control Parameters
Host plant‐related genomic differentiation in the European cherry fruit fly, Rhagoletis cerasi

Elucidating the mechanisms and conditions facilitating the formation of biodiversity are central topics in evolutionary biology. A growing number of studies imply that divergent ecological selection may often play a critical role in speciation by counteracting the homogenising effects of gene flow. Several examples involve phytophagous insects, where divergent selection pressures associated with host plant shifts may generate reproductive isolation, promoting speciation. Here, we use ddRADseq to assess the population structure and to test for host‐related genomic differentiation in the European cherry fruit fly, Rhagoletis cerasi (L., 1758) (Diptera: Tephritidae). This tephritid is distributed throughout Europe and western Asia, and has adapted to two different genera of host plants, Prunus spp. (cherries) and Lonicera spp. (honeysuckle). Our data imply that geographic distance and geomorphic barriers serve as the primary factors shaping genetic population structure across the species range. Locally, however, flies genetically cluster according to host plant, with consistent allele frequency differences displayed by a subset of loci between Prunus and Lonicera flies across four sites surveyed in Germany and Norway. These 17 loci display significantly higher FST values between host plants than others. They also showed high levels of linkage disequilibrium within and between Prunus and Lonicera flies, supporting host‐related selection and reduced gene flow. Our findings support the existence of sympatric host races in R. cerasi embedded within broader patterns of geographic variation in the fly, similar to the related apple maggot, Rhagoletis pomonella, in North America.
The Quickest Delivery on the Super Pipeline Based Logistic System

In this paper, we consider the problem of delivering replenishments from source to sink nodes on a delivery line in minimum time interval, where the halfway stopping and intercrossing are forbidden. We call this problem the quickest delivery problem, and define it in a mathematical way. We point out that this problem is equivalent to the problem of moving time-position segments along the time axis such that any two segments are not intersected with each other and the total time is minimized. Based on this point, we formulate the quickest delivery problem as a minimization problem, with the non- intercrossing constraints as non-intersection constraints among time-position segments in four cases. We can solve this minimization problem by using optimization toolboxes. Experiments confirm the effectiveness of our model.
Flood Frequency Analysis of Annual Maximum Stream Flows using L-Moments and TL-Moments Approach

Flood frequency analysis (FFA) is the estimation of how often a specified event will occur. Before the estimation can be done, analyzing the stream flows data are important in order to obtain the probability distribution of flood. By knowing the probability distribution, prediction of flood events and their characteristics can be determined. The aim of this study is to perform the FFA of annual maximum stream flows over station in Negeri Sembilan, Malaysia by using the L-Moments (LMOM) and TL-Moments with trimming only one smallest value (TLMOM1) approach. The most suitable distribution was determined by the use of MADI and moments ratio diagram. The result shows that GLO distribution to be the best distribution fitted the data of annual maximum stream flows for stations in Negeri Sembilan, Malaysia.
Title Multi-manifold metric learning for face recognition basedon image sets

In this paper, we propose a new multi-manifold metric learning (MMML) method for the task of face recognition based on image sets. Different from most existing metric learning algorithms that learn the distance metric for measuring single images, our method aims to learn distance metrics to measure the similarity between manifold pairs. In our method, each image set is modeled as a manifold and then multiple distance metrics among different manifolds are learned. With these distance metrics, the intra-class manifold variations are minimized and inter-class manifold variations are maximized simultaneously. For each person, we learn a distance metric by using such a criterion that all the learned distance metrics are person-specific and thus more discriminative. Our method is extensively evaluated on three widely studied face databases, i.e., Honda/UCSD database, CMU MoBo database and Youtube Celebrities database, and compared to the state-of-the-arts. Experimental results are presented to show the effectiveness of the proposed method.