Miracle-dz/UniFAR-FTUs huggingface dataset:
Investigation Into Road Simulation Experiment of Powertrain and Its Key Components of a Fuel Cell Passenger Car

An elementary but integrated experiment is described,including the real road load sample on proving ground,road load reproduction on vibration test rig,total vehicle road simulation test and key components vibration tests.Remote parameter control technology is adopted to reproduce the real road load on 4 poster road simulator and six-degree-of-freedom vibration table which are used respectively for total vehicle and components vibration tests.After the total vehicle vibration test,vehicle driving performance and fuel economy are regularly measured on chassis dynamometer to validate powertrain system degradation resulting from vibration.The fuel economy was found to have decreased by 17.59% and structural damage of vehicle body structure and components were observed in the evaluation of structure strength and operation malfunction of powertrain system.The systematic experiment process and validation method helped to improve the durability,reliability and life of fuel cell vehicle,powertrain and its key components.
The Relationship between Dominant Coping Strategies and Socio-Psychological Characteristics of Personality

Coping behavior is considered as the main variable that affects the ability to resist the negative effects of various stressors. Factors and mechanisms for choosing certain coping strategies are of particular interest. Our study aims to identify the relationship between dominant coping behavior strategies and sociopsychological characteristics of personality. In a pilot study organized by the cross-section method, a survey of 57 Ukrainian teachers selected by random sampling was conducted. In accordance with the purpose of the study, diagnostic tools were used, such as versions of the Russian-language adaptation of the test of ways to overcome R. Lazarus and S. Folkman and the test-questionnaire R. Cattell. The main hypotheses of this study were tested by correlation analysis. The close connection between the dominant strategies of coping behavior and socio-psychological characteristics of the individual is revealed. The results obtained indicate the personal determinants of coping behavior. The study of the relationship between human personality traits and coping strategies will predict the coping reactions of the subject based on the diagnosis of his personality traits, as well as a deeper understanding of the mechanisms of integrative work of the personality as a subject.
Potential Use of Tailored Citicoline Chitosan-Coated Liposomes for Effective Wound Healing in Diabetic Rat Model

Purpose This study aimed to formulate citicoline-loaded chitosan-coated liposomes (CT-CS-LPs) for topical administration and evaluated for wound healing in a diabetic animal model. Methods CT-LPs were formulated via a thin-film hydration approach and coated with chitosan (CS). Box-Behnken statistical design investigated the effects of lipid amount, chitosan concentration, and cholesterol amount on vesicle diameter, surface charge, and entrapment efficiency. The potential of the optimized CT-CS-LPs gel for wound healing was further evaluated in streptozocin-induced diabetic rats. The different healing stages were evaluated by several techniques, including general and special staining techniques, in addition to antibody immunohistochemistry. Results The optimized CT-CS-LPs obtained had a mean size of 211.6 nm, a 50.7% entrapment efficiency, and a positive surface charge of 32.1 mV. In addition, the optimized CT-CS-LPs exhibited in vitro sustained release behavior. The in vivo experiments revealed that treatment with the optimized CT-CS-LPs boosts the healing process of the skin wound in diabetic rats by reducing inflammation, accelerating re-epithelization, angiogenesis, fibroblast proliferation, and connective tissue remodeling, leading to rapid wound closure. Conclusion Chitosan-coated liposomes containing citicoline have emerged as a potential approach for promoting the healing process in diabetic rats. However, the therapeutic effectiveness of the suggested approach in diabetic patients needs to be investigated.
Subject-Dependent Emotion Recognition System Based on Multidimensional Electroencephalographic Signals: A Riemannian Geometry Approach

Emotion recognition plays an important role in human computer interaction systems as it helps the computer in understanding human behavior and their decision making process. Using Electroencephalographic (EEG) signals in emotion recognition offers a direct assessment on the inner state of human mind. This study aims to build a subject dependent emotion recognition system that differentiate between high and low levels of valance and arousal, using multidimensional EEG signals. Our system offers a transfer learning- minimum distance to Riemannian mean (TL-MDRM) framework. In this work, we perform two pre-processing stages. In the first stage, we analyze the EEG signals to investigate their non-Gaussianity and determine the most appropriate signal distribution. Using several statistical and goodness of fit tests, T-distribution was found to be the most appropriate distribution. Covariance matrix estimations plays a crucial step in manifold learning technique, based on the most suitable signal distribution the covariance matrix estimation technique is chosen. In the second stage, we perform transfer learning to deal with cross-session variability by generating a unique reference point for each participant and performing affine transformation for the covariance matrices on the symmetric positive definite (SPD) manifold around this point. The results show that, TL process improved the performance even when assuming Gaussian distribution, while assuming T-distribution with TL improved the performance further.
Application of Accentuated Eccentric Loading to Elicit Acute and Chronic Velocity and Power Improvements: A Narrative Review

Accentuated eccentric loading (AEL) employs heavier load magnitudes in eccentric actions than concentric actions of complete stretch-shortening cycles. In doing so, unique neuromuscular and molecular responses are expected to result in acute post-activation performance enhancements, as evidenced by increased movement velocity or power. Improvements are dependent upon load selection, which varies across exercises, such as jumps and bench press throws (eccentric: 20-40 kg or 20-30% of body mass; concentric: body mass only), and squats and bench press (eccentric: 77.3-120% One-Repetition Maximum (1-RM); concentric: 30-90% 1-RM). The efficacy of AEL is dependent upon the concentric load used, which in turn is influenced by the magnitude of the eccentric load. Greater strength relative to body mass may enable the maintenance of technique and pacing during AEL, necessary for resultant performance enhancements, particularly when using eccentric loads exceeding the individual’s concentric 1-RM. Before prescribing AEL practitioners should consider: training experience, strength relative to body mass, the particular exercise, AEL application method, and the magnitude of both eccentric and concentric loads. Thus, the aims of this brief review are to describe: 1) neuromuscular and molecular constructs of AEL; 2) acute effects of AEL; 3) chronic effects of AEL; 4) loading considerations; 5) practical applications.
Adult ADHD vs Obsessive Compulsive Disorder in the DSM-V Era: A Case Report between challenging Differentiation and Comorbidity

ADHD (Attention Deficit Hyperactivity Disorder) is a complex pathological condition analysed mainly in children. In fact, ADHD in adults presents a more heterogeneous pattern of symptoms. Additionally, possible associated comorbidities can contribute to make the correct diagnosis in adults even more difficult. On top of the abovementioned complexity, coexistence of pathologies like ADHD and Obsessive Compulsive Disorder (OCD) appears to be not thoroughly investigated in adult population. In this regard, we present a case of a woman with OCD characterized by doubtful obsessions, accumulation compulsions, attention difficulties and deficit in executive functions. In particular, we aim to describe both the peculiarities of each disorder and the overlapping aspects between inattentive ADHD and OCD in adults. A good knowledge of the psychopathology of these two disorders is fundamental for differential diagnosis and exclusion of false comorbidity
A Systematic View of Model Leakage Risks in Deep Neural Network Systems

As deep neural networks (DNNs) continue to find applications in ever more domains, the exact nature of the neural network architecture becomes an increasingly sensitive subject, due to either intellectual property protection or risks of adversarial attacks. While prior work has explored aspects of the risk associated with model leakage, exactly which parts of the model are most sensitive and how one infers the full architecture of the DNN when nothing is known about the structure a priori are problems that have been left unexplored. In this paper we address this gap, first by presenting a schema for reasoning about model leakage holistically, and then by proposing and quantitatively evaluating DeepSniffer, a novel learning-based model extraction framework that uses no prior knowledge of the victim model. DeepSniffer is robust to architectural and system noises introduced by the complex memory hierarchy and diverse run-time system optimizations. Taking GPU platforms as a showcase, DeepSniffer performs model extraction by learning both the architecture-level execution features of kernels and the inter-layer temporal association information introduced by the common practice of DNN design. We demonstrate that DeepSniffer works experimentally in the context of an off-the-shelf Nvidia GPU platform running a variety of DNN models and that the extracted models significantly improve attempts at crafting adversarial inputs. The DeepSniffer project has been released in https://github.com/xinghu7788/DeepSniffer.
An Extended Sepic DC-DC Converter for Micro-Grid Based Photovoltaic (Pv) Applications.

Background Brain dural arteriovenous fistulas(bDAVFs) are anomalous connections between dural arteries and cerebral veins or sinuses. Cerebral venous thrombosis(CVT) often precedes or coincides with bDAVFs and is considered a risk factor for these vascular malformations. Recently, vaccine-induced thrombotic thrombocytopenia causing CVTs has been associated with COVID-19 vaccines. Concurrently with the start of massive vaccination in our region, we have observed a fivefold increase in the average incidence of bDAVFs. Objective To raise awareness of the potential involvement of COVID-19 vaccines in the pathogenesis of bDAVF. Methods A retrospective review of demographic, clinical, radiological, COVID-19 infection and vaccination data of patients diagnosed with bDAVFs between 2011-2021 was conducted. Patients were divided into two cohorts according to their belonging to pre- or post-COVID-19 vaccination times. Cohorts were compared for bDAVFs incidences and demographic and clinical features. Results Twenty-one bDAVFs were diagnosed between 2011- 2021, 7 of which were diagnosed in 2021. The mean age was 57.7 years, and 62% were males. All cases except one were treated; of them, 85% were exclusively managed with surgery. All treated cases were successfully occluded. The incidence in 2021 was significantly higher than that in the prevaccination period (1.72 vs 0.35/100,000/year;p=0.036; 95%Confidence Interval=0.09-2.66). Cohorts were not different in age, sex, hemorrhagic presentation, dural sinus thrombosis or presence of prothrombotic or cardiovascular risk factors. Conclusion The significant increase in the incidence of bDAVF following general vaccination policies against COVID-19 observed in our region suggests a potential correlation between these two facts. Our findings need confirmation from larger cohorts and further pathogenic research.
The Induced Pluripotent Stem Cells in Articular Cartilage Regeneration and Disease Modelling: Are We Ready for Their Clinical Use?

The development of induced pluripotent stem cells has brought unlimited possibilities to the field of regenerative medicine. This could be ideal for treating osteoarthritis and other skeletal diseases, because the current procedures tend to be short-term solutions. The usage of induced pluripotent stem cells in the cell-based regeneration of cartilage damages could replace or improve on the current techniques. The patient’s specific non-invasive collection of tissue for reprogramming purposes could also create a platform for drug screening and disease modelling for an overview of distinct skeletal abnormalities. In this review, we seek to summarise the latest achievements in the chondrogenic differentiation of pluripotent stem cells for regenerative purposes and disease modelling.
WRIST JOINT LOADING DURING THE ROUND-OFF SKILLS IN FEMALE GYMNASTICS

The aim of this study was to investigate key injury risk factors including wrist joint kinetics and kinematics in the second contact limb for both parallel and T-shape RO techniques. Seven international level female gymnasts performed 10 trials of round-off from a hurdle step to back handspring with “parallel” and “T” shape hand position. Two force plates were used to determine ground reaction forces. Eight infrared cameras were employed to collect the kinematic data. Ttest and effect size statistics established differences. Key findings of the current study are that in the parallel technique the wrist joint is exposing to higher axial compression load. Increased wrist joint dorsiflexion and radial deviation in the T-shape technique may indicate higher risk of wrist injury in gymnastics.
2′-O-Methylation of the second transcribed nucleotide within the mRNA 5′ cap impacts the protein production level in a cell-specific manner and contributes to RNA immune evasion

In higher eukaryotes, m7G-adjacent nucleotides undergo extensive modifications. Ribose of the first or first and second transcribed nucleotides can be subjected to 2’-O-methylation to form cap1 or cap2, respectively. Additionally, when the first transcribed nucleotide is adenosine, it can not only undergo 2’-O-methylation but can also be methylated at position N6 forming N6,2’-O-dimethyladenosine (m6Am). Recent studies have shed some light on the functions of cap1, showing that cap1 in mammalian cells plays a crucial role in distinguishing between ‘self’ and ‘non-self’ RNA during viral infection. Here, we attempted to understand the impact of other cap methylations on RNA-related processes. Therefore, we synthesized tetranucleotide cap analogs and used them for efficient co-transcriptional RNA capping during in vitro transcription. Using this tool, we found that 2’-O-methylation of the second transcribed nucleotide within the mRNA 5’ cap influences protein production levels in a cell-specific manner. The presence of this modification can strongly hamper protein biosynthesis or do not influence protein production levels. Interestingly, 2’-O-methylation of the second transcribed nucleotide as well as the presence of N6,2’-O-dimethyladenosine as the first transcribed nucleotide serve as determinants that define transcripts as ‘self’ and contribute to transcript escape from the host innate immune response. Additionally, cap methylation status does not influence transcript affinity towards translation initiation factor 4E or in vitro susceptibility to decapping by DCP2; however what we observe is resistance of RNA capped with cap2 to DXO-mediated decapping and degradation. Significance Statement Methylation of mRNA cap structure regulates protein biosynthesis in a cell-dependent manner. Among the three known m7G cap modifications, the 2’-O-methylation is dominant. 2’-O-methylation of the first transcribed nucleotide can boost protein production, whereas the same modification of the second transcribed nucleotide can strongly decrease translation. Interestingly, we show that in the JAWS II cell line, 2’-O-methylation of mRNA cap had a prominent impact on the composition of the protein interactome associated with the RNA bearing mentioned modifications. Further analysis revealed that 2’-O-methylation of the second transcribed nucleotide and N6-methylation of adenosine as the first transcribed nucleotide serve as determinants defining transcripts as ‘self’ and contribute to transcript escape from the host innate immune response.
Nitrogenous Altered Volcanic Glasses as Targets for Mars Sample Return: Examples From Antarctica and Iceland

Mars exploration is focused on seeking evidence of habitable environments and microbial life. Terrestrial glassy basalts may be the closest Mars‐surface weathering analog and observations increasingly indicate their potential to preserve biogeochemical records. The textures, major and trace element geochemistry, and N concentrations and isotopic compositions of subaerial, subglacial and continental lacustrine hyaloclastites from Antarctica, Iceland, and Oregon, respectively, were studied using micro‐imaging and chemical methods, including gas‐source mass spectrometry. Alteration by meteoric‐sourced waters occurred in circum‐neutral, increasingly alkaline low‐temperature conditions of ∼60°C–100°C (Iceland) and ∼60°C–170°C (Antarctica). Incompatible large ion lithophile element (LILE) enrichments compared to mid‐ocean ridge basalt (MORB) are consistent with more advanced alteration in Antarctic breccias consisting of heulandite‐clinoptilolite, calcite, erionite, quartz, and fluorapophyllite. Granular and tubular alteration textures and radial apatite represent possible microbial traces. Most samples contain more N than fresh MORB or ocean island basalt reflecting enrichment beyond concentrations attributable to igneous processes. Antarctic samples contain 52–1,143 ppm N and have δ15Νair values of −20.8‰ to −7.1‰. Iceland‐Oregon basalts contain 1.6–172 ppm N with δ15Ν of −6.7‰ to +7.3‰. Correlations between alteration extents, N concentrations, and concentrations of K2O, other LILEs, and Li and B, reflect the siting of secondary N likely as NH4+ replacing K+ and potentially as N2 in phyllosilicates and zeolites. Although much of the N enrichment and isotope fractionation presented here is not definitively biogenic, given several unknown factors, we suggest that a combination of textures, major and trace element alteration and N and other isotope geochemical compositions could constitute a compelling biosignature in samples from Mars' surface/near‐surface.
A Case Study of the Benefits of the Science Learning Partnerships in Early Years and Primary Education in England

This paper charts the recent history of the STEM Learning UK contracts with local Science Learning Partnerships (SLPs) and identifies what leadership has been made available to support the Early Years and Primary school sector. A case study approach is taken using ‘Super SLP’ hubs in England. Curriculum Hubs exist in core subject areas such as maths, English, science and computing. They have recently been expanded to include Behaviour Hubs. This forms the current DfE strategy of Teaching School Hubs (TSHs), i.e., to offer system support and a full career-length support for all stages of teacher-career and leadership development. This paper charts the changes to the Early Years (EY) and Primary teacher support networks, in science particularly, and examines what they provide and how this can be improved, and discusses, through session evaluation and feedback, what teachers have appreciated the most.
Phylogenetic approach for identification and life cycles of Puccinia (Pucciniaceae) species on Poaceae from northeastern China

About 300 species of Puccinia on Poaceae have been reported globally. However, these species can be difficult to identify because of morphological similarities and difficulties of host plant identifications. The presence of many cryptic species is also suspected. Based on about 150 specimens on Poaceae and about 50 related specimens of spermogonial and aecial stages, all collected in northeastern China, a phylogenetic approach was conducted to clarify their identification and life cycles. In phylogenetic analyses 25 clades among specimens on Poaceae were detected. Each clade detected in phylogeny was interpreted as an independent species, although many clades were morphologically similar to each other. After comparative morphology with species previously reported, 17 species including three first records in China (P. cerienthes-agropyrina, P. coronati-agrostidis, P. coronati-hordei) were identified, and eight species (P. ampliaticoronata, P. digitaticoronata, P. eleganticoronata, P. elymi-albispora, P. oncospora, P. pileiformis, P. protuberanticoronata, P. ramificatacoronata) are described as new. In uredinial and telial stages, the host range of above 25 species was variable ranging from one host plant species to several host species, sometimes involving different grass genera. Thus, a phylogenetic approach is more suitable for species identifications of Puccinia on Poaceae rather than relying on rust morphology and host plant identification. Life cycle relations for 15 spermogonial and aecial species were also clarified by phylogenetic analyses. It is also suspected that grass rusts can be differentiated to species based on spermogonial and aecial stages on same or related host plants.
Investigating the contribution of community empowerment policies to successful co-production- evidence from Scotland

ABSTRACT Although frequently perceived as a ‘woolly’ policy concept and a means to reduce public service delivery costs, co-production can lead to increased quality and efficiency of services. In this paper, we explore the contribution of a community empowerment policy to co-production processes. Analysing empirical findings from a mixed-method, longitudinal study through the lens of Myers et al.’s (2017) Theory of Change, the paper develops a model of a successful co-production process. We show that changes in working practices and shifts in power can create friction between co-producing actors. By critiquing specific policies, we inform future co-production research, policy, and practice.
The Effect of Complementary Measurement and Evaluation Techniques on Academic Achievement: A Meta-Analysis Study

Bu araştırma, tamamlayıcı ölçme ve değerlendirme tekniklerinin akademik başarıya etkisini araştırmayı amaçlamaktadır. Bu araştırma bir meta-analiz çalışması olup 40 araştırma çalışmasından (makale, tez ve tam metin sunumlar) oluşmaktadır. Meta-analiz süreci için rastgele etkiler modeli seçilmiştir. Çalışmada ele alınan üç çalışmada tamamlayıcı ölçme ve değerlendirme tekniklerinin akademik başarı üzerinde olumsuz etkisi bulunurken, 40 çalışmada tamamlayıcı ölçme ve değerlendirme tekniklerinin akademik başarı üzerinde olumlu etkisi bulunmaktadır. Rastgele etkiler modeli kullanılarak hesaplanan genel etki +1.080'dir. Bu araştırma sonucunda tamamlayıcı ölçme ve değerlendirme teknikleri akademik başarı üzerinde geniş bir etkiye sahiptir.