Miracle-dz/UniFAR-FTUs huggingface dataset:
The Cathode Choice for Commercialization of Sodium‐Ion Batteries: Layered Transition Metal Oxides versus Prussian Blue Analogs

With the unprecedentedly increasing demand for renewable and clean energy sources, the sodium‐ion battery (SIB) is emerging as an alternative or complementary energy storage candidate to the present commercial lithium‐ion battery due to the abundance and low cost of sodium resources. Layered transition metal oxides and Prussian blue analogs are reviewed in terms of their commercial potential as cathode materials for SIBs. The recent progress in research on their half cells and full cells for the ultimate application in SIBs are summarized. In addition, their electrochemical performance, suitability for scaling up, cost, and environmental concerns are compared in detail with a brief outlook on future prospects. It is anticipated that this review will inspire further development of layered transition metal oxides and Prussian blue analogs for SIBs, especially for their emerging commercialization.
The synergistic actions of hydrolytic genes reveal the mechanism of Trichoderma harzianum for cellulose degradation

Bioprospecting genes and proteins related to plant biomass degradation is an attractive approach for the identification of target genes for biotechnological purposes, especially genes with potential applications in the biorefinery industry that can enhance second-generation ethanol production technology. Trichoderma harzianum is a potential candidate for cellulolytic enzyme prospection and production. Herein, the enzymatic activities, transcriptome, exoproteome, and coexpression networks of the T. harzianum strain CBMAI-0179 were examined under biomass degradation conditions. We used RNA-Seq to identify differentially expressed genes (DEGs) and carbohydrate-active enzyme (CAZyme) genes related to plant biomass degradation and compared them with the genes of strains from congeneric species (T. harzianum IOC-3844 and T. atroviride CBMAI-0020). T. harzianum CBMAI-0179 harbors strain- and treatment-specific CAZyme genes and transcription factors. We detected important proteins related to biomass degradation, including β-glucosidases, endoglucanases, cellobiohydrolases, lytic polysaccharide monooxygenases, endo-1,4-β-xylanases and β-mannanases, in the exoproteome under cellulose growth conditions. Coexpression networks were constructed to explore the relationships among the genes and corresponding secreted proteins that act synergistically for cellulose degradation. An enriched cluster with degradative enzymes was described, and the subnetwork of CAZymes revealed strong correlations among the secreted proteins (AA9, GH6, GH10, GH11 and CBM1) and differentially expressed CAZyme genes (GH45, GH7, AA7 and GH1). Our results provide valuable information for future studies on the genetic regulation of plant cell wall-degrading enzymes. This knowledge can be exploited for the improvement of enzymatic reactions in biomass degradation for bioethanol production. Key points Different biotechnological approaches were used to understand the mechanism of cellulose degradation of Trichoderma spp. T. harzianum CBMAI-0179 is a potential candidate for the production of cellulolytic enzymes. Coexpression networks revealed genes and proteins acting synergistically for cellulose hydrolysis.
The Effect of Evening Primrose Oil on the Intensity of Postpartum Blues Among Primiparous Females: A Double-blind, Randomized, Controlled Clinical Trial

Background: The most vulnerable time to develop mood disorders such as sadness, depression, and psychosis is the postpartum period. Postpartum blues is the most common mood disorder and can endanger the relationships between mother, child, and family, and in case of lack of appropriate treatment can cause irreparable damages. Objectives: The current study aimed at investigating the effect of evening primrose oil on the intensity of postpartum blues among primiparous females. Methods: The current double-blind, randomized, controlled clinical trial was conducted from December 2012 to November 2013 on 132 primigravida females referred to health centers of Ahvaz, Iran. They were randomly divided into two groups of 66 to receive a daily dose of 1 g of evening primrose oil capsules (intervention group) or similar placebo capsules (control group) from the beginning of the 37 weeks of pregnancy up to 2-weeks postpartum. Females in both groups were asked to complete the Edinburg questionnaire on the days 4,10, and 14 postpartum. Data were analyzed using the t-test, Chi-square test, and repeated measures, and P < 0.05 was considered significant. Results: There was a statistically significant difference (P= 0.0 001) between the two groups regarding the severity of the postpartum blues (the severity in the intervention group was less than that of the placebo group, P = 0.0001). The score of Edinburgh questionnaire was significantly less in the intervention group compared with that of the control group on the days 4,10 (P = 0.0001), and 14 of postpartum (P = 0.01) (P = 0.014). The averages of Edinburgh score in the intervention group was significantly less compared with those of the control group on the days 4 (10.5 +/- 0.57 vs. 13.3 +/- 3.28; P = 0.0001), 10 (11.2 +/- 1.22 vs. 14.9 +/- 3.6; P = 0.001), and 14 postpartum (11.7 +/- 1.3 vs. 13.05 +/- 2.6; P = 0.08). Conclusions: The use of evening primrose oil effectively reduced the severity of postpartum blues.
BBF Deceleration Down‐Tail of X < −15 RE From MMS Observation

We report the direct observation on bursty bulk flow (BBF) deceleration down‐tail of X < −15 RE by MMS satellite. Two typical events are presented in the paper. In the first event on 05 June 2018, MMS1 is located at X ~ −16.1 RE and records four individual bursty flows (BFs). Each burst flow has distinctly lower velocity than the preceding one. Accompanying with the decelerated BFs, the Bz/Bx continuously increases/decreases. Simultaneous Vx‐decrease and Bz‐increase are in coincidence with the scenario of the local BBF deceleration and formation of the magnetic pileup region. In the second event on 03 July 2017, MMS stays in the neutral sheet of X ~ −24.5 RE, and encounters similar BBF deceleration process. For both events, the decelerated BF series exhibit prominent medium‐energy ion component (2–10 KeV). Analyses show enhanced parallel current (J//) and Kinetic Alfvénic wave (KAW) emitting during the BF intervals. The strength of the emitted KAW has a clear tendency to decay with the BBF decreasing. Power spectra density analysis confirms the substantial Joule dissipation during the BBF deceleration, both J// and J⊥. Combined analyses support BBF dissipation via Joule heating as well as KAW emitting. Finally, we propose a possible mechanism on the BBF deceleration, i.e., “collision” with the tailward flow.
ANTIMICROBIAL AND ANTIRADICAL PROPERTIES OF HAMMADA SCOPARIA (POMEL) ILJIN

Background: Hammada scoparia (Pomel) Iljin (HS), is commonly used by traditional healers in Morocco against microbial and fungal infections. We studied antimicrobial, antifungal and antiradical effects of organic extracts in vitro in order to confirm traditional utilization after phytochemical screening. Materials and methods: Aerial parts of HS have been extracted by hydro-distillation using Clevenger-type apparatus, and the chemical composition was realized by Gas Chromatography coupled with Mass Spectroscopy (GC/MS). The antioxidant activity has been evaluated using DPPH test, while the antimicrobial tests of HS extract were conducted on twenty-eight bacterial strains and antifungal on twelve fungal strains. Results: Chemical characterization of HS essential oils (EO) confirmed the presence of carvacrol (82,28%), p-cymene (2,52%), γ-terpinene (2,18%) and Z-caryophyllene (2,04%). Antimicrobial tests of HS extract showed a moderate antibacterial activity without antifungal effect. In addition, HS exhibited a very powerful antiradical activity with IC50 = 1,2 mg/ml compared to that of ascorbic acid (IC50 = 0,5 mg/mL) and butylated hydroxyanisole (0,8 mg/mL). Conclusion: To our knowledge, this is the first demonstration that HS directly inhibits the growth of microorganisms in vitro, and further validates its traditional use as an antiseptic by traditional Moroccan healers.
ROLE OF CREDIBILITY OF PHENOMENA IN ATTITUDE TOWARD ADVERTISING

Having a huge transformation in conjunction with transition from Web 1.0 to Web 2.0, the Internet gave rise to emergence of micro-celebrities called phenomena and led the concept of influencer marketing which uses these celebrities as the basic decision makers to gain popularity among today’s marketing activities. Many studies reveal that the phenomena (influencers) acting as “senders” in online marketing activities influence their followers and activate them in desired direction. In the present study conducted in this direction, the impact of the credibility, attractiveness, expertise and trustworthiness of the phenomena on the attitude toward advertising was examined. The research was done on university students. The correlation analysis made in the study to reveal if there is a significant correlation between the credibility dimensions of attractiveness, expertise and trustworthiness of the phenomena and the attitude toward advertising shows that there are significant correlations between all three dimensions and attitude toward advertising (r=0.46, p<0.01 for attractiveness; r=0.26; p<0,01 for expertise; r=0.31; p<0,01 for trustworthiness). Furthermore, the results of the research show that only the attractiveness dimension of the phenomena among their credibility dimensions (attractiveness, expertise, trustworthiness) has a significant impact on the attitude toward advertising.
A DEALG methodology for prediction of effective customers of internet financial loan products

Abstract It is becoming more crucial nowadays for researchers to objectively utilize reasonable and effective methods to choose a key customer index and analyze a wealth of data, with the aim of setting up precision marketing of Internet financial products. This paper thus considers pre-process data via DEA and adds the DEA efficiency value into the logistic regression model, which can improve accuracy of the basic logistic regression model. This novel data analytics approach, termed DEALG, significantly enhances the customer response rate of Internet loan products according to its results. The goal is to effectively identify those customers who are more likely to show their interests on the loan products in order to achieve the goal of precision marketing, thus reducing supply-side costs. The results of the DEALG method are very promising, and in the real world it can be applied as an actual marketing method like sending text messages to potential clients. Finally, the results show that this method can generate high profits for the Internet financial industry.
FUNCTIONAL CHARACTERIZATION OF THE YEAST RNA BINDING PROTEIN MIP6

RNA binding proteins (RBPs) participate in virtually every step of gene expression, demonstrating a potential role as a quality control system contributing to RNA homeostasis. One of the proteins with an essential role in mRNA export in yeast is the evolutionary conserved Mex67 transporter. Although Mex67 binds to RNAs, it requires adaptor proteins to interact with quality-controlled mRNAs and undergo export through the nuclear pore complex. During heat shock, Hsf1 and Msn2/Msn4 transcription factors produce stress-responsive mRNAs. The export of Hsf1-dependent mRNAs depends on direct interaction with Mex67, without quality control mechanisms. However, we know less regarding the export of Msn2/Msn4-dependent transcripts, although various relatively unstudied RBPs may participate in this process. Previous yeast two-hybrid assays revealed an interaction between Mex67 and the putative RBP Mip6. Mip6 contains four RNA recognition motifs (RRMs) and has been described as a modulator of mRNA metabolism during sporulation. In this thesis, we report the functional characterization of Mip6 under optimal and stressful growth conditions through a study of the functional interaction with the essential exporter Mex67, its mRNA targets, and the required elements for its subcellular localization. Mip6 directly interacts with the ubiquitin-associated domain of Mex67 through tryptophan-442 of Mip6 RRM4, whose mutation leads to the slow growth of yeast cells in vivo. Mip6 shuttles between the nucleus and the cytoplasm in a Mex67-dependent manner and concentrates in cytoplasmic foci in response to insult by various stressors. Mip6 copurifies with Pab1 in stress granules (SGs), and cells lacking MIP6 display altered Pab1-SGs behavior. Confocal microscopy studies established that deletion of the Mip6 RRMs leads to Mip6 nuclear retention. Moreover, the export of Mip6 is also regulated by a Crm1-independent Nuclear Export Signal (NES) in RRM4 that is controlled by the karyopherin Msn5. Photoactivatable ribonucleoside-enhanced crosslinking and immunoprecipitation (PAR-CLIP) experiments demonstrated enriched Mip6 binding to Msn2/Msn4 dependent transcripts under stress-free conditions; however, Mip6 enrichment changes during heat shock showing a preferential binding to ribosomal protein genes (RPGs). Consistent with PAR-CLIP results, MIP6 deletion and the mutation of tryptophan-442 augment the expression levels of Msn2/Msn4 targets (HSP12 and CTT1). Deletion of both MIP6 and the RRP6 nuclear exosome component further increases HSP12 and CTT1 levels. These results reveal a novel role for Mip6 in mRNA homeostasis through direct interaction with Mex67. We envision a model in which the initial interaction of Mip6 with RNA contributes to the Mex67- and/or NES-dependent export of Mip6. This transport helps to regulate the levels of Msn2/Msn4-dependent mRNAs under stress-free conditions. However, in response to stressors, Mip6 accumulates in SGs aid the repression of RPG mRNAs.
Distribution and genetic diversity of Echinochloa oryzicola resistant to ALS and ACCase inhibitors in Korea

Abstract The emerging incidence of herbicide resistance in weeds is a serious problem for rice production in Korea. Echinochloa oryzicola has been reported as multiple resistant to acetolactate synthase (ALS) and acetyl-CoA carboxylase (ACCase) inhibitors. The objectives of this study were to monitor distribution and genetic diversity of E. oryzicola suspected to have herbicide resistance to ALS and ACCase inhibitors in Korean paddy fields by using simple sequence repeat (SSR) marker. The occurrence and propagation of herbicide-resistant E. oryzicola were found at serious levels in Jeonbuk and Chungnam provinces. The worst affected regions were Gimje, Gunsan, and Iksan of Jeonbuk province. Herbicide resistance levels of E. oryzicola populations to ALS inhibitors were much greater than those to ACCase inhibitors. SSR analysis showed very low genetic differentiation between ALS and ACCase on resistance and susceptibility. While genetic diversity has been confirmed by province scale, herbicide-resistant E. oryzicola was found to be spreading severely throughout Korea. Thus, it is necessary to monitor herbicide resistance regularly and develop a long-term strategy of integrated pest management for infested paddy fields.
The experiences of family caregivers of persons with physical disabilities

Almost everyone will experience a form of impairment or disability some or other time in their lives. Different types of impairment could occur at any given moment. For example, parents might find out their baby was born with cerebral palsy, a person might be injured in a motor vehicle accident or a person who suffered a stroke is left paralysed on the one side. This disability can persist for years or even life-long, requiring family members to act as informal caregivers. Living with a person with a disability can have significant effects on the family members. This unique shared experience can affect all aspects of family functioning in both a positive and a negative manner. Many previous research studies have investigated the needs of persons with disabilities but very few have focused on the family members who care for them. The goal of this study was to gain a better understanding of the experiences of family caregivers of persons with physical disabilities. This goal was achieved by discussing the experiences of family caregivers of persons with physical disabilities from previous studies. The ecological perspective was utilised to explore the different social support needs and services of family caregivers of persons with physical disabilities. An analysis was done of the experiences of family caregivers of persons with physical disabilities regarding their support needs and the barriers they experience. Finally, relevant recommendations were made on how to improve social support to family caregivers of persons with physical disabilities. It was decided to make use of Bronfenbrenner’s ecological perspective when investigating the experiences of family caregivers of persons with physical disabilities. This perspective, which sees families as social environments, identifies four systems of a person’s social environment: the micro-, meso-, exoand macrosystem. The study also used the Parents’ Supportive Care Needs Framework that identifies social, emotional, practical, physical, psychological and informational needs as parts of supportive needs of parents. The research study used a qualitative approach with some elements of a quantitative approach with regard to identifying particulars of the participants. It used a combination of descriptive and exploratory research design. The reasoning of the research study was both deductive and inductive. The data collection was done by means of a semi-structured interview that was done with a sample of 20 participants of family caregivers of persons with physical disabilities Stellenbosch University https://scholar.sun.ac.za
Deepening extinction in a virtual reality treatment for fear of heights

15 Introduction . 17 Method . 23 Results . 29 Discussion. 58 Conclusion . 66 Chapter 2: Empirical paper. 67 Abstract . 68. 68 Introduction . 70 Current study . 80 Method . 81 Results . 99 Discussion. 106 Conclusion . 113 Chapter 3: Integration, impact and dissemination . 115 Integration. 116 Impact and dissemination . 122
High-sensitivity photoacoustic gas detector by employing multi-pass cell and fiber-optic microphone.

A high-sensitivity photoacoustic (PA) spectroscopy (PAS) system is proposed for dual enhancement from both PA signal excitation and detection by employing a miniaturized Herriott cell and a fiber-optic microphone (FOM). The length of the optical absorption path of the PA cell is optimized to ∼374 mm with 17 reflections. The volume of the PA cell is only 622 µL. The FOM is a low-finesse fiber-optic Fabry-Pérot (FP) interferometer. The two reflectors of the FP cavity are formed by a fiber endface and a circular titanium diaphragm with a radius of 4.5 mm and a thickness of 3 µm. A fast demodulated white-light interferometer (WLI) is utilized to measure the absolute FP cavity length. The acoustic responsivity of the FOM reaches 126.6 nm/Pa. Several representative PA signals of trace acetylene (C2H2) are detected to evaluate the performance of the trace gas detector in the near-infrared region. Experimental results show that the minimum detectable pressure (MDP) of the FOM is 3.8 µPa/Hz1/2 at 110 Hz. The noise equivalent minimum detection concentration is measured to be 8.4 ppb with an integration time of 100 s. The normalized noise equivalent absorption (NNEA) coefficient is calculated as 1.4×10-9 cm-1·W·Hz-1/2.
Does the human skin microbiome adapt to antibiotic exposure

Staphylococcus epidermidis is a substantial element of the healthy human skin microflora and can become pathogenic to cause infections, for example, septicaemia and endocarditis. The effects of long-term sub-lethal exposure to antibiotics on the skin microbiota are unknown. How does antibiotic adaptation affect the ability of S. epidermidis to interact with host immune systems, inhibit pathogens and keep a healthy microflora? This project aims to characterise five S. epidermidis bacteria samples isolated from the skin, before and after exposure to antibiotics thus comparing their antibiotic susceptibility pattern (disc diffusion assay), biofilm formation (crystal violet microtitre plate assay) and microbial virulence (G. mellonella infection assay). Serially passaged antibiotic-adapted strains were also assessed for the following characteristics: colony and cell morphology, cross-resistance (to other antibiotics), growth rate and competitive fitness ability. S. epidermidis parent strains were firstly susceptible to antibiotics such as erythromycin and doxycycline, and later formed adaptive resistance. Erythromycin adapted strains were found to be resistant to erythromycin and cross- resistant to doxycycline based on both disk diffusion assay and MIC results. Doxycycline adapted strains formed resistance to doxycycline based on both disk diffusion assay and MIC results. Significant differences (p <0.05) were observed in the mean relative biofilm units and G. mellonella infection assay survival rates of antibiotic-adapted strains of S. epidermidis. Erythromycin adapted strain had significantly enhanced fitness advantage (w value- 1.35, p value- 0.0427) and were significantly virulent (p-value of 0.0065) when compared to the parent strain. Doxycycline adapted strain showed significantly lower fitness advantage (w value- 0.38, p-value 0.0005) yet, they were significantly virulent (p-value of 0.0059) in comparison to the parent strain. These findings highlight the implications of adaptive resistance to antibiotics in the treatment of S. epidermidis infections, and therefore necessitate the development of more sophisticated future treatments for bacterial infections. It is important for the private and public healthcare sectors worldwide to invest in the advancement of new anti-infectives to combat the growing antibiotic resistance.
Longevity in elderly Greek migrants to Australia may be explained by adherence to a traditional Greek Mediterranean diet

Between 1988 and 1991 data were collected on diet, health and lifestyle on 818 people aged 70 and over from countries/cultures experiencing longevity: Swedes, Greeks, Australians (Greeks and Anglo-Celts) and Japanese. This was known as the Food Habits in Later Life study (FHILL). Subjects from these 5 cohorts were followed up for 5–7 years to determine survival status and to examine the effect of diet and lifestyle variables on longevity. The FHILL study was the first to develop a score which captured the key features of a traditional plant-based Mediterranean diet pattern (MDPS). A higher score (i.e greater adherence to this dietary pattern) improved overall survival in both Greek and non-Greek elderly reducing the risk of death by 50% after 5–7 years. Of the 5 cohorts studied, first generation elderly Greeks in Australia had the lowest risk of death, even though they had the highest rates of obesity and other cardiovascular disease (CVD) risk factors (developed in the early years of migration with the introduction of energy dense foods). This was called a “Greek migrant Morbidity Mortality Paradox”. Greek migrants appeared to be “getting away” with these CVD risk factors because of their continued adherence to a Mediterranean diet, especially legumes. This paper reviews a) the findings from the FHILL study b) other studies on Greek migrants to Australia c) clinical studies investigating possible mechanisms. We propose that the Mediterranean diet may be operating to reduce the risk of death and attenuate established CVD risk factors by beneficially altering the gut microbiome.