Miracle-dz/UniFAR-FTUs huggingface dataset:
STRUCTURAL DESIGN AND ANALYSIS OF ELLIPTIC CYCLOCOPTER ROTOR BLADES

A cyclocopter propelled by the cycloidal blade system is a new concept of VTOL vehicle which has excellent hovering characteristics and low speed forward flight capability. The cycloidal blade system, which can be described as a horizontal rotary wing, offers powerful thrust levels and a unique ability to change the direction and the magnitude of the thrust almost instantly. In this paper, rotor blades of unmanned cyclocopter with 4 rotors are designed and structural analysis is carried out. Elliptical blades are fabricated of carbon and glass composite materials to reduce relatively high centrifugal force. Rotor design variables are determined through CFD analysis, and structural analysis by MSC.NASTRAN is carried out for the designed characteristics. Parametric study of composite rotor hub arm is carried out about the dynamic mode behaviors according to the variations of composite lay-up and joint condition.
Modeling and Analysis of a Feedback-Controlled Active Magnetic Levitation System Using COMSOL Multiphysics Finite Element Software

Magnetic levitation systems have been studied in the context of high-speed transportation as maglev trains, high speed machinery as magnetic bearings, and other similar engineering applications. In this paper, a three dimensional arbitrary shaped object is modeled and analyzed through COMSOL. Mechanically the levitated object has three degrees of freedomtwo along the x and y axes and the third one rotational about the z axis. The x, y and Ө are the controlled variables, while the control input is the current fed to the field coil placed above the object. A basic requirement in simulation and analysis of the system is computation of the electromagnetic fields and forces for various positions of the disc. For levitation systems, especially those involving more complicated geometries, this task has to be carried out through numerical FE or FE – BE simulation. In this work it was achieved using the basic COMSOL multiphysics software.
Learning of Spatial Invariances for Object-Ground Separation

Whenever a biological plausible model should learn object representations in a real world scenario, the model tends to learn connections not only to features of the learned object but also to some features of the background. We present a learning algorithm that is capable of learning background-independent object representations due to temporal differences in the background. The algorithm is based on a previous one, used for learning the object representations in the visual attention model of Beuth and Hamker [2]. As the representations in this model have encoded a black background among the object, the model performed very well when localizing an object before a black-background, but only averagely when the object is placed in a real-world scene. To address such problems, we advance the learning algorithm to obtain backgroundindependent object representations, and adapt the V1-layer to generate responses similar to their biological counterparts.
Hardware-in-the-Loop emulator for a hydrokinetic turbine

Hydroelectric power has proven to be an efficient and reliable form of renewable energy, but its impact on the environment has long been a source of concern. Hydrokinetic turbines are an emerging class of renewable energy technology designed for deployment in small rivers and streams with minimal environmental impact on the local ecosystem. Hydrokinetic technology represents a truly clean source of energy, having the potential to become a highly efficient method of harvesting renewable energy. However, in order to achieve this goal, extensive research is necessary. This paper presents a Hardware-in-the-Loop emulator for a run-of-the-river type hydrokinetic turbine. The HIL system uses an ABB ACS800 drive to control an induction machine as a significant means of replicating the behavior of the real turbine. The induction machine is coupled to a permanent magnet synchronous generator and the corresponding load. The ACS800 drive is controlled through the software system, which comprises of the hydrokinetic turbine real-time simulation through mathematical modeling in the LabVIEW programming environment running on a NI CompactRIO (cRIO) platform. The advantages of this method are that it can provide a means for testing many control configurations without requiring the presence of the real turbine. This paper contains the basic principles of a hydrokinetic turbine, particularly the run-of-the-river configurations along with the experimental results obtained from the HIL system.
Updated genetic analyses based on mitochondrial and microsatellite DNA indicated no substructure of the ‘ O ’ stock common minke whale in the western North Pacific

This study examined the genetic population structure of ‘O’ stock common minke whale in the western North Pacific based on mitochondrial DNA control region sequencing (487bp) and microsatellite DNA (16 loci). Samples used in the tests of homogeneity were obtained during the surveys of the JARPN and JARPNII in sub-areas of the Pacific side of Japan between 1994 and 2014 (n= 2,071 for microsatellite; n= 2,070 for mtDNA). Whales were assigned to the ‘O’ stock by the analysis of STRUCTURE presented in Pastene et al. (2016: SC/F16/JR38). Tests based on both genetic markers and different grouping of the samples showed no evidence of sub-structuring in the ‘O’ stock common minke whale in the Pacific side of Japan. A simulation exercise showed that the statistical power of the homogeneity test was high. In addition, a Discriminant Analysis of Principal Components (DAPC) based on the total samples used in Pastene et al. (2016: SC/F16/JR38) showed clear differentiation between J and O stock whales but no evidence of sub-structuring within the O stock samples. Consequently the results of this study suggested a low plausibility for the hypothesis of sub-division of the O stock common minke whale into OW and OE.
Esquema hı́brido para renderizações foto-realistas com mapas de iluminação

This paper introduces a new approach to the problem of direct illumination in physically-based rendering of 3D scenes using illumination maps captured from real environments. We developed a system that takes advantage of the best features of the current solutions to the problem: namely, the approximation of illumination maps through directional lights; and stochastic sampling of the light maps. Our framework is flexible and can be used with most rendering programs. Keywords—Three-dimesional Graphics and Realism, Sampling, Rendering, Environment Maping, Importance Sampling, Deterministic Sampling. Resumo—Neste artigo apresentamos uma nova abordagem para o problema de iluminação na renderização foto-realista com mapas de iluminação provenientes de cenas reais. Desenvolvemos um sistema que extrai o melhor das duas principais abordagens existentes para o problema: aproximação dos mapas de iluminação com luzes direcionais e amostragem estocástica dos mapas. O Esquema Hı́brido proposto pode ser utilizado tanto com métodos de iluminação direta quanto com algoritmos de iluminação global. Nossa proposta vem complementar e consolidar as técnicas tradicionais, pois permite utilizá-las separadamente ou combiná-las para tratar o problema de amostragem das fontes luminosas durante a renderização com iluminação real.
THEORETICAL FRAMEWORK ON MANAGEMENT ACCOUNTING AND ORGANISATIONAL CHANGE

Prior research in management accounting examined various relationships between organisational change and management accounting system (MAS). The purpose of this paper is to provide a theoretical framework by using contingency theory and institutional perspective abouthow organisational and MAS changes take place. This paper contributes to theoretical argumentation on the interrelationship between management accounting and organisational change and how such changes might help in achieving overall success of the organisation.
Annual Precise Time and Time Interval ( PTTI ) Systems and Applications Meeting 257 A Voice Time Monitoring and Recording Sub-System for the Telephone Speaking Clock

In this research, the TSMS was extended to monitor the output of the TSSC on dedicated telephone line, called TSMS_A1. From this sub-system, an interrupt circuit with a Linux kernel driver was developed for capturing the rising edge of the on-time tone which is from TSSC output to produce an interrupt event. Through this event, the TSMS’ controller was trigged immediately to measure the time error and record the announced voice program into an audio file. The audio recording procedures and a raw file converting from PCM (Pulse Code Modulation) into Waveform Audio File Format (WAVE) were studied. In the system design, Unified Modeling Language (UML) notation tools, such as user case diagram and activity diagram were used to express basic concepts of the system requirements and interactive behaviors.
Segmentation of Argumentative Texts with Contextualised Word Representations

The segmentation of argumentative units is an important subtask of argument mining, which is frequently addressed at a coarse granularity, usually assuming argumentative units to be no smaller than sentences. Approaches focusing at the clause-level granularity, typically address the task as sequence labeling at the token level, aiming to classify whether a token begins, is inside, or is outside of an argumentative unit. Most approaches exploit highly engineered, manually constructed features, and algorithms typically used in sequential tagging – such as Conditional Random Fields, while more recent approaches try to exploit manually constructed features in the context of deep neural networks. In this context, we examined to what extend recent advances in sequential labelling allow to reduce the need for highly sophisticated, manually constructed features, and whether limiting features to embeddings, pre-trained on large corpora is a promising approach. Evaluation results suggest the examined models and approaches can exhibit comparable performance, minimising the need for feature engineering.
Genetic and Morphological Diversity in Aphis gossypii Glover (Hemiptera: Aphididae) in the Pacific Basin

Abstract:Aphis gossypii Glover is cosmopolitan pest aphid, known to be represented by host-associated lineages. Although it is widespread in the Pacific Basin, there has been no assessment of this species in this region. We examined patterns of morphological variation within and among populations collected across hosts and islands using multivariate morphometric analyses. Genetic variation was determined using microsatellite flanking region sequences and mitochondrial cytochrome oxidase subunit 1. This study confirmed the existence of genetically distinct host-associated lineages. We found that host plant affects morphological expression and therefore morphological criteria cannot be used to identify lineages. Comments are provided on the origin and maintenance of these host lineages and implications for management of this important pest aphid species.
Relationship Between Sleep Apnea and Coronary Artery Calcium in Patients With Ischemic Stroke

Study Objectives: Coronary artery disease is considered to be the major cause of death amongst patients with ischemic stroke. The coronary artery calcium (CAC) score is related not only to sleep-disordered breathing, but also with future risk of cardiovascular mortality. We investigated the association between the severity of sleep-disordered breathing and CAC score in patients with ischemic stroke. Methods: We included 32 patients who underwent coronary multichannel computed tomography and polysomnography (within 2 years of the stroke event) amongst the patients admitted to our clinic due to acute ischemic stroke. We investigated vascular risk factors, polysomnography findings, and sleep questionnaire scores, and their relationships with the CAC score. Results: All patients were found to have sleep apnea of any degree, and 23 (72%) had severe sleep apnea. Twenty-three (72%) patients had a positive CAC score. Higher CAC scores were associated with elevated respiratory disturbance index (RDI), apnea index, oxygen desaturation index, and STOP-BANG test scores. Multivariate analysis after adjusting for potential confounding factors revealed independent relationships between the CAC score and the RDI (ß [SE] = 5.3 [2.1], p = 0.01), oxygen desaturation index (ß [SE] = 6.8 [2.8], p = 0.02), and STOP-BANG test score (ß [SE] = 90.3 [37.7], p = 0.02). Conclusion: Our findings indicate a relationship between coronary atherosclerotic burden measured by the CAC score and the severity of sleep apnea. Performing polysomnography could be useful for investigating the severity of hidden coronary artery disease among these patients. Brief Summary Current Knowledge/Study Rationale: The effect of sleep apnea on coronary artery disease in patients with ischemic stroke has not been explored. We investigated the relationship between sleep apnea, its related characteristics and the coronary artery calcium score in patients with stroke. Study Impact: Our findings reveal a close relationship between the atherosclerosis-related burden measured by the coronary artery calcium score and the severity of sleep apnea that persisted after adjusting for confounding variables related to the risk of coronary artery disease. Proper detection and treatment of sleep apnea might mitigate the risk of future coronary events in patients with ischemic stroke.
Cysteine-Rich Peptide Fingerprinting as a General Method for Herbal Analysis to Differentiate Radix Astragali and Radix Hedysarum

Species misidentification and adulteration are major concerns in authenticating herbal medicines. Radix Astragali (RA), the roots of Astragalus membranaceus, is a traditional herbal medicine used for treating diabetes. However, it is often substituted by Radix Hedysarum (RH), the roots of Hedysarum polybotrys from the same plant family Fabaceae, which possesses different bioactivities. Current authentication methods, focusing on the chemical composition differences of herbal medicines based on small molecules, have limitations when these chemical markers are found in many species. Herein, we describe a rapid and general method using matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS), coupled with multivariate analyses to differentiate herbal medicines. We used cysteine-rich peptide (CRP) fingerprinting, a method that exploits an underexplored chemical space between 2 to 6 kDa and which is populated by highly stable CRPs. To show the generality of the method, we screened 100 medicinal plant extracts and showed that CRP fingerprints are unique chemical markers. In addition, CRP fingerprinting was many-fold faster than the conventional authentication method using ultra-performance liquid chromatography (UPLC). Multivariate analyses showed that it has comparable classification accuracy as UPLC fingerprinting. Together, our findings revealed that CRP fingerprinting coupled with multivariate analyses is a rapid and general method for authentication and quality control for natural products in medicinal plants.
A Robust 8-Gene Prognostic Signature for Early-Stage Non-small Cell Lung Cancer

Background: The current staging system is imprecise for prognostic prediction of early-stage non–small cell lung cancer (NSCLC). This study aimed to develop a robust prognostic signature for early-stage NSCLC, allowing classification of patients with a high risk of poor outcome and specific treatment decision. Method: In the present study, a comprehensive genome-wide profiling analysis was conducted using a retrospective pool of early-stage NSCLC patient data from the previous datasets of Gene Expression Omnibus (GEO) including GSE31210, GSE37745, and GSE50081 and The Cancer Genome Atlas (TCGA). Cox proportional hazards models were implemented to determine the association between gene expression levels and overall patient survival in each dataset. The common genes among all datasets were selected as candidate prognostic genes. A risk score model was developed and validated using four independent datasets and the entire cohort. The Kaplan-Meier with log-rank test was used to assess survival difference. Results: A univariate Cox proportional hazards regression analysis for each dataset showed that a total of 2280 genes in GSE31210, 762 genes in GSE37745, 871 genes in GSE50081, and 666 genes in TCGA were identified as candidate protective genes, while overall 2131 genes in GSE31210, 913 in GSE37745, 1107 in GSE50081, and 997 in TCGA were identified as candidate risky genes. There were 8 common genes associated with overall survival, including 7 mRNA and 1 lncRNA. By using the Step-wise multivariate Cox analysis, an 8-gene prognostic signature (CDCP1, HMMR, TPX2, CIRBP, HLF, KBTBD7, SEC24B-AS1, and SH2B1) for early-stage NSCLC was developed. Patients in the high-risk group had shorter overall survival than those in the low-risk group. Multivariate regression and stratified analysis suggested that the prognostic power of the 8-gene signature was independent of other clinical factors. Furthermore, the 8-gene signature achieved AUC values of 0.726, 0.701, 0.725 and 0.650 in GSE31210, GSE37745, GSE50081 and TCGA, respectively. Moreover, the combination of the 8-gene signature and the stage resulted to a better patient classification for survival prediction and treatment decision. Conclusion: This study developed a robust gene signature with great value for prognostic prediction in early-stage NSCLC, which may contribute to patient classification and personalized treatment decisions.
Expression of Oncofetal Antigen 5T4 in Murine Taste Papillae

Background: Multicellular taste buds located within taste papillae on the tongue mediate taste sensation. In taste papillae, taste bud cells (TBCs), such as taste receptor cells and taste precursor cells, and the surrounding lingual epithelium including epithelial progenitors (also called taste stem/progenitor cells) are maintained by continuous cell turnover throughout life. However, it remains unknown how the cells constituting taste buds proliferate and differentiate to maintain taste bud tissue. Based on in situ hybridization (ISH) screening, we demonstrated that the oncofetal antigen 5T4 (also known as trophoblast glycoprotein: TPBG) gene is expressed in the adult mouse tongue. Results: In immunohistochemistry of coronal tongue sections, 5T4 protein was detected at a low level exclusively in the basal part of the lingual epithelium in developing and adult mice, and at a high level particularly in foliate papillae and circumvallate papillae (CVPs). Furthermore, immunohistochemistry of the basal part of CVPs indicated that the proliferation marker PCNA (proliferating cell nuclear antigen) co-localized with 5T4. 5T4 was strongly expressed in Krt5+ epithelial progenitors and Shh+ taste precursor cells, but weakly in mature taste receptor cells. The number of proliferating cells in the CVP was higher in 5T4-knockout mice than in wild-type (WT) mice, while neither cell differentiation nor the size of taste buds differed between these two groups of mice. Notably, X-ray irradiation enhanced cell proliferation more in 5T4-knockout mice than in WT mice. Conclusion: Our results suggest that 5T4, expressed in epithelial progenitors (taste stem/progenitor cells), and taste precursor cells, may influence the maintenance of taste papillae under both normal and injury conditions.
Interneuron Development Is Disrupted in Preterm Brains With Diffuse White Matter Injury: Observations in Mouse and Human

Preterm brain injury, occurring in approximately 30% of infants born <32 weeks gestational age, is associated with an increased risk of neurodevelopmental disorders, such as autism spectrum disorder (ASD) and attention deficit hyperactivity disorder (ADHD). The mechanism of gray matter injury in preterm born children is unclear and likely to be multifactorial; however, inflammation, a high predictor of poor outcome in preterm infants, has been associated with disrupted interneuron maturation in a number of animal models. Interneurons are important for regulating normal brain development, and disruption in interneuron development, and the downstream effects of this, has been implicated in the etiology of neurodevelopmental disorders. Here, we utilize postmortem tissue from human preterm cases with or without diffuse white matter injury (WMI; PMA range: 23+2 to 28+1 for non-WMI group, 26+6 to 30+0 for WMI group, p = 0.002) and a model of inflammation-induced preterm diffuse white matter injury (i.p. IL-1β, b.d., 10 μg/kg/injection in male CD1 mice from P1–5). Data from human preterm infants show deficits in interneuron numbers in the cortex and delayed growth of neuronal arbors at this early stage of development. In the mouse, significant reduction in the number of parvalbumin-positive interneurons was observed from postnatal day (P) 10. This decrease in parvalbumin neuron number was largely rectified by P40, though there was a significantly smaller number of parvalbumin positive cells associated with perineuronal nets in the upper cortical layers. Together, these data suggest that inflammation in the preterm brain may be a contributor to injury of specific interneuron in the cortical gray matter. This may represent a potential target for postnatal therapy to reduce the incidence and/or severity of neurodevelopmental disorders in preterm infants.
MdGGT1 Impacts Apple miR156 Precursor Levels via Ontogenetic Changes in Subcellular Glutathione Homeostasis

The vegetative phase change in flowering plants is controlled by microRNA156 (miR156) under transcriptional regulation. However, the developmental signals upstream of miR156 are not well understood. The glutathione/glutathione disulfide (GSH/GSSG) ratios and GSH levels decline significantly during phase change, which is consistent with miR156 expression in apple (Malus domestica Borkh.). Here, we found that the content of protein conjugated glutathione was remarkably higher in chloroplasts and nuclei of adult than juvenile phase apple hybrids. The decrease in miR156 expression was most relevant to the activities of serine acetyltransferase (SAT) and soluble γ-glutamyl transpeptidase (GGT), and the expressions of MdGGT1 or MdSATs. Transgenic apples over-expressing MdMIR156 or miR156-mimetic (MIM156) did not alter MdGGT1 expression or the soluble GGT activity. Inhibition of GGT activity with serine-borate complex or acivicin led to significant reduction in GSH content, the GSH/GSSG ratio, and the expressions of MdMIR156a5, MdMIR156a12, and miR156. Depletion of GSH with diethyl maleate without altering GGT activity caused a dramatic decrease in the expression of MdMIR156a5, MdMIR156a12, and miR156. Manipulating GGT activity and GSH homeostasis by transgenic over-expressing or RNAi MdGGT1 increased or decreased MdMIR156a5 and MdMIR156a12 levels, respectively. These data provided novel evidence that MdGGT1 participates in transcriptional level of transcription regulation of miR156 precursors during ontogenesis. HIGHLIGHTS - MdGGT1 affects thiol redox status and indirectly participates in the regulation of miR156 expression during vegetative phase change.