Miracle-dz/UniFAR-FTUs huggingface dataset:
A case of bilateral scapholunate advanced collapse in a Romano‐British skeleton from Ancaster

Degenerative joint disease (DJD) of the wrist (radiocarpal joint) is relatively uncommon in modern Western populations, usually occurring as a result of trauma. Clinically, scapholunate advanced collapse (SLAC) is the most common pattern of DJD seen in the wrist, involving a progressive destruction of the radioscaphoid and then the capitolunate joint. There is only one report of SLAC wrist in the palaeopathological literature. In this paper, we report on another ancient case of bilateral SLAC wrists, found in a Roman skeleton from Ancaster, Lincolnshire. The osteological analysis of ANC 01 217 skeleton determined that this was an elderly but robust adult (50+ years) male, about 165 cm tall. The bones were sufficiently well preserved to allow inspection of joint surfaces. The bones were also radiographed. Osteoarthritis (OA) was diagnosed according to accepted palaeopathological criteria: principally the presence of eburnation on a joint surface. Eburnation was found at the articular surfaces of the wrist joint and numerous intercarpal joints bilaterally. The pattern of joints affected matched modern clinical descriptions of SLAC wrist. Radiographic changes characteristic of OA were identifiable at the wrist joint, but not at the intercarpal joints. This case proves that SLAC wrist is identifiable in dry bones, but the discrepancy between the observational and radiographic findings highlights the problems encountered when attempting to compare disease in archaeological versus modern populations. Copyright © 2006 John Wiley & Sons, Ltd.
Availability of New Medicaid Patient Appointments and the Role of Rural Health Clinics.

OBJECTIVE To examine the willingness to accept new Medicaid patients among certified rural health clinics (RHCs) and other nonsafety net rural providers. DATA SOURCES Experimental (audit) data from a 10-state study of primary care practices, county-level information from the Area Health Resource File, and RHC information from the Center for Medicare and Medicaid Services. STUDY DESIGN We generate appointment rates for rural and nonrural areas by patient-payer type (private, Medicaid, self-pay) to then motivate our focus on within-rural variation by clinic type (RHC vs. non-RHC). Multivariate linear models test for statistical differences and assess the estimates' sensitivity to the inclusion of control variables. DATA COLLECTION The primary data are from a large field study. PRINCIPAL FINDINGS Approximately 80 percent of Medicaid callers receive an appointment in rural areas-a rate more than 20 percentage points greater than nonrural areas. Importantly, within rural areas, RHCs offer appointments to prospective Medicaid patients nearly 95 percent of the time, while the rural (nonsafety net) non-RHC Medicaid rate is less than 75 percent. Measured differences are robust to covariate adjustment. CONCLUSIONS Our study suggests that RHC status, with its alternative payment model, is strongly associated with new Medicaid patient acceptance. Altering RHC financial incentives may have consequences for rural Medicaid enrollees.
Edema and Congestive Heart Failure from Thiazolidone Insulin Sensitizers—Excess Sodium Reabsoption in the Collecting Duct Collecting Duct-Specific Deletion of Peroxisome Proliferator-Activated Receptor γ Blocks Thiazolidinedione-Induced Fluid Retention. Proc Nat Acad Sci U S A 102: 9406–9411, 2005

Thiazolidinediones Expand Body Fluid Volume through PPARγ Stimulation of ENaC-Mediated Renal Salt Absorption Guan Y, Hao C, Cha DR, Rao R, Lu W, Kohan DE, Magnuson MA, Redha R, Zhang Y, Breyer MD. Nat Med 11: 861–867, 2005 Thiazolidones are peroxisome proliferator-activated receptor γ (PPAR
Can a More User‐Friendly Medicare Plan Finder Improve Consumers’ Selection of Medicare Plans?

OBJECTIVE To evaluate the efficacy for consumers of two potential enhancements to the Medicare Plan Finder (MPF)-a simplified data display and a "quick links" home page designed to match the specific tasks that users seek to accomplish on the MPF. DATA SOURCES/STUDY SETTING Participants (N = 641) were seniors and adult caregivers of seniors who were recruited from a national online panel. Participants browsed a simulated version of the MPF, made a hypothetical plan choice, and reported on their experience. STUDY DESIGN Participants were randomly assigned to one of eight conditions in a fully factorial design: 2 home pages (quick links, current MPF home page) × 2 data displays (simplified, current MPF display) × 2 plan types (stand-alone prescription drug plan [PDP], Medicare Advantage plan with prescription drug coverage [MA-PD]). PRINCIPAL FINDINGS The quick links page resulted in more favorable perceptions of the MPF, improved users' understanding of the information, and increased the probability of choosing the objectively best plan. The simplified data display resulted in a more favorable evaluation of the website, better comprehension of the displayed information, and, among those choosing a PDP only, an increased probability of choosing the best plan. CONCLUSIONS Design enhancements could markedly improve average website users' understanding, ability to use, and experience of using the MPF.
The Mental Health Parity and Addiction Equity Act Evaluation Study: Impact on Mental Health Financial Requirements among Commercial “Carve‐In” Plans

OBJECTIVE Did mental health cost-sharing decrease following implementation of the Mental Health Parity and Addiction Equity Act (MHPAEA)? DATA SOURCE Specialty mental health copayments, coinsurance, and deductibles, 2008-2013, were obtained from benefits databases for "carve-in" plans from a national commercial managed behavioral health organization. STUDY DESIGN Bivariate and regression-adjusted analyses compare the probability of use and (conditional) level of cost-sharing pre- and postparity. An interaction term is added to compare differential levels of pre- and postparity cost-sharing changes for plans that were and were not already at parity pre-MHPAEA. FINDINGS Controlling for employer/plan characteristics, MHPAEA is associated with higher intermediate care copayments ($15.9) but lower outpatient ($2.6) copayments among in-network-only plans. Among plans with in- and out-of-network benefits, MHPAEA is associated with lower inpatient ($23.2) and outpatient ($2.5) copayments, but increases in inpatient and intermediate in-network and out-of-network coinsurance (about 1 percentage point). Among the few plans not at parity pre-MHPAEA, changes in use and level of cost-sharing associated with MHPAEA were more dramatic. CONCLUSION Mixed evidence that MHPAEA led to more generous mental health benefits may stem from the finding that many plans were already at parity pre-MHPAEA. Future policy focus in mental health may shift to slowing growth in cost-sharing for all health services.
Meaningful Use and Hospital Performance on Post‐Acute Utilization Indicators

OBJECTIVES To examine trends in hospital post-acute utilization indicators and to determine whether improvement in these indicators is associated with attesting to meaningful use (MU). DATA SOURCES Medicare claims-based, repeated measures on 30-day hospital-wide all-cause readmission and emergency department (ED) utilization rates for 160 short-stay hospitals (2009-2012); Medicare EHR Incentive Program Payments files (2011-2012); and other hospital and market data. STUDY DESIGN Interrupted time series with concurrent comparison group. PRINCIPAL FINDINGS Propensity score-weighted multilevel models for change demonstrate that 30-day readmission rates (unadjusted) fell from 13.4 percent in 2009 to 12.1 percent in 2012. Similarly, 30-day ED utilization declined from 18.9 percent to 17.3 percent during the same period. However, MU and non-MU hospitals were indistinguishable vis-à-vis performance. Controlling for hospital and market characteristics, MU was unrelated to 30-day readmission. In contrast, 30-day ED utilization deteriorated. CONCLUSIONS Hospitals with MU Stage 1 designation did not show significantly higher improvement on post-acute utilization compared to their counterparts without. To achieve gains in quality and safety, potentially associated with EHRs, and to advance care coordination and patient engagement, the regulators should strengthen accountability by linking comprehensive, outcomes-based performance measures to specific MU objectives.
Sensitivity analysis of parameters affecting image processing of high pressure gaseous jet images

ARTICLE INFO Digital image processing is one of efficient methods that is adopted today for the determination of fuel spray characteristics in internal combustion engines. The imaging method and the images quality are two important factors that influence the accuracy of results. In this paper, an edge finding method was employed for processing of the Schlieren image of the gaseous jet, and sensitivity analysis has been conducted to investigate effects of the edge finding method threshold, the experiments scale factor and the level of the blur and the noise of images on image processing results. A method based on the Otsu method has been proposed also for finding the dynamic threshold for Schlieren jet images. Results showed that the sensitivity of the jet tip velocity to the edge finding method threshold was low (in the valid range of the threshold), but in regions that the jet tip velocity was low, this sensitivity was as high as 14%. The sensitivity of the jet tip penetration to the blur level of images was less than 2%, while the tip velocity was more sensitive to the blur content of images, and the blur with the standard deviation of 4 could led to 28% error in the tip velocity. © Iranian Society of Engine (ISE), all rights reserved. Article history: Received: 18 February 2014 Accepted: 16 March 2014
Interoperability: What Is It, How Can We Make It Work for Clinicians, and How Should We Measure It in the Future?

As the result of the federal incentive program, electronic health records have been widely adopted in the United States, with levels of adoption exceeding 90 percent in both the inpatient and outpatient settings (Henry et al. 2016). However, it is clear that health information exchange has lagged behind (Holmgren andAdler-Milstein 2017). Further, we have been disappointed to date in the lack of impact that this technology has had on health care delivery. Adoption of electronic health records did not consistently improve quality according to data gathered after Stage 1 of meaningful use (MU) (Kern et al. 2013; Samal et al. 2014). Transition from Stage 1 to Stage 2 of MU did not consistently produce the expected improvements in quality (Levine et al. 2017). There are many reasons that quality is not getting better so far with the new technology, but one is that health information exchange performance has lagged far behind performance onmost otherMU objectives (Holmgren and Adler-Milstein 2017). Interoperability has been defined by the Institute for Electrical and Electronics Engineering in the IEEE Standard Computer Dictionary as “the ability of two or more systems or components to exchange information and to use the information that has been exchanged” (1991). That is different from health information exchange (HIE), which merely requires an ability to share information electronically. Notably, you can have HIE without true interoperability—the latter requires an ability to use shared data, and not just exchange information. Both adoption of EHRs—which implies electronic collection of information—and interoperability—suggesting you can move data around when ©Health Research and Educational Trust DOI: 10.1111/1475-6773.12852 DEBATE-COMMENTARY
Cationic Surfactant Sorption to a Vermiculitic Subsoil via Hydrophobic Bonding.

Organoclays formed in soil from the addition of the cationic surfactant hexadecyltrimethylammonium (HDTMA) can effectively immobilize organic contaminants dissolved in water. The adsorption and desorption of HDTMA in a subsoil was studied to determine the stability of surfactant-soil clay complexes as affected by surfactant retention mechanism. We found that HDTMA was initially adsorbed by cation exchange in the interlayer, causing extensive clay aggregation. As the loading increased, HDTMA adsorbed to the external surfaces of aggregates via both cation exchange and hydrophobic bonding, the latter causing positive charge development on surfaces and ultimately clay dispersion. When the equilibrium concentration of HDTMA reached the critical micelle concentration, no further HDTMA adsorption occurred. Desorption of HDTMA was more significant when the HDTMA retention mechanism was hydrophobic bonding. HDTMA adsorption can be affected by cation type as well as the type and concentration of electrolytes, and these factors can be used to minimize the undesirable effects of hydrophobic bonding such as clay dispersion and HDTMA desorption.
Transaction Costs, Suboptimal Termination and Default Probabilities

The same option-based methodology now commonly used to value mortgages and their termination features also can be applied to calculate the probabilities that mortgage default will occur. This paper pursues that idea, and furthermore, enriches the idealized option-based approach by introducing both transaction costs and "suboptimal" termination. These latter features capture the individual considerations that cause a mortgage holder's actions to differ from what rationality would indicate based solely on the market value of the mortgage. These features are of considerable importance if the results of options-based models are to be made comparable to those calculations of default probabilities occurring in the empirical literature. Copyright American Real Estate and Urban Economics Association.
Private firms run a third of CCGs’ schemes to screen GP referrals

At least 24 clinical commissioning groups across England are paying private companies to screen referrals from GPs to specialist care, The BMJ has found. The BMJ ’s investigation found that two fifths of CCGs that responded to its requests for information use a referral management system of some kind,1 despite previous evidence casting doubt on the effectiveness of such systems.2 The analysis—the first to track the number of referral management schemes in operation since CCGs were established in 2013—comes afte r The BMJ recently reported details of North Durham CCG’s decision to …
Drought impact on wheat yield in Oklahoma and Nebraska: A remote sensing perspective

The frequent occurrences of drought in the Great Plains of United States have led to significant crop loss. Timely monitoring of drought-induced agricultural impacts, especially at a large scale from remote sensing, is of great importance for ensuring food security. Following the authors' prior drought impact work in Kansas, based on MODIS data, this study investigated the impacts of drought on winter wheat in Oklahoma (OK) and Nebraska (NE) during the main growing season at 8-day intervals, both at the state and agricultural statistics district level, and then explored the spatial variability of drought impacts. Despite some variability, drought shows generally increasing impacts during winter wheat main growing season for both states, reaching the peak around Mid-Late April in OK and Mid-Late May in NE during their corresponding vegetative peaks. As compared to NE, winter wheat has higher planting density in OK and drought shows more significant impacts in OK.
mtDNAprofiler: A Web Application for the Nomenclature and Comparison of Human Mitochondrial DNA Sequences ,

Mitochondrial DNA (mtDNA) is a valuable tool in the fields of forensic, population, and medical genetics. However, recording and comparing mtDNA control region or entire genome sequences would be difficult if researchers are not familiar with mtDNA nomenclature conventions. Therefore, mtDNAprofiler, a Web application, was designed for the analysis and comparison of mtDNA sequences in a string format or as a list of mtDNA single‐nucleotide polymorphisms (mtSNPs). mtDNAprofiler which comprises four mtDNA sequence‐analysis tools (mtDNA nomenclature, mtDNA assembly, mtSNP conversion, and mtSNP concordance‐check) supports not only the accurate analysis of mtDNA sequences via an automated nomenclature function, but also consistent management of mtSNP data via direct comparison and validity‐check functions. Since mtDNAprofiler consists of four tools that are associated with key steps of mtDNA sequence analysis, mtDNAprofiler will be helpful for researchers working with mtDNA. mtDNAprofiler is freely available at http://mtprofiler.yonsei. ac.kr.
Genetic evidence of PTPN22 effects on chronic lymphocytic leukemia.

To the editor: The recent article by Negro et al represents a thorough investigation into the effect of Lyp, the gene product of PTPN22 , on BCR signaling in the pathogenesis and progression of chronic lymphocytic leukemia (CLL). [1][1] This study shows that increased Lyp enhances Akt, a serine/
Genotypic Polymorphisms of Hepatitis B Virus Provide Useful Information for Estimating Geographical Origin or Place of Long‐term Residence of Unidentified Cadavers

Increasing numbers of unidentified cadavers are a major problem. We have developed a new method for providing identification information that can determine the geographical origin or place of long‐term residence of unidentified cadavers based on genotypic polymorphisms of hepatitis B virus (HBV) known to correlate with their geographical distribution. PCR of serum samples detected HBV DNA from 4 (3.9%) of 102 randomly selected Japanese forensic cadavers.
The “Bestie di Satana” Murders

In recent years, satanic groups have been responsible for various types and degrees of crimes. We report the case of a number of murders committed in Italy by a group of young people calling themselves the “Bestie di Satana”. Forensic psychiatric assessment of the members of a satanic sect charged with the crime revealed that all the young people had a fragile, immature personality, a very low level of education and were socially disadvantaged. The trial of the members of the “Bestie di Satana” sect was concluded with the verdict of deliberate murder, and all the members were given long jail sentences. This report should lead us to explore social and cultural responses to juvenile satanism, statistically shown to be a relatively rare phenomenon but with a high criminal potential.
Manual of Histological Demonstration Techniques

By reading, you can know the knowledge and things more, not only about what you get from people to people. Book will be more trusted. As this manual of histological demonstration techniques, it will really give you the good idea to be successful. It is not only for you to be success in certain life you can be successful in everything. The success can be started by knowing the basic knowledge and do actions.
Analysis of change in anti‐acetylcholine receptor antibody and effect on myasthenia gravis symptoms by adjusting tacrolimus dosage according to the blood concentration

Since its introduction, tacrolimus has been widely used in myasthenia gravis (MG) patients. However, the correlation between the blood concentration level of the drug, the change in anti‐acetylcholine receptor (AChR) antibody and the effect of the drug has not been reported.
A VLSI architecture for high-performance, low-cost, on-chip learning

The motivation for the X1 architecture described was to develop inexpensive commercial hardware suitable for solving large, real-world problems. Such an architecture must be systems oriented and flexible enough to execute any neural network algorithm and work cooperatively with existing hardware and software. The early application of neural networks must proceed in conjunction with existing technologies, both hardware and software. Using state-of-the-art technology and innovative architectural techniques, the author's architecture approaches the speed and cost of analog systems while retaining much of the flexibility of large, general-purpose parallel machines. The author has aimed at a particular set of applications and has made cost-performance tradeoffs accordingly. The goal is an architecture that could be considered a general-purpose microprocessor for neurocomputing
Predictors of Intentions to Have Pelvic Examinations Among a UK Sample of Young Asian and non-Asian Women

ABSTRACT. Objectives: Women delay gynecological care for various reasons, including practical difficulties and self-consciousness about having health professionals view their genitals. Methods: Experiences of and intentions to have pelvic examinations, attitudes toward female genitals, and genital self-image were investigated in young Asian and non-Asian women. Results: Past experience of having had pelvic screening and fears about screening were the strongest predictors of intentions to have pelvic examinations in the future. Asian women were significantly less likely to have had a pelvic examination compared with non-Asian women, but there were no group differences in attitudes toward female genitals, genital self-image, or intentions to have pelvic examinations.
Continuous analogs to discrete dynamical systems with application to modeling biological response

A general condition is formulated which establishes conditions for deriving a system of first-order differential equations which qualitatively match the behavior of a class D of discrete dynamical systems defined on a cross product {0, 1, 2, . , mi -1}n, i=1, . , n, where {mi} is a set of integers. The qualitative matching is defined as a homology condition between two dynamical systems. Five definitions and four theorems establish the basis for a procedure for the construction of continuous analogs which are defined by first-order differential equations, thus embedding the discrete system into a continuous one. The proposed approach is demonstrated by applying a model of generalized immune response to cognitive habit release mechanisms involved in phobia
Recovery of Spray Paint Traces from Clothing by Beating

Manual recovery of spray paints from textiles using a microscope, the routine method in many laboratories, is often laborious. Beating the clothing with a plastic rod, the routine method used for recovery of glass traces within the authors’ laboratory, is proposed as an alternative. The efficiency of the method was evaluated by spray tests with fluorescent paint. In these tests, paint particles in the acquired debris samples, as well as those remaining on the textiles, were investigated. The results show that beating is an efficient way to recover and concentrate paint particles. A good efficiency for jeans fabric and rough knitwear is reported. The results appeared to be less satisfactory for smooth woven fabric. Application of the method in casework was effective for graffiti paints as well as for flaked car paint.
Child Suicide in the North of Portugal

Suicide in children is a rare finding and is probably motivated by acts of impulsiveness. This study aims to contribute to the characterization of child suicide in a forensic perspective in the Portuguese population. Data of forensic autopsies from 2004 to 2012 related to suicide victims under 18 years were reviewed. A total of 17 cases, with a male predominance (64.7%) and a mean age of 15.24 ± 1.348 for both genders, were registered. The leading suicide method was hanging (35.3%), and a suicide note was found in 41.2%. Psychological autopsy proved to be useful in promoting a better understanding of these incidents and their antecedents. This study also offers useful information, namely the implied risk factors, for future programs of suicide research and prevention.