Miracle-dz/UniFAR-FTUs huggingface dataset:
EVIDENCE OF SOCIAL STRUCTURE OF A NEOLITHIC COMMUNITY IN SVODÍN , SOUTHWEST SLOVAKIA

The period after initial development of Neolithic society in Central Europe, known as the Post-LBK era, is marked by an influx of new cultural stimuli from the South and the emergence of formalization in monumental architecture, resulting in a cultural diversification while maintaining significant common traits across different regions. An important part of understanding the process of this change is understanding the development of social complexity during the transition. This study addresses this question by examining variations in burial rite coinciding with the age or sex of the deceased or the spatial distribution of 106 graves from the Lengyel Culture settlement in Svodín, dated around 4800 cal BC. The concept of exceptionality rather than richness of burials is introduced. It is based on the composition and spatial distribution of inventories within graves and contrary to the traditional deductive approach does not depend on prior selection of attributes of prestige. Principal Component Analysis is used to assess exceptionality based on ceramic shapes, decoration and non-ceramic grave goods. Resampling tests using a Monte Carlo algorithm are employed to assess the significance of connection of specific attributes with exceptional burials and age, sex or spatial groups. This approach enables us to study social differences in regions and time periods where prestigious materials such as metal are not yet present. New conclusions are drawn about social stratification in the Post-LBK era and confronted with results of existing studies dealing with status and prestige. The image of a vertically differentiated society with middle aged men assuming the highest rank in the community emerges, showing complex social relations both between and within different kinships on the settlement. Observations of diachronic development of social differences indicate a gradually evolving society, foreshadowing the emergence of elites in the following Aeneolithic period.
Microbiology STUDY OF CD 4 T-CELL COUNT AND HIV VIRAL LOAD IN HIV PATIENTS UNDERGOING ANTIRETROVIRAL THERAPY VISITING NATIONAL PUBLIC HEALTH LABORATORY , TEKU , KATHMANDU , NEPAL

Infection with Human Immunodeficiency Virus (HIV) is a global burden affecting large population throughout the world. Regular monitoring of CD4 cell count and viral load is necessary to evaluate treatment success in patients undergoing antiretroviral treatment (ART). This study was carried out with the aim of determining the CD4 T-cell counts and viral load on patients in antiretroviral therapy. The cross sectional descriptive study was conducted on 175 HIV infected individuals on ART who visited at National Public Health Laboratory (NPHL), Teku, Kathmandu, Nepal for their viral load estimation. The study was carried over a period of six month from June 2013 to November 2013. Three to five ml of venous blood was collected from each patient and processed in parallel to determine CD4 T-cell count (Rotar gene) using QAigen kit. Prevalence of HIV was found higher in sexually active age group 15-49 years (82.86%) and males were predominant (54.86%). Regarding CD4 and viral load, correlation was statistically significant (P=0.008). 60% of the patients had undetectable viral load and 24% were suffering from AIDS as they had CD4 count less than or equal to 200 copies/μl. Mean viral load in female was found drastically lower (13938 copies/ml) than in male (37526 copies/ml) while CD4 counts were not significantly different (336 for male and 396 for female). In HIV patients under ART, the progression to AIDS is slower but regular monitoring of CD4 count and viral load is necessary to predict the stage of infection and to find viral burden in the patient.
Using the UTAUT Model to Determine the Factors Affecting the Technology Acceptance in Judicial System Environment

The implementation of e-government technology to support both user and organization enables both to perform better by facilitating and decision-making processes. This paper addresses the problem of how to determine the factors that influence employees to accept and use technology implemented in Judicial System institutions in developing countries focusing on acceptance technology theories. The research model employed in this study is based on the Unified Theory of Acceptance and Use of Technology (UTAUT). The study will be undertaken via quantitative method by distributing questionnaires to target respondents. The intended method of data analysis describes the objectives to be included later, including a variable analysis followed by the intended quantitative analysis. Finally, the expected outcome of this study is to identify the possible issues which occur when implementing e-government in a local law environment.
Gene Expression in Antifungal Resistant and Susceptible Isolates of Candida albicans

The expression of five resistance genes was measured by RT-PCR after treatment of C. albicans with both FLU and TRB. The results indicated that Candida drug resistant gene CDR1 was expressed in susceptible and resistant isolates. However, Candida drug resistant gene CDR2, Candida multidrug resistant gene CaMDR1 and ergosterol resistant gene ERG11 were up regulated in only resistant C. albicans against FLU and TRB. Fluconazole resistant gene FLU1 in C. albicans not expressed at all antifungal treatments.
13 Migration Strategies towards the Digital Manufacturing Automation

Today, industries are facing new market demand and customer requirements for higher product personalization, without jeopardizing the low level of production costs achieved through mass production. The joint pursuit of these objectives of personalization and competitiveness on costs is quite difficult for manufacturers that have traditional production systems based on centralized automation architectures. Centralized control structures, in fact, do not guarantee the system adaptability and flexibility required to achieve increasing product variety at shorter time-to-market. In order to avoid business failure, industries need to quickly adapt their production systems and migrate towards novel production systems characterized by digitalization and robotization. The objective of this chapter is to illustrate a methodological approach to migration that supports decision makers in addressing the transformation. The approach encompasses the initial assessment of the current level of manufacturing digital maturity, the analysis of priorities based on the business strategy, and the development of a migration strategy. Specifically, this chapter presents an innovative holistic approach to develop a migration
NF-k B is essential for epithelial-mesenchymal transition and metastasis in a model of breast cancer progression

The transcription factor NF-kB is activated in a range of human cancers and is thought to promote tumorigenesis, mainly due to its ability to protect transformed cells from apoptosis. To investigate the role of NF-kB in epithelial plasticity and metastasis, we utilized a wellcharacterized in vitro/in vivo model of mammary carcinogenesis that depends on the collaboration of the Ha-Ras oncoprotein and TGF-b. We show here that the IKK-2/IkBa/NFkB pathway is required for the induction and maintenance of epithelial-mesenchymal transition (EMT). Inhibition of NF-kB signaling prevented EMT in Ras-transformed epithelial cells, while activation of this pathway promoted the transition to a mesenchymal phenotype even in the absence of TGF-b. Furthermore, inhibition of NF-kB activity in mesenchymal cells caused a reversal of EMT, suggesting that NF-kB is essential for both the induction and maintenance of EMT. In line with the importance of EMT for invasion, blocking of NF-kB activity abrogated the metastatic potential of mammary epithelial cells in a mouse model system. Collectively, these data provide evidence of an essential role for NF-kB during distinct steps of breast cancer progression and suggest that the cooperation of Rasand TGF-b–dependent signaling pathways in late-stage tumorigenesis depends critically on NFkB activity. Article Oncology
Enhancing dependence-based prefetching for better timeliness, coverage, and practicality

This dissertation proposes an architecture that efficiently prefetches for loads whose effective addresses are dependent on previously-loaded values (dependence-based prefetching). For timely prefetches, the memory access patterns of producing loads are dynamically learned. These patterns (such as strides) are used to prefetch well ahead of the consumer load. Different prefetching algorithms are used for different patterns, and different algorithms are combined on top of dependence-based prefetching scheme. The proposed prefetcher is placed near the processor core and targets L1 cache misses, because removing L1 cache misses has greater performance potential than removing L2 cache misses. For higher coverage, dependence-based prefetching is extended by augmenting the dependence relation identification mechanism, to include not only direct relations (y = x) but also linear relations (y = ax + b) between producer (x) and consumer (y) loads. With these additional relations, higher performance, measured in instructions per cycle (IPC), can be obtained. We also show that the space overhead for storing the patterns can be reduced by leveraging chain prefetching and focusing on frequently missed loads. We specifically examine how to capture pointers in linked data structures (LDS) with pure hardware implementation. We find that the space requirement can be reduced, compared to previous work, if we selectively record patterns. Still, to make the prefetching scheme generally applicable, a large table is required for storing pointers. So we take one step further in order to eliminate the additional storage need for pointers. We propose a mechanism that utilizes a portion of the L2 cache for storing the pointers. With this mechanism, impractically huge on-chip storage for pointers, which is sometimes a total waste of silicon, can be removed. We show that storing the prefetch table in a partition of the L2 cache outperforms using the L2 cache conventionally for benchmarks that benefit from prefetching.
Photonic device design flow : from mask layout to device measurement

Mask layout design is an important part in silicon photonic device design flow; the space used and the quality of the mask directly affect the cost of fabrication and quality of the outcome. To effectively minimize time spent on drawing masks, fixing design violations, and reducing unused spacings between each structure, we use effective approaches in the mask design process to ensure the listed criteria are met. Using the PCell and the hierarchy drawing methods, GDS files that contain different device parameters can be generated efficiently. As a result, direct GDS modeling efficiency is improved. An experimental setup that is capable of obtaining high quality measurement data is critical to device measurement. The concept of an automated measurement station can effectively reduce work needed from the experimenter while providing quality results. With the implemented fiber-to-fiber and fiber array automated measurement station, multi-device measurement can be set up to run automatically in minutes whereas traditional manual measurement stations require one’s presence and constant attention. In this thesis, we have illustrated several mask drawing approaches and showed the drawing steps of two masks in detail. We have described two automated experimental setups, fiber-to-fiber and fiber array, in detail and included various measurement results to show the capabilities of these two stations.
Time-domain method for tracking dispersive channels in OFDM systems

In this paper we address the problem of channel estimation in the case of single-input single-output (SISO) OFDM systems. The proposed technique is based on time-domain channel estimation whereas equalization is performed in frequency domain. The time-domain channel estimation/tracking stage is based on the Kalman filter. Due to the nature of OFDM transmission, equalization in frequency domain is done using single-tap zero-forcing of MMSE techniques. Improvements over existing methods are demonstrated in simulations using time and frequency selective channels.
Principles Of Heat Transfer In Porous Media

Thank you very much for downloading principles of heat transfer in porous media. Maybe you have knowledge that, people have look hundreds times for their chosen books like this principles of heat transfer in porous media, but end up in malicious downloads. Rather than enjoying a good book with a cup of coffee in the afternoon, instead they cope with some harmful bugs inside their desktop computer. principles of heat transfer in porous media is available in our digital library an online access to it is set as public so you can get it instantly. Our book servers saves in multiple locations, allowing you to get the most less latency time to download any of our books like this one. Kindly say, the principles of heat transfer in porous media is universally compatible with any devices to read.
A Code Generation Example for Event-B:A Shared Channel with Concurrent Read/Writers

We present an example involving processes reading and writing to a shared channel. A channel may have at most one reader reading, and at most one writer writing at any one time; however a number of processes may be waiting to read from, or write to, the channel. In our most abstract model data is transferred as a block in a single atomic step. A write event constitutes moving a block from a writing process to a channel buffer; and a read event constitutes moving a block from a channel buffer to a reader. The atomicity of the read and write activity is altered in the refinement - we introduce blocks that are made up of packets, and each packet is written to the channel individually. This allows the reader to begin reading as soon as there is data in the channel - without the writer having to complete the data transfer. We continue with an overview of our implementation notation (OCB), and show the implementation level specification for the concurrent read/writers example. We then present details of the implementation level refinement that results from the translation of the OCB model into Event-B, and also show details of the source code generated by the Java translator.
Extending bach: A Family of Libraries for Real-time Computer-assisted Composition in Max

The bach library is a package for Max meant to bring symbolic music representation and computer-aided composition in a real-time environment (Agostini & Ghisi, 2013, 2015). In this article, we introduce a more ambitious project: situating the bach library inside a wider family of tools dealing with real-time computer-aided composition in Max, which we call the ‘bach family’. We give an overview of its core member (bach) and of its second member (cage: a high-level library of ready-made modules). We introduce its third member (dada: a library of non-standard user interfaces, currently under development), and discuss future perspectives and ideas.
Dynamic Views of the Fc Region of Immunoglobulin G Provided by Experimental and Computational Observations

The Fc portion of immunoglobulin G (IgG) is a horseshoe-shaped homodimer, which interacts with various effector proteins, including Fcγ receptors (FcγRs). These interactions are critically dependent on the pair of N-glycans packed between the two CH2 domains. Fucosylation of these N-glycans negatively affects human IgG1-FcγRIIIa interaction. The IgG1-Fc crystal structures mostly exhibit asymmetric quaternary conformations with divergent orientations of CH2 with respect to CH3. We aimed to provide dynamic views of IgG1-Fc by performing long-timescale molecular dynamics (MD) simulations, which were experimentally validated by small-angle X-ray scattering and nuclear magnetic resonance spectroscopy. Our simulation results indicated that the dynamic conformational ensembles of Fc encompass most of the previously reported crystal structures determined in both free and complex forms, although the major Fc conformers in solution exhibited almost symmetric, stouter quaternary structures, unlike the crystal structures. Furthermore, the MD simulations suggested that the N-glycans restrict the motional freedom of CH2 and endow quaternary-structure plasticity through multiple intramolecular interaction networks. Moreover, the fucosylation of these N-glycans restricts the conformational freedom of the proximal tyrosine residue of functional importance, thereby precluding its interaction with FcγRIIIa. The dynamic views of Fc will provide opportunities to control the IgG interactions for developing therapeutic antibodies.
Evaluation of dried mao pomace (antidesma bunius linn.) and lactic acid bacteria as additives to ensile stylo legume (stylosanthes guianensis ciat184)

The effect of application of dried mao pomace (DMP), fermented juice of epiphytic LAB (FJLB), and Lactobacillus paraplantarum (LPP) on the ensiling process of Stylo (Stylosanthes guianensis CIAT184) was evaluated. Stylo silage was treated with 10% DMP alone or in combination with either FJL Bor LPP. The addition of DMP to Stylo reduced the mean pH by at least 0.9 units while the use of LAB was found to maximally reduce pH by 0.21 units. Irrespective of the source of LAB, the pH reducing effect of LAB was only observed in the silages without DMP. NH3-N contents were found to be significantly affected by DMP × LAB. The use of DMP reduced the NH3-N contents by at least 50%, irrespective of the addition of LAB. Furthermore, HBut levels were below detection limits when DMP was used as a silage additive and in case the silages were not treated with DMP, the addition of either FJLB or LPP also resulted in lower HBut fractions. In view of the high NH3-N and HBut levels, it was therefore concluded that ensiling of Stylo without DMP or LAB results in an inferior silage quality. The use of DMP as a silage additive resulted in good quality silage, irrespective of the use of additional LAB.
Contrast Techniques in Light Microscopy

Thank you for downloading contrast techniques in light microscopy. As you may know, people have look numerous times for their chosen readings like this contrast techniques in light microscopy, but end up in harmful downloads. Rather than reading a good book with a cup of coffee in the afternoon, instead they juggled with some malicious virus inside their laptop. contrast techniques in light microscopy is available in our digital library an online access to it is set as public so you can download it instantly. Our book servers spans in multiple countries, allowing you to get the most less latency time to download any of our books like this one. Merely said, the contrast techniques in light microscopy is universally compatible with any devices to read.
Disruption Management for Production Rescheduling in Proportional Two-machine No-wait Flow Shop

To solve the rescheduling problem for a random or an anticipated machine disruption in proportional two-machine no-wait flow shop,a disruption management method is proposed that considering both the original objective(min.makespan) and the disruption repairing objective(min.summation of delay time). Based on the shortest processing time(SPT) rule optimal analyzing,it is proved that the right shift original schedule is optimal for the post-disruption management problem.And a predictive disruption management model is formulated based on SPT rule.By combining the ideal point-based multi-objective approaching policy with the discrete quantumbehaved particle swarm optimization and local search mechanism,a heuristic algorithm is proposed.The numerical experiments show that the model and algorithm are effective.
Comparing handline and trolling fishing methods in the recreational pelagic fishery in the Gulf of Oman

The choice of fishing gear and catching strategy should be taken into consideration in the management of fish stocks. Here, paired fishing trials in a pelagic recreational fishery compared the catch composition, catch rate and size selectivity between handline and trolling fishing methods in Iranian coastal waters of the Gulf of Oman. Total catch rate was 1.06 fish hr–1 vs 0.88 fish hr–1 for handline and trolling, respectively, a 17% difference which was significant (p < 0.05). Generally, the handline method captured more fish than trolling for most species, but size selectivity tended to be species-specific per gear type. The handline fishing method captured larger talang queenfish (Scomberoides commersonnianus), while trolling captured larger narrow-barred Spanish mackerel (Scomberomorus commerson), pickhandle barracuda (Sphyraena jello) and Indian threadfish (Alectis indicus). Technical measures, such as gear restrictions, could be applied to recreational pelagic fisheries management in the Gulf of Oman. Such measures could improve species-specific exploitation patterns.
On the Edge: Statistics & Computing

In a recent column in this series Duncan Murdoch (2000) described the benefits of writing your own scatterplot code. He mentioned the importance of specifying good scales; the flexibility ofhavingyourown software; the advantages ofoverlaying lines (or curves); the need for multiple plots; and, in an aside, the possibilities of having interactive tools for scaling and reformatting. Although that is a longish and a good list, it is in some ways more striking for what it leaves out than for what it includes, and this column discusses what else every selfrespecting scatterplot should have. Predominantly interactive features are suggested, something that is sadly missing from most statistical software. Many of the additions described would be advantageous in static displays for presentation graphics too, but it is much more effective if they are implemented interactively. Writing fully interactive software is challenging, but rewarding. The interactive tools that software should offer in general are discussed in Unwin (1999). Principles of GUI (Graphical User Interface) design relating to statistical software are outlined in Unwin et al. (1996). John Chambers has pointed
Invasive Species Population Status Modeling Using Stage Based Matrix: Mount Elgon Ecosystem

The matrix models have been applied to evaluate the impacts and management of tree species. Modeling of invasive species using stage based matrix methods has not been exploited to understand the population structure of the invasive species. The study simulated using stage-structured Lefkovitch models to assess the population structure and impacts of invasive population growth within Mount Elgon Ecosystem. The survey data were used to calculate the transition probabilities and the growth rate ( Kiptogot
Polarity text filtering based on semantic analysis

Text filtering technology based on statistics usually is ineffective when it deals with polarity text. The method overlooks the semantic restriction of text, so it isnt good for identifying polarity information. The paper provides a new text filtering method based on semantic analysis, which takes into account semantic relations in text. The experiment results indicate that the method efficiently recognizes and heads off the polarity information.