Miracle-dz/UniFAR-FTUs huggingface dataset:
Institutional Knowledge at Singapore Management University Event detection with common user interests

In this paper, we aim at detecting events of common user interests from huge volume of user-generated content. The degree of interest from common users in an event is evidenced by a signiﬁcant surge of event-related queries issued to search for documents (e.g., news articles, blog posts) relevant to the event. Taking the stream of queries from users and the stream of documents as input, our proposed framework seamlessly integrates the two streams into a single stream of query proﬁles. A query proﬁle is a set of documents matching a query at a given time. With the single stream of query proﬁles, the well-studied techniques in event detection (e.g., incremental clustering) could be easily ap-plied. In our experiments using real data collected from Blog and News search engines respectively, the proposed technique achieved very high event detection accuracy.
Myostatin knockout drives browning of white adipose tissue through activating the AMPK-PGC1 (cid:1) -Fndc5 pathway in muscle through

Myostatin (Mstn) is predominantly expressed in skeletal muscles and plays important roles in regulating muscle growth and development, as well as fat deposition. Mstn-knockout ( Mstn (cid:2) / (cid:2) ) mice exhibit increased muscle mass due to both hypertrophy and hyperplasia, and leaner body composition due to reduced fat mass. Here, we show that white adipose tissue (WAT) of Mstn (cid:2) / (cid:2) develops character-istics of brown adipose tissue (BAT) with dramatically increased expression of BAT signature genes, including Ucp1 and Pgc1 (cid:1) , and beige adipocyte markers Tmem26 and CD137 . Strikingly, the observed browning phenotype is non-cell autonomous and is instead driven by the newly deﬁned myokine irisin (Fndc5) secreted from Mstn (cid:2) / (cid:2) skeletal muscle. Within the muscle, Mstn (cid:2) / (cid:2) leads to increased expression of AMPK and its phosphorylation, which subsequently activates PGC1 (cid:1) and Fndc5. Together, our study deﬁnes a paradigm of muscle-fat crosstalk mediated by Fndc5, which is up-regulated and secreted from muscle to induce beige cell markers and the browning of WAT in Mstn (cid:2) / (cid:2) mice. These results suggest that targeting muscle Mstn and its downstream signaling represents a therapeutic approach to treat obesity and type 2 diabetes. —Shan, T. , Liang,
EMERGING STRATEGIES IN ANTI THROMBOTIC THERAPY WITH STABLE VESICULAR DISEASES – CURRENT STATE OF ART

in infarction (MI) is the most current cardio-vascular disease within the and results in heart failure once its management is improper. It has serious in mortality, morbidity, and value to It has a damaging potential for heart cells and suddenly reduces the flow rate, a clinical condition referred to as heart dysfunction that may accomplish heart condition. Myocardial infarction is outlined as sudden ischemic death of myocardial tissue. Within the clinical context, myocardial infarction is typically because of thrombotic occlusion of a coronary vessel caused by rupture of a vulnerable plaque. The adult mammalian heart has negligible regenerative capability, so the infracted cardiac muscle heals through formation of a scar. Activation of the renin-angiotensin-aldosterone system and release of growth factor-β induce conversion of fibroblasts into myofibroblasts, promoting deposition of extracellular matrix proteins. This review discusses the underlying pathophysiology, evolving views on diagnosing, risk stratification, and pharmacologic management of myocardial infarction. poor high pressure, risk factors (C-reactive protein (CRP), fibrinogen, blood vessel calcification (CAC), lipoprotein(a), large density lipoprotein (LDL)).
Are Sensitive to Unique Aspects of Language Processing: Evidence from Clitic Pronouns Word-Order.

In two self-paced reading experiments we asked whether late, highly proﬁcient, English–Spanish bilinguals are able to process language-speciﬁc morpho-syntactic information in their second language (L2). The processing of Spanish clitic pronouns’ word order was tested in two sentential constructions. Experiment 1 showed that English–Spanish bilinguals performed similarly to Spanish–English bilinguals and revealed sensitivity to word order violations for a grammatical structure unique to the L2. Experiment 2 replicated the pattern observed for native speakers in Experiment 1 with a group of monolingual Spanish speakers, demonstrating the stability of processing clitic pronouns in the native language. Taken together, the results show that late bilinguals can process aspects of grammar that are encoded in L2-speciﬁc linguistic constructions even when the structure is relatively subtle and not affected for native speakers by the presence of a second language.
Maternal low-dose vitamin A or b -carotene supplementation has no effect on fetal loss and early infant mortality: a randomized cluster trial in Nepal 1–4 Study Group

Background: The effect of vitamin A supplementation on the survival of infants aged <6 mo is unclear. Because most infant deaths occur in the first few month of life, maternal supplementation may improve infant survival. Objectives: The objective was to assess the effect of maternal vitamin A or b -carotene supplementation on fetal loss and survival of infants <6 mo of age. Design: Married women of reproductive age in 270 wards of Sarlahi district, Nepal, were eligible to participate. Wards were randomly assigned to have women receive weekly doses of 7000 m g retinol equivalents as retinyl palmitate (vitamin A), 42 mg all - trans - b -carotene, or placebo. Pregnancies were followed until miscarriage, stillbirth, maternal death, or live birth of one or more infants, who were followed through 24 wk of age. Results: A total of 43559 women were enrolled; 15832 contributed 17373 pregnancies and 15987 live born infants to the trial. The rate of fetal loss was 92.0/1000 pregnancies in the placebo group, comparable with rates in the vitamin A and b -carotene groups, which had relative risks of 1.06 (95% CI: 0.91, 1.25) and 1.03 (95% CI: 0.87, 1.19), respectively. The 24-wk mortality rate was 70.8/1000 live births in the placebo group, comparable with rates in the vitamin A and b -carotene groups, which had relative risks of 1.05 (95% CI: 0.87, 1.25) and 1.03 (95% CI: 0.86, 1.22), respectively. Conclusions: Small weekly doses of vitamin A or b -carotene given to women before conception, during pregnancy, and through 24 wk postpartum did not improve fetal or early infant survival in Nepal. Am J Clin Nutr 2000;71:1570–6.
Survives Oligocene Drowning

LAURIN, M. 1998. The importance of global parsimony and historical bias in understanding tetrapod evolution. I. Systematics, middle ear evolution and jaw suspension. Ann. Sci. Nat. 19:1–42. LAURIN, M. 2001. L’utilisation de la taxonomie phylogénétique en paléontologie: Advantages et inconvénients. Biosystema 19:197–211. LAURIN, M. 2002. Tetrapod phylogeny, amphibian origins, and the denition of the name Tetrapoda. Syst. Biol. 51:364–366. LAURIN, M. , M. GIRONDOT, AND A. DE RICQLÈS. 2000. Early tetrapod evolution. Trends Ecol. Evol. 15:118–123. LAURIN, M. , AND R. R. REISZ. 1997. A new perspective on tetrapod evolution. Pages 9–59 in Amniote origins (S. S. Sumida and K. L. M. Martin, eds.). Academic Press, New York. LEE, M. S. Y. 1996. Stability in meaning and content of taxon names: An evaluation of crown-clade denitions. Proc. R. Soc. Lond. B 263:1103–1109. LEE, M. S. Y. 1999. Stability of higher taxa in phylogenetic nomenclature—Some comments on Moore (1998). Zool. Scr. 28:361–366. LEE, M. S. Y. , AND P. S. SPENCER. 1997. Crown-clades and taxonomic stability: When is an amniote not an amniote? Pages 61–84 in Amniote origins (S. S. Sumida and K. L. M. Martin, eds.). Academic Press, New York. MCGOWAN, G. J. 2002. Albanerpetontid amphibians from the Lower Cretaceous of Spain and Italy: A description and reconsideration of their systematics. Zool. J. Linn. Soc. 135:1–32. MILNER, A. R. 1993. The Paleozoic relatives of lissamphibians. Herpetol. Monogr. 7:8–27. PADIAN, K. , J. R. HUTCHINSON, AND T. R. HOLTZ, JR. 1999. Phylogenetic denitions and nomenclature of the major taxonomic categories of the carnivorous Dinosauria (Theropoda). J. Vertebr. Paleontol. 19: 69–80.
The NH 2 -terminal peptide of (cid:2) –smooth muscle actin inhibits force generation by the myoﬁbroblast in vitro and in vivo

yoﬁbroblasts are specialized ﬁbroblasts responsible for granulation tissue contraction and the soft tissue retractions occurring during ﬁbrocontractive diseases. The marker of ﬁbroblast-myoﬁbroblast modulation is the neo expression of (cid:2) –smooth muscle actin ( (cid:2) -SMA), the actin isoform typical of vascular smooth muscle cells that has been suggested to play an important role in myoﬁbroblast force generation. Actin isoforms differ slightly in their NH 2 terminal sequences; these conserved differences suggest different functions. When the NH 2 -terminal sequence of (cid:2) -SMA Ac-EEED is delivered to cultured myoﬁbroblast in the form of a fusion peptide (FP) with a cell penetrating sequence, it inhibits their contractile activity; moreover, M upon topical administration in vivo it inhibits the contraction of rat wound granulation tissue. The NH 2 -terminal peptide of (cid:2) –skeletal actin has no effect on myoﬁbroblasts, whereas the NH 2 -terminal peptide of (cid:3) –cytoplasmic actin abolishes the immunoﬂuorescence staining for this isoform without inﬂuencing (cid:2) -SMA distribution and cell contraction. The FPs represent a new tool to better understand the speciﬁc functions of actin isoforms. Our ﬁndings support the crucial role of (cid:2) -SMA in wound contraction. The be for the understanding of the mechanisms of connective tissue remodeling; the basis for a cytoskeleton-dependent preventive and/or therapeutic strategy for ﬁbrocontractive pathological
A general revision principle method as a way between the revision principle and the rule interpolation techniques

One of the techniques for approximate reasoning is the revision principles, such as the linear revising and the semantic revising methods. These methods can not give an interpretable conclusion and can not be applied in every case: they have different strict conditions for the antecedent and the consequent sets. In order to solve this problem a general revision principle method is proposed in this paper, which can be applied to arbitrary fuzzy sets. The new method can be introduced as the extension of the former revision principle methods and a special case of the general fuzzy rule interpolation method. These two significant parts of fuzzy reasoning are discussed from one viewpoint based on the proposed method.
Numerical investigation into the blasting-induced damage 1 characteristics of rocks considering the role of in-situ stresses and 2 discontinuity persistence

9 This paper presents a 3D coupled Smoothed Particle Hydrodynamics (SPH) and Finite 10 Element Method (FEM) model, which was developed to investigate the extent of damage 11 zone and fracture patterns in rock due to blasting. The RHT material model was used to 12 simulate the blasting-induced damage in rock. The effects of discontinuity persistence and 13 high in-situ stresses on the evolution of blasting-induced damage were investigated. Results 14 of this study indicate that discontinuity persistence and spatial distribution of rock bridges 15 have a significant influence on the evolution of blasting-induced damage. Furthermore, high 16 in-situ stresses also have a significant influence on the propagation of blasting-induced 17 fractures, as well as the patterns of fracture networks. It is also shown that the blasting- 18 induced cracks are often induced along the direction of the applied high initial stresses. 19 Moreover, additional cracks are normally generated at the edges of the rock bridges probably 20 due to the relatively high stress concentration.
from studies using receiver operating characteristic curve

Internationally there is political momentum to establish networks of marine protected 12 areas for the conservation of threatened species and habitats. Practical 13 implementation of such networks requires an understanding of the distribution of 14 these species and habitats. Predictive modelling provides a method by which 15 continuous distribution maps can be produced from limited sample data. This method 16 is particularly useful in the deep sea where a number of biological communities have 17 been identified as vulnerable ‘habitats’, including Lophelia pertusa reefs. Recent 18 modelling efforts have focused on predicting the distribution of this species. However the species is widely distributed where as reef habitat is not. This study uses Maxent predictive modelling to investigate whether the distribution of the species acts as a suitable proxy for the reef habitat. Models of both species and habitat distribution 22 across Hatton Bank and George Bligh Bank are constructed using multibeam 23 bathymetry, interpreted substrate and geomorphology layers, and derived layers of 24 bathymetric position index (BPI), rugosity, slope and aspect. Species and reef presence 25 records were obtained from video observations. For both models performance is fair 26 to excellent assessed using AUC and additional threshold dependant metrics. 7.17% of 27 the study area is predicted as highly suitable for the species presence while only 0.56% 28 is suitable for reef presence, using the sensitivity ‐ specificity sum maximization 29 approach to determine the appropriate threshold. Substrate is the most important 30 variable in the both models followed by geomorphology in the RD model and fine scale 31 BPI in the SD model. The difference in the distributions of reef and species suggest that 32 mapping efforts should focus on the habitat rather than the species at fine (100m) 33 scales.
MR-InpaintNet: Toward Deep Multi-Resolution Learning for Progressive Image Inpainting

Deep learning based image inpainting methods have improved the performance greatly due to powerful representation ability of deep learning. However, current deep inpainting methods still tend to produce unreasonable structure and blurry texture, implying that image inpainting is still a challenging topic due to the ill-posed property of the task. To address these issues, we propose a novel deep multi-resolution learning-based progressive image inpainting method, termed MR-InpaintNet, which takes the damaged images of different resolutions as input and then fuses the multi-resolution features for repairing the damaged images. The idea is motivated by the fact that images of different resolutions can provide different levels of feature information. Specifically, the low-resolution image provides strong semantic information and the high-resolution image offers detailed texture information. The middle-resolution image can be used to reduce the gap between low-resolution and high-resolution images, which can further refine the inpainting result. To fuse and improve the multi-resolution features, a novel multi-resolution feature learning (MRFL) process is designed, which is consisted of a multi-resolution feature fusion (MRFF) module, an adaptive feature enhancement (AFE) module and a memory enhanced mechanism (MEM) module for information preservation. Then, the refined multi-resolution features contain both rich semantic information and detailed texture information from multiple resolutions. We further handle the refined multiresolution features by the decoder to obtain the recovered image. Extensive experiments on the Paris Street View, Places2 and CelebA-HQ datasets demonstrate that our proposed MRInpaintNet can effectively recover the textures and structures, and performs favorably against state-of-the-art methods.
Di ﬀ erentiation of the Athens Fine PM Proﬁle during Economic Recession (March of 2008 Versus March of 2013): Impact of Changes in Anthropogenic Emissions and the Associated Health E ﬀ ect

: Despite the various reduction policies that have been implemented across Europe in the past few years, Particulate Matter (PM) exceedances continue to be recorded. Therefore, with the principal aim to clarify the complex association between emissions and ﬁne particles levels, this work evaluates the impact of the anthropogenic contribution to the ﬁne PM chemical proﬁle. The ﬁeldwork was conducted during March in 2008 and 2013 and covers the periods before and during the economic recession. The experimental data were analyzed in parallel with the emissions from the Flexible Emission Inventory for Greece and the Greater Athens Area (FEI-GREGAA). The di ﬀ erentiation of the mass closure results’ and the aerosols’ character is also discussed in combination with the calculated PM 2.5 -Air Quality Indexes. The peak in the PM load and the Particulate Organic Matter (POM) component was recorded in 2013, corresponding to the enhancement of the anthropogenic input. Although the monitoring location is tra ﬃ c-impacted, the sector of heating, from both wood burning and fossil fuel, proved to be the driving force for the conﬁguration of the obtained PM picture. Especially in 2013, its contribution was two times that of tra ﬃ c. Finally, the low wind speed values led to the deterioration of the air quality, especially for the sensitive groups.
Power Efficient on DC-DC Converter Using Filter

– A n active filter-based on-chip DC–DC voltage converter for application to distributed on-chip power supplies in multi voltage systems is described in this paper. The performance of an active filter depends strongly on the Op Amp. The gain–bandwidth product of the Op Amp determines the bandwidth of the active filter. Most of the power loss takes place within the Op Amp structure, since the current provided to the output load is supplied by the Op Amp output stage. Hence, the Op Amp needs to provide tens of milliamps of current to the load devices while maintaining sufficient performance to reliably operate the active filter. This project is to evaluate a low power, in ring oscillator modification. The proposed circuit is an alternative to ring oscillator, providing a means for distributing multiple local power supplies across an integrated circuit while maintaining high current efficiency and fast response time within a small area. microprocessors, the The analytical expression for the total power consumption of a buck converter is effective in estimating the circuit efficiency characteristics. The buck converter efficiency as determined by simulation at the target design point is 86%, which only differs by 2.4% from the efficiency determined from the analytic expression. Selc¸uk K¨ose and Eby G. Friedman proposed an area efficient fully monolithic hybrid voltage regulator. A hybrid voltage regulator module for an on-chip DC-DC voltage converter is proposed in this paper. The circuit is appropriate for point-of-load voltage regulation due to an ultra area efficient architecture. The proposed voltage regulator is a hybrid combination of a switching DC-DC voltage converter and a low-dropout regulator exploiting active circuitry rather than bulky passive devices within the filter structure. One method is to use decoupling capacitors to reduce the impedance of the power distribution network over a wide frequency range. Since the active devices switch at high frequencies, the decoupling capacitors require sufficient time to recharge before the next switching event. The efficacy of the decoupling capacitors depends upon the distance from the decoupling capacitor to the power supply. Both off-chip and on-chip DC-DC voltage converters are generally used to supply power to modern ICs. Conventional DC-DC converters can be grouped into three categories.
A comparative study on treatment of wastewaters with various biodegradability and various pH values using single‐chamber microbial fuel cells

This work assessed the performance of a single‐chamber microbial fuel cell (MFC) with various substrates. Primary settled domestic wastewaters were used to simulate wastewaters of high biodegradability; while phenol‐based wastewaters and benzene‐based wastewaters were used to simulate wastewaters of low biodegradability. Experiments were performed at initial pH values of 6, 7 and 8. The maximum voltage production, power density and removal of substrate were obtained using primary settled domestic wastewater, whereas the lowest values were obtained using phenol‐based wastewater. The maximum chemical oxygen demand removal efficiency, phenol removal efficiency and benzene removal efficiency were 80.8, 63.3 and 77.8%, respectively. The performance of the MFC was enhanced by increasing the influent pH. The lowest coulombic efficiencies were obtained from phenol‐based wastewater and benzene‐based wastewater, which indicated that electrogenic bacteria were not the primary microorganisms responsible for the biodegradation of low biodegradable wastewater.
Inﬂuence of the Active Screen Plasma Power during Afterglow Nitrocarburizing on the Surface Modiﬁcation of AISI 316L

: Active screen plasma nitrocarburizing (ASPNC) increases the surface hardness and lifetime of austenitic stainless steel without deteriorating its corrosion resistance. Using an active screen made of carbon opens up new technological possibilities that have not been exploited to date. In this study, the e ﬀ ect of screen power variation without bias application on resulting concentrations of process gas species and surface modiﬁcation of AISI 316L steel was studied. The concentrations of gas species (e.g., HCN, NH 3 , CH 4 , C 2 H 2 ) were measured as functions of the active screen power and the feed gas composition at constant temperature using in situ infrared laser absorption spectroscopy. At constant precursor gas composition, the decrease in active screen power led to a decrease in both the concentrations of the detected molecules and the di ﬀ usion depths of nitrogen and carbon. Depending on the gas mixture, a threshold of the active screen power was found above which no changes in the expanded austenite layer thickness were measured. The use of a heating independent of the screen power o ﬀ ers an additional parameter for optimizing the ASPNC process in addition to changes in the feed gas composition and the bias power. In this way, an advanced process control can be established.
Impact of a lifestyle intervention among subjects with the metabolic syndrome in a primary health care setting: evidence from a regression discontinuity design

background The metabolic syndrome (MetS) is a well-known entity related to cardiovascular disease and type 2 diabetes. Many subjects with MetS are affected by central obesity. Randomized clinical trials have demonstrated that lifestyle changes exert beneficial effects on obesity and other MetS-components. However these trials have been performed under highly controlled conditions and the generalizability across persons, settings and outcomes may be limited. The purpose of this study was to evaluate the feasibility and the effect of the implementation of a lifestyle intervention (inclusive of possible blood pressure treatment) in subjects with the MetS in a primary health care setting. The effect was assessed using a regression discontinuity design. two blood pressure in subjects with the MetS after one year to our results larger in obesity and blood pressure were observed. the beneficial effect be overestimated the assignment to the treatment groups was not randomized. Two in of intervention with to obtained in these differences in methods and intensity of applied. Trials in clinical outpatient clinics university centers, were self-referred, more obese and weight loss obtained longer more to implement in daily practice. daily randomized trials