Miracle-dz/UniFAR-FTUs huggingface dataset:
Peripheral tissue oximetry

Estimation of regional tissue oxygenation (rStO 2 ) by near infrared spectroscopy enables non-invasive end-organ oxygen balance monitoring and could be a valuable tool in intensive care. However, the diverse absolute values and dynamics of different devices, and overall poor repeatability of measurements are a problem. The aim of the present study is to test the hypothesis that INVOS 5100C, FORE-SIGHT and NONIN EQUANOX 7600 have similar properties concerning absolute values, repeatability, and sensitivity to changes in rStO 2 . To test repeatability the sensors were repositioned 20 times during hemodynamic steady state on the adult forearm. After-wards six vascular occlusions by inﬂation of an upper arm cuff were done to achieve low oxygenation in the forearm. Absolute values were compared by repeated-measures ANOVA, repeatability was estimated by the within-subject standard deviation, S w , and response to changing oxygenation by the down slope of rStO 2 during vascular occlusion in the respective arm. 10 healthy adults, 21–29 years old, with double skinfolds on the forearm less than 10 mm participated. The median rStO 2 was 70.7 % (interquartile range (IQR) 7.7 %), 68.4 % (IQR 8.4 %), and 64.6 % (IQR 4.8) with INVOS, NONIN, and FORE-SIGHT, respectively, the median rate of decline was 13.2 %/min (IQR 9.6), 22.8 %/min (IQR 18.0), and 10.8 %/min (IQR 6.0), and the same-site repeatability was 2.9 % (95 % CI 2.4–3.3), 4.6 % (CI 3.9–5.3), and 2.0 % (CI 1.7–2.3). INVOS gave signiﬁcantly higher steady state values than FORE-SIGHT, and NONIN had the steepest decline in rStO 2 , but the poorest repeatability. Two measures of signal-to-noise were similar among devices. This suggests that good repeatability comes at the expense of low sensitivity to changes in oxygenation. Values of rStO 2 on the forearm from INVOS, NONIN and FORE-SIGTH cannot be used interchangeably.
Institutional Knowledge at Singapore Management University Institutional Knowledge at Singapore Management University Revisiting the Multicultural Experience-creativity Link: The Effects Revisiting the Multicultural Experience-creativity Link: The Effects of Cultural Distance and Comparison Mindset 

A growing literature provides evidence for the multicultural experience–creativity link such that exposure to the juxtaposition of two cultures facilitates individual creativity. The underlying mechanisms for this relationship, however, are still far from being well explored. Drawing upon the novel perspective of motivated cognition, we hypothesize that two factors interact to affect creative outcomes: (a) perceived cultural distance between the two juxtaposed cultures, and (b) comparison mind-sets. Specifically, we argue that individuals’ creative performance will be increased only when a difference mind-set is employed to process the cultural stimuli that are sufficiently different from each other. In two studies, individuals exposed to dual cultural primes with higher levels of perceived cultural distance consistently performed more adeptly in creative insight tasks when they personally predisposed to or experimentally manipulated to adopt a difference (vs. similarity) mind-set. Theoretical and practical implications are discussed.
Wavenumber selection for small-wavelength Goertler vortices in curved channel flows

The problem of wavenumber selection for fully nonlinear, small-wavelength Goertler vortices in a curved channel flow is considered. These types of Goertler vortices were first considered by Hall & Lakin (1988) for an external boundary layer flow. They proved particularly amenable to asymptotic description, it was possible to consider vortices large enough so that the mean flow correction driven by them is as large as the basic state, and this prompted the authors to consider them in a curved channel flow as an initial application of the phase-equation approach to Goertler vortices. This involves the assumption that the phase variable of these Goertler vortices varies on slow spanwise and time scales, then an analysis of both inside and outside the core region, to which vortex activity is restricted, leads to a system of partial differential equations which can be solved numerically for the wavenumber. The authors consider in particular the effect on the wavenumber of the outer channel wall varying on the same slow spanwise scale as the phase variable.
Insulin-like growth factor binding protein 1 predicts cardiovascular morbidity and mortality in patients with acute myocardial infarction and type 2 diabetes

Objective: There are indications that the IGF system is related to both type 2 diabetes (T2DM) and cardiovascular (CV) disease. We tested the hypothesis that low IGF-I and high IGF binding protein-1 (IGFBP-1) predict future cardiovascular mortality and morbidity in patients with acute myocardial infarction (AMI) and T2DM. Research design and methods: The DIGAMI 2 trial recruited 1253 patients with T2DM and AMI of which 575, the present material, were enrolled in a biochemical program with repeated blood sampling. Primary and secondary endpoints were adjudicated CV mortality and a composite of CV events (CV death, reinfarction or stroke). Multiple Cox proportional hazard regression was used to study the relationship between endpoints and the variables. Admission variables were used for the survival analysis and for blood glucose and HbA1c updated mean values during follow-up were also available. Results: During a median follow-up period of 2.2 years, 131 (23%) patients died from all-cause and 102 (18%) from CV disease while 175 patients (30%) suffered from at least one CV event. The independent predictors for CV death in the Cox regression model were (HR, 95% CI): ln updated mean blood glucose (12.2 (5.8 - 25.7), age (+5 years; 1.5, 1.4-1.7), ln IGFBP-1 (1.4, 1.1-1.8) and ln S-Creatinine at admission (2.4, 1.3-4.2). The model predicting CV events contained the same variables (ln IGFBP-1 at admission; 1.2, 1.0-1.4). Conclusions: High levels of IGFBP-1 at admission are associated with increased risk for CV mortality and morbidity in T2DM patients with AMI.
The impact of obesity on skeletal muscle architecture in untrained young 1 versus old women 2

Background: It is unknown if loading of the lower limbs through additional storage 44 of fat mass as evident in obesity would promote muscular adaptations similar to 45 those seen with resistance exercise. It is also unclear whether ageing would modulate any such adjustments. Objective: This study aimed to examine the relationships between adiposity, 49 ageing and skeletal muscle size and architecture. Method: 100 untrained healthy women were categorised by age into young (Y) 52 (mean ± SD: 26.7 ± 9.4 yrs) versus old (O) (65.1 ± 7.2 yrs) and BMI classification 53 (underweight, normal weight, overweight and obese). Participants were assessed 54 for body fat using duel energy x-ray absorptiometry, and for gastrocnemius 55 medialis (GM) muscle architecture (skeletal muscle fascicle pennation angle and 56 length) and size (GM muscle volume and physiological cross sectional area 57 (PCSA)) using B-mode ultrasonography. Results: GM fascicle pennation angle (FPA) in the obese Y females was 25 per 60 cent greater than underweight (p=0.001) and 25 per cent greater than normal 61 weight (p=0.001) individuals, whilst O females had 32 per cent and 22 per cent 62 greater FPA than their underweight (p=0.008) and normal weight (p=0.003) 63 counterparts. Furthermore, FPA correlated with body mass in both Y and O 64 females (Y r=0.303; p<0.001; O r=0.223; p=0.001), yet no age-related differences 65 in the slope or r-values were observed (P>0.05). Both GM muscle volume 66 (p=0.003) and PCSA (p=0.004) exhibited significant age × BMI interactions. In 67 addition, muscle volume and PCSA correlated with BMI, body mass and fat mass. Interestingly, ageing reduced both the degree of association in these correlations 69 (p<0.05) and the slope of the regressions (p<0.05). Conclusion: Our findings partly support our hypotheses in that obesity-associated 72 changes in GM PCSA and volume differed between the young and old. The 73 younger GM muscle adapted to the loading induced by high levels of body mass, 74 adiposity and BMI by increasing its volume and increasing its pennation angle, ultimately enabling it to produce higher maximum torque. Such an adaptation to increased loading did not occur in the older GM muscle. Nonetheless, the older GM muscle increases in FPA to an extent similar to that seen in young GM muscle, an effect which partly explains the relatively enhanced absolute maximum torque observed in obese older females.
Significant enhancement in the electrical conductance properties of ethylene propylene diene monomer using the nanoâ•’SiO<sub>2</sub> particles

Shanxi Key Laboratory of Mining Electrical Equipment and Intelligent Control, College of Electrical and Power Engineering, Taiyuan University of Technology, Taiyuan, China Electrical and Computer Engineering, University of Connecticut, Storrs, Connecticut, USA State Grid Jincheng Power Supply Company, Jincheng, China Shanxi Jincheng Anthracite Mining Group Co., Ltd, Jincheng, China School of Electrical Engineering, Shandong University, Jinan, China
Human DDX3X Unwinds Japanese Encephalitis and Zika Viral 5 (cid:48) Terminal Regions

: Flavivirus genus includes many deadly viruses such as the Japanese encephalitis virus (JEV) and Zika virus (ZIKV). The 5 (cid:48) terminal regions (TR) of ﬂaviviruses interact with human proteins and such interactions are critical for viral replication. One of the human proteins identiﬁed to interact with the 5 (cid:48) TR of JEV is the DEAD-box helicase, DDX3X. In this study, we in vitro transcribed the 5 (cid:48) TR of JEV and demonstrated its direct interaction with recombinant DDX3X (K d of 1.66 ± 0.21 µ M) using microscale thermophoresis (MST). Due to the proposed structural similarities of 5 (cid:48) and 3 (cid:48) TRs of ﬂaviviruses, we investigated if the ZIKV 5 (cid:48) TR could also interact with human DDX3X. Our MST studies suggested that DDX3X recognizes ZIKV 5 (cid:48) TR with a K d of 7.05 ± 0.75 µ M. Next, we performed helicase assays that suggested that the binding of DDX3X leads to the unwinding of JEV and ZIKV 5 (cid:48) TRs. Overall, our data indicate, for the ﬁrst time, that DDX3X can directly bind and unwind in vitro transcribed ﬂaviviral TRs. In summary, our work indicates that DDX3X could be further explored as a therapeutic target to inhibit Flaviviral replication
in Competitive Markets.

This paper characterizes the optimal information structure in competitive insurance markets with adverse selection. We consider a regulator that assigns ratings to individuals according to their expected costs. Insurers observe these ratings and compete as in Akerlof (1970). The optimal rating system minimizes ex-ante risk subject to participation constraints. We prove that in any such market there exists a unique optimal system under which all individuals trade and the ratings match low-cost types with high-cost types negative assortatively. We provide a simple algorithm that yields the optimal system and examine implications for government regulations of insurance markets.
G Observation of spheroidal normal mode multiplets below 1 mHz using ensemble empirical mode decomposition

Superconducting gravimeter (SG) records after the 2004 Sumatra M w 9.0, 2010 Maule M w 8.8 and 2011 Tohoku M w 9.1 earthquakes are selected to observe the singlets of six spheroidal normal mode multiplets below 1 mHz ( 0 S 2 , 2 S 1 , 0 S 3 , 0 S 4 , 1 S 2 and 3 S 1 ). To clearly observe their spectral splitting, the ensemble empirical mode decomposition (EEMD) is applied to SG records as a dyadic ﬁlter bank. Comparisons of the product spectra obtained from the direct residual gravity records and those obtained after using EEMD clearly conﬁrm the validity of EEMD. After using EEMD, all of the singlets of the six multiplets, particularly those of 0 S 4 and 1 S 2 , are completely observed with high signal-to-noise ratio, whereas some of singlets could not be well resolved without the application of EEMD. This study demonstrates that EEMD may be important in the detection of the splitting of some weak and low-frequency seismic modes. The relevant observation results may improve the Earth’s density models.
AIS Electronic Library (AISeL) Positive Personal Development through eSports

This research-in-progress paper investigates the personal development players experience from eSports participation by identifying the benefits that players gain from play, and why these are important to players. This study utilises a qualitative methodology consisting of semi-structured laddering interviews, and content analysis to analyse data. 12 high level groups, split into 8 benefits and 4 values, were identified of importance to players, with the attainment of these benefits allowing eSports players to achieve their values. The initial identification of benefits and values contribute towards IS literature by understanding how benefits can drive player participation in eSports, and how benefits are tied to players’ values. The results of this study can also be leveraged to promote eSports to external audiences to improve its legitimacy and perception. they gain from eSports . This study uses qualitative data consisting of semi-structured laddering interviews with eSports players, and content analysis to analyse collected data. The following provides information regarding the data collection and interview procedure before discussing the data analysis process.
Development of ultrasound diagnostic test for preoperative airway evaluation

Objective: The objective of this research is to investigate the validity and applicability of ultrasonography as a diagnostic test for difficulties in intubation through direct laryngoscopy and/or ventilation under facial mask, comparing it with the traditional clinical method of screening. Method: A double blind accuracy study was performed at Ophir Loyola Hospital, Belém-PA, Brazil. Patients of both genders, between 18 and 80 years of age, with body mass index between 18 and 40 kg/m 2 , submitted to general anesthesia were included. Traditional clinical inspection, ultrasound scanning of the airways and after anesthetic induction were performed, easy or difficult ventilation as well as difficulty during direct laryngoscopy based on Cormack-Lehane classification were observed. For inspection related to ventilation and intubation, the traditional clinical measurements established in the literature were used. For sonographic inspection, we analyzed the distances: chin-hyoid, skin-hyoid, skin-epiglottis midpoint, skin-thyroid cartilage, skin-anterior commissure of the vocal cords and skin distance-cricoid cartilage. The data were analyzed by the T-student and Mann-Whitney tests, and their validity was verified by the ROC curve. Results: As for the prediction of direct laryngoscopy, the ultrasonography obtained greater validity as a diagnostic test, surpassing the clinical method. Presenting sensitivity of 71.4%, specificity of 60.3% and high negative predictive value of 92.1%, better predicting the real cases of difficult intubations by the proposed cervical distance measurements. When evaluated in isolation, mask ventilation did not present statistical relevance by ultrasonography. A formula to estimate the difficulty during laryngoscopy based on ultrasound measurements was listed and will serve as a basis for the creation of software for the development of new technologies to assist in diagnostic screening. Conclusion: It was concluded that ultrasonography is a valid and superior diagnostic test to the clinician to anticipate difficulties with direct laryngoscopy, being an effective test at the bedside.
Toward Evolvable Document Management for Study Programs Based on Modular Aggregation Patterns

—Despite technological and operational business advances over the past decades, organizations are still required to draft and manage documents. Although a lot of these documents have taken an electronic form, their structure is in essence still the same as their analogue and physical predecessors. In this paper, we present a different view of documents as we imagine them as modular structures. Based on the patterns of the artifacts they describe, documents can be modularized and decomposed into ﬁne-grained text modules. This leads to easier maintenance of the text modules as they offer a clear aggregate structure and any information is stored in only one text module. This enables re-usability and allows for a greater versatility of the information stored in the text modules. One can generate several new types of documents with different purposes as to the ones imaginable at this moment. All of this enables the creation of truly evolvable documents according to the Normalized Systems theory.
Analysis on Video Retrieval Using Speech and Text for Content-Based Information

: E-Teaching has become more and more popular in the last previous years. The amount of showing video data on the World Wide Web (WWW) is growing rapidly. Therefore, a more useful method for video retrieval in WWW or within large teaching video archives is urgently needed. This paper presents an analysis and approaches followed for automated video indexing and video search in enormous teaching video archives. First of all, we apply automatic video segmentation and key-frame detection to offer a visual guideline for the video content navigation. Parallel, we extract textual metadata by applying video Optical Character Recognition (OCR) technology on key-frames and Automatic Speech Recognition (ASR) on teaching audio tracks. The OCR and ASR transcript as well as detected slide text line types are adopted for keyword extraction, by which both video-and segment-level key words are extracted for content-based video browsing and search. The ideas are captured with behavioural parameters of proposed indexing functionalities are analysed.
Toward a New Method of Decoding Algebraic Codes Using Groebner Bases

Abstract : A binary BCH error control code is a vector subspace of binary N- tuples. Algebraically, the code is generated by a polynomial having binary coefficients and roots in GF(2m). It is decoded by computing a set of syndrome equations which are multivariate polynomials over GF(2m) and which exhibit a certain symmetry. If the number of transmission errors in a received word does not exceed a bound t for the code, the roots of the syndromes are the locations, in the received word, of those errors. These multivariate polynomials are taken as the basis for an ideal in the ring of polynomials in t variables over GF(2m). A celebrated algorithm by Buchberger produces a reduced Groebner basis of that ideal. It tums out that, since the common roots of all the polynomials in the ideal are a set of isolated points, this reduced Groebner basis is in triangular form, and the univariate polynomial in that basis is the well known BCH error locator polynomial, the roots of which specify the error locations. Decoding is algorithmically complete when this polynomial is known. Decoding, Algebraic functions, Polynomials
AI Assisted Video Workﬂow: Exploring UIs for Human-AI Collaboration

Video production and distribution have become very affordable and accessible. A large body of research is available in machine learning for audio, visual and language processing and more recently generation of multimedia content. Machine learning provides promising materials for designing innovative video production workﬂows. However, there is a lack of studies and expertise around how would video editors receive and use machine learning in their work. As a part of ongoing university and industry joint innovation project, this project aims to explore the the challenges of integrating machine learning into video editing workﬂows. Through setting up and running experiments with AI embedded prototypes on video production workﬂow, we aim to explore the design space of using AI in video editing interfaces and potential of human-in-the-loop machine learning in creative designs.
Dynamic of linker histone in cellular differentiation.

Linker histones are essential components of chromatin, but the distributions and functions of many during cellular differentiation are not well understood. Here, we show that H1.5 binds to genic and intergenic regions, forming blocks of enrichment, in differentiated human cells from all three embryonic germ layers but not in embryonic stem cells. In differentiated cells, H1.5, but not H1.3, binds preferentially to genes that encode membrane and membrane-related proteins. Strikingly, 37% of H1.5 target genes belong to gene family clusters, groups of homologous genes that are located in proximity to each other on chromosomes. H1.5 binding is associated with gene repression and is required for SIRT1 binding, H3K9me2 enrichment, and chromatin compaction. Depletion of H1.5 results in loss of SIRT1 and H3K9me2, increased chromatin accessibility, deregulation of gene expression, and decreased cell growth. Our data reveal for the first time a specific and novel function for linker histone subtype H1.5 in maintenance of condensed chromatin at defined gene families in differentiated human cells.
International in Computer Science and Software Engineering SG-DSDV: Elegant and Goal Based DSDV for Routing in Mobile Ad hoc Networks

— A mobile ad hoc network is a continuously self-configuring, infrastructure-less network of mobile devices connected without wires. As nodes are mobile in this network, routing is an important challenge. In this paper, we proposed new intelligent algorithm (SG-DSDV) for routing to improve DSDV routing protocol. In proposed algorithm, scores are considered for nodes according to energy of nodes, congestion in the routing queue of nodes and link states. Algorithm uses scores for selecting best rout and chooses rout with highest score as main route and rest of discovered routs are stored in temporal memory or cache of nodes to use them if main route is damaged or interrupted. SG-DSDV is implemented in NS2 simulator and results show proposed algorithm improves the delay of sent packets, routing overhead and delivered packets of DSDV protocol.