Miracle-dz/UniFAR-FTUs huggingface dataset:
Investigation into clinicopathological and pathological findings, prognosis, and aetiology of lorikeet paralysis syndrome in rainbow lorikeets (Trichoglossus haematodus )

Objective To report the temporal and spatial distribution of rainbow lorikeets presenting with lorikeet paralysis syndrome (LPS) and their clinicopathologic and pathologic findings, exposure to toxins, and response to treatment. Methods Records of lorikeets admitted in 2017 and 2018 to facilities in south‐east Queensland (QLD) were reviewed and LPS and non‐LPS cases were mapped and their distribution compared. Plasma biochemistries and complete blood counts were done on 20 representative lorikeets from south‐east QLD and Grafton, New South Wales (NSW). Tissues from 28 lorikeets were examined histologically. Samples were tested for pesticides (n = 19), toxic elements (n = 23), botulism (n = 15) and alcohol (n = 5). Results LPS occurred in warmer months. Affected lorikeets were found across south‐east QLD. Hotspots were identified in Brisbane and the Sunshine Coast. Lorikeets had a heterophilic leucocytosis, elevated muscle enzymes, uric acid and sodium and chloride. Specific lesions were not found. Exposure to cadmium was common in LPS and non‐LPS lorikeets. Treated lorikeets had a 60–93% See Table 2 depending on severity of signs. Clinical significance The primary differential diagnosis for lorikeets presenting with lower motor neuron signs during spring, summer and autumn in northern NSW and south‐east Queensland should be LPS. With supportive care, prognosis is fair to good.
Enteric Pathogens and Reactive Arthritis: Systematic Review and Meta-Analyses of Pathogen-Associated Reactive Arthritis.

The objective of this systematic review and meta-analysis was to estimate the proportion of postinfectious reactive arthritis (ReA) after bacterial enteric infection from one of four selected pathogens. We collected studies from PubMed, Web of Science, and Embase, which assessed the proportion of postinfectious ReA published from January 1, 2000 to April 1, 2018. Papers were screened independently by title, abstract, and full text; papers in English, Spanish, and Portuguese utilizing a case-control (CC) or cohort study design, with a laboratory confirmed or probable acute bacterial enteric infection and subsequent ReA, were included. The proportion of ReA cases was pooled between and across pathogens. Factors that can induce study heterogeneity were explored using univariate meta-regression, including region, sample size, study design, and ReA case ascertainment. Twenty-four articles were included in the final review. The estimated percentage of cases across studies describing Campylobacter-associated ReA (n = 11) was 1.71 (95% confidence interval [CI] 0.49-5.84%); Salmonella (n = 17) was 3.9 (95% CI 1.6-9.1%); Shigella (n = 6) was 1.0 (95% CI 0.2-4.9%); and Yersinia (n = 7) was 3.4 (95% CI 0.8-13.7%). Combining all four pathogens, the estimated percentage of cases that developed ReA was 2.6 (95% CI 1.5-4.7%). Due to high heterogeneity reflected by high I2 values, results should be interpreted with caution. However, the pooled proportion developing ReA from studies with sample sizes (N) <1000 were higher compared with N > 1000 (6% vs. 0.3%), retrospective cohort studies were lower (1.1%) compared with CC or prospective cohorts (6.8% and 5.9%, respectively), and those where ReA cases are identified through medical record review were lower (0.3%) than those identified by a specialist (3.9%) or self-report (12%). The estimated percentage of people who developed ReA after infection with Campylobacter, Salmonella, Shigella, or Yersinia is relatively low (2.6). In the United States, this estimate would result in 84,480 new cases of ReA annually.
Synergic fabrication of pembrolizumab loaded doxorubicin incorporating microbubbles delivery for ultrasound contrast agents mediated anti-proliferation and apoptosis

Abstract This study evaluated pembrolizumab-conjugated, doxorubicin (DOX)-loaded microbubbles (PDMs) in combination with ultrasound (US) as molecular imaging agents for early diagnosis of B cell lymphomas, and as a targeted drug delivery system. Pembrolizumab, a monoclonal CD20 antibody, was attached to the surfaces of DOX-loaded microbubbles. PDM binding to B cell lymphoma cells was assessed using immunofluorescence. The cytotoxic effects of PDMs in combination with ultrasound (PDMs + US) were evaluated in vitro in CD20+ and CD20– cell lines, and its antitumor activities were assessed in Raji (CD20+) and Jurkat (CD20–) lymphoma cell-grafted mice. PDMs specifically bound to CD20+ cells in vitro and in vivo. Contrast enhancement was monitored in vivo via US. PDM peak intensities and contrast enhancement durations were higher in Raji than in Jurkat cell-grafted mice (p < 0.05). PDMs + US treatment resulted in improved antitumor effects and reduced systemic toxicity in Raji cell-grafted mice compared with other treatments (p < .05). Our results showed that PDMs + US enhanced tumor targeting, reduced systemic toxicity, and inhibited CD20+ B cell lymphoma growth in vivo. Targeted PDMs could be employed as US molecular imaging agents for early diagnosis, and are an effective targeted drug delivery system in combination with US for CD20+ B cell malignancy treatment.
Deep Learning Approach for Text Summarization

1Student, Information Technology Department, MITCollege of Engineering, Pune, Maharashtra, India, 2Student, Information Technology Department, MITCollege of Engineering, Pune, Maharashtra, India, 3Student, Information Technology Department, MITCollege of Engineering, Pune, Maharashtra, India, 4Student, Information Technology Department, MITCollege of Engineering, Pune, Maharashtra, India, 5Assistant Professor, Information Technology Department, MITCollege of Engineering, Pune, Maharashtra, India ---------------------------------------------------------------------***---------------------------------------------------------------------Abstract Text summarization refers to the technique of cropping long pieces of text. Neural network models have been provided a new feasible approach for abstractive text summarization. Abstractive means generating new sentences from the original text which might not be present in the original text. These neural network models have two defects: They are likely to reproduce factual details inaccurately and they tend to repeat themselves. In this work we propose a novel design that augments the standard sequence-tosequence attentional model in two orthogonal ways. Primarily, we employed a pointer-generator network that selects words from the given text by pointing, which helps accurate replication of data, keeping the ability to introduce new words by the means of the generator. Secondly, we use a coverage mechanism to keep track of what has been summarized, which discontinues repetition. We apply our model to CNN/Daily mail dataset to perform training the model. Accuracy of the generated summary is checked by ROUGE points. The system provides additional features such as downloading the generated summary in PDF file as well as text-to-speech conversion.
Influence of jack bean (Canavalia ensiformis (L) DC) milk processing on bioactive compounds and its antioxidant activity

Jack bean (Canavalia ensiformis (L) DC), a kind of legume consumed in some countries, but has rarely processed into food products. Given that the beans contained proteins at 20-30% (dry basis) (Ade-Omowaye et al., 2015; Doss et al., 2011), the beans have a potency to be processed into a plant-based milk product. Moreover, several studies have shown flavonoids contained in this bean (Olugboyega & Edem, 2018). Therefore, there are various health benefits, including antioxidants and anti-diabetes that have been reported (Ade-Omowaye et al., 2015; Vadivel et al., 2012; Sowndhararajan et al., 2011). To date, the milk processing from the beans as well as the phenolics occurrence in the bean milk have not been investigated yet.
Constructing an Artworld Influencer Network by Mining Social Media

Abstract The author demonstrates a methodology for constructing a network map of the artworld. She uses tweets posted by a manually composed set of exemplar artworld actors and Natural Language Processing (NLP) methods to identify significant artworld actors, including those without Twitter accounts. Identified artworld actors form communities detected using the Louvain method, and their authority is evaluated with the HITS centrality method. The resulting artworld network exhibits the ability to proceed from a small original set of exemplar actors to identify new artworld actors and provides a wealth of data that would be difficult to collect otherwise.
Lower Extremities’ Kinematic Sequence and Kinetics during first Pull in Classic Snatch

The primary purpose of this study was to identify and compare the lower extremities’ kinematic joints initiation sequence during the first pull phase of the classic snatch among male and female elite weightlifting athletes. As the secondary purpose, the maximal angle extension of joints, sub-phase duration, joint angular displacement and velocity, barbell velocity and the ground reaction force produced during the classic snatch sub-phases were determined and compared between genders. Six men (age: 19.9±2.29 years, height: 1.67±0.04 m, and body mass: 87.96±2.68 kg) and six women (age: 19.72±1.35 years, height: 1.55±0.42 m, and body mass: 70.25±10.78 kg) were tested for 85% of their 1 repetition classical snatch movement. Kinematics were captured at 100 Hz using a Qualisys motion capture system with eight cameras, and markers were placed bilaterally on the hips, knees and ankle joints. Kinetics were captured using the Kistler fixed force plate. The results revealed that a significant difference between males and females in term of hip joint initiation sequence, ground reaction force and barbell velocity. The hip angle among the female athletes initiates the start movement earlier than among male athletes. The ground reaction force and barbell velocity are higher in males compared to females. These findings suggest that the female weightlifters are not in a position to produce higher degrees of extension, thus reducing their efficiency in lifting and ability to take more substantial resistance. Having a limited angle extension results in the involved muscles not being fully contracted.
Estimation of the lattice energy and the free energy of formation of the series M 4 P 2 O 7 ( M = Li , Na , K , Rb and Cs )

Lattice energies and Gibbs energies of formation are determined for a series of alkaline diphosphate (pyrophosphate) of formula M4P2O7(s) where M = Li, Na, K, Rb and Cs. The lattice energy, UPOT, is calculated according to two schema of decomposition using the standard Born-Haber-Fajans (BHF) thermochemical cycle and Glasser equation. The results led to the standard molar enthalpy of formation of potassium diphosphate (K4P2O7) as equals -3212 kJ mol. This value differs only by 0.6% from literature data. Free Gibbs energy of formation of these compounds was estimated by the determination of their absolute entropy according to Jenkins and Glasser procedure.
Treatment of plywood from burning by synthesis a new protective coating through sol-gel

Approximately 750,000 multi-family housing units experienced roofing problems due to fire-retardant-treated (FRT) plywood sheathing failure since 1985 until 1995. The problem is caused by excessive exposure to solar radiation. Plywood is not safe because it contains glue that may be toxic, harmful to life and human skin when exposed to ignition. The aims of this research built on modifying plywood to be fire resistant. Thus, the sol gel technique was applied to prepare a new fire-retardant coating containing different volumes of H3PO4 (0, 0.3, 0.7, and 1.1 ml) to protect the plywood from ignition. The flammability properties of the different coated samples evaluated by the following measurements using standard methods: limiting oxygen index (LOI), ignitability and thermogravimetric analysis (TGA). The results indicated that, the highest flame retardant LOI obtained at H3PO4 1.1ml reaching ≈ 150% relative to the un-treated; these results are supported through ignitability and thermogravimetric analysis. © 2013 Elixir All rights reserved ARTICLE INF O
Modification of the Wilshire strain equation: an application to RR1000

Being able to predict creep strain as a function of time is important both in preventing aeroengine blades from rubbing against their outer casings, but also in being able to convert small punch test data into equivalent uniaxial test results using numerical models. The capability of the Wilshire equation to interpolate creep curves was assessed using uniaxial creep tests carried out on RR1000. In this paper, an artificial neural network was used to modify the Wilshire equation for times taken to reach various strains, so that the parameters of the Wilshire equation could be interpolated as a function of strain. The model was then evaluated using statistics on predictive accuracy, which showed that the model was capable of predicting the shape and scale of the creep curves with high accuracy. These modifications also revealed that the activation energy is dependent upon the average internal stress and thus strain.
Designing and Delivering Webinars to Improve Science Communication and Engagement between Environmental Researchers and Natural Resource Practitioners

Abstract Research across natural resource management disciplines has identified an implementation gap between researchers and managers, where institutional norms and practices limit integration of novel data and observations into decision-making. This gap has largely been addressed using one-way science communication tools such as publications and conference presentations. While these tools can be designed and delivered effectively, mounting evidence suggests two-way communication builds more trust, enhances engagement, and may lead to more active use of scientific information in decision-making. The National Oceanic and Atmospheric Administration (NOAA) Western Regional Collaboration Team’s West Watch webinar is a one-way communication tool that shares information about climate, weather, and ocean condition anomalies to an internal audience of NOAA experts and key partners. NOAA is interested in expanding this tool to improve information accessibility and use by communities of interest that NOAA serves. This research uses a mixed-methods approach to evaluate how West Watch could change to function as a two-way communication tool, facilitating bilateral information movement between research presenters and the audience. Research results, supported by literature, inform five best practices and recommendations for changes to West Watch, as well as the design and implementation of future science communication tools.
Nano-scratch and nano-indentation study of diamond-like carbon/NiP-SiC nanocomposite bilayer

To overcome the poor adhesion of diamond-like carbon (DLC) films to the steel substrate, an interlayer can be used. In this study, the effect of the addition of NiP-SiC nanocomposite coating as an interlayer in comparison to the NiP coating has been investigated on tribological properties of the DLC layer. Using nano-scratch and nano-indentation tests, the mechanical and nanotribological behaviour of the DLC layers, such as scratch resistance, coefficient of friction, interfacial adhesion between DLC layer and substrate, and hardness were characterised. DLC/NiP-SiC samples showed higher adhesion, hardness, elastic modulus, and lower friction coefficient. These results reveal the improved tribological properties of DLC film by applying the NiP-SiC nanocomposite interlayer in comparison to using the pure NiP interlayer.
Ironmen competitors exhibit unique gait patterns

Human gait patterns have been shown to be stable over prolonged periods (Horst et al., 2017) and unique to individuals (Lin et al., 2011). Commonly, such insights were derived from data collected within a controlled laboratory environment and a heterogeneous study population (i.e. males and females; Horst et al., 2019). It remains unclear if comparable insights can be derived from a more homogenous study population (i.e. elite male athletes) and from data collected within a natural environment (i.e. outdoors). Especially, since the running styles of elite athletes may be more similar as they have evolved to be most economic (Folland et al., 2017) and may reside within a narrower solution space.
Analysis of video review during official judo matches: effects on referee’s decision and match results

ABSTRACT This study aimed to describe the frequency of video review (VR) used during international judo matches. The duration and time of VR occurrence and the effect of VR on subsequent referee’s decisions and match outcomes were investigated. Video recordings from the matches in which the VR was used in the 2020 Grand Slams (n = 122) were analysed. The main results showed most VR occurrences were from 1 to 2 min for female athletes (p = 0.03). Lightweight categories in both male and female groups showed the highest frequency of VR (37.3%). No significant differences were detected for VR duration and time when VR occurred considering sex and weight categories (p = 0.91, p = 0.26, respectively). A significant association was found between the type of action and the referee’s decision (p < 0.01), being score assignment the most frequent action (77.6% of male and 64.8% of female). More than 80% of the athletes (82.3% male and 78.3% female) won their matches after referees’ checking. We concluded that VR is often used at the beginning of the match mainly in the female group, mostly concerning scoring attribution, which directly affected the match result in more than 80% of the cases.
The importance of having a conceptual stage when reporting non-randomized studies

Formal guidelines for statistical reporting of non-randomized studies are important for journals that publish results of such studies. Although it is gratifying to see some journals providing guidelines for statistical reporting, we feel that the current guidelines that we have seen are not entirely adequate when the study is used to draw causal conclusions. We therefore offer some comments on ways to improve these studies. In particular, we discuss and illustrate what we regard as the need for an essential initial stage of any such statistical analysis, the conceptual stage, which formally describes the embedding of a non-randomized study within a hypothetical randomized experiment.
Dynamic mechanical analysis as a predictor for slip resistance and traction in footwear

Adequate friction between footwear and surface is essential to reduce the risk of slipping (Chang et al., 2001) and maximise athletic performance (Luo & Stefanyshyn, 2011). Footwear outsole materials are constructed of viscoelastic elastomers (e.g. rubber or thermoplastic polyurethane (TPU)). The mechanical properties of outsoles are frequently measured with simple tools, e.g. durometer for hardness and profilometer for surface roughness (Iraqi et al., 2020). However, viscoelastic elastomers have complicated material characteristics, and are highly dependent of temperature and load frequency. These material characteristics have previously been investigated with dynamic mechanical analyses (DMA) in relation to friction between rubber and surface in tire-road friction scenarios (Lorenz et al., 2015). The outcome measures are G0 (energy loss in internal motion), G0 (elastic response), and tan(d) (G00/G0). Tan(d) is a measure of the material’s ability to lose energy by internal friction. However, DMA as a tool for optimising footwear traction has received very little or no attention in footwear science. It is believed that the friction properties of outsoles are affected by sliding speed, which may change the elastic response and loss factor.
Case fatality risk estimated from routinely collected disease surveillance data: application to COVID–19

Case fatality risk (CFR) is the probability of death among cases of a disease. A crude CFR estimate is the ratio of the number deaths to the number of cases of the disease. This estimate is biased, however, particularly during outbreaks of emerging infectious diseases such as COVID-19, because the death time of recent cases is subject to right censoring. Instead, we propose deconvolution methods applied to routinely collected surveillance data of unlinked case and death counts over time. We begin by considering the death series to be the convolution of the case series and the fatality distribution, which is the subdistribution of the time between diagnosis and death. We then use deconvolution methods to estimate this fatality distribution. This provides a CFR estimate together with information about the distribution of time to death. Importantly, this information is extracted without the need to make strong assumptions used in previous analyses. The methods are applied to COVID-19 surveillance data from a range of countries illustrating substantial CFR differences. Simulations show that crude approaches lead to underestimation, particularly early in an outbreak, and that the proposed approach can rectify this bias. An R package called covidSurv is available for implementing the analyses.
Synthesis and in vitro antimicrobial, antioxidant, and antiproliferative activities of some new pyrano[2,3-c]pyrazoles containing 1,2-azaphospholes, 1,3,2-diazaphosphinines and phosphonate moieties

Abstract New 1,2-azaphosphole, 1,3,2-diazaphosphinine, and phosphonate derivatives containing pyrano[2,3-c]pyrazole moiety were achieved. The synthetic pathways depended on the reaction of 6-amino-3-methyl-1,4-diphenyl-1,4-dihydropyrano[2,3-c]pyrazole-5-carbonitrile with some phosphorus reagents such as diethyl phosphite, phosphorus sulfides, and phenyl phosphorus halides under different conditions. Compounds 6 and 7 recorded potent antibacterial and antifungal activities with lower toxicity, while compounds 4 and 6 displayed promising antioxidative properties. Further, compounds 4 and 9 exhibited potent cytotoxic effects against MCF-7, HepG-2, and HCT-116 cancer cells. The early apoptotic cell death was observed by the compounds in all types of the treated cells. Compounds 3, 5, 7, 10, and 14 recorded low to moderate percentages of necrosis and late apoptosis toward all treated cells. Graphical Abstract
A first step to defining a measurement method for footwear comfort in children

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Household Wealth and Child Body Mass Index: Patterns and Mechanisms

Wealth plays a unique role in shaping later-life health risk, but the relationship between wealth and child health remains largely unexplored. Using longitudinal data from the Panel Study of Income Dynamics (PSID) (1994–2013), this study uses multilevel mixed-effects models and the parametric g-formula approach to both assess the relationship between household wealth and child body mass index (BMI) and identify the mechanisms linking wealth to child BMI. We find that household wealth is negatively associated with childhood BMI. In addition to finding a strong, direct association, we also find that household wealth indirectly patterns child BMI and obesity risk through household spending and family stress processes. These findings provide new insights into the links between wealth, child health, and early-life population health disparities.