Miracle-dz/UniFAR-FTUs huggingface dataset:
Data migration ecosystem for big data invited paper

Data Migration is the process of moving data from a system or systems to a new environment. Often, it is a sub-activity of a business application deployment. Big data is defined as data that is huge, has heterogeneous data dictionaries and involves complex manipulation. Due to nature of the process complexity and its resources hungry approach in migrating Big Data, special attention is required to have a proven methodology and ecosystem to govern the process. The Data Migration Ecosystem for Big Data is the productive set of interacting processes, practices and environments, to collect data from one location, storage medium, or hardware/software system, to cleanse, transform and transfer it to another. The processes and practices are governed by rules and disciplines, with the goal of ensuring information is complete, of high accuracy and consistent. This paper is based on our experience in migrating data for a Malaysia government agency, which involves approximately 1 billion rows of data from 31 heterogeneous sources / systems. Some of the data migrated was created in the seventies (1970), for which the business logic has since been enhanced or changed. The challenge is further complicated by available data being from proprietary databases that are non-RDMS compliance and includes data that is manually maintained in Microsoft Excel spreadsheets.
A quantitative study of daytime sleepiness induced by carbamazepine and add‐on vigabatrin in epileptic patients

Introduction – The clinical relevance of daytime sleepiness associated with carbamazepine (CBZ) and vigabatrin (VGB) was objectively assessed by the multiple sleep latency test (MSLT) and nocturnal sleep recordings. Material and methods – Twenty‐six patients with partial epilepsy and mean monthly seizure frequency of 4, aged 18 to 48 years, receiving chronic monotherapy with CBZ and subsequent VGB addition for 2 months (14 patients), were compared with a group of healthy subjects. Subjective daytime sleepiness was complained by 13 patients on CBZ monotherapy and 9 patients during VGB add‐on treatment. Results – No differences in nocturnal sleep parameters, but significantly shorter daytime sleep latencies at the MSLT, were detected in CBZ‐treated patients as compared with healthy controls. Addition of VGB therapy did not further enhance objective daytime sleepiness. Conclusion – Some sleepiness occurs in chronically CBZ‐treated epileptic patients, which can be objectively measured by the MSLT, but it is not aggravated by add‐on VGB.
Improved control of a chaotic reaction system using modified delay co-ordinate feedback

Delay co-ordinate feedback (DCF) control may be used to attain periodic oscillations in systems exhibiting low dimensional chaos when measurements of only a single variable are available. This can be achieved by reconstructing the chaotic attractor using time delayed measurements of the variable. In this paper, a modification to the DCF algorithm (2D-DCF) that takes into account sampling rate limitations is introduced. Through application to a chaotic chemical reactor model, it is shown that this algorithm can outperform the conventional DCF controller when measurement sampling frequencies are decreased.
Rac1 Function Is Required for Src-induced Transformation

The proto-oncogene c-Src has been implicated in the development and progression of a number of human cancers including those of colon and breast. Accumulating evidence indicates that activated alleles of Src may induce cell transformation through Ras-ERK-dependent and -independent pathways. Here we show that Rac1 activity is strongly elevated in Src-transformed cells and that this small G protein is a critical component of the pathway connecting oncogenic Src with cell transformation. We further show that Vav2 and the ubiquitously expressed Rac1 guanine nucleotide exchange factor Tiam1 are phosphorylated in tyrosine residues in cells transfected with active and oncogenic Src. Moreover, phosphorylation of Tiam1 in cells treated with pervanadate, a potent inhibitor of tyrosine phosphatases, was partially inhibited by the Src inhibitor SU6656. Using truncated mutants of Tiam1, we demonstrate that multiple sites can be tyrosine-phosphorylated by Src. Furthermore, Tiam1 cooperated with Src to induce activation of Rac1 in vivo and the formation of membrane ruffles. Similarly, activation of JNK and the c-jun promoter by Src were also potently increased by Tiam1. Together, these results suggest that Vav2 and Tiam1 may act as downstream effectors of Src, thereby regulating Rac1-dependent pathways that participate in Src-induced cell transformation.
Deconvolution using natural image priors-Lecture notes

If the matrixCf is a full rank matrix, and no noise is involved in the imaging process, the simplest approach to deconvolve y is to invert Cf and definex = C −1 f y. Or in the frequency domain, X(ν,ω) = Y(ν,ω)/F(ν,ω) This, however, is very rarely stable enough. For example, the inverse is not defined in frequencies (ν,ω) for which F(ν,ω) = 0. Even in case|F(ν,ω)| is not exactly 0 but small, the inverse is very sensitive to noise. That is, if the Y we are observing includes some noise Y(ν,ω) = F(ν,ω)X(ν,ω) + n, than the inverse will produceY(ν,ω)/F(ν,ω) = X(ν,ω)+n/F(ν,ω), so, when|F(ν,ω)| is small the noise contribution is increased.
Shoulder arthrodesis in adult brachial plexus injury: what is the optimal position?

Brachial plexus injuries are a major indication for shoulder arthrodesis. However, there is no consensus concerning the optimal position of the glenohumeral joint for fusion. Between 1997 and 2008, 19 shoulder arthrodeses were performed using pelvic reconstruction plates. The radiographic and functional characteristics of 13 patients of mean age 46 years were examined at a mean of 101 months after arthrodesis. Arthrodeses showed 30° mean angle of abduction, 32° forward flexion and 44° internal rotation of the humerus with respect to the scapula. Abduction >35° and forward flexion ≥30°seem to offer slightly better functional results. Internal rotation ≤45° significantly relates to better ability of the hand to reach the face (p = 0.012). Neither abduction >35° nor forward flexion ≥30° showed a higher prevalence of periscapular pain. Abduction around 35° and forward flexion around 30° are needed for good functional results. Internal rotation should not exceed 45°.
Early Understanding of Subject and Object Wh-Questions

In this study, we used the splitscreen preferential looking paradigm to test 13-, 15-, and 20-month-olds' developing understanding of simple matrix what-questions of the forms "What hit the X? " (subject-question) and "What did the X hit? " (object-question). Infants responded appropriately to subject-questions by 15 months of age, and to both subject- and object-questions by 20 months. At no age did infants look longer toward the object overtly mentioned in the question, as might be expected based on a surface account of early language acquisition. This suggests that infants may have some understanding of these complex structures long before they are produced.
Motivation and Demotivation of a Four-Valued Logic

Belnap offers two arguments for the usefulness of four-valued logic. I argue that one of them, which rests on interpreting valuations as states of our information, when taken seriously collapses into an argument for two-valued logic in which relevance is lost, and that the other, resting on Scott's thesis, is not an argument for its usefulness
Pancreatic enzyme supplementation improves the incretin hormone response and attenuates postprandial glycemia in adolescents with cystic fibrosis: a randomized crossover trial.

CONTEXT Cystic fibrosis-related diabetes is characterized by postprandial, rather than fasting, hyperglycemia. Gastric emptying and the release of the incretin hormones [glucagon-like peptide-1 (GLP-1) and glucose dependent insulinotropic polypeptide (GIP)] are central to postprandial glycemic control. Lipolysis is required for fat to slow gastric emptying and stimulate incretin release. OBJECTIVE We aimed to determine the effect of pancreatic enzyme replacement therapy (PERT) on postprandial glycemia in adolescents with cystic fibrosis (CF). DESIGN This was a double-blinded randomized crossover trial. Subjects consumed a high-fat pancake, with either PERT (50 000 IU lipase) or placebo. Gastric emptying was measured by a breath test and blood sampled frequently for plasma blood glucose, insulin, glucagon, GLP-1, and GIP. Data were also compared with seven healthy subjects. PARTICIPANTS Fourteen adolescents (13.1 ± 2.7 y) with pancreatic-insufficient CF and seven healthy age-matched controls participated in the study. MAIN OUTCOME MEASURE Postprandial hyperglycemia was measured as peak glucose and area under the curve for blood glucose at 240 minutes. RESULTS CF subjects had postprandial hyperglycemia compared with controls (area under the curve, P < .0001). PERT reduced postprandial hyperglycemia (P = .0002), slowed gastric emptying (P = .003), and normalized GLP-1 and GIP secretion (P < .001 for each) when compared with placebo, without affecting insulin. CONCLUSION In young people with pancreatic insufficient CF, PERT markedly attenuates postprandial hyperglycemia by slowing gastric emptying and augmenting incretin hormone secretion.
Disproportional Control and Insider Entrenchment: Evidence from Capital Structure Choices and Institutional Investment

A dual-class ownership structure, accompanied by disproportional control rights, is traditionally considered to be an inferior form of governance. We examine how the capital structure choices made by dual-class firms (i.e., by their controlling shareholders or insiders), as well as the investment choices made by the non-controlling institutional investors in these firms, vary with the presence of dual-class ownership and the degree of disproportional control it entails. We consider two sources of disproportional control: the difference between voting rights and cash flow rights and the difference between board election rights and cash flow rights. We find that dual-class firms, as well as firms with higher levels of disproportional control, have higher levels of leverage, a greater likelihood of issuing private debt, a higher fraction of long-term debt, and greater reliance on financial covenants. We also find that dual-class firms have significantly higher levels of institutional ownership, including ownership by institutions that are activist types, face stricter prudence laws, and have longer horizons. Overall, our evidence is not consistent with dual-class ownership promoting rent-seeking behavior. On the contrary, our evidence supports the view that insiders choose other mechanisms, debt in particular, to commit to not expropriate non-controlling shareholders.
Anti-β2 Glycoprotein I Antibodies and Platelet Activation in Patients with Antiphospholipid Antibodies: Association with Increased Excretion of Platelet-Derived Thromboxane Urinary Metabolites

Summary Platelet activation may contribute to the increased risk of thrombotic complications in patients with antiphospholipid antibodies (aPL). The increased urinary excretion of 11-dehydro-thromboxane B2 (11-DH-TXB2) reported in patients with lupus anticoagulant (LA) and/or anticardiolipin antibodies (aCL) reflects in vivo platelet activation. However the majority of autoimmune aPL are directed to β2 glycoprotein I (β2GPI) or prothrombin (II). We investigated the relationship of these antibodies with 11-DH-TXB2 urinary excretion in 34 patients with aPL. The urinary 11-DH-TXB2 was measured by EIA after extraction on octadecyl columns and purification on silica gel columns, which was validated by thin-layer chromatography/EIA procedure. A significantly increased excretion of 11-DH-TXB2 was found in aPL patients as compared to 18 normal controls (p <0.01). But no differences were seen in the excretion of 11-DH-TXB2 between patients with or without LA, or aCL. The number of patients with anti-II antibodies was too small to draw any conclusion. In contrast, patients with anti-β2GPI antibodies IgG at moderate/high titre (group A, n = 14) had higher levels of urinary 11-DH-TXB2 than those at low titre or negative (group B, n = 20) (p = 0.01). The group A of patients presented an increase in 11-DH-TXB2 compared to controls (p <0.001), but no statistically significant difference was found between patients from the group B and normal controls. A correlation between levels of urinary 11-DH-TXB2 and titre of antibodies was only found for anti-β2GPI-IgG (rs = 0.51, p <0.005). Our data show that the observed platelet activation in aPL patients is related to the presence of antibodies reacting with β2GPI.
Preparation of the mammalian organ of Corti for scanning electron microscopy *

The effect of various standard tissue preparation procedures for scanning microscopy on the morphology of the mammalian organ of Corti has been examined. Comparison was made of (i) different fixatives: glutaraldehyde (GA) alone, osmium (Os) alone, GA and Os together and GA followed by Os; (ii) freeze‐drying (FD) versus critical point‐drying (CPD); (iii) ligand binding of osmium with thiocarbohydrazide (TOTO procedure) versus sputter coating to provide a conductive coat. Results were assessed in terms of known structural parameters in fresh tissue. It is shown: (i) that double fixation, either GA, Os together or GA followed by Os, consistently produced less tissue distortion than either fixative alone, (ii) that FD produced less shrinkage of the tissue than CPD, and (iii) that the TOTO procedure appeared to rigidify the tissue and enhanced preservation of the morphology.
Intestinal Epithelial Cell Up-Regulation of LY6 Molecules during Colitis Results in Enhanced Chemokine Secretion

In the healthy colon, intestinal epithelial cells (IEC) form a physical barrier separating the myriad of gut Ags from the cells of the immune system. Simultaneously, IEC use several mechanisms to actively maintain immunologic tolerance to nonpathogenic Ags, including commensal bacteria. However, during inflammatory bowel disease (IBD), the line of defense provided by IEC is breached, resulting in uncontrolled immune responses. As IEC are a principal mediator of immune responses in the gut, we were interested in discerning the gene expression pattern of IEC during development and progression of IBD. Laser capture microdissection and microarray analysis were combined to identify the LY6 superfamily as strongly up-regulated genes in inflamed IEC of the colon in two models of murine colitis. Surface expression of LY6A and LY6C on IEC is induced by several cytokines present within the colitic gut, including IL-22 and IFN-γ. Furthermore, cross-linking of LY6C results in production of a number of chemokines which are known to be involved in the immunopathogenesis of IBD. Increased chemokine production was cholesterol dependent, suggesting a role for lipid raft structures in the mechanism. As such, LY6 molecules represent novel targets to down-regulate chemokine expression in the colon and limit subsequent inflammation associated with IBD.
Screening and Characterization of Rhizospheric Chitinolytic Bacteria for Evaluation of Their Potential as Biocontrol Agent against Phytopathogenic Fungi

Plant diseases cause considerable losses in crop production and storage. Now-a-days growers still rely heavily on chemical pesticides to prevent or control these diseases, which can result in environmental contamination. The presence of pesticide residues on food also cause social and economic problem that heavily affects the economy of the country. Fungi (Fusarium sp., Rhizoctonia sp., Alternaria sp., Pythium sp. etc.) are parasitic pathogens which attack crop plants and are very dangerous. Fungal phytopathogens cause serious problems worldwide causing diseases like rusts, smuts, rots and wilt; which damages the crop (Goma et al., 2011). Biological control, using microorganisms to suppress plant disease offers powerful and alternative tool against the use of synthetic chemicals.
Anorexia Nervosa in a Developing Country

chronic schizophrenia (the Type 2 syndrome of Crow, or classical Kraepelinian schizophrenia) may be due to cerebral dopaminergic underactivity. Crow, however, thinks that the Type 2 syndrome is more likely to be due to â€œ¿ cell loss and structural changes in the brainâ€•. Whatever the cause of chronic Kraepelinian schizo phrenia, both authors supported the concept of a â€ ̃¿ dopaminehypothesis' to explain the positive symp toms of acute Schneiderian schizophrenia. I believe that such a view of the role of cerebral dopamine in psychiatric illness is too restricted. The â€ ̃¿ dopaminehypothesis' of schizophrenia obviously was a simplistic notion from its birth. The discovery that the neuroleptic drugs used to control acute positive Schneiderian symptoms of schizo phrenia all possessed the ability to antagonize cerebral dopamine receptor action led to the concept that over-activity of cerebral dopamine mechanisms might cause schizophrenia. As both Mackay and Crow pointed out, these drugs only control the positive symptoms such as florid delusions, hallucinations and thought disorder of schizophrenia. However, neuro leptic drugsalsocontrol similar symptomsoccurring in many other types of illness. Neuroleptic drugs frequently are used to control mania. Casualty officers, general physicians, psychiatrists and neuro logists have for many years employed neuroleptic drugs to calm patients with acute toxic confusional states (delirium) due to drugs, fever, metabolic encephalopathy, encephalitis, stroke, brain tumour, and so on. Indeed, neurologists sometimes are forced to employ neuroleptics to control the acute toxic confusional state provoked by levodopa in patients with Parkinson's disease. Levodopa also may provoke florid delusions and visual hallucinations in the setting of clear consciousness and preserved insight in some patients with Parkinson's disease, and such symptoms also respond to the administration of a neuroleptic drug. The other plank of the â€ ̃¿ dopamine hypothesis' was the discovery that amphetamine could provoke a syndrome akin to schizophrenia in some individuals, but amphetamines also can cause a typical acute toxic confusional state. Such clinical observations suggest that the current focus of attention on dopamine in schizophrenia is too narrow a view. I suggest that the â€ ̃¿ dopamine hypothesis' for schizophrenia should originally have been constructed in a wider context as a â€ ̃¿ dopamine hypothesis' to explain the positive symptoms of acute psychotic illness, whatever its cause. C. D. MARSDEN Department of Neurology, Institute of Psychiatry and King's College Hospital Medical School, London SE5 References MACKAY, A. V. P. (1980) Positive and negative schizo phrenic symptoms and the role of dopamine. British JournalofPsychiatry, 137, 379â€”86. CROW, T. J. (1980) Positive and negative schizophrenic symptoms and the role of dopamine. British Journal of Psychiatry, 137, 383â€”6.
Contributions of “Mathematics for Elementary Teachers” Courses to Teaching: Prospective Teachers’ Views and Examples

A Mathematics course for elementary school teachers (MFET) is required in North America in most teacher education programs. Our study investigates the perceptions of prospective elementary school teachers with respect to the contributions of such a course to their teaching. The results show that acquiring an understanding of concepts from the elementary school curriculum is the main contribution that they perceive. We conclude with two perspectives – a pessimistic one and an optimistic one – on this finding.
Reliable Microjoints Formed by Solid–Liquid Interdiffusion (SLID) Bonding Within a Chip-Stacking Architecture

In this research, thousands of 20-μm pitch microbumps with a diameter of 10 μm and a structure of a pure Sn cap on a Cu pillar were electroplated on 8-inch wafers, and those wafers were then respectively singularized as a top chip and bottom Si interposer for stacking. Two methods, namely conventional reflow and solid-liquid interdiffusion (SLID) bonding, were adopted to interconnect the microbumps. In the former case, the as-plated Sn caps were fluxed, and the chip was then placed on the Si interposer. Afterward, the Sn caps on the chip and on the Si interposer were melted and interconnected at a peak temperature of 250 °C. The flux residues were cleaned after reflow, and the microgap between the chip and the Si interposer was fully sealed by a capillary underfill. In the SLID bonding process, the oxides on the as-plated Sn caps were removed by a plasma etcher first, and then the chip was placed on the interposer with a bonder as well, subsequently, the Sn caps were heated to 260°C to react with the Cu pillar to form Cu6Sn5. In the final step, the intermetallic microjoints were protected by the same capillary underfill. After assembly, the Joint Electron Devices Engineering Council preconditioning test was used to screen the test vehicles for reliability assessment, and then a temperature cycling test was performed to predict the lifespan of the microjoints. The test results showed that the microjoints formed by SLID bonding provided a superior reliability performance to those assembled by reflow. The fracture of the microjoints was caused by the volume contraction induced by the growth of Cu6Sn5, but the failure mechanisms of those two microjoints were quite different.
On-Chip GIPD Bandpass Filter Using Synthesized Stepped Impedance Resonators

By utilizing synthesized stepped impedance resonators (SIRs) with high/low-impedance synthesized coplanar waveguides, a novel on-chip three-pole bandpass filter is realized on glass integrated passive device process. The synthesized SIR, formed by quasi-lumped series inductors and MIM capacitors, provides an effective way to utilize the chip area efficiently. The footprint of the miniaturized filter, 0.045 ×0.029 λg2, is less than one-third the size of the second smallest one in the literature. The upper stopband, extending from 1.4 f0 to 3.77f0, is also the widest among the reported on-chip SIR filter designs. The |S21| at f0 (4.2 GHz) is -3.2 dB, while the bandwidth is 29%.
Dual-Band Circularly Polarized Antenna with Differential Feeding

A dual-band circularly polarized antenna is presented in this paper. A rectangular patch antenna with gap-feeding structure is firstly designed, and 3-dB axial-ratio bandwidth from 2.35 to 2.48GHz is obtained. A parasitic square ring is placed on the rear of the rectangular patch as a band-notch unit operating around 2.4 GHz. Then an original wide circularly polarized band is split into two bands from 2.25 to 2.31 GHz and from 2.46 to 2.53GHz. By adopting differential feeding, symmetrical patterns are achieved. Measurement results show that two 3-dB axial-ratio bands of 2.6% (2.25–2.31GHz) and 2.0% (2.51–2.56GHz) are obtained with a small frequency ratio of 1.11.