Miracle-dz/UniFAR-FTUs huggingface dataset:
Evaluation of Frontal Teeth Stabilization after Root Apex Resection among the Ukrainian Young People

Objective: To develop a protocol of improved stabilization of teeth after root apex resection among young people using endodonto-endoossal implants and assessing its effectiveness. Material and Methods: Thirty-six patients were previously selected and divided into Group 1 (without additional stabilization) and Group 2 (with additional stabilization). The efficacy of treatment in both clinical groups was estimated at 90, 180 and 360 days, respectively. The results were evaluated on the Miller scale in the Flesrar modification. Density of bone tissue was expressed in Hounsfield units. Results: The average mobility indices over 90 days indicate a significant lower mobility of teeth in patients in Group 2, where as an advanced method, the RTR with an additional filling of the bone marrow defect with an osteoplastic material was chosen as the method of treatment (+ 18.0 ± 0.21 U.M. 10.0 ± 0.8 μm, p<0.05). In Group 1, 90 and 180 days after surgery, the density of bone tissue in the defect area was 756.3 ± 2.45 HU and 880.1 ± 4.34 HU. In Group 2, these indices were insignificantly higher and amounted to 834.3 ± 4.35 HU and 880.4 ± 2.56 HU. After 360 days after treatment in the first clinical group the bone density index was 957.4 ± 2.45 HU, while in the second group - 1003.3 ± 4.38 HU. Conclusion: The mobility of teeth among patients on 90-th day corresponded to level 1, and on 360-th day corresponded to level 0, indicating the effectiveness of the proposed method. The biomechanical stabilization of the teeth was confirmed by the results of densitometry among patients of both groups, in particular, the recovery of bone density in the affected site was observed after 360 days.
The Evaluation of Clinical Pathway Implementation on Cerebral Infarction in the Inpatient Care Unit of Bantul X Hospital

Stroke remains one of the major health problems, not only in Indonesia but also in the world. The improvement of stroke service process is expected to support better outcomes of stroke service quality. One of the clinical management uses is the implementation of clinical pathway (CP). The purpose of this study was to explore the implementation of clinical pathway cerebral infarction in the inpatient unit of Bantul X hospital. A convergent parallel mix-method design with case study approach. The quantitative sample is the patient’s total cerebral infarction medical record (June 2016-November 2016, n=27) and ICPAT checklist. Qualitative samples are doctors, nurses and people involved in the implementation of CP cerebral infarction obtained from deep interview with purposive sampling technique. The result of this study, ICPAT dimensio 1 (CP format) content and quality are good. Dimension 2 (CP documentation) moderate content and good quality. Dimension 3 (CP development) moderate content and good quality. Dimension 4 (CP implementation) content and quality are poor. Dimension 5 (CP maintenance) content and quality are moderate. Dimension 6 (role of organization) content and quality are good. Compliance rate of completeness of CP form is 22% and compliance of filling clinical pathway is 0 %. Most contraints due to busyness of the officer and time constraints. To improve the cerebral infarction CP implementation need more socialization, training, regular evaluation and full time facilitator.
A Spatial Epidemiological Analysis of Human and Bovine Cryptosporidiosis in Southern Ontario, from 2011 to 2014

A SPATIAL EPIDEMIOLOGICAL ANALYSIS OF HUMAN AND BOVINE CRYPTOSPORIDIOSIS IN SOUTHERN ONTARIO, from 2011 to 2014 Andrea Nwosu University of Guelph, 2018 Advisor: Professor O. Berke Cryptosporidium is a parasitic zoonotic pathogen that can result in human and animal morbidity and mortality and has been detected in Southern Ontario— an area densely populated by humans and cattle. This thesis is a study of the spatial distribution of human and bovine cryptosporidiosis across 29 Public Health Unit areas in Southern Ontario from 2011 to 2014. The overall raw farm-level prevalence of bovine cryptosporidiosis was 45% [95% CI: 42%-48%]. The raw cumulative incidence risk of human cryptosporidiosis was 6.91 [95%CI: 6.47-7.39] cases per 100,000 population. Overlapping disease clusters of both human and bovine cryptosporidiosis were identified in the Central West region of Southern Ontario. A Spatial Poisson regression showed that the incidence risk ratio of cryptosporidiosis in humans increases with increasing dairy cattle density. These findings suggest that dairy cattle play a role in the distribution of human cryptosporidiosis. Further studies on the transmission of cryptosporidiosis in Southern Ontario and the specific role of dairy cattle are warranted.
Child Maltreatment in the Zhejiang Province of China: The Role of Parental Aggressive Tendency and a History of Maltreatment in Childhood

This study aimed to explore the role of parental aggression and parental childhood maltreatment experience in the maltreatment of children in Zhejiang Province, eastern China. The study sites were two urban and two rural schools. Children aged ten to 16 years and their parents completed separate questionnaires, which included: parental childhood maltreatment; parental aggressive tendency; and maltreatment of children. Questionnaires were completed by 611 parents and 821 children. Fifty‐eight per cent of parents reported maltreatment of their children. Higher parental aggression scores were associated with an increased risk for all types of child maltreatment (relative risk ratios (RRRs) or odds ratios (ORs) ranged from 1.06–1.07 for each point higher on the aggression scale). Parental childhood maltreatment was significantly associated with an increased risk of moderate/severe physical maltreatment of children (OR = 1.80 (1.08, 3.00)); parental aggression was an explanatory factor for this association. Parental childhood maltreatment was positively associated with emotional maltreatment of children (OR = 1.89 (1.27, 2.83)). This was partly explained by parental aggression. In conclusion, high levels of child maltreatment were admitted by parents in China, suggesting the need for parenting education. Parents with a higher aggressive tendency were more likely to maltreat children. Parental aggressive tendency was an explanatory factor for the intergenerational transmission of maltreatment, indicating the possibility of identifying parents' aggressive tendencies for early prevention.
The Effect of High-Frequency Repetitive Transcranial Magnetic Stimulation on Functional Indices of Affected Upper Limb in Patients with Subacute Stroke

Background: Repetitive transcranial magnetic stimulation (rTMS) is a novel technique that may improve recovery in patients with stoke, but the role of rTMS as an applied and practical treatment modality for stroke rehabilitation has not been established yet. Objective: This study was conducted to determine the effects of a rehabilitation program (RP) in conjunction with rTMS on functional indices of the paretic upper limb in the subacute phase of stroke. Material and Methods: In this experimental study, twenty patients in the subacute phase of stroke were randomly assigned into two groups: The high frequency rTMS (HF-rTMS) in conjunction with RP (experimental group), and the RP group (control group). The experimental group received 10 sessions of 20 Hz rTMS on the affected primary motor cortex and the other group received 10 sessions of RP. In experimental group, RP for the paretic hand was conducted following rTMS session. Box and block test (BBT), Fugl-Meyer Motor Assessment for upper limb (FMA-UL), grip strength and pinch strength were used to assess motor function before the first session and after the last session of treatment. Results: Significant improvement in BBT, FMA-UL, grip strength and pinch strength was observed in both groups. Improvement of BBT and grip strength was significantly greater in the experimental group rather than the control group (p<0.05). FMA-UL score and the pinch strength were greater in the experimental group, although the differences were not statistically significant. Conclusion: HF-rTMS in conjunction with RP is effective to improve the function of upper limb. It seems HF-rTMS is a novel feasible and safe technique for hemiparesis patients in the subacute phase of stroke.
Fractal box-counting technique for shelf life study of grapes by laser speckle image processing

Background: In agriculture, it is essential to follow the ripening of fruits and vegetables which is a subject of interest economically. The use of optical non-destructive method is the most suitable technique for evaluating the ripening stage of fruits when they ripen off-tree and eventually to predict the optimum storage life. Many methods are recently developed in optical image processing. The texture correlation function and the fractal box counting (FBC) of biospeckle pattern have been described. Materials and Methods: The dynamic speckle patterns known as boiling speckle are produced by a coherent light illumination incident on the active material of biological tissue. A high coherent laser source He-Ne with 632 nm with neutral density filter and charge-coupled device camera are the major components of the experimental setup. The same experiment may be done by a green laser of wavelength 541 nm (green color). The same procedure continues to take the speckle images in periodically. Results and Discussion: With the help of FBC method in image processing technique, we can assess optically rough surface fruits such as grapes in this work. According to the FBC theory, the speckle images (R1) give a binary counting value D = 1.7640 at the initial stage. Gray image converted into binary image which gives the fractal counting value D = 1.7554 at later on phase. It means that the specimen (grapes) becomes dry periodically and its value is affected by the surrounding environmental condition. Conclusion: Using the dynamic speckle phenomenon or biospeckle method, we demonstrated the assessment of shelf life activity of grapes. The visual phase of the autocorrelation function gives reliable results showing the variation in activity because of the internal changes caused by decreasing water content and then becomes dry grape stage. The correlation function of speckle patternand the Fractal Box Counting (FBC) technique has been proposed as a tool to estimate the postharvest stage of grapes. The bioactivities of fruits and vegetable materials are based on Brownian motion, due to subcellular organs. This indicates the senescence or biological aging characteristics. The quantification of the biospeckle phenomena is associated with the moment of inertia, time history of speckle pattern and grey level co-occurrence matrix. We proposed a new FBC technique to assess the shelf life of grapes.
Nutrition in Central America and Panama: Comparative Data and Interpretations

Most public health and nutrition experts now accept that the undernutrition that affects children in developing nations results from a combination of complex social and biological factors. These factors may lead to low availability of adequate foods to meet energy and nutrient requirements and/or to poor use of foods consumed because of the overwhelming toll of infections to which most children and other family members are exposed in poor areas of developing countries [1] Adequate amounts of food may be obtained from items available in a community and/or through purchasing power (depending on income and prices). If sufficient demand exists in a community, markets are likely to be able to offer enough commodities through local production and/or imports. Thus, the low availability of foods to families in rural areas of developing nations is generally related to lack of purchasing power rather than to insufficient supply. A comprehensive government strategy to tackle food and nutrition problems should include health and environmental sanitation programmes geared to improving the use of consumed foods. These programmes can include primary health care activities, introduction of potable water, hygienic disposal of excrete and garbage, control of domestic animals, and adequate housing. All of these may substantially reduce the frequency and severity of prevailing infections. Therefore health programmes, by themselves, are likely to produce important improvements in child survival and better growth patterns [2], indicating improved nutritional status. The prevailing low levels of income in rural areas of Central America result from the low cash-generating capacity of labourers (lack of employment and/or low wages) and the insufficient production of foods by subsistence farmers. Such situations preclude these persons from fulfilling their own and their families’ energy and nutrient needs. Some of the strategies available to and exercised by governments of developing nations to improve the purchasing power of undernourished persons include generating labour opportunities for deprived areas, providing subsidized low-price shops, periodically revising and improving minimum wages, and providing supplementary feeding and other types of food distribution.
Fibrinolysis-treated myocardial infarction in a patient with missed spontaneous coronary artery dissection associated with takotsubo syndrome: case report

Abstract Background Spontaneous coronary artery dissection (SCAD) is an under-recognized acute cardiac disease entity. It is often missed, or misdiagnosed as coronary spasm, coronary atherosclerotic lesion, or thrombotic coronary occlusion. During the last years, SCAD also has been reported to be ‘misdiagnosed as takotsubo syndrome (TS)’ in patients with features consistent with both conditions. Spontaneous coronary artery dissection may present as an acute coronary syndrome and sometimes as sudden cardiac death. Case summary We report on the case of a 67-year-old woman who presented with features of ST-elevation myocardial infarction treated with fibrinolysis. The patient showed to have obtuse-marginal SCAD, which was misdiagnosed as fibrinolysis caused lysis of a coronary thrombus. The patient had moreover all other features of TS. Discussion This case report teaches important information about SCAD. The association between SCAD and TS are discussed.
Fatigue assessment through non-invasive physiological monitoring in military performance: protocol for a systematic review

During military operations, soldiers often encounter extreme environmental, metabolic and neuropsychiatric conditions, which combined lead to a fatigue status that can cause serious physiological impairments, decreasing military performance on the battlefield. Comprehensive studies in realistically stressful environments are essential to expand the knowledge regarding the consequences of real-life stress exposure, facilitate development of operationally-useful techniques and promote the conception of improved treatments. Therefore, a systematic review is proposed to obtain relevant information about fatigue assessment through multiple physiological parameters in the military context, to focus on determining the associations between fatigue and physiological response in order to plan in the future adequate interventions to prevent related negative consequences. Thus, following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses Protocols (PRISMA-P) Statement, this systematic review protocol was elaborated in order to present adequate guidelines to develop a research that can provide appropriate results to fulfil the sought objective. Five databases will be accessed (SCOPUS, PubMed, Science Direct, Medline and Web of Science) and a total of 9 combinations of keywords will be used. This protocol is registered in PROSPERO under the code of PROSPERO CRD42018105833.
Carotid Intima Media Thickness as a Surrogate Measure for Cardiovascular Disease in Rheumatoid Arthritis: Literature Review

Rheumatoid arthritis (RA) is consider as an independent cardiovascular (CV) risk factor and it is associated with increased cardiovascular disease (CVD) mortality and morbidity. Also, RA patients have increased risk of sub-clinical vascular disease compared to their matched controls as shown by high prevalence of carotid artery disease. This subclinical vascular disease was evaluated using the carotid artery intima-media thickness (cIMT) as measured non-invasively using B-mode ultrasound and has been proposed as an early manifestation of atherosclerosis. This literature review aims at analysing the role of cIMT in investigating the subclinical atherosclerosis in RA. *Correspondence to: Suad Hannawi, Associate Professor, Ministry of Health and Prevention, United Arab Emirates, E-mail: suad1@ausdoctors.net
The Maintenance of Genetic Variation by Environmental Selection

The Maintenance of Genetic Variation by Environmental Selection by Cheng-Ruei Lee Department of Biology Duke University Date:_______________________ Approved: ___________________________ Thomas Mitchell-Olds, Supervisor ___________________________ Philip Benfey ___________________________ Mohamed Noor ___________________________ Mark Rausher ___________________________ John Willis An abstract of a dissertation submitted in partial fulfillment of the requirements for the degree of Doctor of Philosophy in the Department of Biology in the Graduate School of Duke University 2013 Copyright by Cheng-Ruei Lee 2013
A visual feedback system for full-body motion analysis from inertial sensor data

Inertial sensor data cannot be used to directly display kinematic motion parameters. In this research, we therefore developed a processing pipeline for the provision of visual motion feedback from inertial sensor data. Following the computation steps of the presented system pipeline, it is possible to determine full-body motion kinematics that can then be animated as moving figures. Data analysis showed that the accuracy of the estimated body kinematics is within few degrees of deviation from the actual data, enabling a use of the system in future applications such as mobile training tools. ; ;
Lipedema: a clinical entity

Lipedema is a chronic, progressive disorder of adipose tissue, found almost exclusively in women, that involves disproportionate subcutaneous fat depositions, leading to progressive and symmetric enlargement of the legs. The condition usually appears at puberty or in the third decade of life. Many patients report a family history of such disorder. The diagnosis is usually based on the physical examination and medical history. If left untreated, lipedema may result in secondary lymphatic dysfunction, physical impairment and mental problems, leading to significant damage to patient’s quality of life. The condition is frequently misdiagnosed as lymphedema or mistreated as obesity. Other than that, the differential diagnosis includes chronic venous insufficiency, constitutional variability of the legs, lipohypertrophy, Dercum’s disease, Madelung’s disease. The treatment options include diet and compression therapy, conservative treatment of secondary edema and surgical interventions. There is an urgent need for further studies on the pathogenesis of lipedema, epidemiology, diagnostic criteria and possible curative treatment.
Acute myocardial infarction in an elderly patient treated for lung cancer

A www.oncoreview. pl AbstrAct There is a growing number of elderly patients, so it is necessary to create new standards of oncologic care for such individuals in order to provide them with the best possible treatment. An elderly woman was treated for locally advanced small-cell lung cancer. Due to the suspicion of coronary disease, arterial hypertension and age, anti-cancer treatment with carboplatin and etoposide was recommended. When carboplatin infusion came to a stop, signs of myocardial infarction in ECG as well as elevated levels of troponin I were reported. Originally, non-invasive treatment was introduced, but several days later three DES stents were placed in coronary arteries. An attempt was made to treat the patient with cisplatin and etoposide, after which respiratory failure, tumor lysis syndrome and pancytopenia occurred. That is why chemotherapy was discontinued at the time. The patient’s tumor area and brain was irradiated. 16 months later, she is still alive without signs of disease progression. New oncologic standards should be elaborated in order to ensure appropriate treatment for elderly patients.
Characterization of 8‐Epiprostaglandin F2α as aMarker of Amyloid β‐Peptide‐Induced Oxidative Damage

Abstract : The amyloid β‐peptide (Aβ) is a major component of the neuritic plaques that are a defining histological characteristic of Alzheimer's disease. Aβ can be directly toxic and pro‐inflammatory to cells in vitro. Numerous reports have shown that oxidative damage and reactive oxygen species play a role in Aβ‐mediated neurotoxicity. 8‐Epiprostaglandin F2α (8‐isoprostane) is a well characterized product of lipid peroxidation that is formed nonenzymatically in cell membranes following an oxidative insult. We report a time‐ and concentration‐dependent increase in 8‐isoprostane levels in rat hippocampal cultures treated with Aβ(1‐40) or hydrogen peroxide. As evidence that 8‐isoprostane production is part of an Aβ toxic pathway, alkaline‐treated peptide, which shows minimal toxic activity, resulted in greatly attenuated 8‐isoprostane production. Although the increase in 8‐isoprostane levels preceded cell death, exogenously added 8‐isoprostane had no cytotoxic effects. The antioxidants vitamin E and propyl gallate attenuated Aβ‐induced 8‐isoprostane formation yet had no effect on Aβ‐induced lactate dehydrogenase release. Neither vitamin E nor propyl gallate had any effect on Aβ's ability to adopt a β‐pleated sheet structure and deposit on cells as determined by thioflavine S fluorescence. We conclude that 8‐isoprostane is an indicator of Aβ‐induced damage but not necessarily a mediator of Aβ‐induced neurotoxicity. Also, 8‐isoprostane could be a useful marker for assessing oxidative damage in the CNS.
Eficácia da hidroterapia no tratamento de crianças com paralisia cerebral: revisão de bibliografia

Objective: this review of the literature has focused on the efficacy of the hydrotherapeutic approach in children with cerebral palsy, especially its influence on strength, flexibility, spasticity, respiratory capacity, range of motion, balance and basic motor skills for functional mobility. Methodology: a computerized search was conducted in Pubmed / Medline, EBSCO, ScienceDirect and PEDro and B-on databases. The selection of the studies was carried out according to the inclusion and exclusion criteria. Results: 9 experimental studies were included. From the analyzed articles, 7 evaluated the basic motor skills, 3 assessed the respiratory capacity, 3 assessed spasticity, 1 assessed flexibility, 1 assessed strength, 1 assessed range of motion and 1 assessed balance. Conclusion: By analyzing the studies found, we can conclude that hydrotherapy seems to be effective in the treatment of children with cerebral palsy, especially in the components of spasticity, respiratory capacity and basic motor skills. However, although it seems to be equally effective in increasing strength, balance, range of motion and flexibility, the data collected by us does not allow us to reach a clear conclusion about the effects of hydrotherapy in children with cerebral palsy.