Miracle-dz/UniFAR-FTUs huggingface dataset:
Sequence Analysis and Modeling of Antimicrobial Peptide from Goat Milk Protein Hydrolyzed by Bromelain

Hydrolysis of goat milk protein by bromelain generates fractions <10 kDa which act as antimicrobe. The fractions contain some peptides that not all were biologically active. Sequence analysis and modeling of the peptides sequences are important to predict their potential bioactivities. The aims of this study were to obtain physicochemical and structure prediction of peptides and their relation with antimicrobial activity. The study was conducted by sequencing of selected fraction in the electrophoresis gel, analyzing and modeling. Analysis of the peptide showed that peptide VLVLDTDYK that predicted from β-lactoglobulin sequence had similar sequence with antimicrobial peptide indolicidin which active to Gram positive bacteria. Peptide LVNELTEFAK was potent to be antimicrobial peptide with therapeutic index 28.69. Modeling of the peptide showed that peptide LVNELTEFAK was able to form helix which important for interaction with microbial membrane. Replacing 2 nd amino acid Valine (V) to Alanine (A) and 4 th amino acid Glutamic acid (E) to Serine (S) might able to increase the therapeutic index to 94.91. Based on the result, peptide LVNELTEFAK potent to be antimicrobial peptide and replacing certain amino acid was able to increase therapeutic index and its antimicrobial activity.
Active back thrust in the eastern Taiwan suture revealed by the 2013 Rueisuei earthquake: Evidence for a doubly vergent orogenic wedge?

Rapid exhumation of 3–10 mm/yr of the Taiwan metamorphic range is often explained as the unroofing of the retrowedge of a doubly vergent mountain belt. Yet, to date, the Central Range fault forming the boundary of the retrowedge has displayed no definitive evidence for recent seismic activity and no unambiguous geomorphic expression over much of the fault. The 2013 M6.4 Rueisuei reverse‐faulting earthquake nucleated at the eastern boundary of the retrowedge and appears to illuminate the west dipping Central Range fault. We estimate the fault geometry and coseismic slip distribution using a uniform stress drop slip inversion and surface displacements derived from GPS and strong‐motion data. We identify a ~42° dipping blind reverse fault, consistent with the previously proposed buried Central Range fault beneath the highly active Longitudinal Valley fault. This earthquake may be the first indication that rapid exhumation and uplift occur along a distinct fault structure bounding the eastern margin of the Taiwan retrowedge.
The Outcome of Postnatal Exercise on Depressed Women Six to 16 Weeks after Delivery in Sukabumi City, 2014: Pre and Post Intervention Study

Evidence shows that psychic disturbances among women during pregnancy and postnatal period causes depression syndrome. Risk factor of postnatal depression includes depression and anxiety and stressful life experience during that risky period. Statistic from the city of Sukabumi indicated the unavailability of data on post natal depression among women. The study question is to evaluate the outcome of exercise among depressed post natal women in Sukabumi city in 2014, during six to sixteen weeks after delivery. The study design is pre-and post-outcome evaluation of post natal exercise intervention. Out of 120 target population obtained from the main Cross Sectional Survey, it was selected study sample of 14 depressed women. A regime of post natal exercise was given to the sample, consisted of postnatal exercises for 10 weeks @ 3 sessions per week or 30 sessions with 30-50 min exercise per session done in the morning before 10 O’clock and in the afternoon after 3 p.m. The outcome variable is EPDS score before and after intervention of post natal exercise. The cut-off point to determine possible depression is EPDS score of ≥10. Univariate analysis was conducted on socio-demographic characteristics of the sample. Bivariate analysis was done to test a null hypothesis that EPDS is the same pre-and post-exercise, assuming that no other variables confound the intervention. The paired t-test results indicated that the EPDS decreased significantly 7.6 points (p<0.05) after 10 weeks from 13.15 (10.66, 15.64) down to 5.55 (4.20, 6.90). After 10 weeks of postnatal exercise conducted, out of 14 subjects there was one subject who remained depressed, but the other 13 women were normal (p<0.05). Software used was SPSS v17 trial version. The study infers that postnatal exercise routinely and regularly may be promoted to be conducted by local health services.
On the connection between mode II and mode III effective thresholds in metals

Closure-free long cracks under the remote mode III loading grow in a more complicated way than those under the remote mode II. For bcc metals, a coplanar in-plane spreading of tongues driven by the local mode II loading components at crack-front asperities prevails while twisting of crack-front segments to mode I, often leading to factory-roof morphology, is typical for other materials. In bcc metals, therefore, the formulation of a quantitative relationship connecting effective thresholds in modes II and III demands to calculate the local mode II components of stress intensity factors at typical asperities of a crack front loaded in the remote mode III. Therefore, a numerical model of a serrated crack front was created and the results were compared with experimentally determined ratio of mode II and III effective thresholds for the ARMCO iron. Although the calculated crack-front roughness needs an experimental verification, the preliminary results indicate that the model can provide a quantitative explanation of the experimentally observed ratio of mode II and mode III effective thresholds in bcc metals.
A note on the asymptotic equivalence of jackknife and linearization variance estimation for the Gini coefficient

The Gini coefficient (Gini 1914) has proved valuable as a measure of income inequality. In cross-sectional studies of the Gini coefficient, information about the accuracy of its estimates is crucial. We show how to use jackknife and linearization to estimate the variance of the Gini coefficient, allowing for the effect of the sampling design. The aim is to show the asymptotic equivalence (or consistency) of the generalized jackknife estimator (Campbell 1980) and the Taylor linearization estimator (Kovac? evic´ and Binder 1997) for the variance of the Gini coefficient. A brief simulation study supports our findings
A RAPID RP-HPLC METHOD DEVELOPMENT AND VALIDATION FOR THE QUANTITATIVE ESTIMATION OF DABIGATRAN ETEXILATE MESYLATE IN CAPSULES Original Article

Objective: To develop a rapid, sensitive, accurate, precise and linear Reverse Phase High Performance Liquid Chromatographic (RP-HPLC) method and validate as per ICH guidelines for the quantitative estimation of Dabigatran etexilate mesylate in capsules. Methods: The optimized method uses a reverse phase column, Waters Symmetry C18 (250 X 4.6 mm; 5μ), a mobile phase of tri ethylammonium phosphate buffer (pH 2.5):acetonitrile in the proportion of 40:60 v/v, flow rate of 1.0 ml/min and a detection wavelength of 313 nm using a UV detector. Results: The developed method resulted in Dabigatran etexilate mesylate eluting at 2.44 min. It exhibited linearity in the range 15-45μg/ml. The precision is exemplified by relative standard deviation of 0.05%. Percentage mean recovery was found to be in the range of 98-102, during accuracy studies. The limit of detection (LOD) and limit of quantitation (LOQ) was found to be 39. 19μg/ml and 118. 88μg/ml respectively. Conclusion: A sensitive, rapid, accurate, precise and linear RP-HPLC method was developed and validated for the quantitative estimation of Dabigatran etexilate mesylate in capsules as per ICH guidelines and hence it can be used for the routine analysis in various pharmaceutical industries.
RF System Modeling for the CEBAF Energy Upgrade

An RF system model, based on MATLAB/SIMULINK, has been developed for analyzing the basic characteristics of the low level RF (LLRF) control system being designed for the CEBAF 12 GeV Energy Upgrade. In our model, a typical passband cavity representation is simplified to in-phase and quadrature (I&Q) components. Lorentz Force and microphonic detuning are incorporated as a new quadrature carrier frequency (frequency modulation). Beam is also represented as in-phase and quadrature components and superpositioned with the cavity field vector. Signals pass through two low pass filters, where the cutoff frequency is equal to half of the cavity bandwidth, then they are demodulated using the same detuning frequency. Because only baseband I&Q signals are calculated, the simulation process is very fast when compared to other controller-cavity models. During the design process we successfully analyzed gain requirements vs. field stability for different superconducting cavity microphonic backgrounds and Lorentz Force coefficients. Moreover, we were able to evaluate different types of a LLRF system’s control algorithm: GDR (Generator Driven Resonator) and SEL (Self Excited Loop) [1] as well as klystron power requirements for different cavities and beam loads.
Recognition of musical chord notes

We developed a new algorithm for automatic recognition of musical chord notes. In the chord recognition field, we often refer to the “Chord Spectrum”, that is the chord representation in the frequency domain. The main concept on which the “chord recognition” theory is based is that we need to find similar groups of sinusoidal tones (tone patterns) belonging to the chord spectrum, through which we can describe the chord as an acoustic profile, with the help of “generative subspectra”. The work done by A. Tanguiane during last decade was the starting point to our study that considers chords played by one or more instruments. In his research, Tanguiane described the chord features and used the information taken from the autocorrelation of chord frequency components to recognize it. He considered that partials forming the chord was equally spaced in a logarithmic way in the frequency domain, implying equal distances correspond to equal musical intervals. To obtain the components equally spaced in a logarithmic way, we use the QFT (Q-constant Fourier Transform), introduced by J.C. Brown in 1991, and also used for the recognition of the fundamental frequency of each note. The QFT allows to show the energy of the singular frequencies in a logarithmic scale spectrum. Autocorrelation is evaluated over the components of the QFT that exceed a certain threshold value. The developed algorithm allows us to obtain good results both for recognition of two, three and four notes chords.
Computer-assisted analysis of bone volume for sinus augmentation procedure

The objectives of this study were to determine the volume of bone required prior to a sinus graft using two different methods, to compare it to the actual volume used during surgery and to evaluate a segmentation technique in quantifying the volume of a xenograft on the post-operative cone beam computed tomography (CBCT) slices. CBCT data from 11 CBCT scans for 11 patients (6 males, 5 females) requiring 13 lateral augmentation procedures were imported to Simplant Pro 15® (Materialise, Leuven, Belgium) in DICOM format. Residual ridge height (RRH) was measured for each implant site as well as mucosal thickness (MT). MT was classified by grades (1 to 4). Simulation of implant placement for each site was realized and the graft volume was pre-operatively calculated by a semi-automatic segmentation (SAS) technique and another automatic Simplant sinus graft (SSG) technique. All patients underwent a lateral sinus augmentation surgery 3 to 12 weeks after the initial CBCT scan. The volume of the bovine bone grafting material (BBM) particles was quantified during the surgery (Vr) for all patients and on immediate post-operative CBCT scans (CBCT-V) for 7 patients. With a mean augmentation of 9.45 ± 1.72 mm, the calculated volumes were 2.243 ± 0.962 mm3 and 2032 ± 0.843 mm3 for the SAS and SSG methods, respectively. Percent variation between Vr and SAS volume was significant (22.4%) and non-significant (4.5%) between Vr and SSG volume. In cases with MT grade 1 & 2, no difference was found between Vr and SAS volume. No difference was found between Vr (1.918 ± 1.118 mm3) and CBCT-V (1.979 ± 1.108). In conclusion, the results showed that the use of the Simplant® software was effective in determining the required graft volume for the surgery, the volume measurements with the SSG were more accurate than the SAS and the quantification of BBM particles on CBCT data sets was reliable and accurate with the segmentation technique used.
Did stick insects really regain their wings?

In a recent issue of Nature, Whiting et al. (2003) report a surprising and novel result: the re-evolution of insect wings from wingless ancestors in Phasmatodea (stick insects). If true, this represents an important advance in our understanding of insect and gene evolution. It overturns a long-held notion that wings evolved just once in insects and have been lost many times. The allegedly re-evolved wings have exactly the same detailed structure as other insect wings (Whiting et al., 2003, their Fig. 1b) and if this feature truly has been regained in stick insects it would demonstrate a remarkable maintenance of ‘wing genes’ despite inactivation of the developmental pathway over long periods of evolutionary time. Whiting et al.’s conclusions have already been promulgated in the popular literature (New Scientist, Scientific American, The New York Times, Anon, 2003a, b, c) but before this extraordinary evolutionary scenario reaches the entomology textbooks a re-examination is in order. Two lines of evidence are essential to Whiting et al.’s wing re-evolution hypothesis: (1) the topology in their stick insect phylogenetic tree, and (2) the distribution of wing/wingless transformations on that tree. The latter issue, character optimization, is addressed here. Our reappraisal of the evidence convinces us that Whiting et al. have overstated significantly the probability of wing re-evolution in stick insects. When this is taken into account we see no grounds for overturning the traditional view of stick insect evolution.
Information Privacy and Loneliness on the Impact of Virtual Communities Users' Voice

One motivation for virtual communities users is to interact with less familiar community members. This is known as the weak tie concept. Previous studies are based on utilitarian and hedonic aspects for virtual communities in the past, but few researches focus on the personal factors. In the context of virtual communities, this study takes information privacy and loneliness for the exogenous variables, through self-disclosure intermediary, to explore the impact on the virtual communities users’ voice. To apply of structural equation modeling analysis, this study shows that (1) Users’ general privacy concern has a significant and negative effect on self-disclosure and privacy protection belief has a significant and positive effect. (2) Only romantic loneliness negatively affects users’ self-disclosure in virtual communities. (3) Self-disclosure amount and self-disclosure depth have significantly positive affect on voice.
MODELING OF BIOMASS PYROLYSIS FOR HYDROGEN PRODUCTION: THE FLUIDIZED BED REACTOR

A numerical study is performed in order to evaluate the performance and optimal operating conditions of suidized bed pyrolysis reactors used for condensable tar production from biomass. For this purpose, a previously validated biomass particle pyrolysis model is coupled with a detailed hydrodynamic model for the binary gas particle mixture. The kinetics scheme is based on superimposed cellulose, hemicellulose, and lignin reactions. Any biomass feedstock can be simulated through knowledge of its initial mass composition with respect to these three primary components. The separately validated hydrodynamic model is based on a three s uid model (gas, sand, and biomass) derived from the kinetic theory of granular sows. Separate transport equations are constructed for each particle class, allowing for the description of such phenomena as particle segregation and for separate temperatures for each particle class. The model is employed to investigate the effect of various operating conditions on the efÞciency of tar collection in suidized bed reactors. Results indicate that, at Þxed particle size, the operating temperature is the foremost parameter insuencing tar yield. The biomass feed temperature, the feedstock, and s uidization velocity magnitude, all have minor impact on the yield. The particle diameter has a considerable insuence on the shorttime tar yield, but it is inferred that it may a more moderate insuence on the steady-state tar yield.
Scale and geometry effects on heat-recirculating combustors

A simple analysis of linear and spiral counterflow heat-recirculating combustors was conducted to identify the dimensionless parameters expected to quantify the performance of such devices. A three-dimensional (3D) numerical model of spiral counterflow ‘Swiss roll’ combustors was then used to confirm and extend the applicability of the identified parameters. It was found that without property adjustment to maintain constant values of these parameters, at low Reynolds number (Re) smaller-scale combustors actually showed better performance (in terms of having lower lean extinction limits at the same Re) due to lower heat loss and internal wall-to-wall radiation effects, whereas at high Re, larger-scale combustors showed better performance due to longer residence time relative to chemical reaction time. By adjustment of property values, it was confirmed that four dimensionless parameters were sufficient to characterise combustor performance at all scales: Re, a heat loss coefficient (α), a Damköhler number (Da) and a radiative transfer number (R). The effect of diffusive transport effect (i.e. Lewis number) was found to be significant only at low Re. Substantial differences were found between the performance of linear and spiral combustors; these were explained in terms of the effects of the area exposed to heat loss to ambient and the sometimes detrimental effect of increasing heat transfer to adjacent outlet turns of the spiral exchanger. These results provide insight into the optimal design of small-scale combustors and choice of operation conditions.
The Quality of Exports based on China-India and Its Comparative Research---- From the perspective of trade in value added

This paper compares the export quality of China and India based on the perspective of trade in value added. First, we calculate the volume of value added of exports in China and India from the aspect on total number, industrial number and bilateral number. Then comparing the quality of exports between China and India from three dimensions. Result shows that the proportion of exports in value added of China and India continue to decrease compared with the total exports, and the proportion of value added of exports in these two countries are equal almostly; By the view of industrial level, the proportion of China's exports in value added are relatively balanced among different industries, while India's exports in value added mainly concentrated on agricultural sector, nature resource industries and financial services, software information industries. Take on the comparasion of second dimension, China has slight advantages; From the third dimension of market distribution, China's export market tends to be decentralized and the dependence on a certain market decreased by time goes. Forming a striking contrast, Indian market of export turns to be more and more concentrated. So the overall quality of China's export is better than that of India.
DPIV MEASUREMENT AND CFD SIMULATION OF VISCOUS FLUID FLOW IN STIRRED TANK AGITATED BY RUSHTON TURBINE

Mixing, achieved mostly by mechanically stirring, is one of the most important unit operation processes in chemical and related industries. The problem of design and scale-up of stirred tanks has been tackled mainly by means of semi-empirical methods.Measurement and numerical simulation of viscous fluid in a stirred tank is still unsufficient and further development is needed.In this paper, computational fluid dynamics (CFD) simulation and digital particle image velocimetry (DPIV) measurement have been carried out to study the flow field of viscous fluid in a stirred tank agitated by a four-blade Ruston turbine.The working medium is a mixture of water and glycerine with various concentrations.The results show the mean velocity, turbulent energy, vorticity and circle flux of the fluids as well as the change of flow patterns with the fluid viscosity.CFD code of CFX with sliding grids was used to simulate the flow field.The k-e model and laminar model was selected as the models of simulation.The CFD simulations were compared with the experimental DPIV data.The result shows that the CFD simulations can reflect the flow of the viscous fluid in a stirred tank.
Analisis Framing : konstruksi, ideologi dan politik media

Buku ini memberikan peta teoritikmetodologis yang luas mengenai analisis framing. Untuk melengkapi dalam buku ini disertakan juga contoh penerapan analisis farming atas berbagai kasus yang pernah ditawarkan media di tanah air. Analisis Framing merupakan salah satu model analisis alternatif yang bisa mengungkapkan rahasia di balik perbedaan, bahkan pertentangan media dalam mengungkapkan fakta. Melalui analisis framing akan dapat diketahui siapa mengendalikan siapa, mana lawan mana kawan, mana patron mana klien, siapa diuntungkan siapa dirugikan, siapa membentuk dan siapa dibentuk,dan seterusnya.
Quality of virgin olive oil as influenced by origin area.

To elucidate the weight and the influence of the origin area on the analytical and compositional variables of olive oil, an investigation was carried out. Five Italian geographical zones were chosen. They were in the neighbour of the: (i) Faculty of Agriculture of University of Perugia (UNI-PG); (ii) the Olive Growing Institute-National Research Council of Perugia (NRC-PG); (iii) the Experimental Olive Growing Institute of Spoleto (EOI-SPOL); (iv) the Agricultural Technical Institute of Pescia (ATI-PES); and (v) the Faculty of Agriculture of University of Florence (UNI-FL). From these areas, Frantoio, Leccino and Moraiolo olive variety samples were taken, which were processed by a mini oil-mill. The research results showed that the quality, typicality and shelf-life parameters and the flavour of the oils were largely influenced by the origin zone, i.e., by the climatic and pedologic factors of the production environment. The influence exerted on some oil constituent groups, as phenols, tocopherols, aromatic volatile compounds, and fatty acids, should be emphasized as these components are closely related to the quality and typicality of product. Some oil genuineness parameters were affected as well by the environmental variables.