Miracle-dz/UniFAR-FTUs huggingface dataset:
HealthCare MisInformation Detection on Social Media

Recently, the employment of social networks like Facebook Associate in Nursing and Twitter became an indivisible part of our daily lives. However, whereas folks get pleasure from social networks, several deceptive activities like faux news or rumors will mislead users into basic cognitive process info. Besides, spreading a large quantity of info on social networks has become a world risk. Therefore, info detection (MID) in social networks has gained an excellent deal of attention Associate in nursing is taking into account a rising space of analysis interest. there's a requirement to develop automatic solutions which will aid each consultant and non-experts in differentiating between reliable and unreliable health data as a result of tending is one of the foremost vital and pressing topics in our society. several malicious things regarding health square measure unfold that square measure unreliable and folks believe that to mislead that data.
Identification of Mungbean yellow mosaic India virus infecting cucumber in Oman

Cucumber (Cucumis sativus) is a widely cultivated plant in the family Cucurbitaceae that is grown as greenhouse crop in Oman. During a recent survey for begomoviruses, whitefly infestation was observed in two greenhouses of cucumber in the Barka region. Plants were exhibiting a foliar yellow mosaic and crumpling, symptoms typical of begomovirus infection (Supplementary Figure 1), with an incidence of 50-60 %. Leaves from four symptomatic plants were collected, two plants from each greenhouse, as well as leaves from two apparently healthy (symptomless) plants, one from each greenhouse. Electron microscopy analysis of negatively stained sap samples showed the presence of geminate (twinned quasi-icosahedral) particles of ~18-20x30 nm in samples from symptomatic but not non-symptomatic plants, suggesting the presence of a geminivirus. Nucleic acids were extracted from leaf samples (Porebski and Bailey 1997) and used in PCR with primers to the conserved domain of the coat protein of begomoviruses (Brown et al.
Effect of nutrient limitation and light in the production of polyhydroxybutyrates and glycogen by cyanobacteria cultivated in wastewater

Non-degradable plastics are a serious environmental problem. The use of living resources to produce biodegradable plastics could be a possible solution. Polyhydroxybutyrates (PHB), which are polymers with similar properties to polypropylene, and glycogen, which can be converted into bioethanol, are produced by cyanobacteria and other microorganisms. Cyanobacteria have the advantage of accumulating these substances using only CO2 and solar energy. Wastewater treatment could be used as a culture medium for cyanobacteria to reduce the bioplastics production costs. The main objectives of this work are to study the use of cyanobacteria as tertiary wastewater treatment, the effect of nutrient limitations and light hours on the accumulation of PHB and glycogen, and the best way to operate a reactor to select cyanobacteria against green algae. It has been possible to eliminate 64,8% of the nitrogen and 70,5% of the phosphorus coming from the secondary treatment and the digestate. Proving the ability of cyanobacteria to remove contaminants. A maximum glycogen concentration of 838 mg / L was obtained under nitrogen limitation and 12 h light conditions and a PHB of 104,2 mg / L under phosphorus limitation and 24 h light conditions. Therefore, it can be deduced that nitrogen limitation has more effect on glycogen accumulation, and phosphor on PHB. However, according to the defined economical Key performance indicator (KPI) the product benefits do not justify the lighting expenses. Finally, it can be said that the optimal cultivation conditions are limitation of phosphor and 12h light per day.
Modified hCFTR mRNA restores normal lung function in a mouse model of cystic fibrosis

Being a classic monogenic disease, gene therapy has always been a promising therapeutic approach for Cystic Fibrosis (CF). However, numerous trials using DNA or viral vectors encoding the correct protein resulted in a general low efficacy. In the last years, chemically modified messenger RNA (cmRNA) has been proven to be a highly potent, pulmonary effective drug. We thus explored the expression of human (h)CFTR encoded by hCFTR cmRNA in vitro, analyzed by flow cytometry and Western Blot and its function with a YFP assay. Very similar effects could be observed in vivo when hCFTR cmRNA was assembled with Chitosan-coated PLGA to nanoparticles (NPs) and intratracheally (i.t.) or intravenously (i.v) injected, the latter one as an alternative administration route to circumvent the clogged airways of CF patients. This significantly improved lung function, which suggests that hCFTR cmRNA-NPs are a promising therapeutic option for CF patients independent of their CFTR genotype.
Regional Conservation Implications of Green Turtle (Chelonia mydas) Genetic Stock Composition in China

Abstract Sea turtles are globally endangered and face anthropogenic threats, such as direct harvest, bycatch, and habitat degradation. Genetic studies help identify connectivity between nesting and foraging grounds for conservation and management. However, information on genetic stock composition of green turtles (Chelonia mydas) in the South China Region (including Hong Kong, Guangdong Province, and Taiwan) is severely limited. In this study, mixed stock analysis based on the 760-bp mitochondrial DNA (mtDNA) control region of green turtles (n = 110) revealed that the primary source rookeries in the Pacific contributing to foraging green turtle aggregations in the South China Region were Peninsular Malaysia, Yap in the Federated States of Micronesia, Aru of Indonesia, Sulu Sea, northeastern Borneo, Republic of Marshall Islands, Wan-an of Taiwan, and the central Ryukyu and Yaeyama of Japan. This study is the first to investigate and report the source nesting populations of a relatively large number of foraging green turtles in the region. The genetic results also indicate possible use of coastal Guangdong, the Taiwan Strait, and the East China Sea as habitat by pelagic-phase green turtles hatched from nesting beaches in Taiwan and mainland China. As a precautionary approach for effective sea turtle conservation, conservation and management of each distinct green turtle source rookery as well as foraging aggregations sourced from multiple natal origins in the South China Region is needed to preserve genetic diversity for the species. Anthropogenic threats to nesting and foraging habitats and migratory pathways, such as direct take for trade and fishery impacts, should be thoroughly assessed and effectively mitigated by regional collaboration to sustain these populations.
Interações intra- e intermoleculares dos begomovírus e seus efeitos na adaptação viral e na maquinaria celular do hospedeiro

ix INTRODUÇÃO . 1 2. REVISÃO DE LITERATURA . 6 2.1. A família Geminiviridae . 6 2.2. Replicação viral . 9 2.3. Movimento do vírus na planta . 10 2.4. Mecanismos de geração de variabilidade genética na família Geminiviridae . 12 2.5. Interações geminivírus-hospedeiro . 16 2.6. Interferência dos begomovírus no ciclo celular . 20 2.7. Detecção de interação entre proteínas i vivo via purificação por afinidade em tandem (Tandem affinity purification , TAP) . 23 3. LITERATURA CITADA . 26 Capítulo 1. Recombination and pseudorecombination driving the evolution of Tomato severe rugose virus (ToSRV) and Tomato rugose mosaic virus (ToRMV): Two recombinant DNAA components sharing the same DNA-B . 46 Abstract . 47. 47 Introduction . 48 Material and Methods . 51 Viral isolates and plant material . 51
Experimental warming reduces the diversity and functional potential of the Sphagnum microbiome

Climate change may reduce biodiversity leading to a reduction in ecosystem productivity. Despite numerous reports of a strong correlation of microbial diversity and ecosystem productivity, little is known about the warming effects on plant associated microbes. Here we explore the impact of experimental warming on the microbial and nitrogen-fixing (diazotroph) community associated with the widespread and ecologically relevant Sphagnum genus in a field warming experiment. To quantify changes in the abundance, diversity, and community composition of Sphagnum microbiomes with warming we utilized qPCR and Illumina sequencing of the 16S SSU rRNA and nifH gene. Microbial and diazotroph community richness and Shannon diversity decreased with warming (p<0.05). The diazotroph communities shifted from diverse communities to domination by primarily Nostocaceae (25% in control samples to 99% in elevated temperature samples). In addition, the nitrogen fixation activity measured with the acetylene reduction assay (ARA) decreased with warming treatment. This suggests the negative correlation of temperature and microbial diversity corresponds to a reduction in functional potential within the diazotroph community. The results indicate that climate warming may alter the community structure and function in peat moss microbiomes, with implications for impacts to host fitness and ecosystem productivity, and carbon uptake potential of peatlands.
Steep Sub-threshold Slope Si and InGaAs Dopingless TFET: TCAD and ADS Simulation Based Investigation for Digital/Analog Applications

In this paper, a comparative study is presented for silicon and InGaAs-based DL-TFET for different circuit designs. Firstly, the silicon DL-TFET result is calibrated and its results are compared with InGaAs-based DL-TFET, among which, InGaAs-based DL-TFET shows better performance parameters. Hence, for designing the circuits, the Verilog-A model is used, in which the look-up table approach is adopted for designing the netlist. Subsequently, different digital and analog circuits are designed using both silicon and InGaAs-based DL-TFET. The CMOS inverter and 3-stage ring oscillator are investigated which shows the lowest propagation delay of the order of 3.1 ns and 0.39 ns respectively for InGaAs-based DL-TFET. Similarly, in an analog circuit, a common source amplifier is analyzed for variations in different circuit components; and it shows the highest gain of 2.98 for InGaAs-based DL TFET at $V_{\text {DD }} 0.8 ~\mathrm{V}, \mathrm{R}_{\mathrm{B}}$ of $3.2 \mathrm{K}\Omega$, and $\mathrm{R}_{\mathrm{L}}$ of $1 \mathrm{M}\Omega$. Hence, InGaAs-based DL-TFET shows the best circuit-level performance in comparison with silicon.
The Effects of Using Sodium Alginate Hydrosols Treated with Direct Electric Current as Coatings for Sausages

We investigated the effect of sodium alginate hydrosols (1%) with 0.2% of NaCl treated with direct electric current (DC) used as a coating on microbial (Total Viable Counts, Psychrotrophic bacteria, yeast and molds, Lactic acid bacteria, Enterobacteriaceae), physiochemical (pH, lipid oxidation, antioxidant activity, weight loss, color) and sensory properties of skinned pork sausages or with artificial casing stored at 4 °C for 28 days. Moreover, the cytotoxicity analysis of sodium alginate hydrogels was performed. The results have shown that application of experimental coatings on the sausage surface resulted in reducing all tested groups of microorganisms compared to control after a 4-week storage. The cytotoxicity analysis revealed that proliferation of RAW 264.7 and L929 is not inhibited by the samples treated with 200 mA. Ferric reducing antioxidant power (FRAP) and free radical scavenging activity (DPPH) analyses showed that there are no significant differences in antioxidant properties between control samples and those covered with sodium alginate. After 28 days of storage, the highest value of thiobarbituric acid-reactive substances (TBARS) was noticed for variants treated with 400 mA (1.07 mg malondialdehyde/kg), while it was only slightly lower for the control sample (0.95 mg MDA/kg). The obtained results suggest that sodium alginate treated with DC may be used as a coating for food preservation because of its antimicrobial activity and lack of undesirable impact on the quality factors of sausages.
A potential nutraceutical from Leuconostoc mesenteroides B-742 (ATCC 13146); production and properties

There is an emerging market for functional oligosaccharides for use in foods. Currently, technology for the production of oligosaccharides is limited to extraction from plant sources, acid or enzymatic hydrolysis of polysaccharides or synthesis by transglycosylation reactions. Oligosaccharides also can be produced using a Leuconostoc fermentation and restricting the polymer size by the addition of maltose. Maltose limits the dextransucrase reaction, yielding high concentrations of α-glucooligosaccharides. Branched oligomers produced by this process were found to be readily catabolized by bifidobacteria and lactobacillus but were not readily utilized by either Salmonella sp. , or E. coli, pointing toward their use in intestinal microflora modification. Branched α-glucooligosaccharides were non-competitive inhibitors of α-glucosidase (maltase), an enzyme required for starch or maltodextrin utilization.
Discovery of the New Target for Identification of Mycobacterium tuberculosis

Tuberculosis has been one of the most important infectious diseases in human history, which causes deaths of 2 million people around the world annually (1). Inhalation of 1 3 bacillus Mycobacterium tuberculosis is sufficient for infection with this bacterium. According to the existing reports, almost one-third of the world’s population is infected with M. tuberculosis, although they may not show any symptoms of this disease (2, 3). Due to the spread of HIV epidemics in the world, and emergence of the drug-resistant strains of Mycobacterium tuberculosis (DR-TB), eradication of tuberculosis is impossible (1).
Regulation and ecological relevance of fructosyltransferases in Lactobacillus reuteri

Glycosyltransferases form oligo- and homopolysacchrides from sucrose. The regulation and functionality von glycosyltransferases in two strains of Lactobacillus reuteri, L. reuteri TMW1.106 and LTH5448, was examined. Fructosyltransferases were regulated by sucrose and by environmental conditions. Products formed by fructosyltransferases improved stress resistance towards antimicrobial substances and during freeze-drying. The presence of fructosyltransferases increased competitiveness of L. reuteri in the natural habitats sourdough and mice forestomach. The expression of the glucosyltransferase GtfA of L. reuteri TMW1.106 was not affected by sucrose or environmental conditions. Inactivation of GtfA had no impact on the performance of L. reuteri TMW1.106 neither in sourdough nor in the mice forestomach. Nevertheless, glucosyltransferases might play a role in other ecosystems.
Survey on Algorithms and Techniques for Secure Cloud Database

Cloud computing is a style of computing where massively scalable information technology-enabled capabilities are conveyed ‘as a service’ using computer and Internet technologies to numerous clients. The different safety problems in cloud are scalability, data truthfulness, heterogeneity, data intrusion, non-disclaimer, access control, authentication and authorization. Detecting and preventing data privacy requires a set of different technique, which may include data-privacy recognition, surreptitious malware detection data locking up, and policy enforcement. For cloud database security many techniques and algorithms are provided. This paper reviews different algorithms and techniques to secure cloud computing database.
Association between polymorphisms of DNA repair genes and risk of type 2 diabetes mellitus in the Turkish population

Abstract Objectives DNA repair mechanisms work insufficiently in T2DM patients and hyperglycemia seen in diabetes disturbs the oxidant-antioxidant balance thus cause oxidative damage on DNA. The effects of the DNA repair genes’ have not yet been investigated on diabetes. The aim of this study was to investigate the association between APE1 Asp148Glu and XPG Asp1104His polymorphisms with T2DM in the Turkish population. Material and methods Sixty-five T2DM patients and 54 healthy individuals were included to this study as control. The polymerase chain reaction-restriction fragment length polymorphism techniques were used. Results When the study groups were compared, serum HDL-cholesterol levels were found statistically elevated in the controls. Once the APE1 Asp148Glu polymorphism distribution between the patient and control groups was investigated, the Glu/Glu genotype ratio was found significantly higher in the control group. Furthermore, the Asp/Glu genotype and the Asp allele prevalences were observed to be higher in the patient group. Also, patients with the Asp/Asp genotype had higher serum HDL-cholesterol levels than the others. Conclusion Despite the small number of subjects included, it could be interpreted that the Glu allele of the APE1 Asp148Glu polymorphism might be protective against and the Asp allele may be contributing to the development of diabetes.
Parameter Optimization of Low Order Inertia System Controller Based on PSO Algorithm

In industrial process control, the controller parameters need to be continuously adapted to the working conditions to achieve the best control accuracy requirements, but it still relies on regular manual maintenance updates to solve the problem. In order to improve the accuracy of PID control optimization parameters and traditional optimization methods, this paper identifies a typical second-order control link transfer function based on a dynamic step impulse response method with 92.3% accuracy, proposes a PSO algorithm-based PID controller parameters optimization adjustment method, and verifies the reliability of the optimization parameters by building a process control experiment platform.
On a ‘failed’ attempt to manipulate conscious perception with transcranial magnetic stimulation to prefrontal cortex

It has been reported that continuous theta burst transcranial magnetic stimulation (TMS) to the dorsolateral prefrontal cortex (DLPFC) impairs metacognitive awareness in visual perception (Rounis et al., 2010). Bor et al. (2017) recently attempted to replicate this result. However, the authors modified the experimental design of the original study considerably, meaning that this was not strictly a replication. In some cases, the changes are a priori expected to lower the chance of obtaining positive findings. Despite these changes, the researchers in fact still found an effect similar to Rounis et al.’s, but they claimed that it was necessary to adopt certain criteria to discard ∽30% of their subjects, after which a null result was reported. Using computer simulations, we evaluated whether the subject exclusion criteria Bor et al. adopted was appropriate or beneficial. We found that, contrary to their intended purpose, excluding subjects by their criteria does not actually reduce false positive rates. Taking into account both their positive result (without subject exclusion) and negative result (after exclusion) in a Bayesian framework, we further found that their results suggest a 75% or greater likelihood that TMS to DLPFC does in fact impair metacognition, directly contradicting their claim of replication failure. That lesion and chemical inactivation studies are known to demonstrate positive effects in similar paradigms further suggests that Bor et al.’s alleged negative finding cannot be taken as evidence against the role of the prefrontal cortex in conscious perception in general.
Stay-green and other physiological traits as efficient selection criteria for grain yield under drought stress condition in sorghum (Sorghum bicolor L. Moench)

An experiment was conducted to study the co-efficient of variation, heritability, genetic advance, correlation coefficients and path analysis for yield and other physiological traits of sorghum genotypes under moisture stress condition with the aim of assessing the potential genetic gain. High estimates of heritability and genetic advance as per cent of mean were observed for leaf area index, stay-green score, relative water content, proline, SPAD chlorophyll, plant height and grain yield. Positive and significant correlation of grain yield with leaf area index, stay-green, relative water content, SPAD chlorophyll content and proline were observed. The characters like leaf area index, stay-green, relative water content and SPAD chlorophyll had positive direct effect on single plant yield under drought stress condition at genotypic level. This suggests the possibilities of improvement of these characters through selection for drought tolerance breeding programme.
A Wind Turbine Control Parameter Optimization Strategy for Improving Power System Transient Stability

With the rapid development of new energy, the problems faced by large-scale new energy long-distance outbound transmission are becoming more and more prominent. China’s large-scale wind power bases are mostly located at the end of the grid, and the grid structure is weak, so the voltage stability problems such as transient overvoltage have become one of the main factors limiting the wind power transmission capacity. In this paper, we study the causes of transient overvoltage and the influence of wind turbine control parameters on transient overvoltage after short-circuit faults in large-scale wind power convergence areas, propose an optimization strategy for wind turbine control parameters considering various voltage stability problems, and conduct a simulation to verify it with an actual regional grid. The results show that the optimization strategy proposed in this paper can effectively improve the voltage stability and thus enhance the new energy channel outgoing capability.
Multimodal Recognition of Diverse Peptides by the SH2 Domains of PLCγ1 and SH2B1

Heteronuclear single quantum coherence (HSQC) nuclear magnetic resonance (NMR) experiments offer a rapid and high resolution approach to gaining binding and conformational insights into a protein/peptide interaction. By tracking H and N chemical shift changes over the course of a peptide titration into isotopically labeled protein, amide NH pairs of amino acids whose chemical environment changes upon peptide binding can be identified. When mapped onto a structure of the protein, this approach can identify the peptide-binding interface or regions undergoing conformation changes within a protein upon ligand binding. Monitoring NMR chemical shift changes can also serve as a screening technique to identify novel interaction partners for a protein or to determine the binding affinity of a weak protein/peptide interaction. Here, we describe the application of NMR chemical shift mapping to the study of peptide binding to the Cterminal SH2 domain of PLCγ1.
Validation Repeatability of Measurement of Antibody Response to Ovalbumin in Beef Cattle

The objectives of this experiment were to evaluate the pattern of antibody response to ovalbumin as a test antigen in beef cattle, and to estimate the repeatability of the measurement of that response. Purebred Angus cows and calves were immunized with ovalbumin and later tested for antibody response. Six animals were sampled 7 d post-initial immunization to characterize primary antibody response and at 3, 5, and 7 d post-secondary immunization to characterize secondary antibody response. Increases in level of IgG specific for ovalbumin were more rapid in calves than in cows but gradually, measured levels became similar. Secondary responses were measurable on all specified dates, but primary response was not evident at d 7. Correlations between successive samples on animals indicated that the measurements were repeatable (R = .73) for secondary response. These data indicate that ovalbumin is an acceptable test antigen for eliciting a humoral immune response in beef cattle and that measurement of secondary response to ovalbumin can be evaluated in beef cattle at 5 or 7 d post-secondary immunization.