Miracle-dz/UniFAR-FTUs huggingface dataset:
Determination of amino acids misincorporation in recombinant protein by mass spectrometry

The synthesis of protein according to genetic code of a gene determines the basis of life and a stable proteome is necessary for cell homeostatis. However, errors occur naturally during translation of protein from its mRNA, which varies from 10 -3 to 10 -4 per codon. These errors are more frequent in recombinant protein overexpressed in heterologous hosts and affect protein functionality. The increasing amount of nonfunctional protein is often related to mistranslation of a gene under stress. In the present study, Saccharomyces cerevisiae as a host organism to overexpress E. coli lacZ gene fusion with GST to quantify misincorporation of amino acid in GST-? galactosidase recombinant protein. The yeast was treated with various stressors such as ethanol, chromium (CrO 3 ), and aminoglycoside antibiotic - geneticin (G418) to induce protein aggregation. The misincorporation of amino acids was studied in soluble protein fractions by mass-spectrometry to determine how much misincorporation occur. We found that under experimental stress conditions the misincorporation of amino acids ranges from 5.6 ×10 -3 to 8 × 10 -3 , which represents 60-80 fold higher than reported level. DOI: http://dx.doi. org/10.3329/bjas.v42i1. 15760 Bang. J. Anim. Sci. 2013. 42 (1): 11-19
Evaluation of DRed a Way of Capturing and Structuring Engineering Processes

This paper describes research that was carried out in collaboration with the aerospace group of a major power systems company to evaluate a software tool called DRed that allows engineering designers to document their design rationales. DRed is one of many proposed derivatives of the IBIS concept. DRed allows the issues addressed, answers considered, and associated arguments, both for and against, to be captured graphically. The paper presents an analysis of DRed issues to understand the nature of the questions documented by engineering designers. The frequency of use of pairs of DRed elements is also analysed to understand how engineering designers developed DRed structures. The paper finally compares the design information captured in DRed design folders with that captured in Design Definitions Reports (DDRs) to show how the use of DRed improves the richness of the recorded information.
Theoretical power spectra of mixed modes in low-mass red giant stars

Context. CoRoT and Kepler observations of red giant stars revealed very rich spectra of non-radial solar-like oscillations. Of particular interest was the detection of mixed modes that exhibit significant amplitude, both in the core and at the surface of the stars. It opens the possibility of probing the internal structure from their innermost layers up to their surface throughout their evolution on the red giant branch, as well as on the red clump. Aims. Our objective is primarily to provide physical insight into the mechanism responsible for mixed-mode amplitudes and lifetimes. Subsequently, we aim at understanding the evolution and structure of red-giant spectra along with their evolution. The study of energetic aspects of these oscillations is also important for predicting the mode parameters in the power spectrum. Methods. Non-adiabatic computations, including a time-dependent treatment of convection, are performed and provide the lifetimes of radial and non-radial mixed modes. We then combine these mode lifetimes and inertias with a stochastic excitation model that gives us their heights in the power spectra. Results. For stars representative of CoRoT and Kepler observations, we show under which circumstances mixed modes have heights comparable to radial ones. We stress the importance of the radiative damping in determining the height of mixed modes. Finally, we derive an estimate for the height ratio between a g-type and a p-type mode. This can thus be used as a first estimate of the detectability of mixed modes.
Confirmatory factor analysis of the Hewitt- multi-dimensional perfectionism scale

Various studies on the conceptual framework of perfectionism construct use Hewitt Multi-dimensional Perfectionism Scale (HMPS), as a basic approach. The measure has a prominent role with respect to the theoretical considerations of perfectionism dimensions. This study aimed to evaluate the psychometric properties of the Turkish version of the scale. 479 undergraduate volunteers participated in this study. In this study, demographic questionnaire, Hewitt Multi-dimensional Perfectionism Scale (HMPS), Padua Inventory (PI_R), Obsessive Beliefs Questionnaire (OBQ-44) were administered. The original three factor structure was tested for the Turkish version of the scale by using confirmatory factor analysis. Convergent validity of the measure was evaluated. Internal consistency and 15- day temporal stability were computed in order to assess reliability of the measure. The confirmatory factor analysis replicated the validity of the three factor structure for the data obtained from Turkish sample. The measure has adequate reliability and validity in Turkish students. Key words: Perfectionism, validity, factor analysis, compulsive symptoms, obsessive beliefs.
A Preliminary Analysis of Relationships Between a 1RM Hexagonal Bar Load and Peak Power with the Tactical Task of a Body Drag

Abstract A critical job task for law enforcement officers that should be influenced by strength is the body drag. This study analyzed relationships between absolute and relative strength measured by a one-repetition maximum hexagonal bar deadlift (1RM HBD), with body drags completed with 74.84 kg and 90.72 kg dummies. Twenty recreationally-trained individuals completed the 1RM HBD in one session, with peak power measured via a linear position transducer. Over two subsequent sessions, participants dragged the 74.84 kg and 90.72 kg dummies with two techniques. The first technique followed Californian standards, where participants wrapped their arms around the dummy and lifted it to standing before timing commenced. In the adapted technique, timing included the initial manipulation of the dummy. Participants dragged the dummy as quickly as possible over a 9.75 m distance. Partial correlations and linear regression (controlling for sex; p < 0.05) analyzed relationships between the HBD and body drags. The standard 74.84 kg body drag correlated with every HBD variable (r = -0.477 to -0.666), and was predicted by the absolute 1RM HBD (r2 = 0.467). The adapted 74.84 kg drag correlated with all HBD variables (r = -0.535 to - 0.754), and was predicted by peak power and the 1RM HBD (r2 = 0.758). Both 90.72 kg drags correlated with absolute and relative 1RM HBD (r = -0.517 to -0.670). Strength related to all body drags; peak power may be more important for drags with lighter loads. Strength training should be a focus in law enforcement to enhance drag performance.
Common fixed point theorems for weakly compatible mappings in fuzzy metric spaces

The aim of this paper is to prove a common fixed point theorem for a pair of weakly compatible mappings in fuzzy metric space by using the (CLRg) property. An example is also furnished which demonstrates the validity of our main result. As an application to our main result, we present a fixed point theorem for two finite families of self mappings in fuzzy metric space by using the notion of pairwise commuting. Our results improve the results of Sedghi, Shobe and Aliouche [A common fixed point theorem for weakly compatible mappings in fuzzy metric spaces, Gen. Math. 18(3) (2010), 3-12 MR2735558].
Low-dimensional chaos and fractal properties of long-term sunspot activity

Two primary solar-activity indicators–sunspot numbers (SNs) and sunspot areas (SAs) in the time interval from November 1874 to December 2012 – are used to determine the chaotic and fractal properties of solar activity. The results show that (1) the long-term solar activity is governed by a low-dimensional chaotic strange attractor, and its fractal motion shows a long-term persistence on large scales; (2) both the fractal dimension and maximal Lyapunov exponent of SAs are larger than those of SNs, implying that the dynamical system of SAs is more chaotic and complex than SNs; (3) the predictions of solar activity should only be done for short- to mid-term behaviors due to its intrinsic complexity; moreover, the predictability time of SAs is obviously smaller than that of SNs and previous results.
IDENTIFYING YOUNG STARS IN MASSIVE STAR-FORMING REGIONS FOR THE MYStIX PROJECT

The Massive Young star-forming Complex Study in Infrared and X-rays (MYStIX) project requires samples of young stars that are likely members of 20 nearby Galactic massive star-forming regions. Membership is inferred from statistical classification of X-ray sources, from detection of a robust infrared excess that is best explained by circumstellar dust in a disk or infalling envelope and from published spectral types that are unlikely to be found among field stars. We present the MYStIX membership lists here, and describe in detail the statistical classification of X-ray sources via a “Naive Bayes Classifier. ” These membership lists provide the empirical foundation for later MYStIX science studies.
A new perspective on the third-country effect: The case of Malaysia–US industry-level trade

ABSTRACT Cushman suggested that impact of exchange rate volatility declines after the inclusion of the third-country effect. Like Cushman, when we use a linear analysis, we confirm his results. However, when we engage in asymmetric effects of exchange rate volatility which requires including nonlinear adjustment of volatility measures, the findings show more support to both exchange rate volatility influence and the third-country effect. Therefore, we propose that in examining exchange rate volatility effect on trade, consideration must be given to not just asymmetric effects of exchange rate volatility but also asymmetric effects of the third-country effect. We demonstrate these findings using monthly data from 54 Malaysian industries that export to the US and 63 Malaysian industries that import from the US.
A compact size coupling controllable filter with separate electric and magnetic coupling paths

This paper presents the characteristics of a miniaturized microstrip filter, which has two separate coupling paths: electric coupling path and magnetic coupling path between two resonators. Either magnetic coupling or electric coupling in two paths can be dominant in the total coupling coefficient of the inter-stage resonators with the similar configuration, but different positions of transmission zero points (ZPs). Based on the proposed filter topology, second- and fourth-order filters have been designed and fabricated for the first time. Advantages of using this type of filter are not only its low insertion loss and much more compact size, but also its controllable transmission ZPs.
Antinociceptive and anti-inflammatory effects of Caesalpinia pyramidalis in rodents

Caesalpinia pyramidalis Tul. , Fabaceae, is a plant with an anti-inflammatory activity that is used in folk medicine. To evaluate the mechanism of action of this plant, studies were performed on its antinociceptive and anti-inflammatory properties using an ethanol extract (EE) made from the inner bark. Oral treatment of mice with the EE (100, 200, and 400 mg/kg) decreased their acetic acid-induced abdominal writhes (p<0.001) and their formalin-induced paw licking in both the first and second phases (p<0.001). This treatment increased the reaction time of mice on the hot-plate test (400 mg/kg, p<0.05); however, it did not alter their performance on the Rotarod performance test. The carrageenan-induced paw edema in the rats and the leukocyte migration into the peritoneal cavity of the mice were also reduced by the EE given at a dose of 400 mg/kg (p<0.05). In addition, the EE (100-400 mg/kg, v.o.) did not alter the arterial pressure of non-anesthetized rats. In conclusion, the EE of C. pyramidalis shows antinociceptive and anti-inflammatory activities in rodents, supporting the usage of this plant to treat various inflammatory diseases for which it has traditionally been used.
Yield and Technical Quality of Scots Pine Saw Timber from Thinnings on Drained Peatlands and Mineral Soils in Finland

In this study the yield of Scots pine (Pinus sylvestris L.) timber suitable for mechanical wood processing from thinning operations in different drained peatland and mineral soil stands was determined calculatorily, using the data from field surveying. Additionally, the external quality of the trees was studied. The yield of saw timber was small in general, and its proportion of the thinning removal was modest. The largest yield was obtained when round construction timber – in addition to the normal timber assortments – was harvested. At its highest the yield of saw timber was 11 m 3 /ha (16% of thinning removal) from drained peatlands and 18 m3/ha (31% of thinning removal) from mineral soils. Also small-diameter and short logs increased the yield of saw timber from thinning stands as compared to the yield obtained harvesting only normal saw logs. In thinning stands the number of defect-free trees was small. The most frequent external defects were the deviations from the straight stem form. Despite the relatively poor quality of the trees, the main reason for the low saw timber yield was the small size of the harvested trees.
Do low survey response rates bias results? Evidence from Japan

Background: In developed countries, response rates have dropped to such low levels that many in the population field question whether the data can provide unbiased results. Objective: The paper uses three Japanese surveys conducted in the 2000s to ask whether low survey response rates bias results. A secondary objective is to bring results reported in the survey response literature to the attention of the demographic research community. Methods: Using a longitudinal survey as well as paradata from a cross-sectional survey, a variety of statistical techniques (chi square, analysis of variance (ANOVA), logistic regression, ordered probit or ordinary least squares regression (OLS), as appropriate) are used to examine response-rate bias. Results: Evidence of response-rate bias is found for the univariate distributions of some demographic characteristics, behaviors, and attitudinal items. But when examining relationships between variables in a multivariate analysis, controlling for a variety of background variables, for most dependent variables we do not find evidence of bias from low response rates. Conclusions: Our results are consistent with results reported in the econometric and survey research literatures. Low response rates need not necessarily lead to biased results. Bias is more likely to be present when examining a simple univariate distribution than when examining the relationship between variables in a multivariate model. Comments: The results have two implications. First, demographers should not presume the presence or absence of low response-rate bias; rather they should test for it in the context of a specific substantive analysis. Second, demographers should lobby data gatherers to collect as much paradata as possible so that rigorous tests for low response-rate bias are possible.
Modelling neighbourhood satisfaction of residents in high-And medium-density neighbourhoods of Lagos City, Nigeria

Using a structural equation model (SEM) and multiple linear regression (MLR), the factors influencing residents’ satisfaction in high and medium density neighbourhoods of Lagos metropolitan city, Nigeria were examined. This study takes a different approach by categorizing the factors into four domains (social environment, transportation, environmental quality, facilities). A total of 239 respondents from low-income high density and 220 from medium-income medium density neighbourhoods of the city were randomly selected. The main objective of the study was to identify the predictors of neighbourhood satisfaction among the residents of the two neighbourhoods. The results showed that a significant relationship exists between the four domains and neighbourhood satisfaction of the residents. However, the model results showed some variations in the predicting power of each of the domain. The social environment (X 2 = 7.029, p = 0.218, GFI = 0.994, AGFI = 0.982, RMSEA = 0.030, df = 5, N = 450) had more influence on residents neighbourhood satisfaction compared to other domains. Other variables found to have significantly influenced neighbourhood satisfaction in the other domains were drainage (β = 0.29), waste management (β = 0.24), street lighting, (β = 0.23) and noise pollution (β = 0.22). The finding of the study substantiates the importance of social and physical environment factors on the well-being of urban residents in developing countries.
The impact of the abolition of corporal punishment on teacher morale : 1994-2004

There is a direct correlation between (teacher) morale and (learner) discipline at sch ool. Since the scrapping of corporal punishment, a sense of despair seems to have taken over amongst teachers in South Africa. The findings of this study indicated that more than 65% of teachers, out of a sample population of 80 respondents from scho ols located in B loem fon tein in the Free State, claimed that discipline at schools had deteriorated, and that their passion for teaching and the joy they had once found in their work had been adversely affected since the decision had come in to effect. Amongst the many reasons for low morale, cited by the teachers, lack of dis cip line was clearly the most prevalent and common concern, and generally seemed to be attributed to the abolition of corporal punishment. I explore this concern and its impact on overall teacher morale.
Crystal structures and Hirshfeld surface analyses of a des-A-B-aromatic steroidal compound, and two of its derivatives, having a trans-2,3,4,5-tetrahydro-3a-methyl-7-methoxybenz[e]indane skeleton – structural comparisons with reported tetrahydrobenz[e]indene derivatives

Abstract The crystal structures and Hirshfeld surface analyses of the des-A-B-aromatic steroid derivative, (3a,9b)-1,2,3a,4,5,9b-hexahydro-7-methoxy-3a-methyl-3H-benz[e]-inden-3-one (or 5-methoxy-des-A-estra-5,7,9-triene-17-one) 1, its acetohydrazide derivative, 2, and its hydrazone derivative, 3, are reported. All three compounds crystallize in chiral space groups: compounds 1 and 2 in the orthorhombic space group P212121 each with one molecule in the asymmetric unit, and compound 3 in the monoclinic space group P21 with two similar but independent molecules, Mol A and Mol B, in the asymmetric unit. Both the five-membered and six-membered non-aromatic rings in all three compounds have envelope or near envelope shapes. In compounds 2 and 3 the N=N units have (E)-arrangements. The intermolecular interactions in crystals of compound 1 are C–H · · · O hydrogen bonds and C–H · · · π interactions, in compound 2 N–H · · · O and C–H · · · O hydrogen bonds and C–H · · · π interactions are present, while in compound 3 there are just C–H · · · π interactions. An important substructure in 1 is a sheet of molecules, composed of R66(44)${\rm{R}}_6^6(44)$ rings, formed from C–H · · · O(methoxy) and C–H · · · O(carbonyl) hydrogen bonds, the molecules of which form columns linked via the B and D rings, i.e. in a head-to-tail fashion. Compound 2 is an acylhydrazonyl compound, in which the two independent molecules are linked into asymmetric dimers via strong classical N–H · · · O hydrogen bonds, with the formation of R22(8)${\rm{R}}_2^2(8)$ rings. In both 1 and 2, further intermolecular interactions result in 3-dimensional structures, while compound 3 has a 1-dimensional structure arising from C–H · · · O interactions generating spiral chains. The results have been compared with existing data.
Framing Gender Justice

Abstract This study examines the media coverage of the #metoo movement in neighbouring countries Denmark and Sweden. A comparative content analysis shows differences in genres, sources and themes across the two samples. Further, the analysis shows that the coverage predominantly positioned #metoo within an individual action frame portraying sexual assault as a personal rather than societal problem in both countries. However, the individual action frame and a delegitimising frame focused on critique of #metoo were more prevalent in the Danish coverage. A framing analysis revealed four different news frames in the coverage: #metoo as (1) an online campaign connecting networked individuals, (2) part of a broader and long-standing social movement for gender justice, (3) an unnecessary campaign fuelled by cultures of political correctness and, finally, (4) a witch hunt and “kangaroo court”. Finally, we discuss and relate these findings to the political and cultural contexts of the two countries and their different historical trajectories for the institutionalisation of feminism and implementation of gender equality policies.
The Recillas's conjecture on Szegö kernels associated to Harish-Chandra Modules

The solution of the field equations that involves non-flat differential operators (curved case) can be obtained as the extensions Φ+Szego operators in G/K with G, a non-compact Lie group with K, compact. This could be equivalent in the context of the Harish-Chandra modules category to the obtaining of extensions in certain sense (Cousin complexes of sheaves of differential operators to their classification) of Verma modules as classifying spaces of these differential operators and their corresponding integrals through of geometrical integral transforms.
Correlates of Distinct Cognitive Impairments in Parkinson ’ s Disease

The spectrum of cognitive symptoms in Parkinson’s disease (PD) can span various domains, including executive function, language, attention, memory, and visuospatial skills. These symptoms may be attributable to the degradation of projection fibers associated with the underlying neurodegenerative process. The primary purpose of this study is to find microstructural correlates of impairments across these cognitive domains in PD using diffusion tensor imaging (DTI). Sixteen patients with PD with comprehensive neuropsychological evaluation and DTI data were retrospectively studied. Fractional anisotropy (FA) and mean diffusivity (MD) were assessed using regions-of-interest (ROI) analysis and confirmed with a voxel-based approach. Executive function directly correlated with FA and inversely correlated with MD in mostly frontal white matter tracts, especially the anterior limb of the internal capsule and genu of the corpus callosum. Likewise, language and attentional performance demonstrated correlations with DTI parameters in the frontal regions, but the attention domain additionally recruited regions widespread throughout the brain, with the most significant correlation identified in cingulate gyrus (cingulum). Lastly, memory impairment mainly involved MD alterations within the fornix. No significant correlations were found between visuospatial skills and DTI measures. Despite some overlap, unique patterns of white matter diffusivity underlie impairments in distinct cognitive domains in patients with PD. DTI combined with neurocognitive tests may be a valuable biomarker for identifying cognitive impairments in PD. Hum Brain Mapp 35:1325–1333, 2014. VC 2013 Wiley Periodicals, Inc.