Miracle-dz/UniFAR-FTUs huggingface dataset:
Effects of pharmacist interventions on heart failure outcomes: A systematic review and meta‐analysis

Heart failure (HF) patients tend to have multiple comorbidities resulting in complex therapy regimens and medication adherence issues. Nevertheless, the evidence of pharmacists' contributions to improving clinical outcomes in HF is limited. To assess the impact of pharmacist intervention on all‐cause hospitalization, mortality, and quality of life (QoL) in HF) patients. A systematic search of PubMed, Embase, the Cochrane Central Register of Controlled Trials, Scopus, and CINAHL was performed up to April 30, 2020. Randomized controlled trials (RCTs) evaluating pharmacist interventions compared with usual care in adult HF patients were selected. Data were extracted independently by two authors. Random effects meta‐analysis models were used to pool treatment effects and confidence intervals (CIs). Twenty‐nine trials identified 6965 predominantly HF with reduced ejection fraction (HFrEF) patients. The average age was 72.0 years (interquartile range [IQR] 66.0‐76.0) and 48% were men (IQR 40.0%‐68.0%). The majority were New York Heart Association (NYHA) Functional class (FC) II‐III with median left ventricular ejection fraction (LVEF) of 38.5% (IQR 34.5%‐49.5%). Pharmacist interventions were associated with a significant reduction of all‐cause mortality (risk ratio [RR] 0.72; 95% CI 0.58‐0.89; P = 0.003) and all‐cause hospitalizations (RR 0.87; 95% CI 0.77‐0.99; P = 0.041). A significant increase in the 36‐item Short form Health survey (SF‐36) on role physical (Mean deviation [MD], 8.5; 95% CI, 1.00 to 16.01, P = 0.026) and mental health (MD, 7.49; 95% CI, 3.88 to 11.10, P < 0.001) were observed. In addition, a significant improvement in Minnesota Living with Heart Failure Questionnaire score was observed (MD ‐3.55; 95% CI ‐6.28 to −0.82; P = 0.01). Pharmacist interventions in patients with HF significantly reduced all‐cause mortality and hospitalizations and improved QoL. Integration of a pharmacist into a HF care team or care pathway should be strongly considered as an important element of a multidisciplinary team.
An empirical study of regression testing techniques

Regression testing is a testing process for established software and developed ones. Adding features to the software should not cause errors in the previous software version. There are several methods for implementing regression testing. The most straightforward is to do retest-all, but this technique is costly and protracted because it has to execute all test cases in the test suite. This situation is the nature of regression testing research, i.e. determining how to execute only a few test cases to shorten the time, and the faults can be found as much as possible. Recently there are various algorithms for regression testing process. This paper explains an empirical study of several regression testing methods. In the empirical evaluation, we used open-source SUTs, and several are implemented ourselves. On the other side, we utilize an MTS tool from the software artefact repository (SIR) and other open-source tools to automatic testing execution. The empirical study shows that each technique has a specific characteristic, and also has effectiveness significantly to reduce execution time testing process. So that in the regression testing implementation, it is crucial to determining the techniques considering each of them has consequences.
Residual Tau-Fluvalinate in Honey Bee Colonies Is Coupled with Evidence for Selection for Varroa destructor Resistance to Pyrethroids

Simple Summary Varroa destructor is one of the most prevalent honey bee (Apis mellifera) pathogens worldwide. Nowadays, the main method to control this parasite involves the application of different acaricidal treatments, among which the pyrethroid tau-fluvalinate is one of the most widely used. However, the intensive and repetitive application of these chemicals generates a selective pressure that, when maintained over time, contributes to the emergence of resistant mites in the honey bee colonies. Here we analysed the presence of residual tau-fluvalinate and the patterns of genetic resistance to this acaricide in Varroa mites collected from tau-fluvalinate untreated honey bee colonies. Our results show the widespread and persistent pyrethroid contamination of beeswax and beebread in the hives, along with an excess of pyrethroid-resistant genotypes and an overall increase in the frequency of the pyrethroid-resistant allele in the mite population over time. Persistent contamination of the hives likely compromises the efficacy of tau-fluvalinate treatments and, therefore, may have serious long-term consequences for the control of varroosis. Abstract Varroa destructor is considered one of the most devastating parasites of the honey bee, Apis mellifera, and a major problem for the beekeeping industry. Currently, the main method to control Varroa mites is the application of drugs that contain different acaricides as active ingredients. The pyrethroid tau-fluvalinate is one of the acaricides most widely used in beekeeping due to its efficacy and low toxicity to bees. However, the intensive and repetitive application of this compound produces a selective pressure that, when maintained over time, contributes to the emergence of resistant mites in the honey bee colonies, compromising the acaricidal treatments efficacy. Here we studied the presence of tau-fluvalinate residues in hives and the evolution of genetic resistance to this acaricide in Varroa mites from honey bee colonies that received no pyrethroid treatment in the previous four years. Our data revealed the widespread and persistent tau-fluvalinate contamination of beeswax and beebread in hives, an overall increase of the pyrethroid resistance allele frequency and a generalized excess of resistant mites relative to Hardy–Weinberg equilibrium expectations. These results suggest that tau-fluvalinate contamination in the hives may seriously compromise the efficacy of pyrethroid-based mite control methods.
Uncertainty analysis in parameter regionalization for streamflow prediction in ungauged semi-arid catchments

ABSTRACT Predicting in ungauged basins (PUB) depends on the modelling uncertainties in the donor catchments (DCs). However, PUB is normally limited to a unique outcome, which may be quite uncertain, mainly in semi-arid basins where streamflow variability is high. Our goal is to assess the uncertainty in the parameter regionalization for streamflow prediction in semi-arid ungauged basins (UB). We used Differential Evolution Adaptive Metropolis (DREAM) for a parameter calibration that considers its intrinsic uncertainty. A basin similarity regionalization was performed to transfer the parameters to UB, considering one, three and five DCs. Leave-one-out cross-validation was applied for 28 gauged catchments. Regionalization performance had average Nash-Sutcliffe efficiency above 0.50. The approach considering one DC performed better than the others. The model of a poorly monitored catchment performed better using the transferred parameters from long-recorded, similar catchments than using those calibrated in the catchment itself. The developed regionalization may be a relevant tool for water management in drylands.
A Faster Constant-time Algorithm of CSIDH keeping Two Torsion Points

At ASIACRYPT 2018, Castryck, Lange, Martindale, Panny and Renes proposed CSIDH, which is a key-exchange protocol based on isogenies between elliptic curves, and a candidate for post-quantum cryptography. However, the implementation by Castryck et al. is not constant-time. Specifically, a part of the secret key could be recovered by the side-channel Attacks. Recently, Meyer, Campos and Reith proposed a constant-time implementation of CSIDH by introducing dummy isogenies and taking secret exponents only from intervals of non-negative integers. Their non-negative intervals make the calculation cost of their implementation of CSIDH twice that of the worst case of the standard (variable-time) implementation of CSIDH. In this paper, we propose a more efficient constant-time algorithm that takes secret exponents from intervals symmetric with respect to the zero. For using these intervals, we need to keep two torsion points in an elliptic curve and calculation for these points. We evaluate the costs of our implementation and that of Meyer et al. in terms of the number of operations on a finite prime field. Our evaluation shows that our constant-time implementation of CSIDH reduces the calculation cost by 28.23% compared with the implementation by Mayer et al. We also implemented our algorithm by extending the implementation in C of Meyer et al. (originally from Castryck et al.). Then our implementation achieved 172.4 million clock cycles, which is about 27.35% faster than that of Meyer et al. and confirms the above reduction ratio in our cost evaluation.
An Analysis of Illocutionary Act in Incredible 2 Movie

The objective of this research is to analyze the types of illocutionary act in the Incredible 2 movie and to interpret the dominant types of illocutionary act. Searle’s theory are used by the researchers to answer the formulated research questions. This research is a qualitative research applying content or document analysis. The subject of this research is a movie entitled Incredible 2 movie The data were some scene including the illocutionary act in Incredible 2 movie. To collecting the data, the researchers downloading the movie from google, watching the film “Incredible 2” for several time, then searching for the script of the movie in the internet, watching the movie while reading the script, finding some sentences that are considered to have illocutionary act needed for the analysis and found the dominant types of illocutionary act, After collected the data, the researchers analyze the data based on some steps, classifying the illocutionary act, finding the dominant types of the illocutionary act, The findings of the research are as follows: in Incredible Movie, Searle’s theory there are 5 types of illocutionary act are found: From those types, in movie Incredible found the types of illocutionary act as follows : directives consist of 8 data (32%), assertive consist of 7 data (28%), expressive consist of 7 data (28%), commisive consist of 2 data (8%) and declaration sonsist of 1 data(4%).
Research Status and Challenges of Data-Driven Construction Project Management in the Big Data Context

The construction industry is facing a data tsunami, while emerging information technologies (IT) show great potential for the effective processing of these data or information. However, a comprehensive review for technological change, the resulting process, and organizational changes in the Big Data context, especially from the angle of whole lifecycle of construction project, is lacking. To fill the void, related works published in the databases of Web of Science, Science Direct, and American Society of Civil Engineers library are systematically reviewed. The general trend in emerging IT application in terms of construction project management (CPM) phases, technology and application, and research topics are revealed. Following this analysis, the particularized proposals in relation to each of the main topics within CPM is discussed. Furthermore, according to the advances and limitations of the current literature, corresponding future agendas such as the implementation of comprehensive data-driven CPM scenario are proposed to bridge the gaps between theoretical research and practical demands.
‘Without uniform I am a community member, uncle, brother, granddad’: Community policing in Australia’s Torres Strait Region

As a palpable legacy of violent colonialism, Aboriginal and Torres Strait Islander (‘Indigenous’) Australians are the most incarcerated peoples in the world. Community policing, which hinges on the development of trusting community–police partnerships, is frequently proposed as a means of reducing this over-representation, but approaches vary and produce divergent outcomes. This article draws on interview data to explore policing in Australia’s Torres Strait Region – a remote archipelago situated off the northern tip of Queensland. A strong commitment to community and hybridised policing approaches likely provide a partial explanation for relatively low crime in the region. However, under-reporting of some offences (e.g. domestic violence) suggests a possible need to overlay alternative approaches that improve access to justice for all victims, especially women. Overall, the Torres Strait Region experience holds possible lessons for policing in Australia’s other remote Indigenous communities, again demonstrating that decolonisation is a critical starting point for addressing over-representation.
Comparative phylogeographic analysis suggests a shared history among eastern North American boreal forest birds

ABSTRACT Phylogeographic structure within high-latitude North American birds is likely shaped by a history of isolation in refugia during Pleistocene glaciations. Previous studies of individual species have come to diverse conclusions regarding the number and location of likely refugia, but no studies have explicitly tested for biogeographic concordance in a comparative phylogeographic framework. Here we use a hierarchical approximate Bayesian computation analysis of mitochondrial DNA sequences from 653 individuals of 6 bird species that are currently co-distributed in the boreal forest of North America to test for biogeographic congruence. We find support for congruent phylogeographic patterns across species, with shallow divergence dating to the Holocene within each species. Combining genetic results with paleodistribution modeling, we propose that these species shared a single Pleistocene refugium south of the ice sheets in eastern North America. Additionally, we assess modern geographic genetic structure within species, focusing on Newfoundland and disjunct high-elevation populations at the southern periphery of ranges. We find evidence for a “periphery effect” in some species with significant genetic structure among peripheral populations and between peripheral and central populations. Our results suggest that reduced gene flow among peripheral populations, rather than discordant biogeographic histories, can explain the small differences in genetic structure and levels of genetic diversity among co-distributed boreal forest birds. LAY SUMMARY Six currently co-distributed eastern boreal birds share a recent phylogeographic history, expanding from a single common Pleistocene glacial refugia, likely located south of the ice sheets in eastern North America. This research helps us understand whether species within communities respond in similar ways to large-scale geologic and climatic events. Differences in genetic diversity among boreal species are most likely due to modern processes such as isolation in peripheral populations, as opposed to discordant histories. We found significant isolating effects of Newfound and southern periphery populations in Northeastern North America, though this appeared to vary across species.
Bipolar Bidirectional DC-DC Converter for Bi-Polar DC Micro-grids with Energy Storage Systems

ABSTRACT This paper proposes a non-isolated bipolar bidirectional DC–DC converter with an interleaved switched capacitor for bipolar DC micro-grids suitable for both low-power and high-power applications to achieve high-voltage gain. Interleaved structure on the low-voltage side is proposed to realise current sharing to reduce current ripple and switched capacitor topology on high-voltage side to achieve high-voltage gain. Soft switching, high efficiency and simple control make this converter employable in several applications such as electric vehicles, energy storage systems, etc. Simulation and hardware results are presented to highlight the merits of the proposed converter topology.
Grid-Forming Control for Solar PV Systems With Power Reserves

This paper presents a grid-forming control (GFC) scheme for two-stage photovoltaic (PV) systems that maintains power reserves by operating below the maximum power point (MPP). The PV plant in GFC mode behaves like a voltage source that supports the grid during disturbances in full or limited grid-forming mode as per the reserve availability. This is a model-free method that avoids the estimation of MPP power in real-time commonly done in the literature, which makes it simpler and more reliable. The proposed control also features an enhanced current limitation scheme that guarantees containment of the current overshoots during faults, which is not trivial in voltage-sourced GFC inverters. A thorough investigation is done, exploring various generation mixtures of synchronous machines (SM), GFC and grid-following (GFL) inverters, and all common disturbances, e.g., load change, faults and irradiance transients. The results show very favorable dynamic performance by the GFC inverters, far superior to GFL inverters and directly comparable to SMs. It is found that replacing SMs with GFC inverters may improve the frequency profile and terminal voltage during disturbances, despite losing out in the mechanical inertia and the strict inverter overcurrent limits.
The 1st International Project Competition for Structural Health Monitoring (IPC-SHM, 2020): A summary and benchmark problem

To promote the development of structural health monitoring around the world, the 1st International Project Competition for Structural Health Monitoring (IPC-SHM, 2020) was initiated and organized in 2020 by the Asia-Pacific Network of Centers for Research in Smart Structures Technology, Harbin Institute of Technology, the University of Illinois at Urbana-Champaign, and four leading companies in the application of structural health monitoring technology. The goal of this competition was to attract more young scholars to engage in the study of structural health monitoring, encouraging them to provide creative and effective solutions for full-scale applications. Recognizing the recent advent and importance of artificial intelligence in structural health monitoring, three competition projects were set up with the data from full-scale bridges: (1) image-based identification of fatigue cracks in bridge girders, (2) data anomaly detection for structural health monitoring, and (3) condition assessment of stay cables using cable tension data. Three corresponding data sets were released at http://www.schm. org.cn and http://sstl.cee. illinois.edu/ipc-shm2020. Participants were required to be full-time undergraduate students, M.S. students, Ph.D. students, or young scholars within 3 years after obtaining their Ph.D. Both individual and teams (each team had no more than five individuals) could compete. Submissions for the competition included a 10- to 15-page technical paper, a 10-min presentation video with PowerPoint slides, and commented code. The organizing committee then conducted the validation, review, and evaluation. A total of 330 participants in 112 teams from 70 universities and institutions in 12 countries registered for the competition, resulting in 75 papers from 56 teams from 57 different affiliations finally being submitted. Of those submitted, 31, 30, and 14 papers were for Projects 1, 2, and 3, respectively. After completion of the review by the organization committee and awards committee, the top 10, 10, and 5 teams were selected as the prize winners for the three competition projects.
Fault Analysis and Non-Redundant Fault Tolerance in 3-Level Double Conversion UPS Systems Using Finite-Control-Set Model Predictive Control

Fault-tolerance is critical in power electronics, especially in Uninterruptible Power Supplies, given their role in protecting critical loads. Hence, it is crucial to develop fault-tolerant techniques to improve the resilience of these systems. This paper proposes a non-redundant fault-tolerant double conversion uninterruptible power supply based on 3-level converters. The proposed solution can correct open-circuit faults in all semiconductors (IGBTs and diodes) of all converters of the system (including the DC-DC converter), ensuring full-rated post-fault operation. This technique leverages the versatility of Finite-Control-Set Model Predictive Control to implement highly specific fault correction. This type of control enables a conditional exclusion of the switching states affected by each fault, allowing the converter to avoid these states when the fault compromises their output but still use them in all other conditions. Three main types of corrective actions are used: predictive controller adaptations, hardware reconfiguration, and DC bus voltage adjustment. However, highly differentiated corrective actions are taken depending on the fault type and location, maximizing post-fault performance in each case. Faults can be corrected simultaneously in all converters, as well as some combinations of multiple faults in the same converter. Experimental results are presented demonstrating the performance of the proposed solution.
Circularly polarized high-power antenna with higher-order mode excitation

Abstract A circularly polarized high-power antenna with higher-order mode excitation (TM01) is presented in this paper. The proposed structure consists of metal plates placed on the conical horn antenna's aperture for achieving TM01 to circular polarized TE11 mode conversion at the output. The structure is simulated on CST Microwave Studio. The designed antenna exhibits high gain and a directive radiation pattern. The axial ratio of the proposed structure is below 3 dB. The simulated and measured reflection coefficient for TM01 mode excitation is below −10 dB over a frequency range of 2.95–3.13 GHz. The structure is purely metallic, and the calculated high-power microwave (HPM) capability is up to the MW level. The proposed antenna is helpful for portable HPM systems.
Differences in Adolescents With Down Syndrome and Asperger in a Social Skills Training Program

Background/Objective: Researchers have traditionally reported that individuals with Down syndrome possess a strength in their social development, yet the opposite occurs with Asperger’s syndrome. Based on this premise, we sought to assess effectiveness of the social skills training program. Method: Thirty adolescents aged 11 to 14 years with Down syndrome and Asperger’s syndrome participated in the study. Results: Significant differences between both groups were detected in the posttreatment measures and a connection was found between adolescents’ learning potential and the benefits gained. Conclusions: The training program is effective at improving the social skills under evaluation in adolescents with Down syndrome; however, this benefit is greater among adolescents with Asperger’s syndrome.
Virus-like particles with tunable morphology derived from amphiphilic polyplexes

ABSTRACT Virus-like particles are a significant class of biomaterials composed of coat polymers and DNA that assemble into different shapes with a variety of sizes from tens to hundreds of nanometers. In this work, a novel system of virus-like hierarchical nanostructures has been developed by the combination of poly(ethylene glycol)-poly(L-lysine) block copolymers with the poly(benzyl ether) dendron-DNA hybrids. Because of the unique topological structure of polyelectrolytes, the dimension of assemblies could be switched from 1D nanorods to 2D nanosheets to 3D vesicles via varying the molar ratio of two components. Morphologies of the vesicles were characterized by transmission electron microscopy.