Miracle-dz/UniFAR-FTUs huggingface dataset:
Incidence and risk factors of workplace violence on psychiatric staff.

BACKGROUND A study by Hesketh et al. found that 20% of psychiatric nurses were physically assaulted, 43% were threatened with physical assault, and 55% were verbally assaulted at least once during the equivalent of a single work week. From 2005 through 2009, the U.S. Department of Justice reported that mental health occupations had the second highest average annual rate of workplace violence, 21 violent crimes per 1,000 employed persons aged 16 or older. OBJECTIVE An evaluation of risk factors associated with patient aggression towards nursing staff at eight locked psychiatric units. PARTICIPANTS Two-hundred eighty-four nurses in eight acute locked psychiatric units of the Veterans Health Administration throughout the United States between September 2007 and September 2010. METHODS Rates were calculated by dividing the number of incidents by the total number of hours worked by all nurses, then multiplying by 40 (units of incidents per nurse per 40-hour work week). Risk factors associated with these rates were analyzed using generalized estimating equations with a Poisson model. RESULTS Combining the data across all hospitals and weeks, the overall rate was 0.60 for verbal aggression incidents and 0.19 for physical aggression, per nurse per week. For physical incidents, the evening shift (3 pm - 11 pm) demonstrated a significantly higher rate of aggression than the day shift (7 am - 3 pm). Weeks that had a case-mix with a higher percentage of patients with personality disorders were significantly associated with a higher risk of verbal and physical aggression. CONCLUSION Healthcare workers in psychiatric settings are at high risk for aggression from patients.
An automatic ECG processing algorithm to identify patients prone to paroxysmal atrial fibrillation

An algorithm to identify patients prone to paroxysmal atrial fibrillation (PAF) has been developed and evaluated using the PAF Prediction Challenge Database. The procedure is based on conventional electrocardiogram (ECG) signal pre-processing techniques for beat detection and classification, a correlation-based assessment of the P-wave morphology of both regular and premature heart beats of supraventricular origin, and a statistical test to calculate the PAF predictive parameter, i.e. the probability that a certain degree of P-wave variability is associated with potential triggers for PAF. This probability, finally, is used to differentiate between patients with and without PAF (screening) and to find out which of the two recordings of each patient immediately precedes the onset of PAF (prediction), respectively. The obtained diagnostic accuracies of 82% and 84%, respectively, indicate that this concept may be useful in terms of clinical PAF risk stratification.
Educational community stakeholders' perspectives about teachers' responsibilities for mental health promotion in Maltese schools

The studies reported in this paper were supported by grants from the European Union FP7 Marie Curie International Research Staff Exchange Scheme, the Australian Academy of Science, the Faculty of Education, Humanities and Law at Flinders University and the European Centre for Educational Resilience and Socio-Emotional Health at the University of Malta.
Risk Stratification in Patients Undergoing Percutaneous Coronary Revascularization

Aims: The SYNTAXTM score has been designed to better anticipate the risks of percutaneous or surgical revascularisation, taking into account the functional impact of the coronary circulation with all its anatomic components including the presence of bifurcations, total occlusions, thrombus, calcification, and small vessels. The purpose of this paper is to describe the baseline assessment of the SYNTAXTM score in the Syntax randomised trial, the corelab reproducibility, the potential difference in score assessment between the investigator and the corelab, and to ascertain the impact on one-year outcome after either percutaneous coronary intervention (PCI) or coronary artery bypass surgery (CABG) in patients with complex coronary artery disease. Methods and results: To assess the reliability of SyntaxTM scoring, 100 diagnostic angiograms from the Syntax trial were randomly selected and assessed independently by two observers. Intra-observer variability was assessed by analysing 91 sets of angiograms after an interval of at least eight weeks by one of the observers. Clinical outcomes in the randomised cohort of the Syntax trial up to one year are presented with stratification by tertile group of the SYNTAXTM score. The weighted kappa value for the inter-observer reproducibility on the global score was 0.45, while the intra-observer weighted kappa value was 0.59. The SYNTAXTM score as calculated by investigators consistently underscored the corelab score by 3.4 points. When the Syntax randomised cohort was stratified by tertiles of the SYNTAXTM score, there were similar or nonsignificantly different MACCE rates in those with low or intermediate scores; however in the top tertile the MACCE rate was greater in those receiving PCI compared to CABG. Conclusions: The SYNTAXTM score is a visual coronary score with an acceptable corelab reproducibility that has an impact on the one-year outcome of those having PCI, whereas it has no effect on the one-year outcome following surgical revascularisation. The SYNTAXTM score tool is likely to be useful in a wide range of patients with complex coronary disease.
Biomarkers to advance drug development for Alzheimer’s disease

There is a sense of excitement and anticipation that drugs based on the β-amyloid hypothesis of Alzheimer’s disease (AD) may significantly reduce progression of the disease. However, without appropriate biomarkers, potentially effective drugs may actually fail to demonstrate efficacy owing to difficulties in choosing a proper dose and difficulty in detecting improved clinical outcomes in short trials. Both hypothesis- and discovery-based approaches, including high-throughput proteomic profiling, should be applied for discovery of biomarkers to better understand the action of novel therapies on their targets and on the molecular pathology of the disease. It is also imperative to identify antecedent markers, without which, patients with AD will be prescribed drugs that may prolong a life of slowly progressing dementia. Where we look for novel AD biomarkers and how we discover them is the subject of this perspective.
The Physiology of the Newborn Infant

It is of interest to review the trend in books about the newborn and perinatal areas. Not long ago there were only three major texts: The Physiology of the Newborn Infant , by Dr Clement A. Smith; The Management of the Newborn , by Dr Arthur Parmalee; and The Premature Infant by Dr Beryl Corner. Later Schaffer added Diseases of the Newborn . These texts had in common one major characteristic: each was written by a single author. Today we are in the midst of a veritable avalanche of multi-authored books on the newborn and perinatal medicine. Multi-authored books seem to be developed along two lines. One is as a standard textbook in which the editor (or editors) lays out a plan and recruits a number of authors who write chapters that may overlap or have no interrelationship and who write in a variety of styles. Frequently, they are not objective and some
Obesity indicators and cardiometabolic status in 4-y-old children.

BACKGROUND In adults and adolescents, obesity is positively associated with cardiovascular disease risk factors; however, evidence in preschool children is scarce. OBJECTIVE The objective was to assess the relations between obesity indicators and cardiometabolic risk factors in 324 Chilean children 4 y of age. DESIGN We collected anthropometric measurements and calculated general indicators of obesity [weight, body mass index (BMI), sum of 4 skinfold thicknesses, percentage fat, and body fat index] and central obesity (waist circumference, waist-to-hip ratio, waist-to-height ratio, and truncal fatness based on skinfold thickness). We measured blood sample concentrations of C-reactive protein, interleukin-6, homeostasis model assessment of insulin resistance, triglycerides, and total, LDL, and HDL cholesterol. We used correlation and multiple linear regression analyses. RESULTS The prevalence of obesity (BMI-for-age z score >2, World Health Organization 2006), central obesity (> or = 90th percentile, third National Health and Nutrition Examination Survey), and lipid disorders was high (13%, 11%, and > or = 20%, respectively), and 70% of the children had at least one cardiometabolic risk factor. Most correlations between obesity and central obesity indicators were moderate to strong (0.40 < r < 0.96). Obesity was positively but weakly associated with C-reactive protein in both sexes and with homeostasis model assessment of insulin resistance only in girls (all r < 0.3, P < 0.05). Obesity indicators were unrelated to interleukin-6 and lipid concentrations (P > 0.05). Overall, obesity indicators explained, at most, 8% of the variability in cardiometabolic risk factors. CONCLUSIONS Obesity and central obesity were common, and most of the children had at least one cardiometabolic risk factor, particularly lipid disorders. Obesity and central obesity indicators were highly intercorrelated and, overall, were weakly related to cardiometabolic status. At this age, body mass index and waist circumference were poor predictors of cardiometabolic status.
A kinectV2-based 2D Indoor SLAM Method

SLAM is the key to realize the autonomous movement of the robot. 2D laser scanner performs well in indoor SLAM. However, with high resolution, wide viewing angle and low cost, kinectV2 has become a new platform for SLAM research. In this paper, we propose a 2D indoor SLAM method to replace 2D laser scanner. The real-time kinectV2 depth image information is obtained and converted into 2D laser data, effectively replacing the 2D laser scanner. The whole experiment is based on the robot operating system (ROS), using Hector SLAM algorithm for 2D SLAM. The results show that the proposed method is a reliable and effective 2D SLAM method, which achieves the expected results.
Dietary Patterns and Non Communicable Disease Among Iranian Women: A Systematic Review

Context: Diet is an important component of life and plays a key role in the prevention or development of non-communicable diseases. The aim of this systematic review was to determine different dietary patterns and their association with non-communicable diseases in Iranian women. Evidence Acquisition: Sources of Information: an electronic literature search was conducted on websites such as Pubmed, Science direct, Google scholar, Sid, and Iranmedex to identify original human studies, published in English and Persian up to August 2013 that included keywords or phrases relevant to the aim of this study. Results: Studies were classified into eight groups according to their objectives and outcomes, including the relationship between dietary patterns and aspects such as bone mineral density, metabolic syndrome, obesity, cardiovascular disease, cancer, markers of inflammation, hypertension, coagulation abnormalities, life style and factor analysis. Compared to healthy dietary patterns, the western and Iranian patterns were positively associated with conditions related to non-communicable diseases. The dietary approach to stop hypertension (DASH) is rich in fruits, vegetables, whole grains, low-fat dairy products, and is low in saturated fat, total fat, cholesterol, refined grains, and sweets. This diet is associated with greater high-density lipoprotein (HDL) cholesterol and lower body weight, waist circumference, fasting blood glucose, low-density lipoprotein (LDL) cholesterol and systolic and diastolic blood pressures. Conclusions: Adherence to a healthy dietary pattern is expected to secure a protective effect against non-communicable disease.
Cuestionario de frecuencia de consumo de alimentos para estimación de ingestión de folato en México

OBJETIVO: Evaluar la reproducibilidad y validez de la ingestion de folato (IF),estimada a partir de un cuestionario de frecuencia de consumo (CFC), considerando el factor de retencion (FR) correspondiente al metodo de preparacion empleado. MATERIAL Y METODOS: Al inicio del estudio se entrevisto a 497 adultos sanos; un ano despues se realizo una segunda entrevista a una muestra de 100 individuos seleccionados aleatoriamente,quenohubieran modificadosudietadurante el ano previo; adicionalmente, para evaluar la validez de la IF, mediante radioinmunoensayo,se determinaron los niveles de folato serico (FS). RESULTADOS: La reproducibilidad de la IF fue de 0.36 y 0.34 para el folato sin y con FR,respectivamente. Se observo una correlacion significativa entre la IF y el FS de 0.18 con FR y 0.21 sin FR (p<0.05, respectivamente). CONCLUSIONES: Incorporar el FR en las estimaciones de la IF no mejora la reproducibilidad ni la validez de las mismas.
Does Change in Gait while Counting Backward Predict the Occurrence of a First Fall in Older Adults?

Background: Dual-task-based assessment tests failed to establish a dependable relationship between dual-task-related gait changes and the risk of falls in the elderly. Objective: The aim of this study was to examine whether changes in gait while counting backward could be associated with the occurrence of a first fall among older adults. Methods: Walking while counting backward was investigated prospectively in a cohort of 187 older adults living independently in senior housing facilities. During enrollment, walking time, number of steps, and frequency of lateral line stepping-over and stops were measured while walking only and while walking with backward counting aloud. Information on the incident falls during the follow-up year was collected monthly. Results: Walking time and the number of steps increased significantly under the dual-task condition compared to the single-task condition among fallers and non-fallers (p < 0.001). Compared to non-fallers, fallers had significantly lower scores in the Mini-Mental State Examination (p = 0.029) and higher scores in the 15-item Geriatric Depression Scale (p = 0.003) and Timed Up & Go Test (p = 0.006) and increased walking time under both walking conditions (p = 0.030 for single-task condition and p = 0.007 for dual-task condition). After adjusting for these variables, depressive symptoms (adjusted OR = 2.6 with p = 0.041 and adjusted OR = 2.5 with p = 0.045 when walking time while walking only and walking with backward counting is considered, respectively) and walking time while walking only (OR = 2.3 with p = 0.032) were significantly associated with falls. Conclusion: Dual-task-related gait changes were poorly associated with the occurrence of a first fall and provided no additional predictive value compared to gait performance under a single task, suggesting that changes in basic clinical gait parameters while counting backward are unsuccessful to predict the first fall among older adults.
Defining the limits of athlete's heart: implications for screening in diverse populations.

Whereas consensus exists on the need for preparticipation examinations in young athletes, the best approach to such screening is debated. Preparticipation examinations help athletes avoid musculoskeletal injury and repeated concussion, but most attention is focused, understandably, on the avoidance of sudden cardiac death. To this end, in the United States, a brief clinical examination and questionnaire focusing on symptoms and family history (Table 1) are recommended by the 36th Bethesda Conference guidelines.1–3 Meanwhile, the International Olympic Committee and the European Society of Cardiology, drawing from the 25-year Italian experience,4 have recommended the inclusion of a 12-lead ECG in the preparticipation examination of young athletes.5–7 Debate surrounding these different approaches focuses on cost, effectiveness, differences in cause distribution in different countries, and the consequences of false-positive ECG findings.3,8 In relation to the last, whereas cost-effectiveness analysis can account for financial implications of secondary testing, the psychological burden is harder to quantify. Indeed, even between studies, the percentage of athletes screened with ECG who are deemed to require follow-up varies widely. In the Italian experience, 8% of athletes qualified for secondary screening,4 whereas an earlier US study with 501 athletes suggested a secondary screening rate as high as 15%. 9 In the largest study to date, Pelliccia et al reported that 4.8% of 32 642 athletes exhibited findings classified as “distinctly abnormal” on ECG.10 In fact, others have reported a follow-up rate as low as 1.5% with adapted ECG criteria.11 In this context, the consistent and accurate definition of “normal” becomes paramount. View this table: Table 1. Medical History * Article see p 1078 It is against this background that we view the most recent data from Rawlins and coauthors in this issue of Circulation . 12 These authors compared 240 nationally ranked black female athletes with 200 …
Paths to tobacco abstinence: A repeated-measures latent class analysis.

OBJECTIVE Knowledge of smoking change processes may be enhanced by identifying pathways to stable abstinence. We sought to identify latent classes of smokers based on their day-to-day smoking status in the first weeks of a cessation attempt. We examined treatment effects on class membership and compared classes on baseline individual differences and 6-month abstinence rates. METHOD In this secondary analysis of a double-blind randomized placebo-controlled clinical trial (N = 1,433) of 5 smoking cessation pharmacotherapies (nicotine patch, nicotine lozenge, bupropion SR, patch and lozenge, or bupropion SR and lozenge), we conducted repeated-measures latent class analysis of daily smoking status (any smoking vs. none) for the first 27 days of a quit attempt. Treatment and covariate relations with latent class membership were examined. Distal outcome analysis compared confirmed 6-month abstinence rates among the latent classes. RESULTS A 5-class solution was selected. Three-quarters of smokers were in stable smoking or abstinent classes, but 25% were in classes with unstable abstinence probabilities over time. Active treatment (compared to placebo), and particularly the patch and lozenge combination, promoted early quitting. Latent classes differed in 6-month abstinence rates and on several baseline variables, including nicotine dependence, quitting history, self-efficacy, sleep disturbance, and minority status. CONCLUSIONS Repeated-measures latent class analysis identified latent classes of smoking change patterns affected by treatment, related to known risk factors, and predictive of distal outcomes. Tracking behavior early in a change attempt may identify prognostic patterns of change and facilitate adaptive treatment planning.
Mathematical Epidemiology of Infectious Diseases: Model Building, Analysis and Interpretation

Provides systematic coverage of the mathematical theory of modelling epidemics in populations, with a clear and coherent discussion of the issues, concepts and phenomena. Mathematical modelling of epidemics is a vast and important area of study and this book helps the reader to translate, model, analyse and interpret, with numerous applications, examples and exercises to aid understanding.
Language-universal Sensory Deficits in Developmental Dyslexia: English, Spanish, and Chinese

Studies in sensory neuroscience reveal the critical importance of accurate sensory perception for cognitive development. There is considerable debate concerning the possible sensory correlates of phonological processing, the primary cognitive risk factor for developmental dyslexia. Across languages, children with dyslexia have a specific difficulty with the neural representation of the phonological structure of speech. The identification of a robust sensory marker of phonological difficulties would enable early identification of risk for developmental dyslexia and early targeted intervention. Here, we explore whether phonological processing difficulties are associated with difficulties in processing acoustic cues to speech rhythm. Speech rhythm is used across languages by infants to segment the speech stream into words and syllables. Early difficulties in perceiving auditory sensory cues to speech rhythm and prosody could lead developmentally to impairments in phonology. We compared matched samples of children with and without dyslexia, learning three very different spoken and written languages, English, Spanish, and Chinese. The key sensory cue measured was rate of onset of the amplitude envelope (rise time), known to be critical for the rhythmic timing of speech. Despite phonological and orthographic differences, for each language, rise time sensitivity was a significant predictor of phonological awareness, and rise time was the only consistent predictor of reading acquisition. The data support a language-universal theory of the neural basis of developmental dyslexia on the basis of rhythmic perception and syllable segmentation. They also suggest that novel remediation strategies on the basis of rhythm and music may offer benefits for phonological and linguistic development.
The complete mitochondrial genome of Lucioperca lucioperca (Perciformes: Percidae)

Abstract The complete nucleotide sequence of the mitochondrial genome of Lucioperca lucioperca was cloned and sequenced in this study, which contained 16,542 bp. Results showed that the sequence was made up of 13 proteins, 22 transfer RNAs and 2 ribosomal RNA genes. The control region and the origin of the light strand replication were similar to other vertebrates. All protein-coding genes began with ATG except for COX1 and COX2, the COX1 genes started with ATC and COX2 genes started with ATT, while all of those ended with TAA, TA, T or TAG. The result could be used in related studies such as molecular ecology and evolutionary biology.
PROPOLIS AND BEE VENOM IN DIABETIC WOUNDS; A POTENTIAL APPROACH THAT WARRANTS CLINICAL INVESTIGATION

Background: Wound healing in diabetes mellitus is a complex multi-stage process that requires the proper function of multiple systems. The mechanisms of impaired wound healing of diabetic wounds are still poorly understood. Therefore, various interventions are being used for wound management without great success. Bee products have various properties that make them an important addition to the diabetic wound management. Methods: This review summarized previous and recently published papers of the effects of two bee products, propolis and bee venom, on the wound healing. The main results were obtained from preclinical experimentation. Results: Diabetes mellitus compromises immune system, increases infections, impairs wound healing, and affects cells and factors involved in the wound healing. There is an increasing interest in natural products in modern medicine as part of disease management. Bee products are natural substances that others and we have explored some of their biological activities and applications in the treatment of various diseases. Some of these products are bee venom and propolis. These products have analgesic, antioxidant, antimicrobial, and anti-inflammatory properties. In addition, both propolis and bee venom contain considerable amounts of antioxidants that have a great role in accelerating wound healing. Conclusion: There is sound rationality and scientific data for using propolis and bee venom in diabetic wound healing. We believe that topical application of propolis in addition to bee venom might have a place in repairing damaged tissues and accelerating the healing of diabetic wounds.