Miracle-dz/UniFAR-FTUs huggingface dataset:
Responsiveness to staff support: evaluating the impact of individual characteristics on the effectiveness of active support training using a conditional probability approach.

BACKGROUND Active support training was fully conducted in 38 community houses accommodating 106 adults with intellectual disabilities (ID; group 1), but not in a further 36 accommodating 82 adults with ID (group 2). The aims of the present study were to analyse whether staff became more effective in supporting resident activity after the implementation of active support, and whether there was evidence of differential responsiveness by people with differing status in relation to adaptive behaviour, psychiatric diagnosis, challenging behaviour or autism. METHODS Observations of staff:resident interaction and resident engagement in activity were taken before and after active support training. Changes in Yule's Q statistics, indicating the likelihood that resident engagement in activity followed staff giving residents verbal instruction or non-verbal assistance, were compared for the two groups. In addition, changes in similar statistics were compared for residents within group 1: (1) with Adaptive Behaviour Scale (ABS) scores above and below 180; and (2) with and without severe challenging behaviour, the triad of social impairments and mental illness. RESULTS Yule's Q for engagement given non-verbal assistance significantly increased post-training among group 1, but not among group 2. Similar significant increases were found among group 1 residents with ABS scores below 180 without challenging behaviour, with and without the triad of social impairments, and without mental illness, but not with an ABS score above 180, with challenging behaviour and with mental illness. CONCLUSION The present analysis reinforces previous studies on the effectiveness of active support training for adults with more severe ID (i.e. with ABS scores below 180). Active support was as effective for people with the triad of social impairments as for those without it. However, the effectiveness of support offered to people with challenging behaviour or mental illness did not significantly increase.
Excitatory Connections Between CA1 Pyramidal Cells Revealed by Spike Triggered Averaging in Slices of Rat Hippocampus are Partially NMDA Receptor Mediated

Spike triggered averaging was used to record local circuit connections between pairs of CA1 pyramidal neurons in isolated slices of rat hippocampus. Of 795 pairs of neurons tested, six were connected. These epsps were only partially blocked by 2‐amino‐5‐phosphonovalerate (AP‐5), which decreased the amplitude and half width of the epsp, but did not affect the early rising phase. In contrast, 6‐cyano‐7‐nitroquinoxaline‐2,3‐dione (CNQX) blocked all phases of the epsp and combinations of AP‐5 and CNQX blocked the epsp almost entirely. These results indicate that these epsps were mediated by both N‐methyl‐d‐aspartate (NMDA) and non‐NMDA excitatory amino acid receptors. Moreover, they exhibited a voltage relation typical of neuronal responses to NMDA, increasing in amplitude and duration as the postsynaptic cell was depolarized. These epsps were brief (10–90% rise time < 5 ms, width at half amplitude < 20 ms), indicating a proximal location. Increasing presynaptic firing rate (1–4 spikes/s) reduced average epsp amplitude by almost 50%. When epsps were evoked by pairs of spikes (interval 3–25 ms), a large response to the first spike precluded a large response to the second. No evidence for selective enhancement of the NMDA receptor component by paired spike activation was found. It is concluded that a significant NMDA receptor mediated input to CA1 is provided by local circuit CA1–CA1 connectionsx and that these synapses can be demonstrated under control conditions.
Hormone Replacement Therapy Should Be Administered as Secondary Prevention of Coronary Artery Disease

* Coronary artery disease in women is associated temporally with the occurrence of menopause and loss of estrogen. * Consistently, epidemiologic evidence indicates a beneficial effect of HRT on the development of CAD (primary prevention). * Observational data in women with known CAD indicate improved angioplasty and mortality outcomes in women taking HRT. * The HERS was fraught with methodologic flaws that drastically hampered the ability of HRT to show benefit as secondary prevention for cardiovascular disease. Despite this, mortality benefit was suggested with long-term therapy.
Wideband Perforated Dense Dielectric Patch Antenna Array for Millimeter-Wave Applications

A wideband perforated dense dielectric (DD) patch antenna array fed by a single-layered substrate integrated waveguide (SIW) feed network is investigated for millimeter-wave applications. The proposed antenna array offers advantages of wide bandwidth and good radiation performance simultaneously and can be fabricated conveniently by the standard printed circuit board (PCB) technology. A 4 × 4 prototype operated at the 60-GHz band is designed, fabricated, and measured to demonstrate the design. An impedance bandwidth of 23% for SWR <; 2, a gain up to 17.5 dBi with a 3-dB gain bandwidth of 24%, symmetrical unidirectional radiation patterns with cross polarization levels of less than -20 dB are achieved.
Increased oxidative DNA damage, inducible nitric oxide synthase, nuclear factor kappaB expression and enhanced antiapoptosis-related proteins in Helicobacter pylori-infected non-cardiac gastric adenocarcinoma.

AIM Several epidemiological studies have demonstrated a close association between Helicobacter pylori (H pylori) infection and non-cardiac carcinoma of the stomach. H pylori infection induces active inflammation with neutrophilic infiltrations as well as production of oxygen free radicals that can cause DNA damage. The DNA damage induced by oxygen free radicals could have very harmful consequences, leading to gene modifications that are potentially mutagenic and/or carcinogenic. The aims of the present study were to assess the effect of H pylori infection on the expression of inducible nitric oxidative synthase (iNOS) and the production of 8-hydroxy-deoxyguanosine (8-OHdG), a sensitive marker of oxidative DNA injury in human gastric mucosa with and without tumor lesions, and to assess the possible factors affecting cell death signaling due to oxidative DNA damage. METHODS In this study, 40 gastric carcinoma specimens and adjacent specimens were obtained from surgical resection. We determined the level of 8-OHdG formation by HPLC-ECD, and the expression of iNOS and mechanism of cell death signaling (including nuclear factor-kappaB(NFkappaB), MEKK-1, Caspase 3, B Cell lymphomal leukemia-2 (Bcl-2), inhibitor of apoptosis protein (IAP) and myeloid cell leukemia-1 (Mcl-1)) by Western-blot assay. RESULTS The concentrations of 8-OHdG, iNOS, NFkappaB, Mcl-1 and IAP were significantly higher in cancer tissues than in adjacent non-cancer tissues. In addition, significantly higher concentrations of 8-OHdG, iNOS, NFkappaB, Mcl-1 and IAP were detected in patients infected with H pylori compared with patients who were not infected with H pylori. Furthermore, 8-OHdG, iNOS, NFkappaB, Mcl-1 and IAP concentrations were significantly higher in stage 3 and 4 patients than in stage 1 and 2 patients. CONCLUSION Chronic H pylori infection induces iNOS expression and subsequent DNA damage as well as enhances anti-apoptosis signal transduction. This sequence of events supports the hypothesis that oxygen-free radical-mediated damage due to H pylori plays a pivotal role in the development of gastric carcinoma in patients with chronic gastritis.
Comparison of predictive models to predict survival of cardiac surgery patients

With recent innovation in computer database technology, voluminous data related to cardiac surgery are easily stored and made available for further analysis. However, these large quantities of data are often not fully utilized in terms of modelling cardiac surgery outcomes. Most of the previous studies have mainly focused on applying statistical techniques to small sample of data in order to reveal the simple linear relationships between the factors and survival of cardiac patients. Data mining offers a significant advantage over conventional statistical techniques which often requires the normality assumption. This study developed and compared new models to predict the survival of cardiac surgery patients. The dataset consists of 5154 observations with 23 variables, as suggested by domain experts from a renowned heart-surgery centre in Malaysia. After the data cleaning process, a total of 4976 cases and 12 variables were used for further analysis. The three predictive models, namely; Logistic Regression, Decision Tree and Artificial Neural Network, were developed and compared using the classification accuracy rate, sensitivity and specificity. From the Logistic Regression using ENTER selection model, the whole sample with 4976 cases had an imbalanced class case which led to biased results. Therefore, using the undersampling technique suggested by [14], a sample of 1209 cases (17% died and 83% alive) was used and further analysis was performed using this sample. Results showed that Artificial Neural Network is the best predictive model with classification accuracy, sensitivity and specificity of 88.4%, 95.67% and 58.06% respectively.
Safety of labor induction with prostaglandin E2 in grandmultiparous women

Objective: The aim of this study was to assess the safety of labor induction with vaginal prostaglandin E2 (PGE2) in grandmultiparous women. Methods: We conducted a retrospective cohort study of 1376 grandmultiparous women who underwent induction of labor with low dose PGE2. The primary outcome was uterine rupture and secondary outcomes included mode of delivery, postpartum hemorrhage and five minutes Apgar score. Results: One case was diagnosed with uterine rupture (0.07%). Vaginal delivery was achieved in 1329 (96.6%) patients, whereas 47 (3.4%) patients had emergent cesarean delivery. Five minutes Apgar score ≤7 was recorded in three cases (0.2%). There was no correlation between parity and cesarean delivery rate or low Apgar score. There were no significant differences between the grandmultiparous and great-grandmultiparous patients regarding cesarean delivery rate (3.1 vs. 5%, P = 0.12), operative vaginal delivery rate (2 vs. 2.3%, P = 0.74) or postpartum hemorrhage rate (0.8 vs. 1.1%, P = 0.6). Conclusions: Low dose PGE2 is a safe and efficient method for induction of labor in grandmultiparous and great-grandmultiparous women.
Research on Food Complains Document Classification Based-on Topic

In this paper, we design a classifier based-on topic for food complain documents, and take a series of measures to the implementation process. In order to accomplish feature reduction, the filter method named term filtering for independent topic features is proposed to compress each topic feature vector. We introduce the created food ontology as background knowledge and to expand the semantic of complaint documents with the aid of HowNet. So we can supplement effective information and improve the effect of text classification. In addition, we take account of different importance between title and body in the text, considering that title can stand out the topic of text better than the textual body. Consequently, we separately calculate the word frequency which words are in textual title and body. The experiments show that it is necessary to consider the different importance between textual title and body, and we can achieve good feature reduction effect using the proposed filter method, and the classification performance get obvious improvement after the process of term expanding.
Twitter 911 : A Cautionary Tale

Researchers have argued that social media, and in particular, Twitter, can be searched to improve “situational awareness” in emergency situations; that is, to provide objective, actionable, real-time information to first-responders. Prior studies have examined cases of very rare, catastrophic emergencies that took place over many days, such as the aftermath of Hurricane Sandy. We asked instead if Twitter could provide useful information for first-responders on a more regular basis, by conducting an exhaustive analysis of tweets and fire department data for medium-sized county (population 1 million), and for two larger-scale single-day emergencies in New York City. Our results are resoundingly negative: useful tweets were extraordinarily rare or nonexistence. This study provides a cautionary note as to the potential of Twitter and similar platforms for emergency situational awareness. Social media posts are routinely analyzed to uncover the beliefs, preferences, and behavior of a large segment of the world’s population, and to reveal how opinions and information percolate through social networks. Some researchers have argued that data mining social media can go beyond gathering subjective and idiosyncratic information, but can also yield objective, actionable, real-time data, for applications such as emergency response and ensuring public health. The existence of a few well-publicized cases of users tweeting or blogging reports from war zones or disaster areas reinforces the notion that social media can be used as a kind of distributed sensor network. Does this impression match reality? We conducted two systematic studies to determine whether Twitter data could be used to enhance emergency response. In the first, we analyzed all posts from a medium-sized metropolitan area to find ones related to fires recorded in the area’s 911 emergency report system over the course of six months. In the second study, we exhaustively searched tweets about two disasters in New York City, the collapse of a construction crane in midtown and a gas explosion in the East Village. Both studies came to the same conclusion: there were essentially no timely, first-hand user posts about any of the events. The vast majority of related posts were retweets of posts that originated from emergency response organizations themselves. A few users tweeted images of the emergency situations long after first-responders Copyright c © 2017, Association for the Advancement of Artificial Intelligence (www.aaai.org). All rights reserved. were already on the scene. While any limited set of studies cannot prove a negative, we believe ours provide a cautionary note about the potential for social media to be useful for gathering, as opposed to disseminating, objective information. We discuss reasons for this, such as the personal nature of social media and methodological limitations of prior work.
Financial Inclusion and Economic Growth in WAEMU: A Multiscale Heterogeneity Panel Causality Approach

This paper examines the causal relationship between Financial Inclusion and economic growth in the West African Economic and Monetary Union (WAEMU) from 2006 to 2015. We combined the heterogeneity panel causality test proposed by [1] with the Maximal Overlap Discrete Wavelet Transform (MODWT) to analyze the bi-directional causality at different time scales. We used two Financial Inclusion indicators: the overall rate of demographic penetration of financial services (Financial Inclusion supply) and the overall rate of use of financial services (Financial Inclusion demand). Our results show that at scale 1 (2 - 4 years), there is no causality between economic growth and Financial Inclusion indicators. However, at scale 2 (4 - 8 years), we found a bi-directional causality between economic growth and Financial Inclusion. Policymakers should therefore promote reforms that are beneficial to financial inclusion, especially on the supply side, while making the levers for macroeconomic growth more efficient, which also seems to be a decisive factor in financial inclusion.
The Polish accounting system and IFRS implementation process in the view of empirical research

The paper analyses the process of implementing International Financial Reporting Standards (IFRS) in Poland. It presents the development of accounting in its historical perspective focusing on such events as the partitions of Poland, wars, the period of the centrally planned economy, the period of the political and economic transformation and Poland’s membership in the European Union. The authors discuss the relationships between tax and financial accounting and identify the main users of information generated by the accounting system; also, they describe the Polish capital market as well the organizations which contribute to the development of accounting. The further part of the work presents the scope of IFRS implementation, identifying four stages of the process as well as the entities which apply international standards. The paper stresses that Polish accounting regulations are based on the simultaneous implementation of IFRS convergence and adoption. The authors point to a number of benefits derived by companies from IFRS implementation including the higher quality of financial statements and their comparability, lower costs of capital as well. Also, the authors present an extensive review of literatures and the results of major empirical research in the area of IFRS implementation in Poland.
Investigation of polymorphisms in the CREM gene in panic disorder

Clinical and animal studies suggest a role for pathways regulated by cyclic‐AMP in anxiety. Mouse gene deletion studies, our own linkage findings on chromosome 10, and a recently published genetic association study by Domschke et al. [2003: Am J Med Genet 117B:70–78] suggest that the cAMP responsive element modulator (CREM) may be involved in panic disorder. We have employed a family‐based design to investigate the role of DNA sequence variations in the gene for CREM in panic disorder. We have genotyped 613 individuals in 70 panic disorder pedigrees, as well as 42 parent/offspring triads. Subjects were genotyped at two informative single nucleotide polymorphisms (SNPs) and three polymorphic microsatellites in the CREM genomic region; and the data were analyzed for genetic association and linkage. Linkage analysis employing several diagnostic/genetic models produced a maximum lod score of 0.63 for SNP‐1, located in the 5′ UTR of CREM, under a dominant model with a broad diagnostic definition of panic disorder. Non‐parametric analysis, using the NPL statistic or FBAT, also did not support any linkage or association between the markers and panic disorder. All five markers (spanning 77 kb) used in the study showed modest, but significant linkage disequilibrium. Analysis of 2‐, 3‐, 4‐, or 5‐marker haplotypes using TRANSMIT failed to find any globally significant results; however, individual haplotypes containing a single allele of MS‐3 were nominally associated with panic disorder. These findings provide little additional evidence for a susceptibility locus for panic disorder either within the CREM gene or in a nearby region of chromosome 10p11 in our sample. © 2003 Wiley‐Liss, Inc.
Review of Active Power Decoupling Topologies in Single-Phase Systems

Active power decoupling methods are developed to deal with the inherent ripple power at twice the grid frequency in single-phase systems generally by adding active switches and energy storage units. They have obtained a wide range of applications, such as photovoltaic (PV) systems, light-emitting diodes (LEDs) drivers, fuel cell (FC) power systems, and electric vehicle (EV) battery chargers, etc. This paper provides a comprehensive review of active power decoupling circuit topologies. They are categorized into two groups in terms of the structure characteristics: independent and dependent decoupling circuit topologies. The former operates independently with the original converter, and the latter, however, shares the power semiconductor devices with the original converter partially and even completely. The development laws for the active power decoupling topologies are revealed from the view of “duality principle,” “switches sharing,” and “differential connection. ” In addition, the exceptions and special cases are also briefly introduced. This paper is targeted to help researchers, engineers, and designers to construct some new decoupling circuit topologies and properly select existing ones according to the specific application.
Intraoperative angiography for emergency cerebrovascular surgery using an exclusively developed radiolucent Sugita head frame and fixation

Intraoperative angiography during emergency cerebrovascular surgery, clipping operation for acute aneurysmal subarachnoid hemorrhage, is reported. For acquisition of intraoperative angiography, an exclusively developed radiolucent version of a Sugita head frame, made of engineering plastics for angiography, and an ordinary fluoroscopic unit were installed. In a radiolucent head frame, all the parts of the ordinary metallic Sugita multipurpose head frame, fixation and its accessories were made of high-molecular polymer plastics in the same size. In emergency cerebrovascular surgery, the radiolucent Sugita frame enabled us to carry out meticulous dissection and precise retraction control as the ordinary metallic system and to perform the intraoperative angiography if needed.
High Uric Acid Induces Insulin Resistance in Cardiomyocytes In Vitro and In Vivo

Clinical studies have shown hyperuricemia strongly associated with insulin resistance as well as cardiovascular disease. Direct evidence of how high uric acid (HUA) affects insulin resistance in cardiomyocytes, but the pathological mechanism of HUA associated with cardiovascular disease remains to be clarified. We aimed to examine the effect of HUA on insulin sensitivity in cardiomyocytes and on insulin resistance in hyperuricemic mouse model. We exposed primary cardiomyocytes and a rat cardiomyocyte cell line, H9c2 cardiomyocytes, to HUA, then quantified glucose uptake with a fluorescent glucose analog, 2-NBDG, after insulin challenge and detected reactive oxygen species (ROS) production. Western blot analysis was used to examine the levels of insulin receptor (IR), phosphorylated insulin receptor substrate 1 (IRS1, Ser307) and phospho-Akt (Ser473). We monitored the impact of HUA on insulin resistance, insulin signaling and IR, phospho-IRS1 (Ser307) and phospho-Akt levels in myocardial tissue of an acute hyperuricemia mouse model established by potassium oxonate treatment. HUA inhibited insulin-induced glucose uptake in H9c2 and primary cardiomyocytes. It increased ROS production; pretreatment with N-acetyl-L-cysteine (NAC), a ROS scavenger, reversed HUA-inhibited glucose uptake induced by insulin. HUA exposure directly increased the phospho-IRS1 (Ser307) response to insulin and inhibited that of phospho-Akt in H9C2 cardiomyocytes, which was blocked by NAC. Furthermore, the acute hyperuricemic mice model showed impaired glucose tolerance and insulin tolerance accompanied by increased phospho-IRS1 (Ser307) and inhibited phospho-Akt response to insulin in myocardial tissues. HUA inhibited insulin signaling and induced insulin resistance in cardiomyocytes in vitro and in vivo, which is a novel potential mechanism of hyperuricemic-related cardiovascular disease.
Managing Work Teams : Evidence from Japanese Cell Production

Cell production that has been adopted in recent years by some of the Japanese manufacturers is based on work teams and it is a replacement for mass production. Focusing on HRM practices, I conducted case study research on that new manufacturing method. I found that the success of a cell line, on which a team of operators was deployed, hinged on (1) multi-skilling, (2) task and goal interdependence, (3) continuous improvement, and (4) extrinsic and intrinsic motivation. There was a set or system of HRM practices to meet these behavioral requirements for implementing cell production—which I called the “perfectly-tapping-potentiality HR system”. Cell lines supported by the HR system were superior especially in terms of delivery time and quality manufacturing performance measures while de-skilled cell lines were relatively more cost-advantageous in the sense that they enjoyed the economy of scale. Fit of HR systems with manufacturing strategies was discussed.