Miracle-dz/UniFAR-FTUs huggingface dataset:
Procambial Initiation for the Vascular System in the Spike of Wheat

Analysis of serial sections of procambial traces in spike primordia of Triticum reveals the early development of the vascular system of the rachis. Alternating pairs of traces form in isolation in the rachis in relation to the lower ridge leaf of each double ridge. Vertical merger of these procambial strands creates the lateral trace system consisting of two vertical traces in the rachis. The central trace system differentiates between but on both sides of the lateral traces, forming an ellipse in transection. Like the lateral traces, the central traces form in isolated pairs in the rachis in relation to their lower ridge leaves. Vertical mergers of the central trace procambia create the vertical lateral trace system along both sides of the rachis. As the lateral and central traces are differentiating and merging, isolated traces differentiating basipetally from the glume insertions begin to link the spikelet with the rachis. Glume traces tend to merge with the earliest available traces in the rachis. This pattern of merger frequently causes the distal spikelets to become linked to the lateral trace system and the proximal spikelets to become linked to the central trace system. In Triticum and other pooid grasses, the lower ridge leaves initiate the vascular system for the rachis as do the vegetative leaves for the culm. The vascular system of the inflorescences of panicoid grasses may have different sites promoting procambial differentiation than do the inflorescences of pooid grasses.
Odontophrynus barrioi , a New Species of Anuran from Argentina

-A new species of Odontophrynus from 2200 m altitude in the Sierra de Famatina, Argentina, is described. Morphological as well as cytogenetic features differentiate the new species, 0. barrioi, from the populations of the 0. occidentalis group. The genus Odontophrynus is widespread in several regions of southern and eastern South America. In arid and subarid territories of western Argentina, Odontophrynus occidentalis (Berg, 1898) is predominant, sympatric with 0. americanus in the eastern pampean boundaries. The range of the group extends in subandean areas along the Cordilleran Mountains, at 500 to 2000 m of altitude in Catamarca and the La Rioja Mountains in the north. Southwards it reaches northern Patagonia in Rio Negro and Neuquen Provinces, but marginal populations are also found eastwards in the pampean reliefs of the Sierras of Cordoba and San Luis and on the sandy Atlantic coasts of Buenos Aires Province (Savage and Cei, 1965; Barrio, 1964; Cei, 1980a) (Fig. 1). Having in mind the characteristic cytogenetic features of 0. americanus whose diploid-tetraploid populations were described by Beqak et al. (1966, 1970), a comparative populational study on 0. occidentalis was carried out. During this study polyploid populations of 0. occidentalis were not detected. However, significant karyotypic differences in heterochromatin patterns were found between an isolated population from the extra-Andean Famatina massif in La Rioja Province, and several other populations ranging from Mendoza to the southernmost localities in the species distribution (Ruiz et al., in press). Besides the karyotypic differences, these populations are different in several morphological and biological characteristics. The isolated population from the La Rioja Mountains lies in a geographical area characterized by striking endemisms (Cei, 1980b), and is described as a new form of the genus. Holotype and paratypes are deposited in the Zoological Museum of the University of Sao Paulo (MZUSP). Odontophrynus barrioi sp. nov. (Fig. 2) Holotype. -MZUSP 57635. An adult male, from Aguadita springs, 2200 m, 30 km north of the village of Famatina, Sierra de Famatina, La Rioja Province, Argentina, collected on 17 November 1978 by J. M. Cei. Paratypes. -MZUSP 57635-57638, two adult males; 57636-57639, two adult females; 57640-57647; eight juvenile specimens; all the same data as the holotype. Definition. -A stout Odontophrynus of the occidentalis group, characterized by small, high head; nostril very near tip of snout; diameter of eye about equal to its distance from nostril; interorbital distance about one-half width of upper eyelid; no well defined parotoid glands; irregularly arranged rounded glandular warts; lateral fringes poorly developed on fingers; metatarsal tubercle shovellike, moderately developed; short foreThis content downloaded from 157.55. 39.235 on Fri, 07 Oct 2016 05:54:17 UTC All use subject to http://about.jstor. org/terms
Re-analysis confirms the polyphyly of Lamprotula Simpson, 1900 (Bivalvia: Unionidae)

Zhou et al. (2007, Acta Zoologica Sinica, 53: 1024–1030) reported the eastern Asian freshwater mussel genus Lamproula sensu lato Simpson, 1900 (Unionidae) to be polyphyletic and advocated a revision of the genusand family-level classifications. However, their taxon sampling and analyses were insufficient to infer accurately the systematic placement of the resultant clades. We reanalysed their mtDNA ND1 and 16S sequences in a broader phylogenetic context. In addition to nine putative species of Lamprotula s. l. , we sampled genera from five of six unionid subfamilies as well as two outgroup families (34 species in total). Both character partitions were analysed separately and in combination under maximum parsimony and maximum likelihood, and combined matrices were also examined using Bayesian inference. Our results confirm support for polyphyly among the species of Lamprotula s. l. , with genus-level clades recovered in two different unionid subfamilies. The taxonomic implications of recognizing two genera, Lamprotula sensu stricto (subfamily Gonideinae) and Aculamprotula Wu, Liang, Wang & Ouyang, 1999 (subfamily Unioninae), are discussed, as are anomalies discovered in the published data. It is concluded that, while Lamprotula s. l. is polyphyletic, a more comprehensive revision is necessary to determine the valid names for these two genera.
Heat transfer of oxy-fuel flames to glass

Impinging flame jets are commonly used in glass heating processes for cutting, melting and forming purposes. High local heat-transfer rates can be obtained using these flame jets which is preferable, since the processing times of glass products need to be short. To increase the heat-transfer rates, the burners are often supplied with a pure fuel-oxygen mixture resulting in high flame temperatures and high gas velocities compared to a fuel-air mixture. However, flame impingement is a very complex process where fluid dynamics, thermodynamics and chemical kinetics all play an important role. These phenomena need deeper understanding before the process can be analyzed, to avoid high thermal stresses and overheating of the hot spots of the glass products. Four regions can be distinguished in the flow structure of an impinging flame jet: a flame jet region, a free jet region, a stagnation region and a wall jet region. Since the typical time scales of the regions differ, each region can be decoupled, treated separately and coupled again afterwards. Generally, the impinging flame jet is placed close to the product resulting in a laminar burnt gas flow. Since the shell thickness of the glass tubes is significantly smaller than the radius of the tubes, the glass product can be approximated by a flat plate. A relation has been derived which relates the burner radius and the unburnt gas velocity on the one hand to the burnt gas jet radius and the burnt gas velocity on the other. By that, the relation couples the flame jet region to the free jet region. An idealized reproduction of the flame front has been used, where the effect of flame curvature was neglected and where the velocity profile at the exit of the burner nozzle was assumed to be flat. By solving the global conservation equations of mass, momentum and energy, the relation between the above mentioned parameters was derived. Experimental validation using Particle Image Velocimetry showed good agreement, especially for the oxy-fuel
Systematics of Spilanthes (Compositae: Heliantheae)

Spilanthes is widespread throughout the New and Old World tropics. Morphological and chromosomal evidence supports separation of the genus into two genera, Spilanthes and Acmella, which can be distinguished by at least eight morpho- logical characters and by distinctive basic chromosome numbers. Studies of other genera within the Heliantheae suggest that both Spilanthes and Acmella are allied to Salmea in the Verbesininae. Spilanthes is here recognized as comprising six species distributed primarily in sandy soils of South America, the West Indies, northern Australia, Malaysia, and central and western Africa. A phylogenetic reconstruction employing cladistic methods suggests that the New World species, S. leiocarpa, S. nervosa, S. paraguayensis, and S. urens, are more closely allied to each other than to the Old World species. The cladistic analysis further suggests a closer relationship between the Australo-Malaysian S. anactina and the New World species than with S. costata, a species restricted to central and western tropical Africa. Spilanthes Jacq. (sensu Moore 1907) is primarily a weedy genus of 30- 40 species of Compositae (Heliantheae) in the New and Old World trop- ics. The genus has been traditionally divided into two sections, Spilanthes and Acmella Rich. (de Candolle 1836; Moore 1907). Morphological and chromosomal studies (Jansen 1979; Jansen and Stuessy 1980) suggest that these sections merit recognition at the generic level. From this view- point Acmella contains approximately 30 species and is currently being revised (Jansen in progress). Spilanthes is here recognized as comprising six species distributed primarily in sandy soils of South America, the West Indies, northern Australia, Malaysia, and central and western Af- rica. The present investigation clarifies generic relationships of Spilanthes in relation to Acmella, presents the taxonomy of the six species of Spi- lanthes, and develops a phylogenetic reconstruction of these species using
Evaluation of medicinal herbs as a potential therapeutic option against SARS‐CoV‐2 targeting its main protease

The COVID‐19 disease caused by the SARS‐CoV‐2 has emerged as a worldwide pandemic and caused huge damage to the lives and economy of more than hundred countries. As on May 10, 2020, more than 4,153,300 people stand infected from the virus due to an unprecedented rate of transmission and 282,700 have lost their lives because of the disease. In this context, medicinal plants may provide a way to treat the disease by targeting specific essential proteins of the virus. We screened about 51 medicinal plants and found that Tea (Camellia sinensis) and Haritaki (Terminalia chebula) has potential against SARS‐COV‐2 3CLpro, with an IC50 for Green Tea as 8.9 ± 0.5 μg/ml and Haritaki 8.8 ± 0.5 μg/ml. The in‐silico studies suggested that Tea component Thearubigins binds to the cysteine 145 of protease active site and could be a pharmacoactive molecule. We predict that the inhibition in protease activity may be able to halt the SARS‐CoV‐2 replication cycle and therefore, we propose Green Tea, Black Tea, and Haritaki plant extracts as potential therapeutic candidates for SARS‐CoV‐2 infection. Further investigation on role of bioactive constituents of extracts is needed to establish the molecular basis of inhibition and towards expedited drug discovery.
Challenges Faced by Female Healthcare Professionals in the Workforce: A Scoping Review

Background The number of women entering the medical and healthcare workforce globally has increased in the past several decades. Women have many roles and positions in healthcare organizations, hospitals and healthcare education settings. Although there has been an increase in the number of women, female workers continue to face many workplace challenges. This scoping review aimed to explore the challenges female healthcare professionals face in the workforce. Methods A scoping review utilizing Arksey and O’Malley’s six-step framework was undertaken to identify and map available literature addressing challenges faced by female healthcare professionals in the workforce. The databases searched included Embase, EmCare, Medline, Cumulative Index of Nursing and Allied Health Literature (CINAHL) and Business Source Complete (BSC). Additional searches were performed using Google Scholar, Trove and grey literature. Results The initial search yielded 2455 publications (Medline n=369; EmCare n=276; Embase n=612; CINAHL n=1088; Business Source Complete n=109; mixed grey literature n=1). After removal of duplicates, 1782 citations remained. Abstract and title screening reduced the field to 36 publications, following which full-text reviews were conducted. Consensus was reached on 16 publications for final review. After analyzing the articles, three themes were identified: i) family responsibilities, ii) workplace environment and iii) stereotyping. Conclusion Findings confirm that female healthcare professionals face circumstances that may affect their family lives, as well as factors relating to the workplace environment and stereotypes. Implementing strategies such as reduced work hours, flexible timing and part-time work can support women in the workplace, which then enhances and supports gender equality in healthcare organizations.
A Systematic Review on Clinimetric Properties of Play Instruments for Occupational Therapy Practice

Play is considered the main occupation for children. Pediatric occupational therapists utilize play either for evaluation or intervention purpose. However, play is not properly measured by occupational therapists, and the use of play instrument is limited. This systematic review was aimed at identifying play instruments relevant to occupational therapy practice and its clinimetric properties. A systematic search was conducted on six databases (Academic Search Complete, CINAHL, MEDLINE, Psychology and Behavioral Science Collection, Scopus, and ASEAN Citation Index) in January 2020. The quality of the included studies was evaluated using Law and MacDermid's Appraisal for Clinical Measurement Research Reports, and psychometric properties of play instruments were evaluated using Terwee's checklist while the clinical utility is extracted from each instrument. Initial search identifies 1,098 articles, and only 30 articles were included in the final analysis, extracting 8 play instruments. These instruments were predominantly practiced in the Western culture, which consists of several psychometric evidences. The Revised Knox Preschool Play Scale is considered the most extensive and comprehensive play instrument for extrinsic aspect, whereas the Test of Playfulness + Test of Environmental Supportiveness Unifying Measure is a promising play instrument for intrinsic aspect on play, where both instruments utilize observation. My Child's Play is a potential questionnaire-based play instrument. However, the current development of play instruments in the occupational therapy field is immature and constantly evolving, and occupational therapists should exercise good clinical reasoning when selecting a play instrument to use in practice.
DISSEMINATION OF SEED FROM EUCALYPTUS REGNANS

SUMMARY Wind is the only important agent of dispersal of E. regnans F. Muell. seed and most seed is disseminated in the direction of the locally prevailing winds. Seed-trapping studies over several years have shown that dissemination is poor from the edge of a dense forest, but much better from isolated trees. The degree to which the local winds are deflected and obstructed is obviously important. It is concluded that adequate coverage of self-sown seed cannot be expected on completely felled areas which are more than two or three chains wide. Adequate distribution of seed from isolated trees probably depends more on amount of available seed than on efficiency of dissemination.
The effect of staying at home due to COVID‐19 outbreak on nursing students' life satisfaction and social competencies

Abstract Purpose In this study, it was aimed to investigate the life satisfaction and social competencies of the nursing students. Design and Method Our sample was composed of a nursing group with voluntary participation, internet network connection, and social media use. Findings It was found that there was a significant difference between the mean scores of the students in terms of compliance to stay at home and a positive status of an acquaintance (COVID‐19) (P %3C .01), and there was a significant difference between the students' mean scores at home (P = .01) (P %3C .01). Practice Implications As a result, it was determined that the students were adapted to stay at home, the precautions taken in the epidemic were insufficient and the social competencies of the students were associated only with adaptation to stay.
Hidden in our pockets: building of a DNA barcode library unveils the first record of Myotis alcathoe for Portugal

Abstract Background The advent and boom of DNA barcoding technologies have provided a powerful tool for the fields of ecology and systematics. Here, we present the InBIO Barcoding Initiative Database: Portuguese Bats (Chiroptera) dataset containing DNA sequences of 63 specimens representing the 25 bat species currently known for continental Portugal. For that, we sequenced tissues samples obtained in a vast array of projects spanning the last two decades. New information We added four new Barcoding Index Numbers (BINs) to existing Chiroptera barcodes on BOLD, two belonging to Myotis escalerai, one to Plecotus auritus and the other to Rhinolophus hipposideros. Surprisingly, one of the samples initially identified in the field as Myotis mystacinus turned out to be Myotis alcathoe, which represents the first record of this species for Portugal. The presence of Nyctalus noctula in Portugal was also genetically confirmed for the first time. This case study shows the power and value of DNA barcoding initiatives to unravel new data that may be hidden on biological collections.
Water-Based Scalable Methods for Self-Cleaning Antibacterial ZnO-Nanostructured Surfaces

Bacterial colonization poses significant health risks, such as infestation of surfaces in biomedical applications and clean water unavailability. If maintaining the surrounding water clean is a target, developing surfaces with strong bactericidal action, which is facilitated by bacterial access to the surface and mixing, can be a solution. On the other hand, if sustenance of a surface free of bacteria is the goal, developing surfaces with ultralow bacterial adhesion often suffices. Here we report a facile, scalable, and environmentally benign strategy that delivers customized surfaces for these challenges. For bactericidal action, nanostructures of inherently antibacterial ZnO, through simple immersion of zinc in hot water, are fabricated. The resulting nanostructured surface exhibits extreme bactericidal effectiveness (9250 cells cm–2 h–1) that eliminates bacteria in direct contact and also remotely through the action of reactive oxygen species. Remarkably, the remote bactericidal action is achieved without the need for any illumination, otherwise required in conventional approaches. As a result, ZnO nanostructures yield outstanding water disinfection of >99.98%, in the dark, by inactivating the bacteria within 3 h. Moreover, Zn2+ released to the aqueous medium from the nanostructured ZnO surface have a concentration of 0.73 ± 0.15 ppm, markedly below the legal limit for safe drinking water (5–6 ppm). The same nanostructures, when hydrophobized (through a water-based or fluorine-free spray process), exhibit strong bacterial repulsion, thus substantially reducing bacterial adhesion. Such environmentally benign and scalable methods showcase pathways toward inhibiting surface bacterial colonization.
Epigenetic Modulation by Apabetalone Counters Cytokine-Driven Acute Phase Response In Vitro, in Mice and in Patients with Cardiovascular Disease

Chronic systemic inflammation contributes to cardiovascular disease (CVD) and correlates with the abundance of acute phase response (APR) proteins in the liver and plasma. Bromodomain and extraterminal (BET) proteins are epigenetic readers that regulate inflammatory gene transcription. We show that BET inhibition by the small molecule apabetalone reduces APR gene and protein expression in human hepatocytes, mouse models, and plasma from CVD patients. Steady-state expression of serum amyloid P, plasminogen activator inhibitor 1, and ceruloplasmin, APR proteins linked to CVD risk, is reduced by apabetalone in cultured hepatocytes and in humanized mouse liver. In cytokine-stimulated hepatocytes, apabetalone reduces the expression of C-reactive protein (CRP), alpha-2-macroglobulin, and serum amyloid P. The latter two are also reduced by apabetalone in the liver of endotoxemic mice. BET knockdown in vitro also counters cytokine-mediated induction of the CRP gene. Mechanistically, apabetalone reduces the cytokine-driven increase in BRD4 BET occupancy at the CRP promoter, confirming that transcription of CRP is BET-dependent. In patients with stable coronary disease, plasma APR proteins CRP, IL-1 receptor antagonist, and fibrinogen γ decrease after apabetalone treatment versus placebo, resulting in a predicted downregulation of the APR pathway and cytokine targets. We conclude that CRP and components of the APR pathway are regulated by BET proteins and that apabetalone counters chronic cytokine signaling in patients.
miR-30d Induced Apoptosis by Targeting Sox4 to Inhibit the Proliferation, Invasion and Migration of Nephroblastoma

Background Wilms tumor (WT) is an embryonic malignant tumor, and its related mechanism is still unclear. microRNA (miR), as a short-chain non-coding RNA, has low expression in various tumors. In this study, WT differential miR was screened by multi-chip in GEO database and its mechanism was explored to provide potential therapeutic targets and ideas for clinic. Methods We logged into GEO database and downloaded GSE57370 and GSE48137 chip matrix files to analyze potential differences in miR. TargetScan, miRDB, miRTarBase and starBase were applied to predict the target genes of miR with significant differences. qRT-PCR was applied to determine the expression of miR-30d and Sox4 in WT tissue and cell line (G401). The interaction of miR-30d with Sox4 was confirmed by qRT-PCR, Western blot and luciferase assay, respectively. CCK-8, Transwell and flow cytometry were applied to determine the proliferation, invasion, migration and apoptosis of cells. Results We found that miR-30d was low expressed in two chips. qRT-PCR showed that miR-30d was down-regulated and SOX4 was up-regulated in WT tissues and cells. The online target gene prediction software showed there was a targeted binding site between Sox4 and miR-30d. Sox4 was negatively controlled by miR-30d. Subsequent studies found that over-expression of miR-30d inhibited the proliferation, invasion, migration and induced apoptosis of C64 and WiT49 cells. In addition, Sox4 could reverse the proliferation, invasion and migration of C64 and WiT49 induced by miR-30d and induce apoptosis. Conclusion miR-30d is poorly expressed in WT and can induce apoptosis and inhibit proliferation, invasion and migration by mediating Sox4.