Miracle-dz/UniFAR-FTUs huggingface dataset:
Computational Studies and Biosynthesis of Natural Products with Promising Anticancer Properties

We present an overview of computational approaches for the prediction of metabolic pathways by which plants biosynthesise compounds, with a focus on selected very prom‐ ising anticancer secondary metabolites from floral sources. We also provide an overview of databases for the retrieval of useful genomic data, discussing the strengths and limita‐ tions of selected prediction software and the main computational tools (and methods), which could be employed for the investigation of the uncharted routes towards the bio‐ synthesis of some of the identified anticancer metabolites from plant sources, eventually using specific examples to address some knowledge gaps when using these approaches.
Estimating bias and RMSE of indirect effects using rescaled residual bootstrap in mediation analysis

It is a common practice to estimate the parameters of mediation model by using the Ordinary Least Squares (OLS) method. The construction of T statistics and confidence interval estimates for making inferences on the parameters of a mediation model, particularly the indirect effect, is usually are based on the assumption that the estimates are normally distributed. Nonetheless, in practice many estimates are not normal and have a heavy tailed distribution which may be the results of having outliers in the data. An alternative approach is to use bootstrap method which does not rely on the normality assumption. In this paper, we proposed a new bootstrap procedure of indirect effect in mediation model which is resistant to outliers. The proposed approach was based on residual bootstrap which incorporated rescaled studentized residuals, namely the Rescaled Studentized Residual Bootstrap using Least Squares (ReSRB). The Monte Carlo simulations showed that the ReSRB is more efficient than some existing methods in the presence of outliers.
Model of soil environment as object of mechanical tillage

Today the foundation of soil treatment is to change its state by means of transferring of physical and mechanical properties of the initial state to the required one. Moreover, the transition process is carried out by simple mechanical impact of a deformer (working body), which is a solid body moving in the soil and disturbing its initial structure due to the interaction with it. As the result of processing is a non-equilibrium state of the soil, in any case, soil tillage is a process to feed it a certain amount of energy to change its properties and achievements in terms of agronomic science optimal addition, at which the maximum effect (e.g., crop yields) is obtained. Thus one of the objectives is to provide tillage supplying energy to the soil in a form and amount sequences that allow it to obtain the required condition, expending less energy as possible. It is desirable to form the energy input as low as possible "cheap", in terms of its availability. [Kapov S.N. , Aduov M.A., Nukusheva S.A. Model of soil environment as object of mechanical tillage. Life Sci J 2014;11(12s):156-161] (ISSN:1097-8135). http://www.lifesciencesite. com. 30
CORPORATE SOCIAL RESPONSIBILITY AS A SUCCESS FACTOR FOR M&A TRANSACTIONS

his paper examines the effect of corporate social responsibility (CSR) on purchasing companies’ success in carrying out an M&A. The possibility of integrating CSR into the M&A process will be investigated and developed using the risk management approach. The resulting hypotheses will be examined empirically in order to produce recommendations for the integration of CSR into the M&A process.
Genetic Study of Quantitative Traits in Spring Wheat Through Generation Means Analysis

2 Abstract: Wheat (Triticum aestivum) is king of cereals and it is the staple food of the people of Pakistan. The gene action controlling drought tolerance in spring wheat is studied by generation means analysis. The parental, back cross, first and second filial generations were grown under the water deficient condition in randomized complete block design using three replications. Data on the quantitative traits were collected from each generation and replication. Heterosis is observed in all the yield predicting parameters like number of tillers per plant, number of grains per spike, 1000 grain weight and grain yield per plant. Generation means analysis revealed presence of additive (d), dominance (h) and epistatic genetic effects in the inheritance of traits. Two parameter model (md) provided the best fit for spike length and number of tillers per plant which shows the presence of additive genetic effect is prominent with simple inheritance while, (ml) showed best fit for grain yield per plant that indicates the non allelic interaction is involved in the inheritance of trait. The remaining traits exhibited higher parameter models and indicating the complex inheritance.
Evaluation of a Multicultural Approach to Teaching Entrepreneurship

Abstract One of the most important challenges in the field of higher education is to educate students about entrepreneurial attitudes and professional competences necessary for working in a multicultural environment in collaboration with a real business environment. Streamlining this process is one of the aims of the Erasmus+ Strategic Partnership Project titled Entrepreneurship and Communication in Multicultural Teams (ECMT+). The cognitive purpose of this paper is to explore and evaluate students’ reflections on entrepreneurship teaching in an international and multicultural team. The applied research methods include a pilot quantitative survey using questionnaires and a qualitative research method of a reflective essay among students participating in the two-week Intensive Programme that took place in March 2017 at Karelia University in Finland. Respondents were chosen purposeful and included 48 participants from 14 countries worldwide. They represented seven high education institutions from seven different European countries. The study has been conducted anonymously via the Claroline Connect platform. The purpose of the empirical research was to diagnose the opinions of program participants, among others about new methods of business education they have experienced, diversity of multicultural context and relationships with other team members, their entrepreneurial attitude, and ability to solve problems at designing business solutions in the multicultural team. Preliminary results appear to present interesting data and may provide a starting point for an in-depth empirical research associated with entrepreneurship in multicultural teams. The study reveals positive effects of applied methods of business education, significant involvement of participants in achieving the goal and gaining new knowledge within the analyzed area.
Approximate Bayesian Computation in hydrologic modeling: equifinality of formal and informal approaches

1) Please do not claim that ABC is “introduced” in this paper. Your recently accepted paper in WRR “introduced” ABC for hydrological applications (Vrugt and Sadegh, 2013). It is fine to have some duplication (in fact, even „needed‟ to understand the paper by itself), but I would be more explicit about the fact that the ABC method is already introduced. This paper for HESS has the nice feature of connecting ABC with GLUE. Yet, that is only mentioned at the bottom of the abstract and end of introduction. I would suggest to bring the connection with GLUE front and center in the HESS-paper to avoid a vague feeling that this is a repeat of the WRR-paper (which is not the case, I checked). Also maybe add on l.161 that this paper is also a follow up of Vrugt and Sadeg 2013, rather than just Vrugt et al (2008c).
AntMonitor: A System for Mobile Network Monitoring

In this thesis, we propose AntMonitor – a complete system for passive monitoring, collection, and analysis of fine-grained, large-scale packet measurements from mobile devices. We design AntMonitor as a VPN-based service, and we develop and compare two versions of the architecture, Client-Server and Mobile-Only. We show that the AntMonitor Mobile-Only prototype significantly outperforms the Client-Server one, as well as all comparable state-of-the-art approaches w.r. t. throughput and energy. It achieves speeds of over 90 Mbps (downlink) and 65 Mbps (uplink), which are 2x and 8x throughput of existing mobile-only approaches, and at 94% of the throughput without VPN. These speeds are achieved while using 2–12x less energy. We also argue that AntMonitor is uniquely positioned to support a number of passive monitoring applications, namely: (i) real-time detection and prevention of private information leakage from the device to the network; (ii) passive performance measurements network-wide as well as per-user; and (iii) application classification based on TCP/IP header features. Furthermore, the Mobile-Only design helps AntMonitor to scale with ease and provides enhanced privacy protection. We present results from a pilot user study at UCI and highlight the key design choices and optimizations that allow AntMonitor to achieve significant benefits.
Complex Bilding Behavior of L-Tryptophan and Related Amino Acids, a Comparative Investigation

The acidity constants of Tryptophan1 were determined by potentiometric pH titration. The stability constants of the 1:1 complexes formed between M2+: Ca2+, Mg2+, Mn2+, Co2+, Ni2+, Cu2+ or Zn2+ and Trp2−, were determined by potentiometric pH titration in aqueous solution (I = 0.1 M, NaNO3, 25°C). The order of the stability constants was reported. It is shown that the stability of the binary M(Trp) complexes is solely determined by the basicity of the carboxyl or amino group. All the stability constants reported in this work show the usual trend. The obtained order is Ca2+ Zn2+. The observed stability order for Tryptophan follows the Irving-Williams sequence. It is shown that regarding to M ion–binding properties vital differences on complex bilding were considered. It is demonstrated, that in M−Trp complexes, M ion is coordinated to the carboxyl group, M ion is also able to bild macrochelate over amino group. The up mentioned results demonstrate that for M−Trp complex the stability constants is also largely determined by the affinity of Cu2+ for amino group. It is shown that Trp can exert a direct influence on reaction mechanism through different kinds of metal ions and donor groups of Trp.
İlişkili Faktörler Correlates of Fatigue and Weakness in Advanced Lung Cancer Patients

Bulgular: Kanser olgularının yorgunluk ve güçsüzlük skorları kontrollerden belirgin derecede daha yüksekti. Pozitif akut faz reaktanları CRP, lökosit, ferritin, trombosit ve fibrinojen, KHDAK grubunda kontrollerden yüksekti. TSH (tiroid-uyarıcı hormon), fT3 (serbest triiodotironin) ve testosteron düzeyleri kanser grubunda kontrollerden daha düşüktü ama kortizol düzeyinde farklılık yoktu. Yorgunluk skoru güçsüzlük skoru, kanserin evresi, lökosit ve trombosit sayıları ile pozitif; vücut kitle indeksi, hemoglobin, fT3, albümin ve transferrin ile negatif korelasyon gösteriyordu. Güçsüzlük skoru kanserin evresi ile pozitif; fT3, albümin ve transferrin düzeyleri ile negatif korelasyon gösteriyordu. CRP ile hem yorgunluk, hem de güçsüzlük skorları arasında pozitif korelasyon saptandı. Yorgunluk ve güçsüzlük skorları ile yaş, sigara yükü, lenfosit, kolesterol, ferritin ve fibrinojen düzeyleri arasında korelasyon yoktu.
Evaluation of the Effect of Pad Thickness and Stiffness on Pressure Non-Uniformity at Die-Scale in ILD CMP

In this study, 2^4 full factorial design of experiment was applied to an FEM model, which gives pattern dependant contact pressure distribution, to build a qualitative model of pad effects on within die non-uniformity (WIDNU) in CMP. Analysis of variance showed that every single effect and two-way interaction effects of hard layer stiffness and soft layer stiffness are significant compared to the round-off error from mesh change. Various regression models were built and residual analyses were done for each of them. Best model with best normality of residuals includes only the effect of hard layer stiffness, soft layer stiffness and hard layer thickness. Based on this model, basic qualitative design rule for a stacked CMP pad to minimize WIDNU were suggested.
An Experimental Study of the Jet of a Boat Propeller

An experimental study of the velocity and concentration (scalar) fields of a propeller is presented. Field and laboratory measurements were undertaken. The former were up to 50 diameters downstream. Important findings were that the mean velocity and scalar fields quickly become Gaussian while further downstream they both become irregular sometimes approaching approximately linear profiles. Propeller turbulence causes rapid mixing giving an initial concentration dilution factor of 1/20,000 after fifty propeller diameters. Some preliminary comparisons with field measurements of an actual boat in a natural waterway are made. Considerably more work is needed to gain a full understanding of the complex problem of propeller mixing.
Analysis and implementation of dynamical system with periodical discrete jumps

The novel method for dynamical motion quantification is discussed in this paper. The proposed approach is verified on the cyclically symmetrical vector field with jump functions generating the large state space attractors recently discovered by the authors. The core part of the calculation engine involves continuous Fourier transform and Cartesian to spherical conversion. It turns out that the existing methods give the incorrect results, have huge demands on the computer performance or completely fail to converge in the finite time. The fully analog as well as hybrid circuitry implementation using off-the-shelf components is also presented and validated by means of the network simulator Orcad Pspice.
Accelerating Internal Dimensions and Nonzero Positive Cosmological Constant

We present a new scenario for the moduli stabilization with a very small but nonzero positive cosmological constant $\lambda$. In this scenario the complex structure moduli are still stabilized by the three-form fluxes as in the usual flux compactifications, but the K$\ddot{\rm a}$hler modulus is not fixed by the KKLT scenario. In our case the scale factor of the internal dimensions is basically allowed to change with time. But at the supergravity level it is fixed by a set of dynamical (plus constraint) equations defined on the 4D spacetime, not by the nonperturbative corrections of KKLT. Also at the supergravity level it is shown that $\lambda$ is fine-tuned to zero, $\lambda =0$, by the same set of 4D equations. This result changes once we admit $\alpha^{\prime}$-corrections of the string theory. The fine-tuning $\lambda=0$ changes into $\lambda = \frac{2}{3} Q$, where $Q$ is a constant representing quantum corrections of the 6D action defined on the internal dimensions and its value is determined by the $\alpha^{\prime}$-corrections. It is also shown that this nonzero $\lambda$ must be positive and at the same time the internal dimensions must evolve with time almost at the same rate as the external dimensions in the case of nonzero $\lambda$.
Analysis of bed voidage characteristic of a gas-liquid-solid fluidized bed by CFD simulation and experiment

The bed expansion profile of a co-current three-phase fluidized bed have been studied using liquid as the continuous phase and gas as the discontinuous phase for different particle size and bed mass. Air, water and glass beads are used as the gas, liquid and solid phases respectively. The experiments were carried out in a 0.1m ID, 1.88m height vertical Plexiglas column. A two dimensional transient model has been developed to simulate the bed voidage behaviour of the mentioned gas–liquid–solid three-phase fluidized bed using the computational fluid dynamics (CFD) method. An Eulerian Granular Multiphase model has been used in the present study and simulations are carried out using the commercial CFD package Fluent 6.2. 16. The bed voidage is found to increase with the liquid velocity significantly, but the increase in bed voidage with gas velocity is meagre. The bed voidage is found to decrease with particle size and static bed height. The CFD simulation predictions are compared with the experimental data. The simulation results are in good agreement with the experimental values. Finally empirical correlations have been developed to predict bed voidage behaviour.
A Theoretical Analysis of Sound Localization, with Application to Amplitude Panning

Below 700Hz sound fields can be approximated well over a region of space that encloses the human head, using the acoustic pressure and gradient. With this representation convenient expressions are found for the resulting Interaural Time Difference (ITD) and Interaural Level Difference (ILD). This formulation facilitates the investigation of various head-related phenomena of natural and synthesised fields. As an example, perceived image direction is related to head direction and the sound field description. This result is then applied to a general amplitude panning system, and can be used to create images that are stable with respect to head direction.
Vibration Analysis of Partially Damaged Rotor Bar in Induction Motor under Different Load Condition Using DWT

The relevance of the development of monitoring systems for rotating machines is not only the ability to detect failures but also how early these failures can be detected. The purpose of this paper is to present an experimental study of partially damaged rotor bar in induction motor under different load conditions based on discrete wavelet transform analysis. The approach is based on the extraction of features from vibration signals at different level of damage and three mechanical load conditions. The proposed analysis is reliable for tracking the damage in rotor bar. The paper presents an analysis and extraction of vibration features for partially damaged rotor bar in induction motors. The experimental analysis shows the change in behavior of vibration due to load condition and progressive damage.
Using geographic information systems to predict (North Atlantic right whale (Eubalaena glacialis) habitat

Geographic Information Systems (GIS) are an innovative and powerful tool to define relationships between species and habitat in large marine ecosystems. The objectives of this study were: 1) to gather bathymetry, SST(sea-surface temperature), and right whale (Eubalaena glacialis) sightings data and convert them to GIS coverages, and 2) to create a GIS based logistic regression model to predict North Atlantic right whale (Eubalaena glacialis) distribution as a function of SST and bathymetry. Part of the Scotian Shelf, 45°00'N to 42°00'N latitude and 66°00'W to 61°00'W longitude, was used as a study area to develop the model. The validity of the model was tested in a separate area with known right whale distribution, and the results showed that the model predicted sightings where right whales had been observed. Observations had shown that during their seasonal migration, a portion of the population does not appear in the known summering grounds in the Gulf of Maine, Bay of Fundy, and on the Scotian Shelf. New genetic evidence suggested an additional summering ground. Using the model, predictions for the North Atlantic showed possible summering grounds in areas which were historical whaling grounds. The results from the model can be incorporated into the Recovery Plan for this species. GIS offers an inexpensive method to examine marine mammals in relation to environmental and oceanographic features which affect their life histories.
Charged Particle Trajectories in the Local Superbubble

In this thesis we study the propagation of cosmic rays (CR) emitted by sources in the Local Superbubble (LB). There are many bursting sources of CRs inside the LB which may be modelled as a continuous injection of CRs, and therefore we study the LB’s effect on CRs by calculating trajectories of individual protons from both a continuous and a bursting source within two models of the LB’s magnetic field. These models are constructed using information from literature, each having a regular and random component for which we assume equipartition of energy. We find that the escape time tesc(E) has a knee-like feature around E/Z = 5 ·1015 eV for coherence lengths of the random field smaller than the LB’s radius. Additionally, we find that tesc(E) ∝ E−α for energies E ≤ 2 ·1015 eV where α was calculated to be α = 0.354±0.008. The results are not entirely conclusive and we would have to run more simulations to validate that the knee-like feature stems from the bubble itself.
Two-Stage Fault Diagnosis Method Based on the Extension Theory for PV Power Systems

In order to shorten the maintenance time and make sure of the photovoltaic (PV) power generation system steadily in operation, a fault diagnosis system for photovoltaic power generation system was proposed in this paper. First, a PSIM software is used to simulate a 2.2 kW PV system, it can take the operating date of the PV system under different sunlight intensity and temperature conditions. In this paper, a two-stage diagnosis system based on the extension theory for PV power systems is proposed; the proposed method is not only be able to troubleshoot the system fault but also the damaged module can also be located. The primary strategy is to utilize the diagnosis array of daylight identification and to use light scanning of the damage array at night. Via wireless network the data is transmitted back to the diagnosis system for identifying the location of damaged module. The time and energy of manually locating the fault module can be greatly saved. Finally, the methods as proposed in this paper have been compared with other existing methods, by which to verify its superiority and usability.