Miracle-dz/UniFAR-FTUs huggingface dataset:
Research on Trajectory Tracking Control of Underwater Vehicle Manipulator System Based on Model-Free Adaptive Control Method

In order to improve the trajectory tracking accuracy of an Underwater Vehicle Manipulator System (UVMS) under uncertain disturbance conditions of ocean current, a Model-free Adaptive Control (MFAC) method was used. Combined with Radial Basis Function Neural Networks (RBFNN), the RBFNN-MFAC method is proposed to improve the performance of the controller. A hydrodynamic model of UVMS was defined in the commercial software, Fluent, to calculate hydrodynamics disturbance, and the mechanism of the dynamic model of UVMS was defined in the commercial software, Adams, to simulate the motion of UVMS. The trajectory tracking performance with various control schemes, including PID (Proportional Integral Derivative), MFAC and RBFNN-MFAC, were analyzed with the Adams and Simulink joint simulation model. The results show that the position tracking accuracy and the speed tracking accuracy with the MFAC control scheme were 68.1% and 81.0% better, respectively, than those with PID control scheme. The position tracking accuracy and the speed tracking accuracy with the RBFNN-MFAC control scheme were 66.3% and 43.1% better, respectively, than those with the MFAC control scheme. The MFAC control scheme and the RBFNN-MFAC control scheme proposed in this paper exhibit good trajectory tracking performance without the precise dynamic model of UVMS, which is of great importance to applications in engineering.
Spatiotemporal Variations of Evapotranspiration in Amazonia Using the Wavelet Phase Difference Analysis

The relationships and seasonal‐to‐annual variations among evapotranspiration (ET), precipitation (P), terrestrial water storage anomalies (TWSA), radiation (downward shortwave radiation, DSR), and phenology (leaf area index, LAI) are complex across the Amazon basin. To analyze how ET is controlled by these influencing factors, we used wavelet phase difference (WPD) to investigate the effects of P, TWSA, DSR, and LAI on ET at different spatiotemporal scales. The Amazon‐scale averaged ET has strong correlations with these factors at the annual and multi‐year periodicities. The patterns of WPDs have south‐north and west‐east divides due to the significant variation in climatic conditions. The results demonstrate that ET is mainly affected by water and energy availability while vegetation regulates both processes. The deep soil moisture/groundwater can provide strong subsidies to ET during the meteorological dry season in the water‐limited area of Amazon. The WPD can well reflect the responses of ET to the variations of P, TWSA, DSR, and LAI, and the process of vegetation sustaining ET in the dry years in the water‐limited area of the Amazon.
Efficacy of Ultrasound-Guided Percutaneous Lavage and Biocompatible Electrical Neurostimulation, in Calcific Rotator Cuff Tendinopathy and Shoulder Pain, A Prospective Pilot Study

Calcific tendinopathy of the shoulder (CTS) is the most common cause of shoulder pain. Conservative treatment is considered as the first therapeutic choice for CTS. The main objective of this study was to assess the effect of US-guided needling (UGN) compared to UGN plus Biocompatible Electrical Neurostimulation (BEN) in the treatment of the CTS. Pilot, prospective, non-interventional, monocentric, and observational study of patients treated for calcific rotator cuff tendinopathy and shoulder pain. Patients’ selection, enrollment and interventions were conducted at the Chiparo Physical Medicine and Rehabilitation outpatient facility. Forty adult patients (aged 40–60 years) with a diagnosis of CTS in the acute and colliquative phase were recruited and enrolled into the study. Participants were assessed for self-perceived pain through the Numerical Rating Scale (NRS), and for functional limitation through the Shoulder Pain and Disability Index score (SPADI) at baseline (T0), after 15 days (T1), and after 40 days (T2). As a possible confounding factor between the two treatments’ response, the dimension of the tendon calcification was also assessed by US-examination. Through the study, both groups improved their perceived functional performance of the arm (p-value < 0.001). AT T1, the SPADI score decreased by half in both groups, and the improvement remained stable at T2. A multiplicative effect (Time × Treatment) was demonstrated (p-value < 0.001). An improvement in the NRS score was measured at T1, and it remained stable at T2, a multiplicative effect was also reported (p-value < 0.001). The main results of this pilot study provide evidence that UGN plus BEN increases functional performance and reduces shoulder pain in individuals with CTS. Moreover, the tendon calcification dimension at the baseline and the percentage of drainage of the lesion were associated with a functional performance recovery and pain reduction detected after intervention.
Yield Performance of Calocybe indica on Different Agricultural Subatrate

The Milky mushroom, Calocybe Indica was cultivated on different agricultural substrate, paddy straw, wheat straw, sugarcane trace and mango dry leaves. The spawning was done by sterilization of all the four substrate. The bags were kept in mushroom growing room with the maintenance of temperature and humidity 30 c-35 c and 70-80 % respectively. The minimum days requires for completion of spawn run (18.4 days), primordial formation (25.2 days) and days for first harvest (32.4 days) was first observed on cultivation with Paddy straw. The maximum yield on fresh weight basis and biological efficiency (134.86 %) was also found to be as the same treatment with the Paddy straw as a substrate. The biological efficiency of wheat straw was at par with Sugarcane trace as substrate which was 85.07 % and 85.02 % respectively.
Power optimization of Low Noise Amplifier (LNA) and DAC used in Closed Loop Deep Brain Neuro-Stimulator (CDBS) at 45nm using Cadence Virtuoso

Deep-Brain-Stimulation (DBS) is a rapidly growing area which aims to enhance the lives of patients with different types of brain disorders. In regards of implanted devices, it's perhaps one of the most active research topics. This study describes a Low-Noise-Amplifier (LNA) and Digital-to-Analog Convertor (DAC) for biopotential collection on Deep Brain Stimulation.
STUDY OF CRUSTAL STRUCTURE OF THE FLORES ISLAND USING RECEIVER FUNCTION METHOD

Flores is an island located in the north of the East Nusa Tenggara region. Formed as a consequence of very complex tectonic setting that might cause relatively high level of seismic in the region. This study aims to characterize the crust structure based on the S wave velocity model, the Vp/Vs ratio, and crustal thickness beneath the station on Flores Island. This study was using receiver function analysis method of teleseismic earthquake data with magnitude criteria ≥ 6 and epicenter distance 30⁰-90⁰. Seismic signal recorded on broadband stations three components. This study was using LBFI station. Velocity model of S wave and Vp/Vs ratio determined by using the non-linear Neighbourhood Algorithm (NA) inversion. Furthermore, the velocity and Vp/Vs ratio models will be used to obtain the depth of the migration process of the amplitude of the receiver function to depth. From the results of processing the depth of the Moho layer on the island of Flores under the LBFI station was identified as 41 km. The existence of the slab can be identified quite well that is at depth about 110 to 140 km.
New material systems for third generation infrared detectors

Third-generation infrared (IR) systems are being developed nowadays. In this class of detectors, two main competitors, HgCdTe photodiodes and quantum-well IR photoconductors (QWIPs), are included. Recently, two new material systems have been emerged as the candidates for third generation IR detectors, type II InAs/GaInSb strain layer superlattices (SLSs) and quantum dot IR photodetectors (QDIPs). In the paper, issue associated with the development and exploitation of multispectral photodetectors from these new materials is discussed. Discussions is focused on most recently on-going detector technology efforts in fabrication both photodetectors and focal plane arrays (FPAs). The challenges facing multicolour devices concerning complicated device structures, multilayer material growth, and device fabrication are described.
Ride Comfort Analysis of Passenger Vehicle Featuring ER Damper with Different Tire Pressure

In this work, performance analysis to improve ride comfort of an ER (electrorheological) fluid damper for a mid-sized passenger vehicle in terms of tire pressure is presented. An ER damper by considering specification for a mid-sized commercial passenger vehicle is proposed and mechanically designed. After manufacturing and assembling the proposed ER damper with design parameters, their performance such as field-dependent damping forces are experimentally measured. A quarter-vehicle ER ECS (Electronic Control Suspension) system consisting of the ER damper, sprung mass, spring, sky-hook controller and tire is constructed to analysis the ride comfort performances. Vertical tire stiffness with different tire pressure is experimentally measured and investigated. In addition, ride comfort analysis such as vertical acceleration root mean square (RMS) of sprung mass is investigated under bump road using quarter-vehicle test equipment.
Astragalus Polysaccharides/PVA Nanofiber Membranes Containing Astragaloside IV-Loaded Liposomes and Their Potential Use for Wound Healing

Delayed wound healing is a common and serious complication in diabetic patients, especially the slow healing of foot ulcers, which seriously affects the quality of life of patients and is also the most important risk factor for lower limb amputation. The multifunctional novel dressing prepared by loading the polymer nanofibers with anti-inflammatory and prohealing plant extracts can promote the wound repair of these ulcers by electrospinning technology. Liposomes are nanoparticles prepared from phospholipids and have been widely used as drug delivery systems. Liposomes can be combined with electrospun nanofibrous webs to facilitate local and sustained delivery of loaded bioactive substances. In this study, liposomes were prepared with astragaloside IV (AS) by employing a modified ethanol injection method and conducting the physical and chemical characterization (e.g., the particle size, polydispersity index, zeta potential, and entrapment efficiency). Astragalus polysaccharides were extracted from Astragalus membranaceus. Subsequently, we prepared the electrospun polyvinyl alcohol (PVA)/astragalus polysaccharide (APS)/astragaloside IV (AS) nanofibers. The morphology of the produced ASL/APS/PVA, APS/PVA, and PVA nanofibers were analyzed by scanning electron microscopy (SEM), and it turns out that the addition of astragalus extract made the fiber diameter smaller and the fibers arranged neatly with no dripping. An induced diabetic rat model was built, and a diabetic ulcer model was built by total cortical resection to assess the prorepair ability of the prepared nanofibers. According to in vivo animal experiments, the nanofibrous membrane loaded with APS and ASL was reported to inhibit the occurrence of wound inflammation, enhance the deposition of collagen fibers (P < 0.05) and the repair of regenerated epithelium (P < 0.05), and effectively strengthen the wound healing of diabetic rats (P < 0.05). In brief, PVA-loaded APS/ASL nanofibrous membranes refer to a prominent wound healing dressing material, which can effectively facilitate the healing of diabetic wounds, and they are demonstrated to be highly promising for application in diabetic wound dressings and tissue engineering.
The Impact of Developmental HR Practices on Career Self-Management and Organizational Citizenship Behavior: A Moderated Mediation Model

Purpose Drawing on the social exchange and signal theory, this study aims to investigate the impact of developmental HR practices on employees’ career self-management and organizational citizenship behavior (OCB) through the mediating role of direct supervisor’s transformational leadership and the moderating role of perceived organizational support. Methods Data were congregated from 571 employees belonging to a diverse range of organizations in southwest China. Statistical procedures, such as hierarchical regression and bootstrapping analysis based on Hayes’ PROCESS on SPSS 23, were conducted to test the hypotheses. For model fitness, we used AMOS V 22. Results A positive effect of developmental HR practices on employees’ career self-management and OCB was found, which was partially mediated by direct supervisor’s transformational leadership. Moreover, perceived organizational support is anticipated to moderate the indirect relationship among developmental HR practices, career self-management and OCB through supervisor’s transformational leadership. Discussion This study finds that employees’ perceived organizational support should be given more attention by organizations, especially in the context of transformational direct supervisors implementing developmental HR practices. Meanwhile, this study extends the utility of the concept of developmental HR practices to the leadership and career management literature.
Problem Based Teaching And Learning In An Introductory Level Lean Manufacturing Systems Course

Problem based learning (PBL) is a widely used technique in the development of technical curriculum delivery (Putnam, 2001) 18 . In the design and development of an introductory level lean manufacturing course taught at Purdue University, a PBL approach was utilized. The approach allowed the instructor to expose students to a manufacturing strategy that has been adopted by manufacturers world-wide. Immersing students in the context of lean manufacturing strategies required a combination of manufacturing facility tours and simulation type exercises in lab. This made the class more challenging, motivating, and enjoyable, while allowing students to acquire the basic knowledge and skills needed by industry. Class evaluations, collected over four semesters, reveal that PBL is a strong approach to teaching an introductory level lean manufacturing course.
Functional Safety Analysis and Design of Sensors in Robot Joint Drive System

The reliable operation of the sensors of robot joint drive systems (RJDs) is a key factor in ensuring the safety of equipment and personnel. Over the years, additional safety-related systems have been designed to prevent safety incidents caused by robot failures, ignoring the functional safety issues of the robot sensors themselves. In view of this, based on IEC61508, a functional safety analysis and design method for sensors of RJDs is proposed in this paper. Firstly, the hazard analysis and risk assessment clarified the goals that the safety protection function of the RJD’s sensor should achieve. Then, by establishing the motor drive model and transmission model, a model-based sensor fault diagnosis and isolation strategy is proposed. Considering the fault-tolerant operation of system, a fail-operational hardware architecture of the safety-related system is designed. Markov analysis shows that the safety integrity level (SIL) of safety-related systems can reach SIL3. Finally, experiments are designed to validate the proposed fault diagnosis and fault tolerance strategy. The results show that the safety-related system can effectively locate sensor failures, realize fault-tolerant control when a single sensor fails and perform safe torque off (STO) protection when multiple sensors fail.
Clinical and molecular characteristics of acute myeloid leukemia with MPL mutation

ABSTRACT Objectives The current study aimed to explore the incidence of MPL mutations and the clinical and molecular characteristics of AML with MPL mutation. Methods In total, 1509 patients with newly diagnosed AML were retrospectively analyzed between January 2017 and December 2020. MPL mutations were detected via next-generation sequencing. During the same period, we also enrolled 30 patients with other myeloid neoplasms (MNs) with MPL mutation, which included myelodysplastic syndrome (n = 15), myelodysplastic syndrome/myeloproliferative neoplasm (MDS/MPN) (n = 6), and MPN (n = 9). The clinical characteristics of MPL-mutated AML and other types of MNs or MPL-wide type (MPL-wt) AML were compared, and the spectrum of co-mutations and MPL mutation profiles in MPL-mutated AML were analyzed. Results MPL mutations were identified in 19 (1.26%) of 1509 patients with AML. The waterfall diagram showed that the co-mutations were mainly epigenetic modifications (TET2, IDH1, and EZH2), spliceosomes (SRSF2), and transcription factors (RUNX1). The platelet count of the AML group was significantly lower than that of the MPN group (p = 0.001). MPL mutations were commonly observed in the intracellular region in AML but the transmembrane region in MPN (p = 0.013). The MPL-mutated AML group had a lower white blood cell count and a lower rate of complete remission than the MPL wild-type AML group (p = 0.037). Conclusion MPL mutations are clinically relevant in patients with AML, and they may be a novel subtype characterized by lower white blood cell counts and poor complete remission rates. However, further studies must be conducted to identify its correlated mechanism.
Identification and Characterization of a Novel Type of Cartilage Stem/ Progenitor Cells from Tibetan Mastiff

Based on the physiologically non-self-renewing property of articular cartilage, the treatment of articular cartilage lesions remains an important challenge. Articular cartilage, the target of osteoarthritis (OA), contains renewable cartilage stem/progenitor cells (CSPCs) to maintain the tissue homeostasis. Compared with other adult stem cells, the self-renewal capacity and preference for chondrogenesis of resident CSPCs have propelled their exciting therapeutic prospects for cartilage repair. Tibetan mastiff, the ancestor of large breed dogs worldwide, represents a valuable model for human diseases. To our knowledge, this is the first study to capture the emergence of Tibetan mastiff-derived CSPCs. Our study aimed to unveil the biological properties and differentiation multipotency of CSPCs. CSPCs were characterized by the clonogenicity, growth curves and karyotype analysis, respectively. The results showed that the CSPCs of Tibetan mastiff displayed self-renewal ability, proliferative potential, and hereditary stability. Moreover, the CSPCs of Tibetan mastiff also positively expressed recognized surface antigens of human CSPCs. Additionally, CSPCs exhibited differentiation multipotency, including osteogenic, adipogenic and chondrogenic potential in vitro . These findings may propell CSPCs application in a clinical study, suggesting potential therapeutic treatment for OA or related joint diseases.
miRNA Pattern in Hypoxic Microenvironment of Kidney Cancer—Role of PTEN

MicroRNAs are post-transcriptional regulators of gene expression, and disturbances of their expression are the basis of many pathological states, including cancers. The miRNA pattern in the context of tumor microenvironment explains mechanisms related to cancer progression and provides a potential target of modern therapies. Here we show the miRNA pattern in renal cancer focusing on hypoxia as a characteristic feature of the tumor microenvironment and dysregulation of PTEN, being a major tumor suppressor. Methods comprised the CRSPR/Cas9 mediated PTEN knockout in the Renca kidney cancer cell line and global miRNA expression analysis in both in vivo and in vitro (in normoxic and hypoxic conditions). The results were validated on human cancer models with distinct PTEN status. The increase in miR-210-3p in hypoxia was universal; however, the hypoxia-induced decrease in PTEN was associated with an increase in miR-221-3p, the loss of PTEN affected the response to hypoxia differently by decreasing miR-10b-5p and increasing miR-206-3p. In turn, the complete loss of PTEN induces miR-155-5p, miR-100-5p. Upregulation of miR-342-3p in knockout PTEN occurred in the context of the whole tumor microenvironment. Thus, effective identification of miRNA patterns in cancers must consider the specificity of the tumor microenvironment together with the mutations of key suppressors.
Sleep Position Detection with a Wireless Audio-Motion Sensor—A Validation Study

It is well documented that body position significantly affects breathing indices during sleep in patients with obstructive sleep apnea. They usually worsen while changing from a non-supine to a supine position. Therefore, body position should be an accurately measured and credible parameter in all types of sleep studies. The aim of this study was to specify the accuracy of a neck-based monitoring device (Clebre, Olsztyn, Poland) mounted at the suprasternal notch, in determining a supine and non-supine sleeping position, as well as specific body positions during sleep, in comparison to polysomnography (PSG). A sleep study (PSG along with a neck-based audio-motion sensor) was performed on 89 consecutive patients. The accuracy in determining supine and non-supine positions was 96.9%±3.9% and 97.0%±3.6%, respectively. For lateral positions, the accuracy was 98.6%±2% and 97.4%±4.5% for the right and left side, respectively. The prone position was detected with an accuracy of 97.3%±5.6%. The study showed a high accuracy in detecting supine, as well as other gross positions, during sleep based on a sensor attached to the suprasternal notch, compared to the PSG study. We feel that the suprasternal notch is a promising area for placing wireless sleep study devices.
Investigating the Failure Mode during Crack Propagation Using Image Analyses

The purpose of this paper is to investigate the fracture modes of the crack propagation of fourteen sandstone samples under Cracked Chevron Notch Brazilian Disc (CCNBD) test conditions through the use of image analysis and the high speed camera. The fracture mode is characterized by the displacement of 0.5mm glass beads placed on the sandstone surface relative to the approximate orientation of the fracture propagation. Using a Phantom v2011 High Speed Camera the fracture generation and propagation of the samples are recorded and processed for image analysis. ImageJ with Multi-Tracker and Manual Tracker, as well MATLAB® software were used to analyze the movement of particles during fracture propagation. It was found that the ImageJ software was able to track the movement of the particles and the output of the MATLAB® script was able to plot vector trajectories of the particles. For the analysis of samples tested under different orientations it was found that both shear mode and mixed-mode were evident in the fracture propagation.
Performance Evaluation of Propeller for High Altitude by using Experiment and Computational Analysis

Wind tunnel experiment and computational analysis have been carried out to evaluate the performance of propeller for scale electric-powered HALE UAV, named EAV-2H+. Performance curves are measured for three propellers and their adequacy for EAV-2H+ installation is examined through consideration of operating conditions. Decline in performance coefficients is observed in low rpm region. Also, the effect of transition tape on propeller performance is measured and analyzed. The computational performance analyses are carried out by using commercial CFD program. The thrust and power coefficient from computations show good agreement with experimental results. Performance coefficients are compared and the influence of measurement device which contributes to discrepancy of the results is examined. Transition SST model is confirmed to yield the tendency of performance decline in low rpm range, similar to experimental observation. The decrease in aerodynamic performance of blade element due to low Reynolds number is identified to cause the decline in propeller performance. Analyses for high altitude conditions confirms degradation in propeller performance.