Miracle-dz/UniFAR-FTUs huggingface dataset:
Practical Implementations of Advanced Process Control for Linear Systems

: Most advanced process control systems are based on Model Predictive Control (MPC). In this paper we discuss three critical issues for the practical implementation of linear MPC for process control applications. The ﬁrst issue is related to oﬀset free control and disturbance models; the second issue is related to the use of soft output constraints in MPC; and the third issue is related to the computationally eﬃcient solution of the quadratic program in the dynamic regulator of the MPC. We have implemented MPC in . Net using C# and the MPCMath library. The implemented MPC is based on the target-regulator structure. It enables oﬀset free control; it can be computed eﬃciently on-line using several optimization algorithms; and accommodates soft constraint for the outputs and for shaping the set-point tracking penalty function. We report selected observations using this implementation and discuss their practical implications for process control. If the control and evaluation intervals are chosen too short, the predicted behaviour of the controllers may have unstable characteristics. Depending of the degrees of freedom, oﬀset-free control of a number of the controlled variables can be achieved by introduction of noise models and integration of the innovation errors. If the disturbances increases, oﬀset-free control cannot be achieved without violation of process constraints. A target calculation function is used to calculate the optimal achievable target for the process. The use of soft constraints for process output constraints in the MPC controllers, ensures feasible solutions. The computational load as function of controllers type, model dimension and constraint type are shown.
ANTI-TUMOR EFFECT OF CACTUS POLYSACCHARIDES ON LUNG SQUAMOUS CARCINOMA CELLS (SK-MES-1)

Background: Cactus polysaccharides are the active components of Opuntia dillenii which have been used extensively in folk medicine. In this study, we investigate the anti-tumor effect of cactus polysaccharides on lung squamous carcinoma cells SK-MES-1. Materials and Methods: The inhibitory effect of Cactus polysaccharides on lung squamous carcinoma cells were detected by MTT assay. Cell cycle was determined by flow cytometry and cell apoptosis was determined by AnnexinV assay. Western-blotting was applied to detect P53 and PTEN protein expression in the cells treated with cactus polysaccharides. Results: Results showed that different concentrations of wild cactus polysaccharides prevent SK-MES-1 cells growth and induces S phase arrest. The data also revealed that cactus polysaccharides cause apoptosis in SK-MES-1 cells determined by Annexin-V assay. Furthermore, cactus polysaccharides induced growth arrest and apoptosis may be due to the increase of P53 and phosphatase and tension homolog deleted on chromosome ten (PTEN) protein. Conclusion: Cactus polysaccharides have anti-tumor activity on lung squamous carcinoma cells. MTT:3-(4, 5-Dimethylthiazol-2-yl)-2, 5-diphenyltetrazolium bromide ; PBS: Phosphate buffered saline ; DMSO:Dimethyl sulfoxide ; PI: Propidium iodide. The inhibiting effect of cactus polysaccharides on the lung squamous carcinoma cells was detected by MTT assay for 24h and 48h. Cactus polysaccharides significantly inhibited cellular proliferation of the lung squamous carcinoma cells. The results showed that the inhibited rate of SK-MES-1 cells treated with cactus polysaccharides in a concentration and time dependent manner (P <0.01) (Fig. 1). a steady in Our data showed that the cactus polysaccharides inhibited proliferation of lung squamous carcinoma SK-MES-1 cells through inducing S phase arrest and triggering apoptosis. Insight into molecular mechanisms indicated that the cactus polysaccharides could significantly increased P53 and PTEN expression, which were negatively regulated cell cycle and induced apoptosis in the lung cancer cells. In conclusion, our study is the first one to identify anti-tumor affects of cactus polysaccharides on lung squamous carcinoma cells. Our data generate evidences for further evaluation of cactus polysaccharides as a new drug for lung cancer. The molecular mechanisms of wild cactus polysaccharides preventing cell proliferation need further investigation.
KERATINIZED ATTACHED GINGIVA AROUND DENTAL IMPLANTS: THE ROLE, STRUCTURE, INCREASING TECHNIQUES

: This study includes review of scientific literature about modern concept of keratinized attached gingiva increasing around implants. It covers experimental and clinical cases, studied the relationship between the presence of the gingiva and tissue condition, surrounding the implants. Also, keratinized tissue increasing methods, with collagen matrix usage, was described.
Are Ligands for NK Cell Ig-like Receptors HLA-F and MHC Class I Open Conformers

Killer Ig-like receptors (KIRs) are innate immune receptors expressed by NK and T cells classically associated with the detection of missing self through loss of their respective MHC ligand. Some KIR speciﬁcities for allelic classical class I MHC (MHC-I) have been described, whereas other KIR receptor–ligand relationships, including those associated with nonclassical MHC-I, have yet to be clearly deﬁned. We report in this article that KIR3DL2 and KIR2DS4 and the nonclassical Ag HLA-F, expressed as a free form devoid of peptide, physically and functionally interact. These interactions extend to include classical MHC-I open conformers as ligands, deﬁning new relationships between KIR receptors and MHC-I. The data collectively suggest a broader, previously unrecognized interaction between MHC-I open conformers—including prototypical HLA-F—and KIR receptors, acting in an immunoregulatory capacity centered on the inﬂammatory response. The Journal of Immunology , 2013, 191: 000–000.
A Novel Procedure for Virtual Measurements Generation suitable for Training and Testing in the context of Non Intrusive Load Monitoring

— Getting "smarter" Energy by means of advanced electrical and computer engineering tools is the theme of our digital age. This paper presents a new concept for virtual data generation in the context of non-intrusive load monitoring, where the goal is to fill in the gap when aggregate measurements are needed along with individuals ones. We develop a method to generate aggregate measurements starting from single original measurements. The performance of standard NILM tools and algorithms on both original and "virtual" data is compared using own lab measurements.
Fatty Acids Induced by Arachidonic Acid and Other Free Mitochondrial Dysfunction during Apoptosis Evidence against Calcium as a Mediator of

2 Apoptosis is often accompanied by activation of phospholipase A 2 , causing release of free fatty acids (FFAs), which in turn are thought to contribute to the loss of mitochondrial transmembrane potential ( (cid:1)(cid:2) m ). In these experiments, we asked whether calcium plays a role as an intermediate in this process. A total of 14 FFAs were compared for their ability to cause loss of (cid:1)(cid:2) m and for their ability to affect levels of intracellular calcium. Among the FFAs, unsaturated FFAs tended to induce apoptosis while saturated FFAs did not. Arachidonic acid (AA) was most damaging, causing loss of (cid:1)(cid:2) m and cell death in 8–10 h while linoleic acid, (cid:3) -linolenic acid, and docosapentaenoic also strongly induced apoptosis. Effects of the FFAs on levels of intracellular calcium were very different. Many caused strong calcium responses; however, the ability to induce a strong calcium response was not predictive of ability to induce apoptosis, and overall, we did not ﬁnd a correlation between apoptosis and calcium induction. Also, verapamil and TMB-8 were able to block the calcium response, but these inhibitors did not prevent loss of (cid:1)(cid:2) m , indicating that the calcium response is not necessary for FFA-induced loss of (cid:1)(cid:2) m . In contrast, we found that cyclosporine A could inhibit the AA-induced loss of (cid:1)(cid:2) m with both whole cells and isolated mitochondria, conﬁrming that the antimitochondrial effects of FFA can stem from direct effects on the mitochondrial permeability transition pore. Finally, we show that the strong apoptosis-inducing activity of AA may stem from its ability to selectively induce its own release. The Journal of Immunology, 2006, 177: 6398–6404.
Institutional Knowledge at Singapore Management University MIDAS: Empowering 802.11ac with multiple-input distributed antenna systems

Next generation WLANs (802.11ac) are undergoing a major shift in their communication paradigm with the introduction of multi-user MIMO (MU-MIMO), transitioning from single-user to multi-user communications. We argue that the conventional AP deployment model of co-located antennas as well as their PHY and MAC mechanisms are not designed to realize the complete potential of MU-MIMO. We propose to leverage distributed antenna systems (DAS) to empower next generation 802.11ac networks. We highlight the multitude of beneﬁts that DAS brings to MU-MIMO and 802.11ac in general. However, several challenges arise in the process of realizing these beneﬁts in practice, where avoiding client modiﬁcations and making only minimal software modiﬁcations to APs is important to enable rapid adoption. Towards addressing these challenges, we present the design and implementation of MIDAS , the Multiple-Input Distributed Antenna System . MIDAS couples a DAS deployment of AP antennas with a suite of novel yet standards-compatible mechanisms at the PHY and MAC layers that best leverage the DAS deployment to maximize 802.11ac performance. Our WARP-based experimental evaluation demonstrates MIDAS’s ability to signiﬁcantly boost the performance of current 802.11ac design, demon-strating throughput gains over 802.11ac MU-MIMO for 100-200%, while remaining amenable to commercial adoption.
Mental Health Treatment Utilization in OIF/OEF National Guard and Reserve Troops With and Without DSM Diagnoses

Mental health treatment utilization in OIF/OEF National Guard and Reserve troops with and without DSM diagnoses. Military service members have an increased risk of developing mental health (MH) problems following deployment to Iraq or Afghanistan, yet only a small percentage seek mental health treatment. The aim of the present study was to explore patterns of MH service utilization within the first 12 months following return from combat deployment. Participants were 169 service members who had returned from war-zone deployment in either Iraq or Afghanistan and had assessments covering a 12-month period following their homecoming. The authors first examined the prevalence of mental health diagnoses and engagement with mental health treatment (e.g., visits to the emergency room, inpatient hospitalization, individual therapy, group therapy, family or couple therapy, medication appointments, and self-help). Regression analyses explored whether distress, functioning, diagnoses, or social support predicted treatment use. Findings indicated that 28 of 50 military service members (56%) who met diagnostic criteria for a mental health disorder accessed services in the year following their return from deployment. Individual treatment was the most common modality, and those with major depressive disorder (MDD) reported the most treatment contacts. Social support was not associated with use of mental health services. Baseline functioning and psychiatric distress predicted entry into treatment whereas only psychiatric distress predicted amount of mental health service use in the 12-month postdeployment period. Findings highlight the need for enhanced strategies to link those reporting psychiatric distress with MH treatment services and increase community connected-ness regardless of whether they meet full criteria for a mental health diagnosis. personal resilience. Preliminary research has demonstrated the utility of such brief, collaborative contacts in increasing interest in engaging in mental health treatment in both face-to-face (Stecker et al., 2011) and telephone (Seal et al., 2012) modal-ities. In sum, future intervention efforts should focus on treatment entry and retention within VAMC systems with particular focus on early screening for psychiatric distress and use of stigma reduction interventions to keep service members en-gaged in treatment.
Stressing factors in nurses who work in the sector of urgency and emergency

— Currently, stress is considered one of the main health problems that has been gaining importance, due to the proportion of its impact on people's lives. The objective of the research was to verify the main stress factors among nurses in the urgency and emergency sector and their influence on nursing care. Methodology: qualitative-quantitative, descriptive, cross-sectional field research, whose sample consisted of 30 nurses. For data collection, a form prepared by the researchers was used, containing questions about sociodemographic and occupational characteristics of nurses, open questions to verify the influence of stress on nursing care, and to investigate the main stressors in nurses, an instrument was used. adapted from the “Nurses Stress Inventory”. Results: the research revealed that situations that generate stress are mainly associated with the lack of human resources (90%) and materials (80%), both pointed out by nurses as being often or always stressful factors. These factors and the work overload combined with the professional's unpreparedness are recognized by most nurses as a negative influence on work and on the care provided to the patient. Conclusion: the results indicate that nurses working in the urgency and emergency sector are exposed to stressful situations that can compromise the care provided to the client. The identification of these stressors is essential for the development of strategies that alleviate the stressors, providing better working conditions, humanization and safety in health care. chave— Estresse, Enfermagem, Urgência e emergência.
External factors affecting perceived usability: A closer look at the effect of emotion prior to interaction

: Usability is the extent to which a product is effective, efficient, and satisfying in a particular context. Usability assessment can be important for the development of successful products as it evaluates the way the products satisfy the user needs. As emotions are part of cognition, it is reasonable to think they may influence the human interaction with products, affecting the perceived usability . Based on this premise, multiple researchers have proposed models for product appraisal considering objective usability in terms of effectiveness and efficiency and subjective aspects such as the emotion involved. However, these approaches do not include external factors such as skill level, individual preferences and affective states; yet, these external factors may affect the perception of usability. This research work explores the effects of external factors in the perceived usability of products, and specifically focuses on the effect of emotions experienced just before interaction with a product. Data from a preliminary study on the effect of emotional states in perceived usability is presented. The results showed that when positive emotion exists, the perceived usability is significantly higher than the one perceived in the presence of negative emotion.
Design and Implementation of Instrumentation Amplifier for EEG in 180nm CMOS technology

— The EEG is Electro Encephalo Gram that which gives the electrical activity of the brain. Analysis of the electrical activity is very important to diagnose neurological problems. But, the problem generally involved is that the EEG signals have very low amplitude and these very low amplitude signals cannot drive displays for further analysis. So, we require to use amplifiers. Instrumentation amplifier is widely used for such applications because they give high gain. For designing the instrumentation amplifier, we have to first design the operational amplifier and this is further used to design the instrumentation amplifier. The 180nm CMOS technology has been used for the Implementation of this amplifier. It gives a hiah gain of 111 dB an low power dissipation of 16mW.
a-COMPACT VALUED MULTIFONCTIONS

In this paper we give two applications of results of Shchegolkov and Saint-Raymond on Borel sets with o-compact sections. First we give a sufficient condition under which a partition of a Polish space into o-compact sets admits a Borel cross-section. Then a representation theorem for o-compact valued multifunctions, expressing them as unions of continuously indexed Borel graphs, is proved.
New Generation Focused Crawler

: Vertical search engines use focused crawlers as their key component and develops some specific algorithms to select web pages relevant to some pre-defined set of topics. Therefore, to effectively build up a semantic pattern for specific topics it is extremely important for such search engines. Crawlers are software which can traverse the internet and retrieve web pages by hyperlinks. A focused crawler traverses the web selecting out relevant pages to a predefined topic and neglecting those out for prioritizing the URL queue. While surfing the internet it is difficult to deal with method that analyzes the reference-information among the pages, relevant pages and to predict which links lead to quality pages. In our proposed work we calculate the link score based on page rank and average relevancy score of parent pages (because we know that the parent page is always related to child page which means that for detailed information any author prefers the child page). After finding out the link score, we compare the link score with some threshold value. If link score is greater than or equal to threshold value, then it is relevant link. Otherwise, it is discarded. Focused crawler first fetches that link which has greater value compared to all link scores and
Running Head: MEAT-EATING AND COGNITIVE DISSONANCE Meat-Eating, Cognitive Dissonance and Gender Differences

Previous studies have found that exposing meat-eaters to the meat-animal connection can induce cognitive dissonance. However, these studies have only used lamb as the stimulus for the meat-animal connection, and it is unclear whether the results are reproduceable with other animals. Furthermore, consistent gender differences in dissonance have been observed, and there has been little investigation into the possible mechanisms behind them. The present study aimed to reproduce previous findings using a chicken stimulus, to explore empathy and gender role orientation as possible mechanisms for gender differences in dissonance, and to further investigate justifications for eating meat. Recruited meat-eaters (n = 235) were randomly assigned to three conditions: lamb, chicken and control. Those in the lamb and chicken conditions were exposed to the meat-animal connection by reading about the processing of an Australian meat lamb or chicken. Those in the control read about apples. All participants completed a preand post-condition affect measure with dissonance-related emotions. A positive difference between preand post-condition affect was indicative of cognitive dissonance. Results indicated that, on average, participants in the lamb and chicken conditions experienced greater dissonance than those in the control, indicating that exposure to the meatanimal connection induced dissonance. However, when analysed by gender, an average dissonance effect was found only in women. Small associations were found between cognitive dissonance, empathy and gender role orientation. Justifications for eating meat were also analysed. Implications are discussed.
Eating disorders - anorexia as an interdisciplinary problem

The etiology of this disorder is multifactorial and unclear. The predisposing factors include: genetic factors, personality disorders, specific family patterns (overprotection, avoiding conflicts) and high economic status. Diagnosis of AN is a challenge. Symptomatology is variable, including: behavior changes, psychological and somatic symptoms, specific biochemical and hormonal abnormalities. A treatment is multidisciplinary and multi-stage, comprising: (1) the life saving therapy (prevention of dehydration, electrolyte imbalance and cachexia), (2) restoration of normal body weight, (3) adjuvant pharmacotherapy, (4) psychotherapy. The efficacy of treatment is unsatisfactory. Anorexia has the highest mortality rate of all mental disorders: after 15-20 years the mortality prevalence rate is 19-20%, mainly as a result of cardiovascular complications and suicides.
Carga de enfermedad por tabaquismo e impacto potencial del incremento de precios de cigarrillos en el Perú

Objectives. To calculate the burden of smoking-related disease and evaluate the potential economic and health impact of tax-induced cigarette price increase in Peru. Materials and methods. A microsimulation model was used to estimate smoking-attributable impact on mortality, quality of life, and costs associated with heart and cerebrovascular disease, chronic obstructive pulmonary disease, pneumonia, lung cancer, and another nine cancers. Three scenarios, involving increased taxes, were evaluated. Results. A yearly total of 16,719 deaths, 6,926 cancer diagnoses, 7,936 strokes, and 7,548 hospital admissions due to cardiovascular disease can be attributed to smoking in Peru. Similarly, 396,069 years of life are lost each year from premature death and disability, and the cost of treating smoking-attributable health issues rises to 2,500 million soles (PEN 2015). Currently, taxes on tobacco cover only 9.1% of this expense. If cigarette prices were to increase by 50% over the next 10 years, 13,391 deaths, 6,210 cardiovascular events, and 5,361 new cancers could be prevented, representing an economic benefit of 3,145 million (PEN) in savings in health costs and increases in tax revenues. Conclusions. Smoking-attributable burden of disease and costs to the health system are very high in Peru. Higher cigarette taxes could have substantial health and economic benefits for the country.
The Combined Anti-in ammatory Strategy of Beta-2 Adrenergic Agonist and Glucocorticoid on the Laying Hen Model of Ovarian Cancer: the Immune Traits and Ovarian In ammatory Functions

Ali Hate (  hate .ali@gmail.com ) University of Tehran https://orcid.org/0000-0002-2173-9862 Ahmad Zare Shahneh University of Tehran Zarbakht Ansari Pirsaraie Sari Agricultural Sciences and Natural Resources University Ali Mohammad Alizadeh Tehran University of Medical Sciences Mohammad Pouya Atashnak Simon Fraser University Reza Masoudi Animal Science Research Institute (ASRI) Frederic Pio Simon Fraser University
Monovalent Copper and Silver Ions Block DNA Polymerase Chain Reaction

In the present study we present the dramatic effect that monovalent copper ions (Cu(I))have on the DNA polymerase chain reaction, and the moderate effect which monovalent silver ions (Ag(I)) have on it. Our research utilizes the commercial Polymerase Chain Reaction (PCR) system: in anaerobic conditions, in the presence of less than 0.1  M of Cu(I) ions or in the presence of less than 10  M of Ag(I) the 11 PCR system was entirely down. 12 Under the same conditions, 1  M of divalent copper ions (Cu(II)) ions only a 13 minor effect, while10  M of divalent Ni and Zn ions shows at 14 This finding can give some explanation for the antimicrobial activity of 15 monovalent copper ions (Cu(I))as well as Although mechanism that under the 17 an unfavorable carbon molecular oxygen 18 concentration and elevated temperatures, the antibacterial action Cu(I) ions is 19 boosted, with a 10 6 bacterial population eliminated in less than 1 by 0.4mM of 20 Cu(I). Microscopy checking of E.coli morphology and scattering testes showed 21 mortality of bacteria with almost no lysis. These results suggest rapid and lethal 22 metabolic damage is the main