Miracle-dz/UniFAR-FTUs huggingface dataset:
INTERNATIONAL CONFERENCE ON HARMONIZATION RECOMMENDED FORCED DEGRADATION STUDIES AND DEVELOPMENT OF A NEW VALIDATED ISOCRATIC REVERSE-PHASE ULTRA HIGH-PERFORMANCE LIQUID CHROMATOGRAPHY METHOD FOR THE SIMULTANEOUS ESTIMATION OF TELMISARTAN AND AMLODIPINE I

Objective: The objective of this research work is to develop a simple, rapid, cost-effective, accurate, precise, and robust stability-indicating reversephase ultra-high performance liquid chromatography method for the quantitative estimation of telmisartan (TEL) and amlodipine (AMD) in combined tablet dosage form. Methods: The method uses Poroshell 120EC-C18 column (4.6 mm × 50 mm, 2.7 μm) with an optimized mobile phase containing acetonitrile:50 mM ammonium acetate buffer in the ratio (45:55 v/v), pH adjusted to 4.5 with acetic acid. The flow rate was 0.5 ml/min, column temperature at 25°C and detection was monitored by a PDA detector at a wavelength of 245 nm. International Conference on Harmonization (ICH) recommended stress degradation studies were performed on TEL, AMD standard drugs, and tablet formulations; further stressed samples were analyzed by the proposed method. Results: Major degradation of TEL and AMD was observed under acidic, alkali, hydrolytic and oxidation conditions. The described method was validated as per the ICH guideline and validation parameters such as system suitability, linearity, accuracy, precision, specificity, and robustness results were within acceptable limits. Conclusion: The method was found to be suitable and accurate for quantitative estimation and stability study of title drugs in pharmaceutical preparations.
Seismic Facies Analysis by clustering of the SOM Among the statistical and neural networks unsupervised seismic pattern recognition

A new alternative to build seismic facies maps is presented. We propose to use matching pursuit with timefrequency dictionaries in each geological oriented segment of the temporal seismic trace associated with the Self Organizing Maps (SOM) as a clustering tool. Jointly, they could be used as a seismic facies estimator. The technique was applied to a real data from a deep-water field in the Campos Basin, Brazil.
The application of text mining algorithms in summarizing trends in anti-epileptic drug research

Content summarization is an important area of research in traditional data mining. The volume of studies published on anti-epileptic drugs (AED) has increased exponentially over the last two decades, making it an important area for the application of text mining based summarization algorithms. In the current study, we use text analytics algorithms to mine and summarize 10,000 PubMed abstracts related to anti-epileptic drugs published within the last 10 years. A Text Frequency – Inverse Document Frequency based filtering was applied to identify drugs with highest frequency of mentions within these abstracts. The US Food and Drug database was scrapped and linked to the results to quantify the most frequently mentioned modes of action and elucidate the pharmaceutical entities marketing these drugs. A sentiment analysis model was created to score the abstracts for sentiment positivity or negativity. Finally, a modified Latent Dirichlet Allocation topic model was generated to extract key topics associated with the most frequently mentioned AEDs. Results of this study provide accurate and data intensive insights on the progress of anti-epileptic drug research.
Dielectric characteristic of dichlorodifluoromethane (R12) gas and mixture with /air as an alternative to gas

In this study, dichlorodifluoromethane (R12) gas and mixtures with nitrogen (N2) and air at different pressures and mixing ratios have been investigated and showed good alternative to SF6 gas in terms of high-voltage application. Mixed gases contain R12 gas, they offer good dielectric properties and possibility to be used in low-temperature environment. Synergistic effects and self-recoverability test have been performed. Dielectric strength under quasi-uniform field showed in the order of SF6 > R12 > N2 > air in alternating current (AC), direct current (DC) and impulse was examined. Mixture R12/N2 (80/20%) could reach over 0.90–0.95 times to that of SF6 gas at 50 lb/in2 at AC and R12/air (70/30%) gives 0.80–0.90 to SF6 gas. R12 gas presents brilliant self-recoverability. The optimal ratio to switch SF6 gas is R12/N2 (80/20%) and R12/air (70/30%) is based on the authors’ experimental condition and setup.
THREE DIMENSIONAL NUMERICAL INVESTIGATIONS OF WIND ENVIRONMENT AROUND LANQIYING BUILDINGS

The three-dimensional wind environment in Lanqiying community of Beijing city, which is complicated due to the dense distribution of the highrise buildings, is investigated by computational fluid dynamics method. The turbulent flow past the buildings is simulated by solving the incompressible Reynolds-averaged Navier-Stokes equations. Both the reverse flow between the buildings and the recirculation of the wake can be observed. The spectrum analysis of aerodynamics coefficient are successfully obtained and compared with the twodimensional results. The vortex interactions with each other result in different characteristic frequencies and power values, corresponding to various-scale vortex shedding behind the buildings.
Reproductive biology of the angular angel shark Squatina guggenheim (Chondrichthyes: Squatinidae) off Patagonia (Argentina, southwestern Atlantic)

The reproductive biology of the angel shark Squatina guggenheim was described based on 584 animals sampled in the San Matias Gulf, Argentina, between January and December 1996. Both sexes of S. guggenheim reached similar total length and matured at similar sizes (between 73 and 76 cm total length). In males, testes were paired and showed diametric development. Adult males were predominant in the austral autumn and winter, and were capable of mating all year round. In females, only the left ovary was functional. The maximum follicular diameter recorded (6 cm) was observed during the austral autumn and winter, with ovulation occurring during spring and summer. The size distribution of the follicles indicated that adult females presented different maturational stages in all the seasons. No post-ovulatory follicles were distinguished in any of the females examined. The seasonal analysis showed significant differences in sex abundance. Adult males were predominant in autumn and winter, juvenile males in spring, and adult females in summer. Only a few pregnant animals were caught in January, May and September. The results suggest that S. guggenheim females show a biannual reproductive cycle with gestation taking at least one year, and that the San Matias Gulf is not one of their main breeding areas.
Unbiased Monte Carlo valuation of lookback, swing and barrier options under variance gamma models

We introduce fast and unbiased methods for Monte Carlo valuation of lookback, swing, and barrier options under variance gamma models. For the valuation of lookback and swing options, a procedure to draw samples of final value, infimum, and supremum of variance gamma processes with additional drift term up to arbitrary precision is developed, for barrier options, a separate method is designed to improve the performance by exploiting the particular payoff structure. Both algorithms substantially rely on adaptive difference-of-gammas brige sampling, a newly introduced enhancement of the truncated difference-of-gammas bridge sampling method, which was originally presented in Avramidis et al. (2003) and successfully applied to lookback and barrier option valuation in Avramidis and L’Ecuyer (2006). By applying our algorithms to examples treated in Avramidis and L’Ecuyer (2006) we observe considerable reductions in computational effort and memory requirements. Furthermore, our algorithms feature a priori precision bounds, whereas Avramidis and L’Ecuyer (2006) are restricted to a posteriori bounds.
Strong coupling constant extraction from high-multiplicity Z + jets observables.

We present a strong coupling constant extraction at next-to-leading order QCD accuracy using ATLAS Z + 2 ,3,4 jets data. This is the first extraction using processes with a dependency on high powers of the coupling constant. We obtain values of the strong coupling constant at the Z mass compatible with the world average and with uncertainties commensurate with other next-to-leading order extractions at hadron colliders. Our most conservative result for the strong coupling constant is α S ( M Z ) = 0.117 8 + 0.0051 − 0.0043 .
SUGARCANE TRASH MANAGEMENT ASSESSED BY THE INTERACTION OF YIELD WITH SOIL... 1709

Currently, sugarcane plays an important global role, particularly with a view to alternative energy sources. Thus, in a sugarcane field of the mill Vale do Paraná S/A Álcool e Açúcar, Rubineia, São Paulo State, managed under two green cane harvest systems (cane trash left on and cane trash removed from the soil), Pearson and spatial correlations between the sugarcane yield (variety RB855035 in the third cut) and soil physical and chemical properties were studied to identify the property best correlated with stalk yield and the best harvest method. For this purpose, two geostatistical grids (121 sampling points on 1.30 ha) were installed on a eutrophic Red Argisol (homogeneous slope of 0.065 m m-1), in 2011, to determine the properties: stalk yield and sugarcane plant population, and soil resistance to penetration, gravimetric moisture, bulk density, and carbon stock, in the layers 0-0.20 and 0.20-0.40 m. The data were analyzed by descriptive, linear correlation and geostatistical analysis. In both treatments, the property stand density was best correlated with sugarcane yield (r = 0.725 in the trash mulching treatment TM and r = 0.769 in the trash removal treatment TR). However, in relation to the soil properties, bulk density (0-0.20 m) was best correlated (r = 0.305 in TM, r = 0.211 in TR). Similarly, from the spatial point of view, stand density was the property that best explained the sugarcane yield. However, in the TM treatment the density (0.20-0.40 m) was
In vitro differentiation and plant regeneration from root and other explants of juvenile origin in pea (Pisum sativum L.)

In vitro regeneration of pea explants (Pisum sativum L. var. ‘Lincon’) was done in 49 different combinations and concentrations of BAP, BAP and NAA, BAP and IBA, TDZ, TDZ and Adenine for shoot regeneration from hypocotyl, root, leaf and cotyledonary node. High frequency shoot regeneration was obtained in hypocotyl (81.43%), root(83.53%) and cotyledonary node(72.76%) on MS medium supplemented with 4.50 mg/l BAP and 1.86mg/l NAA, 2.00mg/l TDZ and4.50 mg/l BAP and 1.86mg/l NAA respectively. No shoot regeneration was obtained from leaf explants on any of the combination used. Shoot elongation was observed on the same medium used for shoot regeneration respectively.MS medium supplemented with 0.20 mg/l IBA was found best for root regeneration from in vitro raised shoots. The plantlets were able to regenerate within 6-7 weeks. The regenerated plantlets were acclimatized in pre-sterilized cocopeat.
MARCADOR SCAR NA DISSEMINAÇÃO DE CULTIVARES DE VINCA

Sequence-Characterized Amplified Region (SCAR) appears as a useful technique for genetic purity testing and variety discrimination, applicable to species in which some other techniques have failed. In particular, this technique is very attractive with species in which RAPD results were not consistent. The RAPD polymorphic bands were cloned, sequenced and from the sequence information, primers pairs for normal PCR were developed. Since the probability of obtaining successful SCAR primers from RAPD polymorphic bands was about 50%, a larger number of RAPD polymorphic bands are needed to develop sufficient SCAR primers for varietal discrimination in vinca. In addition, the efficiency of the SCAR technique is strongly affected by the quality of DNA extracted from seeds. The SCAR banding patterns obtained from vinca seed were consistent and repeatable making the results reliable for genetic purity testing and variety discrimination. The SCAR technique is simple, fast, relatively inexpensive and allows the use of DNA extracted from dry seeds, which is very important in a seed-quality evaluating program
HOW INNOVATIVE ARE UK FIRMS ? EVIDENCE FROM THE CIS 4 ON SYNERGIES BETWEEN TECHNOLOGICAL AND ORGANISATIONAL INNOVATIONS

Using data from the 4 th UK Community Innovation Survey (CIS4) this paper explores the diffusion of a range of innovative activities (encompassing process, product, machinery, marketing, organization, management and strategic innovations) across 16383 British companies in 2004. Building upon a simple theoretical model it is shown that the use of each innovation is correlated with the use of all other innovations. It is shown that the range of innovations can be summarised by two multi innovation factors, labelled here „organisational‟ and „technological‟, that are complements but not substitutes for each other. Three clusters of firms are identified where intensity of use of the two sets of innovation is: below average (56.9% of the sample); intermediate but above average (23.7%); and highly above average (19.4%). Distinctive characteristics are found to be common to the companies in each cluster. Finally, it is shown that innovativeness tends to persist over time.
Ultra low-cycle fatigue modeling of welded joints under multi-axial strain conditions for better seismic design

When ductile steel systems fail during earthquakes, they tend to fail near connection regions and often under ultra low-cycle fatigue (ULCF) conditions. To determine connection fatigue capacities for design, static-cyclic laboratory tests on connection assemblies or components are often used; however, the complicated multi-axial stress states that exist under real earthquake loading are rarely applied during such tests. With maximum distortion strain energy theory suggesting that multiaxial strain states may reduce the effective yield of materials, there exists the possibility for increased connection fatigue damage under multi-axial strain conditions.
Wald entropy formula and loop quantum gravity

We outline how the Wald entropy formula naturally arises in loop quantum gravity based on recently introduced dimension-independent connection variables. The key observation is that in a loop quantization of a generalized gravity theory, the analog of the area operator turns out to measure, morally speaking, the Wald entropy rather than the area. We discuss the explicit example of (higher-dimensional) Lanczos-Lovelock gravity and comment on recent work on finding the correct numerical prefactor of the entropy by comparing it to a semiclassical effective action.
PHYTOCHEMICAL SCREENING AND GAS CHROMATOGRAPHY-MASS SPECTROSCOPY ANALYSIS OF BIOACTIVE COMPOUNDS AND BIOSYNTHESIS OF SILVER NANOPARTICLES USING SPROUT EXTRACTS OF VIGNA RADIATA L. AND THEIR ANTIOXIDANT AND ANTIBACTERIAL ACTIVITY

Objectives: The present study was aimed to investigate the facile synthesis of silver nanoparticles (AgNPs) using the green gram sprout extract (GGSE) of Vigna radiata L. and also in vitro studies of antioxidant and antimicrobial activities. Methods: Gas chromatography-mass spectroscopy techniques have been used for the qualitative and quantitative evaluation of the phytochemicals present in the green gram seedlings. The antioxidant activity of AgNPs and GGSE was analyzed using the 1,1-diphenyl-2-picrylhydrazyl (DPPH) assay. In vitro antibacterial activity was performed using the agar well diffusion method. Results: The presence of various secondary metabolites such as flavonoids, steroids, terpenoids, alkaloids, amino acids, polyphenol, glycoside, and protein was found in samples. The major chemical compounds of V. radiata were n-hexadecanoic acid, stigmasterol, caffeine, hexadecanoic acid, cholest-5-en-3-ol (3.beta.)-, and cyclopentane. The percentage of DPPH activity was enhanced on increasing the concentration of AgNPs. In vitro antibacterial effect of the diverse concentrations of AgNPs was investigated against each Gram-negative (Klebsiella aerogenes, and Escherichia coli) and Gram-positive (Bacillus substilis and Staphylococcus aureus) bacterial strains. Conclusion: The result suggests that biosynthesized AgNPs have good antibacterial and antioxidant activity and might be a potential for the bioactive components.
The Race of a Criminal Record: How Incarceration Colors Racial Perceptions

In the United States, racial disparities in incarceration and their consequences are widely discussed and debated. Previous research suggests that perceptions of crime and the operations of the criminal justice system play an important role in shaping how Americans think about race. This study extends the conversation by exploring whether being incarcerated affects how individuals perceive their own race as well as how they are perceived by others, using unique longitudinal data from the 1979 National Longitudinal Survey of Youth. Results show that respondents who have been incarcerated are more likely to identify and be seen as black, and less likely to identify and be seen as white, regardless of how they were perceived or identifed previously. This suggests that race is not a fxed characteristic of individuals but is fexible and continually negotiated in everyday interactions.
Assessment of spatial and temporal dynamics of livelihoods: A methodological perspective

Increased international attention to rural poverty alleviation and sustainable development underscores the need for better tools for analyzing the factors and conditions that shape livelihoods and for assessing the livelihood impacts of projectand policy-interventions. The first aspect encompasses important spatial dynamics, while the second addresses both temporal and spatial dynamics. To be effective, such approaches must accommodate the complex and multidimensional nature of livelihood systems by: i) using appropriate indicators of livelihoods outcomes and embracing multiple components of a livelihood system; ii) analyzing the influence of multiple and complex factors, including development interventions; iii) addressing differential impacts by taking appropriate aggregation at the village level. Powerful new geomatics technologies offer new ways to deal with spatial variability, and can be combined with innovative social-science approaches for more efficient socio-economic data collection and analysis. This * A paper submitted and presented to the 9th Biennial Conference on "Ecological Sustainability and Human Well-Being" 15-18 December 2006 at India Habitat Centre, New Delhi. paper discusses key principles for designing appropriate methods and reports lessons learned from our own experience in Jharkhand state, India and Kutai Barat district in East Kalimantan, Indonesia. In these two study areas, with relatively low levels of development and high forest cover, we assessed livelihood systems by: i) using available, broad range data of assets and socioeconomic data in indices of development from secondary source; ii) using geomatics tools for sampling and analyses that encompass a range of theoretically important variables (e.g. road access; market access; proximity to large projects; tribal affiliation; topography; land suitability); iii) identifying key factors that characterize within-village stratification and designing household sampling accordingly; iv) aggregating unit of analysis to address differential impacts and relationships among livelihood components. Multilevel regression analysis is used to address hierarchical or differential structure in the data. The paper provides guidance for improved landscape-scale livelihoods analysis and targeting and identifies a way forward for further method improvement.
A JOINT CLASSIFICATION METHOD FOR TLS POINT CLOUD BY INTENSITY AND COLOR INFORMATION

Current TLS can collect intensity returns which reflect the physical characteristics of targets. Numerous studies have utilized the intensity values to classify point cloud data. However, the intensity values acquired are influenced by numbers of factors and needed to be calibrated. The classification accuracy of methods using intensity values largely depends on the accuracy of the calibration model. Experiments showed that the accuracy of the calibrated intensity data is only ideal within certain range (between the scanner and the target) limits. Most TLS can also obtain color information which can be used as a complementary to intensity in point cloud classification. In this paper, a new classification method is proposed. This method mainly utilizes the calibrated intensity data and the color information is employed as a constraint. Compared with the previous methods, the proposed method is fault-tolerant with the calibrated intensity data, thus improving the classification results. In this study, the data of intensity and color information of the Faro Focus3D 120 terrestrial laser scanner are investigated. The experiment results indicated that the proposed method can improve the accuracy of the point cloud data classification and can also improve the credibility and reliability of classification results when the intensity data is poorly calibrated.
Rates of decline and recovery of coral cover on reefs impacted by, recovering from and unaffected by crown-of-thorns starfish Acanthaster planci: a regional perspective of the Great Barrier Reef

Manta tow surveys of the perimeters of reefs throughout the Great Barrier Reef (GBR) assessed broad-scale changes in hard coral cover on reefs impacted by, recovering from and unaffected by Acanthaster planci outbreaks. Mean coral cover was 16 to 40 % on reefs with no history of A. planci outbreaks, depending on location on the GBR. Coral cover increased at approximately 2% yr -1 on southern reefs, while there was no significant increase on such reefs in other regions. Hard coral cover on reefs with A. planci outbreaks declined at a mean annual rate of 6 % to an average level of 9%. Coral cover on southern reefs that were recovering from sustained A. planci outbreaks increased at about 4% yr -1 while such reefs showed an annual increase of 0.8% in the remaining regions. A total of 78% of recovering reefs showed a positive growth rate, assuming linear growth, the time for coral cover to increase by 30%, was estimated at between 5 yr and well over 1000 yr. In addition to providing regional estimates of the decline and recovery of reefs due to A. planci outbreaks, this study highlights the variability in rate of recovery between reefs and raises the possibility that not all reefs will recover from sustained outbreaks.
Calculation of Quasi-one-dimensional Interacting Electron Gas Using the Hartree-Fock Method

In this paper, the Hartree-Fock method has been formulated to investigate some of the ground state properties of quasi-one-dimensional interacting electron gas in the presence of the magnetic field. The bare coulomb interaction between electrons has been assumed. For this system, we have also computed some of its thermodynamic and magnetic properties such as the energy, pressure, incompressibility, spin-polarization and magnetic susceptibility for different values of the magnetic field. Based on the results, the total energy increases by increasing the density for all relevant magnetic fields. The system becomes more stable by increasing the magnetic field. The system also shows a phase transition at high magnetic fields.