Miracle-dz/UniFAR-FTUs huggingface dataset:
Visualizing Research: A Guide to the Research Process in Art and Design: Carole Gray & Julian Malins

Those of us charged with imparting and integrating research methods suitable for practising artists and designers in the UK art schools these days can hardly complain about any dearth of advice or lack of resources in the field. Once the acronym army of the UKGCE (United Kingdom Council for Graduate Education, 2001), AHRB, now C (Arts and Humanities Research Board, now Council, 2003) and QAA (Quality Assurance Agency, 2004) had between them produced a skein of expectations about what researchers in these areas might need, there could be discerned a skeleton structure of guidelines upon which a plethora of pedagogical body-building programmes has been visited, all sharing the laudable aim of toning the musculature of research in art and design.
Sensorless vector control of interior permanent magnet synchronous motor drives at very low speed without signal injection

In recent years, sensorless control of interior permanent magnet synchronous motors (IPMSMs) has been a research area of significant interest. A multitude of solutions have been proposed for sensorless operation but most of them fail to deliver satisfactory performance in the low speed region. This study describes the active flux concept, which is used to design a rotor position and speed observer. The proposed observer does not require any speed adaptation. Hence, speed estimation errors especially in the low speed region do not affect the performance of the observer. An online stator resistance estimator is proposed to further enhance the low speed operation of the observer. The proposed observer is capable of delivering accurate state estimation at very low speeds including standstill without signal injection. Simulation and experimental results at 0 and 5 rpm confirm the effectiveness of the proposed sensorless approach.
Endothelial Progenitor Cells: An Appraisal of Relevant Data from Bench to Bedside

The mobilization of endothelial progenitor cells (EPCs) into circulation from bone marrow is well known to be present in several clinical settings, including acute coronary syndrome, heart failure, diabetes and peripheral vascular disease. The aim of this review was to explore the current literature focusing on the great opportunity that EPCs can have in terms of regenerative medicine.
Laser interferometer using a dual interference method

A stabilised Michelson interferometer system using a new interference mode has been developed, in which a specially designed beam-splitter produces two complementary interference patterns. With differential detection, the laser intensity noise is efficiently eliminated, and the system is simpler and stabler. The measured displacement sensitivity is 10−2 Ȧ/ √(HZ).
Coupled‐fed shorted strip antenna with an inductively coupled branch strip for low‐profile, small‐size LTE/WWAN tablet computer antenna

A low‐profile, small‐size (10 × 40 mm2 on a thin dielectric substrate) planar LTE/WWAN antenna suitable for slim tablet computer application is presented. The antenna is formed by a coupled‐fed shorted strip antenna and an inductively coupled branch strip, with a chip inductor of 22 nH connected therebetween. At higher frequencies, owing to the high inductive reactance provided by the chip inductor, the branch strip will have very small effects on the antenna performances, and the coupled‐fed shorted strip antenna alone can provide a high‐band operation of 1710–2690 MHz. At lower frequencies, the embedded chip inductor can decrease the antenna's required resonant length, and the coupling feed can greatly widen the bandwidth of the excited resonant mode such that the antenna can cover a low‐band operation of 704–960 MHz. Good radiation characteristics of the antenna in the low‐band and high‐band operations are also obtained. Details of the proposed antenna and its experimental and simulated results are presented. © 2014 Wiley Periodicals, Inc. Microwave Opt Technol Lett 56:1041–1046, 2014
In-silico Modeling of the Micromechanics of Fibrous Scaffolds and Stiffness Sensing by Cells

Mechanical properties of the tissue engineering scaffolds are known to play a crucial role in tissue regeneration. Here, we have utilized discrete network and finite element models to study fibrous scaffold mechanics and its dependence on structure. We have considered two loading conditions, first, uniaxial elongation (macroscopic), and second, localized cellular forces (microscopic). Using these two scenarios, we have tried to establish a link between scaffold micromechanics and its macroscopic mechanical properties. We have demonstrated that the macroscopic elastic modulus of fibrous scaffold is dependent on the sample shape, size and the degree of fiber fusion. Under microscopic loading conditions the deformation of the fibrous scaffolds is anisotropic with an orientation dependent decay with distance. Further, we explored the stiffness sensing under the conditions of fixed stress or fixed strain application by the cells. With fixed strain, we found that the stiffness sensed by a cell is proportional to scaffold's macroscopic Young's modulus. However, for fixed stress application, it also depends on cell's elasticity with stiffness experienced by stiff and soft cells differing by an order of magnitude. The analyses demonstrate that there exists a gap between mechanical properties of the fibrous scaffolds as measured from the macroscopic testings and those sensed by the cells. This warrants a need for extreme care during the designing and reporting of experiments involving cell-scaffold interactions. The insights from this work will help in the designing of tissue engineering scaffolds for applications where mechanical stimuli are a critical factor
Optimization of the Mashaer Shuttle-Bus Service in Hajj: Arafat-Muzdalifah Case Study

Hajj, the fifth pillar of Islam, is held annually in the month of Dhul Al-Hijjah, the twelfth month, in the Islamic calendar. Pilgrims travel to Makkah and its neighbouring areas—Mina, Muzdalifah, and Arafat. Annually, about 2.5 million pilgrims perform spatiotemporally restricted rituals in these holy places that they must execute to fulfil the pilgrimage. These restrictions make the task of transportation in Hajj a big challenge. The shuttle bus service is an essential form of transport during Hajj due to its easy availability at all stages and ability to transport large numbers. The current shuttle service suffers from operational problems; this can be deduced from the service delays and customer dissatisfaction with the service. This study provides a system to help in planning the operation of the service for one of the Hajj Establishments to improve performance by determining the optimal number of buses and cycles required for each office in the Establishment. We will also present a case study in which the proposed model was applied to the non-Arab Africa Establishment shuttle service. At the same time, we will include the mechanism for extracting the information required in the tested model from the considerably large GPS data of 20,000+ buses in Hajj 2018.
A Novel Vitronectin Peptide Facilitates Differentiation of Oligodendrocytes from Human Pluripotent Stem Cells (Synthetic ECM for Oligodendrocyte Differentiation)

Simple Summary Oligodendrocyte (OD) is a cell type of great interest in the regenerative medicine for several neurological diseases. This study provides a new defined coating material for the differentiation of ODs from human pluripotent stem cells. A new peptide named VNP2, designed by in silico simulation, can be readily produced in a large amount and stably immobilized on the bottom of culture vessel. Upon using for differentiation of ODs, VNP2 promoted the differentiation efficiency more than the conventional coating materials did. Furthermore, transcriptomic analysis revealed molecular clues for the differentiation promoting activity of VNP2. Therefore, this peptide may be used as a favored coating material for the culture and differentiation of ODs. Abstract Differentiation of oligodendrocytes (ODs) presents a challenge in regenerative medicine due to their role in various neurological diseases associated with dysmyelination and demyelination. Here, we designed a peptide derived from vitronectin (VN) using in silico docking simulation and examined its use as a synthetic substrate to support the differentiation of ODs derived from human pluripotent stem cells. The designed peptide, named VNP2, promoted OD differentiation induced by the overexpression of SOX10 in OD precursor cells compared with Matrigel and full-length VN. ODs differentiated on VNP2 exhibited greater contact with axon-mimicking nanofibers than those differentiated on Matrigel. Transcriptomic analysis revealed that the genes associated with morphogenesis, cytoskeleton remodeling, and OD differentiation were upregulated in cells grown on VNP2 compared with cells grown on Matrigel. This new synthetic VN-derived peptide can be used to develop a culture environment for efficient OD differentiation.
Zur Methodik der Videokapillarmikroskopie: Bestimmung geometrischer und dynamischer Meßparameter - Video Capillary Microscopy: Determination of Geometrical and Dynamic Parameters

Schlüsselwörter: Nagelfalzkapillarmikroskop, anscheinend gesunde Probanden, Standardisierung Es wird ein System zur Erfassung von Geometrie und Perfusion von Nagelfalzkapillaren vorgestellt. Die Durchführung der Kapillaroskopie sowie die Erfassung geometrischer und dynamischer Meßgrößen wird diskutiert. Insbesondere die Problematik der Bestimmung von Kapillarbzw. Erythrozytensäulendurchmesser wird untersucht. Dabei werden Ergebnisse der bisher üblichen »Monitorauswertung« mit Ergebnissen einer bildrechnerunterstützten Auswertung verglichen. Im Mittel werden bei der Monitorauswertung die Erythrozytensäulendurchmesser um ca. 36% unterschätzt. Die Methodik wird demonstriert an einer Untersuchung von n = 100 anscheinend gesunden Probanden im Alter zwischen 20 und 40 Jahren. Die gefundenen geometrischen und dynamischen Meßgrößen unterscheiden sich für Männer und Frauen nicht.
LINE WEIGHTS OF CONSTANT MASS (AND SINK RATES) FOR SPANISH-SYSTEM PATAGONIAN TOOTHFISH LONGLINE VESSELS

CCAMLR Conservation Measure 25-02 requires Spanish-system longline vessels to attach 8.5 kg weights at 40 m intervals on longlines to minimise interactions with seabirds. The weights typically used are collections of rocks enclosed in netting bags. During fishing operations the netting bags abrade on the seabed causing rocks to be lost and the weights to become progressively lighter, requiring ongoing repair. This problem can be solved by use of hydrodynamically shaped (e.g. torpedo-shaped) steel weights, which are smaller for equivalent weight, and require no maintenance. An experiment was conducted on a Spanish-system longline vessel to determine the relationship between the sink rates of longlines equipped with bags of rocks (4, 6 and 8 kg) and those with steel weights of equivalent masses. The purpose of the experiment was to provide vessel operators with the option of substituting steel weights for rock weights while remaining in compliance with the sink rates associated with the line-weighting provisions of Conservation Measure 25-02. Both the Spanish system and the newly developed Chilean longline (a modified version of the former method to avoid fish loss by toothed whales) were tested in the experiment. Spanish-system longlines with 8 kg rock weights every 40 m averaged 0.22 m s –1 to 2 m depth, which would be equal to, or exceeded by, lines with 5 kg steel weights. Sink rates of Chilean longlines greatly exceeded those of the Spanish system, ranging from 0.68 m s –1 (4 kg rocks) to 1.31 m s –1 (8 kg steel) in the shallow depth ranges. Hydrodynamically shaped steel weights weighing 5 kg would be an appropriate substitute for 8.5 kg rock weights irrespective of fishing method.
Using a Machine Learning Algorithm to Predict the Likelihood of Presence of Dental Caries among Children Aged 2 to 7

Background: Dental caries is the most common chronic childhood infectious disease and is a serious public health problem affecting both developing and industrialized countries, yet it is preventable in most cases. This study evaluated the potential of screening for dental caries among children using a machine learning algorithm applied to parent perceptions of their child’s oral health assessed by survey. Methods: The sample consisted of 182 parents/caregivers and their children 2–7 years of age living in Los Angeles County. Random forest (a machine learning algorithm) was used to identify survey items that were predictors of active caries and caries experience. We applied a three-fold cross-validation method. A threshold was determined by maximizing the sum of sensitivity and specificity conditional on the sensitivity of at least 70%. The importance of survey items to classifying active caries and caries experience was measured using mean decreased Gini (MDG) and mean decreased accuracy (MDA) coefficients. Results: Survey items that were strong predictors of active caries included parent’s age (MDG = 0.84; MDA = 1.97), unmet needs (MDG = 0.71; MDA = 2.06) and the child being African American (MDG = 0.38; MDA = 1.92). Survey items that were strong predictors of caries experience included parent’s age (MDG = 2.97; MDA = 4.74), child had an oral health problem in the past 12 months (MDG = 2.20; MDA = 4.04) and child had a tooth that hurt (MDG = 1.65; MDA = 3.84). Conclusion: Our findings demonstrate the potential of screening for active caries and caries experience among children using surveys answered by their parents.
Determinants of the Underlying Causes of Mortality during the First Wave of COVID-19 Pandemic in Saudi Arabia: A Descriptive National Study

Since the emergence of the COVID-19 pandemic, the mortality statistics are constantly changing globally. Mortality statistics analysis has vital implications to implement evidence-based policy recommendations. This study aims to study the demographic characteristics, patterns, determinants, and the main causes of death during the first half of 2020, in the Kingdom of Saudi Arabia (KSA). Methodology: A retrospective descriptive study targeted all death (29,291) registered in 286 private and governmental health settings, from all over KSA. The data was extracted from the ministry of health’s death records after the ethical approval. The International Classification of Diseases (ICD-10) and WHO grouping, were used to classify the underlying causes of deaths. The collected data were analyzed using the appropriate tables and graphs. Results: 7055 (24.9%) died at the middle age (40–59 year), and 19,212 (65.6%) were males, and 18,110 (61.8%) were Saudi. The leading causes of deaths were non-communicable diseases (NCDs) 15,340 (62.1%), mainly Cardiovascular diseases (CVDs) 10,103 (34.5%). There was a significant relationship between the main causes of deaths and sex (p < 0.05) and nationality (p = 0.01). Conclusion: NCDs mainly CVDs are the leading cause of death. The COVID-19 mortalities were mainly in males, and old age > 55 year. The lockdown was associated with a reduction in the NCDs and Road traffic accidents mortalities.
A New Mobility Extraction Technique Based on Simultaneous Ultrafast $I_{d}$ – $V_{g}$ and $C_{\rm cg}$ – $V_{g}$ Measurements in MOSFETs

Channel carrier mobility in MOSFETs is a key parameter for process development, material selection, and device modeling. The existing techniques for mobility evaluation suffer from one or more of the following shortcomings: slow speed and vulnerability to fast trapping, drain bias dependence, cable-changing, sensitivity to gate leakage, complex procedure, and a need for simulation. This paper proposes and develops a new technique to overcome these shortcomings. - and - are simultaneously measured so that the effect of on mobility is inherently taken into account, and the measured mobility becomes -independent. The cable connection switching between - and - measurements is avoided, and the measurement completes in one pulse. This allows the measurement time reducing to the order of microseconds and, in turn, minimizing the effect of charge trapping. Unlike the standard high-frequency - , is independent of gate leakage here, and the applicability of new technique to thin gate oxides of high gate leakage will be demonstrated. These advantages, together with its easy implementation, should make this technique a simple and robust tool for process development, material selection, and device modeling in future generations of CMOS technology.
Identification and Construction of a Predictive Immune-Related lncRNA Signature Model for Melanoma

Objective The occurrence and development mechanisms of melanoma are related to immunity and lncRNAs. Therefore, it is necessary to systematically explore immune-related lncRNA profiles to help improve the prognosis of melanoma. Methods We integrated immune-related lncRNAs and the basic clinical information of melanoma patients in the TCGA dataset. Immune-associated lncRNAs were selected by differential expression screening and enriched for analysis. After univariate and multivariate Cox regression analyses, a new prognostic indicator based on immune-associated lncRNAs was established. Results Overall, differentially expressed immune-related lncRNAs were significantly associated with clinical outcomes in patients with melanoma. A prognostic model was then established based on 14 immune-associated lncRNAs (LRRC8C-DT, AC021188.1, MALINC1, CCR5AS, EIF2AK3-DT, AC022306.2, AC242842.1, AL034376.1, AL662844.4, AC009065.3, AC099811.3, AC125807.2, SPINT1-AS1 and AC009495.2). Melanoma patients in the high-risk group had worse overall survival than those in the low-risk group. The AUC of the risk score was 0.786. Conclusion This study identified several clinically significant immune-related lncRNAs and established a relevant prognostic model, which provided a molecular analysis of immunity in melanoma and potential prognostic lncRNAs for melanoma.
Analytically determined quasi-static parameters of shielded or open multiconductor microstrip lines

An exact analytical expression for the capacitance matrix of a shielded or open multiconductor microstrip structure is derived by solving the system's dual integral equations by constructing a Volterra boundary-value problem (BVP). The solution is expressed in terms of infinite matrices with very good convergence properties. This new approach uses a series of Bessel functions rather than trigonometric series to approximate the solution which results in an efficient algorithm. Simplified formulas are given for the even and odd capacitance of symmetric coupled microstrip lines and compared to the results given by the finite analytical solution available in this particular case. Numerical examples demonstrate that the method yields accurate results and is computationally effective for structures having a large number of conductors.
VALIDATION OF EMISSION FACTORS FOR ROAD VEHICLES BASED ON STREET TUNNEL MEASUREMENTS

The emission behaviour of road vehicles is regularly estimated by the use of emission factors and models. But there is only limited information available about the validity of such factors or models in real world situations. This is because validation requires roadside measurements and these add an additional element of uncertainty in the form of pollutant dispersion behaviour. Tunnel measurements can help to overcome this problem. Road tunnels can be used as big laboratories because the boundary conditions within such tunnels are well known. Such measurements were undertaken in a 10 km long road tunnel in Austria for a period of six weeks during autumn 1998 and another four weeks during spring 1999. An analysis of the data showed that CO emissions derived from the measurements were in good agreement with the emission factors; surprisingly, this was not the case for NOx, especially for NOx emissions from heavy duty vehicles. Due to the fact that the HDV share of the traffic was up to 35% of total traffic volume the effects of unbalanced emission factors were considerable. Differences of up to a factor of 1.6 between measured and calculated emission factors were recorded.
MT1-MMP Cooperates with TGF-β Receptor-Mediated Signaling to Trigger SNAIL and Induce Epithelial-to-Mesenchymal-like Transition in U87 Glioblastoma Cells

Epithelial-to-mesenchymal transition (EMT) recapitulates metastasis and can be induced in vitro through transforming growth factor (TGF)-β signaling. A role for MMP activity in glioblastoma multiforme has been ascribed to EMT, but the molecular crosstalk between TGF-β signaling and membrane type 1 MMP (MT1-MMP) remains poorly understood. Here, the expression of common EMT biomarkers, induced through TGF-β and the MT1-MMP inducer concanavalin A (ConA), was explored using RNA-seq analysis and differential gene arrays in human U87 glioblastoma cells. TGF-β triggered SNAIL and fibronectin expressions in 2D-adherent and 3D-spheroid U87 glioblastoma cell models. Those inductions were antagonized by the TGF-β receptor kinase inhibitor galunisertib, the JAK/STAT inhibitors AG490 and tofacitinib, and by the diet-derived epigallocatechin gallate (EGCG). Transient gene silencing of MT1-MMP prevented the induction of SNAIL by ConA and abrogated TGF-β-induced cell chemotaxis. Moreover, ConA induced STAT3 and Src phosphorylation, suggesting these pathways to be involved in the MT1-MMP-mediated signaling axis that led to SNAIL induction. Our findings highlight a new signaling axis linking MT1-MMP to TGF-β-mediated EMT-like induction in glioblastoma cells, the process of which can be prevented by the diet-derived EGCG.
Political Skill for Developing Construction Safety Climate

AbstractPolitical skill, which consists of social astuteness, interpersonal influence, networking ability, and apparent sincerity dimensions, is considered as one of the most important skills in general management. However, its importance in construction management, particularly construction safety management, is still not as well known. The aim of this research is to understand the role of political skill in implementing safety management tasks and developing construction safety climate. Quantitative research methodology was adopted to test the theoretical model developed in this research. Data were collected via a web-based online survey and the analysis was done using structural equation modeling (SEM) method. The results of the analysis support the research hypotheses which proposed that project personnel’s political skill positively influences the implementation of safety management tasks and promotes the development of construction safety climate. Apparent sincerity and social astuteness are the pol.