Miracle-dz/UniFAR-FTUs huggingface dataset:
Three-stage approach to aesthetic implant restoration: emergence profile concept.

Proper treatment planning and precise evaluation of various parameters (e.g., bone volume, soft tissues, dental anatomy, surgical and prosthetic components) are crucial for an aesthetic implant restoration. The three-stage approach of the emergence profile concept guides the selection of implant, healing abutment, and provisional prosthesis. Adaptation of the implant, provisional prosthesis, and crown restoration stages and their harmonious integration with the soft tissues enable the development of an optimal aesthetic result. This article demonstrates the incorporation of the emergence profile concept for aesthetic implant placement.
Stable user pairing in virtual MIMO systems: A game theoretical perspective

Virtual MIMO (VMIMO) technique has been envisioned to be an advanced technique for communication systems. In this paper, we consider a 2×2 VMIMO system, where two users are paired together to communicate with the base station simultaneously. User pairing is important for such a system since it determines the channel capacity of each pair of users, the system capacity, as well as the fairness among users. To consider the tradeoff between the system performance and user fairness, we study another concept of stability by formulating the user pairing problem as a symmetric paring game. Using a game theoretical analysis, we proof that the symmetric pairing problem exists a stable pairing solution, which is also Pareto efficient. Based on this result, we further develop a symmetric stable pairing (SSP) algorithm to find out a stable pairing for the VMIMO system. Simulation results show that the stable pairing given by SSP results in a high system capacity and an acceptable fairness.
Bis{2-[(Triphenylmethyl)amino]phenyl} diselenide acetonitrile monosolvate

The molecular structure of the title compound, C50H40N2Se2·C2H3N, shows a syn conformation of the benzene rings bound to the Se atoms, with an Se—Se bond length of 2.3529 (6) Å and a C—Se—Se—C torsion angle of 93.53 (14)°. The two Se-bonded aromatic ring planes make a dihedral angle of 18.42 (16)°. Intramolecular N—H⋯Se hydrogen bonds are noted. Intermolecular C—H⋯Se interactions give rise to supramolecular chains extended along [100]. One severely disordered acetonitrile solvent molecule per asymmetric unit was treated with SQUEEZE in PLATON [Spek (2009 ▶). Acta Cryst. D65, 148–155]; the crystal data take the presence of this molecule into account.
Software Ecosystem Orchestration: The Perspective of Complementors

Software ecosystems (SECOs) driven by platform business models have changed how consumer software is produced and marketed. Also in the enterprise software segment, value networks in the form of SECOs are replacing traditional business models and linear value chains. These SECOs involve three main types of actors: platform sponsor, complementors, and customers. Platform sponsor strategies have been researched broadly, but not the view of complementors. Further, there are few studies of real-world SECOs. In our research, we have investigated the complementor’s perspective on SECOs and their partnership with the platform sponsor. Through exploratory qualitative research using a practical case from the enterprise software industry, we have developed a partner management framework comprising the complementors’ value creation process, goals, enablers, and instruments. The model can be used generally to gain a better understanding of complementors, and by platform sponsors to improve their partner management processes.
Mex3c Mutation Reduces Adiposity and Increases Energy Expenditure

ABSTRACT The function of MEX3C, the mammalian homolog of Caenorhabditis elegans RNA-binding protein muscle excess 3 (MEX-3), was unknown until our recent report that MEX3C is necessary for normal postnatal growth and enhances the expression of local bone Igf1 expression. Here we report the pivotal role of Mex3c in energy balance regulation. Mex3c mutation caused leanness in both heterozygous and homozygous transgenic mice, as well as a more beneficial blood glucose and lipid profile in homozygous transgenic mice, in both sexes. Although transgenic mice showed normal food intake and fecal lipid excretion, they had increased energy expenditure independent of physical activity. Mutant mice had normal body temperature, Ucp1 expression in brown adipose tissue, and muscle and liver fatty acid oxidation. Mex3c is expressed in neurons and is detectable in the arcuate nucleus, the ventromedial nucleus, and the dorsomedial nucleus of the hypothalamus. Mex3c was not detected in NPY or POMC neurons but was detected in leptin-responsive neurons in the ventromedial nucleus. Mex3c and Leptin double mutant mice were growth retarded and obese and had blood profiles similar to those of ob/ob mice but showed none of the steatosis observed in ob/ob mice. Our data show that Mex3c is involved in energy balance regulation.
High levels of HIV‐1 replication show a clear correlation with downmodulation of Bcl‐2 protein in peripheral blood lymphocytes of HIV‐1‐seropositive subjects

Peripheral blood lymphocytes (PBLs) from 51 HIV‐1‐seropositive subjects with different levels of HIV‐1 replication and 20 healthy blood donors were examined for the expression of the antiapoptotic Bcl‐2 protein. All the plasma samples from HIV‐1 patients were characterized for the presence of HIV‐1 p24 and HIV RNA viral load. Bcl‐2 protein expression in fresh peripheral blood lymphocytes was studied by different tests, including Western blot and indirect immunofluorescence techniques. Direct immunofluorescence staining, revealed by flow cytometry, was applied to quantify the number of specific anti‐Bcl‐2 antibody epitope binding sites, thus extrapolating the relative number of Bcl‐2 into the cells. The results indicate that the expression of Bcl‐2 protein is significantly lower in peripheral blood lymphocytes of HIV‐1‐seropositive patients showing high levels of viral replication, detected by means of HIV‐1 p24 and RNA viral load, with respect to HIV‐1 patients with low levels of virus replication and healthy blood donors. The clear‐cut inverse correlation between viral replication and Bcl‐2 expression reinforces the view that HIV‐1‐mediated apoptosis probably represents a key mechanism in AIDS pathogenesis. J. Med. Virol. 56:66–73, 1998. © 1998 Wiley‐Liss, Inc.
The capacity of the white Gaussian multiple access channel with feedback

Since the appearance of [10] by Gaarder and Wolf, it has been well known that feedback can enlarge the capacity region of the multiple access channel. In this paper a deterministic feedback code is presented for the two-user Gaussian multiple access channel, which is shown to allow reliable communication at all points inside a region larger than any previously obtained. An outer bound is given which is shown to coincide with the achievable region, thus yielding the capacity region of this channel exactly.
Fuzzy sampled-data H∞ filtering for systems with time-varying delays and variable sampling periods

The sampled-data H∞ filtering for a Takagi-Sugeno (T-S) model-based fuzzy system with an interval time-varying state delay and a variable sampling period is considered. A new Lyapunov-Krasovskii functional is constructed by utilizing more information about the system's current state and the delayed state. Based on the new Lyapunov-Krasovskii functional and a novel inequality bounding technique, a suitable sampled-data fuzzy H∞ filter is designed to ensure the asymptotic stability and prescribed H∞ attenuation level of the filter error system. A numerical example and a modified continuous stirred tank reactor (CSTR) system are given to illustrate the effectiveness of the proposed method.
Case series: TRAP sequence

Abstract TRAP (twin reversed arterial perfusion) sequence / acardiac twinning is a rare anomaly that occurs in monozygotic monochorionic twins with an incidence of 1% and in 1 in 35,000 pregnancies overall. The anomalous twin appears as a heterogeneous mass, simulating a teratoma or intrauterine fetal demise. As the normal twin faces increased morbidity and mortality, antenatal diagnosis with gray-scale examination, and Doppler confirmation of the diagnosis of TRAP sequence in twin pregnancies, aids in proper prenatal management. We report two cases of TRAP sequence that we encountered over a single month, with the two cases having different outcomes.
Extremum-Seeking Control of ABS Braking in Road Vehicles With Lateral Force Improvement

An ABS control algorithm based on extremum seeking is presented in this brief. The optimum slip ratio between the tire patch and the road is searched online without having to estimate road friction conditions. This is achieved by adapting the extremum-seeking algorithm as a self-optimization routine that seeks the peak point of the tire force-slip curve. As an additional novelty, the proposed algorithm incorporates driver steering input into the optimization procedure to determine the operating region of the tires on the “tire force”-“slip ratio” characteristic-curve. The algorithm operates the tires near the peak point of the force-slip curve during straight line braking. When the driver demands lateral motion in addition to braking, the operating regions of the tires are modified automatically, for improving the lateral stability of the vehicle by increasing the tire lateral forces. A validated, full vehicle model is presented and used in a simulation study to demonstrate the effectiveness of the proposed approach. Simulation results show the benefits of the proposed ABS controller.
Mitochondrial Translocator Protein (TSPO) Function Is Not Essential for Heme Biosynthesis*

Function of the mammalian translocator protein (TSPO; previously known as the peripheral benzodiazepine receptor) remains unclear because its presumed role in steroidogenesis and mitochondrial permeability transition established using pharmacological methods has been refuted in recent genetic studies. Protoporphyrin IX (PPIX) is considered a conserved endogenous ligand for TSPO. In bacteria, TSPO was identified to regulate tetrapyrrole metabolism and chemical catalysis of PPIX in the presence of light, and in vertebrates, TSPO function has been linked to porphyrin transport and heme biosynthesis. Positive correlation between high TSPO expression in cancer cells and susceptibility to photodynamic therapy based on their increased ability to convert the precursor 5-aminolevulinic acid (ALA) to PPIX appeared to reinforce this mechanism. In this study, we used TSPO knock-out (Tspo−/−) mice, primary cells, and different tumor cell lines to examine the role of TSPO in erythropoiesis, heme levels, PPIX biosynthesis, phototoxic cell death, and mitochondrial bioenergetic homeostasis. In contrast to expectations, our results demonstrate that TSPO deficiency does not adversely affect erythropoiesis, heme biosynthesis, bioconversion of ALA to PPIX, and porphyrin-mediated phototoxic cell death. TSPO expression levels in cancer cells do not correlate with their ability to convert ALA to PPIX. In fibroblasts, we observed that TSPO deficiency decreased the oxygen consumption rate and mitochondrial membrane potential (ΔΨm) indicative of a cellular metabolic shift, without a negative impact on porphyrin biosynthetic capability. Based on these findings, we conclude that mammalian TSPO does not have a critical physiological function related to PPIX and heme biosynthesis.
GLUCONEOGENIC SUPPLEMENTS DO NOT AFFECT PRODUCTION, REPRODUCTIVE TRAITS AND BLOOD METABOLITE OF HOLSTEIN COWS DURING THE TRANSITION PERIOD

O uso de produtos gliconeogenicos para vacas leiteiras no periodo de transicao tem gerado respostas contraditorias na literatura, dificultando a sua recomendacao. O objetivo deste experimento foi avaliar a suplementacao de propileno glicol (PG), propionato de calcio (PC) e "Dairy Power Drench®" (DR) no periodo de transicao de vacas leiteiras sobre a variacao do escore da condicao corporal (ECC), peso vivo (PV), producao de leite (PL), eficiencia reprodutiva e concentracao plasmatica dos acidos graxos livres (AGL). Foram utilizadas 165 femeas de dois rebanhos comerciais. Os tratamentos foram: C- Controle; DR- 3 aplicacoes de "Dairy Power Drench®" no pos-parto; PC- 500 g diarios de PC e PG- 500 mL diarios de PG, ate o 50o dia pos-parto, em media. As causas de variacao estudadas foram efeito de tratamento e efeito dos blocos formados em funcao da fazenda e do numero de partos. Nao foi observado efeito de interacao de tempo (semanas) × tratamento ou de tratamento sobre ECC. Entretanto, houve efeito quadratico de tempo. Para o PV e variacao diaria de PV nao foi observado efeito dos tratamentos, nem interacao entre tempo × tratamento. Entretanto, apresentaram efeito quadratico de tempo. Para PL, houve efeito de interacao tempo × tratamento. Porem, dentro de cada semana, as possiveis diferencas nao foram detectadas. Os tratamentos nao afetaram os parâmetros de eficiencia reprodutiva. Encontraram-se, em media, 69,5 dias para o aparecimento do primeiro cio, 2,23 servicos por concepcao e 172,6 dias para o periodo de servico. As concentracoes medias dos AGL foram de 376,6 mmol L-1, nao se observando efeitos de tempo × tratamento ou de tratamento. Porem, apresentaram efeito linear de tempo, decrescendo 48,2 mmol L-1 por semana.
Le vocabulaire de Jean Giraudoux. Structure et évolution.

Depouillement systematique des 670.000 mots qui constituent le corpus de Giraudoux, ainsi que des 37 millions d'occurrences qui representent la langue litteraire de l'epoque, toile de fond sur laquelle se detache l'originalite giralducienne. La methode est empruntee pour l'essentiel aux maitres de la statistique linguistique, Herdan, Guiraud et Muller, et permet ici une des premieres applications faites en France de l'analyse factorielle dans le domaine litteraire et linguistique. Pierre Guiraud declarait a la lecture du manuscrit : "Cette premiere etude, entierement automatisee d'une oeuvre dans sa totalite, introduisant des criteres methodologiques originaux, fait de M. Brunet le specialiste du traitement par ordinateur des problemes linguistiques, et sa these constituera un ouvrage de reference".
Using fMRI to Examine Central Auditory Plasticity

During the last two decades or so, auditory neuroscience has made significant progress in understanding the functional organization of the auditory system in both normal-hearing listeners, patients with sensorineural hearing impairments and/or tinnitus, and following cochlear implantation. Modern brain imaging techniques have made an enormous contribu‐ tion to that progress by enabling the in vivo study of human central auditory function. Since its introduction, magnetic resonance imaging (MRI) has evolved to become one of the most influential methods for investigating non-invasive human brain structure and function. Functional MRI (fMRI) has become the tool of choice for addressing many research questions concerning central auditory plasticity. First, fMRI has good spatial sensitivity and specificity and so can be used to map auditory responses with reasonably fine topographic detail (Logothetis et al., 2001). Second, fMRI is suitable for research use with children, as well as adults. Third, since multiple observations can be made on the same individual, fMRI permits the investigation of longer-term dynamic processes, such as functional plasticity after disease, damage, retraining or therapy. Finally, the need for averaging data across individuals is reduced, further improving the accuracy with which activations can be mapped onto subjectspecific brain structure (e.g. Talavage et al., 2004). Despite these advantages, there are signif‐ icant issues using this technique in certain clinical populations, such as individuals with a cochlear implant (CI). Subsequently, to investigate the effects of CIs on brain reorganization, it is necessary to consider alternative functional imaging methods, such as electroencephalog‐ raphy (e.g. Debener et al., 2008). Moreover, the high level of the scanner acoustic noise can have detrimental effects on central auditory function, patient anxiety and verbal communica‐ tion between patient and scanner operator (Mechefske et al., 2002). In terms of central auditory function, the scanner acoustic noise can induce increases in the fMRI response of the auditory cortex as well as interfere with the perception of externally presented sound stimuli (Edmister et al., 1999; Hall et al., 1999).
Generalized PIC Detector for Distributed STBC under Quasi-Synchronization

In this paper, we propose a Generalized Parallel Interference Cancelation (G-PIC) approach for the detection of D-STBC under Quasi-Synchronization in the case of any number of relay nodes with just statistical information about time misalignment. While as, most researches assume perfect synchronization between the relay nodes for the detection of D-STBC which is hard to achieve. This approach proved to be very effective to mitigate the degradation in the system performance due to the imperfect synchronization. The numerical simulations, for the proposed approach, showed that in just three iterations we can achieve performance close to the D-STBC with perfect synchronization.
Rule-Based Service Oriented Business Network Process Realization in Dynamic Virtual Enterprises

Rapidly changing business atmosphere and turbulent market conditions cause enterprises to collaborate with each other to accomplish business opportunities. Meanwhile, dynamic virtual enterprise (DVE) as a response for agile collaboration of various enterprises is under focus of both academia and practice for years. The dream of highly dynamic VEs comes true with the aim of semi-automatic realization of DVE’s Business Network Processes (BNPs). This paper is to propose a framework and related tools and techniques to constitute BNP, as a main building block of DVEs. The framework namely Service Oriented Business Network Process (SOBNP) Realization enjoys three salient characteristics: a) it has been adjusted to the end-user (i.e. the process owner) who has no deep knowledge of computer science; b) it utilizes business rules to realize SOBNP semi-automatically; and c) it leverages both syntactic and semantic techniques for efficient partner selection. A simplified example is used upon for better illustrating our approach throughout the paper. Moreover, the article discusses preliminary implementation of prototype system.
Excitation spectrum of Heisenberg spin ladders.

Heisenberg antiferromagnetic spin ladders'' (two coupled spin chains) are low-dimensional magnetic systems which for [ital S]=1/2 interpolate between half-integer-spin chains, when the chains are decoupled, and effective integer-spin one-dimensional chains in the strong-coupling limit. The spin-1/2 ladder may be realized in nature by vanadyl pyrophosphate, (VO)[sub 2]P[sub 2]O[sub 7]. In this paper we apply strong-coupling perturbation theory, spin-wave theory, Lanczos techniques, and a Monte Carlo method to determine the ground-state energy and the low-lying excitation spectrum of the ladder. We find evidence of a nonzero spin gap for [ital all] interchain couplings [ital J][sub [perpendicular]][gt]0. A band of spin-triplet excitations above the gap is also analyzed. These excitations are unusual for an antiferromagnet, since their long-wavelength dispersion relation behaves as ([ital k][minus][ital k][sub 0])[sup 2] (in the strong-coupling limit [ital J][sub [perpendicular]][much gt][ital J], where [ital J] is the in-chain antiferromagnetic coupling). Their band is folded, with a minimum energy at [ital k][sub 0]=[pi], and a maximum between [ital k][sub 1]=[pi]/2 (for [ital J][sub [perpendicular]]=0) and 0 (for [ital J][sub [perpendicular]]=[infinity]). We also give numerical results for the dynamical structure factor [ital S]([ital q],[omega]), which can be determined in neutron scattering experiments. Finally, possible experimental techniques for studying the excitationmore » spectrum are discussed. « less
In Vivo Cardiac Diffusion-Weighted Magnetic Resonance Imaging: Quantification of Normal Perfusion and Diffusion Coefficients With Intravoxel Incoherent Motion Imaging

ObjectivesDiffusion-weighted imaging (DWI) and the introduction of the intravoxel incoherent motion (IVIM) model have provided a unique method for evaluating perfusion and diffusion within a tissue without the need for a contrast agent. Despite its relevance, cardiac DWI has thus far been limited by low b values because of signal loss induced by physiological motion. The goal of this study was to develop a methodology for estimating IVIM parameters of in vivo cardiac magnetic resonance imaging using an efficient DWI acquisition framework. This was achieved by investigating various acquisition strategies (principal component analysis [PCA] filtering and temporal maximum intensity projection [PCATMIP] and single trigger delay [TD]) and fitting methods. Material and MethodsSimulations were performed on a synthetic dataset of diffusion-weighted signal intensity (SI) to determine the fitting method that would yield IVIM parameters with the greatest accuracy. The required number of b values to correctly estimate IVIM parameters was also investigated. Breath-hold DWI scans were performed for 12 volunteers to collect several TD values during diastole. Thirteen b values ranging from 0 to 550 s/mm2 were used. The IVIM parameters derived using the data from all the acquired TDs (PCATMIP technique) were compared with those derived using a single acquisition performed at an optimized diastolic time point (1TD). ResultsThe main result of this study was that PCATMIP, when combined with a fitting model that accounted for T1 and T2 relaxation, provided IVIM parameters with less variability. However, an acquisition performed with 1 optimized diastolic TD provided results that were as good as those provided using PCATMIP if the R-R variability during the acquisition was sufficiently low (±5%). Furthermore, the use of only 9 b values (that could be acquired in 2 breath-holds), instead of 13 b values (requiring 3 breath-holds), was sufficient to determine the IVIM parameters. ConclusionsThis study demonstrates that IVIM is technically feasible invivo and reports for the first time the perfusion fraction, f, and the diffusion coefficients, D and D*, for the cardiac DWI of healthy volunteers. Motion-induced signal loss, which is the main problem associated with cardiac DWI, could be avoided with the combined use of sliding acquisition during the cardiac cycle and image postprocessing with the PCATMIP algorithm. This study provides new perspectives for perfusion imaging without a contrast agent and demonstrates that IVIM parameters can act as promising tools to further characterize microvascular abnormalities or dysfunction.