Miracle-dz/UniFAR-FTUs huggingface dataset:
Knowledge, Motivations and Concerns about Participation in Breast Cancer Clinical Trials in Puerto Rico.

Background Clinical trials (CT) in breast cancer have been crucial for new treatment discoveries. While participation in cancer CT is low, minorities are particularly underrepresented. This study aimed to identify factors influencing the participation in CTs based on the experiences of Latina breast cancer survivors in Puerto Rico (PR), especially their CT knowledge, motivations, and concerns. Method Focus groups (FG) were conducted by two social workers and the University of Puerto Rico/MD Anderson Community Health Educator. Participants were stratified into two subgroups: a) women with CT experience and b) those without CT experience. Seven FG were completed among breast cancer survivors (n=34) at two hospitals located in Caguas and San Juan, PR. Results Our findings showed that participants expressed a basic knowledge and understanding of clinical trials. Motivations to participate included a desire to help others, non-monetary incentives to participation, self-benefits, readiness to participate based on the phases of illness, and enhanced relationships with the clinical trial recruitment team. Regardless of their previous experience with CTs, participants expressed concerns about participation including limited of knowledge about trial procedures and results, and lack of transportation, childcare, and support from family. Recommendations The barriers and motivations identified for CT participation are modifiable and best targeted using a multidisciplinary approach. Social workers could play a potential role in participant recruitment and retention by clarifying research protocols to potential participants, as well as conducting CT. Our findings can help enhance capacity and training efforts for health professionals involved in CT recruitment and retention in culturally-relevant ways.
Expertise, politics and public opinion at the crossroads of the European Commission’s decision-making: The case of Glyphosate.

With the growing politicisation of European Union (EU) integration, the European Commission is increasingly facing a tension between technocratic and responsive decision-making. How does this tension play out in the process of supranational implementation under comitology rules? We argue that the tension between the Commission´s role as a technocrat and as a responsive bureaucrat takes place during the implementation process when the issue at stake becomes politicised. We test our argument through the analysis of the Glyphosate renewal procedure (2015-2017). We process-trace the case by means of semi-structured interviews, media and document analysis. We find that with the increase of issue visibility and subsequent politicisation, the Commission progressively abandons a purely technocratic behaviour. First, it puts in place political strategies such as delays and blame-shifting to release itself from the burden of unpopular decisions. Secondly, it seeks to respond to concerns expressed by consumers by proposing compromise-based measures closer to public interest. Ultimately, we show how the outcome of the policy process is mediated by politicisation and characterised by a shift from technocratic to responsive decision making.
The Assessment of Gender Pronouns in Relation to Gender Stereotypes and Sexism

All languages distinguish between genders to a varying degree. Gender stereotypes in language are often gender-specific, where agentic words are considered as male and communal words are considered as female. Studies have found that countries with gendered languages express more sexism, compared to countries with natural gender or gender-neutral languages. The following study will investigate the assessment of the three gendered pronouns in the Swedish language, by the use of gender stereotypes (i.e., agentic and communal adjectives). It is also of interest to assess the gendered pronouns and gender stereotypes in relation to sexism or sexist beliefs. No relationship was found between the gendered pronouns and the gender stereotypes in this study. However, sexism influenced the assessment of the gendered pronouns, by describing the female pronoun as more communal, compared to the gender-neutral pronoun hen. No relationship was found between sexism and the assessment of the male pronoun, compared to the gender-neutral pronoun hen. In the future, more research is needed to determine the actual linguistic importance of the gendered pronouns and their potential impact on gender equality.
An Overlapping Generations Model with Two Periods and Perfect Foresight

The overlapping generations (OLG) model together with the Ramsey model are the main models used in macroeconomics. The Ramsey model is said to be an optimal macroeconomic model because the general equilibrium of the decentralized economy verifies the First Welfare Theorem (FWT) (= satisfies the Pareto optimal criterion). The specificity of the OLG model is its demographic structure: in each period, there is a generation of young and a generation of old agents trading in the markets. Apart from their age difference, these two groups are distinguished by their resources. The young live on labour income while the old live on capital income (= their saving + the interest on their saving). In an OLG model, the general equilibrium of the decentralized economy may not satisfy the FWT. This therefore leaves room for public intervention to improve the welfare of economic agents (= Second Welfare Theorem (SWT)).
Broadband Eight-Antenna Array Design for Sub-6 GHz 5G NR Bands Metal-Frame Smartphone Applications

A multiple-input–multiple-output (MIMO) antenna array for broadband 5G new radio (5G NR) metal-frame smartphone applications is proposed. The MIMO antenna array is realized by loading eight identical antennas (Ant1–Ant8) into the metal frame of the smartphone to form an eight-antenna array for the sub-6 GHz 8 × 8 MIMO system. Each antenna element is a slot antenna type that is composed of an L-shaped open slot and a 50 Ω microstrip feedline, and good impedance matching in the upper frequency band can be achieved by loading a tuning stub to the feedline. The 10 dB impedance bandwidth of the proposed eight-antenna array can cover the 5G NR Bands n77/n78/n79 and wireless local area network (WLAN) 5 GHz band. Besides demonstrating desirable antenna efficiency of 50%–82% and envelope correlation coefficient of <0.11, the isolations between adjacent array elements are also >12 dB. At 20 dB signal-to-noise ratio (SNR), the calculated peak channel capacity of the proposed eight-antenna array applied to an 8 × 8 MIMO system is 43.93 b/s/Hz.
Gold Nanoparticle Uptake in Tumor Cells: Quantification and Size Distribution by sp-ICPMS

Gold nanoparticles (AuNPs) are increasingly studied for cancer treatment purposes, as they can potentially improve both control and efficiency of the treatment. Intensive research is conducted in vitro on rodent and human cell lines to objectify the gain of combining AuNPs with cancer treatment and to understand their mechanisms of action. However, using nanoparticles in such studies requires thorough knowledge of their cellular uptake. In this study, we optimized single particle ICPMS (sp-ICPMS) analysis to qualify and quantify intracellular AuNP content after exposure of in vitro human breast cancer cell lines. To this aim, cells were treated with an alkaline digestion method with 5% TMAH, allowing the detection of gold with a yield of 97% on average. Results showed that under our experimental conditions, the AuNP size distribution appeared to be unchanged after internalization and that the uptake of particles depended on the cell line and on the exposure duration. Finally, the comparison of the particle numbers per cell with the estimates based on the gold masses showed excellent agreement, confirming the validity of the sp-ICPMS particle measurements in such complex samples.
PE ] 2 1 A pr 2 01 6 The biased evolution of generation time

Many life-history traits, like the age at maturity or adult longevity, are important determinants of the generation time. For instance, semelparous species whose adults reproduce once and die have shorter generation times than iteroparous species that reproduce on several occasions. A shorter generation time ensures a higher growth rate in stable environments where resources are in excess, and is therefore a positively selected feature in this (rarely met) situation. In a stable and limiting environment, all combination of traits (or strategies) that produce the same number of viable offspring on average are strictly neutral even when their generation times differ. We first study the evolution of life-history strategies with different generation times in this context, and show that those with the longest generation time represent the most likely evolutionary outcomes. Indeed, strategies with longer generation times generate fewer mutants per time unit, which makes them less likely to be replaced within a given time period. This ‘turnover bias’ inevitably exists and favors the evolution of strategies with long generation times. Its real impact, however, should depend on the strength and direction of other evolutionary forces; selection for short generation times, for instance, may oppose turnover bias. Likewise, the evolutionary outcome depends on the strength of such selection and population size, comparably to other biases acting on the occurrence of mutations. Introduction Generation time is a major feature of organisms, whose evolution is usually considered through the prism of life-history strategies – i.e. combinations of traits that often impact generation time, like adult survival or the age of reproductive maturity. Why there exist populations or species with long generation times can be intriguing, as in a stable non-limiting environment the most evolutionary successful strategy is the one that grows most rapidly [1, 2]. Life-history strategies that reduce generation time – “fast strategies” hereafter – thus benefit from a selective advantage over “slow strategies” in this context. Whenever population growth is limited, however, the advantage to a fast strategy may vanish. In this context, the selective advantage of a mutant is given by the number of viable offspring it is expected to produce, also known as its net reproductive rate R0 [3–5]: whether the mutant breeds shortly or not, or produces few or many litters, is not seen by selection. Many life-history traits influence both the generation time and the R0, such that their evolutionary dynamics are often thought to be dominated by selection [6]. Nonetheless, heritable changes in life-history traits may not necessarily be filtered stringently by selection because negative relationships (trade-offs) exist between these traits and restrict their ability to vary independently [7]. Life-history strategies are indeed distributed along trade-offs whose shapes are often sufficient to predict which strategy, if any, is the most likely to evolve by selection.
Reproductive biology of the mackerel scad Decapterus macarellus from Cabo Verde and the implications for its fishery management

The mackerel scad Decapterus macarellus is of great social and economic importance to Cabo Verde citizens; however, in recent years catches have shown an unexplained decline. The harvest is regulated by way of a minimum legal size and a seasonal closure, with both measures based on the results of reproductive studies that did not consider the microscopic characteristics of the gonads. This study aimed to analyse the gonads microscopically in order to classify the sexual development stage of individuals and to estimate the size at first maturity and the reproductive season. This information was then used to analyse the match between the reproductive parameters and the management measures. The samples comprised 284 females (20–36 cm fork length [FL]) and 85 males (21–35 cm FL). The annual variation in gonadosomatic index and the monthly frequencies of mature phases suggest that the reproductive season occurs from March to October, with two spawning peaks, one in March and another from July to October. The current seasonal closure (from July to September) covers the main reproductive period. However, the species has a long spawning period and the timing of peaks can vary between years; hence, a reassessment of this management measure is recommended. The sizes at first maturity were estimated at 24.1 cm FL for females, and 26.6 cm FL for males. These values are higher than the minimum legal size (20 cm FL) currently established for management of the species at Cabo Verde; thus, we strongly recommend an increase in the minimum legal size in an attempt to reduce catches of immature individuals.
A Stationary Reference Frame Current Control Algorithm for Improvement of Transient Dynamics of a Single Phase Grid Connected Inverter

This paper proposes a stationary reference frame current control algorithm for a single-phase grid-connected inverter (GCI) for improvement of transient dynamic performance. Disturbance, i.e., grid voltage in a target system, is estimated using a stator current observer, and the estimated disturbance is applied to a current controller for implementation of disturbance rejection control (DRC). In the proposed current control algorithm, the disturbance rejection control algorithm is applied to reduce the overcurrent occurring in the single-phase grid-connected inverter when grid faults happen. In this paper, the AC phase current of a single-phase inverter is controlled, instead of the current vector, which is a DC signal. To compensate for the drawbacks of controlling the AC phase current, such as phase lag and steady-state error, command feedforward control is also applied in the proposed control system. The proposed control algorithm is mathematically derived and represented in transfer functions and implemented via simulation and experiment.
Therapy with Pegylated Interferon or Combined with Cryosurgery in Condyloma Acuminata. Phase iii Clinical Trial

Background: The continuous recurrence of condyloma acuminata makes the constant search for necessary therapeutic alternatives. Patients and method: To evaluate the therapeutic efficacy and safety of pegylated interferon, alone or adjuvant for cryosurgery, in the condyloma acuminata an open clinical trial was carried out on 30 patients of the "Hermanos Ameijeiras" hospital, who were randomized to receive for 6 weeks (group A) only fortnightly cryosurgery, (group B) subcutaneous pegylated interferon, once a week, associated with fortnightly cryosurgery application or (group C) only subcutaneous pegylated interferon, once a week. The main variable was the percentage of recurrence at one year of follow-up, evaluated quarterly. There was also a rigorous control of adverse events. Results: At the end of the treatment 8/10 (80%) patients from group A, 10/10 (100%) from group B and 9/10 (90%) from group C were left without injuries. During the follow-up, none of the patients who received pegylated interferon, alone or adjuvant to cryosurgery, had recurrences; while 100% of patients who received cryosurgery as exclusive treatment relapsed (p <0.000). The most frequent events were local burning (100%) due to cryosurgery and fever (6.6%), headache (6.6%), myalgia (3.3%) and malaise (3.3%) due to interferon. Conclusion: Pegylated interferon alone or adjuvant to cryosurgery provides benefits for the quality of life of patients, with absolute and relative reduction of a 100% of the risk of recurrence.
FAMILY ADVERSITY FACTORS AND EXTERNAL RESOURCES OF RESILIENCE IN A ONE-YEAR FOLLOW-UP

Objectives: External resources of resilience along with internal assets facilitate the healthy development of adolescents and eventually contribute to overcoming adversity. Therefore, it is crucial to examine the factors which enhance or reduce external resources of resilience. The main goal of this study is to explore the role of adversity factors: adolescents – parental conflict, antagonism and punishment and family structure in explaining perceived external resources of resilience – school meaningful participation and community meaningful participation in a one-year follow-up. Methods: 146 (49% girls) adolescents (T1 mean age=13.51) participated in a repeated measures design with a 12-month follow-up. External resources of resilience (School meaningful participation (SMP) and Community meaningful participation (CMP)) were measured by the RYDM questionnaire. Parental conflict, antagonism and punishment were assessed by the NRI-SPV questionnaire separately for the mother and father. The family structure was dichotomized (both biological parents vs. other). Results: The linear regression revealed that having something other than biological family is associated with lower SMP and CMP over the year while controlling for SMP and CMP at T1. Moreover, higher punishment from the father is associated with lower SMP while higher antagonism with the mother is associated with higher CMP after one year. In addition, the findings confirmed a moderation effect of gender and father punishment on SMP. This shows that the probability of lower SMP at T2 is higher for boys with a higher level of punishment by the father at T1. Conclusion: Family structure is a key factor in contributing to lower external resources of resilience. Father punishment negatively contributes to SMP, although not CMP. Mother antagonism positively contributes to CMP but not SMP. The moderation effect of gender between father punishment and SMP implies a greater sensitivity of boys towards father punishment and a potential inhibition effect on participation at school in comparison to girls. Interestingly, antagonism with the mother contributes to higher CMP which reveals the potential self-protection mechanism of adolescents in compensating antagonism with the mother for meaningful participation in different environments such as the community. However, there is a failure to compensate at school when the punishment from the father is greater.
Robust Yaw Stability Controller Design and Hardware-inthe-Loop Testing for a Road Vehicle Bilin

Unsymmetrical loading on a car like μ-split braking, side wind forces, or unilateral loss of tire pressure results in unexpected yaw disturbances that require yaw stabilization either by the driver or by an automatic driver-assist system. The use of two-degrees-of-freedom control architecture known as the model regulator is investigated here as a robust steering controller for such yaw stabilization tasks in a driver-assist system. The yaw stability-enhancing steering controller is designed in the parameter space to satisfy a frequency-domain mixed sensitivity constraint. To evaluate the resulting controller design, a real-time hardware-in-the-loop simulator is developed. Steering tests with and without the controller in this hardware-in-the-loop setup allow the driver to see the effect of the proposed controller to improve vehicle-handling quality. The hardware-in-the-loop simulation setup can also be used for real-time driver-in-the-loop simulation of other vehicle control systems.
Tunable Stable Levitation Based on Casimir Interaction between Nanostructures

Quantum levitation enabled by repulsive Casimir force has been a desire due to the potential exciting applications in passive-suspension devices and frictionless bearings. In this paper, dynamically tunable stable levitation is theoretically demonstrated based on the configuration of dissimilar gratings separated by an intervening fluid using exact scattering theory. The levitation position is insensitive to temperature variations and can be actively tuned by adjusting the lateral displacement between the two gratings. This work paves a way toward applying quantum Casimir interactions into macroscopic mechanical devices working in a noncontact and low-friction environment for controlling the position or transducing lateral movement into vertical displacement at the nanoscale. PACS numbers: 42.50. Lc, 03.70. +k, 85.85. +j 1 Corresponding author: Telephone: (01) 404-385-4225; E-mail: zhuomin.zhang@me.gatech. edu.
Ways to Use Prosody in the Detection of Actionable Information in Radio Broadcasts

Finding actionable information in unstructured audio collections is a challenge, especially for low resource languages, which may lack not only speech processing tools, but also enough data to train such tools in the normal way. This paper explores alternative ways to detect segments containing actionable information in radio news, using prosody. Examining the prosody of attributes such as urgency, in news broadcasts in six languages, we found consistently correlating prosodic features. Using these for prediction gave a leave-one-language-out AUC of 0.64, and also good results for previously unseen languages.
Co-creation strategy in peer-to-peer accommodation in Bandung tourism context

Abstract Collaborative economy refers to social and economic sharing activities that make entities (customer and peer provider) in-service ecosystem can access services through technology or digital platform. This research aims to give a better understanding of activities and interaction between entities that can potentially elevate the existence of peer-to-peer (P2P) accommodation in Indonesia. Although research regarding the collaborative economy has been accelerating, there has not been a formal conceptualization of interaction from a broadening perspective as a service ecosystem in the context of co-creation. Preliminary study becomes crucial and relevant with the raising of the collaborative economy, based on the consideration that no previous research is considered to be able to explain the dynamics of interaction by using a perspective of Service-Dominant Logic (S-D Logic). This study seeks to answer two research questions, what interactions occur outside consumers, peer providers, platform providers, and how co-creation might be created in the P2P service ecosystem. This conceptual paper draws on the interaction from the perspective of co-creation between entities and stakeholders as a lens by using the systematic-qualitative approach. In general, this study uses the Soft System Methodology (SSM) precisely defining an unstructured situation in the real world. This study tries to initiate the development of phases of co-creation between entities in the service ecosystem. The outcomes of this study enrich the body of knowledge of service science, especially on the way to apply the framework value co-creation. The development of a better service ecosystem across particular engagement remains critical.
A Reconstructed S-LCC Topology With Dual-Type Outputs for Inductive Power Transfer Systems

In inductive power transfer (IPT) applications, load-independent output has become more popular. This letter proposes a reconstructed S-LCC topology with dual-type outputs, which can realize constant current (CC) output and constant voltage (CV) output simultaneously. The proposed reconstructed S-LCC topology uses the same number of passive components, inductor or capacitor, as conventional S-LCC topology while provides dual-type outputs, which results in reduced cost and size. Such dual-type outputs could be treated as two independent output ports without using any decoupling methods, which can simplify the parameter design significantly. The circuit model of the proposed reconstructed S-LCC topology is analyzed in detail. Comparison between the proposed reconstructed S-LCC topology and multicoil structure is performed. Experimental prototypes with 300V/1.5 kW CV output and 10A/1 kW CC output are fabricated to verify the feasibility of the proposed topology.