Miracle-dz/UniFAR-FTUs huggingface dataset:
Compact Waveguided Metamaterials for Suppression of Mutual Coupling in Microstrip Array

In this paper, suppression of mutual coupling is achieved using compact waveguided metamaterials (WG-MTMs) in between elements of a densely packed microstrip array. Both the E-plane internally folded complementary split ring resonator and the H-plane internally folded complementary split ring resonator are employed to reduce the mutual coupling between adjacent elements. Coupling suppression of 18 dB and 9 dB, for elements in the E-plane and H-plane, respectively, is demonstrated. Due to the compact size of the waveguided metamaterials, the edge-to-edge separation between elements is kept at only 0. 093λ0. With the same element spacing, a 2 × 2 array is also simulated with compact WG-MTMs. The proposed structure reduces the array size and enables the implementation of compact Multiple-Input-Multiple-Output systems.
Delta and gamma oscillations in operculo-insular cortex underlie innocuous cold thermosensation

Using magnetoencephalography, we identified spatiotemporal features of central cold processing, with respect to the time course, oscillatory profile, and neural generators of cold-evoked responses in healthy human volunteers. Cold thermosensation was associated with low- and high-frequency oscillatory rhythms, both originating in operculo-insular regions. These results support further investigations of central cold processing using magnetoencephalography or EEG and the clinical utility of cold-evoked potentials for neurophysiological assessment of cold-related small-fiber function and damage.
Efficient hydroxyproline production from glucose in minimal media by Corynebacterium glutamicum

The efficient coupling of biotransformation steps to an existing fermentation pathway is an interesting strategy to expand the product portfolio of Corynebacterium glutamicum as whole‐cell biocatalyst. This is especially challenging if the biotransformation step comprises a direct link to central metabolism, as in the case of α‐ketoglutarate‐dependent oxygenase catalysis. Aiming at trans‐4‐hydroxy‐L‐proline (Hyp) production from glucose in a minimal medium, the proline‐4‐hydroxylase gene from Dactylosporangium sp. strain RH1 was introduced into a proline‐producing, isoleucine‐bradytroph C. glutamicum strain. The production of proline was found to be induced by isoleucine limitation. Proline and Hyp production were found to depend differently on isoleucine limitation. Severe isoleucine limitation was shown to result in proline accumulation and low hydroxylation rates both in batch and continuous cultivation set‐ups. The investigation of different steady states with various glucose/isoleucine molar ratios revealed that optimal conditions for Hyp production are met around a molar ratio of 46:1, where isoleucine limitation is sufficient to trigger proline production but the hydroxylation rate is high enough to convert the majority of formed proline to Hyp. A high cell‐density fed‐batch set‐up was designed, capable of producing 7.1 g L−1 of Hyp from glucose in 23 h with 98.5% conversion of proline to Hyp. Reaction engineering, specifically the fine‐tuning of the glucose/isoleucine concentration ratio, enabled control of the fermentation profile and thus the accumulation of the desired product Hyp from glucose in minimal and defined media. Biotechnol. Bioeng. 2015;112: 322–330. © 2014 Wiley Periodicals, Inc.
EMMT: Multiflow wireless multicasting transmission for IEEE 802.11

In Wireless multimedia services have a major applications of next generation wireless networks to the efficient utilization of network resources when a channel becomes saturated that time develop the number of concurrent multimedia flows to the network. How, In the flow scheduling and the channel aggregation policy are both the single-hop and multi-hop wireless networks with the motivation of the trade-off between the multiple flow transmission and limited channel resources. So to develop the number of performance and data flows are guaranteed increase in multimedia flows, it based on the dynamic states of wireless channels and the profiles of multimedia flows, we following that above two policies are fully utilize the performance gap to schedule concurrent flows for transmission in turn and aggregate multiple channels' residual capacities for useful flow transmissions. We then design a novel algorithm - efficient multi-flow multicast transmission (EMMT) - to apply the proposed policies to practical wireless multimedia multicast applications. So we can increase the data flows in multimedia in deferent path. Here we use ns2 simulations to evaluate the policies and the EMMT algorithm. This type of process is proved that the resource allocation of the new technology and also compared with Channel diversity transmission method. With the further development of quality of service schemes on relating user experience to QoS.
Synaptic Protein Degradation Underlies Destabilization of Retrieved Fear Memory

Reactivated memory undergoes a rebuilding process that depends on de novo protein synthesis. This suggests that retrieval is dynamic and serves to incorporate new information into preexisting memories. However, little is known about whether or not protein degradation is involved in the reorganization of retrieved memory. We found that postsynaptic proteins were degraded in the hippocampus by polyubiquitination after retrieval of contextual fear memory. Moreover, the infusion of proteasome inhibitor into the CA1 region immediately after retrieval prevented anisomycin-induced memory impairment, as well as the extinction of fear memory. This suggests that ubiquitin- and proteasome-dependent protein degradation underlies destabilization processes after fear memory retrieval. It also provides strong evidence for the existence of reorganization processes whereby preexisting memory is disrupted by protein degradation, and updated memory is reconsolidated by protein synthesis.
Interval state observer based on a time-variant transformation for LPV systems and application to induction machines

For the state estimation of safety-critical systems, interval observers are an emerging alternative to classical state estimation methods due to their provision of guaranteed information on unmeasurable quantities. One possible application of interval observers are induction machines used as a traction drive whose common models belong to the class of linear parameter-varying (LPV) systems. To overcome the design conditions of existing interval observers for LPV systems, which are too strict for an application to the aforementioned system, we propose a new interval observer design based on a time-variant transformation. The effectiveness of the method is shown by experimental results of an induction machine.
The impact of psychological factors in recovery following surgery for hip fracture

Purpose. To increase awareness of psychological factors in recovery from hip fracture and to describe strategies that can be used to help patients in the process of recovery. Method and results. Psychological theory, case examples and clinical observation are used to propose three frameworks for understanding the psychological factors which can impede recovery. Indication of key strategies for assessment and intervention which can be used in rehabilitation services is provided. Conclusions. An understanding of the psychological factors which can impede recovery in hip fracture is important for all professionals involved in rehabilitation. Psychologists can provide consultation and support for staff working in physical rehabilitation and can work directly with cases where there is complexity. There is still relatively little known about this important area and further research is needed to provide a clear evidence base.
Finding future high-cost cases: comparing prior cost versus diagnosis-based methods.

OBJECTIVE To examine the value of two kinds of patient-level dat a (cost and diagnoses) for identifying a very small subgroup of a general population with high future costs that may be mitigated with medical management. DATA SOURCES The study used the MEDSTAT Market Scan (R) Research Database, consisting of inpatient and ambulatory health care encounter records for individuals covered by employee- sponsored benefit plans during 1997 and 1998. STUDY DESIGN Prior cost and a diagnostic cost group (DCG) risk model were each used with 1997 data to identify 0.5-percent-sized "top groups" of people most likely to be expensive in 1998. We compared the distributions of people, cost, and diseases commonly targeted for disease management for people in the two top groups and, as a bench mark, in the full population. PRINCIPAL FINDINGS the prior cost- and DCG-identified top groups overlapped by only 38 percent. Each top group consisted of people with high year-two costs and high rates of diabetes, heart failure, major lung disease, and depression. The DCG top group identified people who are both somewhat more expensive ($27,292 vs. $25,981) and more likely ( 49.4 percent vs. 43.8 percent ) th an the prior-cost top group to have at least one of the diseases commonly targeted for disease management. The overlap group average cost was $46,219. CONCLUSIONS Diagnosis-based risk models are at least as powerful as prior cost for identifying people who will be expensive. Combined cost and diagnostic data are even more powerful and more operation ally useful, especially because the diagnostic information identifies the medical problems that may be managed to achieve better out comes and lower costs.
Experimental varicocele induces testicular germ cell apoptosis in the rat.

PURPOSE We evaluated the impact of experimentally created varicocele on ipsilateral and contralateral testicular germ cells in the rat. MATERIALS AND METHODS Experimental left varicocele was created by partial ligation of the left renal vein in 17 adult male Sprague-Dawley rats. An additional 5 rats that underwent laparotomy and renal vein handling without ligation served as sham surgical controls. Five rats that underwent no surgical or other intervention served as a control group. Rats were sacrificed 7 (5), 14 (5) or 28 (7) days following varicocele creation. Germ cell apoptosis was quantified using a TUNEL assay. The results of this assay are expressed as the number of apoptotic germ cell nuclei per seminiferous tubular cross section. The presence of apoptosis was confirmed by cellular ultrastucture evaluation using transmission electron microscopy. RESULTS Control and sham animals were found to have a mean of 0.05 and 0.15 apoptotic germ cells per seminiferous tubular cross section, respectively. Rats sacrificed 7, 14 and 28 days after varicocele creation were found to have 0.15, 0.23 and 0.27 apoptotic germ cells per tubule in the ipsilateral testis, and 0.14, 0.16 and 0.17 apoptotic germ cells per tubule in the contralateral testis, respectively. Compared with control animals a statistically significant increase in the number of apoptotic germ cells per tubular cross section was noted 14 days following varicocele creation in the ipsilateral testis (p <0.05). CONCLUSIONS The creation of experimental varicocele generated an increase in germ cell apoptosis in the ipsilateral testis at 14 days compared with control animals.
CORONARY VASOCONSTRICTION BY LOCALLY ADMINISTERED ACETYLCHOLINE, CARBACHOL AND BETHANECHOL IN ISOLATED, DONOR‐PERFUSED, RAT HEARTS

1 Experiments were carried out on rat isolated heart preparations in which the coronary vasculature was perfused through the aorta at a constant flow rate with arterial blood from donor animals. Single doses of drugs were injected into the aortic cannula. 2 Small doses of acetylcholine, carbachol or bethanechol decreased perfusion pressure (PP) without markedly affecting left ventricular pressure (LVP) and heart rate (HR); larger doses of these drugs increased PP (vasoconstriction), and decreased LVP and HR in a dose‐dependent manner. 3 Acetylcholine, carbachol and bethanechol had almost no effects when perfused through the aorta in such a way as to exclude the coronary vessels. 4 Coronary vasoconstriction in response to acetylcholine, carbachol and bethanechol was not significantly affected by reserpine pretreatment, phentolamine or hexamethonium, but was antagonized by small doses of atropine. 5 From these results it is concluded that in the coronary vasculature of the rat, the receptors involved in the vasoconstrictor actions of acetylcholine, carbachol and bethanechol are muscarinic.
Evaluation of a New Automated, Standardized Generic Nucleic Acid Extraction Method (Total Nucleic Acid Isolation Kit) Used in Combination with Cytomegalovirus DNA Quantification by COBAS AMPLICOR CMV MONITOR

ABSTRACT The new generic Total Nucleic Acid Isolation kit improved the detection limit of a cytomegalovirus (CMV) PCR from 400 to 200 copies/ml. Sensitivity and specificity in 30 CMV-positive and 100 negative samples were 100%. Analytical performance was excellent. The kit provides a reliable, standardized, and time-saving tool for DNA extraction.
KLF2 Suppresses TGF-&bgr; Signaling in Endothelium Through Induction of Smad7 and Inhibition of AP-1

Objective—The flow-responsive Kruppel-like factor 2 (KLF2) is crucial for maintaining endothelial cell quiescence. Here, we describe its detailed effects on transforming growth factor-&bgr; (TGF-&bgr;) signaling, which normally has proatherogenic effects on endothelium. Methods and Results—In-depth analysis of genome-wide expression data shows that prolonged lentiviral-mediated overexpression of KLF2 in human umbilical vein endothelial cells (HUVECs) diminishes the expression of a large panel of established TGF-&bgr;–inducible genes. Both baseline and TGF-&bgr;–induced expression levels of plasminogen activator inhibitor 1 (PAI-1) and thrombospondin-1 are greatly diminished by KLF2. Using a combination of ectopic expression, small interfering RNA–mediated knockdown, and promoter activity assays, we show that KLF2 partly inhibits the phosphorylation and subsequent nuclear accumulation of Smad2, thereby suppressing the TGF-&bgr;–induced Smad4-mediated transcriptional activity. This is achieved through TGF-&bgr;–independent induction of inhibitory Smad7. Additionally, a full inhibition of TGF-&bgr; signaling is functionally achieved through a simultaneous suppression of activator protein 1 (AP-1), which is an essential cofactor for TGF-&bgr;–dependent transcription of many genes. Conclusions—The concerted mechanism by which KLF2 inhibits TGF-&bgr; signaling through induction of inhibitory Smad7 and attenuation of AP-1 activity provides a novel mechanism by which KLF2 contributes to sustaining a quiescent, atheroprotective status of vascular endothelium.
Entropic Analysis and Synthesis of Biosignal Complexity

Analysis of complexity of biological time-series data is investigated to gain knowledge about the biosignal predictability. Using modern biological data such as mass spectral, this complexity information can be utilized to identify novel biomarkers for drug discovery, early disease detection and therapeutic treatment. To enhance the complexity analysis, a probabilistic fusion scheme, which is an alternative to the assumption of the independence of probabilistic models, is applied to synthesize the information given by different entropy methods.
Stress, Insulin Antagonist and Transient Diabetes Mellitus in the Rat

Summary The diabetogenic activity of growth hormone (GH) was studied through the production of an insulin antagonist in the plasma of normal rat. This antagonist, called alpha2-inhibitor, has an inhibitory activity on the glucose uptake by isolated testis, epididymal fat and hemidiaphragm of normal rat, is GH-dependent and has been identified with a fraction of plasma alpha2 -glycoproteins. The functional dependence of alpha2-inhibitor from GH was studied in two conditions: a) post-stress hypersecre tion of GH; and, b) post-administration of rat GH, without stress. The results showed the production of the alpha2 -in hibitor in both conditions, 3 hours post-stress or GH ad ministration. Since the normal intact Sprague-Dawley male rat has no plasma alpharinhibitor, it is concluded that it was induced by the stress. In the 80% pancreatectomized rat, the systemic stress pro duced, together with the increment of plasma alphaz -inhi bitor, a transient state of diabetes mellitus that lasted 4 hours and attained the peak 2 hours post-stress.
A Quantitative Immunoassay Utilizing Escherichiacoli Cells Possessing Surface‐Expressed Single Chain Fv Molecules

A facile, quantitative immunoassay is described that utilizes Escherichia coli (E. coli) bacteria expressing single chain Fv (scFv) antibody fragments attached to the cell surface. A Scatchard analysis demonstrated that the antibodies on the surface of the cells retained full binding activity (Kd = 2.2 × 10−9 M) and that there are 60 000 scFv molecules per cell. The cells are used as the antibody reagent in the assay, and, following incubation with analyte, simple centrifugation is used to separate the antibody‐bound from unbound analyte. The immunoassay is rapid and accurate down to the nanomolar level. In addition, a variety of detection strategies can be used, and the immunoassay is not adversely affected by the presence of animal serum. A key advantage of the new immunoassay is that the antibody reagent can be inexpensively produced in a “ready to use” form by simply growing cultures of the bacteria.
Thermal image analysis for polygraph testing.

We have designed, developed, and tested a very promising thermal image analysis method for polygraph testing. The method achieved a correct classification rate of CCR= 84% on the test population to our avail. This method, once refined, can serve as an additional channel for increasing the reliability and accuracy of traditional polygraph examination. We extract subtle facial temperature fluctuation patterns through nonlinear heat transfer modeling. The modeling transforms raw thermal data to blood flow rate information. Then, we use the slope of the average periorbital blood flow rate as the feature of a binary classification scheme. The results come to support our previous laboratory findings about the importance of periorbital blood flow in anxious states.
Active Learning Techniques (ALT) in a Mathematics Workshop; Nigerian Primary School Teachers’ Assessment

Pemahaman konseptual harus ditekankan bagi setiap mahasiswa Pendidikan Matematika. Pemahaman konseptual adalah pemahaman konsep-konsep matematika, operasi dan relasi dalammatematika. Dalam struktur aljabar, mahasiswa dapat belajar tentang pentingnya peran timbal balik antara konsep matematika dan bahasa. Pemahaman konsep merupakan salah satu kecakapan atau kemahiran matematika yang diharapkan dapat tercapai dalam belajar matematika yaitu dengan menunjukkan pemahaman konsep matematika yang dipelajarinya, menjelaskan keterkaitan antar konsep dan mengaplikasikan konsep atau algoritma secara luwes, akurat, efisien, dan tepat dalam pemecahan masalah. Namun dalam kenyataannya, masih banyak mahasiswa yang belum belum menguasai konsep pada teori grup, dengan baik. Hal ini ditunjukkan dengan masih banyaknya nilai mahasiswa yang kurang memuaskan. Berdasarkan penelitan yang telah dilakukan oleh peneliti-peneliti lain sebelumnya diketahui bahwa pemahaman mahasiswa tentang konsep grup sangat dipengaruhi oleh kemampuan matematis mahasiswa.
Mediating the effects of work-life conflict between transformational leadership and health-care workers' job satisfaction and psychological wellbeing.

AIM To explore the mediating effects of work-life conflict between transformational leadership and job satisfaction and psychological wellbeing. BACKGROUND The importance of work-life balance for job satisfaction and wellbeing among health-care employees is well-recognized. Evidence shows that transformational leadership style is linked to psychological wellbeing. It is possible that transformational leadership is also associated with employees' perceptions of work-life conflict, thereby influencing their job satisfaction and wellbeing. METHODS A longitudinal design was used where staff working within Danish elderly care completed a questionnaire at baseline and 18-month follow-up (N=188). RESULTS Regression analyses showed that transformational leadership style was directly associated with perceptions of work-life conflict, job satisfaction and psychological wellbeing. Work-life conflict mediated between transformational leadership and wellbeing, but not job satisfaction. CONCLUSION The findings suggest transformational leadership style may improve perceptions of work-life balance and employee wellbeing. IMPLICATIONS FOR NURSING MANAGEMENT Managers should adopt transformational leadership styles to reduce work-life conflict and enhance the wellbeing of their staff.
[A retrospective survey in child sexual abuse among 565 university students].

OBJECTIVE To examine the child sexual abuse (CSA) experiences and its associations with self-reported mental health status and risky behaviors among university students. METHODS A retrospective survey was conducted in 565 undergraduate students, from a university in northeast China, by anonymous self-administered questionnaire in September 2003. Research subjects were asked on a series of retrospective questions about CSA, as well as questions on depression, self-esteem, symptoms of psychological disease and risky behaviours. RESULTS Prevalence of any unwanted sexual experience before the age of 16 years was 20.0% for females and 14.3% for males. 11.3% of females and 7.7% of males reported ever having had at least one type of physical contact abuse. The students with CSA were with more depression, lower health self-evaluation; more symptoms in somatization, hostility, obsessive and anxiety. More students reported to have experienced sexual intercourse, been drunk, and suicide ideation than unaffected students. CONCLUSION The results indicated that unwanted child sexual abuse was not uncommon, and associated with poor mental health. The findings highlighted the urgent need for sexual abuse prevention programs and mental health services for victims in China.