Miracle-dz/UniFAR-FTUs huggingface dataset:
Identification and characterization of the protein product of gene 67 in equine herpesvirus type 1 strain Ab 4

Equine herpesvirus type 1 (EHV-1) strain Ab4 gene 67 has no counterpart in any herpesvirus sequenced to date. To identify and characterize the product of EHV-1 gene 67, we have expressed the putative amino acids 11 to 260 encoded by gene 67 as a fl-galactosidase fusion protein in Escherichia co6. The expressed fusion protein has been used to generate an antiserum raised against the gene 67 product. Immunoblotting and immunoprecipitation experiments have revealed that the anti-67 serum specifically recognizes a polypeptide with an Mr of 36000 (the 36K polypeptide) in infected cell extracts. The gene 67 protein is regulated as an early polypeptide in EHV-1 strain Ab4 infected cells and post-translational modification experiments have revealed that the protein is phosphorylated, but not glycosylated. The gene 67 protein has been transiently expressed in BHK-21/C13 cells using plasmid pCMV67, which contains the putative gene 67 ORF under the control of the cytomegalovirus immediate early promoter. Immunoblotting experiments with anti-67 have shown that the 36K protein is expressed at high levels in transfected cells. From both immunofluorescence and cellular fractionation experiments it is concluded that the gene 67 protein is associated with intracellular membranes and produces novel ribbon or filament-like structures within the cytoplasm of infected cells. We have demonstrated that the gene 67 product is a component of the virion nucleocapsid/tegument.
The Use of Anglicisms in Various Thematic Fields : An Analysis Based on the Corpus de Referencia del Español Actual *

This piece of research presents an analysis of the use of anglicisms in the Spanish press at the beginning of the 21st century. Specifi cally, it concentrates on their distribution in texts belonging to diff erent thematic domains. Thus, the purpose of this study is to establish a ranking of specialised fi elds in terms of the frequency with which anglicisms are employed in them. In order to do so, the Corpus de Referencia del Español Actual (CREA), compiled by the Real Academia Española, is used as the source for texts, which supports the reliability and representativeness of the present work.
The relation between fabric construction, treatments and sewability

In this study, the effects of fabric construction and treatments on the sew ability of cotton/polyester woven fabric are investigated. Fabric mechanical tests are measured using FAST (Fabric Assurance by Simple Testing) system, for assessing aspects of the performance in garment manufacture and garment appearance after wear. The optimization construction are used to carry out treatments impart to improve pilling and antimicrobial activity. The effect of fabric construction and treatments on sewing needle penetration of untreated and treated fabric is measured for determine any damage which appears in garment. It was found that formability, bending rigidity and shear rigidity decrease with decrease the weft count, but extensibility increase consistently. Also, the construction of plain has count No.40/1 gave low force penetration. (F. Fathy Saied, Z. m.abdel-megeid and L.K. El Gabry. The relation between fabric construction,treatments and
Concurrent Learning Adaptive Finite-Time Control for Spacecraft With Inertia Parameter Identification Under External Disturbance

This article investigates the postcapture control problem for the combined spacecraft formed after a service spacecraft captures a noncooperative target by manipulators. Two concurrent learning adaptive finite-time controllers are developed to achieve trajectory tracking and inertia parameter identification simultaneously. As a very common uncertainty affecting the spacecraft motion, the external disturbance should be considered, but it is ignored in most studies identifying inertia parameters. In this article, the presented controllers are designed according to the specific knowledge of the external disturbance: one controller is designed based on the disturbance bound that is assumed to be known; the other identifies the disturbance parameters together with the inertia parameters, presupposing that the nonlinearities involved in the external disturbance are known. Both of the two controllers require no a priori knowledge of the mass and inertia matrix of the combined spacecraft and take the input saturation into account. Sufficient conditions to identify inertia parameters are also given with no need of persistent excitation. The convergence of the closed-loop system is proved within the Lyapunov framework. Numerical results show that the proposed controllers can track the desired position and attitude trajectories in finite time, and, at the same time, the inertia parameters converge to their real values.
Implementation of Fall Detection and Localized Caring System

We propose the fall detection and localized caring system to effectively detect the postures of a human and provide a service of remote connection with health care center. Especially, when elderly people fall down, they often need to be hospitalized. The system can inform the care center automatically through the wireless sensor network and send the rapid information of the incident for their family through the mobile phone. It also provides the location of incident for immediate rescue by dispatching medical staff from the center. The experimental results show that our system achieves the accurate rate of 99.9% for detecting a human fall and provides the care services effectively.
Title The CDI toxin of Yersinia kristensenii is a novel bacterial member of the RNase A superfamily Permalink

Contact-dependent growth inhibition (CDI) is an important mechanism of inter-bacterial competition found in many Gram-negative pathogens. CDI+ cells express cell-surface CdiA proteins that bind neighboring bacteria and deliver C-terminal toxin domains (CdiA-CT) to inhibit target-cell growth. CDI+ bacteria also produce CdiI immunity proteins, which specifically neutralize cognate CdiA-CT toxins to prevent self-inhibition. Here, we present the crystal structure of the CdiA-CT/CdiIYkris complex from Yersinia kristensenii ATCC 33638. CdiA-CTYkris adopts the same fold as angiogenin and other RNase A paralogs, but the toxin does not share sequence similarity with these nucleases and lacks the characteristic disulfide bonds of the superfamily. Consistent with the structural homology, CdiA-CTYkris has potent RNase activity in vitro and in vivo. Structure-guided mutagenesis reveals that His175, Arg186, Thr276 and Tyr278 contribute to CdiA-CTYkris activity, suggesting that these residues participate in substrate binding and/or catalysis. CdiIYkris binds directly over the putative active site and likely neutralizes toxicity by blocking access to RNA substrates. Significantly, CdiA-CTYkris is the first non-vertebrate protein found to possess the RNase A superfamily fold, and homologs of this toxin are associated with secretion systems in many Gram-negative and Gram-positive bacteria. These observations suggest that RNase Alike toxins are commonly deployed in inter-bacterial
On the Long-Run Equilibrium Relationship among Health Care Expenditures, Public Pension and Social Insurance Burden Rate in Japan

Despite a decrease in the number of working generations supporting Japan's social security system, the relationship between public pension benefits and health care expenditures since the inception of universal health insurance system has not been explored. We obtained one stable long-run equilibrium relationship among those three variables over the period from 1966 to 2002. We employed the forecast error variance decomposition to examine the determination of social insurance burden rate. It is found that health care shock was important for the long-run determination of social insurance burden rate. Because it appears that a free health service system for the elderly (health care shock) caused the increase in the doctor's consultation, we estimated the health care function to analyze price policy in the health care sector. We finally accepted the dynamic OLS model with lead lags as an aggregated health care function. The price elasticity of health care has declined in absolute value since the universal health insurance system started, and it has been around 0.6 since the early 1980s. The policy which eliminated health care fees for the elderly in the 1970s was a mistake since the elderly increased their health care expenditures. The out-of-pocket expenses for health care of the elderly should have been raised in the 1970s.
Exploring ‘Successful’ Outcomes of Entrepreneurship Education

During 2005–2006 entrepreneurship students in several UK universities completed a survey about their background and career intentions. This paper reports, eight years on, on a follow-up study with ten of these participants, with the aim of exploring the students' intentions and subsequent actions since graduating. Using a qualitative methodology, the authors examined whether those who were measured as likely to be entrepreneurial are entrepreneurs; and whether the participants consider that their entrepreneurship education experience was valuable. The study finds that career experiences and outcomes are highly idiosyncratic and do not seem to correspond closely to original intentions, regardless of original ambitions. The authors suggest that career destinations are complex in a dynamic graduate employment context, and that entrepreneurship education has a contribution to make for graduates, irrespective of whether or not they become entrepreneurs. The paper identifies a weakness in entrepreneurship education research in its over-reliance on agency-based approaches and its assumption that outcomes are measured in the binary terms of ‘entrepreneur’ or ‘not entrepreneur’. The authors recommend methodological development in the field to capture more appropriately the rich and nuanced relationship between entrepreneurship education and graduate careers. This should lead to a more robust understanding on which to base information for delivery and practice.
On the tolerance averaging of heat conduction for periodic hexagonal-type composites

The paper deals periodic composites which two-dimensional material structure is determined by the anisotropic conductivity matrix invariant with respect to the pair of translations such that the periodic cell determined by them coincide with the shapely hexagon. Moreover, it will be assumed that the material structure is invariant over the π/3-rotations with the centers of every hexagon as the origin of the rotation. The main aim of this paper is to prove that the tolerance model of such composite, obtained by the orthogonalization method, is isotropic.
Reality Construction of Gamers in Online Media (Case Study : Kompas.Com)

Gamers as a term for online game players initially had a negative stigma as a lazy and antisocial group. But along with the industrial revolution 4.0, many studies have shown changes in the stigma of gamers in the community. Changes in the pattern of thinking or the view of society towards gamers is not separated from social construction. Peter L. Berger and Thomas Luckmann view social reality as a dialectical process that passes externalization, objectivation and internalization. This research is to find out the reality construction of gamers in kompas.com online media. With the Pan & Kosicki framing method, the analysis unit of this study is 5 article text gamers news on kompas.com. The results showed kompas.com frame the reality of gamers in a positive stigma in the discourse of promising professional opportunities, opportunities for e-sports athletes, and the phenomenon of the opening of current study programs in universities.
Is arthritis associated with cardiovascular diseases in both sexes? An analysis of NHANES data

Background: Among arthritis patients, cardiovascular morbidity is increased, and sex disparities exist in cardiovascular diseases and arthritis. Thus, the hypothesis that the association between cardiovascular diseases and arthritis might vary according to sex seems plausible. Aim: To examine the relationship of arthritis with the most frequently diagnosed cardiovascular diseases, and to check if sex modifies this association. Methods: We analyzed data from a large representative sample of the U.S. population: The National Health and Nutrition Examination Survey (NHANES) 2005- 2006. Our cross-sectional analyses included 3621 participants aged between 20 and 69 years old. Self-reported diagnoses of arthritis (main independent variable) and cardiovascular diseases (dependent variable) were measured during face-to-face interviews, and different covariates were identified as potential confounders for the association examined. Analyses were stratified by sex. Results: In multivariate analyses, a significant positive association was found between arthritis and cardiovascular diseases (OR: 2.01; 95% CI: 1.38-2.94; p value=0.0003), but there was no effect modification by sex (men: OR: 1.95; 95% CI: 1.32-2.87 / women: OR: 2.38; 95% CI: 0.96-5.86) (p=0,729). Conclusions: In this large cross-sectional study, we observed a statistically significant association between self-reported diagnoses of arthritis and cardiovascular diseases in a cohort of non-institutionalized U.S. adults. The association persisted after adjustment for several confounders but was not modified by sex.
Pulsars Probe the Low-Frequency Gravitational Sky: Pulsar Timing Arrays Basics and Recent Results

Abstract Pulsar Timing Array experiments exploit the clock-like behaviour of an array of millisecond pulsars, with the goal of detecting low-frequency gravitational waves. Pulsar Timing Array experiments have been in operation over the last decade, led by groups in Europe, Australia, and North America. These experiments use the most sensitive radio telescopes in the world, extremely precise pulsar timing models and sophisticated detection algorithms to increase the sensitivity of Pulsar Timing Arrays. No detection of gravitational waves has been made to date with this technique, but Pulsar Timing Array upper limits already contributed to rule out some models of galaxy formation. Moreover, a new generation of radio telescopes, such as the Five hundred metre Aperture Spherical Telescope and, in particular, the Square Kilometre Array, will offer a significant improvement to the Pulsar Timing Array sensitivity. In this article, we review the basic concepts of Pulsar Timing Array experiments, and discuss the latest results from the established Pulsar Timing Array collaborations.
Introduction to A Research Agenda for Social Finance

Social ventures, tackling social as well as environmental problems with hybrid business models, often function as non-governmental actors that pursue a predominantly social or environmental mission through their economic activity (Bertl, 2016; Geobey, Westley and Weber, 2012; Nicholls, 2010a; Weber, 2014). Lehner (2013) remarks that traditional means of finance may be inadequate for starting and sustaining such ventures due to their inherent abnormal risk premiums (Zerbib, 2019). Impact investing is one aspect of the newly emerged social finance sector (Bertl, 2016; Brandstetter and Lehner, 2015; Lehner, Harrer and Quast, 2019) that addresses this inadequacy and has gained importance since the term was first coined by the Rockefeller Foundation in 2007 (Harji and Jackson, 2012, 2018). Wood, Thornley and Grace (2013) assume that institutional impact investors can act as agents who are able to catalyze further investments in social ventures by legitimizing the industry. According to Lehner, Harrer and Quast (2018), however, the social impact investment market still appears to be in its infancy, with institutions lacking an understanding of its new and innovative hybrid business models (Kroeger and Weber, 2014; Lehner and Weber, 2020) and the necessary dyadic focus on socially driven investees, intermediaries and investors from various backgrounds, leading to complex negotiations. The resulting ‘liability of newness’ is intensified by a lack of terminological clarity as well as by a shortage of track records of successful high-quality impact investment opportunities (Nicholls, 2018; O’Donohoe et al., 2010) and imposes various constraints concerning access to resources.
The Democratisation Myth

Open access (OA) in the Global North is considered to solve an accessibility problem in scholarly communication. But this accessibility is restricted to the consumption of knowledge. Epistemic injustices inhering in the scholarly communication of a global production of knowledge remain unchanged. This underscores that the commercial or big deal OA dominating Europe and North America have little revolutionary potential to democratise knowledge. Academia in the Global North, driven by politics of progressive neoliberalism, can even reinforce its hegemonic power by solidifying and legitimating contemporary hierarchies of scholarly communication through OA. In a critique of the notion of a democratisation of knowledge, I showcase manifestations of OA as either allowing consumption of existing discourse or as active participation of discourse in the making. The latter comes closer to being the basis for a democratisation of knowledge. I discuss this as I issue a threefold conceptualisation of epistemic injustices comprising of testimonial injustice, hermeneutical injustice, and epistemic objectification. As these injustices prevail, the notion of a democratisation of knowledge through OA is but another form of technological determinism that neglects the intricacies of culture and hegemony.
Permanent and Transitory Wage Inequality of British Men, 1975-2001: Year, Age and Cohort Effects

We examine the variance-covariance structure of log-wages over time and over the lifecycle of British men from 1975 to 2001, hereby controlling for cohort effects. Wage inequality has risen sharply during the 1980’s and early 1990’s and remained fairly constant in the second half of the 1990’s. We show that this increase is caused mainly by a strong increase in the transitory wage inequality and only to a lesser extent to an increase in the permanent wage inequality. The transitory component of wages is, however, highly persistent over time: serial correlation decreases from 0.88 over a one-year period to 0.65 over a ten-year period. The constant wage inequality in the second half of the 1990’s is attributed to a slight decrease in permanent wages inequality, a stabilization of the variance of the transitory wage shock, and the strong decrease in the transitory wage inequality for the cohorts entering employment since the end of the 1980’s. Ignoring age effects in transitory wage inequality and cohort effects, as is commonly done, leads to severely distorted inferences concerning the changes in permanent wage inequality.
Multiscale Metrology and Optimization of Ultra-Scaled

A simulation methodology for ultra-scaled InAs quantum well field effect transistors (QWFETs) is presented and used to provide design guidelines and a path to improve device performance. A multiscale modeling approach is adopted, where strain is computed in an atomistic valence-force-field method, an atomistic spds* tight-binding model is used to compute channel effective masses, and a 2-D real-space effective mass based ballistic quantum transport model is employed to simulate three terminal current-voltage characteristics including gate leakage. The simulation methodology is first benchmarked against experimental I-V data obtained from devices with gate lengths ranging from 30 to 50 nm. A good quantitative match is obtained. The calibrated simulation methodology is subsequently applied to optimize the design of a 20 nm gate length device. Two critical parameters have been identified to control the gate leakage magnitude of the QWFETs, (i) the geometry of the gate contact (curved or square) and (ii) the gate metal work function. In addition to pushing the threshold voltage towards an enhancement mode operation, a higher gate metal work function can help suppress the gate leakage and allow for much aggressive insulator scaling.
Community and International Nutrition The Nutrition Transition Is Underway in India 1 , 2 , 3

Nutrition research in India has previously focused on the serious problem of undernutrition related to nutrient deficit and high rates of infection. Recent data from the National Family Health Survey 1998/99 (NFHS 2), however, identified a significant proportion of Indian women as overweight, coexisting with high rates of malnutrition. This paper examines the emerging nutrition transition for women living in rural and urban communities of Andhra Pradesh, India. NFHS 2 provides nationally representative data on women’s weight and height. In this paper, we examine representative data from the state of Andhra Pradesh (n 5 4032 women). Logistic regression analyses are applied to the data to identify socioeconomic, regional and demographic determinants of overweight and thinness. The major nutrition problem facing women continues to be undernutrition, with 37% having a low body mass index [(BMI) , 18.5 kg/m]; 8% of these women are severely malnourished (BMI , 16 kg/m). However, 12% of the women can be classified as overweight (BMI . 25 kg/m) and 2% are obese (BMI . 30 kg/m). Furthermore, in the large cities of the state in which 4% of the sample live, 37% of women are overweight or obese, whereas in the rural areas in which 74% reside, 43% have a low BMI. Women from lower socioeconomic groups are also significantly more likely to have a low BMI. Findings from the logistic regression models reveal socioeconomic status to be a more important predictor of both overand underweight than location of residence. J. Nutr. 131: 2692–2700, 2001.
MULTIPLY REFLECTED VARIANCE ESTIMATORS FOR SIMULATION

In a previous article, we studied a then-new class of standardized time series (STS) estimators for the asymptotic variance parameter of a stationary simulation output process. Those estimators invoke the well-known reflection principle of Brownian motion on the suitably standardized original output process to compute several “reflected” realizations of the STS, each of which is based on a single reflection point. We then calculated varianceand mean-squared-error-optimal linear combinations of the estimators formed from the singly reflected realizations. The current paper repeats the exercise except that we now examine the efficacy of employing multiple reflection points on each reflected realization of the STS. This scheme provides additional flexibility that can be exploited to produce estimators that are superior to their singlereflection-point predecessors with respect to mean-squared error. We illustrate the enhanced performance of the multiply reflected estimators via exact calculations and Monte Carlo experiments.