Miracle-dz/UniFAR-FTUs huggingface dataset:
Acrylonitrile-Styrene-Acrylate Particles with Different Microstructure for Improving the Toughness of Poly(styrene-co-acrylonitrile) Resin

Herein, acrylonitrile-styrene-acrylate copolymer (ASA) particles with different microstructure were synthesized by emulsion polymerization and then used for toughening poly(styrene-co-acrylonitrile) (SAN) resin. The structure of ASA particles was confirmed by FTIR. TEM results demonstrated that the particles with different morphologies of multilobe shape, complete core-shell and dumbbell shape were obtained depending on the cross-linker amount. It was found that the toughening efficiency reached the highest when the ASA particles had complete core-shell structure and the shell composition was close to that of the SAN matrix. It was ascribed to the fact that the complete shell layer and similar shell composition provided sufficient interfacial adhesion and transferred stress to induce larger matrix deformation, so that the notched impact strength increased accordingly. Moreover, the notched impact strength of SAN/ASA blend was improved without significantly sacrificing tensile strength when adding 30 wt% ASA particles with the size of around 400 nm. SEM results of the impact-fractured surfaces revealed that irregular fluctuation and numerous microvoids occurred. It was deduced that the toughening mechanism was attributed to the crazings and cavitation of particles. Therefore, this study paved a way of toughening the resin by adjusting the microstructure of the particles including morphology, composition, and size.
Research Progress on Association between Early-Life Exposure to Phthalates and Childhood Asthma

Phthalates (Phthalic acid esters, PAEs) as a common industrial products, a growing body of scientific evidences indicate that exposure to PAEs in early life has a potential harmful effect on the growth and development of organisms in later life, among these hazards, exposure to PAEs widely may increase the risk of asthma in children, which has attracted more and more attention. This article introduced the reasons and effects of PAEs exposure in early life, the relationships between early-life PAEs exposure and childhood asthma from the perspectives of epidemiological and animal studies and the underlying mechanisms of action.
ANTIPSORIASIS, ANTIOXIDANT, AND ANTIMICROBIAL ACTIVITIES OF AERIAL PARTS OF EUPHORBIA HIRTA

Objectives: The aim of the study was curing antipsoriasis through Euphorbia hirta. The antipsoriasis activity was done by the 3-[4,5-dimethylthiazol- 2-yl]-2,5 diphenyl tetrazolium bromide (MTT) assay method.Methods: Aerial parts were shade, dry for 2 days, make into coarse powder and soaked in methanol for 72 h. The supernatant liquid was filtered by Whatman filter paper and condensed in a hot plate at 50Â°C. Dark gummy mass obtained. The study identified the antioxidant, antimicrobial, and antipsoriasis activities of methanol extract of aerial parts of E. hirta.Results: The IC50 value of methanol extract of aerial parts was found to be 72.20 I¼g/mL, 97.88 I¼g/mL, 55.88 I¼g/mL, and 36.31 I¼g/mL by 1,1-diphenyl- 2-picrylhydrazyl radical scavenging assay, superoxide radical scavenging assay, phosphomolybdenum reduction assay, and ferric (Fe3+) reducing power assay. The antipsoriasis activity was done by the MTT assay method. The maximum cell death was 88.37% observed at 0.781 I¼g/mL concentration and IC50 was 12.20 I¼g/mL concentrated.Conclusion: The results of the present investigation reveal the antipsoriasis activity of the extracts of E. hirta against bacteria and viruses, the psoriasis causing organisms. The methanol extract of E. hirta shows antioxidant, antimicrobial, and antipsoriasis activity and can be used to formulate a potential therapeutic agent for psoriasis.
The Challenging Aspects of Digital Learning Objects Usage in a Primary School During the Pandemics

The COVID-19 pandemic situation forced to look for other ways to provide continuous education around the world, which highlighted the importance and necessity of online education platforms and digital learning object (DLO) while going through this shift (Zhou et al., 2020; Viner et al., 2020; Wang et al., 2020). Teachers, in primary schools as well, had to reorganize completely their curriculum and assignments to adapt them to the virtual environment. This paper, based on the experiences of primary school teachers, aims to reveal the challenges faced by the teachers when within two weeks all Lithuanian schools and universities had to switch to remote education from face-to-face education and when the adoption of DLOs moved from optional to compulsory ‘mode’ as learning process became remote. The research problem is analyzed primarily by revealing the theoretical aspects of the research, i.e., the concept of the DLO, the specifics of the adoption of DLOs in primary education and the challenges considered through the types of barriers. The findings indicate that teachers experienced challenges of practical training, issues in pupils’ assessment due to the lack of participation in the process of assignment completion, time constrain, different computer systems used, issues of online security, internet access and support. The study also identified the challenges of practical origin, namely, difficulties in keeping pupils’ concentration and attention throughout the lesson, lower level of teacher’s control during lessons as well as differences in pupils’ technical skills to use computers. Received: 2 August 2021 / Accepted: 20 August 2021 / Published: 5 September 2021
Repetitive Transcranial Magnetic Stimulation Improves Neuropathy andOxidative Stress Levels inRats with Experimental Cerebral Infarction through the Nrf2 Signaling Pathway

Department of Neurology, Hainan General Hospital, Hainan Affiliated Hospital of Hainan Medical University, Haikou, Hainan 570311, China Department of Urology, Hainan General Hospital, Hainan Affiliated Hospital of Hainan Medical University, Haikou, Hainan 570311, China Department of Emergency, Nanfang Hospital, Southern Medical University, Guangzhou, Guangdong 510515, China (e National Clinical Research Center for Mental Disorders & Beijing Key Laboratory of Mental Disorders, Beijing Anding Hospital, Capital Medical University, Beijing 100088, China Advanced Innovation Center for Human Brain Protection, Capital Medical University, Beijing 100088, China
Missile Longitudinal Dynamics Control Design Using Pole Placement and LQR Methods

In high-maneuvering missile systems, with severe restrictions on actuator energy requirements, it is desirable to achieve the required performance with least actuation effort. Linear Quadratic Regulator (LQR) has been in literature for long and has proven it’s mettle as an optimal controller in many benign aerospace applications and industrial applications where the response times of the plant, in most cases, are seen to be greater than 10 seconds. It can be observed in the literature that LQR control methodology has not been explored enough in the tactical missile applications where requirement of very fast airframe response times are desired, typically of the order of milliseconds. In the present research, the applicability of LQR method for one such agile missile control has been critically explored. In the present research work, longitudinal dynamic model of an agile missile flying at high angle of attack regime has been established and an optimal LQR control solution has been proposed to bring out the required performance demanding least control actuator energy. A novel scheme has been presented to further optimise the control effort, which is essential in this class of missile systems with space and energy constraints, by iteratively computing optimal magnitude state weighing matrix Q and control cost matrix R. Pole placement design techniques, though extensively used in aerospace industry because of ease of implementation and proven results, do not address optimality of the system performance. Hence, a comparative study has been carried out to verify the results of LQR against pole placement technique based controller. The efficacy of LQR based controller over pole placement design techniques is successfully established with minimum control energy requirement in this paper. Futuristic high maneuvering, agile missile control design with severe space and energy constraints stand to benefit incorporating the controller design scheme proposed in this paper.
Correlates of sperm quality parameters and oxidative stress indices in diabetic rats exposed to cold stress: Role of Moringa oleifera leaf extract

Spermatogenesis is extremely sensitive to fluctuations in the environment, particularly temperature and hormones. Sperm dysfunction, a root cause of male infertility, is a commonly allied complication of diabetes mellitus. Our previous studies cogitate that cold stress (15°C) exacerbates the complications and the resultant oxidative stress plays a major role in testicular and epididymis dysfunction in diabetic rats. Despite the strong biologic prospect for this postulation, establishing a direct link between free radicals and specific disease is an in-dire need, and in this context, this study focuses on investigating the sperm quality parameters and their relationship to testicular oxidative stress indices of cold stress diabetes in Wistar rats. The results indicate a cumulative impact by diminishing sperm parameters, viz. sperm density, viability, motility, mortality, and acrosome intactness in cold-stressed diabetic rats. The findings also reveal a strong positive Pearson’s correlation between the sperm quality parameters and testicular lipid peroxidation, which reflects the influence of oxidative stress on sperm dysfunction. Together with duel stressor effects, the efficacy of Moringa oleifera leaf ethanolic (MOLE) extract is appended to assess its therapeutic role. The apparent effectiveness of MOLE therapy at 250 and 500 mg/kg bw for 60 days aided in suppressing oxidative stress and improved semen quality demonstrating the causative nature of these associations; hence, Moringa usage is recommended as a therapeutic agent for male reproductive dysfunctions in population residing in colder climates.
Parallel Structure of Feedback Linearization and Sliding Mode Controllers to Track the Desired Velocity Profile in High-Speed Trains

High-speed railway vehicles operate much faster than traditional railway vehicles. After a four-axle high-speed railcar is modeled, an analytical solution is employed in this paper to solve dynamic equations. According to this analytical solution, the coupling of four-axle high-speed railcar equations depends strictly on the adhesion coefficient. A novel parallel control strategy is then formulated to prevent wheels from slipping and track the desired velocity profile. The proposed control strategy includes feedback linearization and sliding mode controllers to achieve the desired performance. Finally, the simulation results indicated the effectiveness of the proposed control system in the high-speed railcar such that the tracking error is less than 12%.
HBB gene cluster haplotype diversity in sickle cell anemia patients of Chhattisgarh, India

Sickle cell anemia (SCA) is one of the hereditary hemoglobin disorders in Indian populations. An exceptionally high prevalence of SCA is observed in the populations of Chhattisgarh. Restriction fragment length polymorphism (RFLP) haplotypes of the beta globin (HBB) gene cluster are important as population data, anthropological purpose for tracing migration of SCA allele and predicting the severity of SCA disease. The purpose of this study was to elucidate the HBB haplotypes and their correlation with clinical and hematological profile of SCA patients of Chhattisgarh population. The HBB gene cluster haplotypes were determined in 190 SCA patients by the polymerase chain reaction-restriction fragment length polymorphism method. Medical records of patients were reviewed to obtain pertinent clinical features, hemoglobin fractions, and other biochemical variables. Among the analyzed patients, 74% had Arab-Indian (AI) haplotype, followed by 21% atypical haplotypes. Senegal, Benin, and Cameroon types of HBB haplotypes represented 3%, 1%, and 1% of the patients, respectively. Comparison of various biochemical and hematological variables and clinical complications among various haplotypes did not reveal significant differences. The high frequency of atypical haplotypes observed may have been generated by single and double crossing-over between AI haplotype and normal HBB haplotype. Considering the Indian population’s genetic structure and diversity, the results of our study should be considered as introductory, and our study can serve as a possible tool for additional studies of SCA in India.
SAR_A_334851 81..88

1Department of Sociology, University of California, Riverside, CA, USA; 2Department of Sociology and Anthropology, Middle Tennessee State University, Murfreesboro, TN, USA Purpose: Unlike previous research, we evaluate disability within expanded employment status factors and stratify gender, race and ethnicity in alcohol-related liver disease (ALD) mortality in a large sample individual level longitudinal study. Materials and Methods: The National Longitudinal Mortality Study (NLMS) was used covering the period 1990–2011. Statistical analysis involved the use of proportional hazards regression on a sample of almost 1.4 million people aged 18 and older, of whom 2638 died of ALD by the end of the follow-up period. Results: With expanded employment status factors, disability (HR=3.76 [95%] CI 3.22, 4.39), unemployment (HR=1.90, CI 1.56, 2.31), and those not otherwise in the labor force (HR=2.31, CI 2.08, 2.56) were strongly related to ALD mortality compared to the employed. When stratified, gender, race, and ethnicity were not important modifiers in the relationships between disability, unemployment, those not in the labor force and subsequent ALD mortality. Consistent with other studies, males, minority status, living in a highly urban area, renting as opposed to owning a home, lower educational attainment, marital statuses other than marriage, low income, and age were related to ALD mortality. Conclusion: In addition to unemployment which has been previously studied in a large longitudinal sample, disabled people who were unable to work and those not looking for work had a higher risk of ALD mortality. Alcohol consumption, abuse and morbidity in these populations are of considerable clinical concern.
Efficient Data Mining Techniques for Heart Disease Prediction and Comparative Analysis of Classification Algorithms

Data mining techniques are used to extract interesting patterns and discover meaningful knowledge from huge amount of data. There has been increasing in usage of data mining techniques on medical data for determining useful trends and patterns that are used in analysis and decision making. About eighty percent of human deaths occurred in low and middle-income countries due to heart diseases. The healthcare industry generates large amount of heart disease data which are not organized. These data make the prediction process more complicated and voluminous. Data mining provides the techniques for fast and accurate transformation of data into useful information for heart diseases prediction. The main objectives of this research is to predict heart diseases more accurately using Naïve Bayes, J48 Decision Tree, Neural Network, Random Forest classification algorithms and compare the performance of classifiers. The research uses raw dataset for performance analysis and the analysis is based on Weka Tool. This research also shows best technique from them which is Random Forest on the basis of accuracy and execution time.
Time-kill kinetics and antibacterial activity of root extract of Adenodolichos paniculatus (Hua) Hutch & Dalz (Fabaceae)

Medicinal plants have been used in treatment of illness from time immemorial. Adenodolichos paniculatus is a medicinal plant used for traditional remedy of sore throat infections. This study therefore, evaluated the antibacterial activities of the root extracts and time-kill kinetics of the most potent extract. Five extracts, obtained by maceration using n-hexane, chloroform, ethyl acetate, methanol and water sequentially were evaluated for antibacterial activities and time-kill kinetics against Streptococcus pyogenes, Staphylococcus aureus, Pseudomonas aeruginosa and Escherichia coli. Chloroform root extract at 100 mg/ml was active against Streptococcus pyogenes, Staphylococcus aureus and Pseudomonas aeruginosa with zones of inhibition 25.00, 21.00 and 14.75 mm respectively but not against Escherichia coli. Minimum inhibitory concentrations were 1.56, 6.25 and 25.00 mg/ml respectively and the minimum bactericidal concentrations were 3.12, 12.50 and 50.00 mg/ml. Complete elimination of S. pyogenes, S. aureus and P. aeruginosa was achieved at concentrations 1.56 mg/ml, 6.25 mg/ml and 25.00 mg/ml within 300, 720 and 960 minutes exposure respectively and at concentrations 3.12 mg/ml, 25.00 mg/ml and 50.00 mg/ml within 180, 300 and 720 minutes exposure respectively. Chloroform root extract has the potential to be used as antibacterial agent and was better than the other solvent extract two-fold. Keywords: Adenodolichos paniculatus; Antibacterial activity; Time-kill kinetics; Percentage reduction, Log reduction
Managing Reputation, Sustainability, and Self-Interest: The Case of CEO Remuneration in the United States and the Importance of Being Earnest

Executive compensation has long been a lightening-rod of interest in the popular press and frequently makes the headlines. It seems that everyone has an opinion on the subject, with most demanding an end to inflated compensation packages. Depending on whether you are a member of the C-suite or not will likely skew your opinion on the matter. Given that the CEO is the most visible manifestation of the company to the outside world it is common to fixate on the way in which they are being compensated. However, after all of the research that has been conducted, we are still not sure about what factors determine a business executives’ pay. The present study seeks to add to the extant literature on the subject of CEO compensation by introducing a couple of promising new variables: corporate reputation and sustainability. It is argued that since the CEO is the face of the organization that he/she will be compensated based on how well they manage the firm’s reputation overall and its “environmental footprint” in particular.
Effect of the Interaction between Depression and Sleep Disorders on the Stroke Occurrence: An Analysis Based on National Health and Nutritional Examination Survey

Objective. To investigate the effect of the interaction between depression and sleep disorders on the stroke occurrence based on the data from the National Health and Nutritional Examination Survey (NHANES). Methods. Seven cycles of 2-year NHANES data (2005-2018) were analyzed in this study. Univariate analysis was first performed between the stroke and nonstroke patients, and then, multivariate logistic regression models were conducted to analyze the association of depression, sleep disorders, and their interactions with stroke occurrence. Results. A total of 30473 eligible participants were included in this study, including 1138 (3.73%) with stroke and 29335 (96.27%) with nonstroke. Except sex, the differences were all significant between the stroke and nonstroke patients in baseline information (all P < 0.001). Depression (odds ratio (OR): 2.494, 95% confidence interval (CI): 2.098-2.964), depression severity (moderate, OR: 2.013, 95% CI: 1.612-2.514; moderately severe, OR: 2.598, 95% CI: 1.930-3.496; severe, OR: 5.588, 95% CI: 3.883-8.043), and sleep disorders (OR: 1.677, 95% CI: 1.472-1.910) were presented to be associated with an increased risk of stroke after correcting all the confounders. The logistic regression analysis showed that there was a synergic, additive interaction between depression and sleep disorders on the stroke occurrence, and the proportion of stroke patients caused by this interaction accounted for 27.1% of all the stroke patients. Conclusion. Depression, depression severity, and sleep disorders are all independently associated with a high risk of stroke. The interaction between depression and sleep disorders can synergistically increase the stroke occurrence.
Donor or Acceptor? How Selection of the Rylene Imide End Cap Impacts the Polarity of π-Conjugated Molecules for Organic Electronics

Three molecular semiconductors are compared and evaluated in organic field-effect transistors and organic solar cells. The molecules are constructed from the dyes diketopyrrolopyrrole (DPP), perylene diimide (PDI), and N-(alkyl)benzothioxanthene-3,4-dicarboximide (BTXI). The compound PDI–DPP–PDI (1) has previously been reported and used as a nonfullerene acceptor. The compounds PDI–DPP–BTXI (2) and BTXI–DPP–BTXI (3) were synthesized using direct (hetero)arylation methods and fully identified using NMR spectroscopy and mass spectrometry. All three compounds were characterized using UV–visible spectroscopy, cyclic voltammetry, and density functional theory calculations. Increasing the BTXI content results in a progressive destabilization of the electronic energy levels. For all compounds, no significant changes in the optical absorption spectra are observed when compared to a combination of the constituent optical absorption spectra. Compound 1 exhibits electron transport characteristics and functions as an.
Ab Initio Calculations of the Redox Potentials of Additives for Lithium-Ion Batteries and Their Prediction through Machine Learning

Ab initio molecular orbital calculations were carried out to examine the redox potentials of 149 electrolyte additives for lithium-ion batteries. These potentials were employed to construct regression models using a machine learning approach. We chose simple descriptors based on the chemical structure of the additive molecules. The descriptors predicted the redox potentials well, in particular, the oxidation potentials. We found that the redox potentials can be explained by a small number of features, which improve the interpretability of the results and seem to be related to the amplitude of the eigenstate of the frontier orbitals.
Validity of the Scoring System for Traumatic Liver Injury: A Generalized Estimating Equation Analysis

http://www.jtraumainj. org eISSN 2287-1683 pISSN 1738-8767 Copyright © 2021 The Korean Society of Traumatology This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted noncommercial use, distribution, and reproduction in any medium, provided the original work is properly cited. Validity of the Scoring System for Traumatic liver Injury: a Generalized Estimating Equation analysis