Miracle-dz/UniFAR-FTUs huggingface dataset:
Insight into the structure of tetrameric flavoprotein WrbA involved in oxidative-stress response

Tato doktorska prace je zaměřena na strukturni charakterizaci specificke rodiny tetramernich flavoproteinů WrbA, jejichž uloha v živých organismech je do znacne miry neznama, ale zjistěna enzymaticka aktivita a podminky proteinove exprese indikuji tyto proteiny jako soucast obranných mechanismů proti oxidativnimu stresu. Nově zjistěna funkce dvouelektronove redukce chinonů je podobně jako u funkcně homolognich proteinů, chinonových oxidoreduktaz, spojovana s ochranou buňky proti tvorbě volných radikalů. V teto praci byly urceny krystalove struktury prototypniho proteinu WrbA z bakterie Escherichia coli, v ligandovane a neligandovane formě. Srovnavaci analýzy urcených struktur proteinu WrbA se strukturami přibuzných flavoproteinů umožnily identifikaci a interpretaci strukturnich vlastnosti, ktere definuji rodinu proteinů WrbA, a zaroveň vedly k objasněni strukturně-funkcnich vztahů s ostatnimi typy flavoproteinů.
Analysis of the Power Conversion Modes for Power-Efficient Energy Harvesting Interfaces

This paper analyzes the power conversion efficiency of conventional buck and buck-boost modes for power-efficient energy harvesting interfaces. In the state-of-the-art energy harvesting interfaces, they transfer harvested power mostly based on the conventional buck-boost mode. Since the power conversion efficiency is one of the most important performance factors for energy harvesting converters, this paper focuses on comparing the conventional power conversion modes based on formulas. In addition, the energy harvesting converter is designed in a 180 nm CMOS process and is simulated to prove that the power can be transferred properly with the analyzed power conversion modes. The converter operates in the discontinuous conduction mode with pulse-skipping modulation and employs the conventional open-circuit voltage method to track the maximum power point of each source. An adaptive on-time controller manages the inductor charging period, and a zero current detector, which is digitally operated, determines the optimum zero current point.
Comparison of main design concepts of auxiliary drives for DC catenary fed light traction vehicles: SiC JFET vs Si IGBT technology

ABSTRACT This paper presents a comparison of prospective design concepts of DC/DC isolated converters for auxiliary drives of DC catenary fed light traction vehicles. Auxiliary drives are mostly dedicated to generate standard power grid supplying various on-board equipment and to charge on-board batteries. The DC/DC isolated converter consists of full-bridge (FB) converter feeding a high frequency transformer (HFT) and SiC diode rectifier which produces a DC voltage bus line for 3-phase voltage-source inverter. The input FB converter is in our case designed using 1200 V devices in discrete (Si IGBTs) and module (SiC JFETs) version. The comparison deals both the hard switching and soft switching topologies of the converters. The investigated design concepts are experimentally tested up to the switching frequency of 200 kHz. The main aim of this paper is to compare efficiencies of SiC JFET and Si IGBT LLC full bridge converters operated under both continuous conduction mode (CCM) and discontinuous conduction mode (DCM). The introduced theoretical results and analyses are validated by the experiments made on developed prototype 8 kW, 400 V/600 V DC/DC isolated converter using SiC JFET and Si IGBTs
Tunable magnetic anisotropy in 2D magnets via molecular adsorption

2D ferromagnets show promising applications in low energy spintronics. However, the small magnetic anisotropy imposes a great limitation on the application scope. By using first principles modelling, we for the first-time report substantial tuning of magnetic anisotropy of a ferromagnetic CrI3 monolayer via a molecular adsorption strategy. We find that electron or hole doping has a significant impact on the magnetic anisotropy energy of 2D CrI3. Then we propose to realize charge carrier doping by the adsorption of electrophilic/nucleophilic molecules (TCNQ/TTF) on 2D CrI3. The largely controllable magnetic anisotropy is confirmed due to the interfacial electrostatic effects. Additionally, the out-of-plane magnetic anisotropy is also sensitive to the concentrations of organic molecules. The highest value reaches 1.17 meV Cr−1 in the hole-doped TCNQ-CrI3, while the lowest one is 0.20 meV Cr−1 in the electron-doped TTF-CrI3. Our work offers a feasible route to modulate the magnetic anisotropy of 2D magnets for practical magnetic applications.
Using Real-Time PCR to Investigate Some of Antibiotic Resistance Genes from Streptococcus agalactiae Isolates from ewe Mastitis cases in Nineveh province

هذه الدراسة ، من بين مجموعه 856 حالة من حالات التهاب الضرع في النعاج المرضعة ، أظهرت 34 عزلة فقط من المكورات العقدية اكالكشيا أنواعا مختلفة من المقاومة لثلاثة أنواع من المضادات الحيوية (البنسلين والإيثروميسين والتتراسيكلين). تم التعرف على عزلات المكورات العقدية اكالكشيا وفقا للطرق القياسية, بما في ذلك تقنية جديدة مقترحة باستخدام الاكار الكروموجيني المتخصص. حيث حددت المقاومة البكتيرية للمضادات الحيوية باستخدام مقايسة الصفيحة الميكروية (بطريقة التخفيف). أيضا، تم استخدام تقنية تقنية الوقت الحقيقي لتفاعل سلسلة البوليمر, حيث تم تحديد أن هناك ثلاثة مقاومة لمورثات الجينات (pbp2b وtetO و mefA). اظهرت النتائج نسبة التتراسيكلين (20.59%) مرتفعة من بين العزلات التي تحمل جين واحد، يليها نسبة البنسلين (17.65%), بينما أدنى نسبة كانت في الإريثروميسين (11.77%). مع ذلك, كان هناك العديد من العزلات التي تحمل جينين مقاومة للمضادات الحيوية يتمثل بـ البنسلين والاريثروميسين حيث تشكل (38.22%), في حين كانت النسبة المئوية للبنسلين والتتراسيكلين( 11.77%). في المقابل ، لم يتم الكشف عن أي جين شائع مع اثنين من المضادات الحيوية (الاريثروميسين والتتراسيكلين). من ناحية أخرى ، لم يتم العثور على اي نتائج بالنسبة لمشاركة مع ثلاثة أنواع من الجينات المقاومة للمضادات الحيوية معا ( pbp2bو tetO و mefA). كشفت هذه الدراسة أن عزلات المكورات العقدية اكالكشيا هي السبب الحقيقي وراء التهاب الضرع المتكرر في النعاج العراقية المرضعة وخصوصا في هذه الدراسة للبكتيريا التي تحمل جينات مقاومة للمضادات الحيوية المختلفة.
Psycho-Social Well-being in Female Students: the Role of Perceived Parental Autonomy Support and Warmth

1. Ph.D. Candidate in Educational Psychology, Department of Counseling and Educational Psychology, Faculty of Educational Sciences and Psychology, Ferdowsi University of Mashhad, Mashhad, Iran. 2. M.A. Student in Educational Psychology, Department of Counseling and Educational Psychology, Faculty of Educational Sciences and Psychology, Ferdowsi University of Mashhad, Mashhad, Iran. 3. Assistant Professor in Educational Psychology, Department of Personality and Educational psychology, Science and Research Branch, Islamic Azad University, Tehran, Iran. Article type: Research Abstract Purpose: According to self-determination theory well-being of individuals rests upon meeting the psychological need to autonomy, competence, and relatedness and the environment which provides the ground to meet these needs can facilitate psychological well-being of people. The goal of present research is to investigate the role of paternal and maternal autonomy support and warmth in psychological and social well-being of female students. Methodology: The design was correlational studies; 182 female freshmen students of Mashhad Payam-Noor University were selected using multistage random sampling and completed Perceptions of Parents Styles (POPS; Robbins, 1994), psychological well-being (Ryff, 1989) and social well-being (Keyes, 1998) questionnaires. Data analysis was done using correlation coefficients and stepwise regression in SPSS software. Findings: The findings showed that there was significant and positive relationship between paternal autonomy and social integration. Maternal warmth has positive relationships with self-acceptance, personal growth, social integration and social well-being. Paternal warmth has a positive significant relationship with self-acceptance, personal growth, psychological well-being, social integration, social contribution and social well-being. There was no significant relationship among maternal autonomy support with none of the research variables. Conclusion: It seems that warm and friendly behavior along with parents' affection toward children can have sustainable impacts on children's well-being. Article history: Received date: 2020/05/30 Review date: 2020/08/04 Accepted date: 2020/08/06
Factors affecting trapping success of red fox Vulpes vulpes, stone marten Martes foina and pine marten M. martes in France

Trapping records are often used to monitor long-term trends of small carnivore populations. However, many factors, not related to abundance, may affect capture rates. In this study, we examined whether trapper experience, trapping effort and trapping methods significantly affect capture rates of red fox Vulpes vulpes, stone marten Martes foina and pine marten M. martes. Data were collected from 58 trappers (35,774 trap-nights) in a 660-km2 study area during one trapping season. The main trapping methods used for foxes and martens with different types of traps were identified by multiple correspondence analyses on 424 trap sites. Generalised linear modelling showed that trapping methods, the length of time traps were set in the same place, trapper experience and the presence of captures in neighbouring trap sites significantly affect capture rates of foxes and martens. Given the high variability of capture rates among different combinations of these factors (0–3.4 captures/100 trap-nights for fox and 0.6–7.8 captures/100 trap-nights for martens), a separate trapping index should be calculated to detect trends in small carnivore populations.
A Survey of Resource Allocation Techniques for Cellular Network’s Operation in the Unlicensed Band

With an ever increasing demand for data, better and efficient spectrum operation has become crucial in cellular networks. In this paper, we present a detailed survey of various resource allocation schemes that have been considered for the cellular network’s operation in the unlicensed spectrum. The key channel access mechanisms for cellular network’s operation in the unlicensed bands are discussed. The various channel selection techniques are explored and their operation explained. The prime issue of fairness between cellular and Wi-Fi networks is discussed, along with suitable resource allocation techniques that help in achieving this fairness. We analyze the coverage, capacity, and impact of coordination in LTE-U systems. Furthermore, we study and discuss the impact and discussed the impact of various traffic type, environments, latency, handover, and scenarios on LTE-U’s performance. The new upcoming 5G New Radio and MulteFire is briefly described along with some of the critical aspects of LTE-U which require further research.
Mutation accumulation in selfing populations under fluctuating selection

Selfing species tend to be prone to extinction and this may be because selfing reduces the efficacy of selection acting to establish beneficial mutations and remove deleterious mutations from the population. Past theory shows that highly selfing populations can suffer from a continuous accumulation of deleterious mutations, a process analogous to Muller’s ratchet in asexual populations. However, current theory provides little insight into which types of genes are most likely to accumulate deleterious alleles and what environmental circumstances may accelerate genomic degradation. Here we investigate temporal changes in the environment that cause fluctuations in the strength of purifying selection acting on some genes. We simulate highly selfing populations with genomes containing a mixture of loci experiencing time constant selection and loci experiencing selection that fluctuates in strength over time (but not in direction). Even when both types of loci experience the same average strength of selection over time, loci under fluctuating selection contribute disproportionately more to deleterious mutation accumulation. Moreover, the presence of loci experiencing fluctuating selection in the genome increases the fixation rate of deleterious alleles at loci that are under constant selection; under most realistic scenarios this effect of linked selection can be attributed to a reduction in Ne. Fluctuating selection is particularly injurious to highly selfing populations when selective environments are strongly autocorrelated over time and when selection is concentrated into temporally rare environments in which selection is strong. From these results, we suggest that loci under fluctuating selection are likely to be important drivers of extinction in selfing species.
Numerical Simulations of Molten Breakup Behaviors of a de Laval-Type Nozzle, and the Effects of Atomization Parameters on Particle Size Distribution

In this work, an atomizer with a de Laval-type nozzle is designed and studied by commercial computational fluid dynamics (CFD) software, and the secondary breakup process during atomization is simulated by two-way coupling and the discrete particle model (DPM) using the Euler-Lagrange method. The simulation result demonstrates that the gas flow patterns greatly change with the introduction of liquid droplets, which clearly indicates that the mass loading effect is quite significant as a result of the gas-droplet interactions. An hourglass shape of the cloud of disintegrating molten metal particles is observed by using a stochastic tracking model. Finally, this simulation approach is used for the quantitative evaluation of the effects of altering the atomizing process conditions (gas-to-melt ratio, operating pressure P, and operating gas temperature T) and nozzle geometry (protrusion length h, half-taper angle α, and gas slit nozzle diameter D) on the particle size distribution of the powders produced.
Neuroprotective effect of Silibinin against middle cerebral artery occlusion induced focal cerebral ischemia and brain injury in Wistar rats

Silibinin (Silybin) as an active constituent derived from milk thistle (Silybum marianum) has been shown to have antioxidant and anti-apoptotic properties. In traditional system of medicine, Silybum marianum has been used for treating various kinds of ailments including liver disease and cancer; however, clinical studies are largely heterogeneous and contradictory. The present study was designed to investigate whether Silibinin protects neuronal injury against middle cerebral artery occlusion induced oxidative stress associated damages in focal cerebral ischemia in Wistar rats. Rats weighing 250 to 300 g were pretreated with Silibinin 100 mg/kg and 200 mg/kg body weight, suspended in 0.5% of gum acacia) once daily for seven days. On 8th day, they underwent for middle cerebral artery 2 h suture occlusion by nylon suture. After 120 min of middle cerebral artery occlusion (MCAO) and 22 h of reperfusion, behavioral tests were assessed in terms of neurological deficits. Animals were sacrificed and infarct volume in Triphenyltetrazolium chloride (TTC) stained brain sections was measured. Further, various oxidative biomarkers were estimated in brain homogenates of rats. Pretreatment with Silibinin at doses of 100 and 200 mg/kg significantly improved the neurobehavioural alterations and reduced the infarct volume whereas 200 mg/kg Silibinin significantly increases the Glutathione (GSH) level and the others parameters with respect to control values. These results clearly indicate the neuroprotective effect of Silibinin against middle cerebral artery occlusion associated with oxidative damage induced brain injury due to its antioxidant and anti-apoptotic property. Key words: Neuroprotective, MCAO, Silibinin, oxidative stress, infarct volume, cerebral ischemia.
Malarial infection alters wax ester composition of preen oil in songbirds: Results of an experimental study

ABSTRACT Increased exposure to parasites and other pathogens is one of the principal costs of group living, and animals have evolved diverse behavioral adaptations to detect and avoid parasitized conspecifics. In mammals, it is well established that parasitic infection can affect host body odor and that individuals use this chemical information in mate choice and other social contexts. In birds, despite intense interest in condition-dependent sexually selected displays as indicators of health status, chemical signaling of infection status remains largely unexplored. However, compounds in feather preen oil are increasingly recognized as candidate substances that may mediate chemical signaling in birds. We inoculated Song Sparrows (Melospiza melodia) with hemosporidian parasites (Plasmodium sp.) to determine whether parasitic infection alters the chemical composition of preen oil. We used gas chromatography with flame ionization detection (GC-FID) to separate and quantify the wax esters in preen oil and compared the chemical profiles of preen oil before inoculation to chemical profiles 13 days later (corresponding to peak infection intensity among the subset of birds that became acutely infected). Inoculation with Plasmodium sp. altered the wax ester profiles of preen oil, albeit with a modest effect size, regardless of whether individuals became acutely infected or resisted the infection. By contrast, wax ester profiles of preen oil were not significantly altered in individuals that received a sham inoculation with uninfected blood. Provided that birds can perceive these alterations in wax ester profiles of preen oil (e.g., after their degradation and release as volatiles), our findings suggest that chemical cues inherent in the wax esters may signal malarial infection status and/or exposure history.
Fusing Mobile Phone and Travel Survey Data to Model Urban Activity Dynamics

A key issue to understand urban system is to characterize the activity dynamics in a city—when, where, what, and how activities happen in a city. To better understand the urban activity dynamics, city-wide and multiday activity participation sequence data, namely, activity chain as well as suitable spatiotemporal models, are needed. The commonly used household travel survey data in activity analysis suffers from limited sample size and temporal coverage. The emergence of large-scale spatiotemporal data in urban areas, such as mobile phone data, provides a new opportunity to infer urban activities and the underlying dynamics. However, the challenge is the absence of labeled activity information in mobile phone data. Consequently, how to fuse the useful information in household survey data and mobile phone data to build city-wide, multiday, and all-time activity chains becomes an important research question. Moreover, the multidimension structure of the activity data (e.g., location, start time, duration, type) makes the extraction of spatiotemporal activity patterns another difficult problem. In this study, the authors first introduce an activity chain inference model based on tensor decomposition to infer the missing activity labels in large-scale and multiday activity data, and then develop a spatiotemporal event clustering model based on DBSCAN, called STE-DBSCAN, to identify the spatiotemporal activity patterns. The proposed approaches achieved good accuracy and produced patterns with a high level of interpretability.
Novel configuration of ultra‐wide band uni‐planar configuration of complementary split ring resonator composite right/left‐handed based band pass filter with sharp roll off and good stopband attenuation

In this paper, a compact novel simple design of ultra‐wide bandpass filter with high out of band attenuation is presented. The filter configuration is based on combining an ultra‐wide band composite right/left‐handed (CRLH) band pass filter (BPF) with simple uni‐planar configuration of complementary split ring resonator (UP‐CSRR). By integrating two UP‐CSRR cells, the ultra‐wideband CRLH filter roll‐off and wide stopband attenuation are enhanced. The filter has 3 dB cutoff frequencies at 3.1 GHz and 10.6 GHz with insertion loss equals 0.7 dB in average and minimum and maximum values of 0.48 dB and 1.05 dB, respectively over the filter passband. Within the passband. The transition band attenuation from 3 dB to 20 dB is achieved within the frequency band 1.9 GHz to 3.1 GHz (48%) at lower cutoff and the frequency band 10.6 GHz to 11.4 GHz (7%) at upper stopband. Moreover, the filter has a wide stopband attenuation >20 dB in frequencies 11 GHz to 13.6 GHz (21%) and ends with 3 dB cutoff frequency at 14.8 GHz. Furthermore, the designed filter size is very compact (23 × 12 mm2) whose length is only about 0.17 λg at 6.85 GHz. The filter performance is examined using circuit modeling, full‐wave simulations, and experimental measurements with good matching between all of them.
Two ascomycetes from different aquatic habitats

Two species of the genus Halosphaeria Linder were isolated from dead plant segments submerged in two lentic habitats. Halosphaeria cucullata (Kohlm.) was isolated from a stem segment of a reed submerged in Al-Soda Marsh Lake in Iraq where water salinity exceeds 1.6% as a salty environment. This species was distinguished by a small ascocarp (150-258 µm) and ascospore (8-10 × 20-28 µm) with a gelatinous appendage in the terminal end of the ascospore. Halosphaeria species was isolated from a segment of an unknown plant species submerged in Lake Sevan in Armenia. It was distinguished by a large ascocarp (200-300 µm) and ascospore (10-15 × 25-32 µm) with a sheath of hyaline gelatinous appendage surrounding the entire ascospore. The two isolates were described and illustrated as new records and kept in the Basrah herbarium under the number BSRA 9001 and BSRA 9002, respectively.
Coordinate Measuring Machine thread position measurement analysis

Measuring the true position of a cylinder with a Coordinate Measuring Machine became a simple fact for programmer developer, for this they have to choose between different strategies available on the CMM software to improve measurement accuracy. Everything is changing when we try to measure a true position threaded hole, during serial production this position will pass between some changes that will affect the profile of the thread and the beginning of the threaded hole. Although CMM cylinder strategies methods exist they are not efficiently developed for precise measurement of a thread position. This article will analyse the difference between current methods that are available on the market and will compare the results with an experimental new method, this new method is developed from the method available plus other tools available in the CMM software. The importance of this method is to increase thread position measurement precision during all production cycle time.
Hierarchical Bayesian model reveals the distributional shifts of Arctic marine mammals

Our aim involved developing a method to analyse spatiotemporal distributions of Arctic marine mammals (AMMs) using heterogeneous open source data, such as scientific papers and open repositories. Another aim was to quantitatively estimate the effects of environmental covariates on AMMs’ distributions and to analyse whether their distributions have shifted along with environmental changes.