Miracle-dz/UniFAR-FTUs huggingface dataset:
Understanding Pancreatic Secretion in Type 1 Diabetes

Type 1 Diabetes Mellitus (T1DM) is a chronic disease characterized by the immune-mediated destruction of β cells of pancreatic islets. Despite the increase of its incidence observed in last decades, it has not been fully elucidated the immunogenetic and environmental factors associated with the initiation and perpetuation of the pancreatic injury(1,2). The pathogenic process in T1DM begins with insulitis, which progresses and expands so as to be accompanied by cell necrosis. The rate of progression of the lesion is variable and may be related to age at onset of the disease, being faster in cases diagnosed in children (3). When approximately 80-90% of insulin-secreting cells have been destroyed, T1DM is clinically overt (4). T1DM patients may have some residual insulin secretion at diagnosis (5-8). Several studies indicate that the loss of functional capacity usually occurs within three to five years. Most patients with long duration of disease do not present clinical evidence of preservation of β cells (9-11). However, the conservation of some residual secretion, even insufficient to cure or prevent T1DM from using insulin, has been associated with a better prognosis regarding glycemic control, lower rates of hypoglycemia, diabetic retinopathy and nephropathy (12). One of the most frequently used method to assess β cell function in patients with T1DM is the determination of C-peptide (CP), a molecule secreted by β cells in equimolar concentrations with insulin and without significant liver metabolism (13-15). Taking into consideration the potential benefits of preserving a residual insulin secretion in patients with T1DM, experimental treatments have been proposed in order to maintain detectable levels of CP in these individuals. Developments in research aiming for the prevention and cure of T1DM, increased the need to elucidate the contributing factors for the maintenance of residual insulin secretion in patients affected by the disease. This is because individuals who still exhibit residual insulin secretion could be ideal candidates for new curative treatments. Furthermore, most studies of pancreatic function in T1DM have been performed in Caucasians and Asians. We do not know whether the results obtained so far can be extrapolated to other ethnic populations (16).
The Legal Response to Elder Abuse and Neglect

ABSTRACT The United States legal system, both civil and criminal, has been underutilised in dealing with elder abuse and neglect. Social service and health practitioners have been unfamiliar with the language and procedures in legal settings. Legal remedies have been obscure or inadequate to address the problems. When elder abuse and neglect were first “discovered” in the late 1970s, efforts focused on safeguarding the victim through civil justice remedies, i.e., guardianships, mandatory reporting laws, adult protective services. The criminal justice system also became involved in order to hold the alleged wrongdoer accountable. Specialised units have developed in police departments and prosecutor offices to deal with the criminal behavior. New laws are providing more flexibility for the legal system, both civil and criminal. A multidisciplinary approach to elder abuse and neglect is needed because abused or neglected elders are frequently involved with many agencies. Attention to the legal aspects of the issue are apparent in the Summit Conference held by the National Center on Elder Abuse in 2001 and the development of the Elder Justice Act which was introduced into the U.S. Senate in 2003.
Summary and Recommendations of the Academy's State of the Science Conference on Upper Limb Prosthetic Outcome Measures

The Academy's Ninth State of the Science Conference included a group of engineers, prosthetists, and therapists brought together to discuss upper limb prosthetic outcome measures. After a presentation of the evidence based review and discussions on the history of the field and the various perspectives from the various professions, the panel reviewed those outcome measures found to be recommended and those thought to be worth consideration by the Evidence Based Review and the Upper Limb Prosthetics Outcome Measures Group. Outcome measures with the potential to address certain research questions are identified. Throughout the various discussions of the SSC group, a list was kept of commonly identified issues, questions, and missing links. From this list, the panel identified seven key research priority questions. These priority questions and items included in the discussions are presented.
Depression and suicide in older people: Report of a workshop held at the ciba foundation, London, on November 11, 1994

Once a year, the British charity Research into Ageing, ‘founded to improve the life of older people through the initiation, funding and dissemination of research’, holds a workshop on an area of interest. Last year, the topic of depression and suicide was chosen and 22 participants were invited to read, listen to and discuss seven ‘position’ papers. Professor Dan Blazer presented reasons why some studies have found the prevalence of major depression among older adults to be lower than for other age groups. Some methods (a) discount depressive symptoms that fail to meet syndrome criteria derived from work with younger adults or that subjects attribute to physical illness, (b) miss depressed people admitted to hospital or to residential homes, and (c) employ styles of questioning not specifically designed for use in older people. Lowered survival due to suicide and physical illness may also contribute to apparent low prevalence, as can effects relevant to the unique historical experiences of different birth cohortssince 1988, suicide rates have increased by 25% in Americans now over 65 years of age. A recent study (Blazer et al., 1991) has shown an association between depressive symptoms and increased age to be reversed when factors such as low income, physical disability, cognitive impairment and poor social support are simultaneously controlled. It was agreed that the use of diagnostic systems developed for younger people, and the emphasis on studying categories rather than symptoms, has led to the neglect of some elderly people with
Titulus oppida capta leget : the Role of the Written Placards in the Roman Triumphal Procession

This paper examines the written placards that formed part of the Roman triumphal procession. The placards are commonly described as tabulae ansatae, but were, as is argued, rather tituli, that is placards used for short notes of contents. Based on a passage in Ovid, the article holds that the information advertised on the placards could be categorised as causae et res et nomina, causes for the display, objects paraded, and names of peoples and personifications. It is also argued that the placards in their very presence implied Roman conquest, in that they preceded «others» on parade, who were forced to walk behind and under labels that announced their identity and explained their misdeeds. Also, the tituli were written in Latin, hence implying a cultivated viewer who was able to read and acknowledge the display.
M2M ve IoT Platformları Üzerinde Prototip Uygulama Geliştirme

Teknolojinin ve internet alt yapisinin hizli gelisimi, gomulu cihazlari kullanarak insanlarin iletisim kurma seklini degistirmistir. Mevcut durumda fiziksel nesnelerin buyuk bir kisminin iletisim yetenegi bulunmamaktadir. Nesnelerin interneti (IoT: Internet of Things) yaklasimi ve Makinalar Arasi Iletisim (M2M: Machine to Machine) teknolojileri sayesinde nesnelere iletisim yetenegi kazandirilabilmektedir. Bu sayede nesnelerin uzaktan izlenmesi ve kontrolu gerceklestirilmektedir. M2M/IoT uygulamalarinin yonetilebilmesi icin M2M/IoT platformlari kullanilmaktadir. Bu calismada, oncelikle M2M/IoT teknolojisi aciklanmis M2M/IoT platformlari uzerinde prototip uygulama gelistirilmistir. Kullanilan platformlar mevcutta ticari olarak hizmet vermektedir. Bu platformlarin genel yapisi ve mimarisi, hangi alanlarda kullanildigi, platform uzerinde uygulamalarin nasil gelistirildigi incelenmistir. Uygulamaya bagli olarak M2M/IoT platformlarinin farkli islevsel ozelliklere sahip olduklari gorulmustur.
Virtual Oscillator based Hierarchical Control Strategy for Multi-mode Operation of Microgrids

One of the most important challenges in controlling a Microgrid is to enable a multi-mode operation with a smooth change from different modes. Recently, hierarchical control is considered as an effective approach to control and manage a Microgrid. This paper proposes a compatible hierarchical control strategy, leveraging the superior characteristics of Andronov-Hopf Oscillator, that enables both grid-connected and islanded operation, as well as seamless, reliable transition between operation modes. The proposed control strategy includes a PI-based Power Tracking Control loop, a Power Sharing Control loop using average consensus approach, a PR-based Synchronization Control, and a Fault Initiated Islanding Detection based on wideband, online impedance estimation. The results in MATLAB/Simulink are provided to validate the effectiveness of the proposed strategy.
Prevention and Treatment of Ovarian Hyperstimulation Syndrome

Ovarian hyperstimulation syndrome (OHSS) is a clinical symptom complex associated with ovarian enlargement resulting from exogenous gonadotropin therapy. In severe cases, a critical condition develops with massive ascites, marked ovarian enlargement, pleural effusion, electrolyte imbalance, hypovolemia with hypotension, oliguria, hemoconcentration, and thromboembolism (Madill JJ et al., 2008). Moderate to severe ovarian hyperstimulation syndrome (OHSS) has been calculated to occur in 0.2% to 2% of all ovarian stimulation cycles (Binder H et al., 2007).
News on the move: exogenous events and news coverage of the European Union

News coverage about the European Union (EU) has the potential to inform citizens about and to involve them in matters of European integration. Investigations of factors that explain variation in EU news coverage, however, are rare. This study explains weekly variation in the visibility of EU news in newspapers from seven EU member states for the period 1990 to 2006. It identifies exogenous factors that relate to the EU polity, its policies and national politics. The descriptive results show that EU news visibility has increased overall and that weekly variation is rather similar in the seven member states. News visibility is substantially influenced by infrequent polity-related events such as European Parliamentary (EP) elections or Council summits but also by EP sessions. Also policy-related and national events affect visibility. The findings are discussed in light of the democratic deficit of the EU and the potential consequences of visible EU news coverage.
A Variable Curvature Adaptive Trajectory Planning Method and Experiment for Robotic Belt Grinding of Blisk Surface

The blisk is a significant part of the new generation of an aero-engine, and its processing accuracy and surface integrity seriously affect the aerodynamic performance and service performance of the aero-engine. Robotic belt grinding (RBG) is an essential technology to guarantee the final accuracy of the blisk. To solve the problems of difficult trajectory planning, poor accuracy and low efficiency in the process of RBG with blisk surface, a variable curvature adaptive trajectory planning (VCATP) method is proposed. Firstly, the NURBS method is used to reconstruct the blisk surface. Then, considering the variable curvature characteristics of the blisk surface, an improved step-length(SL) and row-spacing(RS) calculation method is proposed according to the equal chord-height error method and constant scallop-height method, which can get all the grinding points(GPs) on the surface of blisk. Finally, the proposed VCATP method also can be verified by relevant experiments. And the experimental results show the average surface roughness Ra of blisk profile reaches 0.31$\mu$m, the machining efficiency is improved by 25%, and the profile accuracy is greatly improved.
Public policy implications of declining old-age mortality.

Recent years have witnessed dramatic improvements in the longevity of the US elderly population. This paper explores some policy implications of the dramatic longevity gains that have occurred and are likely to continue. It focuses on the potential burden through demand for medical care and other resources that the elderly are likely to create. The paper surveys some relevant evidence and presents some new calculations bearing on the effects of mortality improvements. While the available data permit only tentative conclusions it appears that reductions in morbidity associated with declining mortality have been counterbalanced by high morbidity rates among marginal survivors. As a consequence the health needs of elderly persons at given ages have not changed very much. The author argues that Poterba and Summerss conclusion that future medicare costs and costs of institutionalization can be predicted from current age-specific information consistent with the model and the empirical work but in practice it is too sweeping because it ignores the advent of the Medicare prospective payment system. Second Poterba and Summers argue that there is little basis for proposing a redefinition of the elderly because the health status of the typical 65-year-old 20 years from now is likely to be about the same as it is now but even if one accepts the argument that selection and medical progress have approximately offset each other in the past 20 years they may not do so in the next 20. Thirdly Poterba and Summers argue that it would be desirable to reorient medical progress toward policies that are less selective in their efforts on mortality but the author thinks that any attempt to reorient federal research and development policy may be ineffective in reorienting the total research and development effort.
The child with cerebral palsy in a developing country – diagnosis and beyond

Abstract Cerebral palsy (CP) is one of the leading causes of childhood disability worldwide, with the greatest burden found in the developing countries of the world. A longitudinal study was carried out on all consecutive new cases of CP who presented at the neuro-developmental clinic in Nigeria over a period of 6 months to evaluate the continuum of care available to children with CP following diagnosis. At the end of 1-year post-enrolment into the study, all cases were evaluated for survival, on-going rehabilitative care, functional improvement and reasons for default. Eighty-two children were enrolled into the study. Mean age was 25.3 ± (SD=25.5) months and the leading causes of CP were birth asphyxia (39.0%), bilirubin encephalopathy (24.4%) and post infectious brain damage (18.3%). By the end of 1 year, 61 (74.4%) had defaulted from follow up, 11 (13.4%) had died and only 21 (25.6%) were still receiving rehabilitative care. The major reasons for default were financial constraints, no improvement in condition and the hospital being too far from place of residence. Presence of severe functional impairment and absence of epilepsy were associated with an increased risk of default from medical care. In conclusion, CP remains a major cause of neurodisability in Nigeria. There is a high default rate with majority of children lacking ready access to medical care and education. There is an urgent need for improvement in medical services in the country and social support for children with CP and their families.
A comparative study of load sharing among back and leg muscles during squat and half-kneeling lifts

This paper presents the results of a comparative study of load sharing among back and leg muscles during squat and half-kneeling lifts. 19 young and healthy subjects with no history of low back pain or other musculoskeletal disorders participated in the study. Muscle activity was measured using electromyography (EMG) technique. Surface EMG electrodes were placed bilaterally at the erector spinae, quadriceps and hamstring muscles. Muscle activities were determined at different force levels representing 40, 60 and 80 percent of maximal voluntary contraction (MVC). The results showed increase in normalised mean RMS (root mean squared) values of EMG of for all the muscles with increasing force levels in both squat and half kneeling lifts. Contralateral and ipsilateral ratio parameters were used to determine the degree of load sharing among the muscles in both lifting postures. Statistical analysis of the mean RMS values and the contralateral and ipsilateral ratio parameters revealed no significant differences between squat and half kneeling lifts. The paper discusses the implications of the results for preventing injuries during manual handling and provides suggestions for future research.
Weight loss as an operant response

-The present study was designed to show that reinforcing a loss of' body weight relative to a previous measurement would affect an increase in the frequency of' trials during which a weight loss was observed. Volunteer females who reported problematic eating leading to overweight served as Ss. Baseline data were collected indicating each ~'s daily body weight and the median amount of daily body weight change across baseline. Ss were then reinforced for any daily weight loss which exceeded this median value. An extinction period followed during which no reinforcement followed a weight loss. The data failed to indicate either a reduction of body weight or an increased rate of trials during which a weight loss was observed. It was suspected that too large of a weight :ioss ~as required for reinforcement, preventing successful conditioning. A second experiment was conducted during which any daily weight loss, regardless of its magnitude, was reinforced. The results did not appreciably differ from those of the first
A Comparison Between Nonlinear Kalman Filters for Sensorless Induction Motor Drives

This paper presents a comparison between nonlinear Kalman filters for estimation in Sensorless induction motor drive applications. The extended Kalman filter (EKF), square-root unscented Kalman filter (SRUKF), and square root cubature Kalman filter (SRCKF) are considered. Each filter's performance is tested under dynamic and steady state conditions. Observability of each filter's state-space model is performed and analyzed. Sensorless direct torque control is utilized. Simulation and experimental results are presented to show superiority of both SRUKF and SRCKF when compared to EKF.
Immunohistochemical Study on Wound Healing of a Muscle Flap Transferred into the Oral Cavity of Rats

Immunohistochemical Study on Wound Healing of a Muscle Flap Transferred into the Oral Cavity of Rats. Oral Med Pathol 2001; 6: 29-36, ISSN 1342-0984. The immunohistochemical expressions of FGF2, FGFR1, FGFR2, and their possible participation in the apoptosis of myofibroblast were studied in the healing process of a muscle flap transferred into the oral cavity of rats. At 14 days postoperatively, abundant myofibroblasts were observed in the early-granulating muscle flap, and at 18 days postoperatively, they began to gradually disappear. The FGF2 immunopositive area, the number of FGFR2-positive fibroblasts and TUNEL-positive fibroblasts reached a maximum at 18 days postoperatively and gradually decreased thereafter, and there was a significant correlation of expression between the FGFR2-positive fibroblast and TUNEL-positive fibroblast. On the other hand, FGFR1-positive fibroblasts were observed from day 10 to 21 in the granulation tissue formation of the muscle flap. These findings suggest that FGFR1 may participate as a factor affecting tissue remodeling of muscle flap healing, and that FGFR2 may play a role in programmed cell death or apoptosis of myofibroblast.
Labour, mining, dispossession: on the performance of earth and the necropolitics of digital culture

ABSTRACT This paper places the territorial politics of digital culture within a material perspective, specifically, through studying forms of labour involved in the mining of rare earths and minerals to generate our digital infrastructures. Following Jussi Parikka’s lead in A Geology of Media (2015), I consider the deeper geological time of mineral formation, and analyse the intersection of labour and medianatures. Drawing attention to the exemplification of supply chain capitalism (Tsing), I look at the scales of violence of mining and the dispossession of bodies implicated in two locations in Congo and Australia in the Global South through the lens of performance studies and critical theory.
New futures health trainers: an impact assessment

Although the health of the UK population has improved significantly over the last century, inequalities in health still exist, with some of Britain’s biggest killers being ‘preventable’ illnesses. The 2004 white paper ‘Choosing Health: Making Healthy Choices Easier’ aimed to introduce initiatives to reduce inequalities in health. One such initiative was ‘Health Trainers’ – a new role staffed by individuals drawn from and based in deprived areas. This role aimed to offer people in deprived communities practical advice about health improvement, and to facilitate access to health services This report aims to examine the impact of introducing the ‘New Futures Health Trainer’ role into criminal justice settings in terms of: a) Training for the Health Trainer Tutors/the development of the Health Trainer training course b) The impact of the training on the New Futures Health Trainers c) The organisational consequences of the role d) The impact of New Futures Health Trainers on clinical outcomes for prisoners/offenders on probation, and e) A brief examination of the relationship between ‘early adopter’ sites for Health Trainers in the community, and the prison/probation equivalent
Elderly Women with Hip Fractures

This study examined the functional and psychosocial characteristics of 100 community-dwelling older women recovering from hip fractures. The greater number of pre-fracture health conditions reported by the women, the lower they rated their post-fracture ADL recovery. The more stress, depression, and help received from informal network members, the poorer the women s perceived recovery. The greater their feelings of attachment to their informal network, the higher the women rated their ADL and overall recovery. Discussion focuses on the role of psychosocial factors in the recovery process.
Fast Sparse Dynamic Time Warping

Dynamic time warping (DTW) has been applied to a wide range of machine learning problems involving the comparison of time series. An important feature of such time series is that they can sometimes be sparse in the sense that the data takes zero value at many epochs. This corresponds for example to quiet periods in speech or to a lack of physical activity. However, employing conventional DTW for such sparse time series runs a full search ignoring the zero data. Sparse dynamic time warping (SDTW) was previously developed which yields the exact DTW solution while reducing the time complexity by the order of a suitably defined sparsity ratio.This paper focuses on the development and analysis of a fast approximate algorithm for dynamic time warping based on the SDTW framework. We call this fast sparse dynamic time warping (FSDTW). This study includes numerical experiments which compare the performance and complexity of FSDTW with DTW, SDTW and other algorithms that approximate DTW for sparse time series. It is shown that FSDTW reduces the time complexity relative to SDTW by the order of the sparsity ratio with negligible error relative to the exact DTW distance.