Miracle-dz/UniFAR-FTUs huggingface dataset:
Utilizing United States Coast Guard Data to Calculate Incidence Rates and Identify Risk Factors for Occupational Fishing Injuries in New Jersey

ABSTRACT Commercial fishing has high rates of work-related injury and death and needs preventive strategies. Work-related fatal and nonfatal injury rates for New Jersey (NJ) commercial fishermen who suffered unintentional traumatic injuries from 2001 to 2007 are calculated using data from the United States Coast Guard (USCG) Marine Safety and Pollution Database and estimated denominator data. Fatalities were compared to those ascertained by the NJ Fatality Assessment Control and Evaluation (FACE) surveillance system. For the study years, 225 nonfatal injuries and 31 fatal injuries were reported. Among nonfatal injuries, the causes by frequency were fall onto surface, crushed between objects, struck by moving object, line handling/caught in lines, collision with fixed objects, fall into water, and other noncontact injuries. The distribution of fatal injuries differed, with the most frequent cause as crushed between objects. Falls into water and several noncontact injuries accounted for most of the other fatalities. The large majority (96%) of nonfatal injuries were contact injuries, whereas only 68% of fatalities were classified as contact. The overall incidence rate of nonfatal injuries was 1188 per 100,000 full-time equivalents (FTEs) per year. The rate varied considerably by year, from a low of 286 per 100,000 FTEs in 2001 and 2007 to 3806 per 100,000 FTEs in 2003. The overall occupational fatality rate over the period 2001–2007 was 164 per 100,000 FTEs per year. These results can aid in targeting the commercial fishing industry for injury prevention strategies and interventions, especially for falls, crushing injuries, and drownings.
Prevention of Occupational Respiratory Symptoms Among Certified Safe Farm Intervention Participants

ABSTRACT Certified Safe Farm (CSF) is a multifaceted intervention including clinical Occupational and wellness screening, education, and on-farm safety audits with set safety standards, and performance incentives. Five years of respiratory health outcomes are reported in 150 CSF intervention farmers and 158 matched controls. Standardized health interviews and occupational histories were analyzed with descriptive statistics to determine prevalence rates. There was a 100% response rate from the standardized telephone interviews, and respectively a 94% and 89 % response rate from the self-administered occupational health history questionnaire for the CSF intervention and the comparison population. The overall rate for occupational respiratory conditions was 17/100 person-years. At baseline there was no difference between the prevalence of respiratory symptoms between the CSF and control groups. However, over the course of the intervention, the CSF farmers increased their use of personal protective respiratory equipment at work, and experienced fewer episodes of acute symptoms of organic dust toxic syndrome (ODTS). The Certified Safe Farm intervention appeared to affect increased use of respiratory protection and decreased symptoms of ODTS.
Catalytic Hydrotreatment of Humins in Mixtures of Formic Acid/2-Propanol with Supported Ruthenium Catalysts.

The catalytic hydrotreatment of humins, which are the solid byproducts from the conversion of C6 sugars (glucose, fructose) into 5-hydroxymethylfurfural (HMF) and levulinic acid (LA), by using supported ruthenium catalysts has been investigated. Reactions were carried out in a batch setup at elevated temperatures (400 °C) by using a hydrogen donor (formic acid (FA) in isopropanol (IPA) or hydrogen gas), with humins obtained from d-glucose. Humin conversions of up to 69 % were achieved with Ru/C and FA, whereas the performance for Ru on alumina was slightly poorer (59 % humin conversion). Humin oils were characterized by using a range of analytical techniques (GC, GC-MS, GCxGC, gel permeation chromatography) and were shown to consist of monomers, mainly alkyl phenolics (>45 % based on compounds detectable by GC) and higher oligomers. A reaction network for the reaction is proposed based on structural proposals for humins and the main reaction products.
The combination of endoglin and FIB-4 increases the accuracy of detection of hepatic fibrosis in chronic hepatitis C patients

Background and aim: In patients infected with chronic hepatitis C virus, liver biopsy is the gold standard method of staging fibrosis. Different combinations of serum markers attempted to correlate with hepatic fibrosis in place of liver biopsy and have shown encouraging results. The aim of our study is to evaluate the diagnostic value of endoglin and FIB-4 as non-invasive markers of hepatic fibrosis in HCV patients. Methods: We estimated serum endoglin & FIB-4 index in 40 infected chronic hepatitis C patients. Histological staging of hepatic fibrosis was done according to the METAVIR scoring system. Results: Both endoglin and FIB-4 index showed positive correlation with age and aspartate transaminase and inverse correlation with albumin. The diagnostic performance determined by AUROCs for early fibrosis (≤F2), was 0.868 for endoglin and 0.887 for FIB-4, at cut off va- lues of 5.5 & 0.98 with sensitivity of 64.3% & 82.1%, and specificity of 100% & 85% respectively. For ad-vanced fibrosis (>F2), the AUROC was 0.98 for endoglin and 0.967 for FIB-4, obtained at cut off values of 6.29 & 1.6, with sensitivity of 100% & 91.7%, and specificity of 89.3% & 92.9%, respectively. Conclusion: Both serum endoglin and FIB-4 index are fairly accurate in differentiating stages of hepatic fibrosis; their combination in a single equation enhanced the accuracy of fibrosis detection in chronic HCV patients.
Occupational Accidents with Agricultural Machinery in Austria

ABSTRACT The number of recognized accidents with fatalities during agricultural and forestry work, despite better technology and coordinated prevention and trainings, is still very high in Austria. The accident scenarios in which people are injured are very different on farms. The common causes of accidents in agriculture and forestry are the loss of control of machine, means of transport or handling equipment, hand-held tool, and object or animal, followed by slipping, stumbling and falling, breakage, bursting, splitting, slipping, fall, and collapse of material agent. In the literature, a number of studies of general (machine- and animal-related accidents) and specific (machine-related accidents) agricultural and forestry accident situations can be found that refer to different databases. From the database Data of the Austrian Workers Compensation Board (AUVA) about occupational accidents with different agricultural machinery over the period 2008–2010 in Austria, main characteristics of the accident, the victim, and the employer as well as variables on causes and circumstances by frequency and contexts of parameters were statistically analyzed by employing the chi-square test and odds ratio. The aim of the study was to determine the information content and quality of the European Statistics on Accidents at Work (ESAW) variables to evaluate safety gaps and risks as well as the accidental man-machine interaction.
Bridging the gap between learning and practice: from where we were to where we are now

Cornwall has implemented significant changes to the way that it delivers its safeguarding adults training. This paper outlines the benefits of combining safeguarding adults, the Mental Capacity Act 2005 (HM Government, 2005a) and equality and diversity training within a human rights framework. It examines the notion of learning transfer and considers how the design and delivery of training can improve the transfer of learning into practice. Finally, it highlights the importance of a receptive workplace culture to promote effective learning transfer.
Long-Term Prognosis of Cerebral Vein and Dural Sinus Thrombosis

The purpose of this study was to analyze the long-term mortality, functional recovery and long-term complications of cerebral vein and dural sinus thrombosis (CVDST) admitted to Portuguese hospitals. A follow-up of symptomatic CVDST admitted to Portuguese hospitals since 1980 was performed. Fifty-one patients (retrospective cases) were re-evaluated during 1996; 91 consecutively admitted patients from 6/1995 to 6/1998 were followed up to 1999. In 1996, 4 (8%) of the retrospective cases had died (3 patients died in the acute phase), 4 (8%) could not be reached, 33 (64%) had recovered completely (Rankin 0 or 1) and 3 (6%) were dependent. The prospective cases had a mean follow-up of 1 year: 6 (7%) patients died in the acute phase, one (1%) died during follow-up, 75 (82%) recovered completely, and only 1 (1%) was dependent. For the prospective cases, worsening after admission (OR = 18.2; 95% CI = 2.9–112.4) and encephalopathy as the presenting syndrome (OR = 7.1; 95% CI = 1.2–40.9) predicted death or dependency, while absence of aphasia (OR 6.7, 95% CI = 1.6–33) and no worsening after admission (OR = 5.9; 95% CI = 1.6–20) predicted total recovery. During follow-up of the prospective cases, 4 (5%) patients had thrombotic events, 8 (10%) patients experienced seizures, 9 (11%) complained of severe headaches and 1 patient suffered severe visual loss. The long-term functional prognosis of patients with CVDST was fairly good with complete recovery in the majority of cases. However, these patients had a moderate risk of further thrombotic events and seizures.
Folate conjugated phosphorylcholine-based polycations for specific targeting in nucleic acids delivery

Folic acid has been investigated as a targeting ligand for imaging and therapeutic agent for over a decade; however, studies on its use in targeting of nonviral gene or nucleic acids delivery systems are sparse. This study assesses potential application of a new folic acid conjugate with aminomethacrylate–phosphoryl-choline based copolymer (DMAEMA-MPC–FA) as a targeting gene delivery vector. The folate-conjugated polymers produce colloidally stable polyplexes with a particle size <200 nm and demonstrate the ability to protect DNA from enzymatic degradation to a certain extent. In cells that overexpress folate receptors (MCF-7 and KB cultures), the conjugated systems show a folate-specific association and achieved significantly enhanced transfection efficiency, compared to the nonconjugated control, with a dramatically reduced nonspecific cellular association. The transfection enhancement is achieved without a corresponding increase in cellular association, suggesting that an internal cellular trafficking of folate-conjugated system may be altered, resulting in an increased transfection efficacy. In summary, a new folate-conjugated aminomethacrylate–phosphorylcholine copolymer is capable of forming colloidal complexes with DNA, modulating their specific cell uptake and improving the level of cell transfection in folate expressing cells.
Frequency and prognostic value of D alloantibodies after D‐mismatched allogeneic hematopoietic stem cell transplantation after reduced‐intensity conditioning

BACKGROUND: Due to the fact that the ABO and D system is inherited independently from the HLA system, approximately 40% of allogeneic hematopoietic stem cell transplants (HSCT) are performed across the blood group barrier. Reports on the development of de novo anti‐D in patients undergoing reduced‐intensity conditioning (RIC) followed by D‐mismatched allogeneic HSCT are rare. The objective of this study was to evaluate the frequency of anti‐D alloimmunization after D‐mismatched HSCT following RIC and its prognostic impact on transplant outcome.
A Longitudinal Study of Adolescent Growth

ric data, in terms of facts per cubic centimetre, than any equivalent volume. This 12th edition has built on the proved worth of its predecessors by the addition of a chapter on resuscitation and by extensive refurbishment of other sections. It now covers most paediatric emergencies, infections and immunisation, neonatalogy, nutrition, fluid and electrolyte treatment, prescribing, investigations, developmental paediatrics and sundry other topics, all in the space of 300 pages. This is achieved by a condensed but careful layout on good white paper, though in places the print is so small as to tax the presbyopic. Nearly 30 contributors are listed-an impressive parade of the paediatric talent of Birmingham. The multiplicity of authors results in variations of approach, some favouring a more discursive style but only a few giving references. The scope of the book is vast but the depth is variable, reflecting the expertise and influence of each author. Some sections are rather sketchy, and others are more detailed and academic, sometimes well beyond the needs of the busy doctor in a general hospital. A book that is such a 'Jack of all trades' cannot hope to master them all with equal success. The section on prescribing is particularly good with drug dosages set out with space and clarity. The sections on neonatology and developmental paediatrics, however, are so condensed that a person working in these areas would also need a more specialist text. Indeed one wonders if the cursory outline of developmental paediatrics sits happily in what is basically a 'hospital' book. The new house officer will look in vain for guidance on procedures, a common source of anxiety for the newcomer to paediatrics, but once the drip is up he or she can find a wealth of advice on what to put through it. The chapter on nutrition contains much useful data and good sense. The list of voluntary organisations and the advice on cot death add some humane leavening to an essentially clinical loaf. The brief section on burns could be improved by inclusion of a percermage chart for surface area and a firmer recommendation for analgesia. One important point that might be questioned is the defmiition of a glucose concentration of 1 5 mmol/l as the threshold for intervention in neonatal hypoglycaemia, which in the light of recent research is surely too low. There is also confused advice on pertussis immunisation together with an outdated schedule-the new one was introduced just as the book went to print. Inevitably such a wide ranging book has points one can quibble over; however, the general standard of information and advice is excellent. The vade-mecum is a bargain at £13-95. Its portability is less relevant where white coats are not the fashion, but puts lady doctors with handbags at a definite advantage.
Recruitment Procedures of EPIC-Germany

EPIC is among the largest cohort studies, with approximately 475,000 study participants, on the etiological influence of diet and chronic diseases. During a 4-year recruitment period, two German EPIC centers, located in Heidelberg and Potsdam, aimed to recruit a total of 60,000 study participants from the local populations. The recruitment process was based on addresses from general population registries and started 4–5 weeks in advance with an initial invitation by mail to the basic examination for this study. Subjects not responding within 2 weeks were reminded. In Potsdam, this was done by mail and telephone, and in Heidelberg by telephone. During the recruitment phase, from 1994 to 1998, 53,162 subjects in total were examined for the cohort studies in Heidelberg (n = 25,546) and Potsdam (n = 27,616). The participation rate, compared to the invited number of subjects, was 22.7% in Potsdam and 38.3% in Heidelberg, with a considerable variation by municipality and gender. A comparison with data from the National Health Survey 1991/1992 revealed that the cohort populations were of higher socio-economic status and were healthier than the source population. We concluded that the selective participation would help to ensure high maintenance of the cohort during active follow-up. Selective participation does not harm etiological conclusions because disease associations are derived internally as relative risk. The relative risk estimates can be used to calculate population-attributable risk and preventable proportion, based on exposure prevalence derived by surveys and other studies.
CRHBP polymorphisms predict chronic pain development following motor vehicle collision

Abstract Musculoskeletal pain (MSP) is a common sequela of traumatic stress exposure. While biological factors contributing to chronic MSP after motor vehicle collision (MVC) have traditionally focused on tissue injury, increasing evidence suggests that neuro/stress/immune processes mediated by stress system activation may play a more dominant role. In a previous study, we found that genetic variants in the hypothalamic–pituitary–adrenal (HPA) axis–related gene FKBP5 influence vulnerability to persistent MSP 6 weeks after MVC. In the present cohort study (n = 855), we evaluated whether genetic variants in several other important HPA axis–related genes, including the glucocorticoid receptor (NR3C1), corticotropin-releasing hormone receptor R1 (CRHR1), and corticotropin-releasing hormone-binding protein (CRHBP), influence risk of chronic MSP over time after MVC. Genetic polymorphism rs7718461 in the CRHBP gene showed significant association (P = 0.0012) with overall pain severity during the year after MVC in regression models controlling for multiple comparisons. Two additional CRHBP alleles in high linkage disequilibrium with rs7718461 also showed trend-level significance. In secondary analyses, a significant interaction between this CRHBP locus (minor allele frequency = 0.33) and time was observed (P = 0.015), with increasing effect observed over time following trauma. A significant CRHBP × FKBP5 interaction was also observed, with substantially increased MSP after MVC in those with a risk allele in both genes compared with either gene alone. The results of this study indicate that genetic variants in 2 different HPA axis genes predict chronic MSP severity following MVC and support the hypothesis that the HPA axis is involved in chronic post-MVC MSP pathogenesis.
Psychological factors predicting stress symptoms: Metacognition, thought control, and varieties of worry

Abstract This study tested predictions of the metacognitive model of post-traumatic stress disorder (Wells, 2000) concerning relationships between stress symptoms and maladaptive control of thoughts. We tested the hypothesis that the tendency to use worry as a means of controlling thoughts will be positively predictive of stress symptoms. In doing so, overlaps with symptomatic worry, stress symptoms, and stress exposure at time 1 was controlled. One hundred and ten (110) college students were assessed twice, over a three-month period. Consistent with predictions, use of worry as a thought control strategy made a significant and independent contribution to the prediction of stress symptoms. The findings provide further support for Wells’ metacognitive model of stress reactions.
Solvent-Free Mechanochemical Synthesis of Nitrogen-Doped Nanoporous Carbon for Electrochemical Energy Storage.

Nitrogen-doped nanoporous carbons were synthesized by a solvent-free mechanochemically induced one-pot synthesis. This facile approach involves the mechanochemical treatment and carbonization of three solid materials: potassium carbonate, urea, and lignin, which is a waste product from pulp industry. The resulting nitrogen-doped porous carbons offer a very high specific surface area up to 3000 m2 g-1 and large pore volume up to 2 cm3 g-1 . The mechanochemical reaction and the impact of activation and functionalization are investigated by nitrogen and water physisorption and high-resolution X-ray photoelectron spectroscopy (XPS). Our N-doped carbons are highly suitable for electrochemical energy storage as supercapacitor electrodes, showing high specific capacitances in aqueous 1 m Li2 SO4 electrolyte (177 F g-1 ), organic 1 m tetraethylammonium tetrafluoroborate in acetonitrile (147 F g-1 ), and an ionic liquid (1-ethyl-3-methylimidazolium tetrafluoroborate; 192 F g-1 ). This new mechanochemical pathway synergistically combines attractive energy-storage ratings with a scalable, time-efficient, cost-effective, and environmentally favorable synthesis.
Mapping the Free Energy of Lithium Solvation in the Protic Ionic Liquid Ethylammonuim Nitrate: A Metadynamics Study.

Understanding lithium solvation and transport in ionic liquids is important due to their possible application in electrochemical devices. Using first-principles simulations aided by a metadynamics approach we study the free-energy landscape for lithium ions at infinite dilution in ethylammonium nitrate, a protic ionic liquid. We analyze the local structure of the liquid around the lithium cation and obtain a quantitative picture in agreement with experimental findings. Our simulations show that the lowest two free energy minima correspond to conformations with the lithium ion being solvated either by three or four nitrate ions with a transition barrier between them of 0.2 eV. Other less probable conformations having different solvation pattern are also investigated.
Mountaineering as affect regulation: the moderating role of self-regulation strategies

Abstract We investigated the change in mountaineers' affect from pre- to post-mountain route and the moderating role of self-regulation strategies in this process. First, we hypothesized that engagement in a high-risk sport such as mountaineering would lead to a decrease in negative affect and an increase in positive affect and that this affect regulation would be moderated by self-regulation strategies (escape from self-awareness and compensation). Second, we predicted that the self-regulation affect process would be specifically associated with high-risk sport rather than sport generally. One hundred and five mountaineers and 73 judokas completed the Risk and Excitement Inventory and the Positive and Negative Emotions Scale before and after completing their activity (mountain route or judo fight). Regression analyses revealed that anxiety significantly decreased from pre- to post-mountain route and that the self-regulation of escape from awareness yielded a significantly greater anxiety decrease. No such interaction emerged for the compensation strategy and no effects were revealed for judokas. Results are discussed in terms of the specificity of the high-risk sport domain in its ability to serve an affect regulation function for those individuals who seek to escape from self-awareness.
Detection of dengue virus in sera of Brazilian blood donors

BACKGROUND: Dengue is the most important arboviral disease in the world. Dengue viruses (DENVs) have produced huge outbreaks in Brazil in the past 25 years with more than 5 million reported cases. During these epidemics, asymptomatic individuals infected with DENV could donate blood and serve as a source of virus dissemination in the community. Here, we studied the circulation of DENV in healthy individuals during an epidemic outbreak.
Psychometric evaluation of the Social Interaction Phobia Scale

Abstract The present study evaluated the psychometric properties of a novel measure of social anxiety symptoms, the Social Interaction Phobia Scale (SIPS), as a stand-alone item set, using an undergraduate sample (N=512). The 14-item SIPS has three subscales assessing Social Interaction Anxiety, Fear of Overt Evaluation, and Fear of Attracting Attention. Confirmatory factor analyses replicated the three-factor structure for the SIPS originally reported by Carleton et al. All SIPS scores demonstrated good internal consistency. The convergent validity of the SIPS was supported by strong and positive correlations between all SIPS scores and measures of social anxiety and fear of evaluation; the finding that the relationships between all SIPS scores and a social anxiety measure were stronger than relationships between all SIPS scores and measures of other constructs supported the discriminant validity of the SIPS. Results suggest that the SIPS possesses excellent psychometric properties.