Miracle-dz/UniFAR-FTUs huggingface dataset:
The impact of community-based integrated HIV and sexual and reproductive health services for youth on population-level HIV viral load and sexually transmitted infections in Zimbabwe: protocol for the CHIEDZA cluster-randomised trial

Background Youth have poorer HIV-related outcomes when compared to other age-groups. We describe the protocol for a cluster randomised trial (CRT) to evaluate the effectiveness of community-based, integrated HIV and sexual and reproductive health services for youth on HIV outcomes. Protocol The CHIEDZA trial is being conducted in three provinces in Zimbabwe, each with eight geographically demarcated areas (clusters) (total 24 clusters) randomised 1:1 to standard of care (existing health services) or to the intervention. The intervention comprises community-based delivery of HIV services including testing, antiretroviral therapy, treatment monitoring and adherence support as well as family planning, syndromic management of sexually transmitted infections (STIs), menstrual health management, condoms and HIV prevention and general health counselling. Youth aged 16–24 years living within intervention clusters are eligible to access CHIEDZA services. A CRT of STI screening (chlamydia, gonorrhoea and trichomoniasis) is nested in two provinces (16 of 24 clusters). The intervention is delivered over a 30-month period by a multidisciplinary team trained and configured to provide high-quality, youth friendly services. Outcomes will be ascertained through a population-based survey of 18–24-year-olds. The primary outcome is HIV viral load <1000 copies/ml in those living with HIV and proportion who test positive for STIs (for the nested trial). A detailed process and cost evaluation of the trial will be conducted. Ethics and Dissemination The trial protocol was approved by the Medical Research Council of Zimbabwe, the Biomedical Research and Training Institute Institutional Review Board and the London School of Hygiene & Tropical Medicine Research Ethics Committee. Results will be submitted to open-access peer-reviewed journals, presented at academic meetings and shared with participating communities and with national and international policy-making bodies. Trial Registration https://clinicaltrials.gov/: NCT03719521
BATMAN Adv. Mesh network emulator

Resumen We introduce a new network emulator environment, developed by our research group, called the BAMNE. Our emulator is designed specifically to allow working with BATMAN Adv. mesh protocols. This mesh network emulator facilitates doing tests with BATMAN Adv. protocol and evaluate and debug mesh networks. The emulated wireless equipment runs in virtual machines using VirtualBox, and the wireless links are simulated with Vde-switch. Vde-switch allows simulating impediments in the link transmission like loss of bits, packet loss, delay. To construct the emulation environment, python language was used.
P‐47: Hold‐Type Display Motion Blur Reduction with Spatial Compensation

Motion blur reduction technology becomes more and more important in LCD TV applications. Recently, black data insertion, scanning backlight, LED local dimming, and high frame rate driving with ME/MC are main technologies for motion blur reduction. Those technologies improve motion blur by reducing temporal integration time of human visual system. We proposed a novel method to reduce motion blur by mapping the designed optical waveform back to the spatial position on the display. By this proposed method, we can improve the motion picture response time without increasing frame rate and decreasing the luminance of display. By simple motion estimation (simply estimating the motion speed and direction) and mapping the designed optical waveform back to the spatial position, the complex computing hardware can be saved and the requirement for LC panel can be reduced.
production by endothelial cells

Mast cells are constituent cells of vascular tissue and their numbers are increased in atheroscie- rotic vessels. To gain insight into the role ofmast cells in vascular inflammation, the effect of mast cell granules (MCG) on endothelial cell production of interleukin-6 (IL-6) was examined. Human umbilical vein endothe- lial cells (HUVEC) were cultured with lipopolysaccha- ride (LPS) in the presence or absence ofrat peritoneal MCG and IL-6 production was assayed by enzyme- linked immunosorbent assay. The interaction of MCG with HUVEC in culture was examined by electron ml- croscopy (EM). The EM studies revealed that MCG are internalized by HIJVEC and appear intact even after 24 h in culture. Unactivated HUVEC produced little or no IL-6 either in the presence or absence of MCG. Treatment of HUVEC with LPS stimulated IL-6 production in a dose- and time-dependent fashion. Addition of MCG to LPS-activated HUVEC resulted in the potentiation ofIL-6 production at all LPS doses. MCG-induced enhancement of IL-6 production was evident even at a mast cell-to-endothelial cell ratio of 1:32. The enhancement of IL-6 production by MCG was also seen when tumor necrosis factor a was used as an activator. Although potentiation was evident when MCG were added 6 h before or after LPS stimulation, the maximum effect was noted when MCG and LPS were added simultaneously. MCG-mediated enhance- ment of IL-6 production was abrogated by pretreat- lag MCG with protease inhibitors. Although MCG pro- teases potentiate IL-6 production by HUVEC, they do not degrade secreted IL-6. These results demonstrate that MCG interact with endothelial cells and modulate the production ofan important inflammatory cytokine. J. Leukoc. Biol. 62: 210-216; 1997.
A Contribution to the Analysis of the Performance of the Gas Turbine Using Simulation

The aim of this paper is to demonstrate the successful application of system dynamic simulation modelling for studying performance dynamics of the gas turbine in load conditions. This study is conducted using an example of load of synchronous generator. Gas turbine at the load of synchronous generator is a complex non-linear system, which needs to be systematically investigated as a unit consisting of a number of subsystems and elements, which are linked by cause-effect (UPV) feedback loops (KPD), both within the propulsion system and with the relevant surrounding. In this paper the authors will present an efficient application of scientific methods for the study of complex dynamic systems called qualitative and quantitative simulation System Dynamics Methodology. This methodology will allow generation and application of higher number and types of simulation models of the observed elements. Furthermore, this methodology will allow continuous computer simulation that will significantly contribute to the acquisition of new knowledge about the nonlinear characteristics of performance dynamics of turbine and generator system in the process of designing and learning. Gas turbine will be presented by a set of non-linear differential equations, after which mental-verbal structural models and flowcharts in System dynamics symbols will be produced, and the performance dynamics in load condition will be simulated in POWERSIM simulation language.
The effect of a unilateral sacroiliac joint manipulation on muscle activity and force output in the posterior oblique sling muscles

Objective: The effects of spinal manipulation have been well documented, however, current literature poses a gap regarding the neurophysiological mechanisms responsible for these effects. Further evidence is required in order to uncover the specific neurophysiological mechanisms of spinal manipulative therapy (SMT) and its effect on muscle activity. The study aimed to investigate the immediate effect of a unilateral sacroiliac joint (SIJ) manipulation compared to a control on muscle activity (EMG in mV) and maximum voluntary force output (dynamometer in kg) in the posterior oblique sling (POS) muscles in asymptomatic participants. Methods: A randomised, controlled, pre-test, post-test design allowed for 34 participants, aged 18-45 years old, with joint dysfunction at the SIJ to be allocated to either a manipulation or a control group. Force output and muscle activity of the gluteus maximus (GM) and latissimus dorsi (LD) muscles were measured before and after the intervention. IBM SPSS was used to analyse the data with significance set at (p=0.05). Independent samples t-tests were used to determine significance within, and between, the groups, and Pearson correlation analysis looked for correlations between the muscles in the two slings. Results: There were no significant differences observed between the control and intervention groups for age (p=0.355), gender (p=0.688), race (p=0.338), BMI (p=0.142), and the side of joint fixation (p=0.473). The intra-group analysis and intergroup analysis showed no significant differences for peak amplitude and mean muscle activity of the muscles of the POS when assessed for intra- or intergroup comparisons. A significant difference between pre and post maximum force output in the right GM for both groups (intervention: p=0.016; control: p=0.030), and in the right LD for the control group only (p=0.032), was noted. However, there was no significant difference between group results for any muscle in terms of force output when assessed for intergroup comparisons. Conclusion: The results of this study showed no treatment effect of SIJ manipulation on the muscles of the POS in asymptomatic participants. Consideration should be given to the way SMT is administered, the type of sham intervention used and the protocol followed to elicit maximum voluntary isometric contraction (MVIC).
P RELIMINARY CONCEPT OF G ENERAL INTELLIGENT NETWORK (GIN) FOR BRAIN - LIKE INTELLIGENCE

Preliminary concept of AGI for brain-like intelligence is presented in this paper. The solution is mainly in two aspects: ﬁrstly, we combine information entropy and generative network (GAN like) model to propose a paradigm of General Intelligent Network (GIN). In the GIN network, the original multimodal information can be encoded as low information entropy hidden state representations (HPPs), which can be reverse parsed by the contextually relevant generative network into observable information. Secondly,we propose a generalized machine learning operating system (GML system), which includes an observable processor (AOP), an HPP storage system, and a multimodal implicit sensing/execution network. Our code will be released at https://github.com/ggsonic/GIN
A Contour Approach to Thinning Algorithms

Thinning algorithms are widely used in many image processing tasks. Many thinning algorithms were proposed but they usually tend to process all image pixels in every iteration. Two approaches to contour thinning are described and a short discussion about their features is given. These approaches can be implemented as sequential or parallel algorithms with different deletion rules. Results of comparison and analysis are presented in paper.
How Media Influence the Intergroup Relationships Between LGBT and the Non- LGBT Community in China

The life of the LGBT community is filled with challenges, which might have negative influences on their mental and physical well-being. While certain countries are improving equal rights for the LGBT community through legislation, others are lagging. For example, the Chinese LGBT community fights for their rights but often failed. Drawn upon empirical evidence, diverse representations of the LGBT community on media can increase public understanding and enhance inclusive attitudes towards this group. Thus, this project aims to examine how these benefits generated from media representations can be applied to the intergroup relationships between LGBT and non-LGBT communities in
THE ACUTE EFFECT OF EXERGAME ON HAEMODYNAMICS RESPONSES IN SEDENTARY AND ACTIVE YOUNG ADULTS

The purpose of this study was to investigate the effects of exergame (Nintendo ® WiiFi™) on haemodynamics responses. Twenty participants with age 18-25 years old were participated in this study and were divided into two groups; active group (AG; n=10) and sedentary group (SG; n=10). On the experimental day, after resting for 10 min., participants performed exercise by using seven games of Nintendo Wii for 20 min. and recovery for 5 min. The haemodynamic variables including heart rate (HR), stroke volume (SV), cardiac output (CO), cardiac index (CI), ejection fraction (EF), and systemetic vascular resistance (SVR) were recorded in a real time on neck, sternum, rib closet to V6, and back by non-invasive technique (Physioflow ® ) throughout the experiment. The results showed that at rest, during exercise, and recovery period, the participants in AG had better blood circulation than those in SG, but no significant difference between groups. However, the value of EF in AG at recovery period was higher than that in SG and showed significant difference ( p <0.05) between groups. Therefore, exercise by exergame can improve the cardiac function in young adults. The AG had more responses to exergames than SG in some haemodynamics parameters. (Journal of Sports Science and Technology 2015;15(1): 121-130 )
Body Composition as a Modulator of Bone Health Changes in Patients with Inflammatory Bowel Disease

Background: Bone impairment of multifactorial etiology is a common feature in inflammatory bowel disease (IBD). Body composition parameters, which might be selectively modified in these patients, are important determinants of bone strength. Our aim was to investigate the relationship between components of body composition and bone parameters in IBD patients. Methods: This is a cross-sectional, retrospective study including 80 IBD patients (43 women, 37 men). Lumbar spine (LS), femoral neck (FN) and whole body DXA scans were performed to analyze regional bone mineral density (BMD), as well as body composition, including appendicular skeletal muscle mass index (ASMI), total and visceral fat mass (VAT). Trabecular bone score (TBS) was assessed using iNsight Software. Results: Twenty (25%) IBD patients had inadequate LS-BMD z scores (<=−2DS). Lean mass (LM) was a significant determinant of LS-BMD, after adjusting for age, gender, BMI and fat mass (p < 0.01), while fat mass% remained associated with FN-BMD (p < 0.01). TBS correlated positively with BMI (r = 0.24, p < 0.05), LS-BMD (r = 0.56, p < 0.001), ASMI (r = 0.34, p < 0.001) and negatively with VAT/total fat% (r = −0.27, p < 0.05). Multivariate analysis showed that ASMI, LS-BMD (positively) and VAT/total fat% (negatively) were independently associated with TBS. Conclusions: In IBD patients, skeletal muscle mass and fat percentage and distribution are important factors associated with bone health.
Limitations and corrections in measuring dynamic characteristics of structural systems

The work deals with limitations encountered in measuring the dynamic characteristics of structural systems. Structural loading and response are measured by transducers possessing multiple resonant frequencies in their transfer function. In transient environments, the resultant signals from these transducers are shown to be analytically unpredictable in amplitude level and frequency content. Data recorded during nuclear effects simulation testing on structures are analyzed. Results of analysis can be generalized to any structure which encounters dynamic loading. Methods to improve the recorded data are described which can be implemented on a frequency selective basis during the measurement process. These improvements minimize data distortion attributable to the transfer characteristics of the measuring transducers.
Modeling and Simulation of Residential Power Demand Including Transportation

Personal transportation has a significant impact on the residential electric energy usage due to the interaction of alternative fueled vehicles with the electric grid. This phenomenon is projected to grow significantly, as several studies confirm that the market penetration of alternative fueled vehicles will steadily increase in the future.This paper presents a control-oriented model that predicts the daily residential power demand considering multiple energy carriers and different types of alternative fueled vehicles for personal transportation. The model has been used to perform an energy analysis on a large sample of homes with the objective of evaluating the impact of personal transportation on the residential electric power demand. Two penetration levels are considered in the study and the results are evaluated based on several metrics.Copyright © 2015 by ASME
Wimax Performance Impacts in Multi-Cell Deployments

This paper presents the application of the multiple antenna schemes beamforming (BF) and Multiple Input Multiple Output (MIMO) in the broadband wireless access system WiMAX. The evaluation considers the competing performance demands on link robustness and peak data rate. Configurations for both uplink and downlink are discussed. We conclude that future wireless communications will rely on diverse and adaptive multiple antenna schemes to meet their requirements, in particular in the presence of strong co-channel interference.
The Impact of the 13-Valent Pneumococcal Conjugate Vaccine on Otitis Media–Related Antibiotic Use Among Young Children in Tennessee, USA

Abstract Otitis media (OM) is a leading cause of pediatric antibiotic use. Introduction of the 13-valent pneumococcal conjugate vaccine (PCV13) led to reductions in OM among US children, though its impact on OM-related antibiotic use remains unclear. Among 499 683 Tennessee children <2 years of age, the OM-related antibiotic fill rate was stable after PCV13 introduction.
A netnography approach on the daily local-guided shopping tour experiences of travellers: An unexplored facet of the sharing economy

This research explores the travellers’ experience of daily local-guided shopping tours offered in a sharing economy platform-Withlocals using a netnography approach. Reviews of travellers participating in daily local-guided shopping tours in different destinations were gathered, and their content was analysed. As a result, seven main components of experiences of daily-local guided shopping tours revealed: guide, shopping companion, learning, hedonic experience, memorable experience, local interaction, and shop characteristics. The study substantially contributes to the shopping experience and sharing economy literature by providing a deep understanding of travellers’ shopping experiences in the local guided tours organised through sharing economy platforms.
Toward a New Primary Standardization of Radionuclide Massic Activity Using Microcalorimetry and Quantitative Milligram-Scale Samples

We present a new paradigm for the primary standardization of radionuclide activity per mass of solution (Bq/g). Two key enabling capabilities are 4π decay-energy spectrometry using chip-scale sub-Kelvin microcalorimeters and direct realization of mass by gravimetric inkjet dispensing using an electrostatic force balance. In contrast to traditional traceability, which typically relies on chemical separation of single-radionuclide samples, 4π integral counting, and additional spectrometry methods to verify purity, the system described here has both 4π counting efficiency and spectroscopic resolution sufficient to identify multiple radionuclides in the same sample at once. This enables primary standardization of activity concentrations of mixed-radionuclide samples. A major benefit of this capability, beyond metrology, is in assay of environmental and forensics samples, for which the quantification of multiplenuclide samples can be achieved where presently inhibited by interferences. This can be achieved without the need for chemical separations or efficiency tracers, thereby vastly reducing time, radioactive waste, and resulting measurement uncertainty.
Effects on the System, Contents, and Service Quality of e-book User Purchase

Abstract The e-book technology is developing day by day with the expansion of e-ink technology. However, consumers' complaint over contents which are relatively deficient compared to paper book, the issue of compatibility of file between bookstores is not improved as yet. This means that present e-book market needs study in the viewpoint of consumer who intend to accept requirement of market instead of viewpoint of technical development. Thus, this study intends to measure the quality of three main attributes such as system, contents and service based on IS Success Model which compose e-book to identify the influence on readers' purchase intention. Result, System quality is to device purchase intention, and Contents quality is to e-book pruchase intention, it showed a significant damaging effect on. Key Words : e-book, System, Contents, Service, Quality Measure * 이 논문은 2015년도 국가연구장학금(인문사회계)의 지원에 의해 작성되었음** 이 논문은 12th International conference on Economics and Social Sciences 발표 논문을 수정 보완하였음(2015.11.07)Received 30 November 2015, Revised 30 December 2015Accepted 20 January 2016Corresponding Author : Seoung-Ha, Lee(Chung-Ang Univ.) Email: shpoem418@hanmail.netⒸ The Society of Digital Policy & Management. All rights reserved. This is an open-access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0), which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is ISSN: 1738-1916 properly cited.
RRM2 Alleviates Doxorubicin-Induced Cardiotoxicity through the AKT/mTOR Signaling Pathway

Doxorubicin (DOX) is an effective chemotherapeutic agent that plays an unparalleled role in cancer treatment. However, its serious dose-dependent cardiotoxicity, which eventually contributes to irreversible heart failure, has greatly limited the widespread clinical application of DOX. A previous study has demonstrated that the ribonucleotide reductase M2 subunit (RRM2) exerts salutary effects on promoting proliferation and inhibiting apoptosis and autophagy. However, the specific function of RRM2 in DOX-induced cardiotoxicity is yet to be determined. This study aimed to elucidate the role and potential mechanism of RRM2 on DOX-induced cardiotoxicity by investigating neonatal primary cardiomyocytes and mice treated with DOX. Subsequently, the results indicated that RRM2 expression was significantly reduced in mice hearts and primary cardiomyocytes. Apoptosis and autophagy-related proteins, such as cleaved-Caspase3 (C-Caspase3), LC3B, and beclin1, were distinctly upregulated. Additionally, RRM2 deficiency led to increased autophagy and apoptosis in cells. RRM2 overexpression, on the contrary, alleviated DOX-induced cardiotoxicity in vivo and in vitro. Consistently, DIDOX, an inhibitor of RRM2, attenuated the protective effect of RRM2. Mechanistically, we found that AKT/mTOR inhibitors could reverse the function of RRM2 overexpression on DOX-induced autophagy and apoptosis, which means that RRM2 could have regulated DOX-induced cardiotoxicity through the AKT/mTOR signaling pathway. In conclusion, our experiment established that RRM2 could be a potential treatment in reversing DOX-induced cardiac dysfunction.