Miracle-dz/UniFAR-FTUs huggingface dataset:
EX-VIVO ANTIBACTERIAL, PHYTOTOXIC AND CYTOTOXIC, POTENTIAL IN THE CRUDE NATURAL PHYTOCONSTITUENTS OF RUMEX HASTATUS D. DON ZUL

In the present study the crude saponins, crude methanolic extract and subsequent fractions of Rumex hastatus have been evaluated for the cytotoxic potential against brine shrimps and phytotoxic potential against radish. In addition, the antibacterial activity has been evaluated for crude flavonoids (Rh.Fl), saponins (Rh.Sp), crude methanolic extract (Rh.Cr) and resultant fractions of R. hastatus by well diffusion method. In antibacterial assay, the Rh.Fl displayed considerably better activity against all the strains followed by Rh.Sp, which was comparable with positive control. Among the fractions the ethyl acetate (Rh.EaF) and chloroform fractions (Rh.CfF) revealed good zones of inhibition (ZOI). All the test samples were active against Proteus mirabilis, Staphylococcus aureus, Klebsiella pneumoniae and Pseudomonas aeruginosa. The largest ZOI was revealed by Rh.Fl i.e., 34.8 ± 0.72 mm ZOI against Bacillus cereus. The Rh.Sp was more active against Escherichia coli resulting in 34.1 ± 0.49mm ZOI. Similarly against brine shrimps, the Rh.Sp fractions show excellent cytotoxic i.e., 96.76 ± 1.1, 73.86 ± 2.9 and 50.67 ± 1.9% brine shrimps lethality at the concentration of 1000, 100 and 10μg/ml, respectively with the LC50 of 10μg/ml. Among the fractions, Rh.CfF showed remarkable cytotoxicity with LC50 of 65μg/ml. Rh.EaF and Rh.Cr displayed the similar lethality with LC50 of 90μg/ml. The cytotoxicity exhibited by aqueous fraction (Rh.Wtf) and n-hexane fraction (Rh.HxF) was moderate with LC50 of 100μg/ml and 390μg/ml, respectively. The phytotoxicity assay was conducted against radish seeds in which the Rh.Sp exhibited remarkable phytotoxicity i.e., root length inhibition (RLI) (IC50= 9μg/ml) and seeds germination inhibitions (SGI) (IC50= 15μg/ml) which was comparable with the Paraquat act as positive control. Among the fractions Rh.CfF demonstrated outstanding phytotoxic activity i.e., 86.63 ± 0.80, 67.10 ± 1.10 and 45.90 ± 2.90% (IC50 = 23 μg/ml) RLI and 78.68 ± 1.33, 69.92 ± 0.50 and 54.70 ± 1.20% (IC50 = 5μg/ml) SGI at the concentration of 1000, 100 and 10 μg/ml respectively. Rh.EaF demonstrated 85.42 ± 0.20, 63.00 ± 1.90 and 41.33 ± 1.10% (IC50 = 32μg/ml) RLI and 72.00 ± 2.32, 63.76 ± 1.10 and 49.70 ± 1.10% (IC50 = 13μg/ml) SGI at 1000, 100 and 10 μg/ml respectively. The Rh.HxF revealed 82.59 ± 3.20, 61.33 ± 1.90 and 39.33 ± 1.10% (IC50 = 35μg/ml) RLI and 68.00 ± 2.32, 57.53 ± 0.70 and 36.20 ± 0.90% (IC50 = 46 μg/ml) SGI at 1000, 100 and 10 μg/ml respectively. The Rh.Cr and Rh.WtF showed moderate phytotoxicity. Based on the results obtained from the present study it may be inferred that R. hastatus may be an excellent source of natural compounds having antibacterial, anticancer and herbicidal potential.
A Multidisciplinary Approach To Localized Gingival Recession: A Case Report

Background: Many techniques are available for the treatment of gingival recessions. Platelet rich fibrin (PRF) is being used for root coverage and periodontal regeneration with better wound healing. Objective: The purpose of this case report is to present the treatment stages and outcomes of a female patient who referred to our clinic with the complaint of gingival recession. Case Description: A 29-year-old patient with porcelain fused to metal (PFM) restorations on the maxillary incisors, had Miller Class I recession on her left lateral incisor. Initially, Phase I periodontal therapy was performed. One month later, the exposed root surface was covered with PRF and a coronally advanced flap was done. Postoperative healing was uneventful and 2 mm of root coverage was gained. Maxillary incisors were restored with zirconia crown prostheses. During 6 months follow-up no further exposure occured. Practical Implications: PRF is a preferable method enhancing success rates of the operation for recession coverage.
Effects of injection of vitamin D3 on plasma concentrations of vitamin D metabolites and minerals in cows during late pregnant and lactating periods

plasma 1,25 (OH)2D concentrations in the lactating period were significantly lower than those in the pregnant period at 12hr and 1day after the injection. The plasma Ca concentration in the lactating period was also signifi- cantly lower than that in the pregnant period at 1day before the injection. These results suggest that there are no differences in the effects of the vitamin D3 injection between late pregnant and lactating period, al-though the activity of 24,25-dihydroxylase in the lactating period may be increased by the effect of vitamin D3 injected during the late pregnant period.
AOM Online Papers Submission # 11967

Previous research on entrepreneurial teams has failed to settle the controversy over whether team heterogeneity helps or hinders new venture performance. Reconciling this inconsistency, this paper suggests a new conceptual approach to disentangle differential effects of team heterogeneity by modeling two separate heterogeneity dimensions, namely knowledge scope and knowledge disparity. Analyzing unique data on functional experiences of the members of 337 start-up teams, we find support for our contention of team heterogeneity as a two-dimensional concept. Results suggest that knowledge disparity negatively relates to both start-ups’ entrepreneurial and innovative performance. In contrast, we find knowledge scope to positively affect entrepreneurial performance, while it shows an inverse U-shaped relationship to innovative start-up performance. INTRODUCTION It is widely acknowledged that entrepreneurship occurs as a shared effort with new firms more often being created by groups of people than by individuals (Davidsson & Wiklund, 2001; Francis & Sandberg, 2000; Gartner et al., 1994; Kamm et al., 1990; Roberts, 1991). Entrepreneurial teams have recently been identified as an “omnipresent phenomenon” describing “the superior entrepreneurial start-up concept” (Lechler, 2001, p. 264). An emerging, though relatively limited, body of entrepreneurship literature has given ample empirical support to the notion that team start-ups indeed perform better than solo ventures (e.g., Chandler et al., 2005; Chowdhury, 2005; Ucbasaran et al., 2003). Accordingly, the apparent success of entrepreneurial # 11967
Cutaneous Blood Flow Responses by 133 Xenon Washout and a Laser-Doppler Flowmeter

7. Gould OJ, Cu nliffe WJ , Holland KT: Chemotaxis and acne. J Invest Dermatol 68:251, 1977 8. Puhvel SM, Sakamoto M: An in vivo evaluation of the inflammatory effect of purified comedonal components in human skin. J Invest Dermatol 69:401-406, 1977 9. Westphal 0, Luderitz 0 , Bister F:Ober die Extraktion von Bakterien mit Phenol/Wasser. Z Naturforsch 78:148-155, 1972 1.0. Lowry OH, Rosebrough NJ , Farr AL, Randall RJ: Protein measurements with the folic phenol reagent. J Bioi Chern 193:265275, 1951 J 1. Kabat EA, Mayer MM: Cm·bohydrate determination, Experimenta l Immunochemistry. Springfield, Ill , Charles C Thomas, 1971, pp 527528 12. Neoh SH, Rowley D: Quantitative assay of protein antigen of vibrio cholerae involved in the vibriocidal action of antibody and complement. Aust J Exp Bioi Med Sci 49:605-608, 1971 13. Knop J , Rowley D: Antibacterial efficiencies of ovine IgA, IgM, and IgG. J Infect Dis 130:368-373, 1974 14. Marks R, Dawber RPR: Skin surface biopsy: an improved technique for the examination of the horny layer. Br J Dermatol
OPTH_A_224970 2195..2201

Zoraida S Gaurisankar 1 Gwyneth A van Rijn 1 Gregorius PM Luyten 1 Thomas JTP van den Berg 2 1Department of Ophthalmology, Leiden University Medical Center, Leiden, the Netherlands; 2Institute for Neuroscience, Royal Netherlands Academy of Arts and Sciences, Amsterdam, the Netherlands Purpose: To investigate the effect of refractive correction on straylight. Patients and methods: Straylight values were measured with the C-Quant (Oculus Optikgeräte, GmbH, Wetzlar, Germany) in 1) near-emmetropic eyes (n=30) with various negative powered refractive lenses and in 2) myopic eyes (n=30) corrected with prescribed eyeglasses and contact lenses. The straylight measurements in each group were compared in the different conditions. Results: In the near-emmetropic group, a significant effect (p<0.001) of each added negative diopter was found to increase straylight values with 0.006 log-units. In the second group, no significant correlation with type of correcting lens was found on straylight values. Conclusion: Refractive correction with high minus power (contact) lenses result in subtle increase of straylight values. These changes are relatively small and do not lead to visual disability in a clinical setting.
0 Powerful CEOs and Stock Price Crash Risk

We find that firms with powerful CEOs lead to stock price crash. The effects of real and accrual earnings management, and CEO pay dominance on crash risk are more pronounced for firms with powerful founder CEOs. The effects of tax avoidance, CFO option incentives and CEO overconfidence on crash are more pronounced for firms with powerful CEOs. The takeover index, mitigates stock price crash for firms with non-powerful CEOs. Product market competition does not attenuate the impact of CEO power on crash. Our findings provide new insights on the importance of CEO power in driving stock price crash risk. JEL Classifications: G3; G12; G32
Motion Segmentation Based on Fusion of MSRF Segmentation and Canny Operator

One of the main problems of motion segmentation is occluding, which can make the segmentation result inaccurate. In order to solve this problem, we have to use extra information. In this paper, we proposed a new fusion segmentation method, in which a Canny operator is used to get the edge information from one frame of an image sequence; then this edge information will be fused with the result of motion segmentation. By simulation, we can find that the fusion method can get the real edge of the moving object in the image sequence.
Effect of Climate Change on Soil Global Microorganisms

Given that it is generally accepted that the climate is changing, it is essential to investigate the effects that changes in climate parameters (temperature, precipitation) will have on the soil C cycle (through changes in inputs and outputs) and on the activity of soil microorganisms. Soils provide essential ecosystem services such as primary production, regulation of biogeochemical cycles and their consequences on climate, water filtration, resistance to diseases and pests, and regulation of above-ground biodiversity. Concomitantly, soils are exposed to many anthropogenic threats. Scientific and technological knowledge on soil biodiversity and functioning in relation to ecosystem services is required for reaching such a goal. Soils host a huge diversity of microbes (archaea, bacteria, and fungi) and fauna (protozoa, microarthropods, nematodes, oligochaeta) for which our knowledge of function and diversity remains very limited. This is related to the small size of the soilborne organisms, their diversity, the difficulty of accessing them, and to the great heterogeneity of their habitats at different scale levels. However, recent progresses in the molecular characterization of the biodiversity raises stimulating prospects to explore its complexity and better understand its functioning. Soil microorganisms, the central drivers of terrestrial Antarctic ecosystems, are being confronted with increasing temperatures as parts of the continent experience considerable warming. Here we determined short-term temperature dependencies of Antarctic soil bacterial community growth rates, using the leucine incorporation technique, in order to predict future changes in temperature sensitivity of resident soil bacterial communities. Contd. Effect of.microorganism Kheyrodin and Ghazvinian, 2012 In this study soil samples were collected along a climate gradient consisting of locations on the central Iran in Semnan city. The result demonstrated that the bacterial communities were adapted to the mean annual temperature of their environment, as shown by a significant correlation between the mean annual soil temperature and the minimum temperature for bacterial growth (Tmin). Every 1 1C rise in soil temperature was estimated to increase Tmin by 0.24–0.38 1C. The optimum temperature for bacterial growth varied less and did not have as clear a relationship with soil temperature. Temperature sensitivity, indicated by Q10 values, increased with mean annual soil temperature, suggesting that bacterial communities from colder regions were less temperature sensitive than those from the warmer regions.
Exploring Knowledge Sharing Practices for Raising Security Awareness

This study aims to explore the types of information can be effectively communicated in three knowledgesharing methods and their impact on employees’ security practice. On one end, guarding the organisation’s information system against cyber-attacks is critical and improving users’ knowledge and skills is a common approach to any security program. On the other end, organisations lack a clear understanding in determining what types of security information should be delivered through various methods of communication to be effective in boosting users’ knowledge and compliance behaviour. The study employed a qualitative method using semi-structured interviews with business users in Vietnam. The initial findings indicate a single method of knowledge and skill development is not sufficient to assist users to deal with complex and constant changing security needs. It is necessary to further experiment methods of encouraging formal and peer knowledge sharing that can support individual effort in complying with security policies.
VISUAL ANALYSIS FOR EVALUATING MYOCARDIAL PERFUSION IN CORONARY ARTERY DISEASE

© 2008 Elsevier. All rights reserved. Received: Jul 30, 2008 Accepted: Oct 27, 2008 Address correspondence and reprint requests to: Dr Jung-Chou Wu, Division of Cardiology, Department of Internal Medicine, Pingtung Christian Hospital, 60 Ta-Lian Road, Pingtung 900, Taiwan. E-mail: wujcdd@ms10.hinet. net COMPARISON OF AUTOMATED 4D-MSPECT AND VISUAL ANALYSIS FOR EVALUATING MYOCARDIAL PERFUSION IN CORONARY ARTERY DISEASE
Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy Dovepress

php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms (https://www.dovepress.com/terms.php). Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2019:12 149–159 Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy Dovepress
Improvement of antimicrobial metabolites by Saccharothrix flava VSM-3 using full factorial design and chemotype analysis

Ushakiranmayi Managamuri1, Muvva Vijayalakshmi1*, Venkata Siva Rama Rama Krishna Ganduri2, Satish Babu Rajulapati3, Sudhakar Poda4 1Department of Botany and Microbiology, Acharya Nagarjuna University, Guntur, India. 2Department of Biotechnology, Koneru Lakshmaiah Education Foundation, Vaddeswaram, India. 3Department of Biotechnology, National Institute of Technology, Warangal, India. 4Department of Biotechnology, Acharya Nagarjuna University, Guntur, India.
Semi-Supervised Unconstrained Action Unit Detection via Latent Feature Domain.

Facial action unit (AU) detection in the wild is a challenging problem, due to the unconstrained variability in facial appearances and the lack of accurate AU annotations. Most existing methods either depend on impractical labor-intensive labeling by experts, or inaccurate pseudo labels. In this paper, we propose an end-to-end semi-supervised unconstrained AU detection framework, which transfers accurate AU labels from a constrained source domain to an unconstrained target domain by exploiting accurate labels of AU-related facial landmarks. Specifically, we map a source image with AU label and a target image without AU label into a latent feature domain by combining source landmark-related feature with target landmark-free feature. Due to the combination of source AU-related information and target AU-free information, the latent feature domain with the transferred source AU label can be learned by maximizing the target-domain AU detection performance. Moreover, to disentangle landmark-related and landmark-free features, we introduce a novel landmark adversarial loss which can solve the multi-player minimax game in adversarial learning. Our framework can also be naturally extended for use with target-domain pseudo AU labels. Extensive experiments show that our method soundly outperforms the baselines, upper-bounds and state-of-the-art approaches on the challenging BP4D, GFT and EmotioNet benchmarks. The code for our method is available at https://github.com/ZhiwenShao/ADLD.
Visrepo: A Centralized and Open Source Visualization Repository and Knowledgebase

Through this paper, we propose a visualization repository Visrepo. Visrepo is an effort to collect and organize information about different visualization types from variant sources into a one central knowledgebase. This knowledgebase aims to provide an open source and publicly accessible online environment that: 1) provides the visualization community with a curated central database of different visualization types, 2) that can be reused and edited to fulfill the diverse user requirements, 3) fosters visualization literacy by providing knowledge about different visualization types referenced from scholarly articles and 4) enables long term visualization data curation for visualization theoretical research.
A simplified Fornberg-like method for the conformal mapping of multiply connected regions—Comparisons and crowding

We present a new Fornberg-like method for the numerical conformal mapping of multiply connected regions exterior to circles to multiply connected regions exterior to smooth curves. The method is based on new, symmetric conditions for analytic extension of functions given on circular boundaries. We also briefly discuss a similar method due to Wegmann and compare some computations with both methods. Some examples of regions which exhibit crowding of the circles are also presented. © 2006 Elsevier B.V. All rights reserved. MSC: 30C30
AN OPTIMAL APPROACH FOR VELOCITY INTERPOLATION IN MULTILEVEL VOF METHOD

Abstract. The use of mesh refinement techniques is becoming more and more popular in computational fluid dynamics, from multilevel approaches to adaptive mesh refinement. In particular, direct numerical simulations of two-phase flow have seen recently the introduction of a finer grid for interface representation. In general, the mesh used for surface tension calculations requires higher resolution than the grid where the conservation equations are discretized and the introduction of these auxiliary grids overcomes some well-known limitations of Volume-of-Fluid (VOF) and Level Set methods. In particular for VOF methods, the interface discontinuity at the cell boundary can cause the deformation of the interface shape at low resolution even for simple translations and solid-body rotations. In fact different interface lines interact with each other in the reconstruction step at a distance of a couple of grid spacings, causing distortion and eventually numerical break-up of the interface. The methodology we present provides a smoother description of the interface and its geometrical properties which are necessary for an accurate capillary force evaluation. The use of different grids for Navier-Stokes equations and interface representation requires the projection of the velocity field from the coarse to the higher resolution grid. This procedure is not trivial, especially for incompressible flows where the divergence-free constraint must be satisfied on both grids. In this paper we present a new method to estimate the velocity field on the fine mesh based on an optimal approach. This algorithm allows us to satisfy the divergence-free constraint in every cell of the fine grid in twoand three-dimensional geometry. This is achieved by a constrained minimization of an objective functional. The proposed functional is the integral of the square of the error between the computed and the linear interpolation velocity field. The minimization is subject to the divergence-free constraint which therefore must be always satisfied. In this way, the projected velocity field is divergence-free and the interface advection does not generate unrealistic situations that could lead to an unphysical behavior. In the last part of the paper we present some results obtained with the above method in two-phase flow simulations in order to assess its reliability and robustness.
Clinical report on protocol B-NHL 2001 for childhood B-non Hodgkin's lymphoma

Objective To analyze the efficacy of protocol B-NHL2001 for B cell non-Hodgkin's lymphoma(B-NHL) and anaplastic large cell lymphoma(ALCL). Methods Depending on the reports from developed country and the results of our former protocol NHL-CCCG-97,the protocol B-NHL 2001 revised the eligibility,grouping criteria,intensity of chemotherapy and time of treatment.Patients were divided into low,middle and high risk groups(R1,R2,R3) based on staging and the level of lactate dehydrogenase(LDH),and given 3,5,and 6 courses of chemotherapy respectively.All the patients from 2001 to June 2007 were enrolled.The software of SPSS 11.0 was used and the event free survival was generated by Kaplan-Meier.Results There were 45 patients in total,35 males and 10 females.The average age was 7.1 years(ranged from 10 months to 15.5 years),medium age was 6.3 years.Two patients were in stage Ⅰ,17 in stageⅡ,18 in stageⅢ and 8 in stageⅣ. The original tumor was found in abdomen for 23 patients,nose-pharynges for 7,periephel lymph-nodes for 7,cutaneous for 1,mediastinum for 1,bone for 2,mumps for 2,chest wall for 1 and extensive infiltration in chest and abdomen for 1.They were pathologically sub-classified as Burkitt's for 14 cases,large B cell for 13,anaplastic large cell for 3 and B-NHL(non-lymphoblastic,no further sub-classification) for 15.Two patients were allocated into low risk group(R1),14 into middle risk group(R2) and 29 into high risk group(R3). Three were ruled off the analysis because of abandoning treatment by parents after 1 course therapy without progressive disease(1 of stage Ⅰ,2 of stage Ⅲ). Forty-one of 45 patients reached complete response(CR) after 2 courses of chemotherapy.Another 3 received second look surgery because of residual disease after 3 courses therapy,2 of them were proved CR(no tumor cells in residual mass) by pathology,1 with alive tumor cells.In total,43 of 45 reached CR(95.5%),one of stage Ⅲ and one of stage Ⅳ never reached CR.To Dec 2007,40 of them kept in CR(88.9%) with 6 to 77 months follow-up,average 26.9 months,medium 19 months.Three cases relapsed at original place,bone marrow and in cranial(2 of stage Ⅲ and 1 of stage Ⅳ) which occurred in 5,6 and 8 months.The estimated 5-year event free survival(EFS)was 88.3%. Conclusions The estimated 5-year event free survival indicated that B-NHL 2001 was reasonable for both B-NHL and ALCL and worth to enroll more patients.