Miracle-dz/UniFAR-FTUs huggingface dataset:
Estimação de componentes de co-variância para pesos corporais do nascimento aos 365 dias de idade de bovinos Guzerá empregando-se modelos de regressão aleatória

A total of 19,770 body weight records of Guzera cattle, measured from birth to 365 days of age and supplied by the Brazilian Zebu Breeders Association, was analyzed with the following objectives of: 1) to compare different residual variances through step functions with 1, 18, 28 and 53 classes and through variance functions with orders ranging from two to five using ordinary polynomials and 2) to estimate covariance functions considering different orders for direct additive genetic effects, animal permanent environmental and maternal permanent environmental effects, using random regression models. The random effects included were modeled by regression on Legendre Polynomials with orders ranging from linear to quartic. The models were compared through the likelihood ratio test, Akaike's information criterion and the Schwarz's Bayesian information criterion. The model with 18 heterogeneous classes was the one that best fitted the residual variances, according to the statistical tests; however, the model with variance function of 5th order also showed to be appropriate. The direct heritability estimates were higher than those found in literature, ranging from 0.04 to 0.53, showing similar trends when compared to those estimated using univariate models. Selection on body weight in any age should improve the body weight in all ages in the studied interval.
ANALISIS PENYUSUNAN LAPORAN KEUANGAN BERDASARKAN PERNYATAAN STANDAR AKUNTANSI KEUANGAN (PSAK) NO. 45 (Studi Kasus : Yayasan Pesantren Al-Husna)

Tujuan penelitian ini adalah menyajikan laporan keuangan Yayasan Pesantren Al-Husna berdasarkan Pernyataan Standar Akuntansi Keuangan (PSAK) No. 45. Dari penelitian ini diketahui bahwa penyusunan laporan keuangan Yayasan Pesantren Al-Husna belum memadai . hal ini dapat dilihat dari laporan keuangan yayasan yang hanya berisakan laporan penerimaan dan pengeluaran yayasan saja, padahal menurut Pernyataan Standar Akuntansi Keuangan (PSAK) No. 45 organisasi nirlaba seperti Yayasan dapat menghasilkan laporan keuanga yang terdiri dari laporan posisi keuangan, laporan aktivitas, laporan arus kas, dan catatan atas laporan keuangan. Teknik analisis data menggunakan analisis deskriptif kualitataif yang berdasarkan pada langkah-langkah laporan keuangan. Dikarenakan yayasan belum membuat laporan keuangan yang sesuai dengan PSAK No. 45, maka penulis menyarankan dan membuat contoh pembuatan laporan keuangan yang sesuai dengan PSAK No. 45. Hasil penelitian ini, laporan keuangan Yayasan Pesantren Al-Husna berdasarkan pedoman PSAK No. 45 sesuai dengan informasi yang didapat.
Who should be responsible for our common well-being? A Gross National Happiness approach to promoting a responsive and sustainable Business Community

The roles and responsibilities of the business community to the society are underexplored and least understood both by the business community as well as by the society in general. In the absence of any guideline on the societal responsibilities of the business community in Bhutan, an intellectual gap possibly exists between the ideology of Gross National Happiness and the roles of the business community. Thus, this review explores the tangible societal responsibilities of the business community. It also discuses the long-established arguments on the roles of business to society beyond profit making and maximizing its financial well-being. Using key words such as the business community, well-being, social responsibilities, Buddhist economics, western economics, and sustainable business, 114 articles were retrieved from the web-based resources. The data generated thus were analysed using the constant comparison analysis of QUAL approach. The finding indicates that the societal responsibility of the business community is an oxymoron conceptually. The paper also addresses the principles of Gross National Happiness as an approach to promoting a responsive and sustainable business community. However, an in-depth research is necessary to understand the roles and responsibilities of the business community in the context of Gross National Happiness.
Espécies novas de epanthidium moure e de austrostelis michener & griswold (hymenoptera, apidae, megachilinae)

Epanthidium araranguense sp. nov. from Santa Catarina, Epanthidium chapadense sp. nov. from Mato Grosso do Sul, Epanthidium flavoclypeatum sp. nov. from Minas Gerais, Austrostelis amapaensis sp. nov. from Amapa, Austrostelis santaterezae sp. nov. from Espirito Santo and Austrostelis silveirai sp. nov. from Minas Gerais are described and illustrated. A key to identify the species of Austrostelis is presented.
Screening of topical sterilants for shoot apex culture of Acacia mearnsii

The surface sterilisation procedure is of integral importance to any micropropagation technique. This process should do the least amount of plant damage, whilst reducing microbial contamination to an acceptable level. The objective of this research was to investigate alternative sterilisation agents to the dangerous chemical mercuric chloride (HgCl2), and to determine the effect of sterilant exposure time on shoot apex culture of Acacia mearnsii. Explants were cultured on MS medium supplemented with 2.0 mg l–1 BA and monitored for 21 d for signs of contamination and shooting. Household bleach (NaOCl), diluted 1:3 in water, resulted in decontaminated explant levels not significantly different to the 0.2% HgCl2 treatment and resulted in shoot development levels significantly higher than the 0.2% HgCl2 treatment. There was no significant effect of sterilant exposure time on decontaminated explant levels, whilst the shortest exposure time resulted in significantly higher shooting levels than the other two time periods tested.
Stocking Fingerling Largemouth Bass to Alter Genetic Composition: Efficacy and Efficiency of Three Stocking Rates

Abstract The Texas Parks and Wildlife Department (TPWD) has stocked Florida largemouth bass Micropterus salmoides floridanus to alter the genetic composition of largemouth bass populations since 1972. Because most stocked fingerling largemouth bass remain within 1 km of their stocking site, TPWD's current stocking procedures and standard stocking rates of 10–41 fingerlings/surface ha typically yield 10,000–100,000 fish/stocked site (i.e., 2 km of shoreline). The efficacy and efficiency of these stocking rates are unknown. We determined the percent contribution of stocked fingerling (28–66-mm) Florida largemouth bass to the age-0 cohort in Toledo Bend Reservoir, Texas, when the fish were stocked at three rates (1,000, 10,000, and 100,000 fish/site) as well as the associated production and stocking costs. Three weeks after stocking, stocked fish increased the proportion of largemouth bass that were homozygous for alleles characteristic of Florida largemouth bass at all treatments (P < 0.013). Thus, stocking.
Chromosomal evolution in the Diplodactylinae (Gekkonidae: Reptilia). I: Evolutionary relationships and patterns of change

A chromosomal analysis of 47 species of diplodactyline gekkos indicates that these are a monophyletic assemblage derived from a 2n = 38 acrocentric ancestral karyotype. Four major clades are present, the first possessing the ancestral karyotype. The remainder are defined by the possession of a series of shared derived chromosomal rearrangements, or by the type of chromosome change. The first of these derived clades includes the subgenus Strophurus, which has five fixed, presumed pericentric inversion differences. The second includes members of the D. vittatus species group. Here, a number of chromosome fusions have been established which appear to have been associated with speciation. The third derived clade is distinguished by 19 fixed, presumed pericentric inversions, and includes the genera, Oedura, Rhacodactylus, Bavayia, Pseudothecadactylus, Carphodactylus and Hoplodactylus. It is argued that the 2n=38 acrocentric karyotype common to many of the species is the ancestral karyomorph, and the modifications of this format have been achieved by both chromosome fusion and pericentric inversion. The decision that this is the ancestral karyomorph was based on its dominance in extant species; the fact that similar karyotypes are present in other gekkonid subfamilies (effective out-groups), that 2n =38 all acrocentric ancestral karyotypes are also found in some other lizard families, and that such a diversity of rearrangements was established, provide arguments against any other viable ancestral format. Two discrete modes of chromosomal repatterning are found in the Diplodactylinae: the fixation of presumptive multiple pericentric inversions, producing a karyomorph which characterises large groups of species; and the fixation of fusion or presumptive inversion differences which distinguish individual species or chromosome races. The latter appear to have been associated with speciation. It is clear that in certain groups, such as the Strophurus species group (the members of which all share a derived karyomorph defined by the presence of five inverted chromosomes), speciation has proceeded without gross chromosomal rearrangements.
Factors for high frequency plant regeneration in tissue cultures of Indian mustard (Brassica juncea L.)

An efficient system for high frequency plant regeneration was established through investigating various factors such as plant growth regulator combinations, explant types and ages, and addition of influenced on shoot regeneration in Brassica juncea L. cv. BARI sarisha-10. Murashige and Skoog (MS) medium supplemented with 0.1 mg/L NAA (1-naphthaleneacetic acid) and 1 mg/L BA (6-benzyladenine) showed the maximum shoot regeneration frequency (56.67%) among the different combinations of NAA and BA. Explant type, explant age, and addition of also significantly affected shoot regeneration. Of the four type of explants (cotyledon, hypocotyl, root, and leaf explants)- cotyledon explants produced the highest shoot regeneration frequency and hypocotyls explants produced the highest number of shoots per explant, whereas root explants did not produce any shoot. The cotyledonary explants from Four-day-old seedlings showed the maximum shoot regeneration frequency and number of shoots per explant. Shoot regeneration frequency increased significantly by adding to the medium. Two mg/L appeared to be the best for shoot regeneration with the highest shoot regeneration frequency (86.67%) and number of shoots per explant (7.5 shoots). Considerable variation in shoot regeneration from cotyledonay explants was observed within the B. juncea L. genotypes. The shoot regeneration frequency ranged from 47.78% for cv. Shambol to 91.11% for cv. Rai-5. In terms of the number of shoots produced per explant, B. juncea L. cv. Daulot showed the maximum efficiency. MS medium supplemented with 0.1 mg/L NAA showed the highest frequency of rooting. The regenerated plantlets were transferred to pot soil and grown to maturity in the greenhouse. All plants were fertile and morphologically identical with the source plants.
The biology of Dasineura dielsi Rübsaamen (Diptera: Cecidomyiidae) in relation to the biological control of Acacia cyclops (Mimosaceae) in South Africa

Acacia cyclops is an invasive Australian tree in South Africa and a target for biological control using seed-reducing agents. In southern Australia, two gall-forming Cecidomyiidae, Dasineura dielsi (Small Fluted Galler) and Asphondylia sp. , develop on the flowers and seeds of A. cyclops, respectively. The larvae of D. dielsi form woody fluted galls on the ovaries of flowers and prevent the development of fruit. Immature Asphondylia sp. develop in the loculi of green fruit and destroy developing seeds. Dasineura dielsi was selected as a biological control candidate for A. cyclops in South Africa and was approved for official release after host specificity evaluation and consideration of potential conflicts of interest. Dasineura dielsi naturalised in South Africa in 2001 and after 3 years dispersed up to 450 km from a single population at Stellenbosch, Western Cape. At sites where D. dielsi has been present longest, high gall densities occur on A. cyclops during the peak flower season in summer. Four hymenopterans, ? Synopeas sp. , Mesopolobus sp. , Torymus sp. and an unidentified Platygastridae, were reared from D. dielsi galls and are suspected parasitoids of the cecidomyiid, with incidence levels less than 10%. Monitoring is required to evaluate trends in the population status of D. dielsi, its parasitoids and seed production of A. cyclops. Importantly, field monitoring should determine the extent and nature of possible competitive interactions between D. dielsi and an introduced seed-feeding weevil, Melanterius servulus.
Predictive values of blood tests to diagnose LTBI have not been established in children

For almost a century, the only test available to diagnose latent tuberculosis infection (LTBI) has been the tuberculin skin test (TST). This test involves the intradermal injection of an array of proteins called purified protein derivative (PPD), then measurement of the induration of the surrounding skin caused by a delayed-type hypersensitivity reaction. Although this test has been very useful, especially in clinical situations when the risk of tuberculosis disease or LTBI is high, it is fraught with imprecision and inconsistency, leading to problems with both the sensitivity and specificity of the test. In the past four years, two blood tests for the diagnosis of tuberculosis infection have been approved by the Food and Drug Administration (FDA) for use in the United States. When persons infected with Mycobacterium tuberculosis develop a delayed-type hypersensitivity cellular immune response to the organism, their lymphocytes produce interferon-gamma. These tests measure the ability of the patient’s lymphocytes to produce interferon-gamma after the lymphocytes have been exposed in vitro to proteins that are found in M. tuberculosis. As with the TST, these tests, called interferon-gamma release assays (IGRAs), cannot distinguish between LTBI and tuberculosis disease. The first IGRA approved for use in the United States (August 2005) was QuantiFERON (Cellestis Ltd., Carnegie, Victoria, Australia). The test measures the total amount of interferongamma produced in vitro by lymphocytes in the patient’s blood. The threshold amount (differentiating between a positive and negative result) was determined from studies in adult patients with and without tuberculosis disease (TB). Each test is run with a positive and negative control. Several modifications have been made to the test, and the latest version, QuantiFERON-TB Gold In-tube, uses three antigens: early secretory antigen target-6 (ESAT-6), culture filter protein-10 (CFP10) and tb7.7 (p4). The second IGRA, approved by the FDA in August 2008, is the T-SPOT.TB test (Oxford Immunotec, Oxfordshire, U.K.). This test stimulates the patient’s lymphocytes in vitro with ESAT-6 and CFP-10, and counts the number of lymphocytes that produce interferon-gamma. Positive and negative controls are always included.
A MULTIPHASE MULTISCALE MODEL FOR NUTRIENT-LIMITED TISSUE GROWTH, PART II: A SIMPLIFIED DESCRIPTION

In this paper, we revisit our previous work in which we derive an effective macroscale description suitable to describe the growth of biological tissue within a porous tissue-engineering scaffold. The underlying tissue dynamics is described as a multiphase mixture, thereby naturally accommodating features such as interstitial growth and active cell motion. Via a linearization of the underlying multiphase model (whose nonlinearity poses a significant challenge for such analyses), we obtain, by means of multiple-scale homogenization, a simplified macroscale model that nevertheless retains explicit dependence on both the microscale scaffold structure and the tissue dynamics, via so-called unit-cell problems that provide permeability tensors to parameterize the macroscale description. In our previous work, the cell problems retain macroscale dependence, posing significant challenges for computational implementation of the eventual macroscopic model; here, we obtain a decoupled system whereby the quasi-steady cell problems may be solved separately from the macroscale description. Moreover, we indicate how the formulation is influenced by a set of alternative microscale boundary conditions.
A general surface reconstruction method for post-processing of topology optimisation results

In this work, a new semi-automatic surface reconstruction procedure is proposed. The main goal of the method is to reconstruct the boundary surface of a triangulation obtained as a result of a topology optimisation calculation. The reconstruction problem is articulated in two main phases: tessellation mapping and surface fitting. The first phase consists of retrieving a suitable map of the triangulation representing the boundary of the optimised topology. To this purpose, a segmentation of the original triangulation is performed and sub-domains (i.e. patches) are identified by means of a semi-automatic strategy. Then, a shape preserving parametrisation algorithm [1] is used on each patch in order to carry out the mapping and to preserve the real 3D shape of the boundary. The second phase deals with an original approach to the surface fitting problem: the problem is stated as a Constrained Non-Linear Programming Problem (CNLPP) by introducing a constraint on the maximum value of the Gaussian curvature of the boundary surface. In this study, the surface fitting problem is solved in the framework of Non-Uniform Rational Basis Splines (NURBS) surfaces. The main idea is to keep all the parameters defining the NURBS surface as design variables in order to state the surface fitting problem in the most general sense. Nevertheless, this fact implies two consequences of paramount importance, constituting just as many difficulties in solving the related CNLPP. Firstly, when the surface fitting problem is formulated by including the number of control points and the degrees of the basis functions among the unknowns, the overall number of design variables for the problem at hand is not fixed a-priori: hence, the resulting CNLPP is defined over a search space of variable dimension. Secondly, the numerical strategy chosen to face such a problem must be able to handle design variables of different nature and to optimise, at the same time, the dimension of the design domain as well as the value of each constitutive parameter of the NURBS surface. In order to overcome the two aforementioned issues, the surface fitting phase is composed of two optimisation steps. Firstly, the ERASMUS (EvolutionaRy Algorithm for optimiSation of ModUlar Systems) tool [2] optimises both the value and the number of design variables by means of a two-level Darwinian strategy, allowing the simultaneous evolution of individuals and species. Secondly, the optimum solution provided by ERASMUS constitutes the initial guess for the local gradient-based optimization, which aims at improving the accuracy of the fitting surface. The proposed method coupled with the NURBS based SIMP algorithm [3], represents a valid solution for the semi-automatic post-processing of complex 3D shapes resulting from topology optimisation.
Structural basis and energy landscape of apigenin-induced cancer cell apoptosis mechanism in PI3K/Akt pathway

This study attempted to elucidate how apigenin (AGI) interferes with the PI3K/Akt pathway to fulfill its anti-tumour activity by anchoring on the ATP-binding pocket of PI3K and PDK1. The structural basis and energetic property of AGI and ATP binding to human PDK1 and PI3K isoforms α, β, γ and δ were investigated in detail with homology modelling and molecular docking. Free binding energy calculations and molecular dynamics simulations revealed that AGI can cause less conformational entropy loss than ATP upon the binding and possess the same level of binding stability with that of ATP. Combining ADMET prediction, AGI was evaluated as a strong ATP-competitive inhibitor with good pharmacokinetics profile.
Determination of L-Cysteine with L-Methionine γ-Lyase

Several procedures have been presented for the determi- nation of L-cysteine. Some of them are sensitive, but indistinguishable between L-cysteine and other thiol compounds such as methanethiol and ethanethiol (e.g., the spectrophotometric methods with 5,5'-dithiobis(2- nitrobenzoic acid)1' and 7V-ethylmaleimide2)). We have purified L-methionine y-lyase (EC 4.4.1.1 1) to homogeneity from Pseudomonas putida (=Ps. ovalis) to elucidate The enzyme, 5'-phosphate as a co factor, catalyzes a,y-elimination of L-methionine and its derivatives, and also, a,/? -elimina-tion [2] of L-cysteine and its derivatives as follows.
Survival and retention of Eschenchia coli O157:H7 and Campylobacter in contrasting soils from the Toenepi catchment

Abstract The effect of soil type on transfer of zoonotic bacteria to rural streams was investigated using intact cores and turfs of Topehaehae gley soil and Kereone sandy loam. Simulated farm dairy effluent, containing laboratory grown Escherichia coli O157:H7 and Campylobacter, was added to cores and turfs that were stored at 10°C. Bacterial survival was measured in cores over 28 days. Simulated rainfall was applied at 25 and 50 mm h‐1 to allow measurement of bacterial transfer to drainage (over 28 days) or surface runoff (at 7 days). Although both bacteria survived for 28 days, Campylobacter declined faster than E. coli O157:H7 with no differences identified for soil type. For Topehaehae soil there was little change in retention of E. coli O157:H7 over the 28 days for both rainfall rates, but there was an increase in retention over time for Kereone. In contrast there was an increase in retention of Campylobacter in both soils at either of the rainfall rates. When surface runoff was measured, less than 1% of each of the applied bacteria was recovered from either soil irrespective of rainfall rate. These findings suggest that rainfall will transfer faecal bacteria from gley soils bordering a stream to the water for at least 28 days after deposition.
Restoring North America's Birds: Lessons from Landscape Ecology

This volume draws on research on bird species and their habitats to explain how basic principles of bird ecology and landscape ecology can help us create scientifically sound plans for protecting and restoring the rich diversity of North American birds. This edition includes an afterword that reviews literature that has appeared since the first edition was completed in 1999. This new material - on such key issues as the importance of preserving large expanses of natural habitat, the importance of maintaining early successional habitats, and the habitat requirements of neotropical migrants - shows how the research on landscape ecology of birds has shaped conservation policy more rapidly than most would have predicted.