Miracle-dz/UniFAR-FTUs huggingface dataset:
The Decay Data Evaluation Project (DDEP) and the JEFF-3.3 radioactive decay data library: Combining international collaborative efforts on evaluated decay data

The Decay Data Evaluation Project (DDEP), is an international collaboration of decay data evaluators formed with groups from France, Germany, USA, China, Romania, Russia, Spain and the UK, mainly from the metrology community. DDEP members have evaluated over 220 radionuclides, following an agreed upon methodology, including a peer review. Evaluations include all relevant parameters relating to the nuclear decay and the associated atomic processes. An important output of these evaluations are recommendations for new measurements, which can serve as a basis for future measurement programmes. Recently evaluated radionuclides include: 18 F, 59 Fe, 82 Rb, 82 Sr, 88 Y, 90 Y, 89 Zr, 94m Tc, 109 Cd, 133 Ba, 140 Ba, 140 La, 151 Sm and 169 Er. The DDEP recommended data have recently been incorporated into the JEFF-3.3 Radioactive Decay Data Library. Other sources of nuclear data include 900 or so radionuclides converted from the Evaluated Nuclear Structure Data File (ENSDF), 500 from two UK libraries (UKPADD6.12 and UKHEDD2.6), the IAEA Actinide Decay Data Library, with the remainder converted from the NUBASE evaluation of nuclear properties. Mean decay energies for a number of radionuclides determined from total absorption gamma-ray spectroscopy (TAGS) have also been included, as well as more recent European results from TAGS measurements performed at the University of Jyvaskyla by groups from the University of Valencia, Spain and SUBATECH, the University of Nantes, France. The current status of the DDEP collaboration and the JEFF Radioactive Decay Data Library will be presented.
BLOOMING ASTONISHINGLY OF BIOINFORMATICS AND ITS APPLICATIONS

: Bioinformatics is the discipline that uses computers to store, retrieve, manipulate and distribute information related to biological macromolecules such as RNA, DNA and proteins. It is broad term covering the use of computer algorithms to analyze biological data. For theoretical analysis and therapy design to be carried out effectively, a range of tools and resources need to be made available in both experimental and computational aspects. The Bioinformatics websites were useful resources for determining whether a specific genomic region is disrupted frequently in a particular disease or malignancy and for finding chromosomal cell lines and reagents for regional mapping, for e.g., NCBI. This helps in developing integrated data bases over the internet. This also helps in understanding function of gene and also genome. Various www servers and Internet are quiet potent and playing a dynamic role in the Bioinformatics field. It is destinated to change the face of biomedicine.
Isolation and Characterization of phyC Mutants in Arabidopsis Reveals Complex Crosstalk between Phytochrome Signaling Pathways

Studies with mutants in four members of the five-membered Arabidopsis phytochrome (phy) family (phyA, phyB, phyD, and phyE) have revealed differential photosensory and/or physiological functions among them, but identification of a phyC mutant has proven elusive. We now report the isolation of multiple phyC mutant alleles using reverse-genetics strategies. Molecular analysis shows that these mutants have undetectable levels of phyC protein, suggesting that they are null for the photoreceptor. phyC mutant seedlings were indistinguishable from wild-type seedlings under constant far-red light (FRc), and phyC deficiency had no effect in the phyA mutant background under FRc, suggesting that phyC does not participate in the control of seedling deetiolation under FRc. However, when grown under constant red light (Rc), phyC seedlings exhibited a partial loss of sensitivity, observable as longer hypocotyls and smaller cotyledons than those seen in the wild type. Although less severe, this phenotype resembles the effect of phyB mutations on photoresponsiveness, indicating that both photoreceptors function in regulating seedling deetiolation in response to Rc. On the other hand, phyB phyC double mutants did not show any apparent decrease in sensitivity to Rc compared with phyB seedlings, indicating that the phyC mutation in the phyB-deficient background does not have an additive effect. These results suggest that phyB is necessary for phyC function. This functional dependence correlates with constitutively lower levels of phyC observed in the phyB mutant compared with the wild type, a decrease that seems to be regulated post-transcriptionally. phyC mutants flowered early when grown in short-day photoperiods, indicating that phyC plays a role in the perception of daylength. phyB phyC double mutant plants flowered similarly to phyB plants, indicating that in the phyB background, phyC deficiency does not further accelerate flowering. Under long-day photoperiods, phyA phyC double mutant plants flowered later than phyA plants, suggesting that phyC is able to promote flowering in the absence of phyA. Together, these results suggest that phyC is involved in photomorphogenesis throughout the life cycle of the plant, with a photosensory specificity similar to that of phyB/D/E and with a complex pattern of differential crosstalk with phyA and phyB in the photoregulation of multiple developmental processes. of the total Rc-imposed repression of ATHB-2 in Col-0. These results indicate that phyC may participate, albeit marginally, in the repression of ATHB-2 expression driven by Rc during seedling deetiolation.
Study of tracking and software performance of the ATLAS Inner Tracker in staged-installation scenarios at the High-luminosity LHC

The current baseline construction schedule of the Pixel detector of the ATLAS Phase-2 Inner Tracker (ITk) is in tension with its foreseen installation date during Long Shutdown (LS) 3. Different staged-installation scenarios are being discussed that could help advancing the construction schedule. This would provide enough time contingency to ensure completion of the detector before the start of the run period. In the considered scenarios, only part of the nominal ITk Pixel detector would be installed during LS3 and be present for the Run-4 data-taking, while the rest of the detector would be installed during LS4. This note presents a study of the implications of the proposed staging scenarios on track reconstruction, physics and technical performance. Tracking and flavour-tagging performance are more severely impacted when taking into account detector defects, while an increase in computing power beyond 40% is needed to guarantee reasonable tracking performance even in the absence of defects, with major implications for the tracking reconstruction in trigger.
Proaleurain Vacuolar Targeting 1s Mediated by Short Contiguous Peptide lnteractions

Targeting of soluble proteins to the plant vacuole is mediated by determinants that reside in the polypeptide. We identified the vacuolar targeting determinant of aleurain, a plant vacuolar thiol protease, by incorporating different sequences from proaleurain into the secreted thiol protease, proendoproteinase B (proEP-B), and vice versa. The targeting fates of the chimeric proteins were analyzed by transient expression in electroporated tobacco protoplasts. The targeting determinant SSSSFADSNPIR is positioned at the N terminus of the aleurain propeptide, and its substitution into the propeptide of EP-B caused vacuolar targeting of the resulting chimeric protein. This determinant can be divided into two smaller determinants, SSSSFADS and SNPIR, each of which is sufficient to target proEP-8 chimeras to the vacuole, but with lower efficiency. These smaller determinants interact in a positive manner because the combined determinant SSSSFADSNPIR targeted proEP-B with an efficiency greater than each of the smaller determinants alone. Accordingly, the efficiency of aleurain targeting was decreased when either of the smaller determinants was disrupted by replacement with similarly positioned proEP-B sequences. Further experiments on proaleurain identified an additional determinant, VTDRAAST, adjacent to the SSSSFADSNPIR determinant that is also necessary for efficient vacuolar targeting. Our results provide evidence that efficient vacuolar targeting of this thiol protease in plant cells is mediated by the combined action of smaller contiguous determinants; two of these alone are sufficient for vacuolar targeting.
A novel locality-based clustering method of undirected, unweighted networks

In this paper a new locality-based clustering algorithm is introduced for partitioning undirected, unweighted graphs. This algorithm applies a new similarity measure based on the common neighbors of the vertices. Results of the suggested algorithm are compared to the generated clusters of the Girvan-Newman method as well as the running time is also measured on different data sets. The efficiency and the advantages of the proposed method, as well as our results are also presented in this paper through some application examples
Glial cell line-derived neurotrophic factor increases intracellular calcium concentration: role of calcium/calmodulin in the activation of the phosphatidylinositol 3-kinase pathway

Acknowledgements: This work has been supported by grants FIS (PI021357) from Ministerio de Sanidad y Consumo to R.M.S.; SAF2000-0164-C02-01 from Ministerio de Ciencia y Tecnología, QLG3-CT-1999-00602 from the European Commission, SGR and Distinció Joves Investigadors from Generalitat de Catalunya to J.X. C; and BFI2001-1565 from the Ministerio de Ciencia y Tecnología; G03/167 from the Ministerio de Sanidad; PAI-02-031 from the Consejería de Ciencia y Tecnología, JCCM
Low‐complexity transmit antenna selection algorithm exploiting null space in spatial multiplexing UWB MIMO systems

In this paper, a new transmit antenna selection algorithm for spatial multiplexing ultra‐wideband multiple‐input multiple‐output systems is proposed. It utilizes the null space of the channel matrix spatially and temporally combined for available transmit antennas. A selection strategy is used to successively find and remove the transmit antennas having the largest contribution to the null space. Its error performance is shown to be close to that of the optimal antenna selection algorithm with low complexity. © 2017 Institute of Electrical Engineers of Japan. Published by John Wiley & Sons, Inc.
Structural And Electronic Properties Of III- Nitride Semiconductor Alloys: A First Principle Study

Semiconductors are the most investigated today and are the basic building blocks of emitters and receivers in optoelectronic devices. Group-III nitrides have tremendous applications in various industries dealing with optoelectronic devices [1-4]. There are huge number of semiconductor devices made by intermixing elements from III and V group of the periodic table. These compounds are used for LED/LD, fiber communication and solar cells. The compounds which are made from GaN are very significant in lighting systems. Silicon is the most commonly used material in ICs. In, P, and Al are also commonly used for the similar purposes with higher operational efficiency. The operational efficiency pertains to its higher electron mobility [5 -11]. Since these devices are efficient and operate with lower voltages, they are commonly used in space vehicles and satellites. A Laser made from InGaAsP emits radiation at 1.55 μm which is used for transferring streams of information in the form of digitally codes.
Chloroform 21 3 Toxicokinetics and Metabolism 3 . 1

MAK value (1999) 0.5 ml/m  2.5 mg/m Peak limitation (1983) II,1 Absorption through the skin (1999) H Sensitization – Carcinogenicity (1999) Category 4 Prenatal toxicity (1999) C Germ cell mutagenicity – BAT value – Synonyms trichloromethane Chemical name (CAS) trichloromethane CAS number 67-66-3 Structural formula CHCl3 Molecular weight 119.38 Melting point –63.5°C Boiling point 61.7°C Density at 20°C 1.48 g/cm Vapour pressure at 20°C 211 hPa 1 ml/m (ppm)  4.962 mg/m 1 mg/m  0.202 ml/m (ppm)
Valorization of Carbon Dioxide into Oxazolidinones from Aziridines

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Does Renal Denervation Inhibit Atherosclerosis in Humans?

Renal sympathetic nerve activity in hypertensive patients is increased [1]. Renal Denervation (RDN) may decrease blood pressure in humans by decreasing renal sympathetic nerve activity. This hypothesis was first tested by the proof-of-principle Symplicity HTN-1 trial (N=45) [2] which showed that RDN lowered office systolic blood pressure by 22 mm Hg at 6 months in patients complicated with resistant hypertension. Later, the randomised but not sham-controlled nor blinded Symplicity HTN-2 trial (N=106) confirmed the effectiveness of RDN in lowering blood pressure [3]. Subsequently, RDN has become a standard treatment option for patients with resistant hypertension in many countries. RDN was then regarded as the possible cure for resistant hypertension [4], and may significantly decrease the morbidity and mortality of cardiovascular diseases including myocardial infarction and stroke [5], diseases with atherosclerosis being a major underlying cause.
OPTH_A_299338 1201..1206

*These authors contributed equally to this work Purpose: To evaluate the prevalence of meibomian gland dysfunction (MGD) among ophthalmic healthcare workers. Setting: A tertiary ophthalmic center. Design: Prospective, observational study. Methods: Forty-four volunteer ophthalmologists and ophthalmic nurses were recruited. Information including demographics, contact lens wear, history of refractive surgery and symptom score based on Standardized Patient Evaluation of Eye Dryness (SPEED) II Questionnaire for Dry Eye Disease/Ocular Surface Disease were recorded. Lipid layer thickness (LLT), meibomian glands dropout and dilation grades, and proportion of partial blinking were evaluated using an ocular surface interferometer with dynamic meibomian imaging (LipiView, Johnson & Johnson). Based on the chance of MGD, meibomian gland dropout and dilation, selected subjects also underwent treatment with a thermal pulsation system (LipiFlow, Johnson & Johnson) in one or both eyes. Results: Eighty-eight eyes of 44 volunteers were evaluated during the study period. The mean LLT was 60.0nm. Twenty-seven (61.4%) subjects had a 90% or high chance of MGD and their mean lower lid meibomian gland dropout and dilation grades were 1.2 and 1.7, respectively. Twenty-eight eyes of 16 volunteers received treatment with the thermal pulsation system. Following treatment, the mean LLT improved from 50.3nm to 61.0nm (Wilcoxon’s signed rank test, p=0.001). Conclusion: Despite being more knowledgeable to MGD and more accessible to treatment, MGD is a highly prevalent condition among ophthalmic healthcare workers, with a 61.4% prevalence among the recruited subjects. This is similar to reported prevalence in Asian populations of up to 74.5%. Targeted therapy based on dynamic meibomian imaging is effective in improving both objective and subjective measures of MGD.
refugia-within-refugia during the Pleistocene Ice Age: genomic evidence from two newt

19 Part of Europe’s temperate species survived the Pleistocene glacial cycles in refugia north of the 20 Mediterranean peninsulas . For one such extra-Mediterranean refugia, the Carpathians, an intricate 21 ‘refugia-within-refugia’ scenario has been suggested, involving species surviving in multiple discrete 22 glacial refugia. We test the Carpathian refugia-within-refugia hypothesis, employing genome-wide 23 multilocus datasets for two newt species (Triturus cristatus and Lissotr iton montandoni). We fi rst use 24 Bayesian clustering to delineate intraspecific evolutionary lineages. The number of intraspecific 25 lineages identified, and the allocation of localities to these lineages, we re us d to construct testable 26 hypotheses on the spatial arrangement of glacial refugia in both newt species. Next we mploy 27 approximate Bayesian computation to date whether these lineages are of Holocene (< 12 Ka) or 28 Pleistocene (> 12 Ka) origin. We identify three intraspecific evolutionary lineages for T. cristatus and 29 two for L. montandoni. For both newt species, intraspecific divergence is rooted in the Pleistocene, in 30 line with species survival in distinct range fragments during the last glac ial period. Hence, our findings 31 firmly support the Carpathian refugia-within-refugia hypothesis. Furthermore, w e show that 32 mitochondrial DNA overestimates the age of intraspecific evolutionary lineag es nd we urge caution i 33 basing refugia-within-refugia scenarios on mitochondrial DNA alone. 34 35
Plant Traits of Phalaris Arundinacea and Phragmites Australis – Examining Effects of Water Level, Salinity, and Soil Types in a Mesocosm Experiment

Andreas Dahlkamp (  a.dahlkamp@tu-braunschweig.de ) TU Braunschweig: Technische Universitat Braunschweig https://orcid.org/0000-0003-2301-1506 Maike Heuner German Federal Institute of Hydrology: Bundesanstalt fur Gewasserkunde Stefanie Nolte University of East Anglia School of Environmental Sciences Jana Carus German Federal Institute of Hydrology: Bundesanstalt fur Gewasserkunde Kai Jensen Universität Hamburg: Universitat Hamburg Boris Schröder TU Braunschweig: Technische Universitat Braunschweig
Crystal structure of plant legumain reveals a unique two-chain state with pH-de- pendent activity regulation

The vacuolar cysteine protease legumain can cleave and selectively rebuild peptide bonds, thereby vastly expanding the sequential repertoire of biomolecules. In this context, plant legumains have recently attracted particular interest. Furthermore, legumains have important roles in many physiological processes, including programmed cell death. Their efficient peptide bond ligase activity has gained tremendous interest in the design of cyclic peptides for drug design. However, the mechanistic understanding of these dual activities is incomplete and partly conflicting. Here we present the crystal structure of a plant legumain, Arabidopsis thaliana isoform-γ (AtLEGγ). Employing a conserved legumain fold, the plant legumain AtLEGγ revealed unique mechanisms of auto-activation, including a plant-specific two-chain activation state, which remains conformationally stable at neutral pH, which is a prerequisite for full ligase activity and survival in different cell compartments. The charge distribution around the α6-helix mediates the pH-dependent dimerization and serves as a gatekeeper for the active site, thus regulating its protease and ligase activity. Plant Cell Advance Publication. Published on February 16, 2018, doi:10.1105/tpc.17. 00963 ©2018 The Authors. All Rights Reserved
GA Optimization of a Sliding Mode Controller for an Underactuated System

In this paper we develop a robust controller for the stabilization of a class of Underactuated Mechanical Systems. First we develop a static State Feedback Controller with inner noncollocated partial feedback linearization controller to stabilize the nominal system. Second, we develop a robust control based on the variable structure control theory to maintain system stabilization of the uncertain system by an appropriate choice of the sliding surface. The GA technique is used to tune optimally the VSS controller parameters to best meet output performances. Simulation results made on a 2-DOF whirling pendulum are given to illustrate our approach. Key-Words: underactuated, whiling pendulum, optimization, sliding mode, genetic algorithms.
Applying the Combination Forecasting Model to Estimate the Number of Visitors for National Scenic Area: Evidence from Taiwan

This study proposes to use the four steps from Box-Jenkins to set up ARMA and ARIMA models, and use the method of least squares regression to analyze the number of visitors to the Taiwan national scenic areas. In addition, the forecast performance of the combination forecasting model is also taken into account. The regression will analyze the influence of CPI, GDP, and seasonal indices on previous year s and this year s numbers of tourists to national scenic areas in Taiwan. We will also find the peak season, and analyze whether the dissemination of information has any impact on the number of tourists. The forecast performance of all the proposed models by the MAPE values, Taylor coefficients, R and adj-R will also be investigated.
Intraoperative neurophysiologic monitoring in microvascular decompression for hemifacial spasm

The majority of primary hemifacial spasm (HFS) patients are related to a vascular compression of the facial nerve root at its entry zone. Non-surgical treatment methods of HFS are anti-epileptic drugs and local botulinum toxin injection, but their outcomes are often not satisfactory in relieving symptoms. Microvascular decompression (MVD) is a surgical treatment method of HFS. Nowadays, intraoperative neurophysiologic monitoring is being used during MVD for two main objectives. The first and main objective is to prevent and reduce the risk of hearing impairment. Brainstem auditory evoked potentials (BAEPs) is monitored during surgery, to monitor the cranial nerve VIII and determine hearing sense preservation. Researches on BAEPs has enabled near real-time and safe monitoring, as warning indicators and advanced techniques to get results faster has been discovered. The second objective is to optimize the effectiveness of surgery. Despite the surgery, some patients had persisted symptoms or recurrence of spasm for some reasons, in few cases. The lateral spread response (LSR) monitoring is performed to guide the operator during surgery. LSR shows modest sensitivity. Nevertheless, it shows high specificity in predicting the symptom-free status after MVD. Low sensitivity precluded the use of the LSR monitoring as an exclusive solitary diagnostic modality. The disappearance of LSR during MVD appears to be not effectively in predicting long-term outcomes, but it demonstrated limited prognostic values in predicting favorable short-term outcomes. These results implements that, intraoperative monitoring of LSR during MVD can provide considerable value for investigating the adequacy of MVD before cranial bone closure.
Logarithmic corrections to N = 4 and N = 8 black hole entropy : a one loop test of quantum gravity

We compute logarithmic corrections to the entropy of supersymmetric extremal black holes in N = 4 and N = 8 supersymmetric string theories and find results in perfect agreement with the microscopic results. In particular these logarithmic corrections vanish for quarter BPS black holes in N = 4 supersymmetric theories, but has a finite coefficient for 1/8 BPS black holes in the N = 8 supersymmetric theory. On the macroscopic side these computations require evaluating the one loop determinant of massless fields around the near horizon geometry, and include, in particular, contributions from dynamical four dimensional gravitons propagating in the loop. Thus our analysis provides a test of one loop quantum gravity corrections to the black hole entropy, or equivalently of the AdS2/CFT1 correspondence. We also extend our analysis to N = 2 supersymmetric STU model and make a prediction for the logarithmic correction to the black hole entropy in that theory.