Miracle-dz/UniFAR-FTUs huggingface dataset:
FARMED AND WILD-CAUGHT SHRIMP IN KENTUCKY AND SOUTH CAROLINA: CONSUMER PREFERENCE FOR HOMEGROWN BY HEROES, COMMUNITY SUPPORTED FISHERY, AND OTHER QUALITY ATTRIBUTES

As information regarding origin, production method, and environmental certifications characterize a progressing seafood market, scare analysis has been made to understand market responses. This study focuses on consumer preference for wild-caught and farm-raised shrimp with several attributes. These include the Homegrown By Heroes label and Best Aquaculture Practices certification, as well as other existing attributes including the Marine Stewardship Council and each state’s local label. Also considered are hypothetical labels including Community Supported Fishery (CSF) and National Oceanic & Atmospheric Administration (NOAA). This study surveys consumers in Kentucky and South Carolina while utilizing a choice experiment to elicit willingness-to-pay measures for these various product attributes. Both wild-caught and farm-raised shrimp are considered since these species have significant market potential. Like previous studies, a strong preference for fresh as well as local shrimp was found. Furthermore, preference for Homegrown By Heroes was found to be highly valued by consumers, as well as the NOAA label signifying a federally operated ecolabel. Consumers were also found to value BAP and MSC certifications, two third-party agencies currently existent in the seafood market. Marketing and policy recommendations are given based on consumer willingness to pay estimates for these various seafood attributes in both states.
In silico and in vitro studies : Tryparedoxin Peroxidase inhibitor activity of methotrexate for antileishmanial activity

In order to understand the mechanism of molecular i nteractions at the active site of Tryparedoxin Pero xidase (Try P), homology modeling and docking studies were performed. We generated a Three-Dimensional (3D) model of target protein based on the Crystal struct ure of Leishmania Major Try PI (PDB ID: 3TUE) using modeler software. Docking analysis was carried out to study the effects of methotrexate on Tryparedoxi n Peroxidase (Try P). Inhibition of the Tryparedoxin peroxidase interaction has become a new therapeutic strategy in treating leishmaniasis. Docking analysi s was carried out to study the effects of methotrex ate on Tryparedoxin Peroxidase (TryP). Tryparedoxin peroxidase of Trypanosomatidae family functions as antioxidant through their peroxidase and peroxynitr ite reductase activities. The theoretical docking s tudy, conducted on a sample previously reported for anti- cancer properties of Methotrexate at the binding si te of 3D models of Tryparedoxin Peroxidase of Leishmania braziliensis (L. braziliensis Try P) examine interaction energy. Our studies indicate that Methotrexate disp lays potent activity against Try P with lowest bind ing energy and RMSD values to be -14.5879 Kcal/Mol and 2.0 A. The results of the present study clearly demonstrated the Tryparedoxin Peroxidase inhibitory activity by methotrexate in in silico docking analysis and in vitro assay which contributes towards understanding the mechanism of antileishmanial activity.
Roadmap to Alzheimer ’ s Biomarkers in the Clinic The biomarker-based diagnosis of Alzheimer ’ s disease . 1 d ethical and societal issues

There is great interest in the use of biomarkers to assist in the timely identification of Alzheimer’s disease (AD) in individuals with mild symptoms. However, the inclusion of AD biomarkers in clinical criteria poses socioethical challenges. The Geneva Task Force for the Roadmap of Alzheimer’s Biomarkers was established to deliver a systematic strategic research agenda (aka roadmap) to promote efficient and effective validation of AD biomarkers and to foster their uptake in clinical practice. In this article, we summarize the workshop discussion of the Geneva Task Force “ethical and societal issues” working group, which comprised bioethicists, clinicians, health economists, and representatives of those affected by AD. The working group identified the following key issues that need to be included in the roadmap: improving access to services through timely diagnosis, the need for a diagnostic research protocol before moving to clinical routine, recruitment in diagnostic research protocols in the absence of effective therapy, respect for the autonomy of the individual with mild cognitive impairment in information and consent process and the right not to know biomarkers results, need for counseling programs, disclosure of the diagnosis in a structured environment and the involvement of family members, health policies including the individuals’ views and the protection of their interests, and the economic costs for society. 2016 Elsevier Inc. All rights reserved.
Pointless Diversity Training: Unconscious Bias, New Racism and Agency

The latest fashion of ‘unconscious bias training’ is a diversity intervention based on unproven suppositions and is unlikely to help eliminate racism in the workplace. Knowing about bias does not automatically result in changes in behaviour by managers and employees. Even if ‘unconscious bias training’ has the theoretical potential to change behaviour, it will depend on the type of racism: symbolic/modern/colour-blind, aversive or blatant. In addition, even if those deemed racist are motivated to change behaviour, structural constraints can militate against pro-diversity actions. Agency is overstated by psychology-inspired ‘unconscious bias training’ proponents, leading them to assume the desirability and effectiveness of this type of diversity training intervention, but from a critical diversity perspective (sociologically influenced) the training looks pointless.
Corporate Governance Disclosure of Banks in Romania and Malaysia and the Quality of the Web Sites

This paper is aimed to explore and compare disclosure on corporate governance mechanisms in the annual reports of commercial banks for two emerging countries: Romania and Malaysia. There were selected 34 banks situated in Romania and Malaysia, in order to highlight the influence of culture and the impact of the size, profitability on corporate governance disclosure practices. Another objective is to determine the quality of the web sites of these banks and their ability to support the access to corporate governance elements. It is found that Malaysian banks provide more corporate governance information than Romanian banks, the quality of web sites being higher in case of Romanian banks. The conducted study highlights the tendency of more profitable banks to disclose more information on corporate governance than less profitable financial institutions, while the size of the banks does not appear to influence the value of the corporate governance disclosure index.
Cloning and characterization of functional keratin- associated protein 5-4 gene in maize

Keratin-associated proteins (KAPs) 5-4 which belongs to keratin-associated protein (KRTAP) type 5 family has two major groups: high/ultrahigh cysteine (HS) and high glycine-tyrosine (HGT). Based on bioinformatic prediction, we experimentally cloned a fragment containing an open reading frame of 1849 bp from maize, which encodes a protein of 408 amino acids. BLAST analysis indicated that KAP5-4 is homologous to the qPE9-1 protein in rice. Conserved domains analysis predicted the presence of five domains. Real time reverse transcriptase polymerase chain reaction (RT-PCR) indicated that the expression of this gene is up-regulated in response to water-deficit stress in the root and leaf.
The Effect of Sex and Background on Doxorubicin-Induced Cardiotoxicity in Carbonyl Reductase 1 +/- Mice: A Comparative Study

Doxorubicin has long been used clinically to treat a variety of cancers. Unfortunately, its success is limited due to its cardiotoxic side effects, restricting the cumulative dose that can be given to patients. It is known that the enzyme carbonyl reductase 1 (Cbrl) metabolizes this cancer drug in vivo, leading to the production of its toxic alcohol metabolite, doxorubicinol. A previous study has indicated that decreasing the expression level of carbonyl reductase 1 in male Cbr 1 +Imice provided them with significant protection from doxorubicin-induced cardiotoxicity when compared to their wild type littermates. With the intent to identify whether the protection conferred by knocking out one copy of Cbr 1 persists in a more diverse population, this subsequent study expanded the previous one to include female mice as well as mice of different genetic backgrounds. It was discovered that the protective effect conferred by a null Cbr 1 allele is no longer present, that females survive significantly longer than males, and that survival is no longer significantly associated with cardiotoxicity. Western blotting, subclinical pathogen analysis, histology, and pedigree analysis were performed in an effort to discover an explanation for the unexpected results. It is believed that alternate acute toxicity such as leukopenia was responsible for mouse death, whereas such factors are controlled in human clinical trials. In the event that decreased Cbr 1 levels provide significant cardiac protection, a Cbrl inhibitor could be created to be taken simultaneously with doxorubicin.
cyb-1 , a C . elegans B-type cyclin , maintains proper position and number of centrosomes during spermatogenesis

Depletion of cyb-1, a major B-type cyclin expressed during C. elegans spermatogenesis, caused a meiotic division arrest in diakinesis-stage spermatocytes with multiple and mispositioned centrosomes. Association of SUN-1 and ZYG-12, two nuclear membrane proteins, is critical for centrosome–nuclear envelope attachment. We found that sun-1 depletion caused centrosome defects similar to those caused by cyb-1 depletion in diakinesisstage spermatocytes. In addition, Ser8 and Ser43 residues in SUN-1 were dephosphorylated in cyb-1-depleted diakinesis-stage spermatocytes. Nevertheless, dephosphorylation of these residues was not sufficient to reproduce the cyb-1-related centrosome defects. We then found that the ZYG-12::GFP signal in the nuclear envelope was significantly reduced in the cyb-1depleted diakinesis-stage spermatocytes. However, only mispositioned but not multiplied centrosomes were observed in zyg-12-mutant diakinesis-stage spermatocytes, suggesting that zyg-12 is not involved in the centrosome duplication at this stage. CYB-1 possibly serves a novel function to maintain proper positioning of centrosomes during the spermatogenesis by regulating phosphorylation of SUN-1, which is conceivably critical for the association between SUN-1 and ZYG-12. This phosphorylation of SUN-1 may be also critical to regulate centrosome duplication independent of ZYG-12. Jo ur na l o f C el l S ci en ce • A dv an ce a rt ic le
A wider audience: Turning VLBI into a survey instrument

Radio observations using the Very Long Baseline Interferometry (VLBI) technique typically have fields of view of only a few arcseconds, due to the computational problems inherent in imaging larger fields. Furthermore, sensitivity limitations restrict observations to very compact and bright objects, which are few and far between on the sky. Thus, while most branches of observational astronomy can carry out sensitive, wide-field surveys, VLBI observations are limited to targeted observations of carefully selected objects. However, recent advances in technology have made it possible to carry out the computations required to target hundreds of sources simultaneously. Furthermore, sensitivity upgrades have dramatically increased the number of objects accessible to VLBI observations. The combination of these two developments have enhanced the survey capabilities of VLBI observations such that it is now possible to observe (almost) any point in the sky with milli-arcsecond resolution. In this talk I review the development of wide-field VLBI, which has made significant progress over the last three years (© 2012 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim)
Dipeptidyl peptidase IV inhibitory properties of a whey protein hydrolysate : influence of 1 fractionation , stability to simulated gastrointestinal digestion and food-drug interaction 2 3

a Department of Life Sciences and Food for Health Ireland (FHI), University of Limerick, 6 Castletroy, Limerick, Ireland 7 8 9 Please cite as: Nongonierma, A. B. & FitzGerald, R. J. (2013). Dipeptidyl peptidase IV inhibitory properties of a whey protein hydrolysate: Influence of fractionation, stability to simulated gastrointestinal digestion and food-drug interaction. International Dairy Journal, 32, 33–39. 10 11 12 13 14
A rst-order primal-dual algorithm for convex problems with applications to imaging

In this paper we study a rst-order primal-dual algorithm for convex optimization problems with known saddle-point structure. We prove convergence to a saddle-point with rate O(1/N) in nite dimensions, which is optimal for the complete class of non-smooth problems we are considering in this paper. We further show accelerations of the proposed algorithm to yield optimal rates on easier problems. In particular we show that we can achieve O(1/N) convergence on problems, where the primal or the dual objective is uniformly convex, and we can show linear convergence, i.e. O(1/e ) on problems where both are uniformly convex. The wide applicability of the proposed algorithm is demonstrated on several imaging problems such as image denoising, image deconvolution, image inpainting, motion estimation and image segmentation.
Sensation Animation Stronger Reward Excited Expected Reward Confirm Weaker Reward Happy Unexpected Reward Arrogant Negligible Think Unexpected Punishment Shocked Weaker Punishment Apologise Expected Punishment Angry Stronger Punishment Scared Table 1

Affect sensitivity is of the utmost importance for a robot companion to be able to display socially intelligent behaviour, a key requirement for sustaining long-term interactions with humans. This paper explores a naturalistic scenario in which children play chess with the iCat, a robot companion. A person-independent, Bayesian approach to detect the user’s engagement with the iCat robot is presented. Our framework models both causes and effects of engagement: features related to the user’s non-verbal behaviour, the task and the companion’s affective reactions are identified to predict the children’s level of engagement. An experiment was carried out to train and validate our model. Results show that our approach based on multimodal integration of task and social interaction-based features outperforms those based solely on non-verbal behaviour or contextual information (94.79 % vs. 93.75% and 78.13%).
A Saliency Detection Technique Considering Self- and Mutual-Information

In this paper, we present a novel approach to saliency detection. We define a visually sa- lient region in an image with following two properties; global spatial redundancy, i.e., mutu- al-information, and local saliency, i.e., self-information or simply the region complexity. The former is its probability of occurrence within the image, whereas the latter defines how much information is contained within a region, and it is quantified by the entropy. By combining the global spatial redundancy measure and local entropy, we can achieve a simple, yet robust saliency detector. We evaluate it quantitatively and qualitatively. The comparison to Itti et al. (6), the spectral residual approach by Hou and Zhang (5), Achanta et al. (13) as well as to Zhai and Shah (14), on publicly available data shows a significant improvement.
A Holistic Approach to Consumer Research on Expectations Regarding Animal Husbandry

Based on existing literature this paper reviews expectations of consumers, producers, other interest groups and citizens with respect to animal welfare and animal husbandry and indicates knowledge gaps as well. Findings enable us to develop a holistic research approach to analyse consumers’ and other interest groups’ preferences, expectations and concerns as well as requests of citizens. In order to reduce the gap between different perspectives regarding modern animal husbandry, these results will be used to improve communication between farmers and consumers or the society, respectively. It will facilitate the necessary integration of social concerns in the development of animal husbandry systems. An interdisciplinary network of researchers is aimed at.
A SEARCH FOR POINT SOURCES OF EeV PHOTONS

Measurements of air showers made using the hybrid technique developed with the fluorescence and surface detectors of the Pierre Auger Observatory allow a sensitive search for point sources of EeV photons anywhere in the exposed sky. A multivariate analysis reduces the background of hadronic cosmic rays. The search is sensitive to a declination band from −85° to +20°, in an energy range from 1017.3 eV to 1018.5 eV. No photon point source has been detected. An upper limit on the photon flux has been derived for every direction. The mean value of the energy flux limit that results from this, assuming a photon spectral index of −2, is 0.06 eV cm−2 s−1, and no celestial direction exceeds 0.25 eV cm−2 s−1. These upper limits constrain scenarios in which EeV cosmic ray protons are emitted by non-transient sources in the Galaxy.
RECOMMENDER SYSTEMS FOR CALL CENTERS

Insurance riders are optional addendum to base insurance policies. In this paper we discuss the application of recommender systems to the task of matching riders to clients. This task is difficult because of the variety of possible riders, as well as the poor knowledge of the client over these riders. We focus on call centers where the agent also has limited knowledge and expertise. For such agents, discovering appropriate riders for the current client is very difficult, and automated tools that suggest such riders can play an important role in the agent-client dialogue, and may influence considerably the outcome of the interaction. This paper presents and discusses in detail the problem of recommending insurance riders to clients in call centers, comparing it to other, classic, recommendation system applications. In addition, we present an analysis of customer purchase behavior, showing that simple item-item recommendation algorithms provide good recommendations for riders given a base policy.
InfoCage - : Information leakage protection software

We have developed InfoCage, which is an information leakage protection software product. InfoCage is a security solution that prevents information leakage from an organization by limiting the confidential data move operations performed by users who are authorized to access secure servers. This paper focuses on the data move control function, which is one of the technical features of the product.
VISITOR STRUCTURE AS A BASIS FOR DESTINATION REPOSITIONING - THE CASE OF A NORTH MEDITERRANEAN DESTINATION

In order to avoid the phase of decline, many North Mediterranean 3S destinations have been trying to reposition in the tourism market. However, the repositioning many times lacks sound market analysis. In this regard, the liaison between market repositioning strategy and push motivation-based market segments of visitors in summer season was studied for the case of the North Mediterranean 3S destination Portoro. In-depth quantitative survey on summer foreign leisure visitors was conducted for this purpose. The results show that repositioning efforts are not congruent with the structure of leisure visitors attracted to Portoro in summer season as they are still prevailingly motivated by 3S-based push motivations. Destination Portoro has actually not been repositioned in the market; it has only diversifi ed its tourism products. In conclusion, possible implications of these fi ndings for DMO’s are suggested.
Evaluation of dexmedetomidine alone and its combination with ketamine and ropivacaine for tube cystostomy in urolithic buffalo calves

The present study was conducted to evaluate clinicophysiological and biochemical effects of dexmedetomidine and its combination with ketamine and ropivacaine for tube cystostomy in urolithic buffalo calves. The study was conducted on 15 male buffalo calves of 3 to 4 months of age having the body weight of 40 to 50 kg which were suffering from urinary obstruction for 2 to 4 days. The animals were divided into three groups viz. D, DK and RDK on the basis of anesthetic agent(s) used. In Group D-dexmedetomidine 7.5 μg/kg, in Group DK- dexmedetomidine and ketamine 3.75 μg/kg and 2 mg/kg, respectively, and in Group RDK-ropivacaine, dexmedetomidine and ketamine 0.15 mg/kg, 2.5 μg/kg and 2 mg/kg, respectively, were administered subarachnoidally at lumbosacral space. In all the groups the onset of analgesia, extent and depth of analgesia at tail, perineum, inguinal region, thigh, digits, anterior flank, posterior flank, lower abdomen and thorax were recorded up to 90 minutes. The clinical examination revealed earliest onset of analgesia inGroup DK followed by Group RDK and Group D. However, duration of analgesia was similar in all the groups. Motor incoordination was recorded earlier in DK and RDK groups. Recovery time was shortest in dexmedetomidine (128.80±5.11 minutes) alone. Heart rate and respiratory rate decreased in all the groups. Rectal temperature decreased significantly in all the groups. Plasma glucose increased significantly in all the groups. However, plasma urea nitrogen and plasma creatinine values did not change significantly. It was concluded that RDK group provides better extent and depth of subarachnoid analgesia than D and DK with only transient and minor changes in physiological and biochemical parameters and therefore, could be used safely for tube cystostomy in urolithic buffalo calves.
Joint analysis of intervalcensored intervalcensored intervalcensored failure time data and panel count data

Interval-censored failure time data and panel count data are two types of incomplete data that commonly occur in event history studies and many methods have been developed for their analysis separately (Sun in The statistical analysis of interval-censored failure time data. Springer, New York, 2006; Sun and Zhao in The statistical analysis of panel count data. Springer, New York, 2013). Sometimes one may be interested in or need to conduct their joint analysis such as in the clinical trials with composite endpoints, for which it does not seem to exist an established approach in the literature. In this paper, a sieve maximum likelihood approach is developed for the joint analysis and in the proposed method, Bernstein polynomials are used to approximate unknown functions. The asymptotic properties of the resulting estimators are established and in particular, the proposed estimators of regression parameters are shown to be semiparametrically efficient. In addition, an extensive simulation study was conducted and the proposed method is applied to a set of real data arising from a skin cancer study.
International meeting of the French society of neurology 2013 Aphasia ( s ) in

Language disorders of degenerative origin are frequently tied to Alzheimer disease (AD) the different variants of which can result in primary and secondary aphasia syndromes. More specifically, Alzheimer pathology can primarily erode frontal, temporal or parietal language cortices resulting in three genuine AD language variants which account for about 30% of primary degenerative aphasias. Likewise, it can spread from non-language to language cortices leading to secondary language disorders like in typical amnesic AD and in several atypical AD variants. This paper reviews the whole set of AD variants by characterising their impact on the neural language system and on linguistic functioning. It also provides cues for diagnostic strategies which are essential for linguistic, syndromic and nosological patient classification, for adequate clinical follow-up and for guiding language rehabilitation. Such diagnostic approaches, founded on detailed linguistic phenotyping while integrating anatomical and neuropathological findings, also represent a crucial issue for future drug trials targeting the physio-pathological processes in degenerative aphasias. # 2013 Elsevier Masson SAS. All rights reserved.