Miracle-dz/UniFAR-FTUs huggingface dataset:
Laparoscopy in Pediatric Abdominal Trauma

Background: The use and indications for laparoscopy have been increasing. As part of this trend, a new algorithm may emerge for pediatric trauma in which laparoscopic techniques are used in hemodynamically stable patients with suspected hollow viscus perforation. Case Report: We present a case in which laparoscopy was successfully used in a pediatric trauma patient as a diagnostic and therapeutic modality. A 4-year-old boy was a back-seat passenger in a head-on collision motor vehicle accident. He was restrained by a lap seat belt. He sustained a concussion, a large forehead laceration and a seat belt abdominal injury. On admission, he complained of abdominal pain. Physical examination revealed a soft, nondistended abdomen with moderate diffuse tenderness. He was hemodynamically stable. Computerized tomography of the abdomen revealed free fluid in the pelvis. No abnormalities were detected in the liver or spleen. Because of clinical deterioration and suspected intestinal perforation, diagnostic laparoscopy was utilized instead of proceeding directly to celiotomy. At laparoscopy a jejunal perforation was found and successfully repaired laparoscopically. Large hematomas were seen in the mesentery, as well as an unsuspected splenic laceration. No active bleeding was found. The patient recovered uneventfully and was discharged 5 days following the surgical procedure. Conclusion: This case illustrates the efficacy of using early laparoscopy in children with abdominal trauma when diagnosis is difficult and hollow viscus injury is suspected.
Exploring Transition through the Senior Year Experience

Senior year is a busy time for most college students as they are preparing for their upcoming transition into adulthood. They are constantly answering the question “What are you doing after graduation? ” This results in many college seniors pulling away from their community in order to focus strictly on their major field of study and less on their upcoming transition (Henscheid, 2008). Senior Year Experience programs are a way colleges can provide intentional programming to support college students throughout this transition into adulthood. The purpose of this study was to explore existing Senior Year Experience programs at other institutions with the intention of implementing a new program at Merrimack College. Focus groups involving senior students at Merrimack were conducted, to explore the resources these students have utilized on campus, and to document what they are most nervous about in their upcoming transition. The findings indicated that a Senior Year Experience or transitional program is necessary at this institution, and that many students requested support in areas such as life skills, counseling, maintaining relationships, and professional etiquette. The conclusion of this study recommends a senior retreat experience to be implemented through collaboration with various offices on Merrimack’s campus. EXPLORING TRANSITION 3
Application of Broselow Tape in Pediatric Population Ex- posed to Chemical Terrorism

To investigate the applicability of the Broselow Emergency Pediatric tape in disaster response for pediatric population, we underwent a study in a NBC training course. The 83 students were randomly subgrouped as Group A (n=41) and Group B (n=42). The former were supplied with the Broselow Emergency Pediatric tape and the latter were not supplied. A 20-item questionnaire containing questions concerning management of different conditions from pediatric population was fulfilled from each student. The average score was 83+9 points for Group A and 77+8 points for Group B (P<0.01). he causes of errors were categorized as misuse of agents, dosing errors, and missing data. There are significant differences in dosing errors judged by absolute scores between Group A and Group B (11+4 points vs 19+5 points, P<0.05) whereas no differences were met in misuse of agents (3+4 points vs. 4+5 points, P=NS) and in missing data (3+5 points vs. 1+3 points, P=NS). In the viewpoint of relative contribution of errors, misuse of agents contribute to 18+5% for Group A and 17+5% for Group B (P=NS). In addition, there was significant difference in the percentage of dosing errors between Group A and Group B (65+18% vs. 83+21%, P<0.05). There was also significant difference in relative contribution from missing data (18+7% vs. 4+5%, P<0.01). In conclusion, the main pitfall of Broselow Emergency Pediatric tape was lacking the information of antidotes for cyanide, radiation agents and biological agents. A modified Broselow Emergency tape should be needed to resolve such a dilemma. (Ann Disaster Med. 2006;4:49-53)
2,6-Di­chloro-4-nitro­toluene

The title compound, C7H5Cl2NO2 [systematic name: 1,3-di­chloro-2-methyl-5-nitro­benzene], crystallizes in the chiral space group P212121 with a Flack parameter of −0.03 (5). The methyl C atom, the Cl atoms and the N atom of the nitro substituent all lie extremely close to the plane of the benzene ring; the deviations are 0.028 (3) A for the methyl C atom, −0.016 (1) and 0.007 (1) A for the two Cl atoms, and −0.017 (3) A for the nitro N atom. Hence, no significant steric hindrance of the methyl group by the ortho halogen atoms is observed. The nitro group is inclined to the benzene ring by 9.8 (3)°. In the crystal, mol­ecules are linked by weak C—H⋯O and C—H⋯Cl hydrogen bonds, forming layers parallel to the ab plane.
The Griffith Area Palliative Care Service (GAPS): an evaluation of an Australian rural palliative care model

Abstract Quantitative and qualitative data, including service utilisation, health records, a provider survey and participant observation, were used to describe the impact of a new model of palliative care on patients, carers and staff in rural Australia. A total of 95 patients were enrolled between October 2001 and February 2003, for an average of 147 days. Deaths per month averaged 3.5. Participating general practitioners were positive about the model. The experiences of 14 patients or carers and 3 people who had cared for a relative with terminal illness prior to the new model were also positive. As one illustration, patients and carers commented that trips to the emergency department prior to the GAPS programme often involved long waiting times and unnecessary investigations and that this had now improved. The elements of the model that worked most effectively were weekly case conferences, the on-call nursing roster, patient-held records and shared protocols and procedures. The model achieved its aim of improving palliative care services and still continues with some modifications. The generalisability of the model is now being tested in eight rural and remote communities across Australia.
Clinical Exercise Physiology COMPARISON OF CHANGES IN EXERCISE TOLERANCE AND QUALITY OF LIFE BETWEEN CONGESTIVE HEART FAILURE AND CORONARY ARTERY BYPASS GRAFT PATIENTS FOLLOWING A HOSPITAL-BASED CARDIAC REHABILITATION PROGRAM

COMPARISON OF CHANGES IN EXERCISE TOLERANCE AND QUALITY OF LIFE BETWEEN CONGESTIVE HEART FAILURE AND CORONARY ARTERY BYPASS GRAFT PATIENTS FOLLOWING A HOSPITAL-BASED CARDIAC REHABILITATION PROGRAM. Craig Brubaker, E. Lea Witta, Theodore J. Angelopoulos. JEPonline. 2003;6(1):18-23. Few studies have compared cardiac rehabilitation program outcomes between individuals with congestive heart failure (CHF) and post coronary artery bypass graft (CABG), perhaps due to the lack of insurance reimbursement for a CHF diagnosis. Therefore, we examined the exercise tolerance and quality of life outcomes for 56 individuals with CHF (age=73±9 yrs; ejection fraction=34±11%) and 52 individuals post CABG (age=73±7 yrs; ejection fraction=57±10 %) following a 12-week cardiac rehabilitation program, respectively. Both groups exercised a minimum of 24 sessions over 12-weeks while attending up to 12 educational seminars. Preand postexercise tolerance was measured by a graded treadmill test and quality of life was assessed using the SF-36 Health Survey. Following the 12-week cardiac rehabilitation program there were significant improvements in exercise tolerance in individuals with CHF (163±61 to 251±70 s; p<0.01) and CABG (208±62 to 309±90 s; p<0.01). All nine quality of life constructs improved significantly (p<0.01) within both groups. There were no significant differences in exercise tolerance or quality of life between groups (p=0.17). Furthermore, a positive and significant correlation was found between exercise tolerance and patient perceived physical function (R=0.34, p<0.01). The data presented in this study suggest that patients with CHF can safely benefits from cardiac rehabilitation and that their outcomes are similar to patients post CABG.
Heterotopic Cervical Pregnancy

We report a rare case of heterotopic cervical pregnancy, which posed diagnostic challenge. With increasing IVF treatment and raising cesarean section rate, there is increasing incidence for non-tubal heterotopic pregnancy. We have discussed the clinical course of our case, diagnosis and management of cervical pregnancy and some good medical practices to avoid missing atypical presentations of ectopic pregnancy. J Clin Gynecol Obstet. 2015;4(4):307-311 doi: http://dx.doi. org/10.14740/jcgo369w
Private Delivery Care in Developing Countries: Trends and Determinants

Over the past two decades multilateral organizations have encouraged increased engagement with private health care providers in developing countries. As these efforts progress there are concerns that private delivery care may have adverse effects on maternal health. Currently available data do not allow for an in-depth study of the direct effect of privatization on maternal health. However as a first step we can use Demographic and Health Surveys (DHS) data to examine a) trends in growth of delivery care provided by private facilities and b) determinants of private sector use within the health care system. To construct trends this study uses DHS from 16 sub-Saharan African Asian and Latin American countries selecting those countries with one DHS in phase 4 (1997–2003) and one in phase 5 (2003–present). For a subset of eight countries we examine determinants of a mothers choice to deliver in a health facility and then among women delivering in a facility their decision to use a private provider. Determinants of use are grouped by socioeconomic characteristics economic and physical access and by actual / perceived need. Results show a significant trend toward privatization of delivery care over the 13 years covered in the study but there is considerable variation in the characteristics driving this increased use across countries. In three African countries socio-demographic characteristics are associated with use of private delivery care while in Bolivia and four Asian countries economic indicators are more relevant. In the former this may suggest complementarity to public facilities (e.g. private delivery services cover populations that may not be reached by public services) while in the latter it may mean competition. These results warn against making generalizations on the effects of privatization on maternal health use.
Defining Elastic Fiber Interactions by Molecular Fishing AFFINITY PURIFICATION AND MASS SPECTROMETRY APPROACH* □ S

Deciphering interacting networks of the extracellular matrix is a major challenge. We describe an affinity purification and mass spectrometry strategy that has provided new insights into the molecular interactions of elastic fibers, essential extracellular assemblies that provide elastic recoil in dynamic tissues. Using cell culture models, we defined primary and secondary elastic fiber interaction networks by identifying molecular interactions with the elastic fiber molecules fibrillin-1, MAGP-1, fibulin-5, and lysyl oxidase. The sensitivity and validity of our method was confirmed by identification of known interactions with the bait proteins. Our study revealed novel extracellular protein interactions with elastic fiber molecules and delineated secondary interacting networks with fibronectin and heparan sulfate-associated molecules. This strategy is a novel approach to define the macromolecular interactions that sustain complex extracellular matrix assemblies and to gain insights into how they are integrated into their surrounding matrix. Molecular & Cellular Proteomics 8:2715–2732, 2009. Mass spectrometry is emerging as a powerful approach to identify protein interaction partners in molecular complexes. We have developed an affinity purification and mass spectrometry strategy that is applicable to the analysis of molecular interactions of extracellular matrix complexes. The extracellular matrix provides structural support to tissues and profoundly influences cell survival, proliferation, migration, and phenotypic state. It is a complex multimolecular and three-dimensional milieu that comprises assembled networks of tissue-specific combinations of structural and cell-adhesive glycoproteins, proteoglycans, and cross-linking enzymes. The matrix also sequesters numerous growth factors and cytokines, thereby controlling their bioavailability. Delineating the molecular nature of the fundamental in
Heat transfer during #ow and resin reaction through "ber reinforcement

An experimental analysis of heat transfer and resin reaction in #ow through "ber reinforcement is presented. The results from non-isothermal mold "lling experiments with and without resin reaction are compared with those from numerical simulation based on a mixed Eulerian}Langrangian approach. Heat transfer between the #uid and the "ber reinforcement is investigated using both one-temperature and two-temperature models with the thermal dispersion e! ect included. The prediction of the two-temperature model is shown to be in good agreement with experimental results. ( 2000 Elsevier Science Ltd. All rights reserved.
1,2-ジアシルグリセロール位置異性体のエレクトロスプレーイオン化質量分析

1,2-ジアシルグリセロール（1,2-DAG）の位置異性体（reverse isomers）を同定するためのエレクトロスプレーイオン化質量分析法を検討し，その特徴を明らかにした．不飽和度の異なる種々の異性体をジニトロフェニルウレタン（DNPU），ジニトロベンゾエート，ニコチネート及びアンスリルウレタンへ変換してスペクトルを測定した．その結果，MSでは，いずれの誘導体からも強い分子量関連イオン（[M-H]－又は [M＋Na]＋）が得られたが，構成脂肪酸由来のイオンは検出されなかった．一方，MS/MSでは，DNPUから [RCOO]－イオンが検出された．16 : 0や18 : 1など不飽和度の小さな脂肪酸を含む位置異性体のsn-2位由来の [R2COO]－の強度はsn-1（3）位由来の [R1COO]－よりも大きく，両異性体の識別が可能であった．一方，高度不飽和脂肪酸を含む異性体では，この差は小さく，20 : 4や22 : 6は結合位置にかかわらず脱離しやすいことが認められた．[RCOO]－イオンの生成機構について考察した．
Opposite long-term trends in aerosols between low and high altitudes: a testimony to the aerosol–PBL feedback

Abstract. Interactions between absorbing aerosols and the planetary boundary layer (PBL) play an important role in affecting air pollution near the surface. In this study, a unique feature of the aerosol–PBL interaction is identified that has important implications in monitoring and combating air pollution. Opposite trends in aerosol loading between the lower and upper PBL are shown on a wide range of timescales and data acquired by various platforms: from a short-term field experiment to decadal satellite observations and multidecadal ground observations in China. A novel method is proposed to obtain the vertical profiles of aerosol loading from passive sensors by virtue of varying elevations. The analyses of visibility, aerosol optical depth, and extinction with different temporal scales exhibit the similar trend, i.e., increasing in the lower atmosphere but decreasing in the upper atmosphere. Integration of the reversal aerosol trend below and above the PBL resulted in a much less change in the column-integrated quantities. The surface cooling effect, together with the change in the heating rate induced by the absorbing aerosol, unevenly modifies the atmospheric temperature profile, causing a more stable atmosphere inside the PBL but a destabilized atmosphere above the PBL. Such a change in the atmospheric stability favors the accumulation of pollutants near the surface and the vertical diffusion of aerosol particles in the upper atmosphere, both of which are consistent with the observed reversal aerosol trends. These findings have multiple implications in understanding and combating air pollution, especially in many developing countries with high emissions of light-absorbing aerosols.
Description des profils des hauts consommateurs d’un département d’urgence et mise en à l’essai d’une intervention infirmière pour optimiser la trajectoire de soins

Introduction. Patients who frequently use the emergency department (ED) negatively impact ED efficiency. In order to optimize the care trajectory of these frequent users (FU), we have looked for patterns in their use of health care and implemented an intervention adapted to the patterns found. Methodology. The characteristics that describe the patterns of FU health care use, where FU are patients that have visited the ED of the ultra-specialized cardiology hospital seven times or more during a one year period from 2012 to 2013, were chosen based on the theoretical framework of Andersen (2008). The data available in the medical records was collected from the hospital’s electronic databases and analyzed. The intervention, which aims at better understanding the pattern of health care use and patient needs, was developed based on the theoretical framework of Wagner (1998). Suitable patients, who visited the ED at least five times in 2013-2014, were identified for the intervention during one of their visits to the ED. Conclusion. To determine patterns of health care use, we found 31 FU, amassing a total of 272 ED visits. We have observed that the FU of the one year period studied were no longer FU the following year, as only two of them (13%) visited the ED seven times or more during the year after. Those FU who visited outpatient clinics, visited the ED less often than those who did not. Furthermore, the frequency of use and the accessibility of ambulatory care show that multiple FU suffered from chronic illness or severe comorbidity. For the intervention, we have selected and met with five patients. Most of them said they were worried about the consequences that their medical problems could have. However, very few of these patients declared themselves to be ready to change their daily habits in favor of better health. In order to improve care for these patients, individual and organizational interventions were recommended.
EFFECTS OF ARSENIC POISONING - AN OVERVIEW

Arsenic is a recognized cause of cancer, inhalation of high level of air borne arsenic causes lung cancer. It is also implicated in many other adverse health effects, including skin lesions, diabetes, chronic bronchitis, cardiovascular disease, peripheral neuropathy, adverse reproductive outcomes and hematological effects. Our review article mainly focused on arsenic poisoning, its severity and management of toxic exposure. We developed a search strategy to find publications about arsenic poisoning and its management. So, we searched Science Direct, Medline and PubMed bibliographic databases using the key phrases causes of Arsenic poisoning, diagnosis, management of arsenic poisoning and its treatment. Our review article examines pathophysiology, clinical manifestations, toxicokinetics of arsenic, its prevention and management. In future, there is a need to create awareness about the toxicity of arsenic among the people who are routinely getting exposed to arsenic.
SERUM AND SALIVARY MINERALS IN DENTAL CARIES

Background: Dental caries is a multifactor disease, affecting people of all ages. Inorganic mineral of serumand salva can also have protective role in dental caries. This study was carried out to evaluate and comparethe possible role o f salivary and serum factors like pH, adequate level of calcium, phosphate and fluoridein dental caries.Methodology: A Total of 100 subj ects aged 10-40 were selected. Decayed, missed and filled teeth (DMFT)were used as indices for scoring the dental caries and were distributed or divided into 4 groups on the basisofDMFT indices as 4-8 (Group I), 9-16 (Group II), 17-24 (Group III) and more than 25 (Group IV), whilethe control subj ects had DMFT index equal to or less than 3. pH, calcium, phosphate, fluoride and lacticacid were analyzed in saliva and serum.Results: Patients of dental caries showed significantly low levels of calcium, phosphate, fluoride (P<0.001)and significantly high level of lactic acid (P<0.001) in all the groups as compared to control subj ects.Prominent significant changes were observed in different groups. The salivary and serum pH, calcium,fluoride, phosphate and lactic levels were found to be significantly changed among the patients having dentalcaries.Conclusion: It can be concluded from the findings o f present study that the adequate levels o f calcium,phosphate and fluoride in saliva as well as serum are responsible for the significant deposition o f theseminerals in plaque which greatly reduces the developmental caries in the adj acent enamel.
Gene Therapy for Cancer: Is there Light at the End of the Tunnel?

Gene therapy is a novel modality of treatment which is being explored as a treatment option. Majority of the ongoing gene therapy clinical trials are for cancer, a disease difficult to treat with the existing therapies. Hence newer modalities of treatment are emerging. In cancer gene therapy, a gene or DNA is introduced into the tumour cell which would induce the tumour cell to die either directly or indirectly. Although this therapy is still in an experimental stage, it has shown some promise and there are at least two drugs for cancer which have been approved in China—the only country to have approved gene therapy based drugs. The different strategies of tumour cell kill as well as the various methods of gene delivery will be discussed in the following sections. For any new drug or treatment to be accepted in the clinics, it has to undergo rigorous clinical trials and approval by regulatory bodies. For gene therapy, it is a long and arduous path from research in laboratories to the clinics.
Smartphone apps in mental healthcare: the state of the art and potential developments

Summary Previous studies have demonstrated that smartphones are useful tools in everyday, evidence-based medical practice. This article gives an overview of the current use in psychiatry of smartphone apps aimed at patients and the general public, highlighting associated benefits and disadvantages. It also outlines how practising psychiatrists could embrace such technologies at an individual, organisational and national level.
Assessment of the left atrial longitudinal myocardial function by the strain and strain rate echocardiography in patients with rheumatic mitral stenosis

Results: For all 3 periods, all of the segment S values and most of the segment Sr values were signifi cantly lower in the patients than in the controls (P < 0.0001 and P < 0.05, respectively). Th ere were no signifi cant diff erences between the groups in terms of velocities. Time to peak S in the contractile and conduit periods was signifi cantly higher in the patients than in the controls, in most of the segments (P < 0.05). Time to peak Sr was signifi cantly higher in the patients than in the controls, in all of the periods in all of the segments (P < 0.05) except for mid-septal segments. Conclusion: Th is study demonstrated that LA longitudinal myocardial functions were impaired in MS patients with S/ Sr echocardiography. Our study is the fi rst to demonstrate prolonged time to peak S/Sr of the LA in rheumatic MS. Th is condition might be an additional factor in the deterioration of regional LA myocardial function in MS patients.