Miracle-dz/UniFAR-FTUs huggingface dataset:
Fine-Grained Pattern Matching Over Streaming Time Series

Pattern matching of streaming time series with lower latency under limited computing resource comes to a critical problem, especially as the growth of Industry 4.0 and Industry Internet of Things. However, against traditional single pattern matching problem, a pattern may contain multiple segments representing different statistical properties or physical meanings for more precise and expressive matching in real world. Hence, we formulate a new problem, called "fine-grained pattern matching", which allows users to specify varied granularities of matching deviation to different segments of a given pattern, and fuzzy regions for adaptive breakpoints determination between consecutive segments. In this paper, we propose a novel two-phase approach. In the pruning phase, we introduce Equal-Length Block (ELB) representation together with Block-Skipping Pruning (BSP) policy, which guarantees low cost feature calculation, effective pruning and no false dismissals. In the post-processing phase, a delta-function is proposed to enable us to conduct exact matching in linear complexity. Extensive experiments are conducted to evaluate on synthetic and real-world datasets, which illustrates that our algorithm outperforms the brute-force method and MSM, a multi-step filter mechanism over the multi-scaled representation.
Evaluation of the efficacy and safety of bazedoxifene/conjugated estrogens for secondary outcomes including vasomotor symptoms in postmenopausal women by years since menopause in the Selective estrogens, Menopause and Response to Therapy (SMART) trials.

BACKGROUND Bazedoxifene/conjugated estrogens (BZA/CE), a novel tissue-selective estrogen complex (TSEC), has been evaluated in the Selective estrogens, Menopause And Response to Therapy (SMART) trials. Secondary outcomes from these trials were evaluated to determine whether the effects of BZA/CE are influenced by years since menopause (YSM). METHODS SMART-1 and SMART-2 were randomized, double-blind, placebo (PBO)-controlled phase 3 trials in nonhysterectomized postmenopausal women. Outcomes were evaluated for women <5 or ≥5 YSM in SMART-1 (BZA 20 mg/CE 0.45 mg, n=433; BZA 20 mg/CE 0.625 mg, n=414; PBO, n=427) and SMART-2 (BZA 20 mg/CE 0.45 mg, n=127; BZA 20 mg/CE 0.625 mg, n=128; PBO, n=63). Hot-flush frequency and severity, health-related quality of life (HRQoL), sleep, treatment satisfaction, cumulative amenorrhea, and breast pain were assessed for each study individually, using defined statistical analysis protocols. RESULTS For <5 and ≥5 YSM subgroups, BZA 20 mg/CE 0.45 and 0.625 mg showed significant decreases in hot-flush frequency and severity at 3 months compared with PBO (p<0.05 for both). Both BZA/CE doses showed significant improvements compared with PBO in HRQoL scores, sleep parameters, and satisfaction with treatment at 3 months irrespective of YSM (p≤0.05 vs. PBO for all). Similar to PBO, BZA/CE showed high proportions of cumulative amenorrhea (SMART-1) and low incidences of breast pain (SMART-1 and SMART-2) for women <5 and ≥5 YSM. CONCLUSIONS The positive effects of BZA/CE on secondary outcomes were consistent among women <5 or ≥5 YSM.
A novel direct torque control for permanent magnet synchronous motor drive

To solve the problems of torque ripple and inconstant switch frequency of inverter in the conventional direct torque control (DTC) for permanent magnet synchronous motor (PMSM) drive, a novel DTC method using space vector pulse width modulation (SVM) is proposed based on analysis of PMSM mathematical model. In this novel DTC system of PMSM , traditional torque hysteresis controller and flux hysteresis controller is respectively substituted by PI controller , traditional switch table is substituted by SVM, and traditional PID used for speed controller is substituted by adaptive PID based on artificial neural network . The simulation model of the DTC system of PMSM is built based on MATLAB, simulation results verify the novel system proposed by this paper has faster dynamic response, lower torque ripple and lower flux ripple than traditional system.
Genetic and Physical Interaction Studies Reveal Functional Similarities between ALBINO3 and ALBINO4 in Arabidopsis1[OPEN]

A thylakoid membrane protein shares functional similarity and physical interactions with the homologous protein insertase, despite sequence-level divergence in a critical C-terminal domain. ALBINO3 (ALB3) is a well-known component of a thylakoid protein-targeting complex that interacts with the chloroplast signal recognition particle (cpSRP) and the cpSRP receptor, chloroplast filamentous temperature-sensitive Y (cpFtsY). Its protein-inserting function has been established mainly for light-harvesting complex proteins, which first interact with the unique chloroplast cpSRP43 component and then are delivered to the ALB3 integrase by a GTP-dependent cpSRP-cpFtsY interaction. In Arabidopsis (Arabidopsis thaliana), a subsequently discovered ALB3 homolog, ALB4, has been proposed to be involved not in light-harvesting complex protein targeting, but instead in the stabilization of the ATP synthase complex. Here, however, we show that ALB3 and ALB4 share significant functional overlap, and that both proteins are required for the efficient insertion of cytochrome f and potentially other subunits of pigment-bearing protein complexes. Genetic and physical interactions between ALB4 and ALB3, and physical interactions between ALB4 and cpSRP, suggest that the two ALB proteins may engage similar sets of interactors for their specific functions. We propose that ALB4 optimizes the insertion of thylakoid proteins by participating in the ALB3-cpSRP pathway for certain substrates (e.g. cytochrome f and the Rieske protein). Although ALB4 has clearly diverged from ALB3 in relation to the partner-recruiting C-terminal domain, our analysis suggests that one putative cpSRP-binding motif has not been entirely lost.
Motives and Health-related Behaviours

We investigated the phenomena of equipotentiality (one dispositional motive expressed through more than one behaviour) and equifinality (one behaviour serving more than one motive). In a cross-sectional survey, 244 young adults completed measures of sun-related behaviour and risky sexual behaviour, participatory motives for the behaviours and life goals (representing dispositional motives). Equipotentiality was demonstrated, in that power and diversity life goals each predicted more than one behaviour. Equifinality was demonstrated, in that sun exposure and risky sexual behaviour were each predicted by more than one life goal. Participatory motives mediated these relationships. Equipotentiality and equifinality need to be taken into account in health promotion.
Correction of astigmatism with Excimer laser transverse keratectomy

Abstract. Transverse keratectomies with the Excimer laser were performed on seven eyes of 4 patients with a mean, naturally occurring astigmatism of 5.32D (sd 1.0), range 4.25 to 7.0D. One month later mean astigmatism was 3.46D (sd 1.35), 3 months later 3.8D (sd 1.35), rising to 4.3D (sd 1.6) after 6 months, and to 4.68 (sd 1.4) after 1 year. The refractive cylinder was reduced from a mean of 5.8D to 4.5D and the mean unconnected visual acuity rose from 0.16 to 0.3. No serious complications occurred, and uncorrected visual acuity could be improved slightly. Excimer laser transverse keratectomy cannot be recommended as a good method to treat high degrees of naturally occurring astigmatism.
Joint workshop on bibliometric-enhanced information retrieval and natural language processing for digital libraries (BIRNDL 2016)

The large scale of scholarly publications poses a challenge for scholars in information-seeking and sensemaking. Bibliometric, information retrieval (IR), text mining and NLP techniques could help in these activities, but are not yet widely used in digital libraries. This workshop is intended to stimulate IR researchers and digital library professionals to elaborate on new approaches in natural language processing, information retrieval, scientometric and recommendation techniques which can advance the state-of-the-art in scholarly document understanding, analysis and retrieval at scale.
Risk of hospitalization or death from ischemic heart disease among British vegetarians and nonvegetarians: results from the EPIC-Oxford cohort study.

BACKGROUND Few previous prospective studies have examined differences in incident ischemic heart disease (IHD) risk between vegetarians and nonvegetarians. OBJECTIVE The objective was to examine the association of a vegetarian diet with risk of incident (nonfatal and fatal) IHD. DESIGN A total of 44,561 men and women living in England and Scotland who were enrolled in the European Prospective Investigation into Cancer and Nutrition (EPIC)-Oxford study, of whom 34% consumed a vegetarian diet at baseline, were part of the analysis. Incident cases of IHD were identified through linkage with hospital records and death certificates. Serum lipids and blood pressure measurements were available for 1519 non cases, who were matched to IHD cases by sex and age. IHD risk by vegetarian status was estimated by using multivariate Cox proportional hazards models. RESULTS After an average follow-up of 11.6 y, there were 1235 IHD cases (1066 hospital admissions and 169 deaths). Compared with nonvegetarians, vegetarians had a lower mean BMI [in kg/m(2); -1.2 (95% CI: -1.3, -1.1)], non-HDL-cholesterol concentration [-0.45 (95% CI: -0.60, -0.30) mmol/L], and systolic blood pressure [-3.3 (95% CI: -5.9, -0.7) mm Hg]. Vegetarians had a 32% lower risk (HR: 0.68; 95% CI: 0.58, 0.81) of IHD than did nonvegetarians, which was only slightly attenuated after adjustment for BMI and did not differ materially by sex, age, BMI, smoking, or the presence of IHD risk factors. CONCLUSION Consuming a vegetarian diet was associated with lower IHD risk, a finding that is probably mediated by differences in non-HDL cholesterol, and systolic blood pressure.
Energy substrates and amino acids provided during in vitro maturation of bovine oocytes alter acquisition of developmental competence

Energy substrates and amino acids were evaluated for supporting acquisition of developmental competence by bovine cumulus-oocyte complexes during in vitro maturation. The basic culture medium (Basic Medium-3) used for in vitro maturation of oocytes was modified to produce six media containing glucose or glutamine with lactate or pyruvate, or glucose + glutamine, or glucose + 11 amino acids; a seventh (control) medium was TCM199. All media contained polyvinyl alcohol, gonadotropins, epidermal growth factor and oestradiol. Following maturation, oocytes were incubated in medium TALP for fertilisation, then cumulus cells were removed and presumptive embryos cultured for 48 h in a chemically defined medium (HECM-6) followed by 120 h in medium TCM199 + bovine calf serum. Six substrate treatments yielded similar first cleavage responses (66-78%) at 72 h post-insemination; however, blastocyst development at 192 h varied significantly. Oocytes matured in medium with glucose + 11 amino acids gave the best blastocyst development: 21% of inseminated oocytes or 25% of 2-cell embryos. Cumulus expansion in HECM-6 required glucose with either glutamine, 11 amino acids or lactate, or glutamine + lactate. We conclude that (1) the type of energy substrate or nutrient supplied during in vitro maturation of oocytes profoundly affects subsequent developmental competence; (2) oocyte maturation in simple medium containing glucose with lactate or 11 amino acids or glutamine, or lactate + glutamine, can support development equally as well as the complex medium, TCM199; and (3) media supporting at least moderate cumulus expansion during oocyte maturation also support subsequent blastocyst development.
Traceback model for identifying sources of distributed attacks in real time

Locating sources of distributed attack is time-consuming; attackers are identified long after the attack is completed. This paper proposes a trackback model for identifying attackers and locating their distributed sources in real time. Attackers are identified by monitoring violations of malicious end users on their bandwidth shares predefined in the service level agreement. Then, active connections of the malicious users are investigated to locate the host machines used as distributed sources of attack traffic. Mathematical model and simulation results demonstrate that the proposed model can reduce the required time for identifying malicious users and locating host machines used as the actual sources of attack packets. Copyright © 2016 John Wiley & Sons, Ltd.
Effect of lugol solution on thyroid gland blood flow and microvessel density in the patients with Graves' disease.

CONTEXT Although some endocrine surgeons administer Lugol solution to decrease thyroid gland vascularity, there is still not an agreement on its effectiveness. OBJECTIVE The aims of this clinical trial are to evaluate thyroid blood flow and microvessel density in patients with Graves' disease who received Lugol solution treatment preoperatively. DESIGN This was a prospective clinical trial. SETTING This clinical trial took place at a tertiary referral center. METHOD Thirty-six patients were randomly assigned to receive either preoperative treatment with Lugol solution (group 1, n = 17) or no preoperative treatment with Lugol solution (group 2, n = 19). MAIN OUTCOME MEASURES Blood flow through the thyroid arteries of patients with Graves' disease was measured by color flow Doppler ultrasonography. The microvessel density (MVD) was assessed by immunohistochemical and Western blot analysis of the level of expression of CD-34 in thyroid tissue. The weight and blood loss of the thyroid gland were measured in all patients. RESULTS The mean blood flow, MVD, CD-34 expression, and blood loss in group 1 patients were significantly lower than those in group 2 patients. There was a negative correlation between Lugol solution treatment and blood flow (r(s) = -0.629; P = 0.0001), blood loss (r(s) = -0.621; P = 0.0001), MVD (r(s) = -0.865; P = 0.0001), and CD-34 expression (r(s) = -0.865; P = 0.0001). According to logistic regression analysis, Lugol solution treatment resulted in a 9.33-fold decreased rate of intraoperative blood loss. CONCLUSION Preoperative Lugol solution treatment decreased the rate of blood flow, thyroid vascularity, and intraoperative blood loss during thyroidectomy.
Fast AdaBoost-Based Face Detection System on a Dynamically Coarse Grain Reconfigurable Architecture

An AdaBoost-based face detection system is proposed, on a Coarse Grain Reconfigurable Architecture (CGRA) named “REMUS-II”. Our work is quite distinguished from previous ones in three aspects. First, a new hardware-software partition method is proposed and the whole face detection system is divided into several parallel tasks implemented on two Reconfigurable Processing Units (RPU) and one micro Processors Unit (µPU) according to their relationships. These tasks communicate with each other by a mailbox mechanism. Second, a strong classifier is treated as a smallest phase of the detection system, and every phase needs to be executed by these tasks in order. A phase of Haar classifier is dynamically mapped onto a Reconfigurable Cell Array (RCA) only when needed, and it's quite different from traditional Field Programmable Gate Array (FPGA) methods in which all the classifiers are fabricated statically. Third, optimized data and configuration word pre-fetch mechanisms are employed to improve the whole system performance. Implementation results show that our approach under 200MHz clock rate can process up-to 17 frames per second on VGA size images, and the detection rate is over 95%. Our system consumes 194mW, and the die size of fabricated chip is 23mm2 using TSMC 65nm standard cell based technology. To the best of our knowledge, this work is the first implementation of the cascade Haar classifier algorithm on a dynamically CGRA platform presented in the literature.
An improved particle swarm optimization algorithm for optimal reactive power dispatch

This paper presents an improved particle swarm optimization algorithm (IPSO) to optimal reactive power dispatch and voltage control of power systems. The improved particle swarm optimization approach uses more particles' information to control the mutation operation. The convergence property of the proposed IPSO is analyzed using standard results from the dynamic system theory and guidelines for proper algorithm parameter selection are derived. A new adaptive strategy for choosing parameters is also proposed to assure convergence of IPSO method. The proposed IPSO algorithm is also extended to handle mixed variables, such as transformer taps and the reactive power source installation, using a simple scheme. The IPSO applied for optimal power system reactive power dispatch is evaluated on an IEEE 30-bus power system and a practical 118-bus power system in which the control of bus voltages, tap position of transformers and reactive power sources are involved to minimize the transmission loss of the power system. Simulation results demonstrate that the proposed approach is superior to current methods for finding the best solution, in terms of both solution quality and algorithm robustness.
Traffic Classification for the Detection of Anonymous Web Proxy Routing

There is an increasing need to be able to classify whether an incoming packet is from a legitimate originating IP address or has been modified through an intermediate proxy or node. Being able to verify the originating IP address allows a business (e.g. bank) to use geolocation services in order to then ascertain which geographical location that packet was sent from. This can then feed into the system intrusion system or backend fraud alert mechanisms. The web however is going 'dark'. There is a noticeable uptake in the amount of encrypted data and third party anonymous traffic proxies which aim to mask the try location and IP address of a web request. We present here a system which identifies the characteristics or signatures whenever a user is using a web proxy by developing a Detection System that records packets and analyses them looking for identifying patterns of web proxies.
De l'étiquetage syntaxique pour les grammaires catégorielles de dépendances à l'analyse par transition dans le domaine de l'analyse en dépendances non-projective. (From syntactic tagging for categorial dependency grammars to transition-based parsing in the domain of non-projective dependency parsing

Cette these prend place dans le domaine de l’analyse syntaxique en dependances. D’une part nous etudions l’impact d’une methode statistique d’etiquetage syntaxique sur un analyseur base sur les grammaires categorielles de dependances. Nous proposons en ce sens un processus complet de pre-annotation comprenant la segmentation des phrases en mots (incluant les mots composes), l’etiquetage grammatical et syntaxique de ces mots et l’analyse en dependances de la phrase dans le but d’alleger le travail des annotateurs dans le cadre de la construction de corpus en dependances non-projectifs pour le francais. D’autre part, nous etudions egalement les methodes integralement dirigees par les donnees dans le domaine de l’analyse en dependances a travers l’adaptation d’un analyseur par transition a la representation en dependances des grammaires categorielles de dependances. Puis nous proposons une methode separant les etapes de prediction des dependances projectives et non-projectives dans le but d’ameliorer la prediction des dependances non-projectives. Nous montrons que cette methode est adaptable a n’importe quel corpus en dependances standard.
Multiple-scattering calculations of x-ray-absorption spectra.

A high-order multiple-scattering (MS) approach to the calculation of polarized x-ray-absorption spectra, which includes both x-ray-absorption fine structure and x-ray-absorption near-edge structure, is presented. Efficient calculations in arbitrary systems are carried out by using a curved-wave MS path formalism that ignores negligible paths, and has an energy-dependent self-energy and MS Debye-Waller factors. Embedded-atom background absorption calculations on an absolute energy scale are included. The theory is illustrated for metallic Cu, Cd, and Pt. For these cases the MS expansion is found to converge to within typical experimental accuracy, both to experiment and to full MS theories (e.g., band structure), by using only a few dozen important paths, which are primarily single-scattering, focusing, linear, and triangular.
Automatic Generation of Semantic Patterns using Techniques of Natural Language Processing

Within the discipline of natural language processing there are different approaches to analyze large amounts of text corpus. The identification patterns with semantic elements in a text let us classify and examine the corpus to facilitate interpretation and management of information through computers. This paper proposes the development of a software tool that generates index patterns automatically using various algorithms for lexical, syntactic and semantic analysis of text and integrates the results into other projects in the area of research and other ontological formats. The algorithms in the system implemented various types of analysis in the context of natural language processing, so they can identify grammatical categories and semantic characteristics of words, making up index patterns. The results obtained correspond to a pattern list sorted by frequency of occurrence and take into account intermediate optional elements, which determine its relevance and usefulness to other projects. The developed system proposes a model of generation and storage of patterns, and a control interface that allows the specification of parameters and running reports.
Multiple Roles of Vertebrate REV Genes in DNA Repair and Recombination

ABSTRACT In yeast, Rev1, Rev3, and Rev7 are involved in translesion synthesis over various kinds of DNA damage and spontaneous and UV-induced mutagenesis. Here, we disrupted Rev1, Rev3, and Rev7 in the chicken B-lymphocyte line DT40. REV1− / − REV3 − / − REV7 − / − cells showed spontaneous cell death, chromosomal instability/fragility, and hypersensitivity to various genotoxic treatments as observed in each of the single mutants. Surprisingly, the triple-knockout cells showed a suppressed level of sister chromatid exchanges (SCEs), which may reflect postreplication repair events mediated by homologous recombination, while each single mutant showed an elevated SCE level. Furthermore, REV1 − / − cells as well as triple mutants showed a decreased level of immunoglobulin gene conversion, suggesting participation of Rev1 in a recombination-based pathway. The present study gives us a new insight into cooperative function of three Rev molecules and the Polζ (Rev3-Rev7)-independent role of Rev1 in vertebrate cells.