Miracle-dz/UniFAR-FTUs huggingface dataset:
Grouping of Baikal omul Coregonus autumnalis migratorius Georgi within the C. lavaretus complex confirmed by using a nuclear DNA marker

Previous studies of the mtDNA cytochrome b gene and control region indicated that the Baikal omul was closely related to the Baikal whitefishes, but not to the Arctic cisco, Coregonus autumnalis Pallas, its closest taxonomic relative. Moreover, extremely high mtDNA similarity between Baikal omul and Baikal lacustrine whitefish, C. lavaretus baicalensis (Dyb.), was revealed. Direct sequencing of PCR-amplified DNA of the first internal transcribed spacer of ribosomal DNA (rDNA ITS1) of five taxa was carried out using previously designed primers to determine the position of the species within the Coregonidae: two ciscoes including the Arctic cisco, C. autumnalis Pallas, and the Irish pollan, C. pollan Thompson; and three of Lake Baikal's coregonids including Baikal omul, C. autumnalis migratorius Georgi, Baikal lacustrine whitefish, C. lavaretus baicalensis Dybovsky, and Baikal pidschian, C. lavaretus pidschian Pallas. The study showed again that Baikal omul grouped within the C. lavaretus complex. The trees that were obtained correlated with our previous results based on mtDNA analysis. We conclude that Baikal omul is one of many representatives of the C. lavaretus complex.
Initial Efforts to Document RNA in Vertebrate Model Axons

Periaxoplasmic ribosomal plaques (PARPs) are systematically recurring ribosome-containing structural domains located in the F-actin-rich periphery of axoplasm in myelinated fibers. In contrast, endoaxoplasmic ribosomal plaques (EARPs) are small, oval-shaped ribosomal aggregate structures randomly dispersed within the axoplasm of unmyelinated squid giant axons. Ribosomes are attached to a superficial plaque-like structural matrix, which “caps” the domain at the outer cortical margin and appears fragmented in subcortical axoplasm. As such, the matrix represents a novel hallmark of PARP domains. Molecular markers concentrated in PARP domains include b-actin mRNA, ZBP-1, SRP54, myosin Va and kinesin II molecular motor proteins. Rapid axoplasmic transport of microinjected heterologous radiolabeled BC1 RNA to putative PARP domains, mediated pari passu by microtubuleand F-actin-dependent systems, suggests that translation machinery, anchored by the matrix could provide targeted destinations for RNA trafficking. As distributed local centers of protein synthesis along axons, PARPs are likely to share modes of expression in common with other translational subdomains in neurons.
Variation of Moho Depth across Bangong-Nujiang Suture in Central Tibet—Results from Deep Seismic Reflection Data

There is a long-term dispute at Moho depth across the Bangong-Nujiang suture (BNS). Due to the complicated and changeable seismic geological condition, it is not easy to acquire images of the reflective Moho in central Tibet. In the support of the SinoProbe project, a series of deep seismic reflection profiles were conducted to image Moho structure across the BNS and the Qiangtang terrane. These profiles extend from the northern Lhasa terrane to the Qiangtang terrane crossing the BNS. Both shot gathers and migration data show clear Moho images beneath the BNS. The Moho depth varies from 75.1 km (~24 s TWT) beneath the northmost Lhasa terrane to 68.9 km (~22 s TWT) beneath southmost Qiangtang terrane, and rises smoothly to 62.6 km (~20 s TWT ) at ~28 km north of the BNS beneath the Qiangtang terrane. We speculate that the Moho appears a 6.2 km sharp offset across the BNS and becomes ~12.5 km shallower from the northmost Lhasa terrane to the south Qiangtang terrane at ~28 km north of the BNS. The viewpoint of Moho depth across the BNS based on deep seismic reflection data is inconsistent with the previous 20 km offset.
The Niederreiter cryptosystem and Quasi-Cyclic codes

McEliece and Niederreiter cryptosystems are robust and versatile cryptosystems. These cryptosystems work with any linear error-correcting codes. They are popular these days because they can be quantum-secure. In this paper, we study the Niederreiter cryptosystem using quasi-cyclic codes. We prove, if these quasi-cyclic codes satisfy certain conditions, the corresponding Niederreiter cryptosystem is resistant to the hidden subgroup problem using quantum Fourier sampling. Our proof requires the classification of finite simple groups.
The explicit form of expectation propagation for a simple statistical model

: We derive the explicit form of expectation propagation for approximate deterministic Bayesian inference in a simple statistical model. The model corresponds to a random sample from the Normal distribution. The explicit forms, and their derivation, allow a deeper understanding of the issues and challenges involved in practical implementation of expectation propagation for statistical analyses. No auxiliary approximations are used: we follow the expectation propagation prescription exactly. A simulation study shows expectation propagation to be more accurate than mean ﬁeld variational Bayes for larger sample sizes, but at the cost of considerably more algebraic and computational eﬀort.
Terms of Trade and Current Account Fluctuations: a Vector Autoregression Approach

This paper provides evidence on the Harberger-Laursen-Metzler (HLM) effect for the case of Peru. The HLM effect is the deterioration in the savings level of an economy due to a decline in their terms of trade for a given level of investment. This deterioration is caused by lower revenues which worsen the current account. We estimate VAR models that match up the following variables: terms of trade, export prices, import prices, current account, investment and saving. The results show that an unanticipated-permanent increase in the terms of trade (or export prices) improves the current account and saving rises. However, this effect disappears as investment grows faster than saving. On the other hand, an increase in the price of imports negatively affects the current account.
Altman Z-Score Model for Bankruptcy Forecasting of the Listed Lithuanian Agricultural Companies

Since development in 1968, Altman’s Z-score has been widely used to judge the risk of financial failure by companies in various countries, industries, and time-periods. The purpose of this paper is to apply Altman’s Z-score model for bankruptcy prediction on the three listed Lithuanian agricultural companies. Agribusiness is an important industry in Lithuania and recent trends of consolidation and long-term government subsidies make evaluation of financial health of such companies important not only for the owners, but for the other stakeholders as well. The study has found that the model correctly places companies into “safe” and “grey” zones, which gives initial information for the stakeholders. Further exploratory study into the financial and non-financial factors constituting Z-score could provide additional information for forecasting firm’s performance.
Gadus morhua

The role of recreational fisheries in the exploitation pressure on fish resources is increasingly recognized. This has led to the introduction of new harvest regulations for several European marine recreational fisheries. Such regulations have been shown to increase the practice of regulatory catch-and-release (C&R). Additionally, anglers have been shown to practice voluntary C&R due to various personal motivations. Access-point surveys in two study areas in Northern and Southern Norway found that marine angling tourists release more than 60% of their catch for several species due to regulatory and voluntary C&R. For Atlantic cod (Gadus morhua) alone, this corresponds to more than one million individuals released annually by angling tourists in Norway. A review of published, unpublished and grey literature on C&R for nine European marine recreational fisheries found that C&R is a common practice in many European countries. Among the studied European marine species caught by recreational anglers, the highest absolute release numbers were found for Atlantic cod. Impacts of C&R on Atlantic cod under best practice conditions, and the effects of different capture depths on barotrauma symptoms and post-release mortality of cod were investigated in a telemetry study and a containment study, respectively. The telemetry study showed that some cod show behavioral alterations after C&R, but can recover quickly if they are caught in shallow waters (<20 m) and properly handled before release. The containment study showed that even though cod develop several barotrauma symptoms depending on capture depth, short-term mortality due to barotrauma is negligible (assuming minimal predation) if cod submerge quickly and are otherwise not substantially injured. Based on these results and other studies, a framework for the development of best practice C&R guidelines for cod is presented. To ensure that the study findings are understood and adopted by fisheries managers and anglers, efficient communication is essential, which requires a combination of several communication channels, including scientific publications, the media and information flyers. Even though emergent animal welfare concerns could not be resolved, a better understanding of C&R impacts on cod through this thesis will hopefully contribute to improving recreational fishing practices, which subsequently may minimize sublethal C&R effects and lead to decreased post-release mortality of cod in the future.
asitologie , virologie rst description of a new uncultured purple sulfur bacterium lonizing marine mangrove sediment in the Caribbean : lochromatium-like PSB from Guadeloupe scription d ’ une bactérie sulfureuse pourpre non cultivable colonisant sédiments des mangroves marine dans

Here, we report the first description of a marine purple sulfur bacterium (PSB) from sulfide-rich sediments of a marine mangrove in the Caribbean. TEM shows that this new isolate contains intracytoplasmic vesicular membrane systems (containing bacteriochlorophyll a) and larger internal sulfur granules, confirmed by EDXS analyses performed using ESEM. The sulfur distribution and mapping obtained for this PSB strain has allowed us to conclude that elemental sulfur is formed as an intermediate oxidation product and stored intracellularly. SEM shows that the bacterial cells are ovoid and extremely motile via lophotrichous flagella. Phylogenetic characterization, based on the analysis of 16S rDNA and functional gene pufM sequences, demonstrate that this strain belongs to the Chromatiaceae and may be a representative of a new species of the genus Halochromatium. Thus, reduced sediments of marine mangrove represent a sulfide-rich environment that sustains the development ofChromatiaceae, in addition to sulfuroxidizing bacteria and cyanobacteria, as previously reported. C 2018 Published by Elsevier Masson SAS on behalf of Académie des sciences. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/
Evaluating The Short-Term Excess-Return: A New Methodology

In this paper, a new methodology for evaluating short-term excess return is suggested. The intuition behind this methodology is derived from the forward rate calculation and it does not require that the betas remain constant over time. The new methodology is compared with other short-term estimators and substantial score and ranking differences are found. In addition, the short-term estimators are analyzed based onaspects of expected value and variance and the conclusion is that the new methodology is the better one. Simulation tests support this result. Finally, the new methodology also yields performance scores and rankings that are the most consistent with their long-term counterparts.
When Gaussian Processes Meet Combinatorial Bandits : GCB

Combinatorial bandits (CMAB) are a generalization of the well-known Multi-Armed Bandit framework, in which the learner chooses, at each round, a subset of the available arms that satisfies some known constraints. The learner observes the payoffs of each chosen arm and aims at maximizing the cumulative reward. We study, for the first time, CMAB settings with some form of correlation over the arms expected rewards. The arm correlation is crucial to allow algorithms to be effective when the space of the arms is large. In the present paper, we propose a bandit algorithm, namely Gaussian Combinatorial Bandit (GCB), designed for settings in which the arms are partitioned in subsets, and the payoff functions of the arms of each subset are jointly distributed as a Gaussian Process (GP). We provide two different variations of our algorithm (frequentist and Bayesian) that, under mild assumptions, their worst-case regret is Õ(C √ N), where C is the number of subsets of arms whose payoffs are correlated and N is the number of rounds.
AIM 2019 Challenge on Constrained Super-Resolution: Methods and Results

This paper reviews the AIM 2019 challenge on constrained example-based single image super-resolution with focus on proposed solutions and results. The challenge had 3 tracks. Taking the three main aspects (i.e., number of parameters, inference/running time, fidelity (PSNR)) of MSRResNet as the baseline, Track 1 aims to reduce the amount of parameters while being constrained to maintain or improve the running time and the PSNR result, Tracks 2 and 3 aim to optimize running time and PSNR result with constrain of the other two aspects, respectively. Each track had an average of 64 registered participants, and 12 teams submitted the final results. They gauge the state-of-the-art in single image super-resolution.
Forecast of Employment in Switzerland: The Macroeconomic View

Switzerland is a unique in its own way country which, although being located in the heart of Europe, is an independent state and non-European Union (EU) member. Its political structure and future development direction is very different from the rest of the Europe. Swiss economy, in comparison with others neighboring EU countries, is much stronger. Being inspired by highly competitive and successful economic performance of Switzerland, the aim of the present study is to conduct a macroeconomic analysis via observing and forecasting the employment/unemployment rates in Switzerland. Employing time series analysis and econometric calculations own forecast will be collated with the forecast published by the Federal Statistical Office of Switzerland. The practical importance of the obtained results will be, as expected, manifested in finding possible ways how to fight unemployment and achieve at least 70% employment rate in the Czech Republic.
DEVELOPMENT OF PROCESS CONTROL PLANS FOR QUALITY ASSURANCE SPECIFICATIONS

Statistically based quality assurance specifications, such as the restricted performance bituminous specification of the Pennsylvania Department of Transportation, provide a clear delineation between the acceptance responsibilities and the process control responsibilities of the highway agency and the contractor or material supplier. They also usually require that a process control plan be submitted for approval before the commencement of work. Because the available technical literature has favored the acceptance phase, there is currently little guidance available to these parties when they prepare such a plan. The need for such guidance is illustrated by presenting the two extreme approaches that may be taken to meet the requirements of the Pennsylvania Department of Transportation. The first case illustrates the "ideal" process control plan that can be developed if a literal interpretation of the specification is made. This plan clearly requires excessive documentation. It is contrasted with the process control plans currently being submitted to the Pennsylvania Department of Transportation, which do not provide enough detail to allow a determination of adequacy. A need is thus indicated for the industry to develop technical information that provides guidance in the development of plans that are somewhere between these extremes. /Authors/
EFFECTS OF FUNGICIDES ON ENDOPHYTIC FUNGI AND PHOTOSYNTHESIS IN SEEDLINGS OF A TROPICAL TREE, Guarea guidonia (Meliaceae)

Endophytes are microorganisms that live within healthy plant tissues, and include fungi and bacteria. They can be mutualists, comensals or even latent pathogens. Presence of these endosymbionts may affect host physiology, for example by consuming products of photosynthesis (endophytes are heterotrophs) or producing toxic metabolites. In this work two fungicides were used to eliminate fungal endophytes from seedlings of Guarea guidonia. Lightsaturated photosynthesis (Amax) was measured in endophytefree plants and compared with control plants. Each fungicide killed different fungal endosymbionts. Phomopsis was more susceptible to benomyl while Colletotrichum was more susceptible to propiconazole. Although suggestive, values of Amax were not significantly different for each treatment compared with control plants. No prediction can be made at this point about the final outcome of a given plantendophytic fungi interaction.
Atmospheric ionization by high‐fluence, hard‐spectrum solar proton events and their probable appearance in the ice core archive

Solar energetic particles ionize the atmosphere, leading to production of nitrogen oxides. It has been suggested that some such events are visible as layers of nitrate in ice cores, yielding archives of energetic, high‐fluence solar proton events (SPEs). This has been controversial, due to slowness of transport for these species down from the upper stratosphere; past numerical simulations based on an analytic calculation have shown very little ionization below the midstratosphere. These simulations suffer from deficiencies: they consider only soft SPEs and narrow energy ranges; spectral fits are poorly chosen; and with few exceptions secondary particles in air showers are ignored. Using improved simulations that follow development of the proton‐induced air shower, we find consistency with recent experiments showing substantial excess ionization down to 5 km. We compute nitrate available from the 23 February 1956 SPE, which had a high‐fluence, hard‐spectrum, and well‐resolved associated nitrate peak in a Greenland ice core. For the first time, we find that this event can account for ice core data with timely (~2 months) transport downward between 46 km and the surface, thus indicating an archive of high‐fluence, hard‐spectrum SPEs covering the last several millennia. We discuss interpretations of this result, as well as the lack of a clearly defined nitrate spike associated with the soft‐spectrum 3–4 August 1972 SPE. We suggest that hard‐spectrum SPEs, especially in the 6 months of polar winter, are detectable in ice cores and that more work needs to be done to investigate this.
Alignment of Point Clouds for Comparison of Infrastructures in Civil Engineering on Quality Control in Metrology

For 3D point cloud registration, Go-ICP [Yang et al., 2016] has been shown to obtain the global optimal solution for a pair composed of a model point cloud and a data point cloud. Go-ICP mostly has been investigated only on standard sets of point clouds. In this paper, we demonstrate the remarkable efficacy of Go-ICP for the alignment of very complex large-scale point clouds to their corresponding deformed CAD models. In particular, given two distinct sets of point clouds taken from the exterior and the interior of a building, experiments demonstrate that Go-ICP is able to successfully align both of these sets to the point cloud of the CAD model of the whole building (both exterior and interior information included). With the experimentation presented in this paper, we demonstrate that Go-ICP can achieve excellent alignment results and that this approach can be deployed in applications aiming at comparing CAD models of a building ("as designed" model) to the point cloud of the actual building ("as-built" model). Experiments also demonstrate the efficacy of Go-ICP to align a deformed copy of a man-made object to the original object in quality control applications.
AWARD NUMBER: W81XWH-14-1-0237 TITLE: Targeting histone abnormality in triple negative breast cancer PRINCIPAL INVESTIGATOR:

Flavin-dependent histone demethylases govern histone H3K4 methylation and act as important chromatin modulators that are extensively involved in regulation of DNA replication, gene transcription, DNA repair, and heterochromatin gene silencing. While the activities of lysine-specific demethylase 1 (LSD1/KDM1A) in facilitating breast cancer progression have been well characterized, the roles of its homolog LSD2 (KDM1B) in breast oncogenesis are relatively less understood. In this study, we showed that LSD2 protein level was significantly elevated in malignant breast cell lines compared with normal breast epithelial cell line. TCGAOncomine database showed that LSD2 expression is significantly higher in basal-like breast tumors compared to other breast cancer subtypes or normal breast tissue. Overexpression of LSD2 in MDA-MB-231 cells significantly altered the expression of key important epigenetic modifiers such as LSD1, HDAC1/2, and DNMT3B; promoted cellular proliferation; and augmented colony formation in soft agar; while attenuating motility and invasion. Conversely, siRNA-mediated depletion of endogenous LSD2 hindered growth of multiple breast cancer cell lines while shRNA-mediated LSD2 depletion augmented motility and invasion. Moreover, LSD2 overexpression in MDA-MB-231 cells facilitated mammosphere formation, enriched the subpopulation of CD49f+/EpCAMand ALDHhigh, and induced the expression of pluripotent stem cell markers, NANOG and SOX2. In xenograft studies using immune-compromised mice, LSD2-overexpressing MDA-MB-231 cells displayed accelerated tumor growth but significantly fewer lung metastases than controls. Taken together, our findings provide novel insights into the critical and multifaceted roles of LSD2 in the regulation of breast cancer progression and cancer stem cell enrichment.
mproved kinetics from ion advection through overlapping electric double layers n nano-porous electrodes saac

A novel device architecture is presented for laminar flow fuel cell by introducing an ion advection flux within the electric double layer (EDL). Typically advection in the EDL is negligible because the near wall electrolyte velocity is zero. However, by using nano-pores, a non-negligible ion advection flux can be developed in the charged regions of the EDL. In this article we study how advection in the EDL affects the kinetic performance of electrochemical cells. To accomplish this we use a laminar flow fuel cell model based on the Poisson–Nernst–Planck and Frumkin–Butler–Volmer equations. The model contains nonlinear physics with very disparate length scales due to the complex 3-dimensional nature of the nanoporous device. To account for these difficulties, the full mathematical model is solved numerically using a novel numerical algorithm developed based on domain decomposition method. The presented algorithm allows the simulation of complex near wall electrode effects, such as overlapping double layers in a nanolectrolyte advection pore, in the context of a complete device, which would have been numerically prohibitive otherwise. The presence of an advection flux through nano-pores on the order of the EDL width yields some novel phenomena that affect the structure of electrode–electrolyte interface. The most surprising result is the development of a region of zero charge at the electrodes in the upstream regions of longer nano-pores. We also show that electrolyte advection within the EDL can be used to enhance the kinetic performance of electrodes in electrochemical cells.