Miracle-dz/UniFAR-FTUs huggingface dataset:
Multiresolution Mesh Reconstruction from Noisy 3D Point Sets

We augment the tensor voting framework with a data-driven multiscale scheme for reconstructing a multiresolution mesh from a noisy 3D point set. The augmentations are effective, automatic but very simple, consisting of surface saliency inference, scale segmentation, and data normalization. These data analysis steps enable tensor voting to operate at a single scale in each normalized data segment, by decoupling scale and smoothness control. They also guide tensor voting to reconstruct at optimal resolutions subject to the sampling theory. The output is a multiresolution mesh that captures large and small scale features faithfully, without using the maximum resolution everywhere in the domain. The augmented methodology is very robust in the presence of noisy and irregular samples, and non-trivial holes that cover large areas involving multiple-scale features
AR interior designer: Automatic furniture arrangement using spatial and functional relationships

In big cities the population is increasing that leads to smaller flats. It is hard to pick a furniture that perfectly suits to the available space at home. Therefore it requires people to measure the available space by hands, which is inefficient. In this paper, we propose an Augmented Reality (AR) interior design tool. The furniture reseller can make virtual 3D furniture available, and then via AR the virtual furniture are rendered in the real scene of our home space. A depth camera is used to measure the size of available space (in terms of supporting surfaces) for new furniture, such as the floor and desk/table surfaces. By the meantime, the obstacles are detected and marked unavailable for furniture placement. In a glance, the user can quickly determine whether that furniture is suitable or fit enough to the available space. Sometimes, the user may buy two or more furniture. Our another contribution is recommending an optimum arrangement of the furniture by determining the spatial and functional relationship between different pieces of furniture. Some challenging cases of furniture placement are shown.
Teaching elementary school students new method of music performance with Leap Motion

As the world continue to embrace motion recognition technology in recent years, it had also open up a new method for performing and learning music with motion recognition devices. In 2013, Leap Motion was released. It is a programmable motion recognition device, ticking the requirement needed by the Author to design a new software and application for music education. This research focus on the the process of creating a new software that will use the Leap Motion technology for music education class at elementary school. The research is meant to develop alternative ways in teaching music and performing for children, not to replace the traditional teaching method. The paper will talk about the whole experience of designing, implementing, and testing the usage of Leap Motion for music education. The research consist of two phase. The first phase is the music software design. It had 2 main program. The first program is the performance application, students can use both of their hands to perform music through the software, limited only to monophonic melody. The right hand will be positioned to control the pitch, on a one octave diatonic scale. The left hand will be positioned to control the note on and note off. Through the combination of these hand position, the student will be able to play one note at a time, a mono sine wave sound. The second program is the game application, student can practice their hand movement and carry out their music practice with this music application that's designed to mimic note scrolling music video games like the one found on commercial video games like Rock Band or Guitar Hero. A series of notes can be seen on the software user interface and they can practice to position their hand at the right moment to perform the right melody of the music piece. This music software is aimed toward first and second grade of elementary school student as it can be devised as a tool to help the student to learn melody and rhythm in music. The second phase of the research is a field study to measure the effectiveness of teaching this new method of music education through survey. The survey conclude that the there's still a long way to go to create an ideal motion recognition music based application. Through this survey we have collected data that consist of the the positives and negative opinion on the students experience with the software.
A Kinetic Model for Tribological Surface Transformations Occuring on the Railroads: Irreversible Near-Surface Metallurgical Transformations

During the manufacturing processes or the operational phases, some materials are liable to undergo metallurgical phenomena known as irreversible solid-solid phase transformations or Tribological Surface Transformations (TSTs). The treads of several rails in the French railroad network have been affected by TSTs. The kinetic model presented in this paper describes the initiation of TSTs and their development near the rail surface.
The Tuberous Sclerosis 2000 Study: presentation, initial assessments and implications for diagnosis and management

Aims The Tuberous Sclerosis 2000 Study is the first comprehensive longitudinal study of tuberous sclerosis (TS) and aims to identify factors that determine prognosis. Mode of presentation and findings at initial assessments are reported here. Methods Children aged 0–16 years newly diagnosed with TS in the UK were evaluated. Results 125 children with TS were studied. 114 (91%) met clinical criteria for a definite diagnosis and the remaining 11 (9%) had pathogenic TSC1 or TSC2 mutations. In families with a definite clinical diagnosis, the detection rate for pathogenic mutations was 89%. 21 cases (17%) were identified prenatally, usually with abnormalities found at routine antenatal ultrasound examination. 30 cases (24%) presented before developing seizures and in 10 of these without a definite diagnosis at onset of seizures, genetic testing could have confirmed TS. 77 cases (62%) presented with seizures. Median age at recruitment assessment was 2.7 years (range: 4 weeks–18 years). Dermatological features of TS were present in 81%. The detection rate of TS abnormalities was 20/107 (19%) for renal ultrasound including three cases with polycystic kidney disease, 51/88 (58%) for echocardiography, 29/35 (83%) for cranial CT and 95/104 (91%) for cranial MRI. 91% of cases had epilepsy and 65% had intellectual disability (IQ<70). Conclusions Genetic testing can be valuable in confirming the diagnosis. Increasing numbers of cases present prenatally or in early infancy, before onset of seizures, raising important questions about whether these children should have EEG monitoring and concerning the criteria for starting anticonvulsant therapy.
Screening for Illicit Drug Use in Drug Development Studies

Increased attention is being focused on illicit drug use in the general public, but little information exists on the pattern of illicit drug use for volunteers for Phase I. The Upjohn Research Clinics, Kalamazoo, MI, conducted a retrospective survey of the incidence of positive drug screens found in the subject population of Phase I studies initiated between 1987 and 1989. Research subjects were recruited from a pool of 8,052 males and females over the age of 17 years. The use of illicit drugs was recorded for 621 (7.7%) of these subjects. There was a total of 99 studies of which only 57 (58%) actually required drug screens. Of these studies with drug screens, 17,033 tests were completed with 377 tests (1.4%) in 291 individual subjects reporting positive for illicit drugs including cannabinoids, amphetamines, cocaine, opiates, benzodiazepines, and barbiturates. Most but not all studies requested screening for all six drugs listed. The drugs encountered in decreasing order of frequency (total number of requested individual tests; number and percent of positive tests) were: cannabinoids (n = 2,921; 168, 5.8%), amphetamines (n = 3,066; 110, 3.6%), barbiturates (n = 3,039; 35, 1.2%), cocaine (n = 3,176; 36, 1.1%), opiates (n = 1,861; 18, 1.0%) and benzodiazepines (n = 2,970, 10, 0.3%). The number of overall research studies and the percent of studies requiring drug screens has remained relatively constant over the last three years (1987, 35, 57%; 1988, 35, 60%; 1989, 29, 59%). Conclusion: The frequency and pattern of illicit drug use mirrors the general population. Recommendations are made as to how to more effectively screen for polysubstance use (eg, alcohol consumption plus illicit drugs) or how to monitor illicit drug use while subjects are participating in clinical trials.
Clinical Acceptability of two Self-Etch Adhesive Resins for the Bonding of Orthodontic Brackets to Enamel

Objective To determine whether two self-adhesive resin cements, Clearfil SA and RelyX, can be used to successfully bond orthodontic brackets to enamel. Materials and methods Seventy extracted premolars were custom mounted, cleaned and randomly divided into three groups. In group 1 (control), orthodontic brackets were bonded to 25 premolars using the Transbond Plus and Transbond XT two step adhesive systerm adhesive. In group 2, brackets were bonded to 25 premolars using Clearfil SA. In group 3, brackets were bonded to 20 premolars using RelyX. The brackets were debonded using a universal testing machine and shear bond strengths recorded. After debonding, each tooth was examined under 20× magnification to evaluate the residual adhesive remaining. An ANOVA with Duncan's Multiple Range Test was used to determine whether there were significant differences in shear bond strength between the groups. A Kruskal–Wallis Test and a Bonferroni multiple comparison procedure were used to compare the bond failure modes (adhesive remnant index scores) between the groups. Results The mean shear bond strengths for the brackets bonded using Clearfil SA and RelyX were 5·930±1·840 and 3·334±1·953 MPa, respectively. Both were significantly lower than that for the brackets bonded using Transbond (7·875±3·611 MPa). Both self-etch adhesive resin cement groups showed a greater incidence of bracket failure at the enamel/adhesive interface while the Transbond group showed a higher incidence at the bracket/adhesive interface. Conclusions The shear bond strengths of the self-etch adhesive resin cements may be inadequate to successfully bond orthodontic brackets to enamel.
Handling anticipated exceptions in clinical care: investigating clinician use of 'exit strategies' in an electronic health records system

Unpredictable yet frequently occurring exception situations pervade clinical care. Handling them properly often requires aberrant actions temporarily departing from normal practice. In this study, the authors investigated several exception-handling procedures provided in an electronic health records system for facilitating clinical documentation, which the authors refer to as 'data entry exit strategies. ' Through a longitudinal analysis of computer-recorded usage data, the authors found that (1) utilization of the exit strategies was not affected by postimplementation system maturity or patient visit volume, suggesting clinicians' needs to 'exit' unwanted situations are persistent; and (2) clinician type and gender are strong predictors of exit-strategy usage. Drilldown analyses further revealed that the exit strategies were judiciously used and enabled actions that would be otherwise difficult or impossible. However, many data entries recorded via them could have been 'properly' documented, yet were not, and a considerable proportion containing temporary or incomplete information was never subsequently amended. These findings may have significant implications for the design of safer and more user-friendly point-of-care information systems for healthcare.
Orthodontic Scanners: What's Available?

The popularity and availability of virtual technology in orthodontics for the replacement of hard-copy records with electronic records is growing rapidly, with a move towards a ‘digital’ patient for diagnosis, treatment planning, monitoring of treatment progress and outcome. As part of this ongoing development, three-dimensional digital models of the dental arches have the potential to replace traditional plaster models and their associated limitations for treatment planning, appliance construction and simulated treatment outcomes. This article provides the reader with a summary of the currently available benchtop model scanners and intraoral scanners. It is likely that this technology will become increasingly common-place within the orthodontic profession over the next decade.
Application of conjugate gradient methods in MMSE equalization for the forward link of DS-CDMA

The chip-level MMSE estimate of the (multiuser) synchronous sum signal transmitted by the base-station, followed by a correlate and sum, has been shown to perform very well in the CDMA forward link using orthogonal channel codes. In this paper, adaptive chip-level MMSE estimation based on the conjugate gradient (CG) algorithm is presented. Our simulations show that, adaptive CG using the pilot channel for training can achieve excellent convergence at a moderate computational cost.
Immunity to hepatitis B vaccine in Tanzanian under-5 children

Abstract Background: Hepatitis B vaccine was introduced in Tanzania in 2002 and is administered as DPT-hepatitis B at 4, 8 and 12 weeks of life. Aim: To determine immunity to hepatitis B virus in children under 5 years attending reproductive and child health (RCH) clinics. Methods: A cross-sectional, health facility-based study was conducted between July and December 2007 at Temeke, Amana and Mwananyamala municipal hospitals in Dar es Salaam, Tanzania. Children under 5 years who had received DPT-HB vaccine as evidenced by RCH card number 1 were included. Blood samples were collected to determine hepatitis B surface antigen (HBsAg) and antibodies to hepatitis B surface antigen (anti-HBs) and hepatitis B core antigen (Anti-HBc). An anti-HBs level of ≥10 mIU/ml is regarded as protective. Nutritional and HIV status were also determined. Results: A total of 296 children under 5 years vaccinated with DPT-HB were recruited, 153 (51.7%) of whom were male. Altogether, 205 (69.3%) children had anti-HBs levels ≥10 mIU/ml. The number of DPT-HB vaccine doses, time interval since last DPT-HB dose and HIV status were significant predictors of anti-HBs levels. Five children (1.7%) were positive for HBsAg, suggesting possible vertical transmission. No child had anti-HBc antibodies. Conclusion: More than two-thirds of children under 5 years had protective anti-HBs levels. A change in the hepatitis B immunisation schedule to include a dose immediately after birth should improve immunity.
Utilization of a multimedia PACS workstation for surgical planning of epilepsy

Surgical treatment of temporal lobe epilepsy requires the localization of the epileptogenic zone for surgical resection. Currently, clinicians utilize electroencephalography, various neuroimaging modalities, and psychological tests together to determine the location of this zone. We investigate how a multimedia neuroimaging workstation built on top of the UCSF Picture Archiving and Communication System can be used to aid surgical planning of epilepsy and related brain diseases. This usage demonstrates the ability of the workstation to retrieve image and textural data from PACS and other image sources, register multimodality images, visualize and render 3D data sets, analyze images, generate new image and text data from the analysis, and organize all data in a relational database management system.
Interaction Recognition Using Sparse Portraits

We propose a method for classifying actions involving people interacting with objects. Our method combines motion and appearance information into a unified framework. Here, we explore the video's sparse component as provided by robust principal-component analysis for the extraction of motion information in the form of trajectories. While we use motion as the main clue for classification, we also incorporate implicit object information into the classification process. Here, object information is represented by the probability of the object with which the person is interacting. These probabilities are learned using probabilistic Latent Semantic Analysis (pLSA). We test our classification method on a publicly available dataset, and provide a comparison with some related work. Classification results obtained by our method are promising.
Conversation repair: Ecological validity of outcome measures in acquired hearing impairment

Abstract Objective Everyday conversation is the most widely reported difficulty arising from adult acquired hearing impairment (HI), yet no clinical method currently exists by which direct observation of conversational ability can be measured. This review of recent research argues that specific patterns of conversation repair arise in interaction involving adults who have acquired HI and that they may be of utility in assessing the outcome of intervention. Methods This brief review paper presents a summary of data on the conduct of repair in free and unstructured conversations between HI adults and their frequent communication partners using Conversation Analysis as the guiding theory and analytic method. Results Results indicate that certain types of repair are influenced by one participant in the conversation having an acquired hearing impairment. Further, these patterns of repair behaviour are resolved in concert by the participants in the conversation. Discussion Patterns of repair behaviour may be used as criterion variables in assessing the need for and outcome of audiological intervention, including implantation, hearing aid fitting and/or conversation-based therapy. Previous research has shown that these measures are both consistent across time in the absence of intervention and that they are sensitive to intervention. Conclusion These findings support the potential for conversationally-oriented therapy models of assessment and intervention and suggest a framework by which clinical tasks might be analysed with respect to their conversation ‘reality’. This initial evidence needs to be supported by investigations across larger samples of adults with acquired hearing impairment.
Integration of health and social care – what can Wales learn … and contribute?

Purpose – This paper aims to present a review on health and social care service integration, drawing on experience from the United Kingdom, Europe and Canada.Design/methodology/approach – A review of the literature was undertaken and critical summaries of the findings are presented.Findings – It seems no country can put forward a universal set of principles that are applicable in all settings.Practical implications – Each country has their own challenges, so perhaps this encourages Welsh professionals to learn from their own experience.Originality/value – This paper adds value by drawing together the literature and providing a contribution from Wales.
An Evaluation of the Faster STORM Method for Super-resolution Microscopy

Development of new stochastic super-resolution methods together with fluorescence microscopy imaging enables visualization of biological processes at increasing spatial and temporal resolution. Quantitative evaluation of such imaging experiments call for computational analysis methods that localize the signals with high precision and recall. Furthermore, it is desirable that the methods are fast and possible to parallelize so that the ever increasing amounts of collected data can be handled in an efficient way. We herein address signal detection in super-resolution microscopy by approaches based on compressed sensing. We describe how a previously published approach can be parallelized, reducing processing time at least four times. We also evaluate the effect of a greedy optimization approach on signal recovery at high noise and molecule density. Furthermore, our evaluation reveals how previously published compressed sensing algorithms have a performance that degrades to that of a random signal detector at high molecule density. Finally, we show the approximation of the imaging system's point spread function affects recall and precision of signal detection, illustrating the importance of parameter optimization. We evaluate the methods on synthetic data with varying signal to noise ratio and increasing molecular density, and visualize performance on real super-resolution microscopy data from a time-lapse sequence of living cells.
Reverberation negatively impacts musical sound quality for cochlear implant users

Abstract Objective Satisfactory musical sound quality remains a challenge for many cochlear implant (CI) users. In particular, questionnaires completed by CI users suggest that reverberation due to room acoustics can negatively impact their music listening experience. The objective of this study was to more specifically characterize of the effect of reverberation on musical sound quality in CI users, normal hearing (NH) non-musicians, and NH musicians using a previously designed assessment method, called Cochlear Implant-MUltiple Stimulus with Hidden Reference and Anchor (CI-MUSHRA). Methods In this method, listeners were randomly presented with an anechoic musical segment and five-versions of this segment in which increasing amounts of reverberation were artificially added. Participants listened to the six reverberation versions and provided sound quality ratings between 0 (very poor) and 100 (excellent). Results Results demonstrated that on average CI users and NH non-musicians preferred the sound quality of anechoic versions to more reverberant versions. In comparison, NH musicians could be delineated into those who preferred the sound quality of anechoic pieces and those who preferred pieces with some reverberation. Discussion/Conclusion This is the first study, to our knowledge, to objectively compare the effects of reverberation on musical sound quality ratings in CI users. These results suggest that musical sound quality for CI users can be improved by non-reverberant listening conditions and musical stimuli in which reverberation is removed.
Genome-wide association study identifies GIMAP as a novel susceptibility locus for Behçet's disease

Objectives To identify non-major histocompatibility complex susceptible genes that might contribute to Behçet's disease (BD). Methods We performed a genome-wide association study using DNA samples from a Korean population consisting of 379 BD patients and 800 controls. A replication study was performed in a Japanese population (363 BD patients and 272 controls). To evaluate the functional implication of the target single nucleotide polymorphisms (SNP), gene expression levels in peripheral T cells, allele-specific modulation of promoter activity and biological effect of mRNA knockdown were investigated. Results We found a novel association of BD to the GIMAP locus, mapped to chromosome 7q36.1 (rs1608157, p=6.01×10−8 in a minor allele dominant model; rs11769828, allele based p=1.60×10−6). A fine mapping study identified an association with four additional SNP: rs1522596 (OR=1.45, p=7.70×10−6) in GIMAP4; rs10266069 (OR=1.32, p=2.67×10−4) and rs10256482 (OR=1.27, p=5.27×10−4) in GIMAP2; and rs2286900 (OR=1.61, p=3.53×10−5) in GIMAP1 areas. Replication study using DNA samples from the Japanese population validated the significant association between BD and the GIMAP locus. The GIMAP4 promoter construct plasmid with the minor allele of rs1608157 displayed significantly lower activity than one with the major allele. Moreover, CD4 T cells from BD patients showed a lower level of GIMAP4 mRNA, and GIMAP4 knockdown was protective against Fas-mediated apoptosis. Conclusions These results suggest that a GIMAP cluster is a novel susceptibility locus for BD, which is involved in T-cell survival, and T-cell aberration can contribute to the development of BD.