Miracle-dz/UniFAR-FTUs huggingface dataset:
Rapid conversion of cyclohexenone, cyclohexanone and cyclohexanol to ε-caprolactone by whole cells of Geotrichum candidum CCT 1205

Abstract ɛ-Caprolactone (ɛ-CL) was obtained with excellent conversion and short reaction times from the substrates cyclohexenone, cyclohexanone and cyclohexanol using whole cells of Brazilian Geotrichum candidum (CCT 1205). The reactions were monitored over time by gas chromatography, and the intermediates of the one-pot cascade biotransformation involving reductions of C=C and C=O bonds as well as the Baeyer–Villiger oxidation were identified and quantified. The Baeyer–Villiger monooxygenase (BVMO) enzyme was predominant, and all three substrates were completely converted into ɛ-CL. Furthermore, the whole cells of Geotrichum candidum were recycled and reutilized in the biotransformation of cyclohexanone, producing ɛ-CL at least six consecutive times without a significant loss of activity, reaction yields or product purity.
A Modified Topology of a High Efficiency Bidirectional Type DC–DC Converter by Synchronous Rectification

A modified Topology to acquire high efficiency of a bidirectional method of DC–DC converter of non-isolated approach is proposed. The modified circuit involves four numbers of switches with their body diodes, passive elements as two inductors as well as a capacitor and the circuit arrangements double boost converters to progress the voltage gain. The input current of the proposed topology divided amongst the two dissimilar values of inductors produces greater efficiency. In the step-down mode, an apparent lessening in voltage gain and also enhanced efficiency can be realized in the recommended system by expending a synchronous rectification. The modified topology shields the technique for presentation of easy control configurations and is used for truncated output voltage with a large current of energy storage systems in the renewable applications as well as hybrid energy source electric vehicle applications. The simulation of the projected structure has been conducted through MATLAB/Simulink software and has been corroborated through a 12 V/180 V, 200 Watts experimental prototype circuit.
Emergency nurse’s perceptions of hospital facility support and disaster preparedness

Disasters cause material losses, morbidity, and deaths. Support for the role of hospitals and health workers, especially nurses, is needed to reduce the number of victims in each disaster. Using a cross-sectional survey design, this study aims to analyze the relationship between nurse’s perceptions of hospital facility support and disaster preparedness. One hundred sixty seven respondents were selected using proportional random sampling. Disaster preparedness evaluation tool (DPET) was used to assess the participants’ readiness, and the Health Sector Self-Assessment Tool for Disaster Risk Reduction was used to assess nurse’s perceptions of hospital facility support. The final results of the analysis using the Spearman Rank test showed a significant correlation between hospital infrastructure support and emergency nurse’s preparedness in disaster preparedness with a p-value (0.00). The higher the nurse’s perceptions of hospital facility support, the higher their preparedness in disaster management is. Strengthening guidelines of disaster planning in hospitals, especially regarding the ability of hospitals to overcome the impacts of disasters, will provide optimal support for emergency nurses during a disaster crisis.
Status number for measuring genetic diversity

Genetic diversity is a key issue. To monitor and predict genetic diversity, measures are urgently needed. It is argued that half the inverse of the average coancestry in the breeding population is a suitable measure for describing the diversity status of a pedigreed population. We will call that the status (effective) number. The concept of status number and its characteristics are discussed in relation to other measures. It will be equal to the census number for unrelated non-inbred individuals. It can never be bigger than the census number and never smaller than 0.5. An algorithm to calculate status number for real materials is presented. Breeding populations were monitored for status number over 10 generations using predicative formulas and Monte Carlo simulations.
Development of Selenized Lactic Acid Bacteria and their Selenium Bioaccummulation Capacity

Selenized lactic acid bacteria (LAB) represent potentially safe and effective sources of selenium (Se), essential for human health, as lactic acid fermentation improves Se bioavailability and reduces its toxicity. LAB are generally recognized as safe (GRAS) and widely used in fermented dairy products. To facilitate selenized LAB implementation as a functional food, we developed and characterized new Se-enriched strains based on the food industry commercial strains Streptococcus thermophilus CCDM 144 and Enterococcus faecium CCDM 922A as representatives of two LAB genera. We evaluated Se bioaccumulation capacity, Se biotransformation and growth ability in the presence of different sodium selenite concentrations (0–50 mg/L), and antioxidant properties (2, 2-diphenyl-1-picrylhydrazyl (DPPH) method) and cell surface hydrophobicity between Se-enriched and parental strains in vitro. Sodium selenite addition did not negatively influence growth of either strain; thus, 50 mg/L was chosen as the optimal concentration based on strain accumulation capacity. Selenization improved the antioxidant properties of both strains and significantly increased their cell surface hydrophobicity (p < 0.05). To our knowledge, this represents the first report of Se-enriched strain hydrophobicity as well as the first on Se speciation in families Enterococcaceae and Streptococcaceae. Moreover, both tested strains demonstrated good potential for Se-enrichment, providing a foundation for further in vitro and in vivo studies to confirm the suitability of these Se-enriched strains for industrial applications.
Reproduction of I‐type cosmic spherules and characterization in an Fe‐Ni‐O system

The chemical composition and texture of cosmic spherules are influenced by atmospheric conditions and the characteristics of their parent interplanetary particles. The objective of this study was to reproduce I‐type cosmic spherules, which consist mainly of Fe oxide and Fe‐Ni metal, and compare their textural characteristics with those of natural I‐type cosmic spherules. Thus, a series of rapid heating and quenching experiments were performed on free falling iron meteorite powders obtained from Canyon Diablo, in the United States. The experiments were conducted using a high‐temperature furnace with controlled gas flow rates at oxygen fugacities of FMQ + 2.4, FMQ, and FMQ − 2.5 log unit. The resulting Fe‐Ni metal and oxide phases showed the nonequilibrium state of the melted spherules formed during quenching. Two types of magnetite crystals in different orientations were found in iron oxide. As temperatures decreased, the molten metal was oxidized to form immiscible molten iron oxide that then covered the former. As the oxide melt increased at the expense of metal, magnetite began to crystallize from the iron oxide melt, as the liquidus phase, either on the surface or within the melt phase. The characteristics of the run products obtained under different oxygen fugacities were similar to those of natural I‐type cosmic spherules, which have textures and compositions that may contain information regarding the oxygen content of the upper atmosphere. Our study suggests that CO2‐bearing molecules in the atmosphere could form iron oxide with a texture similar to natural I‐type cosmic spherules. During this process, rapid crystallization of magnetite plays an important role in texture formation in disequilibrium states.
Effects of Coronal Restorations and Root Canal Filling Quality on Periapical Status in a Turkish Population

Amac: Bu calismanin amaci koronal restorasyon ve kok kanal dolgu kalitesinin periapikal saglik uzerindeki etkilerini degerlendirmektir. Materyal-Metot: Toplam 901 hastaya ait 1709 endodontik tedavi gormus dis degerlendirildi. Dijital panoramik radyograflar iki bagimsiz arastirmaci tarafindan incelendi. Degerlendirilen disler koronal restorasyonlarinin ve kok kanal dolgularinin kalitelerine gore siniflandirildi. Disler ayrica periapikal duruma gore saglikli veya hastalikli olarak ayrica degerlendirildi. Elde edilen sonuclar ki-kare ve Fisher’s exact testi kullanilarak analiz edildi. Bulgular: Toplamda 750 (%43,9) dis saglikli, 959 (%56,1) dis hastalikli olarak PAI skorla-masina gore siniflandirildi. Yeterli koronal restorasyon ve yeterli kok kanal dolgusuna sahip disler en yuksek basari oranini gosterdi. Yeterli kok kanal dolgusu ve yetersiz koronal restora-syona sahip disler, yetersiz kok kanal dolgusu ve yeterli koronal restorasyona sahip dislerden istatistiksel olarak anlamli derecede daha yuksek basari oranina sahipti (p<0,001). Yetersiz koronal restorasyon ve yetersiz kok kanal dolgusuna sahip disler en dusuk basari orani gosterdi. En sik tedavi edilen disler sirasiyla maksiller premolar, mandibular molarve maksiller molar dislerdi. Sonuc: Calismanin sonuclarira gore koronal restorasyonun kalitesi endodontik tedavinin basari uzerinde etkili bir faktor olsa da, kok kanal dolgusunun kalitesi periapikal saglik uzerindeki en etkili faktordur.
Chloroplast genome of tropical and sub-tropical fruit tree Clausena lansium (Rutaceae)

Abstract The Clausena lansium, originally native to the southern part of China and has a long history of cultivation, is a tree member of the family Rutaceae. Chloroplast genome sequences play a significant role in the development of molecular markers in plant phylogenetic and population genetic studies. In this study, we report the complete chloroplast genome sequence of C. lansium for the first time (accession number of MH047377). The chloroplast genome is 159,284 bp long and includes 113 genes. It’s LSC, SSC, and IR regions are 88,634, 18,896, and 25,877 bp long, respectively. Phylogenetic tree analysis exhibited that C. lansium was clustered with other Rutaceae species with high bootstrap values.
Navigating the territories of transition: An exploration of the experiences of transnational social workers in Aotearoa New Zealand

This qualitative study conducted three focus groups with transnational social workers (TSWs) in three cities of Aotearoa New Zealand. The aim of the study was to examine the transitional experience of TSWs, particularly in relation to any strategies and mechanisms existing in the host country to facilitate their personal and professional transition. A significant finding is that a coherent profession-wide programme for facilitating the transition is absent as the existing practices are mostly within the employer–employee relationships. Transitional experiences of TSWs are explained using the metaphor of ‘territory’ and some strategies for effective transition are suggested.
An experimental test of temperature‐dependent selection on mitochondrial haplotypes in Callosobruchus maculatus seed beetles

Abstract Mitochondrial DNA (mtDNA) consists of few but vital maternally inherited genes that interact closely with nuclear genes to produce cellular energy. How important mtDNA polymorphism is for adaptation is still unclear. The assumption in population genetic studies is often that segregating mtDNA variation is selectively neutral. This contrasts with empirical observations of mtDNA haplotypes affecting fitness‐related traits and thermal sensitivity, and latitudinal clines in mtDNA haplotype frequencies. Here, we experimentally test whether ambient temperature affects selection on mtDNA variation, and whether such thermal effects are influenced by intergenomic epistasis due to interactions between mitochondrial and nuclear genes, using replicated experimental evolution in Callosobruchus maculatus seed beetle populations seeded with a mixture of different mtDNA haplotypes. We also test for sex‐specific consequences of mtDNA evolution on reproductive success, given that mtDNA mutations can have sexually antagonistic fitness effects. Our results demonstrate natural selection on mtDNA haplotypes, with some support for thermal environment influencing mtDNA evolution through mitonuclear epistasis. The changes in male and female reproductive fitness were both aligned with changes in mtDNA haplotype frequencies, suggesting that natural selection on mtDNA is sexually concordant in stressful thermal environments. We discuss the implications of our findings for the evolution of mtDNA.
Analysis of Photosynthetic Systems and Their Applications with Mathematical and Computational Models

In biological and life science applications, photosynthesis is an important process that involves the absorption and transformation of sunlight into chemical energy. During the photosynthesis process, the light photons are captured by the green chlorophyll pigments in their photosynthetic antennae and further funneled to the reaction center. One of the most important light harvesting complexes that are highly important in the study of photosynthesis is the membrane-attached Fenna–Matthews–Olson (FMO) complex found in the green sulfur bacteria. In this review, we discuss the mathematical formulations and computational modeling of some of the light harvesting complexes including FMO. The most recent research developments in the photosynthetic light harvesting complexes are thoroughly discussed. The theoretical background related to the spectral density, quantum coherence and density functional theory has been elaborated. Furthermore, details about the transfer and excitation of energy in different sites of the FMO complex along with other vital photosynthetic light harvesting complexes have also been provided. Finally, we conclude this review by providing the current and potential applications in environmental science, energy, health and medicine, where such mathematical and computational studies of the photosynthesis and the light harvesting complexes can be readily integrated.
An evaluation of methods for distinguishing between juvenile and adult mountain hares Lepus timidus

Different age determination methods were compared to find a practical method for distinguishing between young and adult mountain hares Lepus timidus. The age of the hares was determined using: 1) the ossification stage of the radius and ulna, and 2) the dry weight of the eye lens. The ossification stage of the bones was examined with the unaided eye and palpation, and by using radiography. The proportion of young was higher when the bones were examined using radiography rather than the unaided eye, except in early autumn when the two methods led to the same results. Age determination based on bone examination using the unaided eye gave more reliable results than age determination based on radiography; this became evident when the results were compared with the reproductive status of females or with the dry weight of the eye lens. Using an eye lens weight of 0.25 g as a discriminating value between young and adult hares, gave an age determination similar to that derived from bone examinations using the unaided eye in 90% of the cases. Age determination based on examination of the radius and ulna using the unaided eye and palpation, together with the eye lens weight thus forms a reliable and practical method for distinguishing between young and adult mountain hares, and radiography is only necessary when examining live animals.
Elevation as a selective force on mitochondrial respiratory chain complexes of the Phrynocephalus lizards in the Tibetan plateau

Abstract Animals living in extremely high elevations have to adapt to low temperatures and low oxygen availability (hypoxia), but the underlying genetic mechanisms associated with these adaptations are still unclear. The mitochondrial respiratory chain can provide >95% of the ATP in animal cells, and its efficiency is influenced by temperature and oxygen availability. Therefore, the respiratory chain complexes (RCCs) could be important molecular targets for positive selection associated with respiratory adaptation in high-altitude environments. Here, we investigated positive selection in 5 RCCs and their assembly factors by analyzing sequences of 106 genes obtained through RNA-seq of all 15 Chinese Phrynocephalus lizard species, which are distributed from lowlands to the Tibetan plateau (average elevation >4,500 m). Our results indicate that evidence of positive selection on RCC genes is not significantly different from assembly factors, and we found no difference in selective pressures among the 5 complexes. We specifically looked for positive selection in lineages where changes in habitat elevation happened. The group of lineages evolving from low to high altitude show stronger signals of positive selection than lineages evolving from high to low elevations. Lineages evolving from low to high elevation also have more shared codons under positive selection, though the changes are not equivalent at the amino acid level. This study advances our understanding of the genetic basis of animal respiratory metabolism evolution in extreme high environments and provides candidate genes for further confirmation with functional analyses.
Rescue of a developmental arrest caused by a C. elegans heat-shock transcription-factor mutation by loss of ribosomal S6-kinase activity

The widely conserved heat-shock response, regulated by heat shock transcription factors, is not only essential for cellular stress resistance and adult longevity, but also for proper development. However, the genetic mechanisms by which heat-shock transcription factors regulate development are not well understood. In C. elegans, we conducted an unbiased genetic screen to identify mutations that could ameliorate the developmental arrest phenotype of a heat-shock factor mutant. Here we show that loss of the conserved translational activator rsks-1/S6-Kinase, a downstream effector of TOR kinase, can rescue the developmental-arrest phenotype of hsf-1 partial loss-of-function mutants. Unexpectedly, we show that the rescue is not likely caused by reduced translation, nor to activation of any of a variety of stress-protective genes and pathways. Our findings identify an as-yet unexplained regulatory relationship between the heat-shock transcription factor and the TOR pathway during C. elegans’ development.
OPINIONS OF TEACHER CANDIDATES ON DISTANCE EDUCATION IMPLEMENTED DURING THE COVID-19 PANDEMIC PERIOD

The learning environment, learning process and the opinions and suggestions for the problems concerning the process of students participating in distance education is thought to contribute to better planning and conducting distance education lessons. With this respect, the purpose of this study is to detect the reflections of the COVID-19 pandemic period on undergraduate education through opinions of teacher candidates. The qualitative internet research, which is one of the qualitative research models, was preferred for the study. The participant group was identified through the maximum sampling method. The participant group consisted of 27 teacher candidates studying in year 3. and year 4. The semi-structured interview form developed by the instructors was used as the data collection instrument. Content analysis was conducted through the Nvivo 11 software when analyzing the data. Positive-negative opinions of teacher candidates concerning distance education and the announcements made throughout the distance education process were collected for the study. In addition, the negative outcomes it caused on the participants, its reflections on the educational process, opinions-suggestions concerning assessment and evaluation and solution advices for the process were also identified. Article visualizations:
Anatomy, relationships and palaeobiogeographic implications of the first Neogene holomorphic stingray (Myliobatiformes: Dasyatidae) from the early Miocene of Sulawesi, Indonesia, SE Asia

The early Miocene stingray † Trygon vorstmani represented by a single specimen collected from the fish-bearing limestones of the Tonasa Formation of SW Sulawesi, Indonesia, is redescribed here in detail. This taxon exhibits a unique combination of features that clearly support the presence of a new genus, † Protohimantura gen. nov. and its assignment to the whiptail stingrays (Dasyatidae) of the subfamily Urogymninae. The morphological and phylogenetic affinities of † Protohimantura gen. nov. with the living whiprays suggest a close association of this taxon with tropical shallow-water habitats hypothesized for the SW Sulawesi palaeoenvironment during early Miocene. Moreover, this occurrence, which also represents the first holomorphic stingray specimen from the Neogene, provides new insights into the role of the Indo-Australian Archipelago for the evolutionary history of fishes associated with reefs in the context of the shift of the marine biodiversity hotspot across the globe during the last 50 million years.
Harmonic current suppression method with adaptive filter for permanent magnet synchronous motor

ABSTRACT Due to the distortion of air gap magnetic field and the inherent non-linear characteristics of the inverter, the stator current of permanent magnet synchronous motor (PMSM) contains a large number of high order harmonic components, which distorts the current waveform and generates torque ripple, limiting the application of the PMSM in high speed and precision situations. To solve this problem, a harmonic current suppression method is proposed based on synchronous rotating coordinate transformation theory and adaptive filtering algorithm. The PMSM harmonic mathematical model is established and the coordinate transformation method is used to extract the 5th and 7th harmonic currents. On the basis of the original double closed-loop control system, the harmonic current loop is added, and the harmonic components are suppressed by injecting harmonic voltages. In order to improve the filtering effect and reduce the harmonic content, an adaptive filter is designed to replace the conventional low pass filter in the process of harmonic current extraction. According to the results of coordinate transformation, the adaptive filter continuously adjusts the parameters online through the least mean square (LMS) algorithm to extract the harmonic current. The simulation and experimental results proved the correctness and effectiveness of the proposed method.
TQM factors and organisational results in the EFQM excellence model framework: an explanatory and predictive analysis

Within the framework of Total Quality Management (TQM) and the EFQM Excellence Model (EEM), the main objective of this paper is to develop a causal-predictive analysis of the relationships between soft and strategic-hard EFQM factors and the organisational results (customers, people, society and key results). ,From a causal-predictive perspective, four EEM models, designed for each organisational result, are compared applying partial least squares structural equation modelling (PLS-SEM) and using a sample with 225 Spanish organisations. ,The results confirm that soft and strategic-hard EFQM factors constitute a socio-technical system in which there are multiple direct and indirect relationships, between these factors and the results. Finally, the predictive nature of the proposed models is confirmed, highlighting the predictive performance of the people results model. ,The results can lead to an improvement in organisational performance, as the developed models enable managers to anticipate the effects of their management decisions on those results concerning customers, people, society and key business results. ,First, a novel way of grouping TQM enabler factors has been proposed within the EEM framework. Second, four research models have been generated, which allow carrying out an in-depth study of the direct and indirect relationships, between soft and strategic-hard EFQM factors and result variables. Finally, this contribution has applied the most updated techniques in order to assess the prediction performance of the four research models posited.