Miracle-dz/UniFAR-FTUs huggingface dataset:
TardisDB: Extending SQL to Support Versioning

Online encyclopaedias such as Wikipedia implement their own version control above database systems to manage multiple revisions of the same page. In contrast to temporal databases that restrict each tuple's validity to a time range, a version affects multiple tuples. To overcome the need for a separate version layer, we have created TardisDB, the first database system with incorporated data versioning across multiple relations. This paper presents the interface for TardisDB with an extended SQL to manage and query data from different branches. We first give an overview of TardisDB's architecture that includes an extended table scan operator: a branch bitmap indicates a tuple's affiliation to a branch and a chain of tuples tracks the different versions. This is the first database system that combines chains for multiversion concurrency control with a bitmap for each branch to enable versioning. Afterwards, we describe our proposed SQL extension to create, query and modify tables across different, named branches. In our demonstration setup, we allow users to interactively create and edit branches and display the lineage of each branch.
TOWARDS ACTIVATION OF THE EMPATHIC RESOURCES DURING TERMINAL CARE – AN ART AND/OR A NECESSITY?

A brief historical-analytical review of the origin, essence, and development of empathy has been made. The theoretical measurements in the study of the empathic ability are subject to special attention. On the basis of topical definitions of the concept, the application of the approach in different spheres of life, and more specifically in medical practice, has been discussed. The types of communicative behavior in primary medical practice have been differentiated. A theoretical, applied method of communication intervention within the framework of operationalization and scaling of the empathic interaction is proposed. On the basis of the assumption of a genetically determined property of co-experience, the preconditions for the establishment of optimal interpersonal context upon exchange of information between the physician and the patient and making medical decisions have been outlined. Led by the so systematized and analyzed models and considering the specification of the transformed and activated empathic resources in cases of terminal conditions, an attempt has been made for the presentation of an extensive type of empathic interaction, applied in palliative medicine. The outlining of key messages in cases of terminal conditions in the specified model is complex and at the same time an open, dynamic process, requiring adaptation and enrichment with parameters of religious, ethnical and social nature, and other factors of psychological, spiritual and bio-ethical type in the complex interactive space of palliative medicine.
Study of Person Re-Identification using Adaptive Spatial Temporal Attention Aware Learning with Gaussian Filter

-Individual re-ID is a difficult assignment mostly because of variables, for example, foundation mess, posture, brightening and camera perspective varieties. These components obstruct the way toward extricating hearty and discriminative portrayals, consequently keeping various personalities from being effectively recognized. To improve the portrayal learning, generally neighborhood highlights from human body parts are separated. Be that as it may, the normal practice for such a procedure has been founded on bouncing box part identification. Right now, propose to embrace Adaptive Spatial-Temporal Attention - Aware Learning and Gaussian Filter which, because of its pixel-level exactness and capacity of demonstrating subjective shapes, is normally a superior other option. Our proposed (ASTAL-GF) incorporates learning face to face re-distinguishing proof and impressively outflanks its counter pattern, however accomplishes cutting edge execution. Our proposed techniques improve best in class individual re-recognizable proof on exactness of worldwide and nearby highlights according to combination rate is improve by 1.02%, thus acknowledgment rate may improve. The exactness of nearby and worldwide implanting size is increment by 0.736% and 1.14% separately. The precision relying upon the edges for neighborhood separation and worldwide separation is increment by 0.735% and 1% individually. The exhibition of re-recognizable proof procedure is improved by 2.73%.
Methodologies for Processing Fixed Bed Combustor Data

ABSTRACT Experiments are conducted on a laboratory-scale fixed bed combustor. This article discusses some of the data analysis methodologies that define the onset of steady state conditions, which are widely reported in the literature but poorly defined. The effects of using different methods to determine the onset of the steady state performance, and to correct thermocouple data so as to account for radiative effects, are also presented. Results show that using a combination of CO and NO emissions with free-board temperatures (at multiple axial positions) is more effective than other emissions, using temperatures (only) or the fuel burning rate (kg m–2 s–1). An important indicator is to analyze the percentile deviation of temperatures and emissions, compared to only using the time evolution of these variables. To characterize the significance of correcting thermocouple data for radiative (wall) losses, two numerical models (aspirated and bare bead) were compared. Radiative effects on thermocouples were found to be most prominent nearer to the downstream secondary air inlet due to the cooler wall temperature. Due to the likely radiative effects from freeboard deflectors, the sensitivity of these outcomes to the presence of downstream deflectors is also presented.
Effect of substituting barley with sorghum on starch digestion, rumen microbial yield and growth in Iranian Baluchi lambs fed high concentrate diets

This study investigated the effects of substituting barley (B) with sorghum (S) on site and extent of in vivo disappearance of dry matter (DM), starch and nitrogen in the gastrointestinal tract (GIT), microbial protein synthesis and growth in finishing lambs. 18 male Iranian Baluchi lambs were randomly allocated to three dietary treatments in a complete randomized design (CRD). Dietary grain treatments were: barley (B) as control, barley: sorghum (BS) (in equal amount) and sorghum (S). At the end of the feeding trial, the lambs were euthanized and digesta contents in the different sections of the GIT were collected to determine DM, starch and nitrogen disappearance. Starch intake of lambs on barley (B) diet was lower than those fed S and BS but lambs on B diet had higher (P<0.05) ruminal DM content and starch disappearance resulting in lower (P<0.05) ruminal pH than those fed diets containing sorghum. Although lambs on B diet had higher (P<0.05) volatile fatty acids (VFA) concentration in the rumen, highest ruminal microbial protein synthesis was recorded in lambs fed BS diet, presumably due to the more synchronized release of energy and nitrogen together with the higher rumen pH appropriate for microbial growth. Although a higher (P<0.05) outflow rate (g/d) of starch into the small intestine was observed for high sorghum (S) diet than the BS and control (B) diets, lambs on S diet had the lowest microbial-N flow to small intestine, resulting in the lowest N and starch digestibility in the small intestine and total track. There was a clear positive relationship between microbial N (MN) synthesis and starch disappearance in the small intestine, with BS lambs producing the highest and S lambs lowest MN yield (32.2 and 24.1 g/d, respectively) and corresponding starch disappearance was 0.87 and 0.58, respectively. The majority of the post-ruminal nutrients (DM, N and starch) were hydrolyzed in the distal-duodenum and anterior segments of jejunum. It can be concluded that substitution of barley with 0.50 sorghum increased outflow of starch from the rumen, enhanced starch digestibility and absorption in the small intestine and resulted in higher growth rate as evident by the higher average daily gain (ADG) and more efficient feed conversion ratio (FCR) recorded for lambs on the BS diet.
Changes In Youth Executive Function During Trauma-Focused Cognitive Behavioral Therapy: Associations with PTSD Symptom Severity

CHANGES IN YOUTH EXECUTIVE FUNCTION DURING TRAUMA-FOCUSED COGNITIVE BEHAVIORAL THERAPY: ASSOCIATIONS WITH PTSD SYMPTOM SEVERITY Amy Hyoeun Lee Youth with maltreatment and/or interpersonal trauma histories often demonstrate significant executive function difficulties, which may negatively affect self-regulation and represent a transdiagnostic risk factor for trauma-related psychopathology and impaired functioning across domains. Trauma-Focused Cognitive Behavioral Therapy (TF-CBT) is an evidence-based treatment for posttraumatic stress disorder (PTSD) symptoms and other mental health sequelae among maltreated youth; however, the potential impact of impact of TF-CBT on youth executive function difficulties has not been examined despite emerging evidence that executive function may be related to PTSD symptom severity among trauma-exposed youth. The current study sought to evaluate caregiver-reported executive function as a treatment outcome of TF-CBT among youth with interpersonal trauma histories and examine the associations between executive function and PTSD symptom trajectories. Univariate latent growth models, allowing for interindividual heterogeneity in intercepts and slopes, were used to estimate linear trajectories of caregiver-reported executive function difficulties among youth ages 6 to 17 (N = 278). Results demonstrated reductions in global and specific executive function difficulties during treatment for both children and adolescents. Bivariate latent growth models, estimated separately for children and adolescents, were used to examine the associations between executive function and PTSD change. Among children ages 6 to 11, higher initial levels of PTSD symptoms were associated with higher initial levels of difficulties in Attentional Control, r = . 36, SD = . 15, 95% CI [. 06, . 65] and Behavioral Control, r = . 35, SD = . 17, 95% CI [-. 87, . 81]. Among adolescents ages 12 to 17, rates of decrease in overall executive function difficulties were positively associated with rates of PTSD symptom reduction, r = . 59, SD = . 21, 95% CI [. 11, . 90]. Findings highlight caregiver-observed improvements in youth executive function concerns during TF-CBT and suggest that rates of reduction in executive function difficulties and PTSD symptoms are interrelated among adolescents.
Solvent cleaning and wettability of technical steel and titanium surfaces

The ability of the cleaning agents such as cyclohexane, acetone, isopropanol and hydrogen peroxide to remove oil from technical steel and titanium samples was studied in systematic experiments. The composition of the organic residues and the layer thickness on the differently cleaned surfaces were determined via X-ray photoelectron spectroscopy analysis, and the corresponding water contact angles were measured. The ability of the cleaning agents to remove oil was found to increase in the following order: acetone, isopropanol, cyclohexane and hydrogen peroxide. The relationship between the chemical composition of the residues and the observed contact angles is investigated, and a quantitative correlation is developed.
Paired T-Test for Superiority by a Margin

Introduction This procedure provides reports for making inference about the superiority of a treatment over a control by a given margin from paired data. The question of interest is whether the mean of treatments minus controls is larger than some superiority margin. Another way of saying this is that the treatment is better than the control by some value called the margin. Two different test statistics may be used: the parametric Paired T-Test and the nonparametric Wilcoxon SignedRank Test.
Analysis of the 60/60 Sign and Other Right Ventricular Parameters by 2D Transthoracic Echocardiography as Adjuncts to Diagnosis of Acute Pulmonary Embolism

Introduction The 60/60 sign in 2D transthoracic echocardiography (TTE) - a combination of pulmonary acceleration time (PAT) less than 60 milliseconds and tricuspid regurgitation (TR) jet gradient of less than 60 mmHg - has been found to be specific for the diagnosis of pulmonary embolism (PE). Materials and methods An observational prospective analysis was carried out on cases of suspected PE presenting to the emergency room (ER). TTE was performed on all cases with suspected PE prior to computed tomography pulmonary angiography (CTPA). Emphasis was placed on measurement of PAT and early systolic notching (ESN) on the pulsed wave (PW) Doppler of the pulmonary valve, TR jet gradient, right ventricle systolic excursion velocity (RV S’) by tissue doppler imaging (TDI), tricuspid annular plane systolic excursion (TAPSE), and right ventricle to left ventricle end-diastolic dimension ratio (RV:LV EDD) in modified parasternal short-axis view. These signs were taken as screening tests and compared to CTPA as the standard test. Patients were followed up until hospital discharge or death. Observations Fifty-six cases of suspected PE were enrolled for the study. Of these, 24 cases of PE were confirmed by CTPA. Out of 24 cases of PE, 15 were high-risk PE, six were intermediate high-risk PE, and three were intermediate low-risk PE. The mean age was 53.07±9.79 years with a male-to-female ratio of 1.95:1. The 60/60 sign was present in 70.83% of cases of PE. RV:LV EDD in a modified short-axis view of more than 0.9 was present in 91.67% of cases of PE, and ESN on the PW Doppler of the pulmonary valve was present in 75% of cases of PE. The 60/60 sign, RV:LV EDD ratio more than 0.9, and ESN showed sensitivities of 70.83%, 91.67%, 75%, and specificities of 93.75%, 75%, and 100%, respectively for PE. For prediction of mortality, presence of the 60/60 sign (Odds Ratio=8.13, p-value=0.034) and ESN (Odds Ratio=17.50, p-value=0.02) were statistically significant. Conclusions 60/60 sign and ESN are specific for the diagnosis of PE but have poor sensitivity.
Dermatopontin as a potential pathogenic factor in endometrial cancer

The present study aimed to determine the differential expression profiles of proteins in endometrial carcinoma and to screen the proteins associated with the occurrence and development of endometrial cancer (EC). In total, 15 samples of human EC and paracancerous tissues were selected for proteomic analysis using a label-free quantification method based on liquid chromatography-tandem mass spectrometry. The differential proteins were analysed using bioinformatics and verified using reverse transcription-quantitative PCR (RT-qPCR) and western blotting. Finally, the expression of differential proteins in 75 endometrial carcinoma samples and 30 normal endometrial tissue samples were detected using immunohistochemical staining, and the associations between differential protein expression and clinicopathological features were analysed. In total, 579 up-regulated proteins and 346 down-regulated proteins were identified between the two groups and seven proteins with the most significant differences were selected; these proteins included interferon-induced protein with tetratricopeptide repeats 3, poly(ADP-ribose) polymerase family member 9, solute carrier family 34 member 2, cytochrome b5 reductase 1, protein tyrosine phosphatase non-receptor type 1, dermatopontin (DPT) and secretory leukocyte peptidase inhibitor. RT-qPCR and western blotting showed that DPT expression was down-regulated (P<0.001), which was consistent with the mass spectrometry results. The immunohistochemical staining results showed that the positive expression of DPT in EC and normal endometrial tissues was statistically significant (P<0.001). The positive expression of DPT was significantly decreased in poorly differentiated, late stage, lymph node metastasis and myometrial invasion depth ≥1/2 samples (P<0.05). DPT expression was significantly lower in EC, which might play role in the pathogenesis of EC.
DigiKnowIt News: Educating youth about pediatric clinical trials using an interactive, multimedia educational website

Pediatric clinical trials allow for the testing of appropriate and effective treatments for children. However, some challenges exist with recruitment. This study examined the effectiveness of DigiKnowIt News, an interactive, multimedia website (which includes activities, videos, and comic books) designed to educate children about clinical trials. A randomized controlled trial was conducted in 2018 with 91 participants (M age = 10.92 years; SD = 2.06). Participants were randomly assigned to intervention or wait-list control groups and completed questionnaires at pretest and posttest (1 week later) about their knowledge, attitudes, beliefs about clinical trials, and self-efficacy for participating in clinical trials. Participants in the intervention group received access to DigiKnowIt News between pretest and posttest and completed a satisfaction questionnaire at posttest. At the end of the study, participants in the wait-list control group were offered the option to use the website and complete a satisfaction questionnaire. At posttest, participants in the intervention group, compared to participants in the wait-list control group, had more knowledge about clinical trials and more reported confidence for participating in clinical trials. Participants reported high levels of satisfaction with DigiKnowIt News. The findings suggest that an educational website can improve factors related to increasing rates of participation in clinical trials.
A single stiffened nucleus alters cell dynamics and coherence in a monolayer

Force transmission throughout a monolayer is the result of complex interactions between cells. Monolayer adaptation to force imbalances such as singular stiffened cells provides insight into the initiation of disease and fibrosis. Here, NRK‐52E cells transfected with ∆50LA, which significantly stiffens the nucleus. These stiffened cells were sparsely placed in a monolayer of normal NRK‐52E cells. Through morphometric analysis and temporal tracking, the impact of the singular stiffened cells shows a pivotal role in mechanoresponse of the monolayer. A method for a detailed analysis of the spatial aspect and temporal progression of the nuclear boundary was developed and used to achieve a full description of the phenotype and dynamics of the monolayers under study. Our findings reveal that cells are highly sensitive to the presence of mechanically impaired neighbors, leading to generalized loss of coordination in collective cell migration, but without seemingly affecting the potential for nuclear lamina fluctuations of neighboring cells. Reduced translocation in neighboring cells appears to be compensated by an increase in nuclear rotation and dynamic variation of shape, suggesting a “frustration” of cells and maintenance of motor activity. Interestingly, some characteristics of the behavior of these cells appear to be dependent on the distance to a ∆50LA cell, pointing to compensatory behavior in response to force transmission imbalances in a monolayer. These insights may suggest the long‐range impacts of single cell defects related to tissue dysfunction.
Added Value of Quantitative Apparent Diffusion Coefficient Values for Neuroprognostication After Cardiac Arrest

Objective To test the prognostic value of brain MRI in addition to clinical and electrophysiologic variables in patients post–cardiac arrest (CA), we explored data from the randomized Neuroprotect Post-CA trial (NCT02541591). Methods In this trial, brain MRIs were prospectively obtained. We calculated receiver operating characteristic (ROC) curves for the average apparent diffusion coefficient (ADC) value and percentage of brain voxels with an ADC value <650 × 10−6 mm2/s and <450 × 10−6 mm2/s. We constructed multivariable logistic regression models with clinical characteristics, EEG, somatosensory evoked potentials (SSEP), and ADC value as independent variables to predict good neurologic recovery. Results In 79/102 patients, MRI data were available and in 58/79 patients all other data were available. At 180 days post-CA, 25/58 (43%) patients had good neurologic recovery. In univariable analysis of all tested MRI measures, average ADC value in the postcentral cortex had the highest accuracy to predict good neurologic recovery, with an area under the ROC curve (AUC) of 0.78. In the most optimal multivariable model, which also included corneal reflexes and EEG, this measure remained an independent predictor of good neurologic recovery (AUC 0.96, false-positive 27%). This model provided a more accurate prediction compared to the most optimal combination of EEG, corneal reflexes, and SSEP (p = 0.03). Conclusions Adding information on brain MRI in a multivariable model may improve the prediction of good neurologic recovery in patients post-CA. Classification of Evidence This study provides Class III evidence that MRI ADC features predict neurologic recovery in patients post-CA.
Reinduction chemotherapy regimen involved decitabine and cladribine improves the prognosis of patients with relapsed or refractory acute myeloid leukemia: A preliminary study

Relapsed/refractory acute myeloid leukemia (R/R‐AML) is characterized by a high incidence, short survival and poor prognosis. Presently, no unified effective reinduction chemotherapy regimen has been developed. Therefore, the use of reinduction chemotherapy regimens before allogeneic hematopoietic stem cell transplantation (allo‐HSCT) is controversial. Our study aims to analyze the prognostic factors of R/R‐AML and to evaluate the efficacy of the regimen involved decitabine, cladribine, idarubicin or homoharringtonine, and cytarabine (DCIA/DCHA). Clinical and survival data of 112 R/R‐AML patients were obtained. Among the 102 R/R‐AML patients that were treated with conventional regimens, we found that poor prognosis was related to a greater proportion of bone marrow blasts (>70%) and not achieving complete remission (non‐CR) after the first reinduction chemotherapy. Hematopoietic stem cell transplantation (of which 89.47% was allo‐HSCT) following CR after the first reinduction chemotherapy often improves the prognosis. Of the 10 R/R‐AML patients that were treated with the DCIA/DCHA regimen, nine patients achieved CR or complete response with incomplete hematopoietic recovery (CRi) after one course of chemotherapy. The median overall survival of the 10 patients was 10.14 (1.23‐29.13) months. In conclusion, non‐CR was associated with poor prognosis in R/R‐AML. Therefore, intensive reinduction chemotherapy should be selected to achieve CR. This creates conditions for allo‐HSCT and improves prognosis of R/R‐AML patients. The DCIA/DCHA regimen showed good efficacy and tolerable adverse reactions in R/R‐AML treatment. This combination may be used as a bridging regimen for allo‐HSCT in R/R‐AML.