Miracle-dz/UniFAR-FTUs huggingface dataset:
Nonlinear Dynamic Analysis of Three-Dimensional Elasto-Plastic Solids by the Meshless Local Petrov-Galerkin (MLPG) Method

The meshless local Petrov-Galerkin approach is proposed for the nonlinear dynamic analysis of three-dimensional (3D) elasto-plastic problems. Galerkin weak-form formulation is applied to derive the discrete governing equations. A weak formulation for the set of governing equations is transformed into local integral equations on local sub-domains by using a unit test function and local weakform formulation in three dimensional continua for the general dynamic problems is derived. Three dimensional Moving Least-Square (MLS) approximation is considered as shape function to approximate the field variable of scattered nodes in the problem domain. Normality hypothesis of plasticity is adopted to define the stress-strain relation in elasto-plastic analysis and the unknown plastic multiplier is obtained by the consistency condition. Von Mises yield criterion in three dimensional space is used as a yield function to determine whether the material has yielded. The Newmark time integration method in an incremental form is used to solve the final system of nonlinear second order Ordinary Differential Equations (ODEs). Several numerical examples are given to demonstrate the accuracy and effectiveness of the present numerical approach.
Blinding efficacy,

Mouth rinsing with a sweet solution increases energy expenditure and decreases appetite during 60 minutes of self-regulated walking exercise. Abstract Carbohydrate mouth rinsing can improve endurance exercise performance and is most 21 ergogenic when exercise is completed in the fasted state. This strategy may also be beneficial 22 to increase exercise capacity and the energy deficit achieved during moderate intensity exercise 23 relevant to weight control when performed after an overnight fast. Eighteen healthy men 24 (mean(SD); age 23(4)years, body mass index 23.1(2.4)kg.m -2 ) completed a familiarisation trial 25 and three experimental trials. After an overnight fast, participants performed 60-minutes of 26 treadmill walking at a speed that equated to a rating of perceived exertion of 13 (“fairly hard”). 27 Participants manually adjusted the treadmill speed to maintain this exertion. Mouth rinses for 28 the experimental trials contained either a 6.4% maltodextrin solution with sweetener (CHO), a 29 taste-matched placebo (PLA) or water (WAT). Appetite ratings were collected using visual 30 analogue scales and exercise energy expenditure and substrate oxidation were calculated from 31 online gas analysis. Increased walking distance during CHO and PLA induced greater energy 32 expenditure compared with WAT (mean difference (90% CI); 79(60)kJ; P=0.035; d =0.24 and 33 90(63)kJ; P=0.024; d =0.27, respectively). Appetite area under the curve was lower in CHO and 34 PLA than WAT (8(6)mm; P=0.042; d =0.43 and 6(8)mm; P=0.201; d =0.32, respectively). 35 Carbohydrate oxidation was higher in CHO than PLA and WAT (7.3(6.7)g; P=0.078; d =0.47 36 and 10.1(6.5)g; P=0.015; d =0.81, respectively). This study provides novel evidence that mouth 37 rinsing with a sweetened solution may promote a greater energy deficit during moderate 38 exertion walking exercise by increasing energy expenditure and decreasing appetite. A placebo 39 effect may have contributed to these benefits.
The Examination of Intra-group Agreement of Q-Sort

ABSTRACT A technique for assessing the agreement between the Q-sorts of two or more groups of subjects is presented which relies on the relationship between the Kendall coefficient of concordance (W) and the Spearman rank order correlation (rho). The proposed statistical treatment of Q-sort data involves the use of a number of intercorrelations rather than a direct computation of W. This method provides insight into the level and nature of the intra-group agreement and permits the use of certain readily available computer programs. (Author/NV)
University of Birmingham Behavioral profiles.

• Users may freely distribute the URL that is used to identify this publication. • Users may download and/or print one copy of the publication from the University of Birmingham research portal for the purpose of private study or non-commercial research. • User may use extracts from the document in line with the concept of ‘fair dealing’ under the Copyright, Designs and Patents Act 1988 (? ) • Users may not further distribute the material nor use it for the purposes of commercial gain.
Modelling Motorcycle-Related Head Injury Trends for Thailand Following the 100% Motorcycle Helmet Use Campaign Using Log-linear Model

The aim of this paper is to examine trends of motorcycle related head injuries in HRH Princess Maha Chakri Sirindhorn Medical Center, Nakhon Nayok province, Thailand, following the 100% Motorcycle Helmet Use campaign by using log-linear models. Since the injuries count data is overdispersion, the Poisson log-linear model is not reasonable. Consequently, the negative binomial log-linear model accounted for overdispersion is used, and it fits the data very well. The fitted model indicated the increasing trend of head injuries after the 100% Motorcycle Helmet Use campaign was lunched over the years 2011-2016. It is increasing at the rate 1.13% per month. ______________________________
STREAMED SOUNDSCAPES CREATED TO HELP INFANTS SLEEP

This paper reports results of a survey that was conducted to assess the use and efficacy of soundscapes composed for an DAB+ radio station and on demand audio App ‘ABC-Kids listen’ provided by the Australian Broadcasting Corporation (ABC). The soundscapes were a series of previously composed pieces titled Sleep Through. 21 people who had listened to one or more of the compositions completed the survey as part of a qualitative study of how music can aid sleep. Results suggested very high overall efficacy, but also revealed applications to situations that did not involve aiding the parents and/or their infants to sleep. These included using Sleep Through for pleasure, and for breast feeding. Open-ended responses to the survey were organized into themes labelled: Relaxation (the most prevalent theme), Associations (often linked to the title and environments portrayed in the soundscape), Distraction (strongly related to Relaxation), and Auditory Masking. The theme labelled Habit (using Sleep Through to develop healthy sleeping habits) was also considered, but exhibited too great an overlap with other themes. The themes were strongly connected with those found in the literature investigating the use of music for sleep by adults, and also supported the approach of the composer. The study was conducted in collaboration with the composer, with his intentions and responses to the study forming an integral part of the research.
Four Separate Elements of Recombination by the Cumulative Activity Enhancement of Antibody Class-Switch

Class-switch recombination of Ab isotype is mediated by a recombinational DNA deletion event and must be robustly upregulated during Ag-driven differentiation of B cells. The enhancer region 3 9 of the C a gene is important for the upregulation of switch recombination. Using a transgene of the entire H chain C region locus, we demonstrate in this study that it is the four 3 9 enhancer elements themselves (a total of 4.7 kb) that are responsible for the upregulation rather than the 24 kb of DNA in between them. Neither allelic exclusion nor transgenic m expression is reduced by deletion of the four 3 9 enhancers. We also test deletions of two or three of the 3 9 enhancers and show that deletion of more 3 9 enhancers results in a progressive reduction in both switch recombination and germline transcription of all H chain genes. Nevertheless, we ﬁnd evidence for special roles for some 3 9 enhancers; different H chain genes are affected by different 3 9 enhancer deletions. Thus, we ﬁnd that the dramatic induction of class-switch recombination during Ag-driven differentiation is the result of an interaction among four separated regulatory elements. The Journal of Immunology , 2011, 187: 4733–4743. the of IgM to IgE, IgA, or IgG. a recombinational deletion event that begins in the intron between the V region-encoding exon and the m C exon upstream of the C ε , C a , or one of the four C g H chain genes (1, 2). in B upregulated Ag-driven B cell differentiation progeny B an isotype GACCA-TACCCTGCTATGAGTCC (23982–24003) and TGGTGCTCAGCACT- GAGTTCTG (complement of 25374–25395), which resulted in a 249-bp PCR fragment. Transgenic tested for the HS4 deletion using primers GAAACTCATATCAGCCTCTGCAC (27053–27075) and GTTT-CTGGGTGTCTCTGTGTCTGTTC (complement of 28869–28894), which re- sulted in a 709-bp PCR fragment. All with has been approved by the University of Michigan Committee on Care and Use of Animals, protocol 08147. followed by phosphorimager anal- ysis of polyacrylamide gels. CSR was also estimated by quantiﬁcation of the secreted Ig after culture of splenic B cells (from a single mouse or a pool of two mice) for 7 d with B cell activators and cytokines. Analysis of secreted transgenic IgG1 a employed ELISA with anti-IgG1 a –coating Abs and anti-IgG1–developing Abs. Analysis of secreted transgenic IgG2a employed anti-Flag–coating Abs and anti-IgG2a–developing Abs. Analy- sis of secreted transgenic IgA employed anti-IgA–coating Abs, an in-termediate AD8 mAb (to the transgenic idiotype), and an anti-rat IgG- developing Ab. All ELISA developing Abs were conjugated to alkaline phosphatase.
Daniel, Zoe and Swali, Angelina and Emes, Richard D. and Langley-Evans, Simon C. (2016) The effect of maternal undernutrition on the rat placental transcriptome: protein restriction up-regulates cholesterol transport. Genes

Background: Fetal exposure to a maternal low protein diet during rat pregnancy is associated with hypertension, renal dysfunction and metabolic disturbance in adult life. These effects are present when dietary manipulations target only the first half of pregnancy. It was hypothesised that early gestation protein restriction would impact upon placental gene expression and that this may give clues to the mechanism which links maternal diet to later consequences. Methods: Pregnant rats were fed control or a low protein diet from conception to day 13 gestation. Placentas were collected and RNA sequencing performed using the Illumina platform. Results: Protein restriction down-regulated 67 genes and up-regulated 24 genes in the placenta. Ingenuity pathway analysis showed significant enrichment in pathways related to cholesterol and lipoprotein transport and metabolism, including atherosclerosis signalling, clathrin-mediated endocytosis, LXR/RXR and FXR/RXR activation. Genes at the centre of these processes included the apolipoproteins ApoB, ApoA2 and ApoC2, microsomal triglyceride transfer protein (Mttp), the clathrin-endocytosis receptor cubilin, the transcription factor retinol binding protein 4 (Rbp4) and transerythrin (Ttr; a retinol and thyroid hormone transporter). Real-time PCR measurements largely confirmed the findings of RNASeq and indicated that the impact of protein restriction was often striking (cubilin up-regulated 32-fold, apoC2 up-regulated 17.6-fold). The findings show that gene expression in specific pathways is modulated by maternal protein restriction in the day-13 rat placenta. Conclusions: Changes in cholesterol transport may contribute to altered tissue development in the fetus and hence programme risk of disease in later life.
Influence of Lysobacter enzymogenes Strain C3 on Nematodes

Chitinolytic microflora may contribute to biological control of plant-parasitic nematodes by causing decreased egg viability through degradation of egg shells. Here, the influence of Lysobacter enzymogenes strain C3 on Caenorhabditis elegans, Heterodera schachtii, Meloidogyne javanica, Pratylenchus penetrans, and Aphelenchoides fragariae is described. Exposure of C. elegans to L. enzymogenes strain C3 on agar resulted in almost complete elimination of egg production and death of 94% of hatched juveniles after 2 d. Hatch of H. schachtii eggs was about 50% on a lawn of L. enzymogenes strain C3 on agar as compared to 80% on a lawn of E. coli. Juveniles that hatched on a lawn of L. enzymogenes strain C3 on agar died due to disintegration of the cuticle and body contents. Meloidogyne javanica juveniles died after 4 d exposure to a 7-d-old chitin broth culture of L. enzymogenes strain C3. Immersion of A. fragariae, M. javanica, and P. penetrans juveniles and adults in a nutrient broth culture of L. enzymogenes strain C3 led to rapid death and disintegration of the nematodes. Upon exposure to L. enzymogenes strain C3 cultures in nutrient broth, H. schachtii juveniles were rapidly immobilized and then lysed after three days. The death and disintegration of the tested nematodes suggests that toxins and enzymes produced by this strain are active against a range of nematode species.
Comparison of the Short-Term Risk of Bleeding and Arterial Thromboembolic Events in Nonvalvular Atrial Fibrillation Patients Newly Treated With Dabigatran or Rivaroxaban Versus Vitamin K Antagonists A French Nationwide Propensity-Matched Cohort Study

and 122 and 31 and 68 bleeding events and 33 and 58 and 12 and 28 arterial thromboembolic events were observed during follow-up, respectively. After matching, no statistically significant difference in bleeding (hazard ratio, 0.88; 95% confidence interval, 0.64–1.21) or thromboembolic (hazard ratio, 1.10; 95% confidence interval, 0.72–1.69) risk was observed between dabigatran and VKA new users. Bleeding (hazard ratio, 0.98; 95% confidence interval, 0.64–1.51) and ischemic (hazard ratio, 0.93; 95% confidence interval, 0.47–1.85) risks were comparable between rivaroxaban and VKA new users. Conclusions —In this propensity-matched cohort study, our findings suggest that physicians should exercise caution when initiating either non-VKA oral anticoagulants or VKA in patients with nonvalvular atrial fibrillation. ( Circulation 2015;132:1252-1260. 10.1161/CIRCULATIONAHA.115.015710.) VKA. In this nationwide propensity-matched cohort study (8443 dabigatran- and 4651 rivaroxaban-treated patients matched with at least 1 VKA user), no significant difference between NOAC (dabigatran or rivaroxaban) and VKA was found in terms of hospitalizations for bleeding or for arterial thromboembolic events during the early phase of therapy among new users with nonvalvular atrial fibrillation. Physicians must therefore be as cautious when initiating NOACs as when initiating VKAs, particularly in view of the absence of a NOAC antidote and objective monitoring of the extent of anticoagulation. These results are consistent with those from the few observational studies published to date and offer clinicians a more comprehensive picture of the NOAC benefit-risk balance during the early phase of treatment.
Title: Sexuality in the Lives of People with Intellectual disabilities: A Meta-Ethnographic Synthesis of Qualitative Studies

Background. The normalisation movement calls for more recognition of the sexual rights of people with intellectual disabilities to challenge classically paradoxical cultural beliefs: ‘hypersexual’ versus ‘asexual’. Aims. This meta-ethnographic qualitative synthesis aimed to explore the voices of people with intellectual disabilities in regards to their experiences and perceptions of sexuality using a Coordinated Management of Meaning framework to derive new conceptual understandings of how their sexuality exists within multiple contexts. Methods and Procedures. A systematic literature search and quality assessment yielded 16 studies that met the inclusion criteria and were synthesised following the method of meta-ethnography. Outcomes and Results. Four core themes were identified; ‘Sociocultural Norms’; ‘Under Others Power’; ‘Sexual Identity’ and ‘Sexual Experience’. Conclusions and Implications. Application of the hierarchical Coordinated Management of Meaning model suggested caregivers contextual beliefs about people with intellectual disabilities’ sexuality inhibited or facilitated positive expressions of sexuality over and above individual needs and desires. Rights-based cultural messages provided the only context that led to positive sexuality outcomes and research that explores sexuality within this context is much needed. The Coordinated Management of Meaning model identified by this research may act as a framework to support the reflective-practice of caregivers.
Re-Implementing a Dynamic Field Theory Model of Mental Maps using Python and Nengo

In Dynamic Field Theory (DFT) cognition is modeled as the interaction of a complex dynamical system. The connection to the brain is established by smaller parts of this system, neural ﬁelds, that mimic the behavior of neuron populations. We reimplemented a spatial reasoning model from DFT in Python using the Nengo framework in order to provide a more ﬂexi-ble implementation, and to facilitate future research on a more general comparison between DFT and the Neural Engineering Framework (NEF). Our results show that it is possible to recreate the DFT spatial reasoning model using Nengo, since we were able to duplicate both the behavior of single neural ﬁelds and the whole model. However, there are statistical differences in performance between the two implementations, and future work is needed to determine the cause of these differences.
An Analysis of Trends and Themes in Research Articles on Canadian Student Services

Student services professionals have emerged as significant supportive collaborators in the construction of environments that encourage student success within Canadian post-secondary education (Hardy-Cox & Strange, 2010). In Canada, literature pertaining to student services is evolving and research from other contexts is therefore often used to inform student affairs practices in this context. Yet, without a comprehensive understanding of research that is focused on Canadian student services specifically, those working in post-secondary education are left with a scope of understanding that may not always apply to the unique contexts in which they work. The purpose of this research study is to begin mapping the landscape of re search on Canadian student services. We review articles pertaining to student success, the student experience, and student services, that have been published in national ( Canadian Journal of Higher Education ) and international ( Journal of College Student Development ; Journal of College Student Retention: Research, Theory and Practice ; Journal of College Student Psychotherapy ; Journal of Student Affairs Research and Practice ; and Student Success ) student services and post-secondary education journals. This scoping review documents Canadian academic research published within the student services field and describes contributing authors and their affiliations, graduate student and post-doctoral fellow involvement, provincial and territorial research clusters, research movements over the decades, institutional research contexts, and research participants’ level of education and communities/populations, as well as contextual trends and themes.
Determination of the enantiomeric composition of amphetamine standards

Aim: From a forensic point of view, it is important to be able to discriminate between the intake of illicit (racemic mixture) and legally prescribed amphetamine (e.g. lisdexamphetamine). For the quantification of these substances, internal reference standards of d,l-amphetamine are used and the question arose whether these were in fact 1:1 racemic mixtures. Methods: Two racemic reference standards and two "enantiopure" reference standards were analyzed with a GC-MS method in full scan mode after derivatization with (R)-(-)- α -Methoxy- α -(trifluoromethyl) phe-nylacetyl chloride (R-MTPCl) to obtain diastereomers. Results and discussion: The analyses of the two racemic reference standards showed that they actually present an enantiomeric ratio of 1:1. However, the two "enantiopure" reference standards showed traces or even higher concen-trations of the other enantiomer. These traces, respectively impurities (up to 4%) could potentially cause false results when using these reference standard for calibration. Consequently, this could also affect the interpretation of the results. Conclusion: Due to the traces and impurities of the supposedly "enantiopure" reference standards available, quantification of d- and l-am-phetamine after chiral separation should be performed with a calibration using the racemic reference standards with an enantiomeric ratio of 1:1.
Contractual Complexity in Construction Projects

Building on the multifunctional perspective from current contract theory, we conceptualize contractual complexity as a three-dimensional construct to depict the explicitness and elaborateness of control, coordination, and adaptation provisions in a construction project contract. A 13-item scale with construction project features is developed for measuring the different aspects of contractual complexity following rigorous scale development procedures. Using the structural equation modeling technique, empirical testing results demonstrate that all of the three components contribute significantly to contractual complexity. Further analysis indicated that treating contractual complexity in the three-functional way outperforms the unidimensional one regarding power to explain satisfaction and strong-form opportunism.
On Whether the Size of Government Belongs in Economic Freedom Indices

Ott proposes that measures of economic freedom can be “im-proved” by ceasing to include measures of the size of government. Applying the concept of convergent validity, he shows that including size of government when measuring economic freedom yields a value of Cronbach’s alpha that he finds disturbingly low. Convergent validity and Cronbach’s alpha, which evaluate how well different measures seem to be measuring the same thing, are both taken from the broader literature on construct validity. In Ott’s analysis, lopping off the size of government yields a far improved evaluation of economic freedom indices as measuring a single thing. If it were true that we ought to lop off size of government, it would lead to a considerable shift in evaluating which countries are the most economically free. and to constructs, formative constructs. of formative
Image-Guidance in Endonasal Endoscopic Excision of Different Fibro-Osseous Pathologies of Paranasal Sinuses and Skull Base

Background: Osteoma, fibrous, dysplasia and ossifying fibroma are fibro-osseus lesions that can occur in the paranasal sinuses, management of these lesions can be technically challenging due to proximity to the orbit and skull base, with the advancement in endoscopic endonasal surgery and development of technologies such as image guidance can improve the safety of endoscopic removal and improve its safety. Illustrative cases : Three cases of fibro-ossuoes lesions are presented in this study an adult female with left frontoethmoidal osteoma, an adult male with left ethmoid fibrous dysplasia, both of whom have been treated with pure endonasal endoscopic approach with image guidance, the third case is a male child with juvenile ossifying fibroma, he was treated initially with the endoscopic approach with image guidance, but had a skull base recurrence 6 months later which was removed with an open craniotomy approach. Conclusion: Image guidance is valuable tool in improving safety and efficiency of endoscopic sinus surgery particularly in challenging cases such as fibro-osseus lesions with proximity to the skull base and orbit.