Miracle-dz/UniFAR-FTUs huggingface dataset:
Implementation of Prototype for Detection and Management of Diabetes using Android Mobile Phone Application and Rule Base System

In a research relating to identify and diagnose diseases, the pattern of disease is an important part. In that; these diseases can be identified by the various symptoms in human beings. These various symptoms identify the types of illnesses in human beings. This work is towards the identification of the diabetes. This implemented healthcare system mainly takes care of patients who suffer from chronic disease like diabetes. Such chronic patients can perform some simple self healthcare and monitoring functions via mobile phones through the implemented system to know about the circumstance of diabetes. The work embodies the development of a prototype mobile healthcare system intended to take the various symptoms in the form of questionnaire from a patient. In this research, A mobile application is developed for android devices. For diagnosis of the diabetes symptoms, different rules are defined in expert system along with the score. Using this score, symptoms of diabetes are identified and result is provided to the user. Keywords— Android OS, JSON, PHP, e-CLIPS
Deflazacort Increases Laminin Expression and Myogenic Repair, and Induces Early Persistent Functional Gain in mdx Mouse Muscular Dystrophy

Deflazacort slows the progress of Duchenne muscular dystrophy (DMD) with fewer side effects than prednisone. In mdx mice, deflazacort treatment augments repair and growth of new muscle fibers. We tested the hypothesis that deflazacort improves muscle function and promotes repair by increasing myogenic cell proliferation and fiber differentiation. mdx mice (3.5 weeks old) were treated with deflazacort (1.2 mg/kg) or vehicle for 4 weeks. Forelimb grip strength was measured. After 4 weeks, the right tibialis anterior muscle (TA) was crush injured to induce synchronous regeneration. DNA was labeled using different markers 24 and 2 h before collecting tissues 4 days after injury. The expression of creatine kinase (CK) isoforms, laminin-2 (merosin) mRNA and protein, and proliferation by myogenic cells were measured and satellite cells were identified by immunolocalization of c-met receptor. Peak grip strength increased 15% within 10 days of treatment, and was maintained up to 6 weeks after the end of treatment in a second experiment. Expression of CK MM in the regenerating TA rose from 46% to 55% of total CK activity after deflazacort treatment. Satellite cells were more numerous and appeared earlier on new fibers, in concert with a threefold increase in proliferation by myogenin+ (but not MyoD+) myoblasts. α2-Laminin mRNA expression and protein increased 1.3–5.5-fold relative to MM CK in regenerating and dystrophic TA, respectively. These studies support the hypothesis that deflazacort promotes functional gains, myogenic differentiation, myoblast fusion, and laminin expression in regenerating dystrophic muscle. The potential to augment precursor specification, strength, and possible membrane stability may be useful in directing long-term benefits for DMD patients and short-term amplification of precursors prior to myoblast transfer.
Synergistic multi‐wavelength remote sensing versus a posteriori combination of retrieved products: Application for the retrieval of atmospheric profiles using MetOp‐A

In this paper, synergy refers to a process where the use of multiple satellite observations makes the retrieval more precise than the best individual retrieval. Two general strategies can be used in order to use multi-wavelength observations in an inversion scheme. First, the multi-wavelength observations are merged in the input of the retrieval scheme. This means that the various satellite observations are used simultaneously and that their possible interactions can be exploited by the retrieval scheme. Second, each multi-wavelength observations are used independently to retrieve a same geophysical variable and then, these independent retrievals are combined a posteriori using for example a simple weighted averaging. In this paper, it is shown that the first approach provides better synergy results: The retrieval is better suited to optimize the use of all the information available because they are provided to the algorithm simultaneously. In particular, the retrieval process is able, in this case, to exploit the possible interactions between the various input information. The two retrieval approaches are tested and compared using an application for the retrieval of atmospheric profiles and integrated column quantities (temperature, water vapor, and ozone) using MetOp-A observations from IASI, AMSU-A and MHS instruments. Although real satellite observations are considered in this analysis, the results are dependent on the correlation structure in the training data set (i.e. ECMWF analysis) used to calibrate the retrieval algorithm. However, it can be seen that the infrared and microwave observations have a good synergy for the retrieval of atmospheric temperature, water vapor, and for ozone thanks to an indirect synergy. © American Geophysical Union. © 2012. American Geophysical Union. All Rights Reserved.
Antimicrobial-Resistant Campylobacter Species from Retail Raw Meats

ABSTRACT The antimicrobial susceptibilities of 378 Campylobacter isolates were determined. Resistance to tetracycline was the most common (82%), followed by resistance to doxycycline (77%), erythromycin (54%), nalidixic acid (41%), and ciprofloxacin (35%). Campylobacter coli displayed significantly higher rates of resistance to ciprofloxacin and erythromycin than Campylobacter jejuni, and Campylobacter isolates from turkey meat showed a greater resistance than those from chicken meat.
Smoking, nicotine dependence and mental health among young adults: a 13-year population-based longitudinal study.

AIMS To investigate prospectively the associations between daily smoking and nicotine dependence and anxiety, depression and suicide attempts. METHODS Data were from the Young in Norway Longitudinal Study. A population-based sample (n = 1501) was followed for 13 years from ages 13-27 years. Data were gathered on smoking patterns and nicotine dependence; and depression, anxiety and parasuicide. Extensive information on socio-demographic factors, parental and family conditions, parental rearing practices, educational career, conduct problems, alcohol problems and use of illegal substances was also collected. RESULTS Young adults who were nicotine-dependent had clearly elevated rates of anxiety, depression and parasuicide. These rates declined after controlling for a previous history of mental health problems and potential confounding factors. After adjustment, nicotine dependence was still associated with anxiety, depression and parasuicide. There was also a significant association with later depression in the group of non-dependent daily smokers. Measures of reduced mental health did not predict later smoking initiation or the development of nicotine dependence. CONCLUSIONS Mental health was reduced more seriously in nicotine-dependent smokers than in non-dependent smokers. These findings are consistent with the hypothesis that smoking, in particular nicotine dependence, influences mental health.
The results of a cementless acetabular component combined with impaction bone grafting in patients with acetabular protrusion

We undertook this study to determine the results of acetabular fixation using the Duraloc 300 uncemented acetabular component combined with impaction bone grafting in patients with acetabular protrusion. Forty-two consecutive total hip replacements using a Duraloc 300 cup in patients with acetabular protrusion requiring impaction bone grafting were reviewed at an average of 6.3 years. In no cases were structural graft, wire mesh or cages utilised. Pre-operative X-rays were analysed for degree of protrusion. Post-operative X-rays were analysed for cup placement including centre of rotation and interface gaps. Follow-up films were analysed for graft incorporation, lucent lines, osteolysis, wear and migration. Kaplan-Meier survivorship analysis was performed. All components were found to be stable. Two components moved in the immediate post-operative period, but both components stabilised within six months of surgery and have remained stable for seven and eight years respectively. Incorporation and remodelling of the bone graft occurred in all cases. Mean rate of wear was 0.19mm per year. One case of pelvic osteolysis was seen. The Duraloc 300 cup provides excellent fixation in patients with acetabular protrusion and impaction bone grafting and fixation can be achieved without the use of structural graft, wire mesh or cages. We are therefore optimistic that the durability of fixation should equal that of primary hip surgery without protrusion.
Insulin Pump Therapy in the Perioperative Period: A Review of Care after Implementation of Institutional Guidelines

Background: An institutional policy was previously established for patients with diabetes on insulin pump therapy undergoing elective surgical procedures. Method: Electronic medical records were reviewed to assess documentation of insulin pump status and glucose monitoring during preoperative, intraoperative, and postanesthesia care unit (PACU) phases of care. Results: Twenty patients with insulin pumps underwent 23 procedures from March 1 to December 31, 2011. Mean (standard deviation) age was 58 (13) years, mean diabetes duration was 28 (17) years, and mean duration of insulin pump therapy was 7 (6) years. Nearly all cases (86%) during the preoperative phase had the presence of the device documented—an improvement over the 64% noted in data collected before the policy. Intraoperatively, 13 cases (61%) had the presence of the pump documented, which was higher than the 28% before implementation of the policy. However, documentation of pump status was found in only 38% in the PACU and was actually less than the 60% documented previously. Over 90% of cases had glucose checked in the preoperative area and the PACU, and only 60% had it checked intraoperatively, which was nearly identical to the percentages seen before policy implementation. No adverse events occurred when insulin pump therapy was continued. Conclusions: Although some processes still require improvement, preliminary data suggest that the policy for perioperative management of insulin pumps has provided useful structure for care of these cases. The data thus far indicate that insulin pump therapy can be continued safely during the perioperative period.
Depth Distribution of Microbial Diversity in Mono Lake, a Meromictic Soda Lake in California

ABSTRACT We analyzed the variation with depth in the composition of members of the domain Bacteria in samples from alkaline, hypersaline, and currently meromictic Mono Lake in California. DNA samples were collected from the mixolimnion (2 m), the base of the oxycline (17.5 m), the upper chemocline (23 m), and the monimolimnion (35 m). Composition was assessed by sequencing randomly selected cloned fragments of 16S rRNA genes retrieved from the DNA samples. Most of the 212 sequences retrieved from the samples fell into five major lineages of the domain Bacteria: α- and γ-Proteobacteria (6 and 10%, respectively), Cytophaga-Flexibacter-Bacteroides (19%), high-G+C-content gram-positive organisms (Actinobacteria; 25%), and low-G+C-content gram-positive organisms (Bacillus and Clostridium; 19%). Twelve percent were identified as chloroplasts. The remaining 9% represented β- and δ-Proteobacteria, Verrucomicrobiales, and candidate divisions. Mixolimnion and oxycline samples had low microbial diversity, with only 9 and 12 distinct phylotypes, respectively, whereas chemocline and monimolimnion samples were more diverse, containing 27 and 25 phylotypes, respectively. The compositions of microbial assemblages from the mixolimnion and oxycline were not significantly different from each other (P = 0.314 and 0.877), but they were significantly different from those of chemocline and monimolimnion assemblages (P < 0.001), and the compositions of chemocline and monimolimnion assemblages were not significantly different from each other (P = 0.006 and 0.124). The populations of sequences retrieved from the mixolimnion and oxycline samples were dominated by sequences related to high-G+C-content gram-positive bacteria (49 and 63%, respectively) distributed in only three distinct phylotypes, while the population of sequences retrieved from the monimolimnion sample was dominated (52%) by sequences related to low-G+C-content gram-positive bacteria distributed in 12 distinct phylotypes. Twelve and 28% of the sequences retrieved from the chemocline sample were also found in the mixolimnion and monimolimnion samples, respectively. None of the sequences retrieved from the monimolimnion sample were found in the mixolimnion or oxycline samples. Elevated diversity in anoxic bottom water samples relative to oxic surface water samples suggests a greater opportunity for niche differentiation in bottom versus surface waters of this lake.
Patterns of comorbid inflammatory diseases in frail older women: the Women's Health and Aging Studies I and II.

BACKGROUND Developing interventions to prevent frailty in older adults is a priority as it increases the risk for disability, institutionalization, and death. Single chronic inflammatory diseases are known to increase the risk of frailty. Identification of comorbid inflammatory diseases that synergistically might heighten this risk would provide further insight into therapeutic approaches to prevent frailty. The study aims were to characterize whether there are specific inflammatory disease pairs that are associated with frailty and to determine whether the risk of frailty is affected by synergistic interactions between these inflammatory diseases. METHODS Data were from the Women's Health and Aging Studies I and II and complementary cohorts of community-dwelling women aged 70-79 years from Baltimore, Maryland (n = 620). Multivariable logistic regression analyses were performed to evaluate the relationships between these diseases and frailty. RESULTS Among the frail (11.3%), 15.2% had both depressive symptoms and anemia and 14.5% had pulmonary disease and anemia. The risk of frailty was synergistically increased in those with depressive symptoms and anemia (adjusted risk ratios = 11.93, 95% confidence interval [CI] 4.10-34.76) and those with pulmonary disease and anemia (risk ratios = 5.57, 95% CI 2.14-14.48), compared with those without either disease in each pair. The attributable proportions of frail cases due to interaction between the diseases of each pair were 0.56 (95% CI 0.07-1.05) and 0.61 (95% CI 0.18-1.05), respectively. CONCLUSIONS Synergistic interactions between specific inflammatory diseases may heighten the risk of frailty. These findings suggest that a common etiologic pathway may exist among co-occurring inflammatory diseases and that their improved comanagement may be an approach to reducing frailty.
Human embryonic development after blastomere removal: a time-lapse analysis.

BACKGROUND Blastomere biopsy of human embryos is performed for preimplantation genetic diagnosis (PGD). The impact on further development is largely unexplored, though studies on mice suggest an influence on the hatching process. The objective of this study was to evaluate the effect of blastomere biopsy on early human embryonic development using time-lapse analysis. METHODS Embryos from couples undergoing PGD treatment or IVF/ICSI were included. In the PGD group, 56 human embryos had one blastomere biopsied. As controls, 53 non-biopsied IVF/ICSI embryos were selected. All embryos were cultured until 5 days after fertilization in a time-lapse incubator (EmbryoScope™). Images of embryos were acquired every 20 min. Time-points of key embryonic events were registered, and development in the two groups was compared. RESULTS Duration of the biopsied cell-stage in the PGD group was longer than in the control group (P < 0.001), causing biopsied embryos to reach subsequent embryonic stages until hatching at significantly later time-points (P(compaction) < 0.001; P(morula) < 0.001; P(earlyblast) < 0.001; P(fullblast) = 0.01), but with unchanged intervals. Embryos in the PGD group started hatching at the same time-point as the control group, but had a smaller diameter (P < 0.001), and a thicker zona pellucida (P < 0.001) when hatching. Time-lapse videos revealed that in the control group, expansion of the blastocyst caused continuous thinning of zona pellucida until the blastocyst hatched, whereas in the PGD group the blastocyst hatched through the opening in zona pellucida artificially introduced prior to the biopsy. CONCLUSIONS We find that blastomere biopsy prolongs the biopsied cell-stage, possibly caused by a delayed compaction and alters the mechanism of hatching.
How much dose can be saved in three-phase CT urography? A combination of normal-dose corticomedullary phase with low-dose unenhanced and excretory phases.

OBJECTIVE The purpose of this study was to investigate the degree to which the total radiation dose for CT urography can be lowered by selective reduction of the dose in the unenhanced and excretory phases when images in these phases are systematically evaluated alongside normal-dose corticomedullary phase images. SUBJECTS AND METHODS Twenty-seven patients (mean age, 74±9 years) underwent single-bolus CT urography with acquisition in the unenhanced, corticomedullary, and 5-minute excretory phases. The scanning parameters for normal-dose CT urography were as follows: 16×0.75 mm, 120 kV, and automatic exposure control technique reference tube loads of 100, 120, and 100 effective mAs (mAseff). The patients also underwent low-dose unenhanced and excretory phase scanning, in which the dose was escalated stepwise from a volume CT dose index (CTDIvol) of 1.7 to 6.6 mGy (reference 20-40-60-80 mAseff). Images were analyzed for quality and diagnostic confidence. If low-dose scans of three patients were inadequate, the study continued to the next dose level. When 20 patients were successfully included in the unenhanced and excretory phase groups, the study ended. Doses were calculated with a CT patient dosimetry calculator. RESULTS Combined with the normal dose for corticomedullary phase scanning, doses of CTDIvol 1.5 mGy for the unenhanced phase and CTDIvol 2.7 mGy for the excretory phase were sufficient. The effective dose for three-phase CT urography was lowered from 16.2 to 9.4 mSv, a decrease of 42%. Diagnostic confidence in low-dose images was equal to that in normal-dose images when low-dose unenhanced and excretory phase images were read along-side normal-dose corticomedullary phase images. CONCLUSION With a three-phase CT urographic protocol, significant dose reductions in the unenhanced and excretory phases can be achieved when these phases are combined with a normal-dose corticomedullary phase.
Peripheral Arterial Disease Calf Muscle Characteristics , Strength Measures , and Mortality in Peripheral Arterial Disease

Methods At baseline, participants underwent measurement of calf muscle density with computed tomography in addition to knee extension power and isometric knee extension, plantar flexion, and hand grip strength measures. Participants were followed up annually for up to 4 years. Results were adjusted for age, sex, race, body mass index, ankle-brachial index, smoking, physical activity, and comorbidities.
The influence of locus number and information content on species delimitation: an empirical test case in an endangered Mexican salamander

Perhaps the most important recent advance in species delimitation has been the development of model‐based approaches to objectively diagnose species diversity from genetic data. Additionally, the growing accessibility of next‐generation sequence data sets provides powerful insights into genome‐wide patterns of divergence during speciation. However, applying complex models to large data sets is time‐consuming and computationally costly, requiring careful consideration of the influence of both individual and population sampling, as well as the number and informativeness of loci on species delimitation conclusions. Here, we investigated how locus number and information content affect species delimitation results for an endangered Mexican salamander species, Ambystoma ordinarium. We compared results for an eight‐locus, 137‐individual data set and an 89‐locus, seven‐individual data set. For both data sets, we used species discovery methods to define delimitation models and species validation methods to rigorously test these hypotheses. We also used integrated demographic model selection tools to choose among delimitation models, while accounting for gene flow. Our results indicate that while cryptic lineages may be delimited with relatively few loci, sampling larger numbers of loci may be required to ensure that enough informative loci are available to accurately identify and validate shallow‐scale divergences. These analyses highlight the importance of striking a balance between dense sampling of loci and individuals, particularly in shallowly diverged lineages. They also suggest the presence of a currently unrecognized, endangered species in the western part of A. ordinarium's range.
Motivating Teenagers ’ Physical Activity through Mobile Games

This paper reports the design requirements of personalized mobile persuasive games to motivate teenagers to start and continue being physically active. Being physically active can lead to reduced risks of having weight and cardiovascular problems; however efforts in this direction had variable success. Designing technology that will be engaging and motivating for teenagers requires an understanding of the factors that contribute to behavior adoption in teenagers. To understand these, we approach the design from several theoretical models: Theory of Planned Behavior, Theory of Meaning Behavior, and Personality Theory. Mobile applications can help overcome barriers to exercise, such as transportation and access to facilities. They are also personal and pervasive. Games were chosen because they are perceived to be fun by teenagers. Results from our study are summarized, as well as lessons learned and future directions of this work.
Analyzing Public Emotion and Predicting Stock Market Using Social Media

The focus of this research was to build a cloud based architecture to analyze the correlation between social media data and the financial markets. From analytical point of view this study refurbish the viability of models that treat public mode and emotion as a unitary phenomenon and suggest the needs to analyze those in predicting the stock market status of the respective companies. With the aim to justify the correlation between social media and stock market prediction process our result reveals a proportional correspondence of pubic emotion over time with the company's market viabilities. The major significance of this research is the normalization and the conversion process that has utilized vector array list which thereby strengthen the conversion process and make the cloud storing easy. Furthermore, the experimental results demonstrate its improved performance over the factor of emotion analysis and synthesizing in the process of prediction to extract patterns in the way stock markets behave and respond to external stimuli and vice versa.