Miracle-dz/UniFAR-FTUs huggingface dataset:
Prophylactic and Therapeutic EBV Vaccines: Major Scientific Obstacles, Historical Progress, and Future Direction

The Epstein-Barr virus (EBV) infects more than 95% of adults worldwide and is associated with various malignant tumors and immune diseases, imparting a huge disease burden on the human population. Available EBV vaccines are imminent. Prophylactic vaccines can effectively prevent the spread of infection, whereas therapeutic vaccines mainly stimulate cell-mediated immunity and kill infected cells, thus curbing the development of malignant tumors. Nevertheless, there are still no approved EBV vaccines after decades of effort. The complexity of the EBV life cycle, the lack of appropriate animal models, and the limited reports on adjuvant selection and immune responses are gravely impeding progress in EBV vaccines. The soluble gp350 vaccine could reduce the incidence of infectious mononucleosis (IM), which seemed to offer hope, but could not prevent EBV infection. Continuous research and vaccine trials provide deep insights into the structural biology of viruses, the designs for immunogenicity, and the evolving vaccine platforms. Moreover, the new vaccine candidates are expected to achieve further success via combined immunization to elicit both a dual protection of B cells and epithelial cells, and sustainable immunization against infected cells at several phases of infection.
Inelastic displacement ratios for evaluation of existing structures

Results of a detailed statistical study of constant relative strength inelastic displacement ratios to estimate maximum lateral inelastic displacement demands on existing structures from maximum lateral elastic displacement demands are presented. These ratios were computed for single‐degree‐of‐freedom systems with different levels of lateral strength normalized to the strength required to remain elastic when subjected to a relatively large ensemble of recorded earthquake ground motions. Three groups of soil conditions with shear wave velocities higher than 180m/s are considered. The influence of period of vibration, level of lateral yielding strength, site conditions, earthquake magnitude, distance to the source, and strain‐hardening ratio are evaluated and discussed. Mean inelastic displacement ratios and those associated with various percentiles are presented. A special emphasis is given to the dispersion of these ratios. It is concluded that distance to the source has a negligible influence on constant relative strength inelastic displacement ratios. However, for periods smaller than 1s earthquake magnitude and soil conditions have a moderate influence on these ratios. Strain hardening decreases maximum inelastic displacement at a fairly constant rate depending on the level of relative strength for periods of vibration longer than about 1.0s while it decreases maximum inelastic displacement non‐linearly as the period of vibration shortens and as the relative‐strength ratio increases for periods of vibration shorter than 1.0s. Finally, results from non‐linear regression analyses are presented that provide a simplified expression to be used to approximate mean inelastic displacement ratios during the evaluation of existing structures built on firm sites. Copyright © 2003 John Wiley & Sons, Ltd.
Solar E-Cooking with Low-Power Solar Home Systems for Sub-Saharan Africa

The e-cooking feasibility was evaluated for two of the main staple foods across rural Sub-Saharan Africa (rice and maize porridge) considering basic solar home systems (SHS) of 100–150 W and using inexpensive market available low-power DC cooking devices (rice cooker and slow cooker). The coverage of e-cooking necessities was spatially evaluated for the African continent considering households of two, five, and eight people. While households of two people were able to be covered >95% of the days, the increase in e-cooking necessities implied that only larger PV generators (150 W) located in high irradiation sites (>2400 kWh/m2/year) were able to fulfill e-cooking, even in scenarios of households of five and eight people. Furthermore, the economic cost and the greenhouse gases emission factor (GHG) of e-cooking via small SHS were evaluated and benchmarked against traditional technologies with wood and charcoal considering three-stone and improved stoves and liquefied petroleum gas (LPG) cookers. The GHG for e-cooking was 0.027–0.052 kgCO2eq. /kg·meal, which was strikingly lower than the other technologies (0.502–2.42 kgCO2eq./kg·meal). The e-cooking cost was in the range of EUR 0.022–0.078 person/day, which was clearly lower than LPG and within the range of the cost of cooking with wood and charcoal (EUR 0.02–0.48 person/day). The results provided a novel insight regarding market available technologies with a potential of changing cooking conditions in this region.
Relationship between Public Service Satisfaction and Intention of Continuous Residence of Younger Generations in Rural Areas: The Case of Jeonbuk, Korea

This study examines the population decline of younger generations in rural areas, the factors that influence the intention of continuous residence, and how these influences differ based on regional economic potential. Previous studies on intention of continuous residence lack some discussion of the role of local governments. Therefore, satisfaction with public services provided by local governments was considered as a main factor. Specifically, this study analyzed the effect of public service satisfaction on intention of continuous residence and compared this influence according to regional economic potential. This study selected respondents aged between 25 and 49 years in Jeonbuk Province, Korea. Data were collected from 980 people through an online survey, and multistage stratified sampling based on the number of residents by district and resident ages was applied to the sample design. To test the hypothesis, the study conducted a moderating effect analysis using the categorical moderator reflected by regional economic potential. The empirical analysis shows that housing support and residential environment management of public service satisfaction had positive effects on intention of continuous residence. Housing support services in particular had a stronger influence. In addition, the effect of housing support on intention of continuous residence was further strengthened in regions with low economic potential. The results of this study provide policy implications for developing countries facing a population decline in rural areas due to regional disparities between urban and rural areas.
An ultra-high data rate mass storage system

This paper describes the mechanical, electronic, and signal processing capabilities of a special purpose instrumentation mass storage system developed by Bell & Howell Datatape Division. The system is presently operational and encompasses many of the features of computer storage systems including vacuum column tape handling and fast start-stop capability. Throughput rates of up to 450 MBS and total user storage capacity of 2.9 × 1011bits are operational specifications of the system. Bit error rates of 1 × 10-9are achievable using error detection and correction techniques which complement the ENRZTMsource encoding scheme. Search speeds of up to 1140 cm/sec (450 ips) provide worst case access times of approximately four minutes to any portion of the data.
Investigation of thermal flow structure and performance heat transfer in three‐dimensional circular pipe using twisted tape based on Taguchi method analysis

In the current investigation, the twisted tape inserts are considered as the augmentation thermal technique, the influence of a variety of twisted tape configurations on pressure drop characteristics, temperature differences, thermal performance of fluid flow structure, heat transfer improvement, and friction factor are numerically evaluated. The changed geometrical parameters employed for this study comprise twisted tape width, twisted tape thickness, number of turns, and inward thickness are the input parameters. Design of experiments method is applied to analyze the influence of latter various types of geometrical parameters on hydraulic thermofluid pattern and heat transfer improvement in the twisted tube heat exchanger as the output variables. For the experimental design optimization Taguchi analysis is based on investigate of alterations and performs the orthogonal arrays (OA). Moreover, the OA L16 is chosen as the plan of experimental study. It is found the best design of twisted tape in this study by using computational fluid dynamics numerical methodology complained with Taguchi method the enhancement in heat transfer and hence the overall performance evaluation factor is higher than 1.2.
Set of new radio propagation models based on the measurements in Chinese environments

The paper gives a set of new low power radio propagation models in the picocell environments suitable to some urban and rural conditions in China. A number of propagation measurements was taken by the authors using two antenna height of 3.2 m to 7.5 m at frequency 900 MHZ. Test settings were chosen in rural open areas, suburban streets, and urban streets, crossroads and overbridges in order to study propagation in variety of environments. Based on the obtained data in different environments, this paper takes the further steps to discuss the variations of signal strength with distance that have distinct near and far regions separated by a breakpoint and the effect of antenna height and type by analyzing the two ray model, and then gives a new propagation model, which was proved well-fitted to the measured results in some places. Moreover, this model was applied to make the radio propagation prediction for CT2 Campus Network, which is now running well. This also shows the practicality and reliability of the model in Chinese environments. Up to present, the measurement database has been established and a CAD software package which can predict the radio coverage area for rural and urban in China is going to be finished.
Maternal Factors and Their Association with Patterns of Beverage Intake in Mexican Children and Adolescents

Childhood and adolescence represent critical periods where beverage and food consumption behaviors are learned and developed. Mexican mothers’ presence and influence are instrumental in shaping such behaviors. The aim of this study was to estimate the prevalence and risk associations of maternal factors for unhealthy patterns of beverage intake. This study analyzed data from a population-based cross-sectional study of healthy children and adolescents from Mexico City. Data of subject’s total water intake (TWI) and its’ sources were collected using two 24-h recall surveys. Patterns of beverage intake were constructed based on the guidance system of beverage consumption in the US. Maternal factors of interest included age, body mass index (BMI), mother’s educational level (MEL), socioeconomic status (SES), and belongingness to the paid workforce (BPW). Data of 1532 subject–mother dyads informed that 47% of subjects did not meet the Institute of Medicine (IOM) recommendations for TWI, and 94.6% showed an unhealthy beverage intake pattern, mainly consisting in a lower intake of water and a higher intake of caloric beverages with some nutrients; and calorically sweetened beverages. The major sources of hydration were caloric beverages with some nutrients (i.e., whole milk, fruit water, and flavored milk). The highest risk association for an unhealthy beverage intake pattern was seen in those subjects with mothers in the cluster with lower SES, lower MEL, lower proportion of BPW, higher BMI, and younger age (OR = 9.3, 95% CI 1.2–72.8, P = 0.03). Thus, there is a remarkably high prevalence of an unhealthy pattern of beverage intake, and specific maternal factors may be implicated as enablers of such behaviors, which is also addressable for future interventions.
High-speed 32×32 MEMS optical phased array

Optical phased arrays (OPAs) with fast response time are of great interest for various applications such as displays, free space optical communications, and lidar. Existing liquid crystal OPAs have millisecond response time and small beam steering angle. Here, we report on a novel 32×32 MEMS OPA with fast response time (<4 microseconds), large field of view (±2°), and narrow beam divergence (0.1°). The OPA is composed of high-contrast grating (HCG) mirrors which function as phase shifters. Relative to beam steering systems based on a single rotating MEMS mirror, which are typically limited to bandwidths below 50 kHz, the MEMS OPA described here has the advantage of greatly reduced mass and therefore achieves a bandwidth over 500 kHz. The OPA is fabricated using deep UV lithography to create submicron mechanical springs and electrical interconnects, enabling a high (85%) fill-factor. Each HCG mirror is composed of only a single layer of polysilicon and achieves >99% reflectivity through the use of a subwavelength grating patterned into the mirror’s polysilicon surface. Conventional metal-coated MEMS mirrors must be thick (1- 50 μm) to prevent warpage arising from thermal and residual stress. The single material construction used here results in a high degree of flatness even in a thin 400 nm HCG mirror. Beam steering is demonstrated using binary phase patterns and is accomplished with the help of a closed-loop phase control system based on a phase-shifting interferometer that provides in-situ measurement of the phase shift of each mirror in the array.
4.3: Printed, Doped Flexible P‐OLED Displays and Lighting

Add‐Vision has brought a new perspective to OLED commercialization, devices, and manufacturing, based on doped organic semiconductor device chemistries and air stable cathode technology to enable low cost printing tools and flexible, lamination encapsulation. Add‐Vision's balance of cost, performance, and form factor are enabling advantages for new printed electronics opportunities outside of conventional high resolution display applications, and complex and high capital cost processing.
Shorted T‐shaped monopole antenna for 2.4/5 GHz WLAN operation

A novel dual‐frequency shorted T‐shaped monopole antenna is proposed. The T‐shaped monopole is comprised of two horizontal arms of different lengths, which generate two separate resonant modes for the desired dual‐frequency operation, and one vertical arm is short‐circuited to a ground plane through an inverted‐L strip for good impedance matching. A prototype suited for WLAN operation in the 2.4‐ and 5‐GHz bands for a laptop as an internal antenna is constructed and tested. © 2004 Wiley Periodicals, Inc. Microwave Opt Technol Lett 41: 202–203, 2004; Published online in Wiley InterScience (www.interscience.wiley.com). DOI 10.1002/mop.20093
A transimpedance amplifier for OC-768 applications designed using a SiGe HBT BiCMOS technology

TIA's were designed with transimpedance gains of 230 /spl Omega/ and 240 /spl Omega/, with corresponding bandwidths of 30 GHz and 29 GHz, respectively. Because the simulated results in the 50 /spl Omega/ test environment match reasonably well with the measured results, it is expected that the TIA performance, when packaged with an appropriate photodiode, will improve, as the simulated results for a TIA with a photodiode indicate.
Comparative Efficacy and Tolerability of Neoadjuvant Immunotherapy Regimens for Patients with HER2-Positive Breast Cancer: A Network Meta-Analysis

This network meta-analysis addresses the need for evidence-based best-practice treatment regimens for HER2-positive breast cancer. We compared the relative efficacy and tolerability of currently available HER2-positive neoadjuvant immunotherapy regimens based on systematic searches of available randomized controlled trials (RCTs) data. Based on intention-to-treat principle, pathological complete response (pCR), overall serious adverse events (SAEs), and breast-conserving surgery (BCS) rate were analyzed using random-effect, Bayesian network meta-analysis, and standard pairwise meta-analysis. 16 RCTs (3868 patients) were included. Analyzed treatment regimens were as follows: chemotherapy+trastuzumab+pertuzumab (CTP), trastuzumab emtansine+pertuzumab (MP), chemotherapy+trastuzumab (CT), chemotherapy+pertuzumab (CP), trastuzumab+pertuzumab (TP), chemotherapy+trastuzumab+lapatinib (CTL), and chemotherapy+lapatinib (CL), and chemotherapy (C) alone. We found that, for the chance of achieving pCR, CTP was ranked first (SUCRA: 97%), followed by CTL, MP, and CT (SUCRA: 80%, 75%, and 55%, resp.). MP provided the safest regimen (SUCRA: 97%), then TP, C, and TPC (SUCRA: 82%, 76%, and 47%, resp.). CTL proved the most toxic therapy (SUCRA: 7%). No significant difference between neoadjuvant regimens was identified for BCS. Hormone receptor status did not impact ORs for pCR in any regimen. In conclusion, our findings support CTP as the optimum neoadjuvant regimen for HER2-positive breast cancer, with the best pCR and acceptable toxicity compared with CT. MP provides a therapeutic option for patients with poor performance status.
Gravity force-driven desalination unit: a sustainable energy substitute of high-pressure pumps

Water shortage is a worldwide serious issue and of great priority. Efforts are being spent to solve this issue and propose alternatives especially in arid and semiarid countries. Along with wastewater reclamation and reuse, desalination has been adopted as a non-conventional water supply alternative in water-scarce regions. Estimates report that reliance on desalinated water is expected to grow in coming decades. However, desalination requires significant amount share of generated electricity. For the time being, most of desalination plants in the Middle East are operated using non-renewable and non-environmental friendly energy options. Hence, investigations to develop effective desalination processes powered by various sustainable energies are prioritized. Thus, a low (energy)-cost seawater desalination system and methods that operate using gravity force are proposed. In this unit, the conventional high-pressure pumps are substituted by a heavy mass (water tank) to generate the pressure needed for seawater filtration (desalination using reverse osmosis membranes), resulting in a massive reduction in the energy needed (about 90%) for this process, consequently, a remarkable lowering in the cost.
Realization and dissemination of linear acceleration unit at UME

At Turkish National Metrology Institute (UME), linear acceleration unit has been realized based on laser interferometry with different signal processing techniques. Absolute calibrations of reference accelerometers are performed by using fringe-counting and minimum point method in the frequency range from 20 to 10000 Hz. Dissemination of the linear acceleration unit to the secondary levels is carried out through a comparison calibration of vibration pick-ups by "backto- back" method. Traceability chain for calibrations of the vibration calibrations and measurements performed at UME has been described in this paper.
Development of Palliative and End of Life Care: The Current Situation in Saudi Arabia

As part of the health care reforms and transformation project of the Vision 2030, a group of expert healthcare professionals was tasked with the development of a model of care for patients with life-shortening illnesses in Saudi Arabia. This Care Design Group (CDG 1-3) held a series of workshops and conducted surveys and online discussions to systematically document and develop a model of care. These interventions were aimed at achieving a national standard of care. This short article is a description of this very successful process of development.
Improving the Fatigue Resistance Of Cold Forging Tools by Fe Simulation and Computer Aided Die Shape Optimization

It is the intention of the present article to point out a new method for computer aided tool optimization as part of computer integrated tool manufacturing. Based on the results of finite element (FE) analysis and subsequent tool failure simulation, it is possible to optimize the FE model of a tool already at the stage of construction, in order to enhance the service life and process reliability. The permissible degree of freedom for any shape correction, of course, is mainly limited by constructive constraints of the tool and the properties of the material flow during the extrusion process. Thus the resulting optimized geometry has to he considered as a possible constructive alternative. However, analytical as well as practical solutions already show that a parabolical or elliptical curved surface contour, replacing a regular radius, not only improves the fatigue resistance but may have a positive influence on material flow behaviour, friction forces and resulting tool loads as well (1). The influence imposed on the material flow by the geometrical modification of the die shape will be clarified in future by the results of FE process simulation. A renewed simulation run, employing the optimized shape, may be conducted immediately after the optimization process. Along with current material research, the simulation of tool failure based on the finite element method (FEM) analysis of forging techniques (FE process simulation) therefore represents a promising direction for future developments (2–4).
The Impact of Person- Organization Fit on Job satisfaction and Turnover Intention An Applied Study on 6 October University

The present study explores the relationships between person-organization fit, job satisfaction and turnover intention empirically in the private higher education sector in Egypt, based on a survey of academic staff of October University. It has been realized that all dimensions of person –organization fit (Value congruence. Goal congruence) have positively relation with job satisfaction and negatively relation with turnover intention. Moreover, job satisfaction mediates the relationship between person organization fit and turnover intention.Finally, the survey findings suggest that; It is certain that job satisfaction will mediate the relationship between the person-organization fit and turnover intention. The person-organization fit (in terms of value and goal congruence) will provide greater importance, which will then lead individuals to a higher level of employee job satisfaction. In the long run, individuals with a higher level of job satisfaction would be less likely to leave the organization . finally It is necessary for organizations to consider the relationship between (P-O) fit, job satisfaction and turnover intention in the formulation, Developing and maintaining of their retention strategies.