Miracle-dz/UniFAR-FTUs huggingface dataset:
SIMULATION-DRIVEN OPTIMIZATION OF URBAN BUS TRANSPORT

Urban bus transport is an important mode of public transportation in developing countries and accounts for the major share of daily commuter demand in growing cities. However, many of these systems are not optimized and suffer from delays, cancellations and over-crowding, leading to losses. In recent times, intelligent transport systems (ITS) have been deployed to improve the bus operations. However, the ITS deployed in developing nations have been limited to monitoring daily operations, largely due to their dynamic and unpredictive demand pattern. Bus transport operators need new ITS solutions for schedule optimization and fleet management to improve the efficiency and profitability. Simulation driven optimization of operational parameters is one of the methods to propose the advantages of integrating ITS solutions with the bus operations. The primary data utilized for analysis includes both the static and dynamic sources. The static data consists of route, schedule, vehicle and historical ticket information. Whereas the dynamic data includes GPS traces and Automatic Vehicle Location System (AVLS) information. The simulation consists of models of bus operations as well as the passenger ridership. Each of these are inter-dependent and directly impact the measurable performance indicators for the transport operators (for example, passenger load factor, departure headways, vehicle utilization and earnings). Therefore, the goal of the proposed simulator is to optimize these measurable key performance indicators (KPI) through their iterative schedule evaluation. In this paper, the methods used to model bus transportation are investigated and the impact on measurable performance indicators are evaluated. The simulator can not only be used to optimize the schedule, but also to evaluate passenger load and bus fleet utilization scenarios. In addition to evaluation of schedule for typical urban scenario, the conditions in developing countries and application difficulties are discussed. In summary, the results indicate that demand driven scheduling results in cost savings and efficiency improvement.
EACH COMPONENT OF NEUROFILAMENT ASSEMBLES ITSELF TO MAKE COMPONENT-SPECIFIC FILAMENT

Assembly of each component of the neurofilaments from bovine brain was examined, and it was revealed that not only P 68 component but also P 200 and P 160 component make component-specific filaments. It was observed with electron microscope that P 200 made side arm like short filaments and P 160 made semilong filaments with rough surface. P 68 made very long filaments with smooth surface as already reported. The fine structures of each filament seem to be compatible with the structures predicted from the microscopic observation of the native neurofilaments and from component-specific antibody decoration study. Namely, it seems that P 200 makes side arms ofthe neurof1la-ment, and rough surface of the neurofrlament is due to P 160 ﬁlaments twisting around core filaments of P 68. These results were confirmed by centrifugal and electrophoretic methods. Recent studies on the assembly of isolated components of mammalian neurofilaments (P 200, P 160 and P 68) have shown that only main component (P 68) assembles itself to make fine filaments, but other two components (P 200 and P 160) do not assemble itself though they assemble with the P 68 component (2, 6, 15). From these results, it is suggested that P 200 and P 160 components are incorporated into the core filaments composed of P 68 component as elongation factor or accessory protein. However, there remains a possibility that these two components assemble itself under suitable conditions.
Van revisie tot implementatie: Richtlijn Diagnostiek en behandeling spastische cerebrale parese bij kinderen

Sinds 1990 zijn er belangrijke ontwikkelingen ten aanzien van diagnostiek en behandeling van deze kinderen. Behandeling van kinderen met spastische CP behoeft bij uitstek een multidisciplinaire aanpak, zowel ten aanzien van de medische als paramedische behandeling. Geheel in lijn hiermee is in samenwerking met vele disciplines betrokken bij de behandeling, in 2006 de multidisciplinaire richtlijn Diagnostiek en behandeling van kinderen met spastische cerebrale parese geschreven en vastgesteld op initiatief van de Nederlandse Vereniging van Revalidatieartsen (VRA), tevens geaccordeerd door vele beroepsverenigingen en de BOSK, de vereniging van en voor mensen met een lichamelijke handicap. Deze richtlijn bestond uit 83 uitgangsvragen gericht op de behandeling van kinderen (0-18 jaar) met spastische CP; van prognose, diagnostiek (bijvoorbeeld wanneer worden welke meetinstrumenten gebruikt), behandeling (effecten van diverse interventies op lichaamsfunctie, activiteiten of participatie), tot de informatieverschaffing aan ouders en organisatie van zorg.
Bayesian Biostatistics and Diagnostic Medicine

INTRODUCTION Introduction Statistical Methods in Diagnostic Medicine Preview of Book Datasets for Book Software References DIAGNOSTIC MEDICINE Introduction Imaging Modalities Activities in Diagnostic Medicine Accuracy and Agreement Developmental Trials for Imaging Protocol Review and Clinical Trials The Literature References OTHER DIAGNOSTIC PROCEDURES Introduction Sentinel Lymph Node Biopsy for Melanoma Tumor Depth for Diagnosis of Metastatic Melanoma A Biopsy of Non-Small Cell Lung Cancer Coronary Artery Disease BAYESIAN STATISTICS Introduction Bayes Theorem Prior Information Posterior Information Inference Sample Size Computing Exercises References BAYESIAN METHODS FOR DIAGNOSTIC ACCURACY Introduction Study Design Bayesian Methods for Diagnostic Accuracy: Binary and Ordinal Data Bayesian Methods for Test Accuracy: Quantitative Variables Clustered Data Comparing Accuracy between Modalities Sample Size Determination Exercises References REGRESSION AND TEST ACCURACY Introduction The Audiology Study The ROC Curve and Patient Covariates Exercises References AGREEMENT Introduction Agreement for Discrete Ratings Agreement for a Continuous Response Combining Reader Information Exercises References DIAGNOSTIC IMAGING AND CLINICAL TRIALS Introduction Clinical Trials The Protocol Guidelines for Tumor Response Bayesian Sequential Stopping Rules Software for Clinical Trials Examples Exercises References OTHER TOPICS Introduction Imperfect Diagnostic Test Procedures Test Accuracy and Survival Analysis ROC Curves with a Non-Binary Gold Standard Periodic Screening in Cancer Decision Theory and Diagnostic Accuracy Exercises References
Smoking Cessation/Prevention in the Air Force: How Adequate

Abstract : It is widely held that tobacco is a cause of cancer and other debilitating illnesses. Public policy restricting sales and uses of the product everywhere, even in tobacco growing regions of the country, underscores the seriousness of this belief. Recently, one of the major tobacco companies has come forth and admitted that tobacco is a health hazard. The purpose of this study is to determine if healthcare providers in the military adequately address tobacco related ailments and smoking cessation programs with their clients. This study focused on what happens at the primary point of contact between military healthcare providers and clients. A retrospective chart review of a random sample of charts and client interview was employed to compare providers documented practice protocols with established guidelines set by the Department of Defense (DoD) for implementation of smoking cessation programs in the military. The study was conducted to determine how well military providers met the guidelines. An Intervention Plan Documentation checklist constructed by the researcher, and evaluated by a panel of two experts for content validity in smoking cessation practices was utilized. A pilot study was done to determine intercoder reliability. Descriptive statistics were utilized to determine whether health care providers in the military organization were promoting a tobacco free lifestyle and preventing smoking related health problems as evidenced by the documentation in client charts. Findings showed that military providers were having dialogue with their clients about smoking cessation. However, documentation of this intervention was not always complete.
Effective Strategies to Assist Spouses of Junior Enlisted Members with Employment. Analysis of the 1997 Survey of Spouses of Enlisted Personnel.

Abstract : The Army, Navy, Marine Corps, and Air Force each offer separate yet similar spouse employment assistance programs (EAPs). To evaluate these programs, and to provide a demographic and employment-related profile of spouses of junior enlisted members, the Defense Manpower Data Center conducted a survey of non-military spouses of military members in paygrades E5 and below. The survey found that two thirds of spouses of military members in paygrades E5 and below at least occasionally experienced difficulty making ends meet. Most of these spouses wanted or needed to work, usually at least in part to save money for the future and to get money for basic expenses. Thus motivated, many spouses quickly sought and found employment at their new locations despite such barriers as difficulty finding affordable child care. However, the majority of spouses in the employment market did not find a job that made much use of their skills and training. Very few spouses found their jobs through the EAP. Among spouses who were working, wanting to work, or seeking employment, a majority did not know of EAP services in the area in which they currently lived.
The Effects of Collaborative-Â­‐Care Training on Paraprofessional Case Managers' Perceived Self-Â­‐Efficacy, Knowledge, and Behaviors for Depression-Â­‐Related Services Delivery

Author(s): Landry, Craig M. | Advisor(s): Jackson, Aurora P | Abstract: Depression is one of the leading causes of disability in the world and affects about 10 percent of adults in the United States. Under-resourced communities of color often have low access to professional providers of evidence-based depression care. The purpose of this dissertation was to compare the effectiveness of a community engagement intervention across social service agencies relative to a more traditional technical assistance based training implementation strategy on participation in training and delivery of collaborative depression care by paraprofessional case managers in two low-income communities in Los Angeles. The direct effects of training participation versus no participation under both intervention conditions on depression care services delivery by paraprofessional case managers was also evaluated. Case managers in agencies assigned to the intensive training condition (experimental group) were more likely than their counterparts in agencies assigned to the technical-assistance-only control group to participate voluntarily in the training sessions at their agencies. They also were more likely to score higher at posttest on measures of use of evidence-based problem-solving strategies, use of depression-oriented outreach activities, and amount of time spent delivering direct depression care services. No significant differences were found with regard to knowledge about depression, attitudes toward people with depression, and perceived barriers to providing depression services. The conclusion addresses the results broadly and suggests some implications for policy, practice, and future research.
Maya Medicine: Traditional Healing in Yucatán

This account of the practice of traditional Maya medicine examines the work of curers in Piste, Mexico, a small town in the Yucatan Peninsula near the ruins of Chichen Itza. The traditions of plant use and ethnomedicine applied by these healers have been transmitted from one generation to the next since the colonial period throughout the state of Yucatan and the adjoining states of Campeche and Quintana Roo. In addition to plants, traditional healers use western medicine and traditional rituals that include magical elements, for curing in Yucatan is at once deeply spiritual and empirically oriented, addressing problems of the body, spirit, and mind. Curers either learn from elders or are recruited through revelatory dreams. The men who learn their skills through dreams communicate with supernatural beings by means of divining stones and crystals. Some of the locals acknowledge their medical skills; some disparage them as rustics or vilify them as witches. The curer may act as a doctor, priest, and psychiatrist. The book traces the entire process of curing.
Older adults' misuse of alcohol, medicines, and other drugs : research and practice issues

It includes a useful review of medical manifestations of alcoholism; techniques on how to detect early versus late onset of alcoholism; and treatment alternatives for alcohol abusers. It also focuses on prescriptive and illicit drug abuse. The topics include misuse of prescription drugs; interactions between alcohol and drugs; and drug misuse in nursing homes.
Considerations of Identity in L2 Learning

• Identity is constituted through and by language. (p.895) • Within sociocultural approaches, identity is theorized as a contingent process involving dialectic relations between learners and the various worlds and experiences they inhabit and which act on them. (p.895) • In SLA and Applied linguistics research, attribution of group-based, ethnic characteristics has tended to perpetuate difference in negative terms vis-à-vis Western, and especially Anglo-American, norms and expectations. Therefore, characterizations of students are likely to be more harmful than helpful to language educators. (p.896)
Implementing CalWORKs Support Services: Child Care in Los Angeles County

The welfare system in the United States is embarking on a major transition. Aid to Families with Dependent Children (AFDC), an entitlement program enabling low-income parents to stay home with their children, has been replaced with Temporary Assistance to Needy Families (TANF), a time-limited benefit that requires parents to work or participate in work-related activities as a condition of aid receipt. If parents are to meet work requirements, they must have access to child care services. Yet the cost of care or an insufficient supply of child care providers could limit child care accessibility. In this report, I evaluate Los Angeles County’s plan to assist recipients in securing child care services.
Lower Extremity Disorders among Men and Women in Army Basic Training and Effects of Two Types of Boots

Abstract : This study was conducted to determine the nature and the frequency of lower extremity disorders incurred by men and women undergoing Army basic training and to analyze the differential effects of two types of combat boots on lower extremity disorders. The feet and lower legs of 2,074 men and 767 women were examined by medical personnel prior to the initiation of training and on three other occasions over the eight weeks of training. The data from these examinations were augmented by the diagnoses and case dispositions associated with sick call visits for lower extremity problems. It was found that the rates of occurrence of blisters and lace lesions were higher among the test participants who wore hot weather boots than among those who wore black leather boots. Of 27 types of lower extremity disorders diagnosed among the participants, two were incurred only by men and two only by women. The remaining disorders were identified in both sexes and statistical analyses revealed that 12 of these disorders were experienced by a significantly higher proportion of women than men. None of the disorders diagnosed in both sexes were incurred by a significantly higher proportion of men than women. The number of sick call visits and duty restrictions for lower extremity problems were also analyzed as a function of gender and boot type.
* Clinica Neurologica I dell'Universith di Milano ** Dz~d~ione di Neurologia, Fondazione Clinica del Lavoro - Centro Medico di Riabilitazione, Veruno (NO)

The hypothesis to be verified is that the cognitive defects in nondemented and nondepressed Parldnsonians are due solely to a bilateral nigrostriatal disorder that causes motor slowing. It was tested on 26 mildly disabled patients with idiopathic Parldnson disease optimally controlled with L-Dopa, nondemented and nondepressed and not receiving anticholinergic. The test used was a simplified version of the London Towers Test of problem-solving ability, designed to measure a facet of prefrontally-induced bradyphrenia, already calibrated on 131 healthy subjects. The results revealed no significant difference between the ParIdnsonians and controls, thus providing no support for the hypothesis in question.
Keeping Time: Implementing Appointment-based Family-centered Rounds

Background: Family-centered rounds (FCRs) provide many benefits over traditional rounds, including higher patient satisfaction, and shared mental models among staff. These benefits can only be achieved when key members of the care team are present and engaged. We aimed to improve patient engagement and satisfaction with our existing bedside rounds by designing a new FCR process. Methods: We conducted a needs assessment and formed a multidisciplinary FCR committee that identified appointment-based family-centered rounds (aFCRs) as a primary intervention. We designed, implemented, and iteratively refined an aFCR process. We tracked process metrics (rounds attendance by key participants), a balancing metric (time per patient), and outcome metrics (patient satisfaction domains) during the intervention and follow-up periods. Results: After implementing aFCR, 65% of patients reported positive experience with rounds and communication. Rounds duration per patient was similar (9 versus 9.4 min). Nurse, subspecialist, and interpreter attendance on rounds was 72%, 60%, and 90%, respectively. We employed a Rounding Coordinator to complete the scheduling and communication required for successful aFCR. Discussion: We successfully improved our rounding processes through the introduction of aFCR with the addition of a rounding coordinator. Our experience demonstrates one method to increase multidisciplinary team member attendance on rounds and patient satisfaction with physician communication in the inpatient setting.
PENGARUH KARAKTERISTIK SELEBRITI ENDORSER TERHADAP MINAT BELI MELALUI KESADARAN MEREK HOTEL DI INSTAGRAM

Penggunaan selebriti endorser di Instagram sebagai alat pemasaran hotel menjadi semakin populer. Tujuan dari penelitian ini adalah untuk mengetahui pengaruh karakteristik selebriti endorser di Instagram terhadap minat beli melalui kesadaran merek hotel. Penelitian ini melibatkan sebanyak 304 pengikut dari tiga selebriti endorser. Hasil penelitian menunjukkan bahwa karakteristik selebriti endorser memiliki pengaruh yang positif dan signifikan terhadap minat beli melalui kesadaran merek. Akan tetapi, pengaruh langsung dari karakteristik selebriti endorser terhadap minat beli lebih besar dibandingkan jika harus melalui kesadaran merek terlebih dahulu
The influence of shift work and menstrual cycle phase on depression and other symptonms reported by female nurses

The purpose of this study was to examine whether working night shifts has health consequences for female nurses and whether these consequences vary according to the phase of the menstrual cycle of the subjects. Both shift work and the premenstrual phase of the menstrual cycle have been found to produce a variety of symptoms, particularly depression, in women. The present study measured a series of symptoms with the Premenstrual Assessment Form, a questionnaire widely used for the assessment of premenstrual syndromes, and the Beck Depression Inventory on a sample of 26 female nurses. Repeated measures were taken weekly over a period of six weeks. The kesults show consistently higher endorsement of symptoms in a group of nurses who worked on rotating shifts compared with a group which worked only days. This effect was strongly related to the immediate consequences of working a night shiftThere was an interactive effect between shift work and menstrual cycle which rendered women who work rotating shifts more vulnerable to depression premenstrually compared with the control group. This type of interaction was not found for the other symptoms examined. The results were discussed in terms of theoretical and practical implications,
A novel method for the selective elimination of HIV infected cells: dexamethasone and procaine as a combination therapy prototype

It has been established that various combinations of three or more antiretroviral drugs will lead to durable inhibition of HIV replication in patients. Despite its success in controlling the infection, highly active antiretroviral therapy (HAART) does not eradicate the virus; systemic infection re-emerges upon treatment interruption in all but exceptional cases, necessitating a lifetime of expensive drug therapy with an ever-present risk of emerging drug resistance. Thus, there is a critical need for the development of new treatment modalities not based solely on virally-encoded targets, and with the potential to actually cure HIV infection. Using standard colorimetric and fluorometric live/dead cell labeling methods, we have developed a novel "selective cell death" assay, and identified a lead drug combination for elimination of infected cells, involving a patented combination of 2 generic FDA approved drugs or their metabolites: the glucocorticoid dexamethasone (Dex) and N,N-diethylaminoethanolamine (DEAE, a metabolite of procaine). Neither drug alone, but only the combination, is effective in cell killing, and only in HIV-infected cells (P<0.0001). Furthermore, prolonged exposure of cells to this drug combination leads to a decline in viral load; two weeks of treatment results in a decrease of more than 50% relative to untreated control cells. Flow cytometric methods indicate that the mechanism of infected cell death is via apoptosis. In addition, microray analysis has highlighted several host genes whose expression is altered by Dex/DEAE treatment, providing initial clues to understanding the pathways leading to apoptosis in infected cells.
Autonomous readers: the impact of news customisation on audiences’ psychological and behavioural outcomes

ABSTRACT Customisation features on news websites and apps provide news readers with increased control over their reading experience by allowing them to choose what they can read next. This study investigated how two types of news customisation features could influence news readers’ need satisfaction for autonomy, news enjoyment, news engagement and intrinsic motivation to continue reading with two experiments. The findings of experiment 1 (n = 47) showed that news readers experienced greater need satisfaction for autonomy and spent more time reading news stories when the stories were provided through customisation features compared to the control condition (non-customisation). Experiment 2 (n = 92) found that participants’ intrinsic motivation to read increased when the stories were presented through the simple customisation feature compared to the no customisation feature. Further, news readers’ locus of control types (internal or external) was found to moderate the effect of the customisation feature on perceived engagement.