Miracle-dz/UniFAR-FTUs huggingface dataset:
Atypical resting synchrony in autism spectrum disorder

Autism spectrum disorder (ASD) is increasingly understood to be associated with aberrant functional brain connectivity. Few studies, however, have described such atypical neural synchrony among specific brain regions. Here, we used magnetoencephalography (MEG) to characterize alterations in functional connectivity in adolescents with ASD through source space analysis of phase synchrony. Resting‐state MEG data were collected from 16 adolescents with ASD and 15 age‐ and sex‐matched typically developing (TD) adolescents. Atlas‐guided reconstruction of neural activity at various cortical and subcortical regions was performed and inter‐regional phase synchrony was calculated in physiologically relevant frequency bands. Using a multilevel approach, we characterized atypical resting‐state synchrony within specific anatomically defined networks as well as altered network topologies at both regional and whole‐network scales. Adolescents with ASD demonstrated frequency‐dependent alterations in inter‐regional functional connectivity. Hyperconnectivity was observed among the frontal, temporal, and subcortical regions in beta and gamma frequency ranges. In contrast, parietal and occipital regions were hypoconnected to widespread brain regions in theta and alpha bands in ASD. Furthermore, we isolated a hyperconnected network in the gamma band in adolescents with ASD which encompassed orbitofrontal, subcortical, and temporal regions implicated in social cognition. Results from graph analyses confirmed that frequency‐dependent alterations of network topologies exist at both global and local levels. We present the first source‐space investigation of oscillatory phase synchrony in resting‐state MEG in ASD. This work provides evidence of atypical connectivity at physiologically relevant time scales and indicates that alterations of functional connectivity in adolescents with ASD are frequency dependent and region dependent. Hum Brain Mapp 35:6049–6066, 2014. © 2014 Wiley Periodicals, Inc.
An Enhanced SRAM BISR Design with Reduced Timing Penalty

Redundancy repair is an effective yield-enhancement technique for memories. There are many previously proposed repair methodologies, such as the popular repair methodology based on the concept of address remapping mechanism achieved by address comparison and address reconfiguration. However, a BISR design with a typical address remapping mechanism usually involves significant timing penalty. Therefore, we propose a new address remapping scheme with a write buffer to reduce the timing penalty. Our experiments show that with the proposed address remapping scheme and redundancy architecture, the timing penalty of our BISR scheme is the same with that of the built-in self-test (BIST) circuit-only one multiplexer delay for both the inputs and outputs
A personalized semantic portal for enhanced user support

Although many advances have been made in semantic portal research, often links to relevant pages are not shown and the same content/links are presented to users that have different background and interests. This paper introduces a novel semantic portal, SEMPort, to support the browsing of users based on personalization and enriched semantic hyperlinks. Our semantic portal makes a novel contribution by integrating adaptive hypermedia methods and enriched semantic hyperlinks into semantic portal technologies to provide better navigation. SEMPort supports different personalization such as adaptive link sorting and adaptive link annotation based on interests of individual users. Enriched semantic links are also supplied to guide users to relevant pages. In addition, easy-to-use and real-time content maintenance mechanisms are provided, which is important for the evolution of the content. Evaluations carried out to assess the semantic portal include performance evaluations, interface usability using Nielsen's heuristics and empirical user studies. This paper also provides an overview and comparison to the state-of-the-art as well as outlining future directions for semantic portals.
Behavior rating inventory for moderately, severely, and profoundly retarded persons.

The reliability and validity of the behavior of a sample of institutionalized mentally retarded children, with total IQs between 2 and 53, were assessed by a new scale measuring the following areas; communication, self-help, physical skills, self-control, and social behavior. Clinically and statistically acceptable levels of interrater agreement were found. With respect to validity: (a) several factors loaded very highly on items consistent with the a priori labeling of subscales; (b) two of the factors (cognitive and psychomotor development) could account for about 75% of the explained variance in ward placement levels (multiple R = .86); and (c) individual items on the Behavior Rating Inventory for the Retarded correlated highly with independently derived measures of the actual behavior these items represented. The major advantages of this scale over existing ones include its clearly demonstrated validity and relative ease of administration and scoring.
Cyanide inactivation of hydrogenase from Azotobacter vinelandii

The effects of cyanide on membrane-associated and purified hydrogenase from Azotobacter vinelandii were characterized. Inactivation of hydrogenase by cyanide was dependent on the activity (oxidation) state of the enzyme. Active (reduced) hydrogenase showed no inactivation when treated with cyanide over several hours. Treatment of reversibly inactive (oxidized) states of both membrane-associated and purified hydrogenase, however, resulted in a time-dependent, irreversible loss of hydrogenase activity. The rate of cyanide inactivation was dependent on the cyanide concentration and was an apparent first-order process for purified enzyme (bimolecular rate constant, 23.1 M-1 min-1 for CN-). The rate of inactivation decreased with decreasing pH. [14C]cyanide remained associated with cyanide-inactivated hydrogenase after gel filtration chromatography, with a stoichiometry of 1.7 mol of cyanide bound per mol of inactive enzyme. The presence of saturating concentrations of CO had no effect on the rate or extent of cyanide inactivation of hydrogenases. The results indicate that cyanide can cause a time-dependent, irreversible inactivation of hydrogenase in the oxidized, activatable state but has no effect when hydrogenase is in the reduced, active state.
Autism and Auditory Brain Stem Responses

Objective To study a controversy that has been discussed for more than two decades: whether or not children with autism have abnormalities affecting the cochlear nerve or the auditory pathway in the brain stem and, if so, to describe these abnormalities. Design A group of 153 children and adolescents with autistic disorder were included in an investigation of auditory brain stem responses (ABR). Two thirds of this group, 101 individuals (75 boys, 26 girls), had normal hearing and they were selected for an in-depth ABR study. The results from the study group were compared with those of an age-matched comparison group. Results The III-V interpeak latency (IPL) was significantly prolonged in both boys and girls with autism, compared with the controls. The latencies of ABR waves I and V were also significantly lengthened in the study groups. The individual test results showed that more than half of this normal-hearing autistic disorder group (58%) had abnormalities of one or more of eight ABR parameters studied. The most common abnormalities were prolongation of wave V (38%), and of I-V IPL (28%). A lengthening of the I-V IPL was also recorded in 27% of 49 children who were difficult to test or who had hearing loss. Abnormal left–right differences of ABR latencies were found in 18% of autism cases with normal hearing. Conclusions Possible causes of the reported ABR abnormalities, observed here as well as in other studies, are discussed. Brain stem lesion, occult cochlear dysfunction, and involvement of the cochlear efferent system are probable factors that can explain the ABR findings
Biogeography of Actinomycete Communities and Type II Polyketide Synthase Genes in Soils Collected in New Jersey and Central Asia

ABSTRACT Soil microbial communities are believed to be comprised of thousands of different bacterial species. One prevailing idea is that “everything is everywhere, and the environment selects,” implying that all types of bacteria are present in all environments where their growth requirements are met. We tested this hypothesis using actinomycete communities and type II polyketide synthase (PKS) genes found in soils collected from New Jersey and Uzbekistan (n = 91). Terminal restriction fragment length polymorphism analysis using actinomycete 16S rRNA and type II PKS genes was employed to determine community profiles. The terminal fragment frequencies in soil samples had a lognormal distribution, indicating that the majority of actinomycete phylotypes and PKS pathways are present infrequently in the environment. Less than 1% of peaks were detected in more than 50% of samples, and as many as 18% of the fragments were unique and detected in only one sample. Actinomycete 16S rRNA fingerprints clustered by country of origin, indicating that unique populations are present in North America and Central Asia. Sequence analysis of type II PKS gene fragments cloned from Uzbek soil revealed 35 novel sequence clades whose levels of identity to genes in the GenBank database ranged from 68 to 92%. The data indicate that actinomycetes are patchily distributed but that distinct populations are present in North American and Central Asia. These results have implications for microbial bioprospecting and indicate that the cosmopolitan actinomycete species and PKS pathways may account for only a small proportion of the total diversity in soil.
Di-Ras, a Distinct Subgroup of Ras Family GTPases with Unique Biochemical Properties*

The small GTPase Ras family regulates a variety of cell functions including proliferation and differentiation. Here we have identified novel Ras members, human Di-Ras1 and Di-Ras2, belonging to a distinct branch of the GTPase family. Di-Ras1 and Di-Ras2 specifically expressed in heart and brain share 30–40% overall identity with other members of Ras family, however, they have the following characteristic substitutions at highly conserved regions among the Ras family. 1) Thr-63 and Ser-65 in Di-Ras are substituted for Ala-59 and Gln-61 positions in Ha-Ras, respectively, that are known to be critical for GTP hydrolysis. 2) Within the effector domains, Di-Ras has Ile at a position corresponding to Asp-33 in Ha-Ras, which is important for its interaction with the downstream effector Raf. As predicted by these substitutions, Di-Ras has only a quite low level of GTPase activity and exists predominantly as a GTP-bound form upon its expression in living cells. Moreover, Di-Ras fails to interact with the Ras-binding domain of Raf, resulting in no stimulation of mitogen-activated protein kinase. Interestingly, introduction of Di-Ras into HEK293T cells induces large cellular vacuolation. These findings raise the possibility that Di-Ras might regulate cell morphogenesis in a manner distinct from other members of Ras family.
The Tome of Secure Compilation: Fully Abstract Compilation to Protected Modules Architectures ; Het boek van veilige compilatie: Volledig abstracte compilatie naar beschermende modulearchitecturen

Mature manhood: that means to have rediscovered the seriousness one had as a child at play. Friedrich Nietzsche Beyond Good and Evil Part IV Aphorism 94 A compiler is a complex software artefact that, among other things, translates programs written in a source-level language into programs written in a targetlevel one. Source-level programming languages often provide programmers with means to define and enforce security policies. However, this does not always hold for target languages, so compilers do not always have the means to translate secure source programs into secure target programs. When security policies are not preserved by a compiler during the language translation, the generated target-level code can be subject to malicious security-breaching attacks. When security is preserved by a compiler, however, source-level security policies cannot be violated in the generated target-level code. A compiler that preserves sourcelevel security policies in the target-level programs it generates is called a secure compiler. This thesis then presents a secure compiler from an object-oriented Javalike language to untyped assembly code extended with protected module architectures (PMA) – an isolation mechanism of modern processors. To prove that compiler secure, it is proven to be fully abstract, so it preserves (and reflects) the behaviour of the programs it compiles. Since the behaviour of programs captures also the security policies of that program, a fully abstract compiler is a secure one. This thesis also studies the behaviour for untyped assembly code extended with PMA in terms of trace semantics. Two such trace semantics are developed in
Classification of Fake and Real Articles Based on Support Vector Machines Language and Statistics Spring 2013

Fake or real? That is the question, even in the context of languages. In this course project, we are given the task of distinguishing real Broadcast News articles from fake “articles” generated by a trigram model trained from the 100 million word corpus of Broadcast News articles from 1992–1996. This task is clearly not difficult for humans, while machines are not as smart as us to tell whether the articles make sense at higher levels such as semantics. In this report we presented a machine-oriented solution based on Support Vector Machines [1] to classify between fake and real articles. Features deployed in our task covered various aspects of languages. For example, we tried n-gram language models and parsers to generate features that capture the local dependencies and syntactical information of the texts in the data sets. The topic model based on Latent Dirichlet Allocation (LDA) [2] was used in an attempt to distinguish the articles at the semantic level. With all these features and a good classifier (namely SVM), we hope to design a program that is capable of discovering the deficiencies in the conventional trigram language model and therefore discriminating between fake and real articles.
Load forecasting on demand side by multi-regression model for operation of battery energy storage system

The load forecasting of the electric power has been studied extensively in the world. In many cases, the load forecast of the electric power systems is studied in the electric power company rather than demand side. The load forecast in the demand side is affected by some specific factors that are not measured and expected in advance. Although the factors/parameters are limited, it was difficult to build standard models that are applicable to various demand sides. In the era of deregulation, however, the management of customers' load became more important. Moreover, the demand forecast with high accuracy is necessary for the proper operation of BESS (battery energy storage system) such as NAS battery. In this paper a load forecasting technique using multi-regression model is proposed. Based on five years' records of the load in a university campus, the load for tomorrow can be forecasted. Numerical tests demonstrate the robustness and accuracy of the proposed technique.
A Concept-Based Approach to Retrieval from an Electronic Industrial Directory

The success of local economies has become increasingly dependent on participation in the global economy. The development and convergence of computer and communication technologies have made it technically and economically feasible for a small business to be active at a global level. The issue is developing mechanisms to ensure this can take place. In this paper we introduce an Electronic Industrial Directory (EID) prototype-a database and the means to retrieve information from it-to enable businesses to find potential suppliers or purchasers with whom they may do business. We present a conceptual model of the EID and discuss the design of each subsystem. Specifically, to differentiate our model from the conventional word-based retrieval methods employed in most of the Yellow Pages-like systems, we propose a concept-based matching scheme for industry class identification as well as for product/service comparison during the retrieval process. We believe that retrieval effectiveness will be increased with the introduced model. In addition, visual navigation is supported in the query-reformulation process with the aim of providing maximum ease of searching for novice users.
Telehealth interventions for the secondary prevention of coronary heart disease: a systematic review

Coronary heart disease (CHD) is a leading cause of death globally. Despite proven health benefits and international recommendations, attendance at cardiac rehabilitation programs is poor. Telehealth (phone, Internet, and videoconference communication between patient and health-care provider) has emerged as an innovative way of delivering health interventions. This review aimed to determine telehealth effectiveness in CHD management. Study design includes systematic review with meta-analysis. Randomized controlled trials evaluating telehealth interventions in patients with CHD were identified by searching multiple electronic databases, reference lists, relevant conference lists, gray literature, and key-word searching of the Internet. Studies were selected if they evaluated a telephone, videoconference, or web-based intervention, provided objective measurements of mortality, changes in multiple risk factor levels or quality of life. In total, 11 trials were identified (3145 patients). Telehealth interventions were associated with nonsignificant lower all-cause mortality than controls [relative risk = 0.70, 95% confidence interval (CI) = 0.45-1.1; P = 0.12]. These interventions showed a significantly lower weighted mean difference (WMD) at medium long-term follow-up than controls for total cholesterol (WMD = 0.37mmol/l, 95% CI = 0.19-0.56, P < 0.001), systolic blood pressure (WMD = 4.69 mmHg, 95% CI = 2.91-6.47, P < 0.001), and fewer smokers (relative risk = 0.84, 95% CI = 0.65-0.98, P = 0.04). Significant favorable changes at follow-up were also found in high-density lipoprotien and low-density lipoprotein. In conclusion, telehealth interventions provide effective risk factor reduction and secondary prevention. Provision of telehealth models could help increase uptake of a formal secondary prevention by those who do not access cardiac rehabilitation and narrow the current evidence-practice gap.
[Study on the current status and trend of food consumption among Chinese population].

OBJECTIVE To describe the current status and trend of food consumption among Chinese residents. METHODS 23,470 households including 68,962 subjects were randomly sampled from 132 counties in 31 provinces, autonomous regions and municipalities. A 24-hour dietary recall method for 3 consecutive days was used to collect information on food intake, but the condiment intake was collected by weighting method. RESULTS The average food consumption per reference man per day of Chinese people included 402 g (urban/rural: 366 g/ 416 g) cereals; 276 g (urban/rural: 252 g/ 286 g) vegetables; 45 g (urban/rural:69 g/36 g) fruits; 79 g (urban/rural: 105 g/69 g) meats; 30 g (urban/rural:45 g/24 g) fishery products; 24 g (urban/rural: 33 g/20 g) eggs; 27 g(urban/rural: 66 g/ 11 g) dairy; 16 g legume; 42 g (urban/rural:44 g/41 g) edible oil; 12 g (urban/rural: 11 g/12 g) salt; 9 g (urban/rural: 11 g/8 g) soy sauce. CONCLUSIONS For Chinese residents, the quality of diet had been improved and consumptions of animal products, milk, and edible oil had been increased, but the consumptions of dairy and legume products intake was still low which called for improvement. The unbalance was characterized as the downward trend in cereal, vegetable and fruit consumption but significant increased in animal products and oil intake among urban people. Dietary pattern of some subjects adopted a "high energy density" diet. Double burdens from under-nutrition and over-nutrition should both be considered as problems which asked for attention by the government and researchers.
Power distribution in RES-Diesel autonomous power system with doubly fed induction generator for reduction of fuel consumption

A renewable energy system RES with cooperation of diesel driven autonomous doubly fed induction generator is presented in the paper. The analysis takes into consideration the power system, where the main power source is a variable speed diesel engine, which operates in full range of power consumption. The RES source is used for diesel engine fuel reduction. The paper presents power distribution between the two sources during supply of isolated load. Reduction of fuel consumption by the use of variable speed operation of diesel engine is also discussed. The issue of energy storage ESt cooperation with RES- diesel power generation system is evaluated. Simulation results of described system are obtained using PSIM simulation software and they are presented in the paper.
Fusion of Multiple Representations and Using HMM Classifier for Improving Palmprint Identification

An accurate automatic personal identification is critical in a wide range of application domains such as access control and surveillance systems. Biometrics technologies have been increasingly adopted to provide identification with a high degree of confidence. A number of biometric traits exist and are in use in various applications. As one of the developing biometric techniques, palmprint identification is becoming a popular and convincing solution for identifying persons’ identity since palmprint is proved to be a unique and stable personal physiological characteristic. In this paper, two representations of the unique palmprint are integrated in order to construct an efficient multimodal identification system. For that, the two feature vectors are extracted and used for training two different classifiers. Thus, for each palm image, tow feature extraction techniques are used, these are: 2D Block based Discrete Cosine Transform (2D-BDCT) and 2D CoNtourlet Transform (2D-CNT). Subsequently, the two feature vectors have been modeled as Hidden Markov Model (HMM). The two sub-systems outputs are fused at the matchingscore level. The experimental results showed that the designed system achieves an excellent identification rate and provide more security than unimodal biometric-based system. Keywords—Biometrics, identification, Palmprint, HMM, 2DBDCT, Contourlet, Data fusion.
DO BADANIA ZASI Ę GU WIDOCZNO Ś CI PANORAM USING A MODEL OF VIRTUAL CITY FOR RESEARCH ON VISIBILITY RANGE OF PANORAMAS OF THE CITY

Virtual three-dimensional spatial models of cities become more general. They can be an instrument along with their proper methodologies of utilization on multithreaded analysis of spatial structure of cities. It enables better and conscious creation of development of urban areas. An analytic computer method of coverage of visibility of panoramas will be presented in the hereby article. It can be helpful in process of proper formulating planning directions of protection and creating the city views.
Comparative study of nasopharyngeal aspirate and nasal swab specimens for detection of influenza

The neuraminidase inhibitors zanamivir and oseltamivir have been shown to be effective in the treatment of influenza A and B viral infections. Both of these drugs are ineffective against respiratory infections caused by other microbes. Although the onset of influenza is often abrupt with prominent systemic features, the clinical spectrum of this disease is extremely broad and it cannot be reliably distinguished from other respiratory infections on clinical grounds alone.1 To help them decide which patients will benefit from the new treatments for influenza doctors therefore need rapid and sensitive point of care tests to verify the cause of the infection. A nasopharyngeal aspirate is generally considered the best specimen for detection of …