Miracle-dz/UniFAR-FTUs huggingface dataset:
Principle of a multi-load/single converter system for low power induction heating

The induction heating appliances used for cooking generally include two or four inductors and in the most common solution, a converter is connected to each inductor. The main aim of this paper is to suggest a way of building a multi-load/single converter system, based on the use of a series-resonant ZVS inverter supplying several resonant loads. The principle can be probably extended to different applications (DC-to-DC converters, high power induction heating applications) but their study has been restricted to a low power induction heating context. In order to make this study, suitable models for the loaded inductors had to be found. Therefore, in the first part of this document, a number of different electrical inductor models, from the basic L-R equivalent circuit to a representation taking into account eddy currents effects, are presented. The second part describes the multi-load operating principle with respecting ZVS conditions, by the analysis of an R-L inductor model. Finally, the third part completes this work with simulations, including a more realistic model of the inductors and the associated experimental validation. These emphasize the interest of this original system that is currently being evaluated for an industrial application.
200-nm-bandwidth fiber optical amplifier combining parametric and Raman gain

Theory shows that the gain bandwidth of a one-pump fiber optical parametric amplifier (OPA) using highly nonlinear fiber (HNLF) could be more than 200 nm. Under these circumstances, the OPA gain would overlap the pump-induced Raman gain. We have studied the combined effects of OPA and Raman gain theoretically and experimentally. The experimental results demonstrate a 200-nm bandwidth from a single fiber-optical amplifier and also verify that the influence of the Raman effect is relatively small, as predicted by the theory.
Systems medicine dissection of chromosome 1q amplification reveals oncogenic regulatory circuits and informs targeted therapy in cancer

Understanding the biological and clinical impact of copy number aberrations (CNA) in cancer remains an unmet challenge. Genetic amplification of chromosome 1q (chr1q-amp) is a major CNA conferring adverse prognosis in several cancers, including the blood cancer, multiple myeloma (MM). Although several chr1q genes portend high-risk MM disease, the underpinning molecular aetiology remains elusive. Here we integrate patient multi-omics datasets with genetic variables to identify 103 adverse prognosis genes in chr1q-amp MM. Amongst these, the transcription factor PBX1 is ectopically expressed by genetic amplification and epigenetic activation of its own preserved 3D regulatory domain. By binding to reprogrammed super-enhancers, PBX1 directly regulates critical oncogenic pathways, whilst in co-operation with FOXM1, activates a proliferative gene signature which predicts adverse prognosis across multiple cancers. Notably, pharmacological disruption of the PBX1-FOXM1 axis, including with a novel PBX1 inhibitor is selectively toxic against chr1q-amp cancer cells. Overall, our systems medicine approach successfully identifies CNA-driven oncogenic circuitries, links them to clinical phenotypes and proposes novel CNA-targeted therapy strategies in cancer. Significance We provide a comprehensive systems medicine strategy to unveil oncogenic circuitries and inform novel precision therapy decisions against CNA in cancer. This first clinical multi-omic analysis of chr1q-amp in MM identifies a central PBX1-FOXM1 regulatory axis driving high-risk prognosis, as a novel therapeutic target against chr1q-amp in cancer.
Prognostic Value of LHFPL Tetraspan Subfamily Member 6 (LHFPL6) in Gastric Cancer: A Study Based on Bioinformatics Analysis and Experimental Validation

Purpose The identification of biomarkers and effective therapeutic targets for gastric cancer (GC), the most common cause of cancer-related deaths around the world, is currently a major focus in research. Here, we examined the utility of LHFPL6 as a prognostic biomarker and therapeutic target for GC. Methods We explored the clinical relevance, function, and molecular role of LHFPL6 in GC using the MethSurv, cBioPortal, TIMER, Gene Expression Profiling Interactive Analysis, ONCOMINE, MEXPRESS, and EWAS Atlas databases. The GSE118919, GSE29272, and GSE13861 datasets were used for differential expression analysis. Using The Cancer Genome Atlas, we developed a Cox regression model and assessed the clinical significance of LHFPLs. In addition, we used the “CIBERSORT” algorithm to make reliable immune infiltration estimations. Western blot and immunohistochemistry were used to examine protein expression. Cell migration and invasion were assessed using transwell experiments. THP-1-derived macrophages and GC cells were co-cultured in order to model tumor–macrophage interactions in vitro. The levels of CD206 and CD163 were measured using immunofluorescence assays. The results were visualized with the “ggplot2” and “circlize” packages. Results Our results showed that in GC, LHFPL6 overexpression was significantly associated with a poor prognosis. Our findings also suggested that LHFPL6 may be involved in the activation of the epithelial–mesenchymal transition. Furthermore, LHFPL6 expression showed a positive correlation with the abundance of M2 macrophages, which are potent immunosuppressors. Conclusion LHFPL6 could be a prognostic biomarker and therapeutic target for GC.
Seam the Real with the Virtual:a Review of Augmented Reality

In this paper, we reviewed several outstanding contributions over the past decade in the field of augmented reality. The papers are selected according to their citation rate in the academic resources of Google scholar. In addition, considering that augmented reality covers several topics, and it has intersection with pervasive computing and wearable computing in concept, only the promising technologies and some prominent cases are concerned. In our opinion, a typical AR application is a solution for special application scenarios, and in most cases a comprehensive system is needed. For simplicity, we divided the technologies adopted in AR application into three categories: acquiring the data of environment, registering the virtual object in real environment and presenting the composite data. At the end of the paper, we discussed the remained problems and future development trend of augmented reality.
The short and long-term relation between human development and female unemployment: the case of Turkey

This study aimed to measure the short and long-term relation between female unemployment and the basic factors for society’s human development, namely education, health conditions and income levels, therefore it was important to test the effect of inflation in the equation which deals with unemployment. The study covered the years from 1990 to 2016, and used the United Nations Development Programme’s (UNDP) Human Development Index (HDI) to measure human development and the obtained real human development values for Turkey. To analyse the effects of real human development, information and communication technologies (ICT) and inflation on female unemployment, the Autoregressive Distributed Lag (ARDL) bounds test and the Engle–Granger test was used. As a result of the analysis, a reasonably strong, significant and negative relation was found between human development and female unemployment in the long term.
A complete three-dimensional sound intensity sensor integrated on a single chip

Complete characterization of a sound field requires measurement of both sound pressure and particle velocity. In this paper, we present a three-dimensional acoustic particle velocity sensor chip. Furthermore, a sound pressure sensor was integrated on the same chip, enabling three-dimensional sound intensity measurements. The integration of multiple sensors on a single silicon chip results in highly reproducible sensors and a very small sensor-to-sensor distance allowing for accurate single-point measurements. The latter is demonstrated by measurement of the 3D particle velocity field of a very small (1 × 1 mm2) sound source.
A.W.E. (assessing women in engineering) - designing tools for success using collaboration

Women in engineering programs around the United States are a crucial part of our country's response to the need for more women in engineering professions (Mannix, 2001). For Women in Engineering (WIE) programs to be maximally effective, they must have access to validated assessment instruments for measuring the effectiveness of their recruitment and retention activities for women in engineering studies. This paper describes the "Assessing Women in Engineering" project which is using a unique collaboration between a WlE director and an assessment specialist (AS) to develop exportable assessment instruments and models for Women In Engineering programs nationwide, thus allowing them to assess their program's activities and ultimately provide data for making well-informed evaluation decisions.
High-Efficiency and Stable Li-CO2 Battery Enabled by Carbon Nanotube/Carbon Nitride Heterostructured Photocathode.

Li-CO2 batteries are explored as promising power systems to alleviate environmental issues and to implement space applications. However, sluggish cathode kinetics of CO2 reduction/evolution result in low round-trip efficiency and poor cycling stability of the fabricated energy-storage devices. Herein, we design a heterostructued photocathode comprising carbon nanotube and carbon nitride to accelerate cathode reactions of a Li-CO2 battery under illumination. Benefiting from the unique defective structure of carbon nitride and favorable interfacial charge transfer, the photocathode effectively harvests ultraviolet-visible light to generate abundant photoexcited carriers and coordinates energetic photoelectrons/holes to participate in the discharge/charge reactions, leading to efficient photo-energy utilization in decreasing reaction barriers and enhancing thermodynamic reversibility of Li-CO2 battery. The resulting battery delivers high round-trip efficiency of 98.8% (ultralow voltage hysteresis of 0.04 V) and superior cycling stability (86.1% efficiency retention after 100 cycles).
The Influence of Social Media Marketing, Customer Engagement and Digital Advertising on Brand Trust (Go-Jek Users as Research Objects)

This study aims to see the effect of social media marketing on customer engagement and brand trust. The sample of this research is people who use go-jek and have used go-jek with a total of 55 respondents. The validity test uses the loading factor value and the reliability test uses the Cronbach`c alpha value and the composite reliability is based on the PLS application. In addition, from third parties submitted by all parties. The weakness of this research is the relatively small number of respondents.
Where Does Carsharing Work?

A tool to assess the market potential for new carsharing operations in urban communities is examined and applied. The research is based on the analysis conducted for TCRP Report 108: Carsharing: Where and How It Succeeds. Geographic market segments in urban areas are analyzed. A geographic information system (GIS)–based analysis of 13 U.S. regions finds that neighborhood and transportation characteristics are more important indicators for carsharing success than the individual demographics of carsharing members. Results indicate that low vehicle ownership has the strongest, most consistent correlation to the amount of carsharing service in a neighborhood. Thresholds based on analysis results are outlined for low service (i.e., carsharing may be viable but limited growth can be expected) and high service (i.e., carsharing is likely to flourish). This tool to identify neighborhoods that can support carsharing is applied to a community seeking to establish a carsharing program: Austin, Texas. The analysis finds that several Austin neighborhoods have the characteristics to support carsharing (e.g., low vehicle ownership rates and high percentages of one-person households), but few Austin neighborhoods could support a high level of carsharing service.
ECG-Based Identification of Sudden Cardiac Death through Sparse Representations

Sudden Cardiac Death (SCD) is an unexpected sudden death due to a loss of heart function and represents more than 50% of the deaths from cardiovascular diseases. Since cardiovascular problems change the features in the electrical signal of the heart, if significant changes are found with respect to a reference signal (healthy), then it is possible to indicate in advance a possible SCD occurrence. This work proposes SCD identification using Electrocardiogram (ECG) signals and a sparse representation technique. Moreover, the use of fixed feature ranking is avoided by considering a dictionary as a flexible set of features where each sparse representation could be seen as a dynamic feature extraction process. In this way, the involved features may differ within the dictionary’s margin of similarity, which is better-suited to the large number of variations that an ECG signal contains. The experiments were carried out using the ECG signals from the MIT/BIH-SCDH and the MIT/BIH-NSR databases. The results show that it is possible to achieve a detection 30 min before the SCD event occurs, reaching an an accuracy of 95.3% under the common scheme, and 80.5% under the proposed multi-class scheme, thus being suitable for detecting a SCD episode in advance.
Influence of the cellulose and sulfate ratio on voltage generation in Winogradsky columns

The Winogradsky column is a nutrient-enriched sediment column for studying microbial diversity and the sulfur cycle. In this device, microorganisms generate a vertical chemical gradient, and voltage production can be measured with a graphite plate (buried in sediment) and a graphite plate (submerged in water). This system is similar to sediment microbial fuel cells (SMFC) used for generating lectrical energy. V ltage generation in SMFCs has been established with different cellulose concentrations. However, cellulose and sulfate proportions have not been tested so far. Cellulose/sulfate ratios can change the microbial community, vertical chemical gradient, and potential difference. Therefore, this work aims to test the effect of different cellulose/sulfate ratios in Winogradsky columns to improve voltage generation. Voltage was generated in cellulose/sulfate ratios between 0.08 and 1.28. An optimal cellulose/sulfate ratio of 0.75, identified with the response surface model, produced a voltage between 300 to 400 mV for 20 days. These dev ces represent an altern tive for renewable energy gener tion where cellulose waste could be used as a carbon source.
Does Pancreatic Fistula Affect Long-Term Survival after Resection for Pancreatic Cancer? A Systematic Review and Meta-Analysis

Simple Summary The real influence of postoperative pancreatic fistula (POPF) on long-term survival after pancreatic cancer resection is unclear. The purpose of the present study was therefore to conduct a systematic review and meta-analysis of the impact of POPF on the disease-free and overall survival of patients with pancreatic cancer. Our results highlighted that clinically relevant POPF after surgery for PDAC seems to be significantly associated with shorter DFS and OS. Confirmation, with future studies, of a negative impact of POPF on survival may encourage the widespread use of risk-stratification tools for assessing fistula, centralization of patients, and probably a closer oncological follow-up. Abstract Background: The impact of postoperative pancreatic fistula (POPF) on survival after resection for pancreatic ductal adenocarcinoma (PDAC) remains unclear. Methods: The MEDLINE, Scopus, Embase, Web of Science, and Cochrane Library databases were searched for studies reporting on survival in patients with and without POPF. A meta-analysis was performed to investigate the impact of POPF on disease-free survival (DFS) and overall survival (OS). Results: Sixteen retrospective cohort studies concerning a total of 5019 patients with an overall clinically relevant POPF (CR-POPF) rate of 12.63% (n = 634 patients) were considered. Five of eleven studies including DFS data reported higher recurrence rates in patients with POPF, and one study showed a higher recurrence rate in the peritoneal cavity. Six of sixteen studies reported worse OS rates in patients with POPF. Sufficient data for a meta-analysis were available in 11 studies for DFS, and in 16 studies for OS. The meta-analysis identified a shorter DFS in patients with CR-POPF (HR 1.59, p = 0.0025), and a worse OS in patients with POPF, CR-POPF (HR 1.15, p = 0.0043), grade-C POPF (HR 2.21, p = 0.0007), or CR-POPF after neoadjuvant therapy. Conclusions: CR-POPF after resection for PDAC is significantly associated with worse overall and disease-free survival.
A PROBLEM IN RF SWITCHES OF MULTIPLEXING BPM SYSTEM

At SPring-8, we have been developing a new detection circuit for beam position measurement with a resolution of submicron and a measuring interval of a few milliseconds with high stability. In the circuit, a multiplexing method using RF switches is employed in order for a drift of the circuit to be canceled. To achieve design performance, the switches must have following properties: a short switching time, high repeatability and long lifetime. During the evaluation of components for the new detection circuit, we found that some RF switches made of GaAs had a problem that the output signal changed for a few mdB for seconds after the switches were turned on. A few mdB, which is 1/10000 in voltage ratio, corresponds to a beam position error of a few microns in SPring-8. Such position error is out of the required specifications. We investigated several kinds of RF switches and decided to adopt a CMOS RF switches as the multiplexer. In this paper, we report switching properties of several RF switches and demonstration of beam position measurement using the switches.
Performance of digital magnetic recording with equalization and offtrack interference

The relative performance of well-equalized peak detection, partial response, and decision feedback detection in an intertrack-interference (ITI)-dominated noise environment is calculated, showing that it depends heavily on the intertrack interference. It is found that equalized peak detection performs relatively well at low linear density and extreme offtrack positions (e.g. 20%) and that partial response with Viterbi detector performs the best at small offtrack positions. However, overall, the decision feedback equalizer provides the best performance for a given amount of complexity, and its advantages are discussed. Tolerance to offtrack error as a function of linear density and, taking offtrack performance into account, tradeoffs between increasing linear or areal density are addressed. >
Gender Stereotyping and Inequality Behind the Slogans: A Case Study in Chinese Tertiary Education

The increasing number of female students in China has contributed to reducing the gender gaps in tertiary education over the past decades; however, the debate about gender inequality in tertiary education is ongoing. This study examines how the slogans on the banners for Girls’ Day celebrations from 2018–2020 on university campuses in mainland China convey male students’ willingness to provide help and support for the perceived academic issues faced by female college students, while surreptitiously conveying gender stereotyping and intelligence quotient (IQ) prejudice in the current university campus culture. These slogans occupy a prominent position on campus and help to evaluate the perceptions of both male and female college students regarding these issues. Data were gathered from semi-structured interviews with 16 undergraduate students at two universities. The analysis revealed that female IQ bias based on gender stereotyping is an enduring issue, which has been unintentionally inherited from previous generations of Chinese college students. The article reveals that despite the increased number of female college students, “benevolent discrimination” against women still exists in various forms in the campus culture and gender roles have not transformed much. The findings of this study can inform future gender education, orienting its effort towards a clearly identified niche of users.
A model for vein formation in higher plants

Experiments on vein regeneration (Jost 1942; Jacobs 1952) suggest that a signal of some kind, which can cause the differentiation of veins, flows from a source in the growing tissues of leaves towards the root. Sachs (1969, 1978) has given evidence that the capacity of a given pathway to transport this signal increases with the flux it carries. He suggests that this progress could cause the canalization of signal flow into a pattern of discrete strands, which subsequently differentiate into veins. I formulate here a mathematical model based on these assumptions, and show that it can generate well defined strands. Given plausible estimates for diffusion constants and polar transport rates, it appears that vein formation could occur by this mechanism over an appropriate distance within an acceptably short time. I show that this model can simulate Sachs’s experiments on vein formation. I also show that, with suitable assumptions about the distribution of source activity, the model can generate elaborate networks, with branches and loops of the kind seen in the leaves of higher plants.
Theoretical Disquisition on the Static and Dynamic Characteristics of an Adaptive Stepped Hydrostatic Thrust Bearing with a Displacement Compensator

Stepped hydrostatic thrust bearings used in metal-cutting machines are characterized by high load capacity and damping, which ensure the stable operation of structures. However, in comparison with throttle thrust bearings, they have a high compliance. It is preferable that, in addition to the main bearing function, a modern hydrostatic bearing has the ability to provide low (including negative) compliance for the implementation of an adaptive function in order to actively compensate for the deformation of the machine resilient system, thereby increasing the accuracy of metalworking. This paper considers the design of a stepped hydrostatic thrust bearing, which, in order to reduce the compliance to negative values, features a technical improvement consisting of the use of an active displacement compensator on an elastic suspension. In this paper, the results of mathematical modeling and theoretical research of stationary and non-stationary modes of operation of the adaptive thrust bearing are presented. The possibility of a significant reduction in the static compliance of the structure, including the negative compliance values, is shown. It was found that negative compliance is provided in a wide range of loads, which can be up to 80% of the range of permissible bearing loads. The study of the dynamic characteristics showed that with a targeted selection of parameters that ensure optimal performance, the adaptive thrust bearing is able to operate stably in the entire range of permissible loads. It has been established that an adaptive stepped hydrostatic thrust bearing with a displacement compensator has a high stability margin, sufficient to ensure its operability when implementing the adaptive function.