Miracle-dz/UniFAR-FTUs huggingface dataset:
Lightweight Signal Processing Algorithms for Human Activity Monitoring using Dual PIR-sensor Nodes

A dual Pyroelectric InfraRed (PIR) sensor node is used for human activity monitoring by using simple data processing techniques. We first point out the limitations of existing approaches, employing PIR sensors, for activity monitoring. We study the spectral characteristics of the sensor data for the cases of varying distance between the sensor and moving object as well as the speed of the object under observation. The sampled data from two PIR sensors, is first processed individually to determine the activity window size, which is then fed to a simple algorithm to determine direction of motion.We also claim that human count can be obtained for special scenarios. Preliminary results of our experimentation show the effectiveness of the simple algorithm proposed and give us an avenue for estimating more involved parameters used for speed and localization.
Microwave Photoinduced Varactor on Silicon Substrate

In this paper, we show that when a metallic microstrip line deposited on silicon is illuminated at its end while its entry is being connected to an ultra high frequency generator, a photoinduced load is obtained at its extremity. It is proven by experimental and simulation results that this load behaves as a « photoinduced varactor ». An equivalent circuit composed of a resistance and a capacitance in parallel is found to fit the component behaviour accurately. The dependence of these discrete elements on the DC applied voltage, the frequency and the illumination optical power is highlighted. A strong non-linear variation with the DC applied voltage is pointed out.
Choice of Target Audience for IS Research: Reflections on Discussions with IS Academic Leaders in the UK

The IS field prides itself on its closeness to practice and needs to ensure its relevance under growing pressures from governments and business for improved utilisation of research results. In this paper we consider choice-making in the research activity from the perspective of Resource-Dependence Theory, with a particular focus on the choice of target audience for research results. IS academic leaders in UK universities were interviewed to gain insights into the influences affecting their choices, taking a broad view of the research context and process, the researchers themselves, and the stakeholders of IS research. The paper aims to provide insights for IS researchers as they reflect on their own individual practice of research and to encourage the explicit inclusion of Resource-Dependence Theory into stakeholder analysis within IS theory. For practitioners it should provide some illumination on the world of academia.
Strategic use of an adenoviral vector for rapid and efficient ex vivo‐generation of cytomegalovirus pp65‐reactive cytolytic and helper T cells

Cytomegalovirus (CMV) reactivation can cause severe complications for transplant patients. Such patients can be protected against CMV‐associated diseases through reconstitution of donor‐derived CMV‐reactive cytolytic and helper T cells. We have developed a strategic protocol for efficient simultaneous generation of CMV‐reactive CD8+ and CD4+ T cells ex vivo. The protocol uses peripheral blood lymphocytes (PBLs), antigen‐modified mature dendritic cells (DCs) generated in only 3 d and an adenoviral vector encoding the CMV pp65 antigen (Adpp65) both as an endogenous and exogenous source of antigen. PBLs stimulated once with Adpp65‐transduced DCs (endogenously expressed pp65) resulted in preferential activation and expansion of pp65‐specific CD8+ T cells while PBLs stimulated with DCs pulsed with cell lysate from Adpp65‐transduced autologous monocytes (exogenously expressed pp65) yielded pp65‐specific CD4+ T cells. Stimulation with double‐modified DCs efficiently activated and expanded cytolytic and helper T cells simultaneously. The frequency of T cells producing interferon‐γ in response to pp65 increased after one stimulation on average 9·6‐fold to 4·3% for CD8+ T cells and 25·8‐fold to 6·5% for CD4+ T cells. This implies that sufficient number of pp65‐specific cytolytic and helper T cells for adoptive transfer may be obtained in only 2 weeks.
Object resolved teleoperation

A control concept referred to as object-resolved teleoperation is introduced in this paper in which motion or force is imparted to a remote object in order to achieve a desired action by the object. The object might be a hand-held tool or an airplane and the desired interaction might be control of its spatial position or interaction with the environment. The human interface to the master is a hand-held proxy for the object. At the remote site, the object motion or force commands are resolved into the appropriate commands for the actuation system. The potential advantages of ORT are: improvement in human-machine interaction, the consequence of the operator's cognitive task and command response being identical to those he would perform if he were manipulating the object; and the opportunity to share control between the operator and an intelligent controller at the remote site in such ways as to make best use of the capabilities of each. In this paper, application to grasp and manipulation is discussed.
Intra‐episode hypomanic symptoms during major depression and their correlates

Abstract Recent studies have shown that 40–50% of major depressive disorders (MDD) may become bipolar with time. Intra‐episode hypomanic symptoms in MDD may be a first step in this shift. The purpose of the present study was to find factors associated with intra‐episode hypomanic symptoms in MDD. Two hundred and forty‐three consecutive MDD outpatients were interviewed with the Structured Clinical Interview for Diagnostic and Statistical Manual of Mental Disorders (4th edn; DSM‐IV), Clinician Version (SCID‐CV), as modified by Benazzi and Akiskal (J. Affect. Disord. 2003; 73: 33–38). History of hypomania and presence of hypomanic symptoms during major depressive episode (MDE) were systematically assessed. Intra‐episode hypomanic symptoms were defined as an MDE combined with three or more hypomanic symptoms, following Akiskal and Benazzi (J. Affect. Disord. 2003; 73: 113–122). Major depressive disorder with intra‐episode hypomanic symptoms (MDD + H) was compared to MDD without hypomanic symptoms on classic bipolar validators. It was found that MDD + H (usually irritability, distractibility, racing thoughts, psychomotor agitation, and more talkativeness) was present in 32.5% of patients. Patients with MDD + H versus MDD had significantly lower age at onset, more atypical depressions, and more bipolar family history. Recurrences were not significantly different. Multivariate logistic regression found that bipolar family history and atypical depression were significantly and independently associated with MDD + H. Findings suggest that MDD + H may be associated with a bipolar vulnerability. Duration of illness and recurrences do not seem to be important for the onset of MDD + H. Bipolar genetic vulnerability seems to be required for onset of intra‐episode hypomanic symptoms in MDD. Intra‐episode hypomanic symptoms might be the first step of a process leading to the switch of MDD to bipolar disorders. Predicting the switch might have important treatment implications, because antidepressants used alone may worsen the course of bipolar disorders. Prospective studies are required to support these findings and hypotheses.
Decreased Binding of Peptides-MHC Class I (pMHC) Multimeric Complexes to CD8 Affects Their Binding Avidity for the TCR But Does Not Significantly Impact on pMHC/TCR Dissociation Rate1

The CD8 coreceptor plays a crucial role in both T cell development in the thymus and in the activation of mature T cells in response to Ag-specific stimulation. In this study we used soluble peptides-MHC class I (pMHC) multimeric complexes bearing mutations in the CD8 binding site that impair their binding to the MHC, together with altered peptide ligands, to assess the impact of CD8 on pMHC binding to the TCR. Our data support a model in which CD8 promotes the binding of TCR to pMHC. However, once the pMHC/TCR complex is formed, the TCR dominates the pMHC/TCR dissociation rates. As a consequence of these molecular interactions, under physiologic conditions CD8 plays a key role in complex formation, resulting in the enhancement of CD8 T cell functions whose specificity, however, is determined by the TCR.
Validation of SWAT Model for Prediction of Water Yield and Water Balance: Case Study of Upstream Catchment of Jebba Dam in Nigeria

— Estimation of water yield and water balance in a river catchment is critical to the sustainable management of water resources at watershed level in any country. Therefore, in the present study, Soil and Water Assessment Tool (SWAT) interfaced with Geographical Information System (GIS) was applied as a tool to predict water balance and water yield of a catchment area in Nigeria. The catchment area, which was 12,992km 2 , is located upstream Jebba hydropower dam in North central part of Nigeria. In this study, data on the observed flow were collected and compared with simulated flow using SWAT. The correlation between the two data sets was evaluated using statistical measures, such as, Nasch-Sucliffe Efficiency (NSE) and coefficient of determination (R 2 ). The model output shows a good agreement between the observed flow and simulated flow as indicated by NSE and R 2 , which were greater than 0.7 for both calibration and validation period. A total of 42,733 mm of water was predicted by the calibrated model as the water yield potential of the basin for a simulation period between 1985 to 2010. This interesting performance obtained with SWAT model suggests that SWAT model could be a promising tool to predict water balance and water yield in sustainable management of water resources. In addition, SWAT could be applied to other water resources in other basins in Nigeria as a decision support tool for sustainable water management in Nigeria.
Efficacy of clotinab in acute myocardial infarction trial-ST elevation myocardial infarction (ECLAT-STEMI).

BACKGROUND This study investigated the efficacy and the safety of the upstream glycoprotein (Gp) IIb/IIIa inhibitor (clotinab; ISU ABXIS, Seoul, Republic of Korea) under 600-mg clopidogrel pretreatment compared with provisional use in ST-elevation myocardial infarction (STEMI). METHODS AND RESULTS A total of 786 STEMI patients were randomized to upstream use in the emergency room (ER) (n = 392) or provisional use during percutaneous coronary intervention (PCI) (n = 394). All patients were prescribed 600-mg clopidogrel in the ER. The primary endpoint was the 30-day incidence of composite events including death, nonfatal myocardial infarction, target vessel revascularization, and stroke. There was no significant difference in the events that occurred in 40 patients (10.2%) in the upstream arm and 55 patients (14.0%) in the provisional arm during the 30 days (odds ratio 0.70, 95% confidence interval 0.45-1.08). Major bleeding was higher in the upstream arm (1.5% vs. 0%, P = 0.02). However, there was a significant reduction in 30-day composite events in the upstream arm in the high-risk population (Killip class ≥II or GRACE score >140). CONCLUSIONS The upstream use of clotinab under a 600-mg clopidogrel loading may not significantly reduce cardiac events following primary PCI but may improve the clinical outcome in high-risk patients.
Packet loss protection for interactive audio object rendering: A multiple description approach

This paper presents a new framework for compression and transmission of simultaneously occurring audio objects through packet loss channels in order to maintain user Quality of Experience (QoE). The audio objects are compressed into two mono mixtures, by exploiting sparsity of multichannel audio signals to identify the two most dominant time-frequency components in terms of an energy measure. These mixtures are further compressed using the MP3 audio codec, with the optimised transmission model selected from several channel coding models based on the Forward Error Correction (FEC) and Multiple Description Coding (MDC) packet loss protection techniques. Audio objects can be recovered robustly from any received description(s) allowing real-time selective reproduction at the listeners' end. Results from spectral distortion measurements indicate the proposed scheme maintains the perceptual quality of the audio objects across a wide variety of packet loss conditions.
Rheumatic fever presentation and outcome: a case-series report.

OBJECTIVE To assess the clinical characteristics and outcome of a rheumatic fever case-series from a referral hospital over the last 20 years. PATIENTS AND METHODS Patients under the age of 18 years, diagnosed with rheumatic fever between 1986 and 2007 were retrospectively assessed to estimate the carditis and relapse rates, by use of descriptive and survival analysis. RESULTS Of 178 cases identified, 134 were included. During the acute phase, 66.4% had polyarthritis, 56.8% had carditis, 28.6% had chorea, 1.5% had subcutaneous nodules, and 1.5% had erythema marginatum. The association of carditis and arthritis occurred in 40%. Carditis and chorea were more frequent among female gender. High antistreptolysin-O titres were found in 58.3%, and family history of rheumatic fever, in 14.5%. Mean follow-up was 6.8 years (1.1 to 16.9). Relapse was observed in 15%, hospital admissions in 27.6%, and follow-up discontinuation in 47.4% after a mean of 5.1 years. Carditis and relapse probabilities were 17.5% and 13.2%, respectively, five years after the initial attack. CONCLUSION The risk of carditis and relapse of rheumatic fever was higher within the first five years. Follow-up discontinuation was frequent, pointing to the need of measures to improve adherence to prophylaxis and follow-up.
Design and analysis of a novel omnidirectional stereovision system

Omnidirectional stereovision has wide applications in object detection, three-dimensional reconstruction and robot navigation thanks to its large field-of-view. In this paper, a novel configuration that consists of one single camera and multiple mirrors is proposed. The significant improvement is to design a principal mirror above the four sub mirrors placed in a plane to achieve four pairs of stereovision. A projection model with configuration parameters of this system is investigated in order to analyze the precision in reconstruction. Furthermore, the error propagation from image points to the triangulated 3D points and the effects of the system parameters on resulting measurement error are also given. Based on the simulation results, the optimal interval of these parameters is obtained.
How effective is cockpit resource management training? Exploring issues in evaluating the impact of programs to enhance crew coordination.

The question "Is cockpit resource management effective? " has been asked frequently in the years since 1979 when a National Aeronautics and Space Administration (NASA)/Industry workshop addressed the concepts of crew coordination and effective utilization of all available resources in flight operations (Cooper, White, & Lauber, 1980). If one looks at the proliferation of cockpit resource management (CRM) training programs in domestic and foreign, civil and military aviation, and the enormous investment in time and money that they entail, it would appear that the question has been answered in the affirmative. It is our position, however, that the question remains open and that empirical evidence is just beginning to accumulate.
Mouse ZAR1‐like (XM_359149) colocalizes with mRNA processing components and its dominant‐negative mutant caused two‐cell‐stage embryonic arrest

Maternal effect genes and encoding proteins are necessary for nuclear reprogramming and zygotic genome activation. However, the mechanisms that mediate these functions are largely unknown. Here we identified XM_359149, a Zar1‐like gene that is predominantly expressed in oocytes and zygotes, which we designated Zar1‐like (Zar1l). ZAR1L‐EGFP formed multiple cytoplasmic foci in late two‐cell‐stage embryos. Expression of the ZAR1L C‐terminus induced two‐cell‐stage embryonic arrest, accompanied with abnormal methylation of histone H3K4me2/3 and H3K9me2/3, and marked down‐regulation of a group of chromatin modification factors including Dppa2, Dppa4, and Piwil2. When ectopically expressed in somatic cells, ZAR1L colocalized with P‐body components including EIF2C1(AGO1), EIF2C2(AGO2), DDX6 and LSM14A, and germline‐specific chromatoid body components including PIWIL1, PIWIL2, and LIN28. ZAR1L colocalized with ZAR1 and interacted with human LIN28. Our data suggest that ZAR1L and ZAR1 may comprise a novel family of processing‐body/chromatoid‐body components that potentially function as RNA regulators in early embryos. Developmental Dynamics 239:407–424, 2010. © 2009 Wiley‐Liss, Inc.
Interplay between the kinin B1 receptor and inducible nitric oxide synthase in insulin resistance

Kinins are vasoactive and pro‐inflammatory peptides whose biological effects are mediated by two GPCRs, named B1 and B2 receptors. While the B2 receptor plays a protective role in the cardiovascular system via the activation of endothelial NOS, the B1 receptor is associated with vascular inflammation, insulin resistance and diabetic complications. Because the B1 receptor is a potent activator of the inducible form of NOS (iNOS), this study has addressed the role of iNOS in the deleterious effects of B1 receptors in insulin resistance.
Improved alkaloid content in callus culture of Catharanthus roseus

The low yield and high market price of the pharmaceutically important alkaloids of Catharanthus roseus (L.) G. Don viz. vincristine, vinblastine and ajmalicine have created interest in improved alternative routes for their production such as using cell and tissue culture. The callus developed on Murashige and Skoog (MS) media supplemented with different concentrations of auxins and cytokinins was found to have variable alkaloid contents. Combinations of auxins with cytokinins were found to be better for leaf callus growth and enhancement of alkaloid content. The highest enhancement of total alkaloid content was found in 0.50 mg/l of 2, 4-D and 1.0 mg/l of BA, compared with other combinations. Our findings indicated that in addition to plant growth regulators and strength of the MS media, various carbon sources and their concentrations had a significant influence on leaf callus growth and total alkaloid content. It was found that half strength MS basal medium supplemented with 2, 4-D and BA (0.5mg/l and 1.0 mg/l, respectively) and 6% sucrose was best for biomass production of leaf callus and enhancement of alkaloid accumulation in C. roseus.
'Pseudocystic' appearance of non-Hodgkin's lymphomatous nodes: an infrequent finding with high-resolution transducers.

AIMS A pseudo-cystic appearance and posterior enhancement are previously reported to be diagnostic sonographic features of lymph node involvement in non-Hodgkin's lymphoma. This study was undertaken to determine whether these ultrasonic features remain with the use of high-resolution transducers. MATERIAL AND METHODS A review of ultrasound examinations in 32 patients with proven lymphomatous cervical lymphadenopathy (27 non-Hodgkin's lymphoma, five Hodgkin's disease) was performed. A total of 95 lymph nodes were assessed for size, shape, posterior enhancement and internal architecture. All examinations were performed with the same high-resolution transducer and by the same sonologist. RESULTS Lymphomatous nodes (irrespective of type) are frequently heterogeneous (68-86%), have a micronodular pattern (63-69%) and less commonly demonstrate posterior enhancement (9-26%). CONCLUSION Using a high-resolution ultrasonic transducer, cervical nodes involved with lymphoma (irrespective of type) commonly demonstrate a heterogeneous micronodular pattern. The pseudocystic appearance of nodes with posterior enhancement in non-Hodgkin's nodes is seen infrequently.
Psychiatric Morbidity and Quality of Life in Vitiligo Patients

Background: Vitiligo has underlying mental illness but mostly not diagnosed and never used psychiatric medication. Hence, the problem persists affecting mostly the individual's quality of life. Aim: Assessing the quality of life, level of depression, and self-esteem of patients with vitiligo and give psychiatric medication for underlying mental illness. Materials and Methods: The study conducted at Owaisi Hospital Research Centre, Hyderabad. The patients registered for dermatologist consultation were also registered for consultation with psychiatrist to rule out any mental illness after detailed evaluation using standardized scales. Results: Patients suffering with vitiligo had depression and low self-esteem; their quality of life was disturbed. Conclusion: The findings provide the role of Mental Health Professionals involved in the field of dermatology for the patients suffering with vitiligo.
Risks to Effective Knowledge Sharing in Agile Software Teams: A Model for Assessing and Mitigating Risks

We present an empirically grounded and theoretically informed model for the assessment and mitigation of risks to effective knowledge sharing in agile development. The model is anchored in empirical insights from four agile projects across two software companies and in extant research on risk‐strategy analysis and knowledge sharing in software development. We develop the model as part of the long‐standing tradition of presenting risk management models dedicated to specific issues in software development and confirm its practical usefulness in one of the software companies studied. The model offers concepts and processes to assess a project's knowledge sharing risk profile and articulate an overall resolution strategy plan to mitigate the risks. The results highlight how different knowledge sharing risk management profiles can lead to different project performance outcomes. We conclude with a discussion of research opportunities that the results offer software development scholarship. © 2016 John Wiley & Sons Ltd
Design of an equal division single-band filtering power divider based on ring resonator band-pass filter

In this paper a ring resonator (RR) based band pass filter (BPF) is integrated in the power divider for simultaneous filtering and equal division functions. The proposed co-axial feeding mechanism for the RR ensures the BPF response. Exploiting band-pass characteristics and matching the filter to 70.7 Ω, the RR BPF is integrated in place of the conventional quarter wave transformer in the power divider. In order to ensure good output isolation and return loss (RL), a 50Ω extended transmission line and a resistor is used. Experimental validation was carried out by fabricating the proposed filtering divider. The simulated and measured S-parameter responses were found in good agreement at the fundamental design frequency of 3 GHz and fractional bandwidth of 15%.