Miracle-dz/UniFAR-FTUs huggingface dataset:
Designing health-literate health care organization: A literature review

Health literacy is usually described as a silent epidemic, which is challenging the sustainability of health care systems all over the world. The scientific literature has discussed the drawbacks of marginal health literacy on the functioning of the health care organizations. In particular, limited health literacy has been associated with: poorer ability of patients to comprehend health information, deficient medication adherence, insufficient use of prevention services, higher hospitalization rates, and greater health service utilization. In most of the cases, health literacy has been understood as an individual trait, which ultimately concerns the patients’ ability to obtain, process, and understand health information to navigate the health system. Alternatively, poor attention has been paid to the health literacy of the organizations operating within the health system, that is to say “organizational health literacy”. Indeed, neither the scholars nor the practitioners have adequately addressed the role played by the health care organizations to meet the needs of patients who live with limited health literacy. To contribute in filling such a gap, this study discusses the design and the structure of health-literate health care organizations. For this purpose, a systematic literature review was performed, involving 69 articles indexed in Scopus-Elsevier, Pub-Med, and Google Scholar to point out how the health care organizations face health literacy issues and to discuss what tools are used by the health care organizations to meet the information needs of people living with limited health literacy. Health-literate health care organizations turn out to be crucial to enhance patient engagement and improve health outcomes.
Faculty Opinions recommendation of Mammalian kinetochores count attached microtubules in a sensitive and switch-like manner.

The spindle assembly checkpoint (SAC) prevents anaphase until all kinetochores attach to the spindle. Each mammalian kinetochore binds many microtubules, but how many attached microtubules are required to turn off the checkpoint, and how the kinetochore monitors microtubule numbers, are not known and are central to understanding SAC mechanisms and function. To address these questions, here we systematically tune and fix the fraction of Hec1 molecules capable of microtubule binding. We show that Hec1 molecules independently bind microtubules within single kinetochores, but that the kinetochore does not independently process attachment information from different molecules. Few attached microtubules (20% occupancy) can trigger complete Mad1 loss, and Mad1 loss is slower in this case. Finally, we show using laser ablation that individual kinetochores detect changes in microtubule binding, not in spindle forces that accompany attachment. Thus, the mammalian kinetochore responds specifically to the binding of each microtubule and counts microtubules as a single unit in a sensitive and switch-like manner. This may allow kinetochores to rapidly react to early attachments and maintain a robust SAC response despite dynamic microtubule numbers.
A reply

in June 2011 [2]. Within our institution we have an established a fascia iliaca block (FIB) service provided by Trauma and Orthopaedic Nurse Practitioners for patients with a fractured neck of femur. We find this nerve block very useful for pain control, and patients subsequently require minimal systemic analgesia. During a recent audit the only complication noted, other than block failure, was excessive sedation following administration of an effective FIB. Without exception, these cases had received their FIB after significant amounts of morphine had been given for pain control. Approximately 1 h after FIB, naloxone was required to reverse the excessive opioid sedation. We are concerned that the NICE guidelines advocate a delayed approach to FIB placement whereas the AAGBI guidelines suggest a ‘single shot ⁄ continuous nerve block may be successfully administered’ [1, 2]. If the NICE guidelines are rigorously applied then the FIB should be used after paracetamol and opioid administration if pain is still an issue. This approach increases the risk of complications associated with FIB and delayed opioid sedation. We strongly believe that the correct timing for the FIB is immediately after radiographic confirmation of the diagnosis, or earlier in cases of high clinical suspicion, and FIB should be offered to all in whom it is not contraindicated. This maximises pain relief in the most painful early period and negates the need for strong systemic analgesia in this physiologically frail group. At our hospital we are trying to improve early access to FIB in order to avoid the complications described above, and are developing a training program to enable emergency staff to perform FIBs at their initial assessment. This has been shown to be achievable and provides safe and effective analgesia in the emergency department [3]. We agree with the accompanying editorial calling for a more prominent role for nerve blocks in the pain management of this patient population [4]. We also suggest that the delayed use of FIBs on the analgesic ladder is incorrect, and will potentially create a serious complication that will tarnish the reputation of a very useful block.
Calculating the water salt production function parameters of seed maize under water salt combination stress

In order to explore the relationship between crop yield and water salt stress, field experiments were conducted under deficit irrigation with saline water in Shiyang Rive Basin. It introduced into the crop-water-salt production function. The crop-water-salt production function parameters were calibrated and validated based on the field experiments measured data. The results showed that the simulated evapotranspiration and yield agreed well with the measured values of seed maize at different growth stages. The crop-water-salt production function parameters after calibration and validation were b=6.72, ky1=0.43, ky2=0.82, ky3=1.41, ky4=0.65, ky5=0.24, respectively. The yield response factor (ky) reflected sensitivity to the seed maize at different growth stages under water salt combination stress. The crop-water-salt production function can well simulate the seed maize evapotranspiration and yield under water salt combination stress after calibration and validation.
Evolving techniques for the detection of Listeria monocytogenes: underlining the electrochemical approach

ABSTRACT Foodborne illness is posing major health problems among all world population. Among all pathogens, bacteria are causing more severe infections in food samples. Listeria monocytogenes is most lethal foodborne illness in human, causing approximately 1600 people infected and 260 deaths each year in the USA. In this review, numerous strategies of detection are presented together with discussions about their pros and cons. The primary emphasis has been done on electrochemical detection methods for L.monocytogenes. More than hundred research papers have been critically studied to elucidate the impact of L.monocytogenes on mortality and global socio-economic development. The literature study proves that electrochemical approach is the best among all traditional methods and using aptamers as biological recognition elements offer more advanced features to the diagnosis. Studies concluded that apta-sensors increase the sensitivity and specificity of L.monocytogenes detection.
Exploring consumers’ knowledge and perceptions of unconventional food plants: case study of addition of Pereskia aculeata Miller to ice cream

marinadaltoe@utfpr.edu. br Abstract Unconventional food plants (UFPs) are by definition little known and infrequently consumed by population, although are recognized as having high nutritional value and economic potential. The objective was to assess the knowledge about UFPs by the population in the southwestern region of the state of Paraná, Brazil; and more particularly to evaluate the holistic perception of an ice cream prepared with the UFP ora-pro-nóbis , a plant that is gaining attention in recent years We applied a questionnaire to assess knowledge of several UFPs; check-all-that-apply questions to evaluate the knowledge, habits and perceptions regarding UFPs; and word association (WA) and acceptance tests for holistic and hedonic evaluation of the ice cream. The results revealed that the best known UFP species were taro and roselle, followed by ora-pro-nóbis and lamb’s ear. They also revealed that among participants, the majority (63%) had heard of UFPs, but only 19.4% stated they had the custom of eating these plants. The respondents also indicated interest in buying UFPs, but stated it was not easy to find them for sale. On the WA test, ice cream was described mainly in the categories tasty, innovation, sweet taste, plant flavor, smooth and creamy, and the acceptance index was guided by public knowledge of acceptance
Effect of supplementation of Kappaphycus alvarezii based seaweed product on rumen fermentation
 parameters under in vitro conditions

© Abstract: In vitro trials were conducted to study the effect of fortification of different levels of K. alvarezii based seaweed product ( K. Alvarezii powder: Gracilaria salicornia powder : K. alvarezii sap powder in 1: 1: 1 ratio) to basal substrate on digestibility and rumen fermentation parameters. The results showed that supplementation of different levels (0, 0.5, 1.0, 1.5, 2.0, 2.5 and 3.0%) of K. alvarezii based seaweed product to the basal substrate consisting of sugargraze fodder (sorghum × sorgho × sudan grass hybrid) and concentrate mixture in 60: 40 ratio) did not affect in vitro true DM and OM digestibility, total gas production, methane production, ammonia-N, microbial biomass production, individual volatile fatty acid production and metabolisable energy values to any significant
The inﬂuence of MCPA on soil ecotoxicity and the presence of genes involved in its biodegradation

: The aim of this study was to evaluate the changes in ecotoxicity of agricultural soil under the in ﬂ uence of Agritox 500SL, an herbicide from the phenoxyacid group, containing MCPA (2-methyl-4-chlorophenoxyacetic acid), applied every 3 weeks for 3 months. Biodegradation potential in control and weathered soil was con ﬁ rmed by the analysis of the functional gene tfdA using PCR technique. Properties of the soil were assessed by the analysis of granulometric composition, pH, the content of macroelements and heavy metals. The soil ecotoxicity was measured using biotests Phytotoxkit ® and Microtox ® . The content of Ni (70 mg/kg) and Cr (21 mg/kg) was especially high in the soil with Agritox 500SL. The highest toxic effect for test organisms was observed in freshly spiked soil: 99% L. sativum , 97% S. alba , 66% S. saccharatum (% root growth inhibition) and 76% V. ﬁ scheri (% luminescence inhibition). Weathering processes signi ﬁ cantly decreased the soil ecotoxicity being 36%, 34% and 3% for V. ﬁ scherii , S. alba and L. sativum , respectively. S. saccharatum showed 12% stimulation of the root length. Molecular analysis con ﬁ rmed the potential of indigenous soil bacteria to biodegrade MCPA by the presence of tfdA α and tfdA Class III genes in the studied soil. The obtained results proved that either MCPA and residues of its decomposition or additional supporting substances in Agritox 500 SL, can in ﬂ uence enhanced soil ecototoxicity. The presence of functional tfdA genes in both: control and weathered soil, con ﬁ rmed the high potential of indigenous soil bacteria to degrade MCPA.
The Effect Size Statistic—Applications for the Strength and Conditioning Coach

ABSTRACT THE ROLE OF STRENGTH AND CONDITIONING COACHES IS TO IMPROVE THE PHYSICAL CHARACTERISTICS OF ATHLETES. TO ASSESS IMPROVEMENTS IN PHYSICAL ABILITIES, COACHES MUST OBJECTIVELY INTERPRET TESTING AND TRAINING DATA. THIS ARTICLE INFORMS ACTIVE COACHES ON THE USAGE OF A SIMPLE STATISTICAL METHOD, THE EFFECT SIZE, AND PROVIDES PRACTICAL EXAMPLES OF ITS USE.
Enhancement of GAD Storage Stability with Immobilization on PDA-Coated Superparamagnetic Magnetite Nanoparticles

To improve the storage stability of glutamic acid decarboxylase (GAD), superparamagnetic magnetite (Fe3O4) nanoparticles were synthesized by co-precipitation method and coated with polydopamine (PDA) for GAD immobilization. Dynamic light scattering and transmission electron microscopy were used to determine size of the nanoparticles, which were approximately 10 nm, increasing to 15 nm after PDA-coating and to 20 nm upon GAD binding. Vibrational scanning measurements significantly represented the superparamagnetic behavior of the Fe3O4, and X-ray diffraction analysis confirmed that the crystalline structure before and after coating with PDA and the further immobilization of GAD remained the same. Thermogravimetric analysis and Fourier-transform infrared spectroscopy proved that the PDA-coating on Fe3O4 and further immobilization of GAD were successful. After immobilization, the enzyme can be used with a relative specific activity of 40.7% after five successive uses. The immobilized enzyme retained relative specific activity of about 50.5% after 15 days of storage at 4 °C, while free enzyme showed no relative specific activity after two days of storage. The GAD immobilization on PDA-coated magnetite nanoparticles was reported for the improvement of enzyme storage stability for the first time.
Effect of Ulraviolet Light, pH and Temperature on the Thickening Property of Pectin Extracted from Banana, Orange and Lime Peels

Pectin is a polysaccharide used as rheology modifier in products such as food and beverages. This work assessed the effect of UV light, pH and temperature on the thickening property of pectin extracted from banana, orange and lime peels. Pectin was extracted using alcohol precipitation method and was analyzed using FT – IR spectrometer and GCMS. pH and UV light degradation/depolymerization of pectin solutions were carried out using viscometric and statistical methods. Increase in temperature negatively affects the viscosity of the samples. The viscosity of the banana, orange and lime pectin samples decreased on exposure to UV light for both 30 and 60 days. The observed decrease in the kinematic viscosity of the samples might be attributable to depolymerization which might have occurred with the samples on exposure to the UV light. The viscosity of the samples remained the same at the pH of 4, 7 and 10. Analysis of variance (one way) indicated significant difference in the kinematic viscosity measured to determine the effect of ultraviolet light and temperature (p 0.05). Therefore, exposure to sunlight of pectin containing food drinks can cause decline in the quality of the product. Keywords : Pectin, viscosity, temperature, UV light, pH
Antioxidant Activity of Oat Bran Hydrolyzed Proteins in Vitro and in Vivo

In this thesis research evaluated the potential of oat protein hydrolyzed (OPH) with trypsin (better in vitro antioxidant activity relative to alcalase hydrolysate) to reduce oxidative in vivo. Three different concentrations (1, 10, and 100 mg OPH/g diet) were added to the diet of CD-1 male mice. The animals were divided into five groups, normal diet (ND), high fat (HF), and HF containing 1, 10, and 100 mg OPH/g. The study lasted for 3 weeks after which, mice were scarified. Blood, liver, brain, muscle, lung, and heart tissues collected for analysis. Erythrocytes of mice on 100mg OPH/g had higher (p < 0.05) peroxyl radical scavenging activity compared to HF group. The activity of the antioxidant enzyme superoxide dismutase (SOD) in the liver of mice on HF diet was 13.2% lower compared to the activity of those on the normal diet. Advanced oxidation protein products (AOPP) level in the brain and heart of animals supplemented with 10 mg OPH/g was lowered significantly compared to the rest of the groups. Supplemented with OPH increased (p < 0.05) vitamin C level but did not affect vitamin A or E concentrations in the liver compared to the high fat diet in group. In conclusion, addition OPH to high fat diet reduced oxidative by either increased the total antioxidative capacity of erythrocytes, by reducing protein oxidation or nitric oxide depending on the organ. From these results, it appears that OPH can have beneficiary in conditions associated with oxidative stress.
Natural Deep Eutectic Solvents as Performance Additives for Peroxygenase Catalysis

Natural deep eutectic solvents (NADES) are proposed as alternative solvents for peroxygenase‐catalysed oxyfunctionalization reactions. Choline chloride‐based NADES are of particular interest as they can serve as solvent, enzyme‐stabiliser and sacrificial electron donor for the in situ H2O2 generation. This report provides the first proof‐of‐concept and basic characterisation of this new reaction system. Highly promising turnover numbers for the biocatalysts of up to 200,000 have been achieved.
Adaptive band target entropy minimization: Optimization for the decomposition of spatially offset Raman spectra of bone

We report a novel variant of Band Target Entropy Minimization (BTEM), Adaptive Band Target Entropy Minimization (A-BTEM) that offers an improved ability to accurately decompose mixed spectra obtained from complex multicomponent systems. Several key challenges have existed in the application of the basic BTEM approach to decompose Spatially Offset Raman Spectra (SORS) of bone underneath soft tissues and other multi-layer systems demonstrating high collinearity between the spectra of individual components; these have included instabilities, signal mixing and spectral artefacts which have precluded the reliable use of BTEM in such situations. By using automatic factor selection, an adaptive penalty function in addition to metaheuristic optimization strategies we demonstrate that high quality spectral reconstructions of underlying pure component spectra can be obtained with typical correlation coefficients >0.996. Furthermore, we ascertain the behaviour of A-BTEM with different input datasets, both synthetic and real, displaying varying signal-to-noise ratio, signal composition and numbers of spectra. We thereby identify the multifarious parameter space in the application of A-BTEM and the quality of data required for the most accurate spectral estimates of pure component spectra. [
Botanical‐Inspired 4D Printing of Hydrogel at the Microscale

Botanical systems have evolved the intriguing ability to respond to diverse stimuli due to long‐term survival competition. Mimicking these dynamic behaviors has greatly advanced the developments in wide fields ranging from soft robotics, precision sensors to drug delivery and biomedical devices. However, realization of stimuli‐responsive components at the microscale with high response speed still remains a significant challenge. Herein, the miniature biomimetic 4D printing of pH‐responsive hydrogel is reported in spatiotemporal domain by femtosecond laser direct writing. The dimension of the printed architectures is at the microscale (<102 µm) and the response speed is reduced down to subsecond level (<500 ms). Shape transformation with multiple degrees of freedom is accomplished by taking advantage of pH‐triggered expansion, contraction, and torsion. Biomimetic complex shape‐morphing is enabled by adopting flexible scanning strategies. In addition, application of this 4D‐printed micro‐architecture in selective micro‐object trapping and releasing is demonstrated, showcasing its possibilities in micromanipulation, single‐cell analysis, and drug delivery.
III‐V//Si multijunction solar cells with 30% efficiency using smart stack technology with Pd nanoparticle array

Multijunction (MJ) solar cells achieve very high efficiencies by effectively utilizing the entire solar spectrum. Previously, we constructed a III‐V//Si MJ solar cell using the smart stack technology, a unique mechanical stacking technology with Pd nanoparticle array. In this study, we fabricated an InGaP/AlGaAs//Si three‐junction solar cell with an efficiency of 30.8% under AM 1.5G solar spectrum illumination. This efficiency is considerably higher than our previous result (25.1%). The superior performance was achieved by optimizing the structure of the upper GaAs‐based cell and employing a tunnel oxide passivated contact Si cell. Furthermore, we examined the low solar concentration performance of the device and obtained a maximum efficiency of 32.6% at 5.5 suns. This performance is sufficient for realistic low concentration photovoltaic applications (below 10 suns). In addition, we characterize the reliability of the InGaP/AlGaAs//Si three‐junction solar cell with a damp heat test (85 °C and 85% humidity for 1000 h). It was confirmed that our solar cells have high long‐term stability under severe conditions. The results demonstrate the potential of GaAs//Si MJ solar cells as next‐generation photovoltaic cells and the effectiveness of smart stack technology in fabricating multijunction cells.
Detection of Melanoma Cancer Cell by Designing a SPR Based Biosensor

This paper presents the Nano cavity Implementation of the biosensors in the detection of melanoma cancer tissue. The key challenge in the work is to provide the accuracy for the biosensors and the results are obtained. The developed design shows a path advancing field of medical aspects with the development of Nano plasmon technologies. The Surface Plasmon Resonance (SPR) technology is used, the concept depends on the refractive index of the selected slab layer. The refractive index material of the normal cancer by comparing it with the refractive index of the melanoma cancer tissue in order to know the tissue is cancerous are non-cancerous. Sensitivity for different sensor design is investigated. The overall highest sensitivity obtained is 300 nm/RIU for 1550 nm of wavelength.
Effect of Sodium Carbonate on the Reduction Process of Nickel Slag from Sulawesi

Nickel slag is one of the results of the nickel ore smelting process which is still a waste and has not been used optimally. Considering the amount of nickel slag waste in Indonesia, the effort to utilize it into a more valuable product becomes very important. Therefore, in order to extract the precious metal content in nickel slag, this study aims to analyze the effect of adding sodium carbonate in the reduction process of nickel slag. In this study, the reduction process is carried out using coal as a reducing agent, where the variation of the reduction temperature is 800, 900, and 1000°C; while the variation of the ratio between nickel slag and additives is 1:1, 1:2, and 2:1. The XRD analysis results show that the temperature rise up to 1000 °C and the addition of sodium carbonate will increase the amount of sodium magnesiosilicate up to 29.4% and also hematite up to 25.1%. The same thing happened in samples with a ratio of 1:1 and 1:2 where the amount of sodium magnesiosilicate increased from 29.4% to 30.0% and hematite from 25.1% to 28.8%.