Miracle-dz/UniFAR-FTUs huggingface dataset:
Corporate Relative Valuation Using Heterogeneous Multi-Modal Graph Neural Network

Corporate relative valuation (CRV) refers to the process of comparing a company’s value from company products, core staff and other related information, so that we can assess the company’s market value, which is critical for venture capital firms. Traditional relative valuation methods heavily rely on tedious and expensive human efforts, especially for non-publicly listed companies. However, the availability of information about company’s invisible assets, such as patents, talent, and investors, enables a new paradigm to learn and evaluate corporate relative values automatically. Indeed, in this paper, we reveal that, the companies and their core members can natually be formed as a heterogeneous graph and the attributes of different nodes include semantically-rich multi-modal data, thereby we are able to extract a latent embedding for each company. The network embeddings can reflect domain experts’ behavior and are effective for corporate relative valuation. Along this line, we develop a heterogeneous multi-modal graph neural network method, named HM<inline-formula><tex-math notation="LaTeX">$^{2}$</tex-math><alternatives><mml:math><mml:msup><mml:mrow/><mml:mn>2</mml:mn></mml:msup></mml:math><inline-graphic xlink:href="yang-ieq1-3080293.gif"/></alternatives></inline-formula>, which deals with embedding challenges involving modal attribute encoding, multi-modal aggregation, and valuation prediction modules. Specifically, HM<inline-formula><tex-math notation="LaTeX">$^{2}$</tex-math><alternatives><mml:math><mml:msup><mml:mrow/><mml:mn>2</mml:mn></mml:msup></mml:math><inline-graphic xlink:href="yang-ieq2-3080293.gif"/></alternatives></inline-formula> first performs the representation learning for heterogeneous neighbors of the input company by taking relationships among nodes into consideration, which aggregates node attributes via linkage-aware multi-head attention mechanism, rather than multi-instance based methods. Then, HM<inline-formula><tex-math notation="LaTeX">$^{2}$</tex-math><alternatives><mml:math><mml:msup><mml:mrow/><mml:mn>2</mml:mn></mml:msup></mml:math><inline-graphic xlink:href="yang-ieq3-3080293.gif"/></alternatives></inline-formula> adopts the self-attention network to aggregate different modal embeddings for final prediction, and employs dynamic triplet loss with embeddings of competitors as the constraint. As a result, HM<inline-formula><tex-math notation="LaTeX">$^{2}$</tex-math><alternatives><mml:math><mml:msup><mml:mrow/><mml:mn>2</mml:mn></mml:msup></mml:math><inline-graphic xlink:href="yang-ieq4-3080293.gif"/></alternatives></inline-formula> can explore companies’ intrinsic properties to improve the CRV performance. Extensive experiments on real-world data demonstrate the effectiveness of the proposed HM<inline-formula><tex-math notation="LaTeX">$^{2}$</tex-math><alternatives><mml:math><mml:msup><mml:mrow/><mml:mn>2</mml:mn></mml:msup></mml:math><inline-graphic xlink:href="yang-ieq5-3080293.gif"/></alternatives></inline-formula>.
Maternal Genetic Distance Between Sundanese and Javanese Populations in Indonesia

The study of Austronesian languages classified the Sundanese language within the Malay-Sumbawa group along with Madurese, Aceh, Balinese, Sasak, Sumbawa, and Malay languages. However, The HUGO Pan-Asian SNP Consortium in 2010 reported that the genetic relationship between Sundanese and Javanese people was closer than the one between Sundanese and Malay people. The history of both kingdoms also confirmed the close relationship between Sundanese elites in the west and Javanese elites in the central and east parts of Java. Maternal lineage analysis was done on the mtDNA D-loop region (HVRI and II) from 118 unrelated Sundanese and 33 Javanese probands. We found 12 newly-formed haplotypes (or maternal lineages) as a divergence from one maternal lineage that was characterized by a normal mutation of 186C. These 12 haplotypes were commonly known as the current population of Sundanese and Javanese. Moreover, we also found 11 individual haplotypes that were predicted to be older than the common 12 haplotypes. These older haplotypes were characterized by normal mutations of C64T and C186G. Using a model of K2P, the maternal genetic distance between Sundanese and Javanese populations was 0.12555 or equal to 2190-4622 years of divergence based on the calibration of the mutation rate on both hypervariable regions.
Molecular Characterization and Antibiogram Profiling of Multidrug Resistant Staphylococcus haemolyticus Isolated from Patients with Urinary Tract Infection in Bangladesh

The emergence of antibiotic-resistant bacteria in human is a potential global public health concern. Profiling of antibiotic-resistant bacteria with their antimicrobial susceptibility patterns from Urinary Tract Infections (UTIs) is crucial to guide antibiotic therapy. Herein we report a detailed bacteriological and molecular analysis of Staphylococcus haemolyticus and their antibiogram typing from UTIs. A total of 100 human urine samples of patients with UTIs were collected between January and December 2019 and were subjected to the conventional characterization of bacteria using the standard protocol. Molecular characterization was performed via sequencing followed by phylogenetic analysis. All bacterial strains were examined against thirteen commonly used antibiotics for susceptibility using the Kirby-Bauer disk diffusion method. The overall prevalence of S. haemolyticus in UTI was 26% with female patients having a higher prevalence of UTI (21 out of 26 or 80.76%) than male patients (5 out of 26 or 19.24%). The isolated S. haemolyticus showed 100%, 100%, 88.46%%, 76.93%, 73.08% and 65.39% resistant to penicillin, ampicillin, amoxicillin, erythromycin, ciprofloxacin and tetracycline, respectively. Importantly, S. haemolyticus demonstrated the highest sensitivity to vancomycin (100%), followed by azithromycin (80.76%), amikacin (84.61%), gentamycin (69.23%), levofloxacin (73.08%), ceftriaxone (80.76%) and doxycycline (61.54%). Overall, six variations were noted in S. haemolyticus in which most (5/6) modifications were substitutions and one (1/6) was deletion. These findings imply that mutations in the 16S rRNA gene sequence are the dominant source for species identification and variation in the drug sensitivity pattern against the S. haemolyticus. Phylogenetic analysis of the resultant 16S rRNA indicated that the isolated S. haemolyticus in this study belonged to genus Staphylococcus, but was different from the rest of the available S. haemolyticus isolates in other countries. Multidrug-resistant pathogenic S. hemolyticus is commonly found in urine samples of UTI in human in Bangladesh, which warrants a one-health approach for controlling this emerging ailment.
Fossil Constraints on the Timescale of Parasitic Helminth Evolution

The fossil record of parasitic helminths is often stated to be severely limited. Many studies have therefore used host constraints to constrain molecular divergence time estimates of helminths. Here we review direct fossil evidence for several of these parasitic lineages belong to various phyla (Acanthocephala, Annelida, Arthropoda, Nematoda, Nematomorpha, Pentastomida, Platyhelminthes). Our compilation shows that the fossil record of soft-bodied helminths is patchy, but more diverse than commonly assumed. The fossil record provides evidence that ectoparasitic helminths (e.g., worm-like pentastomid arthropods) have been around since the early Paleozoic, while endoparasitic helminths (cestodes) arose at least during, or possibly even before the late Paleozoic. Nematode lineages parasitizing terrestrial plant and animal hosts have been in existence at least since the Devonian and Triassic, respectively. All major phyla (Acanthocephala, Annelida, Platyhelminthes. Nematoda, Nematomorpha) had evolved endoparasitic lineages at least since the Mesozoic. Interestingly, although parasitism is considered derived within Metazoa, the oldest evidence for Nematoda and Platyhelminthes includes body fossils of parasitic representatives. Furthermore, the oldest fossil evidence of these parasitic lineages often falls within molecular divergence time estimates based on host co-evolution suggesting the fossil record of helminths themselves might be just as good or at least complementary (and less circular in justification) to calibration based on host associations. Data also provide evidence for obvious host switches or extinctions, which cautions against models of pure co-divergence where use of host calibrations to constrain divergence time estimates may be considered.
Cross-Domain Topic Classification for Political Texts

Abstract We introduce and assess the use of supervised learning in cross-domain topic classification. In this approach, an algorithm learns to classify topics in a labeled source corpus and then extrapolates topics in an unlabeled target corpus from another domain. The ability to use existing training data makes this method significantly more efficient than within-domain supervised learning. It also has three advantages over unsupervised topic models: the method can be more specifically targeted to a research question and the resulting topics are easier to validate and interpret. We demonstrate the method using the case of labeled party platforms (source corpus) and unlabeled parliamentary speeches (target corpus). In addition to the standard within-domain error metrics, we further validate the cross-domain performance by labeling a subset of target-corpus documents. We find that the classifier accurately assigns topics in the parliamentary speeches, although accuracy varies substantially by topic. We also propose tools diagnosing cross-domain classification. To illustrate the usefulness of the method, we present two case studies on how electoral rules and the gender of parliamentarians influence the choice of speech topics.
Immunomodulatory effect of the hydroalcoholic extract of Abrus precatorius L. leaves against cyclophosphamide-induced immunosuppression in mice

This study presents the immunomodulatory potential of Abrus precatorius Linn. (Indian wild licorice) leaves. A hydroalcoholic extract of A. precatorius leaves (EAPL) was prepared by maceration. Thirty male mice were divided into five groups as follows: control group, model control group (cyclophosphamide-treated), and three treatment groups (treated with EAPL at doses of 100, 200 and 300 mg/kg, per os, daily for 14 days). Parameters, including hematological, biochemical, organ indices, hemagglutination test (HA titer), delayed-type hypersensitivity (DTH), interleukin-2 (IL-2) level, splenocyte proliferation and liquid chromatography quadrupole time-of-flight mass spectrometry (LC-QTOF-MS) analysis were evaluated. Histopathological examination was carried out for the spleen, kidney and liver. Cyclophosphamide (CPMD)-induced changes in white blood cells, lymphocytes and platelets were improved in the treatment groups. Total protein and albumin levels in the treatment groups were significantly higher. EAPL treatment significantly stimulated splenic T-lymphocytemediated proliferation. Neutrophil adhesion was insignificantly decreased in the model control group compared to the normal control group, which was slightly improved by EAPL treatment. EAPL treatment significantly improved the HA titer and cell-mediated immunity, which is an indication of antibody production. The IL-2 level was significantly higher in the treatment groups that received 200 and 300 mg/kg EAPL. LC-QTOF-MS analysis of EAPL showed the presence of flavonoids, lignans, iridoids and phenolic glycosides. These results suggest that A. precatorius leaves are a good candidate for a new immunomodulatory herbal formulation.
Determination of some nutritional compositions of roe samples of the edible sea urchin Paracentrotus Lividus (Lamarck, 1816) in the Dardanelles (Marmara Sea)

In this study, the nutritional composition of gonad samples of Paracentrotus lividus collected from three different stations in the Sea of Marmara (Dardanelles) and the Northern Aegean Sea, Bozcaada Island during the summer season of 2012 was investigated. As a purpose of the research, the effect of total carotenoids and free radical-scavenging activity assay of three different extracts (methanol, acetone and chloroform extracts) have been determined. Total carotenoids were found to range between 131 and 179 μg/g of sea urchin. The current study shows that the highest inhibition was found as 99.1 (%) in methanolic extract sampled from Tuzburnu (the first station). Macro (Ca, Na, K and Mg) and micro (Cu, Fe, Mn and Zn) mineral composition of urchins was specified by ICP-OES. Results show that sea urchin was found to be rich in total carotenoids, antioxidant capacity, macro and micro minerals.
Pengujian Toksisitas Akut LD50 Infusa Benalu Teh (Scurrula sp.) dengan Menggunakan Mencit (Mus musculus)

Penelitian bertujuan untuk mengevaluasi efek pemberian infusa benalu teh (Scurrula sp.) terhadap toksisitas akut lethal dose 50 (LD50) dan mengkaji perubahan histopatologi hati, ginjal, dan limpa mencit. Sebanyak 30 ekor mencit jantan dan 30 ekor mencit betina dibagi menjadi enam kelompok dan lima ulangan. Mencit percobaan yang tidak diberi infusa benalu teh dikelompokkan sebagai kontrol, sedangkan yang diberi infusa benalu teh dosis 1, 5, 10, 15, dan 20 g/kg BB dikelompokkan sebagai perlakuan. Pemberian infusa benalu teh dilakukan satu kali pada awal penelitian secara oral kemudian mencit diamati gejala klinis, mortalitas, dan bobot badan. Pada akhir penelitian (hari ke-14), mencit percobaan dikorbankan untuk dievaluasi secara histopatologi. Hasil penelitian menunjukkan bahwa pemberian infusa benalu teh pada mencit sampai dengan dosis 20 g/kg BB tidak menimbulkan kematian ataupun gejala klinis spesifik serta pertumbuhan normal. Gambaran histopatologi menunjukkan bahwa pemberian infusa benalu teh pada semua mencit percobaan sampai dengan dosis 20 g/kg BB tidak ditemukan adanya degenerasi maupun nekrosis pada organ hati, ginjal, maupun limpa. Kesimpulan dari penelitian ini menunjukkan bahwa infusa benalu teh dikelompokkan dalam sediaan praktis tidak toksik dan tidak menimbulkan kelainan pada organ hati, ginjal, maupun limpa.
Performance Analysis of Clustered Wireless-Powered Ad Hoc Networks via β-Ginibre Point Processes

We consider a wireless-powered ad hoc network with clustered Power Beacons (PBs). The wireless-powered transmitters (WP-Txs) only activate stochastically deployed PBs within the circles centered at their locations. The PBs transmit radio frequency (RF) signals, which are harvested by the WP-Txs to transmit information to their target receivers. The nodes are modeled as following <inline-formula> <tex-math notation="LaTeX">$\beta $ </tex-math></inline-formula>-Ginibre Point Processes (<inline-formula> <tex-math notation="LaTeX">$\beta $ </tex-math></inline-formula>-GPP), which incorporate repulsion among PBs or active WP-Txs. Lacking analytical mathematical tools to describe the distribution of clustered PBs, we establish lower and upper bounds on the energy outage probability, as well as an approximated expression of it. We then derive the information outage probability, an approximate expression of it by approximating the reduced Palm distribution of <inline-formula> <tex-math notation="LaTeX">$\beta $ </tex-math></inline-formula>-GPP as an inhomogeneous Poisson point process (IPPP), and an analytical approximate expression of it by further ignoring the small-scale fading of interfering WP-Tx links. Finally, the transmission capacity is obtained based on the overall outage probability. The simulation results show that the derived theoretical expressions accurately reflect the performance of the wireless-powered ad hoc networks and the performance gap introduced by approximations is negligible. Transmission capacity optimization based on the derived expressions is also possible and demonstrated.
FLAME DESCRIBING FUNCTION CALCULATIONS OF A TUR- BULENT PARTIALLY-PREMIXED FLAME FROM LES

The present work deals determines of the non-linear heat release response to acoustic forcing of a partially-premixed turbulent flame (known as a Flame Describing Function (FDF)) from high-fidelity Large Eddy Simulations (LES). The target case is a bluff body stabilised partiallypremixed turbulent flame, for which experimental measurements have been carried o ut. The simulations are performed using a low-Mach number solver of the open source CFD toolbox, OpenFOAM, with the combustion modelled using the Partially Stirred Reactor (PaSR) combustion model combining a global one-step chemical reaction mechanism. The unforced/forced reactive flows are simulated in order to validate the computational code. The simulation s capture the unforced flow fields, the flame dynamics and the response of the flame to har monic excitation with good accuracy. On this basis, harmonic acoustic forcing is imposed as a hydrodynamic velocity fluctuation at the inlet whose forcing amplitude and frequency can be varie d independently. By extracting the gain and phase shift of the heat release rate response to h armonic forcing in velocity, we obtain the full FDF. The nonlinearity of the obtained FDF is clearly observed which is of importance to the appearance of limit cycle phenomena. The work thus confir ms that low-Mach number LES, in this case via the open source OpenFOAM, provides a useful tool for characterising the non-linear response of lean partially-premixed turbulent flames to ac oustic forcing.
Brief Overview on Design Techniques and Architectures of SAR ADCs

Successive Approximation Register (SAR) Analog-to-Digital Converters (ADC) seem to become the hottest ADC architecture during the past decade in implementing energy-efficient high performance ADCs. In this overview, we will review what kind of circuit techniques and architectural advances have contributed to place the SAR ADC architecture at its current position, beginning from a single SAR ADC and moving to various hybrid architectures. At the end of this overview, a recently reported compact and high-speed SAR-Flash ADC is introduced as one design example of SAR-based hybrid ADC architecture.
Development of Multi-residue Analysis of 320 Pesticides in Apple and Rice Using LC-MS/MS and GC-MS/MS

A new analytical method has been developed to determine 320 pesticides in apple and rice. The extraction of pesticides was carried out based on QuEChERS sample extraction, and determination was performed using LC-MS/MS and GC-MS/MS. 320 pesticides were selected for experiments. 251 and 110 pesticides among them were analysed by LC-MS/MS and GC-MS/MS, respectively. 41 pesticides of them were analyzed by both GC-MS/MS and LC-MS/MS. Among pesticides analysed by LC, 242 pesticides (96% of total number) in apple and 237 pesticides (94% of total number) in rice showed recoveries in the range of 70~120% with RSD ≤ 20%. In case of pesticides analyzed by GC-MS/MS, 103 pesticides (94% of total number) in apple and 83 pesticides (76% of total number) in rice were successfully validated. These results indicated that LC-MS/MS and GC-MS/MS analysis with the QuEChERS sample preparation can be partly applied to multi-residue pesticides in agricultural products.
Calculation of filtration process in channels

This article provides an analysis and recommendations of the factors that lead to the loss of water as a result of filtration in uncoated canals, rising groundwater levels, deterioration of land reclamation, reduction of canal efficiency coefficient. According to the project data, the part of the Greater Fergana canal from PK-930 to PK-1500 + 10 was built in the type of semi-excavated and natural canal. From PK-930 to PK-1040, the ground level is almost equal to the bottom water level, and the volume of soil discharged in this part of the canal is greater than in other parts. The canal is in the form of a trapezoid and has now changed its shape slightly as a result of a small amount of sedimentation and erosion. In uncoated canals and irrigation systems, there are a number of connections to perform the basic filtration calculation. These bonds are obtained according to Darcy’s law, filtration for homogeneous and isotropic soils. Using the available data, it is possible to determine the depression curve in canals and irrigation systems for all cases, the points that form its curvature, and the filtration rate that occurs in it. It consists of determining the filtration rate (q) of the system at a length of 1 pogm and the filtration coefficient (k) of the soil.
Expression of ACE2 in the Intact and Acutely Injured Kidney

Visual Abstract Abstract Key Points The healthy kidney prominently expresses angiotensin-converting enzyme 2 (ACE2) mRNA, protein, and activity, with ACE2 protein abundantly displayed in proximal tubules. Renal ACE2 expression decreases after ischemic AKI but is induced by LPS in a heme oxygenase-1-dependent manner. ACE2 induction/angiotensin (1–7) and angiotensin (1–7) may offer therapeutic approaches for AKI without or with coronavirus disease 2019, respectively. Background The actions of angiotensin-converting enzyme 2 (ACE2) oppose those of the renin-angiotensin-aldosterone system. ACE2 may be a cytoprotectant in some tissues. This study examined ACE2 expression in models of AKI. Methods ACE2 mRNA and protein expression and ACE2 activity were assessed in murine ischemic AKI. Renal ACE2 mRNA expression was evaluated in LPS-induced AKI in wild-type (C57BL/6J) mice, in heme oxygenase-1+/+ and heme oxygenase-1−/− mice, and after unilateral ureteral obstruction (UUO) in wild-type mice. The effect of sex and age on renal ACE2 protein expression was also assessed. Results In ischemic AKI, ACE2 mRNA and protein expression and ACE2 activity were reduced as compared with such indices in the intact kidney. In ischemic AKI, ACE2, which, in health, is prominently expressed in the tubular epithelium, especially proximal tubules, is decreased in expression in these segments. Decreased ACE2 expression in AKI did not reflect reduced GFR, because ACE2 mRNA expression was unaltered after UUO. LPS induced renal ACE2 mRNA expression in wild-type mice, but this effect did not occur in heme oxygenase-1–deficient mice. In ischemic and LPS-induced AKI, renal expression of the Mas receptor was increased. In the intact kidney, renal ACE2 protein expression decreased in female mice as compared with male mice, but was unaltered with age. Conclusion We conclude that renal ACE2 expression is decreased in ischemic AKI, characterized by decreased GFR and abundant cell death, but is upregulated in LPS-induced AKI, an effect requiring heme oxygenase-1. Determining the significance of ACE2 expression in experimental AKI merits further study. We suggest that understanding the mechanism underlying ACE2 downregulation in AKI may offer insights relevant to COVID-19: ACE2 expression is downregulated after ACE2 mediates SARS-CoV-2 cellular entry; such downregulation is proinflammatory; and AKI commonly occurs and determines outcomes in COVID-19.
Supraduodenal and Right Gastric Arteries Originating from A Common Trunk: A Rare Anatomical Variant

Knowledge of the anatomic variations of the supraduodenal artery (SDA) and right gastric artery (RGA) is necessary to reduce the procedure time and radiation exposure dose, as well as to avoid unexpected complications of catheter placement before hepatic arterial infusion chemotherapy. The SDA and RGA most commonly arise from the gastroduodenal artery (GDA) and the proper hepatic artery, respectively; however, they can branch from the left hepatic artery (LHA). In addition, the SDA frequently anastomoses with the RGA and occasionally with the GDA. We observed a rare anatomic variant of SDA and RGA originating from the LHA as a common trunk. The patient also had a variant of SDA communicating with the GDA. It is important for interventional radiologists to be aware of these variations.