Miracle-dz/UniFAR-FTUs huggingface dataset:
The Predictive Validity of the Battelle Developmental Inventory as a Measure of Adaptive Behavior: A 2-3 Year, Longitudinal Comparison With the Scales of Independent Behavior

vi PROBLEM STATEMENT . l REVIEW OF THE LITERATURE . 4 Preschool Development . 4 Adaptive Behavior . 7 Predictive Validity . 10 Sources of Variance . 11 Previous Research on the BDI . 13 PURPOSE AND OBJECTIVES . 15 METHOD . 16 Subjects . 16 Procedure . 16 Instruments . 17 RESULTS . 23 All Subjects . 23 Shared Variance . 25 Coefficients for Two Age Groups . 26 Discriminant Analysis . 30 DISCUSSION . 31 All Subjects . 31 Coefficients for Two Age Groups . 33 Comparison with Other Research . 37 Practical Implications of the Study . 37 Study Limitations . 38 Implications for Future Research . 39 Summary . 39
Orphan drugs in glioblastoma multiforme: a review

: Glioblastoma multiforme (GBM) is the most common and deadly brain tumor in adults. The incidence of GBM in the USA and Europe is 2–3 per 100,000. By definition, an orphan disease affects up to 200,000 persons in the USA (one in every 1,500). A search was made in the US Food and Drug Administration orphan drug listing. In addition, a PubMed search of orphan drugs designated for GBM or high-grade glioma was performed, followed by a search for clinical studies in GBM with orphan drugs designated for other indications. This included cytotoxic chemotherapy and targeted agents. Thirteen drugs with orphan designation for the treatment of glioblastoma, high-grade glioma, or primary malignant brain tumors were identified. In addition, 16 drugs with orphan designation for other indications were identified to have been evaluated in clinical studies of GBM. The efficacy data from the clinical studies is presented. A few agents have been approved by the US Food and Drug Administration for the treatment of high-grade gliomas following orphan drug designation, but most have failed to reach the market. However, a few patients may have benefited from receiving developmental agents within clinical trials. Biomarkers for selection of these patients may result in more success in the field of personalized medicine.
Using Function Point Analysis and COSMIC for Measuring the Functional Size of Real-Time and Embedded Software: a Comparison

Function Points Analysis and the COSMIC method are very often used for measuring the functional size of programs. The COSMIC method was proposed to solve some shortcomings of Function Points, including not being well suited for representing the functionality of real-time and embedded software. However, little evidence exists to support the claim that COSMIC Function Points are better suited than traditional Function Points for the measurement of real-time and embedded applications. To help practitioner choose a method for measuring real-time or embedded software, some evidence of the merits and shortcomings of the two methods is needed. Accordingly, our goal is to compare how well the two methods can be used in the functional measurement of realtime and embedded systems. To this end, we applied both measurement methods to the situations that occur quite often in real-time and embedded software and are not considered by standard measurement practices. Our results indicate that, overall, COSMIC Function Points are better suited than traditional Function Points for measuring characteristic features of real-time and embedded systems.
Full characterization of binary-lens event OGLE-2002-BLG-069 from PLANET observations

We analyze the photometric data obtained by PLANET and OGLE on the caustic-crossing binary-lens microlensing event OGLE-2002-BLG-069. Thanks to the excellent photometric and spectroscopic coverage of the event, we are able to constrain the lens model up to the known ambiguity between close and wide binary lenses. The detection of annual parallax in combination with measurements of extended-source effects allows us to determine the mass, distance and velocity of the lens components for the competing models. While the model involving a close binary lens leads to a Bulge-Disc lens scenario with a lens mass of M=(0.51 +- 0.15) M_sol and distance of D_L=(2.9 +- 0.4) kpc, the wide binary lens solution requires a rather implausible binary black-hole lens (M >=126 M_sol). Furthermore we compare current state-of-the-art numerical and empirical models for the surface brightness profile of the source, a G5III Bulge giant. We find that a linear limb-darkening model for the atmosphere of the source star is consistent with the data whereas a PHOENIX atmosphere model assuming LTE and with no free parameter does not match our observations.
MIMO Wavelet Transform using Optimized Successive Interference Cancellation

This research introduces a physical layer technique to enhance the capability of MIMO wavelet systems by using successive interference cancellation which enables the receiver to decode simultaneous data packets. The received power of the data packet was introduced to further optimize the receiver’s decision capability. Results show that a Discrete Wavelet Transform-based MIMO system with interference cancellation provides a performance gain as compared to a theoretical 2x2 MIMO channel in terms of BER vs. SNR performance. The performances of two different techniques have been evaluated in this work using interference cancellation both with and without consideration of received signal power.
Type of action : RIA D 5 . 1 : Machine learning algorithms development and implementation

This deliverable reports on research enabling the efficient management of dense wireless networks. The work investigates automatizing aspects of wireless networks with the help of machine learning algorithms. Each section of the deliverable reports on a D5.1: Machine learning algorithms development and implementation © eWINE Consortium 2016-2018 Page 2 of 72 problem being solved and explains how the solution is included in the corresponding showcase. The provided solutions use both advanced and more traditional machine learning algorithms. An investigation on how to approach feature engineering and class unbalance challenges to finally deliver performant prediction and classification technology is also included. The software tools and datasets developed while carrying out the studies form part of the eWINE Intelligence Toolbox, will be released as open source in the Wireless Testbed Academy GitHub repository and used in the eWINE Grand Challenge.
An Evaluation of Redmapper ’ s Galaxy Cluster Centering Algorithm

The goal of this project was to evaluate Redmapper’s centering algorithm and to investigate possible ways of improving its centering. To accomplish this, I visually selected brightest cluster galaxies (BCGs) for roughly 350 galaxy clusters and compared my selected BCG with that selected by Redmapper. The centering success rate for these clusters was much better than expected, with only « 5% of clusters being miscentered. However, we found that an additional 15% of Redmapper clusters were either unusually diffuse clusters or perhaps substructures of larger nearby clusters, suggesting that this may be an issue caused by the cluster finding algorithm, not the centering.
Development and College Adjustment of LGBT College Students Perceived Discrimination and Social Support: The Influences on Career

The experiences of lesbian, gay, bisexual, and transgender (LGBT) college students have been an increasing area of interest in the realm of career development in recent years. Although career theorists have posited the importance of considering context when examining career development, the specific variables related to LGBT individuals’ experiences warrant further investigation. The aim of this study was to examine how the perception of discrimination and social support related to career development and college adjustment in an LGBT undergraduate student sample. Two multiple regression analyses demonstrated that perceived discrimination and social support contribute to vocational indecision and college adjustment. The implications for career counselors and other professionals working with this student group are discussed. 1 Psychology Department, Towson University, Towson, MD, USA 2 Psychology Department, University of Tennessee, Knoxville, Knoxville, TE, USA 3 Harvard University Health Services, Cambridge, MA, USA Corresponding Author: Christa K. Schmidt, Psychology Department, Towson University, 8000 York Road, Towson, MD 21252, USA Email: ckschmidt@towson.edu Journal of Career Development 000(00) 1-17 a Curators of the University of Missouri 2010 Reprints and permission: sagepub.com/journalsPermissions.nav DOI: 10.1177/0894845310372615 http://jcd.sagepub.com
Towards Near Zero Energy Home

In the context of building design, as investment in the built-environment continues to grow, the requirement to deliver low-energy buildings will become ever more pressing as natural resources dwindle and consumer energy costs increase. Energy efficiency awareness and regulations continue to rise in the Gulf Cooperation Council (GCC) countries but the majority of building stock of which the larger share in energy consumption has not been designed for energy efficiency. The design and construction of buildings in hot humid climates require high-energy consumption typically for air conditioning due to higher thermal loads. Regionally, there is a rising concern on the current rate of energy consumption due to air conditioning. The global sustainability assessment system (GSAS), a performance-based system raised the bar of efficient design by the development of stringent energy passive design benchmarks on the thermal cooling need in buildings. This chapter introduces the simulation measures undertaken to reduce the cooling need using a ‘showcase’ house or the ‘near Zero Energy Home’ (nZEH), which is currently under construction. The chapter presents and discusses the Be Lean, Be Clean and Be Green strategies that used to reduce the cooling demand by more than 80% and the overall energy consumption by 75%.
Understanding Consumer Conversations Around Ads in a Web 2.0 World

User-generated online content poses a problem when it takes the form of advertising. Consumer-generated advertising challenges researchers and practitioners to understand consumers' articulated responses to ads and to the responses of other consumers, as well as the implications these may have for the brand. Traditional research methods such as viewer-response testing may be limited when the viewer becomes part of the conversation. This exploratory study attempts to interpret the conversations consumers have around consumer-generated ads using the comments they have posted to each ad's Web page. We show how conversations around ads can be mapped and interpreted, and then develop a typology of consumer-generated ad conversations. We discuss managerial implications of our findings, outline the limitations of the technique used, and trace avenues to extend the research.
Renewable Mobility in Smart Cities: Cloud-Based Services

Providing efficient, sustainable and personalized mobility services in urban environments that combine a spectrum of transport modes (e.g., public transport, electric vehicles, vehicle sharing, low energy and/or emission routes) constitutes a great challenge. In this work, we present MOVESMART, a holistic approach (and integrated platform) for the provision of renewable personal mobility services, leveraging crowd-sourcing data, tools for collecting real-time information by multimodal travelers, and traffic prediction mechanisms. MOVESMART guarantees real-time responses to renewable (on-demand) mobility queries for efficient multi-modal route planning that are time-dependent as well as sensitive to aperiodic incidents and traffic prediction forecasts. This paper focuses on the cloudbased (backend) services of the MOVESMART platform.
Growth paths for suckler bulls slaughtered at 19 months of age: a meat quality perspective

This experiment aimed to assess the effect of different indoor winter growth rates (WGR) followed by different concentrate supplementation levels at pasture on meat quality of 90 bulls. During the first winter, bulls were offered grass silage ad libitum and either 3 kg (WGR3) or 6 kg (WGR6) of concentrates. After turn-out to pasture, bulls were offered: grass without supplementation (PO), grass plus 0.2 predicted dry matter intake (DMI) as concentrates (PL) or grass plus 0.4 predicted DMI as concentrates (PH). After finishing, colour, chemical composition (unaged), instrumental texture and sensory characteristics (14 days of ageing) of longissimus thoracis were measured. WGR6 bulls had heavier carcasses than WGR3 bulls. There was an interaction between WGR and supplementation for instrumental texture and redness (a). Within WGR3, PO beef was the most tender, whereas within WRG6, PL was the most tender. However, these differences were not detected by the sensory panel. Within WGR3, redness was the lowest for PL, whereas within WRG6, PO was the least red. No differences were found for chemical composition. The multivariate analysis highlighted WGR as the main variable affecting meat quality characteristics. In conclusion, variations in growth path exerted minor effects on appearance and instrumental texture which did not affect the perception of bull beef by a trained sensory panel.
Pituitary Self-priming Actions of Gonadotropin-releasing Hormone Kinetics of Estradiol ' s Potentiating Effects on Gonadotropin-releasing Hormone-Facilitated Hormone and Follicle-stimulating Hormone Release in Healthy Postmenopausal Women I Luteinizing

We examined the kinetically distinct characteristics of estradiol's effects upon pituitary luteinizing hormone (LH) and folliclestimulating hormone (FSH) release in response to pulses of exogenous gonadotropin-releasing hormone (GnRH) in healthy postmenopausal individuals. The putative self-priming actions of GnRH on LH and FSH release were tested by intravenous injections of equal paired doses of GnRH (10 jig) before and after 1, 5, 10, and 30 d of pure estradiol-17,6 delivery via an intravaginal silastic ring. Self-priming actions of GnRH, as defined by heightened gonadotropin release in response to the second pulse of GnRH compared with the first, were completely absent in the hypoestrogenemic state. However, estradiol administration unmasked GnRH self-priming in a time-dependent fashion, with maximal expression after 5 and 10 d of steroid replacement, followed by attenuation by 30 d. Since estradiol's modulation ofGnRH action was expressed differentially on LH and FSH release, we suggest that such facilitation of GnRHstimulated pituitary LH and FSH release may provide an additional mechanism for dissociated secretion of gonadotropic hormones in health or disease.
Identification of Osmoresponsive Genes in Escherichia coli : Evidence for Participation of Potassium and Proline Transport Systems in Osmoregulation

Mu dl(Ap lac)-generated operon fusions were used in the identification of genes in Escherichia coli whose transcriptional expression is altered by changes in the osmolarity of the growth medium. One such osmoresponsive gene, designated osrA, was induced 400-fold when the osmolarity of the medium was increased with the addition of either ionic or neutral impermeable solutes but was not induced with glycerol, which is freely permeable across the cell membrane. osrA was mapped to 57.5 min and was shown to be transcribed clockwise on the E. coli chromosome. The ability of small concentrations of L-proline to promote the growth of E. coli in high-osmolar medium was shown to have been specifically lost in osrA mutants; other lines of evidence were also obtained to support the notion that osrA codes for an osmoresponsive L-proline transport system and is homologus to proU in Salmonella typhimurium. A second osmoresponsive operon identified was kdp, which codes for an inducible K+-transport system in E. coli. kdp expression was elevated 12-fold when the osmolarity of the growth medium was increased with the addition of impermeable ionic solutes but not neutral solutes; furthermore, osmoresponsivity of kdp expression was demonstrable only in K+-limiting media. kdp mutants were able to grow normally in high-osmolar media, but strains defective in both kdp and trkA (a gene for a second major K -transport system) displayed an osmosensitive phenotype. The results suggest that transport systems for L-proline and K+, specified by osrA (proU) and kdp, respectively, play independent and important roles in osmoregulation in E. coli. A third osmoresponsive gene that was identified was lamB, which codes for an outer membrane protein for maltodextrin transport and A phage adsorption; its expression was reduced fourfold with increase in the osmolarity of the growth medium.
2622 Arterial Compliance of the Middle Cerebral Artery Measured with Short Inversion Time Pulsed Arterial Spin Labelling

Target audience Researchers and clinicians interested in non-invasive assessment of arterial compliance of cerebral arteries. Introduction Arterial compliance (AC) is a potential marker of cerebral vascular disease and describes the relationship between a change in arterial blood volume (ΔaBV) arising from a change in blood pressure, such as between systole and diastole [1]. Pulsed arterial spin labelling (PASL) could offer a non-invasive way to measure aBV if used with short inversion times (TI < 1000 ms) such that the labelled blood remains in large arteries [2]. However, differences in dispersion and arrival time of the labelled blood due to the pulsatility of blood flow confound comparison of arterial signal using ASL [2]. Here, we aim to calculate AC of the middle cerebral arteries (MCA) by measuring systolic and diastolic aBV with short TI pulsed ASL while taking the differences in label kinetics between the cardiac phases into account. Methods Multi-inversion time PICORE PASL acquisitions were performed on seven healthy volunteers (age 25.6 ± 1.3 years). Seven inversion times (TIs) were acquired (250 – 850ms, spacing 100 ms). A QUIPSS II [3] cut off of the label was applied at 700 ms for inversion times > 700 ms. Images were acquired with a spiral gradient echo sequence (TE=2.7 ms, TR=1400 ms, 80 tag-control pairs, 14 slices, slice gap 1 mm, voxel size 3.5x3.5x7 mm). A single TR image was obtained with the same acquisition parameters but without labelling, to obtain the equilibrium magnetisation of cerebrospinal fluid (M0,CSF). The cardiac cycle was measured by finger plethysmography. Brachial artery blood pressure (BP) was measured noninvasively with an MRI compatible blood pressure cuff during every ASL scan (seven times in total for each participant).
Models of red giants in the CoRoT asteroseismology fields combining asteroseismic and spectroscopic constraints

Context. The availability of asteroseismic constraints for a large s ample of red giant stars from the CoRoT and Kepler missions paves the way for various statistical studies of the seismic prope rties of stellar populations. Aims. We use the first detailed spectroscopic study of 19 CoRoT red- giant stars (Morel et al 2014) to compare theoretical stella r evolution models to observations of the open cluster NGC 6633 and field stars. Methods. In order to explore the effects of rotation-induced mixing and thermohaline instability, we compare surface abundances of carbon isotopic ratio and lithium with stellar evolution pr edictions. These chemicals are sensitive to extra-mixing on the red-giant branch. Results. We estimate mass, radius, and distance for each star using the seismic constraints. We note that the Hipparcos and seismic distances are different. However, the uncertainties are such that this may not be significant. Although the seismic distances for the cluster members are self consistent they are somewhat larger than the Hipparcos distance. This is an issue that should be considered elsewhere. Models including thermohaline instability and rotation-induced mixing, together with the seismically determined masses can explain the chemical properties of red-giants targets. However, with this sample of stars we cannot perform stringent tests of the current stellar models. Tighter constraints on the physics of the models would require the measurement of the core and surface rotation rates, and of the period spacing of gravity-dominated mixed modes. A larger number of stars with longer times series, as provided by Kepler or expected with Plato, would help for ensemble asteroseismology.
Concentrations of minerals in pig feed ingredients commonly used in China1

Abstract Mineral concentrations were determined in 13 different feed ingredients commonly used in swine diets. Ingredients included corn and 4 corn co-products: corn gluten feed, corn gluten meal, corn germ meal, and corn distillers dried grains with solubles (DDGS). Wheat, wheat bran, and wheat shorts were also included, and 5 oilseed meals including soybean meal, rapeseed meal, sunflower meal, cottonseed meal, and peanut meal were used as well. Corn grain contained 88.7% dry matter (DM) and 0.46% K (DM basis). Greater concentrations of DM, ash, Ca, P, nonphytate P, Cu, Fe, Mn, and Zn were observed in corn gluten feed, corn DDGS, and corn germ meal compared with corn grain (P < 0.05). In general, minerals in corn DDGS were approximately three times greater than in corn grain and about 90% of the total P in corn DDGS was in the nonphytate bound form. Corn gluten meal had the least concentrations (P < 0.05) of most minerals, but the greatest (P < 0.05) concentrations of Fe (373.55 mg/kg, DM basis), Cu (11.88 mg/kg, DM basis), and Se (0.92 mg/kg, DM basis). On a DM-basis, concentrations of DM, Ca, P, phytate bound P, and Fe in wheat grain were 88.2%, 0.10%, 0.34%, 0.16%, and 53.48 mg/kg, respectively. Wheat bran contained more (P < 0.05) K, Mg, Cl, Fe, Zn, and Mn compared with wheat and wheat shorts. On a DM-basis, 2.72% K was observed in soybean meal, which was more (P < 0.05) than in the other oilseed meals. However, rapeseed meal had the greatest (P < 0.05) concentration of ash (9.37%), Ca (1.01%), P (1.05%), and Fe (526.49 mg/kg) among the oilseed meals, but only 16.2% of the total P in rapeseed meal was non-phytate P. In contrast, more than 50% of the P in soybean meal and peanut meal was non-phytate P. The least (P < 0.05) concentration of Cu (6.73 mg/kg, DM basis) was observed in rapeseed meal and the greatest (P < 0.05) concentration (32.75 mg/kg) was analyzed in sunflower meal. Concentrations of most minerals in soybean meal, rapeseed meal, sunflower meal, cottonseed meal, and peanut meal varied considerably compared with published values. In conclusion, the concentration of minerals in 13 commonly used feed ingredients were analyzed and results indicated considerable variation among and within feed ingredients for most minerals, which for some minerals may be a result of differences in minerals in the soil in which the ingredients were grown, but processing likely also contributes to differences among ingredients.
Fluence Field Modulated CT Potential for Dose and Noise Optimization in Thoracic Imaging Applications

Recently, awareness regarding the potential risks of radiation dose due to computed tomography (CT) scans has been raised both in the general public, via reports in mainstream media, as well as among medical practitioners and physicists. A notable example of the former is the article “How Dangerous Are CT Scans,” which appeared in Time magazine (Guthrie, 2008). The latter has been evidenced in North America most significantly through the widespread campaigns Image Gently and Image Wisely, which have the general mandate of providing education on how to limit unnecessary dose to pediatric and adult patients respectively. Fluence Field Modulated CT