Miracle-dz/UniFAR-FTUs huggingface dataset:
Some geometric topics of Jackson ’s (p,q)- derivative convoluted with a Subclass of convex function with negative coefficients

In the present work, a new subclass ℘ (_p,q^(δ,k)) (τ ,η) of convex functions with negative coefficients by derivative operator Υ_(τ,p,q)^(δ,k) , considered coefficient inequalities, growth and distortion theorem, closure theorem, and some properties of sundry functions pertinence in class considered. So get radii of close-to-convexity for function pertinence in to class ℘ (_p,q^(δ,k))(τ,η) . Moreover, an integrated way inequality resolve for functions pertinence in class ℘ (_p,q^(δ,k))(τ,η) .
Seasonal Volatility in Agricultural Markets: Modelling and Empirical Investigations

We introduce a multi-factor stochastic volatility model based on the CIR/Heston volatility process that incorporates seasonality and the Samuelson effect. First, we give conditions on the seasonal term under which the corresponding volatility factor is well-defined. These conditions appear to be rather mild. Second, we calculate the joint characteristic function of two futures prices for different maturities in the proposed model. This characteristic function is analytic. Finally, we provide numerical illustrations in terms of implied volatility and correlation produced by the proposed model with five different specifications of the seasonality pattern. The model is found to be able to produce volatility smiles at the same time as a volatility term-structure that exhibits the Samuelson effect with a seasonal component. Correlation, instantaneous or implied from calendar spread option prices via a Gaussian copula, is also found to be seasonal.
A New Kind of Integral Cryptanalysis for the Round-reduced AES

— AES is the mostly used block cipher nowadays. At CRYPTO 2016, Sun et al. proposed the first 5-round distinguisher of the AES [19]. However, it is somewhat closely related with the keys and hardly be used to mount a key recovery attack. Later in FSE 2016 [12] and EUROCRYPT 2017 [13], the distinguisher was improved. In this paper, by combining the techniques proposed by Sun et al. at CRYPTO 2016, we find a new 3-round integral distinguisher of AES which is closely related with the round keys. Then, based on the new distinguisher, we develop new techniques and give a new integral cryptanalysis for the round-reduced AES. We believe this may give new insight on the security of the AES.
Process for an efficient lentiviral cell transduction

Abstract The combination of lentiviruses with techniques such as CRISPR-Cas9 has resulted in efficient and precise processes for targeted genome modification. An often-limiting aspect, however, is the efficiency of cell transduction. Low efficiencies with particular cell types and/or the high complexity of lentiviral libraries can cause insufficient representation. Here, we present a protocol that yielded substantial increases in transduction efficiency in various cell lines in comparison to several other procedures.
The molecular response of Lactobacillus plantarum to intestinal passage and conditions

Lactobacillus plantarum is a lactic acid bacterium (LAB) that is encountered in many environmental niches, including dairy, meat and a variety of vegetable fermentations. Next to the occurrence of L. plantarum in our diets, this microbe is frequently encountered as a natural inhabitant of the gastrointestinal tract (GI-tract). This thesis describes the identification and functional analysis of L. plantarum promoters and genes that play a role during intestinal passage of this LAB. During these studies the mouse GI-tract and in vitro studies were utilized as models for the human situation. Three main strategies that allow the identification of conditionally active genes have been implemented in L. plantarum , namely an in vitro screen to trap bile-inducible promoters, DNA micro-array technology to identify mRNAs that are up-regulated in the presence of bile, and a resolvase-based in vivo expression technology (R-IVET) screen to select promoters that are induced in the GI-tract of a mouse model system. Matching of the genes identified with these three strategies revealed two genes, encoding an integral membrane protein and an argininosuccinate synthase, which appeared to be induced by bile in vitro as well as in vivo in the mouse GI-tract. As the duodenum is the intestinal site of bile release, expression of these two genes at this specific location in the host's GI-tract was investigated using quantitative reverse transcription PCR . The results demonstrated that the expression levels of these two genes were dramatically increased in L. plantarum cells isolated from the mouse duodenum relative to cells grown on standard laboratory medium. Furthermore, gene disruption mutants were constructed in 12 of the in vivo induced ( ivi ) genes identified by the R-IVET screen. The effect of the mutations on the survival and persistence of L. plantarum were investigated using quantitative PCR to monitor the relative population dynamics of the group of mutants in faecal samples after passage through the GI-tract of mice. These data indicate that the products of three of the disrupted genes (an orphan IIC transport component of a cellobiose PTS system, an extracellular protein that contains an LPQTNE motif involved in anchoring of this protein to the bacterial cell wall , and a copper transporting ATPase) play a key-role in the survival and/or persistence of L. plantarum during passage of the GI-tract. Overall, the results described in this thesis represent a first step towards molecular elucidation of the behavior of L. plantarum in a highly complex and inaccessible niche like the GI-tract. These results contribute to the development of eventual molecular models that describe GI-tract behavior of LAB, which are fundamental for the explanation of probiotic effects associated with these microbes and related species at the molecular level.
Comparative evaluation of air, freeze and fluidised bed drying for Solid State Fermented (SSF) lactic cultures

The present investigation was intended to compare the optimized Solid State fermented (SSF) lactic culture by using various drying preservation methods such as air drying, freeze drying and fluid bed drying. The SSF fermented cultures were dried with the moisture reduction from initial moisture of 96% to 81, 72 and 54% using air drying at 20C, 25C and 30C temperatures respectively. The drying was done openly, hence, led to aerobic spore contamination in SSF lactic cultures, thus the method of air drying of SSF lactic cultures became limited. Further, freeze drying was carried out to dry SSF cultures on black gram dhal in which viable counts were reduced from 8.59 to 7.15 log 10 cfu/g, 9.08 to 7.23 log 10 cfu/g and 9.50 to 7.47 log 10 cfu/g in dahi, yoghurt and acidophilus cultures respectively. Freeze drying on an average reduced the viable lactic accounts by 1.7 log counts mean while drying of 11 g of wet SSF lactic culture took 8 h to dry with moisture content of 11 per cent. Fluidized bed drier was found as suitable method to dry SSF lactic cultures at ambient temperature (25±1C) for period of 1, 1.5 and 2 h. Out of the drying period of 1.5 h was found suitable to retain maximum viability with a satisfactory moisture content compared to 1 h and 2 h of drying. The viable counts of SSF lactic cultures maintained after fluid bed drying for 1.5 h were 8.33, 8.85 and 9.34 log 10 cfu/g. Among the air drying, freeze drying and fluid bed drying, the best method seemed to be the fluid bed drier to dry SSF lactic cultures on supplemented black gram dhal with respect to higher viability and less moisture retainment compared to other two.
Evaluation of Antioxidant Activity of Developed Instant Soup Mixes using Vegetable Leaf Powders from Unconventional Greens

Green leafy vegetables had enormous nutritive potential and can be used in the prevention of radical-induced diseases. About 600 species constitute the global diversity in vegetable crops but only one fourth is utilized as a major vegetable crop and rest are named International Journal of Current Microbiology and Applied Sciences ISSN: 2319-7706 Volume 9 Number 1 (2020) Journal homepage: http://www.ijcmas. com
The shell bone histology of fossil and extant marine turtles revisited

Modern turtles exhibit a broad scope of ecological adaptations, including coastal marine and pelagic habitats, and, during their evolutionary history, turtles repeatedly exploited the aquatic environment as well. Although some pleurodiran clades also ventured into the marine realm, it is the cryptodires that did so most extensively. Among those, three major radiation phases are distinguished, with the first phase consisting of basal eucryptodiran taxa inhabiting littoral or near costal environments (Late Jurassic, Europe); the second phase including more open marine chelonioids (starting in the late Early Cretaceous, mainly North America and Eurasia); and the third phase (starting in the Palaeocene/Eocene, global distribution) including the highly-nested chelonioids, such as the modern cheloniid and dermochelyid turtles and closest relatives. A review of previously published as well as unpublished data of shell microstructures of these groups and those of some of the earliest aquatic turtles from the Middle Jurassic, Heckerochelys romani and Eileanchelys waldmani, show that bones are strongly influenced functionally as a result of life spent in an aquatic medium, whereas there are little to no characters of systematic value in the bones. We confirm the general tetrapod pattern that pelagic forms tend to show osteoporotic-like shell structures and neritic forms tend to have more bone ballast, especially by retaining a thickened external compacta. © 2014 The Linnean Society of London, Biological Journal of the Linnean Society, 2014, 112, 701–718.
An Analysis of Theory of Organisational Typologies and their Application in Higher Education Institutional Settings

This research examined the different theories of organisational typologies and their conceptualised application to higher education institutions. The paper is divided into two main parts. The first part is the literature review which discusses each of the organisational typologies and their basic characteristics. Specific examples are also given for each of organisational typology alongside the proponent of each type. Four different types of typologies presented by Miles and Snow [1], Burns and Stalker [2], Morgan [3] and Hoy and Miskel [4] are discussed in the review section. The second part practically synthesised how each of the organisational typologies could apply to the higher educational institutions. A mind map was created to prove how a specifically higher institution may be classified as a ‘defender’ type of organisation.
Revelações de mulheres em narrativas: reflexões sobre HIV e gênero no campo da Linguística Aplicada

Understanding identity as a process of symbolic and discursive production (SILVA, 2014) through social practices and interactions, this article is part of the master's research (2015) that was justified by the historical silencing of women's identity construction in relationships of power. Thus the objective of this text is to present the life experiences of women, research participants, in a life period prior to living with HIV. The theoretical references on social identities of gender, applied linguistics and HIV are: Borba (2008, 2010) and Norton (2010). The qualitative narrative methodology was guided by the three-dimensional space Clandinin and Connelly (2000) for the analysis of autobiographical narratives of women living or living with HIV. As a result, it was found that the social identities, revealed in the women narratives before being infected with HIV, had an affective bond with the male figure and beliefs that domestic chores and caring for the other were their duties. They were in reconstruction in the process of reflection about their social relations in the affective, economic, social and personal fields. Thus, it was possible to conclude that the fact of being a woman intersects with the process of construction and reconstruction, then as a part of living when talking about HIV, it intertwined with people's social relations and practices, as well as with gender relations. Given the above, this article is composed by the introduction, social gender identities, narrative research, narratives of women who live with HIV and final considerations.
Improvement of Germ Line Transmission by Targeting β‐galactosidase to Nuclei in Transgenic Mice

The Escherichia coli lacZ gene has frequently been used as a reporter in cell lineage analysis, in determining the elements regulating spatial and temporal gene expression, and in enhancer/gene trap detection of developmentally regulated genes. However, it is uncertain whether lacZ expression affects eukaryotic cell growth and development. By using a gene trap, we previously isolated the promoter, Ayu1, which is active in ES cells and in several tissues including the gonads. We used this promoter and the nuclear location signal of the SV40 large T gene to locate β‐galactosidase either in the cytoplasm or the nucleus. Transgenic lines containing β‐galactosidase in the cytoplasm of a wide variety of cell types did not transmit the transgene to their offspring. In contrast, transgenic mice, containing β‐galactosidase in the nucleus, did transmit the transgene successfully. Interestingly, lacZ expression in the brain was more restricted when β‐galactosidase activity was detected in the cytoplasm. These data suggested that cytoplasmic β‐galactosidase affects certain developmental processes or gametogenesis resulting in transmission distortion of the transgene, and that this effect can be reduced by targeting β‐galactosidase to the nucleus. We also found that Ayu1‐driven lacZ expression in the duodenum of adult transgenic mice was sexually dimorphic, being positive in females and negative in males.
Enhancement of Surface Crack Density Produced by EDM Using Hybrid Machining

The present work is aimed to improve the surface cracks density of electrical discharge machining (EDM) by Electrical Discharge Machining (EDM)/Electrochemical Machining (ECM) EDM/ECM hybrid process. A hybrid method of EDM-ECM combined processing involve EDM shaping as well as electrochemical machining (ECM) finishing, also, they are conducted in sequence one same machine tool, same electrode, yet on the different dielectric. In this study, the used workpiece material is the A2-Tool Steel material, while the electrode material is copper. The influence of controllable parameters could be identified via response surface methodology (RSM), these controllable effects include: pulse current, pulse on time, pulse off time, gap, voltage, and electrolyte concentration on surface cracks density (SCD). It has been noticed that model has been developed by RSM adequacy is acceptable because the coefficient of determination is closest to one for SCD, whereas the optimal solution achieved by Desirability Function Analysis (DFA) are (current =42 A, pulse-on time =100 , and pulse-off time =50 )in addition to that, the generated surface doesn’t have any crack which has been generated via EDM are removed entirely through ECM finishing. KeywordsHybrid Machining (EDM/ECM), Surface Cracks Density, Response Surface Methodology How to cite this article: S.K. Shather, S.H. Aghdeab and W.S.Khudier, “Enhancement of Surface Crack Density Produce by EDM Using Hybrid Machining,” Engineering and Technology Journal, Vol. 37, Part A, No. 12, pp. 566-573, 2019.
Insights into Conceptus-Reproductive Tract Interactions in the Pig

A better understanding of the mechanisms mediating conceptus-reproductive tract interactions in pigs has important implications for breeding herd productivity and for understanding the effects of selection for reproductive merit on patterns of prenatal loss and associated changes in the uniformity and growth potential of offspring. Nutrition and metabolic state have an important impact on embryonic and fetal development, and there is extensive evidence for both direct and indirect effects of nutrition on the reproductive tract of pigs. Changes in progesterone status can be a key mediator of indirect effects on early embryonic development. Using the cyclic, unilaterally ovariectomized gilt model, we have initially confirmed steroid-dependent changes in the secretion of oviduct proteins (POSP 1-3) as one possible component of this effect. The identification of other genes that are differentially expressed in the oviduct in the peri-implantation period is progressing, using the DD-RT-PCR approach. At the uterine level, the study of the pattern of expression of matrix metalloproteinases (MMP) and their regulators during the periimplantation period has contributed to our understanding of the regulation of the noninvasive type placental development in pigs. A failure of the blastocyst to express MMP-9 may be a key factor and seems to be dependent on local inhibitory regulation within the uterus. The coexpression of MMP-2, tissue inhibitor of MMP-2, and MMP-14 may be linked to the morphological development of the extraembryonic tissues. Changes in plasminogen activator expression are consistent with an estrogenmodulated role in tissue remodeling during embryogenesis. Studies of the integrin family of adhesion molecules also revealed key mediators of the adhesion and attachment process that is fundamental to the development of the diffuse, epitheliochorial placenta of pigs. The lack of the αv subunits on the apical surface of the trophoblast, associated with uterine epithelial expression of both αvβ1 and αvβ3, suggests that attachment is directed from the maternal side. From the perspective of the trophoblast, the low expression of the αvβ1 subunit is consistent with noninvasive placentation. The temporal expression of other integrins is consistent with a role in the migation of both extraembryonic endoderm and mesoderm during embryogenesis.
ANTIOXIDATIVE AND FREE RADICAL SCAVENGING POTENTIALS OF HABENARIA PECTINATA

Objective: This study was designed to evaluate the antioxidative potential of tubers of Habenaria pectinata. Methods: The tubers of H. pectinata were extracted using hexane, ethyl acetate, methanol, and water as solvents. The anti-oxidant potential of extracts was evaluated using free radical scavenging and reducing power assays. The most active methanolic extract was then fractionated into four fractions using the above-mentioned solvents. Results: The phenol and flavonoid content was found to be maximum in the methanol extracts. All the extracts and fractions showed significant levels of antioxidant activity except hexane extract. Conclusion: The tubers of H. pectinata were found to possess a significant antioxidant potential and can be explored further for isolation and preclinical investigation for the ailment of various diseased states and disorders.
Voie d'immunisation et séquence d'administration de l'antigène et de l'adjuvant : facteurs critiques pour une réponse lymphocytaire T efficace

CD8+ T cell responses are crucial in the defense against several infectious agents, as well as for the treatment of cancer. Thus, the development of vaccine strategies capable of eliciting robust CD8+ T cell responses is needed. Antigen cross-presentation is known to be an important mechanism for the activation of antigen-specific CD8+ T cells, and multiple parameters contribute to the efficiency of cross-priming. We examined two of them : the route of immunization and the timing of adjuvant delivery. First, we developed the tetramer-based enrichment strategy, which allowed us to study the endogenous CD8+ T cell response. Then, we investigated the impact of the route of immunization on CD8+ T cell cross-priming. We report that local delivery of cell-associated antigen results in delayed cross-priming due to the increased time required for antigen capture and presentation. In comparison, delivery of systemically disseminated antigen resulted in rapid T cell priming. Surprisingly, local injection of cell-associated antigen, while slower to mount a functional response, resulted in the differentiation of a more robust effector T cell population. We were next interested in evaluating the combination of cell-associated antigen with the delivery of poly I:C, an adjuvant known to induce the production of type I interferons (IFN). We observed an immunization-route-specific effect regarding the timing of innate immune stimulation and identified the optimal time window for adjuvant administration in order to maximize the boosting effects on CD8+ T cell cross-priming. We characterized in detail several effects of poly I:C, as well as type I IFN, exerted on immune cells
EXTRACTION AND ACID HYDROLYSES OF FRESH JERUSALEM ARTICHOKE INULIN FOR FRUCTOOLIGOSACCHARIDE PRODUCTION

The objective of this study was to produce fructooligosaccharide (FOS) from fresh jerusalem artichoke (JAT) inulin which was extracted by conventional method (hot water extraction) at two different temperature (80 ̊C & 90 ̊C\ 90 min). JAT slices were mixed with distilled water at (1 : 5) (w : v) ratio, the obtained extract purified and concentrated to 32 ̊Brix, then mixed with acetone (1 : 3) (v : v), kept at 4 ̊C for 24 h. , centrifuged at 10000g/ 15 min., and the precipitate dried at 55 ̊C. Acid hydrolysis of the dried inulin was carried out at three different pH values being (1.5, 2.5 & 3.0) at 85 ̊C using citric acid (10 %), aliquot of inulin hydrolysate were taken after (5, 10, 15, 20, 25 & 30) min. for qualitative analysis using TLC and RP-HPLC. The results revealed that there were no significant differences in the yield of extracted inulin (33.86, 33.67 %) and extraction efficiency (80.62, 80.17 %) between the extraction at 80 ̊C and 90 ̊C\ 90 min. respectively. The optimum condition for acid hydrolysis of the obtained inulin was at pH 2.5 after 15 min at 85 ̊C. The qualitative analysis for hydrolysate using TLC and RPHPLC showed that the degree of polymerization (DP) of inulin ranged from (2 35) unit and for FOS ranged
Molecular Characterization of Potent Biocontrol Isolates of Trichoderma asperellum and Pseudomonas fluorescens from Tomato Rhizosphere

ISSN: 2319-7706 Volume 9 Number 1 (2020) Journal homepage: http://www.ijcmas. com The potent native bioagents isolated from tomato rhizosphere have high antagonistic potential against Phytophthora infestans. Molecular characterization of fungal isolates (T-11 and T-14) was performed by using Internal Transcribed Spacer (ITS) region of 18S rRNA sequence. The sequence analyses of two isolates (MK928414 and MK928417), showed 100% similarity with Trichoderma asperellum during BLAST analysis. The phylogeny tree constructed by using sequence analysis showed the formation of cluster along with T. asperellum and both the isolates were identified as T. asperellum. The rhizospheric potential bacterial isolates (Pf-2 and Pf-3) were isolated and characterized at molecular level. Bacterial isolates were identified as Pseudomonas fluorescens by using 16S-23S rRNA intervening sequence specific ITS1 and ITS2 primers. The sequence analyses of two isolates showed 89.76-92.67% similarity with P. fluorescens during BLAST analysis and received the NCBI GenBank accession number of MN783298 and MN783297 for Pf-2 and Pf-3 isolates respectively. These isolates were further confirmed by phenotypic characteristics. It is inferred from the present study, that taxonomical knowledge on bioagents is important for accurate identification and molecular characterization of potential biocontrol species. This is to undeniably avoid potential risk of introducing an unknown bacterial and fungal species into the rhizosphere of a given ecosystem. K e y w o r d s Tomato; Trichoderma; Pseudomonas; ITS region; Phylogenetic analysis Accepted: 15 December 2019