Miracle-dz/UniFAR-FTUs huggingface dataset:
Clustering analysis: A case study of the environmental data of RAMA-Toluca

Recently, the climatic analysis has been widely studied with artificial intelligence tools. The importance of this topic is based on the environment impact produced for natural variations of the data on a certain ecosystem. In this paper, a first study of meteorological parameters obtained with the Automatic Network of Atmospheric Monitoring (by its abbreviation in Spanish, RAMA) of the Toluca, Mexico, is exposed. The period studied includes from 2001 to 2008 year. The RAMA-Toluca includes seven monitoring stations located in the Toluca Valley. Using clustering algorithms, the experimental results establish the base for determinate the days distribution in clusters, which could be oriented to the natural cluster that the days have in climatic seasons. However, the results show a different situation than the awaited one. With this, the bases for future work in the climatic analysis context in the Toluca Valley. Key words: Clustering analysis, environmental data, RAMA-Toluca, days distribution
A naturalistic comparison study of effectiveness of intramuscular olanzapine and intramuscular haloperidol in acute agitated patients with schizophrenia

Objective This study was a comparative investigation of the clinical effectiveness of intramuscular (IM) olanzapine, and IM haloperidol in acute agitated patients with schizophrenia. Methods The subjects were 58 schizophrenic patients with psychomotor agitation (moderate and severe) in the emergency ward of a psychiatric hospital. Their clinical symptoms were assessed using Positive and Negative Syndrome Scale Excited Component (PANSS-EC), and anti-agitation treatments with antipsychotics were evaluate at the beginning of treatment, and at 30, 60, 90 and 120 minutes. This was done using the Positive and Negative Syndrome Scale Excited Component (PANSS-EC). Results The mean of clinical symptoms from baseline on the PANSS-EC, were different in the groups IM olanzapine 10mg and IM haloperidol (5mg and 10 mg). Statistically significant differences of PANSS-EC scores were found for moderate and severe psychomotor agitation, when comparing times of study for each treatment group. Conclusions The results of this study suggest the possibility that the anti-agitation effects of IM haloperidol (10 mg) are more rapid than those of IM haloperidol 5mg and IM olanzapine 10 mg. No extrapyramidal symptoms (EPS) were observed.
Tetherless mobile micrograsping using a magnetic elastic composite material

In this letter, we propose and characterize a new type of tetherless mobile microgripper for micrograsping that is made of a magnetic elastic composite material. Its magnetically-programmable material and structures make it the first three-dimensional (3D) mobile microgripper that is directly actuated and controlled by magnetic forces and torques. With a symmetric four-limb structure, the microgripper is 3.5 mm long from tip to tip when it is open and 30 μm thick. It forms an approximate 700 μm cube when it is closed. The orientation and 3D shape of the microgripper are determined by the direction and strength of the applied magnetic field, respectively. As a mobile device, the microgripper can be moved through aqueous environments for precise grasping and transportation of micro-objects, pulled by magnetic gradients directly or rolled in rotating magnetic fields. The deformation of the microgripper under magnetic actuation is characterized by modeling and confirmed experimentally. Being directly controlled by magnetic forces and torques, the microgripper is easier and more intuitive to control than other magnetic microgrippers that require other inputs such as thermal and chemical responses. In addition, the microgripper is capable of performing fast repeatable grasping motions, requiring no more than 25 ms to change from fully open to fully closed in water at room temperature. As a result of its large-amplitude 3D deformation, the microgripper can accommodate cargoes with a wide range of geometries and dimensions. A pick-and-place experiment demonstrates the efficacy of the microgripper and its potentials in biomedical, microfluidic, and microrobotic applications.
Amelioration of Diazepam Induced Memory Impairment by Fruit of Cucumis sativus L . in Aged Mice by Using Animal Models of Alzheimer ’ s Disease *

Traditionally fruit of Cucumis sativus var sativus L. (Cucurbitaceae) has been used for its high fiber and vitamin content in gastrointestinal, skin problems and as cooling agent for body as well as brain. The present study assessed the pharmacological effects of cucumber on learning and memory capabilities of mice. Fresh cucumber paste in doses 3, 6, 9 g/kg were fed orally to mice for 15 successive days. Elevated plus maze, sodium nitrite induced metabolic hypoxia and object recognition task models were employed to test learning and memory. Biochemical tests measured anti-cholinesterase activity in brain, serum glucose levels, cholesterol levels, malonadialdehyde levels and reduced glutathione levels in the brain of mice. 9 and 6 g/kg doses reduced TL of mice significantly on 14 (P < .05) as well as 15 day (P < .001 and P < .01 respectively) in EPM whereas in diazepam induced amnesia 6 mg/kg dose reduced transfer latency significantly (14 day P < .01 and 15 day P < .001). 6 mg/kg dose increased FESC, NESC and DESC in small compartment scores profoundly (P < .05) in sodium nitrite induced hypoxia model and depicted significantly (P < .001) enhanced d2 index in object recognition task. Brain AChE and serum cholesterol levels were reduced significantly (P < .01) by 9 g/kg dose whereas the lower dose (6 g/kg) dose depicted significant (P < .01) results on blood glucose, brain GSH and lipid peroxide levels. This is the first report describing that cucumber increased learning and memory in rodents. Various chemical constituents such as agmatine, cucurbitacins, vitamins etc make the cucumber a deserving candidate for studying its effects on brain. Further research is needed for elucidation of its mechanism in brain and specific chemical constituent responsible for its memory modulating activity in aged mice.
R&D, Spillovers, Innovation Systems and the Genesis of Regional Growth in Europe. Bruges European Economic Research (BEER) Papers 5/October 2006

Research on the impact of innovation on regional economic performance in Europe has fundamentally followed three approaches: a) the analysis of the link between investment in RD b) the study of the existence and efficiency of regional innovation systems; and c) the examination of geographical diffusion of regional knowledge spillovers. These complementary approaches have, however, rarely been combined. Important operational and methodological barriers have thwarted any potential cross-fertilization. In this paper, we try to fill this gap in the literature by combining in one model R&D, spillovers, and innovation systems approaches. A multiple regression analysis is conducted for all regions of the EU-25, including measures of R&D investment, proxies for regional innovation systems, and knowledge and socio-economic spillovers. This approach allows us to discriminate between the influence of internal factors and external knowledge and institutional flows on regional economic growth. The empirical results highlight how the interaction between local and external research with local and external socioeconomic and institutional conditions determines the potential of every region in order to maximise its innovation capacity. They also indicate the importance of proximity for the transmission of economically productive knowledge, as spillovers show strong distance decay effects. In the EU-25 context, only the innovative efforts pursued within a 180 minute travel radius have a positive and significant impact on regional growth performance.
Molecular Detection of Beta-Lactam Resistance Genes in Staphylococcus Aureus Isolated From Women in Nasarawa State, Nigeria

Resistance to antimicrobials by pathogenic microorganisms has raised serious global clinical concerns in recent times. The present study aimed at detection of ? -lactam resistance genes in S. aureus isolates from women with symptomatic and asymptomatic cases of urinary tract infections in Nasarawa state, Nigeria. A total of 200 non-repetitive midstream urinal samples were analysed and 50 (29%) bacterial isolates were identified as S. aureus. The susceptibility profile of the bacterial isolates to tested antibiotics was Nitrofurantoin (74.1%), Gentamicin (72.4%), Ciprofloxacin (65.5%), Ofloxacin (56.9), Augmentin (36.2%), Cotrimozazole (29.3%), Ampicillin (27.6%), Erythromycin (25.8%), Ceftazidine (20.7%) and Cefurozime (10.3%). Thirteen bacterial isolates were found to be resistant to all ? -lactam antibiotics tested, out of which 7 were confirmed ? -lactamase producers using the acidometric and iodometric methods. The detection of ? -lactamase genes (blaZ, blaI and blaR1) was carried out and only five of the isolates were found to be expressing the blaI genes. This research finding suggests that ? -lactam resistance by S. aureus may not be dependent only on the blaZ, blaI and blaR1 genes.
Some methodological aspects for measuring asynchrony detection in audio-visual stimuli

For audio-visual stimuli with a clear temporal structure, like impact events, a difference exists between physical and perceived synchrony. We compare the results of different methods to establish the point of subjective equality (PSE). These methods differ in the type of response categories subjects can use: 1) 3 categories: audio first, synchronous, video first, 2) 2 categories: synchronous, asynchronous, 3) 2 categories: audio first, video first. It appears that the estimates of the PSE obtained with methods 1 and 2 are rather robust and in agreement with each other. In contrast, method 3 allows for different decision strategies and results depend on which strategy the subject chooses.
Fluctuations of Stiff Polymers and Cell Mechanics

Understanding complex systems through the study of minimal models that capture their underlying universal principles has always been the tradition of physics. This reductionist approach is challenged by the vast complexity of life and the accumulating knowledge in molecular biology. Biological sciences have always laid an emphasis on diversity rather than on simplicity and universality. And rightly so, since diversity is a sine qua non of evolutionary robustness and adaptability (Kirschner & Gerhart, 1998). Bearing in mind this tension, the insight that cellular functions can be attributed to functional modules (Hartwell et al., 1999) as a higher level of biological organization offers a new perspective on a possible unification of the two seemingly contradictory paradigms. It stimulated the emergence of “bottom-up approaches” (Bausch & Kroy, 2006; Schwille & Diez, 2009; Liu & Fletcher, 2009) aiming at the reconstitution of functional modules of cell biology in-vitro. The reconstitution of a simplified biological system with a reduced number of components mutually depends on a detailed level of physical understanding, reveals how evolved biological systems work and provides insight into how new biological functions could be engineered. Cellular mechanics represents an important example for the application of this idea (Bao & Suresh, 2003; Discher et al., 2009; Fletcher & Mullins, 2010). The bottom-up approach to cell mechanics has revealed the basic mechanisms underlying the complex mechanical behavior of the eukaryotic cytoskeleton (Fig. 1, left) by reconstituting self-assembling networks of biopolymers in-vitro in an attempt to balance the mutually conflicting demands for simplicity and complexity (Fig. 1, middle) (Bausch & Kroy, 2006). The present contribution adopts the coarse-graining approach tested in polymer physics and explores how far it takes us in the task of understanding the functional modules responsible for cellular mechanics. We progress from a minimal model for single semiflexible polymers to a theoretical description of their complex networks. It turns out that on this basis many crucial features found in experimental studies of cellular mechanics can be understood qualitatively if not quantitatively. Semiflexible polymers are characterized by their persistence length lp, which is a mesoscopic length scale, much larger than the microscopic
Values, Beliefs and Norms that Foster Chilean and German Pupils' Commitment to Protect Biodiversity.

Fostering young people‟s commitment to protect biodiversity is an important goal of Education for Sustainable Development (ESD) in both, industrial countries and designated biodiversity hotspots. However, little empirical evidence exists to describe factors that influence such commitments. Based on the Value-Belief-Norm (VBN) theory, 15 to 19-year-old Chilean (n= 216) and German (n= 217) pupils‟ commitment to protect biodiversity was investigated. Comparisons revealed that Chilean adolescents showed higher personal norms and commitments to protect biodiversity. Regression analysis showed that within the German sample, the „Schwartz‟-value universalism was an important predictor for three different kinds of behavioural commitment. In both samples, „ascription of responsibility‟, „perceived ability to reduce threat‟ and, above all, „personal norms‟ were positive predictors. The paper concludes with a discussion of the results in the light of existing evidence and suggests implications for biodiversity education.
Factors Influencing The Adoption Of Social Media In Small And Medium Enterprises (SMES)

Small and Medium Enterprises (SMEs) industry has developed rapidly and it has become one of the major contributors to the Malaysian economy. This research is focused on the food and beverage industry at Halal SMEs which were developed to become export-ready so that they will gradually become a global player. Social media can be described as a newly emerging phenomenon in which it has evolved the business operating environment in Malaysia. Additionally, social media allows businesses to communicate speedily and cheaply with customers. It is also a medium to build a strong customer and public relationship, market development and to gain information that can be used to generate business leads that may increase sales and thus grows the Halal SMEs. This research will also focus on the factors influencing the adoption of social media in Halal SMEs. The social media adoption models were developed from the theory of Technology Acceptance Model (TAM) by including the perceived usefulness, perceived ease of use and perceived trust. The survey method was chosen in order to prove the factors influencing the adoption of social media among Halal SMEs. The result showed that all the three variables (perceived usefulness, perceived ease of use and perceived trust) in this study have their relationship with the dependent variables (adoption of social media). From the regression analysis result, perceived usefulness is the highest factor that influences the adoption of social media in food and beverage industry at Halal SMEs.
Effector Response of the Aspartate Transcarbamoylase From Wild Type Pseudomonas Putida and a Mutant with 11 Amino Acids Deleted at the N-terminus of PyrB.

Like its enteric counterpart, aspartate transcarbamoylase (ATCase) from Pseudomonas putida is a dodecamer of two different polypeptides. Unlike the enterics, the Pseudomonas ATCase lacks regulatory polypeptides but employs instead inactive dihydroorotases for an active dodecamer. Previous work showed that PyrB contains not only the active site but also the effector binding sites for ATP, UTP and CTP at its N-terminus. In this work, 11 amino acids were deleted from the N-terminus of PyrB and the ATCase with the truncated protein was expressed in E. coli pyrB- and purified. The wild type enzyme was similarly treated. Velocity-substrate plots without effectors gave Michaelis-Menten kinetics in all cases. Deleting 11 amino acids did not affect dodecameric assembly but altered effector responses. When carbamoylphosphate was varied, the mutant enzyme was inhibited by UTP while the wild type enzyme was activated 2-fold. When the aspartate was varied, CTP had no effect on the mutant enzyme but strongly inhibited the wild type enzyme.
Human Torso Pose Forecasting in the Real World

In this paper, we describe a multi-modal approach to human torso pose estimation and forecasting. Our end-to-end system combines RGB images and point cloud information to reason about 3D human pose. We use a simple filter fit method to forecast torso pose. Further, we evaluate the forecasting performance quantitatively on the Human3.6M motion capture dataset and qualitatively on a furniture assembly task. Our simple forecasting algorithm outperforms complicated recurrent neural network methods, while being faster on the torso pose forecasting task.
Looking for honesty: The primary role of morality (vs. sociability and competence) in information gathering

Research on the two fundamental dimensions of social judgment, namely warmth and competence, has shown that warmth has a primary and a dominant role in information gathering about others. In two studies we examined whether the sociability and morality components of warmth play distinct roles in such a process. Study 1 (N = 60) investigated which traits were mostly selected when forming impressions about others. The results showed that, regardless of the task goal, traits related to morality and sociability were differently processed. Furthermore, participants were more interested in obtaining information about morality than about sociability when asked to form a global impression about others. Study 2 (N = 98) explored the adoption of asymmetric/symmetric strategies when asking questions to make inferences on others. As predicted, participants adopted an asymmetrically disconfirming strategy on morality traits, while they looked for more symmetrical evidence on sociability or competence traits. Overall, our findings indicated a distinct and a dominant role of the moral component of warmth in the information-gathering process. Copyright © 2010 John Wiley & Sons, Ltd.
ASSOCIATION BETWEEN SLEEP DISORDERS AND CHRONIC DISEASES IN PATIENTS OF THE BRAZILIAN NATIONAL HEALTH SYSTEM ASSOCIAÇÃO ENTRE DISTÚRBIOS DO SONO E DOENÇAS CRÔNICAS EM PACIENTES DO SISTEMA ÚNICO DE SAÚDE

RESUMO Inúmeros fatores estão associados aos distúrbios do sono ocasionando o aumento nos gastos com saúde. O objetivo do trabalho foi analisar a associação dos distúrbios do sono e doenças crônicas não transmissíveis em pacientes com idade superior a 50 anos atendidos por Unidades Básicas de Saúde de Presidente Prudente. Participaram 363 pacientes. O histórico de doenças foi auto relatada a partir da aplicação de questionário, o nível de atividade física foi verificado através do questionário de Baecke, e a qualidade do sono foi avaliada utilizando o Mini-Sleep questionnaire. Dados antropométricos e de composição corporal foram coletados utilizando estadiômetro e balança, foram considerados obesos os pacientes dentro do percentil 75. A análise estatística foi composta pelos testes t de Student, qui-quadrado, e regressão logística binária. Os resultados mostraram que o distúrbio do sono está associado as doenças osteoporose, artrite/artrose, dor lombar, depressão e obesidade. Adicionalmente obesidade e inatividade física influenciam na ocorrência de doenças crônicas não transmissíveis. Palavras-chave: Distúrbio do sono. Doenças crônicas. Sistema único de saúde. ABSTRACT Many factors are associated with sleep disorders, causing an increase in health spending. The objective of this study was to analyze the association of sleep disorders and non-communicablechronic diseases in patients over 50 years of age, attended by Basic Health Care Units of Presidente Prudente. In total, 363 patients participated. The history of diseases was selfreported through the use of a questionnaire, the level of physical activity was evaluated by the Baecke questionnaire, and sleep quality was assessed using the Mini-Sleep Questionnaire. Anthropometric and body composition data were collected using a stadiometer and scale; patients in the highest (75) percentile were considered obese. Statistical analysis was performed using the Student t test, chi-square test, and binary logistic regression. The results showed that sleep disorders are associated with osteoporosis, arthritis/osteoarthritis, low back pain, depression, and obesity. Additionally, obesity and physical inactivity influence the occurrence of non-communicable chronic diseases.
Association of PTPRD Gene Polymorphism and Non-small Cell Lung Cancer Risk

Background: Non-small-cell lung cancer (NSCLC) is one of the leading causes of cancer death worldwide. Genetic variations may play a role in NSCLC progression and prognosis. Objective: This study investigated protein tyrosine phosphatase receptor delta (PTPRD) rs2279776 with NSCLC susceptibility, chemotherapy response and survival in a Chinese population. Methods: A total of 352 cases and 704 controls were enrolled. Logistic regressions were used to evaluate the associations of genetic polymorphism with NSCLC risk and chemotherapy response. Overall survival was analyzed using the Kaplan-Meier method and the survival curves were compared with log-rank test. Subgroup analyses were also performed. Results: PTPRD rs2279776 was significantly associated with NSCLC risk. Under the dominant model, rs2279776 minor allele carriers (GC+CC) had a significantly increased risk of NSCLC compared to major allele homozygotes (GG) (P=0.01, odds ratio=1.38, 95% confidence interval=1.07-1.79). The association remained significant after adjustment of covariates, and also in males and age >60 years subgroups. No association was observed between this polymorphism and chemotherapy response in advanced NSCLC patients. Survival analyses could not detect any effect of rs2279776 on NSCLC survival. Conclusions: Genetic polymorphism of PTPRD gene could be
Mathematical Tasks and the Student

Mathematics Education has at its core a conception of the mathematical performances that represent the aspirations of the mathematics classroom and curriculum. These performances are constituted through teacher and student participation in the activities stimulated by mathematical tasks selected by the teacher for the realization of an instructional purpose. In this nexus of activity, intention, interpretation and consequence, the mathematical task occupies a central place. This Research Forum provides an opportunity to explore and reflect upon the role that mathematical tasks play in the achievement of the goals of the international mathematics education community. Further, consistent with current curricular and theoretical priorities, the agency, attributes and activities of the student are foregrounded in the discussion of the instructional use of mathematical tasks. The contributors to this Research Forum represent a wide variety of theoretical perspectives and report research undertaken in different school systems and different cultures. These different perspectives offer a useful exploration of the theme: Mathematical Tasks and the Student.