Miracle-dz/UniFAR-FTUs huggingface dataset:
Impact of diabetes on gastrointestinal and urinary toxicity after radiotherapy for gynecologic malignancy

Objective: Although diabetes is a common co-morbidity in patients with gynecologic cancer, information about its impact on radiation toxicity in patients with gynecologic cancer treated with external pelvic irradiation is scarce. We aimed to investigate the relation of diabetes with acute toxicity in patients with gynecologic tumors who underwent pelvic +/- paraaortic radiotherapy. Materials and Methods: One hundred twenty-nine patients with endometrium or cervix carcinoma were enrolled in the study. Demographic features, presence of diabetes, incidence and severity of upper gastrointestinal (UGIS), lower gastrointestinal (LGIS), and urinary symptoms were recorded from files. Correlation and logistic regression analysis was used to determine the impact of diabetes, age, chemotherapy, paraaortic irradiation on toxicities, and a prediction model was developed. Results: The median age of 77 patients with endometrium cancer and 52 cervix cancer was 61 (range, 25-92) years, and 28 (21.7%) of them had diabetes. The median pelvic and tumor/tumor bed dose was 5040+247.65 cGy and 5040+222.91 cGy, respectively. Age and Gr 0 UGIS toxicity were significantly related (p=0.047). LGIS Gr 0 toxicity was found to be significantly higher in patients with diabetes (p=0.045). Gr 0 and 2 UGIS toxicities were both found to be significantly correlated with paraaortic irradiation (both p<0.001). Diabetes is also an important determinant on UGIS toxicity in patients who underwent paraaortic irradiation. Conclusion: The correlation we found between toxicity and diabetes, concurrent chemotherapy or paraaortic radiation necessitates special care and risk stratification for patients with diabetes. Further prospective studies with long follow-up and larger patient groups are warranted.
Detection of HSV and CMV in Pregnant and Miscarriage women by ELISA and real time PCR Assay

Herpes Simplex Viruses (HSV) and Human Cytomegaloviruses (HCMV) are the major cause of serious viral complications in pregnant women. Screening methods that is ELISA for detecting Herpes Simplex virus(HSV) and Human Cytomegalovirus(HCMV) tend to be slow and insensitive. Therefore in this work, a rapid Real Time PCR (qT-PCR) and ELISA based assay was designed to detect HSV and CMV among pregnant women in Iraq from serum samples. Our study revealed that among the ELISA screened 420 sera samples, 81 (19.3%) of CMV and 17(4.05 %) of HSV were positive, while 64 (12.9%) had positive results for CMV DNA and 5(1.2%) had HSV DNA through real-time PCR. Real time PCR was more sensitive and reliable method in diagnosis of CMV and HSV infections in pregnant women in this comparative study.
Changes in Selected Blood Minerals, Vitamins and Thyroid Hormones in Barky Ewes during Late Pregnancy, Post-Partum and Early Lactation

Changes in Selected Blood Minerals, Vitamins and Thyroid Hormones in Barky Ewes during Late Pregnancy, Post-Partum and Early Lactation N. F. KHALED1* J. ILLEK2 1 Department of Nutrition & Clinical Nutrition, Faculty of Veterinary Medicine, Cairo university 1221 Giza, EGYPT 2 Department of Ruminant Diseases, Faculty of Veterinary Medicine, University of Veterinary and Pharmaceutical Science, Brno,
AMELIORATION OF CARRAGEENAN-INDUCED INFLAMMATION AND HYPOTHYROIDISM BY ETORICOXIB, A COX-2 INHIBITOR, IN RAT MODEL

The present study was premeditated to reveal the amelioration of carrageenan-induced inflammation and hypothyroidism by Etoricoxib, a selective COX-2 inhibitor, in Wistar rat model. Carrageenan was administered to induce paw edema and alteration in thyroid functions, glucose metabolism; lipid peroxidation (LPO) in hepatic; renal and cardiac tissues along with serum total cholesterol (TC) and highdensity lipoprotein cholesterol (HDL-C) levels in female Wistar rats were studied. Besides tissue glutathione content, alteration in body weight along with daily rate of food and water intake was also analyzed. Carrageenan administration on the hind footpad of rats significantly increased paw volume, tissue LPO, serum insulin, glucose and TG levels; it lowered circulating HDL-C level with a marked decline in the serum levels of T3 and T4 and daily rate of food and water consumption. While etoricoxib administration along with carrageenan treatment; status of all the thyroid dependent parameters was reversed with a consistent increase in circulating thyroid hormone levels. The findings of present study are suggestive that the drug might be acting through the restoration of thyroid homeostasis which in turn ameliorates inflammation and oxidative stress.
Nephrologist and Intensive Care Unit

Background. Collaboration between the nephrologist and the intensivist has been the most urgent and necessary in the diagnosis, optimal therapy and in establishing of 21 patients with acute renal failure of traumatic origin, 50 patients after acute intoxication by organophosphate inhibitors of cholinesterases, and 20 patients after acute ethylene glycol poisoning received treatment at the department of anaesthesiology and intensive medicine, intensive care unit of the IVth Medical Clinic, or the Nephrological Clinic of the Faculty Hospital of L. Pasteur in Kooice, Slovak Republic. Methods. In addition to conservative therapy all basic forms of extracorporeal elimination therapy (acetate, and later exclusively bicarbonate haemodialysis, haemoperfusion using charcoal and other sorbents) were used. Results. Out of 91 patients, 14/21 died from the first group, 4/50 died in the second group, and 3/20 patients died after ethylene glycol intoxication. Conclusions. The nephrologist was the chief consultant in establishing the diagnosis and treatment of acute renal failure and managing acute intoxication to avoid delay in the use of an early, adequate conservative and extracorporeal elimination therapy.
Outcome of total Achilles tendon rupture repair, with special reference to suture materials and postoperative treatment

The purposes of the present research were to compare the outcome after Achilles tendon rupture repair in two postoperative regimens, to compare Achilles tendon elongation in two postoperative treatment methods, to compare the effects of two postoperative methods on motor performance aspects such as simple reaction time, choice reaction time, speed of movement, foot tapping speed and coordination, to test the mechanical properties of the recently developed poly-L/D-lactide (PLDLA) sutures and Maxon® sutures when implanted in the Achilles tendons of rabbits, and to study the histological tissue reactions and biodegradation of these sutures under the same conditions. Isokinetic calf muscle strength scores at the last control check-up were excellent in 56% of the patients in the early motion group, good in 32%, fair in 8%, and poor in 4%, whereas the scores in the cast group were excellent in 29% of cases, good in 50% and fair in 21%. The ankle performance scores were excellent or good in 88% of the patients in the early motion group, fair in 4% and poor in 8%, whereas the scores in the cast group were excellent or good in 92% of cases and fair in 8%. No significant differences were seen between the two groups at 3 months and at the last control checkups with regard to pain, stiffness, subjective calf muscle weakness, footwear restrictions, range of ankle motion, isokinetic calf muscle strength or overall outcome. The complications included 1 rerupture in the early motion group and 1 deep infection and 2 re-ruptures in the cast group. AT elongation occurred in both groups, but was somewhat less marked in the early motion group. The AT elongation curves rose at first and then fell slowly in both groups. The patients who had less AT elongation achieved a better clinical outcome. AT elongation did not correlate significantly with age, body mass index or isokinetic peak torques. The recovery of motor performance functions such as simple reaction time, choice reaction time, speed of movement, foot tapping speed and coordination did not depend on the two postoperative regimens. The motor functions of the operated leg had obviously recovered to the level of the nonoperated leg 12 weeks after the operation. Sutures made of PLDLA were used successfully for Achilles tendon repair in rabbits. There was no significant difference between the in vitro and in vivo tensile strength retention of the sutures. By comparison with Maxon®, PLDLA was found to have a lower initial tensile strength but more prolonged strength retention. The breaking strength values of the Achilles tendons repaired with sutures of these types were not significantly different at 6 weeks. Intratendinous PLDLA sutures formed a thinner fibrous capsule during the 12-week follow-up period than did Maxon® sutures of the same diameter. The suture materials had not been totally absorbed by 12 weeks.
NF-κB – a target in the inflammation of bone destruction

NF-κB activation is associatied with the inflammation of bone destruction and certain cancers. The NEMO (NF-kB essential modulator)-binding domain (NBD) protein inhibits the activation of NF-κB. Cellular studies have shown that the NBD protein inhibits osteoclastogenesis. Mimicking infection with a lipopolysaccharide injection in mice resulted in activated osteoclasts and reduced bone mineral density. These responses are inhibited with the NBD peptide. In a mouse model of rheumatoid arthritis, collagen-induced arthritis, treatment with the NBD protein delayed the onset, lowered the incidence and decreased the severity of the arthritis. NF-κB is a target in the inflammation associated with bone destruction. A key issue is whether or not this important transcription factor can be inhibited without causing excessive adverse effects and/or toxicity.
Sugar or salt: the use of 5% dextrose in the adult, non-diabetic haemodialysis population

Results: Analysis of the data showed no difference in the interdialytic weight gain from baseline to week 11. However, from week 12 to week 20 interdialytic weight gain was found to be significantly reduced. Cramping during dialysis decreased from baseline and week 12 compared to subsequent weeks; however, this was not statistically significant (p=0.07). The pre-dialysis blood pressure was found to be elevated in participants following conversion.
THE NURSES’ MOTIVATING FACTORS IN RELATION TO PATIENT TRAINING

:لوؤـــــسم هدنـــسیون هدکشناد ؛یعولط مرتحم ییاــــ مام و یراتــسرپ یکـشزپ موــ لع هاگشناد نارهت e-mail: mtoloei@sina.tums. ac.ir هدیکچ ریثأـت تـحت هــ ک تسا اهتبقارم هیارا رد ناراتسرپ مهم یاهشقن زا یکی رامیب هب شزومآ :فده و هنیمز هـب شزوـمآ اـب طاـبترا رد ناراتـسرپ یــشزیگنا لماوع نییعت فده اب یسررب نیا . دراد رارق نانآ هزیگنا . تسا هدش ماجنا نارامیب اـب طاـبترا رد ناراتـسرپ یــ شزیگنا لماوع نییعت فده اب یفیصوت یعطقم رضاح هعلاطم :یسررب شور 214 هــ علاطم نیا رد . تسا هدش ماجنا نارهت یکشزپ مولع هاگشناد یاهناتسرامیب رد نارامیب هب شزومآ دوخ هویش هب و همانشسرپ زا هدافتسا اب و دندش باختنا یاهشوخ و یاهقبط یریگهنومن شور اب راتسرپ ،رـشیف ،یاــک روذجم نومزآ و یفیصوت رامآ یاهشور زا هدافتسا اب . دش یروآعمج اههداد یهدشرازگ . دش ماجنا لیلحت و هیزجت SPSS رازفامرن و ولراک تنوم زا دنداد ناشن ترکیل سایقم اب مک و طسوتم ،دایز حطس هس رد یشزیگنا لماوع دروم رد اههداد :اههتفای ،(%81/5) راـک هـب هـقلاع ،(%85/5) یهاـگآ ،(%90) یراک نادجو ،(%68) یلغش تینما لماوع ناراتسرپ رظن داـجیا راـمیب هــ ب شزومآ هزیگنا دایز حطس رد (%74) یلغش یاقترا و تفرشیپ ،(%76) ینادردق و تخانش رد (%49/5) تاـناکما ،(%48) دزمتــ سد و قوقح ،(%57/5) یتسرپرس و تراظن لماوع هک یلاح رد . دننکیم لـماوع اـب یدرـف یاـهریغتم زا یـخرب نـینچمه . دـننکیم داـجیا راـمیب هــ ب شزومآ هزیگنا طسوتم حطس . دنتشاد رادانعم هطبار یشزیگنا و تخانش ،راک هب هقلاع ،یهاگآ ،یراک نادجو ریظن یلماوع هعلاطم زا لصاح جیاتن ساسا رب :یریگهجیتن ریثأــ ت رامیب هب شزومآ ماجنا یارب ناراتسرپ هزیگنا رد یلغش تینما و یلغش یاقترا و تفرشیپ ،ینادردق . دراد یدایز
The Normal Fetal Kidney Measurement in in Normal Pregnant Ladies

Accurate estimation of normal antenatal fetal kidneys size is of great importance, thus determination of normal meas urements was help in early diagnosis and optimize fetal safety then reduce the high prenatal morbidity and mortality. The objectives of this study are: to rule out the normal fetal kidneys dimensions among Sudanese population and to develop a local standar d with ultrasound as well as to detect the range of fetal kidneys size in third trimester among Sudanese population and comparing the results with the international standard. This study was carried out in Khartoum state Sudan at Al Ahfad center for familly health, AAU Radiobiology department, and Alsalam AL Raed hospital from 1 - 8 - 2012 until 1 - 11 - 2012, a total of 100 normal pregnant ladies with no previous delivery of fetus with congenital anomaly or obvious fetal disease at (28 - 40) weeks gestational age. Th e study demonstrated that the mean renal length of fetal kidneys in third trimester in Sudanese was 34.2 mm, 40.9 mm and 44 mm in premature, mature and full - term fetuses respectively. The mean renal width of fetal kidneys in third trimester was 18 mm , 23 mm , and 25.5 mm in premature, mature and full - term fetuses respectively. The mean renal thickness of fetal kidneys in third trimester in was 17.6 mm, 22.2 mm, and 24.5 mm in premature, mature and full - term fetuses respectively. The mean renal volume of fetal kidneys in third trimester was 5.6 mm 3 , 9.8 mm 3 ,and 10.5 mm 3 , in premature, mature and full - term fetuses respectively. The study showed proportional relationship between gestational age and fetal weight. Concerning to the sex there was weak correlation. Comparing the international records the result of the study is more like the Netherlands population . It is recommended to implement this study in ultrasonography departments locally And to establish further studies using large sample volume taking in conce rn all other factors that affect fetal kidneys size. ( Mohamed Adam, Jumaa Yousif Tamboul , Mohamed Yousef , Abdelmoneim Sulieman . The Normal Fetal Kidney Measurement in Third Trimester in Normal Pregnant Sudanese Ladies . J Am Sci 2013;9( 12 ): 794 - 79 7 ). (ISSN: 1545 - 1003). http://www.jofamericanscience. org . 101
Inter-day reliability leg, knee and ankle stiffness measures during hopping

The purpose of this study was to investigate the inter-day reliability of a common method used to measure and calculate leg, ankle and knee joint musculoskeletal stiffness (KLeg, KAnk, Kknee) during hopping. Limited research exists on the reliability of lower extremity musculoskeletal stiffness measures; therefore the reliability of many common methods employed in research studies on hopping has not been adequately established. Twenty active male participants performed one trial of 15 single and double-legged hops at 2.2Hz and at a self-selected frequency during two sessions, separated by 3-7 days. Excellent reliability was shown for KLeg regardless of whether the pace was controlled or self selected, however KAnk and KKnee exhibited only moderate reliability results.
Trakya Bölgesinde Buğday Üreticilerinin Tohumluk Tercihlerini Etkileyen Faktörlerin Faktör Analizi Yöntemi İle Analizi

Ulkemizde yillarca uygulanan fiyat politikalari ureticileri yuksek verim arayisina iterken, dusuk kaliteli bugday uretimini istemeden de olsa tesvik etmekte ve yuksek kaliteli bugdayin uretiminde istenilen duzeye ulasilamadigi gorulmektedir. Zira yuksek kaliteli sert ya da yari sert bugday cesitlerinin verim duzeyi, dusuk kaliteli yumusak cesitlere gore daha dusuktur. Un sanayicileri bugday piyasasinda cok sayida farkli cesitle karsilasmakta ve dusuk kaliteli bugday bollugu nedeniyle kaliteli un amaciyla olusturulan uretim programlari olumsuz yonde etkilenerek bugday ithalati zorunlu olmaktadir. Un sanayinin yasadigi bu surec temel gida maddesi olan ekmegi ureten firincilari ve nihai tuketicileri de olumsuz olarak etkilemektedir. Ureticilerin tohumluk tercihleri bu durum ile yakindan ilgilidir. Faktor analizinin ana amaci boyut indirgemedir (dimension reduction). Boyut indirgemenin) amaci ise veri setini kuculterek daha kolay aciklanabilir hale getirmektir Bu arastirmanin amaci ureticilerin bugday tohumlugu tercihlerini etkileyen faktorleri belirleyerek ciftci tercihlerini etkileyen faktorleri ‘Faktor Analizi’ yontemi ile analiz etmektir. Boylece cok sayida tercih nedenlerini duzenli bir sekilde ortaya koyarak tarim politikalari belirleyicileri ve uygulayicilarina bir olcude de olsa isik tutacak bilgilere ulasmaktir. Analiz sonucunda elde edilen bes grup, bugday ureticilerinin tohumluk secimine etki eden temel faktorleri gostermekte olup tecrube ve tavsiye, yuksek Kalite ve Fiyat, Iklim Kosullarina Uygunluk ve Destekleme Alimlari olarak isimlendirilmistir.
American Medical Students' Beliefs in the Effectiveness ofAlternative Medicine

Introduction: While the use of complementary and alternative medical therapy (CAM) is common in the U.S., there have been no prior national studies of CAMrelated attitudes of U.S. medical students. Methods: We surveyed the Class of 2003 at freshman orientation, entrance to wards, and senior year in a nationally representative sample of 16 U.S. medical schools. Our primary outcome of interest was students’ Likert-scaled responses to the statement “Alternative medicine can often be as effective as traditional medicine. ” Results: With 4764 responses overall (a response rate of 80.3%), 9% strongly agreed, 45% agreed, 34% neither agreed nor disagreed, 11% disagreed, and 2% strongly disagreed that alternative medicine could be as effective as traditional medicine. Students became modestly more polarized in their beliefs, moving from 37% of students neither agreeing nor disagreeing with the statement at freshman year to 31% at senior year. Several variables including gender, paternal educational level, ethnicity, religion, political self-characterization, intended specialty, and preventionorientation were associated with agreement. Conclusions: U.S. patients commonly use CAM, but newly-minted U.S. physicians’ are often skeptical about its efficacy. This disconnect may make it difficult to integrate patients’ CAM use into clinical decision-making.
The effects of mental health education on reducing stigma and increasing positive attitudes toward seeking therapy

Stigma associated with mental health care is an important factor in people’s decision to seek out and engage in psychotherapy or counseling. Many previous studies have suggested that educating individuals about mental health can be an effective tool in reducing stigma towards seeking mental health services. This thesis attempted to measure the effects of mental health education on students’ endorsements of self stigma and social stigma, as well as attitudes towards counseling, and intentions to seek counseling. Social stigma associated with seeking mental health services is the perception that a person who seeks psychological treatment is undesirable or socially unacceptable. Self stigma is the internalization of social stigma or the belief that if one needs psychological treatment he or she is inferior. Several surveys were used in this study to assess the relationship between social and self stigma to attitudes toward seeking psychological help and intentions to seek counseling. A Pearson Correlation revealed that there was a statistically significant positive relationship between ratings of self stigma and attitudes toward seeking psychological services and between self stigma and intentions to seek counseling. Additionally, analysis revealed a statistically significant positive relationship between social stigma and attitudes toward seeking psychological services and between social stigma and intentions to seek counseling. This study also found that the individuals in
The Feasibility of an 8-week, Home-based Isometric Strength Training Program for Improving Dressage Test Performance in Equestrian Athletes

The aim of this study was to determine the feasibility of an 8-week, home-based isometric strength training program in equestrians. Also, we examined changes in muscular strength, endurance, and riding performance. 18 riders (≥1 year dressage experience, riding ≥1 h/week, otherwise untrained) completed pre-/post-muscular tests and a US Equestrian Federation Training Level Rider Test. A progressive, 3 day/week riding-specific intervention using TheraBands® was implemented. Feasibility was determined as >50% of riders completing ≥18/24 sessions of ≥2 sets/exercise of prescribed volume. Dependent samples t-tests compared pre/post composite muscular strength/endurance, and riding test scores. 55.5% of riders completed ≥75% exercise sessions. Significant improvements were observed for muscular endurance (pre 149.8±82.2, post 209.2±112.2; P=0.003), and for riding test scores (pre 57.8±7.4, post 60.8±5.1; P=0.037). Exploratory analyses revealed a significant correlation between improvements in muscular endurance.
Adenosine deaminase and Guanase deaminase activities in serum of patients with rheumatoid Arthritis

We investigated purin and primidin salvage pathways in rheumatoid arthritis (RA). For the aim, Adenosine deaminase (AD) and Guanosine deaminase (GD) activities in serum of patients with di! erent manifestations of the disease (n=32) were investigated and compared with the control group of healthy individuals (n=52). RA cases were classified with respect to their clinics and treatment. The ADA activities were significantly higher (p<0.01) in patients with RA than in control although GD activity levels were found to be lower (p<0.01). When compared their AD and GD levels amongst the classified RA groups, there was no di! erence in AD levels amongst cases. In conclusion, increased serum AD activities in patients with RA may be dependent on and reflect the increase in phagocytic activity of macrophages and maturation of T-lymphocytes. The results indicated that plasma AD and GA activity can be used for the diagnosis of RA disease to support clinical findings and as an index for disease.
Monetary Policy Rules: from Adam Smith to John Taylor - Taylor Conference 2007 - FRB Dallas

The views expressed herein are those of the authors and not necessarily those of the Federal Reserve Bank of Kansas City or the Federal Reserve System. (1993a) suggested that the federal funds rate (r) should normatively (with qualifications) and could positively (at least in the previous 5 years) be explained by a simple equation: