Miracle-dz/UniFAR-FTUs huggingface dataset:
Towards ice thickness inversion: an evaluation of global DEMs by ICESat-2 in the glacierized Tibetan Plateau

Abstract. Accurate estimates of regional ice thickness, which are generally produced by ice-thickness inversion models, are crucial for assessments of available freshwater resources and sea level rise. Digital elevation model (DEM) derived surface topography of glaciers is a primary data source for such models. However, the scarce in-situ measurements of glacier surface elevation limit the evaluation of DEM uncertainty, and hence its influence on ice-thickness modelling over the glacierized area of the Tibetan Plateau (TP). Here, we examine the performance over the glacierized TP of six widely used and mainly global-scale DEMs: AW3D30 (30 m), SRTM-GL1 (30 m), NASADEM (30 m), TanDEM-X (90 m), SRTM v4.1 (90 m) and MERIT (90 m) by using ICESat-2 laser altimetry data while considering the effects of glacier dynamics, terrain, and DEM misregistration. The results reveal NASADEM as the best performer, with a small mean error (ME) of −1.0 and a root mean squared error (RMSE) of 12.6 m. A systematic vertical offset existed in AW3D30 (−35.3 ME and 34.9 m RMSE), although it had a similar relative accuracy to NASADEM (~ 13 m STD). TanDEM-X also performs well (−0.1 ME and 15.1 m RMSE), but suffers from serious errors and outliers on steep slopes. SRTM-based DEMs (SRTM-GL1, SRTM v4.1, and MERIT) (all ~ 36 m RMSE) had an inferior performance to NASADEM. However, their errors were reduced in the ablation zone when glacier variations were excluded. Errors in the six DEMs increased from the south-facing to the north-facing aspect and become larger with increasing slope. Misregistration of DEMs relative to ICESat-2 footprint in most glacier areas is small (less than one pixel). An intercomparison of four ice-thickness models: GlabTop2, Open Global Glacier Model (OGGM), Huss-Farinotti (HF), Ice Thickness Inversion Based on Velocity (ITIBOV), show that GlabTop2 is sensitive to the accuracy of both elevation and slope, while OGGM and HF are less sensitive to DEM quality, and ITIBOV is the most sensitive to slope accuracy. Considering the inconsistency of DEMs acquisition dates, NASADEM would be a best choice for ice-thickness estimates over the TP, followed by AW3D30, and TanDEM-X (if steep and high elevation terrain can be avoided). Our assessment figures out the performances of mainly global DEMs over the glacierized TP. This study not only avails the glacier thickness estimation with ice thickness inversion models, but also offered references for other cryosphere studies using DEM.
ASSOCIATION BETWEEN OBESITY AND KNEE OSTEOARTHRITIS IN USERS OF BRAZILIAN UNIFIED NATIONAL HEALTH SYSTEM ASSOCIAÇÃO ENTRE OBESIDADE E OSTEOARTRITE DE JOELHOS EM USUÁRIOS DO SISTEMA ÚNICO DE SAÚDE BRASILEIRO

Verify possible associations between obesity and knee OA in users of Brazilian Unified National Health System (Sistema Único de Saúde SUS) of primary care network in Catalão-GO, Brazil. This is an observational study conducted in 2014 and 2015. A total of 81 volunteers from the Basic Attention Network in the city of Catalão, with body mass index (BMI) over 30 kg/m in both sexes, age between 40 and 60 years, and OA on radiological examination of the knee. Obesity was classified according to BMI. The diagnosis of osteoarthritis (OA) was made clinically and by radiography according to Kellgren radiological classification. The level of physical activity was assessed using the Baecke questionnaire and the Gordon Functional Classification. The volunteers underwent an anthropometric evaluation and physical examination with inspection and palpation of the joint and subsequent radiological examination of the knee. The volunteers answered a questionnaire on the level of physical activity and functional classification. Data analysis was performed using Fisher’s exact test or chi-square test was used for comparisons of two proportions. In comparisons of continuous variables, Student’s t-test or the nonparametric Wilcoxon-Mann-Whitney test was used. The level of significance was set to 5%. Practice of regular physical exercise decreases functional impairment in obese individuals with knee OA. The weight variable demonstrated a strong association with the severity of OA and degree of functionality of patients. Obesity and OA durations and lack of patient guidance are variables that may contribute to the progression of knee OA. Although the incidence among men is lower, they are more severely affected and anthropometric evaluation and physical examination are an efficacy implementations for Brazilian users of SUS.
Modern Problems of Children's Play: Cultural-Historical Context

The purpose of this article is to analyze the state of modern research on children’s play, approaches to its study, as well as existing methods of its evaluation. The relevance of the topic is due to the leading role of the play in preschool childhood and the complexity of this phenomenon. Play is actively studied, and play interventions are often used. However, the analysis of the literature shows confusion and uncertainty of terminology due to a large spread of theoretical positions and methodological approaches to the study of play. This creates great difficulties in planning and conducting research, and affects their results. The article deals with the issues of defining and classifying play, understanding its structure and development. The main trends of modern research and their connection with classical game theories, the role of culturalhistorical approach and the contribution of E.O. Smirnova to the study of play are shown.
Estimating survival rates of franciscana by fitting the Siler model to data on age-at-death of beachcast and bycatch and by a modelling approach using life tables of similar species: a comparison

For cetaceans, survival has been estimated from several different types of data, including a) age-distribution of catch data during commercial whaling; b) age-distribution of animals killed in drive fishery; c) individual based mark-recapture models of photoidentified animals; d) using a range of life tables of several species with similar life histories; and e) fitting Siler (1979) competing-risk models to age-at-death data. All these approaches rely on assumptions that, in many cases, are difficult to satisfy. For several reasons the use of mark-recapture techniques is unsuitable for franciscana. Age distribution data of bycatch has not been used so far for any cetacean species because of the unequal vulnerability of different age classes. Beachcast data are typically biased, as naturally-killed dolphins and bycatch are mixed in unknown proportions. In this study we developed a method that combines age distribution data of bycatch and beachcast animals to identify and adjust the bias. Once the bias is adjusted, the age distribution data were fitted by the Siler model and survival rates of franciscana were estimated. Results were compared to those obtained from an alternative approach of using life tables from similar species to estimate survival rates of franciscana. The two methods resulted in identical mean survival rates for juvenile franciscana (i.e. 0.91 and 0.90). The values for adults were also identical when the age-at-death data was truncated at age 14 (i.e. 0.854 and 0.86). This suggests that bycatch age-at-death data, after careful treatment to reduce bias effects, may be useful to estimate approximate survival rates.
OTT_A_240973 4271..4282

Zhou Jiang Pu Cheng Biyuan Luo Jian Huang 1Department of Breast Surgery, Second Affiliated Hospital, Zhejiang University School of Medicine; Key Laboratory of Tumor Microenvironment and Immune Therapy of Zhejiang Province, Hangzhou, Zhejiang, People’s Republic of China; 2Department of Gynecology, Second Affiliated Hospital, Zhejiang University School of Medicine; Key Laboratory of Tumor Microenvironment and Immune Therapy of Zhejiang Province, Hangzhou, Zhejiang, People’s Republic of China; 3Cancer Center, Xiangya 2nd Hospital, Central South University, Changsha, Hunan, People’s Republic of China Purpose: To construct a competing endogenous RNA (ceRNA) topology network of RNAseq data and micro RNA-seq (miRNA-seq) data to identify key prognostic long non-coding RNA (lncRNAs) in luminal breast cancer, and validate the results by human luminal breast cancer samples. Materials and Methods: The RNA-seq data and miRNA-seq data of luminal A breast cancer in the The Cancer Genome Atlas (TCGA) database were downloaded and compared with those in the miRcode database to obtain lncRNA–miRNA relationship pairs. Final target genes were predicted by all three databases (miRDB, miRTarBase, and TargetScan), thereby obtaining the miRNA-messenger RNA (miRNA-mRNA) relationship pairs and a ceRNA topology network was constructed, then mRNA enrichment analysis, ceRNA topological and stability analysis, univariate and multivariate Cox regression analysis were performed. Overall survival (OS) was evaluated and the key prognostic RNAs were identified. The expression difference between normal and tumor, as well as the correlation of high expression in tumor with pathological parameters (Ki-67, Grade, tumor diameter) were validated by human breast cancer specimens. Results: A ceRNA topology network was constructed and six lncRNAs were finally identified (The higher expression of PART1, IGF2.AS, WT1.AS, OIP5.AS1, and SLC25A5. AS1 was associated with poor prognosis while AL035706.1 was adverse) and the poor prognostic ones were higher expressed in tumor tissue and correlated with a higher Ki-67 (>10%), tumor grades (II, III) and tumor diameters (>1.5 cm). Using six lncRNAs, we constructed a prognostic model, which performed well for the classification of prognosis in the module. Conclusion: We identified and verified six biomarkers (OS-predicting) in luminal breast cancer, which significantly enriched the prediction and potential targets of this subtype.
Synthesis and Characterization of CdS Nanoparticles Obtained in Star-Like Dextran-Graft-Polyacrylamide Matrices

A. NAUMENKO, N. KUTSEVOL, V. CHUMACHENKO, V. PASHCHENKO, S. KUTOVYY, M. RAWISO 3 1 Faculty of Physics, Taras Shevchenko National University of Kyiv (64/13, Volodymyrs’ka Str., Kyiv 01601, Ukraine) 2 Faculty of Chemistry, Taras Shevchenko National University of Kyiv (64/13, Volodymyrs’ka Str., Kyiv 01601, Ukraine) 3 Institut Charles Sadron (CNRS-UdS) (23, rue du Loess-BP 84047, 67034 Strasbourg, Cedex 2, France)
PENGARUH PEMBERIAN PUPUK UREA DAN PUPUK KANDANG AYAM TERHADAP PERTUMBUHAN DAN HASIL TANAMAN JAGUNG MANIS (Zea mays Saccharata Sturt.L) Varietas Gendis

This research have go to influence interaction between urea fertilizer and chicken manure, also best small boxist to growing and result Sweet corn (Zea mays saccharata sturt . L) gendis's variety . This research is done with to use it Group Random Planing that be arranged according to Factorial (RAKF) with 2 factor, first factor that is urea's fertilizer (U) that consist from 3 level that is urea 0 Kg/ha (U0 /control), urea 100 Kg/ha (U1), urea 200 Kg/ha (U2), urea 300 Kg/ha (U3). second Factor that is chicken manure (A) consist from 3 level that is : chicken manure 0 Kg/ha (A0 /control), chicken manure 10 Ton/ha (A1), chicken manure 20 Ton/ha (A2). Variable that to be perceived to cover high of plants, leaf number, heavy , long of tuna and tuna diameter. The data is analyzed with to use it Analisis Of Varian (ANOVA), if influency to be continued with test DMRT 5%. Research result to show that : 1). Interaction between urea's fertilizer 200 kg/ha and chicken manure 20 ton/ha give it best influence in growing and plants result sweet corn. 2 ) fertilizer Giving urea 200 kg/ha gave best influence in growing and plants result sweet corn. 3). the Giving of chicken manure 20 ton/ha give it best influence in growing and plants result sweet corn
Electro‐Oxidation of Methanol and Ethanol Catalyzed by Pt/ZSM‐5/C

Direct alcohol fuel cells are a promising source of future energy generation for small and portable devices. Platinum is considered the best catalyst for electro-oxidation of alcohols in fuel cells but the major hurdles with platinum catalysts are high cost of platinum as well as low selectivity, slow reaction kinetics and carbonaceous poisoning associated with platinum. This particular research reports electro-oxidation of methanol and ethanol over platinum electrodeposited on ZSM-5 without any carbon additive. From the cyclic voltammetry and chronoamperometry, linear sweep voltammetry, tafel plot and multiple scan analyses, it is found that Pt/ZSM-5/C electrodes can catalyze electro-oxidation of methanol and ethanol with higher efficiency. ZSM-5 supports the formation of smaller sized platinum nanoparticles in a dispersed manner on the zeolite support and thus increases the active surface area of the metal for catalytic activity. It favors adsorption of alcohol molecules on the modified electrode surface and thus increases the diffusion process. It also stabilizes the modified electrodes.
Optimal Robot Human Handover Velocity vorgelegt

Human-robot handover plays a central role in many human-robot collaboration tasks. Choosing the proper velocity for the handover trajectory of a robot giver is vital for the handover’s performance. The trajectory could be slow and bore or even hinder the performance of its partner. Executing a too fast trajectory could lead to a less fluent handover. This thesis studied the effect of the Cartesian velocity of the handover trajectory of the robot giver.
Measurement of Black Carbon Emissions from Multiple Engine and Source Types using Laser-Induced Incandescence: Sensitivity to Laser Fluence

Abstract. A new regulatory standard for non-volatile particulate matter (nvPM) mass concentration emissions from aircraft engines has been adopted by the International Civil Aviation Organisation. One of the instruments used for the regulatory nvPM mass emissions measurements in aircraft engine certification tests is the Artium Technologies LII 300, which is based on laser-induced incandescence. The LII 300 has been shown in some cases to demonstrate a variation in response to the type of black carbon particle measured. Hence it is important to identify a suitable black carbon emission source for instrument calibration. In this study, the relationship between the nvPM emissions produced by different engine sources and the response of the LII 300 instrument utilising auto-compensating laser-induced incandescence (AC-LII) method was investigated. Six different sources were used, including a turboshaft helicopter engine, a diesel generator, an intermediate pressure test rig of a single sector combustor, an auxiliary power unit gas turbine engine, a medium-sized diesel engine, and a downsized turbocharged direct injection gasoline engine. Optimum LII 300 laser fluence levels were determined for each source and operating condition evaluated. It was found that an optimised laser fluence can be valid for real-time measurements from a variety of sources, where the mass concentration was independent of laser fluence levels covering the typical operating ranges for the various sources. However, it is important to perform laser fluence sweeps to determine the optimum fluence range, as differences were observed in the laser fluence required, between sources and fuels. We discuss the measurement merits, variability, and best practices in the real-time quantification of nvPM mass concentration using the LII 300 instrument, and compare that with other diagnostic techniques, namely absorption–based methods such as photoacoustic spectroscopy using a photoacoustic extinctiometer (PAX) and a Micro Soot Sensor (MSS), and thermal-optical analysis (TOA). Particle size distributions were also measured using a scanning mobility particle sizer (SMPS). Overall, the LII 300 provides robust and consistent results when compared with the other diagnostic techniques across multiple engine sources and fuels. The results from this study will inform the development of updated calibration protocols to ensure repeatable and reproducible measurements of nvPM mass emissions from aircraft engines using the LII 300.
Evolution of Contagion by COVID-19 in El Salvador Applying SIR-Dynamic Simulations with the Monte Carlo Method

The COVID-19 pandemic is at the present in full swing in El Salvador and experience in other countries forces us to make drastic public and health policy decisions to contain the disease. This report presents some estimates of the evolution of the disease under the conditions of social distancing and home quarantine ordered by the authorities. Estimates and projections provide evidence based on SIR-type mathematical models, applying the Monte Carlo method, to establish and evaluate the critical phases of the pandemic and its effects, so that more efficient measures and strategies can be re-evaluated to continue containing the entry into greater critical phases. The time-dependent SIR was used to calculate differents paramenters of pandemic in the country, using official data from March 18 up May 4. We found the recovery rate has a value of α̂ = (0.0658 ± 0.0267)1/t with t measured in days, while the transmision rate is β̂ = (0.108 ± 0.001)1/t, therefore, the basic reproduction number was calculated with the value of R̂0 = (3.18 ± 0.21). The time-dependent SIR also was used to calculate the projections for infected cases and recovered cases, however, we analyzed the implementation of the Monte Carlo method in the numerical solution of infected cases. The maximum peak of the contagion is calculated using the solutions for infected cases, with and without applying Monte Carlo method, and it predicts between 1,320 and 1,488 individuals in infected state, and projecting that the time window for the critical period of the epidemic will be between the first and second week of June, while it would be attenuating only in mid-August. The error analysis include the error by the parameters and the prediction error.
The sound radiation of musical instruments at the transition from near field to far field

Musical instruments have complex radiation patterns that vary at different points of observation relative to the source. Usually directivity patterns are measured at one specific distance in the far field. Although in practice musical instruments are often recorded with very close positioned microphones, there is very little data on their radiation patterns in the near field as the interferences of sound waves are very complex. To gather more data in the near-field and investigate the transition from near to far field, magnitude spectra of four different instruments playing single notes recorded at various distances with a multi-channel microphone line array in an anechoic room are analyzed.
OTT_A_240803 2807..2817

Qingyun Zhu Yuehui Guo Shiwei Chen Daiquan Fu Yanxiang Li Zhi Li Caifang Ni 1Department of Interventional Radiology, The First Affiliated Hospital of Soochow University, Suzhou 215006, People’s Republic of China; 2Department of Intervention, Gongli Hospital of Shanghai Pudong New Area, Shanghai 200135, People’s Republic of China Background: Irinotecan (IRI) is considered an option for second-line treatment of advanced gastric cancer; however, acquired drug resistance currently limits its clinical application. Recently, many researchers have shown that autophagy plays a crucial role in the resistance of tumor cells to chemotherapy and radiotherapy. In this study, we investigated the relationship between autophagy and antitumor activity of IRI in gastric cancer cells. Methods: We used MTT assay, flow cytometry and immunofluorescence staining to detect viability, apoptosis and autophagy in gastric cancer. Western blotting assay was used to determine the expression of LC3, Beclin-1, P62, cleaved PARP and Caspase 3. In vivo animal study was performed finally. Results: We found that IRI treatment doseand time-dependently inhibited growth and induced apoptosis in gastric cancer cells. Moreover, IRI treatment caused autophagy in these cells, whereas autophagy inhibitors—3-methyladenine (3-MA), chloroquine (CQ), and Beclin-1 small interfering RNA (siRNA)—suppressed cytotoxicity of IRI. A mechanistic analysis showed that IRI-induced autophagy and apoptosis were related to increased reactive oxygen species (ROS) accumulation and activation of the JNKand p38-MAPK pathways. Further in vivo experiments revealed that IRI suppressed tumor growth, induced autophagy, and stimulated the JNKand p38-MAPK pathways, whereas 3-MA attenuated these effects. Conclusion: Taken together, these results indicate that IRI stimulates the ROS-related JNKand p38-MAPK pathways to promote autophagy-dependent apoptosis. Thus, a combination of IRI with a pharmacological autophagy enhancer may be a promising therapeutic strategy against gastric cancer.
Gradient Descent Based Hyparameter Tuning of Xception Architecture for Diabetic Retinopathy Segmentation and Classification

Diabetic retinopathy (DR) is a widespread difficulty of diabetes and is considered as a main reason for vision loss in all over the globe. Several difficulties of DR can be avoided by controlling blood glucose level and timely medication. In real time, it is difficult to detect the DR and consumes more time in a manual way. This paper introduces a new Gradient Descent (GD) based Hyper parameter tuned Xception model called GD-Xception model to detect and classify DR images in an effective way. The GD-Xception model involves a series of subprocesses namely preprocessing, segmentation, feature extraction and classification. A set of extensive simulation takes place to ensure the effective outcome of the presented GD-Xception model. The presented model is tested using a DR dataset from Kaggle. The extensive experimental study clearly portrayed the superior outcome of the GD-Xception model with the maximum accuracy, sensitivity and specificity of 99.39%, 98.50% and 99.62% respectively.
Bilayer Electrolyte Thin Films Gadolinia Doped Ceria /Yttria Stabilized Zirconia Prepared by Pulsed Laser Deposition for Electrochemichal Devices

In this paper bilayer thin films of 10CGO/8YSZ electrolyte with enhanced O conductivity composed of gadolinia doped CeO2 (Ce0,9Gd0,1O2-) and yttria stabilized zirconia 8 mol% Y2O3 doped ZrO2 layers were deposited by Pulsed Laser Deposition (PLD) using various numbers of pulses. This composite has supplementary function in electrochemical devices because 10 CGO can act as interdiffusion barrier with cathode materials. The structure and morphology of these thin films, having thicknesses smaller than 1μm, were investigated by X-ray diffraction (XRD), scanning electron microscopy (SEM) and atomic force microscopy (AFM). The XRD patterns exhibit cubic fluorite structure with a sharp (111) peak. The grain size was found to depend on the thickness. Optical characterization was carried out by spectroscopic ellipsometry (SE) using the Tauc-Lorentz model.
A hybrid sequential data assimilation scheme for model state and parameter estimation

We present a new hybrid method for concurrent model state and parameter estimation. The new algorithm uses ideas from three dimensional variational data assimilation (3D Var) and the extended Kalman ﬁlter (EKF) together with the technique of state augmentation to estimate uncertain model parameters alongside the model state variables in a sequential assimilation-forecast system. The method is relatively simple to implement and computationally inexpensive to run. We demonstrate its eﬃcacy via a series of identical twin experiments with three simple dynamical system models. The scheme is able to recover the true parameter values to a good level of accuracy, even when observational data are noisy. We expect this new technique to be easily transferable to larger, more complex models.