Miracle-dz/UniFAR-FTUs huggingface dataset:
Design and Implementation of a Robust System to Measure GSM Radiation using Microstrip Antenna on a Foam Substrate

This work presents design, analysis and implementation of a robust system to measure the power of the signal in the GSM range varying from 890 to 960 MHz. The system is composed of microstrip antenna on a foam substrate, RF detector, low pass filter, amplifier, analog to digital converter, and finally digital interface with a PC. As for the antenna, we designed and implemented microstrip antenna with bandwidth of 8% using foam as dielectric substrate. We used the system to measure the power of the signal in different places at different times during the day. Using the system we assured that the signal varies depending on the traffic at different hues and the location with respect to the base station.
A Comparison of Children with Epilepsy to an Age- and IQ-Matched Control Group on the Children's Memory Scale

Past research has found that children with epilepsy exhibit decreased memory skills. In addition, some studies have found that children with epilepsy obtain significantly lower IQ scores than controls. In an effort to examine whether children with epilepsy have specific memory weaknesses versus global cognitive difficulties, the present study compared the performance of 62 children (age range = 6–16 years). Thirty-one children with epilepsy were compared to 31 age- and IQ-matched controls on the Children's Memory Scale (CMS) to determine whether differences in memory skills persist when IQ is matched. An independent t-test comparing index and scaled scores was performed. The results indicated that with the exception of the Word Pairs subtest (p < .01), children with epilepsy did not differ significantly on the CMS subtests when IQ was matched. This suggests that list-learning paradigms may be particularly sensitive to memory impairments in children with epilepsy and/or that children with epilepsy have more global cognitive impairments.
Regulation of Cardiovascular Functions by Eicosanoids and Other Lipid Mediators Cyclooxygenase-2 induction by bradykinin in aortic vascular smooth muscle cells

Rodriguez, Jorge A. , Paula De la Cerda, Eileen Collyer, Valerie Decap, Carlos P. Vio, and Victoria Velarde. Cyclooxygenase-2 induction by bradykinin in aortic vascular smooth muscle cells. Am J Physiol Heart Circ Physiol 290: H30–H36, 2006. First published September 2, 2005; doi:10.1152/ajpheart.00349. 2005. —Vascular smooth muscle cell proliferation and migration play an important role in the pathophysiology of several vascular diseases, including atherosclerosis. Prostaglandins that have been implicated in this process are synthesized by two isoforms of cyclooxygenase (COX), with the expression of the regulated COX-2 isoform increased in atherosclerotic plaques. Bradykinin (BK), a vasoactive peptide increased in inflammation, induces the formation of prostaglandins through specific receptor activation. We hypothesized that BK plays an important role in the regulation of COX-2, contributing to the increase in production of prostaglandins in vascular smooth muscle cells. Herein we examined the signaling pathways that participate in the BK regulation of COX-2 protein levels in primary cultured aortic vascular smooth muscle cells. We observed an increase in COX-2 protein levels induced by BK that was maximal at 24 h. This increase was blocked by a B2 kinin receptor antagonist but not a B1 receptor antagonist, suggesting that the B2 receptor is involved in this pathway. In addition, we conclude that the activation of mitogen-activated protein kinases p42/p44, protein kinase C, and nitric oxide synthase is necessary for the increase in COX-2 levels induced by BK because either of the specific inhibitors for these enzymes blocked the effect of BK. Using a similar approach, we further demonstrated that reactive oxygen species and cAMP were not mediators on this pathway. These results suggest that BK activates several intracellular pathways that act in combination to increase COX-2 protein levels. This study suggests a role for BK on the evolution of the atheromatous plaque by virtue of controlling the levels of COX-2.
Evolution of three-dimensional gravitational waves: Harmonic slicing case.

We perform numerical simulations of a three-dimensional (3D) time evolution of pure gravitational waves. We use a conformally flat and K=0 initial condition for the evolution of the spacetime. We adopt several slicing conditions to check whether a long time integration is possible in those conditions. For the case in which the amplitude of the gravitational waves is low, a long time integration is possible by using the harmonic slice and the maximal slice, while in the geodesic slice (\ensuremath{\alpha}=1) it is not possible. As in the axisymmetric case and also in the 3D case, gravitational waves with a sufficiently high amplitude collapse by their self-gravity and their final fates seem to be as black holes. In this case, the singularity avoidance property of the harmonic slice seems weak, so that it may be inappropriate for the formation problems of the black hole. By means of the gauge-invariant wave extraction technique we compute the waveform of the gravitational waves at an outer region. We find that the nonlinearity of Einstein gravity induces the higher multipole modes even if only a quadrupole mode exists initially.
Semantic Web Search Using Ontology Based Classification Algorithms: A Survey

Now-a-days the web based information is increasing day-by-day. As the number of internet users and the number of web document grows, it is difficult for users to find the documents that are relevant to their particular needs.In Recent years semantic web search is not considering semantic relations between words in traditional Machine Learning algorithms. Previous works on ontology-based semantic web search and web documents classification miss some important issues of dynamic ontology construction and ranking of classified documents. The WorldNet based relations are considered to relate the user queries with the web documents. There is no proper ontology construction is available. Understanding web pages and its contents are very much useful to get better . This paper analyzes which method is efficient ontology construction for creating semantic relation and classification of web document. This survey Recall , precision rates and similarity improvement methods are studied in detailed manner.This survey paper is used to find out the problems of web information gathering. Ontology plays important role in meaningful and context driven information retrieval. This provides meaningful search and displaying relevant documents. To find out relevant document Similarity measures and classification is used to classify the document according to user query. Finally the page ranking algorithm displays the search results based on page ranking.
Rap1 Activation Plays a Regulatory Role in Pancreatic Amylase Secretion*

Rap1 is a member of the Ras superfamily of small GTP-binding proteins and is localized on pancreatic zymogen granules. The current study was designed to determine whether GTP-Rap1 is involved in the regulation of amylase secretion. Rap1A/B and the two Rap1 guanine nucleotide exchange factors, Epac1 and CalDAG-GEF III, were identified in mouse pancreatic acini. A fraction of both Rap1 and Epac1 colocalized with amylase in zymogen granules, but only Rap1 was integral to the zymogen granule membranes. Stimulation with cholecystokinin (CCK), carbachol, and vasoactive intestinal peptide all induced Rap1 activation, as did calcium ionophore A23187, phorbol ester, forskolin, 8-bromo-cyclic AMP, and the Epac-specific cAMP analog 8-pCPT-2′-O-Me-cAMP. The phospholipase C inhibitor U-73122 abolished carbachol- but not forskolin-induced Rap1 activation. Co-stimulation with carbachol and 8-pCPT-2′-O-Me-cAMP led to an additive effect on Rap1 activation, whereas a synergistic effect was seen on amylase release. Although the protein kinase A inhibitor H-89 abolished forskolin-stimulated CREB phosphorylation, it did not modify forskolin-induced GTP-Rap1 levels, excluding PKA participation. Overexpression of Rap1 GTPase-activating protein, which blocked Rap1 activation, reduced the effect of 8-bromo-cyclic AMP, 8-pCPT-2′-O-Me-cAMP, and vasoactive intestinal peptide on amylase release by 60% and reduced CCK- as well as carbachol-stimulated pancreatic amylase release by 40%. These findings indicate that GTP-Rap1 is required for pancreatic amylase release. Rap1 activation not only mediates the cAMP-evoked response via Epac1 but is also involved in CCK- and carbachol-induced amylase release, with their action most likely mediated by CalDAG-GEF III.
Spontaneous and Continuous Cyclooxygenase-2-Dependent Prostaglandin E2 Production by Stromal Cells in the Murine Small Intestine Lamina Propria: Directing the Tone of the Intestinal Immune Response1

The mechanisms allowing the gastrointestinal immune system to avoid an inappropriate inflammatory response to nonpathogenic luminal Ags are poorly understood. We have previously described a role for cyclooxygenase (COX)-2-dependent arachidonic acid metabolites produced by the murine small intestine lamina propria in controlling the immune response to a dietary Ag. To better understand the role of COX-2-dependent arachidonic acid metabolites produced by the lamina propria, we examined the pattern of expression and the cellular source of COX-2 and COX-2-dependent PGE2. We now demonstrate that non-bone marrow-derived lamina propria stromal cells have basal COX-2 expression and that COX-2-dependent PGE2 production by these cells is spontaneous and continuous. The other mucosal and nonmucosal lymphoid compartments examined do not share this phenotype. In contrast to the majority of descriptions of COX-2 expression, COX-2 expression by lamina propria stromal cells is not dependent upon exogenous stimuli, including adhesion, LPS signaling via Toll-like receptor 4, or the proinflammatory cytokines TNF-α, IFN-γ, and IL-1β. These findings, in conjunction with the known immunomodulatory capacities of PGs, suggest that COX-2 expression by the small intestine lamina propria is a basal state contributing to the hyporesponsiveness of the intestinal immune response.
Influence of Dynamics and Trajectory on Integrated GPS/INS Navigation Performance

The integrated GPS/INS system has become an indispensable tool for providing precise and continuous position, velocity, and attitude information for many positioning and navigation applications. Therefore, it is important to gain insights into the characteristics of the integrated GPS/INS system performance, particularly their relationships with key operational factors, such as the trajectory and dynamics. Such knowledge can be used to improve the quality of positioning and navigation results from integrated GPS/INS systems. In order to analyse the influence of vehicle dynamics and trajectory, simulation and field tests have been carried out in this research. The test results show that the vehicle dynamic changes significantly affect the Kalman filter initialisation time and estimation performance depending on the system operational environments.
Emerging viral diseases in kidney transplant recipients

Viruses are the most important cause of infections and a major source of mortality in Kidney Transplant Recipients (KTRs). These patients may acquire viral infections through exogenous routes including community exposure, donor organs, and blood products or by endogenous reactivation of latent viruses. Beside major opportunistic infections due to CMV and EBV and viral hepatitis B and C, several viral diseases have recently emerged in KTRs. New medical practices or technologies, implementation of new diagnostic tools, and improved medical information have contributed to the emergence of these viral diseases in this special population.
How effective is acupuncture in the management of pain?

fered a myocardial infarction would be facilitated by better communication between the general practitioner who has the key role, the hospital and the doctor working in industry. Following the symposium, a brief questionnaire completed by participants showed that more than half had changed their practice in direct response to what they had heard. The most frequently cited changes were those related to getting people back to work and their normal duties much earlier than before, certainly by six weeks after uncomplicated myocardial infarction or cardiac surgery.
Towards Service-Based Database Management Systems

Today’s database management systems are mainly large and heavy-weight monoliths that, even worse, undergo steady extensions in functionality. This makes them highly complex and creates problems when it comes to build tailored extensions. Our goal is to introduce more flexibility and extensibility by founding our database architecture on the principles of Service Oriented Architecture (SOA). In this paper, we present a Service-Based Data Management System (SBDMS) architecture that supports extensions according to user requirements. The architecture we propose consists of four major service layers (Storage Services, Access Services, Data Services, Extension Services). Each of these layers can flexibly be extended with new services that invoke other services from within or outside the system. In addition, the architecture’s extension mechanism allows application functionality to be easily integrated into the Service-Based Data Management System to support reuse and optimization of commonly used application functionality.
Effectiveness of Performance Feedback in Stimulating User-Generated Content

This study investigates whether and how a platform’s provision of performance feedback to users about their prior content contributions can help to stimulate users’ subsequent contributions. We draw on social value orientation theory to hypothesize how different framings may impact users’ likelihood of producing additional content. We partnered with a major mobile crowdsourcing platform based in China to conduct a randomized field experiment involving the delivery of feedback messages with randomly determined framings, via mobile push notifications. We find that feedback framed either pro-socially or pro-self has a positive effect on content contributions, whereas feedback framed competitively has no such effect. Additionally, we observe differences across genders, such that the positive effects of pro-socially framed feedback are significantly stronger for female users. In contrast, competitively framed feedback is only effective for male users. Our findings provide implications for the design of platform-provided performance feedback to stimulate users' content contribution.
Hospital Surge Capacity: A Web-Based Simulation Tool for Emergency Planners

Abstract The National Center for the Study of Preparedness and Catastrophic Event Response (PACER) has created a publicly available simulation tool called Surge (accessible at http://www.pacerapps.org) to estimate surge capacity for user-defined hospitals. Based on user input, a Monte Carlo simulation algorithm forecasts available hospital bed capacity over a 7-day period and iteratively assesses the ability to accommodate disaster patients. Currently, the tool can simulate bed capacity for acute mass casualty events (such as explosions) only and does not specifically simulate staff and supply inventory. Strategies to expand hospital capacity, such as (1) opening unlicensed beds, (2) canceling elective admissions, and (3) implementing reverse triage, can be interactively evaluated. In the present application of the tool, various response strategies were systematically investigated for 3 nationally representative hospital settings (large urban, midsize community, small rural). The simulation experiments estimated baseline surge capacity between 7% (large hospitals) and 22% (small hospitals) of staffed beds. Combining all response strategies simulated surge capacity between 30% and 40% of staffed beds. Response strategies were more impactful in the large urban hospital simulation owing to higher baseline occupancy and greater proportion of elective admissions. The publicly available Surge tool enables proactive assessment of hospital surge capacity to support improved decision-making for disaster response. (Disaster Med Public Health Preparedness. 2018;12:513–522)
Rac1 and Toll-IL-1 Receptor Domain-Containing Adapter Protein Mediate Toll-Like Receptor 4 Induction of HIV-Long Terminal Repeat1

Opportunistic infections, common in HIV-1-infected patients, increase HIV replication; however, the intracellular signaling mechanisms involved are not clearly known. We have shown that Toll-like receptor 2 (TLR2), TLR4, and TLR9 mediate microbial Ag-induced HIV-long terminal repeat (HIV-LTR) trans-activation and HIV-1 replication, and that LPS-induced HIV-LTR trans-activation is mediated through myeloid differentiation adapter protein. Recently, Toll-IL-1R domain-containing adapter protein (TIRAP) has been identified as an adapter molecule that mediates responses to TLR2 and TLR4 ligands, and TIRAP was suggested to provide signaling specificity for different TLRs. Rac1, a small GTP-binding protein that is activated upon LPS stimulation of macrophages, activates phosphatidylinositol 3-kinase and Akt and leads to NF-κB activation. The roles of Rac1 and TIRAP in LPS activation of HIV replication is not known. In the present study we show that LPS stimulation of human microvessel endothelial cells leads to Rac1 activation. Constitutively active Rac1 (Rac1V12) simulated the effect of LPS to activate HIV-LTR, whereas the expression of dominant negative Rac1 (Rac1N17) partially blocked LPS-induced HIV-LTR trans-activation. Rac1V12-induced HIV-LTR activation was independent of myeloid differentiation adapter protein, and dominant negative TIRAP blocked Rac1V12-induced HIV-LTR trans-activation. In this study we show for the first time that activation of Rac1 leads to HIV-LTR trans-activation, and this is mediated through TIRAP. Together these results underscore the importance of Rac1 and TIRAP in TLR4 activation of HIV replication and help delineate the signaling pathways induced by TLRs to mediate microbial Ag-induced HIV replication and HIV pathogenesis.
Effects of Noise Source Configuration on Directional Benefit Using Symmetric and Asymmetric Directional Hearing Aid Fittings

Objective: The benefits of directional processing in hearing aids are well documented in laboratory settings. Likewise, substantial research has shown that speech understanding is optimized in many settings when listening binaurally. Although these findings suggest that speech understanding would be optimized by using bilateral directional technology (e.g., a symmetric directional fitting), recent research suggests similar performance with an asymmetrical fitting (directional in one ear and omnidirectional in the other). The purpose of this study was to explore the benefits of using bilateral directional processing, as opposed to an asymmetric fitting, in environments where the primary speech and noise sources come from different directions. Design: Sixteen older adults with mild-to-severe sensorineural hearing loss (SNHL) were recruited for the study. Aided sentence recognition using the Hearing in Noise Test (HINT) was assessed in a moderately reverberant room, in three different speech and noise conditions in which the locations of the speech and noise sources were varied. In each speech and noise condition, speech understanding was assessed in four different microphone modes (bilateral omnidirectional mode; bilateral directional mode; directional mode left and omnidirectional mode right; omnidirectional mode left and directional mode right). The benefits and limitations of bilateral directional processing were assessed by comparing HINT thresholds across the various symmetric and asymmetric microphone processing conditions. Results: Study results revealed directional benefit varied based on microphone mode symmetry (i.e., symmetric versus asymmetric directional processing) and the specific speech and noise configuration. In noise configurations in which the speech was located in the front of the listener and the noise was located to the side or surrounded the listener, maximum directional benefit (approximately 3.3 dB) was observed with the symmetric directional fitting. HINT thresholds obtained when using bilateral directional processing were approximately 1.4 dB better than when an asymmetric fitting (directional processing in only one ear) was used. When speech was located on the side of the listener, the use of directional processing on the ear near the speech significantly reduced speech understanding. Conclusions: Although directional benefit is present in asymmetric fittings, the use of bilateral directional processing optimizes speech understanding in noise conditions in which the speech comes from in front of the listener and the noise sources are located to the side of or surround the listener. In situations in which the speech is located to the side of the listener, the use of directional processing on the ear adjacent to the speaker is likely to reduce speech audibility and thus degrade speech understanding.
One-Part Geopolymer Mixes from Geothermal Silica and Sodium Aluminate

In geopolymer technology, silicate solutions are frequently used as alkali activators to dissolve the solid aluminosilicate precursor and aid in binder formation. These corrosive and often viscous solutions are not user-friendly and would be difficult to use for bulk production. Developing geopolymers as a one-part mixture (“just add water”), similar to Portland cement, increases their commercial viability. Here, for the first time, the geopolymer system consisting of geothermal silica and solid sodium aluminate (providing the solid silica, alkali, and alumina sources) is studied. The effects of water content, high early silica, and high early alumina in the formation of one-part mix geopolymers are also investigated. This system demonstrates that making geopolymers from solid sources by “just adding water” is possible. XRD shows that the formulation with less water has an unexpected greater extent of crystallinity. It is also observed that a high early Al concentration inhibits geopolymerization, while a.
Hepatitis C virus NS 2 is a protease stimulated by cofactor domains in NS 3

aInstitute for Virology and Cell Biology, University of Lübeck, D-23562 Lübeck, Germany; bInstitute for Virology, Faculty of Veterinary Medicine, Justus-Liebig-University, 35392 Giessen, Germany; and cInstitut de Biologie et Chimie des Protéines, Unité Mixte de Recherche 5086, Centre National de la Recherche Scientifique, Université de Lyon, IFR 128 Biosciences Gerland-Lyon Sud, F69397 Lyon, France