Miracle-dz/UniFAR-FTUs huggingface dataset:
Obtención y caracterización de andamios electrohilados a base de

silkworm (Bombyx mori different mixtures of QS and FGS. They were characterized with analytical techniques such as scanning electron microscopy-SEM, infrared spectroscopy-FTIR, X-ray diffraction-XRD, Thermogravimetric Analysis-TGA, Differential Scanning Calorimetry-DSC and Citocompatibility tests, to determine its morphology, functional groups, thermal transitions, and cell viability of the scaffolding nanometric diameters less than 200 nm, which allow optimal cell adhesion and thermal stability at the application site, with a view to control the degradation of the scaffold. Thermal analyses, supplemented with XRD studies reveal the internal structure of the for tissue engineering in biomedical applications such as scaffolds.
Autonomous Tracking by an Adaptable Scaled KCF Algorithm

A multicopter is equipped by a passive tracking device to follow a specified target. However, if want to track a non-controlled target, the passive tracking device is failed. We propose a vision-based tracking system for multicopters, used computer vision method to track any target without additional tracking devices. In this study, propose scale candidate graphs and scale tables to improve KCF. There are also stable results when the scale changes. The proposed an adaptable scaled KCF algorithm, when the KCF tracking failed, a feature-based matching detector is used to re-detect the target. Several experiments on various scene based on the proposed approach were conducted and evaluated. Stable tracking results were obtain to show the feasibility of the proposed system.
The resolution of immunofluorescent pathological images affects diagnosis for not only artificial intelligence but also human

Implication for health policy/practice/research/medical education: We examined how the image resolution affects the diagnosis not only artificial intelligence but also nephrologists in this study. The differences between human and artificial intelligence is specificity on diiferent resolution image diagnosis. The resolution of images might be important for not artificial intelligence but human on the point of specificity. Please cite this paper as: Takahashi K, Kitamura S, Fukushima K, Sang Y, Tsuji K, Wada J. The resolution of immunofluorescent pathological images affects diagnosis for not only artificial intelligence but also human. J Nephropathol. 2021;10(3):e26. DOI: 10.34172/jnp.2021. 26. ARTICLE INFO
Chemical Characteristics and Sensory Properties of Novel Snacks Produced with Okara Fortified with Omega-3 from Fish Oil

The aim of the present work was to develop a new soy-based food product and evaluate its chemical and sensory properties. A soy-based snack was mixed with rice ( Oryza sativa ), fortified with eicos-apentaenoic acid (EPA) and docosahexaenoic acid (DHA) Omega-3 fatty acids from fish by-products in encapsulated and emulsion form. Soy beans were subjected to grinding processes, maceration in pure distilled water, filtration and pasteurization, to obtain vegetable drinks and generate solid residue. Finally, a sensory analysis of the product obtained was carried out. The snacks protein content was around 17%. From the sensory evaluation, it could be concluded that the snacks with 50% of okara had great acceptability and the addition of Omega-3 was also acceptable. So, okara represents an excellent raw material that can be utilized for dietary protein fortification. On the other hand, it proposes based on soy and fish by-products allow sustainable development and contribute to the economy of each sector.
Evaluation of antimicrobial resistance in urinary isolates of member of enterobacteriaceae among woman attending Tertiary Care Hospital

Introduction: 1. Urinary Tract Infections (UTIs) are one of the most common urogenital infections and affects all age groups including men, women and children worldwide. 2. Urinary tract infections are a major public health problem in terms of morbidity and financial cost and incur the highest total health care cost among urological diseases. 3. UTI represents one of the most common disease/syndrome encountered in medical practice today with an estimated 150 million UTIs per annum worldwide. Materials and Method: A total of 300 mid-stream urine specimen from woman patient received in the department after collection in a sterile container were received processed by semi quantitative culture technique using a standard calibrated loop (diameter 0.04mm) on blood agar (BA) and MacConkey agar (MA). After 24hr of aerobic incubation at 37°C, culture growth showing significant bacteriuria were included in the study for further processing. Standard biochemical test of identification were used to identify bacterial isolates. Antimicrobial susceptibility was determined by Kirby-Bauer disk diffusion method as per CLSI Recommendations. Result: Out of 300 urine samples received Significant Growth was seen in 134 (44.67%) samples, whereas 166 (55.33%) samples showed either Insignificant Growth (polymicrobial) or showed no Growth. Conclusion: The restricted use of antibiotics can lead to the withdrawal of selective pressure and the resistant bacteria will no longer have a survival advantage against these antibiotics. Hence, there is a need to formulate strategies to detect and prevent the emergence of resistance for an effective treatment of the urinary tract infection.
Experimental and theoretical investigation of clemastine drug for corrosion protection of carbon steel in sulfuric acid solution

Polarization and electrochemical impedance spectroscopy (EIS) were employed for investigating the behavior of clemastine drug on the corrosion protection of carbon steel in 0.5 M H2SO4 solution which was enhanced by increasing the clemastine concentration in acid solution. As evidenced by polarization data, clemastine behaved as a mixed-type inhibitor and retards both anodic and cathodic processes. Adsorption of clemastine on carbon steel in acid solution obeyed the Langmuir adsorption isotherm. A reasonable correlation was observed between the ∆Goads values obtained from EIS and potentiodynamic polarization measurements. The calculated ∆Goads values of clemastine confirmed comprehensive adsorption that is a combination of physical and chemical adsorption. The electronic properties of clemastine were calculated via density functional theory (DFT) approach to establish the relationship between the inhibitive effect and molecular structure of the clemastine. According to the obtained quantum chemical parameters, clemastine showed higher EHOMO, lower EHOMO, lower energy gap, and higher dipole moment than some inhibitors earlier reported as good corrosion inhibitors.
PKC ζ ‐ dependent upregulation of p 27 kip 1 contributes to oxidative stress induced retinal pigment epithelial cell

Multinucleate cells, i.e., multiple nuclei share one common cytoplasm, are frequently observed in various patho-physiological conditions, including development, aging, inflammation and malignant tumor. Multinucleate cells can be induced by the fusion of multiple cells or formed by nuclear division that is not followed by cytokinesis [1]. During inflammation, such as infection from tuberculosis, herpes, HIV, or foreign bodies, macrophages can be multinucleated [2]. Inflammation-induced microglia multinucleation is known to be due to cytokinesis failure [3]. Age-related multinucleate cells have been observed in various tissues and cells, such as vascular endothelial cells [4] and retinal pigment epithelial (RPE) cells [5].
Wind Power Prediction and Early Downtime Detection for Ireland

Wind energy must be commercially competitive to be economically sustainable. Existing wind farms in Ireland must be more efficient to meet the 2009 EU Renewable Energy Directive target of 7% of total energy demand from onshore wind energy farms, which is 45% of the total national renewable energy target of 16%. WindPearl a Sustainable Energy Authority of Ireland (SEAI) funded project is currently looking into improving Operations & Maintenance (O&M) of onshore wind turbine farms in Ireland. WindPearl uses bespoke data analytics, focusing on early and accurate downtime prediction with significantly improved wind turbine power curve forecasts. Both have real-time capabilities and adaptable to uncertain, imperfect, or poor data. The project, a combination of feasibility study and demonstration, uses real data from several wind farms in Ireland covering an entire range of manufacturers. Improved methodologies of wind power prediction are being developed, calibrated, and implemented for wind farms to demonstrate the improvement of operations and maintenance. The ability of replication, transferability and scalability are being established.
Evaluation of the Effects of Letrozole in Combination with Neoadjuvant Chemotherapy on Clinical Response Rate of Breast Cancer

AbstractThis randomized clinical trial was aimed to assess the efficacy of neoadjuvant letrozole in combination with standard neoadjuvant chemotherapy regimen on clinical response rate of hormone receptor positive locally advanced breast cancer.In this randomized clinical study, 42 female patients, ≥ 18 years, with clinical stage IIB-IIIC (T1-4, N0-3, M0), pathologically proven hormone receptor positive and HER2 negative, invasive ductal carcinoma of breast, were randomly assigned to receive standard neoadjuvant chemotherapy alone (control group) or letrozole 2.5 mg/d (in association with goserlin in premenopausal patients) concurrent with standard neoadjuvant chemotherapy (study group). Standard neoadjuvant chemotherapy regimen has consisted of 4 cycles of doxorubicin (60mg/m2) and cyclophodphamide (600mg/m2), followed by 4 cycles of paclitaxel (175mg/m2) every two weeks.At the beginning of the study all patients underwent thorough exmination of breast mass and axillary lymph nudes by palpation and ultrasonography. At the end of the study response rates were also evaluated by palpation and ultrasonography and subsequently patients were referred for surgury. Pathologic response rates were also evaluated on surgical specimens. All of the clinical, ultrasonographic and pathologic examinations during the trial were performed by a single specialist. Finally all the data were analysed statistically.Overall clinical response rates in breast were 95.2%, in both study and control group. Overall clinical response rates in axilla were 80.9% and 76.2% in study and control group respectively. Similarly, overall radiologic complete response rates in breast and axilla were 95.2% and 76.2% respectively in both study and control group. Totally, the comparison of overall clinical and radiologic response rates in th breast and axilla, showed no significant difference between control and study group (p>0.05). The addition of letrozol to standard neoadjuvant chemotherapy regimen was not associated with higher clinical and radiologic response rates in patients with locally advanced hormon receptor positive breast cancer.Keywords: Neoadjuvant chemotherapy, Letrozole, Locally advanced breast cancer
130-Article Text-803-1-6-20200206 (1).cdr

Advances in Basic Medical Sciences Antioxidant Effects of Spinach on Intra-testicular Testosterone Levels in Obese Rats ORIGINAL ARTICLE 1 2 3 Somia Iqbal *, Shazia Ali , Arif Siddiqui 1 Department of Physiology, Wah Medical College, Wah Cantt, Pakistan. Department of Physiology, Islamic International Medical College, Riphah International university, Rawapindi, Pakistan. Barrett Hodgson University, Karachi, Pakistan. 2
Enhancing semantic belief function to handle decision conflicts in SoS using k-means clustering

Background The endeavouring to offer complex special functions from individual systems gave rise to what is known as the System of Systems (SoS). SoS co-integrating systems together while allowing for absorbing more systems in the future. SoS as an integrated system simplifies operations, reduces costs, and ensures efficiency. However, conflict may result while co-integrating systems, violating the main benefits of SoS. This paper is concerned with enhancing the time required to detect and solve such conflicts. Methods We adopted the k-means clustering technique to enhance the detection and solving of conflict resulting while co-integrating new systems into an existing SoS. Instead of dealing with SoS as a single entity, we partition it into clusters. Each cluster contains nearby systems according to pre-specified criteria. We can consider each cluster a Sub SoS (S-SoS). By doing so, the conflict that may arise while co-integrating new systems can be detected and solved in a shorter time. We propose the Smart Semantic Belief Function Clustered System of Systems (SSBFCSoS), which is an enhancement of the Ontology Belief Function System of Systems (OBFSoS). Results The proposed method proved the ability to rapidly detect and resolve conflicts. It showed the ability to accommodate more systems as well, therefore achieving the objectives of SoS. In order to test the applicability of the SSBFCSoS and compare its performance with other approaches, two datasets were employed. They are (Glest & StarCraft Brood War). With each dataset, 15 test cases were examined. We achieved, on average, 89% in solving the conflict compared to 77% for other approaches. Moreover, it showed an acceleration of up to proportionality over previous approaches for about 16% in solving conflicts as well. Besides, it reduced the frequency of the same conflicts by approximately 23% better than the other method, not only in the same cluster but even while combining different clusters.
Sparse regularization of a joint inversion of gravitational data and normal mode anomalies

To recover the density of the Earth we invert Newton's gravitational potential. It is a well-known fact that this problem is ill-posed. Thus, we need to develop a regularization method to solve it appropriately. We apply the idea of a Matching Pursuit (see Mallat and Zhang 1993) to recover a solution stepwise. At every step, the next expansion function and the corresponding weight are selected to best match the data structure. One big advantage of this method is that all kinds of different functions may be taken into account to improve the solution stepwise and, thus, the sparsity of the solution may be controlled directly. Moreover, this new approach generates models with a resolution that is adapted to the data density as well as the detail density of the solution. In the numerical part of this work, we reconstruct the density distribution of the Earth. For the area of South America, we perform an extensive case study to investigate the performance and behavior of the new algorithm. Furthermore, we research the mass transport in the area of the Amazon where the proposed method shows great potential for further ecological studies, i.e. to reconstruct the mass loss of Greenland or Antarctica. However, from gravitational data alone it is only possible to recover the harmonic part of the density. To get information about the anharmonic part as well, we need to be able to include other data types, e.g. seismic data in the form of normal mode anomalies. In this work, we will perform such an inversion and present a new model of the density distribution of the whole Earth. Zur Bestimmung der Dichte der Erde invertieren wir Newtons Gravitationspotential. Da dieses Problem bekanntlich schlecht gestellt ist, entwickeln wir ein geeignetes Regularisierungsverfahren um es zu losen. Wir wenden die Idee eines Matching Pursuits (siehe Mallat und Zhang 1993) an. Das heist, wir bestimmen, der Datenstruktur bestmoglich entsprechend, die Entwicklungsfunktion und den zugehorigen Koeffizienten schrittweise. Vorteilhaft ist, dass die unterschiedlichsten Funktionen zur Entwicklung der Losung beitragen konnen. Des weiteren erhalten wir Modelle, deren Auflosung an die Datendichte und die Detailstruktur der exakten Losung angepasst ist. Wir wenden die Methode auf die Rekonstruktion der Dichteverteilung der Erde (mit Erdinnerem) an. Fur das Gebiet um Sudamerika fuhren wir eine Fallstudie durch, in der wir die Gute und das Verhalten der Methode ausfuhrlich studieren. Des weiteren untersuchen wir den Massentransport im Amazonasgebiet. Die Ergebnisse lassen erwarten, dass die Methode auch fur andere okologisch relevante Problemstellungen, wie die Untersuchung des Massenverlustes in Gronland und der Antarktis, geeignet ist. Allerdings kann man aus Gravitationsdaten nur den harmonischen Anteil der Dichte rekonstruieren. Das Einbeziehen von seismischen Daten, wie Normal Mode Anomalies, erlaubt es, auch Informationen uber den anharmonischen Anteil zu erhalten. In der vorliegenden Arbeit wird das Ergebnis einer solchen Inversion als neues Modell fur die gesamte Erde vorgestellt.
Effect of In-vitro Gastrointestinal Digestion and Dialysis Process on Phenolic Compounds and Antioxidant Capacity of Selected Underutilized Fruits in Sri Lanka

The stability of phytochemicals and their inherent bioactivity may change after being subjected to gastro-intestinal digestion. This study investigated the bioactive potential of Elaeocarpus serratus, Pouteria campechiana, Annona squamosa and Annona muricata in terms of polyphenolic content and the antioxidant capacity. The in-vitro digestion process was carried out to quantify bioaccessible and bioavailable phytochemicals through each digestion phase analyzed by Folin-Ciocalteu method, DPPH radical scavenging assay and the total antioxidant capacity (TAC) of fruit extracts. The total phenolic contents (TPC) of the methanolic extracts of A. squamosa, E. serratus, A. muricata and P. campechiana were 718, 525, 370 and 306 μg gallic acid equivalents per g fresh weight (μg GAE per g FW), respectively. The highest absorption of phenolic compounds during the digestion was observed for P. campechiana as indicated by the TPC of the dialysis phase of extract (44.90 μg GAE per g FW) when compared with the initial TPC of fresh methanolic extract, which was the lowest of the fruits tested. The DPPH radical scavenging activity of fresh methanolic extracts of E. serratus (95.3%), A. squamosa (95.2%) and A. muricata (94.0%) showed a significantly higher percentage than P. campechiana (37.2%). The TPC, DPPH radical scavenging and TAC in the extracts of all digestion phases were lower, compared to their fresh methanolic extracts and may be attributed to the partial release or degradation of phenolic compounds during the digestion.
The evaluation of anti-NDV hyperimmune sera for serotherapy in chickens infected with Newcastle disease virus field isolate

A study was carried out at Faculty of Veterinary Medicine Udayana University from March 2018 to March 2020 to evaluate the possible use of anti-NDV hyperimmune sera (HIS) for immunotherapy in chickens infected with field ND virus. Hyperimmune sera (HIS) against NDV were used in this study with subcutaneous (SC) of HIS administrations. Four groups (I-IV) each consisted of 5 chickens were infected with NDV isolate. All chickens in groups I through III were treated with HIS at a dose of 1 mL per chicken whereas chickens of group IV were HIS-untreated. Chickens in group I was treated twice at 6 and 15 hours post infection (pi). Chickens of groups II were treated once at 48 h pi, whereas those in group III were treated twice at 48 h and 63 h pi. HIS treatments in ND chickens were able to prevent death and clinical symptoms especially when the treatment were given at 6 h and 15 h pi before the onset of clinical symptoms.
Adaptive Operating Hours for Improved Performance of Taxi Fleets

Taxi fleets and car aggregation systems are an important component of the urban public transportation system. Taxis and cars in taxi fleets and car aggregation systems (e.g., Uber) are dependent on a large number of self-controlled and profit-driven taxi drivers, which introduces inefficiencies in the system. There are two ways in which taxi fleet performance can be optimized: (i) Operational decision making: improve assignment of taxis/cars to customers, while accounting for future demand; (ii) strategic decision making: optimize operating hours of (taxi and car) drivers. Existing research has primarily focused on the operational decisions in (i) and we focus on the strategic decisions in (ii). We first model this complex real world decision making problem (with thousands of taxi drivers) as a multi-stage stochastic congestion game with a non dedicated set of agents (i.e., agents start operation at a random stage and exit the game after a fixed time), where there is a dynamic population of agents (constrained by the maximum number of drivers). We provide planning and learning methods for computing the ideal operating hours in such a game, so as to improve efficiency of the overall fleet. In our experimental results, we demonstrate that our planning based approach provides up to 16% improvement in revenue over existing method on a real world taxi dataset. The learning based approach further improves the performance and achieves up to 10% more revenue than the planning approach.
Epidemiologic Evidence for Association between a High Dietary Acid Load and the Breast Cancer Risk

Background and Purpose: Dietary acid load contributes to metabolic acidosis, leading to inflammation and cell transformation, potentially implicated in cancer development. Albeit an increased risk of recurrence among BC survivors was reported for a high acid load, the epidemiologic evidence associating diet-dependent acid load and cancer risk, particularly for breast cancer (BC), is still very limited. Therefore, we have explored in the present study its role in BC risk. Methods: A case-control study was performed on 1461 patients (572 BC cases and 889 age-frequency matched controls), through a multi-topic questionnaire, which included a food frequency questionnaire. Food-derived nutrients were calculated from available databases. The dietary acid load was calculated based on existing measures as potential renal acid load (PRAL) score and net endogenous acid production (NEAP) score. Odds Ratios (ORs) and their 95% confidence intervals were estimated by logistic regression, adjusting for potential confounders. Results: We found direct associations between dietary acid load and BC risk. Both scores were significantly associated (OR=2.46 and OR=1.78 for highest PRAL and NEAP, respectively). A positive BC family history involved higher risks (OR=6.14 and OR=3.38 for highest PRAL and NEAP, respectively). Linear trends were found in all overall and stratified analyses. Conclusions: Results suggest that a low acid load dietary style may reduce BC risk since both PRAL and NEAP scores were directly associated with meat intake and inversely associated with plant-based foods intake. The findings agree with studies focused on food groups and dietary patterns. Further studies are needed to confirm these findings.
Formation of hexamethylbenzene: chloranil charge transfer nanocrystals◊ Formación de nanocristales de transferencia de carga de hexametilbencen: cloranil

The nucleation and growth of nanoparticles can be induced using the reprecipitation method, in which a solution is rapidly mixed with a miscible non-solvent. This method has been used to create a wide variety of organic nanoparticles, including those comprised of polymers or of small molecules. Here we demonstrate the formation of charge transfer nanocrystals of the electron donor hexamethylbenzene and electron acceptor chloranil using the reprecipitation method. We achieve the rapid mixing needed for nanoparticle formation in a number of ways: using a 3D printed vortex micromixer, a double impinging jet mixer or direct jet injection of the solution into the non-solvent. The crystal formation kinetics are characterized over times scales from 10 ms to tens of minutes using UV-Vis absorption spectroscopy and dynamic light scattering.