Miracle-dz/UniFAR-FTUs huggingface dataset:
DIFFUSE X-RAY EMISSION FROM STAR-FORMING GALAXIES

We study the diffuse X-ray luminosity (LX) of star-forming galaxies using two-dimensional axisymmetric hydrodynamical simulations and analytical considerations of supernovae-(SNe-)driven galactic outflows. We find that the mass loading of the outflows, a crucial parameter for determining the X-ray luminosity, is constrained by the availability of gas in the central star-forming region, and a competition between cooling and expansion. We show that the allowed range of the mass loading factor can explain the observed scaling of LX with star formation rate (SFR) as L X ∝ ? > SFR2 for SFR ≳ 1 ? > M ⊙ ? > yr−1, and a flatter relation at low SFRs. We also show that the emission from the hot circumgalactic medium (CGM) in the halo of massive galaxies can explain the large scatter in the L X – SFR ? > relation for low SFRs (≲few M ⊙ ? > yr−1). Our results suggest that galaxies with small SFRs and large diffuse X-ray luminosities are excellent candidates for the detection of the elusive CGM.
WEYL CALCULUS AND DUAL PAIRS

We consider a dual pair (G,G ' ), in the sense of Howe, with G compact acting on L 2 (R n ) for an appropriate n via the Weil Representation. Let e G be the preimage of G in the metaplectic group. Given a genuine irreducible unitary representationof e G we compute the Weyl symbol of orthogonal projection onto L 2 (R n )�, the �-isotypic component. We apply the result to obtain an explicit formula for the character of the corresponding irreducible unitary representation � ' of e Gand to compute of the wave front set of � ' by elementary means.
Observational constraints on a unified dark matter and dark energy model based on generalized Chaplygin gas

We study a generalized version of Chaplygin gas as unified model of dark matter and dark energy. Using realistic theoretical models and the currently available observational data from the age of the universe, the expansion history based on the type Ia supernovae, the matter power spectrum, the cosmic microwave background radiation anisotropy power spectra, and the perturbation growth factor we put the unified model under observational test. As the model has only two free parameters in the flat Friedmann background [{Lambda}CDM (cold dark matter) model has only one free parameter] we show that the model is already tightly constrained by currently available observations. The only parameter space extremely close to the {Lambda}CDM model is allowed in this unified model.
Association Between Malignant Diseases and Medication-Related Osteonecrosis of the Jaw (MRONJ): A Systematic Review and Meta-Analysis

Purpose: The aim was to identify whether malignant diseases increase the risk of medication-related osteonecrosis of the jaw (MRONJ) occurrence when patients are exposed to bisphosphonate, antiresorptive or antiangiogenic drugs. To analyze related factors. Methods: A systematic literature searching was performed in PubMed, Embase, and Google Scholar for studies with information about whether patients have malignant diseases. Patients involved must be treated with MRONJ-related drugs and at high risk of developing MRONJ. Results: A total of 6 cohort studies and 3 case-control studies were included. Analysis according 9 studies shows that malignant diseases have significant influence on MRONJ occurrence (risk ratio (RR): 2.62; 95% confidence interval (95% CI): 1.58–4.33; P=0.0002). Subgroup analysis according 6 cohort studies also shows that malignant diseases significantly affect MRONJ occurrence (RR: 3.50; 95% CI: 1.63–7.52; P=0.001). Chemotherapy have no obvious influence on MRONJ occurrence (RR: 1.64; 95% CI: 0.79–3.39; P=0.18). Intravenous drug administration significantly influences MRONJ occurrence (RR: 2.67; 95% CI: 1.27–5.58; P=0.009). Conclusions: Patients with malignant diseases have higher risk of MRONJ occurrence when exposed to bisphosphonate, antiresorptive, or antiangiogenic drugs. Cumulative dosages from intravenous drugs administration contribute to MRONJ developing. Prevention of MRONJ in patients with malignancy should be emphasized.
MEASUREMENT OF A MAGNETIC FIELD IN A LEADING ARM HIGH-VELOCITY CLOUD

Using a recent catalog of extragalactic Faraday rotation derived from the NRAO VLA Sky Survey we have found an agreement between Faraday rotation structure and the H i emission structure of a high-velocity cloud (HVC) associated with the Leading Arm of the Magellanic System. We suggest that this morphological agreement is indicative of Faraday rotation through the HVC. Under this assumption we have used 48 rotation measures through the HVC, together with estimates of the electron column density from Hα measurements and QSO absorption lines to estimate a strength for the line-of-sight component of the coherent magnetic field in the HVC of 〈B∥〉 ≳ 6 μG. A coherent magnetic field of this strength is more than sufficient to dynamically stabilize the cloud against ram pressure stripping by the Milky Way halo and may also provide thermal insulation for the cold cloud. We estimate an upper limit to the ratio of random to coherent magnetic field of Br/B∥ < 0.8, which suggests that the random field does not dominate over the coherent field as it does in the Magellanic Clouds from which this HVC likely originates.
A Pilot Randomized Controlled Trial of an Online Educational Program for Primiparous Women to Improve Breastfeeding

Background: There are different approaches to breastfeeding interventions, but the global 6-month exclusive breastfeeding rates remain suboptimal. The COVID-19 pandemic has brought extra difficulties in promoting breastfeeding. Research Aim: To test the feasibility and effectiveness of a theory-based, real-time online educational and support program for breastfeeding related outcomes. Methods: An assessor-blinded, prospective pilot randomized controlled trial with parallel-group, repeated-measures design was used. The sample was low-risk primiparous mothers (N = 40) who delivered in the local public hospitals. Study outcomes consisted of exclusive breastfeeding rate, breastfeeding self-efficacy, and other breastfeeding outcomes measured by a self-reported questionnaire, including the Breastfeeding Self-Efficacy Scale and the Edinburgh Postnatal Depression Scale. Comparisons between the differences in the intervention and control groups were carried out. Results: Thirteen participants in the intervention group successfully completed the program. They had a higher exclusive breastfeeding rate, breastfeeding self-efficacy, breastfeeding initiation rate, and longer exclusive breastfeeding duration than the control group. Additionally, the intervention group had a lower partial breastfeeding rate, and a higher maternal postnatal depression score and infant’s morbidity at postnatal 2 months. However, all the results were not statistically significant (p > .050). Overall, the intervention was highly valued by all participants who appreciated the regular postnatal follow-ups. Conclusions: Despite showing the satisfactory feasibility of the program, no significant improvements were found in all study outcomes. Considering the participants’ comments, we suggest refining and further testing the intervention with a larger sample size over a longer-term follow-up to confirm its effectiveness. This study has been registered at ClinicalTrials.gov (NCT04741425)
The Relationship of Fear of Falling and Quality of Life: The Mediating Effects of Frailty and Depression

ABSTRACT Purpose To examine the sequential explanatory roles of frailty and depression in the relationship between fear of falling (FOF) and health-related quality of life (HRQoL) in older adults. Design Secondary data analysis Methods Path models were constructed hypothesizing frailty and depression as serial mediators of the relationship between FoF and HRQoL. Findings Depression independently and along with frailty serially mediated the relationship between FoF and mental HRQoL. Conclusions Frailty and depression are not typically considered when assessing the effect of FOF on HRQoL. Clinical Evidence Understanding the mediating effects and common risk factors on FOF and HRQoL may be an area for interventional development for older adults.
Normative database for Spaeth Richman contrast sensitivity test for Indian eyes

Purpose: To ascertain normative database of contrast sensitivity (CS) using Spaeth/Richman CS test (SPARCS) in the Indian population. Methods: This cross-sectional study enrolled 200 healthy individuals, and CS was tested in both eyes of each participant using SPARCS. A detailed ocular examination was done before enrollment to rule out pathologies that may affect CS. A practice test was performed in the right eye (OD), followed by uniocular testing in each eye and a final binocular test. Results: Data of 400 eyes of 200 subjects who fulfilled the inclusion criteria was evaluated. The average age of subjects was 46.57 ± 16.77 years (range 21–79 years), with a slight female preponderance (53%, n = 106). A statistically significant decline in average SPARCS scores was noted with increasing age (P < 0.05), ranging from 86.68 (20–29 years age group) to 67.44 (70–79 years age group). Higher scores were noted in binocular testing than uniocular testing (Interclass correlation coefficient [ICC] = 0.83; P < 0.001). Females achieved statistically significant higher total scores in uniocular SPARCS testing (both OD and OS), but there was no significant difference noted between the two genders in binocular testing. Correlation between practice and main tests was statistically Significant with an interclass correlation coefficient of 0.54 (P < 0.001). Conclusion: Normative database for SPARCS was established for Indian eyes, with a decreasing trend noted in peripheral as well as central CS scores with increasing age.
Mass Formulas Derived by Symmetry Breaking and Prediction of Masses on Heavy Flavor Hadrons

The base is the Lagrangian of symmetry and its dynamical breaking or Higgs breaking. When the soliton-like solutions of the scalar field equations are substituted into the spinor field equations, in the approximation of non-relativity we derive the Morse-type potential, whose energy spectrum is the GMO mass formula and its modified accurate mass formula. According to the symmetry of s-c quarks, the heavy flavor hadrons which made of u,d and c quarks may be classified by SU(3) octet and decuplet. Then some simple mass formulas are obtained, from this we predict some masses of unknown hadrons.
Contribution of cyclooxygenase-2 overexpression to enhancement in tonically active glutamatergic inputs to the rostral ventrolateral medulla in hypertension

Objective: Cyclooxygenase (COX) is critical in regulating cardiovascular function, but its role involved in the central control of blood pressure (BP) is uncovered. The tonic glutamatergic inputs to the rostral ventrolateral medulla (RVLM) are enhanced in hypertension. Here, the present study was designed to investigate the effect and mechanism of central COX on tonic glutamatergic inputs to the RVLM and BP regulation. Methods: Wistar-Kyoto (WKY) rats and spontaneous hypertensive rats (SHRs) received RVLM microinjection of adeno-associated viral vectors to promote or inhibit the COX2 expression were subjected to subsequent experiments. Glutamate level and glutaminase expression were detected by ELISA and western blot, respectively. The function of tonic glutamatergic inputs was assessed by BP response to microinjection of the glutamate receptor antagonist into the RVLM. PC12 cells were used to detect the underlying signal pathway. Results: The RVLM COX2 expression and prostaglandin E2 level were significant higher in SHRs than in WKY rats. Overexpression of COX2 in the RVLM produced an increase in basal BP, RVLM glutamate level, and glutaminase expression in WKY rats, while they were significantly reduced by interfering with COX2 expression in SHRs. Microinjections of the glutamate receptor antagonist into the RVLM produced a significant BP decrease in WKY rats with COX2 overexpression pretreatment. Furthermore, the increased levels of BP, glutamate content, and glutaminase activity in the RVLM evoked by central infusion of angiotensin II were attenuated in COX2 knockout mice. It was also found that prostaglandin E2 increased supernatant glutamate level and phosphorylation of signal transducer and activator of transcription 3 in PC12 cells. Conclusion: Our findings suggest that upregulated COX2 expression enhances the tonically active glutamatergic inputs to the RVLM, which is associated with cardiovascular regulation in hypertension.
AN EXTREME GRAVITATIONALLY REDSHIFTED IRON LINE AT 4.8 KeV IN Mrk 876

X-ray spectral lines at unforeseen energies are important because they can shed light on the extreme physical conditions of the environment around the supermassive black holes of active galactic nuclei (AGNs). Mrk 876 displays such a line at rest-frame energy. A possible interpretation of its origin can be found in the hotspot scenario. In this scenario, the primary radiation from a flare in the hot corona of an AGN illuminates a limited portion of the accretion disk that emits by fluorescence. In this context, the line can represent an extreme gravitationally redshifted Fe line originating on the accretion disk below six gravitational radii from a rotating supermassive black hole. The correct estimate of the line significance requires a dedicated approach. Based on an existing rigorous approach, we have performed extensive Monte Carlo simulations. We determine that the line is a real feature at a ∼99% confidence level.
Real world experience of brodalumab treatment in patients with moderate‐to‐severe plaque psoriasis in the Greek population: Results from an interim analysis of the BrIDGE study

Brodalumab's clinical efficacy and favorable safety profile have been demonstrated during controlled clinical trials, but real‐world data remain scarce. BrIDGE, an ongoing 104 week, observational, prospective, multicenter study conducted in Greece, enrolled moderate‐to‐severe plaque psoriasis patients, with body surface area (BSA) > 10 or psoriasis area severity index score (PASI) > 10 and dermatology life quality index (DLQI) > 10, based on European consensus, initiating brodalumab treatment as per routine clinical practice. This interim analysis includes evaluations 12–16 weeks following treatment initiation. Key efficacy endpoints included proportion of patients achieving static Physician's Global Assessment (sPGA) score of “clear/almost clear” (0/1) and a reduction ≥75%, 90%, 100% from baseline in PASI (PASI75, PASI90, and PASI100) at weeks 12–16. Other endpoints included time to achieve PASI100, changes in self‐reported DLQI and psoriasis symptom inventory (PSI) at weeks 12–16. From 200 patients (mean age 51.4 years, 70% male, mean disease duration 13.8 years) enrolled, 72.8% achieved sPGA of 0/1, whereas 70.2%, 47.5%, and 32.0% achieved corresponding PASI75, PASI90, and PASI100 responses following 12–16 weeks of brodalumab treatment, according to the “as‐observed” analysis. The mean time to achieve PASI100 was 13.7 ± 1.2 weeks for the 32% who achieved PASI100. Concurrent decreases in mean DLQI and PSI were observed. Furthermore, 90% adherence to brodalumab was noted and nine adverse events were reported. Brodalumab confers substantial clinical improvements short‐term as reflected by high levels of skin clearance in moderate‐to‐severe plaque psoriasis patients within 12–16 weeks of treatment under everyday clinical conditions, followed by improvements in symptoms and quality of life and a favorable safety profile.
NIBLES – an HI census of stellar mass selected SDSS galaxies - II. Arecibo follow-up HI observations

We obtained Arecibo Hi line follow-up observations of 154 of the 2600 galaxies in the Nancay Interstellar Baryons Legacy Extragalactic Survey (NIBLES) sample. These observations are on average four times more sensitive than the original observations at the Nancay Radio Telescope. The main goal of this survey is to characterize the underlying Hi properties of the NIBLES galaxies which were undetected or marginally detected at Nancay. Of the Nancay non-detections, 85% were either clearly or marginally detected at Arecibo, while 89% of the Nancay marginal detections were clearly detected. Based on the statistics of the detections relative to g − i color and r -band luminosity ( L r ) distribution among our Arecibo observations, we anticipate ~60% of our 867 Nancay non-detections and marginal detections could be detected at the sensitivity of our Arecibo observations. Follow-up observations of our low luminosity ( L r 8.5 L ⊙ ) blue sources indicate that they have, on average, more concentrated stellar mass distributions than the Nancay detections in the same luminosity range, suggesting we may be probing galaxies with intrinsically different properties. These follow-up observations enable us to probe Hi mass fractions, log( M HI / M ⋆ ) 0.5 dex and 1 dex lower, on average, than the NIBLES and ALFALFA surveys respectively.
Characterization of neurobehavioral pattern in a zebrafish 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced model: A 96-hour behavioral study

Parkinson’s disease (PD) is the most common brain motor disorder, characterized by a substantial loss of dopaminergic neurons in the substantia nigra pars compacta (SNpc). Motor impairments, such as dyskinesia, bradykinesia, and resting tremors, are the hallmarks of PD. Despite ongoing research, the exact PD pathogenesis remains elusive due to the disease intricacy and difficulty in conducting human studies. Zebrafish (Danio rerio) has emerged as an ideal model for researching PD pathophysiology. Even though 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) has been used to induce PD in zebrafish, behavioural findings are frequently limited to a single time point (24 hours post-injection). In this sense, we aim to demonstrate the effects of MPTP on zebrafish swimming behaviour at multiple time points. We administered a single dosage of MPTP (200μg/g bw) via intraperitoneal injection (i/p) and assessed the locomotor activity and swimming pattern at 0h, 24h, and 96h post-injection through an open field test. Analysis of the behaviour revealed significant reductions in swimming velocity (cm/s) and distance travelled (cm), concurrent with an increase in freezing maintenance (duration and bouts) in zebrafish injected with MPTP. In addition, the MPTP-injected zebrafish exhibited complex swimming patterns, as measured by the turn angle, meander, and angular velocity, and showed abnormal swimming phenotypes, including freezing, looping, and erratic movement. To conclude, MPTP administration into adult zebrafish induced hypolocomotion and elicited motor incoordination. Plus, the effects of MPTP were observable 24 hours after the injection and still detectable 96 hours later. These findings contribute to the understanding of MPTP effects on adult zebrafish, particularly in terms of swimming behaviours, and may pave the way for a better understanding of the establishment of PD animal models in the future.
Norepinephrine Innervation of the Supraoptic Nucleus Contributes to Increased Copeptin and Dilutional Hyponatremia in Male Rats.

Dilutional hyponatremia associated with liver cirrhosis is due to inappropriate release of arginine vasopressin (AVP). Elevated plasma AVP causes water retention resulting in a decrease in plasma osmolality. Cirrhosis, in this study caused by ligation of the common bile duct (BDL), leads to a decrease in central vascular blood volume and hypotension, stimuli for non-osmotic AVP release. The A1/A2 neurons stimulate the release of AVP from the supraoptic nucleus (SON) in response to non-osmotic stimuli. We hypothesize that the A1/A2 noradrenergic neurons support chronic release of AVP in cirrhosis leading to dilutional hyponatremia. Adult, male rats were anesthetized with 2-3% isoflurane (mixed with 95% O2/5% CO2) and injected in the SON with anti-DBH saporin (DSAP) or vehicle followed by either BDL or sham surgery. Plasma copeptin, osmolality, and hematocrit were measured. Brains were processed for delta FosB, dopamine β-hydroxylase (DBH) and AVP immunohistochemistry. DSAP injection: i) significantly reduced the number of DBH immunoreactive A1/A2 neurons (A1, P<0.0001; A2, P=0.0014), ii) significantly reduced the number of A1/A2 neurons immunoreactive to both DBH and delta FosB positive neurons (A1, P=0.0015; A2, P<0.0001), iii) reduced the number of SON neurons immunoreactive to both AVP and delta FosB (P<0.0001), iv) prevented the increase in plasma copeptin observed in vehicle injected BDL rats (P=0.0011) and v) normalized plasma osmolality and hematocrit (plasma osmolality, P =0.0475; hematocrit, P = 0.0051) as compared to vehicle injection. Our data suggest that A1/A2 neurons contribute to increased plasma copeptin and hypoosmolality in male BDL rats.
STRUCTURAL PARAMETERS OF GALAXIES IN CANDELS

We present global structural parameter measurements of 109,533 unique, HF160W-selected objects from the CANDELS multi-cycle treasury program. Sérsic model fits for these objects are produced with GALFIT in all available near-infrared filters (HF160W, JF125W and, for a subset, YF105W). The parameters of the best-fitting Sérsic models (total magnitude, half-light radius, Sérsic index, axis ratio, and position angle) are made public, along with newly constructed point-spread functions for each field and filter. Random uncertainties in the measured parameters are estimated for each individual object based on a comparison between multiple, independent measurements of the same set of objects. To quantify systematic uncertainties, we create a mosaic with simulated galaxy images with a realistic distribution of input parameters and then process and analyze the mosaic in an identical manner as the real data. We find that accurate and precise measurements—to 10% or better—of all structural parameters can typically be obtained for galaxies with HF160W < 23, with comparable fidelity for basic size and shape measurements for galaxies to HF160W ∼ 24.5.
Renewable Energy Consumption-Growth Nexus in European Countries: A Sectoral Approach

The renewable energy consumption plays a significant role in achieving sustainable development, but a sectoral approach is necessary to design the better recommendations for each sector. In this context, the main objective of this paper is to assess the impact of the use of this type of energy on economic growth in 23 European Union (EU) member states in the period 1990–2020. Besides overall renewable energy consumption, different utilisations of this energy are considered: in industry, transport, in commercial and public services, and for residential purposes. The methodological background is built around panel data models that start from a Cobb–Douglas function. The renewable energy consumption is considered an important factor that should generate economic growth. The panel data approach based on causality analysis and Augmented Mean Group and Common Correlated Effects Mean Group estimators suggests that renewable energy use in industry does not determine economic growth, but economic development is a cause for more utilisation of this energy in industry. In addition, more renewable energy consumption in transport enhances economic growth. A high level of economic development can promote the consumption of renewable energies in industrial sectors. In this way, industrial companies can allocate more financial funds to research in the field of renewable energies and can afford to adopt renewable energy sources. Investment in biofuels can contribute to achieving sustainable transport in the EU.