Miracle-dz/UniFAR-FTUs huggingface dataset:
On the Stability of the Hadley Flow under the Action of an Acoustic Wave

The effects of an acoustic wave on the in- stabilities occurring in a lateral differentially heated cav- ity are investigated numerically. Linear stability results show that the acoustic wave affects significantly the in- stability characteristics of such a Hadley flow. Indeed, the soundfield is found to stabilizeboth two dimensional transverse stationary and three dimensional longitudinal oscillatoryinstabilitieswhich are the most critical modes affecting the buoyant convection in the fluid layer. Nev- ertheless, when stabilized by an acoustic wave, the 2D modes turn fromstationaryto oscillatory,withtheknown consequences of such a change on mass and heat trans- fer, especiallyinhorizontalBridgmancrystalgrowthpro- cess. Thesecondfeaturetobementionedisthatthelinear stabilitypredictsadestabilizationof3Dstationarymodes that in the absence of acousticwaves are known to be ex- cited at threshold values of the Grashof number highly above those of the two primary instabilities.
Exploring the effects of electorate size on indigenous voter turnout

ABSTRACT A growing body of scholarship suggests that Indigenous peoples abstain from voting in national and subnational elections because of colonialism and so classic determinants of turnout do not apply. We investigate this argument by examining the relationship between electorate size and voter turnout in federal, provincial and regional elections in five Inuit communities in Canada, leveraging the fact that these communities are mostly similar across a range of factors. Given that these communities negotiated and established their own regional government in 2005 and given the colonial and settler nature of the federal and provincial governments, we expect classic determinants of turnout, such as electorate size, to apply only at the regional level. Surprisingly, however, we find that electorate size influences turnout at the federal and regional levels but not at the provincial level.
Estabilidad temporal y validez discriminante del Inventario de Ansiedad de Beck

Background: Anxiety disorders are the most prevalent worldwide, followed by depressive disorders. The Beck Anxiety Inventory (BAI; Beck et al., 1988) has been developed to assess the severity of anxiety symptoms and perform a differential diagnosis between anxiety and depression disorders. Objective: To examine the temporal stability of the BAI in its version adapted to Argentina and obtain evidence of discriminant validity. Method: In a sample of 52 people, the intraclass correlation coefficient was analyzed. Then, in a sample of 225 people, a correlation analysis between BAI scores and the Beck Depression Inventory-II (BDI-II; Beck et al., 2006) was performed; subsequently, an exploratory factor analysis (EFA) with reagents from both instruments was conducted and the heterotrait-monotrait ratio of correlations (HTMT) was calculated. Results: The intraclass correlation coefficient was . 82 (95% CI = .69 - .90). The correlation between the BAI and the BDI was . 56 (moderate effect size). The EFA showed two well-differentiated factors and an HTMT proportion value of . 66 (95% CI = .55 - .74) was found. Conclusions: An adequate temporal stability is observed and evidence of the discriminant validity of the instrument is provided.
Political Epistemology and Social Critique

Under conditions of ideology, a standard model of normative political epistemology—relying on a domain-specific reflective equilibrium—risks status-quo bias. Social critique requires a more critical standpoint. What are the aims of social critique? How is such a standpoint achieved and what grounds its claims? One way of achieving a critical standpoint is through consciousness raising. Consciousness raising offers a paradigm shift in our understanding of the social world; but not all epistemic practices that appear to “raise” consciousness are warranted. However, under certain conditions sketched in the chapter, consciousness raising produces a warranted critical standpoint and a pro tanto claim against others. This is an important epistemic achievement, yet under conditions of collective self-governance, there is no guarantee that all warranted claims can be met simultaneously. There will be winners and losers even after legitimate democratic processes have been followed.
Evaluation of Cement-Casing & Cement-Rock Bond Integrity During Well Operations

This paper presents the results of laboratory static and dynamic tests on casing-cement-rock systems exposed to axial loads under ambient conditions. A new testing method has been developed. The casing-cement-rock system mostly fails due to tension and shear stresses. In various applications such as HPHT, deep-water, (steam) injection or geothermal wells, the cement-casing bond is exposed to cyclic thermomechanical loads resulting in casing elongation, contraction, expansion and subsequently in cyclic radial and axial stresses at the cement-casing-rock system. Cement is a brittle material which can fail when subjected to repeated application of stresses lesser in magnitude than the statically determined strength. A novel atmospheric test cell has been designed and constructed. In order to achieve the fatigue limits of the cement-casing bond, a set of testing procedures has been established. Several tests are conducted to evaluate de-bonding. The focus on de-bonding is achieved by allowing the casing to move through the test while preventing any cement movement. Thus, when a force is applied in the axial z-direction - either the casing is pulled out (tension) or pushed down (compression) - the casing has enough space to move in both directions. The advantage of this testing method is that different stress ratios can be applied during the test.
Anaphoricity in emoji: An experimental investigation of face and non-face emoji

Emoji are widely used, but have received relatively little attention in psycholinguistic research. Upon encountering a message consisting of both text and emoji, readers presumably construct some link between emoji and text. Based on a psycholinguistic study on text-emoji relations, we argue for (at least) two types of emoji-text dependencies, related to referential dependencies known to exist in the linguistic domain, namely (i) the dependency between an expressive (e.g. wow, damn, f*king ) and the individual whose opinion it expresses, and (ii) the dependency between a pronoun (or other pro-form) and its antecedent. We extend the discussion of these dependencies to emoji, and provide experimental data that face emoji resemble expressives in that they tend to be interpreted as expressing the opinion of a salient experiencer, while action emoji are interpreted based on principles of discourse coherence (e.g. discourse relations like explanation), similar to what coherence-based accounts of pronoun resolution predict.
Experimental Study on Earthquake Resilience of Low-Damage Self-Centering Precast Concrete Frame Connections

ABSTRACT The earthquake resilience of low-damage self-centering precast concrete frame connections (LDSCPC) is studied in this article. Cyclic load tests are carried out, and the results show that the overall damage of the precast beam of specimen LDSCPC1 at 3% drift is even less than that of specimen RC1 at 0.25% drift. The LDSCPC connections can still maintain the original performance to a large extent after the earthquake and almost wholly recover to the initial performance level after replacing the dampers. Based on maintaining similar bearing capacity and deformation ability with RC joint, LDSCPC connections have excellent earthquake resilience.
Link Recommendation for Social Influence Maximization

Social link recommendation systems, like “People-you-may-know” on Facebook, “Who-to-follow” on Twitter, and “Suggested-Accounts” on Instagram assist the users of a social network in establishing new connections with other users. While these systems are becoming more and more important in the growth of social media, they tend to increase the popularity of users that are already popular. Indeed, since link recommenders aim to predict user behavior, they accelerate the creation of links that are likely to be created in the future and, consequently, reinforce social bias by suggesting few (popular) users, giving few chances to most users to create new connections and increase their popularity. In this article, we measure the popularity of a user by means of her social influence, which is her capability to influence other users’ opinions, and we propose a link recommendation algorithm that evaluates the links to suggest according to their increment in social influence instead of their likelihood of being created. In detail, we give a factor approximation algorithm for the problem of maximizing the social influence of a given set of target users by suggesting a fixed number of new connections considering the Linear Threshold model as model for diffusion. We experimentally show that, with few new links and small computational time, our algorithm is able to increase by far the social influence of the target users. We compare our algorithm with several baselines and show that it is the most effective one in terms of increased influence.
Systemic immune microenvironment and regulatory network analysis in patients with lung adenocarcinoma

Background This study applied a complex bioinformatics analysis to explore the hub regulators and immune network to further elucidate the molecular mechanisms of lung adenocarcinoma (LUAD) immune regulation. Methods LUAD immunological microenvironment features and microenvironment-related differential expression genes (DEGs) were identified by ESTIMATE algorithm and linear models for microarray analyses (LIMMA), respectively. CIBERSORT and Igraph algorithms were applied to construct the LUAD-related immunocyte infiltration and regulatory network. Kaplan-Meier survival analysis, and univariate and multivariate Cox analysis were used to predict independent risk factors and screen for the hub genes. In addition, hub genes-correlated gene set enrichment analysis (GSEA), tumor mutation burden (TMB), and clinic pathological relation analyses were also performed. Results Stromal, immune, and microenvironment comprehensive features (ESTIMATE score) were associated with overall survival (OS) in LUAD patients (all, P<0.05). T-cell activation, chemokine activity, and immune effect or dysfunction gene ontology maps were associated with the LUAD immune microenvironment. The immune infiltration cell subtypes mast cells (masT-cells) resting [The Cancer Genome Atlas (TCGA): P=0.01; Gene Expression Omnibus (GEO): P=1.79e−05] and activated T-cells (CD4 memory) (TCGA: P<0.01; GEO: P=8.52e−05) were found to have an important role in the immune cell regulatory network. Finally, ITGAL [univariate hazard ratio (HR) =0.80, 95% confidence interval (CI): 0.69–0.93, P<0.01; multivariate HR =0.59, 95% CI: 0.40–0.86, P=0.01] and KLRB1 (univariate HR =0.78, 95% CI: 0.69–0.89, P<0.01; multivariate HR =0.72, 95% CI: 0.58–0.90, P<0.01) were correlated with the T-cell receptor signaling pathway and anaplastic lymphoma kinase (ALK) fusion (ITGAL: P=0.034; KLRB1: P=0.050), and were considered as candidate biomarkers. A significant relation between KLRB1 expression level and TMB (P=3.6e−05) was identified, while no relation was detected for ITGAL (P=0.11). Conclusions The T-cell activation and activated T-cell (CD4 memory) pathways were predominantly involved in LUAD immune microenvironment regulation. The expression levels of ITGAL and KLRB1 were significantly correlated with the T-cell receptor signaling pathway and LUAD TMB, and were independent risk factors for OS.
BIOMARKER CANDIDATES IDENTIFIED IN BEHCET’S DISEASE USING INTEGRATIVE ANALYSIS

: Behcet’s Disease is a rare auto inflammatory and autoimmune disorder that causes blood vessel inflammation throughout the body and can affect all organ systems. The pathophysiology of the disease is still under investigation. Since the symptoms are varying it is difficult to diagnose and there are no sufficient medical treatments for the disease. In this study Behcet’s Disease gene (Samples from isolated CD4+ T cells and CD14+ monocytes) and miRNA expression (samples from platelet free plasma) datasets were statistically analyzed. Differentially expressed genes for CD4+ T cells and CD14+ monocytes have been identified and miRNA associated with this data were listed. Protein-protein and miRNA – target gene interaction networks were constructed and hubs of these networks were identified for both cell types. Metabolites and metabolic pathways associated with gene expression data were displayed and enrichment analysis was done to identify associated signaling pathways and diseases. Differentially expressed miRNAs of platelet free plasma samples were also identified. The analysis results indicated cell/tissue type dependent genomic reprogramming. Mutual hub miRNAs (hsa-miR-17-5p, hsa-miR-603, hsa-miR-375, hsa-miR-107, hsa-miR-454-3p, hsa-miR-650, hsa-miR-142-3p and hsa-miR-765) in all cell/tissue types and metabolites (guanidinoacetate and histone-L-lysine) for CD4+ and CD14+ cells may be considered as biomarker candidates. Future studies focusing on these candidate biomarkers might yield a diagnostic kit or design of enhanced therapeutics for Behcet’s Disease.
Genetic structure and gene flow in the Flame Robin (Petroica phoenicea)

ABSTRACT Robins in the family Petroicidae are characteristic of the woodland bird community that is threatened in Australia as a result of habitat loss and fragmentation. Flame Robin (Petroica phoenicea) populations declined by 56% between 1980 and 2000, with habitat loss likely being the primary cause. Given that Flame Robins primarily breed at high elevation, populations may become more isolated due to anthropogenic change, resulting in increased inbreeding and loss of genetic diversity that may accelerate local extinction. We estimated the genetic structure and recent gene flow among four populations (n = 70 birds) of this vulnerable (NSWSC) species across a 670 km portion of its range in temperate south-eastern Australia using 14 genetic markers. We found no significant differences in genetic diversity amongst populations and little population structuring – only the northernmost population showing a weak signal of differentiation. However, we detected little recent migration between the northern and southern sites, possibly due to recent fragmentation. We conclude that habitat loss is a conservation concern for this Vulnerable species and further work and ongoing genetic monitoring is needed, particularly given high elevation breeding sites that are vulnerable in the face of a changing climate.
Remote e-Workers’ Psychological Well-being and Career Development in the Era of COVID-19: Challenges, Success Factors, and the Roles of HRD Professionals

The Problem As most employees have been forced to work from home during the COVID-19 pandemic, there is considerable concern about how to preserve employee health and well-being by supporting their work in this unpredictable situation. In this sense, research highlighting how to support remote e-workers in the COVID-19 pandemic era is urgently needed to inform scholars and practitioners about effective strategies and interventions to support remote e-workers. The Solution By reviewing conceptual and empirical studies, we discuss the challenges of remote e-workers from the perspective of psychological well-being. We also summarize the factors that support psychological well-being. Based on the findings, we suggest how human resource development (HRD) professionals can support remote e-workers’ psychological well-being and career development in the COVID-19 pandemic era. The Stakeholders This article has relevance for scholars, scholar-practitioners, and practitioners who are interested in seeking ways to support remote e-workers from an HRD perspective across countries, disciplines, and contexts in the COVID-19 pandemic era.
The discovery of small-molecule inhibitors of Keap1-Nrf2 interaction with homogeneous fluorescence-based high throughput screening assays

OF THE DISSERTATION.ii ACKNOWLEDGEMENTS.iv DEDICATION.v TABLE OF CONTENTS.vi LIST OF TABLES.viii LIST OF FIGURES.ix LIST OF SCHEMES.xii ABBREVIATIONS.xiv CHAPTER ONE.
The effect of gradual addition of camelina seeds in the diet of rainbow trout (
 Oncorhynchus mykiss
 ) on growth, feed efficiency and meat quality

Camelina ( Camelina sativa ) is a robust crop to cultivate and a potential source of protein, oil and n- 3 fatty acids for aquaculture. The aim of this study was to examine the effects of camelina seed in feed on rainbow trout ( Oncorhynchus mykiss ) performance and nutritional composition of the muscle. A mixture of faba bean, wheat gluten meal and rapeseed oil was gradually replaced by camelina seed (0%, 10% and 20% camelina in the diet). Fifty 0+ old fish were placed in each of the 12 recirculation aquaculture tanks to enable three treatments with four replicates. Camelina seed inclusion did not affect the growth performance, crude protein or fat content of fish body. The moisture content was the lowest ( p = 0.021) with 20% camelina. The vitamin D 3 contents in fish muscle were low, indicating that camelina may slightly impair the absorption of vitamin D 3 ( p = 0.055). Camelina diets decreased ( p < 0.001) the proportion of monounsaturated fatty acids and increased ( p < 0.001) polyunsaturated fatty acids and n- 3 fatty acids, particularly α - linolenic acid, in fish muscle. Camelina seed proved to be a potential plant- based ingredient for rainbow trout feed.
Maternal/Child Social Support and Food Security in Relation to Child Height and Bmi in Four Low- and Middle- Income Countries: Mediation Analysis of Young Lives Data

BackgroundPoor nutritional status in childhood is associated with an elevated risk of mortality and morbidity later in life. Previous studies showed a positive association between specific types of social capital and child nutritional status. Our study examined whether improved food security mediates the impact of maternal and child social support on child height and body mass index (BMI) in four low- and middle-income countries.Methods We used data from the Young Lives cohort study comprising roughly 1,000 children at age 8 and 12 in Vietnam, Ethiopia, India, and Peru. Outcome variables were z-score for height (HAZ) and BMI (BAZ). Results Belonging to the top half of maternal financial support and child financial support was positively associated with child HAZ at age 12 in Peru. Belonging to top half of overall maternal support among children aged 8 in Vietnam, and maternal financial support among children aged 12 in India were also positively associated with child BAZ. A positive association of food security was only found with maternal financial support among children aged 12 in Peru. However, food security did not play a significant role in mediating the effect of maternal financial support on child HAZ at age 12. ConclusionsStrengthening social support to improve child nutritional status may not be a sufficient intervention in resource-poor settings because sources of supports may lack sufficient food resources to share. Considering between-country heterogeneity, a “one size fits all” approach for enhancing social capital may not be appropriate.
Biofilm Production by Food-Transmitted Bacteria and Their Control by Selected Nanoparticles

Biofilm is a population of bacteria attached to any types of surfaces and impeded in a self-produced matrix of extracellular polymeric substances. Biofilm exhibit up to 1000 fold antibiotic increased resistance to a broad range of antimicrobial agents. Several food-transmitted microorganisms are capable of forming biofilms and considered as a major source of contamination, transmission and infection. In the last few decades, nanoparticles has gained a great attention for their potential applications as antimicrobial agents. The aim of this work was to assess the biofilm formation capacity of food-transmitted bacteria under various environmental conditions and to investigate the efficacy of different nanoparticles (i.e. Ag-Cu-B, Ag-Na-B, and Ag-Mg-B) to kill microbial pathogens in biofilms. Nanoparticles were synthesized by using co-precipitation and microwave techniques and characterized for their physiochemical properties by transmission electron microscopy and light dynamic scattering. The antibiofilm and antimicrobial properties of the synthesized nanoparticles were investigated using S. aureus (10 strains), P. aeruginosa and E. coli (3strains). The findings revealed that all NPs significantly inhibited planktonic cells and biomass of the grown biofilms. Moreover, the sanitization efficacy of nanoparticles were assessed on stainless steel surface that commonly come into contact with food. The surfaces were inoculated with strains of S. aureus and Salmonella and cleaned with NPs saturated sanitary wipes. A significant reduction was observed in viability of the cells on the stainless steel surfaces. The results demonstrated that the use of NPs incorporated into sanitary wipes is useful method to eliminate bacteria on food contact surfaces.
The Emotional Foundations of Political Support: How Fear and Anger Affect Trust in the Government in Times of the Covid‐19 Pandemic

Abstract Crises like the current coronavirus pandemic evoke negative emotions in the general public. To date, however, little research has been conducted on the influence of these mental states on trust in the government – the uncontested key player in times of crises. Drawing on the appraisal and affective intelligence theories of emotions, we argue that fear and anger as the two crucial negative emotions in times of crises have divergent effects on trust in the government: Whereas fear leads to a rally‐‘round‐the‐flag effect increasing trust in the government, anger attributes blame for the adverse circumstances to the government. We present empirical evidence for our arguments with an original three‐wave online panel survey of 1’600 Swiss residents during the unprecedented times of the coronavirus pandemic. Our analysis provides empirical support for our arguments and further shows that the relationship is strongest for right‐wing respondents.