Miracle-dz/UniFAR-FTUs huggingface dataset:
Optical frequency domain imaging with a rapidly swept laser in the 1300nm bio-imaging window

Optical frequency domain imaging system (OFDI) in the 1300nm biological imaging window is demonstrated by using a high speed frequency swept laser source. The output of the laser with central wave length of 1320nm is continuously tuned over a bandwidth of 100nm with a repetition rate of 16 KHz. The laser source has an instantaneous coherence length of 6mm and delivers an average power of 12mW. Axial resolution ~ 6μm in the biological tissue and peak sensitivity of 110dB are achieved. The experimentally determined values of the imaging parameters such as the axial resolution, sensitivity and depth range are found to be in good agreement with the theoretically estimated values. The developed system is capable of generating the images of size 512x1024 at a rate of 20 frames per second. High resolution and high contrast images of the finger nail and anterior chamber of a pig’s eye acquired using the developed OFDI system are presented, which demonstrate the feasibility of the system for in-vivo biomedical imaging applications.
AVOGADRO: il CILEA oltre il muro del TeraFlops

Il CILEA, in collaborazione con le Universita di Milano, Milano Bicocca, e Politecnico di Milano, potenzia il suo parco macchine per il calcolo parallelo ad alte prestazioni con un cluster di 128 nodi biprocessori Intel Xeon 3.06GHz, fornito dalla Exadron, Divisione High Performance Computing di Eurotech Spa. Con questa acquisizione il CILEA diversifica la sua offerta e si conferma tra le piu importanti realta del supercalcolo europeo.
Social Media Listening in the COVID-19  Environment by Song He and Emre Erturk

Companies are constantly engaged in the arena of social media, whereby any posts, comments, sentiments, and even clicks can make an impact on the market and their brands. Being able to quickly sense the social media sentiment and give prompt responses is a crucial task. This paper originally conducted a case study to explore social listening, which is a useful social media strategy. The aim was to demonstrate feasible social listening strategies and practices. In the ﬁrst part of the paper, the idea of social listening and the ways of measurement are described. Here the paper used a case study approach. By leveraging a social listening tool called SentiOne, a New Zealand Brand (Pak’nSave was studied under diﬀerent business scenarios. The involved looking at the brand image, competition
The Influence of Service Quality and Price on the Interest of Commuterline KRL Passengers

This electric train transportation facility is a means of transportation that avoids traffic congestion because it has its own route. Transportation competition can be seen through aspects of service quality to transportation service providers. The excellence of the company can be demonstrated by providing good quality service and striving for affordable ticket prices by the public. This study aims to determine and analyze the effect of Service Quality and Prices on Commuterline KRL Passenger Interest. This study used 125 respondents who used the commuterline train at Tanjung Priok station. This study used a quantitative method with multiple linear regression analysis taking data by distributing questionnaires. Sampling in this study using nonprobability sampling techniques. The results of the analysis partially and simultaneously show that service quality and price affect the interests of passengers.
Control of Articulated Robot Arm by Eye Tracking

Eye tracking has many comprehensive achievements in the field of human computer interaction. Uses of human eyes as an alternative of hands are an innovative way in the human computer interaction perspective. Many application of autonomous robot control has already been developed, but we developed two different interfaces to control the articulated robot manually. The first of these interfaces is controlled by mouse and the second is controlled by eye tracking. Main focus of our thesis is to facilitate the people with motor disabilities by using their eye as an input instead of a mouse. Eye gaze tracking technique is used to send commands to perform different tasks. Interfaces are divided into different active and inactive regions. Dwell time is a well known technique which is used to execute commands through eye gaze instead of using a mouse. When a user gazes in an active region for a specific dwell time, the command is executed and the robot performs a specific task. When inactive regions are gazed at, there no command execution and no function are performed. The difference between time of performing the task by mouse and Eyetracking is shown to be 40 ms, the mouse being faster. However, a mouse cannot be used for people with motor disabilities, so the Eyetracker in this case has a decisive advantage. Keywords: Eyetracking, Interface, Articulated robot
Multiregion sequencing reveals the genetic correlation of esophageal squamous cell carcinoma and matched cell-free DNA

Background: The aim of this study was to assess whether both ubiquitous and heterogeneous somatic mutations could be detected in circulating cell-free DNA (cfDNA) from patients with esophageal squamous cell carcinoma (ESCC). Methods: Paired multi-regional tumor tissues, cfDNA and white blood cells (WBCs) collected from five ESCC patients before treatment from a prospective study (NCT02395705). Of them, samples from Cohort 1 (E102 and E110) were sequenced by whole-exome sequencing (WES) and those from Cohort 2 (E104, E111 and E121) were sequenced by targeted captured sequencing with a panel of 560 cancer-related genes respectively. To call somatic single nucleotide variations (SNVs) by comparing the solid tumor or cfDNA with matched WBCs, the minimal variant allele frequency (VAFmin) as 0.1% and P value <0.05 were allowed. Results: Genomic DNA (gDNA) and plasma-derived cfDNA from 26 samples were successfully sequenced. In Cohort 1, 596 (596/712, 83%) and 562 (562/796, 71%) were heterogeneous SNVs in E102 and E110 respectively. There was a statistically significant linear relationship between the VAFs for tumor and cfDNA (R2 = 0.78, P <0.0001). In Cohort 2, 296 (296/323, 92%), 384 (384/423, 91%) and 331 (331/357, 93%) were heterogeneous SNVs in E104, E111 and E121respectively. cfDNA could recover an average of 60.7% (31/51; range, 35.7%-76.2%) of somatic mutations present in matched solid tumors. The correlation of VAFs between cfDNA and matched solid tumor was significantly positive (r2 =0.92, P <0.0001). Conclusions: Both sequencing approaches revealed the highly intratumoral heterogeneity in ESCC and enabled the detection of both ubiquitous and heterogeneous mutations in cfDNA. Further validation in cfDNA is required to define its potential utility for ESCC in clinical practice. Trial registrationAll patients selected in this study were from the registered clinical trial from ClinicalTrials.gov (NCT02395705). Date of registration: March 24, 2015.
Assessing the Role of Big Data and the Internet of Things on the Transition to Circular Economy: Part II : An extension of the ReSOLVE framework proposal through a literature review

This paper presents the main findings of a literature-based study of circular economy (CE) extending the technology attributes present on the Ellen MacArthur Foundation (EMF) Regenerate, Share, Optimise, Loop, Virtualise and Exchange (ReSOLVE) framework. The introduction and methods were presented in Part I (1). Part II concludes that there are 39 capabilities grouped into six elementary CE principles and five action groups, with public administration being the most interested sector, forming the CE information technology (IT) capabilities framework. It is expected the framework can be used as a diagnostic tool to allow organisations to evaluate their technological gaps and plan their IT investments to support the transition to CE.
Identification of Uncertainty Factors in the Consumer Behaviour of the New Generation of Customers at the E-commerce Level

Even though two decades have passed since the introduction of e-commerce in the B2C model, the uncertainty posed by the online environment makes many consumers reluctant to engage in online commerce. The buyer's behaviour is inherently uncertain, given that the buyer's decisions have consequences that cannot be fully predicted. In the relationship between the buyer and the seller, the perceived uncertainty is defined as the extent to which the buyer cannot accurately predict the outcome of the transaction due to factors related to the seller and the product. This paper deals with the uncertainty of the new generation of customers in the process of electronic commerce. Based on the analysis of previous research in the field of perception of and understanding of uncertainty in online transactions, the aim of this paper is to identify the sources of perceived uncertainty of Generation Y when shopping online. Research in this area was carried out using the method of the main components, based on which five factors related to uncertainty and concerns in the process of electronic commerce were extracted. The paper identifies the main factors of uncertainty perceived by customers and also verifies the correlation between these factors and the intention of the Millennials to buy. The subject matter is relevant and applicable both to the area of products but also to the area of services in the field of tourism and hospitality.
Self-Compassion and Empathy as Predictors of Happiness among Late Adolescents

Happiness is a fundamental characteristic of life, helping individuals to become healthy and productive members of society. Pakistan has been ranked as the 67th happiest country out of 156 countries in the world. Self-compassion (SC) and empathy are considered some of the finest emotions and moral values of human beings leading to a happier life. This is the first study in South Asia that examined self-compassion as a moderator between empathy and happiness. Furthermore, we also determined self-compassion and empathy as predictors of happiness among late adolescents. Data collected from 566 students, selected randomly from different educational institutions in Lahore, suggested that self-compassion (r = 0.273) and empathy (r = 0.131) had a significant positive relationship with happiness. Self-compassion and empathy both significantly predicted happiness. Male adolescents had slightly higher self-compassion and mindfulness than females. Self-compassion (F (3, 562) = 29.74, p = 0.000) was found to significantly moderate the relationship between empathy and happiness. Self-compassion can be highly beneficial to relate to oneself, specifically for adolescents who are involved in developing their identities and self-worth, and it makes their transition from adolescence to adulthood easy.
Relationship-Contingent Self-Esteem as a Moderator of Borderline Personality Features and Mate Retention

The current study examined the relationship between borderline personality features, relationship-contingent self-esteem, and mate retention behaviors. Participants (N = 204) were recruited through Amazon’s Mechanical Turk (MTurk). They completed the Personality Inventory for the DSM-5, the Rosenberg Self-Esteem Scale, the Relationship-Contingent Self-Esteem Scale, and the Mate Retention Inventory-Short Form. Participants then received feedback through the modified Future Alone Manipulation, where they were randomly assigned to one of three feedback conditions: positive, negative, or negative control. After the feedback, participants completed the Mate Retention Inventory-Short Form to assess their response to feedback. Contrary to our predictions, borderline personality features (BPF) were not correlated with relationship-contingent self-esteem (RCSE), and RCSE and threat did not moderate the relationship between BPF and mate retention behaviors (MRB). Consistent with our hypotheses, BPF predicted the used of cost-inflicting MRB. Interestingly, RCSE predicted the use of benefit-provisioning MRB. This research is the first to address the relationship between BPF and RCSE and provides insight into individuals differences in relationship behaviors.
Small Nucleolar RNA and Small Nucleolar RNA Host Gene Signatures as Biomarkers for Pancreatic Cancer

Objective: The objective of this study was to identify key molecules including small nucleolar RNAs (snoRNAs) and small nucleolar RNA host genes (SNHGs) involved in pancreatic cancer.Methods: First, we screened the differentially expressed snoRNAs (DEsnoRNAs) and trend-related snoRNAs based on the cancer genome atlas (TCGA) dataset for pancreatic cancer, and then performed methylation correlation analysis, survival analysis, and extraction of snoRNA host genes for Gene ontology (GO) functional and the Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway enrichment analysis. Next, DESNHGs and trend-related SNHGs were screened according to the TCGA dataset for pancreatic cancer, and a competing endogenous RNA (ceRNA) network was constructed for pathway and functional enrichment analysis. Results: A total of eight DEsnoRNAs and 93 trend-related snoRNAs were extracted. Then, ten host genes of the snoRNAs were identified. Functional analysis suggested that the ten host genes were significantly enriched in several GO terms including mitotic chromosome condensation and endocytosis pathway. SNORA38B was considered to associate with survival and prognosis. The SNORD17 and SNORA11 were considered to negatively correlate with methylation. In addition, two trend-related SNHGs were extracted. Additionally, a ceRNA network was constructed with 11 miRNAs, one lncRNAs, and one mRNA. SNHG24 mainly correlated with GnRH secretion and neuroactive ligand-receptor interaction in pancreatic cancer. Conclusion: The identified snoRNAs and SNHGs could serve as potential markers for the early detection of pancreatic cancer.
Computing with Spintronics: Circuits and architectures

Venkatesan, Rangharajan Ph.D., Purdue University, December 2014. Computing with Spintronics: Circuits and Architectures. Major Professor: Prof. Anand Raghunathan. With the scaling of semiconductor technology approaching its fundamental limits, several potential replacements are being actively explored to the mainstays of Silicon and CMOS. Among them, spintronics, which uses electron ‘spin’ as the state variable to represent and process information, has attracted significant interest in recent years. Spintronic devices are considered promising due to their non-volatility, near-zero leakage, and high integration density, all of which compare favorably to CMOS. However, they are not superior in all respects. Spintronic memories such as Spin-Transfer Torque Magnetic RAM (STT-MRAM) require high write energy and latency. Spintronic logic proposals such as All-Spin Logic (ASL) are limited by large current requirement for high speed operation, high short circuit power and low spin-diffusion length of spin interconnects. Therefore, spintronic devices are neither universal nor drop-in replacements. This creates the need for new designs at the circuit and architecture levels that exploit the strengths of spintronic devices and mask their weaknesses. This thesis makes the following contributions towards the design of computing platforms with spintronic devices. • It explores the use of spintronic memories in the design of a domain-specific processor for an emerging class of data-intensive applications, namely recognition, mining and synthesis (RMS). Two different spintronic memory technologies— Domain Wall Memory (DWM) and STT-MRAM—are utilized to realize the different levels in the memory hierarchy of the domain-specific processor, based
PAPR reduction in optical OFDM systems using asymmetrically clipping and signal scrambling technique

Optical orthogonal frequency division multiplexing (OOFDM) is a promising technology in the next generation of high-speed and long-haul optical transmission, due to its high spectral efficiency, high speed of data transmission and strong ability of anti-dispersion. But optical OFDM system has a very high peak-to-average power ratio (PAPR). High PAPR will bring instantaneous high optical power to the optical OFDM system. Asymmetrically clipping and signal scrambling based on fast Hartley transform for PAPR reduction is proposed in optical OFDM system. Firstly, IFFT/FFT module in each sub-block of traditional signal scrambling technique is replaced with inverse fast Hartley transform (IFHT) and fast Hartley transform (FHT) module, which yield to the real signal in OOFDM system. Then, asymmetrically clipping technique is applied to turn it into a positive and real signal. Finally, the signal with the minimum PAPR is selected for transmission in the fiber channel. The PAPR of the optical OFDM signal can be reduced effectively. And without the Hermitian symmetry, the space and computational complexity are reduced accordingly.
Expansion driven Unstable Two Phase Flows in Long Risers and Wells

Flow instabilities in long wells and risers under certain flow conditions, is well known. Expansion driven flow instability (EDI) which is relatively little known, refers to occurrence of flow instabilities in long wells and risers as a result of entrapment of gas upstream of the well or riser base. EDI can also occur in gas-lift systems at low pressure and low gas injection rate. This work was initiated to tackle flow instability problem related to deep water production operations where long wells and risers are extensively in use. The aim of this thesis is to investigate a type of flow instability known as Expansion Driven Flow Instability (EDI) in Long Wells and Risers. This involves experimental investigation as well numerical modelling of expansion driven flow instability in long wells and risers. Finally results of the experimental investigations are compared with numerical model data. An experimental flow loop was setup to verify EDI at varying pipe geometry, inlet flow pressure and gas flow rate to examine the effect of EDI in long wells and risers. The laboratory experiment was conducted using air and water at atmospheric conditions, in a flowline-riser system consisting of a 32mm diameter and 9.12m long riser. The expansion driven flow cycle was captured in video recording. Variation of inlet flow pressures was achieved by varying the height of the overflow tank. Three cases were considered, each at a different inlet pressure. Each inlet pressure of the fluid was examined against varying inclination angles of the horizontal pipe to the riser inlet. Different gas flow rates were tested at different inclination angles. It was observed that inclination angle has the greatest impact on EDI. Experimental result of one of the cases was modelled using OLGA and the results of the experimental compared against simulation results output. Discrepancies in the two sets of results were observed in some cases. These may be attributed to simplifications and assumptions made during the simulation model build. Both results of the experimental investigation and numerical simulation demonstrated that expansion driven flow instability can occur in laboratory setup and can probably occur in deep water natural-lift wells and risers as well as gas-lifted wells and risers under certain flow conditions and pipe inclinations.
Molecular Divergence in Flea Ctenocephalides Canis From West and Northwest of Iran

BackgroundFleas of the family Pulicidae are the most common ectoparasites infesting domestic livestock worldwide. The main aim of the present study was to demonstrate the degree of molecular divergence between Ctenocephalides canis fleas in the Western and Northwestern of Iran, based on nuclear and mitochondrial genes, including ITS1and ITS 2 and cytochrome c-oxidase 1 (cox1) mtDNA. MethodsA total of 918 C. canis fleas was collected. The obtained morphometric data and DNA sequencing results did not show significant differences between C. canis specimens from the different regions or hosts. However, there was a significant degree of molecular divergence among the ten populations based on nuclear markers.ResultsThe degree of molecular divergence between different isolates of C. canis based on ITS1and ITS 2 genes was 0.15% and 3.36%, respectively. But analysis of the sequencing results shows that there was no molecular divergence between the ten populations based on the Cox1 marker.ConclusionsStudy of internal transcribed spacer ITS1 and ITS2 of rDNA and the partial cox1 mtDNA gene showed that these fragments are useful tools for interspecific divergence rates, species-level differentiation and confirm the diagnosis of species C. canis.
Noscapine as Anticancer Agent & Its Role in Ovarian Cancer

Cancer is a public health problem accounting for an estimated 9.6 million deaths worldwide, according to the latest WHO report, mainly affecting low-middle income countries. Noscapine (narcotize), a non-toxic benzylisoquinoline alkaloid derived from opium poppy, is commonly used as a cough suppressant in humans and exhibited various activities against a variety of cancers with unclear mechanism of action. Unlike other alkaloids obtained from opium poppy, noscapine is not sleep-inducing, hypnotic drug, rendering it as non-addictive drug and therefore used as antimitotic & antitussive drug around the world, can be orally consumed. Ovarian Cancer is one of the common causes of gynecologic cancer affecting women around the world. The main reason for treatment failure and mortality is the drug resistance against DDP (cisplatin), which has emerged the use of Noscapine against drug-resistant ovarian cancer cell line SKOV3/DDP by activation of apoptosis. Herein, we will describe noscapine chemically; its medicinal utility and pharmacological history behind the noscapine family of compounds then follow its journey for treating ovarian cancer (Figure 1).
Perception of COVID-19 During the 2020 Pandemic in Russia

In order to study the perception of the COVID-19 pandemic and its relationship with the emotional state of the population, an online study in all regions of Russia conducted from April 27 to May 27, 2020, The study involved 1192 people, of whom 981 were women (82%) and 211 men (18%) aged 18 to 81 years (M=36.5, SD=11.0). The methodological complex consisted of a socio-demographic questionnaire, the state scale from the State-Trait Anxiety Inventory, the Russian Version of the Perceived Stress Scale (Cohen, Kamarck, Mermelstein, 1983; Ababkov, et al., 2016); as well as the Russian Version of the Brief Illness Perception Questionnaire (Broadbent, et al., 2006; Yaltonsky, et al., 2017), modified specifically for this study. Significant differences were found in experiencing stress, anxiety, and perceptions of the pandemic by gender, while anxiety and stress were found to be related to income. A significant correlation found between the attitude to coronavirus “as an exaggerated threat” with greater calm, greater understandability of the pandemic, and less control. However, if the respondent has relatives who have got sick COVID-19, then the perception of the pandemic becomes more threatening, less understandable, and more controlled. It was revealed that the assessment of the threat from a pandemic plays a mediating role between the fear of an unknown disease and the possibility of its control. The probability of cultural differences in the perception of the pandemic and its control is discussed, and the possibility of using the cultural-historical methodology and the concept of “subjective pattern of disease” to assess the public perceptions of the COVID-19 pandemic is formulated.
Integracja projektowania i kosztorysowania na platformie BIM

In the paper the idea of CAD and estimation cost systems were considered where BIM technology in multidimensional design was applied. The exchange between various CAD systems using IFC format were depicted. Two methods of cost calculations were presented – estimated and detailed. The new system ZuziaBIM showed automated process of taking off based on directly imported models from various branch applications. The example of detailed cost calculation was included.