Miracle-dz/UniFAR-FTUs huggingface dataset:
Transcriptional Control of the Inducible Nitrate Reductase Isoform in Soybean, Glycine Max

Nitrate reductase (NR) is the first enzyme of the nitrate assimilatory pathway of higher plants. It catalyses the reduction of nitrate to nitrite, which is generally regarded as the rate limiting step in nitrate assimilation. We have measured steady-state mRNA levels of the inducible nitrate reductase isoform in soybean seedlings. Ten (10) day old seedlings were irrigated with nutrient media differing in nitrate content. These nutrient media contained: 1) zero nitrate 2) 10 mM glutamine 3) lOmM glutamine and 50 mM KN03 4) 50mM KN03 • Poly A+ mRNA was isolated from primary leaves forty eight (48) hours after nutrient treatment, and slotted onto a nylon membrane. Hybridization was performed with a 1.2 kb cDNA clone for squash NR. It was found that seedlings treated with zero nitrate or lOmM glutamine possessed no measurable amounts of inducible NR transcript. Those treated with both lOmM glutamine and 50mM KN03 showed intermediate with 50 mM transcript levels, and KN03 showed high levels seedlings treated of inducible NR transcript. We also examined inducible NR transcript levels at several time points after treatment, including a point during the dark portion of the photoperiod. We observed NR specific transcript appearing two (2) hours after treatment, peak levels were seen twenty-four (24) iv and forty-eight (48) hours after treatment. Much reduced levels of inducible NR transcript were observed in mRNA samples isolated from dark harvested leaves. This may indicate some form of light specific control regulating inducible NR transcript levels, in addition to the regulation of transcript levels observed in the nutrient treatment groups. Nuclear run-on transcription assays performed with nuclei isolated from seedlings treated as above, provide evidence indicating that fluctuations seen in steady state NR transcript levels due to nitrate treatment and light are controlled at the level of transcription.
HELIQUEST : a web server to screen sequences with specific α-helical properties

Summary: HELIQUEST calculates the physicochemical properties and amino acid composition of an α-helix and screens databank to identify protein segments possessing similar features. This server is also dedicated to mutating helices manually or automatically by genetic algorithm to design analogues of defined features. Availability: http://heliquest.ipmc.cnrs.fr Contact: gautier@ipmc.cnrs.fr
In vitro growth responses of two citrus species, i.e. Pummelo (Citrus grandis L.) and Key lime (Citrus aurantifolia Cristm.) in various sucrose concentrations

Studies were performed to investigate in vitro growth responses of seeds of two citrus species, viz. Pummelo and Key lime in various sucrose concentrations in an attempt to generate cost efficient in vitro citrus plant. Mature seeds collected from ripe fruits and after surface sterilization were cultured on different sucrose concentration containing MS media and compared them with control. The results were scrutinized by different parameters namely on seed swelling, radical and first root emergence, first and second pair leaf emergence. In seed swelling experiment, 2.50 % sucrose containing media for Pummelo and sucrose free medium for Key lime showed best performance. Radical emergence and first root initiation was observed best in 2.50 % sucrose containing MS media in both citrus species. First pair of leaf emergence was better in MS0 and 2.50 % of sucrose containing media in Pummelo whereas 1.0 %, 2.0 % and 2.50 % sucrose concentration showed better result in Key lime. In case of second pair leaf proliferation there were no impact of sucrose concentration on leaf formation but fast response depend on sucrose concentration and 2.50 % sucrose containing media showed best response in both citrus. Root induction from in vitro grown shoots-cutting was responded quickest in 1.0 % sucrose containing media in both citrus. Plantlets of both citrus species generated through in vitro culture were able to acclimatize successfully and confirmed natural growth on soil when transferred them in earthen pots.
Bullish Bearish Strategies of Trading a Nonlinear Equilibrium

We study a financial market where risk-neutral traders are endowed with a signal that perfectly reveals the direction (but not the exact amount) of the liquidation value of a normally distributed risky asset. The impact of order flow on prices is nonlinear with a bullish/bearish information structure, which is broadly consistent with empirical evidence. Also, private information is revealed quicker than in a strategic oligopoly.
Pharmacologyoline 1 : 17-29 ( 2010 ) Deepika and Kannabiran 17 ANTAGONISTIC ACTIVITY OF STREPTOMYCES VITDDK 1 spp . ( GU 223091 ) ISOLATED FROM THE COASTAL REGION OF TAMIL NADU , INDIA

Our continuous searches for antagonistic actinobacteria lead to the isolation of Streptomyces VITDDK1 spp.from the soil sample collected at the Ennore saltpan region, Tamil Nadu, India. The isolate exhibited significant antibacterial activity against the gram negative pathogenic bacteria, Escherichia coli, Klebsiella pneumoniae and Pseudomonas aeruginosa and antifungal activity against pathogenic Aspergillus flavus. Also the isolate possessed fairly moderate chitinolytic activity. Morphological and chemotaxonomic studies showed that the isolate belonged to the genus Streptomyces. Based on polyphasic taxonomy and phylogeny the isolate was designated as Streptomyces VITDDK1 spp. Further the isolate showed 99% similarity with the strain Streptomyces sp. J-1.
Effects of different cytokinins on in vitro multiplication of Prunus 'Capdeboscq' rootstocks

Rootstocks for peach trees are obtained in Brazil from seeds without genetic uniformity or health guarantee. Micropropagation techniques supply genetically uniform shoots but the in vitro culture protocols must be optimized. Cytokinins are essential for breaking the apex dormancy and inducing auxiliary shoot proliferation that influence the success of in vitro multiplication. The objective of this study was to assess the effect of different cytokinins in vitro multiplication rate, and on the survival rate of apical and axyllary buds in the establishment of Prunus ‘Capdeboscq’ rootstocks. Apical and axyllary buds were inoculated in test tubes containing 10mL Lepoivre culture medium, supplemented with BAP (0.5 mg L -1 ). After two subcultures of the in vitro establishment process, 1-2 cm nodal segments were treated with kinetin, isopentenyladenine and BAP, at concentrations of 0.1; 0.5; 1.0 and 2.0 mg L -1 . At the in vitro establishment phase, stem tips presented greater survival, less contamination and no hyperhidricity. BAP gave the highest in vitro multiplication rate, with 25.9 shoots/explant at the 1.5 mg L -1 . The different cytokinins did not result in differences in shoot height. The best results for the number of shoots greater than 20 mm were obtained with BAP at 1.0 mg L -1 .
Neural Coding of Computational Factors Affecting Decision Making 16

We constantly need to make decisions that can result in rewards of different amounts with different probabilities and at different timing. To characterize the neural coding of such computational factors affecting value-based decision making, we have investigated how reward information processing is influenced by parameters such as reward magnitude, probability, delay, effort, and uncertainty using either fMRI in healthy humans or intracranial recordings in patients with epilepsy. We decomposed brain signals modulated by these computational factors, showing that prediction error (PE), salient PE, and uncertainty signals are computed in partially overlapping brain circuits and that both transient and sustained uncertainty signals coexist in the brain. When investigating the neural representation of primary and secondary rewards, we found both a common brain network, including the ventromedial prefrontal cortex and ventral striatum, and a functional organization of the orbitofrontal cortex according to reward type. Moreover, separate valuation systems were engaged for delay and effort costs when deciding between options. Finally, genetic variations in dopamine-related genes influenced the response of the reward system and may contribute to individual differences in reward-seeking behavior and in predisposition to neuropsychiatric disorders. 1 BASIC COMPUTATIONS INVOLVED IN DECISION MAKING We constantly need to make decisions that can result in rewards of different amounts, types, probabilities, and which occur at various delay durations. To characterize the neural coding of such computational factors affecting value-based decision making,
Diabetes mellitus Hypertension Tuberculosis Sarcoidosis Fabry ’ s disease SLE Chronic liver disease Sickle cell disease Wegener ’ s granulomatosis Multiple myeloma Systemic amyloidosis Chronic lead toxicity Post – bone marrow transplant

The cardio-renal syndromes (CRS) recently were defined systematically as disorders of the heart or kidney whereby dysfunction of one organ leads to dysfunction of another. Five types of CRS are defined. The first four types describe acute or chronic cardio-renal or renocardiac syndromes. Type 5 CRS refers to secondary cardio-renal syndrome or cardio-renal involvement in systemic conditions. It is a clinical and pathophysiological entity to describe the concomitant presence of renal and cardiovascular dysfunction. Type 5 CRS can be acute or chronic and it does not strictly satisfy the definition of CRS. However, it encompasses many conditions in which combined heart and kidney dysfunction is observed. Because this entity has been described only recently there is limited information about the epidemiology, clinical course, and treatment of this condition. Semin Nephrol 32:49-56 © 2012 Elsevier Inc. All rights reserved.
The Stability of the Euro-Demand Function

While the empirical literature on money demand is vast by any standards, it is relatively silent when it comes to the Euro, a major currency in the world. This hampers efforts, for example, to determine whether or not the European Central Bank can target monetary aggregates for inflation control. The difficulty has come from the lack of information about euro-wide monetary behavior, relying instead on speculative techniques for aggregating country-level data from previous periods of the European exchange rate mechanism. Now that we have six years of monthly data points, we investigate the stability of various Euro-zone monetary aggregates using the Bound Testing Procedure of Cointegration proposed by Pesaran et al. (2001) and study their policy implications.
Curie temperatures of zinc-blende half-metallic ferromagnets

Using density-functional theory in the local-density approximation and spin-fluctuation theory, the Curie temperatures of the zinc-blende half-metallic ferromagnets VAs, CrAs, MnAs and the Heusler compound NiMnSb have been estimated, the lower bounds obtained being ah initio. The orders of magnitude are the same as the Curie temperature of the half-metallic ferromagnet NiMnSb with T c = 701 K. Of the three compounds VAs, CrAs, and MnAs, the highest T c is calculated for CrAs, for which the Fermi energy is in the middle of the minority-spin electron gap; its Curie temperature might be as high as 1000 K. The Curie temperature drops sharply when the Fermi energy moves into the minority-electron conduction band as in the case of MnAs.
Optimization of the Operation of Smart Rural Grids through a Novel Energy Management System

The paper proposes an innovative Energy Management System (EMS) that optimizes the grid operation based on economic and technical criteria. The EMS inputs the demand and renewable generation forecasts, electricity prices and the status of the distributed storages through the network, and solves with an optimal quarter-hourly dispatch for controllable resources. The performance of the EMS is quantified through diverse proposed metrics. The analyses were based on a real rural grid from the European FP7 project Smart Rural Grid. The performance of the EMS has been evaluated through some scenarios varying the penetration of distributed generation. The obtained results demonstrate that the inclusion of the EMS from both a technical point of view and an economic perspective for the adopted grid is justified. At the technical level, the inclusion of the EMS permits us to significantly increase the power quality in weak and radial networks. At the economic level and from a certain threshold value in renewables’ penetration, the EMS reduces the energy costs for the grid participants, minimizing imports from the external grid and compensating the toll to be paid in the form of the losses incurred by including additional equipment in the network (i.e., distributed storage).
188 X-Similarity Comparison by Using Wordnet

Semantic web is an addition of the previous one that represents information more significantly for humans and computers. It enables the description of contents and services in machine readable form. It also enables annotating, discovering, publishing, advertising and composing services to be programmed. Semantic web was developed based on Ontology which is measured as the backbone of the semantic web. Machine-readable is transformed to ma-chine-understandable in the current web. Moreover, Ontology provides a common vocabulary, a grammar for pub-lishing data and can provide a semantic description of data which can be used to conserve the Ontology and keep them ready for implication. There are many that used in feature based in semantic similarity. This research presents a single ontology of X-Similarity feature based method. Keywords— X-Similarity, Wordnet.
Buried targets in layered media : A combined finite element / physical acoustics model and comparison to data on a half buried 2 : 1 cylinder

Vocal emotion production varies across talkers. Effects of talker variability (i.e., same talker vs different talkers across trials) on vocal emotion recognition were tested in babble noise and with cochlear implant (CI) simulations in normal-hearing listeners. Results showed significant talker variability effects in noise but not with CI simulations, suggesting that the degree of talker variability effects on vocal emotion recognition may vary with listeners’ weighting of acoustic cues for emotions (e.g., pitch and duration) and the availability of these cues in different listening conditions. Vocal emotion recognition significantly improved with higher signal-to-noise ratio and more vocoder channels. VC 2016 Acoustical Society of America [Q-JF] Date Received: August 19, 2016 Date Accepted: November 22, 2016
How do Visitor Density and Anthropogenic Change in Frontcountry Wilderness Settings Affect Recreation Benefits

Effects on recreation benefits were assessed using ques- tionnaires and image sets depicting visitor density ranges and anthropogenic setting changes at two heavily-visited wilderness sites. Visitor benefits were less affected by high visitor densities at the more accessible of the two sites. New age medicine wheels had a positive effect on visitor benefits, as did trail revegetation. Al- though wilderness visitor density guidelines are frequently ex- ceeded at both sites, wilderness designation is defended as accept- able, because frontcountry wilderness borders buffer less accessible backcountry areas from excessive impacts, and provide inexperi- enced and casual visitors with non-mechanized recreation experi- ence opportunities, and exposure to wilderness.
Transient Detections and Other Real-Time Data Processing from MASTER-VWF Wide-Field Cameras

Construction of robotic observatories has developed into an important and thriving field of astronomy. Their large field of view combined with the capability to be pointed at any direction makes robotic astronomical systems indispensable for tasks involving searches for transients like GRB, supernovae explosions, novae, and so forth, where both the time and direction of the search are impossible to predict. This paper describes prompt GRB observations made with MASTER-VWF wide-field cameras and the methods of image analysis and classification of transients used for real-time data processing. During seven months of operation six synchronous observations of gamma-ray bursts have been made using MASTER VWF facilities deployed in Kislovodsk and Irkutsk. In all cases high upper limits have been obtained.
LETTERS TO THE EDITOR Overexpression and Dysregulation of bcl-2 in Lymphocyte Subpopulations of Synovial Membrane

Overexpression and Dysregulation of bcl-2 in Lymphocyte Subpopulations of Synovial Membrane SIRÐIn agreement with Liang et al. [1], we also found a very strong bcl-2 mRNA expression in the synovial lining cells of synovial membranes (SMs) derived from patients with chronic rheumatic disorders, but we did not ®nd a corresponding protein expression. This ®nding was comparable to the expression pattern in tonsillar epithelium, where no strongly stained cells for bcl-2 protein were present, but the in situ hybridization (ISH) staining was strong in epithelial cells except for super®cial layers [2]. We conclude that the expression of bcl-2 mRNA and bcl-2 protein in the synovial lining layer re ̄ects bcl-2 expression in epithelium, while it may be dysregulated in the follicular aggregates of lymphocytes in the SM (Figs 1 and 3). By its function of preventing cells from apoptosis [3, 4], the bcl-2 protein plays an important role in B-cell dierentiation in germinal centres [5, 6]. Some investigations have shown that the protein and mRNA expression of bcl-2 do not necessarily correlate. In germinal centre cells, the bcl-2 mRNA is highly expressed, whereas the bcl-2 protein expression is strong in the follicular mantle zone [2, 7]. In rheumatoid arthritis (RA), the transformation of the SM to immunologically active tissue with in®ltration of B and T lymphocytes [8] and macrophages, which in some cases form follicular aggregates [9], is a characteristic feature besides the proliferation of synoviocytes. Recent investigations characterized these aggregates in some cases as germinal centres comparable to those in lymph nodes or spleen [10]. In an earlier study [8], we showed that bcl-2 protein is overexpressed in lymphocyte subpopulations of SM of patients with RA. So we also investigated the bcl-2 mRNA pattern in RA-SM by ISH on paran-embedded tissues. Therefore, a 26-mer oligonucleotide probe labelled with digoxigenin (DiG) was used in its sense (negative control) (Figs 2 and 4) and antisense form. Hybridizations were detected by alkaline phosphatase (AP)-conjugated British Journal of Rheumatology 1997;36:1335±1343
Calcium chloride improve ethanol production in recombinant Zymomonas mobilis

The T7-expression system has been very useful for protein expression in Escherichia coli. Here, a T7- expression transposon was constructed, which allowed simple construction of T7-expression Zymomonas mobilis. This transposon contained the T7 RNA polymerase being driven by the gap promoter from Z. mobilis. The T7-expression fadK genomes were introduced into Z. mobilis ATCC 31821 in order to increase ethanol production. The recombinant bacteria were named as Z.M. F-1, Z.M. F-2, Z.M. F-3, and Z.M. F-4. However, Z.M. F-4 had the highest ability of producing ethanol by selection. Compared with Z. mobilis ATCC 3182, there was 7% increase in ethanol production for Z.M. F-4 with corn hydrolyaztes as fermentation medium. The 16 mmolL -1 supplement of calcium chloride could significantly improve the ethanol production. This was also clearly demonstrated by a variety of kinetic parameter values over time in Z.M. F-4 under high sugar osmotic stress. Calcium chloride not only increased the fermentation ability but also improved the stability of cell membrane. Key words: Calcium chloride, fadK, fermentation, Zymomonas mobilis.
Flexors Extensors Elbow joint Biceps brachii Triceps brachii Hip joint Iliacus Gluteus maximus Knee joint Biceps femoris

Optimal performance of adaptive restraint systems in the vehicle requires an accurate assessment of occupant characteristics including physical properties and pre-collision response of the occupant. To provide a feasible framework for incorporating occupant characteristics into adaptive restraint schemes, this study evaluates the sensitivity of injury risk in frontal collisions to four occupant parameters: mass, stature, posture and bracing level. The numerical approach includes using commercial multi-body software to develop occupant models that span a range of occupant parameters representative of the real-world driver population. Coupled with a multi-body model of the vehicle interior and standard restraint system, risk of occupant injuries within specific body regions are predicted through numerical simulations in conjunction with established injury risk functions. The results show occupant posture to be the most significant parameter affecting the overall risk of injury in frontal collisions. The causal relationship as predicted using the numerical model has been compared to the traffic injury epidemiology findings, and the feasibility of an analytical methodology to provide real-time estimates of injury severity has been discussed. Preliminary estimates from the study indicate that the proposed methodology will provide a framework to optimize restraint performance and potentially reduce the risk of injuries up to 35% (based on parameter-specific optimization), using accurate information regarding the pre-collision occupant
Lactamase-Producing Enterobacteriaceae in Empiric Therapy of 2 Community-Onset Sepsis ?

Please cite this article as: Daša Stupica, Lara Lusa, Mirijam Nahtigal Klevišar, Sara Terzić, Mateja Pirš, Manica Mueller Premru, Franc Strle, Should we consider fecal colonization with extended-spectrum β-lactamase-producing enterobacteriaceae in empiric therapy of communityonset sepsis? , International Journal of Antimicrobial Agents (2017), http://dx.doi. org/doi: 10.1016/j.ijantimicag. 2017.06. 019.
ercc1 protein expression predicts survival in patients with high-grade, non-metastatic osteosarcoma treated with neoadjuvant chemotherapy Short running title: ercc1 clinical impact in high-grade osteosarcoma

This article has been accepted for publication and undergone full peer review but has not been through the copyediting, typesetting, pagination and proofreading process which may lead to differences between this version and the Version of Record. Please cite this article as an 'Accepted Article', doi: 10.1111/his.12653 This article is protected by copyright. All rights reserved. Article Type: Original Article
VIP: A Versatile Inference Processor

We present Versatile Inference Processor (VIP), a highly programmable architecture for machine learning inference. VIP consists of 128 lightweight processing engines employing a vector processing paradigm, with a simple ISA and carefully chosen microarchitecture features. It is coupled with a modern, lightly customized, 3D-stacked memory system. Through detailed execution-driven simulations backed by RTL synthesis, we show that we can achieve online, real-time vision throughput (24 fps), at low power consumption, for both fullHD depth-from-stereo using belief propagation, and VGG-16 and VGG-19 deep neural networks (batch size of 1). Our RTL synthesis of a VIP processing engine in TSMC 28 nm technology, using a commercial standard-cell library supplied by ARM, results in 18 mm2 of silicon area and 3.5 W to 4.8 W of power consumption for all 128 VIP processing engines combined.