Miracle-dz/UniFAR-FTUs huggingface dataset:
Superbug horror and its relations to antibiotics, probiotics and vitamins

Recent crisis in human health is mostly due to spread of multidrug-resistant bacteria or superbugs. Molecular analysis has indicated integrons and R-plasmids (2-15 kb) have combined with F’-conjugative plasmid (62 kb) producing large MDR-Plasmids (50-500 kb) that could donate mdr genes to all bacteria present in the intestine. We used >20,000 tons antibiotics each year to remove bacteria from our body and thus eradicated >35,000 species of gut microbiota from intestine that produce vitamins (riboflavin, pantothenate, niacin, folate, biotin, etc.). We now use probiotic capsule with ~10 bacteria (Lactobacillus, Bifidobacterium, Streptococcus, etc.) but many gut microbes are hard to grow and study in vitro. Thus, antibiotics have produced a greater crisis that human would be extinct unless mdr genes are created and diversified to withstand the new drug derivatives discovered every year! The crisis of vitamins is obvious as bacterial plasmids have been acquiring vitamin synthesizing genes and other genes related to complex biomolecules synthesis. Bacteria know that a further great war will be awaited as scientists will produce more deadly antibiotics and are acquiring multiple (20-60) gene rearrangement cassettes (IntI, Tn3, Tn5, Tn30, IS-26, etc.) in large plasmids for mdr gene creation. Moreover, intestinal cells also need lipopolysaccharides, linolinic acid, taurocholic acids and butyrate, etc., and stay in a tight symbiotic control over producing cytokines, interleukins and immuloglobins. Superbugs NDM1 Escherichia coli, MRSA Staphylococcus aureus, MDR Acinetobacter baumannii and XDR Mycobacterium tuberculosis, etc., are hard to treat due to accumulations of amp, blaNDM1, blaOXA23, tetA/C, mexAB, arr3, catB3, sul1/2, dhfr, penA, acrAB, mtrCD, aacC1, aadA2, aphA4, aacA4, mcr-1, etc., MDR genes and DEGs (acrAB, tetA/C, mcr, mtrCD, mexAB-EF) in plasmids and chromosome(s) as well as mutations in the antibiotic targets like gyrB, parC, porB, 16S rRNA, rpsL genes. WHO has warned for reduced antibiotic use and G-20 Nations are together to address the anticipated antibiotic horror, not superbug horror. Perhaps, phage therapy, gene medicines, heterogeneous phyto-antibiotics and drug nano-carriers will be future agenda to replace antibiotics.
STANISŁAW SZCZECIŃSKI CUSTOMER NEED FOR MATERIAL HANDLING IN CREATING A BUSINESS MODEL

TAMPERE UNIVERSITY OF TECHNOLOGY Master’s Degree Programme in Industrial Engineering and Management SZCZECIŃSKI, STANISŁAW: Customer need for material handling in creating a business model Master of Science Thesis, 61 pages, 1 appendix (2 pages) October 2015 Major: International Sales and Sourcing Examiner(s): Professor Miia Martinsuo
Nuclear Reactions in the Crusts of Accreting Neutron Stars

X-ray observations of transiently accreting neutron stars during quiescence provide information about the structure of neutron star crusts and the properties of dense matter. Interpretation of the observational data requires an understanding of the nuclear reactions that heat and cool the crust during accretion and define its nonequilibrium composition. We identify here in detail the typical nuclear reaction sequences down to a depth in the inner crust where the mass density is using a full nuclear reaction network for a range of initial compositions. The reaction sequences differ substantially from previous work. We find a robust reduction of crust impurity at the transition to the inner crust regardless of initial composition, though shell effects can delay the formation of a pure crust somewhat to densities beyond . This naturally explains the small inner crust impurity inferred from observations of a broad range of systems. The exception are initial compositions with A ≥ 102 nuclei, where the inner crust remains impure with an impurity parameter of Qimp ≈ 20 owing to the N = 82 shell closure. In agreement with previous work, we find that nuclear heating is relatively robust and independent of initial composition, while cooling via nuclear Urca cycles in the outer crust depends strongly on initial composition. This work forms a basis for future studies of the sensitivity of crust models to nuclear physics and provides profiles of composition for realistic crust models.
Labour Market Returns and Wage Inequality: New Evidence for Europe

We study the relationship between returns to education and the wage distribution in Europe and we find evidence for a new fact: A hump-shaped relationship between returns and the wage distribution. This hump-shaped relationship between returns to education and the wage distribution means that investments on education contributes to increase inequality between the lower bound of the wage distribution and the median (roughly) but for the richer part of the wage distribution, education tends to decrease wage inequality. There is also evidence of a non-monotonous relationship between returns to tenure and gender, on one side, and the wage distribution, on the other side.
Effects of Periodic Wake Passing Upon Aerodynamic Loss of a Turbine Cascade: Part I — Measurements of Wake-Affected Cascade Loss by Use of a Pneumatic Probe

This paper reports on an experimental investigation of aerodynamic loss of a low-speed linear turbine cascade which is subjected to periodic wakes shed from moving bars of the wake generator. In this case, parameters related to the wake, such as wake passing frequency (wake Strouhal number) or wake turbulence characteristics, are varied to see how these wake-related parameters affect the local loss distribution or mass-averaged loss coefficient of the turbine cascade. Free-stream turbulence intensity is changed by use of a turbulence grid. In Part I of this paper a focus is placed on the measurements by use of a pneumatic five-hole yawmeter, which provides time-averaged stagnation pressure distributions downstream of the moving bars as well as of the turbine cascade. Spanwise distributions of wake-affected exit flow angle are also measured. From this study it is found that the wake passing greatly affects not only the profile loss but secondary loss of the linear cascade. Noticeable change in exit flow angle is also identified.Copyright © 1999 by ASME
Synthesis of Gold Nanoparticles Dispersed in Palm Oil Using Laser Ablation Technique

Gold nanoparticles have more applications in biology, medicine, and industry. In this study, gold nanoparticles were synthesized in pure palm oil using laser ablation technique. Gold nanoparticles were fabricated in different temperature, and the effect of the temperature on the particle size was investigated. Consequently, the tail of the carbonyl band of fatty acids was capped gold nanoparticles, and spherically shaped gold nanoparticles with size range of 8.92 to 19.73 nm were formed in palm oil. The temperature caused the agglomeration of nanoparticles while the particle size increased with an increase in the temperature.
Effects of rumen-protected folic acid and rumen-protected sodium selenite supplementation on lactation performance, nutrient digestion, ruminal fermentation and blood metabolites in dairy cows.

BACKGROUND Considering the insufficient ruminal synthesis of folic acid (FA), the higher degradability of FA, and the reduction of sodium selenite (SS) by ruminal microbes into non-absorbable elemental Se, this study evaluated the effects of rumen-protected FA (RPFA) and rumen-protected SS (RPSS) on lactation performance, nutrient digestion and blood metabolites in dairy cows. RESULTS Dry matter (DM) intake and milk composition were unaltered, milk and milk fat yields were higher for both supplements, milk protein yield was higher for RPFA addition. Digestibility of DM, neutral detergent fibre and acid detergent fibre was higher for both supplements, whereas that of organic matter and crude protein was higher for RPFA addition. Ruminal pH and ammonia N were lower, and concentration of total volatile fatty acids was higher for both supplements. Activity of cellobiase and xylanase was higher for RPFA addition, whereas that of pectinase and protease was higher for both supplements. The populations of total ruminal fungi, protozoa, Ruminococcus (R.) flavefaciens and Butyrivibrio fibrisolvens were higher for both supplements. The RPFA × RPSS interaction was significant for α-amylase activity, total ruminal bacteria and R. albus populations, these 3 variables were increased by RPSS but the increase was greater when cows were also fed RPFA. CONCLUSION The results indicated that addition of RPFA or RPSS improved lactation performance, nutrient digestibility and ruminal fermentation in dairy cows by stimulating ruminal microbial growth and enzyme activity. This article is protected by copyright. All rights reserved.
Molecular form and function of the cytokinetic ring

ABSTRACT Animal cells, amoebas and yeast divide using a force-generating, actin- and myosin-based contractile ring or ‘cytokinetic ring’ (CR). Despite intensive research, questions remain about the spatial organization of CR components, the mechanism by which the CR generates force, and how other cellular processes are coordinated with the CR for successful membrane ingression and ultimate cell separation. This Review highlights new findings about the spatial relationship of the CR to the plasma membrane and the arrangement of molecules within the CR from studies using advanced microscopy techniques, as well as mechanistic information obtained from in vitro approaches. We also consider advances in understanding coordinated cellular processes that impact the architecture and function of the CR. Summary: This Review highlights new findings about the arrangement of molecules within the force-generating cytokinetic ring from studies using advanced microscopy techniques and in vitro approaches.
Zika Virus Infection Produces a Reduction on Aedes aegypti Lifespan but No Effects on Mosquito Fecundity and Oviposition Success

A Zika virus (ZIKV) pandemic started soon after the first autochthonous cases in Latin America. Although Aedes aegypti is pointed as the primary vector in Latin America, little is known about the fitness cost due to ZIKV infection. We investigated the effects of ZIKV infection on the life-history traits of Ae. aegypti females collected in three districts of Rio de Janeiro, Brazil (Barra, Deodoro, and Porto), equidistant ~25 km each other. Aedes aegypti mosquitoes were classified into infected (a single oral challenge with ZIKV) and superinfected (two ZIKV-infected blood meals spaced by 7 days each other). ZIKV infection reduced Ae. aegypti survival in two of the three populations tested, and superinfection produced a sharper increase in mortality in one of those populations. We hypothesized higher mortality with the presence of more ZIKV copies in Ae. aegypti females from Porto. The number of eggs laid per clutch was statistically similar between vector populations and infected and uninfected mosquitoes. Infection by ZIKV not affected female oviposition success. ZIKV infection impacted Ae. aegypti vectorial capacity by reducing its lifespan, although female fecundity remained unaltered. The outcome of these findings to disease transmission intensity still needs further evaluation.
Timing of cluster-zone leaf removal and its impact on canopy morphology, cluster structure and bunch rot susceptibility of grapes

Aims : Leaf removal in the cluster-zone has proved to be an efficient option to reduce grey mould infestation. The aim of the present work was to determine the optimal timing of this measure in practical viticulture. Methods and results : Manual leaf removal in the cluster-zone was carried out at six time points between pre-bloom (BBCH 57) and veraison (BBCH 81) on the white varieties Sauvignon blanc (2009), Auxerrois (2009), Pinot gris (2010) and Riesling (2010). Leaf removal conducted between bloom and berries-touching led to a decreased number of interior clusters as well as a reduced cluster compactness and disease severity of B. cinerea . Pre-bloom and late (at veraison) leaf removal turned out to be less efficient. Conclusion : Leaf removal between bloom and berries-touching proved to be very efficient to control bunch rot due to (i) the disaggregation of the cluster structure and (ii) the improved microclimatic conditions and can be recommended in integrated as well as organic viticulture. Significance and impact of the study : The outcome of the present study constitutes an important tool for improving grape health status and, in consequence, wine quality under cool climate winegrowing conditions.
A Distributed System for Supporting Spatio-temporal Analysis on Large-scale Camera Networks

Cameras are becoming ubiquitous. Technological advances and the low cost of such sensors enable deployment of large-scale camera networks in metropolises such as London and New York. Applications such as video-base surveillance and emergency response that exploit such camera networks are continuous, data intensive, and dynamic in terms of resource requirements. Common anomalies in such application spaces include authorized personnel moving into unauthorized spaces and checking the movement of suspicious individuals as they move through the spaces. High level goal in such applications include catching such anomalies in real time and reducing collateral damage. A well-known technique for meeting this high level goal is spatiotemporal analysis. This is an inferencing technique employed by domain experts (e.g., vision researchers) to answer queries such as show the track of person A in the last 30 minutes. Performing spatio-temporal analysis in real-time for a largescale camera network is challenging. It involves continuously capturing images from distributed cameras, analyzing the images to detect and track objects of interest in the field of view of the cameras, generating an event by comparing the signature of a detected object against a database of known signatures, and maintaining a state transition table indexed by time that shows the spatio-temporal evolution of people movement through the distributed spaces. In this paper, we propose a distributed system architecture to address these challenges. We make the following contributions: (a) present the design choices for real-time spatiotemporal analysis with a view to supporting scalability (in terms of number of cameras, event rate, and known targets), (b) develop heuristics for pruning the event generation phase of spatiotemporal analysis, and (c) implement and evaluate the different design choices in a distributed system to show the scalability of our distributed system architecture.
Species interactions and distinct microbial communities in high Arctic permafrost affected cryosols are associated with the CH4 and CO2 gas fluxes.

Microbial metabolism of the thawing organic carbon stores in permafrost results in a positive feedback loop of greenhouse gas emissions. CO2 and CH4 fluxes and the associated microbial communities in Arctic cryosols are important in predicting future warming potential of the Arctic. We demonstrate that topology had an impact on CH4 and CO2 flux at a high Arctic ice-wedge polygon terrain site, with higher CO2 emissions and lower CH4 uptake at troughs compared to polygon interior soils. The pmoA sequencing suggested that USCα cluster of uncultured methanotrophs is likely responsible for observed methane sink. Community profiling revealed distinct assemblages across the terrain at different depths. Deeper soils contained higher abundances of Verrucomicrobia and Gemmatimonadetes, while the polygon interior had higher Acidobacteria and lower Betaproteobacteria and Deltaproteobacteria abundances. Genome sequencing of isolates from the terrain revealed presence of carbon cycling genes including ones involved in serine and ribulose monophosphate pathways. A novel hybrid network analysis identified key members that had positive and negative impacts on other species. OTUs with numerous positive interactions corresponded to Proteobacteria, Candidatus Rokubacteria, and Actinobacteria phyla, while Verrucomicrobia and Acidobacteria members had negative impacts on other species. Results indicate that topology and microbial interactions impact community composition. This article is protected by copyright. All rights reserved.
Modeling Speed Limit Offenders in Mauritius Using Symmetric and Asymmetric Garch Models: From Financial Modeling to Traffic Modeling

Many countries have adopted important policies in view of curbing the number of injuries/fatal road accidents with the most important being speed limit enforcement. In that respect, Mauritius has recently embarked on a strategy of using cameras in view of detecting violations to speed limits. However, the empirical literature on speed limit offenders is still very poor in terms of modeling. In essence, this paper constitutes the very first study that provides sound econometric modeling for speed limit offenders. Findings suggest that vanilla GARCH can be used to model the number of speed limit offenders. Above all, leverage effects are also noted, clearly showing the importance of the type of traffic flow of speed limit offenders which underpins the non-compliance/breach to speed limits. Furthermore, results show the presence of strong weekend effects as confirmed by the dummy variable. The research is expected to provide a momentum in the use of GARCH models for traffic modeling not only for Mauritius but also for other countries in the world.
An Efficient GPU-Based Out-of-Core LU Solver of Parallel Higher-Order Method of Moments for Solving Airborne Array Problems

The parallel higher-order method of moments (HoMoM) with a GPU accelerated out-of-core LU solver is presented for analysis of radiation characteristics of a 1000-element antenna array over a full-size airplane. A parallel framework involving MPI and CUDA is adopted to ensure that the procedures run on a hybrid CPU/GPU cluster. An efficient two-level out-of-core scheme is designed to break the bottleneck of both GPU memory and physical memory when solving electrically large and complex problems. To hide communication time between CPU and GPU, asynchronous communications are chosen to enable overlapping between communication and computation. For large problems that cannot fit in GPU memory or physical memory, the two-level out-of-core LU solver is able to achieve a speedup of about 1.6x over the traditional out-of-core LU solver based on a highly optimized math library.
VALIDATION OF THE FUNCTIONAL SOCIAL SUPPORT QUESTIONNAIRE IN SEROPOSITIVE PERSONS TO THE HIV FROM THE NORTHWEST OF MEXICO

The main objective of this study was to validate the functional social support questionnaire (Duke-UNC-11) in a sample of 67 persons living with HIV from the northwest region of Mexico. Data analysis was carried out by the following procedures in a consecutive order: the T-test for means comparison to assess the comprehensibility of the questions; an exploratory factorial analysis with varimax rotation, to determine construct validity; the Cronbach’s α coefficient to estimate reliability. The T-test gave statistical significance values of p = . 000 in the total of the questions; a one-factor structure was found with the exploratory factorial analysis with varimax rotation, with eigen value of 6.486, explaining 58.6% of the total variance; finally, an overall Cronbach’s α coefficient of . 92 was obtained with the test of reliability. The results of the factorial structure of this study are compared with those reported in other studies realized in Hispanic countries.
Thermal Analysis of NR Composite with MWCNTs Aligned in a Magnetic Field

We got the aligned carbon tube in the rubber matrix throughmagnetic field. TEM shows that Fe 3 O 4 is symmetrically coated on the outer surface of MWCNTs. Diffraction peaks corresponding to Fe 3 O 4 cubic crystal also appeared in the X-ray diffraction spectra. Thermal conductivity of composites increases by filling the appropriate content of carbon tube. If the magnetic field is larger and the direction time is longer, a greater thermal conductivity of composites can be obtained.
The relation of insulin like growth factor gene (igf-1) with some physiological characteristics of common CARP (Cyprinus carpio)

The present study was conducted to identify genotypes of insulinlike growth factor (IGF-I) and its relation with some of the physiological characteristics (glucose, AST & ALT) of common carp Cyprinus carpio in Al-Radhwaniyah Fish reservoir (Baghdad). It has been identified genotypes of insulin like growth factor by using restriction fragment length polymorphism (RFLP) in specified mutation in the site 3759T > G. Results of physiological characteristics showed that the blood glucose rate was affected significantly (p<0.05) by different genotypes as which glucose concentration in TT genotype was 87.87 mg/100, whereas about 67.21mg/100 in TG genotype. Regarding values of transaminase enzymes (AST & ALT) they did not affect significantly by any of genotypes. ALT Value in TT genotypes was 52.66 IU with 46.33 IU in TG genotypes, as for AST, the results were 87.66, 88.33 IU in TG, TT genotypes respectively. The present study conclude that the possibility of credibility upon polymorphism in insulin like growth factor as assign for physiological performance prediction of fish body and select them to be parents for coming generation.
A Survey of the polarized emission from the Galactic plane at 1420 MHz with arcminute angular resolution

Context. Observations of polarized emission are a significant source of information on the magnetic field that pervades the interstellar medium of the Galaxy. Despite the acknowledged importance of magnetic fields in interstellar processes, our knowledge of field configurations on all scales is seriously limited. Aims. This paper describes an extensive survey of polarized Galactic emission at 1.4 GHz that provides data with arcminute resolution and complete coverage of all structures from the broadest angular scales to the resolution limit, giving information on the magneto-ionic medium over a wide range of interstellar environments. Methods. Data from the DRAO Synthesis Telescope, the Effelsberg 100-m Telescope, and the DRAO 26-m Telescope have been combined. Angular resolution is ~1' and the survey extends from l = 66° to l = 175° over a range -3° < b < 5° along the northern Galactic plane, with a high-latitude extension from l = 101° to l = 116° up to b = 17°. 5. This is the first extensive polarization survey to present aperture-synthesis data combined with data from single antennas, and the techniques developed to achieve this combination are described. Results. The appearance of the extended polarized emission at 1.4 GHz is dominated by Faraday rotation along the propagation path, and the diffuse polarized sky bears little resemblance to the total-intensity sky. There is extensive depolarization, arising from vector averaging on long lines of sight, from H II regions, and from diffuse ionized gas seen in Hα images. Preliminary interpretation is presented of selected polarization features on scales from parsecs (the planetary nebula Sh 2-216) to hundreds of parsecs (a superbubble GSH 166-01-17), to kiloparsecs (polarized emission in the direction of Cygnus X).