Miracle-dz/UniFAR-FTUs huggingface dataset:
Randomized study between thymoglobulin and posttransplant cyclophosphamide in patients with chronic myeloid neoplasms undergoing unrelated allogeneic stem cell transplantation

Elena V. Morozova, Ivan S. Moiseev, Yulia Yu. Vlasova, Nikolay Yu. Tcvetkov, Yulia V. Rudnitskaya, Maria V. Barabanschikova, Anna G. Smirnova, Elena I. Darskaya, Sergey N. Bondarenko, Boris V. Afanasyev Raisa Gorbacheva Memorial Research Institute of Pediatric Oncology, Hematology and Transplantation, Pavlov University, St. Petersburg, Russia Randomized study between thymoglobulin and posttransplant cyclophosphamide in patients with chronic myeloid neoplasms undergoing unrelated allogeneic stem cell transplantation Cellular Th erapy and Transplantation (CTT). Vol. 9, No. 1, 2020 doi: 10.18620/ctt-1866-8836-2020-9-1-53-59 Submitted: 11 November 2019, accepted: 24 January 2020
Current Trends in Dissimilar Diffusion Bonding of Titanium Alloys to Stainless Steels, Aluminium and Magnesium

This article provides a comprehensive review of the advancements made in the diffusion bonding of titanium and its alloys to other advanced materials such as aluminium, stainless steel, and magnesium. This combination of advanced alloys has received considerable attention in different industries, including aerospace, petrochemical, and nuclear applications due to high specific strength, lightweight, corrosion resistance, and moderate to high mechanical properties. The mechanisms of bond formation are discussed based on the type of microstructures formed and the mechanical properties achieved. The scientific literature identifies various methods/processes for controlling the volume of intermetallic compounds formed within the joint regions, as well as ways of maximising the strength of the weld/joints. This paper discusses the relationship between weld/bond properties and bonding parameters such as time, temperature, surface roughness, pressures, interlayer composition, and thickness. The scientific literature also shows that the bonding mechanisms and microstructural evolution of the bond zone can be significantly affected by suitable optimization of the bonding parameters. Additionally, this is a method of maximising bond strength.
Mean-field homogenization of thermoelastic material properties of a long fiber-reinforced thermoset and experimental investigation

Fiber-reinforced polymers contribute significantly to weight-reducing components for various industrial applications. A discontinuous glass fiber-reinforced thermoset resin is considered which is produced by the sheet molding compound (SMC) process. Related to the production process, the samples considered in this work exhibit an anisotropic fiber orientation distribution which highly affects the thermomechanical properties. The thermoviscoelastic material behavior of three selected samples is characterized by means of dynamic mechanical analysis. These tests show the temperature-dependent elastic modulus and the glass transition of the composite. Measurements of the thermal expansion of the SMC composite provide data on the coefficient of thermal expansion (CTE). These experimental investigations provide data for the thermoelastic material modeling. Aiming at the prediction of the effective thermal and mechanical properties, a Hashin–Shtrikman-based homogenization method is presented. Based on an eigenstrain formulation, the effective Young’s modulus and CTE are computed in two steps. Moreover, the mean-field method is given in dependence of a variable reference stiffness allowing to tailor the approach to the material system. The influence of this variable reference stiffness on the effective quantities as well as the predicted behavior is analyzed with respect to the experiments. The presented numerical results are in good agreement with the experimental data.
Demography and ecological impacts of the invading mollusc Dreissena polymorpha

The bivalve mollusc Dreissena polymorpha colonized Lake St. Clair in 1986 as a result of ballast water discharge. The present study shows that since initiating reproduction in 1988, its population density at all of the sites originally colonized has increased more than a 1000-fold. The species has, as well, expanded its range in Lake St. Clair dramatically. The density and range increase is not yet complete, as populations at most sites remain dominated by juveniles. Densities in excess of 5000 individuals/m2 seem likely to be achieved at most sites in Lake St. Clair within 5 years. It appears likely that D. polymorpha will have a significant impact on composition of the benthos. Shells of individual unionids carry in excess of 10 000 D. polymorpha, and lipid reserves of such unionids are only half those of unaffected individuals. Aside from direct interactions with benthic organisms, the filtering activity of D. polymorpha populations may be sufficient to result in a significant impact on the turbidity o.
Microstructure and mechanical properties of Ni-Al intermetallic thin coatings produced by magnetron sputtering

In the present study the thin NiAl intermetallic foils formed on different types of substrates by magnetron sputtering technique were investigated. To provide the deposition of intermetallic NiAl compound in one step without additional heat treatment the composite targets assembled from parts of Al and Al plates were used. The structure of formed thin NiAl coatings was studied using scanning electron microscopy and X-ray diffraction analysis. Mechanical properties were assessed by nanohardness indentation and wear testing of deposited coatings. During sputtering the distance from the target to the substrates varied from 60 to 100 mm to estimate the effect of this parameter on structure and properties of the coatings. The results revealed that thin coatings sputtered at the closer distance from the target to the substrates had the higher hardness about 11 GPa and exhibited the high level of wear properties.
How long can glacier foreland species live

Summary Age determinations provide information on longevity of the species and on their population structure. This knowledge is of particular interest for species involved in succession. On a glacier foreland of the Central Alps age determinations of six target species ( Saxifraga oppositifolia , Oxyria digyna , Artemisia mutellina , Anthyllis vulneraria ssp. alpestris , Trifolium pratense ssp. nivale and Helianthemum grandiflorum ) were carried out by means of herbchronology. The species were selected on three differently aged moraines in order to compare pioneer, early and late successional species. Pioneer species were expected to have young, invasive populations. This was suggested also for populations of late successional species growing towards the glacier front where they substitute the pioneer species. These hypotheses were only confirmed for the pioneer Saxifraga oppositifolia . The longest life span was found for Helianthemum grandiflorum on the oldest moraine. Plant size of all investigated individuals correlated with age. Significant differences where observed between the age of vegetative and generative individuals.
Enzymatic Hydrolysis of Inulin — An Alternative Way to Fructose Production†

In the seventies large amounts of fructose have been produced from starch by isomerization of glucose. An alternative source of fructose is inulin, present as energy reserve in plants, e. g. from the composite family such as chicory and Jerusalem artichoke. To produce fructose from inulin a hydrolysis step is necessary. This can be performed by acids, but enzyme hydrolysis is preferable because of lower byproduct formation. An enzyme specially suited for industrial application is described. Full hydrolysis of inulin more than 98% (fructose and glucose) can be achieved at 60–65°C using economical dosages of enzyme. The reasons for the special efficiency of the enzyme are touched upon.
SINE-like Sequence Insertion on Zinc Finger-Y Gene and Sexual Dimorphism in Wild Boars

Abstract Han, S-H. , Lee, S-S. and Cho, I-C. 2007. SINE-like sequence insertion on zinc finger-Y gene and sexual dimorphism in wild boars. J. Appl. Anim. Res., 32: 165–168. The sex chromosome-encoding zinc finger protein genes (ZFX and ZFY) were analyzed and tested for molecular sexing using the amplification patterns of intron 7 flanking region of ZFX-ZFY in the Korean wild boar (Sus scrofa coreanus). The amplified products from males showed two distinct bands: one was common to all DNA samples of wild boars, indicating that this band was amplified from ZFX on the X chromosome, while another was specific to just males, indicating that it might be from ZFY on the Y chromosome. A transposable element, short interspersed nuclear element (SINE)-like sequence was found on the intron 7 of ZFY but not on that of ZFX and was very similar to commonly found SINE1A_SS. We suggest that this PCR strategy for determining the sex by comparing the amplification patterns of the sexual dimorphic ZFX ZFY genes on the X and Y chromosomes is a convenient and precise method for discriminating the sex in wild boars.
Effect of Spin Transfer Via Eddy Current on Propagating Domain Wall in Ferromagnetic Microwire

We discuss the interaction of the magnetization in the domain-wall (DW) area with the eddy current that is induced by the DW propagation in a bi-stable microwire of a ferromagnetic metal. The ordering structure of the microwire consists of an axially magnetized inner core and an outer shell of radially or circumferentially magnetized domains. The electrical current in the ferromagnetic medium is spin-polarized; thus, it exerts the spin-transfer torque on the magnetization inside DWs. The effect is inherent in a soluble (Ishimori-like) model of the nonlinear magnetization dynamics that is adapted to describing the inner core of the microwire. Previously established static DWs in microwires are known as transverse, vortex, planar, and conical DWs, of whom planar DWs are specific due to lack of rotational symmetry. We analyze dynamical single-DW solutions, thus noticing our model to be capable of describing an observed unidirectional effect in the field-driven propagation of planar DWs. Thus, we claim a significant eddy-current effect on moving DW to realize in DWs of that kind.
Rapid response of the East Asian trough to Tibetan Plateau snow cover

Tibetan Plateau snow cover (TPSC) has subseasonal variations and rapidly influences the atmosphere. In this study, we present the rapid response of the East Asian trough (EAT) within a week to subseasonal variations in TPSC during the boreal winter. Using snow cover analysis obtained from the daily interactive multisensor snow and ice mapping system and the ERA‐Interim reanalysis, a considerable relationship between TPSC and 500‐hPa geopotential height anomalies over the downstream EAT region is found. Significant negative (positive) 500‐hPa geopotential height anomalies originating from the Tibetan Plateau and moving into the EAT region appear within a week following anomalous positive (negative) TPSC events, which lead to changes in EAT strength. Thus, a significantly enhanced (reduced) intensity of the EAT occurs approximately 5–6 days after increased (decreased) TPSC. Numerical experiments confirm the causality of this relationship. Further analysis of the quasi‐geostrophic geopotential height tendency equations in numerical experiments indicates that such EAT variations result from anomalous thermal advection from the Tibetan Plateau forced by TPSC.
Radiogenomics of lung cancer

Machine learning (ML) and artificial intelligence (AI) are aiding in improving sensitivity and specificity of diagnostic imaging. The rapid adoption of these advanced ML algorithms is transforming imaging analysis; taking us from noninvasive detection of pathology to noninvasive precise diagnosis of the pathology by identifying whether detected abnormality is a secondary to infection, inflammation and/or neoplasm. This is led to the emergence of “Radiobiogenomics”; referring to the concept of identifying biologic (genomic, proteomic) alterations in the detected lesion. Radiobiogenomic involves image segmentation, feature extraction, and ML model to predict underlying tumor genotype and clinical outcomes. Lung cancer is the most common cause of cancer related death worldwide. There are several histologic subtypes of lung cancer, e.g., small cell lung cancer (SCLC), non-small cell lung cancer (NSCLC) (adenocarcinoma, squamous cell carcinoma). These variable histologic subtypes not only appear different at microscopic level, but these also differ at genetic and transcription level. This intrinsic heterogeneity reveals itself as different morphologic appearances on diagnostic imaging, such as CT, PET/CT and MRI. Traditional evaluation of imaging findings of lung cancer is limited to morphologic characteristics, such as lesion size, margins, density. Radiomics takes image analysis a step further by looking at imaging phenotype with higher order statistics in efforts to quantify intralesional heterogeneity. This heterogeneity, in turn, can be potentially used to extract intralesional genomic and proteomic data. This review aims to highlight novel concepts in ML and AI and their potential applications in identifying radiobiogenomics of lung cancer.
Relationship of Multispectral Radiometry Data to Qualitative Data in Turfgrass Research

Multispectral radiometry provides a method for assessing plant light reflectance in the visible and near-infrared ranges. Reflectance of narrow wavelength ranges as well as ratios of different ranges have highly correlated with absorbency of photosynthetically active radiation, leaf area index (LAI), and plant response to stresses. The objectives of this research were to determine if data obtained by multispectral radiometry might accurately correlate with qualitative data (used as rapid estimates of color, density, and uniformity) typically used in turfgrass research. Furthermore, it was our objective to determine whether multispectral radiometry could discriminate between stressed and nonstressed turfgrass plots. This research was conducted in two consecutive trials during 1997 on seven seashore paspalum (Paspalum vaginatum Swartz) ecotypes and three hybrid bermudagrass (Cynodon dactylon L. × C. transvaalensis Burtt-Davy) cultivars established on a native Appling (clayey, kaolinitic, thermic Typic Kanhapludult) soil at the University of Georgia Experiment Station in Griffin, GA. Reflectance at 661 and 813 nm, as well as the ratios normalized difference vegetation index (NDVI, computed as R 935 - R 661 /R 935 + R 661 ), infrared/red (IR/R) (LAI, computed as R 935 / R 661 ), Stressl (R 706 /R 760 ), and Stress2 (R 706 /R 813 ) were highly correlated with visual turf quality, shoot density, and shoot tissue injury (STI) ratings, but not with shoot clipping growth. Regression analysis also indicated very strong associations with each of these qualitative variables, but not with shoot growth data. Additionally, spectral measurements at all wavelengths except 559 and 706 nm were able to consistently distinguish between wear-treated and untreated plots. This methodology may have applications in both turfgrass research and management to provide quantitative measures with physiological significance to traditional visual qualitative estimates of shoot aspects.
Electrically Switchable Semiloop Antenna with Polarization and Pattern Diversity

This paper proposes a coplanar waveguide (CPW)-fed semiloop antenna with switchable linear polarization and radiation pattern. This design uses a novel asymmetric coplanar strip line (ACPS) circular ring to produce even or odd modes of the CPW, which can generate vertical or horizontal polarization in the semiloop antenna. The modes of the ACPS circular ring can be switched by controlling the on/off state of the PIN diode, and only a two-bit control signal is required to select the operating mode. The proposed polarization switchable antenna uses only one metal layer of the printed circuit board. The center frequency of the dual-polarization antenna was determined to be 2.45 GHz, and the −10 dB impedance bandwidths were determined to be 12.86% and 4.92% for vertical and horizontal polarization, respectively. The antenna parameters, such as the return loss, gain, and radiation patterns, are also presented for validating the proposed design.
Decentralized Hierarchical Planning of PEVs Based on Mean-Field Reverse Stackelberg Game

In the reverse Stackelberg mechanism, by considering a decision function for the leader rather than a decision value in the conventional Stackelberg game, the leader can explore a wider decision space. This flexibility can result in realizing the globally optimal solution of the leader’s objective function, while controlling the reaction function of the followers, simultaneously. We consider an aggregator who purchases energy from the wholesale energy market. The aggregator acts as the leader for a group of plugged in electric vehicles (PEVs) and determines the price of energy versus consumption at each hour a day as its decision function. In the followers level, since the optimal charging strategies of the PEVs are coupled through the electricity price, the PEVs in a group are considered to cooperate in finding their Nash–Pareto-optimal charging strategy, by minimizing a social cost function. For a large number of PEVs, the cooperative cost minimization of PEVs can be modeled as a cooperative mean-field (MF) game. We propose a decentralized MF optimal control algorithm and prove that the algorithm converges to leader–follower MF $\varepsilon _{N}$ -Nash equilibrium point of the game. Furthermore, a decentralized reverse Stackelberg algorithm is implemented to achieve the optimal linear price function of the leader. Simulation results and comparison with benchmark methods are performed to demonstrate the advantages of the proposed method. Note to Practitioners—The effect of a large population of PEVs on the power grid such as overload and voltage drop is inevitable. Motivated by this, there are many research articles which propose different centralized and decentralized charging coordination solutions to address this problem. The core idea in the most of literature is: “How to IMPLEMENT a demand response (DR) program appropriately for charging coordination problem to avoid high peak load? ” However, none of them propose a practical algorithm on “How to DESIGN a DR optimally by having limited information from the clients? ” We propose a bilevel optimization algorithm to both design a DR program (i.e., price function) and also implement DR program to flatten the demand curve, accordingly. Another advantage of the proposed method is that the information structure of the problem is close to reality. There is no information exchange among the clients and also the utility company does not need to know the private information of the clients. The Utility Company only knows the charging profile of the PEVs in each day and broadcasts the price signal to the clients for the next day. The method is illustrated in an IEEE 5-bus system that supports our claims.
Attention-LSTM-Attention Model for Speech Emotion Recognition and Analysis of IEMOCAP Database

We propose a speech-emotion recognition (SER) model with an “attention-long Long Short-Term Memory (LSTM)-attention” component to combine IS09, a commonly used feature for SER, and mel spectrogram, and we analyze the reliability problem of the interactive emotional dyadic motion capture (IEMOCAP) database. The attention mechanism of the model focuses on emotion-related elements of the IS09 and mel spectrogram feature and the emotion-related duration from the time of the feature. Thus, the model extracts emotion information from a given speech signal. The proposed model for the baseline study achieved a weighted accuracy (WA) of 68% for the improvised dataset of IEMOCAP. However, the WA of the proposed model of the main study and modified models could not achieve more than 68% in the improvised dataset. This is because of the reliability limit of the IEMOCAP dataset. A more reliable dataset is required for a more accurate evaluation of the model’s performance. Therefore, in this study, we reconstructed a more reliable dataset based on the labeling results provided by IEMOCAP. The experimental results of the model for the more reliable dataset confirmed a WA of 73%.
Changes in the lipid and fatty acid composition of hemolymph and ovaries during the reproductive cycle of Labidura riparia

Lipid metabolism was investigated during the reproductive cycle of Labidura riparia (Pallas). The lipid classes and their constitutive fatty acids present in hemolymph and ovaries were measured using thin‐layer chromatography and gas‐liquid chromatography. In the hemolymph, total lipids increase steadily from the previtellogenic period to vitellogenic arrest. These lipids are predominantly diacylglycerols and phospholipids. In the ovaries, total lipids increase during vitellogenesis then decrease during the vitellogenesis arrest period. The major lipids are triacylglycerols, followed by phospholipids. In both hemolymph and ovaries, all lipid classes contained variable proportions of seven main fatty acids: the saturated fatty acids myristic acid (14:0), palmetic acid (16:0), and stearic acid (18:0); the monounsaturated fatty acids palmitoleic acid (16:1) and oleic acid (18:1); and the polyunsaturated fatty acids linoleic acid (18:2) and linolenic acid (18:3). Unsaturated fatty acids predominate throughout the reproductive cycle. The percentage compositions of total and triacylglycerol fatty acids do not change markedly during the reproductive cycle in hemolymph nor in ovaries, with 18:2, 18:1 and 16:0 fatty acids being the major components. However, for diacylglycerols and phospholipids, the proportions of fatty acids vary systematically. For phospholipids during the vitellogenesis period, 18:2 increases considerably whereas other fatty acids decrease; for diacylglycerols, these fatty acids vary in the reverse way.
The fire salamander, Salamandra salamandra L., in central Europe: subspecies distribution and intergradation

Allozyme electrophoresis of 14 loci provided information on the distribution of the two central European subspecies of the fire salamander, Salamandra salamandra salamandra (dotted taxon) and S.s. terrestris (striped taxon), along an east-west-transect in Germany. 2183 larvae from 48 populations situated in 14 mountain ranges were studies. A broad (about 140 km wide) zone of intergradition between the two forms is described, ranging from the Hunsruck Mountains in the west to the Spessart in the east. Within this hybrid zone the populations are panmictic. Focussing on the Rhenish Slate Mountains, the western border of the hybrid zone is described in detail. A comparison between allozyme data and morphognostical data (drawn from literature) on the dorsal pattern indicates a discordance between the two data sets. Consequently, the dorsal pattern is ruled out as an indicator for the detection of hybrid populations.