Miracle-dz/UniFAR-FTUs huggingface dataset:
Core@double‐shell structured multifunctional phase change microcapsules based on modified graphene oxide Pickering emulsion

New multifunctional phase change microcapsules with paraffin (Pn) as core and GO and lead tungstate (PbWO4) as double‐shell were designed by modified GO Pickering emulsion, and the effect of GO content on Pn@GO@PbWO4 microcapsules was studied. The morphology, chemical composition, and structure of Pn@GO@PbWO4 microcapsules were characterized, and their performance was studied in depth. The Pn@GO@PbWO4 microcapsules had a dense shell and a regular spherical structure. Compared with microcapsules without GO addition, the resultant Pn@GO@PbWO4 microcapsules could demonstrate high phase change reliability and thermal stability. Most of all, the anti‐seepage performance had been greatly improved by 67.27%. The results of contact angle (CA) measurement and gamma‐ray shielding test showed that the GO and PbWO4 double‐shell multifunctional microcapsules with superhydrophobic property and good gamma‐ray shielding property and high anti‐seepage performance had great attraction in expanding the application field of phase change materials.
Dissection of the genetic architecture for soybean seed weight across multiple environments

Abstract. Seed weight (SW), measured as mass per seed, significantly affects soybean (Glycine max (L.) Merr. ) yield and the quality of soybean-derived food. The objective of the present study was to identify quantitative trait loci (QTLs) and epistatic QTLs associated with SW in soybean across 129 recombinant inbred lines (RILs) derived from a cross between Dongnong 46 (100-seed weight, 20.26 g) and ‘L-100 (4.84 g). Phenotypic data were collected from this population after it was grown in nine environments. A molecular genetic map including 213 simple sequence repeat (SSR) markers was constructed, which distributed in 18 of 20 chromosomes (linkage groups). This map encompassed ∼3623.39 cM, with an average distance of 17.01 cM between markers. Nine QTLs associated with SW were identified. These QTLs explained 1.07–18.43% of the observed phenotypic variation in the nine different environments, and the phenotypic variation explained by most QTLs was 5–10%. Among these nine QTLs, qSW-3 (Satt192) and qSW-5 (Satt568) explained 2.33–9.96% and 7.26–15.11% of the observed phenotypic variation across eight tested environments, respectively. QTLs qSW-8 (Satt514) and qSW-9 (Satt163) were both identified in six environments and explained 8.99–16.40% and 3.68–18.43% of the observed phenotypic variation, respectively. Nine QTLs had additive and/or additive × environment interaction effects, and the environment-independent QTLs often had higher additive effects. Moreover, nine epistatic pairwise QTLs were identified in different environments. Understanding the existence of additive and epistatic effects of SW QTLs could guide the choice of which reasonable SW QTL to manipulate and could predict the outcomes of assembling a large number of SW QTLs with marker-assisted selection of soybean varieties with desirable SW.
Wild Strawberry Fragaria vesca L.: Kinetics of Fruit Drying and Quality Characteristics of the Dried Fruits

The aim of this study was to determine the effect of the temperature of convection and freeze–drying of wild strawberry Fragaria vesca L. fruits on the drying kinetics and on selected quality features of the dried fruits. The process of convection drying was carried out at the temperatures of 25 °C, 40 °C, and 60 °C, whereas freeze–drying was carried out at the temperatures of 20 °C, 40 °C, and 60 °C of the heating shelves and at the pressure of 63 Pa in the lyophilizer chamber. The drying kinetics were best described by the Midilli model for both drying methods. An increase of the drying temperature to 60 °C, for both convection drying and freeze–drying, resulted in a decrease of the total content of phenolic compounds and of the antioxidant activity of the dried fruits. An increase in the temperature of convection drying reduced the lightness of the dried fruits. However, during freeze–drying, these features changed little despite the increase in the drying temperature. The dried fruits with the highest brightness were obtained at a freeze–drying temperature of 60 °C. The method of freeze–drying is proposed as the best because of the resulting color, L-ascorbic acid retention, and antioxidant properties of the dried fruits.
Variation of Endogenous Hormones during Flower and Leaf Buds Development in ‘Tianhong 2’ Apple

Hormones have an important role in apple flower bud differentiation; therefore, it is necessary to systematically explore the dynamic changes of endogenous hormones during flower and leaf bud development to elucidate the potential hormone regulation mechanism. In this study, we first observed the buds of ‘Tianhong 2’ apple during their differentiation stage using an anatomical method and divided them into physiologically differentiated stages of spur terminal buds, flower buds, and leaf buds. Then, we determined the contents of zeatin riboside (ZR), abscisic acid (ABA), auxin (IAA), and gibberellin (GA3) in these various types of buds using an enzyme-linked immunosorbent assay. The results showed that the content of ZR and the ratio of ZR to IAA in spur terminal buds decreased significantly during physiological differentiation. The contents of ZR, IAA, and GA3 in leaf buds culminated at the initial differentiation stage. The content of ZR in flower buds was significantly higher than that in leaf buds after formation of the inflorescence primordium and sepal primordium. Before the appearance of stamen primordium, the content of GA3 in flower buds was remarkably lower than that in leaf buds. The ratios of ABA/IAA and ZR/IAA in flower buds were significantly higher than those in leaf buds before the appearance of flower organ primordium. Moreover, ABA content, ABA/ZR, and ABA/GA3 in flower buds were higher than those in leaf buds throughout the whole flower bud morphological differentiation process. Therefore, the reduced ZR content was beneficial to floral induction. The low content of GA3, and high ratios of ABA/IAA and ZR/IAA were conducive to early morphological differentiation. In addition, high ratios of ABA/GA3 and ABA/ZR were beneficial to the morphological differentiation of flower buds. Moreover, the high ABA content was beneficial to floral induction and morphological differentiation of flower buds. Our results shed light on the mechanisms of hormonal regulation of apple flower bud differentiation and could potentially strengthen the theoretical basis for artificial regulation of apple flower bud development using exogenous plant hormones.
An interference elimination method for CW-THz reflection imaging

We proposed a novel interference elimination method for CW-THz reflection imaging. Based on the study of interference mechanism in the imaging window, inverse processing was proposed to realize the interference elimination. Theoretical calculation showed that the interference phenomenon was closed related to the characteristics of imaging window. The refractive index and thickness of the window were the two main factors for the interference. Moreover, polarization was also taken into consideration for the CW-THz reflection imaging because the reflectivities of the s and p polarized waves were different from each other. This method was applied in different imaging systems for the demonstration of its feasibility. The high resistivity float-zone silicon (HRFZ-Si) plate was employed as the imaging window in the normal incidence system with a terahertz quantum cascade laser (THz-QCL) operating at 4.3THz. The oblique system employed quartz plate as the imaging window with an optical pumped THz laser operating at 2.52THz. Pork and liquid samples of water and edible oils were chosen as the imaging samples to demonstrate the interference elimination method.
F-18 fluorodeoxyglucose uptake in lymph nodes and sonographic features on endobronchial ultrasonography predict lymph node metastasis in lung cancer patients

Background Sonographic findings of lymph nodes on endobronchial ultrasonography (EBUS) images have been reported to be useful to predict lymph node metastasis (LNM) in lung cancer patients. F-18 fluorodeoxyglucose (FDG) uptake in lymph nodes was also found to be useful. In this study, we aimed to clarify whether a combination of sonographic features and maximum standardized uptake values of lymph nodes (LN-SUVmax) is useful for predicting LNM in lung cancer patients. Methods From January 2014 to December 2019, a total of 147 lymph nodes from 104 patients with lung cancer, who underwent preoperative EBUS and FDG-positron emission tomography (PET)/computed tomography (CT) followed by surgery were retrospectively assesses. The characteristics of the patients, LN-SUVmax, and sonographic findings of lymph nodes were reviewed. Predictive factors associated with LNM were identified using the logistic regression model. Results The average size of the lymph nodes was 8.55 (range, 3–22) mm and the average LN-SUVmax was 5.36 (range, 1.79–31.19). The prevalence of nodal metastasis was 26/147 (17.4%), including 22 in mediastinal lymph nodes and 4 in hilar lymph nodes. Multivariate analysis demonstrated four independent predictive factors for LNM; size, round or oval shape, absence of a central hilar structure, and LN-SUVmax. The optimal cutoff value for lymph node size and LN-SUVmax were 10 mm and 6.00, respectively. By combinating of the two modalities, we obtained the results with sensitivity of 76.9%, specificity of 95.1% and accuracy of 93.2%. Conclusions A combination of sonographic findings and LN-SUVmax showed a higher diagnostic rate of LNM than either modality alone in lung cancer patients.
A Survey of Free Amino Acids in Copepod Populations

• • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • •• • • • ••• • ••• • •• • •• • • •. • • • • i LIST OF TABIES •• • •••• • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • • •• • • • • • iii LIST OF FIGURES •••••••••••••••••••••••••••••••••••••••••••••••••••• iv I. II. II
Soluble VE‐cadherin contributes to loss of VE‐cadherin‐mediated adhesion and endothelial barrier function

Endothelial barrier breakdown in systemic inflammation and sepsis is a hallmark preceding organ failure and death in patients. Vascular endothelial (VE)‐cadherin‐mediated adhesion represents a crucial determinant of endothelial barrier integrity. Previously we demonstrated that under inflammatory conditions the disintegrin and metalloproteinase 10 (ADAM10) caused shedding of VE‐cadherin which resulted in the formation of soluble VE‐cadherin (sVE‐cadherin) in close temporal correlation of inflammation‐induced endothelial barrier disruption. Here we further characterized ADAM10‐induced VE‐cadherin shedding and tested whether recombinant sVE‐cadherin inferes VE‐cadherin mediated adhesion.
Trust, knowledge sharing, and innovative work behavior: empirical evidence from Poland

PurposeThe purpose of this paper is to assess the effects of two types of trust (vertical and horizontal trust) on knowledge sharing (knowledge donating and knowledge collecting) and the impact of knowledge sharing on innovative work behavior (idea generation and idea realization). The study also explores the mediating role of knowledge sharing.Design/methodology/approachPartial least squares path modeling and data collected from 252 participants at one large Polish capital group were used to test the research hypotheses.FindingsThe results showed that both vertical trust and horizontal trust are positively related to knowledge donating and knowledge collecting. Contrary to knowledge collecting, knowledge donating is significantly related to idea generation, which is highly correlated with idea realization. There is no direct relation between knowledge sharing behavior and idea realization. Knowledge donating mediates the relationship between vertical trust and idea generation.Research limitations/implicationsSelf-reports and the cross-sectional nature of the data collection are the main limitations of this study.Practical implicationsThe results allow managers to better understand what factors and processes contribute to greater employee innovativeness.Originality/valueTo the best of the author's knowledge, the study is the first to examine the relationships among vertical trust, horizontal trust, knowledge donating, knowledge collecting, idea generation and idea realization in an integrated way. This paper answered the questions (1) which type of trust is more important for knowledge sharing, and (2) which type of knowledge sharing behavior is more important for innovative work behavior. This paper investigated whether differences in the strength of relationships between constructs are significant.
Development of Specific Inhibitors for Oncogenic Phosphatase PPM1D by Using Ion-Responsive DNA Aptamer Library

(1) Background: Ser/Thr protein phosphatase PPM1D is an oncogenic protein. In normal cells, however, PPM1D plays essential roles in spermatogenesis and immune response. Hence, it is necessary to develop novel PPM1D inhibitors without side effects on normal cells. Stimuli-responsive molecules are suitable for the spatiotemporal regulation of inhibitory activity. (2) Methods: In this study, we designed an ion-responsive DNA aptamer library based on G-quadruplex DNA that can change its conformation and function in response to monovalent cations. (3) Results: Using this library, we identified the PPM1D specific inhibitor M1D-Q5F aptamer. The M1D-Q5F aptamer showed anti-cancer activity against breast cancer MCF7 cells. Interestingly, the induction of the structural change resulting in the formation of G-quadruplex upon stimulation by monovalent cations led to the enhancement of the inhibitory activity and binding affinity of M1D-Q5F. (4) Conclusions: These data suggest that the M1D-Q5F aptamer may act as a novel stimuli-responsive anti-cancer agent.
POTENTIAL ANTIFUNGAL ACTIVITY OF ESSENTIAL OILS AND THEIR APPLICATION IN FOOD PRESERVATION

The quality of food is highly affected by different types of biological, chemical, and physical contaminants. Microbial contaminations that are transferred through direct or indirect pathways such as through saliva, pest droppings, blood, or fecal matter affect the quality of food worldwide. Food can be spoiled by bacteria as well as fungus. The fungal microbes secrete toxins to intoxicate the food material rendering it unfit for consumption. The objective of the present review is to explore the application of essential oil (EO) as potent antifungal agent and thus good sources of food preservative. We have reviewed previously published papers on antimicrobial activity of EOs. The antimicrobial activity of these natural plant products has been assayed by different approaches. Apart from their activity against microbes, the other beneficial effects of these plant products such as antioxidant activity and enhancing the food quality are also observed by various groups of scientists all over the globe. On the basis of results obtained by different researchers worldwide, the EOs can be authenticated as a food preservative. For the preservation of food, several chemicals are being used by different food industries at large scale; however, they have some limitations. Recently much attention has been directed toward the development of less or negligibly toxic ethno-products which may be utilized for human use for several purposes such as food preservatives, in cosmetics, and medicines. The plant-based volatile EOs and non-volatile secondary metabolites have wide applications in dietary supplements, food flavoring and preservation, folk medicine, and fragrance industry. Several reports have confirmed the antioxidant efficacy of plant-based EOs in vitro and in vivo . Application of plant materials as dietary supplements and preservatives is mainly due to their antioxidant, antimicrobial, and other biological as well as pharmaceutical potentials. Nowadays, EOs and their components are gaining increased attention because of their relatively safe status, their wide acceptance by consumers and the possibility of their exploitation for potential multipurpose uses. It will be relevant to extract EOs, since these extracted oils may have antimicrobial potential which can be utilized for their possible roles against food spoilage microbes.
Robotic 3D Vision-Guided System for Half-Sheep Cutting Robot

Sheep body segmentation robot can improve production hygiene, product quality, and cutting accuracy, which is a huge change for traditional manual segmentation. With reference to the New Zealand sheep body segmentation specification, a vision system for Cartesian coordinate robot cutting half-sheep was developed and tested. The workflow of the vision system was designed and the image acquisition device with an Azure Kinect sensor was developed. Furthermore, a LabVIEW software with the image processing algorithm was then integrated with the RGBD image acquisition device in order to construct an automatic vision system. Based on Deeplab v3+ networks, an image processing system for locating ribs and spine was employed. Taking advantage of the location characteristics of ribs and spine in the split half-sheep, a calculation method of cutting line based on the key points is designed to determine five cutting curves. The seven key points are located by convex points of ribs and spine and the root of hind leg. Using the conversion relation between depth image and the space coordinates, the 3D coordinates of the curves were computed. Finally, the kinematics equation of the rectangular coordinate robot arm is established, and the 3D coordinates of the curves are converted into the corresponding motion parameters of the robot arm. The experimental results indicated that the automatic vision system had a success rate of 98.4% in the cutting curves location, 4.2 s time consumption per half-sheep, and approximately 1.3 mm location error. The positioning accuracy and speed of the vision system can meet the requirements of the sheep cutting production line. The vision system shows that there is potential to automate even the most challenging processing operations currently carried out manually by human operators.
Study on pelagic copepods from Pipnakha Village, district Gujranwala, Pakistan.

Seasonal variations, density and diversity of fresh water copepods were investigated from October 2011 to August 2012. In total, 20 copepod species were identified. Density of copepods was high in spring and low in winter. Mesocyclops edax was the dominant species in summer, monsoon and fall, while Ectocyclops phaleratus and Eucyclops agilis were dominant in winter and spring respectively. Impact of selected physico-chemical parameters on population dynamics of copepods was also studied. Copepods density was positively correlated with temperature, pH, total dissolved solids (TDS) and turbidity and negatively correlated with dissolved oxygen (DO). Shannon-Weaver diversity index, Simpson index, Pielou’s evenness index, and Margalef index were calculated to find out diversity of copepods. Analysis of variance (ANOVA) showed significant difference (F=22.36, P=0.000) in copepods density of all seasons. Principal component analysis (PCA) was used to find out correlation between copepod species and seasons.
Mass Spectrometry OMICS Approach to Study Medicinal Chemical Molecular Responses on Living Organisms

Copyright: © 2015 Meurer EC. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Studies on the effect of drugs on organisms such as plants, animals and human beings have experienced an evolutionary leap in the form of proteomic and metabolomic analysis using mass spectrometry (MS). The 2002, Chemistry Nobel prize winner John Fenn established a landmark in this field by introducing the electrospray ionization technique (ESI), which allows for the transfer of proteins and small biomolecules from solutions to mass spe`ctrometers for MS analysis [1,2]. Since the advent of ESI-MS, a great variety of methodologies have appeared to help scientists in solving important questions on clinical and medicinal chemistry. MS has been now established as the stateof-the-art analytical tool in which richest data from molecular systems can be acquired. In medicinal chemistry, three MS approaches might be highlighted as the most prominent: data dependent UPLC-ESIHRMS metabolomics [3], data dependent nanoLC-nanoESI-HRMS proteomics [4] and MS imaging applied to the biomarker screening of tissues [5].
Quantification of Urokinase Plasminogen Activator (uPA) and Plasminogen Activator Inhibitor Type 1 (PAI-1) mRNA in Breast Cancer Tissue

Urokinase-type plasminogen activator (uPA) and its inhibitor plasminogen activator inhibitor type 1 (PAI-1) play a key role in tumor-associated processes such as the degradation of extracellular matrix proteins, tissue remodeling, cell adhesion, migration, and invasion. High antigen levels of uPA and PAI-1 in tumor tissue of various solid malignant tumors, including breast cancer, are associated with poor patient prognosis. Quantitative real-time PCR (QPCR) assays based on the LightCycler technology were established to quantify uPA and PAI-1 mRNA expression in (breast cancer) cell lines as well as in tumor tissue of breast cancer patients, and was examined as a potential alternative to the measurement of the respective antigen levels. In conclusion, the implementation of mRNA quantification of uPA and PAI-1 in breast tumors is unable to serve as a one-to-one substitution for antigen determination by ELISA.
The Effectiveness of Acupuncture for Dysphagia after Stroke: A Systematic Review and Meta-Analysis

Objectives This study reviewed and evaluated existing evidence of the efficacy of acupuncture as a clinical treatment for dysphagia after stroke. Methods Five English and four Chinese databases were searched from inception to March 2020. All randomized controlled trials (RCTs) incorporating acupuncture or acupuncture combined with other interventions for the treatment of dysphagia after stroke were enrolled. All data were independently assessed and extracted by two authors. The bias risk assessment recommended by the Cochrane Collaboration's tool was used to assess the quality of the selected studies. This meta-analysis was conducted by using RevMan 5.3. Pooled analyses were calculated by the mean difference (MD) and 95% confidence interval (CI). Heterogeneity was assessed by the I2 test. Results Thirty-five studies involving 3024 patients were analyzed. The meta-analysis showed that the therapeutic efficacy of acupuncture combined with other interventions was better than that of the control group for the standardized swallowing assessment (SSA) score (MD = −3.78, 95% CI: −4.64 to −2.91, P < 0.00001), Ichiro Fujishima rating scale (IFRS) score (MD = 1.68, 95% CI: 1.16 to 2.20, P < 0.00001), videofluoroscopic swallowing study (VFSS) score (MD = 2.26, 95% CI: 1.77 to 2.74, P < 0.00001), and water swallowing test (WST) score (MD = −1.21, 95% CI: −1.85 to −0.57, P= 0.0002). In studies reporting adverse effects, no serious outcome from an adverse event was confirmed. Conclusion This systematic review indicated that acupuncture could be an effective therapy for treating dysphagia after stroke although stricter evaluation standards and rigorously designed RCTs are needed.