Miracle-dz/UniFAR-FTUs huggingface dataset:
Meconium Evacuation for Facilitating Feed Tolerance in Preterm Neonates: A Systematic Review and Meta-Analysis

Background: A delayed passage of meconium is considered as a risk factor for feed intolerance in preterm neonates. Objectives: The aim of this study was to review the effects of different therapeutic agents for meconium evacuation on feed tolerance in preterm neonates. Methods: A systematic review of randomised controlled trials (RCTs) of different therapeutic agents for meconium evacuation in preterm neonates (gestation <32 weeks and/or birth weight <1,500 g) using the Cochrane systematic review methodology was undertaken. Databases including Google Scholar were searched in January 2016. The primary outcome was the time to reach full feeds (TFF; ≥120 ml/kg feeds with stoppage of parenteral nutrition >24 h). Secondary outcomes included necrotising enterocolitis (NEC), weight at discharge and adverse effects. The results were summarised as per the GRADE guidelines. Results: Six RCTs (2 each of glycerine suppository and enema, 1 normal saline enema and 1 oral osmotic contrast agent; n = 442) with a low or unclear risk of bias were included. The pooled estimate (random effects model) showed no reduction in TFF [mean difference (MD) -0.03, 95% CI -2.47, 2.41, p = 0.98; level of evidence: low]. No differences in NEC [risk ratio (RR) 1.71, 95% CI 0.63, 4.65, p = 0.30; level of evidence: low] and weight at discharge (MD -0.08, 95% CI -0.30, 0.15, p = 0.50; level of evidence: low) were found. The trial assessing oral osmotic contrast agents reported a trend towards a higher incidence of NEC ≥ stage II. There were no other adverse effects. Conclusion: Limited low-quality evidence indicates that prophylactic glycerine suppository, small volume glycerine/normal saline enema or oral osmotic contrast agents to evacuate meconium did not reduce TFF in preterm neonates. Large, well-designed trials are essential to study this clinically significant issue.
Measuring Poverty for Food Security Analysis

Background: Poverty and food insecurity are intrinsically linked as poor households often lack the resources required to access sufficient nutritious food to live an active and healthy life. Consumption and expenditure surveys are typically used to identify poor versus nonpoor households but are detailed and costly. Measures of wealth based on asset ownership and housing characteristics can be generated from lighter, less costly surveys. Objective: To examine whether indices based on asset ownership and housing characteristics (stock) complement household consumption (flow) when used to analyze inequalities in food security outcomes. Methods: Comprehensive data from Nepal, Malawi, Tanzania, Uganda, and Madagascar are used to examine correlations and overlaps in classification between indices of household wealth and consumption per capita. Inequality in food security indicators representing quantity, quality, and vulnerability is examined across wealth and consumption per capita quintiles. Results: Wealth indices are correlated with consumption per capita, with coefficients between 0.5 and 0.6. The prevalence of food insecurity decreases from poorer to wealthier quintiles for all variables and for all food security measures in all countries. Energy deficiency varies much more across consumption quintiles than wealth index quintiles. Interestingly, inequalities in the share of consumption of food are more pronounced across the wealth index quintiles than per capita consumption. Conclusion: Although wealth indices and consumption per capita are related and both are drivers of food security, they cannot be used interchangeably for food security analysis. Each inequality measure is important for describing different aspects of food security.
Evaluation of positive and negative predictors of seizure outcomes among patients with immune-mediated epilepsy: a meta-analysis

Background: The objective of this study was to analyze published literature on autoimmune epilepsy and assess predictors of seizure outcome. Methods: From PubMed and EMBASE databases, two reviewers independently identified publications reporting clinical presentations, management and outcomes of patients with autoimmune epilepsy. A meta-analysis of 46 selected studies was performed. Demographic/clinical variables (sex, age, clinical presentation, epilepsy focus, magnetic resonance imaging [MRI] characteristics, time to diagnosis and initiation of immunomodulatory therapy, and type of immunomodulatory therapy) were compared between two outcome groups (responders and nonresponders). Clinical response was defined as >50% reduction in seizure frequency. Unstandardized effect sizes were collected for the studies for responder and nonresponder groups. Sample size was used as the weight in the meta-analysis. The random effects model was used to account for heterogeneity in the studies. Results: The 46 reports included 186 and 96 patients in responder and nonresponder groups respectively. Mean age of the responders and nonresponders was 43 and 31 years (p < 0.01). Responders were more likely to have cell-surface antibodies (68% versus 39%, p < 0.05), particularly voltage-gated potassium channel complex antibodies (p < 0.01). Mean duration from symptom onset to diagnosis, and symptom onset to initiation of immunomodulation was significantly lower among the responders (75 versus 431 days, p < 0.05, and 80 versus 554, p < 0.01, respectively). There was no outcome difference based on gender, MRI characteristics, seizure type, type of acute immunomodulatory therapy, or use of chronic immunomodulation. Conclusions: Among published cases to date, older age, presence of cell-surface antibodies, early diagnosis and immunomodulatory treatment are associated with better seizure outcomes among patients with autoimmune epilepsy.
Estimation of the characteristics of a Lévy process observed at arbitrary frequency

A Lévy process is observed at time points of distance Δ until time T. We construct an estimator of the Lévy–Khinchine characteristics of the process and derive optimal rates of convergence simultaneously in T and Δ. Thereby, we encompass the usual low‐ and high‐frequency assumptions and also obtain asymptotics in the mid‐frequency regime.
Towards Live Domain-Speciﬁc Languages From Text Differencing to Adapting Models at Runtime

Live programming is a style of development characterized by incremental change and immediate feedback. Instead of long edit-compile cycles, developers modify a running program by changing its source code, receiving immediate feedback as it instantly adapts in response. In this paper we propose an approach to bridge the gap between running programs and textual Domain-Speciﬁc Languages (DSLs). The ﬁrst step of our approach consists of applying a novel model differencing algorithm, TMDIFF , to the textual DSL code. By leveraging ordinary text differencing and origin tracking, TMDIFF produces deltas deﬁned in terms of the meta model of a language. In the second step of our approach the model deltas are applied at runtime to update a running system, without having to restart it. Since the model deltas are derived from the static source code of the program, they are unaware of any runtime state maintained during model execution. We therefore propose a generic, dynamic patch architecture, RMPATCH , which can be customized to cater for domain-speciﬁc state migration. We illustrate RMPATCH in a case study of a live programming environment for a simple DSL implemented in R ASCAL for simultaneously deﬁning and executing state machines.
Monitoring exercise-induced changes in glycemic control in type 2 diabetes.

PURPOSE The present study determined the efficacy of the Continuous Glucose Monitoring System (CGMS) during moderate exercise and monitored the changes in whole-day glucose profiles using the CGMS in individuals with and without type 2 diabetes. METHODS Six, obese, diet-treated individuals with and four age-matched individuals without type 2 diabetes were monitored using the CGMS for 3 d. Subjects cycled at 90% of a predetermined lactate threshold for 1 h at approximately 09:00 h on day 2, during which venous blood was sampled at 10-min intervals and immediately analyzed for glucose concentrations. RESULTS Venous blood glucose and CGMS values declined during exercise in the diabetes (P < 0.001) but not the control group (P = 0.085). The CGMS overestimated blood glucose in the control (P = 0.003) and the diabetes (P = 0.045) groups during exercise. The number of data points outside of the 95% confidence intervals was <5% in both groups, showing that there is a statistically acceptable level of agreement between venous blood glucose and CGMS values during exercise. Moderate exercise improved whole-day average glucose concentrations (P = 0.007) and whole-day area under the glucose curve (P = 0.016) values (AUCglu), and the time spent within +/-10% of fasting venous glucose (FVG) increased in the diabetes group (P = 0.021). No such effects were seen in the control group. CONCLUSION Using continuous glucose monitoring we were able to demonstrate that a period of moderate exercise improved whole-day glycemic control in obese individuals with type 2 diabetes. The CGMS should only be used as an adjunct and not as an alternative to frequent blood glucose sampling when examining the changes in glucose values during exercise in individuals with and without type 2 diabetes.
Recommenders System for Effective ICT Based Learning

: Recommended Systems for Information & communication technology (ICT-RS) provide personalized services for recommended system. It provides learning objects for teachers and students. User profiling mechanisms are used for recommended system. This paper proposesICT-RSwhich targets to support users in selecting Objects from existing Object Repositories. Automatically constructing their ICT Competence Profiles based on their actions within these ORs. In technology enhanced learning (Tel) major topic is based on user learning profile but not on student learning profile. So in our proposed system teachers and students have equal priority in selecting a Learning objects.
Resolving speech disorders in Parkinson disease: our clinical experience with voice therapy

Introduction: Varying degrees of voice and speech disorders may occur in the course of the Parkinson's disease (PD). Lee Silverman Voice Therapy (LSVT) is a specific method which has been developed for these disorders. Materials and Methods: 15 registered Parkinson's patients of our clinic were enrolled in this study. The stage and the symptoms were evaluated by Unified Parkinson's Disease Rating Scale (UPDRS) and the Hoehn and Yahr (H&Y) staging scale. Voice samples were analysed with the comparison of the mean F0 values (Hz) and voice intensity (dB) levels prior to (pre-therapy) and 3 months after (post-therapy) administration the LSVT. Results: Mean age of the patients were 67.2 ± 12.07 (min (44)-max (86)). There was a statistically significant improvement between the pre-therapy and the post-therapy mean Hz and dB levels (p=0.006 and p 0.05). Conclusions: We aimed to improve our understanding of the importance of non-motor symptoms of the PD such as voice and speech problems. Consistent with the literature, the current study suggests that LSVT is an effective method to manage speech problems of PD.
Population Structure of Phthorimaea operculella (Lepidoptera: Gelechiidae) in the United States

ABSTRACT The potato tuberworm, Phthorimaea operculella Zeller, is one of the most damaging pests of potatoes worldwide. Although tuberworm was recorded in California as early as 1856, it was first reported in damaging numbers in Oregon and Washington in the early 2000s. The objective of this study was to provide baseline information on the population structure of potato tuberworm in the United States. Potato tuberworm adults were collected from potato fields in the major production regions in the United States. Amplified fragment length polymorphisms (AFLP) were used to determine the genetic population structure of potato tuberworm. We used 219 individuals and 335 polymorphic AFLP bands to infer the geographic population structure of potato tuberworm. Posterior probabilities calculated using the model-based clustering method implemented in STRUCTURE, and Fst values calculated using AFLP-SURV confirmed the existence of two distinct populations in the United States (one mostly associated to the western United States and the other one mostly associated to the eastern United States). This study provides baseline data for the molecular characterization of potato tuberworm populations, which will aid in tracking the origin of future invasions within the United States.
Optimal Electromagnetic Design of a Nonsalient Magnetic-Cored Superconducting Synchronous Machine Using Genetic Algorithm

An optimum electromagnetic design of a nonsalient magnetic-cored superconducting synchronous machine (SSM) is presented in this paper. First, self- and mutual inductances of a nonsalient magnetic-cored SSM are calculated using the magnetic energy method and analytical equations of magnetic vector potential. Then, a design approach for an SSM machine is proposed based on the inductances of the machine. An optimal design is finally performed using a genetic algorithm, considering the machine efficiency as an objective function. The finite-element method is utilized in each step to verify the analytical results.
CONSTRUCTIVE INTERFERENCE EXPLOITATION FOR DOWNLINK BEAM FORMING BASED ON NOISE ROBUSTNESS AND OUTAGE PROBABILITY Ka Lung Law

Quality of service (QoS) is commonly measured in terms of sig nal to interference plus noise ratio (SINR), where multiuse r interference is mitigated in order to improve the performance. As opp osed to conventional suppression, interference can be exploite d constructively to enhance the desired signal. With the aid of channel state information (CSI) at the transmitter and data information, we study symbol-level downlink beamforming problems based on noise robustness and outage probability, respectively, subject to power constraints. We further show that an equivalence relationship between the noise robustness and outage probability symbol-level d ownlink beamforming problems can be obtained. Finally, we provide a n analytic symbol error rate (SER) upper bound of the worst user by solving the outage probability-based problem. Our simulations demonstrate that the proposed techniques provide substantial pe rformance improvements over conventional downlink beamforming tech niques.
Inner-Field Guiding Resonator for Efficient Wireless Power Transmission in Proximity Charging Condition

An inner-field guiding resonator (IFGR) is presented for efficient wireless power transmission (WPT) using resonant inductive coupling in proximity charging condition. The IFGR is inserted into a source resonator to obtain a uniform magnetic field distribution which is the important design factor of a proximity WPT system, because it makes the system simple without an adaptive matching technology. As the location of the target resonator changes, the transmission efficiencies are simulated and measured to validate uniform- and high-transmission efficiency. To optimize the WPT system using the IFGR, the design procedure is proposed. Considering the practical WPT system with ground plane, the proximity WPT system including one or two mobile devices was designed and fabricated. The average of the total efficiency at all positions on the source resonator was measured as 82.9% (one mobile device) and 87.1% (two mobile devices), respectively. These results prove that an efficient proximity WPT system can be successfully designed using the IFGR.
System design for a low cost PA-RISC desktop workstation

A low-cost high-performance desktop workstation is described. A high-performance CMOS processor was developed with the specific goal of moving the PA-RISC architecture into the low-cost workstation market. Not only were each of the system components designed for optimal performance, but they were also designed to support the other system components. The processor added features and instructions to improve graphics performance. The memory system was optimized to minimize the effects of cache misses on the CPU performance and at the same time provide the memory to graphics bandwidth needed to support the most advanced graphics systems. Special hardware was added to the memory controller to allow low-cost 3-D graphics systems to be developed. The I/O system provides the most important industry standard I/O interfaces for low cost and high performance, and also provides an industry standard EISA bus for less common and future I/O needs. <<ETX>>
Enriching Topic Modelling with Users' Histories for Improving Tag Prediction in Q&A Systems

The automatic attribution of tags in Question & Answering (Q&A) systems like Stack Exchange can significantly reduce the human effort in tagging as well as improve the consistency among users. Existing approaches typically either rely on Natural Language Processing solely or employ collaborative filtering techniques. In this paper, we attempt to combine the best of both worlds by investigating whether incorporating a personal profile, consisting of a user's history or its social network can significantly improve the predictions of state-of-the-art text-based methods. Our research has found that enriching content-based text features with this personal profile allows to trade-off the precision of predictions for recall and as such improve the "exact match" (predicting the number of tags and the tags themselves correctly) in a multi-label setting from a baseline of 18.2% text-only to 54.3%.
Modified Diffie-Hellman Protocol By Extend The Theory of The Congruence

This paper is introduced a modification to DiffieHellman protocol to be applicable on the decimal numbers, which they are the numbers between zero and one. For this purpose we extend the theory of the congruence. The new congruence is over the set of the real numbers and it is called the “real congruence” or the “real modulus”. We will refer to the existing congruence by the “integer congruence” or the “integer modulus”. This extension will define new terms and redefine the existing terms. As the properties and the theorems of the integer modulus are extended as well. Modified Diffie-Hellman key exchange protocol is produced a sharing, secure and decimal secret key for the the cryptosystems that depend on decimal numbers. Keywords—Extended theory of the congruence, modified DiffieHellman protocol.
The relation between performance of lean Manufacturing and employee' mental workload

The application of lean manufacturing that is so standardized gives negative aspects for a company, such as the possibility of increased mental workload of employees. The purpose of this study is to observe the relation between lean manufacturing performance and employee' mental workload. This research is conducted at an Indonesian aircraft company in division Manufacturing (DPM), Component Assembly (CA), and Final Assembly and Delivery Center (FD). To assess the implementation of lean manufacturing at the company, lean manufacturing benchmarks questionnaire that has been validated into Indonesian is used. Three lean manager in each division fulfill the lean manufacturing benchmark questionnaire. For the measurement of mental workload, the Raw-NASA-TLX is used. 30 operators in each division is participated by fulfilling the raw NASA-TLX questionnaire. Nonparametric statistics showed no significant correlation between the lean manufacturing performance and mental workload. Moderate mental workload in each division is found related with lean manufacturing implementation.
Association between COX-2 G-765 C polymorphism and the risk of Alzheimer ’ s disease : a meta-analysis

Background and object: The morbidity rate of Alzheimer’s disease (AD) has been increasing with the progression of population aging globally, so the burden of the disease is showing an upward tendency. During the research on AD, COX-2 gene G-765C polymorphism has been explored its function in the susceptibility to this disease, but no consensus was reached. Therefore, we performed this meta-analysis with the hope of obtaining a clearer opinion on this topic. Methods: 7 eligible articles were retrieved from online databases. Odds ratios (ORs) and their 95% confidence intervals (95% CIs) were calculated to assess the strength of the association between COX-2 gene G-765C polymorphism and AD susceptibility. Inter-study heterogeneity was inspected with Q test, and sensitivity analysis was performed to verify the stability of pooled results. Additionally, publication bias between included studies was detected using both Begg’s funnel plot and Egger’s test. Results: COX-2 gene G-765C polymorphism decreased the risk of AD under five genetic comparisons of CC vs. GG, CC+GC vs. GG, CC vs. GG+GC, C vs. G and GC vs. GG, and a similar trend was also revealed in Caucasian and other-ethnicity groups after stratification analysis of ethnicity under corresponding contrasts. Conclusion: The C allele of the G-765C polymorphism in the COX-2 gene may provide protection against AD onset.
Comparison of Saffron versus Fluoxetine in Treatment of Mild to Moderate Postpartum Depression: A Double-Blind, Randomized Clinical Trial

Abstract Introduction: Postpartum depression is a common mental health problem that is associated with maternal suffering. The aim of this double-blind clinical trial was to compare safety and efficacy of saffron and fluoxetine in treatment of mild to moderate postpartum depression. Methods: This was a 6-week, double-blind, randomized clinical trial. Subjects were women aged 18–45 years with mild to moderate postpartum depression who had Hamilton Depression Rating Scale (HDRS 17-item) score≤18. Eligible participants were randomized to receive either a capsule of saffron (15 mg capsule) or fluoxetine (20 mg capsule) twice daily for 6 weeks. The primary outcome measure was to evaluate efficacy of saffron compared to fluoxetine in improving depressive symptoms (HDRS score). Results: There was no significant effect for time×treatment interaction on HDRS score [F (4.90, 292.50)=1.04, p=0.37] between the 2 groups. 13 (40.60%) patients in the saffron group experienced complete response (≥50% reduction in HDRS score) compared with 16 (50%) in the fluoxetine group and the difference between the 2 groups was not significant in this regard (p=0.61). Frequency of adverse events was not significantly different between the treatment groups. Discussion: The results of this study may suggest that saffron is a safe alternative medication for improving depressive symptoms of postpartum depression. Nevertheless, it should be mentioned that the trial is not well powered and should be considered a preliminary study. Therefore, large clinical trials with longer treatment periods and comparison with placebo group would be appropriate for future studies.