Miracle-dz/UniFAR-FTUs huggingface dataset:
Novel NIR-Phosphorescent Ir(III) Complexes: Synthesis, Characterization and Their Exploration as Lifetime-Based O2 Sensors in Living Cells

A series of [Ir(N^C)2(N^N)]+ NIR-emitting orthometalated complexes (1–7) has been prepared and structurally characterized using elemental analysis, mass-spectrometry, and NMR spectroscopy. The complexes display intense phosphorescence with vibrationally structured emission bands exhibiting the maxima in the range 713–722 nm. The DFT and TD DFT calculations showed that the photophysical characteristics of these complexes are largely determined by the properties of the metalating N^C ligands, with their major contribution into formation of the lowest S1 and T1 excited states responsible for low energy absorption and emission, respectively. Emission lifetimes of 1–7 in degassed methanol solution vary from 1.76 to 5.39 µs and show strong quenching with molecular oxygen to provide an order of magnitude lifetime reduction in aerated solution. The photophysics of two complexes (1 and 7) were studied in model physiological media containing fetal bovine serum (FBS) and Dulbecco’s Modified Eagle Medium (DMEM) to give linear Stern-Volmer calibrations with substantially lower oxygen-quenching constants compared to those obtained in methanol solution. These observations were interpreted in terms of the sensors’ interaction with albumin, which is an abundant component of FBS and cell media. The studied complexes displayed acceptable cytotoxicity and preferential localization, either in mitochondria (1) or in lysosomes (7) of the CHO-K1 cell line. The results of the phosphorescence lifetime imaging (PLIM) experiments demonstrated considerable variations of the sensors’ lifetimes under normoxia and hypoxia conditions and indicated their applicability for semi-quantitative measurements of oxygen concentration in living cells. The complexes’ emission in the NIR domain and the excitation spectrum, extending down to ca. 600 nm, also showed that they are promising for use in in vivo studies.
Masculinized Faces are Perceived as More Dangerous but Are Not More Memorable

Research shows that faces manipulated to appear more masculine are perceived as more dominant; however, these experiments have relied on forced-choice paradigms, which are susceptible to demand characteristics - situational aspects of the experiment that influence subject behavior towards the expected outcome. We addressed the problems of force-choice paradigms and improved upon a previous investigation by presenting individual faces for a longer duration, and by having men and women rate presented masculinized and feminized faces on their threat potential. Forty-eight participants (25 men) completed a face rating and recognition memory task. Facial photographs were morphed by ± 75% to create masculinized and feminized versions. Participants rated 40 morphed facial photographs (masculinized = 20, feminized = 20) on how dangerous each man would be if he was provoked. To control exposure time for the recognition memory phase, participants viewed each face in the rating phase for five seconds. Following the rating phase, participants completed a recognition memory phase in which they viewed another set of 40 faces (50% new, 50% old, 50% masculinized, 50% feminized). Participants indicated whether each face was ‘old’ or ‘new’ and rated how confident they were in their classification. We predicted higher danger ratings for masculinized faces and greater sensitivity for them in the recognition memory test. In line with our predictions, both men and women assigned higher threat ratings to masculinized men’s faces; however, they did not demonstrate greater sensitivity for masculinized men’s faces or greater confidence in their ratings.
Comparative Insights into the Skin Beneficial Properties of Probiotic Lactobacillus Isolates of Skin Origin

In recent times, probiotics have been emerging as one of valuable cosmetic resources. This work was undertaken to evaluate and compare the skin beneficial properties of three Lactobacillus strains, namely, L. plantarum SB202, L. fermentum SB101, and L. paraplantarum SB401, originally isolated from the healthy skins of Koreans. The Lactobacillus isolates were individually grown in MRS broth, and the corresponding cell-free conditioned mediums (CMs), LP202, LF101 and LPP401, were prepared for analyzing diverse cosmetic potentials at a comparative perspective. The superoxide radical and nitrite ion scavenging activities of the CMs were in the orders of LPP401 ≥ LF101 > LP202 and LPP401 > LF101≒LPP202, respectively. They attenuated the lipopolysaccharide-induced reactive oxygen species (ROS) and nitrite ion levels in RAW264.7 murine macrophages both in the order of LPP401 ≥ LF101 > LP202, implying their anti-inflammatory properties. They exhibited antityrosinase activities in the order of LPP401 > LF101 ≥ LP202 and diminished α-melanocyte-stimulating hormone-induced melanin levels in B16F10 melanoma cells in the order of LPP401≒LF101 > LP202, suggesting their skin whitening activities. They enhanced cornfield envelope formation in HaCaT keratinocytes in the order of LPP401 > LF101 > LP202. They inhibited the in vitro hyaluronidase and elastase activities in the orders of LPP401 > LP202 ≥ LF101 and LPP401 ≥ LP202 > LF101, respectively. Their enhancing properties on the synthesis of procollagen type I in normal human dermal fibroblasts were in the order of LF101≒LPP401 > >LP202. The CMs possess various cosmetic characteristics, such as antioxidant, skin whitening, antiaging, barrier improving, and anti-inflammatory activities. LPP401, the CM prepared from L. paraplantarum SB401, has been evaluated to be more desirable cosmetic resource than LP202 and LF101.
Extrinsic and intrinsic factors influencing the emergence and return of the Asian particolored bat Vespertilio sinensis to the summer roost

Abstract Circadian rhythms play a crucial role in the health and survival of organisms. However, little is known concerning how intrinsic and extrinsic factors affect animal daily rhythms in the field, especially in nocturnal animals. Here, we investigated the first emergence, mid‐emergence, and return times of Vespertilio sinensis, and also integrated environmental conditions (temperature, humidity, and light intensity) and biotic factors (reproductive status and predation risk) to determine causes of variation in the activity rhythms of the bats. We found that variation in the first emergence time, the mid‐emergence time, and the final return time were distinct. The results demonstrated that the emergence and return times of bats were affected by light intensity, reproductive status, and predation risk in a relatively complex pattern. Light intensity had the greatest contribution to activity rhythms. Moreover, we first investigated the effects of actual predators on the activity rhythms of bats; the results showed that the mid‐emergence time of bats was earlier as predators were hunting, but the final return time was later when predators were present. Finally, our results also highlighted the importance of higher energy demands during the lactation in bats to variation in activity rhythms. These results improve our understanding of the patterns and causes of variation in activity rhythms in bats and other nocturnal animals.
The research of near field acoustical holographic imaging method

This paper reviews the theoretical analysis of the imaging method and characteristic of the Nearfield Acoustical Holography (NAH). We present a new filtering method, least squares method for filtering with restraint, which improves the stability of the reconstruction. The computer simulation experiment for the vibration and radiation of a round plate by means of the numerical method of NAH has been done and the effect of the new filtering method has been verified. The NAH imaging of radiation of a small loudspeaker using a scanning linear receiving array of 32 elements has been made and the preliminary results are given in the paper.
Discussion on method for calculating general safety factor of underground caverns based on strength reduction theory

The safety of underground caverns is a key problem of large substructure work for designer. A new method to calculate the general safety factor of underground multi-cavern is put forward,which is based on the strength reduction technique. The method adopts the Mohr-Coulomb rule as the strength yield criterion and takes the transfixion of equivalent plastic strain in wall rock between caverns as the critical failure criterion of caverns. By reducing rock material strength parameters(cohesion c and friction angle φ) step by step,the general safety of caverns is obtained when the result of simulated excavation shows that the equivalent plastic strain of wall rock becomes transfixion,which is the critical state of caverns destabilization. In the course,the calculation program trends to emanate and the deformation of wall rock also tends to rise suddenly and sharply also. The Laxiwa underground hydropower plant,a large cavern group in the northwest China,consists of main powerhouse,auxiliary powerhouse,main transformer chamber,caudal shiplock chamber,tailrace tunnels,and so on. The high geostress and interaction of caverns lead to very serious stability problem. Using the underground caverns strength reduction technique,the general safety factor of Laxiwa underground caverns is gained,which is 1.45. The assistant tunnels of Jinping II hydropower plant are important tunnels also. The general safety factor,calculated by the method,is 1.73. Both of them prove that the method of underground caverns strength reduction technique is very useful for analyzing the general stability of caverns and design of substructure quantitatively.
Systematic Review on Missing Data Imputation Techniques with Machine Learning Algorithms for Healthcare

Missing data is one of the most common issues encountered in data cleaning process especially when dealing with medical dataset. A real collected dataset is prone to be incomplete, inconsistent, noisy and redundant due to potential reasons such as human errors, instrumental failures, and adverse death. Therefore, to accurately deal with incomplete data, a sophisticated algorithm is proposed to impute those missing values. Many machine learning algorithms have been applied to impute missing data with plausible values. However, among all machine learning imputation algorithms, KNN algorithm has been widely adopted as an imputation for missing data due to its robustness and simplicity and it is also a promising method to outperform other machine learning methods. This paper provides a comprehensive review of different imputation techniques used to replace the missing data. The goal of the review paper is to bring specific attention to potential improvements to existing methods and provide readers with a better grasps of imputation technique trends.
Design of a cure monitoring system for composite aircraft repair patches

Aircr& repair patches make use of thermosetting polymers and the quality of the repair depends on proper curing. The design of a cure monitoring system for aircraft repair patches is explored. Cure monitoring was achieved by measuring the signal strength and tirne of flight of an ultrasonic wave transmitted through the material. Custom traasducers, electronics and software was designed for the system. Preliminary resuits were encouraging. The present system does not provide accurate measurements of time of flight and thus cm not provide a quantitative assessrnent of the material properties. However, qualitative results based on changes in signai strength provided important information regarding the state of cure of the thermoset. Several cure tests accompanied by mechanical tests demonstrated the usefulness of the present system. Recornmendations for creating a commercially viable system are given. The system was used to evaluate the practicality of Bragg grathg fibre optic sensors as cure monitoring devices. Bragg gratings do not appear to produce useful cure related data.
Optimized Design of LCL Filter for Minimal Damping Power Loss

As to the problem of LCL filter instability and loss conducted by current harmonics,the relational expression between inductance ratio,damping resistor and resonant frequency,harmonic attenuation ratio,as well as damping power loss was deduced.Based on this,an optimized filter design scheme was proposed which warrants a minimal damping power loss with a needed filtering performance.The optimization can reduce the inductance value and power loss,especially in large-or medium-power applications.Feasibility and effectiveness of the optimized scheme are validated by simulation and experimental results.
Asteroid 2008 TC3, not a polymict ureilitic but a polymict C1 chondrite parent body? Survey of 249 Almahata Sitta fragments

On October 7, 2008, the asteroid 2008 TC3 exploded as it entered the Earth’s atmosphere, producing significant dust (in the atmosphere) and delivering thousands of stones in a strewn field in Sudan, collectively known as the Almahata Sitta (AhS) stones. About 600 fragments were officially recovered in 2008 and 2009. Further rocks were collected since the fall event by local people. From these stones, 249 were classified at the Institut für Planetologie in Münster (MS) known as MS‐xxx or MS‐MU‐xxx AhS subsamples. Most of these rocks are ureilitic in origin (168; 67%): 87 coarse‐grained ureilites, 60 fine‐grained ureilites, 15 ureilites with variable texture/mineralogy, four trachyandesites, and two polymict breccias. We identified 81 non‐ureilitic fragments, corresponding to 33% of the recovered samples studied in Münster. These included chondrites, namely 65 enstatite chondrites (43 EL; 22 EH), 11 ordinary chondrites (OC), one carbonaceous chondrite, and one unique R‐like chondrite. Furthermore, three samples represent a unique type of enstatite achondrite. Since all AhS stones must be regarded as individual specimens independent from each other, the number of fresh ureilite and enstatite chondrite falls in our meteorite collections has been increased by several hundred percent. Overall, the samples weigh between <1 and 250 g and have a mean mass of ~15 g. If we consider—almost 15 years after the fall—the mass calculations, observations during and after the asteroid entered the atmosphere, the mineralogy of the C1 stones AhS 91A and AhS 671, and the experimental work on fitting the asteroid spectrum (e.g., Goodrich et al., 2019; Jenniskens et al., 2010; Shaddad et al., 2010), the main portion of the meteoroid was likely made of the fine‐grained (carbonaceous) dust and was mostly lost in the atmosphere. In particular, the fact that C1 materials were found has important implications for interpreting asteroid 2008 TC3's early spectroscopic results. Goodrich et al. (2019) correctly suggested that if scientists had not recovered the “water‐free” samples (e.g., ureilites, enstatites, and OC) from the AhS strewn field, 2008 TC3 would have been assumed to be a carbonaceous chondrite meteoroid. Considering that the dominating mass of the exploding meteoroid consisted of carbonaceous materials, asteroid 2008 TC3 cannot be classified as a polymict ureilite; consequently, we state that the asteroid was a polymict carbonaceous chondrite breccia, specifically a polymict C1 object that may have formed by late accretion at least 50–100 Ma after calcium–aluminum‐rich inclusions.
Investigation on Characterization of Typical Characteristic in Compressor Based on Flat Plate Model

The acoustic resonance of aero-engine compressors is very harmful, which can lead to the failure of components such as blades. The mechanism of acoustic resonance is very complicated. To solve this problem, characteristics of the noise signal under the abnormal vibration state of the rotor blade are analyzed through the noise measurement in the compressor in the paper. The frequency spectrum characteristics, sound pressure level, and phase relationship of the noise signal corresponding to the abnormal vibration of the rotor blade are captured, and the feature of “frequency locked” which is consistent with the acoustic resonance in the compressor is obtained. Numerical simulation is a better way to study the mechanism of acoustic resonance. Therefore, based on the Parker model, a research method of acoustic resonance characteristics and mechanism based on acoustic analogy is proposed from the solution of the sound-induced in the pipe cavity. The vortex system and sound field characteristics when the acoustic resonance occurs are calculated. The results show that the distribution characteristics of the shedding vortex can be recognized, which are consistent with the experimental results of Welsh when the acoustic resonance occurs. The error of the acoustic resonance frequency from numerical simulation results to experimental is 3.6%. The characteristic of “frequency locked” and Parker β mode of the acoustic resonance is captured. The acoustic analogy method is suitable for the characterization of the acoustic resonance performance and mechanism in the pipeline and in the aeroengine compressor.
The digital literacies of early childhood educators: perceptions of collaborative online learning

ABSTRACT This explanatory mixed methods study investigated the role digital literacies play in the collaborative online learning of early childhood educators (ECEs). Through reporting quantitative survey and qualitative interview data, study results describe the attitudes and skills that contribute to ECEs’ abilities to fluently use different modes of technology to participate in collaborative online learning. Both ECEs’ and Instructors’ (higher education professionals facilitating ECE online learning courses) perceptions contribute to results on what supports and components are imperative for initial and sustained success regarding ECEs traversing and engaging with current technologies. Based on integration of databases and analysis of study results, recommendations are offered on how online learning can be used to develop the digital literacies of ECE online students.
Vitamin D Status Assessment: Lack of Correlation between Serum and Hair 25-Hydroxycholecalciferol Levels in Healthy Young Adults

Vitamin D deficiency has been linked to numerous health problems, including those resulting from disturbed calcium-phosphorus homeostasis, and neuropsychiatric and autoimmune disorders. Nearly one-third of the global population has suboptimal levels of vitamin D, according to epidemiological data. Vitamin D status is usually determined by measuring serum 25(OH)D, but, for decades, serum 25(OH)D measurement has been hampered by a lack of standardization. There have been many recent initiatives to develop reference substances and methods for measuring vitamin D and its metabolites, and re-evaluating the optimal values. It was also suggested that alternative biological samples could also be used, such as hair, since it has been established that lipophilic substances, such as corticosteroids, can also be found in hair. The purpose of this study was to determine the correlation between 25(OH)D3 concentrations in serum and hair, and other demographic features in 26 healthy Caucasian young adult volunteers. The determination of 25(OH)D3 and cholecalciferol was carried out using liquid chromatography coupled with mass spectrometry (LC-MS) from blood and hair samples taken at two timepoints separated by nine weeks. In the hair samples of 18 out of 26 subjects, 25(OH)D was detected at a mean (±SEM) concentration of 17.07 ± 5.375 pg/mg at the first sampling time, and 58.90 ± 25.97 pg/mg at the second sampling time. A multiple linear regression analysis revealed no effects of gender, body mass index, supplementation, or sun exposure on hair 25(OH)D3 concentrations, but supplementation and sun exposure significantly increased serum 25(OH)D3 concentrations. In addition, serum and hair 25(OH)D3 concentrations did not correlate; however, there was a strong correlation between the two sampling times for serum 25(OH)D3 concentrations. In conclusion, this study confirmed that 25(OH)D3 could be detected in human hair, but its use as a biomarker warrants further investigations since no link was found between serum 25(OH)D3 concentrations, supplementation, sun exposure, and hair 25(OH)D3 concentrations levels.
Targeted and Untargeted Mass Spectrometry-Based Metabolomics for Chemical Profiling of Three Coffee Species

While coffee beans have been studied for many years, researchers are showing a growing interest in coffee leaves and by-products, but little information is currently available on coffee species other than Coffea arabica and Coffea canephora. The aim of this work was to perform a targeted and untargeted metabolomics study on Coffea arabica, Coffea canephora and Coffea anthonyi. The application of the recent high-resolution mass spectrometry-based metabolomics tools allowed us to gain a clear overview of the main differences among the coffee species. The results showed that the leaves and fruits of Coffea anthonyi had a different metabolite profile when compared to the two other species. In Coffea anthonyi, caffeine levels were found in lower concentrations while caffeoylquinic acid and mangiferin-related compounds were found in higher concentrations. A large number of specialized metabolites can be found in Coffea anthonyi tissues, making this species a valid candidate for innovative healthcare products made with coffee extracts.
Humility and Competence: Which Attribute Affects Social Relationships at Work?

Between likability and competence, people value likable colleagues (regardless of their competence level) more than competent colleagues. If humility replaces competence, the preference might be different since humility is not always associated with positive outcomes. Humility and competence form four archetypes: humble star, humble fool, competent jerk, and incompetent jerk. This study examined the personal and professional preferences for these archetypes in the workplace and how the preference is moderated by colleagues’ seniority. There were 475 working adults aged between 21 and 77 (M = 40.34, SD = 11.32) recruited to complete an online survey. While humble fools were more likable than competent jerks in personal interactions, competent jerks received more cooperation than humble fools in professional interactions. Seniority did not affect these findings. Our findings shed light on whether, and when, humility should be highly valued in organizational settings. Promoting humility in the workplace setting might require more caution.
The impacts of armed conflicts on prenatal and delivery care utilization

ABSTRACT This study investigates the extent to which exposure to armed conflicts during pregnancy influences women’s utilization of prenatal and delivery care in 35 developing countries between 1990 and 2018. Exploiting the variation across residential districts and conception months-years in a difference-in-differences framework, we find that women exposed to armed conflicts during pregnancy tend to receive insufficient prenatal and delivery care evident by the declines in the composite indices of Prenatal Care and Delivery Care by 6.76 and 6.83% compared to the sample averages, respectively. Given the importance of prenatal care and delivery care to the health of mothers and newborns, our findings call for effective interventions to support mothers and babies during and after conflicts.