Miracle-dz/UniFAR-FTUs huggingface dataset:
The herpes simplex virus 1 Us3 kinase is involved in assembly of membranes needed for viral envelopment and in distribution of glycoprotein K

Background : Capsids of herpes simplex virus 1 (HSV-1) are assembled in cell nuclei, released into the perinuclear space by budding at the inner nuclear membrane acquiring tegument and envelope. Alternatively, capsids gain access to the cytoplasm via dilated nuclear pores. They are enveloped by Golgi membranes. Us3 is a non-essential viral kinase that is involved in nucleus-to-cytoplasm translocation, preventing apoptosis and regulation of phospholipid-biosynthesis. Us3-deletion mutants (HSV-1∆Us3) accumulate in the perinuclear space. Nuclear and Golgi membranes proliferate, and homogeneous, proteinaceous structures of unknown identity are deposited in nuclei and cytoplasm. Glycoprotein K (gK), a highly hydrophobic viral protein, is essential for production of infectious progeny virus but, according to the literature, exclusively vital for envelopment of capsids by Golgi membranes. In the absence of Us3, virions remain stuck in the perinuclear space but mature to infectivity without reaching Golgi membranes, suggesting further function of gK than assumed. Methods : We constructed a HSV-1∆Us3 mutant designated CK177∆Us3gK-HA, in which gK was hemagglutinin (HA) epitope-tagged in order to localize gK by immunolabeling using antibodies against HA for light and electron microscopy. Results : CK177∆Us3gK-HA-infected Vero cells showed similar alterations as those reported for other HSV-1∆Us3, including accumulation of virions in the perinuclear space, overproduction of nuclear and Golgi membranes containing electron dense material with staining property of proteins. Immunolabeling using antibodies against HA revealed that gK is overproduced and localized at nuclear membranes, perinuclear virions stuck in the perinuclear space, Golgi membranes and on protein deposits in cytoplasm and nuclei. Conclusions : Us3 is involved in proper assembly of membranes needed for envelopment and incorporation of gK. Without Us3, virions derived by budding at nuclear membranes remain stuck in the perinuclear space but incorporate gK into their envelope to gain infectivity.
Trait Theory , and Collaboration in Telemedicine : A Circumplex Perspective

More than a process-automating tool, telemedicine is increasingly recognized for its ability to facilitate collaboration and knowledge creation between disparate healthcare providers. As trust is being demonstrated to affect positively the collaborative effort of practitioners and the concomitant, as well as subsequent impact on quality of health care delivery [1], the questions arise, What are the interpersonal traits of practitioners that contribute to a constructive and continuing telemedicine-centered collaboration? Furthermore, how do these interpersonal traits translate into specific types of interactions that maximize telecollaboration? These questions are especially germane as much telemedicine equipment remains underutilized, and administrators concern themselves with sustainability. Previous work has largely centered on relational variables affecting trust in collaboration, such as competence, reputation, and trustworthiness, but has neglected the personal characteristics that might impact participants’ proclivity to collaborate and trust. This paper introduces the circumplex model as a framework for understanding the development of trust in collaborative telemedicine. The circumplex posits that interpersonal interaction can be explained along the two dimensions of power and affiliation. Sixteen personality traits may be arrayed in a circular or clockwise fashion around the psychological axis of Dominance and Nurturance [2], [3]. Recent causal modeling studies of the relational relationships between the dimensions of the circumplex theory of interpersonal interaction and measures of interpersonal trust have found that the circumplex dimensions of Dominance and Nurturance are significant positive predictors of interpersonal trust [4], [5]. Understanding these interpersonal characteristics of individuals may help address the constraints impeding telemedicine usage.
DFIG wind turbine under unbalanced power system conditions using adaptive fuzzy virtual inertia controller

The Doubly-Fed Induction Generator (DFIG) based Wind Turbines Generator (WTG) with traditional Maximum Power Point Tracking (MPPT) control provides no inertia response under system frequency events. Recently, the DFIG wind turbines have been equipped with the Virtual Inertia Controller (VIC) to enhance the frequency stability of the power system. However, the conventional VICs with fixed gain have negative effects on the inter-area oscillations of regional networks. To cope with this drawback, this paper proposes a novel adaptive VIC to improve both the inter-area oscillations and frequency stability. In the proposed scheme, the gain of the VIC is dynamically adjusted using fuzzy logic. The effectiveness and control performance of the adaptive fuzzy VIC is evaluated under different frequency events such as loss of generation and three-phase fault with load shedding. The simulation studies are performed on a generic two-area network integrated with a DFIG wind farm, and the comparative results are presented for these three cases: DFIG without VIC, DFIG with fixed gain VIC, and DFIG with adaptive fuzzy VIC. The results confirm the ability of the proposed adaptive fuzzy VIC in improving both the interarea oscillations and frequency stability of the system.
Polarization Bistability in 1550 nm Wavelength Single-Mode Vertical-Cavity Surface-Emitting Lasers Subject to Orthogonal Optical Injection

In this paper, we report on an experimental investigation of the bistable behavior of a 1550 nm single transverse and polarization mode vertical-cavity surface-emitting laser (VCSEL) when subjected to orthogonal optical injection. As the master laser wavelength is scanned near the resonance wavelength of the depressed linearly polarized fundamental mode, and for a fixed injected power, the VCSEL exhibits two successive polarization switchings (PSs). Both PSs exhibit bistable regions in such a way that a pure-frequency-induced polarization bistability is found. The width of both bistable regions has been measured as a function of the injected power and for different values of the VCSEL current. While the injection power is lesser than a certain value, the hysteresis width fluctuates around a constant level. Further increase of the injection power leads to a smaller constant value of the hysteresis width. The value of that transition value is independent of the VCSEL current. Power-induced polarization bistability - by fixing the master laser wavelength - is found near the transition value. Clockwise and anticlockwise power-hysteresis cycles are observed for short and long master laser wavelengths, respectively.
Humen Security System using Arduino GPS and GSM

:- The world is becoming unsafe for Humen in all aspects. The crimes against Humen are increasing at a higher rate.The employed Humen are feeling unsafe due to increasing crimes. This paper proposes a quick responding mechanism that helps Humen during trouble. When someone is going to harass, she can press the button that is attached to the device and the location information is sent as an SMS alert to few pre defined emergency numbers in terms of latitude and longitude. The microcontroller used is PIC16877A. It is interfaced with a push button, a GPS module, a GSM modem and a speech circuit (ISD1820PY). If the switch is pressed, it activates the speech circuit to capture the attention of the people nearby for help. The program is developed in embedded language to demonstrate the system capability in providing real time response. Thus the girl can be safe and she can feel protected.
Maryland’s Forest Conservation Act and the Impact on Residential Development and Forest Cover Change

We analyze the effects of a unique forest conservation regulation on residential development and assess the additionality in forest cover due to this regulation. We combine panel data on forest cover change from satellite imagery and parcel-level modeling on residential development, including residential subdivisions occurring before and after regulation adoption. Our results indicate that after introducing the regulation, there was a 22% increase in forest cover within subdivisions relative to the amount without the regulation. The heterogeneous effects of this regulation suggest that forest cover increased on average for parcels with lower levels of existing forest cover. However, parcels with the highest levels of forest cover continue to have significant decreases in forest cover, despite the regulation, thereby resulting in fragmentation in regions with the most intact forest cover.
KINETICS OF LEACHING PROCESS OF SELLA URANIUM ORE MATERIAL, SOUTH EASTERN DESERT, EGYPT

The leaching of uranium from Sella uranium ore using hydrochloric acid solution has been studied. The effect of different parameters such as leaching time, hydrochloric acid concentration, liquid/ solid mass ratio, reaction temperature, mechanical stirring speed are investigated in order to optimize various process parameters for maximizing the recovery of uranium. The maximum percentage uranium leaching of 96 % is achieved after 15 min of contact time leaching using 3.0 M hydrochloric acid and 4/ 1 liquid/ solid mass ratio at 26 °C with 400 rpm mechanical stirring speed. The experimental data are well interpreted with a shrinking core model with diffusion control through a porous product layer. By using the Arrhenius expression, the apparent activation energy for the uranium leaching reaction is evaluated.
Developing Healthy Environment for Young Mothers in Suburb Indonesia

This article explores community services approach that intends to change the behavior of young mothers at home in serving food for their families. Research results showed that there were challenges in this suburb area. , especially for young mother who can get many facilities to get their daily meals. Unfortunately, the facilities could give negative impacts on them in gaining proper nutrition. The obstacles came from many aspects of society. Thereupon, social intervention for them needs to be handled carefully so that the beneficiaries could get sustainable change. Others have argued that participation is crucial elements in community intervention. This research showed that participation its self is the hard aspect in the suburb especially at the region that has rapid development but lack of social investments. People used to get many projects from different organizations. The helping projects often did not consider sustainability matters. This condition reshapes the people. They become the object of social programs. Maintaining intensive programs based on some practices: collaboration planning and implementation could increase the trust of the beneficiaries. Based on our study on ten young women and other fourteen participants in a suburb of Indonesia, trust is primary material in changing people’s behavior. Especially educating people to live in healthy lifestyle as a vital aspect of developing a healthy environment.
Mahgoub Deterioration Method and its Application in Solving Duo-combination of Nonlinear PDE’s

This paper aims to solve Duo-combination of non linear partial differential equations by a latest approach called Mahgoub deterioration method (MDM). The latest technique is mix of the Mahgoub transform furthermore the, Adomian deterioration method. The generalized solution has been proved. Mahgoub deterioration method (MDM) is a very successful tool for finding the correct solution of linear and non linear partial differential equations. The continuance and uniqueness of solution is based on MDM.
Serotonin receptor subtypes : basic and clinical aspects

Molecular Characterization of Three Serotonin Receptor Subtypes Medical Chemistry of Serotonergic Agents The Molecular Pharmacology of 5-Hydroxytryptamine Receptor Subtypes Biochemistry of 5-Hydroxytryptamine Receptor Subtypes: Coupling to Second Messenger Systems The Electrophysiology of Serotonin Receptor Subtypes Serotonin Neurotoxins: Focus on MDMA (3,4- Methylenedioxymethamphetamine, "Ecstasy") Serotonin and Animal Behaviour The Clinical Utility of Serotonin Receptor Active Agents in Neuropsychiatric Disease.
Examination of Problem Solving Skills Among University Students with Childhood Trauma Experiences

Objective: Problem solving skills are an important subject to handle with childhood trauma experiences. The aim of this study was to examine problem solving skills with childhood trauma experiences among university students. Methods: Participants consist of 647 students from a Faculty of Education. The Problem Solving Inventory, Childhood Trauma Questionnaire (CTQ) and Sociodemographic Form were administered to the students to collect data. Childhood Trauma Questionnaire scores were calculated as the low and high level of childhood trauma experiences. The independent samples t-test was used to assessment data. Results: There were statistically significant differences between the means of Problem Solving subscale scores (impulsive style, reflective style, avoidant style, monitoring style, confidence style and planfulness style) of the students with the low and high level of childhood trauma (physical, emotional and sexual). Also, the students with both high level of childhood trauma experiences (n=47) and history of suicidal behavior use avoidant style (t=-2.978, p<0.004) and reflective style (t=-2.289, p<0.026) as problem solving skills. Conclusions: The results showed that the students with high childhood trauma experiences are different according to problem solving skills from the students with low childhood trauma experiences. Therefore, improving the problem solving skills in risk groups who are high childhood traumatic experiences is important to well being, to protect from health-damaging and life-threatening behavior.
Stuck-at-Fault Tolerant Schemes for Memristor Crossbar Array-Based Neural Networks

In this study, a circuit technique and training algorithm that minimizes the effect of stuck-at-faults (SAFs) within a memristor crossbar array of neural networks (NNs) are presented. To improve the network performance in the presence of SAFs, a conventional transimpedance amplifier, which is used for summing the currents that flow through the memristors, is modified to ensure that the amplifier output is within the appropriate operating range. Further improvement in the network performance is achieved by using the proposed training algorithm, which utilizes the locations and values of faulty memristors for network training. A feedforward NN employing $32 \times 32$ memristor crossbar arrays is implemented to verify the performance improvement in the NNs using the proposed circuit technique and training algorithm.
Development of Multi-branch T-spline Templates and its Applications in Reverse Engineering

T-Spines are being increasingly used for the design and analysis of complex-shaped geometry. It has numerous potential applications in reverse engineering. In this paper, single and multi-branch T-spline templates have been developed for the reconstruction of tree branches. The proposed method uses crosssections, derived from point cloud data to create T-spline based surface models. We can apply it in reverse engineering for the reconstruction of any single or multibranch object.
An Effective Clustering Method over CF$^+$+ Tree Using Multiple Range Queries

Many existing clustering methods usually compute clusters from the reduced data sets obtained by summarizing the original very large data sets. BIRCH is a popular summary-based clustering method that first builds a CF tree, and then performs a global clustering using the leaf entries of the tree. However, to the best of our knowledge, no prior studies have proposed a global clustering method that uses the structure of a CF tree. Therefore, we propose a novel global clustering method ERC (effective multiple range queries-based clustering), which takes advantage of the structure of a CF tree. We further propose a CF $^+$ + tree, which optimizes the node split scheme used in the CF tree. As a result, the CF $^+$ + -ERC (CF $^+$ + tree-based ERC) method effectively computes clusters over large data sets. Furthermore, it does not require a predefined number of clusters to compute the clusters. We present in-depth theoretical and experimental analyses of our method. Experimental results on very large synthetic data sets demonstrate that the proposed approach is effective in terms of cluster quality and robustness and is significantly faster than existing clustering methods. In addition, we apply our clustering method to real data sets and achieve promising results.
Decreasing Airflow Velocity in Hard Disk Drives With a Spoiler and Bypass

Airflow changes in a hard disk drive (HDD) with a bypass and a spoiler were clarified by large eddy simulation (LES) and particle image velocimetry (PIV). These analyses show that the spoiler decreases the flow velocity near the arm by decreasing average flow velocity between the disks such as diverging the flow into the bypass channel, and by moving the high-speed-flow area toward the inner-radius area of the disks. The arm vibration is reduced with 30% by these effects
Physical Characterization of Eri Silk Fibers Produced in Kenya

ABSTRACT Eri silk produced in Kenya was characterized for sericin content, moisture content, surface morphology, thermal properties, functional groups, crystallinity, and single fiber tensile strength. It was found that Kenyan Eri silk possesses comparable physical properties to those of commercial silk producing countries. At a degummed tensile strength of 6.81cN, Kenyan Eri silk had comparable strength despite having low crystallinity (29.2%). This is an indication that on optimizing rearing procedures and practices of Eri silkworms to certain regions of Kenyan environment, better quality silk fibers can be produced that are competitive in the world market.
Supporting mathematics vocabulary instruction through mathematics curricula

Abstract This study examines four of the most commonly-used core mathematics curricula in the USA for evidence of support for research-based instructional strategies for mathematics vocabulary in first and second grade. Content analyses of the teachers’ editions of two units for each grade level were analyzed per curriculum (n = 16). Statistically significant differences among curricula were found for number of target words (range 6–51 per unit), level of difficulty of terms (basic to technical), and number of support strategies per word. Multiple means of representation varied in terms of verbal and non-verbal strategies for target terms. These differences indicate children are experiencing substantially different mathematics vocabulary learning opportunities, which may impact later mathematics achievement. Implications for practice, curriculum development, and future research are addressed.
Whistler Waves Driven by Field‐Aligned Streaming Electrons in the Near‐Earth Magnetotail Reconnection

We analyze Magnetospheric Multiscale Mission observations of whistler waves and associated electron field‐aligned crescent distribution in the vicinity of the magnetotail near‐Earth X‐line. The whistler waves propagate outward from the X‐line in the neutral sheet. The associated field‐aligned streaming electrons exhibit a crescent‐like shape, with an inverse slope (df/d|v|||>0) at 1–5 keV. The parallel phase velocity of the waves is in the range (1–5 keV) of the inverse slope of the field‐aligned crescents in the velocity space. We demonstrate that the observed whistler waves are driven by the electron field‐aligned crescents through Landau resonance. The cyclotron resonance is at the high‐energy tail with negligible free energy of pitch angle anisotropy in these events.
New product development-processes in the fashion industry

Purpose The purpose of this paper is, first, to examine the design requirements of Islamic fashion in the new product-development process; second, to explore the different practices of new product-development activities from successful and unsuccessful new product lines; and third, to investigate the sequence of the new product-development practice in the fashion industry, specifically the Islamic fashion industry in Indonesia. Design/methodology/approach Questionnaires were distributed and semi-structured interviews were conducted to collect information regarding the practice of the new product-development activities. The Mann–Whitney U test was performed based on the quality of the new product-development activities of 100 Islamic fashion firms, including five innovative companies that had won several awards in Indonesia. An analysis of the extent to which fashion firms were engaging in new product-development activities provided a more detailed picture of the sequence of those activities. Findings Islamic norms were adapted during the early design and promotional phases of new product development in Islamic fashion. Various choices of design and colour in Islamic fashion were also perceived as a way of preaching to women to dress more accordingly to the Islamic norm. The new product-development activities that were conducted differently for successful vs unsuccessful new product lines were idea conceptualisation, market analysis, technical and engineering analysis, financial analysis and commercialisation. The commercialisation phase was given the least priority of all the activities. Nevertheless, it contributed to the very first communication to the customers about new product lines. Originality/value This study makes an important contribution to the deeper and more detailed research on how Islamic fashion companies perceive Islamic values during new product developments and how they perform new product-development activities between successful and unsuccessful products.
Neuron-specific knockouts indicate the importance of network communication to Drosophila rhythmicity

Animal circadian rhythms persist in constant darkness and are driven by intracellular transcription-translation feedback loops. Although these cellular oscillators communicate, isolated mammalian cellular clocks continue to tick away in darkness without intercellular communication. To investigate these issues in Drosophila, we assayed behavior as well as molecular rhythms within individual brain clock neurons while blocking communication within the ca. 150 neuron clock network. We also generated CRISPR-mediated neuron-specific circadian clock knockouts. The results point to two key clock neuron groups: loss of the clock within both regions but neither one alone has a strong behavioral phenotype in darkness; communication between these regions also contributes to circadian period determination. Under these dark conditions, the clock within one region persists without network communication. The clock within the famous PDF-expressing s-LNv neurons however was strongly dependent on network communication, likely because clock gene expression within these vulnerable sLNvs depends on neuronal firing or light.