Miracle-dz/UniFAR-FTUs huggingface dataset:
Situation Model and Embodiment

There are decades of evidence based on the fundamental language logic, showing that people create situation models when they understand text, which will be presented in more detail in the second part of this paper. However, after half a century of discussion among psychologists, it remains unclear whether these situation models are implemented in modality-specific simulations. To be able to sort out more clearly the clues whether the situation models are embodied or disembodied, in this work, we briefly review behavioural evidence for situated text understanding, and then evaluate the available evidence that bears on the question of whether situation models are “embodied” or “disembodied”. We try to suggest further ways, such as using PET and fMRI technology, in which this question might be investigated effectively in the end of this paper.
Valid-NEO: A Multi-Omics Platform for Neoantigen Detection and Quantification from Limited Clinical Samples

Simple Summary Neoantigens have emerged as highly personalized cancer therapeutic targets in recent years. Numerous studies have reported phenomenal therapeutic efficacy through treatments targeting cancer patient-specific neoantigens. Despite the growing interests, to identify druggable neoantigens is still largely dependent on genomic sequencing and AI algorithm-based prediction, which have been proven to be error-prone. Numerous reported mass spectrometry-based neoantigen assays utilized multi-gram levels of the tumor tissues, required invasive procedures, and were not practically feasible for most cancer patients, particularly patients that were non-operable or with early diseases, who may benefit most from immunotherapeutic approaches. Here we reported an integrated pipeline that can detect and quantify patient-specific neoantigens from a very limited amount of patient samples through a variety of innovative designs and optimizations. It may enable neoantigen-based therapeutics to benefit a broader spectrum of cancer and non-cancer patients. Abstract The presentation of neoantigens on the cell membrane is the foundation for most cancer immunotherapies. Due to their extremely low abundance, analyzing neoantigens in clinical samples is technically difficult, hindering the development of neoantigen-based therapeutics for more general use in the treatment of diverse cancers worldwide. Here, we describe an integrated system, “Valid-NEO”, which reveals patient-specific cancer neoantigen therapeutic targets from minute amounts of clinical samples through direct observation, without computer-based prediction, in a sensitive, rapid, and reproducible manner. The overall four-hour procedure involves mass spectrometry analysis of neoantigens purified from tumor samples through recovery of HLA molecules with HLA antibodies. Valid-NEO could be applicable to the identification and quantification of presented neoantigens in cancer patients, particularly when only limited amounts of sample are available.
Piloted Simulation of the Rotorcraft Wind Turbine Wake Interaction during Hover and Transit Flights

Helicopters are used for offshore wind farms for maintenance and support flights. The number of helicopter operations is increasing with the expansion of offshore wind energy, which stresses the point that the current German regulations have not yet been validated through scientific analysis. A collaborative research project between DLR, the Technical University of Munich, the University of Stuttgart and the University of Tübingen has been conducted to examine the sizes of the flight corridors on offshore wind farms and the lateral safety clearance for helicopter hoist operations at offshore wind turbines. This paper details the results of piloted helicopter simulations in a realistic offshore wind farm scenario. The far-wake of rotating wind turbines and the near-wake of non-rotating wind turbines have been simulated with high-fidelity computational fluid dynamics under realistic turbulent inflow conditions. The resulting flow fields have been processed by superposition during piloted simulations in the research flight simulator AVES to examine the flight corridors in transit flights and the lateral safety clearance in hovering flights. The results suggest a sufficient size for the flight corridor and sufficient lateral safety clearance at the offshore wind turbines in the considered scenarios.
Empowering Local Communities to Preserve their Folklore: A Project in Eastern Sumba

This article p resents a project of empowering local communit ies in eastern Sumba to preserve their folklo re. Culture encounters in globalized world encourage local communit ies to reflect on the dynamics and vitality o f their own culture. Given the fact that oral-based communit ies are marginalized in articu lating their cultural identity, this project aimed to involve local communities in eastern Sumba to preserve their folkloric expressions. Activities comprised focus group discussions, folklore research, and d igital documentation of folk music and dance. Th is project is expected to establish collaboration between scholars and local communit ies to promote the importance of local knowledge preservation and the needs for the digital documentation to support future data preservation.
Primordial Germ Cell Development in the Poeciliid, Gambusia holbrooki, Reveals Shared Features Between Lecithotrophs and Matrotrophs

Metazoans exhibit two modes of primordial germ cell (PGC) specification that are interspersed across taxa. However, the evolutionary link between the two modes and the reproductive strategies of lecithotrophy and matrotrophy is poorly understood. As a first step to understand this, the spatio-temporal expression of teleostean germ plasm markers was investigated in Gambusia holbrooki, a poecilid with shared lecitho- and matrotrophy. A group of germ plasm components was detected in the ovum suggesting maternal inheritance mode of PGC specification. However, the strictly zygotic activation of dnd-β and nanos1 occurred relatively early, reminiscent of models with induction mode (e.g., mice). The PGC clustering, migration and colonisation patterns of G. holbrooki resembled those of zebrafish, medaka and mice at blastula, gastrula and somitogenesis, respectively—recapitulating features of advancing evolutionary nodes with progressive developmental stages. Moreover, the expression domains of PGC markers in G. holbrooki were either specific to teleost (vasa expression in developing PGCs), murine models (dnd spliced variants) or shared between the two taxa (germline and somatic expression of piwi and nanos1). Collectively, the results suggest that the reproductive developmental adaptations may reflect a transition from lecithotrophy to matrotrophy.
Project 8: R&D for a next-generation neutrino mass experiment

Project 8 is a next-generation direct neutrino mass experiment measuring the spectral endpoint region of tritium beta decays. The energy of the beta decay electrons is measured using Cyclotron Radiation Emission Spectroscopy (CRES) which has been demonstrated by the Project 8 collaboration with both krypton and molecular tritium confined in a section of a microwave guide. To reach the target sensitivity of 40 meV/22, major technological research and development is necessary. Building on the milestones achieved so far, I will present the next phases of Project 8: In Phase III, atomic tritium will be produced and trapped magnetically, and cyclotron radiation emission spectroscopy will be demonstrated in free space which allows larger detection volumes. The knowledge gained from Phase III will enable the design and operation of a large-volume atomic tritium experiment, sensitive to the entire mass range allowed by the inverse neutrino mass ordering.
Modeling and Prediction of Civil Aeronautic Passenger Capacity by Using ARIMA Models

A general expression of ARIMA models is given, and the procedures to model and predict passenger capacity using ARIMA models are provided. Feasibility-study experiments show that ARIMA models can be used to model and predict actual passenger capacity. The result of an 8-step short-term forecast is obtained and its maximum relative error is 0.08.
The effect of toxic leadership on turnover intention and counterproductive work behaviour in Indonesia public organisations

PurposeLeadership has been known for its tremendous impact on employees' outcomes in any organisation. Constructive leadership positively impacts employees, while destructive leadership causes counterproductive work behaviours (CWB). This study aims to investigate the effect of toxic leadership on employees' CWB via the role of turnover intention by employing the psychological contract theory.Design/methodology/approachThe participants were recruited using various recruitment methods such as online recruitment and alumni networks. After dropping some participants who failed to complete the three-wave data collection procedure, 457 responses were used for the final data analysis. The participants came from various public organisations in Indonesia (e.g. hospitals). FindingsThe results found that the effect of toxic leadership on employees' CWB was mediated by the role of turnover intention. Under a toxic leader, employees might intend to leave the organisations and commit CWB as the employees perceived the psychological contract breach.Practical implicationsFirstly, public organisations should implement some strategies to reduce the emergence of toxic behaviours. Secondly, public organisations should evaluate and examine how leadership is exercised within public organisations. Lastly, the organisations must ensure that their leaders do not breach employees' psychological contracts.Originality/valueThis study has highlighted the effect of toxic leadership on CWB in public service organisations by employing a psychological contract theory and a power distance perspective.
Extension and application of cognitive work analysis to improve pedestrian safety at rail level crossings

Pedestrian safety at rail level crossings (RLXs) is a concern for government, the transport industry and the community. Collisions between trains and pedestrians are traditionally viewed as the result of errors or violations committed by pedestrians. However, as RLXs are complex sociotechnical systems, collisions are better understood as emergent properties of interactions amongst and between human and technical components within the system. Cognitive work analysis (CWA) is a powerful analytical framework that offers a sophisticated understanding of the functioning of RLXs as relevant to pedestrian safety, through identifying the constraints on pedestrian behaviour in this context. It does not, however, provide its users with guidance about how the findings of the analysis can be used to improve sociotechnical system functioning. Accordingly, the aim of this research was the development and evaluation of a CWA-based approach to support the design of complex sociotechnical systems, and the application of this approach to provide recommendations for RLX design to improve pedestrian safety. A secondary aim of the research was to investigate pedestrian behaviour within the RLX system using CWA. Drawing on systems theory, and more specifically, sociotechnical systems theory, the outcome of this research is a CWA design toolkit (the CWA-DT). The development and refinement of the CWA-DT is illustrated through a proof of concept application in the domain of public transport ticketing. Positive evaluation results were obtained and necessary refinements to the toolkit were implemented in the second version. A full evaluation of the toolkit was then undertaken within the complex, safety critical domain of RLXs. This evaluation found that while the CWA-DT could be considered a useful method, its application did not lead to the creation of design concepts that fully aligned with sociotechnical systems theory. The application did, however, lead to designs that were rated by human factors experts as more effective than the existing system design. These findings suggest that the sociotechnical systems theory approach may not provide an appropriate design philosophy in a public safety context. However, merging ideas and concepts from sociotechnical systems theory with existing paradigms such as safety management can lead to innovation and has the potential to improve safety performance. Awards: Winner of the Mollie Holman Doctoral Medal for Excellence, Monash Injury Research Institute, 2015.
Media Effects on High School and University Students’ Views on Popular Clothes

The theme of our research is the influence of popular logo on the behaviour of high school and college students. More and more high school and college students are attracted by popular brands, and it seems that popular logo becomes a fashion trend within those student communities. For this phenomenon, we consider that media plays an important role in this kind of consumer behaviour. In contemporary society, because of the rapid development of media, its influence needs to be taken seriously, especially on young people, which contributes to understand and change the consumer psychology of those people. In order to obtain relevant data for our research, we use a questionnaire with 15 individual questions. The answers to the questionnaire are used to analyse the correlation between the research question we proposed and the respondents’ perspectives. Overall, we investigate respondents’ opinions from three aspects, consumption idea, influence factor, and views on actions. In conclusion, the answers to the questionnaire and our analysis suggest that popular logos have an irreplaceable and unique domain in the clothing market nowadays. Meanwhile, social media greatly promote the popularity of those brands. It can be seen from the influence of external packing, spokesperson and indirect advertisement on these students’ choices of popular brands. Besides, most young people pursuit those clothes mainly because popular logos fit their preferences and they are generally rational for the consume on popular logos. In the era of media, it is significant to realize the media effect and shape the correct consumption values of high school and college students on these popular brands.
Analysis of Exposure to Seabed of Legs During Positioning of Jack-up

The motion responses of Jack-up during positioning and lowing were investigated. The Jack-up's motion excited by wave is studied during floating condition as lowing legs. This paper took a Jack-up as example,the panel model and Morison model are set up by SESAM software,the wave loads and RAOs of responses in frequency domain were calculated based on the 3D potential flow theory and Morison equation.Furthermore,short term statistic of the Jack-up's motion was predicted,the lowing height of exposure to seabed of legs and the corresponding parameters of the marine environment are determined.
Persistence of the Strictly Endemic Plants of Forest Margins: The Case of Cirsium alpis-lunae in the Northern Apennines (Italy)

Narrow endemic plants constitute a pivotal group for conservation, being often reduced to a small contingent of individuals and frequently threatened. However, effective conservation actions require reliable basic information about distribution range, ecological requirements, and population traits. Nevertheless, such knowledge results are incomplete or even completely missing for some neglected or recently described plants, such as Cirsium alpis-lunae, a thistle exclusive to the N-Apennines (Italy). To fill this gap, all sites where C. alpis-lunae grow were monitored, and data on the site and population traits were collected. Our results indicated that this plant is restricted to 16 scattered sites, varied in surface area and number of individuals. Reproductive and juvenile plants showed to be affected by roughly the same variables, in particular the surface of the site, the slope aspect, and the canopy cover. The narrow ecological niche of C. alpis-lunae was mainly determined by the canopy cover, and where coverage increases, the number of individuals decreases. The individuals only grow at forest edges, where the peculiar ecological conditions are limiting factors for the development of forestry cover; some other factors (i.e., high inclination and instability of the substrate) contribute to limiting the development of forestry vegetation and guarantee the persistence of these ecotones. Despite the great difficulties in accessing the sites where this species grows, this study presents, for the first time, a complete picture of the C. alpis-lunae population and yielded important data to identify effective conservation measures.
The Role of Peritoneal Dialysis in Different Phases of Kidney Transplantation

The utilization of peritoneal dialysis (PD) has been increasing in the past decade owing to various government initiatives and recognition of benefits such as better preservation of residual renal function, quality of life, and lower cost. The Advancing American Kidney Health initiative aims to increase the utilization of home therapies such as PD and kidney transplantation to treat end stage kidney disease (ESKD). A natural consequence of this development is that more patients will receive PD, and many will eventually undergo kidney transplantation. Therefore, it is important to understand the effect of pretransplant PD on posttransplant outcomes such as delayed graft function (DGF), rejection, thrombosis, graft, and patient survival. Furthermore, some of these patients may develop DGF, which raises the question of the utility of PD during DGF and its risks. Although transplant is the best renal replacement therapy option, it is not everlasting, and many transplant recipients must go on dialysis after allograft failure. Can PD be a good option for these patients? This is another critical question. Furthermore, a significant proportion of nonrenal solid organ transplant recipients develop ESKD. Is PD feasible in this group? In this review, we try to address all of these questions in the light of available evidence.
Differential Effects of Fundamental and Longitudinal Life History Trade-Offs on Delay Discounting: An Evolutionary Framework

We synthesized life history theory and the antagonistic pleiotropy hypothesis to form an integrative framework for understanding delay discounting (DD). We distinguished between fundamental and longitudinal life history trade-offs to explain individual and age differences of DD. Fundamental life history trade-offs are characterized by life history strategies (LHS), describing how individuals adjust reproductive timing according to childhood environments, while longitudinal life history trade-offs characterize how individuals make trade-offs between early- vs. late-life reproduction as a function of age. Results of a life-span sample (242 Chinese participants) supported several theoretical predictions: (a) slower LHS predicted lower DD; (b) the relationship between chronological age and DD was U-shaped; (c) the effects of age and LHS were differential. Mechanisms underlying fundamental and longitudinal trade-offs were explored. Regarding fundamental trade-offs, LHS mediated the effects of childhood environment on DD. Regarding longitudinal trade-offs, the U-shaped relationship was more evident between physical age and DD: older adults who were in poorer physical health felt older and exhibited a higher DD. Neither the time perspective nor anticipatory time perception mediated the effect of life history trade-offs. We concluded that DD was a product of two distinct life history trade-offs, reflecting both the trait-like quality and age-related development.
Violence, runaway, and suicide attempts among people living with schizophrenia in China: Prevalence and correlates

Background People living with schizophrenia are at higher risk of disruptive behaviors, including violence, running away from home, and suicide attempts, which often co-occur and are highly correlated, yet seldom studied together. The current study investigated the frequency and correlates of disruptive behaviors among a Chinese community sample of individuals living with schizophrenia. Methods A cross-sectional study was conducted among 400 individuals living with schizophrenia from 12 communities. Data about disruptive behaviors in the past 2 months was collected using self-designed questionnaires. Clinical characteristics including psychiatric symptoms, depression, anxiety, disability, and functioning were collected by internationally standardized assessment instruments. Results About one-fifth (21%) of the subjects had experienced at least one form of disruptive behavior in the past 2 months. Violence was the most commonly reported (17.25%), which included damaging property (15%) and physical violence toward others (7.5%); followed by running away (6.5%), and suicide attempts (4%). Logistic regression analysis suggested that medication non-adherence (OR = 4.96, 95% CI [1.79–13.72]), involuntary hospital admission (OR = 5.35, 95% CI [2.06–13.87]), depression (OR = 2.34, 95% CI [1.07–5.10]), and lower social functioning (OR = 0.97, 95% CI [0.93–0.99]) were independently associated with a higher risk of disruptive behaviors. Conclusions The overlap among three forms of disruptive behaviors warrants them to be assessed and studied together in clinical, research, and policy fields. The significant association between disruptive behaviors with medication non-adherence, involuntary admission, depression, and lower social functioning indicates the need for integrated, targeted, and needs-based intervention programs to be developed for the prevention and treatment of these disruptive behaviors.
Fatalness assessment of flight safety hidden danger based on support vector machine

A method for fatalness assessment of flight safety hidden danger,based on support vector machine(SVM),was proposed.And the corresponding model,which took the basic assessment factors of flight safety hidden danger fatalness as input node and assessment results as output node,was built.Then the safety situation of a regiment of China Air Force was assessed.The results showed that,for fatalness assessment of flight safety hidden danger,SVM has better performance on precision,rapidity and realization in comparison with the traditional neural network.
Let the Past Rest: The Influence of Effortful Control on Directed Forgetting of Explicit and Implicit Memories

The ability of directed forgetting is closely related to the individuals’ level of effortful control. This study aims to investigate the effect effortful control has on the level of directed forgetting. Forty-nine Chinese participants of ages between 18 and 25 were invited to this study. Participants were selected according to their level of effortful control, and they were divided into four groups, with each group doing different memory tests. Afterward, they were presented with Chinese characters that are less common, followed by an interference task. In the next stage, participants were tested with a recognition task or perceptual identification task. In explicit memory, there was an interaction effect between cues and participants’ performances in memory tasks (p < 0.05), while in implicit memory, no such effect was observed (p > 0.05). The findings suggest that although directed forgetting exists in both explicit and implicit memory, the level of effortful control does not affect implicit memory, and in explicit memory, individuals with a higher level of effortful control show the better ability of directed forgetting This study provides evidence that there is a relationship between temperament and memory.