Miracle-dz/UniFAR-FTUs huggingface dataset:
ARComposer: Authoring Augmented Reality Experiences through Text

Augmented Reality (AR) is rapidly gaining popularity, enhancing human perception of the real world by augmenting digital experiences. Existing tools for authoring AR scenes are either template based or require domain knowledge from experts, and are therefore restrictive. ARComposer is a novel interface that enables easy authoring of AR experiences from free-form text describing the scene. Our proposed interface allows creators to compose varied scenes comprising of multiple objects with diverse relationships to each other as well as human models with animations, starting merely with a textual description. A qualitative evaluation shows that ARComposer provides a good flow experience to its users. Furthermore, a crowd-sourced experiment evaluating various aspects of the rendered AR scenes indicates the viability of the proposed approach.
Soft Inkjet Circuits: Rapid Multi-Material Fabrication of Soft Circuits using a Commodity Inkjet Printer

Despite the increasing popularity of soft interactive devices, their fabrication remains complex and time consuming. We contribute a process for rapid do-it-yourself fabrication of soft circuits using a conventional desktop inkjet printer. It supports inkjet printing of circuits that are stretchable, ultrathin, high resolution, and integrated with a wide variety of materials used for prototyping. We introduce multi-ink functional printing on a desktop printer for realizing multi-material devices, including conductive and isolating inks. We further present DIY techniques to enhance compatibility between inks and substrates and the circuits' elasticity. This enables circuits on a wide set of materials including temporary tattoo paper, textiles, and thermoplastic. Four application cases demonstrate versatile uses for realizing stretchable devices, e-textiles, body-based and re-shapeable interfaces.
Pre-screen: Assisting Material Screening in Early-stage of Video Editing

Video editing is a difficult task for both professionals and amateur editors. One of the biggest reasons is that screening useful clips from raw material in the early stage of editing is too much time-consuming and laborious. To better understand current difficulties faced by users in editing task, we first conduct a pilot study involving a survey and an interview among 20 participants. Based on the results, we then design Pre-screen, a novel tool to provide users with both global-view and detailed-view video analysis as well as material screening features based on intelligent video processing, analysis and visualization methods. User study shows that Pre-screen can not only effectively help users screen and arrange raw video material to save much more time than a widely used video editing tool in video editing tasks, but also inspire and satisfy users.
Skin-On Interfaces: A Bio-Driven Approach for Artificial Skin Design to Cover Interactive Devices

We propose a paradigm called Skin-On interfaces, in which interactive devices have their own (artificial) skin, thus enabling new forms of input gestures for end-users (e.g. twist, scratch). Our work explores the design space of Skin-On interfaces by following a bio-driven approach: (1) From a sensory point of view, we study how to reproduce the look and feel of the human skin through three user studies;(2) From a gestural point of view, we explore how gestures naturally performed on skin can be transposed to Skin-On interfaces; (3) From a technical point of view, we explore and discuss different ways of fabricating interfaces that mimic human skin sensitivity and can recognize the gestures observed in the previous study; (4) We assemble the insights of our three exploratory facets to implement a series of Skin-On interfaces and we also contribute by providing a toolkit that enables easy reproduction and fabrication.
The Stockholm Spinal Cord Uro Study: 1. Basic characteristics and problem inventory

Abstract Objective: To assess urinary tract function and complications in a regional prevalence group of patients with traumatic spinal cord injury (SCI), and to estimate risk factors for recurring complications. Materials and methods: A total of 412 patients who attended a yearly check-up at the Spinalis SCI clinic were included. A regional follow-up programme for neurogenic bladder dysfunction was applied, including S-creatinine and S-cystatin-C, urine culture, residual urine, ultrasound of kidneys, urodynamic studies, and a questionnaire regarding complications during the preceding year. Descriptive statistics and logistic regression were used to estimate risk factors. Results: All patients completed blood tests and the questionnaire. A urine culture was completed by 96%, ultrasound by 88%, residual urine by 75%, urodynamics by 51%, and all parts of the study by 47%. One quarter of patients displayed pathological findings regarding kidney function. Urodynamics verified neurogenic overactive bladder in a majority, and a high proportion with intravesical filling pressures above 40 cm H2O, a commonly used cut-off level for kidney safety. Subjectively, 47% of patients reported complications during the past year with urinary tract infection (UTI) as the most common one. Other complications were rare. Conclusions: With the aid of a regular follow-up programme, SCI patients can achieve a relatively stable situation regarding urinary tract function. UTI is the most common complication. Indicators of renal complications are frequent but not clearly related to the number of UTIs, nor to intravesical filling pressures. Main risk factors for complications are cervical levels and more complete neurological lesions.
Observing postprandial bowel movements in diaper-dependent toddlers

The gastrocolic reflex is a response of the colon to the presence of food in the stomach. Our goal was to observe bowel movements in healthy infants and toddlers not yet toilet trained, in response to a meal. Stool behavior of 40 toddlers, aged 18–27 months, was monitored. We observed a bowel movement within the first hour after a meal in 75% of the children. This occurred 15, 30 or 60 minutes after a meal in, respectively, 25%, 48% and 66% of the observations. If we limit to the ones that actually defecated, 37% would defecate within 15 minutes and 72% within half an hour. Fifty-nine percent of all children defecated in the morning, 54% at noon and 28% in the evening. In conclusion, we believe the gastrocolic reflex can be used as a facilitating factor to help a child to defecate on the potty, 15–30 minutes after a meal. In 50% of the cases, a child will have a bowel movement on the potty and learn to defecate on it much easier.
A comparison of trends in wastewater-based data and traditional epidemiological indicators of stimulant consumption in three locations.

AIMS To compare long-term trends in wastewater data with other indicators of stimulant use in three locations and to test the reliability of estimates based on one week of sampling. DESIGN Comparison of trends in quantities ('loads') of stimulants or their metabolites in wastewater with trends in other indicators of stimulant use (e.g. treatment, police, population survey data). SETTING AND PARTICIPANTS Populations in Oslo (Norway), South-East Queensland (Australia) and Eindhoven (The Netherlands). MEASUREMENTS Wastewater data were modelled for MDMA (3,4-Methyl​enedioxy​methamphetamine), benzoylecgonine (a metabolite of cocaine), amphetamine and methamphetamine in Oslo; benzoylecgonine in Eindhoven; and methamphetamine in South-East Queensland. Choice of stimulants modelled in each region was primarily determined by availability of useable data. FINDINGS In Oslo, wastewater data, driving under the influence of drugs statistics and seizure data all suggested increasing MDMA use between 2009 and 2017. In South-East Queensland, there was an estimated 31.1% (95%CI 29.4-32.9%) annual increase in daily loads of methamphetamine in wastewater between 2009 and 2016, compared with a 14.1% (95%CI 10.9-17.3%) annual increase in seizures. Some of the increase in wastewater can be explained by increased purity. In Eindhoven, there was no evidence of a change in cocaine consumption from wastewater, but a reduction was observed in numbers in treatment for cocaine use from 2012 to 2017. In approximately half the cases examined in Oslo, credible intervals around estimates of annual average loads from a regression model versus estimates based on a single week of sampling did not overlap. CONCLUSIONS Long-term trends in loads of stimulants in wastewater appear to be broadly consistent with trends in other indicators of stimulant use in three locations. Wastewater data should be interpreted alongside epidemiological indicators and purity data. One week of wastewater sampling may not be sufficient for valid inference about drug consumption.
Utilization of banana crop residue as an agricultural bioresource for the production of acetone‐butanol‐ethanol by Clostridium beijerinckii YVU1

This study aimed to produce acetone‐butanol‐ethanol (ABE) using lignocellulosic crop residues as renewable bioresources. Butanol production from banana crop residue (BCR) was studied using a newly isolated solventogenic Clostridium beijerinckii YVU1. BCR is one of the abundant lignocellulosic substrates available in tropical countries containing 4·3 ± 3·5% cellulose, 28·5 ± 3·0% hemicellulose and 20·3 ± 2·6% lignin. The sequential dilute alkali and acid pretreatments solubilized 69% of lignin and 73% of hemicellulose. Ten percent (w/v) of pretreated substrate was subjected to enzymatic saccharification with cellulase, and it was found to release 0·481 ± 0·035 g glucose per g pretreated biomass. In the batch fermentation process, 20·5 g l−1 ABE (14·0 g l−1 of butanol, 5·4 g l−1 of acetone and 1·1 g l−1 of ethanol) was obtained. The executed fermentation process yielded 0·39 g ABE per g hydrolysate with 0·14 g l−1 h−1 of volumetric productivity. On the basis of the results, we believe that sequential alkali and acid pretreatment on the enzymatic hydrolysis for butanol production is indeed a technology with the potential to be applied and newly isolated. C. beijerinckii YVU1 is also a potential candidate organism for butanol production agricultural residues.
Do They Really Mean It? Children’s Inference of Speaker Intentions and the Role of Age and Gender

Interpreting other people’s intentions during communication represents a remarkable challenge for children. Although many studies have examined children’s understanding of, for example, sarcasm, less is known about their interpretation. Using realistic audiovisual scenes, we invited 124 children between 8 and 12 years old to watch video clips of young adults using different speaker intentions. After watching each video clip, children answered questions about the characters and their beliefs, and the perceived friendliness of the speaker. Children’s responses reveal age and gender differences in the ability to interpret speaker belief and social intentions, especially for scenarios conveying teasing and prosocial lies. We found that the ability to infer speaker belief of prosocial lies and to interpret social intentions increases with age. Our results suggest that children at the age of 8 years already show adult-like abilities to understand literal statements, whereas the ability to infer specific social intentions, such as teasing and prosocial lies, is still developing between the age of 8 and 12 years. Moreover, girls performed better in classifying prosocial lies and sarcasm as insincere than boys. The outcomes expand our understanding of how children observe speaker intentions and suggest further research into the development of teasing and prosocial lie interpretation.
IL‐35, a double‐edged sword in cancer

Interleukin 35 (IL‐35), a cytokine mainly produced by regulatory T cells (Treg cells), is composed of an Epstein‐Barr virus–induced gene 3 β‐chain and an IL‐12 p35 α‐chain. IL‐35 causes tumorigenicity in cancer, protects cancer cells against apoptosis, and facilitates cancer progression. However, a few reports have referred to its contradictory roles in cancer prevention. Therefore, the exact purpose of this cytokine in cancer development has become a fundamental question that needs to be answered. In this review, we explain the structure of IL‐35 and its receptors and their different signaling pathways. Finally, the function of IL‐35 in some cancers and the possible application of this cytokine in approaches for cancer therapy have been discussed.
Removal ability of different underlying surfaces to near-surface particulate matter

ABSTRACT Atmospheric particulate matter is a wide-ranging environmental pollutant that can cause serious harm and poses a serious threat to public health. In this study, the near-surface particulate matter removal ability was quantitatively analyzed and compared for different land types under different pollution levels. The results showed that the concentrations of particulate matter 10 μm or less in diameter (PM10) and 2.5 μm or less in diameter (PM2.5) were higher in the morning and lower in the afternoon and that the seasonal variation was autumn > winter > spring > summer at a forest site. The diurnal concentration of particulate matter at a wetland site decreased continuously, with a seasonal variation of winter > autumn > spring > summer. The annual variation in the particulate matter concentration was higher in 2017 than in 2016 at both the forest and wetland sites. Forests remove particulate matter via plant leaves and root absorption, and wetlands rely on the enhancement of the relative air humidity to promote the absorption and accumulation of particles. For different air pollution levels, the deposition flux of PM2.5 increased with the pollution gradient. For the same air quality pollution level, the deposition flux of PM2.5 at the forest site was approximately 1.29 times higher than that at the wetland site. Data concerning PM10 in forests and wetlands are lacking. The results show that the deposition effect of the forest on particulate matter was better than that of the wetland. GRAPHICAL ABSTRACT
Oral Rehabilitation of Patients Sustaining Orofacial Injuries: The UPenn Initiative

Tissue injuries in the oral and maxillofacial structures secondary to trauma, warfare, ablative cancer, and benign tumor surgery result in significant losses of speech, masticatory and swallowing functions, aesthetic deformities, and overall psychological stressors and compromise. Optimal oral rehabilitation remains a formidable challenge and an unmet clinical need due to the influence of multiple factors related to the physiologic limitations of tissue repair, the lack of site and function-specific donor tissues and constructs, and an integrated team of multidisciplinary professionals. The advancements in stem cell biology, biomaterial science, and tissue engineering technologies, particularly the 3-dimensional bioprinting technology, together with digital imaging and computer-aided design and manufacturing technologies, have paved the path for personalized/precision regenerative medicine. At the University of Pennsylvania, we have launched the initiative to integrate multidisciplinary health professionals and translational/clinical scientists in medicine, dentistry, stem cell biology, tissue engineering, and regenerative medicine to develop a comprehensive, patient-centered approach for precision and personalized reconstruction, as well as oral rehabilitation of patients sustaining orofacial tissue injuries and defects, especially oral cancer patients.
Preparation of Liquid Oral Mucoadhesive Gastro-retentive System of Nimodipine.

BACKGROUND Nimodipine is calcium channel blocker frequently used in critical care settings. It is mainly absorbed from upper gastrointestinal tract. Accordingly, development of gastroretentive formulation will be beneficial. The benefit would be maximized for critical care patients if the developed system was in liquid form to facilitate administration through nasogastric tubing. OBJECTIVE Development of gastro-retentive liquid oral controlled release formulation of nimodipine via in situ gellation. Methods: Nimodipine dissolution was improved by solid dispersion (SD) using poloxamer 407. Sodium alginate solutions (1, 1.5 and 2%w/v) were loaded with the optimized SD microparticles. Carboxymethylcellulose was added to modulate the release and to augment mucoadhesion power. All in situ gelling alginate solutions were characterized regarding viscosity, gelling capacity and drug release. SD microparticles showed considerable improvement in nimodipine dissolution. Results: All alginate systems were pourable. Increasing alginate concentration increased the gelling capacity and reduced drug release rate. Addition of carboxymethylcellulose produced greater control over drug release rate. X-ray radiography showed successful stomach-retention over 8 hours in rabbits, which correlates with the controlled release pattern of the developed systems. Conclusion: The study provides the formulator with a range of gastroretentive controlled release formulations of nimodipine while maintaining the convenience of administration via nasogastric tubing with potential for enhanced bioavailability.
Evolutionary and cardio‐respiratory physiology of air‐breathing and amphibious fishes

Air‐breathing and amphibious fishes are essential study organisms to shed insight into the required physiological shifts that supported the full transition from aquatic water‐breathing fishes to terrestrial air‐breathing tetrapods. While the origin of air‐breathing in the evolutionary history of the tetrapods has received considerable focus, much less is known about the evolutionary physiology of air‐breathing among fishes. This review summarizes recent advances within the field with specific emphasis on the cardiorespiratory regulation associated with air‐breathing and terrestrial excursions, and how respiratory physiology of these living transitional forms are affected by development and personality. Finally, we provide a detailed and re‐evaluated model of the evolution of air‐breathing among fishes that serves as a framework for addressing new questions on the cardiorespiratory changes associated with it. This review highlights the importance of combining detailed studies on piscine air‐breathing model species with comparative multi‐species studies, to add an additional dimension to our understanding of the evolutionary physiology of air‐breathing in vertebrates.
First trimester ultrasound features of X-linked Opitz syndrome and early molecular diagnosis: case report and review of the literature

Abstract X-linked Opitz G/BBB syndrome (XLOS) is a multiple congenital disorder inherited in an X-linked manner. XLOS may be suspected, in prenatal age, on the basis of sonographic findings in the second and/or third trimester of gestation. Pathogenetic variants in MID1 gene have been reported in individuals with XLOS. Prenatal genetic testing is offered for pregnancies at risk, in which the mutation in the family has been identified. To date no cases of prenatal diagnosis, based on first-trimester ultrasound data, have been reported. We present a case of a fetus at 12 gestational weeks with ultrasound multiple anomalies, including increased nuchal translucency, heart defects, cleft lip and palate, enlarged fourth ventricle absence of ductus venosus and family hystory of XLOS. The genetic prenatal test detected the c(0). 1286-1G > T mutation of MID1 gene. Data about prenatal ultrasonographic findings consistent with XLOS are limited to second and third trimester. This is the first case reporting ultrasound detectable midline defects suggestive of XLOS as early as the first trimester of gestation. This case also suggests that when multiple anomalies are detected in a fetus with normal chromosomal structure, the possibility of a monogenic disorder must be considered.
The interfacial tension of the water-diluted bitumen interface at high bitumen concentrations measured using a microfluidic technique.

The interfacial tension (IFT) is a critical parameter to inform our understanding of the phenomena of drop breakup and droplet-droplet coalescence in sheared water-in-diluted bitumen (dilbit) emulsions. A microfluidic extensional flow device (MEFD) was used to determine the IFT of the dilbit - water emulsion system for bitumen concentrations of 33%, 50% and 67% by weight (solvent to bitumen ratio (S/B) = 2, 1 and 0.5, respectively) and two different pH values of water: 8.3 and 9.9. The IFT was observed to increase with the bitumen concentration, and decrease significantly upon lowering the water pH. The time scale for achieving the steady state IFT increased with bitumen concentration, and was less sensitive to the water pH. But the most important feature of our measurements is that the IFTs recorded here were several times smaller than the values reported in the literature. We recognized two important differences between our studies and prior investigations: measurement of the IFT of water drops in dilbit as opposed to dilbit drops in water in earlier studies, and time scales of measurement of IFT that ranged from hundreds of milliseconds to a few seconds, as compared to a minute or longer in past investigations. These differences were examined carefully, but neither was found to explain the low IFTs measured in our studies. Our work leads to the following hypothesis: the mechanical properties of a sheared water-bitumen interface are significantly different from a stagnant one.
Stroke Patients’ Experiences in an Adaptive Healing Room in a Stroke Rehabilitation Unit

Objectives: This study evaluated the user experiences (UX) of stroke patients residing in the adaptive healing room (AHR) and compared them to the UX of patients residing in standard private rooms (SPRs). Background: Healing environments in healthcare settings can promote patients’ healing processes, outcomes, and psychological well-being. The AHR was designed as a healing environment for stroke patients and has been previously evaluated in laboratory settings. This study was the first to evaluate it in its intended context—a stroke rehabilitation unit. Methods: The UX of 10 patients residing in the AHR and 15 patients residing in SPRs were collected via structured interviews with a set of open-ended questions and analyzed using quantitative and qualitative methods. Results: The AHR design features (orientation screen, skylight, and nature view) were rated positively by most patients. The skylight emerged as the least favorable. Responses to open-ended questions revealed that UX may be further improved if patients have more control over some of the settings (e.g., light intensity and nature views), and if the system allowed for more stimulation for patients at later stages of their recovery. Additionally, the results suggest that patients in the AHR have better UX than patients in the SPRs. Conclusion: The AHR has the potential to improve UX in the stroke rehabilitation unit. Patient feedback can be used to refine the AHR before carrying out clinical trials to assess the effect of the AHR on patient outcomes (e.g., sleep, mood, and length of stay) and stroke recovery.