Miracle-dz/UniFAR-FTUs huggingface dataset:
Effects of a Eucaloric Low Glycemic Index Diet on Insulin Sensitivity and Intramyocellular Lipid Content in Adults with Abdominal Obesity

Individuals with abdominal obesity are at higher risk for developing type 2 diabetes, predisposing cardiovascular events and insulin resistance. Low glycemic index (GI) diets may be beneficial in the management of insulin resistance. Insulin resistance is associated with increased intramyocellular lipid (IMCL) content as measured by proton nuclear magnetic resonance spectroscopy (1H-MRS). The primary objective of this thesis was to determine whether a low GI diet can improve insulin sensitivity by reducing IMCL of skeletal muscle. One hundred and twenty-one male and female participants aged 30 to 70 years (mean+SD, 53+10)) with abdominal obesity, entered a 4 to 6 week weight-maintaining, low-fat dietary advice run-in phase. Of the 121 eligible participants, 95 completed the run-in phase and were randomly assigned to either a low-GI (LGID, n=48) or high-GI diet (HGID, n=47) for 24 weeks. Participants underwent a 75g oral glucose tolerance test (OGTT) and had soleus-muscle IMCL measured by 1H-MRS at the beginning and end of the intervention period. Insulin sensitivity was assessed by the homeostatic model assessment index (HOMA) and the insulinogenic index (ISI) was calculated for insulin secretion. At the end of the run-in phase, there were significant reductions in serum total-, LDL-, and HDL-cholesterol (all, p<0.0001) and an increase in fasting plasma glucose (p<0.05). In 57 participants who wore a continuous glucose monitoring system for 24 hours during the run-in period, a total of 30% (p<0.001) of the variation in the incremental area under the blood glucose curve after self-selected breakfast meals was explained by GI. After 24 weeks, diet GI was significantly lower in the LGID than HGID group (55.5+3.1 vs 63.9+3.1, p<0.0001). Plasma glucose 60 minutes after the OGTT was significantly lower on the LGID than at baseline (p<0.05) and there was a non-significant trend towards an increase in ISI (p=0.07). On the HGID, ISI increased significantly from baseline (p<0.01). It is concluded that the LGID reduced 60 minute plasma glucose but did not significantly affect IMCL or insulin sensitivity in individuals with abdominal obesity. %%%%PhD
Capnography in the Emergency Department

1Emergency Medicine Department, Tabriz University of Medical Sciences, Daneshgah Street, Tabriz 51664, I.R, Iran 2Cardiovascular Research Center, Tabriz University of Medical Sciences, Daneshgah Street, Tabriz 51664, I.R, Iran 3Students Research Committee, Tabriz University of Medical Sciences, Tabriz, Iran 4Heart and Stroke Foundation of Canada (HSFO), Toronto, Canada 5Sunny brook hospital, University of Toronto (UoT), Toronto, Canada
Product pricing process implementation in gaming industry for a mobile application

Nowadays many businesses face the problem of pricing their products properly, mainly due to the fact that existing theoretical knowledge is complicated to employ for a particular product, nevertheless, pricing should be treated sincerely, as it handles a deep research on intercompany collaboration, classifies product’s competitive advantages, moreover, reveals and manages issues for further product development. Mobile application gaming industry is changing rapidly nowadays, appending more difficulties to pricing model implementation, therefore, two research questions were formulated, where (a) was to scrutinize pricing models for a gaming industry, and (b) was to determine a pragmatic way for implementing pricing model for a case company. The theoretical base as a secondary data encompassed key concepts and previous research findings of pricing process generally and from the mobile application field perspective. Primary data was assembled though 6 semi-structured interviews with local companies and online feedback survey with 50 respondents in total. After the saturation point of the interviews was reached and the surveys were conducted; results were manuscript, inspected and reported according to guidelines. Action research was used as an approach for answering the research questions, moreover, the triangulation of data analysis merged qualitative and quantitative research method for reliable and versatile results. Mixed method authorized a relevant way of particular pricing model implementation in a case company. What is more, suggestions for future product improvements were specified and portrayed, in order to arise growth potential and customer satisfaction. The findings provided support to disparate earlier theories and employed previous theoretical studies for the case company pricing model. As a result, a pragmatic and germane implementation of pricing process into the case company was delivered. Keywords/tags (subjects) Pricing model, pricing process, pricing strategies, gaming industry, mobile application, product pricing, mobile game, educational game
Serum Low Density Lipoprotein and Serum High Sensitive C - Reactive Protein as a Diagnostic Markers for Acute Coronary Syndrome

Background: Acute coronary syndrome (ACS) remains the major cause of mortality and morbidity in the worldwide. Low density lipoprotein- cholesterol (LDL-C) level is a major risk factor for the development of ACS, and pathogenesis of atherosclerosis. Atherosclerosis is a multi-step disease and characterized by chronic low-grade vascular inflammation, which plays a role in its every stage from onset, progression and finally to plaque rupture then triggers ACS. Elevation of high Sensitive C-reactive protein (hs-CRP) is a strong and independent pre­dictor of cardiovascular disease. The objective of this work was to evaluate the role of serum LDL-C and serum hs-CRP in patients with ACS. Patients and Method: The current study enrolled 45 patients with confirmed ACS and 30 apparently healthy persons of matching age and sex as control group. The patients were subdivided into three subgroups each one included 15 patients: Subgroup A: ST-segment elevation myocardial infarction (STEMI). Sub-group B: Non–ST-segment elevation myocardial infarction (NSTEMI), Subgroup C: Unstable angina pectoris (UAP). All patients and control groups were subjected to measurement of low density lipoprotein- cholesterol (LDL-C), high density lipoprotein- cholesterol (HDL-C), total cholesterol, triglyceride, highly sensitive CRP (hs-CRP), cardiac troponin I (cTnI), and creatine kinase-MB fraction (CK-MB), electrocardiography (ECG) and trans-thoracic-echocardiography. Results: There was highly significant increase of serum LDL-C and serum hs-CRP in group I as compared to group II (P=0.001) and significant increase of serum LDL-C ((P<0.05) and highly significant increase of serum hs-CRP (P=0.01) in STEMI and NSTEMI subgroups when compared to UAP subgroup and highly significant increase of serum LDL-C (P=0.005) and serum hs-CRP(P=0.003) in UAP sub-group when compared to group II . There was also, a positive significant correlation between serum LDL-C and both serum CK-MB and serum hs-CRP in all subgroups. Conclusion: Elevated serum LDL and hs-CRP may serve as markers of the severity of the disease which help evaluation and management of ACS patients.
MIROC-INTEG1: A global bio-geochemical land surface model with human water management, crop growth, and land-use change

Abstract. Future changes in the climate system could have significant impacts on the natural environment and human activities, which in turn affect changes in the climate system. In the interaction between natural and human systems under climate change conditions, land use is one of the elements that play an essential role. Future climate change will affect the availability of water and food, which may impact land-use change. On the other hand, human land-use change can affect the climate system through bio-geophysical and bio-geochemical effects. To investigate these interrelationships, we developed MIROC-INTEG1 (MIROC INTEGrated terrestrial model version 1), an integrated model that combines the global climate model MIROC (Model for Interdisciplinary Research on Climate) with water resources, crop production, land ecosystem, and land use models. In this paper, we introduce the details and interconnections of the sub-models of MIROC-INTEG1, compare historical simulations with observations, and identify the various interactions between sub-models. MIROC-INTEG1 makes it possible to quantitatively evaluate the feedback processes or nexus between climate, water resources, crop production, land use, and ecosystem, and to assess the risks, trade-offs and co-benefits associated with future climate change and prospective mitigation and adaptation policies.
The Performance of High-Growers and Regional Entrepreneurial Ecosystems: A Research Framework

Objective: The objective of this research is to elaborate a framework that explores the relationships between the performance of high-growth enterprises and the characteristics of regional entrepreneurial ecosystems (EEs). Research Design & Methods: This conceptual article adopts a multidimensional and profiling approach to the characteristics of EEs. The methodology is based on the combined narrative and systematic literature reviews. Findings: Five propositions as to the relationship between growth and performance of firms in the regional context, as well as to the impact of various regional profiles on the growth and profitability of firms were elaborated. The final outcome of this synthesis is a research framework. Implications & Recommendations: The implication of the proposed framework in-cludes the development of testable hypotheses for further empirical investigation. The recommendation is to adopt a profiling method of assessing the effect of EEs. Contribution & Value Added: The research contributes by setting out a direction for empirical studies that would test the impact of EE profiles and result in their quantitative taxonomies. The value added consists in reflecting the heterogeneity of EEs and their output evaluation rather than input characteristics.
Using Qualitative Research to Inform the Client-Centred Evidence-Based Practice of Occupational Therapy

Demands for increased accountability for health care expenditure, and recognition of clients' rights to interventions and methods of service delivery that are grounded in sound evidence, are compelling occupational therapists to use research findings to inform their clinical decision making. Occupational therapists also state that they embrace a client-centred orientation to practice, yet this espoused ethic seems rarely to influence decisions concerning what research is undertaken and how it is undertaken or what counts as evidence for practice. Given the widely divergent perspectives, priorities and values between health care professionals and their clients, practice based upon therapist-centred research may be neither relevant nor valid. This paper explores the philosophical underpinning of methods used to develop theory, proposing that occupational therapy's evidence-based practice must be ethically consistent with its espoused client-centred philosophy to avoid a tendency towards hypocrisy. It explores issues concerning client-centred practice and evidence-based practice and suggests that qualitative research methods may be the most appropriate tools to identify and address client priorities. While traditional quantitative research approaches render client voices silent, qualitative methods may enable occupational therapists to explore the complexities of clinical practice and of living with a disability, thereby informing a more client-centred, evidence-based practice of occupational therapy.
Two Resected Cases of AFP-Producing Carcinoma of the Lung.

要 旨:AFP産 生 肺癌 は,本 邦 で 自験例 を含 め40例 の報告 が あ るが,今 回,我 々 は術後10年 以上 の生 存例 を経験 したの で,そ の予 後 を中心 に検討 した. 症 例1は,55歳 男性. 他 疾 患観 察 中 に右 下 肺 野 の異常 影 を指 摘 され,気 管支 鏡 検 査 で 大細 胞 癌 と診 断 され た. 血 清 中 AFP値 は32000ng/mlと 高値 を示 してい た. 右 中下 葉切 除 を行 い,術 後11年 目の現在,非 担癌 生存 中 であ る. 症例2は,57歳 男性. 咳,疾 を主訴 に左下 肺 野の 異常影 を指 摘 され,針 生検 で腺 癌 と診 断 され た. 血 清 中AFP値 は3140ng/mlで,左 肺 全摘 を行 い,術 後2年6カ 月 目の現在, 非 担癌生 存 中 であ る. 両 症例 とも,病 理 病期 は1期 で,免 疫 組織 学的 に腫 瘍細 胞 内にAFP の局 在 が証 明 され た. AFP産 生 肺癌 は,そ の特徴 として 男性 に 多 く,組 織 型 では腺癌,分 化 度 では低分 化 な も のに 多 くみ られた. 手 術症 例 にお いて は,治 癒 切 除 が行 われ た場 合 は,良 好 な予後 も期 待 しうる と考 え られた. 〔肺 癌35(7):937~942,1995〕
The effect of childhood brain tumours on the child and family: a prospective multidisciplinary follow up of children with intracranial tumours.

This paper compares parentand self-report health-related quality of life (HRQL) in children aged 2–16 years with brain tumours, one, six and twelve months after diagnosis with matched normal controls. HRQL was assessed using the PedsQL generic core scales. 37 tumour patients and 42 controls were included in analysis of parent-report, and 27 patients and 31 controls in self-report HRQL. Parent-report scores were significantly lower in patients than controls for all PedsQL scores at all time points (max p = 0.002). Differences in self-report PedsQL between patients and controls were variable. The relationship between selfand parent-report in patients and controls was inconsistent; varied over time; and did not consistently correlate with parental depressive symptoms, suggesting parents and their children do not regard HRQL in a similar way. Prospective, longitudinal assessment of HRQL is important, but should be supplemented with other outcome measures such as health status and behaviour in this population. 2007 Elsevier Ltd. All rights reserved.
Hypertension in an Adolescent Secondary to Performance-Enhancement Supplement Use

Objective: To describe the effects of performance-enhancing supplements and caffeine on the blood pressure (BP) of an adolescent male. Case Summary: An adolescent male presented to his primary care provider for a preseason athletic physical. On physical exam, his BP was 162/90, exceeding the 99th percentile for his age. It had been elevated during the previous 2 yearly physicals. He was referred to the Pediatric Preventive Cardiology Clinic for follow-up. Illegal substance use and renal trauma were ruled out. During the evaluation, the patient acknowledged using energy drinks and performance-enhancing supplements, the majority of which were caffeine-based. His intention was to continue the use of supplements, so lisinopril was initiated. On follow-up, however, the patient reported supplement discontinuation, intermittent medication adherence, and lower home-based BP readings. He was subsequently lost to follow-up. An objective causality assessment revealed that the adverse drug event was probable. Discussion: When working with adolescent patients, it is particularly important to conduct an in-depth interview reflecting lifestyle choices. Use of performance-enhancing supplements and caffeine for adolescent athletes has been well reported in the literature. Adolescent use of supplements may be driven by misguided beliefs and lack of knowledge about potentially detrimental health effects, such as altered heart rate and elevated BP. Little evidence-based research is available to provide treatment guidance for clinicians regarding potential effects. Conclusions: A thorough patient history, including specific questions probing for any recent or chronic use of nutritional supplements, including energy drinks, will help identify substances that may contribute to BP variations. Even mild BP elevations in adolescents should lead clinicians to further investigate supplement use and include specific questions on any product use within the past 24 hours, several days, or longer. Adolescents may not consider the potential for adverse health effects when ingesting performance-enhancing supplements or energy drinks.
Growth of Rosmarinus officinalis under Drought Stress Can Evaluate Municipal Solid Waste Compost and Agricultural Waste Vermicompost

Click here and insert your abstract text. Click here and insert your abstract text. Click here and insert your abstract text. Click here and insert your abstract text. Click here and insert your abstract text. Click here and insert your abstract text. Click here and insert your abstract text. Click here and insert your abstract text. Click here and insert your abstract text. Click here and insert your abstract text. Click here and insert your abstract text. Click here and insert your abstract text. Click here and insert your abstract text. Click here and insert your abstract text. Click here and insert your abstract text. Click here and insert your abstract text. Click here and insert your abstract text. Click here and insert your abstract text. Click here and insert your abstract text. Click here and insert your abstract text. Click here and insert your abstract text Click here and insert your abstract text Click here and insert your abstract text Click here and insert your abstract text Click here and insert your abstract text Click here and insert your abstract text Click here and insert your abst © 2013Published by University of Tehran Press. All rights reserved. ARTICLE INFO Received: Received in revised form: Accepted: Available online:
Trial-Based Functional Analyses: How to Determine Results Most Effectively

Trial-based functional analyses are a way to conduct Functional Analyses (FA’s) in the natural setting and less labor intensive than FA’s conducted in contrived settings. These FA’s composed of short control and test segments, have proven to have certain advantages over other standard FA’s typically conducted. This study examined past trial-based FA’s and analyzed the data in various ways to determine the most effective way to conclude the function of a targeted behavior. The percentage of responding in test conditions, the latency of responding in test conditions, the order that trials were conducted, and effects of contingent control conditions across six different trial-based FA’s were examined. There were no clear results on the best measure to use between the percentage of responding and latency, however, results suggest that both measures could be beneficial. The order that trials are conducted showed to possibly have motivating operations on targeted behaviors in FA’s. Contingent control conditions also appeared to possibly exert control over the response of the targeted behavior. Suggestions for further research are included.
CRYPTOGRAPH KEY DISTRIBUTION WITH ELLIPTIC CURVE DIFFIE-HELLMAN ALGORITHM IN LOW-POWER DEVICES FOR POWER GRIDS

1 Brno University of Technology, Department of Telecommunications, Faculty of Electrical Engineering and Communication, Czech Republic, xfujdi00@stud.feec. vutbr.cz. 2 Escola Superior Politècnica, TCM1 planta 2 Despatx num. 9 / TCM3 planta 6 CTT, Fundació TecnoCampus Mataró-Maresme, 08302 Mataró, Spain CRYPTOGRAPH KEY DISTRIBUTION WITH ELLIPTIC CURVE DIFFIE-HELLMAN ALGORITHM IN LOW-POWER DEVICES FOR POWER GRIDS
Neonatology: Management, Procedures, On-Call Problems, Diseases, and Drugs

This book provides an essential understanding of statistical concepts necessary for the analysis of genomic and proteomic data using computational techniques. The author presents both basic and advanced topics, focusing on those that are relevant to the computational analysis of large data sets in biology. Chapters begin with a description of a statistical concept and a current example from biomedical research, followed by more detailed presentation, discussion of limitations, and problems. The book starts with an introduction to probability and statistics for genome-wide data, and moves into topics such as clustering, classification, multidimensional visualization, experimental design, statistical resampling, and statistical network analysis.
Outpatient rigid cystoscopy: Is it acceptable to women?

Objective: Flexible cystoscopy is commonly performed as an outpatient procedure whereas rigid cystoscopy is performed under general anaesthesia by urogynaecologists because of a perception that it is painful. The aim of this study is to assess women’s experience of outpatient cystoscopy (OC) with rigid cystoscope. Materials and methods: The first 56 women who attended our newly established OC service with rigid cystoscope were recruited prospectively for the study. They were requested to complete a questionnaire (with visual analogue scale) based on their expectations prior to the procedure. A post-procedure questionnaire was given to quantify their experience after the OC. Two patients were excluded from the study as they did not complete the questionnaire appropriately. Wilcoxon signed ranks test was used to compare the scores for comfort, pain and anxiety in the pre- and post-procedure questionnaires. Results: A total of 52/54 patients (96.3%) were fully satisfied at the end of the procedure as indicated in their visual analogue scale score of 10/10. Most patients found the procedure more comfortable and less painful than expected. There were no post-operative complications. Conclusion: OC with a rigid cystoscope is a well-tolerated, safe, cost-effective ambulatory service resulting in good patient experience.
Comparative efficacy of cycle-ergometry exercise and glucosamine sulphate iontophoresis in pain management of subjects with sub-acute knee osteoarthritis

Aims : Exercise and electro-analgesia are commonly used in physiotherapy practice to manage peripheral join t arthritis. Exercise is probably the least thing mos t subjects will embark on when experiencing pain es pecially at the acute and sub-acute stage. Till date, controversy s till trails which treatment technique is more super ior over the others. The primary purpose of this study was compare the e fficacy of exercise therapy and glucosamine sulphat e iontophoresis in managing pain experienced among subjects with sub-acute knee osteoarthritis. M ethods: Participants are 52 subjects with sub-acute knee osteoarthritis who were randoml y grouped into 3. Group 1 received exercise therapy and glucosamine sulphate iontophoresis while group 2 pa rticipants received glucosamine sulphate iontophore sis only. An equivalent of 3ml of glucosamine sulphate was administered for 15 minute via an Interrupted Galvanic c urrent. Group 3 subjects received exercise therapy only via cycle E rgometry. They rated pain experienced at the knee j oint on a 10-point pain scale. Both the descriptive and inferential st atistics (ANOVA) were used. Results: The result of ANOVA showed that there was no significant difference in the fin al pain (post-test) experienced between the 3 group s. Conclusion: This study concluded that combination of exercise therap y with glucosamine sulphate iontophoresis is not su perior in relieving pain better than using exercise therapy o nly, although, all the treatment techniques are eff ective in pain management.
Mining partially ordered sequential rules on unbounded data

Data mining studies how to separate useful data from the rest. Recent work in the field of Sequential Rule Mining has led to mining new types of rules, partially ordered sequential rules. However, existing approaches do not consider the case of unbounded data. With unbounded data, conventional approaches to data mining are not sufficient because they become slow as the dataset increases in size. We propose an algorithm that makes use of previous intelligence when processing new information. This requires a slight reformulation of the problem and the solution. In the end, we show that our algorithm, on average, outperforms the existing approaches when applied to unbounded data.