Miracle-dz/UniFAR-FTUs huggingface dataset:
The Bond Equity Yield Ratio

Scientists and practitioners have for decades attempted to find methods to forecast movements in the capital markets, thereby trying to find a way to outperform the market. The origins of forecasting literature investigated traditional financial and accounting ratios such as the dividend yield (D/P) and the earnings yield (E/P). A more recent development in the literature is an investigation of the information content inherent in the relationship between bond yields and equity yields. Based on the belief that government bonds and stocks are seen as competing assets by investors, a model known as the Bond Equity Yield Ratio has evolved. The BEYR compares the yields of the two assets and thus signals when the yield of one asset might be overpriced in relation to the yield of the other. The existing stream of literature has focused its attention towards mainly two capital markets, the US and the UK. Previous studies have often examined the forecasting ability by applying regression approaches or looking at extreme thresholds of the BEYR distribution, providing mixed results. Following the objectivistic path of ontology and the positivistic epistemology, the purpose of this study is to extend the existing knowledge laid out in the preceding literature. By examining the information content provided by the BEYR in the capital markets of Denmark, Finland, Norway and Sweden further evidence of its forecasting ability will be provided. Using historical data to compute the BEYR and following the switching signals provided, the performance of actively managed portfolios containing bonds or stocks will be compared to the market portfolio. Hence, this study tests the weak form of the efficient market hypothesis in Denmark, Finland, Norway and Sweden, via a deductive approach. The findings presented in this paper show that during the observation period, following a BEYR strategy would have led to excess return over the market portfolio in all four markets. Additionally, the BEYR portfolios had greater Sharpe ratios than those of the market portfolio, indicating better risk adjusted returns and thus a sounder relationship between risk and return. However, failing to be statistically significant, these results are only indications of potential positive effects of utilizing a BEYR strategy. Consequently, the weak form of the efficient market hypothesis seems to hold in the capital markets of Denmark, Finland, Norway and Sweden.
ANNALS OF ANIMAL SCIENCE

The aim of this study was to investigate the effect of hempseed cake on production traits, metabolic profile and antioxidant status of lambs. The research was conducted on 20 Merinolandschaf lambs of similar live body weight (24.03 kg ± 2.22 and 24.06 ± 1.84 kg in control and experimental group, respectively). The experiment started after the weaning of lambs at their average age of 70 days. Lambs were divided by gender (50% male: 50% female) and then allocated in two groups. The research lasted for 30 days during the fattening period. Lambs in the control group were fed with feed mixtures, where main protein source was soybean meal and extruded soybean (SB), while lambs in the experimental group were fed feed mixtures in which soybean was replaced by hempseed cake (HSC) at 12% of dry matter. Higher values of daily weight gain (P<0.05) compared to SB lambs were observed from the 15 to 30 day. HSC lambs showed no significant differences in hematology and biochemical blood parameters, except for lower (P<0.001) urea concentrations on days 15 and 30, as well as higher (P<0.05) Mg concentrations in serum on the 30 day. Hempseed cake in lambs ́ diets did not influence (P>0.05) activity of the enzymes, like AST, ALT, ALP, GGT and CK, as well as SOD and GPx enzymes, thus not affecting the antioxidant status of lambs ́ blood. Concentrations of DHA and n-3 fatty acids were higher (P<0.05) in HSC group than in SB group. The present study confirmed that the inclusion of HSC as soybean replacement up to 12% in the lambs’ diet is justified when considering production traits, metabolic profile and antioxidant status of Merinolandschaf lambs.
Identification and Characterization of a High-Affinity Saturable Binding Protein for the Carcinogen Benzo(a)pyrene1

A protein that binds the chemical carcinogen, benzo-(a)pyrene (BP), in a high-affinity and saturable manner has been identified in cell extracts from the AKR-2B mouse embryo cell line. The BP bound to the carcinogen-binding protein (CBP) was exchangeable in a time- and temperature-dependent fash ion and has a Kd of 1.8 x 10"9 M. Competitive binding studies indicate that chemical carcinogens [3-methylcholanthrene, benz(a)anthracene, dibenz(a,c)anthracene] and other inducers of aryl hydrocarbon hydroxylase (5,6- and 7,8-benzoflavone) compete to varying degrees with BP for binding. Steroids, 2,3,7,8-tetrachlorodibenzo-p-dioxin, and phÃ©nobarbitaldid not compete with BP for binding to the CBP. BP prevented the heat inactivation of CBP. Additional properties of CBP reveal it to have a Stokes' radius of 31 A, molecular weight of 61,000, frictional ratio of 1.2, an apparent isoelectric point of 5.2, and an S value of 4.8 in linear sucrose gradients. It was estimated that there are about 20,000 molecules of CBP per AKR-2B mouse embryo cell. The CBP was found in two nontransformed and one chemically transformed cell line; a fourth cell line A-431 (human vaginal carcinoma) had significantly reduced amounts of CBP.
Ryanodine Receptor Oligomeric Interaction IDENTIFICATION OF A PUTATIVE BINDING REGION*

Specific interactions between adjacent ryanodine receptor (RyR) molecules to form ordered two-dimen-sional arrays in the membrane have been demonstrated using electron microscopy both in situ , in tissues and cells, and in vitro , with the purified protein. RyR interoligomeric association has also been inferred from ob-servations of simultaneous channel gating during multi-RyR channel recordings in lipid bilayers. In this study, we report experiments designed to identify the region(s) of the RyR molecule, participating in this reciprocal interaction. Using epitope-specific antibodies, we identified a RyR tryptic fragment that specifically bound the intact immobilized RyR. Three overlapping RyR fragments encompassing this epitope, expressed using an in vitro mammalian expression system, were immunoprecipitated by RyR. To refine the binding regions, smaller RyR fragments were expressed as glutathione S -trans-ferase (GST) fusion proteins, and their binding to RyR was monitored using a “sandwich” enzyme-linked im-munosorbent assay. Three GST-RyR fusion proteins demonstrated specific binding, dependent upon ionic strength. Binding was greatest at 50–150 m M NaCl for two GST-RyR constructs, and a third GST-RyR construct demonstrated maximum binding between 150 and 450 m M NaCl. The binding at high NaCl concentration suggested involvement of a hydrophobic interaction. In silico analysis of secondary structure showed evidence of coil regions in two of these RyR fragment sequences, which might explain these
GENETIC DIFFERENCES BETWEEN SACCHAROMYCFS CARLSBFRGENSIS AND S. CFRFVISIAF II. RESTRICTION ENDONUCLEASE ANALYSIS OF GENES IN CHROMOSOME III

Chromosome III in a haploid Saccharomyces cerevisiae strain has been previously substituted for by its homeoIogue from S. carlsbergensis. With this chromosome substitution line the two homeologous chromosomes were shown to undergo crossing over only in a limited region, and to differ in nucleotide sequence at the HIS4 locus. In the present study the S. carlsbergensis chromosome III was compared to its S. cerevisiae homeologue at several additional loci. Cloned DNA from the S. cerevisiae loci HML, HIS4, LEU2, MAT and SUP-RL1 was used as hybridization probes in the analysis of nucleotide sequence homology at these loci and HMR. Virtually no differences were detected at SUP-RL1 and HMR, located in the region where the two chromosomes recombine, whereas considerable differences were found in the non-recombining part. The data are consistent with the assumption that HML, MAT and HMR of the S. carlsbergensis chromosome are organized as in S. cerevisiae. Segments X and Z1, which are involved in mating type interconversion, were closelyhomologous to their S. cerevisiae counterparts, whereas Y~t as well as sequences outside the HML and MAT cassettes were substantially different.
Force Sensitivity of the Von Willebrand Factor A2 Domain

von Willebrand factor (VWF) is a multimeric glycoprotein that critically supports platelet aggregation in hemostasis. Disordered VWF function causes both thrombotic and bleeding disorders, and genetic defects in VWF are responsible for von Willebrand’s disease (VWD), the most common inherited bleeding disorder in humans. Very large VWF multimers exhibit the greatest thrombogenic activity, which is attenuated by ADAMTS13 cleavage in the A2 domain. A2 cleavage is regulated by mechanical force, and pathologically high shear forces are known to enhance proteolysis and cause bleeding in patients. Enhanced cleavage is also described in patients with VWD 2A mutations. In contrast, VWF A2 is stabilized against cleavage by a calcium binding site within A2. Single molecule studies have demonstrated that mechanical unfolding is required for A2 cleavage to expose the scissile bond. In this dissertation, we aim to better understand the mechanosensitivity of A2 cleavage by characterizing the force sensitivity of A2 unfolding and refolding. We first characterized the interaction between VWF A2 and calcium using bulk isothermal calorimetry and thermal denaturation assays. In parallel, we used single molecule optical tweezers to characterize A2 unfolding and refolding. Calcium was found to bind A2 with high affinity, stabilize A2 against thermal denaturation, and enhance domain refolding. In contrast, we found that VWD 2A mutations destabilize the A2 domain against thermal denaturation. R1597W, the most common VWD 2A mutation, lies within the calcium binding loop and exhibited diminished calcium stabilization against thermal denaturation. Using optical tweezers, we found that R1597W also diminished A2 refolding. R1597W refolding in the presence of calcium was similar to that of wild-type A2 in the absence of calcium, suggesting that loss of calcium stabilization contributes to the disease mechanism of R1597W. Other VWD 2A mutations lying outside the calcium binding loop also destabilized A2, but retained
2011 Model-based Testing User Survey: Results and Analysis

Overview 4 Survey Highlights 4 Who is a Typical MBT User? 5 Approach 6 Call for Participation 6 Data Collection 6 Definitions 6 Representativeness 7 Survey Responses 8 Analysis and Presentation 8 User Organizations 9 What kind of organization sponsored the model-based testing project? 9 Approximately how many persons work in this organization, in total? 9 Environment and Applications 10 What was the overall process approach used for the MBT project? 10 What is the general application domain of the SUT? 10 What was the general release level of the SUT after testing was completed? 11 How is the SUT provided to end users/customers? 11 What kinds of computers are used in the SUT? 12 What is the general architecture of the SUT? 12 What OS(s) are used in the SUT? 13 In what programming language(s) is the SUT implemented? 14 Impetus and Preparation 15 What factors led to your project using MBT? 15 At what stage of MBT adoption is your organization? 16 MBT Usage and Configuration 18 What kind of MBT tools were used in the project? 18 If you used a commercial tool, which one? 18 If you used an open source MBT tool(s), please indicate which. 19 If you used an MBT tool(s) developed for use in your organization, please describe briefly. 19
Experiments on Detecting Fake News over Social Media using Machine Learning Algorithms

Spreading fake news has become a serious issue in the current social media world. It is broadcasted with dishonest intentions to mislead people. This has caused many unfortunate incidents in different countries. The most recent one was the latest presidential elections where the voters were misleading to support a leader. Twitter is a popular social media platform where it represents the gateway for real time news. We extracted real time data on multiple domains through twitter and performed analysis. The dataset was preprocessed and user verified column played a vital role. Multiple machine algorithms were then performed on the extracted features from preprocessed dataset. Logistic Regression and Support Vector Machine had promising results with both above 92% accuracy. Naive Bayes and Long-Short Term memory didn’t achieve desired accuracies. The model can also be applied to images and videos for better detection of fake news. 1
Development and validation of a questionnaire to evaluate teacher training for inclusion: the CEFI-R1

An inclusive teacher is one who considers diversity as a positive feature that enriches education and who, therefore, adapts the teaching methodologies to the learning characteristics of each one of the students and provides support to all their needs. Many research projects emphasize the idea of how students ́ success depends largely on the teachers’ preparation and their competencies and attitudes. The goal of this work is to present the review and resulting modification of an instrument to assess teacher training needs for inclusion (CEFI-R). For this purpose, we used a sample of 202 Spanish teachers with experience in all educational stages (preschool, primary and secondary education). The validation process is described (the process of item inclusion and exclusion, the factorial analysis in order to analyze the structure of the questionnaire and the internal consistency of the scale) which resulted in the development of a 19-item questionnaire grouped into 4 inclusion indicators: conception of diversity, methodology, supports and community participation. We can come to the conclusion that the CEFI-R is a multidimensional tool that allow us to analyze the main aspects in which teachers are less prepared to meet the diverse needs and characteristics of their students.
Mapping the Field of Software Security Metrics

While security, or its absence, is a property of running software, many aspects of software requirements, design, implementation, and testing contribute to the presence or absence of security in the finished product. Assessing whether a given piece of software meets a set of security objectives is a multi-dimensional problem, and we do not yet have a clear picture of all of the dimensions. The goal of this research is to support researcher and practitioner use of security measurement by cataloging available metrics, their validation, and the subjects they measure through conducting a systematic mapping study. Our study began with 1,561 papers and narrowed down to 63 papers reporting on 346 metrics. For each metric, we identify the subject being measured, how the metric has been evaluated by researcher(s), and how the metric is being used. Approximately 85% of security-specific metrics have been proposed and evaluated solely by their authors. Approximately 40% of the metrics are not empirically evaluated, and many artifacts and processes remain unmeasured. Approximately 15% of the metrics focus on the early stages of development or on testing (1.5%). At present, despite the abundance of metrics found in the literature, those available give us an incomplete, disjointed, hazy view of software security.
Interferometric processing of TanDEM-X bistatic SAR data using GAMMA – implementation outline

This article represents a showcase of two coding approaches with GAMMA, used to calculate topographic and differential phases from high resolution TanDEM-X bistatic data, provided by DLR. The first implementation approach comprises “BASH” scripting in Linux environment, having direct control of the GAMMA executables. The second approach is the utilisation of the PyroSAR framework, via GAMMA-API, in Python environment. Two spatial resolution scales are used – of 4 and 12 metres, to test the feasibility of TanDEM-X InSAR output products in mountainous forests in the rugged region. The first approach allowed thorough processing with abundant GAMMA output, whereas the high scale PyroSAR framework via GAMMA-API showed a fast implementation. Comparison over 4 and 12m spatial resolution products showed good feasibility with strong influence from topography. Intense multi-looking resolved better connection of coherence amplitude to the volume decorrelation in canopy, despite preserving high resolution reveals plenty of details in land cover. The differential height calculation, without phase unwrapping, showed its significance in data processing over mountainous regions. Intensities normalisation and terrain flattening showed good performance in both resolution scales. Finally, utilisation of GAMMA in InSAR processing of high resolution TanDEM-X bistatic SAR data showed good feasibility and flexibility to derive interferometric products.
EV3RT: A Real-time Software Platform for LEGO Mindstorms EV3

EV3RT is, to our knowledge, the (cid:12)rst RTOS-based software platform for LEGO Mindstorms EV3 robotics kit. It is faster and more suitable for developing applications with real-time requirements than other existing software platforms. In practice, EV3RT has been selected as one of the oﬃcially supported platforms of ET Robocon, a popular robot competition in Japan, since 2015 and used by many participating teams to make their robots accomplish the assigned tasks more stably and precisely. In this paper, the usage and architecture of EV3RT are (cid:12)rstly introduced. We then explain TOPPERS/HRP2 kernel, the RTOS of EV3RT, and how to use its protection functionalities to build a reliable platform. A mechanism to support dynamic module loading in a static RTOS is proposed to implement the application loader for EV3RT. Implementation techniques like approach to reusing Linux device drivers are also described. Finally, the advantages of EV3RT are shown by evaluating and comparing its performance with other platforms.
Minority Electoral Participation: Institutional Remedies against the Political Exclusion of Ethnic Minorities

In this paper, we investigated the impact of different institutions on ethnic minorities’ political participation. Based on the results of a hierarchical cross-country comparison, we found that individuals belonging to ethnic minorities were less likely to participate in national elections than members of the majority groups within the same country. We tested whether this negative effect of belonging to an ethnic minority group on political participation could be attenuated by inclusive institutions such as suffrage rights, horizontal power-sharing institutions (Proportional electoral system PR, effective proportionality, the number of government parties) or vertical power-dividing institutions in terms of federalism (subnational elections and subnational authority) attenuated the negative effect of belonging to an ethnic minority group. The results of multilevel analyses showed that suffrage rights attenuate the negative effect of minority status on political participation. In contrast, power dividing enhances the negative effect of belonging to an ethnic minority group on political participation. Posted at the Zurich Open Repository and Archive, University of Zurich ZORA URL: https://doi.org/10.5167/uzh-53654 Conference or Workshop Item Accepted Version Originally published at: Bühlmann, M; Hänni, M (2011). Minority participation: Institutional remedies against the political exclusion of ethnic minorities. In: 3-Länder-Tagung, Basel, 13 January 2011 14 February 2011.
A Correctness Model for Pipelined Microprocessors

The discussion in the last section suggests that a function mapping the state stream of a pipeline into a state stream for a non-pipelined model must collect different pieces of the pipelined state stream at different times and packag e them into a state record to appear in the non-pipelined state stream at a particular time. This section describes such an abstraction function for UiNTA. The correctness model for UINTA depends on a function, called abs that maps a pipeline model state stream into an architectural model state stream. This function allows us to maintain the illusion in the architectural model that the state changes occur in ~ single t ime step hetween times t and t + 1.
Structure Determination of Macrolactin Compounds with Antibacterial Activities Isolated from Bacillus polyfermenticus KJS-2

Isolated from Bacillus polyfermenticus KJS-2 Dong-Hee Kim, Kyung-Ran Kang, Hyun-Woo Kim, Si-Yeol Yoon, Chun-Gyu Kim, Tokutaro Yamaguchi 4 , Jae Kyung Sohng 4 and Jae Seon Kang 5 * Research and Development Center, Daewoo Pharmaceutical Co,. Ltd., Busan 603-838, Korea Technical Research Institute, Daesun Distilling Co., Ltd. Busan 619-934, Korea Department of Pharmaceutical Engineering, Inje University, Gimhae city, Gyeongnam 621-749, Korea Department of Pharmaceutical Engineering, Sun Moon University, Asan city, Chungnam 336-708, Korea Department of Pharmacy, Kyungsung University, Busan 608-736, Korea
Running title: AMMONIA DURING PREGNANCY LEADS TO COGNITIVE DAMAGE

Ammonia is involved in the pathogenesis of neurological conditions associated with hyperammonemia, including hepatic encephalopathy. Few is known about the effects of gestational exposition to ammonia in the developing brain, and the possible long-term consequences of such exposure. We aimed to evaluate the effects of ammonia exposure during the gestation and the possible long-term cognitive alterations on pups. Eight female rats were divided into two groups: (1) control (saline solution); (2) ammonia (ammonium acetate, 2,5mmol/Kg). Each rat received a single subcutaneous injection during all gestational period. The brains from 1-day-old rats were obtained to the determination of thiobarbituric acid reactive species (TBARS), protein carbonyl and nitrite/nitrate levels. Some animals were followed 30 days after delivery and were subjected to the step-down inhibitory avoidance task. It was observed a signifi cant increase in protein carbonyl, but not TBARS or nitrite/nitrate levels, in pups exposed to ammonia. Rats exposed to ammonia presented long-term cognitive impairment. Gestational exposition to ammonia induces protein oxidative damage in the neonatal rat brain, and long-term cognitive impairment.
Review on Accident Investigation and Analysis Methods

The main commonly recognized methods were generalized into five major categories based on the accident models,including Causal-sequence Model,Process Model,Energy Model,Logical Tree Model as well as SHE-management Model.At the same time,a brief description of some commonly used methods was provided,as well as a comparative analysis on them according to important characteristics.It can be concluded as follow:each of these methods has different areas of application and different qualities and deficiencies,so a generally adopted method should be suitable to the specific modes and characteristic features of a certain accident,and a combination of methods ought to be used in a comprehensive investigation of a complex accident;Methods considering the event sequences and accident factors can help reduce risk and prevent future accidents.Graphical illustrations can help not only identify information gaps but also facilitate communication among investigators;Investigators focusing on the government and the regulators in their accident investigation to a great extend need to base their analysis on experience and practical judgment,more than on results from formal analytical methods,there may be need for advanced analytic techniques to support the objectivity tasks of accident investigation.