Miracle-dz/UniFAR-FTUs huggingface dataset:
10α-Hydroxy-4,9-dimethyl-13-[(pyrrolidin-1-yl)methyl]-3,8,15-trioxatetracyclo[10.3.0.02,4.07,9]pentadecan-14-one

The title compound, C19H29NO5, was synthesized from 9α-hydroxyparthenolide (9α-hydroxy-4,8-dimethyl-12-methylene-3,14-dioxatricyclo[9.3.0.02,4]tetradec-7-en-13-one), which was isolated from the chloroform extract of the aerial parts of Anvillea radiata. The molecule is built up from two fused five- and ten-membered rings with the (pyrrolidin-4-yl)methyl group as a substituent. The two five-membered ring display the same envelope conformations, whereas the ten-membered ring adopts an approximate chair–chair conformation. The dihedral angle between the ten-membered ring and the lactone ring is 21.81 (9)°. An intramolecular O—H⋯N hydrogen bond stabilizes the molecular conformation. In the crystal, intermolecular C—H⋯O interactions link the molecules into chains parallel to the c axis.
6-Bromo-4-oxo-4H-chromene-3-carbaldehyde

In the title compound, C10H5BrO3, a brominated 3-formylchromone derivative, the non-H atoms are essentially coplanar (r.m.s. deviation = 0.0420 Å), with the largest deviation from its mean plane [0.109 (2) Å] being found for the ring-bound carbonyl O atom. In the crystal, molecules are linked through halogen bonds [Br⋯O = 3.191 (2) Å, C—Br⋯O = 167.32 (10)° and C=O⋯Br = 168.4 (2)°] along [101]. Molecules are assembled into layers parallel to (101) via π–π stacking interactions along the b axis [shortest centroid–centroid distance between the pyran and benzene rings = 3.495 (2) Å].
A focus group qualitative study of HIV stigma in the Canadian healthcare system

Stigma related to HIV in the healthcare system has a pervasive, negative impact on the mental, physical and sexual health of people living with HIV. While well-documented before the advent of antiretroviral treatment, this stigma in Canada has not been as thoroughly examined from a critical perspective since HIV’s evolution from an acute to a chronic illness. The current study examines attitudes and beliefs of healthcare providers toward people living with HIV through the use of focus groups. Focus group participants were women living with HIV, men living with HIV, medical and nursing students, and health care providers working with people living with HIV. Data analysis was conducted with a critical lens using an immersion/crystallization approach. Two broad themes emerged from the data: HIV-specific experiences, and components of stigma. Both negative and positive experiences were described. Discrimination, as a behavioural act, was deemed to be the less prevalent and often more covert expression of stigmatization. Stereotyping, including with regard to perceived sexuality, and prejudice were seen as more insidious and perpetuated by both the medical and educational establishments. These findings clearly demonstrate the need for change in terms of reducing the amount of stigma present in these complex, nuanced, and enduring relationships between people living with HIV and the health care system.
Poly[diaqua-μ2-oxalato-di-μ4-terephthalato-diytterbium(III)]

The crystal structure of the title complex, [Yb2(C8H4O4)2(C2O4)(H2O)2]n, features an extended three-dimensional framework made up of Yb3+ ions coordinated by terephthalate ligands, oxalate ligands and water molecules. The Yb3+ ion has a distorted square-antiprismatic coordination formed by one aqua ligand, two O atoms from an oxalate ligand and five O atoms belonging to four terephthalate anions. Two symmetry-independent terephthalate anions, as well as the oxalate anion, occupy special positions on inversion centers. The water molecule participates in O—H⋯O hydrogen bonding with both terephthalate anions.
1-Hydroxy-3-(3-methylbut-2-enyloxy)xanthone

In the title compound, C18H16O4, a monoprenylated xanthone, the xanthone skeleton exhibits an essentially planar conformation (r.m.s. deviation 0.0072 Å) and the isoprenyl side chain remains approximately in the mean plane of the xanthone unit, making a dihedral angle of 4.5 (2)°. The hydroxyl group forms an intramolecular O—H⋯O hydrogen bond. Moreover, there is a weak intermolecular C—H⋯O interaction between a ring C atom and the xanthene O atom. In the crystal structure, there are no intermolecular hydrogen bonds and the crystallographic packing is governed by van der Waals forces, leading to an arrangement in which the molecules assemble with their planes parallel to each other, having a separation of 3.6 (3) Å.
The effect of dignity therapy model on sense of dignity of hemodialysis patients: a randomized clinical trial

Background and Aim: Hemodialysis as a treatment for patients with chronic renal failure is stressful process that can threaten patients' sense of dignity. This research was Performed with the aim of Influence dignity therapy model on sense of dignity hemodialysis patients was conducted. Materials and Methods: this clinical trial research was carried out on 42 hemodialysis patient in hemodialysis department of Jiroft Imam Khomeini Hospital in 1391. Patients were randomly divided into two experimental groups and the control group, were obtained after informed consent forms, demographic characteristics (age, sex, occupation, education, marital status, duration of illness, history of mental illness) and human dignity questionnaire was completed. For experimental groups dignity therapy model was performed at 3 days (one day, three days ,one week), daily for 60 to 30 minutes at the bedside of his condition. Again after compeletion of the treatment questionnaire were completed for experimental groups and during the same period for the control group. Then data were analyzed using spss19 statistical software. Results: Data analysis showed, in the post-test in experimental group, the mean of sense of dignity was (37/19 ± 12/72). There was no significant difference in our research between the average of sense of dignity in the experimental and control groups in pre-test (p 0.05) and both groups were almost identical Before performing the model but there was a meaningful difference between the average of sense of dignity in the experimental and control groups (p 0.05). Between age, sex, occupation, education, marital status, duration of illness with patient's sense of dignity, after performing the model in the experimental groups, there is no significant difference. Conclusion: the dignity therapy model is effect in increases sense of dignity of hemodialysis patients. It is recommend to be thought of measures to implement the model for patient.
2-{2-[3-(1H-Benzimidazol-2-yl)quinolin-2-yloxy]ethoxy}ethanol

In the title compound, C20H19N3O3, the interplanar angle between the benzimidazole unit and the quinoline unit is 25.1 (2)°. Two different hydrogen bonds involving the hydroxy group and the imidazole unit are present. An intramolecular N—H⋯O hydrogen bond links the hydroxy group of the side chain with the imidazole unit, forming a 12-membered ring, and an intermolecular O—H⋯N hydrogen bond links the molecules, forming chains in the crystallographic b direction.
4-(3-Chlorophenyl)-3-[(2,6-difluorobenzyl)sulfanyl]-5-(3,4,5-trimethoxyphenyl)-4H-1,2,4-triazole

In the title compound, C24H20ClF2N3O3S, the essentially planar triazole ring (r.m.s. deviation = 0.001 Å) forms dihedral angles of 22.35 (10), 68.17 (10) and 42.01 (10)° with the mean planes of the trimethoxyphenyl, chlorophenyl and difluorophenyl rings, respectively. A weak intramolecular C—H⋯π interaction occurs. In the crystal, molecules are linked into sheets lying parallel to the bc plane by C—H⋯O and C—H⋯N hydrogen bonds. The crystal packing also features weak C—H⋯π interactions.
3-Chloropyridin-2-amine

In the title compound, C5H5ClN2, a by-product in the synthesis of ethyl 2-(3-chloropyridin-2-yl)-5-oxopyrazolidine-3-carboxylate, the amine groups form intermolecular hydrogen-bonding associations with pyridine N-atom acceptors, giving centrosymmetric cyclic dimers. Short intermolecular Cl⋯Cl interactions [3.278 (3) Å] also occur.
A Descriptive Study of the Leadership Role of Community Health Ambassadors on Diabetes-Related Health Behaviors

Diabetes is a chronic disease that bears a disproportionate burden among African American populations. The lack of access to affordable, culturally appropriate health care is a key barrier to effective diabetes prevention or disease management for racial/ethnic minority populations. Living in public housing communities, with concentrated poverty, exacerbates the burden of diabetes and reduces access to screening and early detection services to prevent the onset of diabetes. The purpose of the study was to describe the leadership role of lay health advisors, known as Community Health Ambassadors (CHAs), on diabetes-related health behaviors of African Americans living in a public housing authority (PHA) community in one city in Southeastern North Carolina. The research sample included CHAs (n = 17) and the PHA residents (clients; n = 62) participating in the pilot Community Health Ambassador Program (CHAP). A mixed methods research design was used to describe the outreach services provided by CHAs and explore associations between outreach and diabetes-related health behaviors among the clients they served. Analyses included secondary quantitative data and primary qualitative focus group data from CHAs and clients. The results of this one sample design pilot study indicated that it is feasible to implement CHAP in public housing communities. While the study’s findings suggest there is no association between CHA outreach and clients’ health behaviors, the leadership roles of the CHAs are demonstrated. Preliminary data were suggestive, but not significant for key clinical outcomes and health behaviors. From the perspectives of CHAs and their clients, the CHAP was beneficial to them and their community. The study underscores the need for future research to examine the leadership roles of racial/ethnic minorities as partners in community-based programs with a focus on eliminating health disparities.
3-Ethyl-1H-1,2,4-triazole-5(4H)-thione

The molecule of the title compound, C4H7N3S, exists as the thione tautomer in the solid state. The asymmetric unit consits of one molecule in which all atoms are located on a crystallographic mirror plane. In the crystal, adjacent molecules are linked by N—H⋯N and N—H⋯S hydrogen bonds into chains running along the a axis. π–π stacking interactions between the triazole rings [centroid–centroid distance = 3.740 (1) Å and interplanar distance = 3.376 Å] may further stabilize the structure.
2-(4-Carboxypiperidinium-1-yl)pyridine-3-carboxylate

The title compound, C12H14N2O4, crystallizes as a zwitterion. A negative charge is delocalized in the deprotonated carboxyl group attached to the pyridine ring. The piperidine N atom accepts a proton and the ring is transformed into a piperidinium cation. There is an intramolecular N—H⋯O hydrogen bond between the protonated NH and a carboxylate O atom. In the crystal, an O—H⋯O hydrogen bond between the carboxyl group and the carboxylate O atom of another molecule generates a helix along the b axis.
Guide to antimicrobial therapy in the adult ICU 2012

Sepsis still remains one of the commonest cause of ntensive care admission here in Malaysia. In the last six years following the first edition, there has been burgeoning increase in knowledge and usage of antimicrobials. However the pressing issues of growing antimicrobial resistance, inappropriate therapy and escalating cost compel for a more responsible prescriber. In order to keep pace with important advances, most chapters have been revised and others eliminated. The objective of this book has not strayed from its original purpose that is to provide a quick and comprehensive guide for the Malaysian doctors caring for the critically ill. The structure has been kept to facilitate easy bedside referencing. The notations have expanded to explain the rationale behind antibiotic choices. Hence we hope this handbook will add to the armamentarium of those who work in intensive care units. The first revision of the ‘The MSA Guide to Antimicrobial Therapy in the Adult ICU’ has been assumed by the Malaysian Society of Intensive Care. This guide has been a culmination of many hours of evidence review and exchange of opinions. Putting it together to cater to our local needs have been a challenge for us. We would like to thank our external reviewers for their invaluable input and also acknowledge the contribution of the working committee of the first edition: it is on the foundation of their work that the present,Second edition has been developed.
3α-Dimethylamino-20-(N-methylacetamido)pregn-5-ene

The title compond, C26H44N2O, is an steroidal alkaloid isolated from the medicinally important plant Sarcococca saligna. The molecule consists of four fused rings (A–D), having chair, half-chair, chair and envelope conformations, respectively. The dimethylamino group is axially oriented on ring A, whereas the (N-methylacetamido)ethyl group is attached equatorially on ring D. The crystal structure is stabilized only by van der Waals forces.
2-Methoxy-4-[(4-methylpiperazin-1-yl)iminomethyl]phenol

The title compound, C13H19N3O2, was obtained by the direct solvent-free reaction of 4-hydroxy-3-methoxybenzaldehyde with 1-amino-4-methylpiperazine. The piperazine ring adopts a chair conformation. In the crystal, strong intermolecular O—H⋯N and weak intermolecular C—H⋯O and C—H⋯N hydrogen bonds help to establish the packing.
Consequences of Job Insecurity on the Mental Health and Well-Being of Employees

Globalization, outsourcing, subcontracting, downsizing and economic recession have collectively conspired to increase the number of employees experiencing persistent job insecurity in Nigeria. The consequences of such a situation are numerous. Millions of employees are constantly passing through sleepless nights and heartpounding days, only finding solace in sleeping pills with attendant risks of coronary heart disease and sudden death due to fears of job insecurity. This paints a picture of what employees suffer when they live in constant fear that tomorrow’s pay slip may be their last. There is no disputing the fact that job insecurity is eroding the quality of life of many generally. Its prolonged effects can lead to premature deaths. In this paper, some practical suggestions are offered on how employees can cope with the challenges of job insecurity.
Dichloridobis(3-chloropyridine-κN)zinc

In the crystal structure of the title compound, [ZnCl2(C5H4ClN)2], discrete complex molecules are found in which the ZnII cations are coordinated by two chloride anions and the N atoms of the two 3-chloropyridine ligands within a slightly distorted tetrahedron. Moreover, intermolecular C—Cl⋯Cl—C halogen interactions (Cl⋯Cl = 3.442 Å) are found between the building blocks.
(E)-3-(4-Chlorophenyl)-1-(1-naphthyl)prop-2-en-1-one

In the title compound, C19H13ClO, the benzene ring and the naphthalene system, are twisted by 12.3 (3) and 36.1 (2)°, respectively, and in opposite directions with respect to the central propenone bridge. The bond-angle pattern within the benzene ring is influence by both substituents; these influences are almost additive. In the crystal, the molecules are linked by C—H⋯O and C—H⋯Cl interactions.
1-(2-Hydroxyethyl)pyrrole-2,5-dione

The asymmetric unit of the title compound, C6H7NO3, contains two molecules (A and B) related by a non-crystallographic twofold pseudo-axis. The molecules are joined in the (AABB)n manner by O—H⋯O hydrogen bonds between their hydroxy groups, thus forming C(2) chains along the a-axis direction. Neighboring molecules of the same kind (A and A, or B and B) are related by inversion centers, so that all hydroxy H atoms are disordered other two sets of sites with half occupancies (superimposed O—H⋯O and O⋯H—O fragments). The molecules are further linked by C—H⋯O interactions, which can be considered to be weak hydrogen bonds.
1-Iodotriptycene

The title compound, C20H13I, is a halogenated derivative of triptycene. The molecule shows crystallographic as well as non-crystallographic C 3 symmetry. The asymmetric unit comprises one third of the molecule. Dispersive I⋯I contacts [I⋯I = 3.6389 (3) Å] connect the molecules into dimers. The shortest centroid–centroid distance between two π-systems is 3.8403 (12) Å.
4-Amino-3-phenyl-1H-1,2,4-triazole-5(4H)-thione

In the title compound, C8H8N4S, the planar triazole ring forms a dihedral angle of 13.7 (2)° with the phenyl ring. The crystal structure is stabilized by intermolecular N—H⋯S hydrogen-bond interactions, linking the molecules into chains along the a axis.
(E)-N′-(3-Ethoxy-4-hydroxybenzylidene)-4-methoxybenzohydrazide

In the molecule of the title benzohydrazide derivative, C17H18N2O4, the dihedral angle between the benzene rings is 6.86 (11)°. The methoxy group of the 4-methoxyphenyl fragment deviates slightly [Cmethyl—O—C—C = 10.0 (4)°] with respect to the benzene ring, whereas the ethoxy group of the 3-ethoxy-4-hydroxyphenyl fragment is is almost coplanar [C—O—C—Cmethyl = 178.5 (2)°]. In the crystal, molecules are linked by N—H⋯O, O—H⋯O and C—H⋯O hydrogen bonds into a two-dimensional network parallel to the ab plane. C—H⋯π interactions and C⋯O [2.980 (3) Å] short contacts are also observed.
A randomized Comparison of C-MAC Videolaryngscope Versus Macintosh Laryngoscope for Tracheal Intubation

Purpose: The present study compared the C-MAC videolaryngoscope (C-MAC) with Macintosh laryngoscope with regard to the laryngoscopic view, laryngoscopic time and time required to complete the tracheal intubation. We aimed to investigate any disadvantages that the C-MAC laryngoscope may have when used in routine clinical practice. Methods: Ninety patients undergoing elective surgery requiring general anaesthesia and tracheal intubation were randomly allocated to receive tracheal intubation using the C-MAC or the Macintosh laryngoscope. Following a standardised general anaesthetic, data were collected during laryngoscopy and endotracheal intubation. Results: The median laryngoscopic time (IQR) for the C-MAC and Macintosh laryngoscope respectively were 9.8 (4) and 8.1 (3.3) seconds (p = 0.037). The median total intubation time (IQR) for the C-MAC and Macintosh laryngoscope respectively were 29.2 (18.6) and 23.5 (9.4) seconds, (p = 0.011). There were no significant differences in the laryngoscopic view, additional airway manoeuvres and success rate of tracheal intubation between the two groups. Conclusion: Although the differences in the laryngoscopic time and intubation time were statistically significant, they did not achieve clinical significance. Therefore we conclude that the C-MAC videolaryngoscope may be used in routine clinical practice for tracheal intubation.
1-{2-[(4-Chlorobenzylidene)amino]phenyl}-3-phenylthiourea

The asymmetric unit of the title compound, C20H16ClN3S, contains two independent molecules, A and B. In molecule A, the dihedral angles between the central benzene ring and the pendant chlorobenzene and phenyl rings are 6.37 (15) and 64.79 (15)°, respectively. The corresponding values in molecule B are 28.21 (14) and 82.11 (16)°, respectively. Each molecule features an intramolecular N—H⋯N hydrogen bond, which generates an S(5) ring. In the crystal, molecules A and B form dimers, being linked by two N—H⋯S hydrogen bonds with graph-set notation R 2 2(8).
Ammonia–triphenylborane

The asymmetric unit of the title compound, C18H18BN or (C6H5)3B·NH3, comprises two crystallographically independent but virtually identical molecules. Molecules of one type are linked with each other by N—H⋯π interactions, generating an infinite column aligned along the b-axis direction. The columns of different types of molecules are interconnected by C—H⋯π interactions, producing a three-dimensional array.
(2-Aminophenyl)methanol

The crystal strucure of the title compound, C7H9NO, displays N—H⋯O hydrogen bonds which link molecules related by translation along the b axis, and O—H⋯N and further N—H⋯O hydrogen bonds which link molecules related by the 21 screw axis along the c axis. The resulting combination is a hydrogen-bonded layer of molecules parallel to (011).
3-Phenyl-1H-pyrrolo[2,1-c][1,4]oxazin-1-one

The molecule of the title compound, C13H9NO2, is slightly twisted with a dihedral angle of 4.85 (9)° between the nine-membered ring system and the phenyl ring. The nine non-H atoms of the 1H-pyrrolo[2,1-c][1,4]oxazin-1-one system are coplanar [r.m.s. deviation = 0.0122 (2) Å]. In the crystal, weak intermolecular C—H⋯O interactions link molecules into chains along [10]. The crystal studied was an inversion twin with a 0.48624 (9):0.51376 (9) domain ratio.
1-Methyl-3-phenylthiourea

The title compound, C8H10N2S, was prepared by reaction of methylamine solution, KOH and phenyl-isothiocyanate in ethanol. It adopts a syn-Me and anti-Ph conformation relative to the C=S double bond. The dihedral angle between the N—C(=S)—N thiourea and phenyl planes is 67.83 (6)°. In the crystal, the molecules centrosymmetrical dimers by pairs of N(Ph)—H⋯S hydrogen bonds. The dimers are linked by N(Me)—H⋯S hydrogen bonds into layers parallel to (100).
O uso da termografia infravermelha na avaliação do retorno ao trabalho em programa de reabilitação ampliado (PRA)

Em certas ocasiões, mesmo com tratamento corretamente instituído em pacientes com lesões por esforços repetitivos/distúrbios osteomusculares relacionados ao trabalho (LER/DORT), depara-se com situações de difícil julgamento quanto ao retorno ao trabalho. Muitas vezes por uma queixa persistente de não melhora dos sintomas ou quando associado a outras comorbidades, como síndrome fibromiálgica. O objetivo deste estudo foi comparar os padrões térmicos encontrados com a avaliação pericial de retorno ao trabalho de pacientes acometidos por LER/DORT, por meio de avaliação clínica e termográfica duplo-cega. Foram avaliados 128 pacientes, acometidos por LER/DORT de uma empresa do setor da agroindústria- frigorífico, onde um grupo de 62 pacientes foi selecionado para perícia quanto ao retorno ao trabalho. Destes, 3,2% tiveram retorno imediato ao trabalho, 77,4% afastamento por 60 dias, 6,4%, afastamento por 6 meses e 12,9% aposentadoria por invalidez. As alterações térmicas tiveram direta correlação com a classificação de retorno às atividades realizadas pelos peritos, segundo critérios de número de lesões, natureza etiológica, diferencial térmico e índice termográfico para síndrome fibromiálgica. A termometria cutânea por termografia infravermelha demonstrou-se como método complementar útil e objetivo no apoio a avaliação pericial para definição de capacidade ou incapacidade para o trabalho.
2-Acetylhydrazono-2-phenylacetohydrazide

The title compound, C10H12N4O2, was prepared as an intermediate for the synthesis of metamitron. The benzene ring plane forms dihedral angles of 66.0 (1) and 3.5 (5)° with the hydrazine plane and the acetylimino plane, respectively. The crystal structure involves intermolecular N—H⋯O hydrogen bonds.