Miracle-dz/UniFAR-FTUs huggingface dataset:
Cognitive Antihyperlipidemic and Antioxidant Activities of Bitter leaf ( amygdalina) and Scent leaf (

Oxidative stress manifests an imbalance in the production and the detoxification of free radicals. Free radicals cause oxidative degradation of biomolecules like lipids, proteins, nucleic acids, and carbohydrate molecules, thereby and leading to health deterioration from a range of metabolic anomalies that cause diseases and ailments including cardiovascular diseases (CVD), hypertension, stroke and cancer. Both bitter leaf (VA) and Scent leaf different cultures.The addition of scent leaf as additive in preparation of delicacies in Nigeria has prompted this study to determine the cognitive activities of both plants to repair the damag as their antioxidant potentials. The results obtained revealed that both plants have antioxidant abilities when subjected to standard antioxidant evaluations although significantly higher (p that the antioxidant potentials of VA was depressed on the addition of OG. The results obtained from the modulation of lipid in albino rats challenged with hyp that both VA and OG have a positive effect to lower LDL C thus potentiating their antidyslipidemic ability and protective role against dyslipidemic disorders. Similarly, the cognitive effect showed reductio activity of OG was boosted. The high phospholipid contents of the selected tissues upon treatments with the leaf extracts also showed that both VA and OG can have ameliorating effects on coronary heart disease, inflammat It is noteworthy that both VA and OG have good potential in the ability to reverse induced dyslipidemia and in spontaneous cellular lipid, while the addition causes a reduction in the activities of VA.
The right mindset: stress mindset moderates the association between perceived stress and depressive symptoms

ABSTRACT Background and Objectives: Having a stress-is-enhancing mindset – the extent to which one believes the effects of stress are enhancing rather than debilitating – is associated with greater health and well-being, and may mitigate negative outcomes associated with experiencing stress. The present study aimed to examine stress mindset and whether it moderates the association between perceived stress and mental health outcomes. Design and Methods: Participants (N = 293) completed questionnaires assessing their stress mindset, perceived stress level, and current depressive and anxiety symptoms. Perceived stress and mental health were assessed again at a follow-up session one month later. Results: Across moderated linear regression analyses, there was a consistent pattern in which higher perceived stress was associated with higher mental health concerns, but the risk was greater for those with a stress-is-debilitating mindset. Stress mindset moderated the perceived stress-depression association at baseline (p = .026), at follow-up (p = .008), and when focusing on change in depressive symptoms from baseline to follow-up (p = .006). Conclusions: These results suggest that a stress-is-enhancing mindset mitigates the development of depressive and anxiety symptoms in college students faced with high levels of stress. The benefits of introducing emerging adults to an adaptive stress mindset are discussed.
Claudin-4 induction could improve the homing and anti-fibrotic effect of bone marrow mesenchymal stem cells (BM-MSCS) in thioacetamide induced liver fibrosis in rats

Homing and migration of bone marrow mesenchymal stem cells (BM-MSCs) to a target tissue has been a major concern because, only few cells reach the target tissue and remain there after systemic administration. The current study aimed at investigating the potential hepatoprotective role of claudin-4 in improving the homing and antifibrotic effect of BM-MSCs. In our study, Sprague-Dawley rats were randomly divided into six groups: Control group; Meloxicam group; Thioacetamide group; Thioacetamide + BM-MSCs group; Meloxicam + Thioacetamide group; Thioacetamide + Meloxicam + BM-MSCs. Flowcytometry, Western Blot, hematoxylin and eosin (H&E), Masson’s trichrome staining, immunohistochemical studies for the detection of α-Smooth muscle actin (α-SMA) and enzyme-linked immunosorbent assay (ELISA) were involved to measure different parameters. Results showed that in vivo BM-MSCs administration significantly improved histopathological changes and attenuated the elevated liver enzymes, lipid peroxidation marker malondialdehyde (MDA), inflammatory cytokine levels including tumor necrosis factor alpha (TNF-α), cyclooxygenase 2 enzyme (COX-2) enzyme, nuclear factor kappaB (NF-κB) and both hydroxyproline content and α-SMA were also reduced. Additionally, there was an increase in the activity of reduced glutathione (GSH) in liver tissue. Moreover, the PKH26 staining showed that meloxicam which induced the expression of claudin-4 resulted in more homing of BM-MSCs to the liver more than those without meloxicam addition. In conclusion, the present study demonstrated improved homing and anti-fibrotic effect of BM-MSCs, which is thought to be partly mediated by the overexpression of claudin-4 by meloxicam.
Physically Crosslinked Poly (Vinyl Alcohol)/Kappa-Carrageenan Hydrogels: Structure and Applications

This paper discusses the structure morphology and the thermal and swelling behavior of physically crosslinked hydrogels, obtained from applying four successive freezing–thawing cycles to poly (vinyl alcohol) blended with various amounts of κ-carrageenan. The addition of carrageenan in a weight ratio of 0.5 determines a twofold increase in the swelling degree and the early diffusion coefficients of the hydrogels when immersed in distilled water, due to a decrease in the crystallinity of the polymer matrix. The diffusion of water into the polymer matrix could be considered as a relaxation-controlled transport (anomalous diffusion). The presence of the sulfate groups determines an increased affinity of the hydrogels towards crystal violet cationic dye. A maximum physisorption capacity of up to 121.4 mg/g for this dye was attained at equilibrium.
A Novel Approach of Fuzzy Logic Based Edge Detection for Coronary Angiogram Using Virtual Instrumentation

Arteriosclerosis is a coronary artery disease (CAD) that is caused due to the deposition of plaque in the walls of arteries by which the arteries narrows down (stenosis) and the blood flow gets restricted. Computed Topographic angiography (CTA) has been used in clinical diagnosis and it is very difficult to visualize the blood vessels and the stenosis due to the presence of bones and tissues. This paper proposes an approach of fuzzy logic based edge detection to detect the edges of the coronary artery. The proposed method is compared with Roberts, Prewitt, Sobel and canny edge operators and the simulation results reveals that the proposed method gives better edges than the other method. The analysis of the proposed method has been evaluated on various CT angiography images qualitatively using Laboratory virtual instrument engineering workbench (Lab VIEW) software environment.
A Theoretical Study on Lithium Storage Capability of (10, 0) Zigzag Carbon Nanotube

We studied the Lithium storage capability of (10, 0) zigzag carbon Nanotubes by using Ab initio calculations. The main motivation is to use single walled carbon Nanotubes (SWCNTs) to store lithium atoms. By using first principles calculations, the storage of Lithium atoms on the CNT has been studied by considering both inside and outside cases. The band structure, density of states, electron density and was performed by inserting Li atoms. The binding energies are also calculated. We observed that the adsorption of lithium atoms on the outside of the CNT is favored in contrast to the inside.
Humanistic caring, a nursing competency: modelling a metamorphosis from students to accomplished nurses.

BACKGROUND Most nursing regulatory bodies expect nurses to learn to be humanistic and caring. However, the learning process and the developmental stages of this competency remain poorly documented in the nursing literature. METHODS The study used interpretive phenomenology, and 26 participants (students and nurses) were individually interviewed. Benner's (1994) method was adapted and concretised into a five-phase phenomenological analysis to assist with intergroup comparisons. RESULTS Critical milestones and developmental indicators were identified for each of the five stages of the 'humanistic caring' competency. Satisfaction and meaning at work seemed closely connected to the development of 'humanistic caring'. Links emerged between the development of 'humanistic caring' and three other competencies. CONCLUSIONS Nurse educators might insist on the fact that 'humanistic caring' goes beyond nurse-patient communication and that it is integrated in nursing care. The findings highlight that nurses' working conditions should be improved in order to uphold humanistic caring after graduation.
Specific Substitutions in Region V2 of gp120 env confer SHIV Neutralisation Resistance

A tier 2 SHIV-MK38 strain was obtained after two in vivo passages of tier 1 SHIV-MK1. SHIV-MK38#818, cloned from the MK38 strain, was neutralisation-resistant, like the parental MK38 strain, to SHIV-infected monkey plasma (MP), HIV-1-infected human pooled plasma (HPP), and KD247 monoclonal antibody (mAb) (anti-V3 gp120 env). We investigated the mechanisms underlying the resistance of #818, specifically the amino acid substitutions that confer resistance to MK1. We introduced amino acid substitutions in the MK1 envelope by in vitro mutagenesis and then compared the neutralisation resistance to MP, HPP, and KD247 mAb with #818 in a neutralisation assay using TZM-bl cells. We selected 11 substitutions in the V1, V2, C2, V4, C4, and V5 regions based on the alignment of env of MK1 and #818. The neutralisation resistance of the mutant MK1s with 7 of 11 substitutions in the V1, C2, C4, and V5 regions did not change significantly. These substitutions did not alter any negative charges or N-glycans. The substitutions N169D and K187E, which added negative charges, and S190N in the V2 region of gp120 and A389T in V4, which created sites for N-glycan, conferred high neutralisation resistance. The combinations N169D+K187E, N169D+S190N, and N169D+A389T resulted in MK1 neutralisation resistance close to that of #818. The combinations without 169D were neutralisation-sensitive. Therefore, N169D is the most important substitution for neutralisation resistance. This study demonstrated that although the V3 region sequences of #818 and MK1 are the same, V3 binding antibodies cannot neutralise #818 pseudovirus. Instead, mutations in the V2 and V4 regions inhibit the neutralisation of anti-V3 antibodies. We hypothesised that 169D and 190N altered the MK1 Env conformation so that the V3 region is buried. Therefore, the V2 region may block KD247 from binding to the tip of the V3 region.
High Temperature Structural Transformation Studies in Magnetite Nanoparticles

In this paper magnetite nanoparticles were prepared by co-precipitation method. Ferrite nanoparticles are characterized by thermogravimetric and differential thermal analysis (TG–DTA). The crystalline structure of magnetite nanoparticles were studied by means of Xray diffraction (XRD). The samples show cubic inverse spinel structure with size ranging from 9 to 26 nm. The effect of the high-temperature heat treatment on carrier transfer in spinel structure of magnetite and nonmagnetic modification has been investigated.
Immersion of Achilles tendon in phosphate‐buffered saline influences T1 and T2* relaxation times: An ex vivo study

Robust mapping of relaxation parameters in ex vivo tissues is based on hydration and therefore requires control of the tissue treatment to ensure tissue integrity and consistent measurement conditions over long periods of time. One way to maintain the hydration of ex vivo tendon tissue is to immerse the samples in a buffer solution. To this end, various buffer solutions have been proposed; however, many appear to influence the tissue relaxation times, especially with prolonged exposure. In this work, ovine Achilles tendon tissue was used as a model to investigate the effect of immersion in phosphate‐buffered saline (PBS) and the effects on the T1 and T2* relaxation times. Ex vivo samples were measured at 0 (baseline), 30 and 67 hours after immersion in PBS. Ultrashort echo time (UTE) imaging was performed using variable flip angle and echo train‐shifted multi‐echo imaging for T1 and T2* estimation, respectively. Compared with baseline, both T1 and T2* relaxation time constants increased significantly after 30 hours of immersion. T2* continued to show a significant increase between 30 and 67 hours. Both T1 and T2* tended to approach saturation at 67 hours. These results exemplify the relevance of stringently controlled tissue preparation and preservation techniques, both before and during MRI experiments.
Complete Genome Sequence of an Alphabaculovirus from Choristoneura diversana

The genome sequence of a baculovirus isolated from Choristoneura diversana is 122,827 bp long and contains 150 putative open reading frames (ORFs). The virus is closely related to alphabaculoviruses isolated from insect species of the genus Choristoneura. ABSTRACT The genome sequence of a baculovirus isolated from Choristoneura diversana is 122,827 bp long and contains 150 putative open reading frames (ORFs). The virus is closely related to alphabaculoviruses isolated from insect species of the genus Choristoneura.
Recognition of Handwritten Mathematical Tex

The recognition of handwritten mathematical documents is a very important field which is interested in identifying the text, graphics or notations and in extracting information. In this paper the focus will be on the handwritten mathematical text recognition and we are going to present all the necessary steps in our system (preprocessing, text lines segmentation, mathematical symbols segmentation and symbols recognition).
FACTORS INFLUENCING CUSTOMER SATISFACTION TOWARDS SUPERMARKETS IN THAI NGUYEN CITY, VIETNAM

The study attempts to find out the determinants of customer satisfaction towards supermarkets in Thai Nguyen city. In this study 200 responses of the 4 selected supermarkets in Thai Nguyen city were surveyed by convenient method. From the literature review and expert opinion, it has been found out that the dimensions of customer satisfaction are based on: product, price, personal interaction, convenience, services and physical appearance. Regression Analysis was used to identify the impact of these factors on customer satisfaction. The research findings showed that product, price, personal interaction, convenience, services and physical appearance were positively impacted on customer satisfaction towards studied supermarkets. Among them price had a strongest influence on customer satisfaction. Based on these findings, some recommendations were proposed.
Mosquito larvicidal activity of seaweeds extracts against Anopheles stephensi , Aedes aegypti and Culex quinquefasciatus Mohamed

Mosquito larvicidal activity of seaweeds extracts against Anopheles stephensi, Aedes aegypti and Culex quinquefasciatus Mohamed Yacoob Syed Ali, Sundaram Ravikumar, Johanson Margaret Beula PG & Research Department of Biotechnology, Mohamed Sathak College of Arts and Science, Sholinganallur, Chennai-600119, Tamil Nadu, India School of Marine Sciences, Division of Marine Microbiology and Medicine, Department of Oceanography and Costal Area Studies, Alagappa University, Thondi Campus, Thondi-623409, Tamil Nadu, India Department of Chemistry, Scott Christian College (Autonomous) Nagercoil, Tamil Nadu, India Asian Pac J Trop Dis 2013; 3(3): 196-201
Judging Relative Onsets and Offsets of Audiovisual Events

This study assesses the fidelity with which people can make temporal order judgments (TOJ) between auditory and visual onsets and offsets. Using an adaptive staircase task administered to a large sample of young adults, we find that the ability to judge temporal order varies widely among people, with notable difficulty created when auditory events closely follow visual events. Those findings are interpretable within the context of an independent channels model. Visual onsets and offsets can be difficult to localize in time when they occur within the temporal neighborhood of sound onsets or offsets.
Developing a strategic understanding of telehealth service adoption for COPD care management: A causal loop analysis of healthcare professionals

Background Telehealth services can improve the quality of health services for chronic obstructive pulmonary disease (COPD) management, but the clinical benefits for patients yet not clear. It is crucial to develop a strategy that supports the engagement of healthcare professionals to promote the sustainable adoption of telehealth services further. The aim of the study was to show how variables related to the perception of telehealth services for COPD by different healthcare professionals interact to influence its adoption and to generate advice for future telehealth service implementation. Methods Data was thematically synthesized from published qualitative studies to create causal loop diagrams, further validated by expert interviews. These diagrams visualize dependencies and their polarity between different variables. Results Adoption of telehealth services from the nurse’s perspective is directly affected by change management and autonomous decision making. From the physician’s perspective, perceived value is the most important variable. Physical activity management and positive user experience are considered affecting perceived value for physiotherapists. There is no consensus where self-management services should be positioned in the COPD care pathway. Conclusion Our results indicate how complex interactions between multiple variables influence the adoption of telehealth services. Consequently, there is a need for multidimensional interventions to achieve adoption. Moreover, key variables were identified that require attention to ensure success of telehealth services. Furthermore, it is necessary to explore where self-management services are best positioned in the care pathway of COPD patients.
ALGORITHM FOR BIOMETRIC DETECTION APPLICATION TO IRIS

Biometric system is a technology for identification or authentication of a living person grounded on a behavioral or physiological characteristic. There are so many biometric systems like fingerprints, voice, gait, iris etc. Other identification systems are available like PIN, password etc Among these biometric authentication system, iris identification has got increasing tending due to its high accuracy and reliability. Iris recognition system is based on pattern recognition techniques which are based on characteristics of iris. In this paper, an algorithm based on Iris biometric is proposed. The system takes the biometric data CASIA version 1.0. This algorithm gives the more accuracy.
Imaging of the immune system – towards a subcellular and molecular understanding

ABSTRACT Immune responses involve many types of leukocytes that traffic to the site of injury, recognize the insult and respond appropriately. Imaging of the immune system involves a set of methods and analytical tools that are used to visualize immune responses at the cellular and molecular level as they occur in real time. We will review recent and emerging technological advances in optical imaging, and their application to understanding the molecular and cellular responses of neutrophils, macrophages and lymphocytes. Optical live-cell imaging provides deep mechanistic insights at the molecular, cellular, tissue and organism levels. Live-cell imaging can capture quantitative information in real time at subcellular resolution with minimal phototoxicity and repeatedly in the same living cells or in accessible tissues of the living organism. Advanced FRET probes allow tracking signaling events in live cells. Light-sheet microscopy allows for deeper tissue penetration in optically clear samples, enriching our understanding of the higher-level organization of the immune response. Super-resolution microscopy offers insights into compartmentalized signaling at a resolution beyond the diffraction limit, approaching single-molecule resolution. This Review provides a current perspective on live-cell imaging in vitro and in vivo with a focus on the assessment of the immune system. Summary: This Review provides a current perspective on live-cell imaging in vitro and in vivo with a focus on the understanding of the immune system at the subcellular and molecular level.
Hardware Implementation of an Adaptive Mixed Signal Neuro Fuzzy System Using High Speed and Low Power Analog CMOS Circuits

In this paper we design of an adaptive Nero fuzzy system with mixed-signal inputs and digital outputs. In this paper analog advantages including low die area, high speed and simplicity are added to the digital advantages, such as programmability, robust against noise and distortions. a new programmable Fuzzifier circuit based on mixed-signal input, and min circuit for inference and Multiplier/Divider circuit for defuzzifier block and a current mode high speed flash Analog to Digital (A/D) converter with 4bit resolution are proposed. The inference speed of the system is about 18.18 MFLIPS. The controller simulated in 0.35um CMOS standard technology.
Medical Marijuana Laws and Driving Under the Influence of Marijuana and Alcohol.

BACKGROUND AND AIMS Medical marijuana law (MML) enactment in the US has been associated with increased cannabis use but lower traffic fatality rates. We assessed the possible association of MML and individual-level driving under the influence of cannabis (DUIC), and also under the influence of alcohol (DUIA). DESIGN AND SETTING Three cross-sectional U.S. adult surveys: The National Longitudinal Alcohol Epidemiologic Survey (NLAES; 1991-1992), the National Epidemiologic Survey on Alcohol and Related Conditions (NESARC; 2001-2002), and the NESARC-III (2012-2013). PARTICIPANTS The total n was 118,497: 41,764, 41,184 and 35,549 from NLAES, NESARC, and NESARC-III. MEASUREMENTS Across the three surveys, similar questions in the Alcohol Use Disorder and Associated Disabilities Interview Schedule assessed DUIC and DUIA. Ever-MML states enacted MML between 1991-1992 and 2012-2013 (overall period). Early-MML states enacted MML between 1991-1992 and 2001-2002 (early period). Late-MML states enacted MML between 2001-2002 and 2012-2013 (late period). MML effects on change in DUIC and DUIA prevalence were estimated using a difference-in-differences specification to compare changes in MML and other states. FINDINGS From 1991-1992 to 2012-2013, DUIC prevalence nearly doubled (from 1.02% to 1.92%), increasing more in states that enacted MML than other states (difference-in-differences [DiD]=0.59%; 95%CI=0.06%-1.12%). Most change in DUIC prevalence occurred between 2001-2002 and 2012-2013. DUIC prevalence increased more in states that enacted MML 2001-2002 to 2012-2013 than in never-MML states (DiD=0.77%; 95%CI= -0.05%-1.59%), and in two early-MML states, California (DiD=0.82; 95%CI=0.06-1.59) and Colorado (DiD=1.32; 95%CI=0.11-2.53). In contrast, DUIA prevalence appeared unrelated to MML enactment. CONCLUSIONS Medical marijuana law enactment in US states appears to have been associated with increased prevalence of driving under the influence of cannabis, but not alcohol.