Miracle-dz/UniFAR-FTUs huggingface dataset:
Effects of Frequency Allocations and Zero-Dispersion Frequencies on FDM Lightwave Transmission Systems

In long-haul frequency-division-multiplexing lightwave transmission systems, transmission characteristics are degraded by four-wave mixing (FWM) generated in optical fibers. To overcome this problem, modified repeated unequally spaced (RUS) allocations such as equally spaced RUS (ERUS) and unequally spaced RUS (URUS) allocations have already been examined. In addition, it has been shown that FWM noises decrease by separating signal frequencies and a zero-dispersion frequency in equally spaced (ES) allocations. In this paper, ES, ERUS, and URUS allocations are studied from the viewpoint of the position of the zero-dispersion frequency relative to the signal frequencies. It is revealed that FWM noises are reduced in ES, ERUS, and URUS, with an increase in the separation between the signal frequencies and the zero-dispersion frequency, and FWM noises in ERUS and URUS are much lower than FWM noises in ES.
Effects of Methylenetetrahydrofolate Reductase and Reduced Folate Carrier 1 Polymorphisms on High-Dose Methotrexate-Induced Toxicities in Children With Acute Lymphoblastic Leukemia or Lymphoma

The authors investigated whether high-dose methotrexate-induced toxicity differed according to the presence of methylenetetrahydrofolate reductase (MTHFR) or reduced folate carrier 1 (RFC1) genetic polymorphism. The authors studied 15 children with acute lymphoblastic leukemia or lymphoblastic lymphoma who were treated using protocols that included high-dose methotrexate (3.0 g/m2), for an overall total of 43 courses. Methotrexate-induced toxicities and the plasma methotrexate concentrations were evaluated retrospectively. Hematologic toxicity was the most frequently observed toxicity, appearing in 87% of the patients. In a subset of patients (47%), elevation of liver transaminase levels showed a repeated tendency to develop. High plasma methotrexate concentrations at 48 hours after the methotrexate infusion were not significantly related to methotrexate-induced toxicities except for mucositis. A generalized estimating equation analysis revealed that vomiting during the high-dose methotrexate treatment was more pronounced in patients who had a larger number of G alleles at the RFC1 80G>A polymorphism. No significant differences in the development of other toxicities or in the plasma methotrexate concentrations were observed for the different MTHFR 677C>T or RFC1 80G>A polymorphisms. This study suggests but does not prove that the RFC1 80G>A polymorphism may contribute to interindividual variability in responses to high-dose methotrexate.
Combined linear interpolated channel estimation and block equalization over HF channels

In this paper, a new channel estimation method combined with block equalization for a block transmission system over time-varying HF channels is presented. The channel impulse response (CIR) is approximated as a linear function of the time variable. With the help of training sequence inserted in the front and the end of data symbols, the time-varying CIR can be derived by linear interpolation. Based on the estimated CIR, the data symbols subject to the inter-symbol interference (ISI) can be easily recovered by block equalization rapidly. It can be seen from the simulation results that the proposed method is able to track the time-varying channel well, and a moderate bit-error-rate performance is achieved with a low complexity.
Spatio-temporal dynamics of kind versus hostile intentions in the human brain: An electrical neuroimaging study

Neuroscience research suggests that inferring neutral intentions of other people recruits a specific brain network within the inferior fronto-parietal action observation network as well as a putative social network including brain areas subserving theory of mind, such as the posterior superior temporal sulcus (pSTS), the temporo-parietal junction (TPJ), and also the anterior cingulate cortex (ACC). Recent studies on harmful intentions have refined this network by showing the specific involvement of the ACC, amygdala, and ventromedial prefrontal cortex (vmPFC) in early stages (within 200 ms) of information processing. However, the functional dynamics for kind intentions within and among these networks remains unclear. To address this question, we measured electrical brain activity from 18 healthy adult participants while they were performing an intention inference task with three different types of intentions: kind, hostile and non-interactive. Electrophysiological results revealed that kind intentions were characterized by significantly larger peak amplitudes of N2 over the frontal sites than those for hostile and non-interactive intentions. On the other hand, there were no significant differences between hostile and non-interactive intentions at N2. The source analysis suggested that the vicinity of the left cingulate gyrus contributed to the N2 effect by subtracting the kindness condition from the non-interactive condition within 250–350 ms. At a later stage (i.e., during the 270–500 ms epoch), the peak amplitude of the P3 over the parietal sites and the right hemisphere was significantly larger for hostile intentions compared to the kind and non-interactive intentions. No significant differences were observed at P3 between kind and non-interactive intentions. The source analysis showed that the vicinity of the left anterior cingulate cortex contributed to the P3 effect by subtracting the hostility condition from the non-interactive condition within 450–550 ms. The present study provides preliminary evidence of the spatio-temporal dynamics sustaining the dissociation between the understandings of different types of social intentions.
Detection of PF4-heparin Auto-antibodies by ELISA

aggregating activity of the thienopyridine clopidogrel. Biochem Pharmacol 1992; 44: 527-32. 4. Savi P, Combalbert J, Gaich C, Rouchon MC, Maffrand JP, Berger Y, Herbert JM. The antiaggregating activity of clopidogrel is due to a metabolic activation by hepatic cytochrome P450-1A. Thromb Haemost 1994; 72: 313-7. 5. Defreyn G, Gachet C, Savi P, Driot F, Cazenave JP, Maffrand JP. Ticlopidine and clopidogrel (SR 25990C) selectively neutralize ADP inhibition of PGE1-activated platelet adenylate cyclase in rats and rabbits. Thromb Haemost 1991; 65: 186-90. 6. Holme S, Sixma JJ, Wester J, Holmsen H. ADP-induced refractory state of platelets in vitro. II-Functional and ultra studies on gel filtered platelets. Scand J Haematol 1977; 18: 267-78. 7. Mills DCB, Puri R, Hu C-J, Minniti C, Grana G, Freedman MD, Colman RF, Colman RW. Clopidogrel inhibits the binding of ADP analogues to the receptor mediating inhibition of platelet adenylate cyclase. Arteriosclerosis and thrombosis. 1992; 12: 430-6. 8. Savi P, Laplace MC, Maffrand JP, Herbert JM. Binding of H-2-methylthio ADP to rat platelets: effect of clopidogrel and ticlopidine. J Pharm Exp Ther 1994; 269: 772-7. 9. Gambino MC, Passaghe S, Chen ZM, Bucchi F, Gori G, Latini R, De Gaetano G, Cerletti C. Selectivity of oral aspirin as an inhibitor of platelet vs. vascular cyclooxygenase activity is reduced by portacaval shunt in rats. J Pharmacol Exp Ther 1988; 245: 287-90. 10. Savi P, Pereillo JM, Fedeli O, Maftouh M, Uzabiaga MF, Berger Y, Necciari J, Rouchon MC, Combalbert J, Picard C, Maffrand JP, Pascal M, Herbert JM. Structure and Activity of the Active Metabolite of Clopidogrel. Submitted.
ECMO IN THE NEWBORN

Since the first use in neonates in 1974, extracorporeal membrane oxygenation (ECMO) has been a life-saving technology for newborns with respiratory and cardiac failure. ECMO has been used to treat a variety of cardio-respiratory problems, including meconium aspiration syndrome (MAS), persistent pulmonary hypertension of the neonate (PPHN), congenital diaphragmatic hernia (CDH), sepsis, and cardiac anomalies. For this group of high-mortality neonates, ECMO has produced a survival of 76% in all newborns treated. This review article will examine the current selection criteria for ECMO, the clinical management of neonates on ECMO and discuss the long-term outcome of neonates treated with ECMO.
Channel Estimation With Expectation Maximization and Historical Information Based Basis Expansion Model for Wireless Communication Systems on High Speed Railways

This paper proposes a blind channel estimator based on expectation maximization algorithm and historical information-based basis expansion model for uplink wireless communication systems on high speed railways. The information of basis matrices is obtained from the uplink data of the past trains at the base station (BS). With the known basis matrices at the BS, our suggested estimator can estimate the basis coefficients and recover the channel parameters without requiring training symbols. The modified Cramer–Rao bound is derived for the estimated basis coefficients and the computational complexity of the proposed estimator is analyzed. Numerical results are then provided to corroborate our studies. It is shown that the proposed estimator outperforms existing data-aided estimators, including least square and linear minimum mean square error.
Survey Near infrared face recognition : A literature survey

Sajad Farokhia,b,∗, Jan Flussera, Usman Ullah Sheikhc a Institute of Information Theory and Automation, Czech Academy of Sciences, 18208, Prague 8, Czech Republic b Faculty of Computer Engineering, Najafabad Branch, Islamic Azad University, 85141-43131, Najafabad, Iran cDigital Signal and Image Processing Research Group, Faculty of Electrical Engineering, Universiti Teknologi Malaysia, 81310, Johor, Malaysia
Adherence Inhibition of Streptococcus mutans: an Assay Reflecting a Possible Role of Antibody in Dental Caries Prophylaxis

Adherence of cariogenic streptococci to the smooth surfaces of teeth has been shown to lead to plaque formation and ultimately to caries production. This adherence can be reproduced in vitro and requires sucrose in the growth media. The work reported here describes the development of an assay based on the ability of immune rabbit serum to inhibit adherence of Streptococcus mutans 6715 to glass surfaces. Rabbits were immunized with Formalin-killed whole bacteria. Sera were titered for adherence inhibition and bacterial agglutination. The former assay was found to be dependent upon immunoglobulin G (IgG) antibody, whereas the latter detected either IgG or IgM antibodies. These two assays appeared to detect different antigens. It was hypothesized that the adherence inhibition assay detects antibody directed against an enzyme, perhaps dextransucrase, responsible for dextran synthesis, since immune serum was found to inhibit incorporation of radiolabel from 14C-sucrose into cell wall extract. The adherence inhibition assay has potential application for study of other cariogenic bacteria. Studies are being pursued in the hope that this assay may lead to a means of control of dental caries.
Hepatorenal Syndrome

Acute kidney injury (AKI) secondary to hepatorenal syndrome (HRS) is an ominous complication of end-stage liver disease (ESLD). In HRS, splanchnic and peripheral vasodilatation with reduction in effective arterial volume causes activation of mechanisms leading to intense renal vasoconstriction and functional AKI. HRS is a diagnosis of exclusion and all other causes of AKI (especially prerenal azotemia) have to be considered and excluded. Spontaneous bacterial peritonitis (SBP) frequently precipitates HRS and should be ruled out in all ESLD patients presenting with AKI. Prompt therapy of SBP with intravenous antibiotics and albumin lessens the risk of developing HRS. Combined use of intravenous albumin, splanchnic and/or peripheral vasoconstrictors, and renal replacement therapy (RRT) are only bridges to early liver transplantation (or combined liver-kidney transplantation in selected patients). Transplantation is the only definitive way of improving the long-term prognosis. Close collaboration between hospitalists/internists managing HRS patients and hepatology and nephrology consultants is critically important.
Incremental Matrix Factorization: A Linear Feature Transformation Perspective

Matrix Factorization (MF) is among the most widely used techniques for collaborative filtering based recommendation. Along this line, a critical demand is to incrementally refine the MF models when new ratings come in an online scenario. However, most of existing incremental MF algorithms are limited by specific MF models or strict use restrictions. In this paper, we propose a general incremental MF framework by designing a linear transformation of user and item latent vectors over time. This framework shows a relatively high accuracy with a computation and space efficient training process in an online scenario. Meanwhile, we explain the framework with a low-rank approximation perspective, and give an upper bound on the training error when this framework is used for incremental learning in some special cases. Finally, extensive experimental results on two real-world datasets clearly validate the effectiveness, efficiency and storage performance of the proposed framework.
Satsisfiability and Systematicity

We introduce a new notion of systematicity for satisfiability algorithms with restarts, saying that an algorithm is strongly systematic if it is systematic independent of restart policy but weakly systematic if it is systematic for some restart policies but not others. We show that existing satisfiability engines are generally only weakly systematic, and describe FLEX, a strongly systematic algorithm that uses an amount of memory polynomial in the size of the problem. On large number factoring problems, FLEX appears to outperform weakly systematic approaches.
A New Dynamic SGS Model for Large Eddy Simulation of Particle-Laden Turbulent Flows

Abstract : The paper presents a new dynamic SGS model of two-way coupling for large eddy simulation of particle-laden turbulent flow. The advantage of this new model is that coupling of fluid-particles SGS components was taken into account and at the same time the coefficient of proposed SOS model can be optimized by Germano's (1991) dynamic procedure. To investigate the capability of this model, numerical simulations of particle-laden turbulent flow at Re=644 in a vertical channel were performed using this new dynamic SGS model. By comparing the calculation results with that using single-phase SGS models which didn't consider coupling of SGS components the role of particles SGS components played in the turbulence modulation of fluid flow was clarified for particle-laden channel turbulent flows. In addition, the subgrid-scale stresses obtained using the proposed model vanish at wall boundary, and have the correct asymptotic behavior in the near-wall region of the turbulent boundary.
Approximate Query Answering with Frequent Sets and Maximum Entropy

To instantiate this scheme, we combine two general and useful techniques: the summary information provided by frequent sets [1] and the probabilistic estimation principle of maximum entropy [2]. Our approximation method is as follows. Given the table r, we rst compute the collection C of frequent sets of r for some suitable threshold . This is the summary of the data from which we compute the approximate answers. Given an arbitrary query ' over the table, let S be the set of attributes that occur in '. We nd from C all frequent sets that are included in S, and construct the maximum entropy distribution on S using those frequent sets as constraints. Then, we evaluate ' on the maximum entropy distribution and give the answer as the approximate answer. This approach is useful for any type of queries: as we construct the distribution on S, we can compute ' on that distribution regardless of what the actual form of ' is. The complexity of the method is independent of the size of the data (after the initial computation of the frequent sets), linear in the number of frequent sets contained in S, and exponential in j S j, the number of variables occurring in the query. Thus the method is useful for any size of data and very tolerant of the number of constraints. The main limitation of the method is the exponentiality in the number of variables occurring in the query, limiting its application in practice to queries involving no more than 10 variables.
Tissue and serum lipidome shows altered lipid composition with diagnostic potential in mycosis fungoides

Mycosis fungoides (MF) is the most common type of cutaneous T cell lymphoma. In this study, we used matrix-assisted laser desorption/ionization-Fourier transform ion cyclotron resonance mass spectrometry (MALDI-FTICR–MS) to perform lipidomic profiling of 5 MF tissue samples and 44 serum samples (22 from MF patients and 22 from control subjects). Multivariate statistical analysis of the mass spectral data showed that MF tissues had altered levels of seven lipids and MF sera had altered levels of twelve. Among these, six phosphotidylcholines, PC (34:2), PC (34:1), PC (36:3), PC (36:2), PC (32:0), and PC (38:4) and one sphingomyelin, SM (16:0) were altered in both MF tissues and sera. PC (34:2), PC (34:1), PC (36:3), and PC (36:2) levels were increased in both tissues and sera from MF patients, whereas SM (16:0), PC (32:0), and PC (38:4) levels were increased in MF sera but were decreased in MF tissues. We have thus identified multiple lipids that are altered in MF tissues and sera. This suggests serological and tissue lipidomic profiling could be an effective approach to screening for diagnostic biomarkers of MF.
ALPHA1-PROTEINASE INHIBITOR (A1PI) THERAPY FOR THE PREVENTION OF BRONCHOPULMONARY DYSPLASIA (BPD) IN PREMATURE INFANTS. • 1466

Background/Objectives: An imbalance between increased neutrophil elastase and a decreased antiprotease shield has been suggested as a factor contributing to the development of BPD. We hypothesized that administration of exogenous A1PI to premature neonates would inhibit neutrophil elastase and attenuate the development of BPD. Methods: A randomized, placebo-controlled, prospective study of A1PI (Prolastin/Bayer) supplementation was performed. Neonates less than 24 hours of age with birth weights 600-1000 g on respiratory support, and 1001-1250 g with respiratory distress syndrome (RDS) were eligible. A1PI (60 mg/kg IV) or placebo was infused on Days 0, 4, 7 and 14. Primary outcome was BPD in survivors, defined as oxygen requirement on Day 28. Results: 106 patients were recruited. There were no significant differences between groups in birth weight, gestational age, sex ratio or incidence of RDS. Status on Day 28 and incidence of intraventricular and pulmonary hemorrhage (IVH & PH) are shown below. Statistical analysis is by chi-squared test. A1PI therapy significantly reduced the incidence of PH (p=.03, RR.22, CI.05-.98). The incidence of BPD in survivors was lower in the treated group but the difference did not reach statistical significance (p=.06, RR.79, CI.60-1.02). No side effects were noted other than a trend towards increased total, but not severe IVH. Conclusion: A1PI therapy appears to reduce the incidence of PH and may impede the development of BPD in some neonates born prematurely. Further work on dosage, timing and adjunctive therapies is indicated. (Funding received from Bayer/CRCS R&D Fund)Table
Coral mucus bacteria as a source for antibacterial activity

In the oligotrophic marine environment there are ecological niches rich in nutrients and diverse in bacterial populations. One such niche is the coral surface mucus layer. Interactions amongst microorganisms found in coral mucus may be symbiotic or competitive; competing over space and food. It has been hypothesized that the microbial communities found on the coral surface may play a role in the coral's defense, possibly through the production of antimicrobial substances. To find potentially active compounds produced by coral-mucus bacteria, over 200 selected microorganisms isolated from the mucus layer of a number of coral species were grown using agar plating technique. Screening for antibacterial substances was performed using overlay and drop techniques, and antibacterial activity was tested against indicator microorganisms. Results indicate that more than 20% of cultivable mucus-associated bacteria originating from hard corals demonstrated antibacterial activity. Isolates obtained from hard corals demonstrated higher percentage of activity than soft corals' isolates. Isolates related to the genera Vibrio and Pseudoalteromonas demonstrated high activity against both gram-positive and gram-negative bacteria. These results demonstrate the existence of microorganisms with antibacterial activity on the coral surface, indicating that they may play a role in protecting the coral host against pathogens.
Flux estimation by asymmetric carrier injection for sensorless direct torque control of PMSM

The combination of direct torque control and permanent magnet synchronous motors (PMSMs) provides a highly dynamic drive. In this paper direct torque control method of PMSM is merged with a sensorless control algorithm and a robust flux observer is proposed which results in a high performance highly reliable drive. First a high frequency signal injection method within DTC algorithm is introduced to estimate the rotor position of PMSM. Then the method is modified in order to estimate stator dynamic inductances. The stator inductances are then used in a current model flux observer.
Scalable delta-sigma modulator readout architecture for array-based sensor system

A scalable and modular delta-sigma modulator readout architecture and an implementation for an array-based sensor system are presented. The proposed readout system has parallel finite impulse response (FIR) filters that are one-to-one mapped to a large-scale array of delta-sigma modulators. The proposed filter uses bit-serial arithmetic, and it provides simultaneous and continuous filtering and readout capability to double the effective sample rate with a single concurrent conversion and readout phase. The oversampling rate and the filter coefficients can be adjusted flexibly to the design needs, and the filter array size can be increased modularly with a minimal additional circuits. A prototype filter module with a 255-tap FIR filter shows maximum 95MSamples/sec in 0.18 mum CMOS technology, and an array of 256 filter modules produces 377kFrames/sec. A filter module is about 145 mum wide and 7.45 mum high
Corporate social responsibility : a resource-based view of the firm

This paper reviews the application of the corporate social responsibility (CSR) as an intangible dynamic resource, its application in the formulation of marketing strategies and its association with business performance, using the theoretical framework of resource-based view of the firm (RBV). The study aims to address the control and governance of the application of the CSR with respect to self-control and regulatory control of corporate compliance. A model of CSR is suggested that represents the predictors of the construct (CSR) to facilitate the test of its usefulness in explaining the extent to which organisations may choose to be socially responsible.