Miracle-dz/UniFAR-FTUs huggingface dataset:
Enabling semantic queries across federated bioinformatics databases

Motivation Data integration promises to be one of the main catalysts in enabling new insights to be drawn from the wealth of biological data available publicly. However, the heterogeneity of the different data sources, both at the syntactic and the semantic level, still poses significant challenges for achieving interoperability among biological databases. Results We introduce an ontology-based federated approach for data integration. We applied this approach to three heterogeneous data stores that span different areas of biological knowledge: 1) Bgee, a gene expression relational database; 2) OMA, a Hierarchical Data Format 5 (HDF5) orthology data store, and 3) UniProtKB, a Resource Description Framework (RDF) store containing protein sequence and functional information. To enable federated queries across these sources, we first defined a new semantic model for gene expression called GenEx. We then show how the relational data in Bgee can be expressed as a virtual RDF graph, instantiating GenEx, through dedicated relational-to-RDF mappings. By applying these mappings, Bgee data are now accessible through a public SPARQL endpoint. Similarly, the materialised RDF data of OMA, expressed in terms of the Orthology ontology, is made available in a public SPARQL endpoint. We identified and formally described intersection points (i.e. virtual links) among the three data sources. These allow performing joint queries across the data stores. Finally, we lay the groundwork to enable nontechnical users to benefit from the integrated data, by providing a natural language template-based search interface. Project URL http://biosoda.expasy. org, https://github.com/biosoda/bioquery
Estimation of Machinery Weights of the Medium and Small-sized Ships

For preliminary estimation of ships' machinery weights, many papers giving well-judged data and discussions for rational method of estimation, such as [1], [2], [3], [4], [5], [6], are available, however, they are mostly concerned with large ships propelled by power more than about 2, 000 horsepower. Regarding the medium and small-sized ships, as far as the author is aware, fragmental data and vague discussions found in various technical literature are the all available. In this paper, available data concerned with machinery weights of commercial ships propelled by direct-drive diesel plants of power below 3, 000 horsepower with single screw propeller are collected and analysed to obtain systematic data Fig. 1 and Fig. 2 as weight to power ratio versus power per shaft diagrams together with suplementary data Fig. 1 and Fig. 3. Influences of various factor such as revolutions per minute, mean effective pressure, type and construction of the main units on machinery weights are also investigated in detail to give a better guidance for logical and rational utlization of the proposed diagrams in preliminary estimation of machinery weights.
"Correlation of Albumin-Bilirubin (ALBI) Score with Child-Turcotte-Pugh (CTP) Score in the Evaluation of Liver Cirrhosis "

Cirrhosis of liver is characterized by the replacement of normal liver tissue by scar tissue. The Child-Turcotte-Pugh (CTP) score is used to assess the prognosis of cirrhosis and included five factors: total bilirubin level, serum albumin, prothrombin time, ascites and hepatic encephalopathy. CTP score depends on clinical assessment which may result variation in scoring. Recently a new score is introduced, Albumin-Bilirubin (ALBI) score which may be done instead of CTP scoring in cirrhotic patient. This cross sectional study was conducted at the Department of Laboratory Medicine in collaboration with the Department of Hepatology, BSMMU, Dhaka, from March 2018 to February 2019. Blood samples were assayed from eighty one diagnosed cirrhotic patients. For all statistical analysis SPSS version 22 was used. The mean age of the study group was 46.1±16.0 years. 64.2% were male and 35.8% were female. Kappa (k) value was 0.759 between ALBI and CTP score. Pearson's correlation coefficient (r) test showed significant strong positive correlation between CTP score and ALBI score (r=+0.853, p<0.001). This study concluded that the ALBI score may be done alternative to the CTP score in cirrhotic patient because it’s simple, two parameters only, more evidence based and more objective.
Data Association and Prediction for Tracking Multiple Objects

Objectives: Tracking moving objects is essential for high level computer vision analysis, like object behavior interpretation or gait recognition etc. In this paper, a new method to track multiple moving objects in the surveillance video sequence is proposed. Methods/Statistical Analysis: Object tracking is done by extracting color moments feature from the segmented foreground object and associating individual objects in the successive frames using nearest neighbor classifier and Chi- Square dissimilarity measure. Further, object tracking during occlusion has been addressed by predicting the missing state of the occluded object by applying Lagrange’s polynomial extrapolation using the apriori knowledge. Findings: The proposed method is evaluated using several challenging sequences of the benchmark IEEE PETS, IEEE CHANGE DETECTION, and EPFL dataset. Further, comparative evaluation with contemporary methods has been carried out to corroborate the efficacy of the proposed method. Application/Improvements: This work focuses on devising a new method to track multiple moving objects using color moments and Lagrange’s extrapolation framework which works for a complex environment and in the presence of occlusions. Further, the shadow elimination task after the motion segmentation could be considered as an improvement step in this work which will aid in better tracking results.
Relationship between personality traits and prognosis of posttraumatic stress disorder in flood survivors

Objective:To explore the prognosis of posttraumatic stress disorder (PTSD) in flood survivors 13 years after they had been diagnosed with PTSD symptoms,and investigate the relationship between their personality traits and the prognosis of PTSD.Method:In this cross-sectional study,the survivors of Dongting Lake flood in 1998-1999 in Hunan in China,who were investigated and screened as PTSD symptoms positive in 2000 were selected as the target population,from which a sample of 200subjects was drawn using amulti-stage random sampling method.The Posttraumatic Stress Disorder Scale Civilian Version (PCL-C) was used to examine and re-screen the participants of PTSD symptoms in order to explore the prognosis of PTSD.Participants whose PCL-C scores were equal to 44 or higher were classified as the PTSD symptoms positive group,while those with PCL-C scores less than 44 were classified as the recovered group.Personality traits were then assessed,using the Revised Eysenck Personality Questionnaire Short Scale for Chinese (EPQ-RSC),in both the recovered group and the PTSD symptoms positive group.Finally,the multivariate logistic regression analysis was used to investigate the relationship between the prognosis of PTSD and personality traits.Results:Totally 200 subjects were eligible for this study and completed the questionnaires,but 16 of them had their questionnaires excluded from data analysis because they provided incomplete information.Thus,the response rate was 92.0％. According to the PCL-C's cut-off score,22 participants were still screened as PTSD symptoms positive and were classified as the PTSD symptoms positive group,whereas the other 162 participants were screened as PTSD symptoms negative and were classified as the recovered group.Compared with the recovered group,the EPQ-RSC extroversion scores for the PTSD symptoms positive group were significantly lower [(51.8 ± 10.7) vs.(45.1 ± 13.2),P ＜ 0.05] and their neuroticism scores were significantly higher [(46.5 ± 10.1) vs.(58.3 ± 12.2),P ＜ 0.05]. The multivariate logistic regression analysis showed,after adjusting for the variables such as gender and age,that higher neuroticism (OR ＝ 3.63,95％ CI:1.05 -12.54) was a risk factor for the persistent PTSD symptoms in the flood survivors.Conclusions:It suggests that neuroticism is associated with prognosis of PTSD in flood survivors,those with higher neuroticism scores appear to have problems to recover from PTSD.
A New Steganographic Method using Word Length

Steganography is the technique of masking a message inside an innocuous media object without creating hunch to others. In this paper, we present a new approach to text steganography. The approach uses length of the words to conceal a secret message inside a text file. The resulting stego file is exactly the same as the cover file. We also present an empirical comparison of the proposed approach with some of the existing approaches and show that our approach yields better results.
Using Linked Open Data to Enrich a Corporate Memory of Universities

In this work we describe a proposal for managing educational resources produced by three high level educational institutions. Our approach takes into account not only the meta informations inside educational resources but also the meta informations extracted from linked open data in the web associated to massive open online courses (MOOCs). We visualize educational resources as a semantic corporate memory where semantic technologies and Linked Open Data approaches can improve the information integration. Textmining takes an important part in our approach for generating links between concepts and detecting some important associations.
The Hybrid Strategy Processing Approach of Complex Long Sentence

The processing of complex long sentences is a difficult problem in the implementation of a practical machine translation system.In this paper,a processing approach to the complex long sentence based on multi strategy is proposed,in which the rule based analysis and case based consistent matching are combined by using various linguistic features,including sentence length,punctuation,functional words and contextual condition and so on,which is used to segment the complex sentence into several simple sentences and to compose the translation text of these simple sentences together.In addition,by designing the uniform formalism of the knowledge representation,it is possible for this approach to be suitable to multi lingual translation system.
PREVALENCE AND CHARACTERISTICS ASSOCIATED WITH ALCOHOL USE AND ALCOHOL RELATED PROBLEMS IN COMMUNITY DWELLING OLDER ADULTS

Objective: This study examine the prevalence, characteristics and associated factors of alcohol use and alcohol related problems among Belgian community dwelling older adults. Design: Retrospective cross-sectional study by extensive examination survey. Setting: The participants were questioned in their homes or in community centres. Participants: Overall, 1,366 adults ≥65 years participated in this study. Method: Information about self-reported alcohol use during the past year, Health Related Quality of Life (HRQL) and alcohol related problems was gathered with respectively the AUDIT, SF36 and MAST-G. Results: Of the total sample, 84.4% reported alcohol consumption. Using the NIAAA guidelines, the overall prevalence for at risk drinking was 26.6% and for binge drinking 14.8%, both risky alcohol patterns. Logistic regression analyses were performed on the drinking sample to determine the predictors associated with at risk drinking, binge drinking and hazardous drinking. Being male, a smoker of former smoker and living alone were associated with at risk drinking. Being male, being aged 65-74 years, being a smoker, reporting polypharmacy, MCS and having recent loss experience were associated with binge drinking. More than 25% of respondents were classified as hazardous drinking (score ≥5 on MAST-G). Associated factors with hazardous drinking were being male, having a family history of alcohol problems, PCS and MCS. Conclusions: The prevalence rates for at risk alcohol patterns and alcohol related problems were higher than in previous studies. As older adults are more vulnerable to the adverse consequences of alcohol use, awareness about alcohol use should be raised among older adults, as well as amongst health care givers and researchers.
High Sugar-Fat Diet Induces Metabolic-Inflammatory Disorders Independent of Obesity Development

Background: The modern dietary habit, which is rich in refined carbohydrates and saturated fats, increases the risk of chronic diseases due to the proinflammatory effect of these nutrients. Aim: To evaluate the impact of high sugar-fat diet in the development of metabolic-inflammatory disorders in non-obese animals. Methods: Male Wistar rats were distributed into two groups according to the diet: control and high sugar-fat for 30 weeks. It was analyzed: dietary efficiency; chow, water and caloric intake; metabolic and hormonal profile in plasma and inflammatory cytokines in epididymal adipose tissue. Data were compared by Student’s t test or by Mann-Whitney U test with p < 0.05 as significant. Results: HSF presented lower chow intake, higher water consumption and dietary efficiency with no difference in the caloric intake. The final body weight (FBW) and weight gain (WG) were lower in the HSF group and there was no difference in the adiposity index (AI). HSF diet-induced hyperglycemia and hyperinsulinemia with no difference for Homeostatic Model Assessment for Insulin Resistance (HOMA-IR). Triglycerides, uric acid, adiponectin and leptin levels were higher in the HSF group. The HSF group showed increased interleukin-6 (IL-6) and tumoral necrosis factor-alpha (TNF-α) levels in epidydimal adipose tissue. The urinary protein-creatinine ratio and albuminuria were higher in the HSF group. Conclusion: HSF diet intake is directly involved in the development of metabolic-inflammatory disorders independent of obesity, dissociating the view that increased adiposity is the major risk factor for complications commonly found in obese individuals.
Binaural Sound Localization Based on Detection of Multi-band Zero-crossing Points

A method of binaural sound localization based on detection of multi-band zero-crossing points generated from binaural filter-band outputs is presented.To estimate ITD,conventional methods use cross-correlation of left and right instantaneous firing rates of neurons.However,these methods require high computational complexity involved in the computation of cross-correlation.Furthermore,they suffer from inaccuracies in estimating ITD in noisy multisource environments. In the suggested method,the ITD values are estimated by a histogram weighted by the estimated SNR computed from the variances of ITD samples.As a result,the method provides an accurate estimate of sound source direction and is more robust to noise.To verify the validity of the method,simulations for sound localization are performed under noise condition.The simulation results show that the method is able to provide an accurate estimate of sound source direction and is more robust to noise while offering significantly less com putational complexity compared to the conventional crosscorrelation based methods.
The development of a novel patient reported outcome measure for the assessment of the signs, symptoms and impact of underactive bladder

ii Acknowledgements.iii Author’s declaration.iv Table of contents.v List of tables.x List of Figures.xii List of publications. xiii Funding and outsourcing.xiv 1. Table of
Restoring ancestral phenotypes by reduction of plasticity is a general pattern in gene expression during adaptation to different stressors in Tribolium castaneum

Plasticity and evolution are two processes individuals to respond to environmental change, but how both are related and impact each other is still controversial. We studied plastic and evolutionary responses in gene expression of Tribolium castaneum after exposure to new environments that differed from ancestral conditions in temperature, humidity or both. Using experimental evolution with ten replicated lines per condition, we were able to demonstrate adaptation after 20 generations. We measured gene expression in each condition in adapted selection lines and control lines to infer evolutionary and plastic changes. We found more evidence for changes in mean expression (shift in the intercept of reaction norms) in adapted lines than for changes in plasticity (shifts in slopes). Plasticity was mainly preserved and was responsible for a large part of the phenotypic divergence in expression between ancestral and new conditions. However, we found that genes with the largest evolutionary changes in expression also evolved reduced plasticity and often showed expression levels closer to the ancestral stage. Results obtained in the three different conditions were similar suggesting that restoration of ancestral expression levels during adaptation is a general evolutionary pattern. We increased the sample size in the most stressful condition and were then able to detect a positive correlation between proportion of genes with reversion of the ancestral plastic response and mean fitness per selection line.
Acute Respiratory Health in Students Attending Middle Schools Near Concentrated Animal Feeding Operations

Conducting a research study provides an opportunity for meaningful interaction between researchers and participants. Epidemiologists should endeavor to incorporate positive side effects into studies with primary data collection. The Rural Air Pollutants and Children’s Health (RAPCH) study illustrates this philosophy. RAPCH was designed in collaboration with a community-based organization to provide educational and environmental health benefits to middle school participants and their communities while collecting epidemiologic data. The study was conducted with 340 students at three middle schools in February-November 2009. In May-June 2010, we interviewed principals, teachers, and research team members about perceived benefits and drawbacks of participating in the study. Qualitative analysis of interview transcripts revealed few drawbacks and many benefits. Positive impacts on students included increased interest in science and research, hands-on learning opportunities, exposure to new technology, reinforcement of science curricula, and contact with higher education. Teachers received exposure to research and additional resources for classroom lessons. The school liaisons described enhanced interest in research and increased environmental health awareness. Given the success of this effort, more epidemiologic research should be designed and conducted with immediate public health benefits in mind.
Rheumatic “Taussig-Bing Heart”: A Case Report

Aim: To report a case of acyanotic Taussig-Bing heart, anatomically consistent with L-transposition and rheumatic Left AV valve regurgitation associated with complete AV block in an adolescent male. Introduction: Taussig-Bing heart is one of the conotruncal malformation, characterized by double-outlet right ventricle (DORV) and a subpulmonary VSD. Embryologically, abnormal cardiac looping with malalignment of conotruncal septum result its complexity and great artery relationships. Case Report: A 14-year old acyanotic boy presented with severe left-sided AV valve regurgitation and bradycardia. ECG revealed left sided morphologic right ventricular hypertrophy (RVH) as evidenced by a loss of septal Q waves in left precordial leads suggesting ventricular inversion. X-ray chest revealed a straight upper right cardiac border due to loss of normal relationship of great vessels and cardiomegaly due to both left atrial and morphologic right ventricular enlargements suggesting a left-sided regurgitant lesion. Echocardiography revealed the ventricular inversion, primary origin of both L-transposed great arteries from the left-sided morphologic right ventricle suggesting a “double-outlet morphologic right ventricle” with “double discordance” and a subpulmonary VSD of Taussig-Bing type. The left-sided morphologic tricuspid valve is severely regurgitant due to rheumatic process resulting in heart failure which was improved with anti-failure measures and penicillin prophylaxis. Conclusion: The presence of left-sided regurgitation associated with bradycardia is a suspicion of “double discordance” and “double switch” procedure remains the mainstay of its surgical correction. Left AV valve replacement with intraventricular repair is preferred in this child since the malformation is consistent with Taussing-Bing type of DORV with L-transposition.
Synergetic action of ceria nanoparticles and doxorubicin on the early development of two fish species, Danio rerio and Puntius tetrazona

E. Yu. Krysanov, T. B. Demidova, O. S. Ivanova, K. G. Ordzhonikidze, A. B. Shcherbakov, V. K. Ivanov Severtsov Institute of Ecology and Evolution, Russian Academy of Sciences, Moscow, 119071 Russia Kurnakov Institute of General and Inorganic Chemistry, Russian Academy of Sciences, Moscow, 119991 Russia Vavilov Institute of General Genetics, Russian Academy of Sciences, Moscow, 119991 Russia Zabolotny Institute of Microbiology and Virology,NAS of Ukraine, Kiev, D 03680 Ukraine National Research Tomsk State University, Tomsk, 634050 Russia
Does resistance training reduce low back pain

OBJECTIVE: The objective of this selective EBM review is to determine whether or not resistance training reduces low back pain. STUDY DESIGN: Review of three English language primary studies published in 2011, 2014, and 2015. DATA SOURCES: Randomized controlled and clinical trials comparing resistance training (kettlebell training, graded activity, TOTRX, LEXT) to physiotherapy exercise and no exercise intervention, found using PubMed. OUTCOME MEASURED: Severity of pain in the low-back area, measured using Pain Numerical Rating Scale (NRSpain) and pain visual-analog scale. RESULTS: Two out of three studies found that resistance training reduced low back pain in comparison to a control group without an exercise intervention. One RCT found that resistance training/graded activity had the same effects of reducing low back pain as physiotherapy exercises. CONCLUSIONS: The result of the RCT and clinical trials demonstrated that resistance training reduces low back pain in comparison to no intervention. Resistance training compared to other forms of exercise intervention, specifically physiotherapy, is equally as effective in reducing low back pain.
Monte Carlo localization algorithm for mobile node by reducing sampled area

In response to the problem of mobile node position for WSN, an improved MCL algorithm for mobile unknown node and fixed beacon node is proposed. Sampled area is reduced to improve the sampling efficiency by using the ranging error of beacon node and unknown node sufficiently. The simulation results show that the improved algorithm can improve the localization accuracy, reduce the number of sampling and computation, and prolong the network life cycle in different conditions of the beacon node density, connectivity and the maximum velocity of node.
Analysis of Effect of Flooding on Performance of Ad hoc Network

Mobile Ad hoc networks (MANET) are a new paradigm of networks offering unrestricted mobility without any underlying infrastructure. The network is set up with a group of mobile wireless nodes and is devoid of any dedicated routers or base stations. The wireless nodes move around freely and mutually cooperate with each other in routing and forwarding packets without the support of any fixed infrastructure or centralized administration. The topology is highly dynamic, making the routing procedure more difficult and insecure. In this paper, the performance of the network is analyzed after flooding the network using malicious nodes. The flooding attack is done by the malicious node by sending fake RREQ packets throughout the network. The number of malicious nodes and their position is changed along with various other node characteristics to observe their respective effects on the network performance. The simulation environment is implemented by using the NS-3 network simulator.