Miracle-dz/UniFAR-FTUs huggingface dataset:
Defending the digital: Awareness of digital selectivity in historical research practice

Existing research offers fearful conclusions on the use of online archival collections, finding that historians ignore and overlook the limitations of digital sources. However, an attitudinal case study at Newcastle University contradicts this consensus. This article discusses this study’s detailed findings, determining that historians and library professionals demonstrate abundant and nuanced awareness of issues relating to ‘digital selectivity’. Nevertheless, the interviewees suggested that this does not radically undermine their practice. The study also revealed compelling aspects of digital selectivity not currently observed in existing research, including the effects of career stage and the importance of cooperation with library professionals. While the existing literature provides appropriate and prudent concerns, it lacks tangible evidence pointing to a widespread phenomenon of poor digital historical practice. The article closes by recommending further research into historians’ digital information-seeking behaviour, but argues that standardized metadata practices must come first. Limitations, including the absence of rigorous quantitative data, must be resolved before a fuller appreciation for digital historical practice is developed.
Generation of Continuously Variable-mode Orbital Angular Momentum Beams

Orbital angular momentum (OAM) beam emitters with compact structure and high performance are highly desirable for wireless communication and radar technology. Here, we propose a compact emitter that only consists of a ring resonator and a feed line. Continuously ‐ variable ‐ mode OAM beams are generated by adjusting the wavelength and transmission path. The basic design principle and specific evaluation index are discussed. Both the simulated and experimental results demonstrate that the proposed emitter obtains the capacity of generating variable ‐ modes. This approach opens a way for designing novel OAM beam emitter with desired properties.
Guizhi Fuling Capsule Exhibits Antidysmenorrhea Activity by Inhibition of Cyclooxygenase Activity

Guizhi Fuling capsule (GZFLc) is a modern preparation from traditional Chinese Medicine. Guizhi Fuling was first prescribed by Zhang Zhongjing almost two thousand years ago for the treatment of primary dysmenorrhea. It has also been used to treat uterine fibroids, dysfunctional uterine bleeding, and endometriosis. Although effective against dysmenorrhea clinically, there are limited information on the mechanism of its action. The major components responsible for the activity are not well defined. The aim of this study has been to elucidate a mechanism that may facilitate the development of a bioactivity-based assay for quality control during drug formulation and manufacturing. Using an oxytocin-induced mouse dysmenorrhea model, we showed that oral administration of GZFLc at 150 and 300 mg/kg, dosages relevant to clinic usages, significantly suppressed oxytocin-induced writhing response. The antidysmenorrhea effect was also demonstrated by a rotarod assay. We showed that GZFLc treatment significantly prolonged the hanging time of mice on the rotating rod. Histological studies showed that GZFLc treatment reduced lamina propria edema, while no effect on COX2 expression was detected. GZFLc instead exhibited direct inhibitory effect against COX2, a critical enzyme that catalyzes arachidonic acid conversion to prostaglandins. By HPLC profiling, we showed that paeoniflorin, paeonol, and cinnamaldehyde are the major components from the corresponding plants. At 5 and 10 mg/kg, both paeoniflorin and paeonol were active against induced dysmenorrhea. The study not only links GZFLc antidysmenorrhea activity to COX2 inhibition but also uncovers a mechanism of action by which an assay can be developed for bioefficacy evaluation of GZFLc.
Ochratoxin- and aflatoxin-producing fungi associated with green and roasted coffee samples consumed in Argentina

The aims of this work were to identify the Aspergillus sections Nigri and Flavi, and to evaluate the natural occurrence of ochratoxin A (OTA) and aflatoxins in green and roasted coffee bean samples. The capacity to produce these toxins by Aspergillus species was also studied. Fifty samples of Colombian coffee beans (25 green and 25 roasted) were obtained from a processor plant located in the south of Cordoba province (Argentina). OTA and aflatoxin analysis were performed by high performance liquid chromatography (HPLC). OTA production by strains belonging to Aspergillus niger aggregate were cultivated using YES medium and detected by HPLC. Aflatoxin production was tested in strains belonging to section Flavi on malt extract agar and was detected by thin liquid chromatography (TLC). From green coffee samples, the predominant species isolated belonged to A. niger aggregate, 60 and 55%, in dichloran rose bengal chloramphenicol agar (DRBC) and dichloran 18% glycerol agar (DG18) respectively. While A. flavus s.
Efecto de cuatro ecotipos de Lepidium peruvianum Chacón sobre la producción de óxido nítrico in vitro

Los macrofagos desempenan un rol importante en la respuesta innata y adaptativa, durante su activacion producen mediadores citotoxicos como Oxido Nitrico (NO). El objetivo fue evaluar la produccion de NO por macrofagos peritoneales de raton cultivados con extractos metanolicos (EM) de los ecotipos rojo, negro, morado y blanco de Lepidium peruvianum Chacon (tambien conocida como Lepidium meyenii Walp). Los EM se prepararon empleando maca pulverizada macerada en metanol (1:2) durante 10 dias. Los macrofagos peritoneales se obtuvieron de ratones 3 dias despues de haberles inyectado 1 ml de Caldo Tioglicolato por via intraperitoneal; se cultivaron por triplicado durante 18 h a 37 °C en medio RPMI 1640 suplementado con 10% de suero de bovino fetal. La dosis de EM fue de 800 μg/ml por ecotipo, se consideraron controles sin EM. La produccion de NO se determino por acumulacion de nitrito en el medio y se evidencio con el reactivo de Peter Griess, las concentraciones de nitrito se calcularon en base a la curva estandar elaborada con NaNO2. Las concentraciones producidas de nitrito fueron de 7,45; 6,79; 5,76; 5,61 y 6,81 mM para los EM de los ecotipos morado, negro, blanco, rojo y control respectivamente. Los cuatro ecotipos indujeron la produccion de NO, aunque con el ecotipo morado fue superior (p>0,05).
Exploring Educator Values Alignment Strategies in an Intervention Context: The Emergence of the Beacon Strategy

Purpose: The purpose of this paper is to explore whether the four value alignment strategies available to educators (Scaffolding, Balancing, Intervention, and Refuge) previously identified in the mathematics education literature comprehensively capture educator value alignment strategies in an intervention context. Design/Approach/Methods: To this end, we analyse semi-structured interview data with two teacher-leaders involved in the Getting Ready in Numeracy (G.R.I.N.) intervention program through a value alignment lens. Findings: We ascertain that a fifth strategy, the Beacon strategy, is needed to describe the range of value alignment strategies employed by educators in the G.R. I.N. program. The Beacon strategy involves the educator digging in and reasserting their expectations until the student behaves in a manner that aligns with the educator’s values. In part it involves the educator being able to recognize their own values and clearly communicating these values to students. Originality/Value: This article further explores strategies that educators have at their disposal for aligning their values with those of their students. The uncovering of the Beacon strategy is particularly valuable as it suggests that educators could be purposefully pursuing value alignment even when they do not appear to take any active steps to move further towards their students’ sets of values.
The Genus Alistipes: Gut Bacteria With Emerging Implications to Inflammation, Cancer, and Mental Health

Alistipes is a relatively new genus of bacteria isolated primarily from medical clinical samples, although at a low rate compared to other genus members of the Bacteroidetes phylum, which are highly relevant in dysbiosis and disease. According to the taxonomy database at The National Center for Biotechnology Information, the genus consists of 13 species: Alistipes finegoldii, Alistipes putredinis, Alistipes onderdonkii, Alistipes shahii, Alistipes indistinctus, Alistipes senegalensis, Alistipes timonensis, Alistipes obesi, Alistipes ihumii, Alistipes inops, Alistipes megaguti, Alistipes provencensis, and Alistipes massiliensis. Alistipes communis and A. dispar, and the subspecies A. Onderdonkii subspecies vulgaris (vs. onderdonkii subsp.) are the newest strains featured outside that list. Although typically isolated from the human gut microbiome various species of this genus have been isolated from patients suffering from appendicitis, and abdominal and rectal abscess. It is possible that as Alistipes spp. emerge, their identification in clinical samples may be underrepresented as novel MS-TOF methods may not be fully capable to discriminate distinct species as separate since it will require the upgrading of MS-TOF identification databases. In terms of pathogenicity, there is contrasting evidence indicating that Alistipes may have protective effects against some diseases, including liver fibrosis, colitis, cancer immunotherapy, and cardiovascular disease. In contrast, other studies indicate Alistipes is pathogenic in colorectal cancer and is associated with mental signs of depression. Gut dysbiosis seems to play a role in determining the compositional abundance of Alistipes in the feces (e.g., in non-alcoholic steatohepatitis, hepatic encephalopathy, and liver fibrosis). Since Alistipes is a relatively recent sub-branch genus of the Bacteroidetes phylum, and since Bacteroidetes are commonly associated with chronic intestinal inflammation, this narrative review illustrates emerging immunological and mechanistic implications by which Alistipes spp. correlate with human health.
Challenges in UAS-Based TIR Imagery Processing: Image Alignment and Uncertainty Quantification

Thermal infrared measurements acquired with unmanned aerial systems (UAS) allow for high spatial resolution and flexibility in the time of image acquisition to assess ground surface temperature. Nevertheless, thermal infrared cameras mounted on UAS suffer from low radiometric accuracy as well as low image resolution and contrast hampering image alignment. Our analysis aims to determine the impact of the sun elevation angle (SEA), weather conditions, land cover, image contrast enhancement, geometric camera calibration, and inclusion of yaw angle information and generic and reference pre-selection methods on the point cloud and number of aligned images generated by Agisoft Metashape. We, therefore, use a total amount of 56 single data sets acquired on different days, times of day, weather conditions, and land cover types. Furthermore, we assess camera noise and the effect of temperature correction based on air temperature using features extracted by structure from motion. The study shows for the first time generalizable implications on thermal infrared image acquisitions and presents an approach to perform the analysis with a quality measure of inter-image sensor noise. Better image alignment is reached for conditions of high contrast such as clear weather conditions and high SEA. Alignment can be improved by applying a contrast enhancement and choosing both, reference and generic pre-selection. Grassland areas are best alignable, followed by cropland and forests. Geometric camera calibration hampers feature detection and matching. Temperature correction shows no effect on radiometric camera uncertainty. Based on a valid statistical analysis of the acquired data sets, we derive general suggestions for the planning of a successful field campaign as well as recommendations for a suitable preprocessing workflow.
Rhythm in Sora Trilingual Readers

This work investigates the rhythm of read speech as produced by Sora speakers in Assam. Sora is an Austro-Asiatic language and not much is known about the speech rhythm of these languages. Many of the Sora speakers in Assam are trilingual, as they speak Sora, Sadri and Assamese. While Assamese is the dominant language in the area, Sadri is a lingua-franca used by Sora speakers to communicate with speakers of other languages. In this work, we investigated the difference in rhythm when the speakers of Sora read Assamese, Sadri and Sora texts. Conventional rhythm measures, such as %V, nPVI, r-PVI, varco-V , varco-C, ∆ V and ∆ C are calculated for the read speech. The results showed that read Sora speech tends to be more mora-timed. However, when the same speakers read Assamese text, their rhythm properties are neither Assamese-like nor Sora-like. Similarly, the rhythm in the Sora speakers speaking Sadri also is very distinct and does not reﬂect any L1 inﬂuence.
Competitive strategies and international new ventures’ performance: Exploring the moderating effects of internationalization duration and preparation

The purpose of this article is twofold: to bring back to discussion the importance of strategy as a key element for international new ventures (INVs) to achieve higher international performance and to assess the relevance of contingency perspective, particularly two organizational contingency factors (internationalization duration and internationalization preparation), in moderating the strategy–performance relationship. The framework developed addresses the effects of four competitive strategies (cost leadership and innovation-based, marketing-based, and quality- and service-based differentiation) as determinants of INVs’ international performance. In addition, internationalization duration and internationalization preparation are included as moderators of these relationships. The hypotheses were tested using a sample of 319 INVs. The findings show that marketing and quality and service differentiation strategies are associated with higher INVs’ international performance and that internationalization duration and internationalization preparation play relevant moderating effects. JEL CLASSIFICATION: M13; M16
High-Level Production of γ-Linolenic Acid in Brassica juncea Using a Δ6 Desaturase from Pythium irregulare

γ-Linolenic acid (GLA), a nutritionally important fatty acid in mammals, is synthesized by a Δ6 desaturase. Here, we report identification of PiD6, a new cDNA from the oleaginous fungus, Pythium irregulare, encoding a 459-amino acid protein that shares sequence similarity to carboxyl-directed desaturases from various species. Expression ofPiD6 in yeast (Saccharomyces cerevisiae) revealed that it converts exogenously supplied linoleic acid into GLA, indicating that it encodes a Δ6 fatty acid desaturase. Expression of the desaturase in Brassica juncea under the control of the Brassica napus napin promoter resulted in production of three Δ6 unsaturated fatty acids (18:2–6, 9; 18:3–6, 9, 12; and 18:4–6, 9, 12, 15) in seeds. Among them, GLA (18:3–6, 9, 12) is the most abundant and accounts for up to 40% of the total seed fatty acids. Lipid class and positional analysis indicated that GLA is almost exclusively incorporated into triacylglycerol (98.5%) with only trace amounts found in the other lipids. Within triacylglycerols, GLA is more abundant at the sn-2 position.
Entrepreneurial universities and intermediary organizations as a success factor in SMEs: Literature review

Osnovni cilj ovog rada jeste da ukaže na ulogu koju preduzetnički univerziteti i posredničke organizacije imaju kao faktori uspešnosti malih i srednjih preduzeća. Preduzetnički univerziteti predstavljaju institucije koje preduzimaju preduzetničke aktivnosti s ciljem unapređenja regionalnih i nacionalnih ekonomskih pokazatelja. S druge strane, uloga posredničkih organizacija jeste unapređenje mogućnosti komercijalizacije nauke pružajući skup specijalizovanih usluga. U radu je istaknuta uloga i značaj tri osnovna tipa posredničkih organizacija, kao što su univerzitetski transfer tehnologije i postojanje kancelarija za licenciranje, fizičke intermedijarne organizacije (inkubatori, akceleratori i co-working prostor) i specifični izvori finansiranja novih poslovnih poduhvata (rizični kapital, investicioni anđeli i masovno finansiranje). Takođe, u radu je istaknuta uloga i značaj pomenutih posredničkih organizacija u Srbiji, sa namerom da se ukaže na njihov uticaj na formiranje novih malih i srednjih preduzeća. U radu istražujemo kako funkcionišu ovi različiti oblici posrednika i kako pružaju komplementarne i srodne usluge kao podršku naučnoj komercijalizaciji kroz preduzetništvo. Osnovna svrha pomenutih tipova organizacija jeste da služe kao faktori opstanka, rasta i razvoja malih i srednjih preduzeća.
Effects of geographic information system vector–raster–vector data conversion on landscape indices

The effects of geographic information system (GIS) data conversion on several polygon-and landscape-level indices were evaluated by using a GIS vegetation coverage from eastern Oregon, U.S.A. A vector–raster–vector conversion process was used to examine changes in GIS data. This process is widely used for data input (digital scanning of vector maps) and somewhat less widely used for data conversion (output of GIS data to specific formats). Most measures were sensitive to the grid cell size used in the conversion process. At the polygon level, using the conversion process with grid cell sizes of 3.05, 6.10, and 10 m produced relatively small changes to the original polygons in terms of ln(polygon area), ln(polygon perimeter), and 1/(fractal dimension). When grid cell size increased to 20 and 30 m, however, polygons were significantly different (p < 0.05) according to these polygon-level indices. At the landscape level, the number of polygons, polygon size coefficient of variation (CV), and edge density inc.
Simple Controlling Ecofriendly Synthesis of Silver Nanoparticles at Room Temperature Using Lemon Juice Extract and Commercial Rice Vinegar

Silver nanoparticles were prepared in an ecofriendly manner at room temperature via the stepwise-modified Tollens route using the lemon juice extract and commercial rice vinegar. In this work, the lemon juice extract—a natural-origin chemical—was used as a reducing and stabilizing agent, and commercial rice vinegar was used to create a low acidic environment to control the silver nanoparticle growth via the stepwise method. The average dimension of silver nanoparticles was qualitatively evaluated through the UV-Vis spectra via the Mie theory. The X-ray diffraction and field emission scanning electron spectroscopy were employed to study the purity, the crystal structure, and the morphology of samples, respectively. Due to the weak activity and low purity of ecofriendly chemicals, the reaction and baking times strongly affect the preparation efficiency in obtaining small-size silver nanoparticles (∼40 nm). The highest efficiency was obtained with 24 h reaction time and 48 h baking time. The bimodal distribution of the size of silver nanoparticles was observed by UV-Vis analysis and field emission scanning electron microscopy. The obtained small-size silver nanoparticles (∼40 nm) have a uniform dimension. The quality of the obtained silver nanoparticles was evaluated through the conducting properties of silver paint made from ecosynthesized silver nanoparticles which showed a promising prospect to develop green-synthesized silver paint working at room temperature.
Effect of the DC-Link Capacitor Size on the Wireless Inductive-Coupled Opportunity-Charging of a Drone Battery

Wireless inductive-coupled power transfer and opportunity battery charging are very appealing techniques in drone applications. Weight and size are very critical constraints in drones, so the battery and the on-board electronics must be as light and small as possible. The on-board components involved in the resonant inductive-coupled wireless power transfer usually consist of the secondary coil, the compensation capacitor, the bridge rectifier, the LC-filter and the battery. This paper suggests a sizing of the LC-filter capacitor that improves the charging power of the battery. In addition, further on-board space and size is saved by using the stray inductance of the battery as filtering inductor. LTSpice simulations and experimental tests carried out on the prototype of a wireless power transfer circuit shows the dependency of the power delivered to the battery on the filter capacitor size. Finally, it is found that the power transfer to the battery is maximized by choosing the capacitor value that sets the LC-filter resonant frequency close to the double of the excitation frequency of the wireless charging. The drawback is a large current and voltage ripple in the battery.
Predicting Very Severe Kawasaki Disease Who Does Not Respond to Initial Steroid Combination Therapy: A Prospective Cohort Study

Objective: Kawasaki Disease (KD) is an acute systemic vasculitis that can lead to ischemic heart disease resulting from coronary artery aneurysms. Intravenous Immunoglobulin (IVIG) resistance is a major risk factor for the development of Coronary Artery Lesions (CALs). Pulsed or non-pulsed steroids combination therapy as initial treatment for children with high risk KD was listed in the Japanese guideline in 2012. However, some patients with very severe KD do not improve even with the steroid combination therapy. The purpose of this study was to clarify the risk factors for severe KD patients who do not respond to the steroid combination therapy, and to confirm whether they can be predicted in the early stage. Methods: Forty hospitalized KD patients with high scores on all three Japanese prediction scoring systems and who received steroids with IVIG in initial treatment were prospectively recruited. IVIG+steroid-responder group (n=21) required no additional therapy and IVIG+steroid-resistance group (n=19) required additional therapy. Clinical data before and after the initial treatment were compared between each group. Results: Kobayashi and Egami scores before the initial treatment and the neutrophil count 2 days after the initial treatment were higher in IVIG+steroid-resistance group than that in IVIG+steroid-responder group independently. Kobayashi score ≥ 7, 2 points; Egami score ≥ 4, 1 point; and neutrophil count after initial treatment ≥ 11000/μL, 2 points. Patients who had three points or more were likely to need additional treatment (sensitivity 89%, specificity 76%). Conclusions: Predicting very severe KD who does not respond to the steroid combination therapy in the early stage is possible. Our new, original model may help to predict non-responders to the initial steroid combination therapy and prevent coronary artery aneurysms.