Miracle-dz/UniFAR-FTUs huggingface dataset:
Factor Analyses and Validity of the Transplant Evaluation Rating Scale (TERS) in a Large Sample of Lung Transplant Candidates

Objective It is well known that the occurrence of mental disorders is more common in lung transplant candidates compared to the general population. After transplantation mental disorders may negatively affect quality of life, adherence to immunosuppressive medication, as well as overall survival. Therefore, the identification of patients at risk is of utmost importance and in Germany pre-transplant psychosocial evaluation of the patients is required. To ensure high quality and comparability of these assessments, the use of psychometrically sound instruments is recommended. We applied the Transplant Evaluation Rating Scale (TERS), a broadly used expert interview. Two research groups have detected a two-factor structure of the TERS in different transplant samples; however, with slightly different results. The present study investigated which of the models would fit best in our sample of lung transplant patients. Additionally, we assessed convergent and predictive validity of the best fitting model to evaluate its clinical usefulness. Methods Between 2016 and 2019, 390 lung transplant candidates were evaluated and included in the study. The median age was 53 years and 54% were male. TERS interviews were conducted by trained medical doctors and psychologists. The participants completed questionnaires assessing quality of life and levels of depression and anxiety. Transplant- and disease-specific variables (lung disease, listing date, oxygen use) were taken from the patient charts. Confirmatory factor analysis was used to test the two proposed TERS-models in the present sample. Results The two-factor structure of the TERS reported by Hoodin and Kalbfleisch fit our sample best, showing good psychometric properties. The factor “emotional sensitivity” was highly correlated with quality of life and measures of psychosocial health while the factor “defiance” correlated with obstructive lung disease and older age but not with quality of life. The two factors showed differential predictive validity with regard to time until listing and pulmonary-specific quality of life 1 year after transplantation. Conclusions The two factors showed good psychometric properties, and differential convergent and predictive validity. However, further studies concentrating on the predictive value of the TERS and its factors regarding somatic outcomes (mortality, graft functioning) are required.
Effects of in Season Multi-Directional Plyometric Training on Vertical Jump Performance, Change of Direction Speed and Dynamic Postural Control in U-21 Soccer Players

The aim of the study was to assess the effects of multi-directional plyometric training (MPT) on vertical jump height, change of direction speed (CODS), and dynamic postural control (DPC) of soccer players under 21 year (U-21). Twenty-seven male soccer players were randomly allocated to either an experimental group (EG; n = 14; age: 19.0 ± 0.9 years) or a control group (CG; n = 13; age: 19.0 ± 0.7 years). The EG introduced 6 weeks MPT, 2 days per week into their in-season training, while CG continued training without change. Measurements of vertical jump height, CODS and DPC were completed at the beginning and end of the 6 week MPT. ANOVA demonstrated a significant group × time interaction for SJ (F = 6.03, p = 0.021), CMJ (F = 9.10, p = 0.006), and T-Test (F = 10.46, p = 0.002). The Bonferroni Post Hoc test demonstrated significant increase for the three tests in both group (EG and CG). For SJ (EG: p < 0.001; CG: p < 0.001), CMJ (EG: p < 0.001; CG: p = 0.005) and T-Test (EG: p < 0.001; CG: p = 0.02). For DPC on the dominant leg, there was a significant group × time interaction for four axes [anterior (F = 5.48, p = 0.028), antero-lateral (F = 4.82, p = 0.038), postero-lateral (F = 4.82, p = 0.038), and medial (F = 6.77, p = 0.015)]. The Bonferroni Post Hoc test demonstrated significant increase in EG (p < 0.001), but no significant change in CG in four axes (anterior, antero-lateral, postero-lateral and medial). Furthermore DPC on the non-dominant leg, there was a significant group × time interaction for three axes [lateral (F = 8.09, p = 0.009), postero-lateral (F = 11.92, p = 0.002), and medial (F = 5.84, p = 0.023)]. The Bonferroni Post Hoc test demonstrated significant increase in EG (p < 0.001), but no significant change in CG in three axes (lateral, postero-lateral, and medial). In conclusion, incorporating MPT into the in-season regimen of under 21 soccer players improved performance of various indices related to soccer activity (i.e., CMJ, CODS, and DPC). MPT has the potential to be appealing to coaches, as it requires little time while yielding valuable results in the physical preparation of soccer players.
The Sequencing of Game Complexes in Women’s Volleyball

In volleyball, each team must use no more than three hits to return the ball to the opponent’s court. This unique aspect of volleyball means that playing actions can be grouped into different complexes, mainly based on the initial defensive action. The purpose of this study was to find out which game complexes are most common in women’s volleyball and how those phases are sequenced. The study analyzed 4,252 complexes from 1,176 rallies or points (seven matches, with 27 sets in total) in the 2015 and 2016 Copa de la Reina. The variables analyzed were the game complex, complex efficacy, and number of complexes per point. Two Markov chains were defined to visualize how the complexes are sequenced. The first chain looked only at categories of the game complex variable, taking seven states and 24 transitions into consideration. The second chain combined the game complex and complex efficacy variables, taking 26 states and 125 transitions into consideration. These chains provide practical information regarding which sequences of complexes occur most frequently in the competition analyzed, and therefore which ones should be the main focus in training sessions. The most frequent sequence was Complex 0 (the serve), followed by Complex I with in-system attack, followed by Complex II without continuity.
A Comparison of Divergent Thinking Abilities Between Healthy Elderly Subjects and MCI Patients: Preliminary Findings and Implications

Objective Divergent thinking (DT) has attracted research interest because of its potential role in early diagnosis and rehabilitation programs for patients affected by neurodegenerative diseases. Recently, DT has received even more attention because of its proven relationship with cognitive reserve (CR) and the possibility of a standardized assessment. However, few studies have investigated this ability in dementia patients, and even less is known about patients affected by Mild Cognitive Impairment (MCI). Thus, this study aims to investigate DT abilities in MCI patients. Methods A total of 25 MCI patients and 25 healthy controls subjects (HC; from a random selection of 50) matched for age, gender, and educational level were enrolled. General cognitive functioning was measured by the Montreal Cognitive Assessment (MoCA), while the Abbreviated Torrance Test for Adults (ATTA) was selected to measure DT. Results MANOVA analysis did not reveal any significant differences in DT abilities between MCI patients and HC except for the figural indicator score. A logistic hierarchical regression analysis revealed that the figural indicator score added an 8% of accuracy in the prediction of the group variable over the general cognition measure (MoCA). Conclusion MCI patients seem to perform significantly worse than HC only in the figural DT score and this evidence has significant practical implications. First, that figural DT seemed to decrease even earlier than verbal DT and could therefore be taken into account for early diagnosis of MCI patients. On the contrary, the sparing of all the other DT skills (such as verbal DT skills, fluency, flexibility, originality, and elaboration) may suggest that, given its relationship with CR, verbal DT could instead be considered a possible target for prevention or early cognitive stimulation interventions.
Spinal Mobilization Prevents NGF-Induced Trunk Mechanical Hyperalgesia and Attenuates Expression of CGRP

Introduction Low back pain (LBP) is a complex and growing global health problem in need of more effective pain management strategies. Spinal mobilization (SM) is a non-pharmacological approach recommended by most clinical guidelines for LBP, but greater utilization and treatment optimization are hampered by a lack of mechanistic knowledge underlying its hypoalgesic clinical effects. Methods Groups of female Sprague-Dawley rats received unilateral trunk (L5 vertebral level) injections (50 μl) of either vehicle (phosphate-buffer solution, PBS; VEH) or nerve growth factor (NGF; 0.8 μM) on Days 0 and 5 with or without daily L5 SM (VEH, NGF, VEH + SM, VEH + SM). Daily passive SM (10 min) was delivered by a feedback motor (1.2 Hz, 0.9N) from Days 1 to 12. Changes in pain assays were determined for mechanical and thermal reflexive behavior, exploratory behavior (open field events) and spontaneous pain behavior (rat grimace scale). On Day 12, lumbar (L1–L6) dorsal root ganglia (DRG) were harvested bilaterally and calcitonin gene-related peptide (CGRP) positive immunoreactive neurons were quantified from 3 animals (1 DRG tissue section per segmental level) per experimental group. Results NGF induced bilateral trunk (left P = 0.006, right P = 0.001) mechanical hyperalgesia and unilateral hindpaw allodynia (P = 0.006) compared to the vehicle group by Day 12. Additionally, we found for the first time that NGF animals demonstrated decreased exploratory behaviors (total distance traveled) and increased grimace scale scoring compared to the VEH group. Passive SM prevented this development of local (trunk) mechanical hyperalgesia and distant (hindpaw) allodynia, and normalized grimace scale scores. NGF increased CGRP positive immunoreactive neurons in ipsilateral lumbar DRGs compared to the VEH group ([L1]P = 0.02; [L2]P = 0.007) and SM effectively negated this increase in pain-related neuropeptide CGRP expression. Conclusion SM prevents the development of local (trunk) NGF-induced mechanical hyperalgesia and distant (hindpaw) allodynia, in part, through attenuation of CGRP expression in lumbar DRG sensory neurons. NGF decreases rat exploratory behavior and increases spontaneous pain for which passive SM acts to mitigate these pain-related behavioral changes. These initial study findings suggest that beginning daily SM soon after injury onset might act to minimize or prevent the development of LBP by reducing production of pain-related neuropeptides.
Isochlorogenic Acid A Attenuates the Progression of Liver Fibrosis Through Regulating HMGB1/TLR4/NF-κB Signaling Pathway

Liver fibrosis, a chronic damage process related to further progression of hepatic cirrhosis, has yet no truly effective treatment. Isochlorogenic acid A (ICQA), isolated from a traditional Chinese herbal medicine named Laggera alata (DC.) Sch.Bip. ex Oliv. (Asteraceae), is proved to exhibit anti-inflammatory, hepatoprotective and antiviral properties. However, the actions of ICQA on liver fibrosis are poorly understood. The purpose of this study was to evaluate the actions of ICQA on liver fibrosis and clarify the underlying mechanism. It was found that ICQA had significant protective actions on liver injury, inflammation as we as fibrosis in rats. Meanwhile, ICQA prevented hepatic stellate cells (HSC) activation, indicated by its inhibitory effect on the overexpression of α-smooth muscle actin (α-SMA). In addition, the reduced fibrosis was found to be associated with the decreased protein expression of high-mobility group box 1 (HMGB1) as well as toll like receptor (TLR) 4. Simultaneously, ICQA can suppress the cytoplasmic translocation of HMGB1 in rat liver. Further investigations indicated that ICQA treatment dramatically attenuated the nuclear translocation of the nuclear factor-kB (NF-κB) p65 and suppressed the hepatic expression of p−IκBα in rats with liver fibrosis. Taken together, our study indicated that ICQA could protect against CCl4-induced liver fibrosis probably through suppressing the HMGB1/TLR4/NF-κB signaling pathways.
The structure of cells in tissues as revealed by microdissection. II. The physical properties of the living axis cylinder in the myelinated nerve fiber of the frog

The question of the structure of the myelinated nerve fibers has been the subject of much discussion. The publications on this subject are numei-ous. lTnfortunately, we can find but few among them dealing with observations on living nerve fibers, and these few have not been sufficiently recognized. The authors of text-books and encyclopedias have accepted the results of investigators who used the results of complicated histological methods, instead of the few who have studied the living nerve fibers. This is true not because fixed and stained preparations give results of greater value or more accuracy, but because the former are so very numerous and have been contributed by investigators of such indubitable reliability. Although so much work has been done w-ith the commonly used fixed and stained preparations, the results are far from satisfactory. To the superficial observer it might seem that the structure of the nerve fiber is known in all its details. However, a thorough study of the literature arouses some doubts in one’s mind, because these detailed descriptions very often contradict one another. In the literature there are descriptions, no doubt, which cover the reality, but, considering the fact that a great variety of methods has
Automatic individual holstein friesian cattle identification via selective local coat pattern matching in RGB-D imagery

The objective of this paper is the fully automated visual identification of individual Holstein Friesian cattle from dorsal RGB-D imagery taken in real-world farm environments. Autonomous and non-intrusive cattle identification could provide an essential tool for economically-viable machinised farming analytics, social monitoring, cattle traceability, food production management and more. We contribute a dataset and propose a system that can reliably derive animal identities from top-down stills by first depth-segmenting animals in RGB-D frames, and then extracting a subset of local ASIFT coat descriptors predicted as sufficiently individually distinctive across the species. Predictions are generated by a support vector machine (SVM) using radial basis function (RBF) kernels for predictions based on the ASIFT descriptor structure. We show that learning such a species-specific ID-model is effective, and we demonstrate robustness to poor or complex input image conditions such as more than one cow present, bad depth segmentation, etc. The proposed system yields 97% identification accuracy over testing on approximately 86,000 image pair comparisons covering a herd of 40 individuals from the FriesianCattle2015 Dataset.
The Lepidoptera (INSECTA) Fauna of Düzce Province, Turkey

The lepidopteran species of Duzce province were investigated. To collect specimens, a sweep net and light traps were used. A total of 109 species belonging to 17 families of the order Lepidoptera were identified. The family Geometridae was represented by the highest number of species (20), followed by Noctuidae (19), Lycaenidae (12) and Nymphalidae (12). This was the first study to determine the Lepidoptera fauna of Duzce.
Novel pattern recognition approaches for transcriptomics data analysis

We proposed a family of methods for transcriptomics and geno mics data analysis based on multi-level thresholding approach, such as OMTG for subgrid and spot detection in DNA microarrays, and OMT for detecting significant regions b ased on next generation sequencing data. Extensive experiments on real-life datas ets and a comparison to other methods show that the proposed methods perform these tasks f ully automatically and with a very high degree of accuracy. Moreover, unlike previous met hods, the proposed approaches can be used in various types of transcriptome analysis probl ems such as microarray image gridding with different resolutions and spot sizes as well a s finding the interacting regions of DNA with a protein of interest using ChIP-Seq data without any need for parameter adjustment. We also developed constrained multi-level thr s olding (CMT), an algorithm used to detect enriched regions on ChIP-Seq data with the abi lity of targeting regions within a specific range. We show that CMT has higher accuracy in detec ting enriched regions (peaks) by objectively assessing its performance relative to other previously proposed peak finders. This is shown by testing three algorithms on the well -known FoxA1 Data set, four transcription factors (with a total of six antibodies) for D osophila melanogaster and the H3K4ac antibody dataset. Finally, we propose a tree-based a ppro ch that conducts gene selection and builds a classifier simultaneously, in order t o select the minimal number of genes that would reliably predict a given breast cancer subt ype. Our results support that this
PENERAPAN METODE ANOVA UNTUK ANALISIS SIFAT MEKANIK KOMPOSIT SERABUT KELAPA

Anova test is a form of statistical hypothesis testing where we draw conclusions based on data or inferential statistical groups. The null hypothesis of the Anova test is that the data is a simple random of the same population so that it has same mean and variance expectation. The aim of research is to obtain the optimum bending strength of coco fiber composite for volume fraction of 0 % fiber and 100% resin, 10% fiber and 90% resin, 20% fiber and 80%resin, 30% fiber and 70% resin, 40% fiber and 60% resin, 50% fiber and 50% resin, 60% fiber and 40% resin, 70% fiber and 30% resin with alkali treatment for two hours and without treatment, and find the result of fracture at the specimens. Based on anova analysis with error percentase 0,05 obtained F count> F crit so that answer hypothesis to fiber treatment affect mechanical properties of bending strength F = 7.752752499 F crit = 2.657197 without treatment. Keywords : Anova Test Methods, Analysis Of Composite Mechanical Properties, CoconutFibers.
Molecular phylogeny of the marine littoral genus Cafius (Coleoptera: Staphylinidae: Staphylininae) and implications for classification

Jeon, M. ‐J., Song, J.‐H. & Ahn, K. ‐J. (2012). Molecular phylogeny of the marine littoral genus Cafius (Coleoptera: Staphylinidae: Staphylininae) and implications for classification. —Zoologica Scripta, 41, 150–159.
CATCH, BY-CATCH AND INDICES OF POPULATION STATUS OF BLUE SHARK (PRIONACE GLAUCA) IN THE CANADIAN ATLANTIC

2SUMMARY The nominal catch of blue sharks in the Canadian Atlantic grossly underestimates the actual catch mortality; the sum of landed catch and by-catch mortality in the Canadian Atlantic has averaged about 1000 t annually since 1986. Several indices of population health suggest that blue shark abundance has declined, and mortality has increased, in the past decade. Median size in the catch has declined, as have standardized catch rates from both commercial longline fisheries and recreational shark tournaments. Catch curve analysis suggests a very high fishing mortality on the population. However, Petersen analysis of tag recaptures indicates that the exploitation rate in Canadian waters was <1%. Two independent approximations of total North Atlantic blue shark catch mortality suggest North Atlantic catches of more than 100,000 t and catch mortalities of 26,000-37,000 t. Blue sharks have low commercial value and are discarded in great numbers by commercial pelagic fisheries. Life table analysis indicates that blue shark populations are both productive and resilient compared to other shark species, a fact which may help explain their persistence in the face of a high overall catch mortality and a decline in relative abundance. Nevertheless, steps to reduce their mortality appear to be warranted. RESUME
Characterization of Escherichia coli isolated from cases of avian colibacillosis.

Abstract Forty-four western Canadian isolates of Escherichia coli associated with colibacillosis of turkeys and chickens were examined for serotype, antibiotic resistance, and production of aerobactin. The isolates belonged to fourteen O serogroups, with 39% of the strains being non-typeable. A high frequency of resistance to tetracycline, kanamycin, neomycin, cephalothin, streptomycin and erythromycin was observed. Most isolates produced aerobactin. Ten E. coli belonging to serogroups O1, O2 and O78 were also examined for pili production, hemagglutination, serum sensitivity, production of iron-regulated outer membrane proteins (IROMPS), and virulence. All isolates examined produced pili, exhibited mannose-sensitive hemagglutination of avian red blood cells and produced IROMPS under iron-restricted growth conditions. The five isolates of serogroup O1 and O2 were resistant to killing by turkey serum and were highly virulent. Only two of the five isolates of serogroup O78 were serum resistant. No correlation between serum resistance and virulence was observed in serogroup O78.
Long-term changes in oxygen depletion in a small temperate lake: effects of climate change and eutrophication

1. We analysed 41 years of data (1968–2008) from Blelham Tarn, U.K., to determine the consequences of eutrophication and climate warming on hypolimnetic dissolved oxygen (DO). 2. The establishment of thermal stratification was strongly related to the onset of DO depletion in the lower hypolimnion. As a result of a progressively earlier onset of stratification and later overturn, the duration of stratification increased by 38 ± 8 days over the 41 years. 3. The observed rate of volumetric hypolimnetic oxygen depletion (VHODobs) ranged from 0.131 to 0.252 g O2 m−3 per day and decreased significantly over the study period, despite the increase in the mean chlorophyll a (Chl a) concentration in the growing season. The vertical transport of DO represented from 0 to 30% of VHODobs, while adjustments for interannual differences in hypolimnetic temperature were less important, ranging from −11 to 9% of VHODobs. 4. The mean wind speed during May made the strongest significant contribution to the variation in VHODobs. VHODobs adjusted for the vertical transport of DO and hypolimnetic temperature differences, VHODadj, was significantly related to the upper mixed layer Chl a concentration during spring. 5. Hypolimnetic anoxia (HA) ranged from 27 to 168 days per year and increased significantly over time, which undoubtedly had negative ecological consequences for the lake. 6. In similar small temperate lakes, the negative effects of eutrophication on hypolimnetic DO are likely to be exacerbated by changes in lake thermal structure brought about by a warming climate, which may undermine management efforts to alleviate the effects of anthropogenic eutrophication.