Miracle-dz/UniFAR-FTUs huggingface dataset:
INTERRELATION OF PRIONS WITH NON-CODING RNAS

Prions are alternative infectious conformations for some cellular proteins. For the protein PrPC(PrP – prion protein, С – common), a prion conformation, called PrPSc(S – scrapie), is pathological. For example, in mammals the PrPScprion causes transmissible spongiform encephalopathies accumulating in the brain tissues of PrPScaggregates that have amyloid properties. MicroRNAs and long non-coding RNAs can be translated into functional peptides. These peptides can have a regulatory effect on genes from which their non-coding RNAs are transcribed. It has been assumed that prions, like peptides, due to the presence of specific domains, can also activate certain non-coding RNAs. Some of the activated non-coding RNAs can catalyze the formation of new prions from normal protein, playing their role in the pathogenesis of prion diseases. Confirmation of this assumption is the presence of the association of alleles of microRNA with the development of the disease, which indicates the role of the specific sequences of noncoding RNAs in the catalysis of prion formation. In the brain tissues of patients with prion diseases, as well as in exosomes containing an abnormal PrPScisoform, changes in the levels of microRNA have been observed. A possible cause is the interaction of the spatial domains of PrPScwith the sequences of the non-coding RNA genes, which causes a change in their expression. MicroRNAs, in turn, affect the synthesis of long non-coding RNAs. We hypothesize that long noncoding RNAs and possibly microRNAs can interact with PrPCcatalyzing its transformation into PrPSc. As a result, the number of PrPScincreases exponentially. In the brain of animals and humans, transposon activity has been observed, which has a regulatory effect on the differentiation of neuronal stem cells. Transposons form the basis of domain structures of long non-coding RNAs. In addition, they are important sources of microRNA. Since prion diseases can arise as sporadic and hereditary cases, and hereditary predisposition is important for the development of pathology, we hypothesize the role of individual features of activation of transposons in the pathogenesis of prion diseases. The activation of transposons in the brain at certain stages of development, as well as under the influence of stress, is reflected in the peculiarities of expression of specific non-coding RNAs that are capable of catalyzing the transition of the PrPCprotein to PrPSc. Research in this direction can be the basis for targeted anti-microRNA therapy of prion diseases.
Statistical analysis of daily seismic event rate as a precursor to volcanic eruptions

We analyse time series of daily seismic event rate for the Kilauea, Hawaii, volcano between 1959 and 2000. Individual eruptions are not always preceded by an increase in event rate, and many increases in event rate do not lead to eruption. However, a mean field accelerating behaviour does emerge 10–15 days before eruption in data stacked in phase with the eruption time. In phase space the pre‐eruptive dynamics is well defined by Voight's [1988] equation, but so is that of the seismicity in the period between eruptions. We conclude that the underlying dynamics of the 'background' seismicity is similar to that of magma eruption. We use Bayesian methods to compare different time‐to‐failure models that have been suggested for precursors. Only a short‐term forecast can be achieved, using a linear fit to inverse rate.
Measurement of Complex Permittivity of Polystyrene Composite at 11.64 GHz Using Cavity Perturbation Technique

─ Complex permittivity of polystyrene composites of different percentage of carbon black fillers are measured over the wide frequency range 8-12 GHz using X-band rectangular cavity resonator. The measurement technique uses the cavity perturbation technique. Validity of present measurement technique has been checked by measuring the dielectric properties of wellknown dielectric materials (Teflon and Rexolite). Polystyrene composites are very useful for lightweight shielding and absorbing materials. It would be of great interest for the community to find its dielectric properties over wider frequency range. Due to lack of experimental data on dielectric parameters of carbon black composite in literature, the experimental study has been conducted to measure the dielectric properties of polystyrene composite over wide frequency range of X-band (8-12 GHz). In addition, the estimation of measurement error associated with this technique is also discussed. Index Terms ─ Cavity perturbation, cavity resonator, complex permittivity, dielectric constant, dielectric loss, dielectric material
CHC-5137-EFP1 is an ER stress-induced glycoprotein which

sarah Appel1,2,6 susanne Vetterkind1,2,6 Ansgar Koplin1,3 Barbara Maertens1,4 Meike Boosen1,5 Ute Preuss1 1The institute of genetics, University of Bonn, Bonn, germany; 2Department of Health sciences, sargent College of Health and Rehabilitation sciences, Boston University, Boston, MA, UsA; 3Center for Molecular Biology Heidelberg (ZMBH), Heidelberg, germany; 4institute of Biochemistry ii, University of Cologne, Cologne, germany; 5institute of Pharmacology and Toxicology, University Hospital of Johann Wolfgang goethe-University Frankfurt am Main, Frankfurt am Main, germany; 6These authors contributed equally to this work
Citation for published version: Clarke, JE & Eccleston, C 2009, 'Assessing the quality of walking in adults with chronic pain: The development and preliminary psychometric evaluation of the Bath Assessment of Walking

NOTICE: this is the author’s version of a work that was accepted for publication in European Journal of Pain. Changes resulting from the publishing process, such as peer review, editing, corrections, structural formatting, and other quality control mechanisms may not be reflected in this document. Changes may have been made to this work since it was submitted for publication. A definitive version was subsequently published in European Journal of Pain, vol 13, issue 3, 2009, DOI 10.1016/j.ejpain. 2008.04. 009
Conditional Linear Cryptanalysis - Cryptanalysis of DES with Less Than 242 Complexity

In this paper we introduce a new extension of linear cryptanalysis that may reduce the complexity of attacks by conditioning linear approximations on other linear approximations. We show that the bias of some linear approximations may increase under such conditions, so that after discarding the known plaintexts that do not satisfy the conditions, the bias of the remaining known plaintexts increases. We show that this extension can lead to improvements of attacks, which may require fewer known plaintexts and time of analysis. We present several types of such conditions, including one that is especially useful for the analysis of Feistel ciphers. We exemplify the usage of such conditions for attacks by a careful application of our extension to Matsui’s attack on the full 16-round DES, which succeeds to reduce the complexity of the best attack on DES to less than 242. We programmed a test implementation of our attack and verified our claimed results with a large number of runs. We also introduce a new type of approximations, to which we call scattered approximations, and discuss its applications.
Doping-dependent intraband carrier dynamics in Landau-quantized graphene

We investigate the intraband carrier dynamics in Landau-quantized graphene after an optical excitation with low-energetic terahertz pulses. Based on a microscopic theory, we calculate time-dependent differential transmission spectra reflecting the Landau-level dynamics. Our calculations reveal a strong dependence on the Fermi energy E-F of the graphene sample as well as on the applied magnetic field B. We find that the pump pulse can lead to both absorption bleaching and absorption enhancement depending on B and the position of E-F with respect to the resonant Landau-level transition. As a result, positive and negative contributions in differential transmission spectra appear, in good agreement with recent pump-probe measurements.
Semantics in XML Data Processing

XML is good at representing data with hierarchical and self-describing structure. There is no inherent semantics with XML. However, semantics of XML has come up with us as XML is used in wide and advanced applications. This paper surveyed semantics in XML data processing environment. XML semantics can be categorized into four groups according to its usage; structural semantics, relational semantics, extended semantics, and semantic web. Relational database is still a good alternative for storing and managing large volume of XML documents. We propose an extended relational semantics in order to exploit it in managing XML documents such as query processing. 요 약 XML은 계층적이고 스스로 기술하는 구조를 가지는 데이터를 표현하기에 좋지만 XML 자체는 시맨틱을 가 지고 있지 않다. 하지만 XML이 널리 새로운 응용에서 사용됨에 따라 XML 시맨틱이 필요하게 되었다. 이 논문은 XML 데이터 처리 환경에서 시맨틱을 조사하였다. XML 시맨틱은 사용 용도에 따라 구조적 시맨틱, 관계 시맨틱, 확 장 시맨틱과 시맨틱 웹으로 분류할 수 있다. 그리고 질의 처리와 같이 XML 문서 관리에서 활용하기 위해 확장된 관 계 시맨틱을 제안한다.
Revisiting Relationship Marketing in Emerging Markets: The Case of Turkish Exportes

The purpose of this study is to explore relationship marketing in international B2B markets, with a specific focus on the impact of communication, cultural sensitivity, and shared values on relational exchange elements of commitment, trust, and export performance. The context of the study is chosen as Turkey since the number of studies on international relationship marketing in emerging market contexts needs to be increased. The model is tested upon 214 export market cases using structural equations modeling, and the findings confirm the relationships among the variables when the exporters originated from Turkey. The findings show that relationship marketing is a driver of business success and highlight the importance of cultural sensitivity as a significant driver of communication, trust, and commitment. The results imply that distributors should be sensitive to ways of doing business in Turkey and create common frames of reference with the Turkish exporters to inspire communication, trust, and commitment, all directly related to the market performance.
Codends Selectivity for Bogue ( Boops boops L., 1758) in the Eastern Mediterranean Demersal Trawl Fishery

This study investigated the selectivity of 90° turned meshes of 40 mm mesh size with 165 meshes around codend circumferences (40T1), 44 mm meshes size with 300 meshes around codend circumferences (44T1) and 44 mm mesh sizes with 150 meshes around codend circumferences (44T2). Experiments were carried out in the Kuşadası Bay of the Eastern Mediterranean, between 19 January and 29 March 2015 with commercial stern trawler. Selectivity data were collected using the covered codend method and analysed by means of a logistic equation with the maximum likelihood method. Individual hauls and mean selectivity parameter were estimated by using the CC2000 and EC-Modeller software, respectively. The mean 50% retention total length values (L50) and selection range (SR) were 12.7 cm and 2.3 cm for 40T1, 13.2 cm and 3.5 cm for 44T1 and 13.8 cm and 3.0 for 44T2, respectively. Significant differences were determined among the L50 values of the codends (between 40T1 and 44T2) (P<0.05). However, there are no statistical difference between the 40T1 and 44T1, 44T1 and 44T2 (P>0.05). On the other hand, L50 values of 40T1 and 44T1 are very close considered to the 13 cm length at first maturity size of the species.
CONTEMPORARY HEALTH PSYCHOLOGY FROM A CRITICAL PERSPECTIVE

Although there is a diversity of scientific trends and tendencies within health psychology, it could be said that this discipline of psychology consists of two main and clearly different approaches: the dominant approach of traditional (“mainstream”) health psychology and the recently developed but growing approach of “critical” health psychology. In line with this contention, in the focus of attention of this article are the current state and the newer critical trends in theory, research and practice of contemporary health psychology. The main aims of the article are the following: (1) to present the key points of difference between these two distinct approaches to health psychology, emphasizing the central conceptual and methodological developments within critical health psychology; (2) to indicate the reasons for critical rethinking existing health psychology; and (3) to suggest that critical alternative approaches are an important contribution to the further development of contemporary health psychology as an academic discipline.
The Value-Relevance of R&D Expenditure: Experience from Malaysia

This paper examines the value relevance of RD when we dropped the outliers, the result was no longer significant. These results indicate that R&D activities of capitalizers are expected to bring future benefits and consequently, lead to higher prices while the R&D activities of expensers are more difficult to evaluate given a small sample size and the presence of outliers.
Online Forums Hotspot Prediction Based on Sentiment Analysis

Problem statement: Online forums hotspot prediction is one of the sig nificant research areas in web mining, which can help people make proper decision in daily life. Online forums, news reports and blogs, are containing large volume of public op inion information. Rapid growth of network arouses much attention on public opinion, it is important t o analyse the public opinion in time and understand s the trends of their opinion correctly. Approach: The sentiment analysis and text mining are importa nt key elements for forecasting the hotspots in online forums. Most of the traditional text mining work o n static data sets, while the online hotspot forecast s works on the web information dynamically and timely. The earlier work on text information processing foc uses in the factual domain rather than opinion domain. Due to the semi structured or unstructured characteristics of online public opinion, we introd uce traditional Vector Space Model (VSM) to express them and then use K-means to perform hotspot detection, then we use J48 classifier to perform ho tspot forecast. Results: The experimentation is conducted by Rapid Miner tool and performance of proposed method J48 is compared with other method, such as Naive Bayes. The consistency between K-means and J48 is validated using three metrics. They are accuracy, sensitivity and specifi city. Conclusion: The experiment helps to identify that K-means and J48 together to predict forums hotspot. The results that have been obtained using J48 present a noticeable consistency with the results a chieved by K-means clustering.
Micromanagement basado en formaciones de grupo implementado con scripting dinámico

Resumen El exito de una partida en un juego de estrategia en tiempo real (RTS) depende de la capacidad de cooperacion y reaccion en forma adaptativa, ante los movimientos del oponente, por parte del jugador. En muchos videojuegos, esto se logra a traves del uso de las llamadas formaciones de “unidades”. El proposito de este trabajo es presentar el diseno de un micromanagement de las formaciones de grupo de agentes que se desenvuelven en un ambiente dinamico y que permite adaptar en forma “online” su comportamiento. La toma de decision del agente propuesto que decide la tactica del juego, se realiza a partir de un arbol de decision, codificado en XML, que es generado por la herramienta Weka, lo que permite automatizar el proceso de generacion del arbol de decision a partir de una base de datos. Asimismo, se presenta el diseno e implementacion de un traductor que a partir del arbol de decision en formato XML genera reglas simples IF-THEN. Los cambios “online” que se producen en el comportamiento de las formaciones, se reflejan en el juego utilizando la tecnica scripting. Dicho micromanagement fue implementado, a partir de una arquitectura propuesta de videojuegos RTS, sobre la plataforma de StarCraft: Brood War.
The complementary use of TITAN-derived radar and total lightning thunderstorm cells

The identification and trending of thunderstorm characteristics are key components of the nowcasting process. Historically, radar-identified storm attributes have been used most effectively for this process because of the WSR-88D’s extensive coverage across the United States and familiarity of use by forecasters. With the advent of lightning mapping array technology, total lightning (cloud plus cloud-toground) data is available for operational nowcasting use in many locations across the National Weather Service’s (NWS) Southern region. This paper explores the complementary use of radarand lightning-derived thunderstorm attributes using Thunderstorm, Identification, Tracking, Analysis and Nowcasting (TITAN) as a prognostic tool (Dixon and Wiener, 1993). The results from several storm events serve as the preliminary analysis necessary to introduce total lightning information into the NCAR Auto-Nowcast system (ANC; Mueller et al., 2003). The ANC is an interactive software package that integrates multiple meteorological datasets in realtime and uses fuzzy logic to combine them and create 60-minute forecasts of thunderstorm initiation, growth and decay every 5 minutes. The forecasting potential of lightning cell trends and their relation to radar reflectivity cells must be fully understood for optimal automated operational deployment in the ANC. Total lightning data has been provided across the Dallas-Ft. Worth area since 2001 via Vaisala Inc.’s second-generation Lightning Detection and Ranging (LDAR II) VHF time-of-arrival research network (Demetriades et al., 2002). The LDAR-II is an array of 7 sensors centered at Dallas-Ft. Worth International Airport with an average radial baseline of 20 to 30 km (Fig. 1). They detect pulses of radiation produced by the electrical breakdown processes of lightning in a 5 MHz band centered at 61 to 64 MHz. The expected VHF source point accuracy is better than 100 m within the network and better than 2 km out to a range of 150 km. In addition, the ANC has been running operationally in the NWS Ft. Worth, TX forecast office since March 2005 (Nelson et al. 2005). Our dataset includes 15 thunderstorms from six different events from April to July 2005 within the NWS Ft. Worth county warning area (CWA; Fig. 2).
In vitro and In vivo evaluation of streptomyces suppressions against anthracnose in chili caused by colletotrichum

The isolation of 66 streptomycetes from rhizosphere soil of chili plants was done for their inhibitory activities against three different dominant species of Colletotrichum namely C. acutatum, C. gloeosporioides and C. capsici. Twenty one streptomycetes strains were active against at least one of the Colletotrichum species. In addition, ten strains that inhibited the in vitro growth of Colletotrichum species showed chitinase activity. Strain P42, which displayed the highest inhibitory activity against all three anthracnose fungi species and high chitinase activity was tested as biological control agent in a greenhouse study. The strain successfully controlled chili anthracnose disease by significantly reducing the disease severity. Phylogenetic analysis of the 16S rRNA gene sequences showed that strain P42 belongs to the Streptomyces rochei clade. The results of the current study showed that rhizosphere-derived soil of chili plants is an important source of bioactive streptomycetes which are antagonistic against Colletotrichum.
A computational study of the effects of nozzle-exit turbulence level on the flow and acoustic fields of a subsonic jet

Five isothermal round jets at Mach number M = 0.9 and diameter-based Reynolds number ReD = 10 5 originating from a pipe nozzle are computed by Large-Eddy Simulations to investigate the effects of initial turbulence on flow development and noise generation. In the pipe, the boundary layers are tripped in order to impose, at the nozzle exit, laminar mean velocity profiles of momentum thickness equal to 1.8% of the jet radius, yielding Reynolds number Re� = 900, and peak turbulence intensities of 0, 3, 6, 9 and 12% of the jet velocity. As the nozzle-exit turbulence level increases, the shear-layer development is strongly modified. Vortex roll-ups and pairings and, more generally, coherent structures gradually disappear, leading to lower shear-layer spreading rate and rms fluctuating velocities. The jets also develop farther downstream, resulting in longer potential cores. With rising exit turbulence intensity, the noise levels generated by the present jets at ReD = 10 5 are moreover found to decrease, and to tend asymptotically towards the levels measured for jets at Reynolds numbers higher than 5 × 10 5 , which are likely to be initially turbulent and to emit negligible vortex-pairing noise. These results correspond well to experimental observations available in the literature, usually obtained separately for either mixing layers, jet flow or sound fields.
Does Providing Informal Elderly Care Hasten Retirement? Evidence from Japan

This paper examines the implications of providing care to elderly parents for adult children’s retirement plans using micro data from a Japanese survey. We find no significant effect of caregiving on family caregivers’ planned retirement age if we do not take into account caregiving intensity but find a negative and significant effect onretirement plans for intensive caregivers, particularly among women. These findings suggest that relying on family members to provide elderly care can pose a serious challenge to the ongoing efforts of the government to promote the labor supply of women and the elderly to address the shrinkage of the working-age population in Japan. The estimation results suggest that ensuring access to formal care services can help family members reconcile their paid work with caregiving requirements, thereby alleviating the adverse effect of caregiving on their retirement plans. The results also suggest that the financial burden of formal care services could require caregivers to postpone retirement in some cases.
California Wine Winners: A Hedonic Analysis of Regional and Winery Reputation Indicators

We hypothesize that quality signals improve over time with the quality performance of a wine producer, and that spillovers will affect other producers within the same region. For this purpose, we estimate a hedonic pricing model for premium California wine. Data source is the annual publication "California Wine Winners" accumulated over the judging years 1990-2001. Quality indicators for 19,583 wines are medals awarded during nine annual wine competitions, variety, regional origin, judging age as well as derived producer (brand) and regional reputation indicators. The data confirms that a wine's price is related to its own quality and to producer/regional reputation for quality.