Miracle-dz/UniFAR-FTUs huggingface dataset:
Oxytocin effects on experimental skin wound healing

Abstract Objective: Oxytocin (OXY) has significant effects on mammalian behavior. Next to its role in lactation and social interactions, it is described to support better wound healing as well. However, direct OXY effects on wound healing and the regeneration of the microvascular network are still not clarified. We therefore examined the effects of OXY and an OXY receptor antagonist [atosiban (ATO)] on skin wound healing, focusing on epithelialization and neovascularization. Methods: Skin wound healing has been assessed using intravital fluorescence microscopy in a model of full dermal thickness wounds in the dorsal skin fold chamber of hairless mice. Animals received repetitive low or high doses of OXY or ATO. Morphological and cellular characterization of skin tissue repair was performed by histology and in vitro cell assays. Results: The assessment of skin tissue repair using this therapy regimen showed that OXY and ATO had no major influence on epithelialization, neovascularization, wound cellularity, or inflammation. Moreover, OXY and ATO did neither stimulate nor deteriorate keratinocyte or fibroblast migration and proliferation. Conclusion: In summary, this study is the first to demonstrate that OXY application does not impair skin wound healing or cell behavior. However, until now, the used transmitter system seems not to be clarified in detail, and it might be proposed that it is associated with the stress response of the organism to various stimuli.
Recent geomagnetic variations and the force balance in Earth’s core

S U M M A R Y The nature of the force balance that governs the geodynamo is debated. Recent theoretical analyses and numerical simulations support a quasigeotrophic (QG), magneto-ArchimedesCoriolis (MAC) balance in Earth’s core, where the Coriolis and pressure forces equilibrate at leading order in amplitude, and where the buoyancy, Lorentz and ageostrophic Coriolis forces equilibrate at the next order. In contrast, earlier theoretical expectations have favoured a magnetostrophic regime where the Lorentz force would reach leading order at the system scale. The dominant driver (buoyant or magnetic) for the general circulation in Earth’s core is equally debated. In this study, these questions are explored in the light of the high-quality geomagnetic data recently acquired by satellites and at magnetic ground observatories. The analysis involves inverse geodynamo modelling, a method that uses multivariate statistics extracted from a numerical geodynamo model to infer the state of Earth’s core from a geomagnetic field model interpretation of the main field and secular variation data. To test the QG-MAC dynamic hypothesis against the data, the framework is extended in order to explicitly prescribe this force balance into the inverse problem solved at the core surface. The resulting inverse solutions achieve a quantitatively adequate fit to the data while ensuring deviations from the QG-MAC balance (which amount to an inertial driving of the flow) lower than each of the leading forces. The general circulation imaged within the core over the past two decades confirms the existence of a planetary-scale, eccentric, axially columnar gyre that comprises an intense, equatorially symmetric jet at high latitudes in the Pacific hemisphere. The dominant driver of this circulation is shown to be of buoyant nature, through a thermal wind balance with a longitudinally hemispheric buoyancy anomaly distribution. Geomagnetic forecasts initiated with the inverted core states are systematically more accurate against the true interannual geomagnetic field evolution when enforcing the QG-MAC constraint. This force balance is therefore consistent with the geomagnetic data at the large scales of Earth’s core that can be imaged by the method.
volumetrics eating plan

Developed by Barbara Rolls, Ph.D, this lifestylebased weight management program centers on an eating plan that is built on commonsense. This means that Volumetrics does not restrict you from eating whatever you like, but it all depends on how much you eat them. It all boils down to choosing healthier food options, such as eating whole grains, fresh fruits and vegetables, lean protein, as well as good fats. Volumetrics also recommends jazzing up your favorite dishes and turn it into a nutrition-packed meals.
Impacts of Binning Methods on High‐Latitude Electrodynamic Forcing: Static Versus Boundary‐Oriented Binning Methods

An outstanding issue in the general circulation model simulations for Earth's upper atmosphere is the inaccurate estimation of Joule heating, which could be associated with the inaccuracy of empirical models for high‐latitude electrodynamic forcing. The binning methods used to develop those empirical models may contribute to the inaccuracy. Traditionally, data are binned through a static binning approach by using fixed geomagnetic coordinates, in which the dynamic nature of the forcing is not considered and therefore the forcing patterns may be significantly smeared. To avoid the smoothing issue, data can be binned according to some physically important boundaries in the high‐latitude forcing, that is, through a boundary‐oriented binning approach. In this study, we have investigated the sensitivity of high‐latitude forcing patterns to the binning methods by applying both static and boundary‐oriented binning approaches to the electron precipitation and electric potential data from the Defense Meteorological Satellite Program satellites. For this initial study, we have focused on the moderately strong and dominantly southward interplanetary magnetic field conditions. As compared with the static binning results, the boundary‐oriented binning approach can provide a more confined and intense electron precipitation pattern. In addition, the magnitudes of the electric potential and electric field in the boundary‐oriented binning results increase near the convection reversal boundary, leading to a ~11% enhancement of the cross polar cap potential. The forcing patterns obtained from both binning approaches are used to drive the Global Ionosphere and Thermosphere Model to assess the impacts on Joule heating by using different binning patterns. It is found that the hemispheric‐integrated Joule heating in the simulation driven by the boundary‐oriented binning patterns is 18% higher than that driven by the static binning patterns.
Redox Potentials as Reactivity Descriptors in Electrochemistry

A redox catalyst can be present in the solution phase or immobilized on the electrode surface. When the catalyst is present in the solution phase the process can proceed via inner- (with bond formation, chemical catalysis) or outer-sphere mechanisms (without bond formation, redox catalysis). For the latter, log k is linearly proportional to the redox potential of the catalysts, E °. In contrast, for inner-sphere catalyst, the values of k are much higher than those predicted by the redox potential of the catalyst. The behaviour of these catalysts when they are confined on the electrode surface is completely different. They all seem to work as inner-sphere catalysts where a crucial step is the formation of a bond between the active site and the target molecule. Plots of (log i ) E versus E ° give linear or volcano correlations. What is interesting in these volcano correlations is that the falling region corresponding to strong adsorption of intermediates to the active sites is not necessarily attributed to a gradual surface occupation of active sites by intermediates (Langmuir isotherm) but rather to a gradual decrease in the amount of M(II) active sites which are transformed into M(III)OH inactive sites due to the applied potential.
Using the R&D capitalisation choice to explain the scale benefits of R&D investment

This paper helps explain a ‘puzzle’ about the scale benefits of R&D investment: although larger firms are less efficient innovators, they spend more on R&D investment and earn more from R&D investment. We find evidence suggesting that large firms enjoy a comparative advantage investing in R&D projects with less chance of success, although they do not experience such scale benefits from R&D investments with more chance of success. We capture managers’ evaluation of the chance of success of an R&D investment using an accounting choice to capitalise or expense the R&D investment. Our results have policy implications for the design of efficient and equitable allocations of R&D tax incentives between large and small firms, and for the usefulness to investors of allowing discretion in the accounting treatment of R&D expenditures. JEL Classification: M41, M48
Bayesian Parameter Inference of Explosive Yields Using Markov Chain Monte Carlo Techniques

A Bayesian parameter inference problem is conducted to estimate the explosive yield of the first atomic explosion at Trinity in New Mexico. The first of its kind, the study advances understanding of fireball dynamics and provides an improved method for the determination of explosive yield. Using fireball radius-time data taken from archival film footage of the explosion and a physical model for the expansion characteristics of the resulting fireball, a yield estimate is made. Bayesian results from the Markov chain indicate that the estimated parameters are consistent with previous calculation except for the critical parameter that modifies the independent time variable. This unique result finds that this parameter deviates in a statistically significant way from previous predictions. Use of the Bayesian parameter estimates computed is found to greatly improve the ability of the fireball model to predict the observed data. In addition, parameter correlations are computed from the Markov chain and discussed. As a result, the method used increases basic understanding of fireball dynamics and provides an improved method for the determination of explosive yields.
Carbon dioxide and methane fluxes over a boreal river measured with eddy covariance

Institute for Atmospheric and Earth System Research INAR/Physics, Faculty of Science, University of Helsinki, Helsinki, Finland. Finnish Meteorological Institute, Helsinki, Finland. Institute for Environmental Sciences, University of Koblenz-Landau, Landau, Germany. Department of Physical Geography and Ecosystem Science, Lund University, Lund, Sweden. Department of Ecology, Evolution and Marine Biology, University of California, Santa Barbara, California. Institute for Atmospheric and Earth System Research INAR/Forest Sciences, Faculty of Agriculture and Forestry, University of Helsinki, Helsinki, Finland. Faculty of Biological and Environmental Sciences, University of Helsinki, Lahti, Finland. 8Department of Earth Sciences, Uppsala University, Uppsala, Sweden.
The Third Party: Healing Eating Disorders Through a Task Model of Couples Therapy

Couples therapy is often overlooked in the treatment of eating disorders yet provides a vital role in healing and recovery. In this article we propose a four-step-task model for couples therapy when the female partner has an eating disorder. This psychodynamic model includes narrative techniques to convey pertinent personal history, attachment work, parts work, and shared communication of emotion. The article describes the composite model and details the four steps.
Where and how the East Madagascar Current retroflection originates?

<p>In-situ and remote sensing data are used to identify three states of the East Madagascar Current (EMC) southern extension: Early-Retroflection, Canonical-Retroflection and No Retroflection. Retroflections occur 47% of the time. EMC strength regulates the retroflection state, although impinged mesoscale eddies also contribute to the retroflection formation. The Early-Retroflection is linked with the EMC volume transport. Anticyclonic eddies drifting from the central Indian Ocean to the coast favour Early-Retroflection formation, anticyclonic eddies near the southern tip of Madagascar promote the generation of Canonical Retroflection, and No-Retroflection appears to be associated with a lower Eddy Kinetic Energy (EKE). Knowledge of the EMC retroflection state could help predicting: (1) coastal upwelling South of Madagascar, (2) the South-East Madagascar phytoplankton bloom, (3) the formation of South Indian Ocean Counter Current (SICC). </p>
Revision of a Failed Latarjet Procedure Using an Open Tricortical Iliac Crest Autograft Technique

Treatment of recurrent pain and instability after coracoid transfer procedure is a complex problem. This paper and accompanying video (Supplemental Digital Content 1, http://links.lww.com/TSES/A19) describe the surgical technique for revision of a failed Bristow-Latarjet procedure using a tricortical iliac crest autograft. The case presented here is a 32-year-old male with painful anterior subluxations after a Latarjet procedure because of coracoid graft pseudarthrosis. Surgical technique and result of the case are presented.
API Parameter Recommendation Based on Documentation Analysis

Application Programming Interfaces (APIs) are widely used in today’s software development, as they provide a easy and safe way to build more powerful applications with less code. However, learning how to use an API function correctly can sometimes be difficult. Software developers may spend a lot of time to learn a new library before they can become productive. When an unfamiliar API is to be used, they usually have to chase down documentation and code samples to figure out how to use the API correctly. This thesis proposes a new approach based on documentation analysis, helping developers learn to use APIs by recommending likely parameter candidates. Our approach analyzes the documentation information, extracts possible candidates from code context, and gives them as parameter suggestions. To test the effectiveness of our approach, we process the documentation of 5 popular JavaScript libraries, and evaluate the approach on top 1,000 JavaScript projects from GitHub. We used 1,681 instances of API function calls for testing in total. On average, over 60% of the time the correct parameter is in the suggestion set generated by our approach.
Removal of Reactive Red 120 from Aqueous Solutions Using Albizia lebbeck Fruit (Pod) Partical as a Low Cost Adsorbent

Synthetic dyes are using extensively in various industries such as textile, leather tanning, plastic, pulp and paper. Since this dyes are mainly toxic and even carcinogenic, discharging dye containing wastewater into the environment generates serious environmental and health consequences. Therefore, in this research investigated and evaluated the removal effect of Reactive Red 120 (RR 120) from aqueous solutions using Albizia lebbec fruit (pod) partical as a low cost adsorbent to decline mentiined undesirable consequences . In past batch adsorption investigations carried out to study various parameters including contact time, initial concentration of Reactive Red 120, pH, and adsorbent dosage. The concentration of dye was measured using a UV-vis Spectrophotometer at the wavelength of 520 nm. For analyzing data equilibrium, used from Freundlich and Langmuir isotherm models. It was found that Langmuir isotherm (R2=0.9992 and qm =1.45 mg/g) is well fitted with our data. According to thermodynamic analyzing, the process exothermic and inherent spantaneous that's it: ΔHo=9.75 J.mol-1and ΔSo=38.13 J.mol-1K-1.
Analisa Kebutuhan E-commerce untuk UKM Menggunakan Goal-Oriented Requirement Engineering (GORE)

Rekayasa kebutuhan berorientasi pada tujuan memberikan mekanisme yang sesuai untuk memahami kebutuhan aplikasi e-commerce yang diinginkan oleh pelanggan, yaitu UKM dan pembina UKM. KAOS adalah salah satu teknik pemodelan berorientasi pada tujuan yang menghasilkan kebutuhan yang lebih spesifik dan lebih mudah ditelusuri. Salah satu faktor yang menyebabkan e-commerce ditinggalakan oleh penjual dalam hal ini UKM, adalah tidak adanya akses pembiayaan dan pembinaan (seperti pendampingan/pelatihan, monitoring dan penilaian perbaikan) karena pembiayaan dan pembinaan adalah salah satu faktor kunci kesuksesan dan kegagalan suatu UKM. Penelitian ini membahas tentang model kebutuhan perangkat lunak e-commerce yang sesuai untuk UKM. Pembuatan model diawali dengan melakukan studi literature dan wawancara dengan UKM Center Universitas Universal sehingga menghasilkan tujuan (Goal) yang masih umum. Tujuan tersebut kemudian diturunkan menjadi beberapa sub-tujuan menggunakan pemodelan KAOS sehingga menghasilkan kebutuhan fungsional dan kebutuhan non-fungsional. Hasil penelitian ini menunjukkan bahwa pemodelan kebutuhan dengan menggunakaan KAOS dapat digunakan dalam memodelkan kebutuhan untuk aplikasi e-commerce yang sesuai dengan tujuan UKM dengan menghasilkan kebutuhan yang valid.
The Effects of Habitat Alteration on Anuran Diversity and Assemblages on Mount Mulanje, Malawi

Anthropogenic disturbance and increased environmental degradation often lead to losses in species diversity. As continuous forests become increasingly limited, it is important to determine conservation and biodiversity values of intact forests and surrounding landscapes. Currently, there is little data on how anuran communities react to the alarming growth of habitat degradation in tropical East Africa, nor on the value of remnant forests. This study evaluated the alpha, beta and gamma diversity of frogs in an altered landscape on Mount Mulanje, Malawi, East Africa, and assessed the impact of habitat degradation and diversity of a landscape matrix of various habitat types. Nine sites were sampled: three intact miombo forests, three eucalyptus plantations, and three secondary forests. Twenty-nine species were found throughout these landscapes. Intact miombo forests contained significantly more frog species than the other habitats. The degree of canopy cover and area size appeared to determine species diversity across all three landscapes. Although eucalyptus plantations were impoverished, naturally regenerating secondary forests can help relieve the effects of habitat alteration. Nevertheless, degraded habitats cannot substitute for continuous blocks of forest; therefore understanding these differences is crucial for maintaining the biodiversity value in the long term.
Failure of the femoral stem – condyle junction in a semiconstrained knee prosthesis. Analysis of two cases

Failure of the stem – condyle junction in a modular knee prosthesis is a rare phenomenon, but it has been described and carries serious consequences. Loosening of the femoral component increases the loads acting on the stem – condyle junction and increases the risk of fatigue fracture of the implant. The aim of this paper was to describe two cases of such damage in the revision semiconstrained prosthesis with used stems and sleeves.
Impact of the Angle of Incidence on Negative Muon-Induced SEU Cross Sections of 65-nm Bulk and FDSOI SRAMs

Muon-induced single event upset (SEU) is predicted to increase with technology scaling. Although previous works investigated the dependencies of muon-induced SEU cross sections on energy, voltage, and technology, the angle of incidence of terrestrial muons is not always perpendicular to the chip surface. Consequently, the impact of the angle of incidence of muons on SEUs should be evaluated. This study conducts negative muon irradiation tests on bulk and fully depleted silicon on insulator static random access memories at two angles of incidence: 0° (vertical) and 45° (tilted). The tilted incidence drifts the muon energy peak to a higher energy as expected. However, the SEU characteristics in the bulk device between the vertical and tilted incidences, including the voltage dependences of the SEU cross sections and multiple cells upset patterns, are similar despite the unexpected impact on the SEU cross section at an operating voltage of 0.4 V.
Strengthening Australia?s WHO Collaborating Centre for Reference and Research on Influenza

During the coming year, the WHO Collaborating Centre for Reference and Research on Influenza (the Centre) will relocate to new facilities at the Victorian Infectious Diseases Reference Laboratory? s (VIDRL) North Melbourne site. There it will expand both in size and in the scope of its activities. This is an exciting opportunity to bring together and build on the complementary strengths of two leading laboratories. A strong revitalised Centre will be key to the management of seasonal and potential pandemic influenza, as well as other emerging respiratory viruses. The Asia-Pacific region seems, disproportionately frequently, to have been the location of such emergences, of which the current global highly pathogenic avian influenza (HPAI) A H5N1 outbreak has threatened to be the greatest.
Thin accretion disk around the distorted Schwarzschild black hole

We construct the relativistic standard steady, optically thick, cold and geometrically thin accretion disk around a distorted Schwarzschild black hole. The distortion of this static and axially symmetric black hole solution, is connected to an external distribution of matter. If the effects due to the rotation are negligible, this distribution can describe the exterior of any axially symmetric astrophysical model. Also, the distortion could be related to the outer parts of the accretion disk. We study the effects due to a distortion up to the quadrupole, and compare the physical characteristics of this disk to the usual Schwarzschild case.
Single DoF Hand Orthosis for Rehabilitation of Stroke and SCI Patients

Many stroke and spinal cord injury patients suffer from paralysis which range from severe to nominal. Some of them, after therapy, could regain most of the motor control, particularly in hands if the severity level is not so high. In this paper we propose a hand orthosis for such patients whose stroke and spinal cord injury severity is nominal and the motor control in hands can be regained by therapy as part of their rehabilitation process. The patients can wear this orthosis and the therapy can be done with simple Human Computer Interface. The physicians, the physiotherapists and the patients themselves can carry out the therapy with the help of this device. The tests conducted in the lab and the results obtained are very promising that this can be an effective mechanism for stroke and spinal cord injury patients in their rehabilitation process. The hand orthosis is designed and fabricated locally so that it can be made available to such patients at an affordable cost.
Comparison of Linear Regression and Simple Linear Regression for critical temperature of semiconductor

The regression analysis plays a vital role in forecasting, estimating and predicting the material science domain. In this research work measures a statistical model to estimate the critical temperature of superconductor. This critical temperature formulated by using the superconductor’s chemical formula. The statistical model has given several measurements like Correlation Co efficient, Mean Absolute Error (MAE), Root Mean Squared Error (RMSR), Relative Absolute Error (RAE), and Root Relative Squared Error (RRSE). These measurements extracted based on atomic mass (AM), atomic radius (AR), valence(V), thermal conductivity (TC), and electron affinity (EA) contribute the most to the model’s predictive accuracy. This research work focuses the comparisons of various measurements namely Correlation Co efficient, Mean absolute error, Root Mean squared error, Relative absolute error, Root relative squared error and also time taken to build the model of leading regression algorithms like Linear and Simple Linear regression models for superconductor.