Miracle-dz/UniFAR-FTUs huggingface dataset:
Inbred strains of mice carry either one of two alleles for the Ren-1 gene on chromosome 1

Inbred strains of mice carry either one of two alleles for the Ren-1 gene on chromosome 1; Ren-1" or RenId. The Ren-ld allele is found in association with a tightly linked duplicated locus, Ren-2. The relative accumulations of renin transcripts derived from each locus were found to differ between mice with one or two renin loci in three extra renal tissues, the adrenal gland, testis, and sex accessory gland tissue. We find that the two Ren-1 alleles exhibit characteristic expression patterns in these tissues. Using genetic analyses and an allele-specific dideoxynucleotide primer extension assay we have further characterized the expression differences in these tissues. The results suggest that the all'ele-specific expression patterns observed for the Ren-1 genes are regulated by closely associated sequences in cis.
Note SCREENING OF Lycopersicon sp . ACCESSIONS FOR RESISTANCE TO Pepper yellow mosaic virus

The tomato is a crop of great economical importance, however it is susceptible to a large number of pests and diseases, including viral disease for which the best control strategy is genetic resistance. The disease, caused by Pepper yellow mosaic virus (PepYMV) has become a recent problem. Consequently, the idea of this work was to screen 376 accessions of Lycopersicon sp. to find possible sources of resistance to PepYMV. Out of 355 accessions of L. esculentum inoculated with PepYMV, 52 did not express symptoms. However, the virus reached high concentration in the tissues as measured by indirect ELISA, and therefore they were not considered as safe sources of resistance. Among 21 accessions of wild Lycopersicon species, one of L. hirsutum was shown to be resistant, with no observed symptoms. A low concentration of the virus was detected as measured by indirect ELISA. This accession seems to be suitable for breeding programs aiming at incorporating resistance for this disease into commercial tomato cultivars.
Cultural differences and board gender diversity

As evidence of the continuing interest raised by "board gender diversity", major studies (Catalyst, 2008; World Economic Forum, 2010; European Board Diversity Analysis, 2010) were recently carried out and have all led to reports confirming the imbalance of women on boards and the need to address this issue. Moreover, our analysis of these reports indicates that the low proportion of women observed on corporate boards varies across countries, which raises the question as to why? Based on institutional theory and the two sets of cultural dimensions proposed by Hofstede (1980) and House (2004), this study hypothesizes and tests whether this variation can be attributed to differences in the cultural settings. Our analysis of the representation of women on board for 5 European countries during 2006 reveals that the culture of a country indeed explains the observed differences. Of the cultural dimensions examined, power distance or a tolerance of inequality, uncertainty avoidance or a lack of tolerance for ambiguity, and masculinity or a preference for domination versus cooperation in superior/subordinate relationships have the highest explicative power for the differences in representation of women on boards that are observed around the world.
A Study on Educational Data Mining Ms

Educational data mining is an emerging field that focuses on analysing educational data to develop models to improve learning experiences and improve institutional effectiveness. It provides inherent knowledge about the delivery of education, which is used to improve the quality of teaching and learning. Effective planning can provide personalized education. The mining of educational data develops new methods to discover the knowledge of the educational database and is used for decision making in the education system. This document presents a study on various components of educational data mining along with its objectives. The objective of this document is to present a brief general description of EDM and observe the development in the field of EDM.
Placental Growth Factor-1 Attenuates Vascular Endothelial Growth Factor-A–Dependent Tumor Angiogenesis during B Cell Carcinogenesis

Members of the vascular endothelial growth factor (VEGF) family are critical players in angiogenesis and lymphangiogenesis. Although VEGF-A has been shown to exert fundamen-tal functions in physiologic and pathologic angiogenesis, the exact role of the VEGF family member placental growth factor (PlGF) in tumor angiogenesis has remained controversial. To gain insight into PlGF function during tumor angiogenesis, we have generated transgenic mouse lines expressing human PlGF-1 in the B cells of the pancreatic islets of Langerhans (Rip1PlGF-1). In single-transgenic Rip1PlGF-1 mice, intra-insular blood vessels are found highly dilated, whereas islet physiology is unaffected. Upon crossing of these mice with the Rip1Tag2 transgenic mouse model of pancreatic B cell carcinogenesis, tumors of double-transgenic Rip1Tag2;Rip1PlGF-1 mice display reduced growth due to attenuated tumor angiogenesis. The coexpression of transgenic PlGF-1 and endogenous VEGF-A in the B tumor cells of double-transgenic animals causes the formation of low-angiogenic hPlGF-1/mVEGF-A heterodimers at the expense of highly angiogenic mVEGF-A homodimers resulting in diminished tumor angiogenesis and reduced tumor infiltration by neutrophils, known to contribute to the angiogenic switch in Rip1Tag2 mice. The results indicate that the ratio between the expression levels of two members of the VEGF family of angiogenic factors, PlGF-1 and VEGF-A, determines the overall angiogenic activity and, thus, the extent of tumor angiogenesis and tumor growth. a an polyclonal the of immobilized heterodimers, enzyme-linked polyclonal for the The was developed, and heterodimer were according to the All were at least and comparable were
Effect of Pretreatments on Controlling Enzymatic Browning Before Drying of Eggplant Slices

The present study was carried out to investigate polyphenoloxidase inhibition in eggplant slices before drying. Pretreatments were carried out single or combined from immersion in ascorbic acid, citric acid or sodium chloride solutions at different concentrations 0.5, 1.0, 1.5, 2.0% and /or steaming for 2,4,6,8 min. Polyphenoloxidase activity of fresh eggplant slices was 0.65 unit /g/min. Sever inhibition was detected with increasing chemical inhibitors concentration or steam regardless of chemical inhibitors types . The inhibitory effect of steam pretreatments or various chemicals inhibitors on eggplant slices was found to decrease in the following order steam treatment > ascorbic acid > sodium chloride > citric acid at the same concentration level. Combination of chemical inhibitors and steam treatment (Ascorbic acid, citric acid, sodium chloride at levels 0.5% and steam treatment for 2min) as hurdle technology resulted most effective inhibition on enzymatic browning. Dried eggplant slices with aforementioned combined pretreatment at low concentration of chemical inhibitors and steam were less three times of enzymatic browning index than control treatment (without pretreatment). Also, inhibition of polyphenoloxidase of eggplant slices before drying were higher maintained bioactive compounds especially phenolic compounds, ascorbic acid and antioxidant activity than control.
BepiColombo SEPS Coupling Test Architecture and Coupling Test Performance Results IEPC-2015-390

This paper presents the test set-up and results of the BepiColombo SEPS Coupling Test conducted at QinetiQ Farnborough in 2014 and the subsequent coupling test results of the PCDU (Power Conditioning Distribution Unit), Battery and RIU (Remote Interface Unit). As part of the validation of the BepiColombo SEPS interfaces, a dedicated SEPS Coupling Test was performed, this included the PPU (Power Processing Unit), FCU (Flow Control Unit) and the SEPT (Solar Electric Propulsion Thruster). The system was coupled together and operated at full power with a number of diagnostics configured to demonstrate compatibility, results of which are summarised in this paper. An extension to this test included other key items of the MTM (Mercury Transfer Module), such as the PCDU, Battery and the RIU. The full chain was operated at 10KW (5KW into a load rack). Key system sequences were tested and the main power and control interfaces monitored using diagnostics, the results of which are summarised in this paper.
A bout of upper body wingate anaerobic power and capacity test alters blood rheology in untrained individuals

Melek Bor Küçükatay, Prof. Pamukkale University, Faculty of Medicine, Department of Physiology, Kinikli, Denizli, Turkey. e-mail: mbor@pau. edu.tr (orcid.org/0000-0002-9336-0205 Abstract Purpose: The aim of this study was to investigate the acute effects of a single bout of upper body wingate anaerobic power and capacity test (WAnT) on hemorheology (erythrocyte deformability, aggregation) and total oxidant/antioxidant status (TOS/TAS) in untrained individuals. Materials and methods: Fourteen sedentary healthy men ( mean age 21.86±0.55 years) performed upper body 30 s Wingate Test. Blood samples were obtained before and immediately after the exercise within 1 minute. Hemorheological parameters were determined by an ektacytometer. TOS/TAS were measured using a commercial kit and blood lactate concentration was determined by a lactate analyzer. Results: There were statistically significant decrements in RBC deformability determined at 9 shear stresses between 0.3 and 30 Pa (p<0.05). The exercise protocol induced a statistically significant increment in erythrocyte aggregation index (AI, p=0.001) and decrement in aggregation half time (t1⁄2, p=0.003). A single session of exercise resulted in acute statistically significant increments in TOS (p=0.034), hematocrit (p=0.007) and blood lactate concentrations (p=0.0001). The rise observed in TAS and the decrement in oxidative stress index did not reach statistically significant level (p>0.05). Conclusion: These data show that one session of upper body WAnT has acute effects on circulation by reducing red blood cell (RBC) deformability and increasing erythrocyte aggregation. Altered hemorheological parameters may be explained by the oxidative stress enhancing effect of exercise.
Determination of Antibacterial and Antioxidant Activities of Juniper (Juniperus oxycedrus L.) Essential Oils and Aromatic Water*

The purpose of this study was to determine the antibacterial-antioxidant properties of essential oil (EO) and aromatic water (AW) obtained from juniper fruit (Juniperus oxycedrus L.) and to investigate its possible use in animal husbandry. The EO and AW were obtained by means of distillation method from the juniper fruit collected from Isparta province. Total phenolic compounds in EO and AW were observed as 5.25, and 1.82 mg gallic acid equivalent (GAE)/ g, respectively. The highest phenolic compounds found were 77.89% α-pinene in EO and 55.43% α-cedrol in AW. The free radical trapping activity of EO and AW was found as 82 and 45.5% in 100 μl/ml, respectively. At total antioxidant capacity (TAC) analysis, this value was obtained as 27.61 mmol Trolox equiv. /lt in EO and 5.54 mmol Trolox equiv. /lt in AW. The MIC (Minimum inhibition concentration) analyses, it was observed that EO and AW suppressed the growth of Staphylococcus aureus, E. coli, Enterobacter and Salmonella bacteria in different concentrations. Besides, it was found that the effect of AW was not effective while EO suppressed the growth of Lactobacillus rhamnosus bacteria. In the preliminary study performed on calves (n= 5), adding EO and AW to milk did not have any negative effect on milk consumption. As a result of these findings, it was observed that both EO and AW had antibacterial-antioxidant activity. However, studies on live material will allow a better evaluation of the results and effects on live material.
Back-of-Device Force Feedback Improves Touchscreen Interaction for Mobile Devices

Touchscreen interaction suffers from occlusion problems as fingers can cover small targets, which makes interacting with such targets challenging. To improve touchscreen interaction accuracy and consequently the selection of small or hidden objects, we introduce a back-of-device force feedback system for smartphones. We introduce a new solution that combines force feedback on the back to enhance touch input on the front screen. The interface includes three actuated pins at the back of a smartphone. All three pins are driven by microservos and can be actuated up to a frequency of 50 Hz and a maximum amplitude of 5 mm. In a first psychophysical user study, we explored the limits of the system. Thereafter, we demonstrate through a performance study that the proposed interface can enhance touchscreen interaction precision, compared to state-of-the-art methods. In particular, the selection of small targets performed remarkably well with force feedback. The study additionally shows that users subjectively felt significantly more accurate with force feedback. Based on the results, we discuss back-to-front feedback design issues and demonstrate potential applications through several prototypical concepts to illustrate where the back-of-device force feedback could be beneficial.
Production of α-Amylase by Bacillus subtilis QM3 and its Enzymatic Properties

Alpha-amylase is a starch hydrolyzing enzyme which has many industrial applications. In this study, Bacillus subtilis QM3 has ability to produce α-amylase. Identification was done by iodine test, based on the clear zone around the sample in starch agar plates. Alpha-amylase activity was measured using 3,5-dinitrosalicylic acid (DNS). The result showed B. subtilis QM3 can produce α-amylase and activity of α-amylase was 50.58 IU/mL. The study on enzymatic properties was found: the optimum temperature is 70 ̊C, and its stability is high at 30 ̊C 70 ̊C. The optimum pH is 6.0, and the stability is high under the condition of pH was 6.0 7.0. Ca, Na, K and Mg promoted the activity of alpha-amylase, and their relative enzyme activities were 130.1%, 118.1%, 115.9% and 110.4% respectively. Fe, Zn, Cu, Mn and EDTA inhibited the activity of alpha-amylase. The relative enzyme activities were 86.1% 77.8%, 67.4%, 64.2% and 48.4% respectively.
Location-Specific Influence Quantification in Location-Based Social Networks

Location-based social networks (LBSNs) such as Foursquare offer a platform for users to share and be aware of each other’s physical movements. As a result of such a sharing of check-in information with each other, users can be influenced to visit (or check-in) at the locations visited by their friends. Quantifying such influences in these LBSNs is useful in various settings such as location promotion, personalized recommendations, mobility pattern prediction, and so forth. In this article, we develop a model to quantify the influence specific to a location between a pair of users. Specifically, we develop a framework called LoCaTe, that combines (a) a user mobility model based on kernel density estimates; (b) a model of the semantics of the location using topic models; and (c) a user correlation model that uses an exponential distribution. We further develop LoCaTe+, an advanced model within the same framework where user correlation is quantified using a Mutually Exciting Hawkes Process. We show the applicability of LoCaTe and LoCaTe+ for location promotion and location recommendation tasks using LBSNs. Our models are validated using a long-term crawl of Foursquare data collected between January 2015 and February 2016, as well as other publicly available LBSN datasets. Our experiments demonstrate the efficacy of the LoCaTe framework in capturing location-specific influence between users. We also show that our models improve over state-of-the-art models for the task of location promotion as well as location recommendation.
LIQUID JET EXPERIMENTS: RELEVANCE TO INERTIAL CONFINEMENT FUSION REACTORS

This appendix describes the experimental apparatus and techniques used in the cylindrical and sheet jet experiments. The experimental apparatus is divided into three categories; water supply system, vacuum system and elec­ tronics system. Experimental techniques include equipment calibration and measurement methods. Much credit and many thanks must go to Ron Takahashi for designing and building much of the equipment used in these experiments. The reader is referred to his thesis for design and construction details [ 1 4 ] , This appendix consists of three sections. Section 1 describes the cylindrical jet equipment and section 2 describes the sheet jet equipment. Equipment calibration and measurement methods a e described in section 3. 1. Cylindrical Jet Equipment The cylindrical jet equipment was the result of modifications to Takahashi's sheet jet equipment. The modifications (Figures B-1,2) included the installation of venturies, air traps, manometers, secondary valves, a feedthrough in the top lid, a nozzle holder and nozzles. The entire vacuum tank was inclosed in . 5" plywood with a large Lexan (polycarbonate) window (to photograph through) for protection from an implosion. The cylindrical jet equipment may be broken down into three subsystems. These are the water supply system, the vacuum system and the efedrorts system. A schematic of the cylindrical jet equipment is shown in Figure 8-1 and Figures B-3 and B-4 are photos of the equipment.
Case Study Inquiry & Black Feminist Resistance: Reflections on a Methodological Journey in the Furtherance of LIS Social Justice Research

This article explains the researcher ownership of tools of inquiry. Using personal narrative, the text highlights the elements of case study development presenting the familial as the impetus for an alternative mode for LIS social justice research in an ethnic, racial, gendered community. Using the researcher journey as an example, the approach is explored through a theoretical and methodological iterative case development process. Implications in the furtherance of LIS social justice inquiry models utilizing a critical-qualitative approach are explicated towards the development of a case study in the pursuit of community-focused research.
Supplementary Text : Highly Efficient Hypothesis Testing Methods for Regression-type Tests with Correlated Observations and Heterogeneous Variance Structure

First, we use the generalized least squares approach to estimate the weighted mean for the original data. In our case, simple sample mean is not efficient because we consider non i.i. d. data. For the mean estimation, we reformulate it into an equivalent regression model with only an intercept, Y = 1μ + , ∼ N(0,Σ), i.e. the null hypothesis case of Equation (3). For the regression model with non-i.i. d. error, weighted least square (WLS) estimator is more efficient than ordinary least square (OLS).
A framework to assess impacts of cyber attacks in manufacturing

Recent trends in manufacturing and industry accelerate the interconnection of industrial control systems between each other and over public networks. This brings an increase of cyber attack impact with it as the number of potential targets rises and the consequences of the attacks gain in severity. In order to build secure manufacturing systems, it is paramount to measure the possible impact of cyber attacks. This is required to evaluate security controls towards their effectiveness in attack scenarios. In this work, a proposal for an impact assessment framework in manufacturing is given. A suitable attacker model for execution of the attacks is provided. An evaluation metric for quantifying attack impact on manufacturing systems is developed. A light-weight modeling technique is presented and used to study the impact of cyber attacks on a cellular assembly setup. Different attack scenarios are implemented and simulated within the framework. The simulations provide detailed insight and illustrate attack impact.
L 2 -norm transformation for improving k -means clustering Finding a suitable model by range transformation for novel data analysis

In the age of increasingly pervasive sensing applications, measurement of unknown pattern phenomena resulting in novel data presents a challenge to selection of appropriate modeling tools. Because there is no rich history of domain knowledge, one can easily make early commitments to poor modeling choices. Data transformation, a solution in effort to modify the data’s geometry, can make important regularities more clear. The wrong transformation can damage the very pattern information one seeks to identify. In contrast to data transformation, we contribute an alternative method, range transformation focusing on altering the measurement tool. As a function, a model maps data inputs to a range. Focusing on transformations of the model’s range, we can ﬁnd a generally applicable way to alter the model’s properties to best suit the data. Every modiﬁcation to a function class, something we call editing the function , results in a change to the original function’s range. This work contributes a method for modifying a broad class of models to suit novel data through range transformation. We investigate range transformation for a class of information theoretic transformations and evaluate impact on classiﬁca-This
Chapter 10 Naturalisation of Normative Economics

It is almost taken for granted among economists that the ultimate goal of public policy is to provide society with more “welfare”, and the concept of welfare as well as the general strategy how to improve it is roughly the subject of studies of normative economics. The naturalisation of normative economics is an attempt to analyse the “ultimate goal of public policy” from the perspective of human cultural evolution. The “ultimate goal” is one of the “cultural variants” which may be subject to Darwinian analysis and may or may not be adaptive in given circumstances. The most important problem which is posed here is whether such analysis could be helpful in establishing that “ultimate goal” and thus to contribute to normative economics and resolve the “normative problem” (as it is rephrased in the philosophy of law). Three fundamental issues which seem to constitute the strong limits of the naturalization of the normative problem are highlighted: 1. Naturalistic ontology does not overcome the “naturalistic fallacy” indicated by Hume and Moore. 2. The epistemological perspectives in the naturalistic accounts are confused. Different normative postulates may be formulated from the individual perspective and from the perspective of the respective group, while the Darwinian analysis seems to privilege the population. 3. The genetic algorithm with endogenous fitness function seems to be nonsusceptible to “mathematical close-up”. Even if we know the initial normative order, there are limits to finding a shortcut in order to predict the future value of the fitness function. In other words, the predictability of the future social order is fundamentally restricted. M. Gorazda (*) Copernicus Center for Interdisciplinary Studies, Jagiellonian University, Krakow, Poland e-mail: marcin.gorazda@gsw.com. pl