Miracle-dz/UniFAR-FTUs huggingface dataset:
Using linked administrative data for monitoring and evaluating the Family Nurse Partnership in England: A scoping report

This report, commissioned by the FNP National Unit and undertaken by researchers at UCL and the London School of Hygiene and Tropical Medicine, presents a scoping review of how population-based linkage between data from the Family Nurse Partnership (FNP) in England and administrative datasets from other services could be used to generate evidence for commissioning, service evaluation and research. It addresses the methodological considerations, permission pathways and technical challenges of using data from the FNP linked with routinely collected, administrative data from other public services for population-based analyses, at a national and local authority level. Our ambition, when commissioning this work, was to explore whether linking data from FNP with administrative datasets might help provide a richer view about how the FNP intervention is affecting different cohorts of clients and their child after they have graduated. The report suggests that the potential for data linkage to support ongoing evaluation of a wide range of interventions including FNP at a national level is promising and an important area to explore. It makes a significant contribution to understanding the possibilities and constraints for doing this, which include barriers to data linkage at a local level (which we know is crucial for local commissioners) and the significant investment required to realise the potential of this project. We believe this report offers valuable insights other organisations interested in the delivery of evidence based policy may want to pursue.
Somatic cell-derived BMPs induce male germ cell meiosis initiation during embryonic stage via regulating Dazl expression

Germ cell fate is believed to be determined by the signaling from sexually differentiated somatic cell. However, the molecular mechanism remains elusive. In this study, ectopic initiation of meiosis in male germ cells was observed during embryonic stage by over-activating CTNNB1 in Sertoli cells. Somatic cell transcriptome and single germ cell RNA-seq analysis indicated that TGF-β signaling was activated after CTNNB1 over-activation. In vitro and in vivo experiments confirmed somatic cell-derived BMPs played crucial roles in germ cell meiosis initiation. Further studies revealed that Dazl was significantly increased in germ cells of CTNNB1 over-activated testes and induced by BMP signaling. DNMT3a and DNA methylation was also reduced in germ cells of CTNNB1 over-activated testes and increased by BMP signaling inhibitor treatment. Taken together, this study demonstrates that germ cell fate could be reprogrammed after sex determination. BMP signaling pathway is involved in germ cell meiosis initiation via up-regulating Dazl expression.
A Novel Azimuth Ambiguity Suppression Method for Spaceborne Dual-Channel SAR-GMTI

Azimuth ambiguity degrades the quality of synthetic aperture radar (SAR) images and leads to the increase of false alarm rate in ground moving target indication (GMTI). Due to the existing azimuth ambiguity, suppression methods do not remove the first-order ambiguity completely and ignore the ambiguity above first order as well, moving target detection is affected by residual ambiguity. Hence, a novel method to suppress first-order and higher order azimuth ambiguities for the dual-channel SAR/GMTI is proposed in this letter. First, the displaced phase center antenna (DPCA) technique is applied to suppress clutter. Then, estimate the local azimuth ambiguity-to-signal ratio (LAASR) to find out the area affected by ambiguity. Finally, an inpainting algorithm is improved to patch the ambiguity area. The proposed method can remove the ambiguity almost completely. Moreover, the method is verified using the GaoFen-3 SAR dual-channel complex image data, and the result shows that the false alarm of moving target detection is degraded without reducing the detection rate.
Efficient Tag Grouping via Collision Reconciliation and Data Compression

In RFID systems, tag grouping is to inform each tag in the interrogator's RF field which group it belongs to by assigning them a group ID. With this information, the reader can write the same data into a group of tags in one transmission by taking their shared group ID as the destination address, which plays a vital role in improving inventory efficiency. Existing work proposes some efficient protocols but suffers from two defects: slot waste and data redundancy. To address these problems, we in this paper propose a two-phase grouping scheme that improves the grouping efficiency via slot reuse as well as data compression. For slot waste, we try to reconcile collision slots and turn some of them into useful again by re-assigning a new slot to collision tags, which increases the number of useful slots and reduces slot waste. For data redundancy, we encode group IDs with lossless coding algorithms and reduce the data redundancy caused by repetitive transmission of group IDs. Two coding methods, Huffman coding and arithmetic coding, are adopted to shorten the length of the bit vector comprised by group IDs. Theoretical analyses and extensive simulations show that our best protocol improves the time efficiency by 51.9 percent compared with the state-of-the-art.
Energy-Efficient and Secure Air-to-Ground Communication With Jittering UAV

Unmanned Aerial Vehicle (UAV)-enabled communication platform is recognized as a promising way for secure transmission in the air-to-air and air-to-ground (A2G) networks. However, the jitter feature of UAV platform due to the absence of fixed infrastructure, the inherent randomness of airflow, and the body vibration introduces non-negligible impact on establishing robust and energy-efficient secure communication links. In this paper, we investigate energy-saving and secure transmission in a downlink A2G wiretap system considering the impact of UAV jitter. Particularly, in order to minimize the total transmission power of UAV-mounted base station, a joint beamforming optimization of confidential signal and artificial noise signal is formulated with the constraints for secrecy performance of the worst scenario. Specifically, considering the impact of UAV jittering on the antenna array response, the worst scenario indicates the A2G wiretap system with the minimum legitimate data rate and the maximum eavesdropping data rate. The non-convex problem is then reformulated with linear approximation for the channel variations and linear matrix inequality alternation for the constraints. Then, semidefinite programming relaxation is adopted to obtain the optimal solutions for the reformulated problem. Furthermore, the problem and solution are extended to the multiuser downlink wiretap system. Finally, numerical results are provided to demonstrate the impact of key system parameters on power saving under the secure transmission constraints and the UAV jitter.
Modeling the Fate of Pharmaceuticals in a Fourth‐Order River Under Competing Assumptions of Transient Storage

Quantifying the degradation of micropollutants in streams is important for river‐water quality management. While biodegradation is believed to be enhanced in transient‐storage zones of rivers, it can also occur in the main channel. Photodegradation is restricted to the main channel and surface transient‐storage zones. In this study, we propose a transient‐storage model framework to address the transport and fate of micropollutants in different domains of a river. We fitted the model to nighttime and daytime measurements of a tracer and four pharmaceuticals in River Steinlach, Germany. We could separate the surface and subsurface fractions of the total transient‐storage zone by fitting fluorescein photodegradation at daytime versus conservative nighttime transport. In reactive transport, we tested two model variants, allowing biodegradation in the main channel or restricting it to the transient‐storage zones, obtaining similar model performances but different degradation rate coefficients. Carbamazepine is relatively conservative; photodegradation of metoprolol and venlafaxine can be quantitatively attributed to the main channel and surface transient‐storage zone; metoprolol, venlafaxine, and sulfamethoxazole undergo biodegradation. We projected a decrease of overall pollutant removal under higher flow conditions, regardless of attributing biodegradation to specific river compartments. Our study indicates that model‐based analysis of daytime and nighttime field experiments allows (1) distinguishing photodegradation and biodegradation, (2) reducing equifinality of surface and subsurface transient‐storage, and (3) estimating biodegradation in different domains under different assumptions. However, entirely reducing the equifinality of attributing biodegradation to different compartments is hardly possible in lowland rivers with only limited transient storage.
Epistemological Developmental Level and Critical Skill Thinking Level in Undergraduate University Students

v Chapter One: Introduction.1 Introducing the Study. 1 Rationale. 4 Purpose.6 Key Constructs.7 Hypothesis.8 Research Questions.10 Limitations. 10 Importance of Study to Theory and Practice . 11 Chapter Two: Literature Review . 12 Critical Thinking is Important for College Students . 13 The Complexity of Defining Critical Thinking . 14 The Philosophical View.17 The Psychological View.19 The Educational View.19 Apparent Decline of Critical Thinking Skills in Collegiate Populations . 22 Epistemological Development Related to Critical Thinking . 26 Collegiate Epistemological Development . 27 Chapter Three: Methods.34 Research Questions/Hypothesis . 34 Study Participants.35 Study Design.35 Role of Researcher.37 Study Measures.38 Critical thinking instrument – Cornell Critical Thinking Test . 38 Measure of epistemological development – Kuhn epistemological instrument (KEI) . 39 Data Collection.43 Data Analysis.44 Limitations.45 Delimitations.46
Affecting factors on illness perception of patients before gynecological surgery

Objective: To examine the effective factors on illness perception of patients before gynecological surgery. Material and Methods: This cross-sectional and descriptive study was conducted on 120 female patients who were admitted to Gynecological Clinic of Trakya University Medical Faculty Hospital for gynecologic surgery between August and December 2015. Patients filled out an information form consisting socio-demographic and illness characteristics, and Brief Illness Perception Scale (IPQ-B). Results: Mean age of patients was found 51. 5Â±15.5. The treatment control (p=0.010), compliance (p
Selection of Tubular Membrane Separation based on the Resistance Performance

: Processing of fruits (such as pink guava) to produce fruit juices results in high amount of waste materials that still contain valuable by-products (e.g. antioxidants or polyphenols). Analysis of hydrodynamic resistances that considers gel layer formation as the main fouling mechanism and permeate flux decline was studied. Using tubular membrane FP 100 and ES 404 performed the experiments, with a molecular weight cut-off of 100 kDa and 4 kDa respectively. Results showed that the permeate fluxes for both of the membranes increased by increasing the Trans Membrane Pressure (TMP) and it would decrease with time. All of the resistances increased with TMP meanwhile the mass transfer of polyphenols did not affect the TMP. All the TMP resulted in similar fouling values for both membranes.
Managing Legitimacy in Business‐Driven Social Change: The Role of Relational Work

This paper examines how companies manage their legitimacy in driving social change, drawing attention to how companies proactively negotiate their involvement with nonmarket actors. Building on the legitimacy‐as‐process perspective, I argue that companies construct the legitimacy of their involvement by engaging in relational work, that is, by investing efforts in shaping their relations with others and thereby redefining roles and responsibilities. To explore the role of relational work in business‐driven social change, I present an inductive, interpretive study of a pharmaceutical company’s efforts to build a market for its products by improving diabetes care in Indonesia. Grounded in the empirical study, I develop a process model to explain how legitimacy is redefined from the bottom‐up, that is, how a company’s involvement is re‐negotiated in situ and crafted to attain the social approval of a wider audience. Advancing the micro‐foundations of nonmarket strategy, the model offers new insights into how companies can organize with nonmarket actors and how they can effectively publicize their involvement as socially responsible. I also discuss the model’s implications for a more critical research agenda on the political responsibilities of companies in social change.
IRON DEFICIENCY ANEMIA AND CURRENT STATE OF KNOWLEDGE AMONG ADOLESCENT GIRLS, LAMPUNG-INDONESIA

Background: Anemia is a condition with lower hemoglobin and hematocrit levels. The number of iron deficiency in Indonesia among children aged 5 to 14 years is still quite high at 26.4%. Less knowledge in adolescent caused by the consumption of unhealthy food or light snacks.Purpose: To describe the relationship of Iron deficiency anemia and current state of knowledge among adolescent girls in 1st Mesuji Junior High School.Methods: The type of this research is an observational study with a cross-sectional method. The population of this study was members of all adolescent girls in class VIII and IX at 1st Mesuji Junior High School with the total is 87 respondents. Data collected by a questionnaire and analyzed used chi-square.Results: The most of the respondents 47 (54%) had poor knowledge about Iron deficiency anemia and experienced of Iron deficiency anemia 44 (50.6%) with p-value = 0.001. Conclusion: There is a relationship between Iron deficiency anemia and current state of knowledge among adolescent girls, Mesuji Junior High School in 2018. It is recommended for school management to further improve health promotion or counseling about Iron deficiency anemia in adolescent girls, especially in prevention.
Family and Moral Development

This chapter draws on a myriad of theoretical backgrounds and past research as a comprehensive foundation for discussion that focuses on how family members (e.g., parents, siblings, extended family) are important in the socialization of diverse aspects of moral development (e.g., emotions, cognitions, behaviors) and how these moral outcomes in turn influence family relationships. The majority of research focuses on how parents, especially mothers, influence the development of morality, whereas a paucity of research exists that analyzes the influence of siblings and extended family on moral development. Some areas of moral development are better developed (e.g., moral emotions and behaviors) and others remain relatively less explored (e.g., moral identity). At the conclusion of the chapter, avenues for future research are discussed.
Computational Studies of Drug Repurposing Targeting P-Glycoprotein-Mediated Multidrug Resistance Phenotypes in Priority Infectious Agents

ABCB1 P-glycoprotein (P-gp) is an ATP-dependent efflux pump with broad substrate specificity associated with cellular drug resistance. Homologous to role in mammalian biology, P-glycoproteins of bacterial and fungal pathogens mediate the emergence of multidrug resistance phenotypes, with widespread clinical/ socioeconomic implications. This work aims to characterize P-gp homologues in certain WHO-prioritized infectious agents, namely (1) bacteria: Acinetobacter baumannii and Staphylococcus aureus and (2) fungi: Aspergillus fumigatus , Candida albicans , and Cryptococcus neoformans . PSI-BLAST searches against the genome of each of these organisms confirmed the presence of P-gp homologues. Each homologue was aligned against five known P-gp structures, for structural modeling. FDA-approved antibiotics used in the current line of therapy were retrieved from PubChem, and potential antibiotics were identified based on similarity and repurposing of the existing drugs. The most tenable target-ligand conformations from docking studies of the respective modeled P-gp structures and the antibiotic ligands were assessed for interacting residues within 4.5 Å of the ligand, probable binding pockets and relative efficacies of the new drugs. Our studies could lay the foundation for the development of effective synergistic or new therapies against these pathogens.
Adoption of Newcastle disease vaccines by smallholder households in Tanzania

by Zoe Alexandra Campbell, Ph.D. Washington State University May 2019 Chair: Guy H. Palmer Veterinary vaccines contribute to the maintenance of animal health, control of animal diseases, and improvement of the socioeconomic well-being of people living in low and middleincome countries who rely on livestock as a source of livelihood; however, benefits cannot be realized unless vaccines are used. Newcastle disease (ND) vaccines enhance smallholder chicken production but uptake by chicken-owning households in Tanzania is estimated at only 22% by the 2012 National Census of Agriculture. We examined low uptake from the household perspective with the goal of informing strategies to increase vaccine coverage. An interdisciplinary, mixed methods approach incorporated a cross-sectional survey of 535 households across three regions to identify determinants and barriers to vaccine adoption, double-bounded contingent valuation to assess willingness to pay for vaccines, and focus groups to identify preferences between two vaccines types. Eighty percent of households were aware of
A geometric characterization of population coding in the prefrontal cortex and hippocampus during a paired-associate learning task

Large-scale neuronal recording techniques have enabled discoveries of population-level mechanisms for neural computation. However it is not clear how these mechanisms form by trial and error learning. In this paper we present an initial effort to characterize the population activity in monkey prefrontal cortex (PFC) and hippocampus (HPC) during the learning phase of a paired-associate task. To analyze the population data, we introduce the normalized distance, a dimensionless metric that describes the encoding of cognitive variables from the geometrical relationship among neural trajectories in state space. It is found that PFC exhibits a more sustained encoding of task-relevant variables whereas HPC only transiently encodes the identity of the stimuli. We also found partial evidence on the learning-dependent changes for some of the task variables. This study shows the feasibility of using normalized distance as a metric to characterize and compare population level encoding of task variables, and suggests further directions to explore the learning-dependent changes in the population activity.
Aging and Degradation of Optical Fiber Parameters in a 16-Year-Long Period of Usage

ABSTRACT The first generation of installed optical cables in Eastern Europe has been in use for more than 20 years. This paper analyzes the change of optical fibers from the aspect of aging under the influence of transmitted signals and the aspect of parameter degradation during exploration. The paper provides the answer for how to repair the increased attenuation at 1310 nm. We also proposed the method of solution NG PON access for small remote villages that are situated along the analyzed route.
Preliminary Analysis of the Diet of Triturus carnifex and Pollution in Mountain Karst Ponds in Central Apennines

Mountain karst ponds are sensitive environments, hosting complex trophic networks where amphibians play a major role, often as top predators. The diet of the Italian crested newt (Triturus carnifex) is still poorly known for populations occupying mountain karst ponds. These are traditionally used as livestock’s watering points, leading to water pollution due to excreta and wading behavior. The aim of this paper is to understand the relationship between T. carnifex diet composition, assessed through the stomach flushing technique, and physical and chemical characteristics in mountain ponds, focusing on parameters altered by livestock pressure, such as ammonium concentration and dissolved oxygen. The high diversity of prey items found within the newts’ gut contents confirms the generalist diet even in mountain ponds. The number of prey taxa, their relative abundance and Shannon–Wiener diversity index show variations among the sampled sites, related to livestock organic pollution. Moreover, we report the very first European records of microplastic items in amphibians’ stomach content, which also represent the first evidence for Caudata worldwide. Our findings suggest that livestock pressure directly influences T. carnifex diet and highlight that the emerging issue of plastics is a threat even in remote high-altitude environments.
Automatic labelling of lesions using radiofrequency feature discrimination

Poster: "ECR 2017 / C-1855 / Automatic labelling of lesions using radiofrequency feature discrimination" by: "N. Ridley1, A. Iriarte2, L. Tsui2, C. Bore2, M. Shere2, I. Lyburn3, P. Bannister2; 1Swindon/UK, 2Bristol/UK, 3Cheltenham/UK"
Gaining insights on the influence of attention, anxiety, and anticipation on pain perception

Purpose This article highlights the influence of attention and pain anticipation on pain attenuation. Pain-related trait anxiety was found to moderate the effect that attention strategies impose on pain perception. This article may contribute to clinical treatments quality, where pain attenuation effect is desired. Participants and methods One hundred seven participants, comprising of 72 (67%) females and 35 (33%) males between the age of 17 and 48 (M=22.6, SD =4.36), were used in the analysis. The current study measured the effect of pain anticipation and attention on three aspects of pain perception: threshold, tolerance, and perceived pain intensity. Pain anticipation was manipulated by varying the amount of information given to participants about a future pain stimulus. Attention was manipulated through a sensory focusing task and a distraction task. Participants were randomized into 1) InfoControl group with distraction task trial (n=30), 2) InfoControl group with attention to pain trial (n=26), 3) InfoExtra group with distraction task trial (n=26), or 4) InfoExtra group with attention to pain trial (n=25). The pain stimulus was delivered in a form of heat. The moderating effects of pain-related trait anxiety on these variables were also investigated using Pain Anxiety Symptom Scale Short Form. Results Two structural equation models revealed that anticipation is not a predictor of pain perception and neither did it interact with pain-related trait anxiety. However, attention strategies do significantly relate to pain perception. Furthermore, pain-related anxiety was a significant moderator of attention and pain attenuation. These findings imply that the effectiveness of attention strategies in attenuating pain is affected by individuals’ pain-related trait anxiety. Conclusion The results suggest the importance of appointing the appropriate attention strategy to different individuals with varying level of trait anxiety. Future explorations are necessary to develop a more specific understanding on the nature of information and distractions on pain perception.