Miracle-dz/UniFAR-FTUs huggingface dataset:
Analysis on discard of blood and its products with suggested possible strategies to reduce its occurrence in a blood bank of tertiary care hospital in Western India

Background: Blood is precious and should be utilized judiciously with minimal wasting. By analyzing the data and the reasons for discard, the blood transfusion service can develop plans to evaluate causes that lead to discard of blood and its components and interventions that can be used to optimize their use by training and education. Aim: (1) The aim of the study was to evaluate causes that lead to discard of blood and its components and interventions that can be used to optimize their use by training and education, (2) to introduce possible strategies for minimizing blood wastage, and to observe and compare the discard rate after the implementation of strategies. Materials and Methods: The study of analysis on discard of blood and its products was carried out retrospectively from January 2014 to December 2016 (36-month period), and the data were collected from the blood bank database system using Easy Software in the Department of Transfusion Medicine, Shri M P Shah Govt. Medical College, Jamnagar in Western India. The results were analyzed using Microsoft Excel 2007 database sheet, percentage calculated and Chi-square test was applied between different variables with P value set a significant when <0.05. Results: A total of 66,255 blood units were collected during the study period of 36 months. Out of 66,255 blood units collected, 44,617 were whole blood (WB) whereas components were prepared from remaining blood units. A total of 21,638 packed red blood cells (PRBCs), 6840 platelet concentrate (PC), and 14,372 fresh frozen plasma (FFP) were prepared. Average discard rate of the present study was 6.95%. Discard rate for WB, PRBC, PC, FFP was 3.15%, 2.26%, 28.39%, and 5.36%, respectively. Conclusion: To minimize wastage of blood, there should be proper implementation of blood transfusion policies and coordination between hospital and blood bank staff. Strict adherence to donor selection criteria, taking proper predonation history and counseling, software to identify transfusion transmitted infection (TTI) positive donors, and deferring suspected professional donors who have been screened previously may help in reducing discard due to TTI positivity. Process improvements such as technical expertise in phlebotomy, prevent red blood cells (RBC) contamination during platelet and FFP preparation, precaution during thawing of FFP to prevent leakage, and increased use of apheresis technique prevent wastage of blood components. Continued medical education for technical staff to maintain self-audit, tracking quality indicators of processing and preparation of the blood components, rational use of blood and components, and review the blood management system will further help in reducing the discard rate.
Research overview of hydrogen production from biomass: A bibliometric analysis of the research published during the 1979-2019 period

The purpose of this paper is to develop a conceptual analysis of hydrogen production from biomass research in literature by quantifying the main bibliometric performance indicators, identifying the main authors, countries, journals and research areas and evaluating the intellectual structure and evolution of the field using SciMAT as a bibliometric analysis software. In this way, the methodology implemented in this research encompasses both the bibliometric performance analysis and science mapping approaches of biomass-based hydrogen production research themes. The bibliometric performance analysis is centered on the citation-based impact of the scientific output, while science mapping illustrates the evolution of the research themes that build the field through the use of bibliometric network analysis techniques. The publications related to biomass-based hydrogen production research available at Scopus have been compiled between 1979 and 2019 (876 publications). Finally, the paper provides objective evidence of the evolution of the hydrogen production from biomass field, which confirms the interest that researchers have in this theme to develop new capabilities. Finally, it offers a framework to support researchers evaluating the field and, finally, to assist them in the development and direction of their future analysis identifying trends in terms of research.
The Future of Healthcare Internet of Things: A Survey of Emerging Technologies

The impact of the Internet of Things (IoT) on the advancement of the healthcare industry is immense. The ushering of the Medicine 4.0 has resulted in an increased effort to develop platforms, both at the hardware level as well as the underlying software level. This vision has led to the development of Healthcare IoT (H-IoT) systems. The basic enabling technologies include the communication systems between the sensing nodes and the processors; and the processing algorithms for generating an output from the data collected by the sensors. However, at present, these enabling technologies are also supported by several new technologies. The use of Artificial Intelligence (AI) has transformed the H-IoT systems at almost every level. The fog/edge paradigm is bringing the computing power close to the deployed network and hence mitigating many challenges in the process. While the big data allows handling an enormous amount of data. Additionally, the Software Defined Networks (SDNs) bring flexibility to the system while the blockchains are finding the most novel use cases in H-IoT systems. The Internet of Nano Things (IoNT) and Tactile Internet (TI) are driving the innovation in the H-IoT applications. This paper delves into the ways these technologies are transforming the H-IoT systems and also identifies the future course for improving the Quality of Service (QoS) using these new technologies.
Pre-service teachers’ Perceived Concerns and Benefits during Practicum

The study focused on pre-service teachers’ benefits from teaching practice, and the problems they experienced during practicum. Using document analysis method, the data were obtained from their portfolios which included self-evaluation forms, weekly journal entries, and summary reports of their teaching experience. The results indicate that a) teaching practice is a turning point for pre-service teachers, b) it was the practicum opportunity rather than the coordinating teachers’ support that mattered, c) selection of the coordinating teachers was not done effectively, d) longer-service coordinating teachers followed conventional methods, e) the more practical the university courses the less problems the pre-service teachers experienced.
Interplay between TERT promoter mutations and methylation culminates in chromatin accessibility and TERT expression

The telomerase reverse transcriptase (TERT) gene is responsible for telomere maintenance in germline and stem cells, and is re-expressed in 90% of human cancers. Contrary to common concepts, CpG methylation in the TERT promoter (TERTp), was correlated with TERT mRNA expression. Furthermore, two hotspot mutations in TERTp, dubbed C228T and C250T, have been revealed to assist binding of transcription factor ETS/TCF and subsequent TERT expression. This study aimed to elucidate the combined contribution of epigenetic (promoter methylation and higher-order chromatin structure) and genetic (promoter mutations) mechanisms in regulating TERT gene expression in healthy skin and in melanoma cell lines (n=61). We unexpectedly observed that the methylation of TERTp was as high in a subset of healthy skin cells, mainly keratinocytes, as in cutaneous melanoma cell lines. In spite of the high promoter methylation fraction in wild-type (WT) samples, TERT mRNA was only expressed in the melanoma cell lines with high methylation or intermediate methylation in combination with TERT mutations. TERTp methylation was positively correlated with chromatin accessibility and expression in 8 melanoma cell lines. Cooperation between epigenetic and genetic mechanisms were best observed in heterozygous mutant cell lines as chromosome accessibility preferentially concerned the mutant allele. Combined, these results suggest a complex model in which TERT expression requires either a widely open chromatin state throughout the promoter in TERTp-WT samples due to high methylation or a combination of moderate methylation fraction/chromatin accessibility in the presence of the C228T/C250T mutations. Author summary PvdV and RvD formulated research goals and aims and supervised the overall progress. Wet-lab experiments, preparation of the manuscript and statistical analysis were performed by CS and CR. CS designed the novel assays. RN was involved in the experimental setup. RvD, NG and PvdV were responsible for funding acquisition. CR, RN, NG, RvD and PvdV critically reviewed the manuscript.
Moral stances and moral language in reports investigating child protection in Finland

ABSTRACT In 2012, an eight-year-old girl was murdered in Finland by her father and her father’s spouse. The death of this girl, who was already known to child protection services and other support organizations, drew attention to problems in Finland’s child protection system and led to the commissioning of several public investigations. Reports on these investigations were published as separate reports in 2013 and 2014. This study assessed the moral stances on children taken in three reports through a philosophical analysis of the moral language contained in them. The analysis yielded four themes: children’s voice, rights, a good childhood, and vulnerability. The reports included both explicit and implicit moral stances towards children. Because these reports have an impact on child protection practices, their moral stances on children need to be explicitly studied and discussed.
Value Formulation of Digital Health Technologies – A Multiple Case Study on the Implementation of an Intelligent Patient Flow Management System

Author Tuomo Tanila Title of thesis Value Formulation of Digital Health Technologies – A Multiple Case Study on the Implementation of an Intelligent Patient Flow Management System Degree programme Industrial Engineering and Management Major/minor Strategy and Venturing Code SCI3050 Thesis supervisor Paul Lillrank Thesis advisor(s) Henni Tenhunen Date 29.7. 2019 Number of pages 102+3 Language English Abstract Aging populations set challenges to healthcare systems on a global scale, thus increasing demand for new technological solutions. As a result, investments in new digital health technologies are constantly increasing. Yet the value of these solutions is difficult to measure. Although many evaluation models for digital health interventions exist, there seems to be a lack of proper explanation of the mechanisms behind the value formulation.Aging populations set challenges to healthcare systems on a global scale, thus increasing demand for new technological solutions. As a result, investments in new digital health technologies are constantly increasing. Yet the value of these solutions is difficult to measure. Although many evaluation models for digital health interventions exist, there seems to be a lack of proper explanation of the mechanisms behind the value formulation. This thesis explores a novel approach to evaluate and structure value formulation for digital health interventions. Utilizing a CIMO-logic (context, intervention, mechanisms, and outcomes) in a multiple case study, this study set out to apply a recently developed value formulation model, PROVE-IT, for a digital health intervention for seeking of treatment and triage purposes. The research problem was divided into three objectives. The first aim was to discover the mechanisms explaining the functionality of the examined intervention. Second, the thesis explored how the relationship between the mechanisms and outcomes can be measured. Third, the ultimate goal was to develop the existing model to be more practical and generalizable for all digital health interventions. The CIMO-logic was perceived to be a suitable tool for evaluating digital health interventions and their dynamics. Despite differences in contexts, the mechanisms for each case were found to be very similar, thus questioning the generalizable characteristic of the model. As a result, this research suggests further actions to clarify each section in the PROVE-IT model besides presenting means to apply practical metrics to operationalize the model. This thesis contributes to the existing evaluation literature by providing a new approach for value formulation by emphasizing the mechanism perspective. Furthermore, this study provides insight into the practical use of value formulation model to be utilized in sales narratives of health technology companies.
Isolated LLC converter for PEV charging for wide‐range voltage gain using six‐switch bridge

This paper proposes a dual LLC converter based on a six‐switch bridge to charge deeply depleted plug‐in electric vehicle onboard battery packs. The primary‐side switch network comprises an input series or parallel, and two types of transformer‐independent modes. Thus, there are four operation modes. In the input series mode, normalized voltage gains are scaled to 0.5; therefore, a low output voltage can be obtained. In addition, in the input parallel mode, the normalized voltage gains are scaled to 2.0. These four modes operate at the resonant frequency at the switching frequency. Therefore, the efficiency performance can be optimized over a wide output voltage range. The validity of the proposed system is confirmed with a 1‐kW prototype.
Effect of the basic surface properties of woven lining fabric on printing precision and electrical performance of screen-printed conductive lines

Conductive lines are essential for the integration of electronic devices into fabrics, and their direct screen printing on fabrics is a promising, simple and low-cost method for mass-manufactured textile-based conductive lines. However, the intrinsic porous structures and texture characteristic of textiles complicate the diffusion and penetration of conductive ink, and will deteriorate the printing precision and electrical performance of conductive lines. To establish the relationship between the surface characteristics (i.e. porosity, roughness, contact angle) and printing precision as well as electrical performance, the screen-printed conductive lines on six different nylon woven lining fabrics were examined and compared. Moreover, to study the printing precision and the minimum printable line width on woven lining fabric, conductive lines with different widths were screen printed. The results showed that the fabric substrate with the smallest pore size and roughness shows a higher printing precision and lower electrical resistance of screen-printed conductive lines. Relatively, the dynamic contact angle and wetting time of ink on the surface of the fabric have a significant effect on the printing precision. Therefore, the surface structure of the fabric substrate determines to some degree the printing precision of conductive lines, the printable minimum line width and its electrical properties. It is believed that these findings will provide some important support for screen printing flexible electronic devices on woven textiles.
Effects of Dance and of Tai Chi on Functional Mobility, Balance, and Agility in Parkinson Disease: A Systematic Review and Meta-analysis

Introduction: Parkinson disease has symptoms that can be reduced by integrative therapy. Objective: To verify the integrative therapy effects with motion mobility, balance, and agility in people with Parkinson disease. Methods: A systematic review with meta-analysis was performed for randomized, nonrandomized, and semirandomized controlled trials. Results: A total of 122 studies were found, with 9 being selected, for people with Parkinson disease. The intervention varied from 2 weeks to 12 months, with dance and Tai Chi. Conclusion: The dance and Tai Chi brought no significant differences in balance and agility. Tai Chi improved mobility compared with other therapies.
Ocurrencia de Limnoraphis robusta (Parakutty) Komárek et al. (Oscillatoriales, Cyanobacteria) en el embalse Hanabanilla (Cuba Central)

espanolEn muestras de fitoplancton del embalse Hanabanilla (Cuba Central) se observo el crecimiento masivo de Limnoraphis robusta (Parakutty) Komarek et al. (Oscillatoriales) conocida anteriormente para Africa, Brasil, Guatemala, India y Norteamerica. Aunque el material cubano coincide en casi todos los caracteres con - , no forma los tipicos estratos (mats), sino aparece formando aglomerados (clusters). Tambien la poblacion cubana presenta individuos con menores dimensiones. En el presente trabajo se ofrece la descripcion de la poblacion cubana, asi como informaciones acerca de su taxonomia, distribucion y ecologia. EnglishA filamentous cyanobacteria was observed in plankton samples from Hanabanilla Reservoir (Central Cuba). Based on optical microscopy study, the Cuban specimens correspond with Limnoraphis robusta (Parakutty) Komarek et al. (Oscillatoriales) known from Africa, Brazil, India, Guatemala and North America. According to the literature consulted this taxon was not previously reported from Cuban freshwaters. The colonies of the Cuban population form clusters not the typical mats described for the species. The specimens are also characterized by smaller cells and trichomes. The present paper offers description of the Cuban population and data about its taxonomy, geographical distribution and ecology.
PENERAPAN ANALISIS CLUSTER ENSEMBLE DENGAN METODE ROCK UNTUK MENGELOMPOKKAN PROVINSI DI INDONESIA BERDASARKAN INDIKATOR KESEJAHTERAAN RAKYAT

Kesejahteraan rakyat pada suatu daerah dapat dilihat dari indikator-indikator yang mampu mengukur kesejahteraan rakyat. Kesejahteraan rakyat pada masing-masing daerah berbeda-beda. Oleh karena itu dapat dilakukan pengelompokan daerah di Indonesia untuk melihat kemiripan kondisi kesejahteraan rakyat di suatu daerah dengan daerah lain sehingga dapat membantu pemerintah dalam menyusun dan menentukan prioritas pembangunan. Data indikator kesejahteraan berupa data campuran. Metode pengelompokan yang dapat digunakan untuk menangani data campuran yaitu metode cluster ensemble dengan menggunakan algoritma CEBMDC (Cluster Ensemble Based Mixed Data Clustering) dengan melakukan pengelompokan untuk data numerik dan data kategorik secara terpisah, selanjutnya hasil pengelompokan digabungkan. Objek pengamatan pada penelitian ini adalah 34 provinsi di Indonesia. pengelompokan untuk data numerik menggunakan metode hirarki agglomerative menghasilkan pengelompokan terbaik dengan nilai CP terkecil diperoleh pada metode Ward dengan 2 cluster. pengelompokan data kategorik menggunakan metode ROCK (Robust Clustering Using Links) dengan nilai CP∗ terbesar diperoleh pada θ = 0.30 yang menghasilkan 4 cluster. Tahap penggabungan (ensemble) menggunakan metode ROCK menghasilkan pengelompokan terbaik pada θ = 0.30 dengan nilai CP∗ terbesar yang menghasilkan 4 cluster yang terdiri dari 1 provinsi pada cluster 1, 19 provinsi pada cluster 2, 10 provinsi pada cluster 3, dan 4 provinsi pada cluster 4.Kata Kunci: Cluster Ensemble, CEBMDC, ROCK, CP, CP∗
Pixel Antenna Optimization Using $N$ -Port Characteristic Mode Analysis

A method for using <inline-formula> <tex-math notation="LaTeX">${N}$ </tex-math></inline-formula>-port characteristic mode analysis (<inline-formula> <tex-math notation="LaTeX">${N}$ </tex-math></inline-formula>-port CMA) for the design and optimization of pixel antennas is described. The motivation for using <inline-formula> <tex-math notation="LaTeX">${N}$ </tex-math></inline-formula>-port CMA is to determine the fundamental resonance characteristics of the pixel antenna geometry and optimize them directly. An advantage of this approach is that it separates the process of antenna resonance optimization from impedance matching. It contrasts directly with conventional optimization approaches based on return loss which implicitly perform impedance matching together with antenna resonance optimization. In our work, an objective function based on modal significance is utilized and genetic optimization is used to optimize the desired characteristics. An efficient method for the implementation of <inline-formula> <tex-math notation="LaTeX">${N}$ </tex-math></inline-formula>-port CMA is described which requires only one full-wave simulation of the pixel geometry in the optimization process. Impedance matching is performed as a final step in the design process after optimization of the antenna resonance is completed. Simulation and experimental results are provided to demonstrate the utility of the approach. Examples include a triband antenna design for GSM900 (880–960 MHz), DCS1800 (1710–1900 MHz), and IMT-E2600 (2500–2690 MHz), and a dual-band antenna design for GSM900 (890–960 MHz) and DCS + PCS + UMTS bands (1710–2170 MHz).
An Ecosystem for Improving the Quality of Personal Health Records

The integration of healthcare data networks with personal health record (PHR) systems can reduce unnecessary duplication of lab tests and medical treatment errors, as well as empower patients with the ability to self-manage their own health. However, facilitating health data exchange between the healthcare data networks and the PHR systems is difficult due to the complexity of data sharing agreements, and the costly interfaces that have to be set up between those institutions. A hybrid PHR system architecture can combine the benefits of portable and online PHRs, providing more ubiquitous access to the PHR, while alleviating the need for establishing complex data sharing agreements and costly system interfaces. This architecture must, however, address issues such as PHR data integrity, data misinterpretation, security of the portable and online PHR, as well as privacy. Patients may tamper with their own records for reasons such as hiding a history of drug abuse or avoiding incarceration. We address the PHR data integrity issue by leveraging standardized encryption and digital signature schemes. Patients allowed access to their records may misinterpret intermediary notes by physicians. This can result in more unnecessary encounters with the physician. We resolve the data misinterpretation issue by providing physicians with the ability to store intermediary notes that are only accessible by other physicians. The threat of compromise of a patient’s mobile device is tackled by using trusted platform hardware security features in order to launch the mobile application from which the patient can access and manage their PHR. Direct access to the mobile device allows for other attack vectors, such as malicious traffic interception hardware. Our mobile direct access control protocol, built on provably secure cryptographic primitives, aims to provide security from such attack vectors. Privacy issues are tackled with cryptographic access control that employ provably secure primitives, and the use of oblivious search and access, adapted for a multi-client setting and with support for access control. We present a preliminary security assessment of the system, that provides an overview of potential attack scenarios.