Miracle-dz/UniFAR-FTUs huggingface dataset:
Emotional and Cognitive Responses of Children Attending Summer Camps in Occupied Palestine: A Pilot Study

Background: The current study sought to address the lack of evaluation for summer camps which seek to offer emotional and cognitive support for children in occupied Palestine. Objective: To assess children’s emotional and cognitive response to summer camps, children who attended camps were compared to those who did not attend on a standardised measure of emotion and cognition within situations of adversity. Methods: A mixed methods quasi-experimental post-test only design was used.Children, aged 8-10 years, who attended a summer camp (n=62), were compared to those who had not attended a camp (n=22) on the Child Post-traumatic Cognitions Inventoryand on a qualitative summer experience questionnaire. Camp workers (n= 16) also completed a summer experiences questionnaire for comparison of perceptions betweenworkers and children. Statistical analysis involved t-test and ANOVA for within and between group differences and a six-step quasi-qualitative analysis was used to assess summer experience questionnaire responses. Results: Unexpectedly,children who had attended a summer camp presented higher levels of traumatic cognition; however, they also reported more hopefulness for the future than children who did not attend a camp. It is uncertain if camp attendees are a self-selecting group because of higher levels of traumatic exposure and/or cognitions or because summer camps may have unintended negative consequences. Conclusion: The current study, with its unexpected results, emphasises the importance of embedding evaluation into summer camp delivery. More robust experimental designs, however, are necessary in order to be confident that the outcomes are related to program rather than contextual factors. A range of potential summer camp and environmental influencing factors on outcomes were identified for future research.
New applications of heterologous gene expression in Hansenula polymorpha for protein and metabolite production

The methylotrophic yeast Hansenula polymorpha has been established as a highly efficient expression system. Strong promoters derived from the methanol metabolism pathway and mitotically stable high-copy integration have made this organism very effective for heterologous protein expression. To improve the processing of secretory proteins targeted by the MFα prepro sequence, variations in the amino acid composition near the processing site of Kex2p were investigated (Manuscript I). The insertion of Ala-Pro between MFα prepro sequence and protein of interest leads to an improved processing of the signal sequence in case of interleukin-6 (IL-6) and interferon-α 2a (IFNα-2a). Modeling of the transition sequences confirmed a better exposition of the Kex2p-cleavage site in dependency of Ala-Pro insertions. Analysis of the secreted proteins revealed activity of an Ala-Pro specific endoprotease. Partial removal of the N-terminal Ala-Pro dipeptide was also detected during IFNα-2a processing. The putative protease responsible for the processing of Ala-Pro dipeptides was identified by gene deletion. Significant similarities with Saccharomyces cerevisiae Ste13p were identified. To generally improve productivity in the H. polymorpha system new fusion protein strategies were investigated (Manuscript II). The recombinantly strongly expressed cytosolic ferritin heavy chain (FTH1) was analyzed with regard to its potential as fusion partner for difficult-to-express target proteins. A fragment of the parathyroid hormone (PTH) was chosen to explore whether fusion to FTH1 enhances PTH stability. We could show that the expression level of this fusion protein was at least of the magnitude of that of FTH1 without fusion partner. The solubility of the fusion protein was increased in comparison to FTH1 alone and no degradation of PTH occurred when fused C-terminally to FTH1. Ectoine and 5-hydroxyectoine belong to the family of compatible solutes which are known to contribute to the adaptation of the cell to osmotic stress by mediation of a constant turgor. H. polymorpha was engineered to express the enzymes of the H. elongata 5-hydroxyectoine biosynthesis pathway (Manuscript III). Expression of the enzymes EctB, EctA, EctC and EctD in H. polymorpha resulted in production of 5-hydroxyectoine in gram per liter scale with almost full conversion of ectoine to 5-hydroxyectoine. We showed that 5-hydroxyectoine synthesis was influenced by feeding of methanol during cultivation. Furthermore, 5-hydroxyectoine synthesis was downregulated by the addition of methionine, lysine or threonine indicating the existence of a feedback regulated aspartate kinase in H. polymorpha.
Combinatorial bijections from hatted avoiding permutations in $S_n(132)$ to generalized Dyck and Motzkin paths

We introduce a new concept of permutation avoidance pattern called hatted pattern, which is a natural generalization of the barred pattern. We show the growth rate of the class of permutations avoiding a hatted pattern in comparison to barred pattern. We prove that Dyck paths with no peak at height $p$, Dyck paths with no $ud. du$ and Motzkin paths are counted by hatted pattern avoiding permutations in $\s_n(132)$ by showing explicit bijections. As a result, a new direct bijection between Motzkin paths and permutations in $\s_n(132)$ without two consecutive adjacent numbers is given. These permutations are also represented on the Motzkin generating tree based on the Enumerative Combinatorial Object (ECO) method.
Development of a BLDC motor drive with improved output characteristics

A brushless DC (BLDC) motor control based on rotor position sensing scheme is discussed in this paper. A PIC microcontroller is employed to generate pulse width modulation (PWM) signals for driving the power inverter bridge. Parameters required for power PWM generations have been programmed, which provide flexible and online source code modifications in accordance with the motor and circuit requirements. Hardware implementation and simulation results show the effectiveness of the developed motor drive. The flexibility offered by the developed motor control and drive enables the implementation of difference control algorithms for improving the output characteristics of the BLDC motor. Streszczenie. W artykule przedstawiono sterowanie silnikiem bezszczotkowym DC bazujące na czujnikach pozycji wirnika. Mikrokontroler jest wykorzystywany do wytwarzania sygnalu PWM zasilającego przeksztaltnik. Parametry wymagane do generacji sygnalu PWM są programowane w zalezności od wymagan silnika i napedu. Badania modelu i symulacje pokazują skutecznośc zaproponowanej metody. (Naped silnika bezszczotkowego z ulepszoną charakterystyką wyjściową)
A Review on Semantic Approach using Nearest Neighbor Search

Information retrieval (IR) of acquiring information sources relevant to an information sources from a group or unit. Ontology in IR field is used to represent an official domain description in addition a semantic layer is added to the IRS. The idea depicts in relating semantics on the concepts of ontology using query words. Semantic approach, focus to search effectively by assuming the searchers contextual meaning and purpose the way they occur in terms. It aims to improve the search for hospitals with its specialties relevant to disease given through text analysis. Distance from search location can be viewed in map view. A technique called spatial inverted index to locate multidimensional information and draws algorithms which will acknowledge nearest neighbor queries. Nearest neighbor can locate the hospitals that are closest to a given address.
Design System of Cell Type Assembly Machine with Dual Arms Robot by GA

The purpose of this research is to develop a system named DELUGA which automatically decides by genetic algorithm (GA) where to place a lot of assembled parts, jigs and robot hands in the workstation when designing a cell type assembly machine with a dual arms robot. In DELUGA, since the left and right robot arms simultaneously perform assembly work, adopt the concept of waiting time to prevent interference between the left and right arms. The cycle time from assembly to completion is used as fitness, GA operation is performed, and better arrangement is decided.
Walking activity and its determinants in free-living ambulatory people in a chronic phase after stroke: a cross-sectional study

Abstract Background: Free-living walking activity and its contributing factors in ambulatory people with stroke is poorly investigated. Objective: Evaluating free-living walking activity and identifying factors associated with free-living walking activity. Methods: In this cross-sectional study, participants wore an accelerometer to measure their level of walking activity. They also completed the Berg Balance Scale (BBS) and the Timed Up and Go test for functional balance, the Falls Efficacy Scale, the 10-Metre Walk Test and the Geriatric Depression Scale to investigate the relation between the performance tests and walking activity. Results: The 38 analyzed participants were on average 62 (±11.4) years old and 66 (IQR 64.8) months post stroke. They took an average of 3048.3 ± 1983.1 steps, had 123.3 ± 61.3 walking bouts a day and walked for 32.5 ± 18.2 min a day. Their average speed was 90.3 ± 13.8 steps a minute. The multivariate linear analysis showed that the BBS was the only determinant that was significantly related to all outcomes, except walking bouts. Conclusion: Free-living walking activity levels in ambulatory people with chronic stroke are low. The BBS is an independent significant predictor of free-living walking activity. Implications for rehabilitation Free-living walking activity can be expressed in different outcomes measured by accelerometry. Free-living walking activity levels in ambulatory people with chronic stroke are low, therefore support to sustain walking in the own environment should be part of the rehabilitation program after stroke. Balance is an important related factor to free-living walking activity which needs attention during rehabilitation after stroke.
Mechanisms responsible for reduced erythropoiesis during androgen deprivation therapy in men with prostate cancer.

Androgen deprivation therapy (ADT) is a mainstay of treatment for prostate cancer (PCa). As androgens stimulate erythropoiesis, ADT is associated with a reduction in hematocrit, which in turn contributes to fatigue and related morbidity. However, the mechanisms involved in ADT-induced reduction in erythropoiesis remain unclear. We conducted a 6-mo prospective cohort study and enrolled men with PCa about to undergo ADT (ADT-Group) and a control group of men who had previously undergone prostatectomy for localized PCa and were in remission (Non-ADT Group). All participants had normal testosterone levels at baseline. Fasting blood samples were collected at baseline, 12 wk, and 24 wk after initiation of ADT; samples were obtained at the same intervals from enrollment in the Non-ADT group. Blood count, iron studies, erythropoietin, erythroferrone, and hepcidin levels were measured. Seventy participants formed the analytical sample (31 ADT, 39 Non-ADT). ADT was associated with a significant reduction in erythrocyte count (estimated mean difference = -0.2×106 cells/µl, 95%CI = -0.3 to -0.1×106 cells/µl, P < 0.001), hematocrit (-1.9%, 95%CI = -2.7 to -1.1%, P < 0.001), and hemoglobin (-0.6 g/dl, 95%CI = -0.8 to -0.3 g/dl, P < 0.001). Serum hepcidin concentration increased in the ADT-group (18 ng/ml, P < 0.001); however, iron concentrations did not change (-1.1 µg/dl, P = 0.837). Ferritin levels increased in men on ADT (60 ng/ml, P < 0.001). Iron binding capacity, transferrin saturation, erythroferrone, and erythropoietin did not change. Nine men undergoing ADT developed new-onset anemia. In conclusion, reduced proliferation of marrow erythroid progenitors leads to ADT-induced reduction in erythropoiesis. Future studies should evaluate the role of selective androgen receptor modulators in the treatment of ADT-induced anemia.
The Influence of Pterocladia capillacea Extract on Growth and Antioxidant System of Cicer arietinum

Seaweeds are exposed to a combination of oxygen and light and this leads to the production of free radicals (Zubia et al., 2007). Seaweeds protect themselves against free radicals by developing antioxidant defense system, including enzymatic and non-enzymatic (Halliwell and Gutteridge, 2001; Burtin, 2003; Ashraf and Foolad, 2007; Piotrowska-Niczyporuk and Bajguz, 2013). International Journal of Current Microbiology and Applied Sciences ISSN: 2319-7706 Volume 5 Number 4 (2016) pp. 1062-1073 Journal homepage: http://www.ijcmas. com
A Dynamic Changepoint Model for New Product Sales Forecasting

At the heart of a new product sales-forecasting model for consumer packaged goods is a multiple-event timing process. Even after controlling for the effects of time-varying marketing mix covariates, this timing process is not a stationary one, which means the standard interpurchase time models developed within the marketing literature are not suitable for new products. In this paper, we develop a dynamic changepoint model that captures the underlying evolution of the buying behavior associated with the new product. This extends the basic changepoint framework, as used by a number of statisticians, by allowing the changepoint process itself to evolve over time. Additionally, this model nests a number of the standard multiple-event timing models considered in the marketing literature. In our empirical analysis, we show that the dynamic changepoint model accurately tracks and forecasts the total sales curve as well as its trial and repeat components and other managerial diagnostics e.g., percent of triers repeating.
User Presence Inference via Encrypted Traffic of Wireless Camera in Smart Homes

Wireless cameras are widely deployed in smart homes for security guarding, baby monitoring, fall detection, and so on. Those security cameras, which are supposed to protect users, however, may in turn leak a user’s personal privacy. In this paper, we reveal that attackers are able to infer whether users are at home or not, that is, the user presence, by eavesdropping the traffic of wireless cameras from distance. We propose HomeSpy, a system that infers user presence by inspecting the intrinsic pattern of the wireless camera traffic. To infer the user presence, HomeSpy first eavesdrops the wireless traffic around the target house and detects the existence of wireless cameras with a Long Short-Term Memory (LSTM) network. Then, HomeSpy infers the user presence using the bitrate variation of the wireless camera traffic based on a cumulative sum control chart (CUSUM) algorithm. We implement HomeSpy on the Android platform and validate it on 20 cameras. The evaluation results show that HomeSpy can achieve a successful attack rate of 97.2%.
Putting all One’s Eggs in One Basket: Relational Contracts and the Provision of Local Public Services

French municipalities often contract out the provision of local public services to private companies, and regularly choose the same private operator for a range of different services. We develop a model of relational contracts that shows how this strategy may lead to better performance at lower cost for public authorities. We test the implication of our model using an original database of the contractual choices made by 5000 French local public authorities in the years 2001, 2004 and 2008.
Participants' motivations to contribute to biodiversity citizen science projects

The public participation in scientific projects (citizen science) is significantly increasing specially with technology developments in recent years. Volunteers play an essential role in citizen science projects, therefore understanding their motivations, and understanding how to sustain them to keep contributing to the project are of utmost importance. This paper presents the analysis of volunteers’ characteristics and their motivations to contribute to a citizen science project, which aims at encouraging citizens to take action for biodiversity. The results from the online survey illustrate that people are more motivated by intrinsic nature-related motives rather than extrinsic motivations.
Transition from Suppressed to Active Convection Modulated by a Weak Temperature Gradient–Derived Large-Scale Circulation

AbstractNumerical simulations are performed to assess the influence of the large-scale circulation on the transition from suppressed to active convection. As a model tool, the authors used a coupled-column model. It consists of two cloud-resolving models that are fully coupled via a large-scale circulation that is derived from the requirement that the instantaneous domain-mean potential temperature profiles of the two columns remain close to each other. This is known as the weak temperature gradient approach.The simulations of the transition are initialized from coupled-column simulations over nonuniform surface forcing, and the transition is forced in the dry column by changing the local and/or remote surface forcings to uniform surface forcing across the columns. As the strength of the circulation is reduced to zero, moisture is recharged into the dry column and a transition to active convection occurs once the column is sufficiently moistened to sustain deep convection. Direct effects of changing surfa.
Responsiveness of Minimal Clinically Important Change for the Persian Functional Rating Index in Patients with Chronic Low Back Pain

Study Design A prospective, within-group cohort study of 46 patients with chronic low-back pain (CLBP). Purpose To assess the responsiveness of the Persian Functional Rating Index (PFRI) and to determine the minimal clinically important change (MCIC) of the PFRI in a cohort of patients with CLBP. Overview of Literature The FRI is an instrument for assessing pain and disability in patients with low-back pain. No study so far has examined the responsiveness of the PFRI. Methods Forty-six patients with CLBP with a mean age of 50.33±14.28 completed the PFRI, the Persian Roland–Morris Disability Questionnaire (PRMDQ), and a Visual Analog Scale (VAS) before and after 10 physiotherapy sessions. A Global Rating of Change Scale (GRCS) was completed after treatment. Results The changes in PFRI scores were statistically significant using the paired t-test (p<0.001). The PFRI revealed high effect sizes (range, 0.93–1.82). The PFRI showed significant correlations with the VAS (0.86), the PRMDQ (0.66), and the GRCS (0.45). The area under the receiver operator characteristic curve for the PFRI was good (0.76; 95% confidence interval, 0.56–0.95). The MCIC for PFRI was 10.63 points. Conclusions The results supported the responsiveness of the PFRI in patients with CLBP and showed the amount of change in PFRI scores perceived as worthwhile by the patients.
Structure, function and regulation of drug/xenobiotic transporter

OF THE THESIS ii ACKNOWLEDGEMENTS iv DEDICATION v TABLE OF CONTENTS vi LISTS OF TABLES ix LIST OF FIGURES x CHAPTER 1 Overview 1 1.1 Organic Anion Transporter (OAT) Family 1 1.2 OAT Substrates Specificity 4 1.3 OAT Structure 6 1.4 OAT transport mechanisms and physiological roles 7 1.5 Regulation of OAT 9 1.6 Clinical Implications 12 1.7 Important Issues Remained To Be Addressed 13 CHAPTER 2 The Role of GXXXG Motifs In The Expression And Function of hOAT1 14 2.
Highlights of Mass Spectrometric Methodologies in Environmental Pollution

1.1 The integrated pest management (IMP) Phytodrugs or, more commonly, pesticides are chemical devices of both natural and synthetic origin playing an important role in crop protection. International agencies presiding environmental control have recently issued many directives to avoid pollution due, among others, to chemical treatment of fields by agricultural farms. The role of chemical analysis through the many platforms available by applying modern mass spectrometric methods, has become, therefore, of primarily importance either for the control of the health of our planet and for the welfare of many developing and undeveloped countries. The state-of-the-art of agriculture chains in the world could be represented by a survey published by Botswana scientists on the knowledge and perception of pests, diseases and pest management practices by local vegetable farmers (Obopile et al., 2008). The results showed that pesticides were used and that seven out of twenty-four of them are considered extremely or highly hazardous by the World Health Organisation. Conversely, it is well known that worldwide starving requires a wider distribution of goods, many of them coming from agriculture. Integrated pest management (IPM) represents the only reliable approach helping producers in preserving their crops, therefore training on efficient and safe use of pesticides is needed to minimise their use. Comprehensive studies for each particular problem posed by pest infections are also vital for an environmental friendly approach to the unavoidable use of pesticides (El-Bouhssini et al., 2009; Gennaro et al., 2003). Mass spectrometry is an affordable chemical method suitable, for its specificity and sensitivity, to deal with identification and assay of molecules in complex mixtures. The method has been implemented in the last years in its sampling, ionizing and analyzing facilities thus allowing molecules from few to million Daltons to be detected. Hyphenation with chromatographic devices helps in the analyses of complex mixtures, whereas parallel and concomitant detection of the separated analytes with other systems such as ultra violet (UV) spectroscopy, pulsed flame photometric (PFPD) (Amiray & Jing, 1998; De Nino et al., 2003) and electrochemical (EC)(Kullman &. Matsumara, 1996; Garrido-Frenich et al., 2001) detectors are determinant in many applications. The evaluation of organophosphates in oranges carried out by GC/MS/PFPD allowed an easy assignment of the analytes in extracted mass chromatogram (A, figure 1).
THE EFFECTIVENESS OF AUTOMATED THAI DOCUMENTS CATEGORIZATION BASED ON MACHINE LEARNING

The purpose of this research was to test the effectiveness of the Thai language document categorization model by using the features of reduction and machine learning techniques. The experimental results showed that the support vector machine algorithm used to classify Thai documents did so with a highest efficiency of 93.06%, followed by naïve-bayes and decision tree at 86.80% and 76.51% respectively. Considering the parameter that had the best efficiency, support vector machine algorithm with 7000 features had the best performance at 93.90%. The features could be reduced significantly without affecting the performance of categorization.