Miracle-dz/UniFAR-FTUs huggingface dataset:
Effects of Academic Motivation on Clinical Practice-Related Post-Traumatic Growth among Nursing Students in South Korea: Mediating Effect of Resilience

Post-traumatic growth (PTG) refers to personal growth that occurs after experiencing challenges. For many nursing students, PTG could occur during their clinical practice. Academic motivation and resilience could help students to overcome these traumatic clinical experiences and possibly achieve PTG. This study examined the relationships between nursing students’ academic motivation and resilience leading to post-traumatic growth. A total of 291 nursing students from three South Korean nursing colleges participated in this cross-sectional study. Self-report questionnaire data were analyzed using t-tests, ANOVA, correlations, and hierarchical multiple linear regressions. Intrinsically motivated students’ PTG scores were significantly higher compared to extrinsically motivated students (t = 4.62, p < 0.001). Resilience scores showed similar results (t = 3.81, p < 0.001). Significant total, direct, and indirect effects of academic motivation on resilience and PTG were found. In addition, resilience mediated 40.9% of the relationship between academic motivation and PTG. Nursing students with intrinsic academic motivation were more likely to achieve high PTG scores, and resilience mediated the relationship between academic motivation and PTG. It is suggested that the importance of academic motivation must be considered in the early stages of university-level nursing education to increase retention rates of nursing students.
Power-aware optimization of baseband-function placement in cloud radio access networks

Because of the advent of highly diverse and heterogeneous services, 5G networks required the design of a new paradigm in terms of Radio Access Networks. The Centralized- RAN appeared as a suitable solution, enabling the reduction of costs by centralizing the baseband functions. Nevertheless, it requires very high bandwidth, making it unfeasible. Functional splits were proposed to divide the protocol stack and place the baseband functions in Central Units (CU) or Distributed Units (DU). It is an efficient way of enabling different types of services while reducing costs for operators. However, each split option introduces very stringent constraints in terms of latency, throughput and processing. The problem that arises is how to optimally place the CU functions in the network nodes. This paper proposes an optimization framework to minimize link and node power, subject to the split requirements. We also present models to compute bandwidth, computational effort and latency for splits 2 (PDCP-RLC) and 6 (MAC-PHY). The solution proposed was compared to the fully centralized and distributed scenarios over a realistic topology of a metro network with 24-hour traffic. Results show that the proposed CU-placement optimization reduces the power consumption in respect to both scenarios in split 2. In addition, even if the consumption is very similar to the centralized scenario in split 6, the ILP solution meets the latency requirements. Finally, when comparing the split options, the overall power consumption in split 2 is 5% lower than split 6.
Comparison of adaptive null-steering algorithms for low power GNSS phased arrays

GNSS are widely used in everyday life, for navigation, precision aircraft landing, high-frequency trading and power distribution networks. However there are always people who wish to deny access, often for reasons such as car theft or drug trafficking. As such it is of interest to many parties to be able to quickly identify and mitigate jamming. To this end, a low power, phase incoherent, detection system was designed. Exhaustive searches are inefficient and so it is proposed that bio-inspired optimisation algorithms will improve the search speed. Two algorithms were implemented and simulated, and their performance compared for both static tests and for tracking a moving jammer. It was found that both algorithms would locate a jammer faster than an exhaustive sweep. However when a moving jammer was introduced, Particle Swarm Optimisation was unable to reliably track, while Invasive Weed Optimisation could easily track both ramps and step changes in position.
Segmentation and machine learning techniques applied to automatic detection of diseases from eye-fundus retina images

Here are presented some methods of retina image processing for retina image segmentation of blood vessels, using the ARIA and B-COSFIRE filters methods, with noise reduction. Eye-fundus images are used for experiments for noise removal with KSVD and BM3D methods also we use an image contrast enhancement (CLAHE) method: Contrast limited adaptive histogram equalization. Is presented also an efficient method of image segmentation based on a nature inspired optimization technique namely Particle Swarm Optimization. In the end machine learning techniques are applied to automatic detection of diseases from retina eye-fundus images with automatic classification.
Development of a semiquantitative PCR assay for the detection of the Clostridium perfringens type C beta toxin gene in purified nucleic acid extracts from the intestinal tract of pigs

Total DNA was extracted and purified from luminal digesta samples (1 g) of 14-week-old (c. 43 kg bodyweight) pigs. Digoxigenin (DIG) labelled PCR products of the beta toxin gene of Clostridium perfringens type C were generated with DIG-11-UTP and chemoluminescent signals of DIG-labelled PCR products were detected on slot blots and recorded with a sensitive charge coupled densitometric camera. Detection limit and correlation of chemoluminescent signals to initial target DNA concentration were evaluated. Detection of the beta toxin gene could be achieved with 100 ag C. perfringens DNA in the presence of 1 μg unspecific DNA. The semiquantitative DIG-PCR assay was used to evaluate the relative abundance of the beta toxin gene of C. perfringens type C in purified DNA extracts from intestinal samples of pigs, which were fed a wheat/barley diet (controls), supplemented with the antibiotic avilamycin (40 mg/kg feed), a xylanase (4000 U/kg feed) or a combination of both feed additives. The antibiotic treatment significantly reduced the amount of PCR product in ileal and colon DNA extracts. Xylanase supplementation significantly reduced the amount of PCR product in colon samples, but led to an increase in jejunal samples. From the results it is concluded, that the antibiotic inhibited growth of C. perfringens type C in the ileum and colon of pigs. The semiquantitative DIG-PCR assay can be used to sensitively monitor the relative abundance of specific pathogens in the intestinal tract.
Early Perturbations in Glucose Utilization in Malaria-Infected Murine Erythrocytes, Liver and Brain Observed by Metabolomics

Investigation of glucose utilization during an infection is central to the study of energy metabolism. The heavy utilization of glucose by the malaria parasite, and the consequences of this process, have been investigated extensively. However, host glucose utilization during early infection has not been explored to date. In a first attempt, this article investigates the changes in the host glucose utilization in Balb/c mice infected with Plasmodium berghei ANKA using 13C-labeled glucose infusion followed by NMR spectroscopy. The results suggested significant alterations of liver, brain and red blood cell (RBC) glucose utilization during early infection when the parasitemia was <1%. At the pathway level, we observed a decrease in the shunt metabolite 2,3-bisphosphoglycerate in the RBCs. Glycolysis and pathways associated with it, along with fatty acid unsaturation, were altered in the liver. Significant changes were observed in the central carbon metabolic pathways in the brain. These results have implications in understanding the host physiology during early infection and pave the way for detailed flux analysis of the proposed perturbed pathways.
TEST OF THE FIRST-COHORT ADVANTAGE HYPOTHESIS WITH FEATHERTAIL GLIDERS (MARSUPIALIA)

Abstract The first-cohort advantage hypothesis (FCAH) was formulated to explain patterns of biased sex ratios in litters of Virginia opossums (Didelphis virginiana). Females of this species typically produce 2 litters each season, and litters born early in a season are male-biased and those born later in the season are female-biased. Males born earlier are older and heavier in the next breeding season and likely to secure more mates. The hypothesis predicts fitness benefits to mothers that have more males in their 1st litter (the 1st cohort) each season. The feathertail glider (Acrobates pygmaeus), in Victoria, Australia, is another species that produces 2 litters per year and not all males mature before the start of the breeding season after their birth. Hence, feathertail gliders also might be expected to show a pattern of sex bias in litters consistent with the FCAH. They do not. This paper uses data from 2 field studies of feathertail gliders in Victoria over the past 18 years. Sex ratios were recorded for 53 first- and 42 second-cohort litters. There was a trend toward male-biased litters in the 1st cohort, but also in the 2nd, and neither group differed significantly from a binomial distribution of sex ratios. This provides no support for the FCAH in this species. This may be due to the much less sharply defined breeding seasons in feathertail gliders compared to those of Virginia opossums, and to their greater longevity.
Home-range changes by brushtail possums in response to control

Common brushtail possums (Trichosurus vulpecula) are intractable pests in New Zealand. The effectiveness of local control can be limited by immigration, some of which has been attributed to a ‘vacuum effect’ – directed movements induced by the control itself. To characterise the vacuum effect we examined changes in the home ranges of trapped possums following control in a 6-ha block at one end of a 13-ha forest patch on farmland near Dunedin, New Zealand. We also monitored a sample of possums by radio-telemetry. After control, the density was 3 ha–1 inside the removal area and 16 ha–1 outside. During the year after the removal, 29% of possums within 100 m of the boundary of the removal area (n = 38) shifted their range centre at least 50 m towards it. The effect diminished rapidly with distance: only 1 of 28 animals moved more than 200 m from the boundary. The size of the previous range was a significant predictor of movement among males, but this may be partly a sampling artifact. We measured a net flux of 69 possums km–1 across the boundary in the 12 months after control, and possums settled on average 44 6.9 m inside the boundary. The vacuum effect in brushtail possums appears largely confined to home-range adjustments by individuals with ranges overlapping the area of reduced density. This limits its potential role in population recovery.
Recovering from forest-to-pasture conversion: leaf decomposition in Central Amazonia, Brazil

Abstract: Land-use change in tropical forests can affect the micro-environment for decomposition under modified canopies. In turn, decomposition may have consequences for soil fertility and ecosystem sustainability. The effects of the conversion from primary forest to pastures on leaf-litter decomposition and its recovery in secondary forests 20 y after pasture abandonment were evaluated using litterbags and a general mixed model approach. Litterbags containing leaf-litter of two contrasting qualities were placed in those three ecosystems and the mass remaining after 90 d was quantified. The mass remaining was 50% lower in high- than in low-quality leaves. The effects of the decomposition environment depended on the substrate quality. Although differences among ecosystems were not significant for low-quality leaves, high-quality leaves decomposed more slowly in pastures than in forests (mean dry mass remaining was 38% in pastures, 14% in secondary and 12% in primary forest). The decomposition of common substrates did not differ among forests. Results show that the conversion of primary forest to pasture may produce conditions for slower decomposition; however, these conditions appear be restored to a great extent in 20-y-old secondary forests.
Proteomic Profiling of Serum Exosomes From Patients With Metastatic Gastric Cancer

Background: Clinical management of metastatic gastric cancer (mGC) remains a major challenge due to a lack of specific biomarkers and effective therapeutic targets. Recently, accumulating evidence has suggested that exosomes play an essential role in cancer metastasis and can be an excellent reservoir of novel biomarkers and candidate therapeutic targets for cancer. Therefore, in this study, we aimed to reveal the proteomic profile of mGC-derived exosomes. Methods: Exosomes were isolated from pooled serum samples of 20 mGC patients and 40 healthy controls (HC) by ultracentrifugation. Next, quantitative proteomic analyses were applied to analyze the protein profiles of the exosomes, and bioinformatic analyses were conducted on the proteomic data. Finally, the expression of exosomal protein candidates was selectively validated in individual subjects by western blot analysis. Results: We isolated exosomes from serum samples. The size of the serum derived exosomes ranged from 30 to 150 nm in diameter. The exosomal markers CD9 and CD81 were observed in the serum exosomes. However, the exosomal negative marker calnexin, an endoplasmic reticulum protein, was not detected in exosomes. Overall, 443 exosomal proteins, including 110 differentially expressed proteins (DEPs) were identified by quantitative proteomics analyses. The bioinformatics analyses indicated that the upregulated proteins were enriched in the process of protein metabolic, whereas the downregulated proteins were largely involved in cell-cell adhesion organization. Surprisingly, 10 highly vital proteins (UBA52, PSMA1, PSMA5, PSMB6, PSMA7, PSMA4, PSMA3, PSMB1, PSMA6, and FGA) were filtered from DEPs, most of which are proteasome subunits. Moreover, the validation data confirmed that PSMA3 and PSMA6 were explicitly enriched in the serum derived exosomes from patients with mGC. Conclusion: The present study provided a comprehensive description of the serum exosome proteome of mGC patients, which could be an excellent resource for further studies of mGC.
Prototypical pacemaker neurons interact with the resident microbiota

Significance Here, we discover prototypical pacemaker neurons in the ancient cnidarian Hydra and provide evidence for a direct interaction of these neurons with the commensal microbiota. We uncover a remarkable gene-expression program conservation between the Hydra pacemaker neurons and pacemaker cells in Caenorhabditis elegans and the mammalian gut. We suggest that prototypical pacemaker cells emerged as neurons using components of innate immunity to interact with the microbial environment and ion channels to generate rhythmic contractions. The communication of pacemaker neurons with the microbiota represents a mechanistic link between the gut microbiota and gut motility. Our discoveries improve the understanding of the archetypical properties of the enteric nervous systems, which are perturbed in human dysmotility-related conditions. Pacemaker neurons exert control over neuronal circuit function by their intrinsic ability to generate rhythmic bursts of action potential. Recent work has identified rhythmic gut contractions in human, mice, and hydra to be dependent on both neurons and the resident microbiota. However, little is known about the evolutionary origin of these neurons and their interaction with microbes. In this study, we identified and functionally characterized prototypical ANO/SCN/TRPM ion channel-expressing pacemaker cells in the basal metazoan Hydra by using a combination of single-cell transcriptomics, immunochemistry, and functional experiments. Unexpectedly, these prototypical pacemaker neurons express a rich set of immune-related genes mediating their interaction with the microbial environment. Furthermore, functional experiments gave a strong support to a model of the evolutionary emergence of pacemaker cells as neurons using components of innate immunity to interact with the microbial environment and ion channels to generate rhythmic contractions.
Laboratory Culture and Preliminary Characterization of the Nitrogen-Fixing Rhizosolenia-Richelia Symbiosis

(.) Nitrogen-fixation by the symbiont could sustain the symbiosis. Growth and nitrogenase activity demonstrated light saturation kinetics, with no photoinhibition up to 315 μE. m -2 . s -1 for growth and 780 μE. m -2 . s -1 for nitrogen fixation. The symbiosis is not obligate for Rhizosolenia, which is capable of growth independent of the symbiont if a nitrogen source is available. The symbion is contained in the periplasmic space between the Rhizosolenia plasmalemma and frustule, and preliminary evidence suggests excretion of fixed nitrogen into the medium may be occuring
Understanding the Perceived Mental Health of Canadians During the COVID-19 Pandemic.

BACKGROUND While the physical health implications of the COVID-19 pandemic are regularly publicly available, the mental health toll on Canadians is unknown. This article examines the self-perceived mental health of Canadians during the COVID-19 pandemic and explores associations with various concerns after accounting for socioeconomic and health factors. DATA The cross-sectional Canadian Perspectives Survey Series 1 collected information related to COVID-19 in late March and early April 2020 concerning labour market participation, behaviours, and health for the Canadian population 15 years and older living in the 10 provinces. METHODS Socioeconomic and health characteristics of respondents as well as concerns about the impact of COVID-19 were examined to determine differences in experiencing excellent or very good compared to good, fair or poor perceived mental health. RESULTS Just over half of Canadians aged 15 and older (54%) reported excellent or very good mental health during the COVID-19 pandemic. Several concerns were also associated with mental health. Notably, after considering the effects of socioeconomic and health characteristics, women, youth, individuals with a physical health condition and those who were very or extremely concerned with family stress from confinement were less likely to report excellent or very good mental health. DISCUSSION These findings point to particular risks for lower perceived mental health during the COVID-19 pandemic. Results highlight various concerns of Canadians which may be associated with mental health, in particular, family stress in the home.
A narrative review of heart rate and variability in sepsis

Clinicians face challenges in the timely diagnosis and management of pediatric sepsis. Pediatric heart rate has been incorporated into early warning systems and studied as a predictor for critical illness. We aim to review: (I) the role of heart rate in pediatric warning systems and (II) the role of heart rate variability (HRV) in adult and neonatal sepsis, with a focus on its potential applications in pediatrics. We conducted a literature search for papers published up to December 2019 on the utility of heart rate and HRV analysis in the diagnosis and management of sepsis, using four medical databases: PubMed, Google Scholar, EMBASE and Web of Science. This review demonstrates that the clinical utility of pediatric heart rate in predicting clinical deterioration is limited by the lack of consensus among warning systems, consensus-based guidelines, and evidence-based studies as to what constitutes abnormal heart rate in the pediatric age group. Current studies demonstrate that abnormal heart rate itself does not adequately discriminate children with sepsis from those without. HRV analysis provides a quick and non-invasive method of assessment and can provide more information than traditional heart rate. HRV analysis has the potential to add value in identification and prognostication of adult and neonatal sepsis. With further studies to explore its role, HRV analysis has the potential to add to current tools in the diagnosis and prognosis of pediatric sepsis.
Regional Movements of Reef Manta Rays (Mobula alfredi) in Seychelles Waters

The decline in numbers of reef manta rays (Mobula alfredi) throughout their range has highlighted the need for improved information on their spatial ecology in order to design effective conservation strategies for vulnerable populations. To understand their patterns of movement in Seychelles, we used three techniques—archival pop-up satellite tags, acoustic tags, and photo-identification—and focussed on the aggregation at D’Arros Island and St. Joseph Atoll within the Amirantes Group. M. alfredi were photographed within six of the seven Island Groups of Seychelles, with 64% of individuals being resighted at least once between July 2006 and December 2019 over timeframes of 1–3,462 days (9.5 years; median = 1,018 days). Only three individuals from D’Arros Island were resighted at a second aggregation site located more than 200 km away at St. François Atoll during photo-identification surveys. Satellite-tracked M. alfredi (n = 5 tracks; maximum 180 days) remained within the boundary of the Seychelles Exclusive Economic Zone, where they spent the majority of their time (87%) in the upper 50 m of the water column in close proximity to the Amirantes Bank. The inclusion of acoustic tagging data in the models of estimated satellite-track paths significantly reduced the errors associated with the geolocation positions derived from archived light level data. The insights gained into the patterns of horizontal and vertical movements of M. alfredi using this multi-technique approach highlight the significance of D’Arros Island and St. Joseph Atoll, and the wider Amirantes Group, to M. alfredi in Seychelles, and will benefit future conservation efforts for this species within Seychelles and the broader Western Indian Ocean.
The Indo-Australian and E. Palaearctic braconine wasp genus Euurobracon (Hymenoptera: Braconidae)

An illustrated key to the females of Euurobracon is provided. Three new species and two new subspecies are described: E. interstitialis sp. nov. from Malaysia; E. denticephalus sp. nov. from Dutch New Guinea; E. latitempus sp. nov. from New Guinea; E. cephalotes sumatranus ssp. nov. from Sumatra; impossibilis curticaudis ssp. nov. from Papua New Guinea. E. quadriceps var. apicalis Roman is raised to specific status. The following new synonyms are proposed: Euurobracon maculipennis (Cameron, 1910) (= E. triplagiata (Cameron, 1900)); E. melanospilus (Cameron, 1910) (= E. yokahamae (Dalla Torre, 1898)); E. merinotoides (Enderlein, 1920) (= E. forticornis (Cameron, 1905)); E. montivagus (Cameron, 1910) (= E. cephalotes cephalotes (Smith, 1858); stat. nov.); Collastes nigropectus (Cameron, 1911) (= E. yokahamae (Dalla Torre, 1898)). Two species are excluded from Euurobracon for the first time: E. nitidulus Brues, 1922 and E. mandibularis Brues, 1924. Each species of Euurobracon is fully described.