Miracle-dz/UniFAR-FTUs huggingface dataset:
Cluster analysis identifies two cognitive profiles among offspring of patients with a major psychiatric disorder: The healthy and impaired profiles

Background: Studies have shown that patients with Schizophrenia (SZ) or Bipolar Disorder (BP) have cognitive deficits. Several studies have also reported that offspring of SZ or BP parents performed worse, on average, than non at risk offspring. However, only a minority of at risk offspring will develop SZ or BP later on. Hence, the reported deficits concerning them may represent a mixture of larger and smaller deficits which, respectively, would refer to those subjects who would eventually convert versus those who never would. The present study addresses this issue by attempting to separate the at-risk offspring into two subgroups according to their cognitive performance. Methods: Our sample was composed of 131 at risk offspring from 6 to 24 years old assessed on five cognitive domains: Processing speed, Verbal memory, Visual Memory (VISEM), Working memory, and Executive functioning. A hierarchical clustering analysis was performed on all five domains. The pseudo F statistics and Pseudo T square-index were used to estimate the number of clusters. Then each cluster found was compared to a matched sample of 131 healthy control subjects using a two way ANOVA. Results: Two clusters were revealed: a cluster of at risk offspring that showed a cognitive profile almost identical to that of control subjects, and another cluster that performed much worse than the healthy controls with effect sizes often exceeding those previously seen in the literature, and reaching 2.3 for VISEM. Conclusion: To our knowledge, this is the first study highlighting a very healthy cognitive performance for a subset of at risk offspring, but a worse than known performance in the remaining offspring. Still, further longitudinal studies are needed to investigate whether these findings are associated with the transition to a major psychiatric disorder such as SZ or BP.
Principles and Practice of Isokinetics in Sports Medicine and Rehabilitation

The book begins with a simple definitions page. This is followed by a flow chart titled “How to advise the climacteric woman: the chain of reasoning. ” On the opposite page the relevant issues are detailed, together with page numbers indicating where these issues are dealt with in the book. It is a very effective way of setting out the book. Sections I and II discuss the indications for treatment. This is followed by section III, which deals with the contraindications and risks of HRT. The rest of the book, titled “Guidelines for practical HRT and the management of women on HRT” is perhaps more appropriate for European countries than Hong Kong. For example, the authors recommend a mammogram for every woman starting HRT and thereafter every two years for women with a normal risk of getting breast cancer and annually for women at high risk. Similarly, there is a relatively large section on menopausal symptoms and how to manage them. The symptom profile in Hong Kong and much of Asia appears to be substantially different to those described in the book and mammography for every woman starting HRT may not be a realistic proposition in Hong Kong. Nevertheless, on the whole, the discussion is balanced and reasoned.
International Relations of Post-Hybridity: Dangers and Potentials in Non-Synthetic Cycles

Abstract The term hybridity is losing its critical potential in the study of globalization, both because no one is not hybrid anymore and because awareness of hybridity might encourage violence. Whereas hybridity initially appeared as either cosmopolitanism or post-coloniality, it has however turned into a subversive celebration of unavailing indoctrination of any orthodoxy or canon. It is also the evidence of sited subjectivity or agency, whose unique genealogy cannot be entirely subsumed by simulating the sanctioned orthodox. This paper instead advocates the emergence of post-hybridity, which is different from hybridity in its assumption of multilayeredness, memory, reconnection, and, most importantly, non-synthetic and yet cyclical historiography. It uses the example of Hong Kong, where both dialectical and cyclical modes of existence are central, to clarify post-hybridity. The paper is primarily a pedagogical reminder of, and a remedy to, the problem of the term hybridity for the teachers and students of International Relations.
How does chronic tonsillitis affects anxiety and depression

Chronic/recurrent tonsillitis is a persistent inflammation of the tonsils due to recurrent acute or subclinical infections. During acute tonsillitis, infection may persist in the fibrous tissue and cause another tonsillitis attack after days or weeks if proper antibiotic treatment is not provided for a sufficient time. Furthermore, inflammatory scrapings inside the crypts may cause subclinical infection and subsequent tonsillitis attacks (1). Generally, a diagnosis of chronic/recurrent tonsillitis is based on tonsillitis or throat pain that recurs three to four times a year and does not respond to sufficient antibiotic treatment (2). A recurrent throat pain is generally accompanied by fever, weakness, and arthralgia. Secondary foul breath (halitosis) that fills tonsil crypts may also be present (3, 4). Chronic tonsillitis is in fact an adult disease; however, it can be observed at all ages. Like any other chronic disease, tonsillitis can also trigger psychological disorders. Numerous studies on the relationship between chronic/recurrent tonsillitis in adults and psychological disorders and quality of life are available, whichcompare the quality of life of patients before and after surgery (5) or investigate the quality of life and mental health in pediatric patients (6). This study sought to understand the complex relationship between depression and anxiety and chronic/ recurrent tonsillitis in adult patients, which was probably related to various psychiatric disorders owing to its symptoms (pain, weakness, fever, and halitosis). SUMMARY Chronic/recurrent tonsillitis is a condition that affects the quality of life with symptoms such as pain, fever, halitosis, and so forth. However, the effect of this condition on depression and anxiety has not been studied. Therefore, this study aimed to investigate the complex relationship between chronic/recurrent tonsillitis and depression and anxiety in adult patients. The study included 60 female and 60 male patients and 25 healthy male and 25 healthy female controls, aged 18–40 years. The participants were made to fill out the Beck depression and anxiety inventories (BDI and BAI). Those who met the inclusion criteria were included. The averages and cutoff values of the total scores were investigated separately for males and females. For both males and females, the averages of total BDI scores (P < 0.043 and <0.035, respectively) and total BAI scores (P = 0.019 and 0.027, respectively) were significantly higher in group 2 than in group 1. This study was novel in exploring the relationship between chronic/recurrent tonsillitis and depression and anxiety in adults. The findings of this study might enhance the understanding on this subject and serve as a valuable guidance for the interested researchers.
Diabetic encephalopathy: the role of oxidative stress and inflammation in type 2 diabetes

: Type 2 diabetes mellitus (T2DM) is a heterogeneous metabolic disorder associated with an increased risk for central nervous system disorders. Diabetic encephalopathy is a relatively unknown diabetes complication, characterized by electrophysiological, structural, neurochemical, and degenerative neuronal changes that lead to cognitive functioning limitations. Besides chronic hyperglycemia and dyslipidemia, diabetic encephalopathy represents the most relevant risk factor for cognitive dysfunction, increased incidence of dementia, and consequently Alzheimer´s disease (AD), also referred to as “type 3 diabetes. ” There has been recent evidence suggesting that oxidative stress and inflammation are key pathogenic factors for T2DM, cognitive decline, and neurodegenerative diseases, including AD. Thus in this review we aim to ascertain brain mechanisms underlying the link between T2DM and AD with a focus on oxidative stress and inflammatory processes. We also intend to review the main antioxidant/anti-inflammatory therapeutic strategies targeting the brain and contributing to halt the progression from diabetic encephalopathy into AD.
Modeling the effect of economic efforts to control population pressure and conserve forestry resources

The increase in human population poses a great menace for the forestry resources. Therefore, protection and conservation of forestry resources is a challenging subject across the globe. Keeping this point in view, we propose and analyze a nonlinear mathematical model to assess the effect of economic efforts applied to control population pressure as well as to increase forestry resources by plantation on the conservation of forestry resources. The condition when one should spend more money on plantation / reducing population pressure has been obtained. Numerical simulation is also performed to support analytical findings and identify the important parameters useful for the conservation of forestry resources.
Imbalanced Learning for RR Lyrae Stars Based on SDSS and GALEX Databases

We apply machine learning and Convex-Hull algorithms to separate RR Lyrae stars from other stars like main-sequence stars, white dwarf stars, carbon stars, CVs, and carbon-lines stars, based on the Sloan Digital Sky Survey and Galaxy Evolution Explorer (GALEX). In low-dimensional spaces, the Convex-Hull algorithm is applied to select RR Lyrae stars. Given different input patterns of (u − g, g − r), (g − r, r − i), (r − i, i − z), (u − g, g − r, r − i), (g − r, r − i, i − z), (u − g, g − r, i − z), and (u − g, r − i, i − z), different convex hulls can be built for RR Lyrae stars. Comparing the performance of different input patterns, u − g, g − r, i − z is the best input pattern. For this input pattern, the efficiency (the fraction of true RR Lyrae stars in the predicted RR Lyrae sample) is 4.2% with a completeness (the fraction of recovered RR Lyrae stars in the whole RR Lyrae sample) of 100%, increases to 9.9% with 97% completeness and to 16.1% with 53% completeness by removing some outliers. In high-dimensional spaces, machine learning algorithms are used with input patterns (u − g, g − r, r − i, i − z), (u − g, g − r, r − i, i − z, r), (NUV − u, u − g, g − r, r − i, i − z), and (NUV − u, u − g, g − r, r − i, i − z, r). RR Lyrae stars, which belong to the class of interest in our paper, are rare compared to other stars. For the highly imbalanced data, cost-sensitive Support Vector Machine, cost-sensitive Random Forest, and Fast Boxes is used. The results show that information from GALEX is helpful for identifying RR Lyrae stars, and Fast Boxes is the best performer on the skewed data in our case.
Association between SNPs of Circulating Vascular Endothelial Growth Factor Levels, Hypercholesterolemia and Metabolic Syndrome

Background and Objectives: Four single nucleotide polymorphisms (SNPs); rs6921438 and rs4416670 in LOC100132354-C6orf223, rs6993770 in ZFPM2, and rs10738760 in VLDLR-KCNV2 were reported to explain up to 50% of the heritability of vascular endothelial growth factor circulating levels. These SNPs were also studied for possible associations with circulating lipid levels in supposedly healthy European individuals and in a limited number of Iranian individuals with metabolic syndrome. To go further, the association of those four SNPs with plasma lipid parameters, hypercholesterolemia and metabolic syndrome (MetS) was assessed. Materials and Methods: A cross-sectional study was conducted on 460 individuals chosen from the general population. Demographic and clinical data were collected and DNA was extracted and genotyped using Kompetitive allele specific PCR (KASP™). A meta-analysis followed, combining our participants with the Iranian individuals (n = 336). Results: Whereas rs10738760 was associated with total cholesterol (Tchol) (p = 0.01), rs6993770 showed significant associations with both Tchol and low-density lipoprotein cholesterol (LDL-C) levels (p = 0.007 and p = 0.01 respectively). Using a multivariate logistic regression model adjusted for different confounding factors, we found that rs6993770 was associated with hypercholesterolemia, specifically high Tchol (p = 0.01) and LDL-C levels (p = 0.01). Furthermore, rs10738760 was positively associated with the risk of MetS in these individuals (p = 0.02) and in the meta-analysis (OR = 1.67, p = 0.01). Conclusion: Our results suggest that whereas rs6993770 in ZFPM2 was positively associated with hypercholesterolemia, rs10738760 (VLDLR-KCNV2) has a possible implication in MetS in two Middle Eastern populations.
Systematic condition of Psilotum ( Singh et al . , 2003 ) Class : Psilotopsida Order : Psilotales Family : Psilotaceae Genus : Psilotum Sporophytical generation of Psilotum :

Psilotum nudum L. , is of considerable importance in palaeobotany considering its age of evolution i.e. Devonian. It has also been recognized as a medicinal herb. In 2003, one sample of this species was identified just by morphological research and introduced as a new record. This research aims at introducing other samples discovered through other anatomical research besides morphology. P. nudum grows on the trunks of old trees of Alnus glutinosa (L.) Gaertn. , in the form of epiphyte, as suspended, in North Iran. The plant is 30 cm long and aerial shoot has dichotomic branches. There are prominent longitudinal lines, tiny scaly leaves with spiral phyllotaxy and bifid bracts of synangia on aerial shoot. Synangia are configured spirally on the stem and each contains three connected sporangia. Stele in P. nudum L. , is protostele. In rhizome it is of actinostele type. However, it is of siphonostele type in aerial shoot.
A Series-Fed Linear Substrate-Integrated Dielectric Resonator Antenna Array for Millimeter-Wave Applications

A series-fed linear substrate-integrated dielectric resonator antenna array (SIDRAA) is presented for millimeter-wave applications, in which the substrate-integrated dielectric resonator antenna (SIDRA) elements and the feeding structure can be codesigned and fabricated using the same planar process. A prototype 4 × 1 SIDRAA is designed at Ka-band and fabricated with a two-layer printed circuit board (PCB) technology. Four SIDRAs are implemented in the Rogers RT6010 substrate using the perforation technique and fed by a compact substrate-integrated waveguide (SIW) through four longitudinal coupling slots within the Rogers RT5880 substrate. The return loss, radiation patterns, and antenna gain were experimentally studied, and good agreement between the measured and simulated results is observed. The SIDRAA example provides a bandwidth of about 10% around 34.5 GHz for 10 dB return loss and stable broadside radiation patterns with the peak gain of 10.5–11.5 dBi across the band.
Impact of Customer Relationship Management on Brand Equity: Private Hospitals in Jaffna

The primary aim of the study is to find out the impact of customer relationship management on brand equity private hospitals in Jaffna city, Sri Lanka. The study was carried out independent sample t- test, one way ANOVA (f- test) and multiple regressions to test the operational hypotheses. The survey method used in this study is a questionnaire and a total of 127 usable responses were obtained using convenience sampling technique. Finding reveled that, Customer relationship management has impact on brand equity, and there is a significant mean different in brand equity between male and female consumers. Further the researcher suggested that, private hospitals administration bodies should have to acquire skills and knowledgeable employees in the hospitals, of action plans, providing quality of services based on humanity, and consider the organizational structure. This study would hopefully benefit to the new business makers of Jaffna as well as Sri Lanka. Key words: Brand Equity and Customer Relationship Management.
Critical level interaction of a gravity wave with background winds driven by a large-scale wave perturbation

[1] As part of the Maui-Mesosphere and Lower Thermosphere program, data from the Utah State University Mesospheric Temperature Mapper (MTM) and the University of Illinois Meteor Wind Radar (MWR) have been used to investigate wave-driven dynamical interactions in the upper mesosphere at low latitudes. On 29 June 2003, short-period (∼20 min) gravity waves (GWs) were imaged in the MTM in the near-infrared OH and O2 airglow emissions for most of the night from 0700 to 1500 UT. The GWs were observed to disappear rapidly in the O2 data (peak altitude: ∼94 km) around 1400 UT but remained evident in the lower altitudes OH data (∼87 km) for a further 30 min. Coincident background wind variations measured by the MWR suggest that the GW disappearance at the O2 layer was most probably caused by a critical level (CL) interaction. However, at the OH layer, the GW fading may also have been due to wave saturation and instabilities. During this period (1400−1500 UT), no significant change in OH and O2 rotational temperatures were measured by the MTM; however, the background winds centered on the airglow layers were observed to increase by ∼10 m/s. The background wind acceleration from the disappearing gravity waves estimated from the airglow observations was larger below the CL than at the CL, consistent with the wind variation observed by the MWR.
CoSummary: adaptive fast-forwarding for surgical videos by detecting collaborative scenes using hand regions and gaze positions

This paper presents CoSummary, an adaptive video fast-forwarding technique for browsing surgical videos recorded by wearable cameras. Current wearable technologies allow us to record complex surgical skills, however, an efficient browsing technique for these videos is not well established. In order to assist browsing surgical videos, our study focuses on adaptively changing playback speeds through the learning and detecting collaborative scenes based on surgeon hand placement and gaze information. Our evaluation shows that the proposed method is able to highlight important collaborative scenes and skip less important scenes during surgical procedures. We have also performed a subjective study with surgeons in order to have professional feedback. The results confirmed the effectiveness of the proposed method in comparison to uniform video fast-forwarding.
Signifi cance of tagI and mfd genes in the virulence of non-typeable Haemophilus infl uenzae

Non-typeable Haemophilus infl uenzae (NTHi) is an opportunist pathogen well adapted to the human upper respiratory tract and responsible for many respiratory diseases. In the human airway, NTHi is exposed to pollutants, such as alkylating agents, that damage its DNA. In this study, we examined the signifi cance of genes involved in the repair of DNA alkylation damage in NTHi virulence. Two knockout mutants, tagI and mfd, encoding N3methyladenine-DNA glycosylase I and the key protein involved in transcription-coupled repair, respectively, were constructed and their virulence in a BALB/c mice model was examined. This work shows that N3-methyladenine-DNA glycosylase I is constitutively expressed in NTHi and that it is relevant for its virulence. [Int Microbiol 2014; 17(3):159-164]
An in vivo fluorescence method for the continuous in situ estimation of phytoplankton photosynthetic characteristics

This study proposes a simple method to continuously measure, in situ, an in vivo fluorescence characteristic of a natural phytoplankton population, using 2 flow-through fluorometers and a strong light source. By this method, phytoplankton fluorescence before (F,) and after (F,) strong illumination (2250 ~ E i n m-2 S') was measured simultaneously with parameters of the photosynthesis vs irradiance curves. Data from 3 depths in the mixed layer, at 3 stations in the St. Lawrence Estuary, showed a strong relation between the ratio FA/FB and the photosynthetic parameters aB, Pi,,, I, and I,. The relation was particularly good with I, and I,, 2 possible indices of physiological adaptation. These results suggest that the ratio F,/FB can be used as an instantaneous in vivo index of photosynthetic characteristics. This simple measurement might prove useful for continuous spatio-temporal investigations of phytoplankton responses to their light environment in the water column.
Space time distribution of afterslip following the 2003 Tokachi‐oki earthquake: Implications for variations in fault zone frictional properties

GPS time series following the September 25, 2003 (UT) Tokachi‐oki earthquake (MW ∼ 8.0) reveal significant deformation. We use the Network Inversion Filter to invert for the spatial and temporal evolution of afterslip in the 30 days following the earthquake. Afterslip is concentrated adjacent to the coseismic rupture zone, between the 2003 rupture and the inferred source regions of the 1968 Tokachi‐oki and the 1973 Nemuro‐oki earthquakes. The inversion shows a rapid decay of slip‐rate in the 2003 rupture zone, with slower deceleration in the surrounding regions. The stress‐velocity paths for the afterslip regions approximately follow dτ/d ln(v) ∼ 0.6 MPa, suggestive of steady‐state velocity strengthening friction. The complementary spatial pattern of coseismic rupture and afterslip may indicate along strike spatial variations of frictional properties, although other interpretations can not be ruled out.
THE I FLUE CE OF COATI G FABRICATIO PROCESSES O THE OPTICAL EFFICIE CY OF REPLICATED MOIRÉ DIFFRACTIO GRATI GS

One of the most important parameters in the study of diffraction gratings is their optical efficiency. This paper analyzes the different manufacturing processes to cover gratings of Moiré interferometry and their influence on the quality and absolute efficiency of replicated gratings on the surfaces of specimens. The Moiré interferometry is a field measurement technique that has been used in many different fields such as applied mechanics, microelectronics, biomechanics or micromechanics, hence the importance of this study. The applied reflected coating was done by sputtering and aluminium vaporization processes. In this work different materials and thickness layers were analyzed. The obtained coatings have a high degree of reflectivity on the replicated gratings.
LpBRI1 polymorphism association with flag leaf architecture in perennial ryegrass

In order to evaluate association between sequence polymorphism in candidate genes and phenotypic traits in perennial ryegrass (Lolium perenne L.), mapping population, consisting of 96 genotypes, was assessed for traits related to seed yield with four replications over two years. The traits flag leaf length and width, inflorescence length, spikelet number, seed weight per plant, seed weight per inflorescence, 1000 seed weight and heading date revealed heritability ranging from 0.14 to 0.84 and considerable amount of variation. Marker-trait associations were studied between sequence polymorphism of five candidate genes LpIAA1, LpRUB1, LpBRI1, LpSHOOT1 and LpTB1 with putative function in plant architecture and phenotypic traits. Thirteen marker-trait associations were identified in total. Relation between 3 bp INDEL polymorphism in 3’UTR region of LpBRI1 gene and flag leaf width was confirmed in two consecutive years of field experiment. The possible regulatory role of the identified