Miracle-dz/UniFAR-FTUs huggingface dataset:
Development andValidation of a New, Simple-HPLC Method for Simultaneous Determination ofSofosbuvir, Daclatasvir and Ribavirin in Tablet Dosage Form

A sensitive, simple, selective and accurate HPLC method was developed and validated for Simultaneousanalysis of antiviral drugs,Sofosbuvir, Daclatasvir and Ribavirinthat allowreduction in treatment duration for HCV patients that in turn decrease the cost of the treatment. The chromatographic separation achieved by isocratic elution on a reversed-phase analytical column [Hypersilgold® C18 (10μm, 150 x 4.6 mm) column] at ambient temperature. The mobile phase was a mixture of Methanol, Waterand Acetonitrile in ratio of 25:30:45 (v/v/v), injection volume was 20μl. and flow rate was 1ml/ minute, detectionwavelength was 243nm. The developed method was validated as per ICH guidelines; it was precise, accurate and robust. The calibration curves of the three drugswere linear in range:5-150μg/ml for Ribavirin, 25-300 μg/ml forSofosbuvir, and 1-100μg/ml for Daclatasvir,with a correlation coefficient ≥0.999. The validated method was helpful for rapid routine analysis as the run time was less than 7 minute; theretention time was 2.007, 3.632 and 6.922 minute and LOD 0.2, 1, 0.3 μg/ml and LOQ 0.5, 3, 0.9 μg/mlfor Ribavirin, Sofosbuvir, and Daclatasvir, respectively. The method was successfully applied to analysis of Ribavirin, Sofosbuvir, and Daclatasvir in tablet dosage form with accepted % recovery for each one.
Price Adjustment to Exchange Rates and Forward‐Looking Exporters: Evidence from USA–China Trade

This paper shows that the pricing behavior of exporting firms exhibits a “forward‐looking” nature with sticky prices. As a result, the expectations of future exchange rates affect current prices at both the product level and firm level. We find evidence by employing both highly disaggregated Harmonized System (HS) 10‐digit product‐level import data of the USA and firm–product level customs data on China's exports to the USA. These findings provide evidence for a previously unexplored micro‐level forward‐looking nature of trade price adjustment as response to future exchange rates, and suggest a potentially important factor in helping explain incomplete exchange rate pass‐through.
Current trends and future directions in the practice of high-level data modeling: An empirical study

Research into the role of identity in organizations has become increasingly popular in recent years. Scholars from different organizational and management disciplines have applied the concept to address a wide variety of issues. In light of the concept’s broad applicability, we conduct a review of six prominent IS journals to examine the extent of the concept’s use in our field. Our review reveals that the concept is scantly employed by IS researchers, which, we believe, constitutes a missed opportunity. In light of this finding, we outline possible directions and opportunities for using the identity concept in IS research with the aim of enriching and diversifying the conceptual discourse in
Acceleration of the Boundary Element Method for arbitrary shapes with the Fast Fourier Transformation

This work illustrates the possibility to apply the Fast Fourier Transformation to obtain the integrals of the Boundary Element Method (BEM) on arbitrary shapes. The procedure is inspired by the technique used with great success within the framework of the half-space approximation in contact mechanics. There, the boundary integral equations are given by simple convolutions over the boundary surface. For arbitrary shapes this is not the case. Thus, the FFT and the great reduction in computational complexity that comes with it cannot be utilized as easily. In this work, it is illustrated that although the integral equations of the BEM are not convolutions over boundary of arbitrary shapes, they are indeed convolutions over the space which is one dimension higher than that of the boundary. Therefore, the FFT can indeed be used to calculate the BEM integral equations on arbitrary shapes, only this comes at the cost of increasing the dimension of the FFT. A small example is given which illustrates how the concept can be used to fully solve a BEM problem with a given closed boundary using only the FFT approach to obtain the integral equations and no hybrid techniques or other approximations.
Discontinuous Galerkin method for the spherically reduced Baumgarte-Shapiro-Shibata-Nakamura system with second-order operators

We present a high-order accurate discontinuous Galerkin method for evolving the spherically reduced Baumgarte-Shapiro-Shibata-Nakamura (BSSN) system expressed in terms of second-order spatial operators. Our multidomain method achieves global spectral accuracy and longtime stability on short computational domains. We discuss in detail both our scheme for the BSSN system and its implementation. After a theoretical and computational verification of the proposed scheme, we conclude with a brief discussion of issues likely to arise when one considers the full BSSN system.
B-cell chronic lymphocytic leukaemia in an African lion (Panthera leo)

A 15-year-old female African lion (Panthera leo) maintained at the Zoological Garden of Pistoia, Tuscany (Italy), showed signs of malaise, dyspnoea, tremors, pale mucous membranes and ataxia for two days prior to death. Complete blood count showed anaemia, thrombocytopaenia and severe lymphocytosis. At autopsy, the most relevant finding was severe, generalised splenomegaly. Histologically, high numbers of neoplastic lymphocytes diffusely infiltrated the spleen, liver, heart, pancreas, kidney and lungs. The lymphoid cells were positive for CD79a and negative for CD3 on immunohistochemistry. The histologic features of the neoplastic cells and their immunophenotype are consistent with B-cell lymphocytes. Based on surface membrane co-expression of immunoglobulin M and immunoglobulin D in most neoplastic cells, which indicated that they were naïve, antigen-inexperienced and mature circulating resting B-cells, and consistent with their appearance as small lymphocytes with high nuclear-to-cytoplasmic ratios, a diagnosis of B-cell chronic lymphocytic leukaemia was made.
Scaffolding in Teacher-Student Interaction: A Case Study in Two Oral English Classes in China

Abstract This paper reports a case study designed to understand classroom interactional processes in a Chinese university. The case study focuses on scaffolding in teacher-student interaction as well as the process of shifting the responsibility from the teacher to student. Our first aim was to determine how teacher-student interactions in two oral English classes were distributed, and our second aim was to determine how the two teachers perceive their roles in teacher-student interaction and how their perceptive differences were reflected in teacher-student interaction in their oral English classes. The data were collected through videotaping and an interview. Results show that distribution patterns of teacher-student interactions were mainly different in the two oral English classes, and the role perception differences of the two teachers were partly reflected in their teacher-student interaction. The study suggests that the process of shifting the responsibility from teacher to student is a complex process which demands great efforts from teachers as well as willingness from students. 本文围绕我国大学英语口语课堂教师和学生的互动话语，从社会文化的角度考查两个大学英语口语课堂支架式的师生互动话语的分布特点，以及这些特点与教师角色之间的关系。 研究采用课堂录像和教师访谈的方法来采集数据，并对数据进行了分析。 研究分析表明两个口语课堂的师生互动话语的分布特点以差异为主，教师在互动过程的角色与这些差异有部分的联系。 文章指出教师通过调整自己的话语来帮助学生理解并参与课堂交际是一个复杂的过程。
BACTERIAL FORAGING TECHNIQUES FOR SOLVING EKF-BASED SLAM PROBLEMS

The present paper proposes a successful application of bacterial foraging strategies to improve the quality of solutions that extended Kalman filters (EKFs) can offer to solve simultaneous localization and mapping (SLAM) problems for mobile robots and autonomous vehicles. The system can be especially useful in those situations where an incorrect knowledge of Q and R matrices of EKF can significantly degrade the SLAM performance. A fuzzy system has been implemented to adapt the R matrix of the EKF online, in order to improve its performance. The determination of the free parameters of the fuzzy system is configured as a high- dimensional metaheuristic optimization problem and E. coli bacterial swarm foraging has been successfully implemented to solve this optimization problem ofline. The utility of the proposed system is aptly demonstrated by solving the SLAM problem for a mobile robot with varying landmarks and with wrong knowledge of sensor statistics. The proposed system could demonstrate enhanced performance in comparison with usual EKF-based systems for identical environment situations. Copyright © 2002 USTARTH
Visual Knowledge Transfer Using Semantic Relatedness

Recognition of object classes has advanced to master difficult scenarios such as background clutter or multiple objects per image. Scaling to large numbers of classes, however, remains a challenge for state-of-the-art recognition approaches. In order to exploit similarities between classes, knowledge transfer between classes has been advocated. In this paper we examine the special case of transferring knowledge from known to unseen classes (zero-shot recognition). In previous work the decision which knowledge to transfer has been provided mostly by supervision in the form of manual associations between known and unseen classes or a few training examples, limiting the scalability of these approaches. We promote semantic relatedness to replace supervision in order to provide the missing link between the sources (known classes) and targets (unseen classes) of knowledge transfer. We provide a rigorous experimental evaluation of several state-of-the-art semantic relatedness measures and language resources which we evaluate on the challenging Animals with Attributes image dataset. This extensive evaluation provides insights into the different qualities and applicability of the different measures and resources.
Inspiration and Perspiration Factors in Economic Growth: The Former Soviet Union Area versus China (ca.1920-2010)

In this paper we extend our previous studies (Didenko et al., 2012; FA¶ldvAiri et al., 2012; Van Leeuwen et al., 2011) on the role of conventional factors of production (fixed, or physical, and human forms of capital) and their productivity depending on their interrelations and economic development policies. Methodologically based on Solow (1956, 1957) and Mankiw, Romer, and Weil (1992) we apply our theoretical models on the factors of economic growth to compare China with the republics of the former Soviet Union and, to this end, create a new database for both regions. Following Krugman (1994), we decompose economic growth in perspiration (i.e. production factors) and inspiration (i.e. TFP, which consists in turn of technical efficiency of the production factors and a general production frontier) factors and find that in the socialist central-planning period economic growth was largely driven by physical and, to lesser extent, human capital accumulation. Moreover, at these times conventional TFP change was strongly negative (1930s for the FSU, 1950s for China). This means that focusing mainly on physical capital increases the factors of production (hence increasing growth via perspiration) but reduces the technical efficiency of the factors of production strongly (hence lowers the growth via TFP, i.e. inspiration). After the economic transitions were launched (end 1970s in China and end 1980s in the FSU) the inspiration/perspiration pattern changed. China managed to keep technical inefficiency relatively moderate, largely by massively increasing its human capital (which made it easier to make use of physical capital). At the same time, they managed to increase their productivity frontier. In the FSU, however, the change in the human to physical capital ratio was primarily caused not by an increase of human-, but rather by a decrease of physical capital. This means that, even though technical efficiency relatively increased, the general productivity frontier remained stable or declined. This changed in the late 1990s and the start of the 21th century when the FSU started to recover somewhat, only to reach the 1990 level.
Efﬁcient Synchronization-Free Work Stealing

Work stealing is a classic algorithm for scheduling parallel computations on parallel/multicore computers. Due to its many desirable properties, work stealing is used widely in practice, especially in shared memory systems. All known shared-memory implementations of work stealing rely on synchronization primitives to enable safe distribution of parallel tasks among parallel processors. We describe a synchronization-free work-stealing algorithm for shared-memory systems. Our algorithm can be used to execute any computation DAG and has the same observable behavior as the traditional work-stealing algorithm but requires no expensive synchronization primitives (e.g., memory fences, compare-and-swap, fetch-and-add instructions). We provide a prototype implementation of the algo-rithm and perform an experimental evaluation with several benchmarks. Experiments show that the algorithm remains competitive with or improve over the traditional work-stealing algorithm.
Changes in the Use of Precision Farming Information Sources Among Cotton Farmers and Implications for Extension

Using information from precision farmer surveys conducted in the southern United States in 2005 and 2013, we evaluated changes in the use of precision farming information sources among cotton producers. Although Extension remains an important source for producers interested in precision farming information, the percentage of cotton producers using Extension to obtain precision farming information has decreased over time. Results from our study should motivate Extension professionals to re-evaluate the precision farming information they provide to producers and the practices they use to provide such information in efforts to maintain Extension's importance as an information source.
Demand driven innovation in material planning and control: A review of early implementations

INTRODUCTION Demand-driven materials planning and control represents a significant and welldeveloped alternative to the traditional approach to MRP/DRP that is embedded within today’s leading ERP systems. The term ‘Demand-driven’ emerged from the ERP company PeopleSoft in 2002 (Ptak and Smith, 2011). It has been developed upon principles to be found in other supply chain approaches, including Lean/JIT, the Theory of Constraints (TOC) and Factory Physics, and is now promoted by the Demand Driven Institute (DDI). The rationale and principles of Demand-driven have been thoroughly articulated by Ptak and Smith (2011) in a book which positions the approach in the context of MRP evolution, drawing heavily on the concepts established by the American Production and Inventory Control Society (APICS). The approach is rapidly gaining ground as a result of dissemination via professional bodies, including the UK’s Institute of Operations Management (see Harding and Ptak, 2012), and via the qualification ‘Certified Demand-driven Planner’, accredited by the International Supply Chain Educational Alliance (ISCEA). Although the concept of the ‘demand driven supply chain’ has been explored by academics (see for example Mendes, 2011), the DDI’s approach has not, so far, been covered within the academic literature. There are currently around 50 implementations of Demand-driven worldwide (that can be identified from public domain sources), and that number is rapidly growing. In order to understand the likely trajectory of Demand-driven and, to help inform practitioners of its potential benefits and likely implementation challenges, this paper will report on qualitative research into Demand-driven adoption and implementation.
Solar Kinetic Energy and Cross Helicity Spectra

We develop a formalism that treats the calculation of solar kinetic energy and cross helicity spectra in an equal manner to that of magnetic energy and helicity spectra. The magnetic helicity spectrum is shown to be equal to the vertical part of the current helicity spectrum divided by the square of the wavenumber. For the cross helicity, we apply the recently developed two-scale approach globally over an entire active region to account for the sign change between the two polarities. Using vector magnetograms and Dopplergrams of NOAA 11158 and 12266, we show that kinetic and magnetic energy spectra have similar slopes at intermediate wavenumbers, where the contribution from the granulation velocity has been removed. At wavenumbers around , the magnetic helicity is found to be close to its maximal value. The cross helicity spectra are found to be within about 10% of the maximum possible value. Using the two-scale method for NOAA 12266, the global cross helicity spectrum is found to be particularly steep, similarly to what has previously been found in theoretical models of spot generation. In the quiet Sun, by comparison, the cross helicity spectrum is found to be small.
The Use of Optimisation in the Calibration of Building Simulation Models

In this paper, a model-assisted calibration is proposed in order to reduce performance gap of simulation models, being the estimated differences between the predicted performance of the simulation model and the actual performance of the building. We use the nearly unbiased �� Nearest Neighbour (KNN) algorithm to classify the solution that exhibits the minimum performance gap based on a set of reference points. Density avoidance algorithm is used to further refine the solutions by finding regions in the space of input factors for which the model output is either maximum or minimum to meet optimum criterion, hence fine tuning the model to establish one-to-one relationship between the simulated and actual performance.
What makes a good candidate? The preferences of HR Managers about new graduated job-seekers

Information regarding skills that foster employability of University graduates is of particular interest in Italy, where youth unemployment remains high in spite of an increase of tertiary education enrolment. This paper analyzes a survey of human resource managers’ preferred job-seeker characteristics. A conjoint analysis of hypothetical new-graduated job seeker ratings indicates that English language skills, final degree grade, and work experience are the most important attributes of candidate profiles. Age reduces the attractiveness of a candidate, while the difference in preferences between laurea triennale and laurea magistrale is so small as to be offset by two years of work experience. Interactions between firm and vacancy characteristics indicate that gender preferences depend on features of specific jobs.
Impact of Heavy Traffic Beyond Communication Range in Multi-Hops Ad-Hoc Networks

For commercial availability reasons, most actual multi-hops ad-hoc simulations and test-beds are based on IEEE 802.11 standard [1] and its medium access method CSMA/CA. But this standard has not been designed for that kind of network and presents serious flaws in this context. In this paper, we shall try to highlight problems that can appear in the non-direct neighborhood of important data flows in ad-hoc networks. In some situations, the fairness of the medium access can indeed be very poor. Various techniques could be used to solve this problem. In this paper we present one solution, which only requires minor modifications to the standard.
Magnetohydrodynamic Nanofluid Natural Convection in a Cavity under Thermal Radiation and Shape Factor of Nanoparticles Impacts: A Numerical Study Using CVFEM

In this study, the natural convection of a magnetohydrodynamic nanofluid in an enclosure under the effects of thermal radiation and the shape factor of nanoparticles was analyzed numerically using the control-volume-based finite element method (CVFEM). Columns, spheres, and lamina are examples of the nanoparticle shapes used in the investigation. The study of nanofluid flow and heat transfer was accomplished with an extensive range of nanofluid volume fractions, radiation parameters, Hartmann numbers, Rayleigh numbers, and nanoparticle shape factors. Also, the correlation between the average Nusselt number and the influencing parameters of the current study was determined. The findings demonstrate that laminar nanoparticles have a more notable impact on the average and local Nusselt numbers than the other nanoparticle shapes.
Humidity influence on switching-impulse breakdown voltage of air gaps for indoor high-voltage installations

For inhomogeneous fields like in many practical insulation configurations, the switching-impulse breakdown voltage of a given air-gap usually decreases with the decrease of atmospheric humidity. A correction procedure recommended by IEC is commonly used for converting the measured voltage or the test voltage from non-standard to standard reference atmosphere, or vice versa. The applicability of the humidity correction on relative uniform gap is not clear. In this paper results from newly performed laboratory test on air gaps of different uniformity under different atmosphere are presented. Comparison is made between the outcomes of the IEC recommended corrections for these results.
Regeneration of Plantlets from Rhizome Bud Explants of Lasia spinosa (Lour.) Thwaites- A Medicinal Plants of Assam

ABASTRACT In numerable medicinal plants are commercially propagated through tissue culture for large production of elite material (Rhizome buds of Lasia spinosa {Lour.}). Thwaites could be induced on Murashige and Skoog (MS) medium supplemented with different concentrations and combinations of kinetin (kin) and 6-benzyl amino purine (BAP) alone and in combination with Naphthaleneacetic acid (NAA). Lasia is one of the traditionally important plants of Assam, which is employed in the treatment of gastrointestinal diseases, respiratory diseases and skin infections. This plant is also a rich source of dietary fibers, reported containing polyphenols, ascorbic acid and hydrocyanic acid. The present study aimed to establish producible protocol for in vitro regeneration of Lasia spinosa using rhizome bud explants. For shoot proliferation, among the various concentrations, 3.0 mgL BAP showed the highest shoot regeneration frequency of 88.2±2.8%. The highest number of shoot were recorded as 1.9 ± 0.45 in L. spinosa, but the highest shoot length (4.5±0.07 cm) was observed at reduced concentration of BAP (1.0 mgL). Plantlets rooted in 1⁄2 strength MS medium augmented with 0.1–1.0 mgL either NAA or IBA for L. spinosa for root formation. The highest percentage (79.5±2.6%), maximum number of rootlets/ shoot let (4.0±0.46) and mean length of rootlets (3.25±0.06 cm) were observed in L. spinosa. Our findings have paved a way for future investigation on another mode of regeneration like haploid production, anther culture etc and also for the commercial and rapid propagation of L. spinosa.