Miracle-dz/UniFAR-FTUs huggingface dataset:
In Situ Quantitative Tensile Testing of Antigorite in a Transmission Electron Microscope

The determination of the mechanical properties of serpentinites is essential toward the understanding of the mechanics of faulting and subduction. Here we present the first in situ tensile tests on antigorite in a transmission electron microscope. A push‐to‐pull deformation device is used to perform quantitative tensile tests, during which force and displacement are measured, while the evolving microstructure is imaged with the microscope. The experiments have been performed at room temperature on 2 × 1 × 0.2 μm3 beams prepared by focused ion beam. The specimens are not single crystals despite their small sizes. Orientation mapping indicated that several grains were well oriented for plastic slip. However, no dislocation activity has been observed even though the engineering tensile stress went up to 700 MPa. We show also that antigorite does not exhibit a purely elastic‐brittle behavior since, despite the presence of defects, the specimens accumulate permanent deformation and did not fail within the elastic regime. Instead, we observe that strain localizes at grain boundaries. All observations concur to show that under these experimental conditions, grain boundary sliding is the dominant deformation mechanism. This study sheds a new light on the mechanical properties of antigorite and calls for further studies on the structure and properties of grain boundaries in antigorite and more generally in phyllosilicates.
Long-Term Health Effect of Earned Income Tax Credit

Using decades of variation in the federal and state Earned Income Tax Credit (EITC) and the Panel Study of Income Dynamics (PSID) dataset, I examine the impact of exposure to EITC expansions in utero and during childhood on health outcomes in adulthood. In order to overcome the confounding relationship between family income and health outcomes, this study uses the maximum EITC benefit as the key variable. Reduced-form estimates show that EITC expansions had a positive impact on self-reported health status and other health measurements. Specifically, a $1000 increase in the maximum EITC exposure from ages 13 to 18 corresponds with a 0.125 point increase in the reported health status during adulthood. In addition, being exposed to EITC expansions in utero increases reported health status by 0.043 point. Relative to the range of reported health of 1 to 5 and the standard deviation of 0.97, these are very small effects. Nonetheless, these health effects are consequential, associating with increases in both family income and maternal labor supply. Labor supply induced time substitution effect competes with the income enhancement, with different relative impacts at different age intervals, creating a “U-shaped" overall health consequence.
Insights into the ligand-free structure of cyclic diguanosine monophosphate I riboswitch of Vibrio cholerae using molecular dynamics simulation

Riboswitches are key cis regulatory elements present at 5’ UTRs of mRNAs. They play a critical role in gene expression regulation at transcriptional and translational level by binding selectively to specific ligands followed by conformational changes. Ligands bind to the aptamer of riboswitches and their complex structures have been solved, but ligand-free riboswitches structures are not available which is important to understand specific ligand binding mechanism. In this paper, an all atom 150 nano-second (ns) molecular dynamics (MD) simulations of cyclic diguanosine monophosphate (c-di-GMP I) riboswitch aptamer domain from Vibrio cholerae were carried out to study ligand-free c-di-GMP I riboswitch aptamer structure and the binding mechanism. The Principle component analysis, cross correlation dynamics analysis and trajectory analyses revealed that the ligand-free structure has stable conformation with folded P2, P3 and an open P1 helix which opens the ligand binding helix-join-helix while the ligand-bound structure shows less deviation and remains as closed structure compared to the ligand-free structure. The junction residues significantly showed anti-correlated motions with each other elucidating the open conformation of the ligand-free aptamer of riboswitch. The identified key residues involved in binding are A18, G20, C46, A47 and C92. Highlights The c-di-GMP I riboswitch regulates the essential genes involved in the virulence of human bacterial pathogen V. Cholera. A 150 ns molecular dynamics run was performed to find a ligand-free stable structure of c-di-GMP I riboswitch aptamer. The trajectory analysis resulted in stable conformation of ligand-free structure with folded P2, slightly open P3 and an unwind P1 helix. The atomic level analyses through cross correlation dynamics and RMSF values showed the opening of catalytic pocket and unwinding P1 helix. The identified key residues involved in binding are A18, G20, C46, A47 and C92 at the catalytic pocket.
School factors influencing implementation of child friendly programmes in public primary schools in Kangundo sub-county, Kenya

The purpose of the study was to investigate school factors influencing implementation of child-friendly programmes in public primary schools in Kangundo Sub-county, Kenya. The study was guided by five research objectives: To establish how adequacy of physical facilities, school/community linkage psycho-social teacher and provision of teaching and learning materials influenced the implementation of child friendly schools programmes while research objective five sought to assess on child centred teaching methodologies and the implementation of child friendly schools’ in Kangundo Sub County. The study was carried out by use descriptive survey design. The target population comprised of all the 68 public primary schools in Kangundo Sub-county Machakos County. The sample was 20 headteachers, 100 teachers and 364 class 7 and 8 pupils. Data was collected using questionnaires and focus group discussion and analysed by use of descriptive statistics. Findings revealed that schools had inadequate classroom, desks, water and electricity as indicated by majority of head teachers. It was also found out that physical infrastructure in the schools were inadequate as indicated by majority 15(75.0%) of head teachers and majority 58(68.2%) of teachers. Half of headteachers 10 (50.0%) and majority of teachers 54(63.5%) indicated that community involvement in the implementation of child friendly school in the school was effective. Majority 260(77.6%) of pupils disagreed that their parents were supportive in doing homework and that their community ensure they had a child friendly school. Majority 209(62.4%) of pupils agreed that their parents were concerned with their friendly environment. The scarcity of learning materials in the classrooms has been the most serious impediment of the child friendly school model. Based on the study findings, the study concluded that schools had inadequate classroom, desks, water and electricity. It was also concluded that the classrooms in the school were not adequate. It was also concluded that psycho-social and service delivery was practiced to a very great extent in the schools. The study concluded that performance was determined by the wellbeing of a child at home and in the community and that psychosocial support ensures socially and emotionally support for pupils. It was also concluded that teachers helped pupils to understand hard topics. The study recommended that an effort to be made by the school administration to change the attitudes of all members of the school community so that whatever is done is done in the best interests of the learner. Schools should implement student-centred learning process as it allows students to actively participate in discovery learning processes.
Analysis of Time-Domain Shielding Effectiveness of Enclosures Above Lossy Half-Space Using an Improved Half-Space FDTD Method

Since shielding enclosures which are widely used in electronic systems and devices are usually located close to the ground, the effect of ground reflection must be taken into account when analyzing the electromagnetic (EM) characteristics of enclosures. Consequently, the assessment of time-domain shielding effectiveness (SE) is a composite problem of the lower half-space and the enclosure above it. However, the application of existing half-space algorithms is often limited by the high computational demand and the complex half-space Green's function, which is difficult to derive and calculate. This article proposes an improved half-space finite-difference time-domain method without employing the half-space Green's function, while effectively reducing the computational memory and time. Based on this new method, the time-domain SE of enclosures above lossy half-space is analyzed; additionally, the difference between the coupling field and time-domain SE, on the one hand, and the free space and half-space, on the other hand, is discussed in detail. The numerical results show that the time-domain SE is reduced significantly owing to the reflection effect of the lower half-space. To sum up, this method provides an effective time-domain approach for the analysis of EM characteristics of objects above the complex half-space.
The Impact of Disease Status on the Outcome of High-Dose Therapy (HDT) and Autologous Stem Cell Transplantation (ASCT) for Peripheral T-Cell Lymphoma (PTCL).

The majority of patients (pts) with PTCL present with advanced stage with high-intermediate or high-risk IPI and their prognosis are poor with current standard induction chemotherapy. HDT followed by ASCT has been shown to be effective therapy for relapsed and refractory PTCL, although the outcomes of transplant varied depending upon the histologic subtype, disease status and IPI at transplant. Given the poor outcome with current treatment approach, HDT and ASCT as consolidative therapy during first remission are being investigated in pts with PTCL. We performed retrospective analysis of all pts with T-cell, NK cell and null cell lymphomas who underwent HDT and ASCT between 2/1991 to 6/2005. We analyze the outcome based on disease status at transplant and the subset of PTCL. There were 57 pts (35 male, 22 female) with a median age of 45 years (range 5–68). Histology included 6 (10.5%) angioimmunoblastic T-cell lymphoma (AILD), 26(46%) Anaplastic large cell lymphoma (ALCL), 22 (39%) PTCL, unspecified (NOS), 1 panniculitis like T-cell, 1 NK-T, and 1 adult T-cell lymphoma. Twelve (21%) were transplanted during first remission; 11 were high intermediate-high risk IPI, and 1 for histology NK-T. Twenty-eight (49%) were transplanted during relapse or ≥second remission and 17 (30% ) induction failure or primary refractory disease. Twenty-one (37%) had advanced stage III-IV at transplant. The median number of chemotherapy regimens was 2 (range 1–5). For ALCL subtype, 9 were anaplastic lymphoma kinase (ALK) positive, 9 ALK negative, 8 unknown. Results: At a median follow-up of 22 months (range 0.5–179), 29 are alive in remission, 25 relapsed and 3 died from transplant related mortality. One patient developed therapy induced myelodysplasia at two years post ASCT and is alive in remission after allogeneic stem cell transplant. The 2 years overall survival (OS) and disease-free survival (DFS) for the whole group were 53% (95% CI 46–60), and 45% (95% CI 39–50), respectively. The OS and DFS were significantly better for pts. who were transplanted in first complete remission (Figure1). The 2-year OS and DFS were both 83% (95% CI 55–94) for pts. transplanted in first remission compared to 45% (95% CI 38–52%, p=0.03) and 35% (95% CI 30–40, p= 0.006), respectively for those transplanted beyond first remission. Univariate models showed that the risk of death and/or relapse was significantly less among the pts. transplanted in first complete remission (OS, DFS and time to relapse: p Conclusion: our results suggest that HDT and ASCT can improve prognosis and survival of pts. with PTCL. The outcome of ASCT is best when performed during first complete remission. The role of HDT and ASCT during first remission should be further investigated in larger multi-center studies. In contrast to other reports, the prognosis of pts. with ALCL is similar to other PTCLs.
The Quality of Bali Beef from East Nusa Tenggara during Distribution Process from Slaughterhouse to Consumers

The aims of this study were to analyze the physicochemical quality and microbiological condition of Bali beef during distribution process from slaughterhouse to consumers. The study used six heads of Bali cattle from East Nusa Tenggara which were transported by Camara Nusantara cattle ship from East Nusa Tenggara (Kupang) to Tanjung Priok then they were slaughtered at Jatimulya slaughterhouse. Samples were taken from three points distribution: 1) at slaughterhouse, 2) at market, 3) at consumers’ freezer (beef after 3 days at consumers’ freezer). Observation on pH, water holding capacity, cooking loss and tenderness was done to measure the physicochemical quality of Bali beef. In terms of microbiology quantitative analysis of total plate count Escherichia coli, Staphylococcus aureus, and Salmonella sp were done on Bali beef. All data were analyzed statistically using two-way analysis of variance (ANOVA). The results showed that Bali beef during distribution had normal pH value ranges between 5.43 - 5.57, water holding capacity ranges between 37.1%-38.9%, tenderness ranges between 6.02-8.35 and cooking loss range between 40.26% - 49.72%. Total plate count showed that the number of Escherichia coli, Staphylococcus aureus, and Salmonella sp. contaminated the Bali beef exceeds Indonesia national standard (3932:2008). However, the physicochemical quality of the beef was in the normal range. The characteristics of Bali beef at three points above mentioned are normal pH, stable water holding capacity, high level of tenderness, and low level of cooking loss.
The Foundations of Concordance Views of Phylogeny

Despite the enormous importance and widespread use of the term, it is unclear exactly what a phylogeny is and what a phylogenetic tree represents. A natural thought is that a phylogeny should represent the “dominant history” of the flow of genetic information. Here, I will focus on methods in which a tree is determined by input gene trees. I compare various possibilities of how to do this including consensus trees, theR∗ triplet method, and concordance methods. I make precise the notion of a concordance factor and then compare concordance trees to species trees, which attempt to track population histories through time. I show that even in the most idealized circumstances, it is possible for the primary concordance tree to differ from the species tree. I argue that when these trees differ, there are reasons to think of the primary concordance tree as a better representation of phylogenetic history than the species tree and that when these highly idealized conditions break down, it is especially plausible that we should take concordance trees seriously as an interpretation of phylogeny and as the basis for taxonomic grouping.
ANALISIS SWOT UNTUK MENENTUKAN STRATEGI PENANGANAN BARANG JASA TITIP (STUDI KASUS KPU BC TIPE C SOEKARNO-HATTA)

This research aims to determine appropriate strategy conducted by KPU BC Type C Soekarno-Hatta in controlling passenger’s imported good in particularly regarding Jasa Titip (Jastip) service provided in Soekarno-Hatta International Airport due to the role of Directorate General of Customs and Excise as revenue collector and community protector. This research uses the approach of post-positivism to the type of descriptive. The data collection techniques are observation, depth interview, and literature study. This study uses SWOT Analysis. Internal and external factors are identified in the SWOT matrix. Result shows that an integrated information system connected to other authorities’ database enhanced with special feature is highly required. In addition, KPU BC Type C Soekarno-Hatta should have been initially planning the need of sophisticated NPP detection tools and X-Ray machine. The Analyst Teams should upgrade their competencies so that they are able to understand the behavior of Jastip provider in using social media. A program to educate society about import regulations, obligations, and penalties are also need to be prepared. Lastly, a new policy should immediately be made.
Role of Surface-Layer Coherent Eddies in Potential Vorticity Transport in Quasigeostrophic Turbulence Driven by Eastward Shear

The transport by materially coherent surface-layer eddies was studied in a two-layer quasigeostrophic model driven by eastward mean shear. The coherent eddies were identified by closed contours of the Lagrangian-averaged vorticity deviation obtained from Lagrangian particles advected by the flow. Attention was restricted to eastward mean flows, but a wide range of flow regimes with different bottom friction strengths, layer thickness ratios, and background potential vorticity (PV) gradients were otherwise considered. It was found that coherent eddies become more prevalent and longer-lasting as the strength of bottom drag increases and the stratification becomes more surface-intensified. The number of coherent eddies is minimal when the shear-induced PV gradient is 10–20 times the planetary PV gradient and increases for both larger and smaller values of the planetary PV gradient. These coherent eddies, with an average core radius close to the deformation radius, propagate meridionally with a preference for cyclones to propagate poleward and anticyclones to propagate equatorward. The meridional propagation preference of the coherent eddies gives rise to a systematic upgradient PV transport, which is in the opposite direction as the background PV transport and not captured by standard Lagrangian diffusivity estimates. The upgradient PV transport by coherent eddy cores is less than 15% of the total PV transport, but the PV transport by the periphery flow induced by the PV inside coherent eddies is significant and downgradient. These results clarify the distinct roles of the trapping and stirring effect of coherent eddies in PV transport in geophysical turbulence.
Motion reconstruction for optical tomography of trapped objects

Optical and acoustical trapping has been established as a tool for holding and moving microscopic particles suspended in a liquid in a contact-free and non-invasive manner. Opposed to standard microscopic imaging, where the probe is fixated, this technique allows imaging in a more natural environment. This paper provides a method for estimating the movement of a transparent particle which is maneuvered by tweezers (assuming that the inner structure of the probe is not subject to local movements) by making use of the assumption of a smooth movement in time. The mathematical formulation of the motion estimation leads to an infinitesimal version of the common line technique used in cryogenic electron microscopy single particle imaging to estimate the orientations of the particles in the probe.
MR imaging of dural sinus thrombosis: A case report

-이시경·한춘환·이문옥·박경주 We present a case of angiographically . confirmed transverse and sigmoid sinus thrombosis , image with MR , in a 20 year old male with a history of otitis media and maxillary sinusitis. T1-weighted image demonstrated an isosignal intensity mass with tubular-shaped low signal intensity in right transverse and sigmoid sinus. The thrombus had high signal intensity on T2-weighted image. The signal intensity of the thrombus on Gd-DTPA enhanced T 1-weighted image was unusually high similar to that o[ transverse sinus Although dural sinus thrombosis has a non-specific MR signal intensity , findings of MRI in this case may serve as an aid in future evaluation of venous thrombosis.
Maneuver detection and tracking of a space target based on a joint filter model

Orbit maneuver of non‐cooperative space targets is difficult to detect, and thus greatly affects the accuracy of real‐time target tracking. To solve this problem, a joint filter‐based algorithm is proposed to detect and track targets with random pulse maneuvering. In the algorithm, the joint filter is constructed using two nonlinear filters. The first is an auxiliary filter that utilizes the kinematic model to predict the target motion and estimate the target movement according to the continuity of Keplerian elements. The other is a primary filter that uses an orbit dynamic model to predict the target motion and utilize the estimated results provided as feedback by the auxiliary filter as the constraints to re‐estimate the target orbit in real time. Moreover, simulations were conducted to detect and track non‐cooperative space targets with a series of random pulse maneuvers, and thus validate the efficiency of the new algorithm.
Experimental verification of monitoring techniques for metal‐oxide surge arrester

Monitoring and diagnostics of metal-oxide surge arresters (MOSAs) have been a research topic for decades. During these years, many monitoring and diagnostic methods have been developed. However, only a few studies perform a comparative analysis of these methods with respect to their performance in different operating conditions. This study briefly explains the most commonly analysed MOSA monitoring techniques and performs a comparative analysis of these techniques on an experimental basis, considering different operating conditions of the arrester. The experimental setting is made to simulate different operating conditions regarding operating voltage root mean square value, voltage harmonics, and temperature conditions. The results show the reliability of MOSA indicators in the analysed conditions, suggesting which indicators and methods should be used for the purpose of MOSA diagnostics.
Family-centred music therapy with preterm infants and their parents in the Neonatal Intensive Care Unit (NICU) in Colombia – A mixed-methods study

ABSTRACT This article reports a mixed-methods study of Music Therapy (MT) with preterm infants and their parents in a neonatal intensive care unit (NICU) in Colombia. The aim was to find out whether live MT during kangaroo care had an effect on the physiological outcomes of the neonates and would help parents to decrease their anxiety levels and improve parent–infant bonding. The participants were 36 medically stable neonates born between the 28th and 34th week of gestation and their parents. The quantitative data collection included heart rate, oxygen saturation, weight gain, length of hospitalization and re-hospitalization rate. The assessment measures for anxiety and bonding were the State-Trait Anxiety Inventory (STAI) and the Mother-to-Infant-Bonding Scale (MIBS). Thematic analysis was used to analyse the qualitative data collected with semi-structured interviews and questionnaires. The quantitative results showed statistically significant improvements in maternal state-anxiety (p = .007) and in the babies weight gain per day during the intervention period (p = .036). Positive trends were found regarding the babies’ length of hospitalization and re-hospitalization rate. Both parents improved their scores with the MIBS, but this was not statistically significant. The qualitative analysis showed that MT was important for parental well-being, for bonding and for fostering the development of the neonates. Interacting musically with their babies helped parents to experience feelings of connectedness and to distract themselves from their difficulties and from the noisy hospital environment.