Miracle-dz/UniFAR-FTUs huggingface dataset:
CMAR_A_305946 5443..5455

1Department of Oral and Maxillofacial Surgery, The First Affiliated Hospital of Chongqing Medical University, Chongqing, 400016, People’s Republic of China; 2Department of Laboratory Medicine, The First Affiliated Hospital of Chongqing Medical University, Chongqing, 400016, People’s Republic of China; 3Key Laboratory of Diagnostic Medicine Designated by the Ministry of Education, Department of Laboratory Medicine, Chongqing Medical University, Chongqing, 400016, People’s Republic of China; 4Department of Pathology, Central Hospital of Jiangjin District, Chongqing, 402260, People’s Republic of China Introduction: Growing evidence suggests that long non-coding RNAs (lncRNAs), such as lncRNA HOXA-AS2, are critical regulators involved in human cancer. However, the biological functions and detailed mechanisms underlying how lncRNA HOXA-AS2 affects oral squamous cell carcinoma (OSCC) remain unexplored. Methods: The expression of lncRNA HOXA-AS2 and miR-567 was determined in OSCC cell lines and clinical tissues by quantitative real-time PCR (qRT-PCR). Target site prediction and luciferase report assays were used to explore their potential interaction and binding sites between lncRNA HOXA-AS2 and miR-567. Overexpression or silencing expression of lncRNA HOXA-AS2 was performed to confirm that miR-567 was suppressed by lncRNA HOXA-AS2. WST-1 assay, crystal staining assay, and cell cycle analysis were used to assess the cell viability and proliferation ability. The target gene of miR-567 was predicted by Targetscan and validated by luciferase report assay as well as qRT-PCR and Western Blot. Xenograft nude mice model was done to demonstrate that lncRNA HOXA-AS2 promoted cell proliferation via targeting miR-567/CDK8 in vivo. Results: LncRNA HOXA-AS2 was up-regulated in OSCC cells and tissues with the expression of miR-567 decreased. The tissue lncRNA HOXA-AS2 expression was found to positively correlate with the TNM stage and lymph node metastasis of OSCC patients. In terms of the mechanism, we found that lncRNA HOXA-AS2 negatively regulates miR-567 expression via a direct interaction. Functionally, overexpression of lncRNA HOXA-AS2 significantly promoted OSCC cell proliferation, while knockdown of lncRNA HOXA-AS2 significantly inhibited it. We also observed that miR-567 directly targets the 3ʹ UTR of CDK8. Moreover, silencing lncRNA HOXA-AS2 inhibited tumor growth with the expression of miR-567 increased and CDK8 decreased in vivo. Conclusion: LncRNA HOXA-AS2 was up-regulated in OSCC, and its up-regulation correlated with poor clinical outcomes. The lncRNA also promoted OSCC cell proliferation by directly binding to miR-567, leading to an increase in CDK8 expression. The potential prognostic value of lncRNA HOXA-AS2 should be explored in future studies.
Multidisciplinary research in Spain. A network perspective

This contribution presents a network approach to analyse the current situation of multidisciplinary research in Spain. To this aim, all coordinated projects funded by the Spanish Ministry of Science and Innovation in the 2013-2018 timeframe have been considered as a proxy for multidisciplinarity. The information on each institution has been complemented with its geographical location (latitude, longitude and autonomous community) as well as with its position according to the Scimago Institutions Rankings. Two networks were built: the network of the interactions between institutions and the network of thematic areas. Topological analyses were conducted on the two. Our results show that the two networks have a clear modular structure, and the role detection analyses conducted on both networks provide relevant insights into the relative importance of the different research institutions and thematic areas respectively.
Nonlinear Extended State Observer based Active Disturbance Rejection Control of a Laser Seeker System

In this paper, the laser seeker control problem is solved in the framework of active disturbance rejection control (ADRC). The considered problem, which consists of laser seeker stabilisation and target tracking, is expressed here as a regulation problem. A nonlinear extended state observer (NESO) with varying gains is used to improve the performance of linear ESO (LESO), and thus enable better control performance in both transient period and steady-state, with lower control effort. Based on a detailed analysis of system disturbances, a special ADRC tuning method is proposed. The stability of the overall control structure is analysed with a description function method. Through comparative simulations LESO-based and the introduced NESO-based ADRC for the laser seeker system, the advantages of the proposed scheme are shown.
Performance Appraisal System as Perceived by Staff Nurses and its Relation to their Commitment

Background: Performance appraisal system is developed to provide justification for career development, accountability, recognition, promotion, compensation, discipline and increase in remuneration. Performance appraisal system must be identified by staff nurses that affect their commitment. Aim of the study: Was to assess performance appraisal system as perceived by staff nurses and its relation to their commitment. Design: Descriptive correlational design was utilized to achieve the aim of present study. Setting: This study was conducted at Benha university hospital at the intensive care units. Sample: The study included all 200 staff nurses who were working at the above mentioned setting during the time of the study and have at least one year of experience in their work setting. They are distributed in the work setting. Tools: Two tools were used for data collection namely performance appraisal system questionnaire and staff nurses’ commitment questionnaire. Results: 68.0% of studied staff nurses had high perception of performance appraisal, while 56% of them had high commitment. Conclusion: There was statistically significant positive correlation between performance appraisal system and commitment among the studied staff nurses. Recommendations: Attending and participation in training programs and decision making to keep commitment level high, Continuous education to cope with changes that happen daily in nursing field and developed performance appraisal systems and continuous supervision and appraisal interview should be conducted with nurses through daily and weekly discussion by their immediate supervisors to discuss their job performance to learn more and develop their knowledge and skills. ـــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــ ـــــــــــــــــــــــــــــــ
MASIMO AS NONINVASIVE CONTINUOUS MONITORING FOR GUIDING FLUID IN INTENSIVE CARE UNIT

Background: It is necessary to keep tracks of blood and fluid treatment during admission patient in intensive care unit Patient may have signs of hypovolemic but fluid administration is not always beneficial, we are in need of bedside devices and techniques which can predict fluid responsiveness effectively and safely. The pleth variability indices (PVI) allow noninvasive assessment of fluid management. It is based on respiratory changes in arterial pulse pressure. PVI reflect vascular tone, circulating blood volume and intra thoracic pressure. Objective: To compare between PVI and CVP (central venous pressure) as effective measures to manage of fluid loading in monitorization in I.C. U. Patients and Methods: This study was carried out at King Khaled Hospital between June 2017 and October 2018 on 200 randomized patients dividing into two equal groups: Group (I) measuring fluid by CVP, and Group (II) measuring fluid by Masimo to assess fluid management therapy. Results: In comparison of fluid management in I.C. U, the amount of fluid replacement was 3500 ± 1980.2 in group (I), and 1913 ± 540 in group (II). There was no significant difference between the two groups in red blood cells transfusion or hemoglobin level. Conclusion: Masimo can be used as bedside non-invasive technique to measure fluid responsiveness in operating room and intensive care unit without complication, and more reliable than some invasive technique in guiding fluid therapy.
Perceived Usefulness of Big-Data for Store Layout: Evidence for Organized Retailers of Karachi

Big-Data is one of the most useful technologies available nowadays to understand behaviorsand patterns. However, in addition to its societal benefits technology might also be used bypractitioners in industrial settings. The Retail industry is also treated as the one which might receive major benefits from the use of Big-Data and therefore this study is purposively associated with implications of Big-Data for the retail sector. The Study uses store layout as the dependent variable as it has the most influence on purchase as the real purpose of Big-Data is to analyze behavior and patterns, therefore, the selection of variable is legitimate. However, the technology is not well-known in emerging markets like Pakistan therefore study is linked with quota sampling and uses SMART-PLS to analyze results. Results indicated that Big-Data was perceived as the potent tool for operations of the organized retail sector of Karachi.
FRAMEWORK FOR PLANNING CAPACITIES TO MAXIMIZE THE FEASIBLE RESILIENCE OF NETWORK INFRASTRUCTURE SYSTEMS

Infrastructures are connected between themselves and their connections form a complex network. Disaster impacted infrastructures have a reduced level of serviceability. The impact of the reduction of serviceability of disaster-affected infrastructures cascades through the entire infrastructure network. The recovery capacity of the network governs the recovery curve of a disaster-impacted infrastructure network system. Moreover, the speed of recovery of the infrastructure network from a post-disaster condition to the pre-disaster condition dictates the resilience of the system. Building these capacities requires spending money. The extent of resilience that can be afforded under a given budget situation is termed as the feasible resilience. This paper presents a framework for planning the capacities so that the feasible resilience of the network can be maximized under a budget situation. To achieve the said objective, the recovery time of a disaster-affected infrastructure network has been minimized. The outcome is the optimal restorative capacities the network needs to have so that the feasible resilience is maximized under a specified budget condition. The outcomes can be used by the decision-makers in natural disaster risk mitigation planning.
Populist attitudes and perceptions of public opinion and the media: A comparative correlational study between Spain and Colombia

Introduction: Populism has experienced a worrying growth in the last decade in different locations around the world. This globalizing process has been enhanced by the immediacy, interaction, and participation of social networks, cyber media, and other digital platforms. In this context, the perception that young people give to this type of phenomena constitutes a field of study of great interest for the Social Sciences. This research examines the correlations between populist attitudes, perception of public opinion, and opinions about the media in students of Communication Sciences in Colombia and Spain. Methods: Based on an exploratory-correlational approach and a quantitative design, this research has analyzed the reflections and priorities of a group of n=499 undergraduate and graduate students related to Communication Sciences in Colombia and Spain. Results: The study has confirmed the leading role played by social networks in the formation of radical opinions while detecting a decline in the influence of television among young audiences. In addition, the study establishes that the index of public opinion perception is higher in Spain, while the index of media perception or anti-elitist attitudes is higher in Colombia, and there is no clear link between populist attitudes and a political ideology of extremes. Conclusions: The correlations examined note a tendency towards disaffection and discredit towards politics in general, especially by the young population, which affects actors and institutions. It alludes to the preference of this population group for interacting and informing themselves on digital platforms and presents populist attitudes, without clear ideological identification, but with a clear tendency towards simplification of messages, thus emphasizing the need to educate the critical view of citizens and to work on media literacy as a crucial strategy against the growth and expansion of populism.
Business Objects and Components for Web-Based Information Systems Development

Global competition among today(cid:146)s enterprises forces their business processes to evolve constantly, leading to changes in corresponding Web-based information systems. Most existing approaches that extend the traditional software engineering to develop Web-based information systems are based on object-oriented methods. Such methods emphasize on modeling individual object behaviors instead of system behavior. This paper proposes the Business Process-Based Methodology (BPBM) for developing such systems by using a business process as a unified conceptual framework for analyzing relationships between a business process and associated business objects, for identifying business activities and designing object-oriented components called business components. These business components can represent more clearly semantic system behaviors than linkages of individual object behaviors. A change made to one business process impacts some encapsulated atomic components within the respective business component without affecting other parts of the system. A business component is divided into parts suitable for implementation of multi-tier Web-based information systems.
STATISTICAL EVALUATION OF SURFACE WIND METHOD FOR ELECTRIFICATION IN KEBBI STATE, NIGERIA

Africa and Nigeria in particular is blessed with abundant and constant supplies of fine, clean and sustainable mean for rural and urban electricity generation (renewable energy). Renewable energy such as solar, Hydro, Geothermal, Biomass and surface wind etc., has been found very useful in power generation to many sub-Saharan African countries with attendant significant sustainability and reliability. This study was aimed at evaluating and assessing the potentiality of surface wind in Kebbi state for possible power generation thereby mitigating the challenge of energy crisis and demands for rapidly growing population. The suitable model used for the data analysis was ARIMA (1,1,2), and statistics were checked and stationarity of the data were observed and test using Kwiatkowski Phillips, Schmidt and Shin (KPSS) test. The study area from the analysis of surface wind at 0.01%, 0.05% & 0.1% level of significances depicts well for reliability and sustainability for electricity generation in the state. The study found that surface wind due to its abundance in significant amount throughout the year all over the state with highest recorded values obtained in 2009, 2010 and 2011, if well-harnesses and utilizes it could serve as a good prospect for power generation in Kebbi state and its environs.
Enhancing The Performance of Rice-Grain Milling Machine By Attaching A Developed Primary Cleaning-Unit تحسين اداء آلة تبييض الأرز بأضافة وحدة تنظيف أولية مطورة

The present study aims to enhance the performance of the rice grain-milling machines by using an attached primary cleaning-unit. The performance of the developed rice grain-milling machine was studied in terms of four different sieve shapes “CSS” of the attached primary cleaning unit (“A”, “B”, “C” and “D”) with four different feeding rates (1.00, 1.25, 1.50 and 1.75 Mg/h) and four different primary cleaning sieve “PCS” speeds (310, 360, 420 and 470 rpm). The machine performance was depended on measuring machine productivity, machine efficiency, cleaning efficiency, total grain losses, required power, energy requirements and both operational and criterion costs. Results indicated that the best performance was yielded with the use of primary cleaning unit sieve shape “D” side by side with adjusting the feeding rate at 1.25 Mg/h and “PCS” speed at 360 rpm. Under these conditions values of machine productivity, machine and cleaning efficiencies were 1.20 Mg/h, 94.80 % and 96.90 % respectively. Meanwhile, the required power and energy requirements were 17.0 kW and 20.53kWh/Mg respectively. Finally, minimum operational and criterion costs were 43.18 and 94.52 LE/Mg, respectively.
From computational thinking to creative thinking: an analysis of their relationship in high school students

The objective of the article is to determine which dimensions of computational thinking are related to the dimensions of creative thinking. The methodology is quantitative with a descriptive non-experimental cross-sectional design. Two instruments are used: one that measures computational thinking through the Directions, Loops, Conditionals, and Functions dimensions, and another that measures creative thinking through the Originality, Fluency, Elaboration, and Flexibility dimensions. The sample was made up of N = 275 students from 7 educational institutions in the Diguillin province, Ñuble Region, Chile. The results show that computational and creative thinking are related to each other. The loops and conditional dimensions are significantly related to all the creative thinking dimensions. The creative thinking dimension elaboration is the most influenced by loops and conditionals, followed by fluidity, originality and flexibility. In conclusion, loops and conditionals are the essential dimensions for stimulating the creative thinking dimensions.
Oto-BaCTM: An Automated Artificial Intelligence (AI) Detector and Counter for Bagworm (Lepidoptera: Psychidae) Census

The bagworm species of Metisa plana, is one of the major species of leaf-eating insect pest that attack oil palm in Peninsular Malaysia. Without any treatment, this situation may cause 43% yield loss from a moderate attack. In 2020, the economic loss due to bagworm attacks was recorded at around RM 180 million. Based on this scenario, it is necessary to closely monitor the bagworm outbreak at infested areas. Accuracy and precise data collection is debatable, due to human errors. Hence, the objective of this study is to design and develop a specific machine vision that incorporates an image processing algorithm according to its functional modes. In this regard, a device, the Automated Bagworm Counter or Oto-BaCTM is the first in the world to be developed with an embedded software that is based on the use of a graphic processing unit computation and a TensorFlow/Teano library setup for the trained dataset. The technology is based on the developed deep learning with Faster Regions with Convolutional Neural Networks technique towards real time object detection. The Oto-BaCTM uses an ordinary camera. By using self-developed deep learning algorithms, a motion-tracking and false colour analysis were applied to detect and count number of living and dead larvae and pupae population per frond, respectively, corresponding to three major groups or sizes classification. Initially, in the first trial, the Oto-BaCTM has resulted in low percentages of detection accuracy for the living and dead G1 larvae (47.0% & 71.7%), G2 larvae (39.1 & 50.0%) and G3 pupae (30.1% & 20.9%). After some improvements on the training dataset, the percentages increased in the next field trial, with amounts of 40.5% and 7.0% for the living and dead G1 larvae, 40.1% and 29.2% for the living and dead G2 larvae and 47.7% and 54.6% for the living and dead pupae. The development of the ground-based device is the pioneer in the oil palm industry, in which it reduces human errors when conducting census while promoting precision agriculture practice.
ROLE OF ORGANIZATIONAL STRUCTURE ON CONSTRUCTION WASTE MANAGEMENT AMONG KUANTAN MALAYSIAN CONSTRUCTION INDUSTRIES

The construction industry is one of the sectors contributing to the Malaysian economy and is regarded as an important component of the Malaysian economy. At the same time, as the number of building projects rises, the amount of waste created by building projects also increases, which also has many negative effects on the environment and public health. To reduce the amount of waste created by construction projects, waste must be properly handled and effective practices in the management of construction waste must be implemented in all construction industries. This research paper aims to answer these problems above in order to: 1) to investigate the relationship between formalization structure and construction waste management in Pahang construction industries; and 2) to investigate the relationship between centralization structure and construction waste management in Pahang construction industries. Data were obtained from 107 respondents among construction companies in Pahang. The PLS-SEM technique was used to test both the measurement and structural models in this analysis. The outcome shows that there is an important connection between the formalization structure and the management of construction waste among the construction companies operating in Pahang. The structure of centralization and waste management for construction was also found to be positively associated in this study.
The Effect of Extrusion Voltage and Flowrate to the Viability and Survivability of Probiotic L. casei Encapsulated in Alginate-Chitosan

Chitosan-coated L. casei containing alginate capsules (shortened as L. casei capsules) were prepared by extruding L. casei containing alginate solution at different extrusion voltage and and flow rate followed by coating the wet capsules in chitosan solution. This study aimed to determine the effect of extrusion voltage and sodium alginate liquid flow rate on the viability of L. casei bacteria in the encapsulation process. The encapsulation process in this study was carried out by the extrusion method using sodium alginate of 1% (w/v) and chitosan of 0.2% (w/v). The resulted beads were immersed in a simulated gastric fluid (SGF) (NaCl 0.2%; HCl 0.5 M with a pH of 1.5) for 1, 60, and 120 min at 37 °C. The number of L. casei cells before encapsulation was 12.3 log CFU. After encapsulation, the maximum viability of L. Casei obtained by voltage variations of 0 kV and flow rate 5 mL/min were 12.26 log CFU. After testing the beads in SGF for 1 min, the results obtained indicate that viability of L.casei in the sodium alginate - chitosan beads with an extrusion voltage of 0 kV and 5 mL/min was 11.8 log CFU/g. The result indicated that encapsulated L. casei in the sodium alginate - chitosan beads with a voltage of 0 kV and 5 mL/min was the highest survivability level of 97.38 %. The conclusions of the study were The higher extrusion voltage can kill more L. casei while the higher extrusion flow rate can protect more L. casei.