Miracle-dz/UniFAR-FTUs huggingface dataset:
Economic analysis of the microgrid with multi-energy and electric vehicles

Electric vehicles (EVs) may play dual roles when they plug in a microgrid. They appear as loads during charging, meanwhile they may also be used as storage units to supply energy to the rest loads in the microgrid if the batteries have the sufficient spare energy. Considering the characteristic of bidirectional energy flow of EVs in a microgrid, this paper proposes the energy dispatch model and strategies for the microgrid including Wind generators, Photovoltaic systems, Battery storages, EVs and other local loads to analyze the impact of incorporating vehicles within and without microgrid on the economic operation of the microgrid. The simulation results indicate that incorporating EVs within the microgrid can not only minimize the capital cost of storages and reduce operation cost of the microgrid's operator, but also save the cost of EVs's owners.
Media Mediate Sentiments: Exploratory Analysis of Tweets Posted Before, During, and After the Great East Japan Earthquake

When the Great East Japan Earthquake occurred, Twitter was used as an infrastructure for sharing information carried by other media. In other words, Twitter is considered as a "meta medium. " Earthquake-related tweets included information that was of questionable veracity, contained vicious rumors, and propagated matters of controversy that often gave rise to various discussions and arguments. In this research, the authors analyzed 89,351,242 tweets posted from December 11, 2010 to April 16, 2012. They then extracted 9,816,625 URLs and classified the top 100 domains of these URLs into 19 media categories. The emotional reactions of Twitter users were investigated by counting the terms conveying positive and negative emotions included in the body of tweets along with the media URLs. The authors' findings revealed differences in terms of the frequency with which terms expressing emotions were evoked and differences in the patterns of their surges, across the various media. The authors also considered the usage of various terms appearing in tweets concurrently with the terms expressing emotion.
Youth in Angola: Keeping the pace towards modernity

Today’s Angolan youth’s experiences of life are shaped both by conflict and new hopes. This applies to those who were born and raised in rural areas – the most affected by war – as well as to urban youth, with more access to modernity but whose future is equally under permanent threat. War and uncertainty affect the way young people face the future, limiting their possibilities takeoff making decisions about their lives. Peace has brought about new opportunities but also many challenges. Based on qualitative data collected in Angola, this paper analyses the challenges young people are facing nowadays in Angola, their expectations and aspirations for the future, and how the idea of modernity is shaping them.
A Three-Megabase Yeast Artificial Chromosome Contig Spanning the C57BL Mouse Igh Locus1

The mouse Ig H chain (Igh) complex locus is composed of >100 gene segments encoding the variable, diversity, joining, and constant portions of the Ab H chain protein. To advance the characterization of this locus and to identify all the VH genes, we have isolated the entire region from C57BL/6 and C57BL/10 as a yeast artificial chromosome contig. The mouse Igh locus extends approximately three megabases and contains at least 134 VH genes classified in 15 partially interspersed families. Two non-Igh pseudogenes (Odc-rs8 and Rpl32-rs14) were localized in the distal part of the locus. This physical yeast artificial chromosome map will provide important structure and guidance for the sequencing of this large, complex, and highly repetitive locus.
Discovery of a glowing millipede in California and the gradual evolution of bioluminescence in Diplopoda

Significance The enigmatic millipede Xystocheir bistipita has been rediscovered after a half-century. The rediscovery unexpectedly reveals that the species is bioluminescent. By reconstructing its evolutionary history, we show that X. bistipita is the evolutionary sister of Motyxia, the only bioluminescent millipede genus in the order Polydesmida. We demonstrate that bioluminescence originated in the group’s common ancestor and incrementally grew brighter through evolutionary time. Luminescence in Motyxia may have initially evolved to cope with metabolic stress triggered by a hot, dry environment and was repurposed as a warning signal by species colonizing high-elevation habitats with greater predation risk. The discovery of bioluminescence in X. bistipita and its pivotal evolutionary location provides insight into repeated evolution of bioluminescence across the tree of life. The rediscovery of the Californian millipede Xystocheir bistipita surprisingly reveals that the species is bioluminescent. Using molecular phylogenetics, we show that X. bistipita is the evolutionary sister group of Motyxia, the only genus of New World bioluminescent millipedes. We demonstrate that bioluminescence originated in the group’s most recent common ancestor and evolved by gradual, directional change through diversification. Because bioluminescence in Motyxia has been experimentally demonstrated to be aposematic, forewarning of the animal’s cyanide-based toxins, these results are contrary to aposematic theory and empirical evidence that a warning pattern cannot evolve gradually in unpalatable prey. However, gradual evolution of a warning pattern is plausible if faint light emission served another function and was co-opted as an aposematic signal later in the diversification of the genus. Luminescence in Motyxia stem-group taxa may have initially evolved to cope with reactive oxygen stress triggered by a hot, dry environment and was repurposed for aposematism by high-elevation crown-group taxa colonizing new habitats with varying levels of predation. The discovery of bioluminescence in X. bistipita and its pivotal phylogenetic location provides insight into the independent and repeated evolution of bioluminescence across the tree of life.
Effect of oxygen fluctuations on recombinant Escherichia coli fermentation

Escherichia coli DH5α, carrying the pUC19 plasmid for the lacZ fragment of β‐galactosidase and ampicillin resistance, was grown in a batch fermentor under conditions of fluctuating oxygen supply. A Monte Carlo method was used to control the on/off supply of air to simulate circulation of cells in a large fermentor. Rapid changes in oxygen supply reduced the rates of oxygen uptake the carbon dioxide release and prolonged the active second growth phase in batch culture, compared to growth with continuous aeration. Amplification of the plasmid was observed during the stationary phase when air supplied continuously, but not during the Monte Carlo experiments. © 1993 John Wiley & Sons, Inc.
Loopback Design for High Speed uProcessor IO Test

This paper presents the next generation AC IO Loopback design for two Intel processor architectures. Both designs detect I/O defects with 20 ps resolution and 50 ps jitter for up to 800 MHz bus speed. Even though the implementations differ in some aspects to accommodate two different bus architectures, the same prudent considerations for high speed operation, minimum test inaccuracy, and low implementation costs apply to both.
A surrogate-assisted differential evolution algorithm with dynamic parameters selection for solving expensive optimization problems

In this paper, a surrogate-assisted differential evolution (DE) algorithm is proposed to solve the computationally expensive optimization problems. In it, the Kriging model is used to approximate the objective function, while DE employs a mechanism to dynamically select the best performing combinations of parameters (amplification factor, crossover rate and population size). The performance of the algorithm is tested on the WCCI2014 competition on expensive single objective optimization problems. The experimental results demonstrate that the proposed algorithm has the ability to obtain good solutions.
Regulation of Cytokine-inducible Nitric Oxide Synthase in Cardiac Myocytes and Microvascular Endothelial Cells

Adult rat ventricular myocytes and cardiac microvascular endothelial cells (CMEC) both express an inducible nitric oxide synthase (iNOS or NOS2) following exposure to soluble inflammatory mediators. However, NOS2 gene expression is regulated differently in response to specific cytokines in each cell type. Interleukin-1β (IL-1β) induces NOS2 in both, whereas interferon (IFN) induces NOS2 expression in myocytes but not in CMEC. Therefore, we examined the specific signal transduction pathways that could regulate NOS2 mRNA levels, including activation of 44- and 42-kDa mitogen-activated protein kinases (MAPKs; ERK1/ERK2) and STAT1α, a transcriptional regulatory protein linked to cell membrane receptors. Although IL-1β treatment increased ERK1/ERK2 activities in both cell types, IFN activated these MAPKs only in myocytes. STAT1α phosphorylation, consistent with IFN-induced signaling, was readily apparent in both cell types, and binding of activated STAT1α from cytoplasmic or nuclear fractions from IFN-treated adult myocytes to a sis-inducible element could be demonstrated by gel-shift assay. The farnesyl transferase inhibitor BZA-5B blocked activation of ERK1/ERK2 and induction of NOS2 by IFN and IL-1β in myocytes. IL-1β and IFN-induced NOS2 gene expression in myocytes was also down-regulated by both protein kinase C (PKC) desensitization and by the PKC inhibitor bisindolylmaleimide, implicating PKC-linked activation of Ras or Raf in the induction of NOS2 by IL-1β and IFN in cardiac muscle cells. In CMEC, the MAPK kinase inhibitor PD 98059 blocked activation of ERK1/ERK2 and down-regulated IL-1β-mediated NOS2 induction, whereas activation of ERK2 in the absence of cytokines by okadaic acid, an inhibitor of phosphoserine protein phosphatases, also induced NOS2 mRNA. These data demonstrate that ERK1/ERK2 activation appears to be necessary for the induction of NOS2 by IL-1β and IFN in cardiac myocytes and CMEC. In the absence of ERK1/ERK2 activation by IFN in CMEC, phosphorylation of STAT1α is not sufficient for NOS2 gene expression. These overlapping yet distinct cellular responses to specific cytokines may serve to target NOS2 gene expression to specific cells or regions within the heart and also provide for rapid escalation of NO production if required for host defense.
Measuring Topological Number of a Chern-Insulator from Quench Dynamics

In this letter we address the issue that whether the topological number of a static Hamiltonian can be measured from a dynamical quench process. We focus on a two-band Chern insulator in twodimension, for instance, the Haldane model, whose quantum state is a pseudo-spin on the Bloch sphere. The dynamical process is described by a mapping from the [kx, ky, t] space to the Bloch sphere, characterized by the Hopf invariant. We show that, taking any two constant vectors on the Bloch sphere, the linking number of their inverse images of this mapping (i.e. two trajectories in the [kx, ky, t] space) exactly equals to the Chern number of the static Hamiltonian. Applying this result to a recent experiment from Hamburg group, we show that it is not the appearance of the phase vortices, but the linking number of the trajectories of these phase vortices that determines the phase boundary of the static Hamiltonian.
Expression of caveolin‐3 immunoreactivities in the developing sciatic nerve of the rat

Caveolae are formed by the caveolin (CAV) family of proteins, CAV‐1, ‐2, and ‐3. CAV‐1 and ‐2 are co‐expressed in many cell types, whereas CAV‐3 is muscle‐specific and mutation of the CAV‐3 gene causes muscular dystrophy. CAV‐3 has also been detected in brain astroglial cells and in peripheral nerves along with CAV‐1. Therefore, we sought to determine whether CAV‐3 protein is expressed in developing peripheral nerves by using immunohistochemistry and reverse transcription–polymerase chain reaction (RT‐PCR). We found that CAV‐3 immunoreactivities (IRs) were localized in the myelin sheath during peripheral nerve development. CAV‐3 IRs were intense during the early postnatal stage, but decreased as the peripheral nerves matured at postnatal weeks 3–5. CAV‐3 mRNA expression was also markedly decreased during postnatal development. Because the expression pattern of CAV‐3 IRs was opposite that of CAV‐1 IRs, CAV‐1 and ‐3 might be involved in different phases of peripheral nerve myelination and play complementary roles in myelin maturation and peripheral nerve development. © 2008 Wiley Periodicals, Inc. Muscle Nerve 2008
The effects of plague on the distribution of property: Ivrea, Northern Italy 1630

The demographic effects of the epidemics of plague in Early Modern Europe and their economic consequences illuminate the evolution of property structures and of wealth distribution during and after a mortality crisis. An analysis of the high-quality data available for the Italian city of Ivrea at the time of the 1630 plague shows the exceptional resilience of property structures. Like the social structures of the period, property structures were able to recover quickly, informed as they were by the lessons learnt by trial and error by the patrician families of the late Middle Ages, whose patrimonies had been badly damaged by the Black Death. In a period of recurrent catastrophes that struck European populations during the Old Demographic Regime, apparently ‘inegalitarian’ institutions seem to have had long-term ‘egalitarian’ effects.
A New Facility for the Experimental Investigation on Nano Heat Transfer between Gas Molecules and Ceramic Surfaces

Since the last decade, the interest has risen in nanoscaled technological products, which have advantages through their size effect. The size effect also plays a significant role in the area of microand nanoscale heat transfers. Many applications were developed using this effect, such as nanostructured porous media, e.g. Aerogels or ceramics. This experimental work is focused on the determination of thermal accommodation coefficients (TAC) on ceramic surfaces considering several influencing factors. TAC is influenced by temperature, kind of gas, kind of wall material, roughness, and contamination with adsorbed gas layers. To determine TAC, a parallel plate apparatus is used, although most of the measurements in the past have been arranged with the hot wire method. Using the parallel plates apparatus is advantageous due to its simpler machining of specimens and to analyze the effect of roughness. The apparatus is build similar to the well-known guarded hot-plate method using an unidirectional heat flux through the gas layer due to a small temperature gradient, which is provided by two different heat foils. The measurements take place between 30 and 100°C, 10−4, and 1 mbar.
Online data reduction with a DSP-FPGA multiprocessor system

For the detection of cracks and corrosion in pipelines an ultrasonic measuring system (pig) was developed. During the pipeline inspection there is no communication to the outside world, the accumulated data have to be stored on a mass storage device. The amount of data for a 250 kilometre run is in the range of about 700 TBytes at a rate of 2.8 GByte/s. There exists no robust mass storage device fitting into the pipeline in order to cope with this amount of data. To overcome these difficulties a massive parallel multiprocessing system with ASIC and DSP was developed. Each of the system modules has a computing power of more then 1200 MOPS. By the aid of this system a data reduction and compression of more than a factor 7000 is achieved. The complete computing power is installed in a volume the size of a shoe box.
Utilization of arginine by Klebsiella aerogenes

Klebsiella aerogenes utilized arginine as the sole source of carbon or nitrogen for growth. Arginine was degraded to 2-ketoglutarate and not to succinate, since a citrate synthaseless mutant grows on arginine as the only nitrogen source. When glucose was the energy source, all four nitrogen atoms of arginine were utilized. Three of them apparently did not pass through ammonia but were transferred by transamination, since a mutant unable to produce glutamate by glutamate synthase or glutamate dehydrogenase utilized three of four nitrogen atoms of arginine. Urea was not involved as intermediate, since a unreaseless mutant did not accumulate urea and grew on arginine as efficiently as the wild-type strain. Ornithine appeared to be an intermediate, because cells grown either on glucose and arginine or arginine alone could convert arginine in the presence of hydroxylamine to ornithine. This indicates that an amidinotransferase is the initiating enzyme of arginine breakdown. In addition, the cells contained a transaminase specific for ornithine. In contrast to the hydroxylamine-dependent reaction, this activity could be demonstrated in extracts. The arginine-utilizing system (aut) is apparently controlled like the enzymes responsible for the degradation of histidine (hut) through induction, catabolite repression, and activation by glutamine synthetase.
Perceptual interference between regional accent and voice/speech disorders

We present a study where we examined the influence of a regional accent in the perception of voice and/or speech disorders. These aspects are most of the time overshadowed in clinical context. This protocol, involving multiple sources of speech variations, is also interesting in perception theories. For the experiment, speakers with or without a Southern French accent and with or without speech/voice disorders were recorded on reading a text. The samples were then randomly played back to two groups of listeners (familiar vs non familiar with the regional accent), specialists in speech therapy. The task was the perceptual evaluation of voice quality, articulation disorders and dysprosody. We focused in this paper on the voice dimension. The main results on this part concern the weak influence of regional accent on the perception of moderate or severe dysphonia, where the speech signal is strongly disturbed by the disorder. By contrast, the effect of regional accent is important on normal voices perception: listeners non familiar with the regional accent judge speakers with accent without voice disorder as slightly dysphonic. This last result can be interpreted as a form of perceptual interference between different dimensions of speech variations around a central position.
The Amino Terminus of the Human Multidrug Resistance Transporter ABCC1 Has a U-shaped Folding with a Gating Function*

Multidrug resistance is a serious problem in successful cancer chemotherapy. Studies using model cell lines have demonstrated that overexpression of some members of the ATP-binding cassette (ABC) transporter superfamily, such as ABCC1, causes enhanced efflux and, thus, decreased accumulation of multiple anticancer drugs, which leads to increased cell survival. Unlike most other ABC transporters, ABCC1 has an additional membrane-spanning domain (MSD0) with a putative extracellular amino terminus of 32 amino acids. However, the function of MSD0 and the role of the extracellular amino terminus are largely unknown. In this study, we examined the structural folding and the function of the amino terminus. We found that it has a U-shaped folding with the bottom of the U-structure facing cytoplasm and both ends in extracellular space. We also found that this U-shaped amino terminus probably functions as a gate to regulate the drug transport activity of human ABCC1.
Opinion Mining Method for Sentiment Analysis

We are living in a world full of data. Every passing second, large data is generated by Social Media, ECommerce, Stock Exchange and many other platforms. Now-a-days, microblogging sites are used for manypurposes, such as communication, trend detection in marketing and business products, sentiment analysis, election prediction, education and much more, which has changed the public perspective of personalization and socialization. Twitter, is one of the major sources of data which generates more than 500 million of tweets per day. Every user usually shows his feeling or emotion about the topics of his interest. The reason of information gathering is to find out what the people feel. The decurtate length and the highly colloquial nature of tweets render it very difficult to automatically detect the sentiment and thus the requirement of sentiment analysis. Sentiment Analysis and summarization has in recent years caught the attention of many researchers, as on line text analysis is highly beneficial and asked for in various applications. A typical application is product-based sentiment summarization. This multi-document summarizationinforms users about pros and cons of available products. Sentiment analysis allows box office, social media, business analytics, market and FOREX rate prediction, and is also used in recommender system. In the present era sentiment analysis is most interesting research topic in text mining in the field of NLP in which a valuable knowledge extraction from textual data posted on the social media is an onerous task. A new framework has been proposed in this paper to normalize the text and judge the polarity of textual data aspositive, negative or neutral using an ETL (Extract, Transform, and Load) big data tool called Talend. The algorithm developed focusses on parallelism for performance speed and contributes towards the end result by comparing the accuracy with standard data set .
Piezoelectric self-sensing actuator for vibration suppression based on time-sharing method

A new time-sharing self-sensing method using piezoelectric actuators for active vibration suppression is proposed and investigated. This self-sensing technique is based on the idea that one PZT can have two electrical properties, namely whether it acts as a sensor or as an actuator. The actuation characteristics of the time-sharing self-sensing piezoelectric actuators were discussed. The shift between a sensor channel and an actuation channel results in a chopped control force. By applying the method of independent modal space control, a new procedure for the control force optimization of this type actuator is introduced. A numerical vibration suppression simulation demonstrated that the time-sharing self-sensing method works well on a beam structure. An experiment was carried out to test the practicability and the results proved the validity.
Long‐term depression of inhibitory synaptic transmission induced by spike‐timing dependent plasticity requires coactivation of endocannabinoid and muscarinic receptors

The precise timing of pre‐postsynaptic activity is vital for the induction of long‐term potentiation (LTP) or depression (LTD) at many central synapses. We show in synapses of rat CA1 pyramidal neurons in vitro that spike timing dependent plasticity (STDP) protocols that induce LTP at glutamatergic synapses can evoke LTD of inhibitory postsynaptic currents or STDP‐iLTD. The STDP‐iLTD requires a postsynaptic Ca2+ increase, a release of endocannabinoids (eCBs), the activation of type‐1 endocananabinoid receptors and presynaptic muscarinic receptors that mediate a decreased probability of GABA release. In contrast, the STDP‐iLTD is independent of the activation of nicotinic receptors, GABABRs and G protein‐coupled postsynaptic receptors at pyramidal neurons. We determine that the downregulation of presynaptic Cyclic adenosine monophosphate/protein Kinase A pathways is essential for the induction of STDP‐iLTD. These results suggest a novel mechanism by which the activation of cholinergic neurons and retrograde signaling by eCBs can modulate the efficacy of GABAergic synaptic transmission in ways that may contribute to information processing and storage in the hippocampus. © 2013 Wiley Periodicals, Inc.