Miracle-dz/UniFAR-FTUs huggingface dataset:
Are Still Fiducial Markers Alone Appropriate in the Image Guided Era for Prostate Cancer Radiotherapy? A Single Institu

Purpose: The purpose of this work is to assess the consistency of Fiducial Markers (FM) based IGRT in clinical practice and the magnitude of daily prostate gland displacements in a subgroup of patients carefully trained to maintain a constant and reproducible organ filling. Methods: A physician trained each patient in this selected 55 patients group, assuring a highly reproducible and well-administered self-preparation. Three FMs were implanted using a transrectal ultrasound technique. IGRT was achieved by daily single exposure MV portal images and, every 6 treatment sessions, double exposure portal images were acquired in order to evaluate differences in displacements between fiducial markers and bony structures. Results: There were no grade 3-4 complications (e.g. infections, bleeding or abscess) or significant patient reported discomfort related to FM insertion. Differences in displacements between FM and bony landmark resulted to be statistically significant (p<0,05), relating to a good self preparation. Displacement recorded during first five treatment sessions are not predictive of movement directions during remaining fractions. Conclusions: FMs give the opportunity, even in centers not equipped with in-room volumetric imaging systems, to perform IGRT. FMs-IGRT in combination to high quality patient rectal and bladder preparation allows an improvement of dose delivery and local control while reducing radiotherapyrelated toxicity and overall treatment time. Images control has to be carried out every day in order to be clinically useful as displacements occur in random directions.
Fast Simulation of Hyperplane-Truncated Multivariate Normal Distributions

We introduce a fast and easy-to-implement simulation algorithm for a multivariate normal distribution truncated on the intersection of a set of hyperplanes, and further generalize it to efficiently simulate random variables from a multivariate normal distribution whose covariance (precision) matrix can be decomposed as a positive-definite matrix minus (plus) a low-rank symmetric matrix. Example results illustrate the correctness and efficiency of the proposed simulation algorithms.
Optimization coaching for fork/join applications on the Java virtual machine

Developing parallel applications that exploit the hardware resources remains challenging. We tackle this issue for fork/join applications running on a single Java Virtual Machine (JVM) in a shared-memory multicore. An optimal fork/join application should maximize parallelism while minimizing overheads, and maximize locality while minimizing contention. Unfortunately, achieving these goals is challenging due to the complexity of tuning fork/join applications. As a result, fork/join applications often suffer from several performance issues such as excessive object creation and reclaiming, suboptimal forking, load imbalance, and inappropriate synchronization. In contrast to the extensive manual experimentation commonly required to properly tune fork/join applications, we devise a coaching tool able to automatically point developers to specific parts of such applications where performance problems originate and suggest concrete code modifications to fix them. Given the increasing popularity of fork/join parallelism on the JVM, many applications can benefit from our approach, including applications using standard Java APIs such as Streams and CompletableFuture.
Generative Adversarial Learning Towards Fast Weakly Supervised Detection

Weakly supervised object detection has attracted extensive research efforts in recent years. Without the need of annotating bounding boxes, the existing methods usually follow a two/multi-stage pipeline with an online compulsive stage to extract object proposals, which is an order of magnitude slower than fast fully supervised object detectors such as SSD [31] and YOLO [34]. In this paper, we speedup online weakly supervised object detectors by orders of magnitude by proposing a novel generative adversarial learning paradigm. In the proposed paradigm, the generator is a one-stage object detector to generate bounding boxes from images. To guide the learning of object-level generator, a surrogator is introduced to mine high-quality bounding boxes for training. We further adapt a structural similarity loss in combination with an adversarial loss into the training objective, which solves the challenge that the bounding boxes produced by the surrogator may not well capture their ground truth. Our one-stage detector outperforms all existing schemes in terms of detection accuracy, running at 118 frames per second, which is up to 438Ã— faster than the state-of-the-art weakly supervised detectors [8, 30, 15, 27, 45]. The code will be available publicly soon.
Convergence analysis of time-discretisation schemes for rate-independent systems

It is well known that rate-independent systems involving nonconvex energy functionals in general do not allow for time-continuous solutions even if the given data are smooth. In the last years, several solution concepts were proposed that include discontinuities in the notion of solution, among them the class of global energetic solutions and the class of BV-solutions. In general, these solution concepts are not equivalent and numerical schemes are needed that reliably approximate that type of solutions one is interested in. In this paper, we analyse the convergence of solutions of three time-discretisation schemes, namely an approach based on local minimisation, a relaxed version of it and an alternate minimisation scheme. For all three cases, we show that under suitable conditions on the discretisation parameters discrete solutions converge to limit functions that belong to the class of BV-solutions. The proofs rely on a reparametrisation argument. We illustrate the different schemes with a toy example.
The aim of this study is to compare an intravenous ( IV ) catheter system which uses a retractable guidewire ( RG-IV ) designed to facilitate IV placement with a conventional IV ( CIV ) catheter control ”

MATERIALS AND METHODS: A prospective, randomized design was used. Patients referred to interventional radiology for outpatient procedures were offered participation. Enrollment occurred between August and November 2013. Patients were assigned to receive the RG-IV or C-IV in a 1:1 randomization scheme. After assignment, up to three attempts by a registered nurse occurred with the assigned device; if all three attempts failed, crossover to the other device occurred. The primary outcome variable was first-attempt success at IV placement. Secondary outcome variables included patient and clinician satisfaction, number of attempts, and time to successful placement. Two hundred twenty patients were enrolled (139 men, 81 women) in the study.
A Study on Role of Personality Traits and Stress Coping Styles in Mental Wellbeing of Students

This research evaluates role of personality traits and stress coping styles in mental wellbeing of the considered students. 200 students were selected by adopting clustered multistage sampling. Then, they were asked to complete three inventories: Short Personality 5-Factor Inventory, Inventory of Stress Coping Styles (Calcic et al., 2008), and Ryff's Psychological Well-being Scale. After collecting completed questionnaires and recording them, the researchers performed Pearson's correlation analysis and multivariate regression analysis for examining the hypotheses. As the findings demonstrate, agreeableness, flexibility, extroversion, and neuroticism are significantly correlated with mental wellbeing. Additionally, stress coping styles are positively interrelated with mental wellbeing. Also, correlation coefficients are increased by 0.62 by adding agreeableness, neuroticism, extroversion, emotion orientation, and flexibility.
A Non-Linear Feedback Current Driver With Automatic Phase Compensation for Bioimpedance Applications

In a conventional sinewave current driver for electrical impedance spectroscopy, as the frequency is increased the input/output phase delay of the current driver increases due to limited bandwidth. The required maximum phase delays of < 4° mean that operation is limited to about 1/12 of the driver bandwidth. A new phase compensation scheme is presented to reduce the phase delay at higher frequencies and can extend the useful operating frequency range of a current driver. The system is capable of reducing the phase error due to the current driver by an appreciable level so that it can operate much nearer the pole frequency of the driver. An integrated circuit was fabricated in a 0.35-<inline-formula> <tex-math notation="LaTeX">${\mu }\text{m}$ </tex-math></inline-formula> CMOS process technology, which provides a phase error reduction from 22° to 3° at 3 MHz. Its core occupies a silicon area of 1.2 mm<sup>2</sup>. It operates from a ±2.5 V power supply and can deliver output currents up to 1.8 mA<sub>p-p</sub> at 3 MHz.
On the possible values of the orbit distance between a near-Earth asteroid and the Earth

We consider all the possible trajectories of a near-Earth asteroid (NEA), corresponding to the whole set of heliocentric orbital elements with perihelion distance q ≤ 1.3 au and eccentricity e ≤ 1 (NEA class). For these hypothetical trajectories, we study the range of the values of the distance from the trajectory of the Earth (assumed on a circular orbit) as a function of selected orbital elements of the asteroid. The results of this geometric approach are useful to explain some aspects of the orbital distribution of the known NEAs. We also show that the maximal orbit distance between an object in the NEA class and the Earth is attained by a parabolic orbit, with apsidal line orthogonal to the ecliptic plane. It turns out that the threshold value of q for the NEA class (qmax = 1.3 au) is very close to a critical value, below which the above result is not valid. ‘Nothing was visible, nor could be visible, to us, except Straight Lines’, E. A. Abbott, Flatland.
Intraabdominal Hemorrage Due to Hepatic Cyst Rupture During CPR: Case Report Kardiyopulmoner Canlandirma Sirasinda Hepatik Kist Rüptürüne Bağli İntraabdominal Hemoraji: Olgu Sunumu

Cardiopulmonary Resuscitation (CPR) improves survival in selected patient populations. However, in the surviving group, postresuscitative unexpected complications can occur due to external chest compression. Visceral organ injuries are a part of their. Liver cysts are usually accompanied by an autosomal dominant polycystic kidney disease. In patients with chronic renal failure, bleeding tendency in uremia is due. As the effect of anticoogulant drugs used during dialysis Also, visceral organ bleeding due to injury may be easier. In such patients, ongoing hemodynamic instabillite after CPR, should be regarded as multidisciplinary. In this article, massive intra-abdominal hemorrhage due to rupture of hepatic cyst after CPR, patient with peritoneal dialysis treatment is presented.
Trajectory Design and Feedforward Control for Car Parking

In this paper a general two-step trajectory planning algorithm from robotics literature is applied to generate suitable trajectories for an autonomous parking maneuver of a car. First, a collision-free curve between a given start and a desired goal configuration within the parking space is planned ignoring the kinematic restrictions on the movement of the car. Second, the collision-free curve is converted into a feasible collision-free trajectory, which can be exactly followed by the car. It is shown how this general planning scheme must be adapted to meet the requirements of the automotive industry without losing important properties like the completeness of the algorithm.
In silico analysis of Treponema and Brachyspira genomes

Spirochaetal bacteria are highly diverse in terms of life style, growth requirements and virulence, but they all belong to a monophyletic ancient lineage. Many spirochaetes are difficult to culture or have fastidious growth requirements. Genus Brachyspira and genus Treponema, are two important members of phylum spirochetes that include well known pathogens, such as T.pallidum subsp. pallidum and B. hyodysenteriae. Other members of the phylum include T.pedis, associated with both bovine digital dermatitis (BDD) in cattle and necrotic skin lesions in pigs, T.phagedenis associated with BDD, and "B.suanatina", which has been reported in connection with swine dysentery-like enteric disease in pigs. All these bacteria are thus associated with significant health problems in farm animals leading to economic losses. The aims of this thesis were to identify and characterize potential pathogenic factors in T.pedis and T. phagedenis and to study the genomic characteristics of B. suanatina for a complete species validation and description. Assembly, annotation and bioinformatics analysis of the genome sequence of T. phagedenis strain V1 and T. pedis strain TA4 were performed. The complete genome of T. pedis strain TA4 was compared to that of T. denticola, a species associated with human periodontal disease. Results of the analysis showed close relatedness between these two bacterial species. Some of the pathogenicity related genes that are already known in T. denticola were also found in T. pedis strain TA4. In the genome of T. phagedenis strain V1, homologous proteins to known pathogenicity factors in T. denticola and T. pallidum were found and a locus encoding antigenic lipoproteins with potential for antigenic variation was characterized To identify the taxonomical position of B. suanatina, we performed assembly, annotation and phylogenetic analysis of the B. suanatina strain AN4859/03 genome along with its comparison with B. hyodysenteriae and other Brachyspira species. Comparative analysis suggested that B. suanatina is a novel species, though phenotypically it showed no difference from B. hyodysenteriae.
EFFECTS OF ECOLOGICAL AND TOPOGRAPHIC CONDITIONS ON OIL CONTENT AND FATTY ACID COMPOSITION IN SUNFLOWER

TURHAN, H. , N. CITAK, H. PEHLIVANOGLU and Z. MENGUL, 2010. Effects of ecological and topographic conditions on oil content and fatty acid composition in sunflower. Bulg. J. Agric. Sci., 16: 553-558 Oil concentration and quality in sunflower (Helianthus annuus L.) are very much affected by environmental conditions such as temperature, precipitation, relative humidity, cloudiness and so on. Sunflower oil quality is determined by its fatty acid composition. Therefore, the objective of this study was to investigate the effect of ecological and topographic conditions on oil content and fatty acid composition in a standard sunflower hybrid. The samples were taken from six zones determined according to their ecological and topographical features. The results showed that oil content and fatty acid composition significantly changed by ecological and topographic conditions. Oil content in seeds varied 39.82-44.30% depending on location. Percentages of major fatty acids such as linoleic, oleic, palmitic and stearic acid were also significantly affected by growth location. As a result, environment or growth condition had a significant effect on sunflower oil content and fatty acid composition. Therefore, growth location is an important factor for meeting market requirements of sunflower oil in terms of quality.
Faster development does not lead to correlated evolution of greater pre-adult competitive ability in Drosophila melanogaster

In comparisons across Drosophila species, faster pre-adult development is phenotypically correlated with increased pre-adult competitive ability, suggesting that these two traits may also be evolutionary correlates of one another. However, correlations between traits within- and among- species can differ, and in most cases it is the within-species genetic correlations that are likely to act as constraints on adaptive evolution. Moreover, laboratory studies on Drosophila melanogaster have shown that the suite of traits that evolves in populations subjected to selection for faster development is the opposite of the traits that evolve in populations selected for increased pre-adult competitive ability. This observation led us to propose that, despite having a higher carrying capacity and a reduced minimum food requirement for completing development than controls, D. melanogaster populations subjected to selection for faster development should have lower competitive ability than controls owing to their reduced larval feeding rates and urea tolerance. Here, we describe results from pre-adult competition experiments that clearly show that the faster developing populations are substantially poorer competitors than controls when reared at high density in competition with a marked mutant strain. We briefly discuss these results in the context of different formulations of density-dependent selection theory.
COMPACT SERRATED NOTCH BAND MIMO ANTENNA FOR UWB APPLICATIONS

A compact UWB antenna is been designed to notch Wi-Max (3.3GHz-3.7GHz) and W-LAN (5.15GHz-5.85GHZ) operating bands. The antenna comprises of two square slottedmonopoles with serrated edges on the patch surface and Tshaped stub as defected ground structure. Coplanar waveguide feeding is used in the antenna structure at two ports with the impedance of 50 ohms. Both simulation and measurement aredone to study the antenna parameters like return loss, radiation-characteristics, impedance matching and isolation between the two ports. To enhance isolation a slot is cut on the T-shaped ground surface. Two inverted L strips are added on either sides of the groundplane and a slot cut on the ground plane finally form T-shape defected ground structure. The proposed antenna notches two application bands in the UWB range with low mutual coupling which makes the antenna a suitable model for desired applications.
ConnectionLens: Finding Connections Across Heterogeneous Data Sources

Nowadays, journalism is facilitated by the existence of large amounts of publicly available digital data sources. In particular, journalists can do investigative work, which typically consists on keyword-based searches over many heterogeneous, independently produced and dynamic data sources, to obtain useful, interconnecting and traceable information. We propose to demonstrate C onnection L ens , a system based on a novel algorithm for keyword search across heterogeneous data sources. Our demonstration scenarios are based on use cases suggested by journalists from the french journal Le Monde, with whom we collaborate.
Gluttony and Sloth? Calories, Labour Market Activity and the Rise of Obesity

The rise in obesity has largely been attributed to an increase in calorie consumption. We show that official government household survey data suggest that calories have declined in England from 1980 to 2013; while there has been an increase in calories from food out at restaurants, fast food, soft drinks and confectionery, overall there has been a decrease in total calories purchased. Households have shifted towards more expensive calories, both by substituting away from home production towards market production, and substituting towards higher quality foods. We show that this decline in calories can be rationalised with weight gain by the decline in the strenuousness of work and daily life.
Taxonomic revision of the genus Chorda (Chordaceae, Laminariales) on the basis of sporophyte anatomy and molecular phylogeny

H. Sasaki and H. Kawai. 2007. Taxonomic revision of the genus Chorda (Chordaceae, Laminariales) on the basis of sporophyte anatomy and molecular phylogeny. Phycologia 46: 10–21 DOI: 10.2216/06-06.1 Chorda kikonaiensis Sasaki & Kawai sp. nov. is newly described from Hokkaido, Japan, on the basis of morphological and molecular data. Furthermore, based on the latter, the common Chorda species that has been identified as Chorda filum in Japan is shown to be independent from the European (true) Chorda filum at the species level. Therefore, Chorda asiatica Sasaki & Kawai sp. nov. is described for the cryptic Japanese taxon. Chorda kikonaiensis resembles C. filum and C. asiatica, but is distinguished by the shorter (0.4–1.3 m) and softer sporophyte, and the thinner cortex composed of fewer (2–4) cells. The independence of this species is further supported by molecular phylogenetic analyses using rbcL gene and internal transcribed spacer (ITS) rDNA sequences. Chorda asiatica is more variable in morphology (length of erect thallus and number of cell layers composing the cortex) than C. kikoniensis and C. rigida, and is difficult to distinguish from C. filum on the basis of morphology, but is clearly separated from the other species (C. filum, C. kikoniensis and C. rigida) on the basis of ITS rDNA data. Chorda filum is distributed in the Atlantic, whereas C. asiatica, C. kikonaiensis and C. rigida are distributed in the Pacific Ocean. Furthermore, the presence of one or two additional cryptic species is suggested in the northern Pacific using molecular data. Therefore, it is shown that the genus Chorda has considerably higher taxonomic and genetic diversity in the Pacific than in the Atlantic. Although no molecular data are available for other eastern Asian (southeastern Russian coast, Korea and China) Chorda species, on the basis of morphology and geographical distributions, they are likely referable to C. asiatica.
Automated DTI analysis of MS lesions and their contralateral regions of interest using the mid-sagittal plane as a reference

Diffusion tensor MRI (DT-MRI) allows the in vivo assessment of the abnormalities of white matter in multiple sclerosis (MS). DT-MRI is complementary to conventional MRI sequences where such abnormalities are often not visible. Most studies have shown differences of mean diffusivity (MD) and fractional anisotropy (FA) between patients and controls in MS lesions (MSL) and normal appearing white matter (NAWM) based on histogram analyses. However, the majority of these studies are based on histogram analysis, i.e. local information of DT-MRI is lost, and moreover a number of those studies were not conclusive, partly explained by methodological issues, because these tensor indices vary within the brain, which is likely to make such global, histogram-based analyses, fail. Here we propose a new framework to compare these indices between MSL and NAWM and between two populations (patients and controls). First, MSL are manually delineated in MS patients. The mid-sagittal plane is then automatically computed, allowing to deﬁne a contralateral region of interest (ROI) in NAWM for each MSL. This allows the local comparison of DTI indices in anatomically similar regions in each MS patient. Second, each MS patient is linearly registered to each control subject, and the same left-right comparison between MSL and contralateral NAWM is then performed in controls. The results (ANOVA with multiple comparisons procedure) show that 1) FA values are lower in MSL than in contralateral NAWM in MS patients (p < 0.05) but not in controls, 2) FA values are lower in MS patients (MSL and contralateral NAWM) compared to controls (p < 0.05), 3) MD values are not different between MSL/contralateral NAWM in MS patients and controls. We also show that combining diﬀerent preprocessing methods (3 estimation methods and 3 distortion correction methods) has little impact on such results. Nevertheless, our fully automated approach is superior to manual or semi-automated DT-MRI analyses regarding the robustness of the results (reproducibility and accuracy).