Miracle-dz/UniFAR-FTUs huggingface dataset:
Assessment of the mandibular symphysis of Caucasian Brazilian adults with well-balanced faces and normal occlusion: the influence of gender and facial type

OBJECTIVE: This study aimed to establish cephalometric reference values for mandibular symphysis in adults. Dentoalveolar, skeletal and soft tissue variables were measured considering the influence of gender and facial type. METHODS: The sample consisted of sixty cephalometric radiographs of white Brazilian adult patients, with a mean age of 27 years and 6 months, who had not undergone orthodontic treatment and who presented well-balanced faces and normal occlusion. The sample was standardized according to gender (30 males and 30 females) and facial type (20 were dolichofacial, 20 mesofacial and 20 brachyfacial). RESULTS: The results showed that male and female symphyses are similar, except for symphyseal height, which was greater in males. In terms of facial type, the dolichofacial group presented narrower symphysis in dentoalveolar and basal areas, with a more accentuated lingual dentoalveolar inclination. CONCLUSION: The brachyfacial group showed broader symphysis in the dentoalveolar and basal areas and a greater buccal dentoalveolar inclination. The projection of the chin was 6.67 mm below the subnasal vertical line and there was no significant difference between the genders or facial types.
Serological Cross-Reactivity of Alphaviruses To Chikungunya Specific Antibodies And Its Relationship To Their Structural proteins

Alphaviruses are small, enveloped viruses containing a single-stranded, positive-sense RNA genome and belongs to the family Togaviridae. Most of these viruses are transmitted by mosquitoes and infect a variety of mammals and birds. The purpose of this study was to assess the reactivity of selected alphaviruses, namely O`nyong`nyong virus (ONNV), Ndumu virus (NDUV), Semliki forest virus (SFV) and Sindbis virus (SINV) to an in-house antigen detection Enzyme-Linked Immunosorbent Assay (ELISA) developed from Chikungunya virus (CHIKV) specific antibodies. Secondly, the cross-reactivity of these alphaviruses and their genetic characteristics when compared to CHIKV was also to be analyzed.This was done by testing each of the viruses infected culture fluid with the antigen detection ELISA, determining percentage identity and performing a phylogenetic analysis. O`nyong`nyong showed reactivity with CHIKV specific assay, while all the other alphaviruses were negative. Further analysis of these alphaviruses showed percentage identity of 14.1% for ONNV, 35.8% for SFV, 43.8% for NDUV and 54.7% for SINV. Phylogenetic analysis of the structural proteins of CHIKV and the other alphaviruses sequences sourced from the GenBank, showed CHIKV and ONNV clustering closely together in a sub-clade as expected due to high sequence similarity between the two viruses. Sindbis, NDUV and SFV were a little distant in the phylogeny, clustering in different clades, showing a distant geographical and evolutionary relationship. In conclusion, the reactivity of these viruses with CHIKV specific assay was correlated to the similarity of amino acids as shown by ONNV. The viruses that showed no reactivity with the assay showed minimal similarity of amino acids in the structural proteins when compared to CHIKV. This information would be useful during the development of differential diagnostics, so that accurate disease diagnosis is done and thereafter appropriate outbreak responses like symptoms management, quarantine and vector control is put in place.
Corticosteroid-induced central serous chorioretinopathy in patients with ocular inflammatory disorders.

BACKGROUND Development of central serous chorioretinopathy (CSC) following the administration of corticosteroids by diverse routes is a well-known fact. We report acute visual loss after the use of systemic corticosteroids in three patients with long-standing ocular inflammatory disorders in whom CSC could initially be misinterpreted as a worsening of the primary inflammatory condition. METHODS We analyzed the clinical findings and the fluorescein and indocyanine green (ICG) angiographic signs in those three patients. RESULTS The first patient had birdshot chorioretinopathy with minimal functional impairment for several years without treatment. When visual acuity and fields deteriorated, systemic corticosteroids were administered resulting in improved inflammatory and functional parameters during the first 2 months. Subsequently, the visual acuity of his left eye decreased due to CSC. The second patient had Vogt-Koyanagi-Harada disease with five episodes of acute inflammation. She was treated each time with systemic corticosteroids, but thrice her visual acuity deteriorated, caused by CSC. The third patient presented with scleritis of his right eye related to relapsing polychondritis. Massive oral corticosteroids were given, soon followed by the development of CSC in the right eye. Fluorescein and ICG angiographic signs were typical for CSC in all three patients. Cyclosporine was introduced in the two first patients and cyclophosphamide in the third patient, in parallel with tapering of oral corticosteroids. Progressive regression of CSC occurred in all three patients. CONCLUSION The potentially deleterious effects of corticosteroids, favoring CSC, are well-known. They should be borne in mind when an unexpected clinical and angiographic evolution compatible with CSC develops in an uveitis patient treated with corticosteroids.
Mean Field Games with Density Constraints

The present thesis focuses on a recent theory called “Mean Field Games”, introduced in 2006 by J.-M. Lasry and P.-L. Lions (see [18], [19], [20], [22]). Its goal is to study some first order Mean Field Games systems with density constraints. The density constraints are natural to assume, in the sense that agents usually do not want to go through places, where already there are many other agents. The model which is presented and studied is due to F. Santambrogio (see [30]) and it uses some ideas from recent works about crowd motion theory (see [23], [24], [25], [29]). In the Introduction we briefly present the theory of Mean Field Games, using the original works by Lasry and Lions and the lecture notes of P. Cardaliaguet ([8]). Here is also presented a second order and first order system, the latter represents the main subject of study of the thesis. In Chapter 1 we give some well-known definitions and results from the theory of optimal transportation. This theory seems to be very useful also in the study of MFG. The basic references of this topic are the two monographs by C. Villani (see [33] and [34]) and in this chapter we also use lecture notes of F. Santambrogio ([31]). In Chapter 2 our aim is to present some well-known facts about optimal control theory and semi-concavity. Here the reference is mainly the book of P. Cannarsa and C. Sinestrari ([7]) which is a very important tool in our situation. In Chapter 3 following the lecture notes by P. Cardaliaguet ([8]), which contain the lectures given by P.-L. Lions in Collège de France (years 2007 and 2008), we present a fixed point technique to obtain existence for a standard MFG system (without density constraints). We also present the assumptions (and the proof of the theorem) which are used to obtain uniqueness in this case. More or less we want to follow a similar way, using a fixed point scheme to study the case with density constraints. In Chapter 4 we finally arrive to the model given by F. Santambrogio and try to construct a fixed point scheme to show the existence of a solution of our MFG system with density constraints. On this way of studying this system we realize that it is not so obvious to adapt the techniques from the usual case, hence we have to modify from time to time the ideas and at the end the problem is reduced to finding a fixed point of a multivalued operator. Later in this chapter we give some possible further study possibilities in this topic and end the thesis with final conclusions. Basically this is the chapter which contains some original works and adaptations of other results (form the theory of crowd motion and from the theory of usual MFG theory) to our case.
Prevention of Anemia in Patients with Solid Tumors Receiving Platinum-Based Chemotherapy by Recombinant Human Erythropoietin (rHuEpo): A Prospective, Open Label, Randomized Trial by the Hellenic Cooperative Oncology Group

Objectives: Platinum compounds are commonly associated with significant anemia. Erythropoietin administration has been found effective in correcting anemia in patients with solid tumors receiving chemotherapy. We conducted a randomized, open label study to assess the efficacy of erythropoietin in preventing transfusions and significant anemia (hemoglobin <10 g/dl) in patients with solid tumors receiving platinum-based chemotherapy. Methods: One hundred forty-four patients with hemoglobin <13 g/dl were included in this study (72 in each arm). Patients in the treatment arm received 10,000 U of recombinant human erythropoietin (rHuEPO) thrice weekly s.c. during platinum-based chemotherapy, while patients in the control arm received no treatment. Results: All patients were evaluable for efficacy. Transfusions were reduced by the administration of rHuEPO (15.3 vs. 33.3%, p = 0.019), and fewer patients developed significant anemia (16.6 vs. 45.8%, p < 0.0001). Subgroup analysis showed that patients with observed to predicted (O/P) serum erythropoietin levels ≤0.9 and responders to chemotherapy benefited from erythropoietin administration in contrast to patients with O/P >0.9 or non-responders. Conclusions: rHuEPO at a dose of 10,000 U thrice weekly prevents transfusions and development of significant anemia in patients with solid tumors receiving platinum-based chemotherapy.
Unstructured text comprehension and question answering

This thesis deals with comprehension of unstructured text and question answering. Specifically we focus the benefits of transfer learning. We show several experiments where we employ transfer learning to adjust model created on general large QA dataset (SQuAD) with data from smaller topic specific datasets. We explore influence of transfer learning on datasets focusing on specific topic not included in the main domain.
An Improved Design of Equal-Split Filtering Divider with Integrated Coupled-Line Band-Pass Filter

─ A novel methodology is proposed for achieving good output port isolation and return loss in a micro-strip filtering divider design with integrated coupled-line (CPL) band-pass filter (BPF). The designed filtering divider shows improved performance parameters as compared to previously reported work. It is proposed that by incorporating an extended transmission line (TL) and a conventional resistor as isolation elements, in addition to good even mode response (i.e., insertion loss IL, and input port return loss RL), the odd mode response (i.e., output port RL and isolation) can simultaneously be improved. In addition, two transmission zeros are realized in the vicinity of the pass band providing a reasonable skirt. Firstly, the coupled-line filter (CPLF) is matched to 70. 7Ω and subsequently integrated in place of conventional quarter wavelength transformers in a Wilkinson Power Divider (WPD) for equal division. Under these matched conditions, it is shown that a TL section and isolation resistor sufficed to achieve a reasonable output port return loss (RL) and isolation in the resulting filtering divider. Experimental validation of the proposed methodology comes from the measurements results of the fabricated CPL filtering divider designed at 3 GHz conforming reasonably to the simulated ones. For instance, 1 dB fractional bandwidth of 15.3%, port isolation of better than 31 dB and good out-of-band performance up to 2.67f0 were experimentally achieved. Index Terms ─ Band-pass filter, coupled line filter, equal split, filtering divider.
BIOMIMETIC ENAMEL REMINERALIZATION USING CHITOSAN HYDROGEL (AN IN VITRO STUDY)

INTRODUCTION: Biomimetic enamel reconstruction is a significant topic in material science and dentistry as a novel approach for the treatment of dental caries or erosion. Compared to other conventional treatments, biocompatible and biodegradable chitosan hydrogel, with its antimicrobial properties shows promise as a biomaterial for the prevention, restoration, and treatment of defective enamel. OBJECTIVES: The present study was designed to investigate the effect of chitosan on the remineralization of enamel. MATERIALS AND METHODS Sound human premolars extracted for orthodontic reasons and were sectioned into 1mm thick slices.30 slices were selected and randomly divided into 3 equal groups (10 slices per group) as follows: GroupI: Control group, the slices were etched with 37% phosphoric acid for 30 seconds. Group II: The slices were etched with 37% phosphoric acid for 30 seconds, coated with bonding agent and chitosan hydrogel. Then slices were incubated at 37oC in artificial saliva solution for 5 days. Group III: The slices were etched with 37% phosphoric acid for 30 seconds, coated with bonding agent and chitosan hydrogel. Then slices were incubated at 37oC in artificial saliva solution for 10 days. After remineralization, the enamel surfaces were ultrasonically cleaned for 2 minutes and analyzed with scanning electron microscope (SEM) in order to observe induced structural changes on the enamel surface then elemental analysis and Ca/P ratios were carried out using Energy Dispersive Analysis X-Ray (EDAX) spectrometer. The obtained data were statistically analyzed. RESULTS: Morphological changes on the enamel surface after application of chitosan observed by SEM revealed the regeneration of an enamel-like layer in both treated samples. There was a statistically significant difference between the Ca/P ratios of the treatment groups compared to that of the control group. CONCLUSIONS: The ultrastructural and elemental alterations noticed in this study substantiate the use of chitosan in cases of dental erosions
On the Role of Retaliation in Trade Agreements

This paper analyzes the role of retaliation in trade agreements. It shows that, in the presence of private information, retaliation can always be used to increase the welfare derived from such agreements by the participating governments. In particular, it is shown that retaliation is a necessary feature of any efficient equilibrium. We argue that retaliation would not be necessary if governments could resort to international transfers or export subsidies to compensate for terms-of-trade externalities. Within the current world trading system, though, in which transfers are seldom observed whereas export subsidies are prohibited, the use of the remaining trade instruments in a retaliatory fashion might be optimal. The model is used to interpret the retaliatoy use of antidumping observed in the last decades, and the proliferation of these measures relative to other trade remedies.
Advanced Interaction Techniques for Handheld Mobile Augmented Reality

Research in the field of handheld augmented reality has so far often focused on technical tracking and visualization challenges, while the investigation of interaction possibilities beyond the classical ‘magic lens’ paradigm has been neglected. We argue for a closer investigation of advanced interaction techniques that could be used in combination with handheld augmented reality visualizations. We introduce several such promising ‘interactive magic lens’ techniques enabled on handhelds and finally briefly describe our current efforts towards the recognition and usage of finger gestures within interactive magic lenses.
A Study on the Characteristics Due to Pole-Arc to Pole-Pitch Ratio and Saliency to Improve Torque Performance of IPMSM

In this paper, the design methodology of a rotor for the interior permanent magnet motor (IPMSM) considering pole-arc to pole-pitch ratio and saliency parameter owing to PM and duct structure is proposed in order to improve the characteristics such as average torque, torque ripple, cogging torque and back EMF waveform. Especially, demagnetization effect due to duct design is analyzed by using the finite element method (FEM)
Biotrans: Description of a Data Transfer Program for the Biostator

Glucose clamp experiments are often performed by means of a Biostator. Due to the fact that this device does not provide data storage, data analysis has to be done manually or data must be fed into the computer. In order to enhance the efficacy of data analysis and to avoid time consuming work, a data acquisition program (Biotrans) has been developed which allows data transfer from the Biostator into an IBM compatible computer. After a complex analysis of incoming data, Biotrans provides on-line data storage and display features (blood glucose concentrations and glucose infusion rate). Off-line analysis of the stored data is accomplished by conventional spread sheet programs, thus permitting complex data calculations and graphic presentation. In more than 300 glucose clamp experiments performed within the last three years Biotrans was an important tool providing data storage capabilities, better control of ongoing events during an experiment and rapid and reliable data analysis immediately after completion of individual experiments.
The peroxin Pex17p of the yeast Yarrowia lipolytica is associated peripherally with the peroxisomal membrane and is required for the import of a subset of matrix proteins

PEX genes encode peroxins, which are required for the biogenesis of peroxisomes. The Yarrowia lipolytica PEX17 gene encodes the peroxin Pex17p, which is 671 amino acids in length and has a predicted molecular mass of 75,588 Da. Pex17p is peripherally associated with the peroxisomal membrane. The carboxyl-terminal tripeptide, Gly-Thr-Leu, of Pex17p is not necessary for its targeting to peroxisomes. Synthesis of Pex17p is low in cells grown in glucose-containing medium and increases after the cells are shifted to oleic acid-containing medium. Cells of the pex17-1 mutant, the original mutant strain, and the pex17-KA mutant, a strain in which most of the PEX17 gene is deleted, fail to form normal peroxisomes but instead contain numerous large, multimembraned structures. The import of peroxisomal matrix proteins in these mutants is selectively impaired. This selective import is not a function of the nature of the peroxisomal targeting signal. We suggest a regulatory role for Pex17p in the import of a subset of matrix proteins into peroxisomes.
A Study on Effective R & D Analysis Using Fuzzy Engineering & Cognitive inference systems

It is important to examine the feasibility of the project to evaluate the national R & D project. Therefore, in order to conduct a feasibility study, it is necessary to base the data on the determinants of the evaluation factor, but there may be a possibility of overlap between the evaluation factors. There is also a difficulty in deducing the future situation through past data. The inference system proposed in this study is based on the fuzzy system, which has a function to clarify the relationship between some redundant and ambiguous data, and the reliability of R & D validity can be increased. It is a system that combines Bayesian networks that can infer future situations. With this system, it is possible to make more clear decision making support and it can help the future direction of R & D investment.
Low Dark Current and Low Noise 0 . 9 m Pixel in a 45 nm Stacked CMOS Image Sensor Process Technology

A 0.9 m pixel with well-balanced light and dark performance by making full use of a highly manufacturable 45 nm advanced technology incorporated with stacked CMOS image sensor (CIS) is presented. The 45 nm advanced technology is desirable for submicron pixel generation because of tighter design rule and higher controllability for process variation. In addition, the flexibility of stacked CIS process improves pixel performance. In this work, we demonstrated low dark current of 3.2 e/s at 60 °C, ultra-low read noise of 0.90 e rms, a high full well capacity (FWC) of 4,100 e, and blooming free in a 0.9 m pixel with pixel supply voltage of 2.8 V.
Aspects of Strongly Correlated Many-Body Fermi Systems

William J. Porter III: ASPECTS OF STRONGLY CORRELATED MANY-BODY FERMI SYSTEMS (Under the direction of Joaqúın E. Drut) A, by now, well-known signal-to-noise problem plagues Monte Carlo calculations of quantum-informationtheoretic observables in systems of interacting fermions, particularly the Rényi entanglement entropies Sn, even in many cases where the infamous sign problem does not appear. Several methods have been put forward to circumvent this affliction including ensemble-switching techniques using auxiliary partition-function ratios. This dissertation presents an algorithm that modifies the recently proposed free-fermion decomposition in an essential way: we incorporate the entanglement-sensitive correlations directly into the probability measure in a natural way. Implementing this algorithm, we demonstrate that it is compatible with the hybrid Monte Carlo algorithm, the workhorse of the lattice quantum chromodynamics community and an essential tool for studying gauge theories that contain dynamical fermions. By studying a simple one-dimensional Hubbard model, we demonstrate that our method does not exhibit the same debilitating numerical difficulties that näıve attempts to study entanglement often encounter. Following that, we illustrate some key probabilistic insights, using intuition derived from the previous method and its successes to construct a simpler, better behaved, and more elegant algorithm. Using this method, in combination with new identities which allow us to avoid seemingly necessary numerical difficulties, the inversion of the restricted one-body density matrices, we compute high order Rényi entropies and perform a thorough comparison to this new algorithm’s predecessor using the Hubbard model mentioned before. Finally, we characterize non-perturbatively the Rényi entropies of degree n = 2, 3, 4, and 5 of three-dimensional, strongly coupled many-fermion systems in the scale-invariant regime of short interaction range and large scattering length, i.e. in the unitary limit using the algorithms detailed herein. We also detail an exact, few-body projective method which we use to characterize the entanglement properties of the two-body sector across a broad range of attractive couplings. In the many-body case, we determine universal scaling properties of this system, and for the two-body case, we compute the entanglement spectrum exactly, successfully characterizing a vast range of entanglement behavior across the BCS-BEC crossover.
Study and Analysis of Prediction Model for Heart Disease : An Optimization Approach using Genetic Algorithm

In the medical field, the diagnosis of heart disease is the most difficult task. The diagnosis of heart disease is difficult as a decision relied on grouping of large clinical and pathological data. Due to this complication, the interest increased in a significant amount between the researchers and clinical professionals about the efficient and accurate heart disease prediction. In case of heart disease, the correct diagnosis in early stage is important as time is the very important factor. Heart disease is the principal source of deaths widespread, and the prediction of Heart Disease is significant at an untimely phase. Machine learning in recent years has been the evolving, reliable and supporting tools in medical domain and has provided the greatest support for predicting disease with correct case of training and testing. The main idea behind this work is to study diverse prediction models for the heart disease and selecting important heart disease feature using genetic algorithm. The optimized prediction models using genetic algorithm performance is better than traditional prediction models. The performances of the different prediction models retested with different heart disease data sets and validated with real-time data sets. International Journal of Pure and Applied Mathematics Volume 119 No. 16 2018, 5323-5336 ISSN: 1314-3395 (on-line version) url: http://www.acadpubl. eu/hub/ Special Issue http://www.acadpubl. eu/hub/