Miracle-dz/UniFAR-FTUs huggingface dataset:
Computational reasoning over radiopropagation models and their formulations

Semantic frameworks are more and more used to access knowledge and to enhance cooperation in scientific research. An increasing need of resource sharing and integration is coming out in the electromagnetic domain as well. This paper provides a proposal for an electromagnetic ontology framework, designed with the objective of maximizing knowledge reusability and integrability. It follows a modular, layered architecture, based on a robust sharable conceptualization, given by publicly available well-known top-level ontologies. The implementation of an ontology in the area of radiopropagation modeling is provided as specific example of practical application. Finally, the paper illustrates a simple example of reasoning, which demonstrates how the ontology supports advanced knowledge processing by simple query codification.
ENFORMASYON TOPLUMUNDA EĞİTİMİN YERİ

Cagimizin gelismis toplum yapisi, enformasyon toplumu olarak nitelendirilmektedir. Teknolojik ve bilimsel gelisme, hizli degisim ve donusum ozellikleri tasiyan enformasyon toplumu, sanayi toplumundan farkli paradigmalara dayanmaktadir. Gunumuzun yukselen degerleri olan bilimsel bilgi, teknolojik gelisme ve hizli degisim, formal egitimin onemini artirmaktadir. Bireyin bu toplumsal asamada arzu ettigi sekilde yasayabilmesi, gecmisten daha fazla bilgi donanimina sahip olmasina baglidir. Bu nedenle, bireysel ve toplumsal yasami dogrudan etkileyen surec olarak egitime buyuk roller dusmektedir. Bireyi ekonomik ve sosyal hayata hazirlayan kurum olan egitimin uzerine aldigi islevleri yerine getirebilmesi icin dunyadaki gelismeleri dikkate almasi, kendini teknolojik ve bilimsel degismelere uyarlamasi gerekir. Nitekim, gunumuzun guclu ekonomik ve sosyal yasantisina sahip ulkeler, tum kazanimlarini egitime verdikleri onem ve egitim kurumlarini gunun kosullarina gore yeniden yapilandirmalarina borcludurlar. Konuyu teorik acidan degerlendiren bu calisma, enformasyon toplumunun ozelliklerini aciklayarak, enformasyon toplumunda egitimin yeri ve onemi hakkinda bir saptama yapmak amacini tasimaktadir.
Incipient stator fault detector based on neural networks end symmetrical components analysis for induction motor drives

In this paper a computer system for monitoring and diagnostics of the stator windings of the induction motor fed from the frequencies converter is presented. A possibility of stator faults detection using a neural-network detector, possibly at the early stage of the damage, is checked. The experimental research was carried out for a small power induction motor, with different levels of the stator failures (special motor design allowed to test short circuits in each phase of the motor), load torque and converter frequencies. The measurement of stator phase currents, phase-to-phase voltages and their transformation to symmetrical components are used in stator winding condition monitoring. For diagnostic purposes, the Multi-Layer Perceptron (MLP) neural detectors are developed. Preliminary research of the neural network response (offline) showed that the neural networks with simple internal structure, used for the fault level detection, give satisfactory results, that is very important in practical realization. The designed detector was implemented in LabVIEW and tested during the operation of the machine (online).
Tetralogy of Fallot with coronary artery to pulmonary artery fistula

Department of Obstetrics and Gynecology, Sint-Jans Hospital, Genk, Belgium Center for Human Genetics, University of Leuven, Leuven, Belgium GROW School of Oncology and Developmental Biology, Maastricht University Medical Centre+, Maastricht, The Netherlands Department of Clinical Genetics, Maastricht University Medical Center+, Maastricht, The Netherlands Department of Pathology, Maastricht University Medical Center+, Maastricht, The Netherlands *Correspondence to: Ingrid Witters. E-mail: Ingrid.witters@skynet.be
Edge computing meets millimeter-wave enabled VR: Paving the way to cutting the cord

In this paper, a novel proactive computing and mmWave communication for ultra-reliable and low latency wireless virtual reality (VR is proposed. By leveraging information about users' poses, proactive computing and caching are used to pre-compute and store users' HD video frames to minimize the computing latency. Furthermore, multi-connectivity is exploited to ensure reliable mmWave links to deliver users' requested HD frames. The performance of the proposed approach is validated on a VR network serving an interactive gaming arcade, where dynamic and real-time rendering of HD video frames is needed and impulse actions of different players impact the content to be shown. Simulation results show significant gains of up to 30% reduction in end-to-end delay and 50% in the 90th percentile communication delay.
Staphylococcal Superantigen-Like Protein 3 Binds to the Toll-Like Receptor 2 Extracellular Domain and Inhibits Cytokine Production Induced by Staphylococcus aureus, Cell Wall Component, or Lipopeptides in Murine Macrophages

ABSTRACT Staphylococcal superantigen-like proteins (SSLs) are a family of exoproteins sharing structural similarity with superantigens, but no superantigenic activity. Corresponding host target proteins or receptors against a portion of SSLs in the family have been identified. In this study, we show that SSL3 specifically binds to Toll-like receptor 2 (TLR2) and inhibits the stimulation of macrophages by TLR2 ligands. An approximately 100-kDa protein was recovered by using recombinant His-tagged SSL3-conjugated Sepharose from the lysate of porcine spleen, and the protein was identified as porcine TLR2 by peptide mass fingerprinting analysis. The SSL3-conjugated Sepharose recovered human and mouse TLR2 but not TLR4 from human neutrophils and mouse macrophage RAW 264.7 cells, as well as a recombinant TLR2 extracellular domain chimera protein. The production levels of interleukin 12 (IL-12) from mouse macrophages treated with heat-killed Staphylococcus aureus and of tumor necrosis factor alpha (TNF-α) from RAW 264.7 cells induced by peptidoglycan or lipopeptide TLR2 ligands were strongly suppressed in the presence of SSL3. The mutation of consensus sialic acid-containing glycan-binding residues in SSL3 did not abrogate the binding ability to TLR2 or inhibitory activity on TLR2, indicating that the interaction of SSL3 with TLR2 was independent of the sialic acid-containing glycan-binding residues. These findings demonstrate that SSL3 is able to bind the extracellular domain of TLR2 and interfere with TLR2 function. The present study provides a novel mechanism of SSL3 in immune evasion of S. aureus via interfering with its recognition by innate immune cells.
Role of p 53 in Regulating Constitutive and X-Radiation-Inducible CD 95 Expression and Function in Carcinoma Cells 1

The p53 tumor suppressor protein is known to regulate the expression of the CD95 (Fas/APO-1) death receptor in a small subset of normal cell types as well as in many cancer cell types. However, whether p53-dependent regulation of CD95 expression is consistently associated with increased susceptibility to CD95-mediated cell death is poorly understood. To address this issue, we examined constitutive and induced CD95 surface expression and function in wild-type p53-expressing carcinoma cells relative to their isogenic p53-inactivated counterparts. We compared HCT116 colorectal carcinoma cells with their p53 biallelic knock-outs and control-transfected MCF-7 breast carcinoma cells with MCF-7 cells expressing a miniprotein inhibitor of p53 (p53DD). In both cell lines, the constitutive expression of surface CD95 was significantly reduced in p53inactivated cells, as was the apoptotic response to agonistic anti-CD95 antibody. In both cell lines, only cells with wild-type p53 activity exhibited up-regulation of surface CD95 after ionizing irradiation. Interestingly, induction of CD95 expression substantially enhanced the apoptotic response to CD95 ligation only in MCF-7 cells but not in HCT116 cells. These findings provide direct evidence for a major role for wild-type p53 activity in regulating constitutive expression and function of CD95 in carcinoma cells; however, they also demonstrate that the functional effect of DNA damage-induced up-regulation of CD95 may be cell type specific.
Immunogold labelling to localize polyphenol oxidase (PPO) during wilting of red clover leaf tissue and the effect of removing cellular matrices on PPO protection of glycerol-based lipid in the rumen.

BACKGROUND The enzyme polyphenol oxidase (PPO) reduces the extent of proteolysis and lipolysis within red clover fed to ruminants. PPO catalyses the conversion of phenols to quinones, which can react with nucleophilic cellular constituents (e.g. proteins) forming protein-phenol complexes that may reduce protein solubility, bioavailability to rumen microbes and deactivate plant enzymes. In this study, we localized PPO in red clover leaf tissue by immunogold labelling and investigated whether red clover lipid was protected in the absence of PPO-induced protein-phenol complexes and plant enzymes (lipases). RESULTS PPO protein was detected to a greater extent (P < 0.001) within the chloroplasts of mesophyll cells in stressed (cut/crushed and wilted for 1 h) than freshly cut leaves for both palisade (61.6 and 25.6 Au label per chloroplast, respectively) and spongy mesophyll cells (94.5 and 40.6 Au label per chloroplast, respectively). Hydrolysis of lipid and C18 polyunsaturated fatty acid biohydrogenation during in vitro batch culture was lower (P < 0.05) for wild-type red clover than for red clover with PPO expression reduced to undetectable levels but only when cellular matrices containing protein-phenol complexes were present. CONCLUSION Damaging of the leaves resulted in over a doubling of PPO detected within mesophyll cells, potentially as a consequence of conversion of the enzyme from latent to active form. PPO reduction of microbial lipolysis was apparent in macerated red clover tissue but not in the absence of the proteinaceous cellular matrix, suggesting that the PPO mechanism for reducing lipolysis may be primarily through the entrapment of lipid within protein-phenol complexes.
Antihepatotoxic actions of flavonolignans from Silybum marianum fruits.

The antihepatatoxic effects of flavonolignans and related constituents from SILYBUM MARIANUM were examined using carbon tetrachloride- and galactosamine-induced cytotoxicity in primary cultured rat hepatocytes as model systems. Remarkable inhibitory actions were observed with silandrin, 3-deoxysilychristin, silybin and silymonin in carbon tetrachloride-treated cultures, and silydianin and silymonin were effective in preventing galactosamine-produced cell lesions. Possible structure-activity relationships are discussed.
Interference alignment for overlay cognitive radio based on game theory

In cognitive radio (CR), interference alignment (IA) is an effective approach to eliminate the interference of secondary users (SUs). Thus, SUs can share the spectrum with primary users (PUs). In this paper, IA for overlay CR is discussed, and a time resource auction scheme based on game theory is proposed, which uses the given related equilibrium functions to balance the benefits of PU and SUs, meanwhile the time resource can be reasonably distributed. Simulation results are presented to show the effectiveness of the proposed scheme.
Overlapping roles for the histone acetyltransferase activities of SAGA and Elongator in vivo

Elp3 and Gcn5 are histone acetyltransferases (HATs) that function in transcription as subunits of Elongator and SAGA/ADA, respectively. Here we show that mutations that impair the in vitro HAT activity of Elp3 confer typical elp phenotypes such as temperature sensitivity. Combining an elp3Δ mutation with histone H3 or H4 tail mutations confers lethality or sickness, supporting a role for Elongator in chromatin remodelling in vivo. gcn5Δelp3Δ double mutants display a number of severe phenotypes, and similar phenotypes result from combining the elp mutation with mutation in a gene encoding a SAGA‐specific, but not an ADA‐specific subunit, indicating that Elongator functionally overlaps with SAGA. Because concomitant active site alterations in Elp3 and Gcn5 are sufficient to confer severe phenotypes, the redundancy must be specifically related to the HAT activity of these complexes. In support of this conclusion, gcn5Δelp3Δ phenotypes are suppressed by concomitant mutation of the HDA1 and HOS2 histone deacetylases. Our results demonstrate functional redundancy among transcription‐associated HAT and deacetylase activities, and indicate the importance of a fine‐tuned acetylation–deacetylation balance during transcription in vivo.
Surfactant protein A down-regulates epidermal growth factor receptor by mechanisms different from those of surfactant protein D

We recently reported that the lectin surfactant protein D (SP-D) suppresses epidermal growth factor receptor (EGFR) signaling by interfering with ligand binding to EGFR through an interaction between the carbohydrate-recognition domain (CRD) of SP-D and N-glycans of EGFR. Here, we report that surfactant protein A (SP-A) also suppresses EGF signaling in A549 human lung adenocarcinoma cells and in CHOK1 cells stably expressing human EGFR and that SP-A inhibits the proliferation and motility of the A549 cells. Results with 125I-EGF indicated that SP-A interferes with EGF binding to EGFR, and a ligand blot analysis suggested that SP-A binds EGFR in A549 cells. We also found that SP-A directly binds the recombinant extracellular domain of EGFR (soluble EGFR or sEGFR), and this binding, unlike that of SP-D, was not blocked by EDTA, excess mannose, or peptide:N-glycosidase F treatment. We prepared a collagenase-resistant fragment (CRF) of SP-A, consisting of CRD plus the neck domain of SP-A, and observed that CRF directly binds sEGFR but does not suppress EGF-induced phosphorylation of EGFR in or proliferation of A549 cells. These results indicated that SP-A binds EGFR and down-regulates EGF signaling by inhibiting ligand binding to EGFR as well as SP-D. However, unlike for SP-D, SP-A lectin activity and EGFR N-glycans were not involved in the interaction between SP-A and EGFR. Furthermore, our results suggested that oligomerization of SP-A is necessary to suppress the effects of SP-A on EGF signaling.
The thermal stratification of the extratropical troposphere

This chapter discusses the dynamical mechanisms responsible for the maintenance and variability of the extratropical thermal stratification and tropopause in the zonal mean. Figure 3.1 shows the zonal-mean temperature lapse rate of Earth’s atmosphere for boreal winter and summer. The zonal-mean lapse rate in the free troposphere is relatively uniform (about 6.5 K km^(−1) ) and varies only weakly with season — observations that motivated the assumption of a fixed thermal stratification in quasigeostrophic theory. Regions of smaller lapse rate (statically more stable stratification) are seen near the surface in the subtropics and in high latitudes, particularly in winter. At the tropopause, the lapse rate decreases, in many regions to zero or less, marking the transition from the troposphere to the more stably stratified stratosphere.
On outage probability and channel capacity for the Nth best opportunistic ADF relay systems

In this paper, we derive an exact outage probability and average channel capacity for the Nth best opportunistic adaptive decode-and-forward (OADF) relay systems over Rayleigh fading channels. Based on error-events at relay nodes, the Nth best relay's selection probability is expressed as a form with the specified multiple summations and the specified length of each summation. Then, exact performance metrics are obtained as well-known closed-forms. Simulation results are finally presented to validate that the derived analytical expressions are general solutions to cover all Rayleigh fading channel conditions.
Design of virtual stiffness for human operated robot considering external force in safety enhancement

Precise force control and position control is essential for many robotic applications. During unilateral or bilateral object handling remote applications, human operators apply excess forces on the actuators with the intention of better grip and it is possible to damage the handled objects. This paper proposes position control and force control techniques when human applies excess force. The controllers consist of predefined force and equilibrium position which are correspond to remote environmental object safety. The operator applied excess force is modeled as a spring force through a virtual stiffness model. The paper introduces proportional derivative position control loop to conventional virtual stiffness controller. The force control loop and the position control loop references are combined in the common dimension of acceleration to produce current reference to the actuator. The sensorless sensing techniques of disturbance observer and reaction force observer are utilized to disturbance suppression and external force estimation. In the force controller, estimated reaction force is reduced to desired value by introducing virtual force loop between reaction force observer output and reaction force feedback input. The position control is achieved by introducing a scaling factor to reaction force feedback path. The switching between force control and position control is possible with scaling factor value. The performances of proposed methods are compared with conventional method and validity of the proposed methods is verified by simulations and experiments.
The applications of NSOM/QDs-based single-molecule in situ detection on cell membrane

Near-field scanning optical microscopy (NSOM) has been proved to be a useful nanotechnology tool for studying materials due to its highest optical resolution to break through the diffraction limit, but its applications in biomedical research are still limited. With the development of biology, medicine and chemistry,the methods to study life science in single molecule level are required. The high optical resolution property makes NSOM an ideal tool to study cellular ultrastructure, function, single biomolecule distribution and even the relationship of biomolecules on cell membrane. But the complicated natures of cell membranes or biologic molecules and the restriction of conventional organic fluorophores (low luminescence and photostability) make it hard for NSOM to generate high spatial resolution images. The development of quantum dots (QDs) overcome these technological barriers successfully. The combination of NSOM and QDs is recognized as a fascinating technology to study cell biology in single molecule level without injurying biological samples. In this chapter, we will introduce the basic principles of NSOM/ QDs method, the recent advances of NSOM/QDs in single-molecule in situ detection on cell membrane and make an outlook on their application prospects.
Participatory Mapping of Occupational Hazards and Disease among Asbestos-exposed Workers from a Foundry and Insulation Complex in Canada

Abstract A study of former asbestos-exposed foundry and insulation workers was carried out in Sarnia, Ontario, home to Canada's petrochemical industry, using participatory mapping to document past exposures and subsequent diseases. Before it closed, government inspectors had monitored the use of asbestos at the facility, documenting levels that were thousands of times above the current legal limit. The study was undertaken by the Occupational Health Clinics for Ontario Workers (OHCOW) and Canadian Auto Workers (CAW) to provide evidence for worker compensation claims. Using facilitated hazard mapping, former Holmes workers graphically reconstructed their workplaces and detailed their exposures. Using facilitated body mapping, workers recorded and displayed their health problems. The study uncovered a grim pattern of occupational diseases. Following the release of the results, coupled with clinically confirmed diagnoses and corroborating evidence of exposure, hundreds of former Holmes employees and their families received compensation for occupational diseases that had previously gone unrecognized.
Spectral holography of shaped femtosecond pulses.

Storage and subsequent recall of shaped femtosecond waveforms is achieved by performing spectral holography within a femtosecond pulse-shaping apparatus. Readout of the spectral hologram by using a short reference pulse yields both real and time-reversed reconstructions of the original signal. Convolution and correlation operations are achieved by using shaped pulses for readout. These experiments demonstrate the possibility of nonlinear spectral filtering and signal processing of femtosecond optical waveforms.
A 2.4-GHz RF sampling receiver front-end in 0.18-/spl mu/m CMOS

This paper presents an integrable RF sampling receiver front-end architecture, based on a switched-capacitor (SC) RF sampling downconversion (RFSD) filter, for WLAN applications in a 2.4-GHz band. The RFSD filter test chip is fabricated in a 0.18-/spl mu/m CMOS technology and the measurement results show a successful realization of RF sampling, quadrature downconversion, tunable anti-alias filtering, downconversion to baseband, and decimation of the sampling rate. By changing the input sampling rate, the RFSD filter can be tuned to different RF channels. A maximum input sampling rate of 1072 MS/s has been achieved. A single-phase clock is used for the quadrature downconversion and the bandpass operation is realized by a 23-tap FIR filter. The RFSD filter has an IIP/sub 3/ of +5.5 dBm, a gain of -1 dB, and more than 17 dB rejection of alias bands. The measured image rejection is 59 dB and the sampling clock jitter is 0.64 ps. The test chip consumes 47 mW in the analog part and 40 mW in the digital part. It occupies an area of 1 mm/sup 2/.
Regional aspects of modelling burned areas in Europe

This paper presents a series of improvements to the quantitative modelling of burned areas in Europe under historical climate. The Standalone Fire Model (SFM) based on a state-of-the-art large scale mechanistic fire modelling algorithm is used to reproduce historical burned areas reported in the two publicly available datasets – European Forest Fire Information System (EFFIS) and Global Fire Emissions Database (GFED). The most recent versions of these sources allow a broader validation of SFM’s modelled burned areas at a country level. Our analysis is carried out for the years 2000–2008 for 17 European countries utilising both EFFIS and GFED datasets for model benchmarking. We suggest improving the original model by modifying the fire probability function reflecting fuel moisture. This modification allows for a dramatic improvement of accuracy in modelled burned areas for a range of European countries. We also explore in detail a pixel-level parametrisation of firefighting efficiency in SFM along with modifications of the biomass map. In comparison with the aggregated country-level approach, the advantages of the finer calibration are quite minor for the most recent version of the GFED dataset. Overall, the annual burned areas modelled by this improved SFM version are in good agreement with historical observations.
The Electron-Hole Bilayer TFET: Dimensionality Effects and Optimization

An extensive parameter analysis is performed on the electron-hole bilayer tunnel field-effect transistor (EHBTFET) using a 1-D effective mass Schrödinger-Poisson solver with corrections for band non-parabolicity considering thin InAs, In<sub>0.53</sub>Ga<sub>0.47</sub>As, Ge, Si<sub>0.5</sub>Ge<sub>0.5</sub>, and Si films. It is found that depending on the channel material and channel thickness, the EHBTFET can operate either as a 2-D-2-D or 3-D-3-D tunneling device. InAs offers the highest I<sub>ON</sub>, whereas for the Si and Si<sub>0.5</sub>Ge<sub>0.5</sub> EHBTFETs, significant current levels cannot be achieved within a reasonable voltage range. The general trends are explained through an analytical model that shows close agreement with the numerical results.