Miracle-dz/UniFAR-FTUs huggingface dataset:
The hepatoprotective effect of Cheral as anti-oxidant and anti-inflammation on mice (Mus musculus) with breast cancer

Introduction: Recent studies have reported that breast cancer may affect the physiology of other organs, including oxidative stress in the liver. On the other hand, some agents such as white turmeric (Curcuma longa) and Meniran (Phyllanthus niruri) seem to maintain redox stability and immunomodulation. Both of them are combined into Cheral potion. This study was aimed to investigate the Cheral efficacy in modulating oxidative stress based on Nuclear factor erythroid 2-related factor 2 (Nrf2), HEME OXIGenase (HO), and superoxide dismutase (SOD) levels as well as pro-inflammatory cytokines under breast cancer condition in vivo. Methods: Nrf2, HO, and SOD from hepatocytes, and tumor necrosis factor-α (TNF-α) and interferon-γ (IFN-γ) from splenocytes were measured by flow cytometry after 14 days of Cheral administration. Results: The results showed that mice model for breast cancer underwent oxidative stress denoted by high levels of HO, and SOD accompanied by increased levels of TNF-α and IFN-γ in the cancer group compared to normal healthy group (P<0.05). In contrast, Cheral treatment was able to modulate redox balance by declining levels of HO, SOD, TNF-α, and IFN-γ, but not Nrf2, compared to cancer group (P<0.05). Conclusion: The results showed that breast cancer could alter the host’s physiology, including liver oxidative stress. The levels of TNF-α and IFN-γ might contribute to regulation of redox balance in the liver. However, Cheral has potency as an alternative therapeutic agent to reduce oxidative stress in the liver under breast cancer condition.
Whither QSAR?

Introduction: Acute myocardial infarction (MI) indicates irreversible myocardial injury resulting in necrosis of a significant portion of myocardium. MI is associated with high mortality. The difference between the signs of MI in each gender is unclear. The aim of this study was to describe gender-associated differences in symptom presentation after acute MI. Methods: This analytic-descriptive research was carried out on 102 patients (44 women and 58 men) with MI experience who referring in Shahid Mohamadi hospital and Abolfazl hospital, Hormozgan, Iran. Patients participating in the study were randomly selected. Individual information; the pain characteristics records, electrocardiogram and laboratory results, pain numerical rating scale, were collected. Results: The results showed that chest pain was the most common initial symptom in both men and women (92%) This is while sweating in men (74%) and dyspnea in women (61.4) as the second reported sign. No gender-related differences in other symptoms such as vomiting, nausea, dizziness, palpitations, pallor, epigastric pain, chills and weakness were observed. Conclusion: In this study in patients with MI, women had a worse-risk profile in comparison to men. No significant gender-related differences in symptoms were observed.
Active Link Inference for Case Building Investigation

How can we infer connections between entities, given the evidences of their 1 relations? How can we help an investigator to ﬁnd salient patterns by connecting 2 the dots more efﬁciently? For example in combating online human trafﬁcking, 3 connecting the related escort advertisements outlines an organized activity, which 4 is the ﬁrst step to identify the target who is advertising the victims. This paper 5 presents a principled way of inferring links where the user is able to actively 6 provide feedback and guide the inference. We show how our method helps an 7 investigator to ﬁnd related entities to an initial lead and explains why they are 8 related, when mining millions of escort advertisements posted in one of the largest 9 classiﬁed advertising websites. As an active link inference method, our proposal 10 has broad applications wherever the connections between entities are not given a 11 priori, in particular for mapping out the covert web of entities in fraud detection 12 and counterterrorism. 13
YI-HSUN CHEN_NCL Full Paper_ On the (A)Telicity of Verb-Adjective Compounds in Mandarin

This paper examines the aspectual properties of the “degree achievements” verbs in Mandarin, and indicates that degree achievements (henceforth DAs) in Mandarin also reveal the variability in (a)telicity. Further more, following the previous works on DAs in English (Hay, Kennedy and Levin (1999), Kear ns (2005) and Winter (2006) and Kennedy & Levin (2008)), we suggest that the sc ale structure of adjectives significantly contributes to the determination of ( a)telicity of degree achievement verbs in Mandarin as well. Finally, based on the da ta in Chinese, we propose that a telic DA denotes “become maximally A” rather than “ become A”, which cross-linguistically supports the study of Kennedy & Levin (2008), while contradicts that of Kearns (2005) and Winter (2006).
TiO2 Nanoparticles Decorated Graphene Nanoribbons for Voltammetric Determination of an Anti-HIV Drug Nevirapine

In the present study, electrochemical behavior of nevirapine on a glassy carbon electrode (GCE) modified with TiO2 nanoparticles decorated graphene nanoribbons was investigated. Characterization of different components used for modifications was achieved using Fourier transform infrared spectroscopy (FT-IR) and scanning electron microscopy (SEM). The electrochemical behavior of nevirapine on the modified electrodes was examined using cyclic voltammetry (CV), electrochemical impedance spectroscopy (EIS), chronoamperometry (CA), and differential pulse voltammetry (DPV). A considerable oxidation potential decrease of +352 mV for nevirapine in 0.1 M phosphate-buffered saline (PBS), pH 11.0, was achieved due to synergy offered by graphene nanoribbons and TiO2 compared to graphene nanoribbons (+252 mV) and TiO2 (−37 mV), all with respect to the glassy carbon electrode. Under optimized conditions, DPV gave linear calibrations over the range of 0.020–0.14 µM. The detection limit was calculated as 0.043 µM. The developed sensor was used for determination of nevirapine in a pharmaceutical formulation successfully.
Attract & Kill technique against Lobesia botrana Den.&Schiff. (Lepidoptera: Tortricidae) in Romania 62 ATTRACT & KILL TECHNIQUE AGAINST LOBESIA BOTRANA DEN.&SCHIFF. (LEPIDOPTERA: TORTRICIDAE) IN ROMANIA

This paper presents the results of the studies carried out during 2006-07 in 3 vineyards situated in the representative wine growing centres of Romania (Research Development Institute for Viticulture Valea Calugareasca situated in middle of the country, Research Development Station for Viticulture Murfatlar in the South-Eastern and Research Development Station for Viticulture Iasi in Eastern part of the country) with a product PRELUDIU LB used in Attract & Kill technique. The product, obtained by Research Institute for Chemistry "Raluca Ripan" ClujNapoca, consists of a viscous formulation containing specific grapevine moth (Lobesia botrana) pheromone (E-9-dodecenylacetate and E,Z-7,9-dodecadienyl acetate) and a pyrethroid. The formulation was applied uniformly on the branches of the vines, by hand (400g/ha), 1-2 time in the season, depending of the infestation level. The efficacy of a Romanian product PRELUDIU LB was ranging between 61.20-81.37% in the two years study; the losses of the yield were reduced with 25-33%. The results of this strategy show that it can compete with conventional spray applications and is therefore a good alternative for grapevine moth control in integrated wine growing.
On the morpho-semantic puzzle of superlative modifiers

Superlative modifiers (SMs) such as English at least and at most have posed a longstanding and intriguing morpho-semantic puzzle: Why do SMs morphologically involve a quantity adjective and the superlative morpheme? What is the role of quantity adjective and superlative morpheme inside SMs? How are these morphological pieces connected with the semantics of SMs? Below, the relevant facts in English are illustrated in (1) and (2), where the same morphological components least and most are involved in both SMs and QSs. 1
An affine equivariant anamorphosis for compositional data

For the geostatistical treatment of compositional data it s common to trnsform the data to logratios. Several logratio transformations are available and invariance of the results under the choice of logratio transform is desirable, but this is not automatically satisfied for geostatistical simulation where it is common that the data are first mapped to Gaussian space. The usual method, the normal score transform, is not independent of the choice of logratio nor are the transformed data multivariate normal. In this contribution a method is proposed based on an affine-equivariant kernel density estimation, which is then continuously deformed to a multivariate standard normal distribution. The anamorphosis is achieved via the co-deformation of the underlying space. The method is illustrated and compared with existing alternatives using a case study from a Westaustralian iron ore mining operation.
Assessment of the Phytochemicals Proximate and Elemental Composition of the Fruits of Dialium guineese (Icheku)

Phytochemical, proximate and elemental analyses of the fruits (pulp) of Dialium guineese were carried out using standard analytical techniques. Phytochemical analysis of the water, methanol and ethyl acetate extracts showed the presence of alkaloids, tannins, saponins and flavonoids in various concentrations while glycoside and phenol were conspicuously absent. Proximate analysis of the fruits indicated the presence of protein (8.4%), carbohydrates (78.69%), Moisture (4.1%), crude fibre (0.8%), fat (4.8%) and ash (3.2%). The results of the selected vitamin analysis showed the presence of vitamin C (7.1%) and Vitamin A (0.03%) while the results of the trace mineral elements showed the presence of Ca (45.0g/100g), Zn (0.7g/100g), Cr (1.5g/100g), Fe (4.1g/100g) while Pb was impressively and notably absent, showing the overall safety and health benefit of this plant part.
Evaluation of CD4 Cell Progression Among HIV Infected Children Initiating ART: A Case of Adama Referral Hospital and Medical College, Ethiopia

Human immune deficiency virus (HIV) is a major cause of infant and childhood mortality and morbidity; without treatment about 50% of them will succumb to HIV/AIDS before the age of two years. HIV infected children should start ART in order to reduce AIDS related morbidity and mortality, or to improve their survival time. Effective therapies and reduced AIDS related morbidity and mortality have shifted the focus in pediatric human immune deﬁciency virus (HIV) from minimizing short-term disease progression to maintaining optimal long-term health. The main purpose of this study was to evaluate the predictors of longitudinal CD4 cell progression of HIV infected children who were under ART. The study considered a cohort of 201 HIV infected children who were aged 15 years or younger and those were on ART from October 1, 2013 to March 30, 2017 at Adama Referral Hospital and Medical College. To analyze the data we employed exploratory data analysis and linear mixed effect model. The result from linear mixed effect model reviled that observation time, age, WHO clinical stage, history of TB, and functional status had significantly associated with mean change in the square root of CD4 cell count, and they are the predictor of longitudinal CD4 cell change.
INSTITUTE OF MATHEMATICS of the Polish Academy of Sciences

Pairing-friendly elliptic curves have the rare property that the Weil or Tate pairing on points of some large prime order can be eﬃciently computed. Thanks to this they are useful in cryptography for implementing protocols based on these pairings. To construct ordinary pairing-friendly curves one usually obtains parameters of a curve as values of certain polynomials, and then ﬁnds its equation via the complex multiplication method. Such polynomials are called families. There is essentially one general method for constructing the so-called complete families, which in the fullest generality is due to Brezing and Weng. No general methods have been proposed for constructing (i) arbitrary families, and (ii) families of curves of nearly prime group order. In this paper we propose two methods for the ﬁrst purpose, which extend the Brezing-Weng method and the Dupont-Enge-Morain method for constructing individual pairing-friendly curves. Furthermore, we describe all arbitrary families ( r ( x ) ,t ( x ) ,q ( x )) with embedding degree k satisfying (ii) for which Q [ x ] / ( r ( x )) ∼ = K , where K is a ﬁxed number ﬁeld containing k th roots of unity (in fact, we describe families with parameter ρ ≤ ρ 0 for a given bound 1 ≤ ρ 0 < 2). This allows one to represent such families by rational solutions of certain systems of polynomial equations.
Automatic Circuit Layout for Emerging Nanoscale Architectures

—The problem of automatic circuit layout is a difﬁcult problem since there is a huge number of devices and there are many physical constraints to be met. Nowadays with the aparition of nanoscale devices, the problem becomes even more complicated, due to the huge integration densities of such devices and to the high percentage of defects due to the bottom-up assembly process. In this context we propose an evolutive, generic CAD framework, able to compute circuit layouts for a large number of novel fabric architectures.
Functional Groups Determination and Antimicrobial Activity of Isolated Compound from Alternanthera sessilis(L.)D.C

In this research, one Myanmar indigenous medicinal plant, namely Alternanthera sessilis was chosen for preliminary phytochemical screening and antimicrobial activity tests.The whole plant of Alternanthera sessilis gives positive test for alkaloid, flavonoid and phenolic tests. Moreover, the antimicrobial activities of the whole plant of Alternanthera sessilis was tested by Agar-well diffusion method on six tested organisms such as Bacillus subtilis, Staphylococus aureus, Pseudomonas aeruginosa, Bacillus pumilus, Candida albicans and Mycobacterium species respectively. Ethyl acetate extract of the whole plant of Alternanthera sessilis responds medium activity on five selected organisms such as Staphylococcus aureus, Pseudomonas aeruginosa, Bacillus pumilus, Candida albicans and Mycobacterium species. Furthermore, the dark green colour amorphous compound (4.4 mg, 0.147%) could be isolated from the whole plant of Alternanthera sessilis by using advanced separation methods such as Thin Layer and Column Chromatography. The functional groups present in isolated compound were identified by FT-IR (Fourier Transform Infrared Spectroscopy)spectral data. This pure compound is rechecked for antimicrobial activities using Agar-well diffusion method. Pure compound has low activity on Staphylococcus aureus, Pseudomonas aeruginosa and Candida albicans respectively.
rbcL GENE SEQUENCING AND RANDOM AMPLIFIED POLYMORPHIC DNA (RAPD) PROFILING OF Pavonia senegalensis (CAV.) LIESTNER (MALVACEAE) A MEDICINAL PLANT COLLECTED FROM GIWA NORTHWEST NIGERIA

Pavonia senegalensis (Cav.) Liestner is a medicinal plant used in African traditional medicine for the treatment of diarrhea, soft and tissue infections, induction of labor and contraception. In this study, ribulose-1, 5-biphosphate carboxylase (rbcL)gene sequence and random amplification of polymorphic DNA (RAPD) profile of the plant were determined. The study showed that the species of the plant is phylogenetically related to Abutilon sp. , Hibiscus micranthus, Hibiscus punalunensis, Hibiscus rosa-sinensis and Lagunaria patersonia all from the same family showing 98% similarity on the basis of rbcL gene sequences. The studied specimen and related taxa inferred from partial rbcL gene sequence demonstrated a distinct lineage; therefore, could distinguish the species as P. senegalensis without doubt. RAPD profile of P. senegalensis generated amplified products ranging from 320 to 700 bp. A total of 9 bands were observed for the plant species using 3 primers (OP-A07, OP-A10 and OP-C06). The determined rbcL gene sequence and RAPD profile of the P. senegalensis will help in quality control for authentication and detection of adulteration in the development of the plant as an herbal medicine.
To Tolerate or not Tolerate Bribery: Can a Lack of Control over Corruption Determine Tolerance Levels?

Most of the research on corruption has either focused on the impact corruption has on economic growth, development, and investment, or the implications of corruption on governance. However, limited research has focused on the relationship between government control of corruption and individual-level acceptance of bribery within society. This study uses the World Values Survey and other observed data from a total of 55 countries to test whether high levels of corruption cause individuals to be more accepting of bribery among public officials. A Generalized Least Square Model was applied to test the effect of government corruption on control and individual-level tolerance for bribery between 1996 and 2015.
Overeducation and workers’ heterogeneity: is overeducation a real phenomenon in the Spanish labor market?

This paper analyzes the economic effects of overeducation in the Spanish labor market by relaxing the assumption of homogeneous workers within the same educational level. Only workers with a higher education level are considered, differentiating between properly educated and overeducated workers. Moreover, a distinction is made between real and apparent overeducation. The PIAAC database is used and different methods are employed to measure educational mismatch and to differentiate between real and apparent overeducation. Among the obtained results it is found that most of the workers with a higher education level who appear to be overeducated in the Spanish labor market could in fact be considered as only apparently overeducated, being the wage penalty associated to this educational mismatch lower than the wage penalty suffered by real overeducated workers. Different returns to educational mismatch found for each group of overeducated individuals point hence to the need of taking account of worker’s heterogeneity within educational levels when analyzing the returns to education and to educational mismatch.
The Signaling Pathways, and Therapeutic Targets of Antiviral Agents: Focusing on the Antiviral Approaches and Clinical Perspectives of Anthocyanins (apple seeds) in the Management of Viral Diseases like Corona

 1Department of Pharmacognosy, School of Pharmacy and Pharmaceutical Sciences, Isfahan University of Medical Sciences, Isfahan, Iran  2Pharmaceutical Sciences Research Center, Health Institute, Kermanshah University of Medical Sciences, Kermanshah, Iran  3Isfahan Cardiovascular Research Center, Cardiovascular Research Institute, Isfahan University of Medical Sciences, Isfahan, Iran  4Departamento de Ciencias del Ambiente, Facultad de Química y Biología, Universidad de Santiago de Chile, Santiago, Chile
Electromagnetic Field Generated by Wireless Alarm Devices

— Together with the rise of importance of devices employing wireless networks based on the principle of radio frequency data transfers, also the discussion on harmfulness of the electromagnetic radiation has occurred. The authors of this paper obviously cannot provide unambiguous answers to stop this discussion. On the other way, they can provide the reader of this paper with real data obtained by measurements processed inside a semi anechoic chamber that were performed at several wireless alarm peripherals. The measured values are compared to the technical and hygienic standards so the reader can form an idea of the amount of the radiated energy. Moreover, examples of waterfall diagrams of spectra generated by the devices are also listed in this paper.
First record of the invasive woolly whitefly Aleurothrixus floccosus (Maskell) from India

Occurrence of the highly polyphagous woolly whitefly, Aleurothrixus floccosus (Maskell) (Hemiptera: Aleyrodidae) on guava (Psidium guajava L.) was recorded as invasive in India. The whitefly is believed to be neotropical origin but is now found throughout the warmer parts of the world. The identification of A. floccosus was done through taxonomic morphological characters of puparium and reconfirmed by DNA barcoding of adult whitefly using partial (658 bp) mitochondrial cytochrome oxidase 1 (CO1) gene. This is the first report of the breeding of A. floccosus on guava in India. Identification details, diagnosis, symptoms of damage and impact of its infestation on guava and citrus are discussed.
Improving the quality of Education at Rural Schools in Namibia

Schools in rural areas are faced by diverse challenges with the potential to negatively affect successful teaching and learning. This requires appropriate interventions to improve school performance in spite of the rural-based challenges. The purpose of this study was to explain the measures whose implementation can yield improved learner performance and general quality of education at rural schools, with the aim of sustaining good rural school performance in standardised examinations.Case study design was used, which sampled teachers and education officials. Data was collected by means of a literature study, individual and focus group interviews. The data was analysed thematically. The findings revealed that education at rural schools can be improved by ensuring a conducive working environment, that is fully and well-resourced with all the teaching and learning essentials. The financial incentive that was being given to teachers need an increment, to be realistic and outweigh the challenges teachers were facing, alongside justifiable categorisation of schools according to which payment amount were made. In addition, rural schools need sufficient budget allocation to contain their operational and development expenses. An increase in budgetary allocation will also make resources available for vocational education curriculum as not all learners are academically gifted. Moreover, rural schools should capitalise on the advantages of school cluster system and share resources for improved school performance. Successful consideration and implementation of these measures are recommended as being helpful to rural schools in pursuit of good academic performance, in a sustainable fashion.
Phytochemistry and therapeutic effects of Alhagi spp. and tarangabin in the Traditional and modern medicine: a review

Alhagi maurorum is one of the species of Alhagi genus producing manna of Tarangabin. Tarangabin is mainly prepared in Iran and Afghanistan. The medicinal properties of Tarangabin and A. maurorum have been mentioned in some major Materia Medica manuscripts in the Islamic era. Tarangabin has various pharmacological properties including antioxidant, anti-inflammatory, antipyretic, diaphoretic, diuretic, expectorant, analgesic and gastrointestinal effects. The purpose of this review is to introduce Alhagi plant and its different species, to present its geographical distribution, and to review its phytochemical and pharmacological properties as well as traditional and folklore applications. Phytochemistry of different parts of Alhagi, such as root, leaf and manna is also explained in details. In addition, temperament and medicinal uses of Tarangabin mentioned in the Islamic traditional medicine (ITM) books are presented. Indeed, sparse clinical research has been done on the medicinal properties of Tarangabin, which calls for future well-designed trials.