Miracle-dz/UniFAR-FTUs huggingface dataset:
Efficient storage, retrieval and analysis of poker hands: An adaptive data framework

Abstract In online gambling, poker hands are one of the most popular and fundamental units of the game state and can be considered objects comprising all the events that pertain to the single hand played. In a situation where tens of millions of poker hands are produced daily and need to be stored and analysed quickly, the use of relational databases no longer provides high scalability and performance stability. The purpose of this paper is to present an efficient way of storing and retrieving poker hands in a big data environment. We propose a new, read-optimised storage model that offers significant data access improvements over traditional database systems as well as the existing Hadoop file formats such as ORC, RCFile or SequenceFile. Through index-oriented partition elimination, our file format allows reducing the number of file splits that needs to be accessed, and improves query response time up to three orders of magnitude in comparison with other approaches. In addition, our file format supports a range of new indexing structures to facilitate fast row retrieval at a split level. Both index types operate independently of the Hive execution context and allow other big data computational frameworks such as MapReduce or Spark to benefit from the optimized data access path to the hand information. Moreover, we present a detailed analysis of our storage model and its supporting index structures, and how they are organised in the overall data framework. We also describe in detail how predicate based expression trees are used to build effective file-level execution plans. Our experimental tests conducted on a production cluster, holding nearly 40 billion hands which span over 4000 partitions, show that multi-way partition pruning outperforms other existing file formats, resulting in faster query execution times and better cluster utilisation.
Assignment of the phosphoinositide-3-kinase, class 3 (PIK3C3) gene to porcine chromosome 6q22→q23 by somatic cell and radiation hybrid panel mapping

a Division of Applied Life Science, Gyeongsang National University, Jinju; b Korea Research Institute of Bioscience and Biotechnology, Daejeon; c National Livestock Research Institute, Rural Development Administration, Suwon; d Division of Animal Science and Resources, Chungnam National University, Daejeon; e National Institute of Subtropical Agriculture, Rural Development Administration, Cheju (Korea)
Early Extubation Protocol Following Valve and Coronary Artery Bypass Surgery

Background: Early extubation protocols can be safely implemented in most patients undergoing coronary artery bypass surgery. We have found that these results can be replicated in patients undergoing valve surgery and combined coronary bypass and valve surgery as well. Methods: We implemented an early extubation protocol on Apr 4th, 2011. Our goal was to extubate all appropriately selected patients within 6 h after arrival to our ICU. We utilized the Society of Thoracic Surgeons Adult Cardiac Surgical Database at our institution and compared our extubation times from Jan 1st, 2008–Apr 3rd, 2011 to Apr 4th, 2011-Dec 31st, 2014. We used a chi square test to compare how many patients were extubated within 6h, before and after implementation of this quality improvement project. Fisher’s exact tests were used as well when sample sizes were small. Results: Nearly seventy percent, 1295 of 1855 patients having cardiac surgery at Lahey Hospital and Medical Center were extubated within 6h after implementing our rapid wean protocol. This was a significant improvement compared to 29%, 455 of 1570 patients prior to our quality improvement project (p<0.0001). These results were seen for coronary artery bypass as well as valve procedures including combined aortic valve replacement and coronary bypass procedures. Conclusion: An early extubation protocol can be safely implemented in patients undergoing valve and combined valve and coronary artery bypass operations with similar success rates to those having coronary artery bypass surgery alone.
Effectiveness of Radial Extracorporeal Shock Wave Therapy (rESWT) When Combined With Supervised Exercises in Patients With Subacromial Shoulder Pain: A Double-Masked, Randomized, Sham-Controlled Trial

Background: Subacromial shoulder pain is a common complaint, and radial extracorporeal shock wave therapy (rESWT) is increasingly used to treat this condition. Although many therapists use rESWT in combination with supervised exercises, no studies have evaluated the additional effect of rESWT with supervised exercises for subacromial shoulder pain. Purpose: To assess whether rESWT is more effective than sham rESWT when combined with supervised exercises for improving pain and function in patients with subacromial shoulder pain. Study Design: Randomized controlled trial; Level of evidence, 1. Methods: Patients between 25 and 70 years of age with subacromial shoulder pain with and without calcification in the rotator cuff lasting at least 3 months were assessed for eligibility; 143 patients were recruited. Participants were allocated (1:1) by computer-generated randomization in blocks of 20 to receive either rESWT or sham rESWT in addition to supervised exercises. The rESWT and sham rESWT were performed once a week with additional supervised exercises once a week for the first 4 weeks. The following 8 weeks, the patients received supervised exercises twice a week. The primary outcome was change in the Shoulder Pain and Disability Index (SPADI) after 24 weeks. Patients and outcome assessors were masked to group assignment. Results: At 24 weeks, participants in both the sham group and the rESWT group had improved (P < .001) in SPADI score compared with baseline (−23.9 points [SD, 23.8 points] and −23.3 points [SD, 25.0 points], respectively), but there were no differences between the groups (mean difference 0.7; 95% CI, −6.9 to 8.3; P = .76). Prespecified subgroup analysis of patients with calcification in rotator cuff showed that the rESWT group had a greater improvement in SPADI score after 24 weeks (mean difference −12.8; 95% CI, −24.8 to −0.8; P = .018). Conclusion: Radial ESWT offered no additional benefit to supervised exercises in the treatment of subacromial shoulder pain after 24 weeks, except in the subgroup of patients with calcification in the rotator cuff. Registration: NCT01441830 (ClinicalTrials.gov identifier).
Endothelial Cell–Specific Overexpression of Del-1 Drives Expansion of Haematopoietic Progenitor Cells in the Bone Marrow

Hematopoietic stem cells (HSCs) are responsible for the maintenance of hematopoiesis under normal conditions and its adaptation to hematopoietic stress (1). HSCs are localised in the bone marrow (BM) in a micro-anatomic space designated as the HSC niche (2) comprising different cellular components. While osteoblasts predominantly contribute to the restoration of hematopoiesis after transplantation, endothelial and perivascular stromal cells form a perivascular niche, which promotes the self-renewal of HSCs and their multi-lineage differentiation, and, hence the maintenance of hematopoiesis (2). Cells of the perivascular niche not only provide the mechanical barrier between the BM microenvironment and circulation, but also regulate hematopoiesis, either through adhesive interactions with HSCs (3) or by the release of paracrine factors (4,5). The adhesive interactions of HSCs with endothelial and perivascular cells mediate both the trafficking of HSCs into and out of the BM (6) and their maintenance and proliferation potential (3). Developmental endothelial locus-1 (Del-1) is a secreted glycoprotein that interacts with integrins We have recently shown that Del-1 is expressed by important cellular components (endothelial, mesenchymal stromal and cells of the osteoblastic of the HSC niche, where it regulates hematopoietic progenitor function and their myeloid differentiation (10). This ability of Del-1 to act as a HSC niche factor was attributed to its interaction with β 3 integrin on hematopoietic progenitors (10). Here, we set out to precisely define the role of Del-1 as an endothelial cell-derived perivascular niche factor. To this end, we studied steady-state and regeneration hematopoiesis using an independent in vivo approach, namely mice with endothelial-specific overexpression of Del-1. We engaged transgenic mice with endothelial cell-specific overexpression of Del-1 (EC-Del1), generated by utilizing a tie2 promoter/enhancer construct (11,12). EC-Del1 mice
An Anomaly Detection Method Based on Multi-models to Detect Web Attacks

As Web attacks are constantly emerging and have caused enormous loss, the effective methods to protect the Web security are becoming increasingly required. We propose an anomaly detection method based on multi-models to detect Web attacks. The method is designed by inspecting the HTTP request messages to identify attacks. Three machine learning models, namely the probability distribution model, the hidden Markov model, and the one-class SVM model are employed to inspect different fields of the HTTP request messages to detect anomalies. The three models work together and the overall detection result is anomalous if at least one model reports an anomaly. The detection mechanism of each model and the corresponding feature extraction algorithm are presented. The experimental results show that the multi-model based detection method has apparent advantage on detecting Web attacks. It craftily makes each individual model to inspect the HTTP request fields that they excel at, thus achieving a high detection rate while keeping a low false alarm rate.
Aerial cooperative transporting and assembling control using multiple quadrotor–manipulator systems

ABSTRACT In this paper, a fully distributed control scheme for aerial cooperative transporting and assembling is proposed using multiple quadrotor–manipulator systems with each quadrotor equipped with a robotic manipulator. First, the kinematic and dynamic models of a quadrotor with multi-Degree of Freedom (DOF) robotic manipulator are established together using Euler–Lagrange equations. Based on the aggregated dynamic model, the control scheme consisting of position controller, attitude controller and manipulator controller is presented. Regarding cooperative transporting and assembling, multiple quadrotor–manipulator systems should be able to form a desired formation without collision among quadrotors from any initial position. The desired formation is achieved by the distributed position controller and attitude controller, while the collision avoidance is guaranteed by an artificial potential function method. Then, the transporting and assembling tasks request the manipulators to reach the desired angles cooperatively, which is achieved by the distributed manipulator controller. The overall stability of the closed-loop system is proven by a Lyapunov method and Matrosov's theorem. In the end, the proposed control scheme is simplified for the real application and then validated by two formation flying missions of four quadrotors with 2-DOF manipulators.
Discourses on the Toxic Effects of Internal Chemical Contamination in Catalonia, Spain

ABSTRACT Human exposure to and contamination by environmental toxic compounds generates discourses and practices that merit greater attention. In this article, we assess internal chemical contamination and the risk of toxic effects as an experience related to the production of meaning in everyday life. Drawing on the analysis of semantic networks of narratives from semi-structured interviews conducted with 43 informants in Catalonia, Spain, we consider participants’ perceptions of the health risks of toxic compounds, including social discourses on exposure, toxicity, and internal chemical contamination, and on responsibilities, consequences, and proposed strategies for controlling toxic compounds. Informants’ narratives on the relationships between nature and nurture suggest that they no longer perceive rigid boundaries separating the human body from the external environment and its chemical pollutants.
Sensor array for the detection of organic and inorganic contaminants in post-consumer recycled plastics for food contact

ABSTRACT Post-consumer recycled (PCR) plastic material is made by collecting used plastic products (e.g., bottles and other plastic packaging materials) and reprocessing them into solid-state pellets or flakes. Plastic recycling has positive environmental benefits, but may also carry potential drawbacks due to unwanted organic and inorganic contaminants. These contaminants can migrate into food packaging made from these recycled plastic materials. The purpose of this research was to identify economically viable real-time monitoring technologies that can be used during the conversion of virgin and recycled resin feedstocks (i.e., various blends of virgin pellets and recycled solid-state pellet or mechanically ground flake) to final articles to ensure the safety, quality and sustainability of packaging feedstocks. Baseline analysis (validation) of real-time technologies was conducted using industry-standard practices for polymer analysis. The data yielded supervised predictive models developed by training sessions completed in a controlled laboratory setting. This technology can be employed to evaluate compliance and aid converters in commodity sourcing of resin without exceeding regulatory thresholds. Furthermore, this technology allowed for real-time decision and diversion strategies during the conversion of resin and flake to final articles or products to minimise the negative impact on human health and environmental exposure. Graphical Abstract
Accounting for Non-Gaussian Sources of Spatial Correlation in Parametric Functional Magnetic Resonance Imaging Paradigms I: Revisiting Cluster-Based Inferences

In a recent study, Eklund et al. employed resting-state functional magnetic resonance imaging data as a surrogate for null functional magnetic resonance imaging (fMRI) datasets and posited that cluster-wise family-wise error (FWE) rate-corrected inferences made by using parametric statistical methods in fMRI studies over the past two decades may have been invalid, particularly for cluster defining thresholds less stringent than p < 0.001; this was principally because the spatial autocorrelation functions (sACF) of fMRI data had been modeled incorrectly to follow a Gaussian form, whereas empirical data suggested otherwise. Here, we show that accounting for non-Gaussian signal components such as those arising from resting-state neural activity as well as physiological responses and motion artifacts in the null fMRI datasets yields first- and second-level general linear model analysis residuals with nearly uniform and Gaussian sACF. Further comparison with nonparametric permutation tests indicates that cluster-based FWE corrected inferences made with Gaussian spatial noise approximations are valid.
Double sampling |S| control chart with variable sample size and variable sampling interval

ABSTRACT This study presents a control chart for monitoring shifts in the covariance matrix of a multivariate normally distributed process. This chart combines the double sampling, variable sample size and variable sampling interval features, and is called the DSVSSI |S| chart. A Markov chain approach is developed to design the DSVSSI |S| chart, by minimizing the average time to signal (ATS), for a specified shift size in the covariance matrix. The DSVSSI |S| chart has a better ATS performance compared to other existing charts. An example is given to illustrate the operation of the DSVSSI |S| chart.
Influence of Natural Exposure to Pollens and Domestic Animals on Airway Responsiveness and Inflammation in Sensitized Non-Asthmatic Subjects

Background: Atopy may be a risk factor in the development of asthma. Indoor allergens are considered to be more potent asthma inducers than outdoor ones such as pollens. Lower airway inflammation may be present in non-asthmatic subjects during natural exposure to relevant allergens and may eventually lead to the development of asthma. Aims: To document seasonal variation in lower airway responsiveness and inflammation in sensitized non-asthmatic subjects, during natural exposure to allergens, and to determine whether it is more marked in those exposed to animals to which they are sensitized. Methods: Twenty-two atopic subjects were seen during and out of the pollen season. All (but the controls) were sensitized to domestic animals, and to trees, grasses or ragweed. Eleven were not exposed to animals at home and 8 were exposed. They were compared with 3 normal controls. A respiratory questionnaire was administered, allergy skin prick tests, spirometry, methacholine challenge, blood and induced sputum with differential cell counts were obtained during the pollen season for all subjects. These tests were repeated out of the pollen season. Results: Throughout the study, none of the subjects had asthma symptoms. Mean PC20 was significantly lower in subjects exposed to animals compared with unexposed subjects or controls, both during and out of the pollen season. In season, subjects exposed to animals had significantly higher sputum eosinophil numbers than unexposed or normal control subjects. Conclusions: Non-asthmatic atopic subjects show variable degrees of airway responsiveness and inflammation. However, subjects exposed to animals show higher airway eosinophilia, which may suggest they are at increased risk of developing airway hyperresponsiveness and asthma.
Experimental analysis of impact of term weighting schemes on cluster quality

Term weighting schemes are used to identify the importance of each term with respect to a collection and assign weights to them accordingly. Document clustering uses these term weights to compare the similarity between documents. Several term weighting schemes are in use today, but none of them are specific to the clustering algorithms. The term frequency-based clustering techniques consider the documents as a bag of words while ignoring the relationship between the words. So, in this paper we focus our analysis on different term weighting schemes such as term frequency (tf), term frequency-inverse document frequency (tfidf), automatic text categorisation (ATC) without normalisation and ATC-inverse document frequency (ATCidf). In this paper, we have used the clustering tool CLUTO to experimentally study the impact of term weighting schemes on the quality of the clustering solution obtained by applying the Repeated Bisection Partitional Algorithm.
Complete mitochondrial genome of Plodia interpunctella (Lepidoptera: Pyralidae)

Abstract The complete mitochondrial genome sequence of Plodia Interpunctella (Lepidoptera: Pyralidae) was determined. The circular genome has a size of 15 733 base pairs, containing 36 gene protein-coding genes, two rRNA genes, and 21 tRNA genes. The overall base composition was 41.37% of A, 37.99% of T, 12.54% of G, and 8.10% of C. Furthermore, a phylogenetic tree was constructed based on complete mitogenomes of Plodia interpunctella and 11 closely related Pyralidae species to validate the taxonomy relationship. The complete mitochondrial genome of the P. interpunctella would provide more information for the evolution of Pyralidae family.
Temperamental Effortful Control Modulates Gender Differences in Late Positive Potentials Evoked by Affective Pictures in Adolescents

ABSTRACT We investigated whether effort control (EC) modulates gender differences in late positive potential (LPP) evoked by affective pictures. We collected EEG data from 46 healthy adolescents while they viewed 90 affective pictures. Relative to neutral pictures, boys showed larger LPP amplitudes for positive pictures compared to girls while girls showed larger LPP amplitudes for negative pictures compared to boys. Temperamental EC in boys negatively predicted LPP amplitudes for positive pictures, whereas EC in girls negatively predicted LPP amplitudes for negative pictures. These observations increase our understanding of the relationship between EC and gender difference in electrocortical maturation.
Immediate Postablation 18F-FDG Injection and Corresponding SUV Are Surrogate Biomarkers of Local Tumor Progression After Thermal Ablation of Colorectal Carcinoma Liver Metastases

The aim of this study was to determine whether intraprocedural 18F-FDG PET/CT can be used as a predictor of local tumor progression after percutaneous ablation of colorectal liver metastases. Methods: In this institutional review board–approved prospective study, 39 patients (19 men and 20 women; median age, 56 y) underwent split-dose 18F-FDG PET/CT-guided ablation followed by immediate biopsy and contrast-enhanced CT imaging of the ablation zone. Binary categorization of biopsy tissues was performed on the basis of the presence of only nonviable coagulation necrosis or viable tumor cells. Minimum ablation margin measurements from contrast-enhanced CT imaging were categorized as 0 mm, 1–4 mm, 5–9 mm, or greater than or equal to 10 mm. SUVs were obtained from PET/CT imaging, and SUV ratios were calculated from 3-dimensional regions of interest located in the ablation zone and surrounding normal liver. All predictive variables (biopsy, minimum margin distance, and SUV ratio) were evaluated as predictors of time to local tumor progression identified on imaging using competing-risks regression models (uni- and multivariate analyses). Results: A total of 62 consecutive ablations were evaluated. The mean SUV ratio was significantly higher for viable tumor–positive immediate postablation biopsies (n = 10) than for tumor-negative biopsies (n = 52) (85.8 ± 92.2 vs. 42.3 ± 45.5) (P = 0.03) and for a minimum margin size of less than 5 mm (n = 15) than for a minimum margin size of greater than or equal to 5 mm (n = 47) (78.5 ± 99.1 vs. 38.3 ± 78.5) (P = 0.01). After a median follow-up period of 22.5 (range, 7–52) months, 23 of 62 ablated tumors showed local tumor progression (37.1%). The local tumor progression rate was significantly higher for viable tumor–positive biopsies (8/10) than for negative biopsies (15/52) (80% vs. 29%) (P = 0.001) and for a minimum margin size of less than 5 mm (9/15) than for a minimum margin size of greater than or equal to 10 mm (2/15) (60% vs. 13%) (P = 0.02) but not 5–9 mm (37.5%; 12/32) (P = 0.5). In a competing-risks analysis, biopsy results (P = 0.07) and the minimum margin size (P = 0.08) were borderline significant, but the SUV ratio was not (P = 0.22). However, for negative biopsy ablations, the minimum margin size and SUV ratio were predictive imaging factors for local tumor progression; subdistribution hazard ratios were 0.564 (0.325–0.978) (P = 0.04) and 1.005 (1.001–1.009) (P = 0.005), respectively. Conclusion: The SUV ratio and minimum margin size can independently predict colorectal metastasis local tumor progression after liver ablation when there are no viable tumor cells on immediate postablation biopsies.