Miracle-dz/UniFAR-FTUs huggingface dataset:
Evidence of Exercise-Induced Arterial Hypoxemia in Prepubescent Trained Children

Exercise-induced arterial hypoxemia (EIAH) is a recognized phenomenon in highly trained adults. Like adult athletes, prepubescent trained children may develop high-level metabolic demand but with a limited lung capacity in comparison with adults. The purpose of this investigation was to search for evidence of EIAH in prepubescent trained children. Twenty-four prepubescent (age: 10.3 ± 0.2 y) trained children (10.0 ± 0.7 h of weekly physical activity) performed pulmonary function tests and a graded maximal exercise test on a cycle ergometer. EIAH was defined as a drop of at least 4% from resting level arterial oxygen saturation (Sao2) measured by pulse oximetry. EIAH was observed in seven children. Forced vital capacity (FVC), ventilatory response to exercise (ΔV˙E/ΔV˙co2), and breathing reserve at maximal exercise were significantly lower, whereas tidal volume relative to FVC was higher in hypoxemic children than in nonhypoxemic children; weekly physical activity and maximal oxygen uptake were similar. Moreover, positive relationships were found between Sao2 at maximal exercise and breathing reserve (r = 0.56; p < 0.05) or volume relative to FVC (r = 0.70; p < 0.01). EIAH may occur in prepubescent trained children with a relatively low maximal oxygen uptake (42 mL · min−1 · kg−1); however, the mechanisms remain unclear and need to be investigated more accurately.
Transfemoral aortic valve replacement with the repositionable Lotus Valve System in high surgical risk patients: the REPRISE I study.

AIMS To assess outcomes with a new fully repositionable and retrievable valve for transcatheter aortic valve replacement (TAVR). METHODS AND RESULTS The Lotus Aortic Valve System is designed to facilitate precise positioning and minimise paravalvular regurgitation. REPRISE I enrolled symptomatic, high-surgical-risk patients with severe aortic stenosis. The primary endpoint (clinical procedural success) included successful implantation without major adverse cardiovascular or cerebrovascular events (MACCE). In all patients (N=11) the first Lotus Valve was successfully deployed. Partial resheathing to facilitate accurate placement was attempted and successfully performed in four patients; none required full retrieval. The primary endpoint was achieved in 9/11 with no in-hospital MACCE in 10/11. There was one major stroke; in another patient, discharge mean aortic gradient was 22 mmHg (above the primary endpoint threshold of 20 mmHg), but improved to 15 mmHg at 30 days. The cohort's mean aortic gradient decreased from 53.9±20.9 mmHg at baseline to 15.4±4.6 mmHg (p<0.001) at one year; valve area increased from 0.7±0.2 cm2 to 1.5±0.2 cm2 (p<0.001). Discharge paravalvular aortic regurgitation, adjudicated by an independent core laboratory, was mild (n=2), trivial (n=1), or absent (n=8). Four patients required a permanent pacemaker post-procedure. There were no deaths, myocardial infarctions or new strokes through one year. CONCLUSIONS Initial results support proof-of-concept with the Lotus Valve for TAVR.
A self-* auction server: design principles, architecture and implementation

The use of economic models to handle resource allocation in the grid is a reality. Auction mechanisms are used in grid and distributed testbeds to elicitate user's preferences while improving the performance of the system. Existing implementations rely on single auction mechanisms to allocate resources whilst grids are heterogeneous in nature. Many different applications cohabitate having different workflow requirements such as bag of tasks executions or real time interaction that cannot be dealt efficiently by a single mechanism. In that scenario it would be more realistic to allocate resources using the most suitable mechanism for each situation, enabling also its configuration, deployment and management at runtime. Therefore, the paper presents the design principles, architecture and implementation of a configurable auction server (CAS). The auction server offers support for the deployment, configuration and execution of different auction mechanisms, facilitating the task of market mechanism developers and enabling the execution of distributed marketplaces according to local demand.
Path Computation Element (PCE) Communication Protocol (PCEP)

This document specifies the Path Computation Element (PCE) Communication Protocol (PCEP) for communications between a Path Computation Client (PCC) and a PCE, or between two PCEs. Such interactions include path computation requests and path computation replies as well as notifications of specific states related to the use of a PCE in the context of Multiprotocol Label Switching (MPLS) and Generalized MPLS (GMPLS) Traffic Engineering. PCEP is designed to be flexible and extensible so as to easily allow for the addition of further messages and objects, should further requirements be expressed in the future. [STANDARDS-TRACK]
High yield sub-0.1µm2 6T-SRAM cells, featuring high-k/metal-gate finfet devices, double gate patterning, a novel fin etch strategy, full-field EUV lithography and optimized junction design & layout

We report high yield sub-0. 1µm2 SRAM cells using high-k/metal gate finfet devices. Key features are (1) novel fin patterning strategy, (2) double gate patterning (3) new SRAM cell layout and (4) EUV lithography and robust etch/fill/CMP for contact/metal1. 0. 099µm2 finfet 6T-SRAM cells show good yield. And smaller cells (0.089µm2) are functional. Further yield improvement is possible by junction optimization using extension less junction approach and further cell layout optimization.
An Actor-Partner Interdependence Model on Family Resilience and Subjective Wellbeing

In times of crisis the family often react together as a unit of response, as though a combat unit. The concept of family resilience has been identified as a coping resource for the family unit even if the crisis affected only one individual of the family. Family resilience works in concert with individual psychological resilience to protect the individual from excess negative impact and to improve positive outcomes such as subjective wellbeing. However, the impact of family resilience on the adaptive outcome is far more complex than individual resilience. The present study aims to identify the internal dynamics between the individual actor and her familial partner, using the Actor-Partner Interdependence Model. A total of 38 family dyads, each pair consisted of a hospital nurse and one of her family members participated in the present study. Among them are 49 females and 27 males, with mean age of 40.62 years old. The nurses were recruited from two major public hospitals that admitted patients and patients suspected of being infected with an infectious disease during a pandemic out-break. The family members were 2 parents, 24 spouse, 6 siblings, and 6 children of the nurses. Main effects of actor’s resilience and partner’s resilience, as well as interaction effect between actor’s and partner’s resilience, on actor’s subjective wellbeing, were found. This suggests interdependence effects of individual’s resilience and the other party’s wellbeing. Results indicated that the 1) the multifaceted-multi-processed family resilience affects the individual outcomes in different ways: Family resilience of familial process and function showed only actor effect on individual subjective wellbeing, family resilience of shared beliefs and emotional regulation however showed actor and partner effects and with the partner showed higher effect. 2) The hypothesis on interdependence effects was supported for the family resilience dimensions of meaning-making and emotional regulation.
QUALITATIVE ASSESSMENT OF BREAST RECONSTRUCTION IN A SPECIALIST BREAST UNIT

Background: Breast reconstruction is an integral part of the surgical management of women with breast cancer. It is often performed by plastic surgeons but, in some centres, it is performed by breast surgeons trained in breast reconstruction and oncoplastic surgery. We evaluated the objective and subjective outcomes of reconstruction for breast cancer at the Royal Adelaide Hospital Breast Unit (Adelaide, Australia) between 1990 and June 2002.
A Multivariate Dynamic Systems Model for Psychotherapy With More Than One Client

The dynamics of the give and take between therapist and client(s) is frequently of interest to therapy process researchers. Characterizing the ways that therapists respond to clients and clients respond to therapists can be challenging in therapeutic encounters involving a single therapist and a single client. The complexity of this challenge increases as the number of people involved in a therapeutic encounter increases not only because there are more people responding to one another but also because the patterns of responding can become more complex. This manuscript demonstrates how dyadic cross-lagged panel models can be extended to psychotherapeutic encounters involving 3 people and used to test processes that exist between dyadic subsets of the larger group as well as the group as one cohesive unit. Three hundred seventy-nine talk turns of fundamental frequency from a couple therapy session were modeled using 3 dyadic cross-lagged panel models, and each individual’s respiratory sinus arrhythmia (RSA) was treated as a moderator. Although the regression coefficients for each dyadic subset (e.g., therapist–husband) were nonsignificant, an eigenvalue/eigenvector decomposition of the regression coefficients from the 3 dyadic cross-lagged panel models suggests that interdependence exists at the level of the whole group (i.e., therapist–husband–wife) rather than between pairs of individuals within the group (e.g., husband–wife). Further, an interaction involving husband’s RSA suggested that interdependence involving the husband ceased when the husband displayed greater regulatory effort. This combination of statistical methods allows for clearly distinguishing between dyadic therapeutic processes and group-level therapeutic processes.
Dispersion and controllability for the Schrödinger equation on negatively curved manifolds

We study the time-dependent Schr\"odinger equation $ \imath\frac{\partial u}{\partial t}=-1/2\Delta u,$ on a compact riemannian manifold on which the geodesic flow has the Anosov property. Using the notion of semiclassical measures, we prove various results related to the dispersive properties of the Schr\"odinger propagator, and to controllability.
Entrepreneurial Perceptions and E-business Opportunity Discovery: Evidence from China

In the era of e-business, firms are changing existing business models and/or create new business models through the discovery of e-business opportunities. However, how entrepreneurial perceptions can be activated to discover e-business opportunities is still underexplored. This study proposed a research model that integrated the subjectivist theory of entrepreneurship (STE), the resource-based view and the institutional theory to explain how external pressures and IT infrastructure maturity influence entrepreneurial perceptions, which further promote the discovery of e-business opportunities. Data collected from 203 traditional firms in China was used to examine the research model. The result supported that the causal relationships from external pressures and IT infrastructure maturity to ebusiness opportunity discovery are partially mediated by entrepreneurial perceptions. In addition, external pressures and IT infrastructure maturity pose different effects on three types of entrepreneurial perceptions. Practitioners looking for innovative use of e-business should view external pressures as an external driving force and IT infrastructure as an internal driving force for motivating entrepreneurial perceptions.
An Adaptive MAC Protocol Based on Path-Diversity Routing in Ad hoc Networks

We present the design and simulation of an adaptive MAC protocol based on the path-diversity routing information for ad hoc networks. As a routing protocol, a multipath routing protocol based on SPAFAR is used, where a route discovery algorithm finds multiple paths significantly reduce the delay in finding an alternate path. The information about multiple paths discovered in the network layer is exploited by the MAC layer in order to forward a frame over the best hop out of multiple hop choices. The performance of our approach is compared with IEEE 802.11 MAC through the simulation. The results show that our scheme exhibits a significantly better performance rather than the IEEE 802.11 MAC protocol in terms of packet overhead and end-to-end throughput.
Modeling of a Lithium-Ion Capacitor and Its Charging and Discharging Circuit in a Model-Based Design

For several years now, electric vehicles (EVs) have been expected to become widely available in the micro-mobility field. However, the insufficiency of such vehicles’ battery-charging and discharging performance has limited their practical use. A hybrid energy storage system, which comprises a capacitor and battery, is a promising solution to this problem; however, to apply model-based designs, which are indispensable to embedded systems, such as the electronic control units used in EVs, a simple and accurate capacitor model is required. Within this framework, a lithium-ion capacitor (LIC) model is proposed, and its charging and discharging performances are evaluated against an actual LIC. The model corresponds accurately to the actual LIC, and the results indicate that the proposed LIC model will work well when used with Model-Based Design (MBD).
Jawsfest: new perspectives on neural crest lineages and morphogenesis

The neural crest is a fascinating population of cells that migrate long distances in the developing embryo to generate many different derivatives. It also occupies a central position in the origin and patterning of the vertebrate head, and has generated debates about issues such as cell programming versus plasticity and the role of cell death in early morphogenesis. These aspects of the field were revisited and discussed in a recent meeting organized to honour the retirement of Jim Weston and his contribution to the field
Two-Color niBin Type II Superlattice Infrared Photodetector With External Quantum Efficiency Larger Than 100%

We report on a two-color <italic>niBin</italic> type II InAs/GaSb superlattice (SL) infrared photodetector. The two-color detection is realized by changing the applied bias polarity. At room temperature (RT), the 50% cutoff wavelength is <inline-formula> <tex-math notation="LaTeX">$3.62~\mu \text{m}$ </tex-math></inline-formula> for one band and is <inline-formula> <tex-math notation="LaTeX">$4.91~\mu \text{m}$ </tex-math></inline-formula> for the other at different bias voltage. The measured quantum efficiency (QE) of one band at the peak response is 114% at RT. This unusual QE is attributed to the large gain due to the photoconductive working mechanism. When temperature is raised from 90 to 300 K, the conduction of the SL absorber changes from <inline-formula> <tex-math notation="LaTeX">${p}$ </tex-math></inline-formula> to <inline-formula> <tex-math notation="LaTeX">${n}$ </tex-math></inline-formula> and thus the detector changes from photovoltaic to photoconductive when a bias voltage is applied.
Language and cognition—joint acquisition, dual hierarchy, and emotional prosody

concepts. J. Cogn. Neurosci. 17, 1–13. doi: 10.1162/0898929054021102 Brighton, H. , Smith, K. , and Kirby, S. (2005). Language as an evolutionary system. Phys. Life Rev. 2, 177–226. doi: 10.1016/j.plrev. 2005.06. 001 Cangelosi, A. , and Parisi, D. (eds.). (2002). Simulating the Evolution of Language. London: Springer. doi: 10.1007/978-1-4471-0663-0 Chomsky, N. (1995). The Minimalist Program. Cambridge: MIT Press. Christiansen, M. H. , and Kirby, S. (2003). Language Evolution. New York, NY: Oxford University Press. doi: 10.1093/acprof:oso/9780199244843.001. 0001 Croft, W. , and Cruse, D. A. (2004). Cognitive Linguistics. Cambridge: Cambridge University Press. doi: 10.1017/CBO9780511803864 Deacon, T. W. (1997). The Symbolic Species: The CoEvolution of Language and the Brain.NewYork, NY:
SENTIO: A Hardware Platform for Rapid Prototyping of Wireless Sensor Networks

A wireless sensor network is always an integrated part of a system. The physical and logical structure of the system, where the sensor network is integrated, are together with other environmental requirements the constraints for the design of the network and the wireless sensor devices. These requirements are very different for different applications and even for one specific system the requirements may be very different on the sensor devices. When developing efficient wireless sensor devices these constraints must be taken into consideration. The diverse constraints we are facing when developing wireless sensor networks and devices for various applications makes it necessary to have a platform-based development approach where as much of the components can be re-used. For the communication, the standard IEEE 802.15. 4 provides an excellent platform for developing short range power aware sensor networks. In this paper a hardware platform is presented with its modular structure it provides a highly flexible solution suitable for rapid prototyping of wireless sensors. This platform is a tool for developers of wireless sensor devices as well as system integrators that need to explore different system solutions experimentally
Effects of synergists on the metabolism and toxicity of anticholinesterases.

Insecticide synergists enhance insecticidal action through their ability to block the enzymatic detoxification of insecticides with which they are combined. The structure of the synergist is therefore determined by the nature of the insecticide and the critical biochemical pathway responsible for its degradation.Synergists can be broadly classified as either analogue synergists, whose structure closely resembles that of the insecticide they synergize, or inhibitors of microsomal oxidation. Metabolism of the phenyl methylcarbamates is effected largely by the microsomal enzymes. Consequently microsomal enzyme inhibitors, such as the methylenedioxyphenyl compounds, the aryloxyalkylamines, the thiocyanates, the propynyl aryl ethers, and the 1,2,3-benzothiadiazoles, are all effective carbamate synergists. The detoxification pathways of the organophosphates, however, are more complex and include hydrolysis, dealkylation, and carboxylesterase pathways as well as oxidation. Because phosphorothioates are activated by oxidation, their toxicity is often antagonized by oxidase inhibitors. The effectiveness of different synergists towards resistant strains of insects is likely to vary in a manner that reflects the critical metabolic pathway on which resistance depends.
Bioartificial Cartilage

Cartilage is a highly differentiated tissue. Its three-dimensional composition of cells and matrix is able to resist intensive mechanical loads. The capacity of cartilage tissue for regeneration is limited. Chondrocytes are responsible for matrix production of cartilage tissue. Enzymatic isolation and expansion of chondrocytes with cell culture techniques has been improved in the last years. These cells can be cultured on different three-dimensional culture systems suitable for transplantation to repair localized cartilage defects. Two types of bioresorbable polymer fleece matrices (PLLA and a composite fleece of polydioxanone and polyglactin) and lyophilized dura as a biological carrier are tested. Phenotypic and morphological appearance of the cultured articular rabbit chondrocytes is preserved on all three types of transport media. Production of glycosaminoglycans has been shown by Alcian blue staining, production of collagen by azan staining. Chondroitin 4- and 6-sulfate are detected immunohistochemically in the created constructs. The different carriers have specific characteristics regarding their suitability for the creation of bioartificial cartilage. This tissue is transplantable into articular cartilage defects and could, therefore, improve the minor intrinsic healing capacity of cartilage tissue.
Constructal optimization of an elemental proton exchange membrane fuel cell used in the electric vehicles

An important part of the electric vehicle is the electric power supply. Several types of sources are known, one of which is the Fuel Cell (FC). Its applications range from rockets to household applications. More recently it was suggested that interconnecting the car provided with FC with the home network or even with the power distribution system might solve their recharging problem. On the other hand, for cars parked over 90% of the time it might be desired to use the power produced by the FC for domestic or commercial purposes thus covering more than half of the initial investment in the purchase of the vehicle. Another advantage is the quite high efficiency of the FCs as compared to other practical conversion methods. Although, theoretically, the isothermal efficiency of reactions in the FC can reach 80%, practically it is about 50–60%, still significant. This paper presents several constructive solutions of an elemental Proton Exchange Membrane FC (PEMFC).
Governance Models and Outcomes to Foster Public Value Creation in Smart Cities

The growth of smart cities is forcing governments to focus their efforts on the increase of public value creation. Based on a literature review of prior research and on a questionnaire about the perception of city practitioners in European smart cities included in the EUROCITIES network, this paper seeks to analyze the public value creation under the context of the smart cities, examining the model of citizen participation, the responsibility of smart city development and the outcomes to be achieved in smart cities. Results indicate that public value creation surpass the capacities, capabilities, and reaches of their traditional institutions and their classical processes of governing, and therefore new and innovative forms of governance are needed to meet it. This way, the creation of public value under the context of the smart cities is based on smart urban collaboration, which promotes the use of new technologies to adopt a more participative model of governance.
Bradyrhizobium japonicum delta-aminolevulinic acid dehydratase is essential for symbiosis with soybean and contains a novel metal-binding domain

The Bradyrhizobium japonicum hemA gene product delta-aminolevulinic acid (ALA) synthase is not required for symbiosis of that bacterium with soybean. Hence, the essentiality of the subsequent heme synthesis enzyme, ALA dehydratase, was examined. The B. japonicum ALA dehydratase gene, termed hemB, was isolated and identified on the basis of its ability to confer hemin prototrophy and enzyme activity on an Escherichia coli hemB mutant, and it encoded a protein that was highly homologous to ALA dehydratases from diverse organisms. A novel metal-binding domain in the B. japonicum ALA dehydratase was identified that is a structural composite of the Mg(2+)-binding domain found in plant ALA dehydratases and the Zn(2+)-binding region of nonplant ALA dehydratases. Enzyme activity in dialyzed extracts of cells that overexpressed the hemB gene was reconstituted by the addition of Mg2+ but not by addition of Zn2+, indicating that the B. japonicum ALA dehydratase is similar to the plant enzymes with respect to its metal requirement. Unlike the B. japonicum hemA mutant, the hemB mutant strain KP32 elicited undeveloped nodules on soybean, indicated by the lack of nitrogen fixation activity and plant hemoglobin. We conclude that the hemB gene is required for nodule development and propose that B. japonicum ALA dehydratase is the first essential bacterial enzyme for B. japonicum heme synthesis in soybean root nodules. In addition, we postulate that ALA is the only heme intermediate that can be translocated from the plant to the endosymbiont to support bacterial heme synthesis in nodules.