Miracle-dz/UniFAR-FTUs huggingface dataset:
Metrical Flux: Towards Rhythm Generation in Continuous Time

This work-in-progress report describes our approach to expressive rhythm generation. So far, music generation systems have mostly focused on discrete time modelling. Since musical performance and perception un-folds in time, we see continuous time modelling as a more realistic approach. Here we present work towards a continuous time rhythm generation system. In our model, two neural networks are combined within one integrated system. A novel Adaptive Frequency Neural Network (AFNN) models the perception of changing periodicities in metrical structures by entraining and resonating nonlinearly with a rhythmic input. A Recurrent Neural Network models longer-term temporal relations based on the AFNN’s response and generates rhythmic events. We outline an experiment and evaluation method to validate the model and invite the MUME community’s feedback.
Does liquidity disclosure regulation negatively affect liquidity holdings in the banking system?

I study a spillover effect of mandatory bank liquidity disclosure on banks’ liquidity holdings, using the exogenous shock of the US Liquidity Coverage Ratio (LCR) disclosure requirement. I find that the disclosure reduced non-disclosing banks’ liquidity holdings, especially those that learned more from the disclosure. To pin down an information channel through which liquidity disclosure affected liquidity holdings, I show that the reduction in liquidity is unlikely caused by the requirement on minimum LCR levels, that the reduction is greater when the disclosure is more important for other banks, and that the disclosure reduced banks’ incentive to form relationships with the disclosing banks. Overall, my results suggest an unintended–and potentially undesirable–externality of liquidity disclosure regulation on the financial system. ∗I thank Philip Berger, Jonathan Bonham, Matthias Breuer, Hans Christensen, Douglas Diamond, John Gallemore, Pingyang Gao, João Granja, Zhiguo He, Anil Kashyap, Anya Kleymenova, Christian Leuz, Miao Liu, Jinzhi Lu, Valeri Nikolaev, Thomas Rauter, Haresh Sapra, Douglas Skinner, Andrew Sutherland, Joanna Wu, and workshop participants at Chicago Booth for helpful comments and suggestions. I also thank two anonymous bankers from Goldman Sachs for providing institutional insights. All errors are my own.
Systematics of hypsilophodontidae and basal Iguanodontia (dinosauria: Ornithopoda)

The phylogenetic relationships of species attributed to the ornithopod family Hypsilophodontidae are evaluated using morphological characters from the skull, dentition, and postcranium. Based on our analyses, Hypsilophodontidae constitutes a monophyletic taxon that comprises the sister taxon to Iguanodontia, together forming Euornithopoda. Three clades within the family are consistently demonstrated: Zephyrosaurus schaff+Orodromeus makelai, Parksosaurus warreni+Hypsilophodon foxii and Yandusaurus hongheensis+Othnielia rex. Thescelosaurus neglectus is the sister taxon to these six genera and constitutes the basal hypsilophodontid. Tenontosaurus tilletti is the basal member of Iguanodontia, with species of Dryosaurus and Camptosaurus as higher taxa within the clade. To understand the effects missing data may have on tree topology, tree length, and consistency indices, poorly represented characters were secondarily removed from the character matrix. In these analyses, all relationships remain stable, but tre.
ANXIOLYTIC PROFILE OF A POLYHERBAL DRUG MENTAT

Background: Mentat, a polyherbal psychotropic preparation, used for its memory enhancing property. Limited studies established its antianxiety property, so we evaluated antianxiety profile of mentat in animal models. Materials and Methods: Antianxiety activity of mentat was assessed in four groups of rats (n=6). The animals were treated orally (p.o.) with 300 and 600 mg/kg of mentat for seven days. On seventh day animals were subjected to Elevated Plus Maze (EPM) test, alprazolam (0.25 mg/kg), was a reference drug. Increase in time spent and number of entries in open arm was considered as an index of antianxiety activity. Results: Mentat exhibits dose dependent antianxiety activity in EPM. Mentat in dose of 300 mg/kg depicted significant antianxiety activity as compared to control group only (P<0.001), while at dose of 600 mg/kg showed antianxiety activity, which was significant as compared to control and reference drug (P<0.001) in EPM. Conclusion: Results of this study if substantiated by further experimental research suggests that mentat has antianxiety activity. Clinical trials document antianxiety profile of mentat but these trials had limitations like small sample size and single institutional setting. More research is required to develop novel plant products which are safe and have minimal adverse drug effect.
An MDA Approach For Multi-Platform Agent Design Patterns

—The object-oriented paradigm enriched with the definition of design patterns proved successful in lowering the development time and number of errors in produced software; now a similar phenomenon is occurring for multi-agent systems, where this is related to the great effort that has been currently spent in methodology definitions by several researchers. In this work we describe our experiences in the identification, description, production and application of agent patterns. Upon our pattern definition, we base a reuse process that can be considered as a crosscutting phase of the entire PASSI design methodology, from analysis to development. A classification criteria and a documentation template was defined in order to help user in selecting a pattern from the repository. The pattern solution is described using an MDA multi-level approach allowing us to automatically produce both source code (for multiple agent platforms) and UML diagrams (usually almost a structural and a dynamic diagram) useful for documenting the process. A concrete case study is reported in order to illustrate our pattern reuse approach, and some experimental results are reported for supporting the theory.
Preprocessing Texts in Issue Tracking Systems to improve IR Techniques for Trace Creation

Multiple studies showed the usefulness of requirements traceability in developing software and systems. Still, a major challenge is to establish the required trace links among development artifacts. Often, information retrieval (IR) techniques combined with text similarity measures are used for this task. Applying these ideas to requirements texts found in issue tracking systems (ITS) of open source systems is diﬃcult, because often these texts are structured and not only contain natural language. Thus, preprocessing of the textual information is required to extract the diﬀer-ent kinds of text. In this paper, the authors study the structure of issue descriptions found in open source systems and identify several categories of text found therein, such as source code and stack traces. These text categories allow a more precise application of similarity analysis in order to create traces by comparing textual information of the same kind, i. e. source code with source code and natural language with natural language.
Towards Linked Open Scientiﬁc Communication: Sharing, Analyzing, Exchanging

Many systems have emerged to help researchers seeking for relevant information about the research domain of their interest. Although with their support scientiﬁc documents are easily available by now, scientists need more and more advanced support while searching for diﬀerent kinds of bibliographical information. This includes ﬁnding most important research trends, major papers, auspicious approaches, established conference series as well as the search for the most active groups for a speciﬁc research topic, similar approaches, partner candidates active in a certain domain, related research schools, etc. Answering such queries is still a hard and time-consuming task for researchers. We believe that having a comprehensive system with recommender services based on Linked Open Data can help to support researchers in this respect. In this paper, we address the problem and present a rough overview of our approach over one particular use-case and possible analysis over citation graphs using enriched metadata of publications.
Water Quality Assessment using Environmetrics and Pollution Indices in a Tropical River, Kerala, SW Coast of India

Envirometrics and pollution indices are proxies to assess water quality of a wetland ecosystem. Hence, the present study is focused on establishing water quality and elucidating the pollution status of Karamana River (KR) in Kerala, SW coast of India. The Karamana River Basin – KRB (n=6th; L= 68 km, A=695 km2), is the main source of water for domestic and drinking purpose in Thiruvananthapuram city. The Killi River (n= 5th; L= 24 km, A= 102 km2), the largest tributary of KR, carry heavy load of pollutants mainly from city and joins KR towards its downstream side. For this study, about 12 sampling stations were selected along the KR from upstream to downstream (interval= ~3km), and water samples (n=12x2= 24) were collected during non-monsoon (NON) and monsoon (MON) of 2015 to assess the variability and sourcing of key hydrochemical variables. Environmetric methods, viz., Pearson Correlation and Principal Component Analysis (PCA) were applied for apportionment of pollution sources significantly responsible for the surface water quality. It was found that sewage effluents and seawater intrusion were the primary factors deteriorating water quality in downstream. Further, the results of water quality analyses and Pollution Indices, viz., Organic Pollution Index (OPI), Eutrophication Index (EI) and Comprehensive Pollution Index (CPI) indicate that lower reaches (L= ~4 km) of KR is seriously polluted. A distinct Zone of Pollution Influence (ZPI) has been delineated based on the indices and this attempt is first of its kind in KR. The present study provides several noteworthy contributions to the existing knowledge on the factors influencing surface water quality and serves as a baseline data for watershed managers and administrators. Current World Environment www.cwejournal. org ISSN: 0973-4929, Vol. 15, No. (1) 2020, Pg. 11-23
Dynamic Analysis of Soil Structure Interaction of Pile Supported Frame Structure

The Soil-pile-structure interaction is a complex phenomenon and which can affect the response of structure during dynamic excitation such as earthquake. To deal with such complexities, it is necessary to use numerical methods like Finite Elements for analyzing system behavior under dynamic excitation. In this paper, a five storied (G+4) two bay frame structures supported by pile group is considered for evaluation of structural response and soil structure interaction during transient event. The pile group is embedded in sandy soil mass. To simplify the full nonlinear transient dynamic problem, load time history is applied on edge of top structure beam in a lateral direction with triangular wave to predict structure response in one cycle. A Finite element method (FEM) based approach is used to model structure in ANSYS Mechanical using full transient method. The analysis load boundary conditions are derived from United States (US) Geological Survey for the creation of global shake map. This loads are typically observed high acceleration and damage levels during earth quake in past. The entire system is studied for five different peak loads with same frequency and structural responses are compared with and without soil effect under same dynamic load.
The response of Chamaecyparisnootkatensis stecklings to seven nutrient regimes

Yellow cypress (Chamaecyparisnootkatensis (D. Don) Spach) stecklings (rooted cuttings) of two clones from each of three provenances representing northern and southern Vancouver Island and the lower mainland, British Columbia, were grown in inert rooting medium and fertilized with seven nutrient solutions. The stecklings were compared for their growth and photosynthetic responses to (i) deficiencies of nitrogen, phosphorus, and potassium separately, or a deficiency of all three macronutrients; (ii) nutrients supplied in excess; and (iii) nutrients supplied at constant or exponentially increasing rates. One clone from the northern Vancouver Island provenance was consistently more productive than the others, having the greatest total dry weight and highest net photosynthetic rate in all nutrient treatments. The "complete" nutrient mix supplied in exponentially increasing volumes provided maximum response in growth and photosynthesis for all clones. This response was not significantly better than that of stec.
THE SOCIABLE WEAVER, PART 3: BREEDING BIOLOGY AND MOULT

Summary Maclean, G. L. 1973. The Sociable Weaver, Part 3: Breeding biology and moult. Ostrich 44: 219–240. Rain or some associated phenomenon is the principal Zeitgeber releasing breeding in the Sociable Weaver. The species does not breed in the absence of rain. The same nest chambers are used for breeding as are used for roosting throughout the year. The Sociable Weaver is monogamous. The clutch size varies from two to six eggs, larger clutches being more common after good rains than in relatively poorer breeding periods. Food supply may therefore be the proximate factor regulating clutch size. Replacement clutches are not necessarily smaller than first clutches. The mean clutch size within a breeding period decreases with an apparent decrease in food supply. The parents share parental duties about equally. Up to four successive broods may be raised in a single breeding period; a breeding period may last up to nine months and may occur at any time of the year according to the somewhat erratic rainfall wh.
MASOM: A Musical Agent Architecture based on Self-Organizing Maps, Affective Computing, and Variable Markov Models

Musical Agent based on Self-Organizing Maps (MASOM) is a machine improvisation software for live performance. MASOM plays experimental music and free improvisation. The agent perceives and generates audio signals. MASOM combines Self-Organizing Maps for sound memory, Variable Markov Models for musical structure, and Affective Computing for machine listening. The agent learns the sonic content and the musical structure to generate live performances. MASOM’s ofﬂine learning uses an audio corpus of recordings of performances or compositions. The machine listening module of MASOM extracts high-level features such as eventfulness, pleasantness, and timbre. The agent listens to itself and other performers to decide what to play next.
Chemical Composition and Bioactive Potential of Dehydrated Peels of Benincasa hispida, Luffa acutangula, and Sechium edule

Dehydrated peels from ash gourd (Benincasa hispida), ridge gourd (Luffa acutangula), and cho-chow marrow (Sechium edule) were analyzed for chemical composition and bioactive potential. The range of constituents per 100g dry peels were protein, 3 to 15 g; insoluble fiber, 45 to 58 g; ether extractives, 2.3 to 3.3 g; iron, 5.1 to 17.4 mg; calcium, 307 to 704 mg; tannins, 580 to 848 mg; carotenoids, 1,712 to 35,663 μg; and ascorbic acid, 37 to 51 mg. Polyphenols, total antioxidant activity, free radical scavenging activity (FRSA), and reducing power of peel were highest in aqueous extracts. FRSA of cho-chow marrow peel was the highest (87.32%) followed by ridge gourd (85.4%) and ash gourd (63.31%) peels that correlated well with bioactive components. Methanol and aqueous extracts of the peel exhibited bile acid binding (61%–98%) and α-amylase inhibitory activity.
PII: S0304-3940(02)00227-6

We report the oral picture naming performance of the German aphasic MW who presented with frequent meaning related word substitutions (e.g. tiger ) lion) and word finding blockings (omissions) while his phonological capacities at the single word level were nearly preserved. Targets were controlled for their ‘semantic competitiveness’, that is, whether there exist closely meaning related lexical competitors or not. Semantic errors were far more numerous with the highly competitive targets than with the low competitive ones. However, omissions were more frequent with the low competitive items so that the sum of the semantic errors and of the omissions was comparable in both conditions. This inverse and compensatory relationship suggests that both error types are not mutually independent. The found pattern is at odds with serial psycholinguistic theories which locate word selection (and misselection) and word form access (and blockings) at different and serially connected stages of word production but supports theories which allow for a parallel architecture in lexical activation and selection involving the word form level. q 2002 Elsevier Science Ireland Ltd. All rights reserved.
Differential Effects of REV-ERBa/b Agonism on Cardiac Gene Expression, Metabolism, and Contractile Function in a Mouse Model of Circadian Disruption.

Cell autonomous circadian clocks have emerged as temporal orchestrators of numerous biological processes. For example, the cardiomyocyte circadian clock modulates transcription, translation, posttranslational modifications, ion homeostasis, signaling cascades, metabolism, and contractility of the heart over the course of the day. Circadian clocks are composed of more than 10 interconnected transcriptional modulators, all of which have the potential to influence the cardiac transcriptome (and ultimately cardiac processes). These transcriptional modulators include BMAL1 and REV-ERBa/b; BMAL1 induces REV-ERBa/b, which in turn feeds back to inhibit BMAL1. Previous studies indicate that cardiomyocyte-specific BMAL1 knockout (CBK) mice exhibit a dysfunctional circadian clock (including decreased REV-ERBa/b expression) in the heart, associated with abnormalities in cardiac mitochondrial function, metabolism, signaling, and contractile function. Here, we hypothesized that decreased REV-ERBa/b activity is responsible for distinct phenotypic alterations observed in CBK hearts. To test this hypothesis, CBK (and littermate control) mice were administered with the selective REV-ERBa/b agonist, SR-9009 (100mg/Kg/day, for 8-days). SR-9009 administration was sufficient to normalize cardiac glycogen synthesis rates, cardiomyocyte size, interstitial fibrosis, and contractility in CBK hearts (without influencing mitochondrial complex activities, nor normalizing substrate oxidation and Akt/mTOR/GSK3b signaling). Collectively, these observations highlight a role for REV-ERBa/b as a mediator of a subset of circadian clock-controlled processes in the heart.
Dietary Calcium Levels Reduce the Efficacy of One Alpha-Hydroxycholecalciferol in Phosphorus-Deficient Diets of Broilers

One alpha-hydroxycholecalciferol (1α-OH D3), an analog of cholecalciferol (vitamin D3), improves growth performance and phosphorus retention in broilers. In the present study, we investigate the effects of dietary calcium (Ca) levels on the efficacy of 1α-OH D3 in the phosphorus (P)-deficient corn-soybean meal diets of 1to 21-d-old broilers. Four hundred female Ross 308 broilers, 1-d-old, were randomly allotted to 10 treatments with 4 cages of 10 birds each. A 5×2 factorial experiment was designed to test 0.40, 0.60, 0.80, 1.00, and 1.20% Ca combined with 0 and 5 μg/kg of 1α-OH D3 in a basal diet (0.25% non-phytate phosphorus (NPP), 0.48% total phosphorus (tP)) without vitamin D3. The lowest levels of body weight gain (BWG), feed intake (FI), feed efficiency (FE), tibia quality (except of ash and P), as well as the highest value of mortality, were observed at 0.40% Ca. Additional Ca corrected the Ca deficiency and eventually 1.2% Ca caused a P deficiency. The addition of 1α-OH D3 improved BWG, FI, FE, serum inorganic phosphate concentration, tP retention, tibia weight, length, breaking-strength, and content of ash, Ca, and P, and decreased mortality. However, 1α-OH D3 efficacy responded negatively to dietary Ca level. These results indicate that 1α-OH D3 exerts the highest activities at lower concentration of dietary Ca.
Effects of a Novel Psychomotor Stabilizer, IRL790, on Biochemical Measures of Synaptic Markers and Neurotransmission

The novel small-molecule psychomotor stabilizer, IRL790, is currently in clinical trial for treatment of levodopa-induced dyskinesia and psychosis in patients with Parkinson disease. Here, we used naïve mice to investigate the effects of acute systemic administration of IRL790 on protein levels and phosphorylation states of proteins relevant for synaptic plasticity and transmission. IRL790 increased pro–brain-derived neurotrophic factor protein levels and phosphorylation at Ser1303 of the N-methyl-D-aspartate (NMDA) subtype 2B glutamate receptor (NR2B) in prefrontal cortex. IRL790 also increased the phosphorylation states at Ser19, Ser31, and Ser40, respectively, of tyrosine hydroxylase in striatum. IRL790 reduced protein levels of the NR2B receptor in striatum but not in prefrontal cortex. Taken together, we report that systemically administered IRL790 rapidly elicits changes in protein level and phosphorylation state of proteins associated with a beneficial effect on synaptic markers and neurotransmission. SIGNIFICANCE STATEMENT The novel small-molecule psychomotor stabilizer, IRL790, is currently in clinical trial for treatment of levodopa-induced dyskinesia and psychosis in patients with Parkinson disease. In this study, we report that systemically administered IRL790 rapidly elicits changes in protein level and phosphorylation state of proteins associated with a beneficial effect on synaptic markers and neurotransmission.
The Effects of Postprandial Resistance Exercise on Blood Glucose and Lipids in Prediabetic, Beta-Thalassemia Major Patients

Insulin resistance and diabetes mellitus are common consequences of iron overload in the pancreas of beta-thalassemia major (BTM) patients. Moreover, postprandial blood glucose elevations are linked to major vascular complications. The purpose of this study was to investigate the effects of a bout of acute resistance exercise following breakfast consumption of glucose and fat on the metabolism in prediabetic, BTM patients. Six patients underwent two trials (exercise and control) following breakfast consumption (consisting of approximately 50% carbohydrates, 15% proteins, 35% fat), in a counterbalanced order, separated by at least three days. In an exercise trial, patients performed chest and leg presses (3 sets of 10 repetitions maximum/exercise), while in the control trial they rested. Blood samples were obtained in both trials at: pre-meal, 45 min post-meal (pre-exercise/control), post-exercise/control, 1 h post-exercise/control, 2 h post-exercise/control and 24 h post-exercise/control. Blood was analysed for glucose and lipids (total cholesterol, High Density Lipoprotein-cholesterol, Low Density Lipoprotein-cholesterol, triglycerides). Blood glucose levels increased significantly 45 min following breakfast consumption. Blood glucose and lipids did not differ between trials at the same time points. It seems that a single bout of resistance training is not sufficient to improve blood glucose and fat levels for the subsequent 24-h post-exercise period in prediabetic, BTM patients.