Miracle-dz/UniFAR-FTUs huggingface dataset:
Concordant Evidence-Based Interventions in Cardiac and Pulmonary Rehabilitation Guidelines

Chronic conditions such as chronic obstructive pulmonary disease (COPD) and cardiovascular disease (CVD) contribute to a significant burden to patients and many experience a reduction in physical functioning, psychological health, and quality of life. The sentinel symptom for COPD and CVD is breathlessness. Rehabilitation programs have been proven to reduce disease symptoms and increase levels of physical and psychological wellness. Pulmonary and cardiac rehabilitation programs have been recommended in international and national guidelines for managing COPD and CVD. Given that these programs seek to reduce breathlessness and improve the physical and psychological functioning of people with COPD and CVD, this review examines the concordant evidence-based interventions in rehabilitation guidelines. The findings of this review indicate that there was concordance in the program design, location of programs, types of health professionals involved in program delivery, assessments of patient at commencement and completion of program, and the delivery of educational topics with minor deviations that were related to disease-specific topics. Apart from disease-specific recommendations, the main divergence from rehabilitation guidelines was found to be dietary screening, inspiratory muscle training, and psychological assessments in evidence-based recommendations for cardiac and pulmonary programs.
Compliance with ecological momentary assessment protocols in substance users: a meta‐analysis

Abstract Background and Aims While there are considerable benefits to Ecological Momentary Assessment (EMA), poor compliance with assessment protocols has been identified as a limitation, particularly in substance users. Our aim was to identify the pooled compliance rate of EMA studies in substance users and examine variables that may influence compliance with EMA protocols, such as the length and frequency of assessments. Design A meta‐analysis and meta‐regression of all possible studies (randomized controlled trials and longitudinal) which incorporated EMA protocols, examining substance use. Setting Studies took place from 1998 to 2017, in numerous countries world‐wide. Participants One hundred and twenty‐six studies were identified, contributing a total of 19 431 participants (52.32% male, mean age = 28.86). Measurements Compliance data, the proportion of responses to the study protocol, were extracted from each study alongside prompt frequency, total length of assessment period, substance use population and device used to administer EMA prompts. Findings The pooled compliance rate across all studies was 75.06% [95% confidence interval (CI) = 72.37%, 77.65%]. There was no evidence that compliance rates were significantly associated with prompt frequency [Q(3) = 7.35, P = 0.061], length of assessment period [Q(2) = 2.40, P = 0.301], substance type [Q(3) = 6.30, P = 0.098] or device administration [Q(4) = 4.28, P = 0.369]. However, dependent samples (69.80%) had lower compliance rates than non‐dependent samples [76.02%; Q(1) = 4.13, P = 0.042]. Conclusions The pooled compliance rate for Ecological Momentary Assessment studies in substance‐using populations from 1998 to 2017 was lower than the recommended rate of 80%, and was not associated with frequency or duration of assessments.
A systematic review of measures of adherence to physical exercise recommendations in people with stroke

Objective: To review methods for measuring adherence to exercise or physical activity practice recommendations in the stroke population and evaluate measurement properties of identified tools. Data sources: Two systematic searches were conducted in eight databases (MEDLINE, CINAHL, PsycINFO, Cochrane Library of Systematic Reviews, Sports Discus, PEDro, PubMed and EMBASE). Phase 1 was conducted to identify measures. Phase 2 was conducted to identify studies investigating properties of these measures. Review methods: Phase 1 articles were selected if they were published in English, included participants with stroke, quantified adherence to exercise or physical activity recommendations, were patient or clinician reported, were defined and reproducible measures and included patients >18 years old. In phase 2, articles were included if they explored psychometric properties of the identified tools. Included articles were screened based on title/abstract and full-text review by two independent reviewers. Results: In phase 1, seven methods of adherence measurement were identified, including logbooks (n = 16), diaries (n = 18), ‘record of practice’ (n = 3), journals (n = 1), surveys (n = 2) and questionnaires (n = 4). One measurement tool was identified, the Physical Activity Scale for Individuals with Physical Disabilities (n = 4). In phase 2, no eligible studies were identified. Conclusion: There is not a consistent measure of adherence that is currently utilized. Diaries and logbooks are the most frequently utilized tools.
The Use of Unmanned Aerial Vehicles to Estimate Direct Tangible Losses to Residential Properties from Flood Events: A Case Study of Cockermouth Following the Desmond Storm

Damage caused by flood events is expected to increase in the coming decades driven by increased land use pressures and climate change impacts. The insurance sector needs accurate and efficient loss adjustment methodologies for flood events. These can include remote sensing approaches that enable the rapid estimation of (i) damage caused to property as well as (ii) the number of affected properties. Approaches based on traditional remote sensing methods have limitations associated with low-cloud cover presence, oblique viewing angles, and the resolution of the geomatic products obtained. Unmanned aerial vehicles (UAVs) are emerging as a potential tool for post-event assessment and provide a means of overcoming the limitations listed above. This paper presents a UAV-based loss-adjustment framework for the estimation of direct tangible losses to residential properties affected by flooding. For that purpose, features indicating damage to property were mapped from UAV imagery collected after the Desmond storm (5 and 6 December 2015) over Cockermouth (Cumbria, UK). Results showed that the proposed framework provided an accuracy of 84% in the detection of direct tangible losses compared with on-the-ground household-by-household assessment approaches. Results also demonstrated the importance of pluvial and, from eye witness reports, lateral flow flooding, with a total of 168 properties identified as flooded falling outside the fluvial flood extent. The direct tangible losses associated with these additional properties amounted to as high as £3.6 million. The damage-reducing benefits of resistance measures were also calculated and amounted to around £4 million. Differences in direct tangible losses estimated using the proposed UAV approach and the more classic loss-adjustment methods relying on the fluvial flood extent was around £1 million—the UAV approach providing the higher estimate. Overall, the study showed that the proposed UAV approach could make a significant contribution to improving the estimation of the costs associated with urban flooding, and responses to flooding events, at national and international levels.
Continued vs. interrupted direct oral anticoagulants at the time of device surgery, in patients with moderate to high risk of arterial thrombo-embolic events (BRUISE CONTROL-2)

Aims Guidelines recommend warfarin continuation rather than heparin bridging for pacemaker and defibrillator surgery, after the BRUISE CONTROL trial demonstrated an 80% reduction in device pocket haematoma with this approach. However, direct oral anticoagulants (DOACs) are now used to treat the majority of patients with atrial fibrillation. We sought to understand the best strategy to manage the DOACs at the time of device surgery and specifically hypothesized that performing device surgery without DOAC interruption would result in a reduced haematoma rate. Methods and results We randomly assigned patients with atrial fibrillation and CHA2DS2-VASc score ≥2, to continued vs. interrupted DOAC (dabigatran, rivaroxaban, or apixaban). The primary outcome was blindly evaluated, clinically significant device pocket haematoma: resulting in re-operation, interruption of anticoagulation, or prolonging hospital stay. In the continued arm, the median time between pre- and post-operative DOAC doses was 12 h; in the interrupted arm the median time was 72 h. Clinically significant haematoma occurred in of 7 of 328 (2.1%; 95% CI 0.9-4.3) patients in the continued DOAC arm and 7 of 334 (2.1%; 95% CI 0.9-4.3) patients in the interrupted DOAC arm (P = 0.97). Complications were uncommon, and included one stroke and one symptomatic pericardial effusion in each arm. Conclusions These results suggest that, dependent on the clinical scenario, either management strategy (continued DOAC or interrupted DOAC) might be reasonable, at least for patients similar to those enrolled in our trial.
Influence of myocardial count on phase dyssynchrony analysis of gated myocardial perfusion single-photon emission computed tomography

Objectives Drugs and acquisition times for gated myocardial perfusion single-photon emission computed tomography scintigraphy vary depending on the facility. Even if the same examination is performed in the same facility, the acquisition count differs for each examination because factors such as the patient’s age, stress protocol of the patient, the biological half-life of the stress agent, and the patient’s response are different. We aimed to evaluate the differences in acquisition counts on the effect of left ventricular function and phase analysis indices. Materials and methods A gated myocardial perfusion phantom was used. The acquisition times acquired were varied (nine steps from 3 to 51 s per view). The myocardial average count per pixel of the left anterior oblique (LAO) of 45° of projection data were 9.4, 17.8, 28.7, 47.1, 67.1, 97.7, 122.7, 174.4, and 254.0 counts per view. We used the count value of LAO of 45° of projection data to find the lowest count that the left ventricular function and phase analysis indices can accurately calculate. The left ventricular function indices evaluated were the left ventricular ejection fraction (LVEF), end-diastolic volume (EDV), and end-systolic volume (ESV). The bandwidth, phase SD, and entropy were evaluated as phase analysis indices. Results Functional analysis: LVEF and EDV showed constant values even when the collection count changed (%coefficient of variation (CV) of LVEF=2.1%, %CV of EDV=3.9%). The ESV value was large when the lowest count was obtained (9.4 counts per pixel per view), which caused %CV of ESV to be greater than that of LVEF and EDV (%CV of EDV=7.8%). Phase analysis indices: The difference between the highest and lowest values was that the bandwidth was 100.0%, phase SD was 62.0%, and entropy was 58.3%. Phase analysis indices declined as a function of increasing acquisition time. Conclusion To accurately calculate left ventricular function, the myocardial counts of LAO of 45° of projection data should be at least 17.8 average counts per pixel per view. To accurately calculate the phase analysis index, the myocardial counts of LAO of 45° of projection data should be at least 67.1 average counts per pixel per view.
Comparison and Bias Correction of TMPA Precipitation Products over the Lower Part of Red-Thai Binh River Basin of Vietnam

As the limitation of rainfall collection by ground measurement has been widely recognized, satellite-based rainfall estimate is a promising high-resolution alternative in both time and space. This study is aimed at exploring the capacity of the satellite-based rainfall product Tropical Rainfall Measurement Mission (TRMM) Multi-satellite Precipitation Analysis (TMPA), including 3B42V7 research data and its real-time 3B42RT data, by comparing them against data from 29 ground observation stations over the lower part of the Red–Thai Binh River Basin from March 2000 to December 2016. Various statistical metrics were applied to evaluate the TMPA products. The results showed that both 3B42V7 and 3B42RT had weak relationships with daily observations, but 3B42V7 data had strong agreement on the monthly scale compared to 3B42RT. Seasonal analysis showed that 3B42V7 and 3B42RT underestimated rainfall during the dry season and overestimated rainfall during the wet season, with high bias observed for 3B42RT. In addition, detection metrics demonstrated that TMPA products could detect rainfall events in the wet season much better than in the dry season. When rainfall intensity was analyzed, both 3B42V7 and 3B42RT overestimated the no rainfall event during the dry season but underestimated these events during the wet season. Finally, based on the moderate correlation between climatology–topography characteristics and correction factors of linear-scaling (LS) approach, a set of multiple linear models was developed to reduce the error between TMPA products and the observations. The results showed that climatology–topography-based linear-scaling approach (CTLS) significantly reduced the percentage bias (PBIAS) score and moderately improved the Nash–Sutcliffe efficiency (NSE) score. The finding of this paper gives an overview of the capacity of TMPA products in the lower part of the Red–Thai Binh River Basin regarding water resource applications and provides a simple bias correction that can be used to improve the correctness of TMPA products.
Cortical correlates of the auditory frequency-following and onset responses: EEG and fMRI evidence

The frequency following response (FFR) is a measure of the brain’s periodic sound encoding. It is of increasing importance for studying the human auditory nervous system due to numerous associations with auditory cognition and dysfunction. Although the FFR is widely interpreted as originating from brainstem nuclei, a recent study using magnetoencephalography (MEG) suggested that there is also a right-lateralized contribution from the auditory cortex at the fundamental frequency (Coffey et al., 2016c). Our objectives in the present work were to validate and better localize this result using a completely different neuroimaging modality, and document the relationships between the FFR and the onset response, and cortical activity. Using a combination of electroencephalography, fMRI, and diffusion-weighted imaging, we show that activity in the right auditory cortex is related to individual differences in FFR-f0 strength, a finding that was replicated with two independent stimulus sets, with and without acoustic energy at the fundamental frequency. We demonstrate a dissociation between this FFR-f0-sensitive response in the right and an area in left auditory cortex that is sensitive to individual differences in the timing of initial response to sound onset. Relationships to timing and their lateralization are supported by parallels in the microstructure of the underlying white matter, implicating a mechanism involving neural conduction efficiency. These data confirm that the FFR has a cortical contribution, and suggest ways in which auditory neuroscience may be advanced by connecting early sound representation to measures of higher-level sound processing and cognitive function. Significance Statement The frequency following response (FFR) is an electroencephalograph signal that is used to explore how the auditory system encodes temporal regularities in sound, and which is related to differences in auditory function between individuals. It is known that brainstem nuclei contribute to the FFR, but recent findings of an additional cortical source are more controversial. Here, we use functional MRI to validate and extend the prediction from magnetoencephalography data of a right auditory cortex contribution to the FFR. We also demonstrate a dissociation between FFR-related cortical activity from that related to the latency of the response to sound onset, which is found in left auditory cortex. The findings provide a clearer picture of cortical processes for analysis of sound features.
Incidence of and risk factors for development of oral mucositis in outpatients undergoing cancer chemotherapy

AIM The aims of the study are to determine the incidence of oral mucositis, the stage of the condition, risk factors, and other oral complications in patients receiving outpatient chemotherapy and to evaluate the factors that have an impact on these. METHODS The study included 147 patients undergoing outpatient cancer chemotherapy at the Chemotherapy Unit of a University Hospital between February and April 2015. We used a questionnaire and the World Health Organization "Mucositis Grading Scale". Chi-squared tests were used to determine the relationships between factors, and multiple logistic regression analysis was employed to explore predictive factors. RESULTS The frequency of oral mucositis was 51.7%. The most common oral problems were mouth dryness (55.1%), a reduced/changed sense of taste (52.4%), and a lack of appetite (47.6%). Logistic regression analysis showed that the risk factors for oral mucositis were advanced age, a lack of appetite, and the duration of chemotherapy. CONCLUSIONS As a result, half of all patients undergoing outpatient cancer chemotherapy developed oral mucositis. Patients are unable to adequately prevent oral mucositis and carry out oral care. It is recommended that more studies be conducted in outpatient units to evaluate predictive factors for oral mucositis.
Emergency Department and Primary Care Use in Massachusetts 5 Years After Health Reform

Objective: Conceptually, access to primary care (through insurance) should reduce emergency department (ED) visits for primary care sensitive (PCS) conditions. We sought to identify characteristics of insured Massachusetts residents associated with PCS ED use, and compare such use for public versus private insurees. Population and Setting: People under age 65 in the Massachusetts All-Payer Claims Data, 2011–2012. Study Design: Retrospective, observational analysis of PCS ED use with nonurgent, urgent/primary care treatable, and urgent/potentially avoidable visits being considered PCS. We predicted utilization in 2012 using multivariable regression models and data available in 2011 administrative records. Principal Findings: Among 2,269,475 nonelderly Massachusetts residents, 40% had public insurance. Among public insurees, PCS ED use was higher than for private (mean, 36.5 vs. 9.0 per 100 persons; adjusted risk ratio, 2.53; 95% confidence limits, 2.49–2.56), while having any primary care visit was less common (70% vs. 83%), as was having any visit to one’s own (attributed) primary care provider (38% vs. 44%). Conclusions: Public insurance was associated with less access to primary care and more PCS ED use; statewide labor shortages and low reimbursement rates from public insurance may have provided inadequate access to care that might otherwise have helped reduce PCS ED use.
Delineation of Built-Up Areas from Very High-Resolution Satellite Imagery Using Multi-Scale Textures and Spatial Dependence

Very high spatial resolution (VHR) satellite images possess several advantages in terms of describing the details of ground targets. Extracting built-up areas from VHR images has received increasing attention in practical applications, such as land use planning, urbanization monitoring, geographic information database update. In this study, a novel method is proposed for built-up area detection and delineation on VHR satellite images, using multi-resolution space-frequency analysis, spatial dependence modelling and cross-scale feature fusion. First, the image is decomposed by multi-resolution wavelet transformation, and then the high-frequency information at different levels is employed to represent the multi-scale texture and structural characteristics of built-up areas. Subsequently, the local Getis-Ord statistic is introduced to model the spatial patterns of built-up area textures and structures by measuring the spatial dependence among frequency responses at different spatial positions. Finally, the saliency map of built-up areas is produced using a cross-scale feature fusion algorithm, followed by adaptive threshold segmentation to obtain the detection results. The experiments on ZY-3 and Quickbird datasets demonstrate the effectiveness and superiority of the proposed method through comparisons with existing algorithms.
Flood Risk Perceptions and Insurance Choice: Do Decisions in the Floodplain Reflect Overoptimism?

In the presence of rare disasters, risk perceptions may not always align with actual risks. These perceptions can nevertheless influence an individual's willingness to mitigate risks through activities such as purchasing flood insurance. In a survey of Maryland floodplain residents, we find that stated risk perceptions predict voluntary flood insurance take‐up, while perceptions themselves varied widely among surveyed residents, owing in large part to differences in past flood experience. We use a formal test for overoptimism in risk perceptions and find that, on aggregate, floodplain residents are overly optimistic about flood risks.
Association between 12‐hr shifts and nursing resource use in an acute hospital: Longitudinal study

Abstract Aim To evaluate whether ≥12‐hr shifts are associated with a decrease in resource use, in terms of care hours per patient day and staffing costs per patient day. Background Nurses working long shifts may become less productive and no research has investigated whether potential cost savings are realized. Method A retrospective longitudinal study using routinely collected data from 32 wards within an English hospital across 3 years (1 April 2012–31 March 2015). There were 24,005 ward‐days. Hierarchical linear mixed models measured the association between the proportion of ≥12‐hr shifts worked on a ward‐day, care hours per patient day and staffing costs per patient day. Results Compared with days with no ≥12‐hr shifts, days with between 50% and 75% ≥12‐hr shifts had more care hours per patient day and higher costs (estimate for care hours per patient day: 0.32; 95% CI: 0.28–0.36; estimate for staffing costs per patient day: £8.86; 95% CI: 7.59–10.12). Conclusions We did not find reductions in total care hours and costs associated with the use of ≥12‐hr shifts. The reason why mixed shift patterns are associated with increased cost needs further exploration. Implications for Nursing Management Increases in resource use could result in additional costs or loss of productivity for hospitals. Implementation of long shifts should be questioned.
Echocardiographic diastolic function evolution in patients with an anterior Q‐wave myocardial infarction: insights from the REVE‐2 study

Myocardial fibrosis plays a key role in the development of adverse left ventricular remodelling after myocardial infarction (MI). This study aimed to determine whether the circulating levels of BNP, collagen peptides, and galectin‐3 are associated with diastolic function evolution (both deterioration and improvement) at 1 year after an anterior MI.