Miracle-dz/UniFAR-FTUs huggingface dataset:
Creativity in the lives of English teachers: voices through found poetry

ABSTRACT This arts-based research explores the place of creativity in the lives of a focus group of teachers of English in an English secondary school who work within an increasingly performative educational system. As well as interrogating the place of creativity in their lives, the study explores how found poetry can be used as a research method to collate, analyse and then represent data. The poems are produced from semi-structured individual interviews. The participants were able to scrutinise and reflect upon the poems before returning for a second interview. This process helped strengthen the findings and gave a deeper understanding of their experiences regarding creativity. The findings suggest that the participants have limited space to be creative, or to think differently in their teaching practice. The limited space to be creative comes from normalising practices of a performance culture, but the restrictions are extrinsic and internally imposed by the participants.
Morphometrical, Morphological, and Immunocytochemical Characterization of a Tool for Cytotoxicity Research: 3D Cultures of Breast Cell Lines Grown in Ultra-Low Attachment Plates

Three-dimensional cell cultures may better mimic avascular tumors. Yet, they still lack characterization and standardization. Therefore, this study aimed to (a) generate multicellular aggregates (MCAs) of four breast cell lines: MCF7, MDA-MB-231, and SKBR3 (tumoral) and MCF12A (non-tumoral) using ultra-low attachment (ULA) plates, (b) detail the methodology used for their formation and analysis, providing technical tips, and (c) characterize the MCAs using morphometry, qualitative cytology (at light and electron microscopy), and quantitative immunocytochemistry (ICC) analysis. Each cell line generated uniform MCAs with structural differences among cell lines: MCF7 and MDA-MB-231 MCAs showed an ellipsoid/discoid shape and compact structure, while MCF12A and SKBR3 MCAs were loose, more flattened, and presented bigger areas. MCF7 MCAs revealed glandular breast differentiation features. ICC showed a random distribution of the proliferating and apoptotic cells throughout the MCAs, not fitting in the traditional spheroid model. ICC for cytokeratin, vimentin, and E-cadherin showed different results according to the cell lines. Estrogen (ER) and progesterone (PR) receptors were positive only in MCF7 and human epidermal growth factor receptor 2 (HER-2) in SKBR3. The presented characterization of the MCAs in non-exposed conditions provided a good baseline to evaluate the cytotoxic effects of potential anticancer compounds.
Systemic lupus erythematosus in pregnancy

When a woman is known to have systemic lupus erythematosis, planning and preparation can improve the outcome of pregnancy and reduce the severity of some of the potential problems. All treatment options have risks but these risks have to be balanced against the risks of no treatment or, ‘too late’ treatment. In pregnancy, close fetal surveillance is important. Once there are definite signs of fetal harm this cannot always be corrected and late management decisions can only institute rescue. Urgent premature delivery is a frequent phenomenon. Proactive medical care of the mother, together with accurate information about the state of the baby, may reduce the frequency of sudden or early delivery thereby assisting neonatal management. Currently, some risks such as neonatal lupus with congenital heart block, retain a high mortality. The construction of an agreed detailed prospective management plan, understood by all those involved, can lead to increased satisfaction with the care process and a better outcome.
Football pitch condition analysis based on k-means clustering

Football, a highly popular sport all over the world, requires that professional footballers practice it on a field of play in ideal conditions, which, among other things, includes the usage and maintenance of healthy natural grass. In this study, we present an unsupervised allocator strategy for image analysis of football pitches that uses k-means clustering and color comparison to assess whether a playing field is in good or bad condition. Our approach considers proportions of dominant RGB colors for automatized decision-making. For such endeavour, a prototype was developed and tested with a series of images, with the findings being compared to those expected.
Bidentate Donor-Functionalized N-Heterocyclic Carbenes: Valuable Ligands for Ruthenium-Catalyzed Transfer Hydrogenation

Ruthenium complexes are by far the most studied compounds that catalyze hydrogen transfer reactions. In this review, we describe the use in this field of ruthenium complexes bearing bidentate donor-functionalized N-heterocyclic carbene ligands. The review specifically covers the application in transfer hydrogenations of (κ2-CNHC,Y)-ruthenacyclic compounds where the Y donor atom is a N, P, O, or S atom, and where the N-heterocyclic carbene ligand is a classical imidazol-2-ylidene, a benzimidazol-2-ylidene, a mesoionic 1,2,3-triazolylidene, or an imidazol-4-ylidene ligand. Tridentate donor-functionalized N-heterocyclic carbene complexes thus fall outside the scope of the review. Applications in (asymmetric) transfer hydrogenation of ketones, aldehydes, imines, alkenes, and nitrobenzene are discussed.
Three-year results of combined pars plana vitrectomy and phacoemulsification in diabetic vitreous hemorrhage

Aim: The purpose of this study was to evaluate the efficacy and safety of complications following combined pars plana vitrectomy and phacoemulsification surgery of the eyes for the management of vitreous hemorrhage due to proliferative diabetic retinopathy as well as pronounced cataracts. Material and Method: Phacoemulsification and 23G pars plana vitrectomy procedures were performed for the management of vitreous hemorrhage and cataracts. Age, gender, best-corrected visual acuity before and after surgery, and intra- and post-operative complications were recorded in patients with cataracts who underwent surgery due to vitreous hemorrhage. Results: A total of 40 eyes of 40 patients, 22 females (55%) and 18 males, were included in the study. The mean age was 58.7±7.1 (44–76) years. Logmar visual acuity changed from a mean of 2.82±0.5 preoperatively to a mean of 0.7±0.6 postoperatively. Visual acuity increased in 38 eyes (95%) postoperatively. No reduction in visual acuity was observed in any eye. Complications associated with surgery included transient intraocular pressure increase (12 eyes), hyphema (2 eyes), posterior capsule rupture (1 eye), anterior chamber fibrin exudation (4 eyes), neovascular glaucoma (1 eye), vitreous hemorrhage (4 eyes), retinal detachment (1 eye), and posterior capsule opacification (2 eyes). Conclusion: It was found that combined phacoemulsification and PPV surgery was safe and effective in patients with proliferative diabetic retinopathy. Combined phaco-vitrectomy is a reliable method with a minimum complication profile and prevents the need for subsequent cataract surgery.
Translanguaging Practice in Higher Education: Lecturers’ and Students’ Perspectives

The notion of Translanguaging is not something new in the context of EFL classroom but, both lecturer and student may not be familiar with the basic concept and how it is implemented in the classroom, that is why this paper is presented as argumentative essay focusing to explore the basic notion of Translanguaging from the perspective of lecture and students. It tried to explain about challenges and opportunities of bringing about Translanguaging to classroom practice. From the theories and several studies discussing about the implementation of Translanguaging, it is found that several findings support the practice of Translanguaging, while others found its drawback so that it is worth investigating to see on the lecturers' and students' perspectives. Since Translanguaging changes the way people think about second language learning, it needs to be viewed by students as both a threat and an opportunity. Lecturers, on the other hand, must see it as a university-wide theme applied to Translanguaging through active and collaborative learning.
Intra/inter-rater and parallel-forms reliability of the three instruments for the assessment of ankle dorsiflexion range of motion and degree of asymmetry during the weight-bearing lunge test

Background: This study sought to evaluate the intra- and inter-rater reliability of the three instruments for the measurement of ankle dorsiflexion (ADF) range of motion (ROM) and degree of asymmetry during the Weight-Bearing Lunge Test (WBLT) and to examine the agreement between them in asymptomatic and symptomatic subjects. Methods: Thirty-two healthy subjects and thirty-three subjects with pathologies were measured on two occasions by two different examiners and using different methods while performing the WBLT. Results: Intra- and inter-rater reliability of Veloflex showed good to excellent values (ICC’s > 0.88) for both the measurement of ADF-ROM and degree of asymmetry in symptomatic and asymptomatic subjects. In addition, Veloflex and the tape measure showed acceptable agreement between their values in symptomatic subjects. Conclusion: Veloflex is reliable for the measurement of ADF-ROM and the degree of asymmetry in symptomatic and asymptomatic subjects. This system may be exchanged by the tape measure, however, exchanging Veloflex with the Dorsiflex app is not recommended.
MFNet: Multi-Feature Fusion Network for Real-Time Semantic Segmentation in Road Scenes

Although high-accuracy networks have been applied to semantic segmentation at present, their inference speeds remain slow. A trade-off between accuracy and speed is demanded for real-time applications. To approach this problem, we propose Multi-Feature Fusion Network (MFNet) with real-time efficient prediction capacity. MFNet adopts three branches (attention, semantic and spatial information) to capture low-level and high-level features. Additionally, MFNet exerts asymmetric factorized (AF) blocks to extract local and long-range features. As a result, without any pre-training or post-processing, MFNet using only 1.34 M parameters, achieves 72.1% mean intersection over union (mIoU) on the Cityscapes test set at a speed of 116 frames per second (FPS), with $512\times 1024$ high resolution on a single Titan Xp graphics card. Our network’s performance stands out from other state-of-the-art networks on four datasets (Cityscapes, CamVid, KITTI, and Gatech).
Modulation of Multiple Gene Clusters’ Expression by the PAS-LuxR Transcriptional Regulator PteF

PAS-LuxR transcriptional regulators are conserved proteins governing polyene antifungal biosynthesis. PteF is the regulator of filipin biosynthesis from Streptomyces avermitilis. Its mutation drastically abates filipin, but also oligomycin production, a macrolide ATP-synthase inhibitor, and delays sporulation; thus, it has been considered a transcriptional activator. Transcriptomic analyses were performed in S. avermitilis ΔpteF and its parental strain. Both strains were grown in a YEME medium without sucrose, and the samples were taken at exponential and stationary growth phases. A total of 257 genes showed an altered expression in the mutant, most of them at the exponential growth phase. Surprisingly, despite PteF being considered an activator, most of the genes affected showed overexpression, thereby suggesting a negative modulation. The affected genes were related to various metabolic processes, including genetic information processing; DNA, energy, carbohydrate, and lipid metabolism; morphological differentiation; and transcriptional regulation, among others, but were particularly related to secondary metabolite biosynthesis. Notably, 10 secondary metabolite gene clusters out of the 38 encoded by the genome showed altered expression profiles in the mutant, suggesting a regulatory role for PteF that is wider than expected. The transcriptomic results were validated by quantitative reverse-transcription polymerase chain reaction. These findings provide important clues to understanding the intertwined regulatory machinery that modulates antibiotic biosynthesis in Streptomyces.
Internal Model-Based Active Damping Strategy for a Back-to-Back Modular Multilevel Converter System for Advanced Grid Support

The proposed work focuses on the possibility of achieving the reduction in the size of the interfacing filter for the grid connection for a back-to-back modular multilevel converter system with the use of third order LCL filters. To achieve the same attenuation, it is possible to reduce the size of the interfacing filters by the usage of third-order filters; however, this kind of filtering comes with the limitation of having sustained oscillations caused by lack of damping especially during transient changes. Therefore, this work proposes, a methodology based on the principle of internal model to nullify these unwanted oscillations. The third-order system is modeled inside the microcontroller with the damping enabled. The error between the output from the model and the actual output are compared and the error is used to accomplish the active damping strategy. The proposed architecture is verified via computer simulations based on the MATLAB/Simulink domain. Various case study results and discussions are presented in this paper.
Effect of Dielectric Relaxation of Epoxy Resin on Dielectric Loss of Medium-Frequency Transformer

Epoxy resin (EP) is a typical and widely used insulating material for medium-frequency transformers (MFTs). The dielectric loss of EP is one of the key variables in the design and operation of MFT. In this article, six types of epoxy/anhydride systems are prepared, and the dielectric loss of MFT is calculated by finite element method (FEM) analysis based on broadband dielectric spectroscopy measurements. The material dependence of the dielectric loss of MFT is investigated using dielectric spectroscopy and molecular dynamics simulations over a wide temperature and frequency range. The results show that the variation of dielectric loss with output power is attributed to the temperature characteristics of the imaginary part (<inline-formula> <tex-math notation="LaTeX">$\varepsilon ^{\prime \prime }$ </tex-math></inline-formula>) of complex permittivity. Compared to the dielectric loss at no-load state, the one at rated power is reduced by 5–10 W. The anhydride hardener containing benzene ring or a methyl substituent has an inhibitory effect on dielectric loss, and the EP cured by methyl nadic anhydride (MeNA) has the lowest dielectric loss (16.2 W) at rated power. The dielectric loss and overload characteristics of MFT are closely related to the <inline-formula> <tex-math notation="LaTeX">$\beta $ </tex-math></inline-formula>-relaxation and <inline-formula> <tex-math notation="LaTeX">$\alpha $ </tex-math></inline-formula>-relaxation of EP, respectively. The acid anhydride curing agent containing benzene ring or a methyl substituent reduces the temperature corresponding to the <inline-formula> <tex-math notation="LaTeX">$\beta $ </tex-math></inline-formula>-relaxation peak by more than 50 °C compared to the one without. The increased rigidity of the chain segment of EP makes the <inline-formula> <tex-math notation="LaTeX">$\beta $ </tex-math></inline-formula>-relaxation move to the low-temperature side, which is beneficial to suppress the dielectric loss. This article not only serves as a bridge among dielectric loss of MFT, dielectric spectroscopy, and molecular structure of EP but also lays a solid foundation for the selection of insulating materials for MFT.
Educação Inclusiva no Ensino de Ciências e de Química - Uma revisão da literatura sobre as propostas pedagógicas direcionadas a estudantes com desenvolvimento atípico

O presente artigo objetiva analisar como a perspectiva da Educação Inclusiva está sendo abordada nas pesquisas da área de Ensino de Ciências e de Química, para identificar propostas pedagógicas para estudantes com desenvolvimento atípico na dimensão cognitiva, como aqueles com deficiência intelectual ou múltiplas, síndromes, transtornos globais do desenvolvimento, altas habilidades/superdotação ou outro transtorno de aprendizagem. Para tanto, realizou-se uma revisão bibliográfica, do tipo estado do conhecimento, em periódicos classificados em estratos A1, A2 e B1 do Qualis/CAPES de 2016 na área de Ensino de Ciências, no período de publicações entre 2006 e maio de 2019. A análise qualitativa realizada revelou que 73 artigos apresentam o foco de interesse desta pesquisa, sendo que a maioria versa sobre as concepções e formação de professores e boa parte dos artigos são teóricos e poucos descrevem pesquisas no contexto escolar e sobre estratégias didáticas. Os resultados produzidos por categorias de análise evidenciam que mais da metade dos autores e das pesquisas executadas estão relacionados às instituições de ensino superior das regiões Sul e Sudeste. Sobre os princípios pedagógicos das sequências didáticas, percebe-se que a maioria utiliza recursos audiovisuais e materiais de leitura. Destaca-se a escassez de pesquisas quanto ao âmbito das concepções dos estudantes e aspectos cognitivos acerca de sua aprendizagem a partir da perspectiva inclusiva nas principais revistas da área, principalmente analisando experiências didáticas no Ensino de Ciências e Química. Dessa forma, salienta-se a necessidade de mobilizar novas pesquisas dessa natureza na área.
Preanalytical Pitfalls in Untargeted Plasma Nuclear Magnetic Resonance Metabolomics of Endocrine Hypertension

Despite considerable morbidity and mortality, numerous cases of endocrine hypertension (EHT) forms, including primary aldosteronism (PA), pheochromocytoma and functional paraganglioma (PPGL), and Cushing’s syndrome (CS), remain undetected. We aimed to establish signatures for the different forms of EHT, investigate potentially confounding effects and establish unbiased disease biomarkers. Plasma samples were obtained from 13 biobanks across seven countries and analyzed using untargeted NMR metabolomics. We compared unstratified samples of 106 PHT patients to 231 EHT patients, including 104 PA, 94 PPGL and 33 CS patients. Spectra were subjected to a multivariate statistical comparison of PHT to EHT forms and the associated signatures were obtained. Three approaches were applied to investigate and correct confounding effects. Though we found signatures that could separate PHT from EHT forms, there were also key similarities with the signatures of sample center of origin and sample age. The study design restricted the applicability of the corrections employed. With the samples that were available, no biomarkers for PHT vs. EHT could be identified. The complexity of the confounding effects, evidenced by their robustness to correction approaches, highlighted the need for a consensus on how to deal with variabilities probably attributed to preanalytical factors in retrospective, multicenter metabolomics studies.
Genotyping-by-Sequencing and Morphology Revealed the Role of Polyploidization and Hybridization in the Diversification of the Centaurea aspera L. Complex of Section Seridia (Juss.) DC. (Asteraceae)

Hybridization and polyploidy are major drivers of plant evolution. In Centaurea (Asteraceae), both mechanisms are frequent and lead to reticulate evolutions. However, in the Western Mediterranean section, Seridia studies are scarce. In this section, Centaurea aspera forms a complex including four European diploid and one Moroccan autotetraploid subspecies, an allopolyploid, and hybrids among them. Here, we aimed to delimit the different taxa, identify any introgressions, and discuss their evolutionary history. Samples of all taxa were analysed using 1688 SNPs obtained through GBS and were morphologically characterized. Three genetically well-differentiated clusters were observed, corresponding to the allopolyploid C. seridis, the diploid C. aspera and the cryptic autotetraploid C. aspera ssp. gentilii, which is proposed to be considered as a species. Centaurea seridis showed a high isolation by distance, a greater morphological variability, and a lack of interspecific gene flow. Diploid and autotetraploid C. aspera individuals were morphologically similar, and some introgressions were detected in Southern Spain, where new forms may promote diversification. This gene flow might have taken place during the Messinian and before autopolyploidization occurred in Morocco. In the C. aspera complex, current interspecific barriers are strong, while polyploidization may provide a better adaptation to drier environments.
Association between Health Literacy and Prevalence of Obesity, Arterial Hypertension, and Diabetes Mellitus

Background: Health literacy (HL) is linked to many health outcomes, including self-management of chronic diseases. The aim of this study was to assess the association of health literacy with the prevalence of obesity, arterial hypertension (AH), and type 2 diabetes mellitus (T2DM). Methods: This cross-sectional, single-center study included 500 patients (42.2% male and 57.8% females; median age, 63 years (interquartile range, 42–73)) hospitalized at General County Hospital in Požega, Croatia, between July and October 2020. The Short Assessment of Health Literacy for Croatian Adults (SAHLCA-50) questionnaire was used. Descriptive statistics (median with interquartile range (IQR), frequency, and percentages) and binary logistic regression were utilized. Results: Patients with AH had an inadequate level of health literacy as compared to those without AH (32 vs. 40 points; Mann–Whitney U test, p < 0.001). Patients with T2DM scored 31 points versus 39 points in patients without T2DM (Mann–Whitney U test, p < 0.001). Patients suffering from both AH and T2DM scored 31 points versus 33 points in those with either AH or T2DM and 41 points in patients without AH and T2DM (Kruskal–Wallis test, p < 0.001). There were no statistically significant differences in SAHLCA-50 scores according to the patient body mass index. Conclusions: An inadequate level of health literacy is significantly associated with AH and T2DM but not with obesity. Male gender, low level of education, rural place of residence, retirement, and older age are significant predictors of inadequate health literacy.
Intravascular Lithotripsy as a Novel Treatment Method for Calcified Unprotected Left Main Diseases—Comparison to Rotational Atherectomy—Short-Term Outcomes

Background: The unprotected calcified Left Main disease represents a high-risk subset for percutaneous coronary intervention (PCI), and it is associated with a higher number of periprocedural complications and an increased rate of in-stent thrombosis and restenosis. Adequate lesion preparation plays a crucial role in achieving a favorable PCI outcome. Rotational Atherectomy (RA) is a well-established plaque-modifying method; nevertheless, the data regarding the effectiveness of RA in LM diseases is scarce. Recently, the novel ShockWave-Intravascular-Lithotripsy(S-IVL) device has been introduced to the PCI armamentarium in order to modify the calcified plaque. Methods: We performed a retrospective evaluation of 44 consecutive subjects who underwent the LM-PCI, and who were supported by either the RA or S-IVL. Results: The Rota group consisted of 29 patients with a mean syntax score of 28.0 ± 7.5. The S-IVL group was composed of 15 subjects with a syntax score of 23.3 ± 13.0 There were no statistical differences regarding MACE between the RA and Shockwave arms of the in-hospital group (10.3% vs. 6.7%), or in the six month (17.2% vs. 13.3%) follow-up group. Conclusions: RA and S-IVL could be safe and effective therapeutic strategies for calcified LM disease. Further studies with a higher number of participants and longer follow-up times are warranted to establish the potential benefits of RA and S-IVL for the management of LM stenosis.