Miracle-dz/UniFAR-FTUs huggingface dataset:
Terapia de nutrição enteral: construção e validação de protocolo [Enteral nutrition therapy: protocol construction and validation] [Terapia de nutrición enteral: construcción y validación de protocolo]

Objetivo: construir e validar um protocolo de terapia de nutricao enteral para pacientes adultos em uso de sonda enteral. Metodo: trata-se de um estudo descritivo em que se realizou uma revisao da literatura a respeito da tematica para construcao do instrumento e posterior validacao por especialistas. Participaram da fase de validacao 15 especialistas e os dados foram coletados entre junho e setembro de 2012, por meio de um formulario contendo dados referentes aos especialistas e dados avaliativos do protocolo. Resultado: o protocolo final resultou em duas secoes com seis dominios na primeira secao e seis na segunda. Apos sua construcao, realizou-se a validacao de aparencia e de conteudo, com obtencao de um indice de concordância de 0,837, considerado como de confiabilidade alta. Conclusao: o protocolo e valido e aplicavel na pratica, capaz de subsidiar desenhos de intervencao e de eleger a melhor forma de atuacao da enfermagem. ABSTRACT Objective: to develop and validate a protocol for enteral nutrition therapy for adult patients on enteral tube. Method: this descriptive study involved a literature review on the subject in order to construct the instrument and for its subsequent validation by experts. Fifteen experts participated in the validation, and data were collected between June and September 2012 using a form containing data on the experts and protocol evaluative data. Results: the final protocol resulted in two sections, each with six domains. After construction, protocol appearance and content validation returned a 0.837 rate of agreement, which is considered high reliability. Conclusion: the protocol is valid, applicable in practice, and able to inform intervention designs and choice of the best nursing practice. RESUMEN Objetivo: desarrollar y validar un protocolo de terapia de nutricion enteral para pacientes adultos utilizando sonda enteral. Metodo: se trata de estudio descriptivo que llevo a cabo una revision de la literatura sobre el tema para construir el instrumento y una posterior validacion por expertos. Participaron en la fase de validacion 15 expertos y los datos fueron recogidos entre junio y septiembre de 2012, mediante un formulario que contiene los datos relativos a los expertos y los datos evaluativos del protocolo. Resultados: el protocolo final resulto en dos secciones con seis temas en la primera y seis en la segunda. Tras su construccion, se llevo a cabo la validacion de la apariencia y del contenido, en el que alcanzo un indice de concordancia 0.837, considerado como teniendo alta confiabilidad. Conclusion: el protocolo es valido y aplicable en la practica, capaz de subsidiar disenos de intervencion y elegir la mejor forma de actuacion de la enfermeria.
Cutting an Organic Surface

Mapping a given surface onto a piece of the plane is an usual problem, and conformal mappings with border free approaches are classical as non-distorting methods. However, algorithms of this category are only able to produce a mapping from a surface topo-logically equivalent to a disc. In the general case, a topological cutting is thus required. The approach we are reporting here is a method that does not only take into account the topologi-cal properties by cutting the original surface into a disc [3], but also the the geometrical properties by globally selecting the local extrema of original arm-like surfaces (denoted organic surfaces in the following).
PREPROCESSING AND REAL TIME VISUALIZATION OF CT AND MRI DATA

The visualization of CT and MRI data has become a large part of scientific computer graphics during the last twenty years. These growing technologies are essential to gain insight to enormous amounts of information, to get better diagnosis. During the last years several different visualization approaches have been developed. In this paper we summarize the benefits and drawbacks of widely used methods, surface rendering and various types of volume rendering. Our aim is to determinate which method is the most effective in different type of situations.
Gestational diabetes mellitus – prevalence in southern Sweden and risk factors for subsequent diabetes

Background: Gestational diabetes mellitus (GDM) is associated with risks during pregnancy, during delivery, and in later life with a substantial risk of subsequent diabetes. The worldwide prevalence of GDM is increasing, but varies with differences in diagnostic methods and population characteristics. Results: Capillary glucose concentrations were found to be higher than venous glucose concentrations during oral glucose tolerance test (OGTT) after pregnancy (n = 55). Equivalence values for capillary glucose concentrations tended to be higher than those proposed by the WHO, but diagnostic disagreements mainly occurred close to the diagnostic cut-off limits. In southern Sweden, defining GDM as a 2-h capillary plasma glucose concentration of ≥ 10.0 mmol/L during a universal 75-g OGTT, there was a 35% increase in GDM prevalence (p < 0.001) from 2003 (1.9%) to 2012 (2.6%) when assessed in a log-linear Poisson model during a period with stable diagnostic procedures. 1–2 years after pregnancy with GDM (n = 456), the increased frequency of diabetes in non-European women (17% vs. 4% in European women, p < 0.001) was associated with increased insulin resistance―related to higher body mass index (BMI) in Arab women, and higher insulin resistance relative to BMI in Asian women. In logistic regression analysis, diabetes 5 years after GDM was associated with higher BMI at follow-up, non-European ethnicity, and higher OGTT 2-h glucose concentration in pregnancy (p < 0.0001). A prediction model based on these variables resulting in 86% correct classifications (n = 200), with an area under the receiver-operating characteristic curve of 0.91 (95% CI 0.86–0.95), was used in a function-sheet line diagram illustrating the individual effect of weight on diabetes risk. Conclusions: Interconversion of results from capillary sampling and venous sampling is associated with uncertainty, but it may be suitable when translating results on a group basis. The prevalence of GDM in southern Sweden was 2.6% in 2012, with an upward trend. In women with GDM, insulin resistance was associated with subsequent diabetes, predicted by BMI, non-European ethnicity, and glucose tolerance during pregnancy.
Clinical Decisions In Glaucoma

This text provides a practical and expert problem-solving approach to the diagnosis and management of the glaucoma patient. The authors place emphasis on an approach to chronic, year-in, year-out care of the glaucoma patient - one of the most challenging management issues of the general ophthalmologists' practice. The first section of the book reviews the differential diagnosis of the patients who present with signs and symptoms suggestive of glaucoma, such as elevated pressure, abnormal optic nerve head, abnormal visual field and abnormal anterior chamber angle. The second section focuses on the chronic management of glaucoma. The authors describe the thought process/clinical decisions used to formulate and monitor treatment. In particular, they describe: how to determine the vigour with which to treat and monitor the individual patient; and how to determine if treatment is adequate and/or successful.
Le nettoyage de la pierre

Due to the expansion of stone cleaning on buildings, decorative sculptures and statues and keeping in mind some drastic cleanings performed with very rough techniques during the 70s, cleaning methods have been rapidly improved within the last decade. Various and effective methods are now available. This evolution has also concerned the evaluating methods which now provide useful criteria to assess the cleaning results and to select the most appropriate method. Nowadays, a skilled operator using a suitable method is able to preserve patina which were previously removed. These patina are of different types and analytical investigations are necessary to determine their nature and origin. The question of their preservation points up certain scientific, aesthetic and doctrinal considerations. This technical document which deals with stone cleaning is divided into 5 parts detailing these different points.
Software-defined datacenter network debugging

Software-defined Networking (SDN) enables flexible network management, but as networks evolve to a large number of end-points with diverse network policies, higher speed, and higher utilization, abstraction of networks by SDN makes monitoring and debugging network problems increasingly harder and challenging. While some problems impact packet processing in the data plane (e.g., congestion), some cause policy deployment failures (e.g., hardware bugs); both create inconsistency between operator intent and actual network behavior. Existing debugging tools are not sufficient to accurately detect, localize, and understand the root cause of problems observed in a large-scale networks; either they lack in-network resources (compute, memory, or/and network bandwidth) or take long time for debugging network problems. This thesis presents three debugging tools: PathDump, SwitchPointer, and Scout, and a technique for tracing packet trajectories called CherryPick. We call for a different approach to network monitoring and debugging: in contrast to implementing debugging functionality entirely in-network, we should carefully partition the debugging tasks between end-hosts and network elements. Towards this direction, we present CherryPick, PathDump, and SwitchPointer. The core of CherryPick is to cherry-pick the links that are key to representing an end-to-end path of a packet, and to embed picked linkIDs into its header on its way to destination. PathDump is an end-host based network debugger based on tracing packet trajectories, and exploits resources at the end-hosts to implement various monitoring and debugging functionalities. PathDump currently runs over a real network comprising only of commodity hardware, and yet, can support surprisingly a large class of network debugging problems with minimal in-network functionality. The key contributions of SwitchPointer is to efficiently provide network visibility to end-host based network debuggers like PathDump by using switch memory as a "directory service" — each switch, rather than storing telemetry data necessary for debugging functionalities, stores pointers to end hosts where relevant telemetry data is stored. The key design choice of thinking about memory as a directory service allows to solve performance problems that were hard or infeasible with existing designs. Finally, we present and solve a network policy fault localization problem that arises in operating policy management frameworks for a production network. We develop Scout, a fully-automated system that localizes faults in a large scale policy deployment and further pin-points the physical-level failures which are most likely cause for observed faults.
Pathobiology of saphenous vein grafts

The long saphenous vein graft is the commonest conduit used for coronary artery bypass surgery. The short and long term success of the procedure depends on the patency of these bypass grafts. Vein graft disease can be divided into early (in the first 30 days), intermediate (1 month to 1 year) and late (over 1 year). Early graft failure is usually caused by graft thrombosis and may be related to the surgical procedure, intermediate graft disease results from intimal hyperplasia while late graft pathology is a consequence of atherosclerosis. The etiology and pathological processes leading to these damaging effects on saphenous vein grafts are tackled in this review. The loss of endothelial integrity, the phenotypic changes in vascular smooth muscle cells and involvement of adventitial cells with collaboration of blood borne factors lead to occlusive pathology of saphenous vein grafts. The accelerated intimal hyperplasia and atherosclerosis are characteristic pathobiological features of these vein grafts. Inflammatory and immunological changes and graft thrombosis are mediated through the secretion and up regulation of growth factors, pro coagulant substances and other proteins arising from the vein wall cells and the blood flowing through them.
Improving statistical machine translation of informal language: a rule-based pre-editing approach for French Forums

La barriere linguistique limite le partage de connaissances entre communautes sur les forums internet. La traduction automatique (TA), qui permettrait d’aborder cette limitation, rencontre de nombreuses difficultes avec les textes communautaires. Cette these vise a investiguer dans quelle mesure un processus de preedition automatique ou interactif utilisant une technologie a base de regles peut reduire ces difficultes et ainsi ameliorer la TA statistique de textes de forums francais. Nous etudions differentes transformations puis evaluons leur impact sur la TA. Au-dela d’une amelioration significative de la qualite de la TA, nous observons une reduction de l’effort technique et temporel de post-edition. Au travers d’une etude de faisabilite avec de vrais utilisateurs de forums, nous observons que la tâche de preedition est envisageable dans ce contexte. Finalement, nous confirmons la portabilite du processus de preedition developpe dans ce travail vers d’autres systemes de TA et pour des forums de differents domaines.
A PROPOSED NEURO -FUZZY MODEL FOR ADULT ASTHMA DISEASE DIAGNOSIS

The task of medical diagnosis with the help different intelligent system techniques is always crucial because it require high level of accuracy and less time consumption in decision making. Among all other AI techniques Artificial Neural Networks (ANN) as a tool for medical diagnosis has become the most popular in last few decades due to its flexibility and accuracy. ANN was developed after getting the inspiration from biological neurons. There are various diseases that are still needed to be diagnosed. Among many other critical diseases like cancer, thyroid disorder, diabetes, heart diseases, neuro diseases, asthma disease was also tried to bediagnosed effectively with various ANN mechanisms by different researchers. Due to various uncertainties about symptoms the study of Neuro-Fuzzy technique in this context became very popular in last few years. Neuro-Fuzzy now-a-days is one of the most advanced technique that is mainly concatenation of two model-neural networks and the fuzzy logic. In this model various parameters are used that are much crucial if ill-chosen and may led to failure of the whole system. Recent trend in analysis is following this model for advanced expert work. In this study an enhanced Neuro-fuzzy model has been proposed for the proper diagnosis of adult Asthma disease and to foster the proper aid or medication to the patients and make physicians alert for the upcoming disease pattern otherwise they may lack in the process of providing improper medication at right time. In the first phase data collected from various hospitals are used to train by three different types of learning of ANN like ANN with Self Organizing Maps (SOM), ANN with Learning Vector Quantization (LVQ) and ANN with Backpropagation Algorithm (BPA) through NF tool for much accurate result. In the second phase fuzzy rule base is applied to the classified data for the diagnosis of the disease.
Cities and Cinema

Section 1 1. Modernity and the City Film: Berlin 2. The Dark City: Film Noir - Los Angeles 3. The City of Love: Paris Section 2 4. City Film Industry: Hong Kong 5. The Divided City and the City in Ruins: Belfast, Beirut, and Berlin 6. Utopia and Dystopia: Fantastic and Virtual Cities Section 3 7. Ghettos and Barrios 8. The City as Queer Playground 9. The Global City and Cities in Globalization. Conclusion: From the Train Effect to the Favela Effect: How to do Further Research. Filmography. Bibliography
Phase I/II Study of the P-Glycoprotein (Pgp) Inhibitor Zosuquidar Administered by Continuous Infusion (CIV) with Daunorubicin (DNR) and Cytarabine (ARA-C) as Primary Therapy in Older Patients with Pgp-Positive Acute Myeloid Leukemia (AML).

Background: Pgp expression in AML increases with age and correlates with inferior therapeutic response and survival. Zosuquidar is a potent and highly specific Pgp inhibitor with minimal pharmacokinetic (PK) interaction with conventional xenobiotic antineoplastics. Prolonged Pgp blockade is believed necessary to optimize antineoplastic sensitization in resistant cells in vitro . We previously reported that 72-hour CIV Zosuquidar at 700 mg/d resulted in rapid and sustained Pgp inhibition during the entire period of anthracycline administration in Pgp+ AML (Lancet, et al. ASH 2006). Methods: We report interim results from a Phase I/II trial of 72-hr CIV zosuquidar in older adults with newly diagnosed Pgp+ AML. Primary objective: to determine the response (CR + CRp) rate in Pgp+ patients. Eligibility included ages 55–75, ECOG PS 0-2, adequate end-organ function, and Pgp+ by functional assay. Zosuquidar was initiated 4 hrs prior to the first doses of DNR (45 mg/m 2 /d x 3d) and ARA-C (100 mg/m 2 /d CIV x 7d) and continued for 72 hrs. Reinduction with the same dosing schedule was permitted in patients with significant cytoreduction without aplasia. Patients who achieved a CR/CRp received up to 2 cycles of consolidation with the same agents using an abbreviated schedule. Results: 67 patients with Pgp+ AML were enrolled on the study; 80 patients were included in the safety analysis. Sixty-two of the 67 Pgp+ patients received Zosuquidar at 700 mg/day, while 5 received 800 mg/day (during phase I). Median age was 66; M/F was 46/21; cytogenetics: adverse (19), intermediate (29), and unknown/not done (19); de novo /secondary AML: 36/31. Mean percentage of planned Zosuquidar actually administered was 94%. CR/CRp was achieved in 32 of 66 (48%) evaluable Pgp+ patients (CR=25, CRp=7). Fifteen of 31 (48%) patients with secondary AML, and 6 of 19 (32%) with adverse-risk cytogenetics achieved CR/CRp. Eight of 14 (57%) patients age ≥ 70 responded. Induction-related death ( Conclusions: CIV Zosuquidar 700 mg/d with DNR and ARA-C is well tolerated, with signs of clinical benefit in poor-risk older patients with Pgp+ AML, warranting continued study of this combination. Accrual to the current trial is ongoing.
Signposting the inferencing route : a relevance theoretic analysis of intertextuality and metaphors in print advertisements

This article reports an analysis of the manner in which copywriters use direct and indirect product claims to guide consumers' interpretations of metaphors in print advertisements. The analysis utilises a relevance theoretic framework, and the results are illustrated by means of a qualitative analysis of four case studies, taken from a larger sample of 120 print advertisements. The first stage of the analysis employs the concept 'intertextuality' to study the manner in which advertising texts construct the intertext as the source of a metaphor, with the advertised product as the target. In the second stage, a relevance theoretic framework is used to investigate the role that direct and indirect claims play in guiding consumers' interpretations of the product claims inherent in these metaphors. To achieve the latter aim, Simpson's (2001) 'reason' and 'tickle' constructs are used. Aanwysings langs die inferensieroete : 'n relevansie-teoretiese analise van intertekstualiteit en metafore in gedrukte advertensies Die artikel doen verslag oor 'n ontleding van die wyse waarop kopieskrywers gebruik maak van direkte en indirekte produkaansprake om verbruikers se interpretasies van metafore in gedrukte advertensies te lei. Die analise maak gebruik van 'n relevansie teoretiese raamwerk, en die resultate word geillustreer deur middel van 'n kwalitatiewe ontleding van vier gevallestudies, geneem uit 'n groter steekproef van 120 gedrukte advertensies. Die eerste fase van die analise maak gebruik van die begrip 'intertekstualiteit', ten einde 'n studie te maak van die wyse waarop die interteks opgestel geword as die bron van die metafoor, met die geadverteerde produk as die teiken. Tydens die tweede fase, word 'n relevansie teoretiese raamwerk gebruik om te ontleed watter rol direkte en indirekte aansprake speel in die begeleiding van verbruikers se interpretasies van sulke metafore. Om hierdie doel te bereik, word Simpson (2001) se 'rede' en 'prikkel' konstrukte gebruik.
The treatment of cutaneous malignancies with topically applied cycloheximide

Results obtained from an animal test system for epidermal cytotoxic drugs prompted the topical use of 1% cycloheximide in the treatment of histologically confirmed superficial basal cell carcinomata of the skin. Excellent clinical clearing of lesions has been demonstrated and this has been confirmed by post treatment biopsies. Preliminary findings in solar keratoses and intraepidermal carcinomata of the skin are also reported.
Mesenchymal-epithelial transition regulates initiation of pluripotency exit before gastrulation

ABSTRACT The pluripotent epiblast gives rise to all tissues and organs in the adult body. Its differentiation starts at gastrulation, when the epiblast generates mesoderm and endoderm germ layers through epithelial-mesenchymal transition (EMT). Although gastrulation EMT coincides with loss of epiblast pluripotency, pluripotent cells in development and in vitro can adopt either mesenchymal or epithelial morphology. The relationship between epiblast cellular morphology and its pluripotency is not well understood. Here, using chicken epiblast and mammalian pluripotency stem cell (PSC) models, we show that PSCs undergo a mesenchymal-epithelial transition (MET) prior to EMT-associated pluripotency loss. Epiblast MET and its subsequent EMT are two distinct processes. The former, a partial MET, is associated with reversible initiation of pluripotency exit, whereas the latter, a full EMT, is associated with complete and irreversible pluripotency loss. We provide evidence that integrin-mediated cell-matrix interaction is a key player in pluripotency exit regulation. We propose that epiblast partial MET is an evolutionarily conserved process among all amniotic vertebrates and that epiblast pluripotency is restricted to an intermediate cellular state residing between the fully mesenchymal and fully epithelial states. Highlighted Article: Amniote epiblast reaches full epithelialization status before gastrulation. A partial mesenchymal-to-epithelial transition process regulates its pluripotency exit.
Continuous Visible Query for Three-Dimensional Objects in Spatial Databases

Present research of visible query focuses on points and segments in two-dimensional space, while disfigurements occur during processing of visible query in three-dimensional space. In this paper, Continuous Visible Range Query Based on Control Point (CVRQ-CP) is proposed to solve the visible query in a 3D spatial database. Firstly, the horizontal angle (HA) and Vertical Projection Angle (VPA) for 3D objects in a spatial database were used in the visibility testing method. The HA and VPA in the processing of the continuous visible query created visibility changes, defining and confirming the control point. Finally, the algorithm of Continuous Visible Range Query Based on Control Point (CVRQ-CP) was proposed. Verified by experiments, the CVRQ-CP algorithm correctly deals with the visible query of 3D spatial objects. The CVRQ-CP algorithm has better superior accuracy over present visible queries in 3D spatial databases.