Miracle-dz/UniFAR-FTUs huggingface dataset:
[Clinical observation on prevention of "jia wei si jun zi tang" from damage of hepatic reserving function after intervention of liver cancer].

OBJECTIVE To observe prevention of "Jia Wei Si Jun Zi Tang" (JWSJZT) from damage of hepatic reserving function after intervention of liver cancer. METHODS 65 patients with advance stage of liver cancer were randomly into two groups, the control group (regular protective therapy) and the treatment group (regular protective therapy + JWSJZT). There were 33 and 32 cases in the control group and treatment group,respectively. ICGR15 was detected before the first and the second intervention treatment and one month after the second intervention treatment, respectively. ICGR15 change was observed before and after the intervention treatment in the two groups. RESULTS ICGR15 was 11.13% +/- 7.28% in the treatment group and 11.81% +/- 7.43% in the control group (P > 0.05) before the first intervention; 18.36% +/- 9.82% in the control group and 12.18% +/- 5.22% in the treatment group, before the second invention treatment (P < 0.05); 19.12% +/- 9.96% in the control group and 12.83% +/- 5.28% in the treatment group one month after the second intervention treatment (P < 0.05). CONCLUSION The western medicine + JWSJZT group is superior in curative effect to western medicine group.
Laser Dopplers to Determine Cutaneous Blood Flow

BACKGROUND Laser Dopplers can be useful in determining the relative amount of blood flowing through superficial skin. These instruments may be useful in assessing blood flow in healing wounds, flaps, and grafts. OBJECTIVE To review the theory and types of laser Dopplers available. METHODS This work includes a review of the literature. RESULTS Laser Dopplers potentially have a broad range of applications in dermatologic surgery and dermatology. Because laser Dopplers can quantify blood flow, the course of wound healing over time can be studied; however, for predicting viability of skin flaps and grafts, laser Dopplers have not been able to supplant clinical assessment. CONCLUSION Laser Dopplers provide an additional means of assessing superficial blood flow in the skin. This blood flow, which can be quantified, may be useful in studying wound and flap and graft healing.
The Spitzer c2d Survey of Large, Nearby, Interstellar Clouds. III. Perseus Observed with IRAC

We present observations of 3.86 deg2 of the Perseus molecular cloud complex with the Spitzer Space Telescope Infrared Array Camera (IRAC). The maps show strong extended emission arising from shocked H2 in outflows and from polycyclic aromatic hydrocarbon features. More than 120,000 sources are extracted toward the cloud. Based on their IRAC colors and comparison to off-cloud and extragalactic fields, we identify 400 candidate young stellar objects. About two-thirds of these are associated with the young clusters IC 348 and NGC 1333, while the last third is distributed over the remaining cloud. The young stellar objects are classified according to the slope of their spectral energy distributions. Significant differences are found between the numbers of embedded Class I objects and more evolved Class II objects in IC 348, NGC 1333 and the remaining cloud, with the embedded Class I and "flat-spectrum" YSOs constituting 14%, 36% and 47% of the total number of YSOs identified in each of these regions. The high number of Class I objects in the extended cloud (61% of the Class I objects in the entire cloud) suggests that a significant fraction of the current star formation occurs outside the two main clusters. Finally, we discuss a number of outflows and identify their driving sources, including the deeply embedded Class 0 sources outside the two main clusters. The Class 0 objects are detected by Spitzer and have very red [3.6] - [4.5] colors, but they do not show similarly red [5.8] - [8.0] colors. The Class 0 objects are easily identifiable in color-color diagrams but are problematic to extract automatically due to the extended emission from shocked gas or scattered light in cavities related to the associated outflows.
Recent advances in the therapy of renal cancer

Metastatic clear cell renal cell cancer has traditionally been treated with cytokines (interferon or interleukin-2). Improved understanding of biology has engendered novel targeted therapeutic agents that have radically altered the outlook. Vascular endothelial growth factor, the related receptor and the mTOR signal transduction pathway have particularly been exploited. Sunitinib malate, sorafenib and temsirolimus have improved clinical outcomes compared with interferon in randomized trials. Other multitargeted tyrosine kinase inhibitors (lapatinib, axatinib and pazopanib) and antiangiogenic agents (bevacizumab and lenalidomide) have also demonstrated activity in early studies. Combinations of these agents are being evaluated. The future of the therapy of renal cancer appears promising owing to the efficacy of these novel agents. Clinical trials designed to further assess these and other agents need to be vigorously supported.
Abnormal fronto‐parietal coupling of brain rhythms in mild Alzheimer's disease: a multicentric EEG study

Cholinergic deafferentation/recovery in rats mainly impinges on the fronto‐parietal coupling of brain rhythms [D. P. Holschneider et al. (1999) Exp. Brain Res., 126, 270–280]. Is this reflected by the functional coupling of fronto‐parietal cortical rhythms at an early stage of Alzheimer's disease (mild AD)? Resting electroencephalographic (EEG) rhythms were studied in 82 patients with mild AD and in control subjects, such as 41 normal elderly (Nold) subjects and 25 patients with vascular dementia (VaD). Patients with AD and VaD had similar mini‐mental state evaluation scores of 17–24. The functional coupling was estimated by means of the synchronization likelihood (SL) of the EEG data at electrode pairs, accounting for linear and non‐linear components of that coupling. Cortical rhythms of interest were delta (2–4 Hz), theta (4–8 Hz), alpha (1 8–10.5 Hz), alpha 2 (10.5–13 Hz), beta 1 (13–20 Hz), beta 2 (20–30 Hz) and gamma (30–40 Hz). A preliminary data analysis (Nold) showed that surface Laplacian transformation of the EEG data reduced the values of SL, possibly because of the reduction of influences due to head volume conduction. Therefore, the final analysis was performed on Laplacian‐transformed EEG data. The SL was dominant at alpha 1 band in all groups. Compared with the Nold subjects, patients with VaD and mild AD presented a marked reduction of SL at both fronto‐parietal (delta–alpha) and inter‐hemispherical (delta–beta) electrode pairs. The feature distinguishing the patients with mild AD with respect to patients with VaD groups was a more prominent reduction of fronto‐parietal alpha 1 SL. These results suggest that mild AD is characterized by an abnormal fronto‐parietal coupling of the dominant human cortical rhythm at 8–10.5 Hz.
Determination of renal stone composition with dual-energy CT: in vivo analysis and comparison with x-ray diffraction.

PURPOSE To preoperatively assess the composition of urinary stones by using dual-energy computed tomography (CT), with postoperative in vitro x-ray diffraction analysis as the reference standard. MATERIALS AND METHODS Institutional review board approval was obtained, and all participants provided written informed consent. Twenty-seven patients aged 50-64 years with renal stones, who were scheduled for stone extraction with percutaneous nephrolithotomy (PCNL), preoperatively underwent nonenhanced single-source dual-energy multidetector CT with 2-mm section thickness, 1-mm increments, 140 kVp, and 250 mAs. Regions of interest were drawn on low- and high-energy images, and low- and high-energy attenuation ratios were calculated for each stone scanned in vivo. The attenuation ratios for the patients were compared with those for an in vitro stone library phantom model of 37 stones with known chemical compositions. After surgery, the extracted stones were analyzed by using x-ray diffraction. The results of in vivo multidetector CT and ex vivo chemical analysis were compared. RESULTS Dual-energy low- and high-energy attenuation ratios measured with the phantom were less than 1.1 for uric acid, 1.1-1.24 for cystine, and greater than 1.24 for calcified stones. Struvite stones had attenuation ratios that overlapped with calcified stone ratios and thus could not be assessed reliably. Four patients had mixed stones (<75% of a single component), and one patient had a struvite stone. Of 27 patients, 22 (82%) (exact confidence interval [CI]: 68%, 92%) received a correct diagnosis with dual-energy CT: all six (100%; exact CI: 54%, 100%) patients with uric acid stones, 15 (79%; exact CI: 62%, 95%) of the 19 patients with calcium stones, and the one (100%) patient with a cystine stone. The patient with a struvite stone did not receive a correct dual-energy CT-based diagnosis. CONCLUSION Dual-energy multidetector CT may enable accurate in vivo characterization of kidney stone composition.
MIMO STBC Adaptive Array for Fast Fading Channel

We introduce a novel configuration for a multi-user Multiple-Input Multiple-Output (MIMO) system in mobile communication over fast fading channels using space-time block coding (STBC) and adaptive array. The proposed scheme adopts the simultaneous transmission of data and pilot signals which reduces control errors caused by delay of obtaining channel state information (CSI). Data and pilot signals are then encoded using a space-time block code and are transmitted from two transmit antennas. In order to overcome the fast fading problem, implementation of adaptive array using recursive least squares (RLS) algorithms is considered at the base station. Through computer simulation, it is shown that the proposed scheme in this way can overcome Doppler spread in higher frequencies and suppress co-channel interference up to N - 1 users for N receiving antennas.
Bloch Simulation Acceleration for Fast Pulse Design in Parallel Transmit

Introduction: Iterative calculation of parallel transmit (pTx) RF pulses based on the optimal control theory [1] is versatile but slow since it relies on a large number of Bloch simulations for cost function and gradient calculations. Recent work by Grissom et al [2] focused on reducing the design time by linear approximation of the Bloch equations around a particular solution. Here we propose analytical and computational methods to improve the speed of the Bloch simulation itself. In the first method, we formulate the optimal control theory in a “local rotating frame” which transforms away all longitudinal magnetic fields present in the system and thereby simplifies the numerical workflow. In the second method, we reduce the arithmetic calculation time by shifting the calculation load from the conventional Central Processing Unit (CPU) to a Graphics Processing Unit (GPU) [3]. Both methods provide significant gain in optimization speed with negligible impact on the end result.
Dual-Polarized Filtering Antenna With High Selectivity and Low Cross Polarization

This paper presents a dual-polarized patch antenna with quasi-elliptic bandpass responses. The proposed antenna is mainly composed of a feeding network, a driven patch, and a stacked patch, with its entire height being 0. 09λ. The feeding network consists of two orthogonal H-shaped lines that coupled to the driven patch, each for one polarization. The elaborately designed feeding lines not only ensure a sharp roll-off rate at the lower band edge, but also help to achieve low cross polarization and high isolation between two feeding ports. On the other hand, the upper stacked patch provides improved suppression levels at the upper stopband and also an enhanced gain within passband. Consequently, a compact dual-polarized antenna with satisfying filtering performance is obtained, without using extra filtering circuits. For demonstration, an antenna is designed to fit the specification of LTE band (2.49-2.69 GHz). The implemented antenna achieves an average a gain of 9 dBi, a cross-polarization ratio of 29 dB, an isolation of 35 dB within LTE band. The out-of-band suppression level is more than 40 dB within the 2G and 3G frequency bands from 1.71-2.17 GHz. It can be used as the antenna elements in multiband base station antenna arrays to reduce the mutual coupling.
Loss of Plastoglobule Kinases ABC1K1 and ABC1K3 Causes Conditional Degreening, Modified Prenyl-Lipids, and Recruitment of the Jasmonic Acid Pathway[W]

ABC1K1 and ABC1K3, two of the six plastoglobule ABC1K kinases, physically interact, and the double mutant displays a conditional senescent-like phenotype. ABC1K1 and 3 regulate prenyl-lipid metabolism and phosphorylation targets likely include tocopherol cyclase, VTE1. Plastoglobules function as specialized thylakoid microdomains with local enrichment of selected proteins and metabolites. Plastoglobules (PGs) are plastid lipid-protein particles. This study examines the function of PG-localized kinases ABC1K1 and ABC1K3 in Arabidopsis thaliana. Several lines of evidence suggested that ABC1K1 and ABC1K3 form a protein complex. Null mutants for both genes (abc1k1 and abc1k3) and the double mutant (k1 k3) displayed rapid chlorosis upon high light stress. Also, k1 k3 showed a slower, but irreversible, senescence-like phenotype during moderate light stress that was phenocopied by drought and nitrogen limitation, but not cold stress. This senescence-like phenotype involved degradation of the photosystem II core and upregulation of chlorophyll degradation. The senescence-like phenotype was independent of the EXECUTER pathway that mediates genetically controlled cell death from the chloroplast and correlated with increased levels of the singlet oxygen–derived carotenoid β-cyclocitral, a retrograde plastid signal. Total PG volume increased during light stress in wild type and k1 k3 plants, but with different size distributions. Isolated PGs from k1 k3 showed a modified prenyl-lipid composition, suggesting reduced activity of PG-localized tocopherol cyclase (VTE1), and was consistent with loss of carotenoid cleavage dioxygenase 4. Plastid jasmonate biosynthesis enzymes were recruited to the k1 k3 PGs but not wild-type PGs, while pheophytinase, which is involved in chlorophyll degradation, was induced in k1 k3 and not wild-type plants and was localized to PGs. Thus, the ABC1K1/3 complex contributes to PG function in prenyl-lipid metabolism, stress response, and thylakoid remodeling.
Prediction of digestible and metabolisable energy in soybean meals produced from soybeans of different origins fed to growing pigs

The objective of this experiment was to determine the digestible energy (DE) and metabolisable energy (ME) in 22 sources of soybean meal (SBM) produced from soybeans from different countries and subsequently to establish equations for predicting the DE and ME in SBM based on their chemical composition. The 22 sources of SBM were all processed in Chinese crushing plants, but the soybeans used originated from China (n = 6), the US (n = 6), Brazil (n = 7) or Argentina (n = 3). The basal diet was a corn-based diet and 22 additional diets were formulated by mixing corn and 24.3% of each source of SBM. The average DE and ME in SBM from China, the US, Brazil and Argentina were 15.73, 15.93, 15.64 and 15.90 MJ/kg and 15.10, 15.31, 14.97 and 15.42 MJ/kg, respectively, and no differences among countries were observed. From a stepwise regression analysis, a series of DE and ME prediction equations were generated. The best-fit equations for SBM were DE = 38.44–0.43 crude fibre −0.98 gross energy +0.11 acid detergent fibre (R2 = 0.67, p < 0.01) and ME = 2.74 + 0.97 DE −0.06 crude protein (R2 = 0.79, p < 0.01). In conclusion, there were no differences in the DE and ME of SBM among the different soybean sources used in this experiment. The DE and ME of SBM of different origin can be predicted based on their chemical composition when fed to growing pigs.
A universal variable on-time compensation to improve THD of high-frequency CRM boost PFC converter

The critical conduction mode Boost PFC converter utilizes the resonance to achieve soft-switching, however, leading to high THD and poor power quality, especially at high switching frequency applications. This paper presents a systematic operation analysis of the CRM Boost PFC converter considering the parasitic parameters and investigates the negative influence of resonance process to THD. In order to improve input current THD, a variable on-time control method is proposed to keep the average inductor current following the intended sinusoidal input current. The proposed implementation combines the advantages of digital control and analog control, effectively decreasing the total cost of the system. And the proposed variable on-time compensation method is verified with the experimental results well.
Tooth pulp- and facial hair mechanoreceptor-evoked responses of trigeminal sensory neurons are attenuated during ketamine anesthesia.

BACKGROUND Evidence exists that ketamine, administered systemically using a dose required for inducing a state of anesthesia, may antagonize nociceptive but not innocuous input to lumbar dorsal horn neurons. However, it is unclear whether ketamine exerts this selective action on sensory inputs to trigeminal sensory neurons. The current study was undertaken to compare the responses evoked in trigeminal sensory neurons by electrical stimuli applied to the tooth pulp versus air-puff stimuli applied to facial hair mechanoreceptors (FHMs) during quiet wakefulness versus ketamine anesthesia. METHODS Accordingly, responses of rostral trigeminal sensory nuclear complex (TSNC) and trigeminothalamic tract neurons evoked by tooth pulp (a source of small-diameter fiber input) and FHMs (a source of larger-diameter fiber input) were recorded extracellularly from chronically instrumented cats before, during, and after recovery from the anesthetic state induced by a single (2.2 mg/kg) intravenous injection of ketamine. RESULTS Overall, tooth pulp-evoked responses of TSNC neurons were maximally suppressed by 50% within 5 min after the intravenous administration of ketamine. Ketamine also suppressed the FHM-evoked responses of TSNC and trigeminothalamic neurons by 45%. The time course of ketamine's suppressive action was equivalent for tooth pulp- and FHM-evoked responses. However, the recovery of tooth pulp-evoked TSNC neuronal responses at suprathreshold intensities was markedly prolonged compared with neuronal responses driven by threshold stimuli or FHM. CONCLUSIONS These electrophysiologic results in the chronically instrumented cat preparation indicate that a nonselective suppression of orofacial somatosensory information occurs during ketamine anesthesia. The prolonged recovery of suprathreshold responses of TSNC neurons mediated by small-diameter afferent fiber input may partly underlie the analgesic action of ketamine that is clinically relevant at subanesthetic doses.
artery disease . with left anterior descending ischaemic myocardium in patients scintigraphy to assess extent of Use of exercise thallium

In this study we attempted to examine the extent of jeopardised myocardium in patients with severe left anterior descending disease. The jeopardised myocardium was defined by the number of perfusion defects in the distribution of the left anterior descending artery depicted on exercise thallium201 images. One segment in each of the three projections was considered to represent the distribution of this vessel, that is the anterolateral segments in the anterior projection, the anteroseptal segment in the left anterior oblique projection, and the anterior segment in the lateral projection. We selected 45 patients with > 70 per cent diameter narrowing of the left anterior descending artery and abnormal exercise images in the distribution of this vessel. There were 17 patients with isolated left anterior descending artery disease and 28 patients with multivessel disease including the left anterior descending artery. Fifteen patients (33%) had one perfusion defect (four patients with isolated disease and 11 patients with multivessel disease); 17 patients (38%) had two perfusion defects (six with isolated disease and 11 with multivessel disease); and 13 patients (29%) had three perfusion defects (seven with isolated disease and six with multivessel disease). The anteroseptal segment was the most common segment to become ischaen.ic during exercise and was abnormal in 40 of the 45 patients (89%). The anterior segment in 27 patients (60%) was next, and the anterolateral segment in 20 patients (44%) the least common. The number of defects did not correlate with the site of disease of the left anterior descending artery (proximal vs. distal to the first septal and first diagonal branches); the degree of left anterior descending narrowing (70 to 99% vs. total occlusion); collaterals; left ventricular asynergy; the presence of isolated left anterior descending disease in contrast with multivessel disease. We conclude that variations in the extent ofperfusion abnormalities seen in patients with disease of the left anterior descending artery suggest that these patients do not constitute a homogeneous group. Future studies designed to study the effect of medical or surgical treatment in such patients may be more meaningful if the extent of jeopardised myocardium, as defined by exercise thallium-201 imaging, is incorporated as a variable in group comparison. Our results also suggest that the number of perfusion defects do not predict the site of the lesion of the left anterior descending artery in relation to its first septal and diagonal branches.
A framework to analyze different intellectual property systems

With many intellectual property protection (IPP) strategies to choose from, firms can protect their intellectual property by using different intellectual property protection systems (IPS), including macro-level IPS, micro-level IPS and meso-level IPS. In order to study the differences of these systems, we construct a framework based on governance theory, the framework containing three dimensions: (1) institutional design of IPS; (2) implementation of institution; (3) long-term survival and continuation of IPP institution. Then we conduct a case study to figure out cluster IPP mode in a cluster of Zhejiang to illustrate our framework at meso-level.
Insidious atrophy of retinal nerve fibers in multiple sclerosis. Funduscopic identification in patients with and without visual complaints.

Slit-like defects in the peripapillary nerve fiber layer and corollary defects in the field of vision occur frequently in multiple sclerosis, often before there is a change in the patient's visual acuity, color perception, or optic disc. These subtle ophthalmoscopic signs indicate scattered attrition of axon bundles by lesions in the anterior visual pathway. The appearances of such defects in the retinal nerve fiber layer are described and exemplified photographically in case reports of two young adults, one with symptoms of spinal cord disease and the other with a brain stem syndrome.