Miracle-dz/UniFAR-FTUs huggingface dataset:
Is Conservative Surgical Treatment Sufficient to Treat Unicystic Mural Ameloblastoma in Infant?

AbstractAmeloblastoma, a benign neoplasm derived from odontogenic epithelium, is an aggressive and locally invasive tumor. It represents 11% of all odontogenic tumors and 1% of all oral odontogenic epithelial tumors. In this case report, a 20-month-old boy was referred to our clinic with complaint of collapse in his symphysis region of the mandible. Radiographic examination revealed unilocular radiolucency in this region. The lesion was enucleated with 1 tooth germ under general anesthesia and diagnosed as mural unicystic ameloblastoma by histopathologic examination. After the surgery, complete healing was obtained clinically and radiographically. No sign of recurrence has been seen during the follow-up period of 4.5 years. To our knowledge, this was the second youngest case of ameloblastoma in the English literature. However, it is the youngest case of ameloblastoma that occurred in an infant boy.
Economic analysis of targeting chemotherapy using a 21-gene RT-PCR assay in lymph-node-negative, estrogen-receptor-positive, early-stage breast cancer.

OBJECTIVE To appraise the economics of a recurrence score (RS), based on an assay that predicts distant recurrence-free survival in lymph-node-negative (LN-), estrogen-receptor-positive (ER+) patients with early-stage breast cancer receiving tamoxifen. STUDY DESIGN Cost-utility analyses using a decision analytic model. METHODS Using a Markov model, we forecast overall survival, costs, and cost effectiveness of using the RS in patients classified as having low or high risk of distant recurrence based on National Comprehensive Cancer Network (NCCN) clinical guidelines. Data from a large multicenter clinical trial (NSABP B-14) were analyzed to derive risk classification based on guideline criteria and RS assignments. Efficacy of adjuvant chemotherapy (CT) on distant recurrence-free survival (DRFS) was based on published meta-analyses of CT trials. The analysis took a societal perspective, considering survival, quality of life, and relevant costs. RESULTS Fifty-three patients (8%) were classified as having low risk of distant recurrence by NCCN guidelines and the RS reclassified 15 of these patients (28%) to an intermediate/high-risk group. The remaining 615 patients (92%) were classified at high risk of distant recurrence by NCCN guidelines and the RS reclassified 300 of these patients (49%) to a low-risk group. Among a hypothetical cohort of 100 patients, RS is predicted on average to increase quality-adjusted survival by 8.6 years and reduce overall costs by $202 828. RS was cost saving in more than two-thirds of probabilistic simulations, with cost effectiveness most influenced by the propensity to administer CT based on RS results, and by the proportion of patients at low risk as defined by NCCN guidelines. CONCLUSIONS The RS predicts more accurately than current guidelines recurrence risk in LN-, ER+ patients with early-stage breast cancer. If applied appropriately, the assay is predicted to increase quality-adjusted survival and save costs.
Determining cholinesterase activity in human plasma. Simple test-strip method.

NUMEROUS titrametric, manometric, colorimetric, and electrometric methods of determining the activity of cholinesterase (ChE) have been reported.1Among these quantitative measurements, the electrometric method of Michel2and the colorimetric method of de la Huerga et al3are the most widely used. Simpler methods based upon the change of color of suitable indicators have been reported.4,5However, all of these require facilities which are not usually available in the average clinical laboratory. Limperos and Ranta6described a semiquantitative method of determining ChE in the whole blood by observing the color change of bromothymol blue. This was modified and adapted for use as a screening test.7, 8Herzfeld and Stumpf9reported on a test-paper method, the results of which were recently demonstrated by other investigators to be in reasonably good agreement with results obtained by the manometric and the electrometric methods.10, 11This ChE
Effects of Implicit Positive Ratings for Quality Assessment of Wikipedia Articles

In this paper, we propose a method to identify high-quality Wikipedia articles by using implicit positive ratings. One of the major approaches for assessing Wikipedia articles is a text survival ratio based approach. In this approach, when a text survives beyond multiple edits, the text is assessed as high quality. However, the problem is that many low quality articles are misjudged as high quality, because every editor does not always read the whole article. If there is a low quality text at the bottom of a long article, and the text has not seen by the other editors, then the text survives beyond many edits, and the text is assessed as high quality. To solve this problem, we use a section and a paragraph as a unit instead of a whole page. In our method, if an editor edits an article, the system considers that the editor gives positive ratings to the section or the paragraph that the editor edits. From experimental evaluation, we confirmed that the proposed method could improve the accuracy of quality values for articles.
Tissue Doppler Derived Longitudinal Strain and Strain Rate During the First 3 Days of Life in Healthy Term Neonates

Tissue Doppler derived longitudinal strain and strain rate were studied in 48 healthy term neonates by measuring peak systolic strain (PSS) and peak systolic strain rate (PSSR) in 18 heart segments on day 1–3 of life. The mean PSS for each examination was −21.8% (−22.1, −21.4) [mean (95%CI)], and the mean PSSR was −1.78/s (−1.81, −1.74). Age (d), fetal shunts, and heart rate had negligible impact on measurements for any segment. The fractional shortening had negligible impact on septum and left heart segments and the pulmonary artery pressure had no impact on the right heart segments. Values varied significantly between segments and individuals, and were lower (closer to zero) in images of low quality than in images of high quality (p < 0.05). Both apical and basal segments values were lower in the septum and higher in the right ventricle than in the left ventricle (p < 0.05), except for no difference between the basal left and right segments PSSR. Apical segments values were higher than basal segments values in the right ventricle (p < 0.05) but not in the septum or the left ventricle. At present, PSS and PSSR are more feasible for quantifying differences between segment groups and patient groups than between individuals and segments within individuals.
Alternatives To The MCMC Method

The Markov Chain Monte Carlo method (MCMC) is often used to generate independent (pseudo) random numbers from a distribution with a density that is known only up to a normalizing constant. With the MCMC method it is not necessary to compute the normalizing constant. In this paper we show that the well‐known acceptance‐rejection algorithm also works with unnormalized densities, and so this algorithm can be used to confirm the results of the MCMC method in simple cases.
Altered Subjective Time of Events in Schizophrenia

Time perception has long been known to be impaired in schizophrenia. Moreover, recent neuropsychological theories have postulated abnormalities of cognitive motor control in schizophrenia. However, the intersection of these two topics has rarely been studied, and it is unclear what role subjects’ own actions may play in the construction of subjective time representation. The present experiment compared the performance of 19 patients with schizophrenia and 24 normal controls in a timing judgment task. The results show that patients bind two consecutive movements more strongly than controls. This anomaly could play a role in the subjective pathological experiences of patients.
Knowledge transfer in creative industrial cluster: Mechanism and countermeasures

The potential developing mode of creative industry is cluster. And it is essential for creative industrial cluster promoting knowledge transfer to create knowledge advantage of cluster. Based on congregation of creative industry and knowledge transfer, this paper clarifies the characters of knowledge transfer in creativity industry cluster, and analyzes the mechanisms in creativity industry cluster from four sides: nodes, conduits, knowledge re-source and innovational environment of cluster. At last, this paper brings up some countermeasures to promote knowledge transfer within creativity industry cluster.
Dynamic audiotactile feedback in gesture interaction

Proper feedback is one of the challenges in gesture interaction. Providing continuous feedback during the execution of the gesture increases the feeling of control and it can help user to perform the task more efficiently. In this paper we introduce an experimental handheld sensor-actuator device that responds dynamically to user's motion. With the device we explored the potential of continuous audiotactile feedback in closed-loop gesture interaction, designed simple synthesis methods for feedback, and tested the user perception. We designed four simple textures that respond to overall angular velocity of the device, all with different velocity responses. The system enabled us to examine how well subjects can distinguish the textures on the fly. Our preliminary findings show that audio modality dominates the perception. Tactile feedback worked quite well alone but the modalities together didn't lead to any better performance than audio alone.
Flexible UAV Mission Management Using Emerging Technologies

Abstract : This paper discusses recent results and proposed work in the application of emerging artificial intelligence technologies for flexible mission management, especially for unmanned (combat) airborne vehicles. Military user needs are discussed for planning, monitoring and control tasks, along with relevant emerging technologies. A story board is described that depicts these military needs in the context of a scenario for countering mobile target threats. The paper concludes with a brief discussion of technical and non-technical barriers to integrating these emerging technologies within fielded systems, and an outline for the next steps.
Killer cell immunoglobulin‐like receptor along with HLA‐C ligand genes are associated with type 1 diabetes in Chinese Han population

Killer cell immunoglobulin‐like receptor (KIR) genes and their putative ligands human leukocyte antigen (HLA)‐C genes have been associated with type 1 diabetes (T1D). We hypothesize that KIR genes and their ligands HLA‐C genes are important in T1D aetiology.
A Hybrid Cognitive Engine for Improving Coverage in 3G Wireless Networks

Third generation (3G) wireless networks have been well studied and optimized with traditional radio resource management techniques, but still there is room for improvement. Cognitive radio (CR) technology can bring significant network improvements by providing awareness to the surrounding radio environment, exploiting previous network knowledge and optimizing the use of radio resources using machine learning and artificial intelligence techniques. Cognitive radio can also co-exist with legacy equipment thus acting as a bridge among heterogenous communication systems. In this paper, we present a hybrid cognitive radio engine for 3G wireless networks. The engine is designed using case-based reasoning (CBR) and decision tree (DT) searches, as the main blocks to the engine's reasoning, learning and optimization functions. The engine model was implemented and tested via simulation, it was applied to improve coverage in the network.
Comparative Evaluations of a Hierarchical Categorization of Search Results based on a Granular View of Domain Ontologies

The aim of this paper is to evaluate the effectiveness of a categorization approach of search results based on the use of domain ontologies with respect to the application of standard single-label and multi-label classification algorithms. In particular, the approach in (Calegari et al., 2011) is considered, where the categorization process is performed thanks to the adoption of a taxonomy of information represented as a granular view of a domain
MORPHOMETRIC VARIABILITY IN CONTINENTAL AND ATLANTIC ISLAND POPULATIONS OF CHAFFINCHES (FRINGILLA COELEBS)

The magnitudes of phenotypic variances in peripherally isolated populations of common chaffinches (Fringilla coelebs) in the Azores, Madeira, and Canaries relative to their continental source populations in Iberia and Morocco have played a pivotal role in the formulation of competing hypotheses of phenotypic evolution in these isolates. Because Van Valen's niche variation hypothesis and Grant's model of island evolution were based on museum skins prone to measurement error and temporal variation, we re‐examined the patterns of phenotypic variability using more precise skeletal measurements from freshly collected specimens. Levene's tests showed that univariate character variances were homogeneous in all island and continental populations, although there was a consistent trend for the magnitude of the variances to be lower for all characters in all Canary island populations. Multivariate Levene's tests, however, revealed significantly reduced total variances in the Hierro and Madeira populations compared to some Azores and continental populations. The Azores and continental populations did not differ in variability, and lower variances in the Canaries were not related to the presence or absence of the congeneric blue chaffinch (F. teydea), contrary to the predictions of Van Valen's niche variation hypothesis. Population variability was not inversely related to differentiation or isolation within the Azores or Canaries archipelagoes, opposite to the association reported by Grant. Our results also differ from both previous studies which reported much larger differences in population variabilities, and this likely reflects the use of heterogeneous samples of museum specimens, less precise external characters, and the use of tests sensitive to sample size. Differentiation among populations has been markedly greater in the Canary islands, implicating founder events and possibly historically stronger directional selection as determinants of this enhanced divergence relative to the Azores. These variance‐reducing processes are unlikely to explain current lower levels of phenotypic variability because there has been sufficient time since colonization for replenishment of variability in polygenic characters. Average heterozygosities at putatively neutral allozyme loci are 1.6 times higher in the Azores compared to the Canaries, and support the view that effective population sizes are smaller in the latter archipelago. We argue that reduced variances in the Canary island populations represent lower equilibrium levels maintained by drift and mutation in populations with smaller long‐term effective sizes, consistent with Lynch and Hill's neutral model of phenotypic evolution. Although episodes of selection in the past may have been interspersed with long periods of effective neutralism and drift, adaptationist hypotheses invoking a primary role for variance‐reducing selection appear to be unwarranted.
Synthesis of heteroleptic anthryl-substituted beta-ketoenolates of rhodium(III) and iridium(III): photophysical, electrochemical, and EPR study of the fluorophore-metal interaction.

The anthryl-substituted rhodium(III) and iridium(III) heteroleptic beta-ketoenolato derivatives of general formula [M(acac)(2)(anCOacac)] [acac = pentane-2,4-dionate; anCOacac = 3-(9-anthroyl)pentane-2,4-dionate], 3 (M = Rh) and 4 (M = Ir), and [M(acac)(2)(anCH(2)acac)] [anCH(2)acac = 3-(9-anthrylmethyl)pentane-2,4-dionate], 5 (M = Rh) and 6 (M = Ir), were prepared by reacting the corresponding tris(pentane-2,4-dionate)metal complexes, [M(acac)(3)], with 9-anthroyl chloride and 9-chloromethylanthracene, respectively, under Friedel-Crafts conditions. 3-6 were characterized by elemental analysis, ion spray mass spectrometry (IS-MS), (1)H NMR, and UV-vis spectroscopy. The structure of 3 was also elucidated by single-crystal X-ray analysis. When excited at 365 nm, 3-6 result to be poorly luminescent compounds; while the free diketone, i.e., 3-(9-anthrylmethyl)pentane-2,4-dione 1, whose structure was established also by single-crystal X-ray analysis, results to be a strongly light emitting molecule. The study of the electrochemical behavior of 3-6 as well as of the corresponding tris-acetylacetonates of rhodium(III) and iridium(III) allows a satisfactory interpretation of their electrode process mechanism, and gives information about the location of the redox sites along with the thermodynamic and kinetic characterization of the corresponding redox processes. All data are in agreement with the hypothesis that the quenching of the anthracene fluorescence, observed for compounds 3-6, can be due to an intramolecular electron transfer process between the anthryl moiety and the metal-beta-ketoenolato component. Moreover, a study was carried out of the redox behavior of the dyads 3-6 under chemical activation. The one-electron oxidation of compounds 3-6 by thallium(III) trifluoroacetate leads to the formation of the corresponding cation radicals, 3(+)-6(+), whose highly resolved X-band EPR spectra were fully interpreted by computer simulation as well as by semiempirical and DFT calculations of spin density distribution.
Comparison of Shear Stress–Induced Platelet Microparticle Formation and Phosphatidylserine Expression in Presence of &agr;IIb&bgr;3 Antagonists

The use of platelet glycoprotein IIb-IIIa (&agr;IIb&bgr;3) antagonists is an accepted practice in the treatment of acute coronary syndromes. Recent studies have demonstrated that &agr;IIb&bgr;3 receptor antagonists are effective in inhibiting the procoagulant activity of platelets under static conditions. No investigation, however, has compared the ability of these platelet antagonists to inhibit platelet procoagulant activity, defined as an increase in phosphatidylserine (PS) expression, under conditions of shear stress. Thus, the goal of this study was to quantify the amount of microparticle formation and PS expression of platelets exposed to physiologic and pathophysiologic levels of shear stress in the absence and presence of three clinically approved parenteral &agr;IIb&bgr;3 antagonists (abciximab, eptifibatide, and tirofiban). Flow cytometric results demonstrated that although microparticle formation was significantly inhibited by all three antagonists, PS expression by sheared platelets was affected differently depending on the antagonist present. Specifically, abciximab suppressed PS expression compared with the saline control; both abciximab and eptifibatide significantly reduced PS expression compared with tirofiban; and tirofiban potentiated PS expression relative to the saline control at the highest shear stress. This is the first demonstration of differential regulation of platelet PS expression and, by inference, procoagulant activity in the presence of &agr;IIb&bgr;3 receptor antagonists under shear stress. The current results may have future importance in improving the design of platelet antagonists as well as defining the general role of fluid shear stress in platelet thrombus formation.
A DCT-based spatially adaptive post-processing technique to reduce the blocking artifacts in transform coded images

We propose a discrete cosine transform (DCT)-based post-processing technique to alleviate the blocking artifacts in transform coded images. In our approach, the high-frequency components, mainly caused by the edge components, are examined through two steps. First, two adjacent homogeneous blocks from the block boundary are found, where the homogeneous block is defined as the block in which no adjacent pixels' difference is larger than the difference of the block boundary. Second, the local frequency characteristics in the homogeneous block are examined through the DCT. Then, we derive the relation between the DCT coefficients of two homogeneous blocks of different sizes. By considering the information about the original edge and the relation, we can detect the high-frequency components, mainly caused by the blocking artifact. The performance of the proposed technique is evaluated on both still and moving images. The simulation results indicate that the proposed technique reduces the blocking artifacts effectively and preserves the original edges faithfully, and its performance is very robust to the degree of degradation in the decoded images.
An unusual chromosomal segregation in a family with a translocation between chromosomes 3 and 12

A family is reported in which two infants were born with different types of congenital abnormalities. Chromosome studies on one of the infants showed a partial trisomy of the short arms of a No. 3 chromosome. A family study showed many balanced translocation carriers who had extra chromosomal material on the long arms of a No. 12 chromosome.
Preliminary study on haptic-stimulation based brainwave entrainment

Auditory or visual stimulation has been widely used for brainwave entrainment, i.e. to modulate brain electroencephalograms (EEG) signals into a specific target frequency band. In this work, we study whether similar phenomena exists with haptic stimulation. By using a Phantom desktop to provide a sinusoidal force stimulation to a human subject's hand, and using a Nexus EEG device for real-time brain signal monitoring, we test how the Sensory Motor Rhythm (SMR) signal and the Alpha signal of the subject responds to the haptic stimulation. Our experiments show that the energy level of SMR signal tends to increase considerably (on average 10~30% of 8 human subjects) after 10-15 minutes of haptic stimulation with a 15Hz stimulation signal, and the energy level of Alpha signal tends to decrease considerably (on average 10~30% of 8 human subjects) after 10-15 minutes of haptic stimulation with a 10Hz stimulation signal. These results may have potential application in training human concentration and/or relaxation skills.
Biosynthesis of 4-Aminobenzoate in Escherichia coli

Two different mutations (pabA and pabB) affecting 4-aminobenzoate biosynthesis were obtained in strains of Escherichia coli lacking chorismate mutase and anthranilate synthetase activity, thus allowing study of the pathway of biosynthesis of 4-aminobenzoate by use of cell extracts of strains carrying the pab mutations. Two components with approximate molecular weights of 9,000 (component A) and 48,000 (component B) are concerned in the biosynthesis of 4-aminobenzoate from chorismate by E. coli. No diffusible intermediate compound could be detected.