Miracle-dz/UniFAR-FTUs huggingface dataset:
Evaluation of Antihyperglycemic Effect of Epilobium parviflorum in High Fat Diet Fructose Streptozotocin Induced Type 2 Diabetic Albino Wistar Rats

The proposed work deals with pharmacological evaluation of aqueous leaf extract of Epilobium parviflorum for antihyperglycemic and antihyperlipidemic activity in high fat diet fructose streptozotocin induced type 2 Diabetes mellitus in albino wistar rats. The experimental protocol was designed on a total of 30 rats, equally divided into 5 groups (6 rats in each group). The high fat diet fructose was administered to all the groups except the normal control group throughout a 6 w study period. A low dose of streptozotocin (35 mg/kg body weight) is freshly prepared and administered intraperitoneally once after the initial 2 w of high fat diet fructose administration. The animals were observed for 1 w to induce diabetes. The two doses of aqueous leaf extract of Epilobium parviflorum (200 & 400 mg/kg) and pioglitazone (10 mg/kg) were administered orally once daily throughout the rest 3 w. Various serum parameters including lipid profile, liver profile, renal profile and inflammatory biomarkers were estimated on 0th and 6th w of the study. All the individual test results are falling within the normal distribution of the test groups (treatment with leaf extract) when compared with disease control group with least variance (p<0.01). However, when compared to the standard group (pioglitazone treated), the results show too much variance. Increase in insulin release and decreased fasting blood sugar results are purely dose dependant. The histopathological studies of hepatocyte, nephron, adipocytes and islet of pancreatic beta cells were also exhibited excellent antihyperglycemic and antihyperlipidemic activity while the test group maintained normal cell architectures. With the assumption on the traditional curative assurance and scientific evidences, it may be concluded that Epilobium parviflorum contributes to the antihyperglycemic as well as antihyperlipidemic activity by maintaining the normal structure and function of hepatocytes, renal, pancreas and adipose function.
Bioinformatics Identification of Green Tea Anticancer Properties: a Network-Based Approach

Background and objectives: Promising anticancer properties are associated with the consumption of green tea. On the other hand, lung cancer has been showing to possess the highest number of death compared to other types of cancer. The aim of this study was to understand the mechanisms by which green tea shows this effect; bioinformatics study of proteome profile could be essential. For this reason, the proteomics analysis of human lung adenocarcinoma A-549 cells treated with green tea extract was chosen for protein-protein interaction (PPI) network analysis. Methods: Cytoscape v.3. 8.2 and its applications analyzed a number of 14 differentially expressed proteins (DEPs) from green tea treatment experiment as two networks. The biological annotations and action type exploration of the hub-bottlenecks of the PPI network were then carried out. Results. The investigation indicated that among 14 queries DEPs, HNRNPA2B1, PCBP1, and HNRNPC may show substantial role. Moreover, HSPA8 was the top hub-bottleneck and half of the central protein groups were enriched with heterogeneous nuclear ribonucleoproteins complex family (HNRNPs). Conclusion. The anticancer bioinformatics study of green tea suggests a complex nature for green tea. This finding urges complementary evaluations to validate whether green tea is applicable as an anticancer agent in medicine.
Euphorbia helioscopia: chemical constituents and biological activities

Euphorbia, the largest genus in the spurge family “Euphorbiaceae” with more than 2000 species and is subdivided into many subgenera and sections. Several species of the genus Euphorbia have been extensively studied for their antiviral, antitumor, cytotoxic, antimicrobial and pesticidal activities. Based on traditional information, Euphorbia helioscopia has been widely used in the traditional folk medicine in China and Turkey. Up to now, 30 diterpenoids have been isolated and structurally characterized from this plant. The aim of the present work is to review all the available scientific literatures published on E. helioscopia. The focus will be on the chemical constitutions that have been identified from this species, in addition, all the reported biological, pharmacological and toxicological activities of different extracts and isolates from this species have been included. The paper recommends the need for further investigations regarding the environmental and mammalian safety of E. helioscopia for safer using in different biological and therapeutic applications.
ROTORDYNAMIC ANALYSIS OF HIGH-SPEED ROTOR USED IN CRYOGENIC TURBOEXPANDER

The size of advanced turbomachines such as turbocharger, turbo compressor, turbo-alternator, and turbo expander is decreasing to make it more compact. The decreasing size leads to high speed for better efficiency of the turbomachinery. The high-speed rotors are subjected to transverse vibration due to unbalance load and external radial load. The rotor dynamics study of such rotor is essential to estimate the level of vibration by predicting its critical speeds, mode shapes, and unbalanced response. In the present work the critical speeds, mode shapes, and unbalance response are predicted for a prototype rotor-bearing system used in cryogenic turboexpander. The designed rotational speed of the rotor is 2, 40, 000 rpm with radial unbalance near the bearing location is 40mg-mm. This paper presents the rotordynamic analysis of the rotor using commercial finite element analysis software ANSYS®. The author believes the detailed finite element analysis will be quite useful of the researchers around the world.
Computer Simulations of Continuous 3-D Printing

3-D printing is a revolutionary manufacturing technique which makes it possible to fabricate objects of any shape and size that are hard to reproduce by traditional methods. We develop a coarse-grained molecular dynamics simulation approach to model the continuous liquid interface production (CLIP) 3-D printing technique. This technique utilizes a continuous polymerization and cross-linking of the liquid monomeric precursor by the UV light within a thin layer while pulling the cross-linked polymeric object out of a pool of monomers. Simulations show that the quality of the shape of the 3-D printed objects is determined by a fine interplay between elastic, capillary, and friction forces. Using simulation results, we identify the source of the object shape deformations and develop a set of rules for calibration of the parameters to meet the accuracy requirements. Comparison between different continuous 3-D printing setups shows that proposed modifications of the printing process could improve quality and ac.
Diversity analysis in Arachis subspecies using phenotypic characterization and microsatellite (SSR) markers

Groundnut (Arachis hypogaea L.) is one of the important economic crops of the world. It is the world’s fourth most important source of edible oil and third most important source of vegetable protein. A study was conducted at Department of Seed Science and Technology, B. A. College of Agriculture, AAU, Anand, to investigate morphological and molecular characterization in different Arachis spp. The experiment was laid out in randomized complete block design with two replications and evaluated for 28 quantitative and 20 qualitative characters. Genetic distances among the genotypes obtained from the analysis of 20 qualitative traits ranged from 1.00 between the pairs ICG1994 and AG2245 and upto 9.70 between pairs ICG6813 and JB1180. Dendrogram developed using average taxonomic distance matrix by UPGMA method formed four major clusters. The dendrogram could not establish any distinct relationship between different botanical groups. However, few genotypes belonging to spanish bunch group tend to cluster together exhibiting their common phylogenetic relationship. This was also evident in the case of Virginia bunch cultures where a common phylogenetic relationship was observed. Pooled SSR analysis of 50 groundnut genotypes using 23 SSR primers generated a total of 1293 scorable bands with 251 alleles. The average PIC value was 0.670. The average genetic similarity coefficient obtained by using SSR markers for different genotypes in this study was 0.27.
Selective cleavage of ester linkages of anhydride-cured epoxy using a benign method and reuse of the decomposed polymer in new epoxy preparation

Thermosetting polymers possess high dimensional stability, chemical resistance and thermal stability, and they are indispensable for many applications. However, conventional thermosetting polymers cannot be reprocessed and reshaped due to their permanent cross-linked structure. Therefore, recycling of thermosetting polymers is a serious challenge. Degrading thermosetting polymers into soluble oligomers and reuse of the oligomers in new resin systems may provide a favorable way to solve this problem. In this work, we developed an efficient method for chemical degradation of anhydride-cured epoxy using environmentally benign phosphotungstic acid (HPW) aqueous solution as the catalyst system at a mild reaction temperature of 190 °C. During reaction, the ester bond in the cross-linked structure was selectively cleaved, and the thermosetting polymer was fully converted to oligomers that contain multifunctional reactive groups. When the decomposed matrix polymer (DMP) was used as a reactive ingredient and added up to 40 wt% in the preparation of a new anhydride-cured epoxy curing system, the resulting cross-linked polymers still retained the mechanical properties of the neat polymer.
HYBRID COOLING DESIGN OF PERMANENT MAGNET SYNCHRONOUS MACHINES

This paper presents the challenges of creating a cooling system for a permanent magnet machine with high power density. A hybrid air/water cooling system is presented with the aim of enhancing the cooling performance of the stator. Finite element calculations are first used to determine the winding loss in the stator, including skin and proximity effect. The effect of air speed, turbulence of the air flow and liquid speed have been discussed to find the best working point, using CFD simulation. The performance of the hybrid cooling system has been evaluated and design recommendations established.
The Acceptance Study of e-commerce Customers Based on TAM

The improvement of information technology and science has grown rapidly. CV. Sukses Mandiri Jaya, which is engaged in the sale of spare parts for motorcycle, does not have a computerize system, making it difficult for buyers to see the products and to make transactions. The work aim to create a web based system with the Technology Acceptance Model (TAM) to measure the usability level of the system. TAM is used to achieve a certain goal by identifying some of the basic variables and by measuring factors that affect system acceptance. TAM positions two beliefs, that are Perceived Usefulness and Perceived Ease of Use as major factors in system acceptance behavior. It was found that the proposed system accepted by customers, which was measured by a questionnaire involving 57 respondents. The results show that Perceived Usefulness and Perceived Ease of Use simultaneously and partially have positive and significant influence on the Behavior Intention. This also shows that result of the relative contribution of perceived usefulness (X1) is 36.75% and the perceived ease of use (X2) is 63.25%. The effective contribution of Perceived Usefulness is 29.44% and the Perceived Ease of Use is 50.66% for Behavior Intention, which means that the effect of Perceived Ease of Use is more dominant than the Perceived Usefulness
Isolation, Biochemical Characterisation and Identification of Thermotolerant and Cellulolytic Paenibacillus lactis and Bacillus licheniformis

SUMMARY Research background Cellulose is an ingredient of waste materials that can be converted to other valuable substances. This is possible provided that the polymer molecule is degraded to smaller particles and used as a carbon source by microorganisms. Because of the frequently applied methods of pretreatment of lignocellulosic materials, the cellulases derived from thermophilic microorganisms are particularly desirable. Experimental approach We were looking for cellulolytic microorganisms able to grow at 50 °C and we described their morphological features and biochemical characteristics based on carboxymethyl cellulase (CMCase) activity and the API® ZYM system. The growth curves during incubation at 50 °C were examined using the BioLector® microbioreactor. Results and conclusions Forty bacterial strains were isolated from fermenting hay, geothermal karst spring, hot spring and geothermal pond at 50 °C. The vast majority of the bacteria were Gram-positive and rod-shaped with the maximum growth temperature of at least 50 °C. We also demonstrated a large diversity of biochemical characteristics among the microorganisms. The CMCase activity was confirmed in 27 strains. Hydrolysis capacities were significant in bacterial strains: BBLN1, BSO6, BSO10, BSO13 and BSO14, and reached 2.74, 1.62, 1.30, 1.38 and 8.02 respectively. Rapid and stable growth was observed, among others, for BBLN1, BSO10, BSO13 and BSO14. The strains fulfilled the selection conditions and were identified based on the 16S rDNA sequences. BBLN1, BSO10, BSO13 were classified as Bacillus licheniformis, whereas BSO14 as Paenibacillus lactis. Novelty and scientific contribution We described cellulolytic activity and biochemical characteristics of many bacteria isolated from hot environments. We are also the first to report the cellulolytic activity of thermotolerant P. lactis. Described strains can be a source of new thermostable cellulases, which are extremely desirable in various branches of circular bioeconomy.
Effective adsorptive removal of 2,4,6-trinitrotoluene and hexahydro-1,3,5-trinitro-1,3,5-triazine by pseudographitic carbon: kinetics, equilibrium and thermodynamics

Environmental context Explosive organic compounds such as 2,4,6-trinitrotoluene (TNT) and hexahydro-1,3,5-trinitro-1,3,5-triazine (RDX) are major constituents of ammunition materials. These compounds are of environmental concern because they can have a significant impact on ecosystems and humans. Through investigations of adsorption kinetics, isotherms and thermodynamics, we demonstrate the suitability of pseudographitic carbon for removing TNT and RDX from groundwater, and additionally confirm the viability of the use of pseudographitic carbon through comparison with other adsorbents. Abstract 2,4,6-Trinitrotoluene (TNT) and hexahydro-1,3,5-trinitro-1,3,5-triazine (RDX) – common explosives in military munitions – can easily enter groundwater supplies and have an adverse impact on human health. There is great concern about the need to remove these explosives from groundwater, and this study presents pseudographitic carbon (PGC) prepared from edible sugar as a material to remove explosives from contaminated groundwater via adsorption. The purity and physicochemical characteristics of the PGC were characterised using advanced spectroscopic techniques. The adsorption mechanism and its efficiency were investigated in terms of the non-linear adsorption kinetics, isotherms and thermodynamics using TNT and RDX adsorption data. The results of the non-linear modelling indicate that TNT and RDX adsorption was determined by rate-limiting monolayer exothermic adsorption on the homogeneous PGC surface. Ionic strength was studied with various ions, and the results indicate that the adsorption of TNT and RDX was significantly influenced by divalent cations and the carbonate anion. The results of desorption and re-use tests indicate that acetone and acetonitrile are the best desorbing agents. The PGC can be recycled and re-used for up to 3 cycles, with insignificant loss in adsorption efficiency. Finally, the PGC was applied to real spiked groundwater to evaluate its applicability in the field in removing TNT and RDX. The overall results indicate that PGC is a cost-effective and efficient adsorbent that effectively removes the organic explosives from groundwater, thereby reducing risk to humans and the aqueous environment.
Internal force calculation of long span suspension bridge under vertical load based on elastic foundation beam algorithm

The calculation of suspension bridge under vertical load is the most important content of suspension bridge design calculation and the most important basis of main component design. Combined with the knowledge of structural mechanics, this paper puts forward the elastic foundation beam algorithm, and deduces the important formulas for the cross-section design and strength comparison of sling, cable and stiffening beam. In use, as long as the parameters are brought into the formula, it is more convenient and fast compared with the complex software modeling. The method proposed in this paper is used to check the strength of the completed Japanese Guanmen bridge, and the results are accurate enough. It is fast and reliable to use this method in the preliminary design and rapid safety assessment of suspension bridge.
Political marketing: impact of public relations on the change in voter behaviour of consumers (voters)

Companies use marketing public relations to support the marketing department or product promotion and image-making. The discipline of public relations usually used to be of secondary importance in marketing communication activities for ages. Marketing public relations could affect public awareness at a fraction of the cost of advertising and is often much more credible. Public relations are intended to positively influence development in society by aligning one's own interests with those of the public. Public relations objectives in politics focus on building image, securing market share, or increasing consumer (voter) conviction. Political parties should inform the public of their activities based on truthfulness and without any distortion. The paper aims to theoretically summarize public relations and differences between public relations and advertising and an analysis of the impact of public relations and public relations tools on the change of voting behavior and decision-making of Slovak consumers (voters). The empirical study was carried out based on a research of 362 in Slovakia consumers (voters). The primary information was the actual collection. The sample consisted of 362 respondents. The obtained primary data were processed in the statistical program. The method Pearson's Chi-squared test was used to confirm or reject the stated hypothesis. The subject of the research were consumers living in the region of eastern Slovakia. The obtained results showed statistically significant differences in the perception of tools and public relations methods depending on respondents' education. The findings could be beneficial for several target groups, namely marketing managers in the political field, political parties, political candidates, not only in Eastern Slovakia but within the framework of whole Slovakia. At the same time, they could serve as a source of information and as a basis for deciding and establishing the right tools of public relations in promoting political parties and political candidates.
Gini Indices II and III: Two new Sparsity Measures and Their Applications to Machine Condition Monitoring

Machine condition monitoring (MCM) uses signal processing and machine learning methods to analyze monitoring data and perform timely condition-based maintenance. Since monitoring data usually have a sparsity property, sparsity measures (SMs) are naturally considered to quantify the sparsity of signals and they serve as the objective functions of many signal processing and machine learning methods. Although Gini index, kurtosis, smoothness index, negative entropy, and Lp/Lq norm have been considerably investigated for MCM, the design of new SMs for enhancing MCM is rarely reported. In this article, based on the ratio of different quasi-arithmetic means (RQAM), two new SMs, coined as Gini index Ⅱ (GI2) and Gini index Ⅲ (GI3), are designed. New proofs show that the GI2 and GI3 satisfy all six sparsity attributes. Subsequently, the GI2 and GI3 of the square envelope of Gaussian white noise are theoretically investigated and their theoretical values are, respectively, equal to 2/3 and 1/3, which can be used as baselines for machine abnormality detection. Once GI2 and GI3 exceed the baselines, abnormal health conditions can be detected without needing historical data and prior fault knowledge. Finally, simulated and experimental case studies showed that the proposed GI2 and GI3 have competitive performance with Gini index and that they are better than kurtosis, negative entropy, and smoothness index, in characterizing the sparsity of signals. This article demonstrates that the RQAM is a potential framework to design new SMs.
Comparison of Energy Estimates of Mixed Diets Obtained from RIVIGPT and In-vivo Digestibility Trial in NariSuwarna X Kenguri F1 Sheep -

To compare the energy estimates of mixed diets obtained from rumen in vitro incubation for gas production (RIVIGP) and digestion trial (DT) in NariSuwarna X Kenguri F1 sheep, twenty four sheep were divided into six groups of five each. Six mixed diets were prepared by using sugarcane trash and concentrate feed mixture in the ratio of T-1 80:20, T-2 70:30, T-3 60:40, T-4 50:50, T-5 40:60 and T-6 30:70. The feeding trial was carried out for the duration of six weeks with an adjustment period of five weeks and collection period of one week. The metabolisable energy (ME, MJ kg-1 DM) content of diets at maintenance level of intake obtained by DT for diets-1, 2, 3, 4, 5 and 6 were 6.7, 6.9, 7.4, 7.2, 7.8 and 9.4 respectively. The corresponding ME values obtained from RIVIGP were 5.3, 5.9, 6.2, 7.5, 8.6 and 9.4 respectively. The difference between the ME obtained from DT (digestion trial) and ME predicted from RIVIGPT was found to be 10.7 per cent. The mean ME output (Maintenance + weight gain) for the diets-1, 2, 3, 4, 5 and 6 were 6.37, 6.34, 7.38, 7.70, 8.06 and 8.27 respectively. The ME intake estimated from ME obtained from DT and RIVIGP for the diets-1, 2, 3, 4, 5 and 6 were 4.91 and 3.79, 5.02 and 4.22, 7.63 and 6.46, 7.74 and 8.13, 8.76 and 9.81, 11.42 and 11.85 respectively. Hence, the observed performance of NariSuwarna x Kenguri F1 sheep expressed in terms of the total ME output was accountable to the extent of 97.0 and 99.6% of ME intake estimates obtained from ME values derived by DT and RIVIGP respectively.
Joint Transceiver Design for Radar-Communication Spectral Sharing Systems by Minimizing Effective Interference Power

This brief investigates a spectrum sharing architecture for a colocated MIMO radar and a MIMO communication system. We develop an alternative formulation for joint resource allocation, aiming at minimizing the effective power of radar interference under the power and similarity constraints. The communication system mutual information (MI) is also simultaneously concerned in order to guarantee the communication performance. The degrees of freedom for system design are both the radar transceiver and the communication transmitter. For the joint designed original non-convex problem, an alternating iterative algorithm with multi-subproblems is derived based on the majorization-minimization algorithm, minimum variance distortionless response (MVDR) and semidefinite programming (SDP) algorithm. The convergence of the algorithm is guaranteed. Finally, we assess the effectiveness of the proposed approach via numerical results.