Miracle-dz/UniFAR-FTUs huggingface dataset:
Diagnostic accuracy of D-dimer assay in detection of pulmonary embolism in patients presenting in emergency department

Background: Pulmonary embolism is the lethal condition that is associated with higher rate of mortality in cardia patients. The diagnosis of the acute pulmonary embolism is frequently observed in patients presenting in emergency department or during hospitalization. Level of D-dimer may be assessed by blood test to help the physicians to diagnose the thrombosis. Literature showed variable evidence regarding predictive accuracy of D-dimer for detection of pulmonary embolism. So to get local data, we conducted this study. Aim: To determine the diagnostic accuracy of D-dimer assay for detection of pulmonary embolism in patients of acute myocardial infarction presenting in emergency department taking CTPA as gold standard Methods: Cross - sectional study conducted in Cardiology Department , Punjab Institute of Cardiology, Lahore for a period of six months from 1-9-2018 to 1-3-2019. One hundred patients, fulfilled the selection criteria were enrolled from emergency. Then blood sample was taken for evaluation of D-dimer level. Reports were checked and D-dimer level was noted. Pulmonary embolism was labeled as positive on D-dimer, if D-dimer level ≥500 and was labeled as negative if D-dimer level <500. Then all patients underwent CTPA. Pulmonary embolism labeled as positive if there was mass filling defects detected as dark spot on angiogram. All the data was collected by using the proforma. Data analysis as done in SPSS v. 21. Results: The mean age of patients was 54.03±10.26years. There were 40 (40) males and 60 (60%) females. The mean BMI of patients was 27.57±4.35kg/m2. There were 46 (46%) patients with diabetes mellitus while 61 (61%) patients had hypertension. The sensitivity, specificity, PPV, NPV and diagnostic accuracy of D-dimer were 82.6%, 72.2%, 71.7%, 83.0% and 77.0%, respectively taking CTPA as gold standard. Conclusion: Thus the D-dimer is accurate enough that it can help to predict pulmonary embolism and can help to prevent at least negative cases to undergo CTPA. Keywords: Acute myocardial infarction, pulmonary embolism, D-dimer, computed tomography pulmonary angiography
Code design and performance analysis in TCCPM system based on super trellis

This paper describes a technique related to the design of a trellis encoder, combined with the continuous phase modulation (CPM). Based on the idea of decomposing CPM into continuous phase encoder (CPE) and memoryless modulator (MM), superior trellis encoders are designed following Ungerboeck's set partitioning rules. Combinations are optimized with the squared minimum Euclidean distance based on the super trellis structure constructed by the trellis structure of trellis coded modulation (TCM) and CPE. Simulation results show that this new coding scheme consistently obtains better performance than previous schemes. © 2013 Institute of Electrical Engineers of Japan. Published by John Wiley & Sons, Inc.
Factors influencing online shopping intentions: The mediating role of perceived enjoyment

The study aimed to understand factors influencing customers' online shopping intentions. This study used the technology acceptance model (TAM) and extended it, including social value and perceived enjoyment, to measure customers' intentions in the online shopping context. Three hundred one validated data was collected using personal interviews and the online survey approach through convenience sampling technique from 20 to 60 years old. Subsequently, data were analyzed through PLS-SEM. The measurement model was first examined to determine whether the constructs predict online shopping intentions. After validating the measurement model, the subsequent structural model was analyzed using Smart PLS 3.3. 3. The study results revealed that perceived usefulness, attitude, social value, and perceived enjoyment are significant positive predictors of online shopping intentions. However, perceived ease of use insignificantly impacted online shopping intentions. Moreover, this study results showed that perceived enjoyment partially mediates the relationship between perceived usefulness, perceived ease of use, social value, and online shopping intentions. In contrast, the influence of attitude on intentions is insignificantly mediated by perceived enjoyment. This study will provide online e-retailers with insights into how practitioners can influence customers to shop online. Customer behaviour is the result of customers' intentions, built through perceived usefulness, ease of use, attitude, social value, and enjoyment.
INTO THE FRAY: SHIFTING FACTORS AFFECTING THE DIFFUSION OF COMMERCIALIZED SCIENCE IN HIGHER EDUCATION

Universities have resisted commercializing technology for the greater part of this past century. Until recently, only a small number of universities transferred their technology to the public, but now commercialized science is widespread. This study explores how the field grew and how different factors affected the diffusion of this once illegitimate practice over time. Specifically, this study investigates the adoption of technology transfer offices – university employees committed to facilitate the transfer of university technology for commercial use – and how universities’ status, identity, and exposure to prior adopters differentially motivated their engagement in this activity over time.
Implementation Mode of Industrial Engineering Projects Based on Project Management

Since the Industrial Engineering (IE) was introduced to China, people have already had much understanding of this cross discipline, and IE has been successfully popularized and applied in some enterprises. In such circumstances, a task we face is to systematically and comprehensively develop a theory and application system of IE from the subject development and practical application point of view, and the industrial engineering body of knowledge is established based on such a need. In this paper, on the basis of investigation and study on the domestic and foreign relevant studies, it establishes the industrial engineering body of knowledge, and proposes the implementation mode of IE projects based on project management, providing a certain reference role in the discipline development of IE and the implementation of IE in enterprises.
Valosin-containing protein regulates the stability of amyotrophic lateral sclerosis-causing fused in sarcoma granules in cells by changing ATP concentrations inside the granules

Fused in sarcoma (FUS) undergoes liquid-liquid phase separation (LLPS) to form granules in cells, leading to pathogenic aggregations that cause neurodegenerative diseases, including amyotrophic lateral sclerosis (ALS). Proteomics analysis revealed that FUS granules contain valosin-containing protein (VCP), a member of the AAA family ATPase. Confocal microscopy images showed that VCP co-localized in the FUS granules in cells. This study demonstrates that VCP in granules has a two-faced role in FUS granulation: VCP stabilizes de novo FUS granules, while VCP present in the granules for extended periods dissolves them. This VCP function relies on its ATPase activity to consume ATP in granules. VCP stabilizes de novo FUS by reducing intragranular ATP concentrations to a range below the cytosolic concentration. VCP continually consumes ATP during its stay in the granules, which eventually lowers ATP concentrations to a range that destabilizes the granules. VCP, therefore, acts as a timer to limit the residence of FUS granules in cells and thereby prohibits the FUS fibrillization that occurs in persistent granules. VCP ATPase activity plays a role in FUS granule turnover. Summary statement VCP recruited to FUS granules regulates the stability of the granules in a time-dependent manner by consuming intragranular ATP with its ATPase activity.
Right ventricular function and its coupling to pulmonary circulation predicts exercise tolerance in systolic heart failure

Right ventricular (RV) dysfunction, pulmonary hypertension, and exercise intolerance have prognostic values, but their interrelation is not fully understood. We investigated how RV function alone and its coupling with pulmonary circulation (RV‐PA) predict cardio‐respiratory fitness in patients with heart failure and reduced ejection fraction (HFrEF).
COVİD-19 pandemi sürecinde havacılık sektöründe çalışanların örgütsel bağlılığının işten ayrılma niyetlerine etkisinin belirlenmesi

Bu araştırmanın amacı havayolu sektöründe çalışan personellerin örgütsel bağlılıklarının işten ayrılma niyetine etkisinin pandemi süreci göz önüne alınarak incelenmesidir. Araştırma modelinde örgütsel bağlılık; duygusal, devam ve normatif bağlılık olmak üzere iç alt faktör olarak ele alınmıştır. Araştırmada kolayda örneklem yöntemiyle 566 anket formu toplanmıştır. Elde edilen veriler Smart PLS-SEM istatistik programında kovaryans bazlı yapısal eşitlik modeli yöntemiyle analize tabi tutulmuştur. Araştırma sonuçlarına göre personellerin çalıştıkları yere yönelik normatif bağlılıkları işten ayrılma niyetlerini negatif yönde etkilemektedir. Ancak personellerin duygusal ve devam bağlılıkları işten ayrılma niyetini negatif yönde etkilememektedir.
Introducing NMR to Biomedical Laboratory Scientists through a Laboratory Exercise; Synthesis, Structure Determination and Quantization of Aspirin by Employing an 1H-NMR Bench Top Instrument

In this chemical education research study, NMR was introduced to a group of 3 students with minor chemistry background. A bench top NMR instrument was used to acquire the 1 H-NMR spectra. The 1 H-NMR spectra were used to monitor the synthesis of ASA and product purity. The spectrum of the product confirmed its formation, and the spectra of crude and final product allowed the students to observe the elimination of impurities upon recrystallization of the product. Further, the spectrum of the final product was used to quantify the yield through integration of the proton resonances. The use of integrals of the proton resonances for calculation of the yield of ASA is to our knowledge not described elsewhere in undergraduate experiments. A procedure for the synthesis, recording and processing of 1 H-NMR spectra, as well as calculation of the yield is reported. This procedure can be implemented by undergraduate or by high school students and might as well be useful for instructors who wants to introduce NMR spectroscopy early in the curriculum of Chemistry. By including an exercise like this, the students get hands on experience to employ advanced technology that might be commonly used in the future, also in Hospital laboratories. Furthermore, it is useful to introduce one of the most demanding and advanced methods in chemistry as early as possible in the curriculum in Chemistry to promote the chemistry career.
Explanation-based learning of diagnostic heuristics: a comparison of learning from success and failure

The author compares strategies of learning from failures to learning from successes in the context of a generate-and-test problem solver. One result is fairly straightforward: failure-driven learning creates rules which distinguish between failures. This is demonstrated by the fact that the number of hypotheses decreases after learning. A more subtle result is that the performance of the system, measured in terms of logical inferences, decreased with failure-driven learning more than it did with two variants of success driven learning. Diagnosis results are presented for ACES designed to process telemetry data from a satellite and isolate the cause of problems with the attitude control system. <<ETX>>
Long-Term In Vitro Passaging Had a Negligible Effect on Extracellular Vesicles Released by Leishmania amazonensis and Induced Protective Immune Response in BALB/c Mice

Depending on Leishmania species and the presence/absence of virulence factors, Leishmania extracellular vesicles (EVs) can differently stimulate host immune cells. This work is aimed at characterizing and evaluating the protective role of EVs released by Leishmania amazonensis promastigotes under different maintenance conditions. Initially, using a control strain, we standardized 26°C as the best release temperature to obtain EVs with a potential protective role in the experimental leishmaniasis model. Then, long-term (LT-P) promastigotes of L. amazonensis were obtained after long-term in vitro culture (100 in vitro passages). In vivo-derived (IVD-P) promastigotes of L. amazonensis were selected after 3 consecutive experimental infections in BALB/c mice. Those strains developed similar lesion sizes except for IVD-P at 8 weeks post infection. No differences in EV production were detected in both strains. However, the presence of LPG between LT-P and IVD-P EVs was different. Groups of mice immunized with EVs emulsified in the adjuvant and challenged with IVD-P parasites showed decreased lesion size and parasitic load compared with the nonimmunized groups. The immunization regimen with two doses showed high IFN-γ and IgG2a titers in challenged mice with either IVD-P or LT-P EVs. IL-4 and IL-10 were detected in immunized mice, suggesting a mixed Th1/Th2 profile. EVs released by either IVD-P or LT-P induced a partial protective effect in an immunization model. Thus, our results uncover a potential protective role of EVs from L. amazonensis for cutaneous leishmaniasis. Moreover, long-term maintenance under in vitro conditions did not seem to affect EV release and their immunization properties in mice.
COVİD-19 döneminde evden çalışma ve çalışanların görev performansı: Çağrı merkezi çalışanlarında bir araştırma

COVİD-19 salgını, tüm dünya ile birlikte ülkemizi de etkisi altına almış ve işletmelerin çalışma sistemlerinde köklü değişikliklere gidilmesine sebep olmuştur. Bazı işletmeler, çalışanlarının haftanın belirli günlerinde işyerinden, arta kalan günlerde ise evlerinden çalışmalarını isterken bazı işletmeler ise belli görevleri ifa eden çalışanlarının tümüyle evlerinden çalışmalarını istemişlerdir. Evden yapılan çalışmalarda doğrudan denetim olmaması, kişilerin özel hayatlarıyla çalışma hayatları arasındaki sınırın ortan kalkması, çalışanların ev ortamının rahatlığında ve güvenli bir alanda görevlerini yerine getiriyor olmaları, kendilerine vakit ayırabiliyor olmaları ve özellikle ev ve işyeri arasındaki ulaşım süresinin yaşanmıyor olması, evden çalışan kişilerin algıladıkları görev performanslarında, işyerinde çalışmak zorunda olan kişilere göre farklılık oluşturması gerektiği düşüncesiyle yapılan bu çalışma, çalışanlardan, COVİD-19 öncesi işyerinde çalıştıkları sürede ve sonrasında evden çalıştıkları süredeki genel görev performansları ve yaptıkları işe yönelik spesifik görev performanslarını karşılaştırmaları istenmiştir. Araştırma hem sadece evden hem sadece işyerinden hem de hem evde hem de işyerinde görev yapmakta olan personeli olan bir çağrı merkezi firmasında gerçekleştirilmiştir. Firmanın 260 kişiden oluşan tüm çağrı merkezi personelinin katılımıyla gerçekleştirilen çalışmada, elde edilen veriler SPSS programıyla istatistiki analizlere tabi tutulmuş, korelasyon tablosu ile ilişkiler tespit edilmiştir. Sonrasında da tek yönlü ANOVA analizi ile gruplar arası farklılaşmaların varlığı incelenmiştir. Sonuçlar göstermektedir ki COVİD-19 öncesi döneme kıyasla sadece evden çalışanlar veya haftanın belli günleri evden belli günleri işyerinden çalışanların genel görev performanslarına yönelik algıları, sadece işyerinden çalışanlara nazaran artmıştır. Bu çalışma, evden çalışmanın çalışanları olumlu yönde etkilediğini ortaya koymuştur. Ayrıca spesifik görev performansı kavramını literatüre kazandırmıştır.
Miniaturization of rectangular microstrip patch antenna using optimized single‐slotted ground plane

In this article, a new design for single‐layer rectangular microstrip patch antenna has been proposed.This design uses a ground plane with a single slot. It has been shown that by using this slotted ground plane, the resonant frequency has been lowered considerably, thus, reducing the size of the antenna. Using this design, the size of the antenna is reduced by about 90%. It has been also shown that the resonant frequency can be reduced further by increasing the length of the slot. © 2010 Wiley Periodicals, Inc. Microwave Opt Technol Lett 53:111–115, 2011; View this article online at wileyonlinelibrary.com. DOI 10.1002/mop.25661
Resonance in a superstrate-loaded rectangular microstrip structure

The complex resonant frequency of a superstrate-loaded rectangular microstrip structure is investigated. The study is performed by using a full-wave analysis and Galerkin's moment method. The numerical convergence using sinusoidal basis functions, with and without considering the edge singularity to expand the unknown surface current distribution on the rectangular patch, is discussed. Numerical results for the effects of superstrate permittivity and thickness on the complex resonant frequency of the rectangular microstrip structure are also presented. >
Flicker and thermal noise in an n-channel underlap DG FinFET in a weak inversion region

We propose an analytical model for drain current and inversion charge in the subthreshold region for an underlap DG FinFET by using the minimum channel potential method, i.e., the virtual source. The flicker and thermal noise spectral density models are also developed using these charge and current models expression. The model is validated with already published experimental results of flicker noise for DG FinFETs. For an ultrathin body, the degradation of effective mobility and variation of the scattering parameter are considered. The effect of device parameters like gate length Lg and underlap length Lun on both flicker and thermal noise spectral densities are also analyzed. Increasing Lg and Lun, increases the effective gate length, which reduces drain current, resulting in decreased flicker and thermal noise density. A decrease of flicker noise is observed for an increase of frequency, which indicates that the device can be used for wide range of frequency applications.
Fahr’s Syndrome Presenting As Pre-senile Dementia With Behavioral Abnormalities: A Rare Case Report

Fahr’s syndrome is a rare neurological disorder characterized by bilateral basal ganglia calcification. Calcification may also involve other brain areas like dentate nuclei of the cerebellum, thalamus, cerebral cortex, hippocampus, and subcortical white matter. Many cases of Fahr’s syndrome present with movement disorders, but may also present with dementia, psychiatric manifestations, and language difficulties. Fahr’s syndrome generally occurs secondary to metabolic abnormality mainly hypoparathyroidism. Fahr’s disease is another variant that is characterized by idiopathic bilateral calcification of basal ganglia in absence of any evident etiology. The present case report presented a rare case of Fahr’s syndrome secondary to hypoparathyroidism presenting with pre-senile dementia with behavioral abnormalities.
Linear phase bandpass digital filters with variable cutoff frequencies

A low-pass-to-bandpass transformation for linear phase FIR filters is discussed. The transformed bandpass filter is implemented in a network structure in which the cutoff frequencies are controlled through two parameters. The range through which the cutoff frequencies of the transformed filter can be varied depends on the cutoff frequency and the stopband edge frequency of the prototype low-pass filter. For a given prototype filter, this range is obtained from a set of simple graphs.
Fiber-Reinforced Asphalt Concrete as Sustainable Paving Material for Airfields

Sustainability at airports has received attention recently as owners have worked to incorporate sustainable practices into projects and daily operations. Several guides have been published by airport agencies to document sustainable practices. One potential practice involves alternative paving materials for airfield pavements. Specifically, fiber-reinforced asphalt concrete has shown promising results and has recently been used to resurface Runway 1–19 at the Jackson Hole Airport in Jackson, Wyoming. This paper explores the feasibility of using fiber-reinforced asphalt concrete as a sustainable paving strategy for airfields. The study includes an extensive literature review, performance testing of an asphalt mixture, cost analysis, a sustainable credit summary, and a carbon dioxide emission comparison. Laboratory testing showed that the Jackson Hole Airport mixture performed better than a control mixture produced in the laboratory with similar materials. Further analysis concluded that a fiber-reinforced, porous asphalt friction course could qualify for several sustainable site credits. In addition, the minimal upfront cost of fibers makes this product attractive because the cost can be recouped by an approximate 1-year extension in service life. Pavement design simulations indicated a reduction in equivalent carbon dioxide emissions through the extension of service life. Recommendations for the use of fiber-reinforced asphalt concrete on airfields are provided based on the findings of this study and future research is identified.
Safety and Operational Characteristics of Lane Widths on Urban and Rural Roadways A Simulator Study

ii ACKNOWLEDGEMENTS iv TABLE OF CONTENTS v LIST OF TABLES viii LIST OF FIGURES x CHAPTER 1 : INTRODUCTION 1 CHAPTER 2 : LITERATURE REVIEW 4 Lane/Shoulder Width and Road Geometry 8 Lane Keeping Studies 9 Gap Acceptance 14 Two-way Left Turn Lane 18 CHAPTER 3 : METHODOLOGY 20 Materials 21 Project Details & Layout 22 Adaptation Scenarios 28 Full Scale Study 30 Participants 30 Design 31 Procedure 35 Procedure for Data Analysis 37 Gap Acceptance 40 TWLTL 40 CHAPTER 4 : RESULTS 42 Rural Section 42 Percent Time out of Lane 42 Out of Lane Encroachments 46
Plant based removal and recovery of rare earth elements

The impact of urbanization and industrialization has accelerated the degradation of environmental components. Industrial wastewater and ore mining act as a hotspot for entry of metals, metalloids and rare earth elements (REE) to freshwater ecosystems. They are found in the form of cations, inorganic or organic complexes of humic and fulvic acid as a part of the dissolved organic matter (DOC) and also bound to the suspended solids. This necessitates the use of technologies that assist in the removal of these heavy metals, metalloids and REE. Active (such as precipitation or ion exchange) (Babel & Kurniawan, 2003) or passive (wetlands or by granulate substances) (Kropfelova et al., 2009) water filtration systems have been used successfully. Considering wetland ecosystems, which act as a sink for metals, metalloids or REE, both natural and constructed wetlands (CWs) can be employed for the above purpose. CWs mimic natural wetlands and are considered as innovative technology that can treat a wide range of pollutants, including nutrients, organic pollutants, bacteria, antibiotic resistant genes, heavy metals, metalloids and REE (Stefanakis, 2019). Wetlands have the potential to remove pollutants by complex reactions involving the plants, microbes and substrates/media along with the process of sedimentation (Davranche et al., 2016). The main benefits of nature based solutions to be employed on fields are the low construction and operational cost and low maintenance requirement. Moreover, the energy requirement is almost negligible which shows their suitability in both rural