Miracle-dz/UniFAR-FTUs huggingface dataset:
Associations of quality of life with health-related characteristics among children with autism

We examine whether behavioral, mental health, and physical health characteristics of children with autism are associated with baseline and change in health-related quality of life. We measured health-related quality of life with the Pediatric Quality of Life Inventory 4.0 total scores from children enrolled in the Autism Treatment Network. We used linear mixed model regressions with random slopes. Predictors of lower health-related quality of life at baseline included demographic and insurance characteristics, diagnosis, higher Child Behavior Checklist internalizing and externalizing scores, sleep problems by Children’s Sleep Habits Questionnaire, seizures, gastrointestinal problems, and mental health problems. Several characteristics had different associations over time. This study demonstrates that in addition to behavioral and autism-related characteristics, physical and mental health conditions are associated with health-related quality of life in children with autism.
PKU @ CLSciSumm-17: Citation Contextualization

This report gives a brief introduction of our participation in CL-SciSumm 2017 Task 1A. We demonstrate some data analysis and point out the difficulty of this task. Then we report both unsupervised and supervised methods with their performances on 2016 and 2017 testset, from which efficiency of different features can be estimated.
Low Cost Compact Multiband Printed Monopole Antennas and Arrays for Wireless Communications

It is well-known that the size reduction will decrease the radiation efficiency of the antenna especially when its size is very small compared to the free space wavelength at its lowest resonant frequency. Conventional high permittivity substrates can be employed to reduce the size of the microstrip antenna (e.g. printed microstrip patch) but raises other design issues. When using this approach the bandwidth of the antenna is decreased and the surface wave propagations are excited, which can lead to the scan blindness if a beam-steerable phased array is built based on this antenna element. Therefore, it is important to investi‐ gate techniques for the design of compact and low cost microstrip antennas with promis‐ ing radiation characteristics.
Joint Selection with Multi-Streams for Multiuser MIMO Systems with Block Diagonalization

In this paper, we present a new scheme combining mode switching (SM/STBC), and transmit antenna subset selection (Tx-AnSS), i.e.,joint selection for a multiuser-MIMO (MU-MIMO) system with block diagonalization (BD) for error probability enhancement. Further, the proposed scheme also adaptively selects the number of streams by a simple selection criterion which is a square minimum Euclidean distance of the user with worst performance. Then, the proposed joint selection with multi-streams can take the advantages of spatial diversity improvement and array gain. Simulation results show that bit error rate (BER) of the proposed scheme outperforms the conventional schemes, which follows the SM-based scheme at low-SNR region and the STBC-based scheme at high-SNR region.
Prevalence of HIV infection in psychiatric patients attending a general hospital in Tamil Nadu, South India

An anonymous, unlinked study was conducted to detect antibodies to HIV-1 or HIV-2 infections in 1,160 consecutive, newly registered, adult psychiatric outpatients at a general hospital in South India to determine whether psychiatric patients presenting to general hospitals are a population at high risk for HIV infection and should be routinely screened. The seroprevalence of HIV infection (12/1160; 1.03%; 95% CI=0.4-1.6%) did not approximate rates expected of a high-risk group compared to the national (0.7%) or regional community (1.8%) prevalence. It did not differ significantly from HIV seroprevalence in non-psychiatric patients (233/35450; 0.7%; 95% CI=0.57-0.74%) who were systematically screened (relative risk=1.57; 95% CI=0.88-2.80) during the same period, but was greater than the seroprevalence in healthy blood donors (0.5%; p=0.02; relative risk=2.15 95% CI=1.17-3.95). Non-psychiatric patients were also more likely to be HIV infected than blood donors (p=0.02; relative risk=1.37; 95% CI=1.05-1.78). These findings have implications for HIV testing policies among psychiatric and non-psychiatric patients presenting to general hospitals in India.
Effect of N-terminal α-Helix Formation on the Dimerization and Intracellular Targeting of Alanine:Glyoxylate Aminotransferase*

The unparalleled peroxisome-to-mitochondrion mistargeting of alanine:glyoxylate aminotransferase (AGT) in the hereditary disease primary hyperoxaluria type 1 is caused by the combined presence of a common Pro11 → Leu polymorphism and a disease-specific Gly170 → Arg mutation. The Pro11 → Leu replacement generates a functionally weak N-terminal mitochondrial targeting sequence (MTS), the efficiency of which is increased by the additional presence of the Gly170 → Arg replacement. AGT dimerization is inhibited in the combined presence of both replacements but not when each is present separately. In this paper we have attempted to identify the structural determinants of AGT dimerization and mitochondrial mistargeting. Unlike most MTSs, the polymorphic MTS of AGT has little tendency to adopt an α-helical conformationin vitro. Nevertheless, it is able to target efficiently a monomeric green fluorescent (GFP) fusion protein, but not dimeric AGT, to mitochondria in transfected COS-1 cells. Increasing the propensity of this MTS to fold into an α-helix, by making a double Pro11 → Leu + Pro10 → Leu replacement, enabled it to target both GFP and AGT efficiently to mitochondria. The double Pro11 → Leu + Pro10 → Leu replacement retarded AGT dimerization in vitro as did the disease-causing double Pro11 → Leu + Gly170→ Arg replacement. These data suggest that N-terminal α-helix formation is more important for maintaining AGT in a conformation (i.e. monomeric) compatible with mitochondrial import than it is for the provision of mitochondrial targeting information. The parallel effects of the Pro10 → Leu and Gly170 → Arg replacements on the dimerization and intracellular targeting of polymorphic AGT (containing the Pro11 → Leu replacement) raise the possibility that they might achieve their effects by the same mechanism.
Fault detection for nonlinear non-affine systems via sliding-mode output-feedback and HOSM differentiator

This paper deals with the fault detection problem for nonlinear uncertain non-affine systems. The variable-structure output-feedback stabilization based on observer is required. Depending on the type of uncertainties, conditions are given under which convergence to the unique solution of both the system and the observer, and fault detection are achieved. Simulation results illustrate the feasibility of the proposed approach.
ISOLATED WORD RECOGNITION SYSTEM FOR SPEECH TO TEXT CONVERSION USING ANN

The capacity of a device or a program to listen, identify various sounds is referred as Speech recognition and recognize some known languages from the spoken words and for human machine interface the Automatic Speech Recognition (ASR) system is helpful. In recent periods, for the ASR system, lot of research works has been developed but the concerns in that system arevast, because of the improper techniques used for the feature selection. Proper features are selected in this paper in order to develop a superior ASR system and convert the spoken word into corresponding text. Three phases are comprised in the proposed system; preprocessing, feature extraction and classification. Initially, from the source the spoken word is detected by the preprocessing phase and the noise level is reduced. Then, totally eight features are extracted containing five statistical features and three common in the feature extraction phase. Then, the classifier is trained by using these features referred as artificial neural network (ANN) with back propagation (BP). The eight features are use as the training dataset for BP algorithm and based on this feature the corresponding text displayed at the output of the proposed ASR system. The proposed system is implemented in the working platform of MATLAB. The implementation result prove that the system provide superior classification and converts the text properly. The classification accuracy examined based on performance metrics. Ultimately, the overall performance of the proposed ASR system is superior and well suitable for human machine interface.
Study of the atmospheric wake turbulence of a CFD actuator disc model

Modelling wind turbine wake using the standard k − ǫ atmospheric turbulence model gives a too fast wake dissipation compared to measurements and more advanced turbulence models. The problem is that the relevant scales of turbulence are diﬀerent from the point of view of the wind turbines and from the point of view of the terrain. As the atmospheric turbulence model imposes the scale of turbulence, part of the inﬂuence of the wind turbine on the airﬂow is happening at the turbulence level. It becomes therefore necessary to add terms in the turbulence equations to account for the wind turbine activity. In this context two dif-ferent models are compared together and with wind turbine wake measurements. With the proper parameterization, they are both able to produce similar results, in agreement with the measurements.
An analysis of EEG signals during voluntary rhythmic foot movements

Human locomotion is based on complex interactions of several cortical and subcortical structures. Over the years, the main underlying mechanisms have been partially unveiled thanks to standard functional neuroimaging techniques as well as electroencephalography (EEG). However, a complete picture is still lacking to date, due to particularly challenging experimental difficulties arising on top of the inherent complexity of the involved mechanisms. In this context, the aim of this study was to investigate the EEG dynamics associated to the production of voluntary rhythmic foot movements only. We used an experimental protocol limiting drastically the presence of movement artifacts in the EEG signals compared to real walk on a treadmill. A time-frequency analysis was performed, based on a time-warping method allowing an ensemble averaging of the data of 3 subjects. Characteristic alternation of power increases and decreases in the alpha, beta and gamma bands during the movement cycle is demonstrated as well as the emergence of two different neural coordination schemes related to in-phase and anti-phase foot movements.
Mental and physical well-being in oncology-hematology–unit personnel

ABSTRACT Health care workers (HCWs) in university hematology units (UHUs) face high job demand that can have adverse health effects. This cross-sectional study investigated the relationship between some job stressors and health-related quality of life among HCWs of 3 UHUs in Rome. Work-related stress was measured with the Demand–Control Questionnaire; health-related functioning with the mental component score (MCS) and physical component score (PCS) of the Short Form 12 Survey; positivity with the Positivity Scale. Data of 201 respondents were analyzed. Job demand was inversely associated with MCS (p = .05) and PCS (p = .049); job control was directly associated with PCS (p < .001) and MCS (p = .024). A high positivity scale score and high decision latitude score predicted high MCS and PCS. High job demand score predicted low MCS and PCS scores. Reduced job stressors and enhanced positive attitudes can improve HCWs’ health-related quality of life.
Small signal model load flow initialisation for converter-dominated microgrids

In this paper, a load flow initialisation method is proposed to calculate the steady-state initial conditions required for small signal stability analysis of a converter-dominated microgrid. The proposed load flow simulation eliminates the need to run a flat start time-domain analysis in order to arrive at the initial values and therefore allows for the rapid small signal analysis of different network topologies and parameters. The proposed method is validated by identifying the critically stable operating points of a test network using eigenvalue analysis and then verifying the stability behaviour of these operating points with time-domain simulations. Using the developed techniques, a network sensitivity analysis is also performed to examine the effects of network parameters on system stability.
A Survey on Return-Oriented Programming

The focus of this research is studying Return-Oriented Programming (ROP), which is a technique for exploiting software vulnerabilities. The reasons and motivations behind proposing ROP, the mechanism of working, automation tools, detection and prevention methods and new advances in ROP attacks are some of the important topics covered in this report.
IMPROVING CLASSIFICATION PERFORMANCE OF K-NEAREST NEIGHBOUR BY HYBRID CLUSTERING AND FEATURE SELECTION FOR NON-COMMUNICABLE DISEASE PREDICTION

Non-communicable Disease (NCDs) is the high mortality rate in worldwide likely diabetes mellitus, cardiovascular diseases, liver and cancers. NCDs prediction model have problems such as redundancy data, missing data, noisy class and irrelevant attribute. This paper proposes a novel NCDs prediction model to improve accuracy. Our model comprises k-means as clustering technique, Weight by SVM as feature selection technique and k-nearest neighbour as classifier technique. The result shows that k-means + weight by SVM + k-nn improved the classification accuracy on most of all NCDs dataset (accuracy; AUC), likely Pima Indian Dataset (96.82; 0.982), Breast Cancer Diagnosis Dataset (97.36; 0.997), Breast Cancer Biopsy Dataset (96.85; 0.994), Colon Cancer (99.41; 1.000), ECG (97.80; 1.000), Liver Disorder (97.97; 0.998).
An Undecaprenyl Phosphate-Aminoarabinose Flippase Required for Polymyxin Resistance in Escherichia coli*

Modification of lipid A with the 4-amino-4-deoxy-l-arabinose (l-Ara4N) moiety is required for resistance to polymyxin and cationic antimicrobial peptides in Escherichia coli and Salmonella typhimurium. An operon of seven genes (designated pmrHFIJKLM in S. typhimurium), which is regulated by the PmrA transcription factor and is also present in E. coli, is necessary for the maintenance of polymyxin resistance. We previously elucidated the roles of pmrHFIJK in the biosynthesis and attachment of l-Ara4N to lipid A and renamed these genes arn-BCADT, respectively. We now propose functions for the last two genes of the operon, pmrL and pmrM. Chromosomal inactivation of each of these genes in an E. coli pmrAc parent switched its phenotype from polymyxin-resistant to polymyxin-sensitive. Lipid A was no longer modified with l-Ara4N, even though the levels of the lipid-linked donor of the l-Ara4N moiety, undecaprenyl phosphate-α-l-Ara4N, were not reduced in the mutants. However, the undecaprenyl phosphate-α-l-Ara4N present in the mutants was less concentrated on the periplasmic surface of the inner membrane, as judged by 4-5-fold reduced labeling with the inner membrane-impermeable amine reagent N-hydroxysulfosuccin-imidobiotin. In an arnT mutant of the same pmrAc parent, which lacks the enzyme that transfers the l-Ara4N unit to lipid A but retains the same high levels of undecaprenyl phosphate-α-l-Ara4N as the parent, N-hydroxysulfosuccinimidobiotin labeling was not reduced. These results implicate pmrL and pmrM, but not arnT, in transporting undecaprenyl phosphate-α-l-Ara4N across the inner membrane. PmrM and PmrL, now renamed ArnE and ArnF because of their involvement in l-Ara4N modification of lipid A, may be subunits of an undecaprenyl phosphate-α-l-Ara4N flippase.
Colored medaka and zebrafish: Transgenics with ubiquitous and strong transgene expression driven by the medaka β‐actin promoter

Conditional cell labeling, cell tracing, and genetic manipulation approaches are becoming increasingly important in developmental and regenerative biology. Such approaches in zebrafish research are hampered by the lack of an ubiquitous transgene driver element that is active at all developmental stages. Here, we report the isolation and characterization of the medaka fish (Oryzias latipes) β‐actin (Olactb) promoter, which drives constitutive transgene expression during all developmental stages, and the analysis of adult organs except blood cell types. Taking advantage of the compact medaka promoter, we succeeded in generating a zebrafish transgenic (Tg) line with unprecedentedly strong and widespread transgene expression from embryonic to adult stages. Moreover, the Tg carries a pair of loxP sites, which enables the reporter fluorophore to switch from DsRed2 to enhanced green fluorescent protein (EGFP). We induced Cre/loxP recombination with Tg(hsp70l: mCherry‐t2a‐CreERt2) in the double Tg embryo and generated a Tg line that constitutively expresses EGFP. We further demonstrate the powerful application of Olactb‐driven Tgs for cell lineage tracing using transplantation experiments with embryonic cells at the shield stage and adult cells of regenerating fin. Thus, the use of promoter elements from medaka is an alternative approach to generate Tgs with stronger and even novel expression patterns in zebrafish. The Olactb promoter and the Tg lines presented here represent an important advancement for the broader use of Cre/loxP‐based Tg applications in zebrafish.
Comparing Performance of Nonlinear Complexity Metrics for Assessing Quality of ECGs Collected in Real Time

We compared performance of a novel encoding Lempel-Ziv complexity (ELZC) with 10 approximate entropy (ApEn), sample entropy (SmpEn) and permutation entropy (PerEn) as 11 nonlinear metric to assess ECG quality. Firstly to compare performance of discerning randomness 12 and inherent nonlinear properties within time series, this study calculated the aforementioned 13 four nonlinear complexity values on several typical artificial time series i.e., Gauss noise, two 14 kinds of noisy time series, two kinds of Logistic series and periodic series, respectively. Then for 15 analyzing sensitivity of the aforementioned four complexity methods to content level of different 16 types noise within ECG recordings, we investigated variation trend of ELZC, ApEn, SmpEn and 17 PerEn in several synthetic ECG recordings containing different types noise (i.e., baseline wander, 18 muscle artefacts, electrode motion, power line and mixed noise) and different signal noise ratios 19 (i.e., 15, 10, 5, 0, −5 and −10 dB). Finally, the four complexity methods were employed to classify 20 the quality of real ECG recordings from the PhysioNet/Computing in Cardiology Challenge 2011 21 (CINC 2011) of the MIT databases, then receiver operating characteristic curves (ROC) and their 22 corresponding area under curve (AUC) were yielded. The results showed ELZC could not only 23 distinguish randomness and chaotic within time series but also reflect content level of noise within 24 time series, and the highest AUC of PerEn, ELZC, SmpEn and ApEn were 0.850, 0.695, 0.474 and 25 0.461, respectively. The results demonstrated PerEn and ELZC were more effectively than ApEn 26 and SmpEn for assessing ECG quality. 27
Patented Technologies in Fast Dissolving Tablets: A Review

Improvement of patient’s compliance has always a challenge towards the development of oral drug delivery system. Different dosage forms are available in the market among all oral dosage form is preferred one. However, the incompliance of pediatric & geriatric patients the scientists worked towards fast dissolving solid dosage form to encounter existing drawbacks with unique palatability and rapid disintegration. The concept of fast dissolving tablet came into existence in late 1970s. Recently, fast dissolving drug delivery systems have started gaining popularity and acceptance as new drug delivery system, because they are easy to administer and lead to better patient compliance. For further improvement in existing technologies and newer technologies has been succeeded and still research is going on in improvement with its preparation methodologies all over the globe. Fast dissolution tablets have faster disintegration and dissolution rate and release within 30 seconds as they come in contact with saliva. These systems also obviate the requirement of carry water during drug administration. As fast dissolving tablets falls under desired expectation of safer, convenient and economical solid dosage forms, several techniques have been developed to improve disintegration quality in the recent past years. This article mainly focuses on patented technologies with recent advancement made so far in the field of the fast dissolving tablets.
Protective role of diets containing Gongronema latifolium leaves on Streptozotocin- induced oxidative stress and liver damage

Article history: Received on: 07/12/2014 Revised on: 11/01/2015 Accepted on: 29/01/2015 Available online: 28/03/2015 This study was aimed at determining some biomarkers of oxidative stress and liver damage in diabetic rats consuming diets containing Gongronema latifolium leaves so as to evaluate the involvement of the diets in the management of oxidative stress and liver damage common among diabetics. Fifty rats were randomly divided into five groups (1 to 5) with10 rats per group. Group 1 (normal control) consumed control diet; Group 2 (diabetic control) consumed control diet, Group 3 and 4 (diabetic treated) consumed Gongronema latifolium at 5% and 7.5%, respectively. Group 5 (diabetic treated) consumed control diet and was treated with Insulin. Feed and water were given adlibitum for 28 days. Results showed that diabetic rats in groups 3 and 4 consuming Gongronema latifolium had significant (P<0.05) reduction in MDA concentration and in the level of ALT, AST, and ALP in the serum and liver tissue homogenate and a significant increase it the activities of GPx, SOD and Catalase relative to the diabetic control. The results were superior to those on Insulin. It was concluded that consumption of diets containing Gongronema latifolium leaves has protective effect on oxidative stress and liver damage associated with diabetes mellitus.
Personal Outcomes and Moral Responsibility as Motives for News Transmission

In two experiments we compared contrasting findings on bad news transmission likelihood between literature on rumors and the MUM-effect in order to contribute to the development of a more general theory of news transmission. We argued that several contextual differences account for the contrasting findings between these research conditions. We predicted that fate similarity and fate uncertainty (both present in many rumor contexts and absent in most MUM-contexts) enhance the anticipated personal outcomes of bad news transmission for communicators and hence increase bad news transmission. Supporting our argument, we found that fate uncertainty and fate similarity each increased the likelihood of bad news transmission up to the level of good news transmission. Furthermore, these effects were mediated by communicators’ anticipated personal outcomes of transmission. In addition, Experiment 2 demonstrated anticipated personal outcomes to be only an important motive for news transmission decisions in superficial relationships; for close relationships, experienced moral responsibility appeared to be the paramount motive for transmission.