Miracle-dz/UniFAR-FTUs huggingface dataset:
Title Clinical characteristics of patients with anti-aminoacyl-tRNA synthetaseantibody positive idiopathic interstitial pneumonia

Background: Anti-aminoacyl-tRNA synthetase (ARS) antibodies have been detected in patients with polymyositis/dermatomyositis (PM/DM) and are especially correlated with interstitial lung disease (ILD). The aim of this study was to clarify the clinical features of patients with anti-ARS antibody positive idiopathic interstitial pneumonias (IIPs). Methods: Patients were classified into three groups: 1) IIP with anti-ARS antibodies (ARS(+)IIP), 2) IIP without anti-ARS antibodies (ARS(−)IIP), and 3) PM/DM-associated ILD with anti-ARS antibodies (ARS(+)PM/DMILD). Clinical characteristics were compared retrospectively between the ARS(+)IIP group and the ARS(−)IIP group or ARS(+)PM/DM-ILD group. Results: Eighteen ARS(+)IIP, 284 ARS(−)IIP, and 20 ARS(+)PM/DM-ILD patients were enrolled. The ARS(+) IIP group was significantly older and the male sex was predominant, had a lower prevalence of signs of connective tissue disease, differences in HRCT findings and patterns, and higher KL-6 levels compared to the ARS (+)PM/DM-ILD group. The findings in the bronchoalveolar lavage fluid (BALF) showing lymphocytosis and a lower CD4/CD8 ratio were similar between the two groups. However, the ARS(+)IIP group had significantly lower percentage of sputum, higher prevalence of mechanic's hand, higher KL-6 levels, lower percentage of vital capacity in the pulmonary function test, and lower CD4/CD8 ratio in BALF, compared to the ARS(−)IIP group. Conclusions: The present study demonstrated that features of pulmonary involvement were similar to those in the ARS(+)PM/DM-ILD group; however, some differences including HRCT findings and higher KL-6 levels suggest that ARS(+)IIP has severe ILD compared with ARS(+)PM/DM-ILD. Further prospective studies with a larger number of patients will elucidate the exact role of anti-ARS antibodies in IIPs. http://dx.doi. org/10.1016/j.rmed. 2017.10. 020 Received 26 June 2017; Received in revised form 25 October 2017; Accepted 25 October 2017 ∗ Corresponding author. E-mail address: nsakamot@nagasaki-u.ac. jp (N. Sakamoto). Abbreviations: ALD, aldolase; ARS, anti-aminoacyl-tRNA synthetase; ARS(−), anti-ARS antibody negative; ARS(+), anti-ARS antibody positive; ASS, anti-synthetase syndrome; BALF, bronchoalveolar lavage fluid; CADM, clinically amyopathic dermatomyositis; CK, creatine kinase; CT, computed tomography; CTD, connective tissue diseases; DAD, diffuse alveolar damage; HRCT, high-resolution computed tomography; IIP, idiopathic interstitial pneumonia; ILD, interstitial lung disease; IPF, idiopathic pulmonary fibrosis; KL-6, Krebs von den Lungen 6; NSIP, nonspecific interstitial pneumonia; OP, organizing pneumonia; PM/DM, polymyositis/dermatomyositis; UIP, usual interstitial pneumonia; %VC, percentage of the vital capacity Respiratory Medicine 132 (2017) 189–194 Available online 28 October 2017 0954-6111/ © 2017 Elsevier Ltd. All rights reserved. T
Anomalous secular sea-level acceleration in the Baltic Sea caused by isostatic adjustment

Observations from the global array of tide gauges show that global sea-level has been rising at an average rate of 1.5-2 mm/yr during the last ~150 years [Douglas 1991, Spada and Galassi 2012]. Although a global sea-level acceleration was initially ruled out [Douglas 1992], subsequent studies [Douglas 1997, Church and White 2006, Jevrejeva et al. 2008, Church and White 2011] have coherently proposed values of ~1 mm/year/century [Olivieri and Spada 2013]. More complex non-linear trends and abrupt sea-level variations have now also been recognized. Globally, these could manifest a regime shift between the late Holocene and the current rhythms of sea-level rise [Gehrels and Woodworth 2013], while locally they result from ocean circulation anomalies, steric effects and wind stress [Bromirski et al. 2011, Merrifield 2011]. Although isostatic readjustment affects the local rates of secular sea-level change [Milne and Mitrovica 1998, Peltier 2004], a possible impact on regional acceleration has been so far discounted [Douglas 1992, Jevrejeva et al. 2008, Woodworth et al. 2009] since the process evolves on a millennium time scale [Turcotte and Schubert 2002]. Here we report a previously unnoticed anomaly in the long-term sea-level acceleration of the Baltic Sea tide gauge records, and we explain it by the classical post-glacial rebound theory and numerical modeling of glacial isostasy. Contrary to previous assumptions, our findings demonstrate that isostatic compensation plays a role in the regional secular sea-level acceleration.
Preparing for Complexity and Wicked Problems through Transformational Learning Approaches

As the information environment becomes increasingly complex and challenging, Library and Information Studies (LIS) education is called upon to nurture innovative leaders capable of managing complex situations and “wicked problems. ” While disciplinary expertise remains essential, higher levels of mental complexity and adaptive capabilities are also needed to manage complexity. This article reviews three transformational learning approaches with the potential to effectively guide student growth toward these higher levels: (1) overcoming immunity to change, (2) threshold concepts and variation theories, and (3) transformative learning theory. All three approaches aim at transforming high-level meanings that are limiting into understandings that empower in order to achieve pragmatic goals, comprehend foundational disciplinary concepts, and generate new frames of reference for social justice.
Towards a public, standardized, diagnostic benchmarking system for land surface models

Abstract. This work examines different conceptions of land surface model benchmarking and the importance of internationally standardized evaluation experiments that specify data sets, variables, metrics and model resolutions. It additionally demonstrates how essential the definition of a priori expectations of model performance can be, based on the complexity of a model and the amount of information being provided to it, and gives an example of how these expectations might be quantified. Finally, the Protocol for the Analysis of Land Surface models (PALS) is introduced – a free, online land surface model benchmarking application that is structured to meet both of these goals.
A model for mapping of Ebola and Marburg RNA integration sites in rhesus Macaca mulatta genome in silico: Ebola virus acceptors sites located on chromosomes 4, 6, 7, 8, 9, 14 and 15.

Viral integration into the host genetic material is necessary for replication and survival, since viruses are obligate intracellular organisms. Understanding of the exact loci of integration may thus provide targets for future therapeutic and vaccine strategies, pathogenesis elucidation, as well as a model for the evolutionary trends of successful viral cross over. Although the exact natural reservoir for the filovirade family of viruses still remains elusive, most index cases in human outbreaks have been linked to contact with nonhuman primates (NHP). We hypothesized that homogeneity between viral integration complex and host genome may be a major predictor of integration. To investigate and map the loci of integration of the two major genes of this family of viruses within NHP genomes, we queried both Ebola and Marburg Glycoprotein (GP) gene sequences against the whole genome of rhesus macaque using BLAST-N analysis. Of all the contigs length 2.87 Gb (2,863,665,185) bases in the genome of rhesus macaque, Marburg GP blast hits to rhesus genome nucleotide database were 6,451,736 compared to 4,012,901 for Ebola. Marburg GP genomic RNA had 18 alignments located on undefined scaffolds compared to 7 of Ebola located on chromosomes 4, 6, 7, 8, 9, 14 and 15. We also found an efficiency of 66.6% within Marburg GP alignments compared to 100% for Ebola. Our results serve to demonstrate that although Marburg GP RNA acceptors are more prevalent in the Rhesus genome than ebola; their loci of integration are vaguely defined compared to Ebola. If the level of homogeneity between acceptors and PIC has no effect of integration, then Marburg may be better adapted to integrate into Rhesus that Ebola. Alternatively, chromatic DNA might be a more effective target for future Ebola genomic vaccines sequestered at a nuclear location inaccessible to incoming Pre-integration Complexes (PICs-which in this model are Ebola glycoprotein gene complexes) than Marburg.
Culture Practice of Thai Koi (Anabas Testudineus) With Different Stocking Densities at Tarakanda in Mymensingh District

The present experiment was conducted to study the culture practice of Thai Koi ( Anabas testudineus) with different stocking densities and their growth performance. The study was carried out over a period of 76 days from 22 June, 2008 to 05 September, 2008 in Tarakanda upazila of Mymensingh district. For the study, the experiment was undertaken with 3 treatments (T 1 , T 2 and T 3 ) each having two replications (R 1 and R 2 ). Three different stocking densities designed as treatments viz., 550 in T 1 , 400 in T 2 and 350 fry /dec in T 3 . The fry of same size (length 2.45 cm and weight 5g initially) were stocked and they were fed with commercial pelleted feed according to their body weight. At the very beginning 16% feed were provided with frequency 4 times in a day. It was decrease up to 4.5% before 10 days of harvesting. During the experiment period, water quality was assessed fortnightly. The average temperature was found 28.21±0.870, 28.78±0.510 and 28.76±0.78 0 C in treatments T 1 , T 2 and T 3 respectively. The pH ranges were varied between 7.70 to 9.10 among the three treatments. The mean values of dissolve oxygen were 5.33±0.34, 4.23±0.13, 4.16±0.14 mg/L respectively in the three consecutive treatments. The growth performance was determined by measuring length (cm) and weight (g). Treatment-3 where stocking density was less showed the best growth performance followed by T 1 and T 2 . The production was higher 8719.10kg/ha in T 1 was obtained from this treatment. DOI: http://dx.doi. org/10.3329/jesnr.v6i2. 22116 J. Environ. Sci. & Natural Resources, 6(2): 191-196 2013
Does hedging lead to value increase among non-financial firms in Netherlands?

The topic of this thesis concerns the effect of hedging with foreign currency derivatives on firm value of 93 Dutch firms that publicly listed non-financial in 2012. For this purpose, Firm value is measured by Tobin’s Q, a hedging dummy variable is as a proxy for foreign currency derivatives and other control variables that can affect firm value are considered as well. Then a linear regression is performed on the data to investigate the impact of hedging with FCD on firm value. The results from my research show that hedging with FCD may decrease the firm value.
Extraction of Information of Audio-Visual Contents

In this article we show how it is possible to use Channel Theory (Barwise and Seligman, 1997) for modeling the process of information extraction realized by audiences of audio-visual contents. To do this, we rely on the concepts pro- posed by Channel Theory and, especially, its treatment of representational systems. We then show how the information that an agent is capable of extracting from the content depends on the number of channels he is able to establish between the content and the set of classifications he is able to discriminate. The agent can endeavor the extraction of information through these channels from the totality of content; however, we discuss the advantages of extracting from its constituents in order to obtain a greater number of informational items that represent it. After showing how the extraction process is endeavored for each channel, we propose a method of representation of all the informative values an agent can obtain from a content using a matrix constituted by the channels the agent is able to establish on the content (source classifications), and the ones he can understand as individual (destination classifications). We finally show how this representation allows reflecting the evolution of the informative items through the evolution of audio-visual content.
On the Surface Fields of a Small Circular Loop Antenna Placed on Plane Stratified Earth

An analytical method is presented which makes it possible to derive exact explicit expressions for the time-harmonic surface fields excited by a small circular loop antenna placed on the top surface of plane layered earth. The developed procedure leads to casting the complete integral representations for the EM field components into forms suitable for application of Cauchy’s integral formula. As a result, the surface fields are expressed as sums of Hankel functions. Numerical simulations are performed to show the validity and accuracy of the proposed solution.
Video Micro Analysis – from a qualitative approach

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Marker assisted selection for S5 neutral allele in inter-subspecific hybridization of rice

The present level of heterosis in indica hybrids can be improved by exploiting inter-subspecific gene pool. Hybrid sterility in inter-subspecific hybridization is the major bottleneck, however use ofwide compatible varieties (WCVs) carrying neutral alleles helps in producing fertile hybrids. Conventionally WC varieties are identified by tedious test crossing. To identify WC varieties, 325 tropical japonica and 7 indica lines have been genotyped for the presence of S5 n (neutral allele) with the help of S5-MMS (multiplex marker system) which clearly distinguish indica, japonica and S5 neutral allele. Of the 325 lines, 90 tropical japonica and Swarna ( indica ) showed the presence of S5 n . One hundred and fifty F 1 hybrids, indica × japonica (I × J), were evaluated for their hybrid sterility and spikelet fertility percentage ranged from 4 to 97%. The I × J hybrids with S5n showed higher spikelet fertility; however some hybrids without S5 n showed higher spikelet fertility and among them few tropical japonica lines identified to carry indica allele by S5-MMS marker system, therefore this functional marker is a powerful tool for molecular screening of WC varieties. Hybrids with S5 n showed higher sterility indicating existence of other than embryo sac sterility mechanism of I X J crosses, since S5 n overcomes only embryo sac hybrid sterility. In wild rice O.rufipogon accessions the S5 n allelic status was determined by using S5-MMS marker system. To conclude, S5-MMS is a powerful tool PCR based and with low cost, highly efficient as marker system in identifying WC varieties in different mapping populations including wild rice accessions. Whichsaves one year of breeder’s valuable time in inter-subspecific hybridization in rice.
Enhancing Foreign Direct Investment via Transparency? Evaluating the Effects of the EITI on FDI

The so called resource curse, the fact that countries rich in natural resources often show lower rates of economic growth compared to resource-poor countries, is commonly attributed to the low quality of governance in resource-rich countries. The Extractive Industries Transparency Initiative (EITI) was founded in 2003 to address this problem through increasing the quality of the public financial management of resource flows. By joining this initiative, governments show their willingness to reform and to improve their governance. As the quality of governance is an important factor for investors in deciding where to invest, this signal has the potential to improve a country’s appeal for foreign direct investment (FDI). This study shows in a panel of 81 countries that joining the EITI increases the ratio of FDI inflows to GDP on average by around two percentage points. This is a remarkable increase given that the average ratio of FDI inflows to GDP in the sample is five percent. The results are robust when controlling for selection bias due to the voluntary decision to join the initiative and possible endogeneity of the candidate variable.
A test of Allen’s rule in subterranean mammals: the genus Ctenomys (Caviomorpha, Ctenomyidae)

Abstract We tested the applicability of Allen’s rule in 47 species and 32 unnamed forms (populations that are probably good species or undefined taxa within a superspecies or species group) of the South American subterranean Hystricomorph rodents of the genus Ctenomys (tuco-tucos) (Rodentia: Ctenomyidae) by analyzing tail length in relation with head and body length, and body mass. Tail length allometry was analyzed by Reduced Major Axis regression while the possible correlation of relative tail length with temperature, precipitation and evapotranspiration variables was explored through Simultaneous Autoregression to account for spatial autocorrelations. Our results indicate that tuco-tucos do not follow Allen’s rule but its converse, tail proportion relative to body mass increasing with latitude while body size decreases in the same direction (the trend is similar for tail length relative to head and body length but not statistically significant). Regarding climatic variables, the main predictors of relative tail length were temperature and evapotranspiration variables with trends confirming the positive (non-Allenian) correlation of relative tail length with latitude. We conclude that tuco-tucos, being almost fully subterranean, thermoregulate behaviorally by maintaining constant temperatures within their burrows independent of geographic location. The former confirms previous results that indicated that Ctenomys follows the converse to Bergmann’s rule. Relative tail length variation would be a result of simple allometric growth.
The Implementation of School-Based Management to Improve the Quality of Education in Laboratory Schools

This study aims to describe the assessment of the results of the implementation of school-based management in laboratory schools with reference to the components of curriculum and instruction, students, educators and staffs, finance, infrastructure, school and community relations, and the school culture and environment. This study uses a quantitative approach that is broadly divided into two, namely Experimental Research (NonExperimental Research) and Non-Experimental Research. This research includes non-experimental research with descriptive research design types. Descriptive design is intended to describe or explain the degree of implementation of school-based management in laboratory schools to improve the quality of education. The results of this study are as follows: (1) implementation of curriculum management and instruction quality in laboratory schools is very high; (2) the implementation of management of student’s quality in laboratory schools is very high; (3) implementation of management of educators and staff’s quality in laboratory schools is high; (4) implementation of finance management quality in laboratory schools is very high; (5) implementation of infrastructure facilities management quality in laboratory schools is high; (6) implementation of school and community relationship management in laboratory schools is in medium quality; and (7) implementation of school culture and environmental management quality in laboratory schools is high.
THE COGNITIVE STRUCTURE OF PRE-SERVICE SCIENCE TEACHERS ABOUT ENERGY METABOLISM

In this research word association test was used to explore the cognitive structure of Pre-service science teachers about biological energy metabolism. The participant group constitutes 67 Pre-service students at a university in Black Sea Region of Turkey. Ten key concepts in General Biology course were given as a stimulating word and a mind map was established by using the frequency values of valid response words. The results showed that the total number of different response words for the key word “enzyme” is the highest with “cell” and “energy” being higher than others and for the key word “photosynthesis” is the lowest. The mind map also showed that they based their cognitive perceptions of the biological energy mechanism mostly on scientific concepts that are emphasized in the lessons and are academically acknowledged and included in the concepts used in everyday life at the least. However, they were not able to see the key concept “enzymes” as a part of branched network and they had also problems regarding the respiratory event in the plants as well as realization process of photosynthesis in the cellular level. Implications of the results in terms of understanding the subject of biological energy metabolism are also discussed. Keywords: biological energy metabolism, cognitive structure, mind map, pre-service science teacher, word association test.
The application of satellite remote sensing for assessing productivity in relation to fisheries yields of the world's large marine ecosystems

Sherman, K. , O'Reilly, J., Belkin, I. M. , Melrose, C. , and Friedland, K. D. 2011. The application of satellite remote sensing for assessing productivity in relation to fisheries yields of the world's large marine ecosystems. – ICES Journal of Marine Science, 68: 667–676.In 1992, world leaders at the historical UN Conference on Environment and Development (UNCED) recognized that the exploitation of resources in coastal oceans was becoming increasingly unsustainable, resulting in an international effort to assess, recover, and manage goods and services of large marine ecosystems (LMEs). More than $3 billion in support to 110 economically developing nations have been dedicated to operationalizing a five-module approach supporting LME assessment and management practices. An important component of this effort focuses on the effects of climate change on fisheries biomass yields of LMEs, using satellite remote sensing and in situ sampling of key indicators of changing ecological conditions. Warming appears to be reducing primary productivity in the lower latitudes, where stratification of the water column has intensified. Fishery biomass yields in the Subpolar LMEs of the Northeast Atlantic are also increasing as zooplankton levels increase with warming. During the current period of climate warming, it is especially important for space agency programmes in Asia, Europe, and the United States to continue to provide satellite-borne radiometry data to the global networks of LME assessment scientists.
Mobility and quantum mobility of modern GaAs/AlGaAs heterostructures

In modern GaAs/Al$_x$Ga$_{1-x}$As heterostructures with record high mobilities, a two-dimensional electron gas (2DEG) in a quantum well is provided by two remote donor $\delta$-layers placed on both sides of the well. Each $\delta$-layer is located within a narrow GaAs well, flanked by narrow AlAs layers which capture excess electrons from donors. We show that each excess electron is localized in a compact dipole atom with the nearest donor. Nevertheless, excess electrons screen both the remote donors and background impurities located beyond the half of the Al$_x$Ga$_{1-x}$As barriers adjacent to the 2DEG. When the fraction of remote donors filled by excess electrons $f$ is small, the remote donor limited quantum mobility grows as $f^{3}$ and becomes larger than the background impurity limited one at a characteristic value $f_c$. We also calculate both the mobility and the quantum mobility limited by the screened background impurities with concentrations $N_1$ in Al$_x$Ga$_{1-x}$As and $N_2$ in GaAs, which allows one to estimate $N_1$ and $N_2$ from the measured mobilities. Taken together, our findings should help to identify avenues for further improvement of modern heterostructures.