Miracle-dz/UniFAR-FTUs huggingface dataset:
Validation of Serum Biomarkers That Complement CA19-9 in Detecting Early Pancreatic Cancer Using Electrochemiluminescent-Based Multiplex Immunoassays

Pancreatic ductal adenocarcinoma (PDAC) is a lethal malignancy; its early detection is critical for improving prognosis. Electrochemiluminescent-based multiplex immunoassays were developed with high analytical performance. All proteins were analyzed in sera of patients diagnosed with PDAC (n = 138), benign pancreatic conditions (111), and healthy controls (70). The clinical performance of these markers was evaluated individually or in combination for their complementarity to CA19-9 in detecting early PDAC. Logistic regression modeling including sex and age as cofactors identified a two-marker panel of CA19-9 and CA-125 that significantly improved the performance of CA19-9 alone in discriminating PDAC (AUC: 0.857 vs. 0.766), as well as early stage PDAC (0.805 vs. 0.702) from intraductal papillary mucinous neoplasm (IPMN). At a fixed specificity of 80%, the panel significantly improved sensitivities (78% vs. 41% or 72% vs. 59%). A two-marker panel of HE4 and CEA significantly outperformed CA19-9 in separating IPMN from chronic pancreatitis (0.841 vs. 0.501). The biomarker panels evaluated by assays demonstrated potential complementarity to CA19-9 in detecting early PDAC, warranting additional clinical validation to determine their role in the early detection of pancreatic cancer.
Charging Optimization for Li-Ion Battery in Electric Vehicles: A Review

Battery electric vehicles (BEVs) are advocated due to their environmental benign characteristic. However, the long charging time and the degradation caused by fast charging impede their further popularization. Extensive research has been carried out to optimize the charging process, such as minimizing charging time and aging, of lithium-ion batteries (LIBs). Motivated by this, a comprehensive review of existing charging optimization (ChgOp) techniques is provided in this article. First, the operation and models for LIBs are explained. Then, unexpected side effects, especially for the aging mechanism (AM) of LIB associated with unregulated fast charging, are scrutinized. This provides a solid theoretical foundation and forms the optimization problem. Following this endeavor, the general framework with critical concerns for ChgOp system design is overviewed. Within this horizon, the state-of-the-art ChgOp techniques, clustered into open- and close-loop categories, are reviewed systematically with their respective merits and shortcomings discussed. Finally, the development of an emerging charging control protocol with both real-time affordability and degradation consciousness is further discussed as an open outlook.
Impact of a Personal Health Record Intervention Upon Surveillance Among Colorectal Cancer Survivors: Feasibility Study

Background There are currently an estimated 1.5 million individuals living in the United States with colorectal cancer (CRC), and although the 5-year survival rate has increased, survivors are at risk for recurrence, particularly within the first 2-3 years after treatment. National guidelines recommend continued surveillance after resection to identify recurrence early on. Adherence among survivors ranges from 23% to 94%. Novel interventions are needed to increase CRC survivors’ knowledge and confidence in managing their cancer and thus to increase adherence to follow-up surveillance. Objective The objective of this study is to develop and test the feasibility and efficacy of a stand-alone, web-based personal health record (PHR) to increase surveillance adherence among CRC survivors, with patient beliefs about surveillance as secondary outcomes. Methods A pre- and postintervention feasibility trial was conducted testing the efficacy of the colorectal cancer survivor (CRCS)–PHR, which had been previously developed using an iterative, user-centered design approach. Results The average age of the sample was 58 (SD 9.9) years, with 57% (16/28) male and the majority married (20/28, 71%) and employed full-time (15/28, 54%). We observed a significant increase in adherence to colonoscopy (before: 11/21, 52% vs after: 18/21, 86%; P=.005) and CEA (14/21, 67% vs 20/21, 95%; P=.01), as well as a slight increase in CT scans (14/21, 67% vs 18/21, 86%; P=.10). The only significant impact on secondary outcome (patient beliefs) was benefits of CEA test (P=.04), as most of the beliefs were high at baseline. Conclusions This feasibility study lays the groundwork for continued development of the CRCS-PHR to increase CRC surveillance. Patient-centered technologies, such as the CRCS-PHR, represent an important potential approach to improving the receipt of guideline-concordant care and follow-up surveillance, and not just for CRC survivors. Researchers should continue to develop patient-centered health technologies with clinician implementation in mind to increase patient self-efficacy and surveillance adherence.
A Novel Technology in Surveillance Video for Detecting and Forecasting a Robbing Incident

In this paper, a novel technology, which detects and forecasts human's abnormal behavior, is proposed. Taking an abnormal behavior, the robbery, as an example, the accuracy of the technology is demonstrated successfully. There are 3 innovations in this paper. A) A robbery incident is divided into 5 phases occurred orderly. By its order, a robbery is detected. B) By human body's motion character, the human body's speeds are measured in different areas and at different times. It improves the accuracy rate of a classifier. C) The technology can forecast an abnormal human behavior in a short time advance. Experiment shows that the technology detecting and forecasting accuracy are high enough to be used in practice.
A geometrical analysis of multiple viewpoint perspective in the work of Giovanni Battista Piranesi: an application of geometric restitution of perspective

This paper is a study of the work of the eighteenth-century Italian artist Giovanni Battista Piranesi. In it, selected etchings by Piranesi have been analysed by means of geometric restitution of perspective. Using this method it will be proved that the drawings of Ponte Fabrizio and Ponte Ferrato have been composed from multiple viewpoints. Piranesi has manipulated the conventional rules of perspective in order to produce a more believable and compelling representation of reality and subtly to influence our understanding of it. The paper presents a specific and detailed analysis of Piranesi's technique and reveals the sophisticated approach to perspective which he employed. It also gives an historical insight into the method of geometric restitution, explains how it operates and why it is useful, by employing it to analyse a series of etchings by Piranesi. It demonstrates that using precise geometrical methods may lead to new and exciting discoveries in the analysis of works of art. It is assumed that the reader has a basic understanding of the principles and constructions for vertical perspective. For more information refer to The basic constructions of perspective. 1 This will frame our way of thinking about perspective and provide an understanding of the projection methods. [The author was the winner of the 2007 RIBA President's Dissertation Medal; material additional to that in the article can be accessed in the multimedia section of the online version. ]
Antimicrobial Activities of Fungus Comb Extracts Isolated From Indo-Malayan Termite Macrotermes Gilvus Mound

The embodiment of antimicrobial components into the food packaging material has the ability to prevent microbial contamination. Fungus comb could be an alternative source of natural antimicrobial agents. In this study, n-hexane, ethyl acetate, methanol, and water extracts from fungus comb isolated from Indo-malayan termite Macrotermes gilvus Hagen mound were analysed for its antibacterial and antifungal activities against food spoilage microorganisms, including Escherichia coli ATCC 25922, Pseudomonas aeruginosa ATCC 27853, Staphylococcus aureus ATCC 25923, Aspergillus flavus, and Aspergillus niger. The antimicrobial activity of the fungus comb extracts was evaluated using Kirby-Bauer disc diffusion and microdilution method. The result showed that ethyl acetate extract exhibited the biggest diameter inhibition zone for all bacteria and fungi tested. Ethyl acetate extract showed antibacterial activity in all bacteria with minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) values of 0.39 mg/mL and 0.78 mg/mL, respectively. This extract also inhibited A. flavus and A. niger with MIC value of 0.78 mg/ml. Ethyl acetate extract contained guaiacol and syringol, which were predicted as the main antimicrobial components in fungus comb. Whereas n-hexane extract only inhibited Gram-positive bacteria. S. aureus ATCC 25923 was the most sensitive bacteria tested using all extracts. In addition, A. flavus was more sensitive compared to A. niger. Overall, fungus comb extract exhibited antimicrobial activity against E.coli ATCC 25922, P. aeruginosa ATCC 27853, S. aureus ATCC 25923, A. flavus, and A. niger. This study revealed that the fungus comb extract, especially ethyl acetate, could be considered as a new antimicrobial agent.
Evaluation of integrated optic modulator-based detection schemes for in-line fiber etalon sensors

This paper compares three classes of demodulation schemes for interpreting the static and dynamic response of in-line fiber etalon (ILFE) sensors. Each demodulation scheme employs path matched differential interferometry and an unbalanced integrated optic Mach-Zehnder interferometer as a readout interferometer. Active homodyne, synthetic-heterodyne and two types of pseudo-heterodyne based demodulators are evaluated. In the results presented here, signals generated by the ILFE ranging from quasistatic to about 100 Hz were recorded and compared with the signals generated by a resistance strain gauge, and were found to be in good agreement. >
Vibration Energy Harvesting on Vehicle Suspension Using Rotary and Linear Electromagnetic Generator

In this paper, we discuss comparation of vehicle vibration energy harvesting between rotary and linear electromagnetic generator. We construct the two model of energy harvester mechanism and then analyze both of energy absorbtion and vehicle comfortability. Furthermore, we analyze both of energy absorbtion and vehicle comfortability. Vehicle is modeled as quarter car. Rotarty generator harvests 2.5 x 10-4 Watt. The other hand, linear generator has viscous characteristic and capable to generates 90 Watts with 12 Volt power supply for 0.03 m amplitude of bumpy road input. Linear generator reduces oscillation with 1.2 sec settling time. It is more comfort than the angular which has 3 sec in settling time. With unnevenees road input, mean power of this generator is 64 Watt.
Effectiveness of Alberta Family-Integrated Care on Neonatal Outcomes: A Cluster Randomized Controlled Trial

Family-Integrated Care (FICare) empowers parents to play an active role as a caregiver for their infant in the neonatal intensive care unit (NICU). This model of care is associated with improved neonatal outcomes, such as improved weight gain and higher breastfeeding rates at discharge in infants admitted to level III NICUs; however, its effectiveness in level II NICUs remains unproven. The objective of this study was to evaluate the effectiveness of the model on neonatal outcomes in a cluster randomized controlled trial conducted in 10 level II NICUs randomized to Alberta FICare or standard care. Mothers and their preterm infants born between 32+0 and 34+6 weeks’ gestational age were included. The primary outcome was the proportion of infants who regained their birth weight (BW) after 14 days of life. The analysis included 353 infants/308 mothers at Alberta FICare sites and 365 infants/306 mothers at standard care sites. There was no difference in the proportion of infants who had regained their BW by 14 days between the groups. A lack of perceived improved weight gain trajectory for those in the FICare group is attributed to a shorter length of hospital stay and infants being discharged prior to regaining BW.
Aeroacoustic Simulations of Tandem Cylinders with Subcritical Spacing

Tandem cylinders are being studied because they model a variety of component level interactions of landing gear. The present effort is directed at the case of two identical cylinders with their centroids separated in the streamwise direction by 1.435 diameters. Experiments in the Basic Aerodynamic Research Tunnel and Quiet Flow Facility at NASA Langley Research Center have provided an extensive experimental database of the nearfield flow and radiated noise. The measurements were conducted at a Mach number of 0.1285 and Reynolds number of 1.66 ◊ 10 5 based on the cylinder diameter. A trip was used on the upstream cylinder to insure a fully turbulent flow separation and, hence, to simulate a major aspect of high Reynolds number flow. The parallel computational effort uses the three-dimensional Navier-Stokes solver CFL3D with a hybrid, zonal turbulence model that turns off the turbulence production term everywhere except in a narrow ring surrounding solid surfaces. The experiments exhibited an asymmetry in the surface pressure that was persistent despite attempts to eliminate it through small changes in the configuration. To model the asymmetry, the simulations were run with the cylinder configuration at a nonzero but small angle of attack. The computed results and experiments are in general agreement that vortex shedding for the spacing studied herein is weak relative to that observed at supercritical spacings. Although the shedding was subdued in the simulations, it was still more prominent than in the experiments. Overall, the simulation comparisons with measured near-field data and the radiated acoustics are reasonable, especially if one is concerned with capturing the trends relative to larger cylinder spacings. However, the flow details of the 1.435 diameter spacing have not been captured in full even though very fine grid computations have been performed. Some of the discrepancy may be associated with the simulation’s inexact representation of the experimental configuration, but numerical and flow modeling errors are also likely contributors to the observed differences.
Berechnung erdgedeckter Lagertanks nach Mang

Erdgedeckte Lagertanks, die einzeln im gewachsenen Boden gelagert sind (“Grabenlagerung”) und eine Erdüberdeckung von mindestens 1000 mm aufweisen, können nach dem Verfahren von Windels [1] sehr wirtschaftlich dimensioniert werden. Dieses Verfahren wurde in [2] ausführlich beschrieben und um alle vorkommenden betrieblichen und Montage‐Lastfälle erweitert. Die übrigen erdgedeckten Lagertanks werden nach dem Verfahren von Mang [3] entsprechend den Vorgaben in [4] ausgelegt. Dieses Verfahren wird in diesem Beitrag erläutert.
A Comparison of the Effectiveness of the RRT, PRM, and Novel Hybrid RRT-PRM Path Planners

Abstract: Sampling-based path planners develop paths for robots to journey to their destinations. The two main types of sampling-based techniques are the probabilistic roadmap (PRM) and the Rapidly Exploring Random Tree (RRT). PRMs are multi-query methods that construct roadmaps to find routes, while RRTs are single-query techniques that grow search trees to find paths. This investigation evaluated the effectiveness of the PRM, the RRT, and the novel Hybrid RRT-PRM methods. This novel path planner was developed to improve the performance of the RRT and PRM techniques. It is a fusion of the RRT and PRM methods, and its goal is to reduce the path length. Experiments were conducted to evaluate the effectiveness of these path planners. The performance metrics included the path length, runtime, number of nodes in the path, number of nodes in the search tree or roadmap, and the number of iterations required to obtain the path. Results showed that the Hybrid RRT-PRM method was more effective than the PRM and RRT techniques because of the shorter path length. This new technique searched for a path in the convex hull region, which is a subset of the search area near to the start and end locations. The roadmap for the Hybrid RRT-PRM could also be re-used to find pathways for other sets of initial and final positions. Keywords: Path Planning, Sampling-based algorithms, search tree, roadmap, single-query planners, multi-query planners, Rapidly Exploring Random Tree (RRT), Probabilistic Roadmap (PRM), Hybrid RRT-PRM
Innovative standstill position detection combined with sensorless control of synchronous motors

Sensorless control of PMSM's (Permanent Magnet Synchronous Motors) has occupied scientists for a long time. The result of this research is becoming widely accepted by the industry due to its low cost and reliability. However, the majority of today's motor drives are still equipped with some kind of position sensor. The reason is that sensorless control still have several limitations and is usually more complex than a traditional motor control. A new method to estimate the standstill position of PMSM's is presented. The method is based on the anisotropic properties of permanent magnets and is therefore referred to as MAM (Magnetic Anisotropy Method). The proposed method is independent of any ferromagnetic material and can therefore be used in many types of ironless PMSM's where standard methods fail. The MAM method is tested on a linear ironless motor, and measurement results from a "stripped" rotative motor without any supporting ferromagnetic material are also presented. Furthermore, it is shown in this thesis how Extended Kalman filters can be used to estimate the rotor position, and especially how the robustness and dynamic response of the overall control algorithm can be improved by using identification experiments and optimization algorithms. Some basic modelling of PMSM's are also presented. The modelling process is focused on techniques which are suitable for observers such as Extended Kalman filters. To show the versatility of the method, experimental results from two different motor types are presented. The first is a linear ironless motor while the second is a Hybrid Stepper Motor (HSM). Amongst other things it will be shown how the HSM can be transformed into a highly dynamic brushless DC motor without the drawbacks that is usually associated with HSM's. The linear ironless motor is used to demonstrate that it is possible to achieve good and robust position control without using a direct position sensor. Many different simulation and experimental results are presented for both the HSM and the linear ironless motor. The experiments are deliberately chosen to show both steady-state and dynamic operation of the proposed algorithm. The robustness of the overall algorithm is also analysed, considering unknown external load torque and motor parameters.
Nichtinvasive Bestimmung der Perfusion im Hirngewebe mittels Kernspintomographie

Einleitung; Die Perfusionsbildgebung des Hirngewebes ist ein wichtiges Hilfsmittel in der neurologischen Diagnostik. Sie liefert Informationen über die nutritive Versorgung und die Funktion des Organs und ist daher von wesentlicher Bedeutung in der Diagnose von neurovaskulären und degenerativen Erkrankungen. Ebenso gewinnt man Informationen über die Perfusionsverhältnisse bei Neoplasien. Traditionell war dieses Gebiet der Nuklearmedizin vorbehalten. Ausgehend davon waren es auch Indikatorverteilungsmethoden, die zuerst Anwendung in der Kernspintomographie fanden (1-3). Diese erfordern jedoch eine intravenöse Injektion von paramamagnetischem Kontrastmittel. Eine völlig nichtinvasive Methode zur Perfusionsbestimmung ergibt sich aus der Verwendung von arteriellen Wasserspins als natürlichen Indikator.
Improvement of left ventricular function with surgical revascularization in patients eligible for implantable cardioverter‐defibrillator

Left ventricular ejection fraction (EF) ≤ 35% is the cornerstone criterion for implantable cardioverter‐defibrillator (ICD) eligibility. Improvement in EF may occur in ICD‐eligible patients after coronary artery bypass graft surgery (CABG). However, the incidence, predictors, and outcomes of this process are unclear.
Selected Sports Bras: Comparisons of Comfort and Support

This study compared seven sports bras on quantitative and subjective measures of support and comfort for small, medium, and large breasted women during exercise. Fifty-nine subjects representing A, B, C, and D cup sizes were filmed while jogging on a treadmill at 6 mph in each bra style and in the nude condition. The average vertical displacement of the breast relative to the body was calculated for each condition. Subsequently, subjects completed questionnaires after engaging in vigorous exercise in each bra to assess subjectively comfort and support for each of the seven sports bras. Two-way repeated measures ANOVA's and subsequent pairwise comparisons indicated significant differences by bra style in subjective mean comfort scores and a significant interaction between subjects' cup sizes and subjective mean support scores. Pearson product moment correlation coefficients among vertical displacement values, subjective measures of support, and subjective measures of comfort indicated that bras that effectively controlled breast displacement tended to score lower on comfort. There were, however, exceptions to this trend, and no single bra rated well on all three measures of performance.
On the Capacity Performance of Hybrid FSO/RF System With Adaptive Combining Over Generalized Distributions

This paper investigates the ergodic capacity performance of hybrid free space optics (FSO)/ radio frequency (RF) system by employing an adaptive-combining-based switching scheme. In the adaptive combining scheme, the FSO and RF links are combined using the maximal-ratio combining (MRC) at the output, when the instantaneous signal-to-noise ratio (SNR) of the FSO link drops below a predefined threshold SNR value. The FSO link experiences the atmospheric turbulence, which is modeled using the generalized Malaga distribution, non-zero boresight misalignment or pointing errors, and atmospheric attenuation, under two types of detection techniques, i.e. heterodyne detection (HD) and intensity modulation/direct detection (IM/DD). Similarly, the fading of the RF link is characterized using the generalized $\kappa$–$\mu$ distribution. In particular, we derive the probability density function (PDF) of the instantaneous SNR of the adaptive combining scheme. Capitalizing on the SNR statistics, we obtain the unified closed-form ergodic capacity expressions for the adaptive-combining-based hybrid FSO/RF system. In addition, the asymptotic expressions for the ergodic capacity of the system at the high-SNR region are presented. All the derived analytical expressions are validated by using Monte-Carlo simulations. Numerical results and discussions are provided to compare the ergodic capacity performance of the adaptive-combining-based hybrid FSO/RF system with the existing system models such as single-link FSO, MRC-based hybrid FSO/RF, and hard-switching-based hybrid FSO/RF systems.