Miracle-dz/UniFAR-FTUs huggingface dataset:
The Personalized Approach to the Processing and Analysis of Patients' Medical Data

The application of machine learning technology and Big data to solve the problem of personalized approach in the tasks of making medical decisions and predicting states will allow to study random mechanisms of modeling and forecasting of treatment stages taking into account individual patient's characteristics, analysis of the medicaments and their key characteristics. We use this information to develop innovative approaches to risk forecasting, modeling therapies, and improving the quality of medical care by personalizing treatment schemes of patients. And it will allow you to effectively optimize data processing even when new information revenues come from different sources. The authors proposed the development of a System for the medical decisions support for the personalized data consolidation of the patient, which were receiving from the heterogeneous sources that are related healthcare. The conceptual scheme of the system was proposed and new approaches to consolidation and analysis of patient's data and forecasting of its states are offered. The use of various processing technologies for the Big data obtained will allow the study of random mechanisms for modeling and predicting treatment stages, taking into account individual patient's characteristics, analysis of the medicaments and their key characteristics. These will help develop innovative approaches to improve the risk stratification methodology, improve the quality of medical care by personalizing treatment schemes for patients.
Switching in coupled nonlinear photonic-crystal resonators

Using coupled-mode theory we examine the linear and Kerr nonlinear behavior of multiple consecutive photonic-crystal switches. Two types of resonators are considered, those with the cavity inside and those adjacent to the waveguide. We observe gap solitons in both structures and examine a nonlinear mode with energy localized near the boundaries of the finite system. Finally, we propose a device with two side-coupled resonators and a judiciously chosen intercavity distance that demonstrates switching at low powers. In addition to coupled-mode theory, rigorous simulations are performed for this structure.
High-speed rail and the city : urban dynamics and tourism Does high-speed rail affect destination choice for tourism purpose ?

S There is a growing but controversial literature concerning the link between high-speed rail (HSR) services and the tourism market. The aim of this paper is to identify this link in the case of two theme parks, namely Disneyland Paris and Futuroscope Parks, both served by an HSR station. Two revealed preference surveys were carried out interviewing tourists at both stations, with the objective of investigating the influence of HSRs on their decision to visit these theme parks. The results significantly diverge. In the case of Disneyland, tourists declared that the presence of HSR was fundamental in the choice of the destination; they would not have come without it. On the contrary, in the case of Futuroscope, tourists stated that HSR was not relevant. Indeed they would have come to Futuroscope in any case, also without this service. Moreover, the link between HSR and visiting other places close to these parks is also very different. These two case studies show again that the relationship between HSR and the local economic development in general and tourism in particular is very different according to places. HSR does not always contribute to the tourism market even in the case of a “stay tourism”. Si une littérature abondante se développe concernant le lien entre desserte ferroviaire à grande vitesse et tourisme, les résultats sont très controversés. L’objectif de cet article est d’identifier ce lien dans le cas de deux parcs à thème, Disneyland Paris et le Futuroscope, tous deux desservis par une gare TGV. Deux enquêtes fondées sur les préférences révélées ont été menées auprès de touristes pour tester l’influence de la desserte ferroviaire à grande vitesse sur leur décision de venir dans le parc à thème. Les résultats divergent fortement. Alors que dans le cas de Disneyland, la grande vitesse ferroviaire est importante puisque les touristes ne seraient pas venus sans elle, ce n’est pas le cas du Futuroscope : les touristes seraient venus même sans la desserte. Par ailleurs le lien entre la desserte et le fait de visiter d’autres lieux proches des parcs est aussi très différent. Ces deux cas montrent à nouveau que le lien entre la grande vitesse ferroviaire et le développement économique en général et le tourisme en particulier est très différent selon les lieux : la grande vitesse ne bénéficie pas toujours au tourisme même dans le cas d’un tourisme de destination. INDEX Mots-clés: desserte ferroviaire à grande vitesse, Parcs à thème, marché du tourisme, choix de destination
Phosphorous-based ionic liquids as condensing agent and medium for efficient esterification of carboxylic acids with alcohols and phenols

N-(diphenylphosphino)triethyl- and tributylammonium salts are introduced as easily prepared, cheap and stable ionic liquids that act as the condensing agent and media for the efficient esterification of acids with alcohols and phenols. This class of ionic liquids is immiscible with the ester products and thus allows simple and easy separation of the desired products from the reaction mixture.
On the stability of homogeneous solutions to some aggregation models

Vasculogenesis, i.e. self-assembly of endothelial cells leading to capillary network formation, has been the object of many experimental in- vestigations in recent years, due to its relevance both in physiological and in pathological conditions. We performed a detailed linear stability analysis of two models of in vitro vasculogenesis, with the aim of checking their potential for structure formation starting from initial data representing a continuum cell monolayer. The first model turns out to be unstable at low cell densities, while pressure stabilizes it at high densities. The second model is instead stable at low cell densities. Detailed information about the instability regions and the structure of the critical wave numbers are obtained in several interesting limit- ing cases. We expect that altogether, this information will be useful for further comparison of the two models with experiments. 1. Introduction. In living beings, complex structures arise from the aggregation of separate constituents. A typical example is given by the formation of the vascular network in vertebrates, where vascular endothelial cells migrate over long distances and finally coalesce to form complex vascular structures (11, 7). The process takes place during the early stages of embryo development and is therefore difficult to observe in its dynamical details. To circumvent this difficulty, severalin vitro as- says have been devised (4). In the experiments, cells are randomly seeded on the plain surface of a gel substratum and their migration and aggregation observed through videomicroscopy. In this way, the process of formation of a capillary-like network can be accurately tracked (1). Tracking of individual trajectories shows marked persistence in the direction of cell motion, with a small random component superimposed. Cells migrate over distances which are an order of magnitude larger than their radius and stick together when they get in contact with their neigh- bours. Motion is apparently directed towards zones of higher cell concentration, suggesting that chemotactic factors play a relevant role in the process. In a time of the order of some hours cells form a continuous multicellular network which can be described as a collection of nodes connected by chords (Fig. 1a). It is exper- imentally observed that i) the mean chord lengthis approximately independent on the initial cell density ( ¯ l ≃ 200 ±20¹ m); ii) connected networks are formed only above a critical density nc ∼ 100 cells/mm 2 (a phenomenon known as a percolative transition (12)); iii) at higher cell densities the chord thickness grows in order to ac- commodate a larger number of cells (Fig. 1b), until around 400 cells/mm 2 , a sort of
A Life-Cycle Overlapping-Generations Model of the Small Open Economy

We construct an overlapping generations model for the small open economy incorporating a realistic description of the mortality process. With age-dependent mortality, the typical life-cycle pattern of consumption and saving results from the maximizing behaviour of individual households. Our ‘Blanchard-Yaari-Modigliani’ model is used to analytically study a number of typical shocks affecting the small open economy, namely a balanced-budget public spending shock, a temporary Ricardian tax cut, and an interest rate shock. The demographic details matter a lot—both the impulse-response functions and the welfare profiles (associated with the different shocks) are critically affected by them. These demographic details furthermore do not wash out in the aggregate. The model is flexible and can be applied to a wide variety of theoretical and policy issues.
STR-839: ADDRESSING THE ISSUES OF MODAL IDENTIFICATION USING TENSOR DECOMPOSITION

Modal identification has been an indispensable tool for condition assessment of critical civil infrastructure. Recently several signal processing techniques including time-frequency analysis have shown significant success in addressing wide range of challenges in modal identification of flexible structures. In a parallel development, tensor decomposition is explored as an attractive and versatile system identification tool that can use even a limited number of vibration sensors to estimate the modal parameters under ambient excitations. In this paper, the performance of tensor decomposition is evaluated for modal identification of a building model under a multitude of earthquake excitations.
The effects of substratum on locomotor performance in lacertid lizards

Locomotion is important to animals because it has direct implications for fitness through its role in predator escape, prey capture, and territory defence. Despite significant advances in our understanding of animal locomotion, studies exploring how substrate properties affect locomotor performance remain scant. In the present study, we explore how variation in substrate (sand, slate, cork) affects locomotor performance in lacertid lizards that differ in morphology. Moreover, we explore whether substrate effects are the same for different types of locomotor performance (speed, acceleration, and stamina). Our results show that the substrate affected most types of locomotor performance studied but not always in the same way. Although substrate effects were species-dependent for the maximal speed over 50 cm and the distance run to exhaustion, this was not the case for acceleration capacity. These results suggest that substrate texture differentially affects burst performance versus longer duration measures of locomotor performance. Finally, straightforward relationships between habitat use and the substrate on which performance was maximized were not observed. This suggests that the evolution of locomotor capacity is complex and that animals may show compromise phenotypes allowing them to deal with a variety of substrates in their natural environment. © 2015 The Linnean Society of London, Biological Journal of the Linnean Society, 2015, ●●, ●●–●●.
The Politics of Trans-Saharan Transit Migration in the Maghreb: Ghanaian Migrants in Libya, c.1980 - 2012

This article analyses Libya’s changing status as both a migrant destination and a transit country. Libya and other Maghrebian states are said to be transit countries harbouring ‘illegal’ labour migrants from sub-Saharan Africa. Yet, when the Gaddafi regime fell in 2011, thousands of sub-Saharans including over 18,000 Ghanaian migrants headed south to their various countries of origin. Is transit migration a myth or a reality? How do African migrants view Libya? Are all migrants in Libya transiting to Europe? The main conceptual aim of this article is to interrogate the notion that Libya was the gateway for irregular migration to Europe. In this article, we argue that Libya has played different roles for different migrants: a destination to many and a transit for a minority. The shifting geopolitics of the region largely defines transit migration. The study’s analyses reveal that: (i) the application of the transit concept is ambiguous if not dubious and it mostly affected sub-Saharan migrants, (ii) the arrest, detention and deportation of migrant workers from Libya increased with the normalisation of relations with Italy, (iii) a majority of migrants view Libya as a destination country. Keywords : sub-Saharan Africa, transit, immigrant, migration, Maghreb
WORKING PAPER SERIES Centre for Competitive Advantage in the Global Economy

Using a newly collected dataset on inquisitorial activity for seven regions, fourteen provinces and 947 municipalities, I analyze the long-term economic consequences of the Spanish Inquisition (1478-1834). I show that inquisitorial activity is negatively associated to regional and provincial economic growth (an increase of a thousand inquisitorial trials is associated with 3% to 5% lower urbanization rates). At the municipal level, I find that municipalities affected by the Inquisition experienced an annual population growth rate 0.11% lower than their counterparts. This result is robust when controlling for alternative explanatory factors, such as pre-existent religiosity and proxies for trade activity. I explore three channels through which the Inquisition may have had an impact on economic outcomes. While inquisitorial activity is not linked to levels of trust or social polarization, I find it is negatively associated with the adoption of new technologies and the creation of municipal centres of cultural transmission. ∗I thank Robert A. Margo, Christophe Chamley and Carola Frydman for suggestions, encouragement and very constructive discussions. I also thank insightful comments from Regina Grafe, Sascha Becker, Greg Crawford, Eric Chaney, John Tang and participants at the Spanish Economic Association conference in 2012, Barcelona GSE Winter Meetings 2012, ASSA Meetings in 2013, Economic History Association Annual conference in 2013, WBZWorkshop on Political Economy, Economic History and Religion, and seminars at University of Sydney, University of Tasmania and European University Institute. Pau de Soto very generously shared his maps on Roman commercial routes and accessibility. All errors are mine. †Department of Economics and CAGE, University of Warwick. Email: J.Vidal-Robert@warwick.ac. uk
Dynamic Speckle Patterns (DSP) Analysis for Non-destructive Quality Assessment of Apple fruit during Storage

In this research, dynamic speckle patterns (DSP) at two wavelengths of 680nm and 780nm were acquired and analyzed for non-destructive quality assessment of apple fruit during storage. To this end, time history of speckle patterns (THSP) were created. Then, the statistical feature of inertia moment (IM) was extracted from the images to evaluate DSP activity of the samples during storage. Results indicated that DSP activity of apples is significantly affected by chlorophyll content. Moreover, DSP activity at 680nm was more than that at 780nm. On the other hand, DSP activity of the samples in the first and second months of the storage increased then decreased until the fourth month of the storage and after that increased again, relatively.
Fluorescent Reporters for investigating the Bacterial Stringent Response

The ``stringent response'' is a bacterial physiological adaptation to nutritional stress most well studied in the model organism \textit{Escherichia coli}. It is a research topic of interest both for increasing our understanding of bacterial physiology in general, and because of the potential for informing development of treatments for bacterial diseases. The small regulatory molecules penta- and tetra-guanosine phosphate, collectively referred to as (p)ppGpp, are known to be central in the regulation of the stringent response, but convenient methods for assessing intra-cellular concentrations of (p)ppGpp are currently lacking. One possible way to assess intracellular levels of a regulatory molecule is to place a ``reporter gene'' encoding a fluorescent protein, under transcriptional control of a promoter regulated by the molecule. Here, several plasmids encoding a variant of the green fluorescent protein (GFP) under different promoter sequences for this purpose have been constructed. The promoters differ with respect to whether and how they are effected by (p)ppGpp level, previous evidence showing either postive (up-regulation), negative (down-regulation) or indifferent (no \textit{direct} regulation) transcriptional response to increasing (p)ppGpp levels. Preliminary characterisation of GFP production directed by the different promoters, as measured by fluorescence, have been carried out with cells growing under both non-perturbed conditions and in the face of elevated (p)ppGpp levels. To elevate (p)ppGpp levels, production of a fragment of the ppGpp synthase RelSeq from \textit{Streptococcus equisimilis} was induced by use of a second plasmid.
A hybrid neural model for the production of sorbitol and gluconic acid using immobilized Zymomonas mobilis cells

Only ten years were enough for hybrid neural network-first principle models (HNM) reach a status of a standard industrial tool. This modeling strategy is employed here to represent the production of sorbitol and gluconic acid from glucose and fructose, using permeabilized and immobilized Zymomonas mobilis cells. Mass component balances are derived for the substrate concentrations. A multilayered neural network is used to represent the reaction rate. Experimental results were used to develop and validate the model. The HNM allows the elucidation of the phenomena involved in the process. It is observed from the results that the resistance for mass transfer from the liquid to the particles is increased at higher substrate concentrations and that the reaction rate depends on the concentrations of substrate and product in the particles. Additionally, it may be stated that the flexibility of the HNM allows the development of a model that would otherwise be difficult, if based solely on phenomenological principles.
Comparative Analysis of the Complete Chloroplast Genome of the Alloplasmic Sunflower (Helianthus L.) Lines with Various CMS Types

The complete chloroplast genomes of sunflower fertile line HA89 and isonuclear CMS lines with four different cytoplasmic backgrounds (PET1, PET2, ANN2 and MAX) were sequenced. A total of 451 polymorphic sites, with including 58 SSRs, 317 SNPs and 76 microindels were revealed between the fertile and CMS cytotypes. Among the alloplasmic male-sterile lines, cpDNA of CMS-MAX had the largest number of polymorphisms. The lowest number of polymorphic sites was revealed in CMS-PET1. Like as CMS-PET1, CMS-PET2 was obtained as a result of interspecific crossing between H. petiolaris and cultivated sunflower H. annuus. Nevertheless, the number of INDELs and SNPs in CMS-PET2 chloroplast genome was more than 4-fold and 6.5-fold higher than that in cpDNA of CMS-PET1. The average frequency of SNPs and INDELs in the non-genic regions and genic regions were 0.0062 and 0.0046, respectively. Increased mutation rates were found in the psbM-rpoB, rps16 intron, atpA-psbD, rps4-ndhJ and ndhc-atpE non-coding regions, as well as in the rpoC2, atpA, rbcL, ndhF and ycf1 genes. In addition to short insertions and deletions ranging from 1 to 5 bp, the relatively long INDELs (14-24 bp) unique for each CMS line were found. These insertions and deletions may be of use for PCR differentiation of the CMS lines due to differences in the amplicons length.
Electro-Stimulating Implants for Bone Regeneration : Parameter Analysis on Design and Implant Position

The aim of a clinical treatment which applies an alternating electromagnetic field using a screw implant to the weak bone in the femoral head is to speed up bone regeneration in case of avascular necrosis of the femoral head. A BISS (bipolar induction screw system), as the depicted ASNIS S-Series screw with integrated coil and electrodes, is the subject matter of this project. Numerical simulation of the electric field caused by the ASNIS-s screw in the femoral head was carried out using the finite element method. Effects of different designs of the ASNIS-s screw on electric field distribution were studied. Three kinds of design variations were completed, such as shape of the screw tip, position of the screw in the femoral head and size of the isolation area in the screw.
Fraud and Tamper Detection in Authenticity Verification through Gradient Based Image Reconstruction Technique for Security Systems

Authenticity verification for security systems is a very important research problem with respect to information security. One of the principal problems in image forensics is determining if a particular image is authentic or not. This can be a crucial task when images are used as basic evidence to influence judgment like, for example, in a court of law. Image editing software like Adobe Photoshop, Maya etc. and technically advanced digital photography are used to edit, manipulate or tamper the images easily without living obvious visual clues. The abusive use of digital forgeries has become a serious problem in various fields like authenticity verification, medical imaging, digital forensic, journalism, scientific publications etc. To carry out such forensic analysis, various technological instruments have been developed in the literature. In this paper the problem of detecting if an image has been forged is investigated. To detect tampering and forging, a novel methodology based on gradient based image reconstruction is proposed. Our method verifies the authenticity of image in two phases- modeling phase; where the image is reconstructed from its gradients by solving a poisson equation and forming a knowledge based model and simulation phase; where the absolute difference method and histogram matching criterion between the original and test image is used. Such a method allows concluding that if a tampering has occurred. Experimental results are presented to demonstrate the performance of our gradient- based image reconstruction approach and confirm that the technique is able to verify whether a forged image is presented to a security system for authenticity verification. Through this unique mechanism, one can secure the most reliable information and forging or tampering of images for gaining false authentication and hence fraud can be detected.
An Approach to Automatically Check the Compliance of Declarative Deployment Models

The automation of application deployment has evolved into one of the most important issues in modern enterprise IT. Therefore, many deployment systems have been developed that process deployment models for automating the installation of systems. Creating such deployment models becomes more and more complex as compliance plays an increasingly important role. Not only external laws and regulations must be considered, but also a company’s internal requirements must be fulfilled. However, this is a very complex challenge for the modelers as they require a firm knowledge of all the compliance rules that must be observed. As a result, this often leads to deployment models that violate compliance rules due to manual modeling mistakes or because of unawareness. In this paper, we introduce an approach that enables modeling of reusable Deployment Compliance Rules that can be executed automatically to check such regulations in declarative deployment models at design time. We validate our approach with a prototype based on the TOSCA standard and the OpenTOSCA ecosystem.