rsV HOsPItALIZAtION IN AbOrIGINAL INFANts IN tHE cANADIAN rEGIstrY OF sYNAGIs® (cArEss) FOLLOWING PrOPHYLAXIs (2005 – 2012)

conversion symptoms. The most common presentations were disturbance of voluntary motor function (48%), pseudoseizures (25%), sensory symp-toms (19%), visual deficits (10%), hearing deficits (2%), gastrointestinal problems (2%), and inability to speak (2%). Hospital admission in order to determine diagnosis was required for the majority (87.5%) of cases, with an average stay of 15.6 days (range 3 to 104); standard deviation of ± 20.5 days. The average number of subspecialists involved in the diagnostic work-up of these youth was 4.5. Antecedent stressors (family conflict, academic pressure, peer pressure, abuse) were reported in 92% and a prior history of mental health concerns in 35%. Thirty-eight percent of cases were associated with a positive family history of anxiety or depression. Psychotropic medications for anxiety or depression had been previously prescribed in 15% of patients. The average duration of symptoms, from time of onset to diagnosis, was approximately 12 months. conclusions: Conversion disorder is associated with a significant burden for the adolescent, family, and the Canadian health system. Preliminary data from the CPSP study suggests an association of CD with anxiety and depression and highlights the potential impact of life stressors in addition to, more extreme stressors such as loss of an attachment figure and previous history of physical and/or sexual abuse. Background: Hyponatremia associated with hypotonic maintenance intravenous (IV) fluid administration is increasingly recognized as a cause of morbidity and mortality. Previous research has focused on post surgical and intensive care populations. There have been no trials examin-ing optimal IV maintenance fluid for non-ICU, non-surgical hospitalized the outcome measures between the groups. In the general pediatric non-ICU, non-surgical population studied both IV solutions are likely acceptable options for maintenance fluids, provided that serum Na and fluid balance are carefully monitored. Background: Aboriginal infants have substantially higher risks for respiratory illness (RI) and respiratory syncytial virus (RSV) hospitalizations compared to non-Aboriginal infants. oBjectives: The purpose of the present study was to compare hospital- ization rates for RI events and RSV infection in Aboriginal versus non-Aboriginal infants in the CARESS database. p=0.207). In terms of RSV-positive hospitalizations, there was no significant difference between CF and MD (0.54% vs. 2.22%; p=1.000) or SD (1.48%; p=0.232). In the Cox proportional analysis, hazard ratios of time to first RSVH in CF were similar to SD (Exp[B]=0.354, 95% CI 0.049–2.531; p=0.301) and MD (Exp[B]=0.268, 95% CI =0.037–1.968; p=0.196). Background: Early development in autism spectrum disorders (ASD) is increasingly studied using prospective ‘high-risk’ designs, focused on infants at risk by virtue of having an affected older sibling. However, the comparability of children with ASD ascertained from high-risk cohorts versus those ascertained by clinical referral has never been examined. oBjectives: To compare the sex ratio, symptom severity and adaptive functioning of preschool children with ASD ascertained from a high-risk longitudinal sibling cohort (HR-ASD) to those diagnosed following refer- ral to a developmental clinic (clin-ASD). design/Methods: The HR-ASD group (n=94) were identified as part of an ongoing multi-site prospective study of HR siblings. ASD diagnoses were established shortly after the child’s 3rd birthday, using the Autism Diagnostic Interview – Revised (ADI-R), Autism Diagnostic Observational Schedule (ADOS) and expert clinical judgement. The clin-ASD group (n=176) were identified from an inception cohort of clinically diagnosed children with ASD participating in a longitudinal study. To ensure comparability by age, only children diagnosed at age 3 were included. Categorical variables (sex, language level) were compared using χ 2 , and continuous variables (eg, adaptive functioning, indexed by the Vineland Adaptive Behavior Schedule - II; VABS-II) were compared using ANOVA. results: The clin-ASD group was older than the between HR-ASD (2.2:1) by the severity metric and ADI-R social, communication and behavioral subscales were less in the group (all marked differences in parent-reported language level (on in in pared tive Composite Standard incorporating and (within did any or interactive for these versus clin-ASD differences essentially conclusions: Compared to clinically referred children with ASD, those ascertained from a HR cohort had less severe ASD symptoms, higher levels of language and adaptive functioning, and proportionately included more girls. These differences may reflect referral and ascertainment biases across the two cohorts, with important practice implications.