Miracle-dz/UniFAR-FTUs huggingface dataset:
Effect of Alginite on Some Antioxidant Indexes in Extracts of Two Variants of Mentha and Their Toxicity

© Slovak University of Agriculture in Nitra www.uniag. sk Introduction The current research is focused on the field of organic farming “bioagriculture“ production of feedstuffs, which can contribute essentially to animal and human health and are environmentally friendly. One of the main requirements in the bioagricultural production is the usage of organic fertilizers instead of synthetic substances. Alginite is a complex soil aggregate of algae-based biomass from an organo-mineral origin (Kúšik et al., 2017; Brindza et al., 2021a, b) with high water absorption capacity (Valla et al., 1980), thus can be used as a natural organic fertilizer. The most effective usage of alginite is attributed to agricultural production as a natural fertilizer (Elečko et al., 1998). Slovakia has in Princiná, Lučenec district, one of the largest alginite deposits in Europe suitable for mining (Kulich et al., 2002). Effect of alginite on some antioxidant indexes in extracts of two variants of Mentha and their toxicity
Conception of bi-band rectangular microstrip array antenna

Narrow band is the major inconvenient of the microstrip antenna. However, various multiband techniques are proposed towards several applications. A simple configuration of the rectangular microstrip antenna allows operating a system of satellite communication in two bands. The configuration consists of a single radiant element and substrate with low dielectric constant. The antenna is fed by a micro-strip line attached in the corner of the patch. This antenna covers two bands, the K and Ku bands, simultaneously. With the same parameters as simple antenna, other shapes are compared with rectangular array antenna, to improve the performances of the antenna and vary their operating frequencies. The designated configurations of the antenna arrays contain 2, 4 and 8 radiating elements.
Social overcrowding impacts gut microbiota, promoting stress, inflammation, and dysglycemia

ABSTRACT An array of chronic inflammatory diseases, including metabolic diseases such as obesity and diabetes, are thought to be promoted by disturbance of the intestinal microbiota. Such diseases disproportionately impact low-income communities, which are frequently afflicted by chronic stress and increased density housing. Hence, we hypothesized that overcrowded housing might promote stress, microbiota dysbiosis, inflammation, and, consequently, metabolic diseases. We tested this hypothesis in a tractable murine model of social overcrowding (SOC), in which mice were housed at twice normal density. SOC moderately impacted behavior in some widely used assays (Open Field, Elevated Plus Maze and Light/Dark tests) and resulted in a stark increase in corticosterone levels. Such indices of stress were associated with mild chronic gut inflammation, hyperglycemia, elevations in colonic cytokines, and alterations in gut microbiota composition. All of these consequences of SOC were eliminated by broad spectrum antibiotics, while some (inflammation and hyperglycemia) were transmitted by microbiota transplantation from SOC mice to germfree mice housed at normal density. Altogether, these results suggest a central role for intestinal microbiota in driving stress, inflammation, and chronic diseases that are promoted by overcrowded housing.
Impact of Track and Trace Integration on Pharmaceutical Production Systems

In today's competitive economic environment, track and trace (the capability to determine present and past locations of products through the whole supply chain) is becoming an increasingly urgent necessity and a key differentiator in many industries, enhancing pilferage reduction, counterfeit prevention and targeted recalls, and improving supply chain efficiency, synchronization, visibility, and security. The pharmaceutical industry, together with the food industry, is one of the most advanced in traceability system implementation, as it has found to be strongly affected by the counterfeiting phenomenon. In this paper, a brief overview of traceability international regulations in the pharmaceutical sector and of the impact of its implementation on production processes and logistics will be continued, in order to highlight the main drivers of its large and fast diffusion. Technologies developed will also be presented and criticalities, and the benefits of traceability system implementation will be analysed.
Anti-Proteinase 3 Antibodies as a Biomarker for Ulcerative Colitis and Primary Sclerosing Cholangitis in Children

ABSTRACT Objectives: Anti-neutrophil cytoplasmic antibody (ANCA) directed against proteinase 3 (PR3) is a marker for granulomatosis with polyangiitis, but is also found in patients with inflammatory bowel disease (IBD), mainly ulcerative colitis (UC). The aim of our study was to investigate ANCA and PR3-ANCA in paediatric IBD. Methods: We tested 326 paediatric IBD patients and 164 controls for anti-Saccharomyces cerevisiae antibodies (ASCA), ANCA (indirect immunofluorescence, IIF) and PR3-ANCA (chemiluminescence immunoassay). We applied the Paris classification for paediatric IBD and documented liver manifestations such as primary sclerosing cholangitis (PSC) and autoimmune hepatitis (AIH). Results: We found PR3-ANCA in 49/121 (40%) of UC, 20/187 (11%) of Crohn disease (CD) and 2/18 (11%) of IBD-unclassified (IBD-U) patients but in none of the controls. 54% UC and 12% CD patients were positive for ANCA (IIF). PR3-ANCA positive UC patients were characterised by more extensive disease (P = .070). Fourteen of 21 (67%) of UC patients with backwash ileitis were anti-PR3 ANCA-positive (P = .011). We diagnosed PSC or PSC/AIH in 19 UC and 3 IBD-U patients. Fifteen of 22 (68%) patients with PSC or PSC/AIH were anti-PR3-ANCA positive in contrast to 36 of 117 (32%) patients without PSC (P = .001). PR3-ANCA positive patients showed higher levels of gamma-glutamyl transferase, alanine transaminase and aspartate transferase (P < 0.001, 0.001, 0.006, respectively). Forty-seven percent of CD and 6% of UC patients were ASCA-IgA positive. PR3-ANCA-positive and -negative patients showed no significant differences concerning age at diagnosis, disease activity, need for drugs, and number of hospitalisations. Conclusions: Our study provides data for PR3-ANCA as a potential serological marker for paediatric UC and PSC.
Running title: KPC in carbapenem-resistant K. pneumoniae in Israel

* Correspondence: Yehuda Carmeli, MD, MPH, Division of Epidemiology, Tel Aviv Sourasky Medical Center, 6 Weizmann St., Tel Aviv 64239, Israel Phone: 972 3 692 5644, Fax: 972 3 697 4966 E mail: yehudac@tasmc.health. gov.il CC EP TE D Copyright © 2007, American Society for Microbiology and/or the Listed Authors/Institutions. All Rights Reserved. Antimicrob. Agents Chemother. doi:10.1128/AAC.00299-07 AAC Accepts, published online ahead of print on 11 June 2007
Structural Robustness Analysis and the Fast Fracture Analogy

Progressive collapse of building structures is analogous in terms of energy to the theory of unstable fast fracture. When a structure deflects due to damage of a member, progressive collapse will occur if the work done by gravity is greater than the energy absorbed by the destroyed member and other damaged members. The main difference between fast fracture in a cracked plate and progressive collapse of a building is that the latter is dynamic and it is possible to evaluate the kinetic energy of the structure as it collapses. By consideration of all of the energy components, the mechanism of progressive collapse may be studied in terms of energy. The fast fracture analogy has been incorporated in a procedure that searches systematically for damage scenarios leading to collapse of a structure. The most critical scenario is the one that requires the least amount of damage energy. This minimum damage energy is proposed as a measure for the robustness of the structure.
Influence of emotions displayed by employees during service recovery

Purpose While research evidences how customers’ emotions can influence their consumer experience, understanding of how employees’ displayed emotions affect the customer service experience is more limited. Drawing on affect transfer theory, the authors test for the mediating role of attitude towards the employee, which is proposed to mediate the effect of employees’ displayed emotion on customers’ satisfaction with recovery. As service recovery entails a critical service experience in which emotions can easily rise, this paper aims to highlight the pivotal role of employee-displayed emotions during service recovery. Methodology A scenario-based experiment in the context of an airline service failure recovery (3 × 2 between-subjects design) manipulates frontline employees’ emotions (anger vs happiness vs no specific emotion) and the quality of the solution (bad vs good). Findings Employees’ displayed emotions directly affect attitude towards the employee and indirectly affect service recovery satisfaction. Moreover, attitude towards the employee is affected more by the employee’s displayed emotion when the solution offered is bad compared to good. Practical implications Employees’ emotions displayed during service recovery can enhance or damage service recovery strategies. Employees should control for negative emotions in the case of service failure, especially when unable to provide a good solution. Originality Emotions displayed by employees can influence the customer’s service recovery evaluations. There is an interesting interaction between the quality of the solution and employees’ displayed emotions. Additionally, the mantra of “service with a smile” may not be valid in the case of service recovery: rather, employees should avoid displaying negative emotions.
Modeling and analysis of a three-phase unity power factor current injection rectifier using one loop control strategy

In this paper, a new control strategy based on the pulse-width-modulation (PWM) control technique and using a single feedback current loop is proposed. The control scheme is applied to a particular three-phase unity power factor (UPF) current injection AC-DC converter. For this purpose, a dynamical model of the converter is developed using the state-space averaging method. Simulation results are used to validate the theoretical approach carried out through the paper.
Optimal multiuser detection of bandlimited DS-CDMA signals, distorted by time-varying, frequency-selective multipath channels

We have addressed the problem of optimum multiuser detection for bandlimited signals distorted by a time-varying, frequency selective channel, and corrupted by additive Gaussian noise. We have derived the MLSE receiver for this channel using the familiar concept of matched filtering. A performance analysis for Rayleigh fading and white noise is in good agreement with simulations. We propose this optimal multiuser receiver as a benchmark for comparing the performance of other detectors. Many other receivers exhibit a BER floor in fast time varying channels and therefore are unsuitable as a reference. As a final note, realisations of the optimal receiver using different metrics, for example, the squared Euclidean distance metric, can be derived easily.
The effect of plyometric exercises on the selected biomechanical parameters of breaststroke among male swimmers aged 10-14

In swimming tournaments, a good swim start can help the swimmer achieve a good record. The present paper aims to compare the effect of two plyometric exercises in water and on land on breaststroke grab and track starts among male swimmers. 20elite swimmers were divided into in-water and on-land groups. Swimmers’ performance variables include anaerobic power of hands and legs, 25-meter record, the time of contact of head with water and the time of keeping movement in water, flying distance from the starting point to the end point of contact with water and the distance of continuing movement after entering water using both start techniques, the number of movements of hands and legs in 13 meter breaststroke swimming without start and glide. Mean and standard deviation were used to describe the sample, and MANOVA at P≤0.05 was used to determine intergroup difference. A significant difference was seen in the time mean of head contact with water in both start techniques of breaststroke swimming; in addition, there is a significant difference in number mean of hand movements and leg movements in breaststroke swimming as well as the number of hand and leg movements in full 13 meter breaststroke swimming after polymeric exercise in both groups. It seems that plyometric exercises improve and enhance the measured parameters in both on-land and in-water groups, so the use of these exercises to improving swimmers’ start performance is recommended. The effect of plyometric exercises on the selected biomechanical parameters of breaststroke among male swimmers aged 10-14.
The use of ICTs as tools that assist Digital Natives enhance their own learning

There is no argument that the present chronological period is one of the most rapid periods of technological transformation ever as no major aspect of modern life has been untouched by the way the information technologies are used. This transformation has a serious impact on the way the educational system is structured as it has to deal with the first generation of students that were born in a network society and raised assimilating technologies. Research findings indicate that this generation, often called ‘Net Generation’, ‘Digital Natives’, ‘Y Generation’ or ‘Millennials’, share unique characteristics because of their interaction with all those toys and tools of the digital age which consequently have changed their thinking patterns. This paper aims to provide a review of the literature regarding digital natives, address the main characteristics of theirs, that set them apart from previous generations, and present how different tools and applications from the digital age have the potential to assist students enhance their own leaning.
Durable Response to Brentuximab Vedotin Plus Cyclophosphamide, Doxorubicin, and Prednisone (BV-CHP) in a Patient with CD30-Positive PTCL Arising as a Post-Transplant Lymphoproliferative Disorder (PTLD)

T-cell PTLDs are lymphoid proliferations that develop in recipients of SOT or allogeneic HSCT. They carry an extremely poor prognosis with a reported median survival of only 6 months. The infrequency with which they are encountered makes treatment a challenge due to the lack of prospective trials to guide management. The significantly higher risk of morbidity and mortality in T-cell PTLD, compared to B-cell PTLD, underscores the challenge of treating these patients and the need for new therapeutic options. Brentuximab vedotin, an ADC targeting CD30, is FDA-approved in combination with CHP as front-line treatment for patients with CD30 expressing PTCL. Herein we report a case of CD30-positive T-cell PTLD that was successfully treated with BV-CHP, suggesting the added value of the addition of BV to chemotherapy, contributing to our patient’s long and ongoing progression-free survival. To our knowledge, this is the first documented case of successful treatment using BV-CHP for a CD30-positive, EBV-negative, late T-cell PTLD.
Optimising network transfers to and from Queen Mary University of London, a large WLCG tier-2 grid site

Optimising network performance is key to high bandwidth data transfers required for a Tier-2 site. We describe the techniques we have used to obtain good performance. Monitoring plays a key part, as does the elimination of bottlenecks and tuning TCP window sizes. Multiple parallel transfers allowed us to saturate a l Gbit/s link for 24 hours - whilst still achieving acceptable download speeds. Source based routing and multiple data transfer servers allowed us to use an otherwise unused "resilient" link.
High Free‐Tropospheric Aitken‐Mode Aerosol Concentrations Buffer Cloud Droplet Concentrations in Large‐Eddy Simulations of Precipitating Stratocumulus

A new Aitken mode aerosol microphysics scheme is developed for a large eddy simulation model in order to better investigate cloud‐aerosol interactions in the marine boundary layer and to study the Aitken buffering hypothesis of McCoy et al. (2021), https://doi.org/10.1029/2020jd033529. This scheme extends the single‐mode two‐moment prognostic aerosol scheme of Berner et al. (2013), https://doi.org/10.5194/acp-13-12549-2013. Seven prognostic variables represent accumulation and Aitken log‐normal aerosol modes in air and droplets as well as 3 gas species. Scavenging of interstitial and other unactivated aerosol by cloud and rain drops are treated using the scheme described in Berner et al. (2013), https://doi.org/10.5194/acp-13-12549-2013. The scheme includes coagulation of unactivated aerosol and a simple chemistry model with gas phase H2SO4, SO2, and DMS as prognostic variables to capture basic influences of sulfur chemistry on the model aerosols. Nucleation of H2SO4 aerosol particles from gas‐phase H2SO4 is neglected. A deep, precipitating stratocumulus case (VAMOS Ocean Cloud Atmosphere Land Study RF06) is used to test the new scheme. The presence of the Aitken mode aerosol increases the cloud droplet concentration through activation of the larger Aitken particles and delays the creation of an ultraclean, strongly precipitating cumulus state. Scavenging of unactivated accumulation and Aitken particles by cloud and precipitation droplets accelerates the collapse. Increasing either the above‐inversion Aitken concentration or the surface Aitken flux increases the Aitken population in the boundary layer and prevents the transition to an ultraclean state.
Freight Routing and Scheduling at CSX Transportation

Two of a railroad’s fundamental tactical operations are routing shipments along its rails and scheduling trains necessary to service the routes. The computer-aided routing and scheduling system (CARS) bridges the gap between these day-to-day operations and strategic planning. By investigating low-cost routes and schedules in a controlled environment under various cost scenarios, CSX Transportation’s strategic planners can better account for these tactical operations in their long-range policies.
Modified Synthesis and Physicochemical Characterization of a Bioglass-Based Composite for Guided Bone Regeneration

Objectives Bioglass composites and polymers are materials of great interest for the medical and dental areas due to their properties, combining the bioactivity of ceramic materials and the mechanical properties of polymers. The purpose of the present study was to develop and to characterize the physicochemical and morphological properties an experimental bioglass-based ternary composite composed associated with sodium carboxymethylcellulose (Na-CMC) and polyvinyl alcohol (PVA). The compatibility of functional groups with bioglass was previously evaluated. The composite was then synthesized and evaluated in terms of morphology, elemental composition, compressive strength, porosity, and bioactivity. Materials and Methods The bioglass was previously synthesized using a sol-gel route and characterized using FTIR analysis to identify the functional groups. The bone graft composite was then synthesized associating the bioglass with PVA, surfactant Triton X, and Na-CMC. The composite was then morphologically characterized using SEM/EDS. The porosity of the composite was analyzed using µCT, which also provided the composite compression strength. The composite was then evaluated in terms of its bioactivity using SEM/EDS analyses after immersion in SBF for 12, 24, 48, and 72 h. Results FTIR analysis confirmed, among other components, the presence of Si–O–Ca and Si–O–Si bonds, compatible with bioglass. SEM analysis exhibited a composite with a porous structure without spikes. The elemental mapping confirmed the presence of Si, Ca, and P in the composite. µCT analysis demonstrated a porous structure with 42.67% of open pores and an average compression strength of 124.7 MPa. It has also demonstrated ionic changes in the composite surface after immersion in SBF, with increasing detection of Ca and P as a function of time, highlighting its chemical bioactivity. Conclusions It can be concluded that the proposed bioglass-based composite presents a three-dimensional, well-structured, chemically bioactive porous structure, mechanically resistant for being reinforced with polymeric phases, with promising results as a synthetic bone graft, which makes it suitable for guided bone regeneration.
Process parameters effect on cutting forces and geometrical quality in thin wall micromilling

Micromilling is one of the most geometrically versatile tooling processes, in fact three-dimensional features can be effectively manufactured on molds and dies achieving a good accuracy performance. Typical and challenging features for these microcomponents are high aspect ratio thin walls. The present study evaluates the effect of wall thickness, milling strategy and tool path on cutting forces in 0.4 % carbon steel (C40) thin wall micromilling. An experimental campaign has been designed in order to statistically analyse the cutting force responses and a proper technique (ANalysis of COVAriance) has been applied to remove the tool wear effect. Considerations drawn in the present paper on micromilling cutting forces have been coupled with previous knowledge of the same authors, regarding the process parameters direct link with the thin wall geometrical quality, in order to study the feasibility of a general approach able to meet tolerances by controlling forces.
Testing Calibration Issues in Resistance Drilling Applied to Timber Elements

Diagnosis of current state of timber components in existing buildings is supported by investigation tools applied onsite as non-destructive (ND) and minor-destructive (MD) test procedures [1] [2]. Among them, resistance drilling devices (e.g., Resistograph®) [3] are commonly used to check the conservation condition of wood and detecting possible inner flaws, joints, etc. This device provides a densimetric profile along the investigated section, based on the drilling power consumption (RM) of a thin long needle driven into the wood at speed rates kept constant by electronic control [4]. Being a local test method, timber components in existing buildings often require multiple measures, depending on specific problems to investigate (e.g., beam ends threatened by moisture due to masonry contact, presence of decay, cracks), which progressively change the needle conditions. The paper investigates the influence of consumption of the needle tip due to wear by comparing the profile results obtained on a series of 21 old and 12 new timber beams, representative of various species (spruce, larch, oak, elm, pine) in different conditions (e.g., presence of joints, moisture content). Each beam was investigated on two adjacent sides with about 4 to 10 measurement stations per side. The consumption of the needle tip was first quantified by testing a spruce board element (27 mm thick at 12% MC, classified as C24 according to UNI EN 338 (2016) [5] at various speed rates (drill one kept constant when feed one varying and vice versa), which provided data for test calibration according to this specific issue. The C24 element was then applied before the timber surface of the investigated beams to compute normalized values of RM, which can be considered more representative of the evaluation of the actual state of wood and more reliable for the test repeatability and the comparison among different cases and conditions.