Miracle-dz/UniFAR-FTUs huggingface dataset:
Trigger Points and Central Modulation—A New Hypothesis

ABSTRACT Objective: A new hypothesis is proposed to explain the pathogenesis, symptomatology, and treatment of the trigger points [TrPs], which define the myofascial pain syndrome [MPS]. Hypothesis: TrPs are formed due to sustained α-motoneuron plateau depolarization, which is maintained by one of two different central nervous system [CNS] mechanisms. “Antecedent” TrPs are formed in withdrawal reflex agonist muscles due to central sensitization of the C fiber nociceptive withdrawal reflex [NWR], visceromotor reflex [VMR], or nociceptive jaw-opening reflex [NJOR]. “Consequent” TrPs result in withdrawal reflex antagonist muscles due to compensatory reticulospinal or reticulo-trigeminal motor facilitation. Afferent nociceptive signals arise from both latent and active TrPs. However, latent TrPs are not spontaneously painful, because of complete inhibition of nociceptive transmission at the spinal cord or trigeminal nucleus [SC/TN] levels. Marked SC/TN sensitization [especially with a reduced antinociceptive functional reserve] may overwhelm the brainstem antinociceptive mechanism, going beyond the MPS into the generalized allodynia of the fibromyalgia syndrome [FMS]. The principal brainstem nuclei involved in TrP sensory and motor modulation have other diverse homeostatic roles; therefore TrP-induced brainstem dysfunction may contribute to the pathogenesis of a variety of sensory, motor, and autonomic disorders. Treatment involves noxious stimulus-induced transient inhibition of the CNS mechanisms that sustain TrPs. This allows stretching of the contractured muscle fibers to resolve the TrP local energy crisis, and to reverse muscle nociceptor and CNS sensitization. Conclusion: This hypothesis proposes that TrPs result in the muscles due to sustained α-motoneuron plateau depolarization. Descending inhibition normally ensures that most TrPs remain latent, but FMS may result if this inhibitory mechanism is overwhelmed.
Echelle spectroscopy of CD -41 deg 13967 - The young central star of a new planetary nebula

High-resolution CCD spectra obtained with the Palomar 1.5-m echelle spectrograph and subsequently confirmed and extended using the CTIO 4-m echelle spectrograph have revealed that the hot star CD -41°13967 is the young central star of a previously unknown low-excitation planetary nebula. A detailed analysis of the CCD spectra is presented.
Alocação dinâmica de largura de banda para redes sem fio infraestruturadas

A demanda por redes sem fio tem crescido nos últimos anos, isto implica em uma maior necessidade de melhoria em seu desempenho. O padrão IEEE 802.11ac permite utilizar canais com largura de banda maiores que 20 MHz. Porém, os pontos de acesso alocam a largura de banda do canal estaticamente, independente das configurações dos clientes. Isso leva a um baixo desempenho da rede. Neste trabalho, propomos um sistema que permite aos clientes escolherem a largura de banda para se conectar aos pontos de acesso. O sistema foi validado através de experimentos reais. Destacamos o compromisso entre latência e vazão. Os resultados mostram que nosso sistema melhora o uso do espectro de frequência.
Motion modelling for respiratory motion estimation in minimally invasive cardiac interventions using intraprocedure ultrasound data

Respiratory motion of the heart limits the utility of image-guided cardiac interventions, causing misalignments between the pre-procedure information used for guidance and the intra-procedure moving anatomy and instruments. As a result, the guidance can be misleading, compromising the accuracy and success of the intervention. Respiratory motion models have been proposed to estimate and correct for respiratory motion, but to date their clinical uptake has been very limited due to a lack of accuracy and robustness, and the interruptions that they typically introduce into the clinical workflow. The scope of this project was to devise methods to address these limitations and foster the clinical translation of respiratory motion models. A novel Bayesian respiratory motion model was developed in the first part of the project. The Bayesian framework enables the combination of the robustness of a pre-procedure motion model derived from Magnetic Resonance Imaging with the intraprocedure information provided by 3D echography (echo) images. The main novelties of the approach lie in its probabilistic formulation and its ability to adapt to variable breathing patterns. The Bayesian motion model was further evaluated using live 2D echo images, proving to be accurate using both 2D and 3D echo images. Furthermore, a new motion model-driven echo acquisition framework was developed to acquire 2D echo images that automatically compensates for respiratory motion. The second part of the project addressed the limitations associated with the dynamic calibration scan used to derive the motion model, the acquisition of which causes interruptions to the clinical workflow. A personalisation framework for populationbased motion models that uses anatomical features to predict cardiac respiratory motion was developed. Results show an average value for the 50th and 95th quantiles of the estimation error of 1.6mm and 4.7mm respectively, without the need for a subject-specific dynamic calibration scan. Finally, the above mentioned parts were combined to produce a personalised Bayesian motion model. The technique is accurate and does not significantly complicate the clinical workflow, thus making it suitable for clinical uptake.
EFFECT OF FROZEN STORAGE ON THE QUALITY ATTRIBUTES OF FRESH AND CONCENTRATE CUT-BACK STRAWBERRY JUICES

The present study was aimed to evaluate the effect of frozen storage at -18°C for 6 months on the quality attributes of the fresh and the concentrate Cut-back strawberry juices. The obtained results showed that the concentrate Cut-back strawberry juice was more acceptable by panelists. A significant decline in titratable acidity after freezing was observed in both types of strawberry juices; it decreased from 0.85 to 0.41 and from 0.98 to 0.49% for fresh strawberry juice and concentrate Cut-back juice, respectively. After 6 months of frozen storage similar tendency was observed for their vitamin C content having 9.45 and 29.23 mg/100ml for fresh and concentrate Cut-back strawberry juice, respectively. The pH increased from 3.805 to 4.340 and from 3.604 to 4.252 for fresh strawberry juice and concentrate Cut-back juice, respectively. The concentrated Cut-back strawberry juice prior to freezing was found to be rich in ferulic acid, resorcinol and quercetin being 10.09, 0.24 and 731.98 ppm which were by respectively compared to fresh strawberry juice. Quercetin was the dominant compound, it was the only one that found in the two juices after 6 months of frozen storage. While, kaempherol was appeared after freezing for the two types of juices and showed gradual increase by increasing the duration of frozen storage. The Cut-back strawberry juice showed higher antioxidant activity and viscosity than fresh juice. A slight decrease in viscosity was observed for the two types of juice after storage at -18°C for 6 months. The colour was not stable during the frozen storage at -18°C, The colour values increased in fresh strawberry juice for L*,a*and b* from 12.73, 21.00 and 7.77 to 16.89, 25.94 and 9.91, respectively, but in Cut-back strawberry juice the value of L* was only increased from 13.23 to13.55 while, a* and b* values decreased from 25.75 and 8.11 to 22.68 and 7.00, respectively. From results, it could be concluded that the Cut-back strawberry juice had the best quality after 6 months of frozen storage.
A Screening Instrument for Chronic Fatigue Syndrome: Reliability and Validity

AbstractBecause estimates of the prevalence of Chronic Fatigue Syndrome (CFS) have been quite variable, there is a need for a screening instrument and second stage medical assessment that will produce the most valid estimate of the CFS prevalence. In the present study, four groups of 15 subjects each were recruited: patients diagnosed with (1) CFS, (2) Lupus, (3) Multiple Sclerosis (MS), and (4) a healthy control group. Participants were interviewed twice over a two week period of time with a screening instrument comprising The Fatigue Scale and a newly configured section. The screening instrument had excellent test-retest and interrater reliability. This screening instrument therefore has utility for CFS community-based epidemiologic research. However, while the instrument differentiates patients with CFS from those who are healthy, it is less likely to distinguish CFS from other autoimmune diseases (especially Lupus). Thus, future community-based CFS prevalence studies should encompass both a screening .
Treatments for primary delusional infestation

Background Primary delusional infestation (DI) is a primary psychiatric disorder characterised by delusions and abnormal tactile sensations. The pathophysiology is undecided and treatment includes both pharmacological and non-pharmacological options. There is currently no Cochrane Review of the treatments used. Primary DI is a diagnosis often encountered by both dermatologists and psychiatrists, with a large associated disease burden. Objectives To evaluate the effectiveness of different treatments in primary delusional infestation (DI). Search methods On 24 December 2014 and 19 March 2019, we searched the Cochrane Schizophrenia Group's Study-Based Register of Trials including registries of clinical trials. Selection criteria Randomised controlled trials involving the treatment of adults with primary DI. Data collection and analysis Two review authors independently screened and assessed studies for inclusion using pre-specified inclusion criteria. Main results We did not identify any studies for inclusion. Authors' conclusions Currently there is no evidence from RCTs available to compare treatment of primary DI with placebo. We cannot, therefore, make any conclusions regarding the effects of treatments (pharmacological or non-pharmacological) for primary DI. This lack of evidence for treatment of primary DI has implications for research and practice. Robust randomised trials are indicated.
Analogs of Luteinizing Hormone-Releasing Hormone in the Treatment of Endometriosis

Agonists of luteinizing hormone-releasing hormone (LHRH) induce a reversible hypoestrogenic state through the down-regulation of LHRH receptors and desensitization of the pituitary. Since endometrial implants are estrogen sensitive, LHRH agonists have frequently been used for medical treatment of endometriosis. Nowadays, LHRH agonists can be considered in general as a second-line medical treatment for endometriosis-related symptoms, as oral therapy with dienogest is as effective and has fewer side effects. However, therapy with LHRH agonists for 3-6 months prior to in vitro fertilization remains the treatment of choice in patients with endometriosis, as it significantly increases pregnancy rates. LHRH agonists are used prior to surgery and as an adjuvant after an operation to prevent recurrence or prolong disease-free intervals. Adverse effects of LHRH agonists are due to hypoestrogenism and include hot flushes, vaginal dryness, loss of libido, sleep disturbances and a diminished bone density which limits the duration of their administration to 6 months. For long-term treatment, add-back of estrogen and/or progestin,/or progestin only with or without bisphosphonates, can be used, but existing studies only cover a 12-month period of treatment. LHRH antagonists competitively block the pituitary receptors for LHRH. Consequently, a partial pharmacological hypophysectomy with a reduction of the estrogen levels to a desired level is possible if LHRH antagonists are adequately dosed. As endometriotic implants require relatively high levels of estrogen, partially lower plasma levels of estrogens are sufficient to prevent the loss of bone density. A long-term treatment without add-back therapy is also possible.
Implementing Hospital Self-Management Policy in Chile: Health Professionals' Perceptions

Hospitals have been considered a main component for health systemssuccess. Objective: To describe perceptions from hospital staff regarding the implementationof the hospital self-management policy in two highly complex facilities in Chile. Justification:A successful policy implementation demands aligned health professionals regarding policychanges. Methods: Descriptive and exploratory qualitative study based on semi-structuredinterviews for health professionals from two hospitals in southern Chile. A convenience sampleof nineteen health professionals was selected for interviewing. The interviews’ analysis wasthought as the content analysis technique in its conventional approach. Results: For healthprofessionals, a hospital’s self-management policy is conceptualized from financial autonomy.Human resources for health and organizational capabilities still remain as weaknesses of theimplementation process. Conclusions: Overcoming gaps between design and implementationprocesses are crucial for success in hospital reform implementation.
Challenges Faced by Form Three Students at a Coeducational Denominational Secondary School, Regarding Their Access to Accurate Information About Topics as Outlined in the Sexuality and Sexual Health Component of the Health and Family Life Education Curriculum

Challenges Faced by Form Three Students at a Coeducational Denominational Secondary School, Regarding Their Access to Accurate Information About Topics as Outlined in the Sexuality and Sexual Health Component of the Health and Family Life Education Curriculum Alana Nalini Gajadhar This study investigated the challenges faced by three Form 3 students as they sought to access accurate information on topics outlined in the Sexuality and Sexual Health (SSH) component of the Health and Family Life Education curriculum at a coeducational denominational secondary school in Trinidad and Tobago. Data were collected through interviews. The findings revealed that, among other challenges, the students’ access to information was hampered by inadequate parental communication and insufficient information provided at school. Other barriers to access were: 1) their personal embarrassment, 2) their fear of being judged by others, 3) inaccurate sources of information, 4) superficial discussion of SSH topics, and 5) the lack of trust that their enquiries would be held in confidence.
Comparing the Effect of Teaching Using Educational Booklets and Lecture along with Educational Booklets on Nurses' Knowledge about Professional Laws and Regulations

Introduction: Learning professional laws and regulations are not achieved through traditional methods of education. The aim of this study was to present a new educational method for nurses concerning professional laws and regulations and compare the effect of this method on their knowledge. Methods: In this quasi-experimental study, 150 nurses employed in educational hospitals of Sari and Qaem-Shahr were selected randomly and matched in three groups of 50 based on education and position. A combination of two methods of booklet and lecture was used for the first group (experiment group), booklet method only was used for the second (experiment), and no intervention was done in third (control group). Pre-test was performed for the three groups before the study and, after three weeks, the post-test was held. A questionnaire was used for gathering data and the data was analyzed by SPSS software. Results: There was a significant difference between the mean scores, before and after education in the first group (experiment group). The difference in the knowledge score between the 2 experiment groups and the control group (after intervention) was confirmed. Also, the difference between the mean scores of the groups 1 and 2 as well as groups 1 and 3 was confirmed. The difference between the mean scores of the groups, based on age and working experience was statistically significant. Conclusion: Considering the increase in the mean scores of the first experiment group after education, it is recommended to employ the combination method (lecture and booklet) in educating nurses about professional laws and regulations.
Evidence-based Practices for young children with Autism Spectrum Disorders: Guidelines and recommendations from the National Resource Council and National Professional Development Center on Autism Spectrum Disorders

The National Research Council has identified goals, areas of need, and basic recommendations for educational programs serving children with autism spectrum disorders. The National Professional Development Center on Autism Spectrum Disorders has identified evidence-based practices for early childhood and elementary programming. Highlighting the work produced by these two organizations, this article provides professionals with guidance in setting up educational programs that use effective, research-based interventions for young children with autism spectrum disorders in early childhood special education.
Cutting Edge

Libraries and librarians are constructing a better world by experimenting with the latest technology for their patrons. As technologies evolve from time to time, new tools have been discovered to provide optimal services in minimal time. In developed countries like USA, UK, and Germany, the libraries are adopting new technologies for learning, research, and information to give the patron the best possible services. Librarians are struggling more to implement these cutting-edge technologies for learning, research, and information for their users.
Long-term effects of kinesthesia/balance and strengthening exercises on patients with knee osteoarthritis: A one-year follow-up study

Objective: Strengthening exercises are given frequently to the patients with knee osteoarthritis. It is known that these patients have proprioceptive deficits. The effect of the kinesthesia exercises which aim to improve proprioception is not known in the knee osteoarthritis. The aim was to compare kinesthetic plus strengthening exercises vs. strengthening exercise alone, and to determine the effects of these exercises on the pain and functional status of women with mild to moderate knee osteoarthritis (OA) in the long term. Methods: Sixty women with knee OA were included in the study. "Kinesthesia-strengthening group" performed kinesthe- sia/balance exercises as well as strengthening exercises, while the "strengthening group" performed only strengthening exercises. Patients were evaluated by Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC), Medical Outcomes Study Short Form Health Survey (SF-36), Lequesne algofunctional index, and Beck depression inventory. Results: After the completion of the exercises, significant improvements occurred in both the groups in all the study parameters ( p< 0.05). The comparison of the groups at week 8 showed that the results in SF-36 vitality, WOMAC-total score, Lequesne index and Beck depression inventory parameters in the kinesthesia-strengthening group were significantly better than those in the strengthening group ( p< 0.05). Similarly, the comparison of the groups at the end of year 1 demonstrated that the results in WOMAC-pain, WOMAC-stiffness, WOMAC-physical function and WOMAC-total score in the kinesthesia-strengthening group were significantly beter than those in the strengthening group ( p< 0.05). Conclusion: Carried out for one year, kinesthesia and balance exercises seem to be superior to strengthening exercises only on WOMAC parameters in women with mild to moderate knee OA.
Teaching on the Run – Learning on the Go

In an attempt to prepare students to meet the demand of the future workforce, and also to address the dropout crisis, educators are looking for new ways to integrate virtual worlds into the curricula. Digital economy finds its way to the tech-savvy youth. The number of computers, smartboards, and all kinds of widgets serving digital education are on the rise. Still, on the most part, our academic institutions continue to follow a 19th-century path based on rote learning and high-stakes testing. The paper intends to summarize some of the dominating notions that define the prevailing narratives of these issues. It also aims to explore the discrepancy between the imagined and the real learning environment while shedding light on the 2015 PISA results that show that technology alone will neither improve pupils' achievement nor will it help prepare them for the 21st-century labor market needs.
HOW dESTruCTivE SOCiAL ASpECTS iNHiBiT iNNOvATiON iN THE OrgANiSATiON

Background. The innovative behaviours of employees constitute one of the key elements for explaining companies’ market competitiveness. Therefore, studying and understanding the mechanisms which trigger individual innovative activity form an important area of analyses owing to which it is possible to design practical recommendations for managerial personnel of organisations. Research aims. Drawing on equity theory, this study describes and explains the relationship between counterproductive work behaviours (CWB), organisational justice and innovative workplace behaviours (IWB). In the proposed model explaining the influence of counterproductive work behaviours on creative activity in the workplace, the organisational justice construct was used – as the mediator of the relationship. Methodology. The study was conducted anonymously in 2014–2015 on a group of 207 employees studying at post-graduate studies at the Warsaw School of Economics. To assess the direct effects and estimation theoretical model, structural equation modelling was used with AMOS version 23. For the assessment of the indirect effects, the SPSS macro PROCESS was used, which allows for testing mediation effect. Correlation analyses weer also used. Key findings. The research confirmed a significant statistical relationship between innovative work behaviours and all studied variables: counterproductive work behaviours and organisational justice. On the basis of the analysis using the structural equation model it can be stated that the following factors influence innovative behaviours: counterproductive work behaviours have indirect influence on innovative workplace behaviours via organisational justice. The research shows that both organisational justice and counterproductive work behaviours provide a useful perspective which may facilitate understanding of the factors determining the occurrence of innovative activity in an organisation and may support creative behaviours of HRM and managers.