Miracle-dz/UniFAR-FTUs huggingface dataset:
Epidemic Rumination and Resilience on College Students' Depressive Symptoms During the COVID-19 Pandemic: The Mediating Role of Fatigue

The restriction of numerous sectors of society and the uncertainty surrounding the development of the COVID-19 pandemic have resulted in adverse psychological states to college students isolated at home. In this study, we explored the mediating role of fatigue in the effects of epidemic rumination and resilience on depressive symptoms as well as how epidemic rumination and resilience may interact with one another. A large sample of Chinese college students (N = 1,293) completed measures on epidemic rumination, resilience, fatigue, and depressive symptoms. Results indicated depressive symptomology was positively predicted by epidemic rumination while negatively predicted by resilience. In both cases, fatigue partially mediated these effects and positively predicted depressive symptoms. Unexpectedly, epidemic rumination and resilience interacted in a manner where the effect of rumination on fatigue became stronger as resiliency increased. Theoretical and practical implications are provided to further interpret the results.
A Systematic Review of Instruments to Assess Guilt in Children and Adolescents

Background: Guilt feelings have received considerable attention in past psychological theory and research. Several studies have been conducted that represent a range of views and propose various implications of guilt in children and adolescents. Variations in theoretical definitions of guilt, emphasizing a lack of measurement convergence, make it difficult to derive a comprehensive definition of the construct in childhood and adolescence. Research shows substantial variability in instruments used to measure guilt in children and adolescents. Purpose: The aim is to discuss existing contributions, illustrating the empirical validity of the available instruments used to measure guilt and identifying the nature of their theoretical backgrounds among children and adolescents. Methods: A systematic search was conducted using the following databases: PsycINFO, PsycARTICLES, MEDLINE, Scopus, Web of Science, and PubMed (all years up to February 19, 2020). Search terms were compiled into three concepts for all databases: “measure,” “guilt,” and “childhood/adolescence. ” In addition, a search was conducted to detect the gray literature. Results: After removing the duplicates, a total of 1,408 records were screened, resulting in the identification of 166 full-text articles to be further scrutinized. Upon closer examination, there was consensus that 148 of those studies met the study inclusion criteria or were not retrieved. Twenty-five studies were included in the quality assessment. The data were organized on three main categories: (1) interpersonal or prosocial guilt; (2) intrapunitive guilt or that referring to an excessive sense of responsibility; (3) not specifying a theoretical construct. A great heterogeneity in psychometric evaluations and substantial variability in guilt construct emerged. The construct most represented and supported by valid instruments was interpersonal or prosocial guilt. Analysis of the gray literature showed that some instruments were not immediately available to the clinical and scientific communities. Conclusions: The studies analyzed and selected for qualitative review employed various instruments to measure guilt. Results confirmed what is widely documented in the literature about substantial variability in instruments used to measure guilt. We argue the need to develop measures that assess currently overlooked dimensions of guilt and to provide further additional information about the psychometric proprieties of the available developed instruments.
Biofortification of Potato and Carrot With Iodine by Applying Different Soils and Irrigation With Iodine-Containing Water

Accumulation of iodine by potato (Solanum tuberosum L.) and carrot (Daucus carota L. var. sativus) plants cultivated on different soils (sand, sandy silt, and silt) using irrigation water containing iodine at concentrations of 0.1 and 0.5 mg/L was investigated. In the edible organs of potato and carrot control plants grown on sand, sandy silt, and silt soils, the iodine concentrations were 0.15, 0.17, and 0.20 mg/kg (potato) and 0.012, 0.012, and 0.013 mg/kg (carrot); after the treatment by applying 0.5 mg/L iodine dosage, the iodine concentrations were 0.21, 0.19, 0.27 mg/kg (potato) and 3.5, 3.7, 3.0 mg/kg (carrot), respectively. Although the iodine treatment had no significant effect on the biomass production of these plants, in potato tubers, it resulted in higher Fe and lower Mg and P concentrations, whereas no similar trend was observable in carrot roots. The accumulation of Mn, Cu, Zn, and B in the edible part of both plants was not influenced by the iodine treatment. The soil properties did not have a significant impact on biomass production under the same environmental conditions. The concentration and the distribution of iodine in both plants were slightly modified by the growing medium; however, the photosynthetic efficiency and the chlorophyll content index of potato plants cultivated in silt soil increased significantly. Potato plant was not suitable for biofortification with iodine, while considering the iodine concentration and the moisture content of carrot roots, it can be calculated that consuming 100 g fresh carrot would cover about 38% of the daily iodine intake requirement for an average adult person.
The Mycotoxin Deoxynivalenol (DON) Promotes Campylobacter jejuni Multiplication in the Intestine of Broiler Chickens With Consequences on Bacterial Translocation and Gut Integrity

Deoxynivalenol (DON) is one of the major health concern in poultry production as it targets epithelial cells of the gastrointestinal tract and contributes to the loss of the epithelial barrier function. It is well-documented that DON severely compromises various important intestinal functions in coincidence with aggravated clinical symptoms in livestock. In addition, a prolonged persistence of intestinal pathogens (e.g., Salmonella, Clostridium) in the gut has also been reported in pigs and chickens, respectively. Similar to DON, recent studies demonstrated that an experimental Campylobacter infection has severe consequences on gut health. Through experimental infection, it was found that Campylobacter (C.) jejuni negatively affects the integrity of the intestine and promotes the translocation of bacteria from the gut to inner organs. So far, no data are available investigating the simultaneous exposure of DON and C. jejuni in broilers albeit both are widely distributed. Thus, the aim of the present study was to explore the interaction between DON and C. jejuni which is of a significant public and animal health concern as it may affect the prevalence and the ability to control this pathogen. Following oral infection of birds at 14 days of age with C. jejuni NCTC 12744, we show that the co-exposure to DON and C. jejuni has a considerable consequence on C. jejuni loads in chicken gut as well as on gut permeability of the birds. A reduced growth performance was found for DON and/or C. jejuni exposed birds. Furthermore, it was found that the co-exposure of DON and C. jejuni aggravated the negative effect on paracellular permeability of the intestine already noticed for the bacteria or the mycotoxin alone by the Ussing chamber technique at certain times or intestinal segments. Furthermore, the increased paracellular permeability promotes the translocation of C. jejuni and E. coli to inner organs, namely liver and spleen. Interestingly, C. jejuni loads in the intestine were higher in DON-fed groups indicating a supportive growth effect of the mycotoxin. The actual study demonstrates that co-exposure of broiler chickens to DON and C. jejuni has not only considerable consequences on gut integrity but also on bacterial balance. These findings indicate that the co-exposure of broiler chickens to DON and C. jejuni could have a significant impact on gut health and bacteria translocation leading to an increased risk for public health.
Alteração em características químicas de um solo ácido pela aplicação de calcário e resíduos de reciclagem de papel

O processo de reciclagem de papel gera residuos que sao geralmente depositados em aterros. No entanto, esses residuos apresentam constituintes que podem atuar como corretivos da acidez do solo e como fonte de nutrientes, principalmente o calcio. Por outro lado, nesses residuos tambem ha presenca de metais pesados, que podem causar impacto ambiental negativo. O objetivo desse trabalho foi avaliar o efeito de doses de calcario dolomitico e de dois tipos de residuo de industria que recicla papel sobre o pHagua; pHSMP; teores de P, K, M.O. , Al, Ca, Mg, Al+H; CTC; saturacao por bases e por Al; relacao Ca/Mg; e teores de S, Zn, Cu, B, Mn, Fe, Hg, Pb, Ni, Cd e Cr. O calcario e os residuos de reciclagem de papel corrigiram a acidez do solo, bem como alteraram significativamente outras caracteristicas quimicas. Os teores de K no solo foram reduzidos pela aplicacao dos residuos. A aplicacao de residuos de reciclagem de papel nao aumentou os teores de metais pesados no solo.
Applicability of an Active Back-Support Exoskeleton to Carrying Activities

Occupational back-support exoskeletons are becoming a more and more common solution to mitigate work-related lower-back pain associated with lifting activities. In addition to lifting, there are many other tasks performed by workers, such as carrying, pushing, and pulling, that might benefit from the use of an exoskeleton. In this work, the impact that carrying has on lower-back loading compared to lifting and the need to select different assistive strategies based on the performed task are presented. This latter need is studied by using a control strategy that commands for constant torques. The results of the experimental campaign conducted on 9 subjects suggest that such a control strategy is beneficial for the back muscles (up to 12% reduction in overall lumbar activity), but constrains the legs (around 10% reduction in hip and knee ranges of motion). Task recognition and the design of specific controllers can be exploited by active and, partially, passive exoskeletons to enhance their versatility, i.e., the ability to adapt to different requirements.
Transformer-based Double-token Bidirectional Autoregressive Decoding in Neural Machine Translation

This paper presents a simple method that extends a standard Transformer-based autoregressive decoder, to speed up decoding. The proposed method generates a token from the head and tail of a sentence (two tokens in total) in each step. By simultaneously generating multiple tokens that rarely depend on each other, the decoding speed is increased while the degradation in translation quality is minimized. In our experiments, the proposed method increased the translation speed by around 113%-155% in comparison with a standard autoregressive decoder, while degrading the BLEU scores by no more than 1.03. It was faster than an iterative non-autoregressive decoder in many conditions.
Supporting Female Survivors of Gender-Based Violence Experiencing Homelessness: Outcomes of a Health Promotion Psychoeducation Group Intervention

Homelessness is an important risk factor for gender-based violence (GBV), particularly among youth, and disproportionally affects women and girls. Survivors of GBV experience enduring and severe physical, psychological, and sexual health problems. Although key elements in service delivery for survivors of GBV have been identified, little is known about outcomes of community-based programs aiming to assist homeless and unstably housed youth experiencing GBV. This longitudinal study aimed to quantitatively evaluate changes in mental health and well-being outcomes in female identified youth experiencing GBV and homelessness, 12 months after enrolment in a community-based, trauma-informed, brief group psychoeducation intervention. Standardized survey measures were administered at baseline, 6 and 12 months for 70 participants, recruited between February 2017 and April 2019, assessing quality of life, psychological distress, traumatic symptoms, substance use, resilience, victimization, and sense of mastery. Linear mixed models were used to examine longitudinal changes in quality of life as well as secondary outcomes among study participants. After 12 months, quality of life increased significantly among participants (p = 0.009), and the 12-month victimization score was significantly decreased relative to baseline (p = 0.05). Changes in other outcomes were not statistically significant. Findings suggest that community-based brief group psychoeducation interventions may be a promising approach to improving outcomes for this disadvantaged population.
Teacher Roles in Personalized Learning Environments

As school districts, major cities, and entire states in the United States adopt personalized learning as a reform strategy focused on the co-construction of learning opportunities between teachers and students, educators face shifting roles. This study examined the roles of teachers in personalized learning environments within a policy context of statewide legislation of personalized learning plans, flexible educational pathways, and proficiency-based assessment. The study used data from interviews with a purposefully selected group of 20 elementary and middle school teachers from 11 schools. Findings revealed teachers’ perceptions of their roles as (a) empowerers, (b) scouts, (c) scaffolders, and (d) assessors, as well as associated strategies within each role that participants perceived to be constructive. The use of role theory illuminated the potential for intrarole conflict and role strain between and among these roles along with the cultural dimensions of the shift to personalized learning.
Reverse Engineering Targets for Recombinant Protein Production in Corynebacterium glutamicum Inspired by a Fast-Growing Evolved Descendant

We previously reported a Corynebacterium glutamicum JH41 strain with a 58% faster growth rate through application of adaptive laboratory evolution. To verify that the fast-reproducing strain was useful as a host for recombinant protein expression, we introduced a plasmid responsible for the secretory production of a recombinant protein. The JH41 strain harboring the plasmid indeed produced the secretory recombinant protein at a 2.7-fold greater rate than its ancestral strain. To provide the reverse engineering targets responsible for boosting recombinant protein production and cell reproduction, we compared the genome sequence of the JH41 strain with its ancestral strain. Among the 15 genomic variations, a point mutation was confirmed in the 14 bases upstream of NCgl1959 (encoding a presumed siderophore-binding protein). This mutation allowed derepression of NCgl1959, thereby increasing iron consumption and ATP generation. A point mutation in the structural gene ramA (A239G), a LuxR-type global transcription regulator involved in central metabolism, allowed an increase in glucose consumption. Therefore, mutations to increase the iron and carbon consumption were concluded as being responsible for the enhanced production of recombinant protein and cell reproduction in the evolved host.
Anthropogenic CO2 of High Emission Scenario Compensated After 3500 Years of Ocean Alkalinization With an Annually Constant Dissolution of 5 Pg of Olivine

The CO2 removal model inter-comparison (CDRMIP) has been established to approximate the usefulness of climate mitigation by some well-defined negative emission technologies. I here analyze ocean alkalinization in a high CO2 world (emission scenario SSP5-85-EXT++ and CDR-ocean-alk within CDRMIP) for the next millennia using a revised version of the carbon cycle model BICYCLE, whose long-term feedbacks are calculated for the next 1 million years. The applied model version not only captures atmosphere, ocean, and a constant marine and terrestrial biosphere, but also represents solid Earth processes, such as deep ocean CaCO3 accumulation and dissolution, volcanic CO2 outgassing, and continental weathering. In the applied negative emission experiment, 0.14 Pmol/yr of alkalinity—comparable to the dissolution of 5 Pg of olivine per year—is entering the surface ocean starting in year 2020 for either 50 or 5000 years. I find that the cumulative emissions of 6,740 PgC emitted until year 2350 lead to a peak atmospheric CO2 concentration of nearly 2,400 ppm in year 2326, which is reduced by only 200 ppm by the alkalinization experiment. Atmospheric CO2 is brought down to 400 or 300 ppm after 2730 or 3480 years of alkalinization, respectively. Such low CO2 concentrations are reached without ocean alkalinization only after several hundreds of thousands of years, when the feedbacks from weathering and sediments bring the part of the anthropogenic emissions that stays in the atmosphere (the so-called airborne fraction) below 4%. The efficiency of carbon sequestration by this alkalinization approach peaks at 9.7 PgC per Pmol of alkalinity added during times of maximum anthropogenic CO2 emissions and slowly declines to half this value 2000 years later due to the non-linear marine chemistry response and ocean-sediment processes. In other words, ocean alkalinization sequesters carbon only as long as the added alkalinity stays in the ocean. To understand the basic model behavior, I analytically explain why in the simulation results a linear relationship in the transient climate response (TCR) to cumulative emissions is found for low emissions (similarly as for more complex climate models), which evolves for high emissions to a non-linear relation.
A Systematic Review and Meta-Analysis of Health Utility Estimates in Chronic Spontaneous Urticaria

Background: Chronic spontaneous urticaria (CSU) is a common recurrent skin disease that adversely affect patient's quality of life condition to treat. Economic evaluations of health care often include patient preferences for health outcomes using utilities. Objectives: The study aimed to determine pooled estimates of utility-based quality of life in patients with CSU. Methods: We conducted a systematic review, meta-analysis, and meta-regression of peer-reviewed articles and conference papers that published from database inception to 31 April 2019 that reported utility estimates in patients with CSU. Scores reported with the EQ-5D, SF-6D, SF-12, and SF-36 instruments were converted to utilities using published mapping algorithms. Meta-analysis was used to calculate the pooled and meta-regression was used to examine the effects of possible factors. Results: The pooled utility estimate for CSU was 0.68 [95% confidence interval (CI): 0.67–0.70]. The pooled utility estimate that converted from SF-36 or SF-12 was 0.66 (95% CI: 0.58–0.74), 0.72 (95% CI: 0.70–0.74) for EQ-5D, and 0.65 (95% CI: 0.63–0.67) for SF-6D, respectively. According to the meta-regression, higher proportion of female patients was significantly associated lower utility estimates (p = 0.013). Conclusions: The study provides evidence-based utility estimates to inform health-related burden analysis of CSU and reference for the follow-up cost-effectiveness evaluation of chronic spontaneous urticaria intervention. These results highlight differences in common utility-based instruments and need to be cognizant of the specific instruments used when comparing the results of outcome studies.
Biomaterials in Valvular Heart Diseases

Valvular heart disease (VHD) occurs as the result of valvular malfunction, which can greatly reduce patient’s quality of life and if left untreated may lead to death. Different treatment regiments are available for management of this defect, which can be helpful in reducing the symptoms. The global commitment to reduce VHD-related mortality rates has enhanced the need for new therapeutic approaches. During the past decade, development of innovative pharmacological and surgical approaches have dramatically improved the quality of life for VHD patients, yet the search for low cost, more effective, and less invasive approaches is ongoing. The gold standard approach for VHD management is to replace or repair the injured valvular tissue with natural or synthetic biomaterials. Application of these biomaterials for cardiac valve regeneration and repair holds a great promise for treatment of this type of heart disease. The focus of the present review is the current use of different types of biomaterials in treatment of valvular heart diseases.
Efficient Amplification in Soai's Asymmetric Autocatalysis by a Transient Stereodynamic Catalyst

Mechanisms leading to a molecular evolution and the formation of homochirality in nature are interconnected and a key to the underlying principles that led to the emergence of life. So far proposed mechanisms leading to a non-linear reaction behavior are based mainly on the formation of homochiral and heterochiral dimers. Since homochiral and heterochiral dimers are diastereomers of each other, the minor enantiomer is shifted out of equilibrium with the major enantiomer by dimer formation and thus a reaction or catalysis can be dominated by the remaining molecules of the major enantiomer. In this article a mechanism is shown that leads to homochirality by the formation of a highly catalytically active transient intermediate in a stereodynamically controlled reaction. This is demonstrated by Soai's asymmetric autocatalysis, in which aldehydes are transformed into the corresponding alcohols by addition of dialkylzinc reagents. The mechanism of chirogenesis proposed here shows that an apparently inefficient reaction is the best prerequisite for a selection mechanism. In addition, stereodynamic control offers the advantage that the minor diastereomeric intermediate can be interconverted into the major diastereomer and thus be stereoeconomically efficient. This is supported by computer simulation of reaction kinetics.
HW-TSC’s Participation in the WAT 2020 Indic Languages Multilingual Task

This paper describes our work in the WAT 2020 Indic Multilingual Translation Task. We participated in all 7 language pairs (En<->Bn/Hi/Gu/Ml/Mr/Ta/Te) in both directions under the constrained condition—using only the officially provided data. Using transformer as a baseline, our Multi->En and En->Multi translation systems achieve the best performances. Detailed data filtering and data domain selection are the keys to performance enhancement in our experiment, with an average improvement of 2.6 BLEU scores for each language pair in the En->Multi system and an average improvement of 4.6 BLEU scores regarding the Multi->En. In addition, we employed language independent adapter to further improve the system performances. Our submission obtains competitive results in the final evaluation.