Miracle-dz/UniFAR-FTUs huggingface dataset:
Validation of a Complementary Food Frequency Questionnaire to assess infant nutrient intake

Abstract Dietary assessment in infants is challenging but necessary to understand the relationship between nutrition and growth and development. Currently no simple, validated methods exist to assess nutrient intake in New Zealand (NZ) infants. Therefore, this study aimed to assess the relative validity and reproducibility of a Complementary Food Frequency Questionnaire (CFFQ) to determine nutrient intakes of NZ infants. Ninety‐five parent–infant pairs (infant age 10 ± 1 months) completed the CFFQ twice (CFFQ‐1 and CFFQ‐2), 4 weeks apart (to assess reproducibility). A 4‐day weighed food record (4dWFR) was collected between CFFQ administrations (to assess validity). Validity and reproducibility were assessed for intakes of energy and 18 nutrients using Bland–Altman analysis, Pearson's correlation coefficients, cross‐classification, and weighted Kappa (κ). The CFFQ showed acceptable validity: Nutrients from the CFFQ were comparable with the 4dWFR (bias, 9–28%), correlation between methods ranged from r = . 18 (saturated fat) to r = . 81 (iron; mean r = .52), 54% (mean) of participants were correctly classified (range 39% to 67%), and 7.1% (mean) misclassified into opposite tertiles (range 2.1% to 14.7%). There was acceptable agreement between the CFFQ and 4dWFR (κ = 0.20–0.60). The CFFQ showed good reproducibility: Correlations ranged from r = . 34 (folate) to r = . 80 (zinc); for 16 nutrients, >50% of participants were correctly classified, and for all nutrients, <10% of participants were grossly misclassified. All nutrients showed acceptable to good agreement (κ > 0.20). The CFFQ has acceptable relative validity and good reproducibility for assessing nutrient intake in NZ infants aged 9–12 months, making it a useful tool for use in future research.
Using SAS to Manage Biological Species Data and Calculate Diversity Indices

Species level information is necessary for conservation, management, and research into ecological and environmental systems. A common problem is that one doesn’t know what the community composition will be, so data management is complex because it has to be managed by species and not by samples. Once the data management problem is solved, there will be a need to summarize information at the sample level, and perhaps calculate a diversity index. This presentation will describe algorithms for commonly used diversity indices, and demonstrate how SAS was used to solve the data management and computational problems.
Eight Weeks of a High Dose of Curcumin Supplementation May Attenuate Performance Decrements Following Muscle-Damaging Exercise

Background: It is known that unaccustomed exercise—especially when it has an eccentric component—causes muscle damage and subsequent performance decrements. Attenuating muscle damage may improve performance and recovery, allowing for improved training quality and adaptations. Therefore, the current study sought to examine the effect of two doses of curcumin supplementation on performance decrements following downhill running. Methods: Sixty-three physically active men and women (21 ± 2 y; 70.0 ± 13.7 kg; 169.3 ± 15.2 cm; 25.6 ± 14.3 body mass index (BMI), 32 women, 31 men) were randomly assigned to ingest 250 mg of CurcuWIN® (50 mg of curcuminoids), 1000 mg of CurcuWIN® (200 mg of curcuminoids), or a corn starch placebo (PLA) for eight weeks in a double-blind, randomized, placebo-controlled parallel design. At the end of the supplementation period, subjects completed a downhill running protocol intended to induce muscle damage. Muscle function using isokinetic dynamometry and perceived soreness was assessed prior to and at 1 h, 24 h, 48 h, and 72 h post-downhill run. Results: Isokinetic peak extension torque did not change in the 200-mg dose, while significant reductions occurred in the PLA and 50-mg groups through the first 24 h of recovery. Isokinetic peak flexion torque and power both decreased in the 50-mg group, while no change was observed in the PLA or 200-mg groups. All the groups experienced no changes in isokinetic extension power and isometric average peak torque. Soreness was significantly increased in all the groups compared to the baseline. Non-significant improvements in total soreness were observed for the 200-mg group, but these changes failed to reach statistical significance. Conclusion: When compared to changes observed against PLA, a 200-mg dose of curcumin attenuated reductions in some but not all observed changes in performance and soreness after completion of a downhill running bout. Additionally, a 50-mg dose appears to offer no advantage to changes observed in the PLA and 200-mg groups.
Precision Cancer Nanotherapy: Evolving Role of Multifunctional Nanoparticles for Cancer Active Targeting.

Nanoparticles with multifunctionality are being designed and formulated to overcome various limitations of drugs as well as conventional drug delivery systems. Engineered nanoparticles to specifically target cancer cells have the ability to reduce collateral damage on normal tissue due to pan-toxic effects of drugs. Pragmatic approaches are being in consideration to make advancement in cancer therapy as the new developed methods exhibited an improved targeted anticancer therapeutic delivery with better treatment outcomes. An effective cancer therapy requires both the passive and active targeting to successfully achieve targeted delivery. The nanoparticles can be conjugated with specific ligands, antibodies and carbohydrates for active targeting of cancer cells with great affinity and precision. This review presents some recent strategies such as immunotherapy, role of cell sex and protein corona in for targeted cancer therapy and also discusses some examples of engineered nanoparticles exploited for active cancer targeting and their limitations and associated toxicity.
Telephone-Based Coaching and Prompting for Physical Activity: Short- and Long-Term Findings of a Randomized Controlled Trial (Movingcall)

This study analyzed the short- and long-term efficacy of telephone coaching and short message service (SMS) prompting for physical activity (PA) promotion. Two-hundred-and-eighty-eight adults (age: 42 ± 11 years) were assigned randomly to three intervention arms: The intervention groups received 12 bi-weekly telephone calls with (coaching and SMS group) or without (coaching group) additional SMS prompts (n = 48 SMS). The control group received a single written PA recommendation. Self-reported and objective moderate-to-vigorous physical activity (MVPA) levels were assessed by a structured interview and by accelerometer at baseline, after the intervention (6 months), as well as after a no-contact follow-up (12 months). At post-test, self-reported MVPA increased by 173 min/week (95% CI 95 to 252) in the coaching group and by 165 min/week (95% CI 84 to 246) in the coaching and SMS group compared to control. These group differences remained similar in the follow-up test. For the objectively assessed MVPA, the coaching group increased by 32 min/week (95% CI 0.1 to 63) and the coaching and SMS group by 34 min/week (95% CI 1.6 to 66) compared to the control group. In the follow-up test, the objective MVPA levels of the intervention groups no longer differed from baseline, but group differences persisted as the control group decreased below baseline. Additional SMS prompts did not result in a further increase in PA. Telephone coaching can be considered an effective tool for PA promotion.
The role of component-resolved diagnosis in Hymenoptera venom allergy.

PURPOSE OF REVIEW Component-resolved diagnostics (CRD) is a new tool aiming at detecting IgE-mediated sensitizations against individual, relevant allergens. Here, we discuss recent literature on molecular diagnosis in the field of Hymenoptera venom allergy (HVA) as well as CRD strengths and weaknesses. RECENT FINDINGS CRD, using single molecules or panels of allergens, may discriminate between primary sensitization and cross-reactivity in patients with double/multiple positivity in diagnostic tests with whole extracts, allowing the specialist to choose the most suitable venom for specific immunotherapy (VIT), avoiding unnecessary VIT and reducing the risk of side effects. Future availability of the cross-reactive recombinant pairs of allergens of different species may further increase the diagnostic performance. CRD may be useful in patients with negative allergy tests and a proven history of a previous systemic reaction, including those with mast cell disorders, who could benefit from VIT. In honeybee venom allergy, different sensitization profiles have been identified, which could be associated with a greater risk of VIT failure or treatment side effects. SUMMARY CRD is undoubtedly an innovative diagnostic method that leads to a more precise definition of the sensitization profile of the HVA patient. Together with a better knowledge of the molecular composition of different venom extracts, CRD may contribute to optimize patient-tailored therapy.
A Survey on Data Clustering Algorithms

Clustering is a technique adapted in many real world applications. Generally clustering can be thought of as partitioning the data into group or subsets, which contain analogous objects. A lot of clustering techniques like K-Means algorithm, Fuzzy C-Means algorithm (FCM), spectral clustering algorithm and so on has been proposed earlier in literature. Recently, clustering algorithms are extensively used for mixed data types to evaluate the performance of the clustering techniques. This paper presents a survey on various clustering algorithms that are proposed earlier in literature. Moreover it provides an insight into the advantages and limitations of some of those earlier proposed clustering techniques. The comparison of various clustering techniques is provided in this paper. The future enhancement section of this paper provides a general idea for improving the existing clustering algorithms to achieve better clustering accuracy.
MATLAB Simulation for Speed Control of Three Phase Induction Motor Drive using V/FControl

As the subject of the paper, the speed control of induction motor fed by a three phase voltage source inverter has been done using PWM. To control the peak dc link voltage of the VSI, a PI controller was designed. This model uses the bode diagram. Based on the required dynamic specifications, the parameters of the PI controller were calculated. The speed control method adopted was compared with the adjustable speed drives. The comparison was done to change the motor speed from 0 to the rated speed (N s ) with the rated load torque. MATLAB simulation of the proposed speed control method for 1HP induction motor was done to verify the performance of the proposed method.
A low-complexity region in human XRN1 directly recruits deadenylation and decapping factors in 5′–3′ messenger RNA decay

Abstract XRN1 is the major cytoplasmic exoribonuclease in eukaryotes, which degrades deadenylated and decapped mRNAs in the last step of the 5′–3′ mRNA decay pathway. Metazoan XRN1 interacts with decapping factors coupling the final stages of decay. Here, we reveal a direct interaction between XRN1 and the CCR4–NOT deadenylase complex mediated by a low-complexity region in XRN1, which we term the ‘C-terminal interacting region’ or CIR. The CIR represses reporter mRNA deadenylation in human cells when overexpressed and inhibits CCR4–NOT and isolated CAF1 deadenylase activity in vitro. Through complementation studies in an XRN1-null cell line, we dissect the specific contributions of XRN1 domains and regions toward decay of an mRNA reporter. We observe that XRN1 binding to the decapping activator EDC4 counteracts the dominant negative effect of CIR overexpression on decay. Another decapping activator PatL1 directly interacts with CIR and alleviates the CIR-mediated inhibition of CCR4–NOT activity in vitro. Ribosome profiling revealed that XRN1 loss impacts not only on mRNA levels but also on the translational efficiency of many cellular transcripts likely as a consequence of incomplete decay. Our findings reveal an additional layer of direct interactions in a tightly integrated network of factors mediating deadenylation, decapping and 5′–3′ exonucleolytic decay.
Palestinian Women in Terrorism: A Double-Edged Sword?

Drawing on a decade of research on terrorism in the Israeli–Palestinian conflict, we show how subjective “rational choices” motivate some women to engage in terrorist activism. Focusing on the motives of young women who engage in terrorism is consistent with feminist theory’s insistence on women’s agency—even at the extremes. In addition to the well-established motivations for terrorism reported in the literature, interviews with young women involved in terrorism reveal mixed personal motives for their gender-defying choices, including thrill-seeking and some conscious rebellion. However, we contend that women’s subjective rationale for participation in such violent behavior needs to be contextualized. A cost–benefit approach, we maintain, highlights the strategic considerations supporting the deployment of women as combatants by Palestinian terrorist organizations. We argue that the inclusion of women in terrorist activism in the Israeli–Palestinian conflict exposes a major fault line in attitudes to the role and proper place of women in what remains largely a patriarchal culture. This social ambivalence accounts for why, on all measures, women fare worse than their male counterparts. The implications of the findings for feminist research as well as policy are discussed.
An Energy-Saving Privacy-Preserving Data Aggregation Algorithm

Privacy preserving plays an important role in application of the Internet of Things(IoT). As a part of the IoT,Wireless Sensor Networks(WSNs) should provide the privacy preserving in data aggregation.This paper presents a novel energy-saving private-preserving aggregation scheme(ESPART) for WSNs,which uses characteristic of the data aggregation tree structure to reduce communication overhead,assigns the random time pieces to nodes to avoid collision,and limits the scope of collusion data to reinforce data_loss resilience.Compared with the SMART algorithm,the simulation results show that ESPART can preserve data privacy,get accurate data aggregation results while taking the same epoch duration as TAG,and have less communication overhead.
Oxford American dictionary and thesaurus

For anyone who has ever spent time going back and forth from the thesaurus to the dictionary, in search of just the right word, the Oxford American Dictionary & Thesaurus is the perfect tool-an all-in-one desk reference offering the range and depth of a full dictionary, with a wide selection of synonyms and antonyms, plus valuable writing tips and information-all combined in one convenient, integrated volume. The Second Edition contains more than 150,000 words, phrases and definitions - twice as many as the competition - plus approximately 184,000 synonyms and antonyms. More important, the new edition now completely integrates the dictionary and thesaurus text, with the synonyms and antonyms directly following the dictionary definitions of their related part of speech. The new edition also boasts a fresh redesign of the interior, featuring an open, well-spaced layout and a more readable type, with the thesaurus sections clearly differentiated from the dictionary text for optimal clarity and usability. To accompany this fresh design, the book includes more than seventy pages of entirely revised supplementary material, including Usage Notes, Word Links, Choose the Right Word boxes, Word Toolkits, thematic lists, US/British equivalents, and a grammar guide - seamlessly blended into the principle text. And finally, many new headwords and example sentences have been added and the text has been revised throughout. With definitions and synonyms grouped together, writers can now know instantly if a particular word is the one that best captures what they want to say. Authoritative, up to date, and attractively redesigned, the second edition of the Oxford American Dictionary & Thesaurus is an essential resource for students, writers, and anyone else who wants to write clearly, precisely, and with power.
B-Mode Ultrasound Findings in a Patient With Suspected Pulmonary Gangrene.

OBJECTIVES Lung ultrasound has shown increasing diagnostic value in many lung diseases and has become an efficient tool in the management of dyspnea. In the present case report, we describe a new ultrasound feature of potential interest. DATA SOURCES Clinical observation of a patient. STUDY SELECTION Case report. DATA EXTRACTION Data were extracted from medical records, after obtaining consent from the patient's family. Illustrations were extracted from the imaging software and a video device. DATA SYNTHESIS A 56-year-old man was admitted with pneumonia of adverse outcome. Lung ultrasound, a method increasingly considered as a bedside gold standard in critically ill patients due to its overwhelming advantages, was the only tool able to specify the lung injuries. We describe herein a distinctive sign unequivocally evoking a destructive process suggestive of pulmonary gangrene, a variant of the fractal sign combining a lung consolidation with an underlying heterogeneous free fluid. CONCLUSIONS Lung ultrasound may help highlight pulmonary gangrene, a poorly-known disease, with this new ultrasonographic description. The next step will be to ascertain the relation between this new ultrasound feature and pulmonary gangrene and to assess how this bedside diagnosis could impact the prognosis of the disease.
The Traditional Ordinary Least Squares Estimator under Collinearity

In a multiple regression analysis, it is usually difficult to interpret the estimator of the individual coefficients if the explanatory variables are highly inter-correlated. Such a problem is often referred to as the multicollinearity problem. There exist several ways to solve this problem. One such way is ridge regression. Two approaches of estimating the shrinkage ridge parameter k are proposed. Comparison is made with other ridge-type estimators. To investigate the performance of our proposed methods with the traditional ordinary least squares (OLS) and the other approaches for estimating the parameters of the ridge regression model, we calculate the mean squares error (MSE) using the simulation techniques. Results of the simulation study shows that the suggested ridge regression outperforms both the OLS estimator and the other ridge-type estimators in all of the different situations evaluated in this paper.
Frog Virus 3 Genomes Reveal Prevalent Recombination between Ranavirus Lineages and Their Origins in Canada

Amphibian populations are declining worldwide, and these declines have been linked to a number of anthropogenic factors, including disease. Among the pathogens associated with amphibian mortality, ranaviruses have caused massive die-offs across continents. In North America, frog virus 3 (FV3) is a widespread ranavirus that can infect wild and captive amphibians. In this study, we sequenced full FV3 genomes isolated from frogs in Canada. We report widespread recombination between FV3 and common midwife toad virus (CMTV). Phylogenies indicate a recent origin for FV3 in Canada, possibly as a result of international amphibian trade. ABSTRACT Ranaviruses are pathogens associated with the decline of amphibian populations across much of their distribution. In North America, frog virus 3 (FV3) is a widely distributed pathogen with wild populations of amphibians harboring different lineages and putative recombinants between FV3 and common midwife toad virus (CMTV). These recombinants have higher pathogenicity, and CMTV-derived genes associated with virulence are reported in wild strains in Canada. However, while FV3 is linked to amphibian die-offs in North America, CMTVs have been reported only in commercial frog farms in North America. We sequenced complete genomes of 18 FV3 isolates from three amphibian species to characterize genetic diversity of the lineages in Canada and infer possible recombinant regions. The 18 FV3 isolates displayed different signals of recombination, varying from none to interspersed recombination with previously isolated CMTV-like viruses. In general, most recombination breakpoints were located within open reading frames (ORFs), generating new ORFs and proteins that were a mixture between FV3 and CMTV. A combined spatial and temporal phylogeny suggests the presence of the FV3 lineage in Canada is relatively contemporary (<100 years), corroborating the hypothesis that both CMTV- and FV3-like viruses spread to North America when the international commercial amphibian trade started. Our results highlight the importance of pathogen surveillance and viral dynamics using full genomes to more clearly understand the mechanisms of disease origin and spread. IMPORTANCE Amphibian populations are declining worldwide, and these declines have been linked to a number of anthropogenic factors, including disease. Among the pathogens associated with amphibian mortality, ranaviruses have caused massive die-offs across continents. In North America, frog virus 3 (FV3) is a widespread ranavirus that can infect wild and captive amphibians. In this study, we sequenced full FV3 genomes isolated from frogs in Canada. We report widespread recombination between FV3 and common midwife toad virus (CMTV). Phylogenies indicate a recent origin for FV3 in Canada, possibly as a result of international amphibian trade.
Human Bone Marrow Mesenchymal Stem Cell Conditioned Medium Promotes Wound Healing in Deep Second-Degree Burns in Male Rats

Burn wound treatment is difficult and one of the most challenging problems in the clinic. Researchers have examined the applications of mesenchymal stem cells as a cell-based therapy for skin regeneration. But the role of human bone marrow mesenchymal stem cell conditioned medium (hBM-MSC-CM) in the treatment of burn injury remains unclear. This research aims at detecting whether hBM-MSC-CM can increase the wound healing of deep second-degree burns in male rats. In this study, 32 adult male rats per each time point were randomly divided into four groups: (1) control group, (2) sham group (DMEM), (3) common treatment group (CT), and (4) conditioned media group (CM). A 3 × 3 cm circular burn was created on the back of the rats. On postsurgical days 7, 15, and 28, the wound closure area of each wound was measured and then the skin samples were removed and analyzed using stereological methods. Wound closure area was significantly increased in the CM and CT groups on the 15th and the 28th day after burn injury compared to the control and DMEM groups. The stereological parameters and immunohistochemistry analysis of the wounds revealed significantly improved healing in the CM group compared to the control and other groups. It is concluded that these findings indicate that hBM-MSC-CM promotes skin wound healing by increasing cell proliferation, regulating collagen synthesis and collagen composition, and inducing angiogenesis at the injury site.
Photovoltaic Sources Modeling

This comprehensive guide surveys all available models for simulating a photovoltaic (PV) generator at different levels of granularity, from cell to system level, in uniform as well as in mismatched conditions. Providing a thorough comparison among the models, engineers have all the elements needed to choose the right PV array model for specific applications or environmental conditions matched with the model of the electronic circuit used to maximize the PV power production.