Miracle-dz/UniFAR-FTUs huggingface dataset:
Features for analysis of Makam music

For computational studies of makam music, it is essential to gather a list of characteristics that constitute a makam and explore corresponding quantitative features for automatic analysis. This study is such an attempt where we address the characteristics for makams as defined in theory books and deduce a list of quantitative features. The target here is to evoke discussions on some measurable features other than providing complete analysis on the discriminative potentials of each proposed feature which could be the subject of a few larger studies.
Nano- and Microstructures for Thin-Film Evaporation—A Review

Evaporation from thin films is a key feature of many processes, including energy conversion, microelectronics cooling, boiling, perspiration, and self-assembly operations. The phase change occurring in these systems is governed by transport processes at the contact line where liquid, vapor, and solid meet. Evidence suggests that altering the surface chemistry and surface topography on the micro- and the nanoscales can be used to dramatically enhance vaporization. The 2013 International Workshop on Micro- and Nanostructures for Phase-Change Heat Transfer brought together a group of experts to review the current state-of-the-art and discuss future research needs. This article is focused on the thin-film evaporation panel discussion and outlines some of the key principles and conclusions reached by that panel and the workshop attendees.
Food Texture Profile Analysis by Compression Test

Firmness is a principal mechanical characteristic for the consumer when eating different solid foods. However, rheological parameters, such as the viscous, elastic and plastic characters of foods are of importance, as well. Compression tests are suitable for determining several mechanical and rheological characteristics of different foods with special respects to consumer perception. Precision penetrometers are used to measure the effect of different treatments, such as storage, drying, freezing, cooking, etc.
Expression of Helios in Peripherally Induced Foxp3+ Regulatory T Cells

The transcription factor Helios has been reported to be a marker of regulatory T cells (Treg) of thymic origin, distinguishing them from Treg induced in the periphery (iTreg). In this study, we demonstrate Helios expression in Foxp3+ iTreg, both in vitro and in vivo. Following i.v. peptide injection, in vivo Helios expression in adoptively transferred TCR transgenic T cells was more rapid than Foxp3 induction but less stable at later time points without a second injection of peptide. Our in vitro data suggest that APC influence Helios expression in a manner distinct from stimuli required for Foxp3 induction. Thus, Helios expression in iTreg may reflect the context of stimulation during Foxp3 induction. In summary, the robust Helios expression we observe in iTreg precludes its use as a marker of thymic Treg.
Securing Low-cost RFID Systems: A Research Survey

RFID (Radio Frequency IDentification) technology has moved from academic obscurity into mainstream business and practice. Although this technology has many catching and exclusive characteristics, security and privacy issues associated are not easy to address due to tags’ modest computational and storage capabilities and the necessity to keep their prices low. This paper provides a general overview of the rather broad area of RFID security and privacy and gives the main citations for the comprehensive understanding and further explorations of this area. To be specific, previous attempts to enable or increase the security and privacy of the low-cost RFID systems are examined, including: (1) design and cryptanalysis of lightweight ciphers; (2) privacy-preserving authentication protocols and their designing requirements; and (3) non-conventional solutions leveraging physical characteristics of RFID tags or physical layer of the tag-reader communication for security and privacy purposes.
Collaboratively developing instructional activities of conceptual change through the Internet: Science teachers' perspectives

L'Internet presente l'avantage d'offrir une quantite d'archives et de documentation importante. Les enseignants y trouvent desormais les informations necessaires a la preparation de leur cours et a leur enrichissement personnel. L'auteur explique ici la possibilite d'une collaboration entre enseignants dans le but de creer des activites pedagogiques et de rassembler leurs idees.
Spatial Navigation Impairment in Healthy Aging and Alzheimer’s Disease

The prevailing number of studies dealing with spatial navigation in animals and also in human have been connecting it to the function of the medial-temporal lobe (MTL), hypothesized to serve as the neuronal basis for the spatial cognitive map. Changes in the MTL are characteristic for both healthy aging and Alzheimer’s disease (AD), with markedly more severe changes in AD. The level of hippocampal dysfunction therefore counts among the boundaries between healthy aging and development of AD. Furthermore, the decline in the spatial navigation abilities has been described for healthy aging and is among the diagnostics marks of early AD. While the impact of this decline on the life of elderly seems to be minor, subjects suffering AD become lost in new environments and later in the course of the disease even inside their homes. The spatial navigation is however a complex process using a number of brain regions besides MTL. The regions discussed in this review also include prefrontal cortex (PFC), whose changes in healthy aging are often considered more typical than changes in MTL, and parietal cortex documented to deteriorate from the very early stages of AD. Due to its complexity, spatial navigation is a promising cognitive ability to be investigated in the phases of development from healthy aged to AD. The aim of this review is to investigate the complexity of the spatial navigation and its neural basis in healthy aging and in AD, including several available studies concerning the boundary between these two. We will focus on the differences in the spatial navigation abilities between healthy aging and AD and on the potential of spatial navigation to differentiate between them. The current review follows up two papers on similar topic (Iachini et al., 2009; Moffat, 2009) and in contrast to them focuses just on wayfinding and navigation, its underlying neural structures and the distinction between healthy aging and Alzheimer’s disease.
Structural and Functional Study of Apoptosis-linked Gene-2·Heme-binding Protein 2 Interactions in HIV-1 Production*

In the HIV-1 replication cycle, the endosomal sorting complex required for transport (ESCRT) machinery promotes viral budding and release in the late stages. In this process, the ESCRT proteins, ALIX and TSG101, are recruited through interactions with HIV-1 Gag p6. ALG-2, also known as PDCD6, interacts with both ALIX and TSG101 and bridges ESCRT-III and ESCRT-I. In this study, we show that ALG-2 affects HIV-1 production negatively at both the exogenous and endogenous levels. Through a yeast two-hybrid screen, we identified HEBP2 as the binding partner of ALG-2, and we solved the crystal structure of the ALG-2·HEBP2 complex. The function of ALG-2·HEBP2 complex in HIV-1 replication was further explored. ALG-2 inhibits HIV-1 production by affecting Gag expression and distribution, and HEBP2 might aid this process by tethering ALG-2 in the cytoplasm.
Fast estimators of time delay and Doppler stretch based on discrete-time methods

Estimation of the time delay and the Doppler stretch of a signal is required in several signal processing applications, This paper is focused on the joint fine estimation of these two parameters by a fast interpolation of the estimated ambiguity function. Four discrete-time methods (viz. multirate, piecewise scaling, linear scaling, and indirect estimators), based on an orthogonal model, are introduced. Their mean square error is mathematically derived for random signals corrupted by additive random noises. The obtained expressions have been evaluated for some typical parameter sets in the reference case of Gaussian signals and noises. The numerical results, compared with the accuracy of a continuous-time estimator, show the near efficiency of the multirate estimator for a wide range of SNRs. In fact, the adjustable multirate estimator can operate under near optimal conditions, unlike the approximate (i.e., piecewise and linear) scaling and the indirect methods based on constant sampling rates.
The Changing Role Of Urban Heritage: Governance And Stakeholders’ Perceptions In Turkey And The United Arab Emirates

Bu makalede, kultur mirasinin kent yasamindaki degisen rolu ile ilgili paydaslarin kultur mirasina karsi tutumlari arasindaki iliskinin ortaya konmasi amaclanmistir. Konu, yazarin 2008-11 yillarinda hazirladigi ‘Kentsel Koruma Projelerinde Aktorlerin Orgutlenmesi’ baslikli doktora tez calismasi kapsaminda Turkiye icinden secilmis bazi kentler, ve ayni zamanda yazarin 2008-12 yillarinda calistigi, Birlesik Arap Emirlikleri’nin Abu Dabi emirligindeki yerlesimler cercevesinde ele alinmistir. Bu karsilastirmali incelemenin amaci, bu iki farkli ulke arasinda gozlenebilecek benzer olgulari ve her bir ulkeye ozgu ozgul durumlari saptamak olmustur. Kuresellesen dunya ve mesleki aglar goz onunde bulunduruldugunda, bu tur karsilastirmalarin, planlama ve mimari koruma pratiginin cesitli baglamlari arasinda mumkun olabilecek capraz etkilenmelerin kapsamini anlamaya yardimci olacagi dusunulmektedir. Yukarida anilan arastirma ve uygulama deneyimlerinden ortaya cikan sonuc, kentlerin planlamasi, gelisimi ve kamusal yasaminda kultur mirasinin oynayabilecegi rolun, koruma surecinde yer alan paydaslarin tutumlariyla ve surecte oynadiklari rollerle yakindan iliskili oldugu yonundedir. Kultur mirasinin kent yasaminda aktif bir rol oynayabilmesi veya imar baskilari ile cagdas sosyal talepler karsisinda ozgunlugunu koruyabilmesi, her biri kendi farkli cikarlari ve kapasiteleri olan cesitli paydaslar arasindaki muzakerelerin sonucuna gore sekillenmektedir. Turkiye ve BAE’deki gelismeler gozlemlendiginde, iki ulkenin farkli tarihcelerine ve sosyo-politik yapilarina karsin, ikisinin de kultur mirasinin rolu ve paydaslar bakimindan dunyadaki gelismelerden etkilendikleri ve bunlara dahil olduklari soylenebilir. Iki ulke deneyiminin en onemli ortak paydasi, genel bir modernlesme surecidir, ancak surecin farkli asamalarinda durmakta ve farkli adimlardan gecerek ilerlemektedirler. Bu toplumlarin geleneksel ve muhafazakar kulturel yapilari goz onune alinarak, izlendigi iddia edilen ve uzun vadede yavas da olsa gerceklesen genel egilimin modernlesme ve demokratiklesme olmasina karsin, bu puruzsuz olmayan, hatta cetin ve sancili sayilacak surecte ilerlenirken donem donem, tamiri mumku olmayan kayiplara yol acan geri adimlar da atilabilmektedir. Her ulkede de, kultur mirasinin imar ve genel kentsel dinamikler karsisindaki rolunu desteklemek icin mucadele verilmesi gerektigi bir diger ortak noktadir. Ulkelerin ekonomik gucleri ne olursa olsun, kultur mirasini korumak, kaynaklari ayirma gucune sahip paydaslarin verdigi degere, gosterdigi ilgi ve siyasi iradeye baglidir ve bu gercek dunyanin her yerinde gecerli oldugunu gostermektedir. Anahtar kelimeler: Paydaslar, kentsel koruma, kuresellesme, Turkiye, Birlesik Arap Emirlikleri Keywords: Stakeholders, urban conservation, globalization, Turkey, United Arab Emirates
Temperature Measurements with Thermocouples Used in a Thermo-electric Hybrid Solar System

The aim of this work is to acquire temperature from as much sensors as possible. The sensors are PT 100 and PT 1000 type thermocouples placed strategically in key parts of a thermo-electric hybrid solar system. The solar system is made of a solar collector with parabola shape, covered with hexagonal-shaped reflective mirrors. The solar concentrator has a vacuum chamber and it is built around a TEG and has the possibility to produce heated water and electricity. The temperature acquisition is made with a 4-channel RTD input module which is connected to the computer via the RS-485 industrial serial port. To make temperature measurement on multiple points, more RTD input modules can be used via the same RS-485 channel, but with different address. The data is logged, both locally and online in an SQL database, with the usage of acquisition software.
SLE/myositis overlap: are the manifestations of SLE different in overlap disease?

Myositis is a rare but recognized complication of systemic lupus erythematosus (SLE). This study compares clinical and laboratory features in patients with SLE complicated by myositis with patients with SLE who do not have myositis. Thus we reviewed the notes of 10 patients with an overlap of biopsy-proven myositis and SLE and compared their clinical, serological and immunogenetic features with 290 patients with SLE without myositis. Our data suggests that patients with SLE associated with myositis are more likely to have alopecia, oral ulcers, erosive joint disease and pulmonary disease but less likely to have renal disease. Our SLE/myositis patients were likely to die at a younger age. The overall disease process seems to be influenced by the presence of antiRNP autoantibodies.
A synthetic fraction of feline facial pheromones calms but does not reduce struggling in cats before venous catheterization.

OBJECTIVE To evaluate whether a synthetic analogue of feline facial pheromone (FFP) calms cats before, and reduces struggling during intravenous catheterization. DESIGN Block-randomized, 'blinded' clinical trial. ANIMALS Seventy-seven healthy cats presented for elective surgery. PROCEDURE Cats given glycopyrrolate and oxymorphone were assigned to one of four treatments: acepromazine and exposure to FFP (aceFFP); acepromazine and exposure to a placebo (acePlac); exposure to FFP only (FFP) and exposure to placebo only (Plac). The behaviour of cats was recorded on videotape for evaluation by assessors unaware of treatment group. Cats' veins were then catheterized by veterinary students unaware of the study protocol. Based on each cat's response to catheterization, the student independently decided whether intramuscular ketamine was required. RESULTS Cats in the aceFFP group appeared to be calmer than acePlac cats on the basis of head position and their location in the cage (suggesting benefit from FFP among cats receiving acepromazine) but appeared to be less sedated. Cats in the aceFFP group also appeared to be calmer than FFP cats on the basis of head position and location in the cage. Feline facial pheromone cats were also calmer than Plac cats when compared using body and leg position. Exposure to FFP did not significantly reduce struggling at catheterization, nevertheless, the students were able to catheterize the veins in all cats. CONCLUSION AND CLINICAL RELEVANCE There were no detrimental behavioural effects associated with either FFP or acepromazine. The FFP had additional calming effects in cats given acepromazine and, to a lesser degree, helped to calm cats that were not given acepromazine. Feline facial pheromone helps to calm cats in unfamiliar surroundings.
Involvement of inhibin in the regulation of follicle-stimulating hormone secretion in the young adult male Shiba goat.

The roles of inhibin and testosterone in the regulation of gonadotropin secretion were investigated in young adult male Shiba goats (8-12 months of age). Plasma levels of inhibin but not testosterone abruptly decreased after hemicastration (75% of the initial level), concomitant with a progressive rise in plasma levels of FSH. Removal of the remaining testis at 33 days after the hemicastration quickly decreased plasma levels of both inhibin and testosterone and induced a progressive increase in plasma FSH and LH. Implantation of testosterone sheets immediately after castration suppressed the increase in plasma FSH in part only, whereas the increase in LH secretion was almost completely suppressed. An i.v. injection of antiserum against [Tyr30] porcine inhibin alpha(1-30) resulted in a significant increase in plasma FSH in a dose-dependent manner, without altering plasma concentrations of LH. These findings clearly indicate that both inhibin and testosterone physiologically regulate FSH secretion and that testosterone is the principal gonadal factor regulating LH secretion in the adult male goat.
Diagnostic accuracy of CERAD total score in a Colombian cohort with mild cognitive impairment and Alzheimer's disease affected by E280A mutation on presenilin-1 gene

ABSTRACT Background: This study aimed to determine Consortium to Establish a Registry for Alzheimer's Disease (CERAD) Neuropsychological Assessment Battery total score diagnostic accuracy in the diagnosis of mild cognitive impairment (MCI) and dementia in familial Alzheimer's disease (FAD) with E280A mutation on presenilin-1 gene (PSEN1). Methods: A cross-sectional study was conducted in a cohort of PSEN1 E280A carriers and non-carriers assessed between January 1995 and February 2013. During the first neuropsychological assessment, 76 were having dementia, 46 had MCI, and 1,576 were asymptomatic. CERAD cut-off points were established for MCI and dementia using a Receiver Operating Characteristics (ROC) analysis, and were further analyzed according to education level in two groups: low education level (eight years or less), and high education level (over eight years). Results: The area under curve–ROC CERAD total score for dementia was 0.994 (95% CI = 0.989–0.999), and that for MCI was 0.862 (95% CI = 0.816–0.908). The dementia diagnosis cut-off point for the low education group was 54, (98.4% sensitivity, 92.6% specificity), and that for the high education group was 67 (100% sensitivity, 94.1% specificity). The MCI diagnosis cut-off point for the low education group was 66 (91.2% sensitivity, 56.4% specificity), and that for the high education group was 72 (91.7% sensitivity, 76.3% specificity). Conclusions: The CERAD total score is a useful screening tool for dementia and MCI in a population at risk of FAD.
Clinical data mining and research in the allergy office

Purpose of reviewMore data are anticipated from the expected increase in use of electronic health records (EHRs). Upcoming initiatives require reporting of quality measures, meaningful use of clinical decision support, alert systems, and pharmacovigilance – knowledge resulting through use of EHRs. Data mining is a new tool that will help us manage information and derive knowledge from these data, and is a part of evolving new disciplines of informatics and knowledge management. Recent findingsStudies are reported from smaller clinic data marts to larger repositories and warehouses in various health systems, biomedical registries, and the medical literature on the Internet. Data mining technologies show promise and challenges. Outcome measures as structured data and narrative text can be mined with human assistance and newer automated natural language processing software. Despite advances, the growing diversity of clinic EHRs lack integration and interoperability with Internet-based biomedical databases. SummaryAllergists have the capability to mine clinic EHRs to discover new information, which may be hidden in charts. A central allergy computer can serve not just as a registry but also allows functionalities to enable EHRs' meaningful use. Harmonization of technological and organizational standards will allow seamless use of new natural language processing (NLP) tools and ontologies through a semantic web.
Racial differences in the association between gestational diabetes mellitus and risk of type 2 diabetes.

BACKGROUND It is recognized that a history of gestational diabetes mellitus (GDM) predicts incident type 2 diabetes in women. However, it is unclear if there is a racial disparity between the association of GDM and type 2 diabetes. METHODS We studied 1,142 women with a history of GDM and 18,856 women without a history of GDM aged 13-50 years with their first record of pregnancy in Louisiana State University Hospital-Based Longitudinal Study database between 1990 and 2009. History of GDM was used to predict incident type 2 diabetes. RESULTS During a mean follow-up of 8.6 years, 1,394 women developed type 2 diabetes. The multivariable adjusted hazard ratio (HR) of type 2 diabetes was 6.52 (95% confidence interval [CI] 5.73-7.43) among women with GDM compared to women without GDM. Stratification by age, race, and body mass index (BMI) gave similar results. Compared with African American and white women without a history of GDM, the relative risk for type 2 diabetes was higher in African American women than in white women with a history of GDM. Compared with non-GDM women compartments, GDM women after delivery for <1, 1.0-3.9, 4.0-5.9, 6.0-7.9, 8-9.9, and ≥10.0 years had 4.00, 5.44, 4.26, 3.16, 4.49, and 4.17 times higher risk of having type 2 diabetes, respectively. CONCLUSIONS A history of GDM is a strong predictor of subsequent type 2 diabetes among Louisiana women, especially among African American women.
PRE-CLINICAL EVALUATION OF EXTRACTS AND ESSENTIAL OILS FROM BETEL-LIKE SCENT PIPER SPECIES IDENTIFIED POTENTIAL CANCER TREATMENT

Background: Nine Piper species with betel-like scents are sources of industrial and medicinal aromatic chemicals, but there is lack of information on cytotoxicity and genotoxicity for human safety, including how these plants impact human cervical cancer cell line. Methods: Plant leaves were extracted with hexane and hydro-distilled for essential oils. The extracts and oils were pre-clinically studied based on cyto - and genotoxicity using microculture tetrazolium (MTT) and comet assays. Results: The crude extracts showed an IC50 in leukocytes and HeLa cells of 58.59-97.31 mg/ml and 34.91-101.79 mg/ml, the LD50 is higher than 5000 mg/kg. With lower values than the crude extracts, the essential oils showed an IC50 in leukocytes and HeLa cells of 0.023-0.059 μg/ml and 0.025-0.043 μg/ml the LD50 is less than 50 mg/kg. IC50 values showed that the essential oils were highly toxic than the crude extracts. At the level of human genetic materials, the crude extracts of two species, including P. betloides and P. crocatum, showed a significant toxicity (p < 0.05) in leukocytes. The other samples were non-toxic. The crude extracts of all samples showed significant genotoxicity in HeLa cells. The essential oils of all studied Piper species showed insignificant toxicity in leukocytes. For HeLa cells, the eight-studied species showed significant toxicity in HeLa cells, whereas only P. submultinerve showed insignificant toxicity. Conclusion: The crude extracts and essential oils should be tested as putative cervical cancer treatments due to less toxicity in human normal cells.