Miracle-dz/UniFAR-FTUs huggingface dataset:
A composite map of expressed sequences in maize.

A maize genetic map based mainly on expressed sequences has been constructed. The map incorporates data from four segregating populations. Three recombinant inbred line populations were derived from the nonreciprocal crosses between three inbred lines. A map derived from an independent F2 progeny from one of the crosses was also used. With a total of 521 genotyped individuals, accuracy in gene order is expected. Five sources of markers were used: (i) 109 loci corresponding to 69 genes of known function, (ii) 39 loci controlling protein position shifts revealed by two-dimensional electrophoresis, (iii) 8 isozyme loci, (iv) 17 loci corresponding to 14 sequenced cDNAs for which no homology was found in gene banks, and (v) 102 loci corresponding to 81 anonymous probes. As many loci were common to all maps, we tested heterogeneity between recombination fractions. The comparison of recombination fractions revealed: (i) a good correspondence between the maps derived from the same cross, (ii) few significant differences in interval distances, and (iii) global differences, which can reach 20% of the total map length. A composite map of 275 loci covering 1765 cM has been constructed. Key words : Zea mays L. , RFLP, genetic map, molecular markers, proteins.
Compact Quadruplet Bandpass Filter Based on Alternative J/K Inverters and $\lambda/4$  Resonators

This letter presents the proposal and synthesis design of a novel compact microstrip quadruplet bandpass filter (BPF) based on alternative J/K inverters and λ/4 resonators. The proposed quadruplet bandpass prototype is firstly derived from the conventional one with lumped LC resonators and the J-inverters. The mainline coupling is implemented by cascading four λ/4 resonators via the alternative J and K inverters, resulting in the achievement of the generalized Chebyshev in-band response. Meanwhile, the first and fourth resonators are cross-coupled via magnetic coupling so as to simultaneously produce transmission zeros below and above the desired passband. Finally, a microstrip quadruplet BPF at 2.5 GHz with a fractional bandwidth of 12.0% is designed, and the measured results of the fabricated filter show consistent match with its theoretical ones.
Motor neuron disease and adult hexosaminidase a deficiency in two families: Evidence for multisystem degeneration

We studied three patients from two unrelated families with adult hexosaminidase A deficiency. A 30‐year‐old, non‐Jewish proband in the first family had juvenile amyotrophic lateral sclerosis that evolved to mild demetia, ataxia, and axonal (neuronal) motor‐sensory peripheral neuropathy. A 36‐year‐old Jewish proband in the second family had “pure” spinal muscular atrophy. One supposedly healthy brother of the first proband was found to have borderline IQ, mild spasicity, ataxia but no evidence of motor neuron disease. Marked cerebellar atrophy was detected by head scans in all three patients. In both probands electromyograms were chacteriszed prominent, complex repetitive discharges in many muscles. Hexosaminidase A activities against the artificial substrate were similar to those reported in infantile Tay‐Sachs disease; however, the hexosaminidase A level against GM2 substrates was higher than that found infantile Tay‐Sachs disease. The hexosaminidase A levels of the parents were in the heterozygous range. Motor neuron disease in our patients and in those previously described appears to be park of a multisystem degeneration of the nervous system.
The effects of dietary levels of inorganic phosphorus, calcium and cholecalciferol on the digestibility of phytate-P by the chick

Male broiler chicks (1-d-old; Ross one) were given either a control diet containing recommended levels of phosphorus, calcium and cholecalciferol or experimental diets low in P and with variable levels of Ca (normal and low) and cholecalciferol (normal or high). The low-P diet with normal levels of Ca and cholecalciferol induced a hypophosphataemia and a hypercalcaemia which was reflected in reduced tibia length and weight and in reduced Ca, P and magnesium contents of tibia. The phytate digestibility remained normal while the retention of P and Ca fell significantly. The lowering of Ca alone elevated phytate digestibility and restored P and Ca retention. The hypercalcaemia and hypophosphataemia remained and tibia mineralization remained impaired. The raising of cholecalciferol alone dramatically increased phytate digestibility and the retention of Ca and P. While this remedied the hypercalcaemia, the hypophosphataemia persisted as did the diminution of tibia weight. The simultaneous lowering of dietary Ca and elevation of cholecalciferol on low-P diets restored all variables to the levels for the control diet. Circulating levels of 1,25-dihydroxycholecalciferol were significantly elevated by low-P diets, more so with high cholecalciferol intakes. However, Ca did not influence 1,25-dihydroxycholecalciferol levels in plasma
The implementation of a KNN classifier on FPGA with a parallel and pipelined architecture based on Predetermined Range Search

K-nearest neighbor (KNN) classification algorithm performs slowly for large scale training set and high dimensions. To overcome the disadvantage, we need to focus on the points within a predetermined range, without changing the precision. This method is named Predetermined Range Search (PRS). In this paper, we proposed a method to find the reference distance (ReDist), a parallel and pipelined architecture based on PRS to implement KNN classification algorithm on FPGA. Besides, we use real SPECT dataset for evaluation. The result shows that clock frequency is up to 186.4MHz on Virtex 4 which is 1.4× faster than the conventional design. Meanwhile, this novel architecture has a smaller BRAMs (Block RAMs) coverage and a simpler circuit structure.
Knowledge-AidedMultichannel Adaptive SAR / GMTI Processing : Algorithm and Experimental Results

The multichannel synthetic aperture radar ground moving target indication (SAR/GMTI) technique is a simplified implementation of space-time adaptive processing (STAP), which has been proved to be feasible in the past decades. However, its detection performance will be degraded in heterogeneous environments due to the rapidly varying clutter characteristics. Knowledge-aided (KA) STAP provides an effective way to deal with the nonstationary problem in real-world clutter environment. Based on the KA STAP methods, this paper proposes a KA algorithm for adaptive SAR/GMTI processing in heterogeneous environments. It reduces sample support by its fast convergence properties and shows robust to non-stationary clutter distribution relative to the traditional adaptive SAR/GMTI scheme. Experimental clutter suppression results are employed to verify the virtue of this algorithm.
Serological Relationships ofCryptococcus spp.: Distribution of Antigenic Factors inCryptococcus and Intraspecies Diversity

ABSTRACT The antigenic formulas of 34 species in the genusCryptococcus were determined by using type strains and eight factor sera prepared from adsorption experiments withCryptococcus neoformans serotypes. These antigenic factors were shared by 19 species. The strains used could be divided into eight serological groups. The patterns of groups 1, 2, 3, 5, and 6 were the same as the patterns of C. neoformans serotypes A, D, A-D, B, and C, respectively. The species belonging to group 4 reacted to factor sera 1, 2, and 3. Group 7 contained one species that reacted only to factor serum 1. The 15 species in group 8 did not react to any of the factor sera used. Compared to the reported molecular phylogenetic tree, the serological and phylogenetic data were correlated in the Filobasidium lineage. All the members of the albidus clade in the Filobasidium lineage had antigens 1, 2, and 3, and all the strains in the magnus clade belonged to serogroup 8. Moreover, intraspecies diversity was examined using strains of C. curvatus, C. humicolus, andC. laurentii. Serological heterogeneity was observed in the species C. humicolus and C. laurentii, as well as in phylogenetic relationships previously published. Using serological features, similarities and differences betweenCryptococcus species were demonstrated. Our study contributes to a better description of the genusCryptococcus and related species phenotypically and phylogenetically.
Droperidol Inhibits the Effects of Intravenous Ketamine on Central Hemodynamics and Myocardial Oxygen Consumption in Patients with Generalized Atherosclerotic Disease

A 2-mg/kg dose of ketamine was administered intravenously to 16 patients with generalized atherosclerotic disease. Eight patients were given 200 μ/kg of droperidol intravenously 10 min before ketamine administration; eight patients not given droperidol served as controls. Central hemodynamics, coronary flow (thermodilution technique) and myocardial oxygen, lactate, hypoxanthine, and catecholamine balances were studied. In control patients, ketamine increased mean blood pressure by 42%, pulmonary capillary wedge pressure by 144%, mean right atrial pressure by 60%, heart rate by 15%, and systemic vascular resistance by 40% without changes in cardiac index, stroke volume index, or left ventricular stroke work index. These data indicate that cardiac performance did not increase in parallel with the rise in afterload. However, the 50% increase in myocardial oxygen demand was associated with a 48% increase in coronary blood flow without changes in coronary vascular resistance or myocardial oxygen extraction. Augmented sympathetic activity was manifested by 397% and 164% increases in plasma levels of epinephrine and norepinephrine, respectively. The hemodynamic and cardiometabolic effects of ketamine were abolished when patients were pretreated with droperidol. The increase in plasma epinephrine levels was likewise inhibited by droperidol; significantly lower plasma norepinephrine levels also were observed. These findings suggest that droperidol inhibits the cardiovascular effects of ketamine by a centrally mediated reduction in sympathetic activity and by peripheral alpha receptor blockade.
Characterization of a Novel DWD Protein that Participates in Heat Stress Response in Arabidopsis

Cullin4-RING ubiquitin ligase (CRL4) is a family of multi-subunit E3 ligases. To investigate the possible involvement of CRL4 in heat stress response, we screened T-DNA insertion mutants of putative CRL4 substrate receptors that exhibited altered patterns in response to heat stress. One of the mutants exhibited heat stress tolerance and was named heat stress tolerant DWD1 (htd1). Introduction of HTD1 gene into htd1-1 led to recovery of heat sensitivity to the wild type level, confirming that the decrease of HTD1 transcripts resulted in heat tolerance. Therefore, HTD1 plays a negative role in thermotolerance in Arabidopsis. Additionally, HTD1 directly interacted with DDB1a in yeast two-hybrid assays and associated with DDB1b in vivo, supporting that it could be a part of a CRL4 complex. Various heat-inducible genes such as HSP14.7, HSP21, At2g03020 and WRKY28 were hyper-induced in htd1-1, indicating that HTD1 could function as a negative regulator for the expression of such genes and that these genes might contribute to thermotolerance of htd1-1, at least in part. HTD1 was associated with HSP90-1, a crucial regulator of thermotolerance, in vivo, even though the decrease of HTD1 did not affect the accumulation pattern of HSP90-1 in Arabidopsis. These findings indicate that a negative role of HTD1 in thermotolerance might be achieved through its association with HSP90-1, possibly by disturbing the action of HSP90-1, not by the degradation of HSP90-1. This study will serve as an important step toward understanding of the functional connection between CRL4-mediated processes and plant heat stress signaling.
Estrogen activates protein kinase C in neurons: role in neuroprotection

It has been previously demonstrated that estrogen can protect neurons from a variety of insults, including β‐amyloid (Aβ). Recent studies have shown that estrogen can rapidly modulate intracellular signaling pathways involved in cell survival. In particular, estrogen activates protein kinase C (PKC) in a variety of cell types. This enzyme plays a key role in many cellular events, including regulation of apoptosis. In this study, we show that 17β‐estradiol (E2) rapidly increases PKC activity in primary cultures of rat cerebrocortical neurons. A 1 h pre‐treatment with E2 or phorbol‐12‐myristate‐13‐acetate (PMA), a potent activator of PKC, protects neurons against Aβ toxicity. Protection afforded by both PMA and E2 is blocked by pharmacological inhibitors of PKC. Further, depletion of PKC levels resulting from prolonged PMA exposure prevents subsequent E2 or PMA protection. Our results indicate that E2 activates PKC in neurons, and that PKC activation is an important step in estrogen protection against Aβ. These data provide new understanding into the mechanism(s) underlying estrogen neuroprotection, an action with therapeutic relevance to Alzheimer's disease and other age‐related neurodegenerative disorders.
DNA polymerase κ deficiency does not affect somatic hypermutation in mice

Somatic hypermutation (SH) in B cells undergoing T cell‐dependent immune responses generates high‐affinity antibodies that provide protective immunity. Most current models of SH postulate the introduction of a nick into the DNA and subsequent replication‐independent, error‐prone short‐patch synthesis by one or more DNA polymerases. The PolK (DinB1) gene encodes a specialized mammalian DNA polymerase called DNA polymerase κ (polκ), a member of the recently discovered Y family of DNA polymerases. The mouse PolK gene is expressed at high levels in the seminiferous tubules of the testis and in the adrenal cortex, and at lower levels in most other cells of the body including B lymphocytes. In vitro studies showed that polκ can act as an error‐prone polymerase, although they failed to ascribe a clear function to this enzyme. The ability of polκ to generate mutations when extending primers on undamaged DNA templates identifies this enzyme as a potential candidate for the introduction of nucleotide changes in the immunoglobulin (Ig) genes during the process of SH. Here we show that polκ‐deficient mice are viable, fertile and able to mount a normal immune response to the antigen (4‐hydroxy‐3‐nitrophenyl)acetyl‐chicken γ‐globulin (NP‐GC). They also mutate their Ig genes normally. However, polκ‐deficientembryonic fibroblasts are abnormally sensitive to killing following exposure to ultraviolet (UV) radiation, suggesting a role of polκ in translesion DNA synthesis.
Surgical Repair of Aortic Regurgitation With Left Ventricular Aneurysm Diagnosed Preoperatively as Aortico-Left Ventricular Tunnel

Aortico-left ventricular tunnel (ALVT) is a rare congenital anomaly presenting abnormal connection between the ascending aorta and the left ventricle. In most reported cases, the aortic end of the tunnel is above the right coronary sinus. Cases of ALVT related to the left aortic sinus are extremely rare. We herein report a case diagnosed preoperatively as ALVT arising from the left aortic sinus. The actual diagnosis observed at surgery was aortic valve insufficiency with a left ventricular outflow tract aneurysm. We successfully performed aortic valve repair and plication of the left ventricular aneurysm.
Diagnosis and management of postpartum haemorrhage

#### What you need to know Postpartum haemorrhage is a major cause of death during pregnancy and early motherhood, accounting for 25% of maternal deaths worldwide,1 and is the second leading direct cause of maternal deaths in the UK.2 It is defined as blood loss of more than 500 mL from the female genital tract after delivery of the fetus (or >1000 mL after a caesarean section). Primary postpartum haemorrhage occurs within the first 24 hours of delivery, whereas secondary postpartum haemorrhage occurs between 24 hours and 12 weeks after delivery and is less common.1 For every maternal death due to postpartum haemorrhage, there are at least 10 “near-misses. ” Serious maternal morbidities include multiorgan failure, multiple blood transfusion, and peripartum hysterectomy.1 There have been recent advances in the management of postpartum haemorrhage secondary to coagulopathy and abnormal invasion of the placenta.3 This review highlights the causes, diagnosis, and management of postpartum haemorrhage and is aimed at those involved in obstetric and postnatal care. #### Sources and selection criteria We searched PubMed using the key words “postpartum haemorrhage,” “balloon tamponade,” “uterine compression suture,” “embolization,” and “obstetric haemorrhage” from 1981 to 2016. We also considered review articles from 2001 to 2016 …
Geometrically robust image content authentication using Zernike moments

A geometrically robust image content authentication algorithm using modified Zernike moments is proposed in this paper. Firstly the characteristic of image Zernike moments magnitude is quantified and coded, and then embedded in the original image as watermark. When verifying the image, the variance of Zernike moments magnitude and watermark of test image is computed to reconstruct the difference image with the complex angle of test image ZMS. The difference image indicates whether test image has been tampered and the tamper location. This algorithm is robust to geometry distortion of rotation, scale and translation. It can resist the processes such as compression, enhance, filter and noise, and locate the tamper position correctly.
Two restriction endonucleases in Selenomonas ruminantium subsp. lactilytica

Crude protein extract from a recently isolated ruminal bacterium identified as Selenomonas ruminantium subsp. lactilytica specifically cleaved DNA. This ability was due to the presence of two site‐specific restriction endonucleases. SrlI, a NaeI schizomer, recognizes the 5′‐GCCGGC‐3′ sequence. SrlII, a NsiI schizomer, recognizes 5′‐ATGCAT‐3′.
The language of infectious disease: a light-hearted review.

Contemporary terminology related to infectious disease (ID) is a patchwork collection that includes foreign words, slang, euphemisms, misnomers, acronyms, and a variety of other terms referring to people, places, foods, colors, and animals. The only constant of any language is change, and, from early concepts of contagion to modern day “ID speak,” the language of the field has evolved in response to new developments in the identification, classification, epidemiology, diagnosis, and treatment of infectious agents and the associated diseases. This seriously light-hearted review of the ID language is in large part a personal perspective and commentary. Resources used include several dictionaries [1‐3], the International Classification of Diseases, Ninth Revision (ICD-9), various other references as noted, and the author’s experience and imagination. This review is written for the general ID community, but it may also be of interest to medical students, international medical graduates, ivy-covered professors in ivory towers, and aspiring authors of the “hot zone” type of infection-related fiction.
Trunk Muscle Activation in Open Stance and Square Stance Tennis Forehands

Electromyography of the trunk muscles were compared between the open and square stance forehand drives of 14 collegiate tennis players. Surface EMG were bilaterally collected from the rectus abdominis (RA), external oblique (EO), and erector spinae (ES) in open and square stance forehand drives. EMG data were transferred by telemetry, 12 bit A/D converted at 1000 Hz, and stored for analysis. Rectified and smoothed EMG data were normalized (NEMG) to maximal isometric voluntary contractions and mean NEMG were calculated during the forward swing and follow through phases of the stroke. A 2 x 2 x 2 x 6 factorial ANOVA (Gender, Stance, Phase, Muscle) with repeated measures on Subject showed significant (p < 0.05) effects of Gender, Muscle, Phase, and several interactions. The nonsignificant differences in muscle activation between stances did not support the belief of tennis experts that open stance forehands require greater trunk activation than square stance forehands. Mean NEMG of the ES were significantly (p < 0.05) larger than EO or RA, which was consistent with observations of tennis-specific strength imbalances and increasing incidence of low back injuries in tennis.
Use of Random Amplified Polymorphic DNA Analysis for Economically Important Food Crops

The objective of this review is to summarize numerous studies on the use of the random amplified polymorphic DNA (RAPD) technique on rice, corn, wheat, sorghum, barley, rye, and oats to examine its feasibility and validity for assessment of genetic variation, population genetics, mapping, linkage and marker assisted selection, phylogenetic analysis, and the detection of somaclonal variation. Also we discuss the advantages and limitations of RAPD. Molecular markers have entered the scene of genetic improvement in different fields of agricultural research. The simplicity of the RAPD technique made it ideal for genetic mapping, plant and animal breeding programs, and DNA fingerprinting, with particular utility in the field of population genetics.
Content-Based Cartoon Images Retrieval

Cartoon images play essential roles in our everyday lives especially in entertainment, education, and advertisement, that become an increasingly intensive research in the field of multimedia and computer graphics[1-2]. Cartoon image retrieval is bedrock of producer's new cartoon videos, particularly when provides initial planning to be elevated in so as to identify their intention of artistic [3]. Today, a number of researchers have exploited the concepts related to content based images retrieval (CBIR) to search for cartoon images containing particular object(s) of interest [4] This paper aims to design content-based retrieval system for cartoon images. The proposed image retrieval system consists of four basic stages “(image quantization, object extraction, feature extraction and similarity matching). Given a query image, the system extracts features for the query image which is a percentage of each index value (dominant color), cluster values for three bands of quantization image (RGB), and the weight of each index values (weight of each dominant color) depends on its location in the image, then compares it with the images features in database system in similarity matching stage and then the top 10 images are retrieved as the query results.