Miracle-dz/UniFAR-FTUs huggingface dataset:
Object-Specific Four-Path Network for Stroke Risk Stratification of Carotid Arteries in Ultrasound Images

Atherosclerotic carotid plaques have been shown to be closely associated with the risk of stroke. Since patients with symptomatic carotid plaques have a greater risk for stroke, stroke risk stratification based on the classification of carotid plaques into symptomatic or asymptomatic types is crucial in diagnosis, treatment planning, and medical treatment monitoring. A deep learning technique would be a good choice for implementing classification. Usually, to acquire a high-accuracy classification, a specific network architecture needs to be designed for a given classification task. In this study, we propose an object-specific four-path network (OSFP-Net) for stroke risk assessment by integrating ultrasound carotid plaques in both transverse and longitudinal sections of the bilateral carotid arteries. Each path of the OSFP-Net comprises of a feature extraction subnetwork (FE) and a feature downsampling subnetwork (FD). The FEs in the four paths use the same network structure to automatically extract features from ultrasound images of carotid plaques. The FDs use different object-specific pooling strategies for feature downsampling based on the observation that the sizes and shapes in the feature maps obtained from FEs should be different. The object-specific pooling strategies enable the network to accept arbitrarily sized carotid plaques as input and to capture a more informative context for improving the classification accuracy. Extensive experimental studies on a clinical dataset consisting of 333 subjects with 1332 carotid plaques show the superiority of our OSFP-Net against several state-of-the-art deep learning-based methods. The experimental results demonstrate better clinical agreement between the ground truth and the prediction, which indicates its great potential for use as a risk stratification and as a monitoring tool in the management of patients at risk for stroke.
A New Decision-Making Approach for Riyadh makes up 50 percent of the non-oil economy of Saudi Arabia

Saudi Arabia's capital, Riyadh, has grown from a small city of half-million people to a city of more than seven million people in the past fifty years. As the capital city of Saudi Arabia, Riyadh contributes significantly to the non-oil economy in the country. As a result, this study focused on reviewing the existing literature to assess the city's role in the nation's non-oil economy in the last fifty years. The included studies had to be cross-sectional studies, reports, government publications, and ecological studies that reported Riyadh's role in Saudi Arabia's non-oil economy for the past five decades. One hundred twenty-three studies were initially screened to identify relevant sources. Further analysis and exclusion identified fifty relevant sources that were systematically reviewed. The quality of methodological designs was assessed in all the sources reviewed. The results indicate that Riyadh has been the focal city in diversifying the nation's economy. The review depicts that the general proportion of service industries comprised the major developments in the city. Most of the studies pointed out that Saudi Arabian government has pushed hard to make the country and hub for a non-oil and diversified economy. The study's results depict that the government requires a business to have offices in Riyadh even if they may be based in other cities. This move was adopted after the country suffered major economic setbacks every time there was an uncertain and certain fall in oil demand. The city has the largest service industry, manufacturing, construction, and finance in Saudi Arabia.
Suppression by Filarial Parasites Not IL-10, in the Induction of Proliferative Requirement for In Vivo Production of IL-4, But

Loss of T lymphocyte proliferation and the emergence of a host response that is dominated by a Th2-type proﬁle are well-established features of human ﬁlariasis. We have previously reported that adherent peritoneal exudate cells (PEC) from mice transplanted with adult Brugia malayi parasites suppress the proliferation of lymphocytes without blocking Ag-cytokine production in vitro. We now show that infection of mice with the infective larval (L3) stage of B. malayi generates a similar population of PEC. Suppressive cells are generated within 7 days of infection and mediate their effects through a nitric oxide-independent pathway. Both L3 and adult infection elicit high levels of host IL-4 whereas the microﬁlarial stage of the parasite induces IFN- g production and does not generate a similar form of suppression. Production of host IL-4 was necessary to allow the generation of suppressive PEC, given that IL-4-deﬁcient mice implanted with adult parasites failed to induce proliferative block. However, IL-10-deﬁcient mice implanted with adult parasites resulted in T cell suppression, indicating that IL-10 is not essential for the induction of hyporesponsiveness. Neither IL-4 nor IL-10 were directly responsible for ablating cellular proliferation in vitro, as the addition of neutralizing Ab to either cytokine did not reverse the proliferative block. Thus, IL-4 produced in vivo in response to ﬁlarial L3 and adult parasites is essential for the induction of proliferative suppression but is not itself the suppressive factor. The Journal of Immunology, 1998, 160: 1304–1312. Unterschleissheim, Germany). The proportion of macrophages, lympho- cytes, mast cells, and eosinophils was determined by morphologic exam-ination of at least 300 cells in randomly selected ﬁelds using an Olympus BH2 microscope with a 3 100 objective. Infective stage larvae and adult parasites induce similar proﬁles of T cell suppression infected
Splitting Energy of Transmit Power Serving Grouping Users in Full-Duplex Networks under Imperfect Hardware

In this paper, we consider a wireless system providing power allocation fairness for grouping users by conducting a non-orthogonal multiple access (NOMA). In particular, a rigorous analysis is performed to evaluate performance of destination in a downlink of wireless system. With advances of NOMA, the user grouping scheme allows users to be shared the same frequency/power domain, and hence, fairness is guaranteed. In this regard, we focus on evaluation of the performance of a cell-center user and a cell-edge user in dedicated group. To enable forwarding function at cell-center user, we require the assistance of a full-duplex– (FD–) based relay to serve the cell-edge user. These users are assigned a fixed power allocation scheme. To characterize system performance, the closed-form expressions of the outage probability are computed for two users. To generalize channels in such system, Nakagami-m fading channels could be adopted to achieve complete theoretical analysis. Furthermore, we provide some comparisons of such FD NOMA under the impact of hardware impairment. We find that a significant improvement of outage probability can be achieved when the signal-to-noise ratio (SNR) at the source is high. Numerical results illustrate that both the analytical outage probability of the central user and the cell-edge user match the simulation results.
Pentraxin Superfamilies Immune Proteins of the Collectin and Resistant to the Antiviral Activities of Innate Pandemic H1N1 Influenza A Viruses Are

Acquired immune responses elicited to recent strains of seasonal H1N1 inﬂuenza viruses provide limited protection against emerg-ing A(H1N1) pandemic viruses. Accordingly, pre-existing or rapidly induced innate immune defenses are of critical importance in limiting early infection. Respiratory secretions contain proteins of the innate immune system, including members of the collectin and pentraxin superfamilies. These mediate potent antiviral activity and act as an initial barrier to inﬂuenza infection. In this study, we have examined the sensitivity of H1N1 viruses, including pandemic virus strains, for their sensitivity to collectins (surfactant protein [SP]-D and mannose-binding lectin [MBL]) and to the pentraxin PTX3. Human SP-D and MBL inhibited virus-induced hemagglutinating activity, blocked the enzymatic activity of the viral neuraminidase, and neutralized the ability of H1N1 viruses to infect human respiratory epithelial cells in a manner that correlated with the degree of glycosylation in the globular head of the hemagglutinin. Recent seasonal H1N1 viruses expressed three to four N -glycosylation sequons on the head of hemagglutinin and were very sensitive to inhibition by SP-D or MBL, whereas A(H1N1) pandemic viruses expressed a single N -glycosylation sequon and were resistant to either collectin. Of interest, both seasonal and pandemic H1N1 viruses were resistant to PTX3. Thus, unlike recent seasonal H1N1 strains of inﬂuenza virus, A(H1N1) pandemic viruses are resistant to the antiviral activities of innate immune proteins
Big Data Usage Intentionusing Toe Framework: Sri Lankan Context

Big data is huge amount of information that cannot be handled with conventional method.In various fields, the field of big data has an essential role to play.This research investigated that the Big Data Usage Intention of listed companies in Sri Lanka, is to provide empirical evidence concerning the Big Data Usage Intention of listed companies. Data were collected using survey and market research techniques in listed companies in CSE. For this purpose, descriptive, correlation, and multiple regression analysis was employed. In many fields of business and management, Big Data Analysis (BDA) is an emerging technology. Factors affecting the organizational intention to use this technology do not focus on extensive research. In order to fully exploit its advantages and therefore to study it, organizations should take it in a full and profound level. This research, based on the TOE, proposes and examines the determinants which influence the adoption of the BDA in the context of companies from Sri Lanka. There is large collection of data from 96 organizations, which helps us to understand the influences on the use of big data
A Novel Demultiplexing Design for Coarse WDM: Exploiting Material Dispersion

Abstract In this paper, a compact low-cost simple-to-fabricate demultiplexer is proposed for coarse wavelength division multiplexing (CWDM). The device consists of two layers of the same semiconductor material: the first layer is homogeneous medium with a given refractive index n2${n_2}$, while the second layer is an inhomogeneous medium, where its refractive index is graded according to a creation profile. The proposed design exploits the ray’s spatial shift that results from material dispersion as difference wavelengths propagate through the structure. Through analytical analysis and numerical evaluation, we investigate the effects of the various design parameters on the amount of achieved spatial shift between the adjacent wavelengths and the size of the device. The results show promising results for four- and eight-channel devices operating on the standard CWDM wavelength grid.
“ The Right to Live in the City ”: Exploring Discrimination Against the Urban Poor Inhabitants of Ubon Ratchathani, North - Eastern Thailand

: The purpose of this paper is to explore the concept of achieving the “ right to live in the city ” for poor urban inhabitants in north - eastern Thailand . We raise the question of who has the right to set the rules of urban spaces, which have changed significantly in terms of the spatial exclusion of poor people . Our study adopts a qualitative case study, using a purposive sampling technique . Interviews were conducted with 30 key informants between August and October 2018 . Data were coded, analysed and interpreted . Our findings show that the poor not only have restricted rights to physical space, but the inhabitants are prevented from having the right to live on their own land . We examine the context of new forms of “ right to live in the city ” associated with the right to historical identity, the right to equal distribution of resources, the right to equal access to resources, and the right to housing inheritance .
Cellsand Inhibit the Function of Infiltrating T Human Metastatic Melanoma Lymph Nodes Regulatory T Cells Are Overrepresented in high CD25+ Foxp3 Expressing CD4

Dominant tolerance is mediated by regulatory T cells (T reg ) that control harmful autoimmune T cells in the periphery. In this study, we investigate the implication of T reg in modulating inﬁltrating T lymphocytes in human metastatic melanoma. We found that CD4 (cid:1) CD25 high T cells are overrepresented in metastatic lymph nodes (LNs) with a 2-fold increased frequency compared with both tumor-free LNs and autologous PBMCs. These cells express the Foxp3 transcription factor, display an activated phenotype, and display a polyclonal TCR V (cid:2) chain repertoire. They inhibit in vitro the proliferation and cytokine production of inﬁltrating CD4 (cid:1) CD25 (cid:3) and CD8 (cid:1) T cells (IL-2, IFN- (cid:4) ) through a cell-contact-dependent mechanism, thus behaving as T reg . In some cases, the presence of T reg type 1/Th3-like lymphocytes could also be demonstrated. Thus, T reg are a major component of the immunosuppressive microenvironment of metastatic melanoma LNs. This could explain the poor clinical response of cancer patients under immunotherapeutic protocols, and provides a new basis for future immunotherapeutic strategies counteracting in vivo T reg to reinforce local antitumor immune responses. The Journal of Immunology, 2004, 173: 1444–1453.
Engineering Student Identities And The Navigation Of The Undergraduate Curriculum

Recent educational theory emphasizes the importance of considering identity processes in studying learning and development. In engineering education, identity has been cited as central in student development, for example, as a key factor in retention of students in the discipline. This paper examines how identity relates to students’ decisions about whether to remain in or switch out of engineering majors. We develop case studies of two students, both women and both members of underrepresented minority groups. One successfully gained admittance into her desired major, and one is considering leaving engineering. We argue that while each woman takes a different position on what engineering education should offer, both display a common, and we argue troubling, view of this educational experience. Our analysis seeks to explicate our ethnographic methods and to explore the broader possible significance for engineering education of the views that these women hold.
Tissue-specific transcription footprinting using ​ R ​ N ​ A ​ ​ P ​ oI

for the widely used model system ​ C. elegans ​ . Here, we introduce a method based on the ​ in vivo ​ covalent modification of DNA by transcribing RNA polymerases to determine genome-wide transcription patterns in single tissues of embryos or young adult animals. We show that the method is able to identify actively transcribed genes in tissues representing down to 0.2% of the somatic cells in adult animals. Additionally, this method can be Abstract Differential gene expression across cell types underlies the development and cell physiology in multicellular organisms. ​ C. elegans is a powerful, extensively used model to address these biological questions. A remaining bottleneck relates, however, to the difficulty to obtain comprehensive tissue-specific gene transcription data, since available methods are still challenging to execute and/or require large worm populations. Here, we introduce the ​ R ​ N ​ A P ​ ol Dam ​ ID (RAPID) approach, in which the Dam methyltransferase is fused to a ubiquitous RNA polymerase subunit in order to create transcriptional footprints ​ via ​ methyl marks on the DNA of transcribed genes. To validate the method, we determined the polymerase footprints in whole animals, sorted embryonic blastomeres and in different tissues from intact young adults by driving Dam fusion expression tissue-specifically. We obtained meaningful transcriptional footprints in line with RNA-seq studies in whole animals or specific tissues. To challenge the sensitivity of RAPID and demonstrate its utility to determine novel tissue-specific transcriptional profiles, we determined the transcriptional footprints of the pair of XXX neuroendocrine cells, representing 0.2% of the somatic cell content of the animals. We identified 2362 candidate genes with putatively active transcription in XXX cells, among which the few known markers for these cells. Using transcriptional reporters for a subset of new hits, we confirmed that the majority of them were expressed in XXX and identified novel XXX-specific markers. Taken together, our work establishes RAPID as a valid method for the determination of polymerase footprints in specific tissues of ​ C. elegans a fusion between a small subunit present in all three RNA polymerases, we show that the technique can be used on both fluorescently sorted blastomere cells, or DNA isolated from entire young adults using cell-type-specific expression generated by Cre/ ​ lox ​ . To test the versatility of the method, we determined the polymerase footprints in three different tissues at each stage. In young adults, these tissues represent between 10 and 0.2% of the somatic cells of the animal. We show that meaningful transcriptional patterns can be recovered using this technique, in line with previously used, RNA tagging/pulling and dissociation-based methods. We further explore how this technique can be used to discover tissue-specific markers and report here the identification of eight new reporters for adult
Enhanced Subsea Acoustically Aided Inertial Navigation

This paper treats the IMU calibration and validation problem in three settings: Factory production line with the aid of a precision multi-axis turntable, in-the-field on land and at sea, both without specialist test equipment. The treatment is limited to the IMU calibration parameters of key relevance for gyro-compassing grade optical gyroscopes and force-rebalanced pendulous accelerometers: Scale factor, bias and sensor axes misalignments. Focus is on lowdynamic marine applications e.g., subsea construction and survey. Two different methods of calibration are investigated: Kalman smoothing using an Aided Inertial Navigation System (AINS) framework, augmenting the error state Kalman filter (ESKF) to include the full set of IMU calibration parameters and a least squares approach, where the calibration parameters are determined by minimizing the magnitude of the INS error differential equation output. A method of evaluating calibrations is introduced and discussed. The two calibration methods are evaluated for factory use and results compared to a legacy proprietary method as well as in-field calibration/verification on land and at sea. The calibration methods shows similar navigation performance as the proprietary method. This validates both methods for factory calibration. Furthermore it is shown that the AINS method can calibrate in-field on land and at sea without the use of a precision multi-axis turntable. 1Department of Applied Mathemantics and Computer Science, Technical University of Denmark, DK-2800 Kgs. Lyngby, Denmark 2Sonardyne International Ltd., Yateley, United Kingdom
The empirical mode decomposition for removing displacement drift in structural earthquake responses

Will come into being "displacement drift",when the "large-mass method" is adopted to analyze the structural earthquake responses.A new algorithm to remove this drift components based on empirical mode decomposition(EMD) is put forward,which regards the drift component as the residue of EMD,separates and removes the residue from original signal of time history response data by using EMD,reconstructs the response signal though using intrinsic mode functions(IMF) of EMD.Then the displacement response signal approximated to real one is obtained.By applying the method to analyse earthquake time history responses of real bridge structures,the difficult problem of removing displacement drift from time histry data is successfully solved.The results of trial and true calculations are precise,so it can be used for the structural earthquake response analysis.
The Actuality and Strategy of Sports Fitness and Entertainment Industry during the Comfortable Society in Xi’an

Through document, social investigation, expert visitation, statistics, logical, organization, comparative analysis and so on, the research, with the great opportunity of powerful development of sports fitness and entertainment market Xi’an, analysis the actual of sports fitness and entertainment market both at home and abroad, is made on the actual of sports fitness and entertainment market in Xi’an and problems existed and how to resolve.
Automated Path Planning for unmanned aerial vehicle in Urban Dynamic Area

This paper addresses the path planning and autonomous obstacle avoidance problem of UAVs in urban dynamic area. A flight path planning strategy for UAVs in complex urban environments is proposed.First, the A* algorithm is used to construct a desired global path in a 3D static environment, which is used as the static reference path for dynamic obstacle avoidance below.The environmental and the key points of algorithm are also elaborated. In this paper, the dynamic obstacles are divided into three categories, then, in order to avoid the collision between dynamic obstacles and static optimal paths, two strategies to achieve local online path adjustment are proposed. Finally, the seven order minimum snap trajectories generation based on piecewise polynomials is utilized to smooth the flight path.We can obtain a smooth trajectory based on UAV dynamics and safety. The simulation results verify the effectiveness of the proposed UAV path planning strategy in the dynamic and complex urban area.
WHEN SEX MATTERS: A COMPARATIVE GENERALISED STRUCTURAL EQUATION MODEL (GSEM) FOR THE DETERMINANTS OF STUNTING AMONGST UNDER-FIVES IN UGANDA

The main aim of this study was to establish the differences in both the determinants of stunting and the causal mechanism through which the identified determinants influence stunting amongst male and female under-fives in Uganda. Literature shows that male children below the age of five years are at a higher risk of being stunted than their female counterparts. Specifically, studies in Uganda indicate that being a male child is positively associated with stunting while being a female is negatively associated with stunting. Data for 904 male and 829 female under-fives was extracted form UDHS-2016 survey dataset. Key variables for this study were identified and used in generating relevant models and paths. Structural equation modeling techniques was used in its generalized form (GSEM). The generalized nature necessitated specifying both the family and link functions for each response variables in the system of the model. Sex of the child (b4) was used as a grouping factor and the height for age (HAZ) scores were used to construct the status for stunting of under-fives. The estimated models and path clearly indicated that the set of underlying factors that influence male and female under-fives respectively were different and the path through which they influence stunting were different. However, some of the determinants that influenced stunting amongst male under-fives also influenced stunting amongst the female under-fives. To reduce the stunting problem to the desirable state, it is important to consider the multifaceted and complex nature of the risk factors that influence stunting amongst the under-fives but more importantly consider the different sex specific factors and their causal mechanism or paths through which they influence stunting.