Miracle-dz/UniFAR-FTUs huggingface dataset:
Effect of high intensity board training on upper body anaerobic capacity and short-lasting exercise performance.

Seven conditioned post-pubescent male subjects (VO2peak = 2.8 +/- 0.1 l.min-1) performed three high intensity board training sessions per week for an eight week period, followed by ten days of reduced training (taper). Subjects performed a 60 second all-out test, on a Biokinetic swim bench ergometer, on five occasions throughout the duration of the study. Testing occurred pre-training (T1), during the third week of training (T2), during the sixth week of training (T3), following eight weeks of training (T4), and post-taper (T5). Performance parameters as well as oxygen deficit (OD) were recorded during the 60 second all-out tests for the assessment of anaerobic capacity. Time trials were completed at times corresponding to T1, T3 and T5 over distances of 75, 140 and 250 metres. Over the duration of the study improvements of 17 percent (p < 0.05) and 60 percent (p < 0.01) were observed for Biokinetic swim bench mean power and peak power, respectively. Improvements in mean power and OD reached significance after five weeks of training. Improvements of 11 (p < 0.05), seven (p < 0.05) and six (p < 0.05) percent were noted from pre-training to post-taper for the 75, 140 and 250 metre time trials, respectively. Peak oxygen uptake improved by five percent from pre-training to post-taper which was almost significant at the 0.05 level (p = 0.052). Mean power correlated significantly with the 75 (r = -0.74, p < 0.05) and 140 (r = -0.79, p < 0.05) metre time trials, indicating that in-water performance and Biokinetic swim bench ergometry are well related. The ten day period of reduced training had no effect on performance parameters assessed during the 60 second all-out tests. It was concluded that improvements in the anaerobic energy systems, and associated performance in short-lasting exercise of high intensity, can be induced within five weeks of high intensity training with no decrements in the aerobic energy system.
[Physiologic nutrition studies in swine with ileorectal anastomoses. 2. The effect of nourseothricin on nutrient digestibility, amino acid absorption, protein utilization and mineral balance of a rye diet].

The supplement of nourseothricin (NT) to a rye diet did not have an influence on the precaecal and total apparent digestibility of the crude nutrients or the total digestibility of the amino acids (AA). NT produced significantly higher absorption of some AA in pigs with ileo-rectal anastomoses (IRA) which were orally supplied with electrolyte solution (ES). In general, IRA pigs showed the same results with regard to precaecal apparent AA absorption influenced by the AA pattern of endogenous protein as pigs with ileal cannulae. Functions in the large intestine seem to be important for the effect of NT supplements, as NT supplements to the diet of intact animals tendentially had a positive effect on N, Ca and P balances, IRA animals, however, showed a contrary effect. In comparison with the intracaecal infusion of ES, the oral supply of the IRA pigs resulted in higher N, Ca and P balances. The level of N utilization (N balance in % of the digested N) of the IRA pigs supplied orally was equally high as that of the intact animals (both groups without NT). As derives from literature and the available N, Ca and P balances--significantly influenced by ES supplements--an additional supplement of rations poor in crude fibres of 1 g Na/animal and day seems sufficient for covering the requirement of IRA pigs of a weight of 30.40 kg. After 18 days a P supply below the requirement resulted in a significantly reduced P level (inorganic) in the serum in both animal groups, with the level of the IRA pigs being significantly below that of the INT animals. For this reason, the P requirement of fattening pigs should be fully covered in experiments with IRA pigs. Although the IRA pigs supplied caecally with ES showed typical appearances of Na deficiency, their Na level in the serum did not differ from that of the other animals.
Electrochemical Sensor Based on Biomimetic Recognition Utilizing Molecularly Imprinted Polymer Receptor

Biological recognition elements such as antibodies, enzymes and aptamers have been utilized as specific receptors to a target molecule in a wide variety of assays and sensors. However, many difficulties for their practical use exist as they lack stability and reusability. Moreover, it is not easy to obtain and prepare sufficient natural bioreceptors. Since practically there are many extraneous inhibitors against biological receptors, scientists have attempted to develop specific recognition elements alternative to bioreceptors. One approach was the synthesis of hosts which possess a structure capable of binding complementary guests. The synthesis of specific recognition sites has been accomplished by coordinating functional monomers around the target molecule, and then cross-linking to position functional monomers around the target molecule (Fig. 1). Such receptors are
Nonlinear kinetic transport of electrons and magnetic field in laser-produced plasmas.

The convection of a magnetic field in the overdense plasma by the Nernst effect is studied with a kinetic description of electron transport. The magnetic field is found to be always strongly coupled to the heat flow, even when the latter is nonlinear (but classical), which places a constraint on flux-limitation schemes in magnetohydrodynamic calculations. The cross-field, Righi-Leduc heat flux is found to require a lower flux limiter than does the inward heat flow into the target.
Mechanical evaluation of aluminum oxide roughened screws in equine third metacarpal bone

vii CHAPTER 1 GENERAL INTRODUCTION . 1 1.1 General Principles of Equine Fracture Repair. 2 1.2 Bone Structure and Function. Bone Healing. 3 1.3 AO Principles of Lag Screw Fixation. 7 1.4 General Consideration of Fracture Repair with Internal Fixation. 8 1.4. 1 Bone-Screw Interface. 9 1.4. 2 Biomechanical Studies on Roughened Implants. 11 1.4. 3 The 5.5 AO Cortical Bone Screw. 12 1.4. 4 The Aluminum Oxide Treated Screw. 13 CHAPTER 2 MECHANICAL EVALUATION OF ALUMINUM OXIDE ROUGHENED SCREWS IN EQUINE THIRD METACARPAL BONE. 15 2.
Soil microbial activity in a Liquidambar plantation unresponsive to CO 2-driven increases in primary production

The indirect responses of soil microbiota to changes in plant physiology effected by elevated atmospheric carbon dioxide have the potential to alter nutrient availability and soil carbon storage. We measured fine root density, microbial biomass nitrogen, rates of nitrogen mineralization and nitrification, substrate utilization by soil bacteria and extracellular enzyme activities (EEA) associated with bulk soil and fine root rhizoplanes within a 3-year period at the Oak Ridge National Laboratory (ORNL) Free Air Carbon Enrichment (FACE) experiment, situated in a Liquidambar styraciflua plantation. Rhizoplane EEA was similar to that of bulk soil. Prior studies have reported a 21% increase in net primary production (NPP) in the enrichment plots and evidence that additional carbon is reaching the soil system, however we observed no response in any of the variables we measured. These results, which contrast with those from other temperate forest FACE sites, suggest that soil characteristics can influence the magnitude and timing of belowground responses. © 2003 Elsevier B.V. All rights reserved.
Some Errors of Perceptual Analysis in Visual Search can be Detected and Corrected

This experiment tried to discover whether people can correct errors which occur because they incorrectly analyse a display to which they have to respond—whether, in fact, they can correct “perceptual” as well as “motor” errors. In a serial, self-paced visual search task, subjects made one response to indicate that a display of five or nine letters contained either of a pair of target letters, and another response when no target was present. Omission errors were much more common than False Identification Errors, but more of them were corrected. Omission errors were detected and corrected faster than False Identification Errors. Typically omission errors were slow responses while False Identification Errors were fast responses. It is possible to deduce that at least some errors resulting from incorrect analysis of a display can be detected and corrected, probably because of an extension of perceptual analysis during, or immediately after, the time when a response to the display is made.
Experiences of adolescents living with cancer: A descriptive qualitative study

This study aimed to explore the experiences of adolescents from Singapore, aged 10–18 years old, living with cancer and their perceptions on how their psychosocial outcomes can be improved. A descriptive qualitative study design was used. Convenience sampling was used to recruit 10 participants from a pediatric oncology ward in a Singapore hospital. Individual semi-structured interviews were conducted. Thematic analysis was used to analyze the data. Five major themes emerged: (1) experience of physical symptoms, (2) emotional response to their condition, (3) changes in social dynamics, and (4) falling behind in academics. The psychosocial outcomes of Singaporean adolescents with cancer could be improved by thorough pain assessments and creating a more conducive hospital environment.
Magnesium Status and Parameters of the Oxidant-Antioxidant Balance in Patients with Chronic Fatigue: Effects of Supplementation with Magnesium

Objective: Magnesium deficiency and oxidative stress have both been identified as pathogenic factors in aging and in several age-related diseases. The link between these two factors is unclear in humans although, in experimental animals, severe Mg deficiency has been shown to lead to increased oxidative stress. Methods: The relationship between Mg body stores, dietary intakes and supplements on the one hand and parameters of the oxidant-antioxidant balance on the other was investigated in human subjects. Results: The study population consisted of 93 patients with unexplained chronic fatigue (median age 38 years, 25% male, 16% smokers and 54% with Chronic Fatigue Syndrome (CFS). Mg deficient patients (47%) had lower total antioxidant capacity in plasma (p=0.007) which was related to serum albumin. Mg deficient patients whose Mg body stores did not improve after oral supplementation with Mg (10 mg/kg/day) had persistently lower blood glutathione levels (p=0.003). In vitro production of thiobarbituric acid reactive substances (TBARS) by non-HDL lipoproteins incubated with copper was related to serum cholesterol (p<0.001) but not to Mg or antioxidants and did not improve after Mg supplementation. In contrast, velocity of formation of fluorescent products of peroxidation (slope) correlated with serum vitamin E (p<0.001), which was, in turn, related to Mg dietary intakes. Both slope and serum vitamin E improved after Mg supplementation (p<0.001). Conclusions: These results show that the lower antioxidant capacity found in moderate Mg deficiency was not due to a deficit in Mg dietary intakes and was not accompanied by increased lipid susceptibility to in vitro peroxidation. Nevertheless, Mg supplementation was followed by an improvement in Mg body stores, in serum vitamin E and its interrelated stage of lipid peroxidation.
Protection against Nasopharyngeal Colonization by Streptococcus pneumoniae Is Mediated by Antigen-Specific CD4+ T Cells

ABSTRACT CD4+ T-cell-dependent acquired immunity confers antibody-independent protection against pneumococcal colonization. Since this mechanism is poorly understood for extracellular bacteria, we assessed the antigen specificity of the induction and recall of this immune response by using BALB/c DO11.10Rag−/− mice, which lack mature B and T cells except for CD4+ T cells specific for the OVA323-339 peptide derived from ovalbumin. Serotype 6B Streptococcus pneumoniae strain 603S and unencapsulated strain Rx1ΔlytA were modified to express OVA323-339 as a fusion protein with surface protein A (PspA) (strains 603OVA1 and Rx1ΔlytAOVA1) or with PspA, neuraminidase A, and pneumolysin (Rx1ΔlytAOVA3). Whole-cell vaccines (WCV) were made of ethanol-killed cells of Rx1ΔlytA plus cholera toxin (CT) adjuvant, of Rx1ΔlytAOVA1 + CT (WCV-OVA1), and of Rx1ΔlytAOVA3 + CT (WCV-OVA3). Mice intranasally immunized with WCV-OVA1, but not with WCV or CT alone, were protected against intranasal challenge with 603OVA1. There was no protection against strain 603S in mice immunized with WCV-OVA1. These results indicate antigen specificity of both immune induction and the recall response. Effector action was not restricted to antigen-bearing bacteria since colonization by 603S was reduced in animals immunized with vaccines made of OVA-expressing strains when ovalbumin or killed Rx1ΔlytAOVA3 antigen was administered around the time of challenge. CD4+ T-cell-mediated protection against pneumococcal colonization can be induced in an antigen-specific fashion and requires specific antigen for effective bacterial clearance, but this activity may extend beyond antigen-expressing bacteria. These results are consistent with the recruitment and/or activation of phagocytic or other nonspecific effectors by antigen-specific CD4+ T cells.
Neuromuscular Training Improves Movement Competency and Physical Performance Measures in 11–13-Year-Old Female Netball Athletes

Abstract Hopper, A, Haff, EE, Barley, OR, Joyce, C, Lloyd, RS, and Haff, GG. Neuromuscular training improves movement competency and physical performance measures in 11–13-year-old female netball athletes. J Strength Cond Res 31(5): 1165–1176, 2017—The purpose of this study was to examine the effects of a neuromuscular training (NMT) program on movement competency and measures of physical performance in youth female netball players. It was hypothesized that significant improvements would be found in movement competency and physical performance measures after the intervention. Twenty-three junior female netball players (age, 12.17 ± 0.94 years; height, 1.63 ± 0.08 m; weight, 51.81 ± 8.45 kg) completed a test battery before and after a 6-week training intervention. Thirteen of these athletes underwent 6 weeks of NMT, which incorporated plyometrics and resistance training. Trained athletes showed significant improvements in 20-m sprint time, 505 agility time, countermovement jump height, and peak power (p ⩽ 0.05, g > 0.8). In addition, trained athletes significantly improved their score in the Netball Movement Screening Tool (NMST) (p < 0.05, g > −1.30); while the athletes also demonstrated increased reach in the anterior and posteromedial directions for the right leg and left leg, and in the posterolateral direction for the left leg only in the Star Excursion Balance Test (SEBT) (p < 0.05, g > −0.03). Control subjects did not exhibit any significant changes during the 6-week period. Significant negative correlations were found between improved score on the NMST and decreased 5-, 10-, and 20-m sprint time, and 505 change of direction time (r > 0.4, p ⩽ 0.05). Results of the study affirm the hypothesis that a 6-week NMT intervention can improve performance and movement competency in youth netball players.
Different Antecedents for Different Knowledge Transfer: a Relational Perspective

From a relational perspective, this study suggests new types of knowledge transfer based on the tenure difference between a knowledge source and a recipient, and explores different motivational mechanism for each type of knowledge transfer. This approach is different from previous ones treating a tenure difference as a cognitive difference that prohibits knowledge transfer. The research model based on the theory of planned behavior was verified using structural equation modeling. The results show that selfefficacy is the strongest antecedent of downward knowledge transfer. On the other hand, in upward knowledge transfer, subjective norm is the most influential. Lastly, in lateral knowledge transfer, expected reciprocity shows a significant effect, but in the negative direction. These results validate the usefulness of the relational approach in understanding the motivational mechanisms of knowledge transfer.
Hypertension associated with bevacizumab.

Digital Object Identifi er: 10.1188/05.CJON. 407-411 As an advanced practice nurse, you care for patients who have a variety of chronic conditions, and you are expected to handle them all. How do you keep up with all of the advances in cardiology, endocrinology, gastroenterology, and infectious disease? You read this column, dedicated to managing a variety of primary care disorders in conjunction with cancer treatment. If you have developed expertise in management of one or more chronic diseases, consider writing for this column. Contact Associate Editor Joyce Marrs, MS, APRN-BC, OCN®, AOCNP, via e-mail at joycemrn@sbcglobal.net. Hypertension Associated With Bevacizumab
Congenital Cataract- Approach and Management Review

Childhood cataract remains a challenge to pediatric ophthalmologists despite recent major breakthrough in surgical techniques and instrumentation. Pediatric cataract is one of the major causes of preventable childhood blindness, affecting approximately 200,000 children worldwide, with an estimated prevalence ranging from three to six per 10,000 live births Congenital cataracts usually are diagnosed at birth. If a cataract goes undetected in an infant, permanent visual loss may ensue. The management of pediatric cataract is a team effort of ophthalmologist ,pediatrician,anaesthetist and parents and should be customized depending upon the age of onset, laterality, morphology of the cataract, and other associated ocular and systemic co-morbidities.This review attempts to summarize the available management options to these patients along with some analytical recommendations to optimise the outcome.
Differentiating Human Embryonic Stem Cells Express a Unique Housekeeping Gene Signature

Housekeeping genes (HKGs) are involved in basic functions needed for the sustenance of the cell and are assumed to be constitutively expressed at a constant level. Based on these features, HKGs are frequently used for normalization of gene expression data. In the present study, we used the CodeLink Gene Expression Bioarray system to interrogate changes in gene expression occurring during differentiation of human ESCs (hESCs). Notably, in the three hESC lines used for the study, we observed that the RNA levels of 56 frequently used HKGs varied to a degree that rendered them inappropriate as reference genes. Therefore, we defined a novel set of HKGs specifically for hESCs. Here we present a comprehensive list of 292 genes that are stably expressed (coefficient of variation <20%) in differentiating hESCs. These genes were further grouped into high‐, medium‐, and low‐expressed genes. The expression patterns of these novel HKGs show very little overlap with results obtained from somatic cells and tissues. We further explored the stability of this novel set of HKGs in independent, publicly available gene expression data from hESCs and observed substantial similarities with our results. Gene expression was confirmed by real‐time quantitative polymerase chain reaction analysis. Taken together, these results suggest that differentiating hESCs have a unique HKG signature and underscore the necessity to validate the expression profiles of putative HKGs. In addition, this novel set of HKGs can preferentially be used as controls in gene expression analyses of differentiating hESCs.
Genome-wide search for atopy susceptibility genes in Dutch families with asthma.

BACKGROUND Atopy is a phenotype associated with asthma that has a heritable component. However, the role of atopysusceptibility genes in the development and expression of asthma and allergic disorders is not understood. OBJECTIVE We sought to study the familial aggregation and co-occurrence of atopic phenotypes within family members of patients with asthma and to identify chromosomal regions that may contain genes that regulate different atopic phenotypes. METHODS In 200 families (n = 1174) ascertained through a proband with asthma, genome-wide screen and linkage analysis was performed for the following atopic phenotypes: (1) specific IgE to common aeroallergens (Phadiatop assay); (2) specific IgE to Der p 1; (3) positive skin test responses to house dust mite; (4) positive skin test responses to 1 or more of 16 allergens; and (5) peripheral blood eosinophils. Results were compared with the linkage results for total serum IgE levels. RESULTS There was clear familial aggregation of atopy. A high total serum IgE level in combination with a positive Phadiatop result or a normal total IgE level in combination with a negative Phadiatop result was found in 56.1% of the probands and 66.9% of the offspring. Several chromosomal regions that showed evidence for linkage to an atopic phenotype (ie, 2q, 6p, 7q, and 13q) also showed evidence of linkage with total serum IgE (Xu et al. Am J Hum Genet 2000;67:1163-73). Specific regions of interest for atopic traits were also detected on chromosomes 11q, 17q, and 22q. CONCLUSIONS Atopic phenotypes show familial aggregation, although family members may differ in expression of atopy. Specific chromosomal regions appear to be important in susceptibility to different phenotypes of atopic responsiveness.
Psychometric validation of a constipation symptom assessment questionnaire.

BACKGROUND Clinical management of constipation is complicated by the lack of a gold standard for evaluation of symptoms. A constipation symptom assessment instrument, the PAC-SYM, was developed to address the patient perspective on the disorder. Instrument content was based on literature review and results of focus groups. METHODS Two hundred and sixteen patients at nine sites participated in a 6-week psychometric evaluation of the PAC-SYM. The final instrument contained 12 items assigned to 3 subscales: stool symptoms, rectal symptoms, and abdominal symptoms. The psychometric properties of this final instrument were assessed. RESULTS Internal consistency and test-retest reliability of the final instrument was high (Cronbach's alpha = 0.89; intraclass correlation = 0.75). Concurrent validity was supported by the correlation with both subject and investigator constipation severity ratings (r= 0.68 and 0.72, respectively; P < 0.0001). Scores were moderately correlated with instruments measuring quality of life. Comparison of treatment responders with nonresponders showed the ability of the instrument to differentiate between groups on the basis of clinical severity (t = -6.12, P < 0.0001 ). Scores changed significantly over time among responders, indicating instrument responsiveness. CONCLUSIONS The PAC-SYM is internally consistent, reproducible under stable conditions, valid, and responsive to change and provides a comprehensive means to assess the effectiveness of treatment for constipation.