Miracle-dz/UniFAR-FTUs huggingface dataset:
Dimethyl(3-oxo-3-phenylpropyl)azanium tetrachloridoferrate(III)

In the title molecular salt, (C11H16NO)[FeCl4], an intramolecular N—H⋯O hydrogen bond in the cation generates an S(6) loop and the conformation of the C(=O)—C—C—N chain is gauche [torsion angle = 57.0 (6)°]. The anion is a near-regular tetrahedron [range of Cl—Fe—Cl angles = 107.93 (8)–112.13 (10)°]. There are no directional inter-ionic bonds in the crystal.
Packaged Q band medium power amplifier

A packaged, medium-power, driver amplifier for the ETSI 42 GHz point-to-point radio band has been designed. The packaged part has a gain of 21 dB, OIP3 of 33 dBm, OIP5 of 28 dBm, noise figure of 5 dB and saturated output power of 25 dBm which, to our knowledge, is the best reported result to date for a packaged Q-band driver amplifier.
Subtyping of Panic Disorder by Symptom Profile

During Phase II of the Cross-National Panic Study, descriptions of the patient's last severe panic attack were collected for 1168 patients. Statistical analysis indicated that patients could be divided into two groups, characterised by the presence or absence of prominent respiratory symptoms. The two groups did not differ on demographic variables or coexisting diagnoses, but they did differ on psychopathology on entry to the study and treatment outcome. The group with prominent respiratory symptoms suffered more spontaneous panic attacks and responded to imipramine, whereas the group without prominent respiratory symptoms suffered more situational panic attacks and responded more to alprazolam. It is important to distinguish spontaneous and situational panic attacks, to aid choice of treatment.
Conflict detection in security policies using Semantic Web technology

The design of efficient and effective techniques for security policy analysis is a crucial open problem in modern information systems. Significant attention has been dedicated in the past to the use of logical tools for the analysis of security policies, but this work has produced a limited impact on enterprise information systems. Important reasons of the limited success of past research were the difficult integration of these approaches with the technological scenario and the limited scalability of many proposals. Nowadays Semantic Web tools are increasingly used in modern information systems. We show how the tools provided by Semantic Web and ontology management technologies offer an adequate basis for the realization of techniques able to support conflict analysis in security policies. Based on the use of these techniques, we propose a solution for two different variants of conflict analysis: (a) Policy Incompatibility, and (b) Separation of Duty Satisfiability. Experiments that test the techniques on large security policies demonstrate the scalability of the approach.
Automatic keyphrase extraction for Arabic news documents based on KEA system

A keyphrase is a sequence of words that play an important role in the identification of the topics that are embedded in a given document. Keyphrase extraction is a process which extracts such phrases. This has many important applications such as document indexing, document retrieval, search engines, and document summarization. This paper presents a framework for extracting keyphrases from Arabic news documents which is based on the KEA system. It relies on supervised learning, Naive Bayes in particular, to extract keyphrases. Two probabilities are computed: the probability of being a keyphrase and the probability of not being a keyphrase. The final set of keyphrases is chosen from the set of phrases that have high probabilities of being keyphrases. The novel contributions of the current work are that it provides insights on keyphrase extraction for news documents written in Arabic. It also presents an annotated dataset that was used in the experimentation. Finally, it uses Naive Bayes as a medium for extracting keyphrases.
Quantifying the eddy diffusivity of the Southern Ocean I : temporal variability

The robustness of Nakamura’s effective diffusivity diagno stic for quantifying eddy diffusivities of tracers in a streamwise-average framewor k is carefully examined in an oceanographic context and the limits of its applicabilit y are detailed. The nearsurface Southern Ocean geostrophic flow, obtained from alti etr c observations, is chosen for particular examination. The temporal variabili ty of the effective diffusivity is examined over the period 1996–2001. Significant va riability is observed on seasonal timescales with a magnitude of ±10–15%, however this variability does not appear to be everywhere well correlated with variat ions in the eddy kinetic energy (EKE), or relatedly, with changes in the wind st ress associated with the Southern Annular Mode: in the region of the ACC variation s in the mean flow u are more significant. It is shown that both in the ACC and equat orward of it there is a reasonable correlation between the eddy diffusivity an d √ EKE/u. JULY 2008 SHUCKBURGH ET Al. 3
Construction and Characterization of Two Recombinant Bacteria That Grow on ortho- and para-Substituted Chlorobiphenyls

ABSTRACT Cloning and expression of the aromatic ring dehalogenation genes in biphenyl-growing, polychlorinated biphenyl (PCB)-cometabolizingComamonas testosteroni VP44 resulted in recombinant pathways allowing growth on ortho- andpara-chlorobiphenyls (CBs) as a sole carbon source. The recombinant variants were constructed by transformation of strain VP44 with plasmids carrying specific genes for dehalogenation of chlorobenzoates (CBAs). Plasmid pE43 carries the Pseudomonas aeruginosa 142 ohb genes coding for the terminal oxygenase (ISPOHB) of the ortho-halobenzoate 1,2-dioxygenase, whereas plasmid pPC3 contains the Arthrobacter globiformis KZT1 fcb genes, which catalyze the hydrolytic para-dechlorination of 4-CBA. The parental strain, VP44, grew only on low concentrations of 2- and 4-CB by using the products from the fission of the nonchlorinated ring of the CBs (pentadiene) and accumulated stoichiometric amounts of the corresponding CBAs. The recombinant strains VP44(pPC3) and VP44(pE43) grew on, and completely dechlorinated high concentrations (up to 10 mM), of 4-CBA and 4-CB and 2-CBA and 2-CB, respectively. Cell protein yield corresponded to complete oxidation of both biphenyl rings, thus confirming mineralization of the CBs. Hence, the use of CBA dehalogenase genes appears to be an effective strategy for construction of organisms that will grow on at least some congeners important for remediation of PCBs.
Structure, Sulfatide Binding Properties, and Inhibition of Platelet Aggregation by a Disabled-2 Protein-derived Peptide*

Background: Binding of Dab2 to sulfatides results in platelet aggregation inhibition. Results: The structure of a Dab2-derived peptide (SBM) embedded in dodecylphosphocholine micelles, characterization of its minimal functional sulfatide-binding site, and its inhibitory platelet aggregation activity were determined. Conclusion: An amphipathic helical region of Dab2 SBM binds sulfatides, leading to platelet aggregation inhibition. Significance: Dab2 SBM may lead to the design of novel aggregatory inhibitors. Disabled-2 (Dab2) targets membranes and triggers a wide range of biological events, including endocytosis and platelet aggregation. Dab2, through its phosphotyrosine-binding (PTB) domain, inhibits platelet aggregation by competing with fibrinogen for αIIbβ3 integrin receptor binding. We have recently shown that the N-terminal region, including the PTB domain (N-PTB), drives Dab2 to the platelet membrane surface by binding to sulfatides through two sulfatide-binding motifs, modulating the extent of platelet aggregation. The three-dimensional structure of a Dab2-derived peptide encompassing the sulfatide-binding motifs has been determined in dodecylphosphocholine micelles using NMR spectroscopy. Dab2 sulfatide-binding motif contains two helices when embedded in micelles, reversibly binds to sulfatides with moderate affinity, lies parallel to the micelle surface, and when added to a platelet mixture, reduces the number and size of sulfatide-induced aggregates. Overall, our findings identify and structurally characterize a minimal region in Dab2 that modulates platelet homotypic interactions, all of which provide the foundation for rational design of a new generation of anti-aggregatory low-molecular mass molecules for therapeutic purposes.
Fast Magnetic Reconnection via Jets and Current Microsheets

Numerical simulations of highly nonlinear magnetic reconnection provide evidence of ultrathin current microsheets. These small-scale sheets are formed by strong exhaust jets from a primary large-scale current layer. The overall size of the secondary microsheet is determined by the thickness of the primary sheet. Preliminary scalings show that the thickness of the microsheet varies linearly with the plasma resistivity. This scaling suggests that microsheets may provide fast reconnection sites in magnetically complex plasmas such as the solar corona and planetary magnetospheres.
Wideband Phase-Reversal Antenna Using a Novel Bandwidth Enhancement Technique

A novel bandwidth enhancement technique for phase-reversal Franklin-type antennas is proposed. Impedance bandwidth enhancement is achieved by combining several coupled modes of the antenna structure through periodic loading provided by radiating crossover dipoles. This technique is explained by the theory of periodically loaded transmission lines. Radiation pattern bandwidth enhancement is achieved by exciting the antenna in its center so as to suppress beam squinting by superposing the tilted beams of two resulting sub-arrays on either side of the feed. An offset parallel stripline (OPS) phase-reversal antenna using these bandwidth enhancement techniques is demonstrated theoretically and experimentally at 35 GHz. The antenna is printed on a thin substrate suspended over a micro-machined conductor-backed cavity for unidirectional radiation. The overall fractional bandwidth of the antenna is increased from 3% to over 11% compared to the conventional design and the antenna efficiency exceeds 80%.
MixPR-An Approach of Combining Content and Links of Web Page

Pagerank was used in systems based on hyperlink structure such as Google. TFIDF was widely used in IR systems based on the vector space model (VSM). It was significative to combine the advantages of two systems. In this paper, we set up a new model by using the content of Web pages and the links among pages. We set up the transition probability matrix, which composed of link information and the relevant value of pages with the given query. The relevant value was denoted by TFIDF. We got the MixPR (mixed pagerank) by solving the equation with the coefficient of matrix. In this model, part of the pages, which would be used to compute the TFIDF, had been downloaded from the Internet firstly, and the link information which started from those pages was stored in local server, too. The importance of the page was determined by content and the links. Experimental results showed that the new model worked well, and the precision approached to the result of the TFIDF did.
Rethinking the terms non-communicable disease and chronic disease

We welcome Ackland et al ’s timely discussion on the terms “non-communicable” and “chronic” disease.1 Their argument is that conditions currently labelled “non-communicable” are in fact “communicable” because the risk behaviours that underlie them are highly transmissible. Thus they argue for a change in label, from “non-communicable diseases” to “chronic diseases”. Their argument, however, confuses one classification system, which is based on cause (namely, communicable diseases compared with non-communicable diseases compared with injuries), with a second classification system, which is based on effect (namely, acute conditions compared with chronic conditions). Their argument also overlooks the growing consensus that chronic conditions include certain communicable diseases, such as HIV/AIDS.2,3 In fact, certain non-communicable conditions are acute in nature, while certain communicable conditions require chronic, ongoing care. For example, HIV/AIDS clearly has an infectious aetiology but requires long term management by the healthcare system. As …
Parametric Models Based on the Adjoint Field Technique for RF Passive Integrated Components

Taking into consideration the variability specific to the nowadays nanotechnologies, the fast extraction of parametric models is a must for the present VLSI and radio-frequency (RF)-integrated-circuit (IC) design environments. The major contribution of the paper is a new, effective methodology for the extraction of parametric compact models for passive RF integrated components with field effects, valid for high-frequency broad range. The proposed numeric method is systematically based on a dual approach, which provides two complementary approximations of the exact solution. Duality is applied both to the spaces where the discrete solution is found as well as to the open boundary conditions. The adjoint field technique is applied in an original manner to the finite-integral techniques to handle the parameter variability of the extracted model. The new method needs much less computing resources for modeling than other numerical methods.
Elevated Levels of LDL-C are Associated With ApoE4 but Not With the rs688 Polymorphism in the LDLR Gene

Introduction: Apolipoprotein E (ApoE) 4 isoform has been associated with elevated levels of cholesterol, low-density lipoprotein cholesterol (LDL-C), and triglycerides (TGs), meanwhile several polymorphisms in the LDL receptor (LDLR) gene have been associated with increased levels of total cholesterol and LDL-C. Material and Methods: We studied 400 women from Southwest Mexico. Anthropometric features and biochemical profile were evaluated, and genotyping of single nucleotide polymorphisms rs429358 and rs7412 in the APOE gene and rs688 in the LDLR gene was determined by TaqMan assays. Results: We found significant association between LDL-C (odds ratio [OR] = 3.3, 95% confidence interval [CI]: 1.9-5.7) and marginal association with TG (OR = 1.7, 95% CI: 1.0-2.9) of atherogenic risk in women carriers of the ApoE4 isoform compared to ApoE3. The TT genotype of rs688 in the LDLR gene was not found to be associated with elevated levels of total cholesterol or LDL-C. Conclusion: Our results show that carrier women of the ApoE4 isoform are more likely to have elevated levels of LDL-C and therefore increased risk of developing atherosclerosis.
An optimization modal for spectral shift estimation

Multiple SAR images of the same area from slightly different slant angles show relative spectral shifts, which is used to improve the slant range resolution by combining their spectra. In the paper, an optimization modal, which maximizes the combined image's amplitude, is proposed to estimate the spectral shift. Simulated data show that the proposed estimation method is more precise than the interferometric method if the two images satisfy the coherence to some extent.
Lung compliance and lung morphology following artificial ventilation in the premature and full-term rabbit neonate.

Rabbit neonates delivered on day 27--30 of gestation were subjected to intermittent positive pressure ventilation (IPPV) for 60 min. Tidal volume was standardized to 10 ml/kg, and the insufflation pressure required to maintain this tidal volume was recorded. The quasistatic compliance of the lung-thorax system, corrected for variations in body weight, was significantly lower in animals delivered on day 27--28 than in those delivered on day 29--30. Immature animals with low lung-thorax compliance (less than 0.40 ml/cm H2O.kg) regularly developed widespread necrosis of bronchiolar epithelium following IPPV, whereas no such lesions were observed in mature animals. It seems probable that these lesions are secondary to overdistension of bronchioles during IPPV and that this abnormal expansion pattern is related to a deficiency of surfactant in the lungs of immature newborn animals.
Dynamics and rapid migration of the energetic 2008–2009 Yellowstone Lake earthquake swarm

Yellowstone National Park experienced an unusual earthquake swarm in December–January, 2008–2009 that included rapid northward migration of the activity at 1 km per day and shallowing of the maximum focal depths from 12 to 2 km beneath northern Yellowstone Lake. The swarm consisted of 811 earthquakes, 0.5 < MW < 4.1, aligned on a N–S 12‐km‐long vertical plane of hypocenters. The largest earthquake of the swarm had a 50% tensile crack‐opening source determined by a full waveform inversion that we interpret as a magmatic expansion component. In addition, GPS data revealed E–W crustal extension coincident with the swarm. Modeling of GPS and seismic data is consistent with E–W opening of ∼10 cm on a N–S striking vertical dike. Our interpretation is that the swarm was induced by magmatic fluid migration or propagation of a poroelastic stress pulse along a pre‐existing fracture zone.
Conformational Thermodynamics of DNA Strands in Hydrophilic Nanopores.

Enhanced sampling techniques spanning a sub-microsecond timescale reveal that a double-stranded DNA dodecamer can be spontaneously encapsulated into (51,0) and (40,0) single-walled carbon nanotubes under the influence of an electric field, leading to hybrids with a 40 kJ/mol enhanced free-energy. The confinement mechanism allows the nucleic acid to retain its mobility, diffusing anisotropically along the endohedral volume, visiting regions of space determined by entropic factors (diameter, free-volume) and linked by a thermodynamical highway. In spite of the energetic similarities between both topologies (4.1× 103 kJ/mol), the biomolecule favours positioning either parallel to the nanopore central axis, (40,0), or in close contact with the solid walls, (51,0), in the latter encasing a hollow cylindrical domain of diameter 1 - 1.5 nm. Precise physiological conditions allow the extrapolation of results to in vivo systems and constitute a novel and thorough contribution to nanotube technology in the areas of nucleic acid encapsulation/delivery and personalized therapeutics.
A novel method for isolating spermatid nuclei from cytoplasm prior to ROSI in the mouse

In the current widely used round spermatid injection (ROSI) protocol for the mouse, the spermatid nucleus is separated from most of the cytoplasm before ROSI by drawing a spermatid in and out of a pipette. This results in the highest rate of normal fertilization. However, this separation method is not always consistent and can be time-consuming. An alternative separation method that cuts away the cytoplasm using the tip of an injection pipette was developed. After removing the cytoplasm, ROSI was performed following both post- and pre-activation protocols and development in vitro and in vivo were examined. The new method consistently removed the bulk of the cytoplasm, as shown by quantifying mitochondria. ROSI without the cytoplasm resulted in significantly higher rates of fertilization than ROSI with the cytoplasm into either post- or pre-activated oocytes. Furthermore, the offspring production rates of ROSI without the cytoplasm were also high (50% and 49% for the post- and pre-activation protocols, respectively). This new method for separating the cytoplasm is an alternative way of producing offspring using ROSI.
Boosting Item Findability: Bridging the Semantic Gap Between Search Phrases and Item Descriptions

Most search engines do their text query and retrieval using keywords. However, vendors cannot anticipate all possible ways in which shoppers search for their products. In fact, many times, there may be no direct keyword match between a search phrase and descriptions of products that are perfect hits for the search. A highly automated solution to the problem of bridging the semantic gap between product descriptions and search phrases used by Web shoppers is developed. By using scalable information extraction techniques from Web sources and a frequent itemset mining algorithm, our system can learn how meanings can be ascribed to popular search phrases with dynamic connotations. By annotating the product databases based on the meanings of search phrases mined by our system, catalog owners can boost the findability of their products.
Encoding structured output values

Many of the Natural Language Processing tasks that we would like to model with machine learning techniques generate structured output values, such as trees, lists, or groupings. These structured output problems can be modeled by decomposing them into a set of simpler sub-problems, with well-defined and well-constrained interdependencies between sub-problems. However, the effectiveness of this approach depends to a large degree on exactly how the problem is decomposed into sub-problems; and on how those sub-problems are divided into equivalence classes. The notion of output encoding can be used to examine the effects of problem decomposition on learnability for specific tasks. These effects can be divided into two general classes: local effects and global effects. Local effects, which influence the difficulty of learning individual sub-problems, depend primarily on the coherence of the classes defined by individual output tags. Global effects, which determine the model's ability to learn long-distance dependencies, depend on the information content of the output tags. Using a canonical encoding as a reference point, we can define additional encodings as reversible transformations from canonical encoded structures to a new set of encoded structures. This allows us to define a space of potential encodings (and by extension, a space of potential problem decompositions). Using search methods, we can then analyze and improve upon existing problem decompositions. In this dissertation, I apply automatic and semi-automatic methods to the problem of finding optimal problem decompositions, in the context of five specific systems (three sequence prediction systems and two semantic role labeling systems). Additionally, I show how linear and log-linear voting can be used to combine structured prediction models that use different problem decompositions, and evaluate the effectiveness of these combined systems.
DNA Probe-Mediated Detection of Resistant Bacteria from Soils Highly Polluted by Heavy Metals

Alcaligenes eutrophus CH34 DNA fragments encoding resistance to Cd2+, Co2+, Zn2+ (czc), or Hg2+ (merA) were cloned and used as probes in colony hybridization procedures with bacteria isolated from polluted environments such as a zinc factory area (desertified because of the toxic effects of zinc contamination) and from sediments from factories of nonferrous metallurgy in Belgium and mine areas in Zaire. From the different soil samples, strains could be isolated and hybridized with the czc probe (resistance to Cd2+, Co2+, and Zn2+ from plasmid pMOL30). Percentages of CFU isolated on nonselective plates which hybridized with the czc and the mercury resistance probes were, respectively, 25 and 0% for the zinc desert, 15 to 20 and 10 to 20% for the two Belgian factories, and 40 and 40% for the Likasi mine area. Most of these strains also carried two large plasmids of about the same size as those of A. eutrophus CH34 and shared many phenotypic traits with this strain. These findings indicated a certain correlation between the heavy-metal content in contaminated soils and the presence of heavy-metal-resistant megaplasmid-bearing A. eutrophus strains.