Miracle-dz/UniFAR-FTUs huggingface dataset:
Recanalization for straight sinus thrombosis through combined mechanical thrombectomy: A case report

Background: Systemic anticoagulation has been the standard treatment for cerebral venous sinus thrombosis (CVT). Although endovascular treatments, including mechanical thrombectomy (MT), have been reported to be effective for CVT, no clear evidence has been established. Case Description: A 51-year-old woman who had been administered oral contraceptive pills was transferred to our hospital with altered consciousness and disorientation. Computed tomography (CT) revealed a hyperdense signal in the straight sinus (StS), and CT angiography revealed a defect in the basal vein and StS, leading to a diagnosis of StS thrombosis. Although systemic anticoagulation through unfractionated heparin was performed, her neurological condition deteriorated, and venous ischemia was observed on CT the next day. She then underwent MT. Partial recanalization was achieved with an aspiration catheter and a stent retriever. Her neurological condition improved tremendously, and venous ischemia was reversed following MT. She was discharged 3 weeks later without neurological deficits with oral anticoagulant. Conclusion: This was a relatively rare case with CVT confined to StS. Immediate combined MT for StS thrombosis can improve venous circulation, make the venous ischemia reversible, and improve patient outcomes, even if it results in partial recanalization.
Doubting leadership: principals shaping a school doubting process within a national curriculum reform

ABSTRACT Success of curriculum reforms calls for both collaborative learning and unlearning processes. Focusing on the latter, school doubting process, an innovative term, is used in this paper as an active framework for organisational unlearning through which educators question their existing mind-sets and unfreeze old approaches to teaching and learning. This qualitative study explores how high school principals shape a school doubting process during the implementation of a national curriculum reform. The study analyses qualitative data from semi-structured interviews with 22 Israeli high school principals who have implemented a national curriculum reform from all school districts. The findings indicate two major themes and sub-themes: (1) Nurturing a collective unlearning culture: (a) restructuring school thinking; and (b) creating safe time and space for school doubting; (2) Building school capacity: (a) creating collective opportunities for knowledge and skill development; and (b) encouraging shared responsibility for innovation.
Brain-Derived Neurotrophic Factor Inhibits the Function of Cation-Chloride Cotransporter in a Mouse Model of Viral Infection-Induced Epilepsy

Well over 100 different viruses can infect the brain and cause brain inflammation. In the developing world, brain inflammation is a leading cause for epilepsy and often refractory to established anti-seizure drugs. Epilepsy generally results from an imbalance in excitatory glutamatergic and inhibitory GABAergic neurotransmission. GABAergic inhibition is determined by the intracellular Cl− concentration which is established through the opposing action of two cation chloride cotransporters namely NKCC1 and KCC2. Brain-derived neurotrophic factor (BDNF) signaling is known to regulate expression of KCC2. Hence we hypothesized that viral induced epilepsy may result from aberrant BDNF signaling. We tested this hypothesis using a mouse model of Theiler’s murine encephalomyelitis virus (TMEV) infection-induced epilepsy. We found that BDNF levels in the hippocampus from TMEV-infected mice with seizures was increased at the onset of acute seizures and continued to increase during the peak of acute seizure as well as in latent and chronic phases of epilepsy. During the acute phase of epilepsy, we found significant reduction in the expression of KCC2 in hippocampus, whereas the level of NKCC1 was unaltered. Importantly, inhibiting BDNF using scavenging bodies of BDNF in live brain slices from TMEV-infected mice with seizures normalized the level of KCC2 in hippocampus. Our results suggest that BDNF can directly decrease the relative expression of NKCC1 and KCC2 such as to favor accumulation of chloride intracellularly which in turn causes hyperexcitability by reversing GABA-mediated inhibition. Although our attempt to inhibit the BDNF signaling mediated through tyrosine kinase B–phospholipase Cγ1 (TrkB-PLCγ1) using a small peptide did not change the course of seizure development following TMEV infection, alternative strategies for controlling the BDNF signaling could be useful in preventing seizure generation and development of epilepsy in this model.
Ecosystem services in Sahelian village landscapes 1952–2016: estimating change in a data scarce region

Burkina Faso and the wider Sahel region have experienced substantial changes in rainfall, population, and landscape use. These changes have altered ecosystem services, the benefits that people receive from ecosystems, and rural livelihoods. However, it is difficult to assess the magnitude of these changes because of missing and fragmented social, agricultural, and ecological data. We estimated changes in 10 key provisioning ecosystem services in rural Burkina Faso between 1952 and 2016. We used a simple model of plausible social-ecological changes to make a historical extrapolation that bridges these data gaps, and assessed historical changes. Our approach combined the interpretation of historic aerial photographs and satellite images, with field observations and interviews. We applied the approach for six villages in two administrative regions for six points in time. We modeled the use of historic ecosystems by analyzing a range of estimates of changes in the generation of each service and its value to people. We found that cultivated ecosystem services have increased 1.5–23 times over the study period, while the non-cultivated ecosystem services firewood, construction material, and medicine have decreased to 66–20% of their previous values. Per capita production of cultivated ecosystem services has remained relatively stable, while the per capita production of all other ecosystem services has decreased, to 54–11% of their 1952 values. Although alternatives are available for some ecosystem services, such as medicine and construction material, there are currently limited alternatives available for other services, such as firewood. Decline in wild food availability and consumption is likely to reduce the nutritional value of rural people’s food. Our analysis of changes demonstrates that shrubs and trees on fields generate many ecosystem services that are key to rural livelihoods, and that efforts to enhance crop yields should maintain shrubs and trees. Our approach for estimating historical ecosystem services may also be useful to apply in other data scarce regions.
Social-mediated frame alignment: A study of menstrual activism in China during the COVID-19 pandemic

ABSTRACT At the early stage of the COVID-19 pandemic in China, an urgent appeal for the donation of menstrual products for female medics was ignored by medical institutions. This soon triggered an unprecedented wave of socially-mediated menstrual activism. By adopting frame alignment as a theoretical framework, this study aims to explore the frames social media influencers utilize to represent topics relating to menstruation and menstrual activism and how the public responded on this taboo issue. We conducted a qualitative content analysis of the frames adopted by WeChat posts. Statistical results showed that news organization accounts used fewer conflict, human interest, and feminism frames than individual and corporate accounts in order to avoid controversy in cyberspace. This study also demonstrated the use of frames of menstrual stigma and public invisibility of menstruation was associated with the pro-feminist attitudes of followers, while the use of efficiency and respect frames was correlated with anti-feminist attitudes. These findings should also provide insights into social-mediated frame alignment strategies for future menstrual and other types of activism.
Design and manufacturing of a disposable endoscope and an overtube using 3-D printing technology

Even after cleaning and disinfecting an endoscope, the possibility of contamination is high and can have negative effects on the health of patients. U.S. Centers for Disease Control (CDC) reports that there are about two million infected victims yearly and about 20,000 succumb to this infection. In recent news, several deaths at the UCLA Ronald Reagan Medical Center have been linked endoscope bacteria contamination. Thus, there is a need for designing an endoscope which will reduce or eliminate the chances of these deadly bacteria entering the body.3-D Printing has been rapidly advancing and can be used as a potential solution for this problem. 3-D printing is being used in printing human tissues and also has a history of printing biocompatible materials, including medical devices. This provides a chance of manufacturing a biocompatible, programmable and disposable endoscope that functions in the same way as present endoscopes, without the risk of contamination.The aim of this project is to design and manufacture a prototype of a 3-D printable, disposable endoscope to eliminate infection rates using different actuation techniques. The preliminary design of endoscope is an active device which can be actuated using various actuation techniques and can be guided through an obstacle course resembling a human colon.
Description of a new species of Hypaeus (Araneae: Salticidae: Salticinae: Amycini) based on integrative taxonomy

ABSTRACT A new species of Hypaeus Simon 1900 is described from French Guiana based on both sexes, Hypaeus olympeae sp. nov. We employed morphological evidence, field observation, as well as the mitochondrial COI rapidly evolving loci to confirm that both males and females belong to the same species. Finally, nine species are newly recorded for the salticid fauna of French Guiana, Cyllodania fasciata (Caporicaco, 1954) syn. nov. is considered junior synonym of Gypogyna forceps Simon, 1900 and 12 COI sequences corresponding to four previously unsequenced Hypaeus species are added to GenBank.http://www.zoobank.org/urn:lsid:zoobank.org:pub:1D7D1869-78B7-4590-90B4-CAD11930B3FB
Computational analysis of 1,3-propanediol operon transcriptional regulators: insights into Clostridium sp. glycerol metabolism regulation

We designed a strategy for the sequencing and bioinformatical characterization of the 1,3-propanediol operon regulator genes from the Colombian Clostridium sp. strain IBUN13A, which is taxonomically related to Clostridium butyricum. Three genes are proposed to be involved in the operon’s transcriptional activity, the dhaS and dhaA genes through a two-component system and the third gene named dhaY, which encodes a putative transcriptional regulator similar to the domains of the dhaS/A system. Phylogenetic analyses indicated that the predicted proteins had a modular structure consisting of domains homologous to different signal transduction systems, but had significant differences concerning their conserved residues, pointing to the possibility that they constitute ancestral domains. In accordance with the prediction of functions, we propose a mechanism of regulation of the proteins studied of the 1,3-propanediol operon of the native strain, as a response to the presence of glycerol in the medium, which provides valuable information on the overall regulation of the glycerol metabolism in Clostridium sp.
Disruptive Behaviors and Intellectual Disability: Creating a New Script

Background Terms currently used to describe the so-called challenging and disruptive behaviors (CBDs) of children with intellectual disabilities (ID) have different connotations depending on guiding contextual frameworks, such as academic and cultural settings in which they are used. A non-judgmental approach, which does not attempt to establish existing categorical diagnoses, but which describes in a neutral way, is missing in the literature. Therefore, we tried to describe CDBs in youth with ID in an explorative study. Methods Interviews with families investigated the CDBs of five youth with Down syndrome. At home, families tracked youth's sleep/wake behaviors and physical activity. Youth were observed in a summer school classroom. The collected information and suggested explanatory models for observed CDBs were reviewed with the families. Results We grouped CDBs as challenging, if they were considered to be reactive or triggered, or unspecified, if no such explanatory model was available. A third category was created for light-hearted CDBs: goofy, acknowledging the right to laugh together with peers. We found some relationships between sleep, physical activity, and CDBs and developed an explorative approach, supporting a child-centered perspective on CDBs. Conclusion The controversial discussions on terminology and management of CDBs in the literature demonstrate the need for a non-judgmental approach. Such an explorative approach, allowing non-professionals to not label, has been missing. The fact that, up to now, the light-hearted behaviors of an individual with ID have not been integrated in commonly-used behavioral checklists as their natural right, proves our concept and indicates that a paradigm change from judgment-based to exploratory-driven approaches is needed.
IET Renewable Power Generation Special Issue: Demand Side Management and Market Design for Renewable Energy Support and Integration Double-deck optimal schedule of micro-grid based on demand-side response

In order to fully consume renewable energies and schedule demand-side resources more hierarchically, a doubledeck optimal schedule model of micro-grid, which connects to power grids and concludes battery energy storage system (BESS), is proposed. Unlike the original peak-valley time-of-use (TOU) price, in the upper layer optimal schedule, the improved TOU price which takes account into the user's satisfaction can express the adjusted loads accurately and the resulting net loads can be treated as a link between upper and lower layer scheduling. For the reason of having no precise model of BESS, the lower model for the goal of minimising the operation cost is solved by action dependent heuristic dynamic programming algorithm that is not relying on the accurate controlled object model. This algorithm is used to obtain the most optimal performance index function and control strategy by the optimal iterative process, which is based on the back propagation neural network used for evaluating the optimal performance index. Analysis of examples and results has been presented to show the effectiveness of the proposed strategies. Nomenclature Indices/sets NW number of wind turbine generators NPV number of solar units NS number of scenarios t (s) index of time (scenario), running from 1 to 24 (NS) Wk (Pk) index of wind turbine (photovoltaic, PV) units, running from 1 to NW (NPV) i (l) index of time or number of the external iteration (internal iteration), running from 1 (0) to the maximum number of iterations (23) j index of shiftable loads Parameters and constants Ps probability of scenarios Pwk . min (Pwk . max) lower (upper) limit value of the output power of the kth wind turbine PPk . min (PPk . max) lower (upper) limit value of the output power of the kth PV unit ms . min () lower limit value of the user's comfort (the user's economy of electricity) Kp coefficient of surrendering part of the profits PB min (PBmax) minimum (maximum) charge and discharge power of battery η charging or discharging efficiency Δt response period Prate rated power output of the battery tmin (tmax) smallest moment range of the allowable responding time t j start (t j ) period to start (end) of the jth shiftable loads Psl j nominal power of the jth shiftable load Cbat comprehensive working cost of BESS ω inertia weight factor C1 (C2) acceleration constant Vi u + 1 (Pi + ) new velocity (position) of particles γ discount factor with 0 < γ ≤ 1 Wc weight coefficient in critic network ε computational accuracy
Smart structures with embedded flexible sensors fabricated by fused deposition modeling-based multimaterial 3D printing

ABSTRACT Smart structures have the advantages of high system integrity and diverse sensing capabilities. However, the labor-intensive and time-consuming fabrication process hinders the large-scale adoption of smart structures. Despite recent attempts to develop sensor-embedded structures using 3D printing technologies, the reported smart structures generally suffer from the complex fabrication process, constrained part size, and limited sensing modality. Herein, we propose a workflow to design and fabricate novel smart structures via multimaterial fused deposition modeling (FDM)-based 3D printing. More specifically, conductive filaments with tailorable mechanical and electrical properties, e.g. piezoresistive effects, were developed. Additionally, the printing process was optimized for processing soft filaments with Young’s modulus around 2 MPa, resolving the issue of filament buckling. Furthermore, the potential applications of the proposed workflow were showcased using three design cases, i.e. biaxial strain sensor, smart tire, and cable-driven soft finger with multiple sensing capabilities. This workflow provides a cost-effective and rapid solution for developing novel smart structures with soft materials. Graphical Abstract
Associations between Self-Objectification and Lifestyle Habits in a Large Sample of Adolescents

The aim of the present study was to test associations between self-objectification and health-related lifestyle habits in a large sample of adolescents. In 2019–2020, a large sample of adolescents (n = 1402, 40.4% boys) participated in the survey and, as a part of a larger study, filled in questionnaires on self-objectification and lifestyle. Self-objectification was assessed using the Self-Objectification Questionnaire (SOQ). The lifestyle questionnaire had three batteries: eating attitudes and behaviors, dietary habits, and questions on harmful behaviors together with time spending patterns: sedentary lifestyle and physical activity. The ages ranged from 15–19 years with a mean age of 16.97 ± 0.46 years. Self-objectification (SO) was associated with a less healthy lifestyle: more frequent dieting and unhealthy eating habits in girls, skipping breakfast, and a lower number of meals per day. Adolescent boys and girls with higher SO demonstrated more frequent smoking and alcohol consumption until they felt dizzy and more frequent consumption of soft drinks, energy drinks, and fast foods. Girls with higher SO demonstrated lower perceived physical activity and longer duration of internet browsing for non-educational purposes. The results of the present study inform healthy lifestyle promotion programs for adolescents, suggesting that including psychoeducation about self-objectification, body functionality, and positive embodiment might be an effective strategy.
E-Sports Competition Analysis Based on Intelligent Analysis System

To improve the analysis effect of e-sports competitions, this paper studies the intelligent analysis methods of e-sports, compares the advantages and disadvantages of various multi-classification methods, and innovatively designs a two-layer SVM classifier structure for four types of motor imagery EEG signals. Moreover, this paper uses the competition data set to test the classification accuracy of the designed double-layer SVM classifier structure and compares it with the DAG-SVM multi-classification method. The research results show that the e-sports competition analysis system based on the intelligent analysis system proposed in this paper has a good e-sports competition analysis effect, and has a good effect in e-sports competition prediction.
Investigations on the Spin States of Two Mononuclear Iron(II) Complexes Based on N-Donor Tridentate Schiff Base Ligands Derived from Pyridine-2,6-Dicarboxaldehyde

Iron(II)-Schiff base complexes are a well-studied class of spin-crossover (SCO) active species due to their ability to interconvert between a paramagnetic high spin-state (HS, S = 2, 5T2) and a diamagnetic low spin-state (LS, S = 0, 1A1) by external stimuli under an appropriate ligand field. We have synthesized two mononuclear FeII complexes, viz., [Fe(L1)2](ClO4)2.CH3OH (1) and [Fe(L2)2](ClO4)2.2CH3CN (2), from two N6–coordinating tridentate Schiff bases derived from 2,6-bis[(benzylimino)methyl]pyridine. The complexes have been characterized by elemental analysis, electrospray ionization–mass spectrometry (ESI-MS), Fourier-transform infrared spectroscopy (FTIR), solution state nuclear magnetic resonance spectroscopy, 1H and 13C NMR (both theoretically and experimentally), single-crystal diffraction and magnetic susceptibility studies. The structural, spectroscopic and magnetic investigations revealed that 1 and 2 are with Fe–N6 distorted octahedral coordination geometry and remain locked in LS state throughout the measured temperature range from 5–350 K.
Infrastructuring Place. Citizen-led Placemaking and the Commons

Abstract A proliferation of participatory spatial practices is emerging in cities, as citizens seek alternative forms of urban governance and land use. Characterised by peer-to-peer production and mediated through the use of digital technologies, these practices are part of a larger narrative about the commons, the ways in which citizens participate in them, and the ways in which knowledge is produced and shared. This case-study uses participatory mapping, group interviews and document analysis to explore how participants in two urban gardening projects make place, and probes whether their practices offer new understandings of community-led placemaking. Results emphasise the important role citizens play in creating, designing and maintaining the commons and demonstrate the ways in which individuals and community groups working outside of a professional urban design context expand placemaking into a vehicle for social change.