Miracle-dz/UniFAR-FTUs huggingface dataset:
Metformin Reduces Left Ventricular Eccentric Re-modeling In Experimental volume Overload in the Rat

Left ventricular hypertrophy (LVH) is often associated with a change in myocardial energy substrate preference from fatty acids to glucose. A possible anti hypertrophic treatment strategy could aim at stimulating or restoring normal myocardial energy metabolism. Metformin, an adenosine monophosphate-activated protein kinase (AMPK) activator used in the management of glucose metabolism in diabetes, is also a fatty acid oxidation stimulator. The effect of metformin on the development of eccentric LVH and ventricular function in chronic left ventricular (LV) volume overload (VO) is unknown. This study was designed to study this question in a VO rat model caused by severe aortic valve regurgitation (AR). Male Wistar rats were divided in four groups (13-15 animals / group): Shams (S) treated or not (C) with metformin (M; 100 mg/kg/d PO) and severe ARreceiving or not metformin. Treatment was started one week before surgery and the animals were sacrificed 9 weeks later. As expected AR rats developed severe eccentric LVH during the course of the protocol. Metformin treatment did not influence the total heart weight. However, LV remodeling associated with the severe VO was severe in ARM than in ARC. Fractional shortening, a marker of systolic function, was significantly higher in ARM compared to ARC group. Metformin also increased the activity of enzymes associated with fatty acid oxidation while inhibiting phosphofructokinase, a glycolytic enzyme. A 2 month treatment with metformin reduced LV eccentric remodeling associated with severe VO and helped maintain a better systolic function.
Identifying security fault reports via text mining

A fault-tracking (bug-tracking) system such as Bugzilla contains fault reports (FRs) collected from various sources such as development teams, test teams, and end-users. Software or security engineers manually analyze the FRs to label the subset of FRs that are security fault reports (SFRs), which indicate a security problem. These SFRs generally deserve higher priority in fault fixing than the not-security fault reports (NSFRs). However, this manual process is time consuming and error-prone (e.g. mislabeling an SFR as an NSFR). To address these important issues, we developed a new approach that applies text mining natural-language descriptions of FRs to train a statistical model on already manually-labeled FRs to identify unlabeled SFRs or SFRs that are manually-mislabeled as NSFRs. A security team can use the model to automate the classification of FRs for large fault databases to reduce the time that they spend on searching for SFRs. We evaluated the model's predictions on a large Cisco software system with over ten million source lines of code. Among a sample of FRs that Cisco software engineers manually labeled as NSFRs, our model successfully classified a high percentage (78%) of the SFRs as verified by a Cisco security team, and predicted their classification as SFRs with a probability of at least 0.98. Our results also indicate that a high percentage (77%) of the SFRs identified by our model is associated with software components that a code-level statistical model predicted to be attack-prone. Such findings provided valuable insights for calling for a future combined approach that exploits both textual information of FRs and code-level information of their associated software components.
Evaluation of Cd(II) Ion Removal from Aqueous Solution by a Low-Cost Adsorbent Prepared from White Yam (Dioscorea rotundata) Waste Using Batch Sorption

An agricultural residue, white yam (Dioscorea rotundata) tuber peel (YTBS), was used for the removal of Cd(II) ion from an aqueous solution using a batch method. The adsorbent was characterized using FTIR, TGA, SEM, EDX, N2 BET, XRD, and XRF. The optimization of sorption variables such as pH, contact time, adsorbent dose, and initial metal ion concentration at 25 °C were also carried out. The results indicated the dependence of sorption on the adsorbate pH and adsorbent dose, while the adsorption system reached equilibrium in 180 min. The sorption kinetics was fitted to three models (pseudo first order, pseudo second order, and Elovich) to validate the kinetics, and the pseudo first order was the best model for the description of Cd(II) uptake. Equilibrium isotherm modelling was also carried out using the Langmuir, Freundlich, and Temkin models, with the Langmuir isotherm giving the best fitting to the experimental results. The maximum loading capacity (qmax) of the adsorbent for Cd(II) obtained from the Langmuir isotherm model was 22.4 mg∙g−1 with an isotherm constant (KL) of 3.46 × 10−3 L·mg−1 and r2 value of 0.99. This result indicates that the YTBS residue was a good adsorbent for the removal of Cd(II) ion from aqueous system.
Effect of Online Behavioral Advertising Implementation on Attitude toward Ad and Purchase Intention in Indonesian E-Marketplace

Internet user increase certainly support e-commerce growth. So some e-commerce companies perform online behavioral advertising (OBA) to get consumers as much as possible. The current study uses retargeted ads as a kind of the latest OBA which most of e-marketplaces in Indonesia implement the ads. Survey in the form of questionnaire from 261 respondents. The respondents were showed by author the example of e-marketplace’s online behavioral advertising picture and video first before answering the questionnaire. It is intended to recall respondents that they have ever seen ads similar to OBA. The result of this study revealed that OBA threatened consumer privacy, so led to cognitive and affective reactance. Perceived ad intrusiveness also had positive effect on perceived threat. OBA led negative attitude toward the ad and finally negative consumer purchase intention toward product which displayed on OBA.
Non-contact video-based heart rate and heart rate variability extraction from different body regions

Cardiovascular diseases are among leading causes of mortality around the world. Long-term monitoring of different cardiac parameters could help in prevention of heart attack or detection of life-threatening arrhythmias. With modern technology development, cheap and accessible methods for different vital signs estimation have emerged. Video-based non-contact heart rate estimation has already been implemented in literature, usually based on individual’s face. In this paper, different body parts were used for estimation including forehead and palm. Heart rate and heart rate variability values were calculated based on photoplethysmography (PPG) signal, which was extracted from video recording. Video recordings were obtained by using professional camera where five individuals were filmed before and after mild exercise. As interframe compression methods degrade the quality of PPG signal, uncompressed video format was used. Separation of the observed signals was executed using Independent Component Analysis (ICA) method for obtaining red, green and blue components from acquired PPG signal. The validation of heart rate and heart rate variability was performed by using 12-channel electrocardiogram recording device. Our results demonstrate that non-contact method for heart rate and heart rate variability estimation shows sufficiently good results, assuming normal light conditions and minimal movement of the subject. Keywords: photoplethysmography (PPG),heart rate, heart rate variability (HRV), independent component analysis (ICA)
Phonebook-centric social networks - dealing with similarities

The popularity of social networks is increasing rapidly. The capabi- lities of mobile phones enable them to participate in social network applications. In addition to the relations between the users of the social network, the phonebooks in the mobile phones also deflne social relations. The key idea behind Phonebook-centric social networks is that Phonebook-centric social networks also provide a synchronization me- chanism between phonebooks of users and the social network. Similarities appear in the system when a contact in a phonebook is similar to a member of the social network. The load and the scalability of the system mainly depend on the number of similarities. By analyzing the data of the phonebook-centric social network implementation Phonebook- mark we experience that the distribution of in- and out-degrees and of the similarities follow a power law. Based on these facts we propose a model, how to estimate the total number of similarities. We verify the accuracy of our estimation empirically and theoretically. For the empirical test we use the data of Phonebookmark collected during a time period of eight months. Finally, we prove an O(NM) upper bound on the total number of similarities, with high probability, i.e. with probability 1 i O(N i∞ M ), where ∞ > 1 is an arbitrarily chosen constant and NM is the number of members of the network.
Investigation of resistance formation mechanisms for contacts to n-AlN and nGaN with a high dislocation density

We studied temperature dependences of the resistivity,   T c  , of Pd-Ti-Pd-Au ohmic contacts to wide-gap semiconductors GaN  n and AlN  n with a high dislocation density. Both   T c  curves have portions of exponential decrease, as well as those with very slight   T c  dependence at higher temperatures. Besides, the Au-Pd-TiPd-n-GaN contacts have a portion of   T c  flattening out in the low-temperature region. This portion appears only after rapid thermal annealing (RTA). In principle, its appearance may be caused by preliminary heavy doping of the near-contact region with a shallow donor impurity as well as doping in the course of contact formation owing to RTA, if the contact-forming layer involves a material atoms of which serve as shallow donors in N III  compounds. The obtained   T c  dependences cannot be explained by the existing mechanisms of current transfer. We propose other mechanisms explaining the experimental   T c  curves for ohmic contacts to GaN  n and AlN  n .
Students' propensity to entrepreneurship: an exploratory study from Greece

This paper seeks to provide evidence on the entrepreneurial propensity of a sample of 364 Greek students, who, at the time of our research, attended classes at a specific University of Economics and Business Studies. Our findings demonstrate that almost half of the students surveyed (46.5%) were positively disposed towards entrepreneurship despite any difficulties that they could probably encounter in the pre- and early-startup phase of their business venture. One third of the respondents (34.7%) reported that they already had an idea of the type of business they desired to establish. However, the majority stated that they were insufficiently prepared to become self-employed. In conclusion, there is much scope to designate and ameliorate entrepreneurship courses across the curricula of the specific university; such efforts could be further enhanced through more targeted longitudinal research in Greece and other South European countries, which face similarly increasing graduates' unemployment levels.
Digital monitoring of mycelium growth kinetics and vigor of shiitake (Lentinula edodes (Berk.) Pegler) on agar medium

Avaliou-se o crescimento e vigor das linhagens LE 96/17, LE 98/51, LE 98/53 e LE 98/56 de Lentinula edodes (Berk) Pegler em diferentes composicoes de meio de cultura. As linhagens foram provenientes da Micoteca do Modulo de Cogumelos da Faculdade de Ciencias Agronomicas, Unesp, Campus de Botucatu. Os isolados foram obtidos por propagacao vegetativa, pela transferencia asseptica do micelio para o meio de cultura de extrato de serragem-dextrose-agar. O crescimento e vigor do micelio foi fotografado diariamente com uma câmera digital, durante a incubacao, ate a colonizacao total da placa de Petri. As imagens foram analisadas pelo programa UTHSCSA ImageTool (freeware), versao 2.0, desenvolvido pela University of Texas Health Science Center, San Antonio, Texas. O modelo estatistico que melhor explicou a cinetica de crescimento miceliano em area (mm2), das linhagens de cogumelos L. edodes, tem como componente deterministico a exponencial de uma funcao Gompertz. O vigor, avaliado atraves da cor do micelio (em escala de tons do cinza), revelou um comportamento similar entre as linhagens, com valor maximo entre o 4o e 5o dia e, em seguida apresentou declinio. Em meios de cultura mais enriquecidos, a velocidade de crescimento das linhagens de L. edodes foi menor e o vigor maior. O monitoramento digital permite uma avaliacao objetiva do crescimento e vigor do L. edodes in vitro.
The new paradigm of rehabilitation : a meta-analysis of the effectiveness of incarceration-based rehabilitation in regards to recidivism reduction.

s, Criminal Justice Abstracts, CINAHL, and NCJRS (National Criminal Justice Reference Service). Terms were searched in each database and results were recorded for relevant research studies that met the criteria of inclusion. Many of the same studies were repeated across multiple databases; this was noted and subsequent appearances of studies already found were disregarded. Terms searched included the following: prison rehabilitation, incarceration-based rehabilitation, drug rehabilitation, prison drug treatment, incarceration-based drug treatment, residential substance abuse treatment, prison substance abuse treatment, incarceration-based substance abuse treatment, RSAT evaluation, RSAT programs, prison therapeutic communities, incarceration based therapeutic communities, Prison Counseling, incarceration based counseling, prison 12step, and incarceration based 12-step.
Theory of vortex sound with special reference to vortex rings

From the fundamental conservation equations of mass, momentum and energy for an ideal fluid of uniform entropy, one can derive a wave equation of aerodynamic sound, which can be reduced to a compact form, called the wave equation of vortex sound with a source term of the form ρ0 div(ω × v) for the acoustic pressure p′, where ρ0 is the undisturbed density. We can consider generation of acoustic waves by vortex-vortex interactions on the basis of this equation. As an axisymmetric problem, we can deduce an expression of the wave profile generated by head-on collision of two coaxial vortex rings, which is characterized as qudrupolar emission. On the other hand, based on the matched asymptotic expansion equivalent to the multipole expansions, one can derive a formula of wave pressure excited by time-dependent vorticity field localized in space. It can be applied to various problems of vortex sound such as an interaction of a vortex-ring with a solid body, and an oblique collision of two vortex rings as well as the head-on collision problem where the same formula as before can be derived. In the case of vortex-body interaction, it is found that the acoustic wave profile can be related to the time derivative of volume flux (through the vortex ring) of an imaginary potential flow around the body (as if like the Faraday’s law), which is characterized as dipolar emission. The case of interaction of a vortex and a sharp edge is studied in terms of the original equation of aerodynamic sound becasue an edge plate is usually a non-compact body. All the wave emissions were detected in the experiments of the author’s group.
Potential control of beans (Phaseolus vulgaris L.) wilt disease using growth regulators, bioagent, antioxidants and essential oils as foliar application under field conditions

The efficacy of some fungicide alternatives as foliar spray was evaluated against bean wilt incidence under field conditions. The fungicide alternatives were indole acetic acid, gibberllic acid, Trichoderma harzianum, vitamins E and C, lemon grass, moringa leaf and thyme oils. The obtained results showed that the applied fungicide alternatives treatments could suppress the incidence of green bean wilt. In the light of the present study, a thought-provoking outcome of the following investigation was reached when the results clearly indicate that 100% suppression of the disease was reached when the bean plants were sprayed with a combination of indole acetic acid 40 ppm + gibberellic acid 40 ppm + T. harzianum 105 cfu/ml. Such an arrest in disease development decreased to 90.5 and 86.4% when the infected plants were treated with indole acetic acid 20 ppm + gibberellic acid 20 ppm + T. harzianum 105 cfu/ml and T. harzianum was combined with gibberellic acid 40 ppm, respectively. It could be hypothetically suggested that combined treatments between growth regulators with the bioagent as foliar spraying might be used practically for controlling such soilborne diseases replacing fungicides treatments. Key words: Bean, biocontrol, foliar formulations, fungicide alternatives, wilt disease control.
Business District Streetscapes, Trees, and Consumer Response

A multistudy research program has investigated how consumers respond to the urban forest in central business districts of cities of various sizes. Trees positively affect judgments of visual quality but, more significantly, may influence other consumer responses and behaviors. Survey respondents from all regions of the United States favored trees in business districts, and this preference was further reflected in positive district perceptions, patronage behavior, and product pricing. An overview of the research is provided, with implications for the economics of local communities.
Application of specific starters for the manufacture of Venaco cheese

L'utilisation de levains lactiques selectionnes specifiques et leur influence sur les caracteristiques microbiologiques, biochimiques et sensorielles ont ete evaluees durant l'affinage du fromage Venaco, un fromage traditionnel corse au lait cru de chevre ou de brebis. Trois levains definis, composes de souches « sauvages » de bacteries lactiques, ont ete testes. Le premier constitue de 2 souches de Lactococcus lactis subsp. lactis (ratio 1:1) etait utilise comme temoin. Le second etait compose de 3 souches, la paire de lactocoques utilisee dans le premier ferment associee a une souche de Lactobacillus paraplantarum (ratio 2:2:1). Le troisieme ferment comprenait la meme paire de lactocoques associee a une souche de Leuconostoc mesenteroides subsp. mesenteroides (ratio 2:2:1). L'experimentation a ete menee dans deux fromageries, la premiere transformant du lait cru de chevre, la seconde du lait cru de brebis. Chaque essai a ete repete 1 fois. Le typage genetique des isolats collectes des fromages a l'aide de la technique Rep-PCR a montre que les souches inoculees dans le lait s'implantaient dans le fromage. Les souches de lactocoques et de Ln. mesenteroides subsp. mesenteroides etaient presentes jusqu'a la fin de l'affinage, la souche de Lb. paraplantarum jusqu'a 15 j d'affinage. Les bacteries lactiques de la microflore indigene etaient retrouvees durant l'affinage, traduisant un certain equilibre entre cette microflore et les souches du levain. Les fromages de chevre et de brebis fabriques avec la souche de lactobacille etaient les plus lipolyses, tandis que l'indice de proteolyse le plus eleve etait obtenu avec le ferment contenant la souche de leuconostoc. Ces modifications physico-chimiques conduisaient a des differences significatives des proprietes sensorielles du fromage evaluees par un test triangulaire.
Optimization of imaging parameter in contrast-enhanced three-dimensional T 1 weighted MRI with fat saturation for head disease

Poster: "ECR 2015 / C-1450 / Optimization of imaging parameter in contrast-enhanced three-dimensional T 1 weighted MRI with fat saturation for head disease " by: "Y. Kanazawa1, T. Miyati2, H. Hayashi1, A. Yagi3, O. Sato3; 1Tokushima/JP, 2Kanazawa/JP, 3Kyoto/JP"
Risk Stratification Model to Predict High-Risk Patients for AdjuvantChemotherapy in Upper Urinary Tract Urothelial Cancer

Objective: Optimal patient selection for adjuvant chemotherapy has not been clarified in upper urinary tract urothelial cancer (UTUC). We aimed to develop a risk model to select candidates for adjuvant chemotherapy after radical nephroureterectomy (RNU). Methods: A retrospective review of 936 patients with UTUC between 1995 and 2015 who received ≥ 2 cycles of platinum-based adjuvant chemotherapy after RNU (n=213) or surgery alone (n=723) was conducted in collaborative institutions. Risk factors for cancer-specific mortality were extracted using the proportional hazard model. The survival benefit in high-risk patients was compared between the groups. Results: At a median follow-up of 1006 days (34 months), disease recurrence, cancer-specific mortality, and allcause mortality were noted in 253 (27.5%), 206 (22.0%), and 285 (30.4%) patients, respectively. On multivariate analysis, baseline serum C-reactive protein (CRP) ≥ 0.32 mg/dL (HR: 1.74, 95% CI: 1.09–2.75, p=0.0201), pathologic T stage ≥ 3 (pT>3) (HR: 2.17, 95% CI: 1.28–3.76, (p=0.0033), cN+ (HR: 2.84, 95% CI: 1.50–5.01, p=0.0021), and lymphovascular invasion (LVI) (HR: 3.94, 95% CI: 2.23–7.17, p<0.0001) were independent predictors of cancer-specific mortality (CSM) in the training set. When they were used to categorize patients into low (0-1 factor) and high-risk groups (2-4 factors), high-risk patients had significantly worse CSM than those with low-risk. In the high-risk patients, 42.3% who received adjuvant chemotherapy had significantly better CSM and all-cause mortality than those who underwent surgery alone. In high-risk patients, multivariate analysis showed adjuvant chemotherapy as an independent prognostic factor for CSM (HR: 0.52) and all-cause mortality (HR: 0.57). Conclusion: CRP, pT>3, cN+, and LVI was useful for identifying high-risk patients.
The Source‐Scanning Algorithm: mapping the distribution of seismic sources in time and space

SUMMARY We introduce a new method, which we call the Source-Scanning Algorithm (SSA), for imaging the distribution of seismic sources in both time and space. Using trial locations and origin times, the method calculates the ‘brightness’ function by summing the absolute amplitudes observed at all stations at their respective predicted arrival times. The spatial and temporal distribution of sources is then identified by a systematic search throughout the model space and time for the maximum brightness. The greatest advantages of this method are that: (1) it exploits waveform information (both arrival times and relative amplitudes) without the need to calculate highfrequency synthetic seismograms; and (2) it requires neither pre-assembled phase-picking data nor any a priori assumptions about the source geometry. A series of tests using synthetic data have shown that this method is robust and can faithfully recover the input source configuration to within 1 grid interval. Finally, we demonstrate the value of the algorithm by locating a typical tremor event with emergent waveforms that occurred during the recent episodic tremor and slip (ETS) sequence in the northern Cascadia subduction zone.
Biomarkers in Leishmaniasis: From Basic Research to Clinical Application

Leishmania is an intracellular protozoan parasite and the etiological agent of a vector-borne disease known as leishmaniasis. This neglected tropical disease exhibits high morbidity and mortality putting at risk people from multiple countries worldwide. It is endemic in 97 countries and 700,000 – 1 million new cases are estimated to occur each year. Leishmaniasis management is very challenging, the symptoms are non-pathognomonic (in both human and canine populations) and the treatments are associated with significant toxicity. Therefore, the need for detection in symptomatic and asymptomatic hosts is important to tackle the dissemination of infection, increasing the need for highly specific biomarkers. In this complex the available disease biomarkers will be addressed in a retrospective manner, focusing on their development from laboratory to their direct use in clinical settings.