Miracle-dz/UniFAR-FTUs huggingface dataset:
Predictive model of bleeding following endoscopic sphincterotomy for the treatment of choledocholithiasis in hemodialysis patients: A retrospective multicenter study

Although hemodialysis (HD) is a strong risk factor for postendoscopic sphincterotomy (ES) bleeding, additional risk factors in HD patients remain unclear. There is no model for predicting post‐ES bleeding risk in HD patients. Therefore, we conducted a retrospective multicenter study to reveal these risk factors and develop a predictive model of post‐ES bleeding in HD patients.
A low-activity ion source for measurement of atmospheric gases by chemical ionization mass spectrometry

Abstract. Most I− -CIMSs (iodide chemical ionization mass spectrometers) for measurement of atmospheric trace gases utilize a radioactive ion source with an initial activity of 10 or 20 mCi of 210Po . In this work, we characterize a 210Po ion source with an initial activity of 1.5 mCi that can be easily constructed from commercially available components. The low level of radioactive activity of this source significantly reduces regulatory burden with storage and shipping relative to higher-activity sources. We compare the sensitivity of the low-activity source (LAS) to a standard 20 mCi source, as a function of carrier gas flow and flow tube pressure, for peroxyacetyl nitrate (PAN), formic acid ( HCO2H ), molecular chlorine ( Cl2 ) and nitryl chloride ( ClNO2 ), using an I− -CIMS. The LAS provides 2 to 5 times less sensitivity than that of the standard source even though the ratio of activity is approximately 13. However, detection limits of less than 2 pptv for the tested compounds are achieved for integration times on the order of a minute. The sensitivity of the LAS is less dependent on the magnitude of the carrier gas than a standard source. In addition, the LAS provides maximum sensitivity at relatively low carrier gas flows. Finally, we demonstrate that the LAS can be used to measure PAN in the remote atmosphere from an aircraft by showing data obtained on the NASA DC-8 during the Atmospheric Tomography (ATom) mission. In summary, the LAS may be an excellent substitute for a standard ion source in short-term field deployments.
Antimicrobial Resistance Profiles of Urinary Escherichia Coli Isolates

ABSTRACT Current knowledge on antimicrobial susceptibility pattern of uropathogens is necessary for appropriate therapy. The objective of this study was to investigate antibiotic susceptibility of 28 clinically isolated strains Escherichia coli, associated with different urinary tract infections. Lowest susceptibility detected was for betalactams ampicillin and ampicillin/sulbactam. High susceptibility was detected for aminoglycoside antibiotics. Approximately half of investigated strain showed multidrug resistance profiles. Plasmid content of E. coli isolates was investigated and participation of detected plasmids in drug resistance was discussed. Our data show the high level of antimicrobial resistance and extended spectrum b—lactamases (ESBL) production amongst the uropathogens causing urinary tract infection.
ASSOCIATION OF TRYPANOSOME INFECTION WITH CIRCULATING ZONA PELLUCIDA (ZP) ANTIBODIES IN WEST AFRICAN DWARF (WAD) GOATS

Sera from 967 adult female West African Dwarf (WAD) goats previously screened for Trypanosome infection by some diagnostic laboratories around Ibadan metropolis, in Southwestern part of Nigeria, were assayed for zona pellucida (ZP) antibodies by the enzyme-linked immunoassay (ELISA) technique. Of the 967 female goats, 534 (55.22%) were positive and 433 (44.78%) negative for Trypanosome infection. Out of those that were positive for Trypanosome infection, 346 (64.79%) and 188 (35.21%) were positive and negative for ZP antibodies respectively. These represented 35.78% and 19.44% of the total number of animals screened respectively. The group that was negative for Trypanosome infections had 149 (34.41%) and 284 (65.59%) positive and negative for ZP antibodies, representing 15.41% and 29.37% of the total number of animals screened, respectively. Seropositivity for ZP antibodies was positively correlated with Trypanosome infection (P<O.OO1). There is the possibility of damage to the blood-ovary barrier as a result of trypanosome infection thereby exposing the zona pellucida to the immune system and being recognized as foreign. The possibility of zona pellucida antibodies as a cause of infertility in domestic animals should always be considered in infertility investigations.
THE USE OF INTERNET AND SOCIAL MEDIA FOR DRUG INFORMATION SERVICES IN PHARMACIES IN YOGYAKARTA PROVINCE: A STUDY OF ASTHMA CARE

Industrial revolution 4.0 is the process of digitizing the industry that leds health services in the era of application of Information and Communication Technology (ICT) called e-health. The application of ICT in Pharmacy is known as e-pharmacy. The role of pharmacists in Drug Information Services by utilizing ICTs has an effect on e-health literacy which ultimately supports the success of patient therapy. This is very important for patients with chronic diseases who are receiving treatment for a long time, one of which is asthma patients. Therefore, this study aims to explore pharmacist perceptions regarding the use of the internet and social media for drug information services, with a case study of services in asthma patients. This research is descriptive with a qualitative approach. Data is collected by interviews using an interview guide that has been validated in a professional judgment. Interviews were conducted with pharmacist participants who provided pharmacy services to asthma patients, who were selected purposively in March to July 2019. Data from interviews were transcribed verbatim, then a thematic analysis was performed. Ethical clearance has been obtained under number 945/ C.16/ FK/ 2019. The results of the study mention the use of the internet and social media indicate the potential capabilities of pharmacists in health services and also the challenges of transformation to the role of pharmacists in the e-pharmacy era. This study also mentions the urgency of establishing regulations regarding e-pharmacy that is driven by the violation from the internet and social media use. Improvement of ICT infrastructure in the pharmacy field as well as the pharmacist's contribution on the provision of drug information for chronic diseases, including asthma, are urgently required.
GENCALC: Software to Facilitate the Use of Crop Models for Analyzing Field Experiments

A number of crop simulation models use as model inputs certain coefficients that account for differences among cultivars. These coefficients, often referred to as genotype coefficients, allow the models to simulate performance of diverse genotypes under different soil, weather, and management conditions. The models therefore can potentially be used to resolve the genotype × environment interaction into underlying coefficients. Gencalc (Genotype Coefficient Calculator) is a software package that facilitates the calculation of these coefficients for use in existing crop models. In Gencalc, the coefficients for a genotype are estimated iteratively by running the appropriate crop model with model input data and approximate coefficients, comparing the model output with actual data, and then altering the coefficients until the simulated and measured values match [. ]
Testing validity inferences of science motivation questionnaire (SMQ-II) instrument: Rasch-based analysis with Indonesian secondary students

Examining science motivation is essential for science learning in the classroom, even more, science motivation is often related to students’ achievement and performance. The test of science motivation has broadly employed and some of the instrument has been translated into a local language where the instrument used. The current study explores the validity evidence of Science Motivation Questionnaire II (SMQ-II) by IRT-Rasch based analysis using Test Analysis Models ‘TAM’ Package v. 3.1-45 in R software from Indonesian context. This study reveals construct validity of SMQ-II instrument based on The Standards for Educational and Psychological Testing using Messick’s (1989) validity theories and construct validity. The data collected from 984 Indonesian middle and high school students. As result, the current study had SMQ-II validity evidence which includes (1) Dimensionality of the instrument using Exploratory Factor Analysis and Rasch-analysis likelihood ratio approach, (2) Expected A Posteriori (EAP) reliability and Weighted Maximum Likelihood Estimation (WLE) reliability, (3) Item fit and item properties, (4) Wright Map using Rasch modeling. The result of construct analysis shows that the instrument was appropriate with a theory where the construct was categorized into five dimensions, all the items of SMQ-II fit the rasch modelling, and the internal reliability of each dimension is categorized as good. In general, the current study suggests that SMQ-II instrument of Indonesian version is adequate to be implemented in Indonesia.
Broad-scale patterns of sex ratios in Patella spp.: a comparison of range edge and central range populations in the British Isles and Portugal

Sex change, or sequential hermaphroditism, occurs in the plant and animal kingdoms and often determines a predominance of the first sex. Our aim was to explore changes in sex ratios within the range of the species studied: Patella vulgata and Patella depressa. The broad-scale survey of sex with size of limpets covered a range of latitudes from Zambujeira do Mar (southern Portugal) to the English Channel. Indirect evidence was found for the occurrence of protandry in P. vulgata populations from the south of England, with females predominating in larger size-classes; cumulative frequency distributions of males and females were different; sex ratios were biased towards males and smallest sizes of males were smaller than the smallest sizes of females. In contrast in Portugal females were found in most size-classes of P. vulgata. In P. depressa populations from the south coast of England and Portugal females were interspersed across most size-classes; size distributions of males and females and size at first maturity of males and females did not differ. P. depressa did, however, show some indications of the possibility of slight protandry occurring in Portugal. The test of sex ratio variation with latitude indicated that P. vulgata sex ratios might be involved in determining the species range limit, particularly at the equatorward limit since the likelihood of being male decreased from the south coast of England to southern Portugal. Thus at the southern range limit, sperm could be in short supply due to scarcity of males contributing to an Allee effect.
Pilumnus Leach (Decapoda:Pilumnidae Samouelle) from Mediterranean and adjacent Atlantic waters: a COI analysis

A molecular taxonomy is presented based on 544 base pair sequences of the mitochondrial COI gene (Palumbi segment) from 141 bristle crabs of the genus Pilumnus from the Mediterranean Sea and adjacent Atlantic Ocean, plus outgroups. The sample includes all currently valid autochthonous Mediterranean species. Six well-supported COI lineages were detected, three of which exclusively comprise representatives of Pilumnus inermis, P. spinifer and P. villosissimus, respectively. On the other hand, crabs that would be attributed to P. hirtellus according to current morphology-based taxonomy were distributed over three COI clades, two of which are interpreted as representing cryptic lineages. We compare our findings to previous analyses using sets of external morphological characters, and discuss the partial mismatch between the morphology- and gene-based classifications.
Dark and Bright Channel Prior Embedded Network for Dynamic Scene Deblurring

Recent years have witnessed the significant progress on convolutional neural networks (CNNs) in dynamic scene deblurring. While most of the CNN models are generally learned by the reconstruction loss defined on training data, incorporating suitable image priors as well as regularization terms into the network architecture could boost the deblurring performance. In this work, we propose a Dark and Bright Channel Priors embedded Network (DBCPeNet) to plug the channel priors into a neural network for effective dynamic scene deblurring. A novel trainable dark and bright channel priors embedded layer (DBCPeL) is developed to aggregate both channel priors and blurry image representations, and a sparse regularization is introduced to regularize the DBCPeNet model learning. Furthermore, we present an effective multi-scale network architecture, namely image full scale exploitation (IFSE), which works in both coarse-to-fine and fine-to-coarse manners for better exploiting information flow across scales. Experimental results on the GoPro and Köhler datasets show that our proposed DBCPeNet performs favorably against state-of-the-art deep image deblurring methods in terms of both quantitative metrics and visual quality.
INHIBITORY CAPACITY OF SODIUM BENZOATE FOR NITRATE‐INDUCED CORROSION OF TIN PLATE

The efficiency of adding three levels of sodium benzoate (100, 1000, 2500 ppm) in inhibiting corrosion of tin by different organic acid solutions at pH = 3.5 containing 125 ppm nitrate, was tested in canned model packs experiments. Model pH = 3.5 solutions consisting of 1% citric acid, or 1% malic acid, or a mixture of 0.8% citric acid + 0.1% malic acid + 0.1% oxalic acid, and containiig 15% sucrose, 500 ppm ascorbic acid and 125 ppm NO3−, were compared with and without the addition of sodium benzoate. The decrease in the nitrate concentration and the increase in the concentration of tin and iron were followed in the canned model solutions throughout suitable storage periods at room temperature. The amounts of dissolved tin and iron were taken as corrosion criteria. Inhibitory efficiency was expressed as the ratio of corrosion rates in solutions with and without the addition of an inhibitor. Results showed that sodium benzoate gave incomplete protection against corrosion of tin by nitrate. Addition of sodium benzoate, e.g., at 1000 ppm, showed that it is most inhibitive in citric acid, less so in malic acid, and least in the 1% citrio-malio-oxalic acid mixture.
Sleep Quality of Cancer Patients Receiving Systemic Treatment: A Cross-Sectional Study

apeutics may lead to the development of various functional problems among the patients. Novel surgical procedures developed to protect organ function employ minimally invasive procedures. However, complex therapies including radiotherapy and chemotherapy are often provided to the patients. Multidisciplinary treatment approaches in cancer patients affect a number of functional fields including physical, psychosocial, and economic areas.1
Phytoestrogen genistein acts as an estrogen agonist on human osteoblastic cells through estrogen receptors α and β

Genistein, a soybean isoflavone, has estrogen‐like activity in mammals, including the prevention of bone loss. However, whether its mechanism of action on bone turnover is distinct from that of estrogen or raloxifene is unknown. Although genistein has been reported to bind both estrogen receptor (ER) isoforms (α and β), little is known concerning differential activation of gene expression via these ER isoforms. To examine this question, comparison of the responses of normal fetal osteoblast (hFOB) cells stably expressing either ERα (hFOB/ERα9) or ERβ (hFOB/ERβ6), to treatment with genistein, 17β‐estradiol (E2) or raloxifene were conducted. In hFOB/ERα9 cells, both genistein and E2 increased the endogenous gene expression of the progesterone receptor (PR), the proteoglycan versican, and alkaline phosphatase (AP), but inhibited osteopontin (OP) gene expression and interleukin‐6 (IL‐6) protein levels. Raloxifene had no effect on these bone markers. Genistein, but not raloxifene, also mimicked E2 action in the hFOB/ERβ6 cells increasing PR gene expression and inhibiting IL‐6 production. To determine whether the gene regulatory actions of genistein in human osteoblast cells occur at the level of transcription, its action on the transcriptional activity of a PR‐A promoter‐reporter construct was assessed. Both genistein and E2 were found to stimulate the PR promoter in the hFOB cell line when transiently co‐transfected with either ERα or ERβ. Whereas hFOB cell proliferation was unaffected by E2, raloxifene or genistein at low concentrations, higher concentrations of genistein, displayed significant inhibition. Together, these findings demonstrate that genistein behaves as a weak E2 agonist in osteoblasts and can utilize both ERα and ERβ. © 2003 Wiley‐Liss, Inc.
The Origin of the Larva and Metamorphosis in Amphibia

All larvae of Ichthyopsida show a great similarity in many important traits. The amphibian larvae, however, have a considerable number of characteristics, which can be considered as comparatively new caenogenetic adaptations. They are most numerous in larvae of Anura. In many fishes having a larval stage in development there is also a metamorphosis more or less similar to the amphibian one. The influence of the thyroid on fish metamorphosis is very variable and never so pronounced as in Amphibia. The dependence of metamorphosis on the thyroid secretion is greatest in Anura. It is much smaller in Urodela and Gymnophiona. In these two groups metamorphosis is a slow and poorly coordinated set of processes. The following conclusions can be drawn from these facts. The Crossopterygian ancestors of Amphibia must have had a larval stage in their development, very similar to the larvae of recent Dipnoi and Urodela. A great evolutionary gain was achieved by Amphibia through the prolongation of the duration of the larval stage, by evolving larval adaptations and by a shortening and synchronization of metamorphosis. Probably some of the morphogenetic processes, forming part of metamorphosis of recent amphibian larvae were dependent on the thyroid hormone secretion in Crossopterygians, just as they depend on it in recent fishes. Other processes developed the dependence on the thyroid comparatively recently. A striking example is the resorption of the tail in Anura. The thyroid gland could not have been a factor in the origin of Tetrapoda from their fresh-water ancestors.
Identification of South Atlantic Hakes (Merluccius australis and Merluccius hubbsi)in Processed Foods by PCR-RFLPs of Cytochrome bGene

Abstract The application of molecular genetics to the identification of fishes is an appropriate technology for quality control and commercial tracking. We have applied a DNA-based methodology to identify the exact species of Argentinean hake included in commercial products. The first test consisted in the PCR amplification of a 122 bp fragment from the cytochrome bgene to assess the presence of DNA from hakes. This test being positive, it was followed by a second test consisting of the amplification and digestion of a PCR fragment of 464 bp from the cytochrome bgene, to determine the identity of the commercialized species. Since a single restriction enzyme provided full diagnosis of the southern Atlantic hake species present in the samples, this methodology would be of great help in traceability across the food-chain that comprises (1) the authentication of Argentinean hake products, (2) the control of fraud to consumers, (3) the industrial advice regarding the labeling of commercial products, and (4) the fishery forensics of Argentinean hakes.
Radiation in the halophytic coenoses of the Peri-Tethys: taxonomy and biogeography of the genus Ita (Coleoptera: Curculionidae)

The weevil genus Ita Tournier, 1878 is revised, its phylogeny inferred and its historical biogeography discussed. Its nomenclatural history is detailed and its taxonomic placement within the Curculionidae is examined; the genus is ascribed to the subfamily Curculioninae, tribe Itini. The type specimens of all the described names referable to this genus were examined and lectotypes designated. Ten new species are described. The synonymy Xeronoma Iablokov-Khnzorian, 1964 = Ita Tournier, 1878 syn. nov. is proposed. The natural history is detailed: all the species for which data are available live in halophytic habitats and are associated with the former family Chenopodiaceae. Inference on phylogeny and hypotheses on historical biogeography are proposed: the genus has probably differentiated not later than the upper Miocene along the south-eastern coasts of the Paratethys; a subsequent radiation occurred as a consequence of the tectonic evolution of the region and through events of dispersion and dispersal.
Constrained LQR Control of Dual Induction Motor Single Inverter Drive

Control of dual induction motor fed by a single voltage source inverter is a challenging task especially during unbalanced load conditions on each motor. Such drive configurations are common, for example, in traction. Conventional control algorithms solve the control of each motor in a separate control loop and the overall control action is designed as a weighted contribution of each control loop. In such a case, the control performance strongly relies on the specific design of weighting coefficients, which should be state dependent and time varying value in majority of cases. In this contribution, we formulate the control problem as an optimization task and investigate the use of state-dependent Riccati equation and predictive control concepts. We show that it is sufficient to consider a simple linear quadratic regulator (LQR) with rule-based predictive controller for current limitation. The proposed control algorithm naturally weights contribution of tracking error of each drive. Moreover, due to high level of symmetry in the system, only two parameters are tuned manually. Experimental testing is used to validate the control algorithm on a laboratory prototype of dual induction motor drive with a rated power of 2 × 4.5 kW.
Disulfide-Depleted Selenoconopeptides: Simplified Oxidative Folding of Cysteine-Rich Peptides

Despite the therapeutic promise of disulfide-rich, peptidic natural products, their discovery and structure/function studies have been hampered by inefficient oxidative folding methods for their synthesis. Here we report that converting the three disulfide-bridged μ-conopeptide KIIIA into a disulfide-depleted selenoconopeptide (by removal of a noncritical disulfide bridge and substitution of another disulfide bridge with a diselenide bridge) dramatically simplified its oxidative folding while preserving the peptide’s ability to block voltage-gated sodium channels. The simplicity of synthesizing disulfide-depleted selenopeptide analogues containing a single disulfide bridge allowed rapid positional scanning at Lys7 of μ-KIIIA, resulting in the identification of K7L as a mutation that improved the peptide’s selectivity in blocking a neuronal (Nav1.2) over a muscle (Nav1.4) subtype of sodium channel. The disulfide-depleted selenopeptide strategy offers regioselective folding compatible with high-throughput c.