Miracle-dz/UniFAR-FTUs huggingface dataset:
Does bedtime matter among patients with chronic pain? A longitudinal comparison study

Abstract Introduction: Chronic pain patients frequently report having sleep disturbances and many tend to stay up during the night and then sleep into the day. Objectives: This study was designed to compare a heterogeneous group of persons with chronic pain who reported typically going to bed between the hours of 9 pm and midnight with those who go to bed at other hours of the day and night. Methods: Two hundred seventy-nine participants were divided between those who reported going to bed between the hours of 9 pm and midnight (N = 205) and those who reported having atypical bedtimes (N = 74) based on pre–post questionnaire data and average pain assessments from a smartphone pain application (app). Results: Those individuals in the atypical bedtime group reported waking up more frequently and getting fewer hours sleep (P < 0.05). These individuals also reported significantly higher pain scores, activity interference, and taking more prescription opioid medication compared with those who had typical bedtimes (P < 0.05). Based on average 3-month daily assessments, those subjects with an atypical bedtime consistently reported more sleep disturbances, pain, activity interference, negative mood, and general worsening conditions over time, and elevated pain catastrophizing, pain-related disability, emotional distress scores, and more prescription medication for pain at 3-month follow-up (P < 0.01). Conclusion: These results support the importance of providers asking patients with pain about what time they typically go to bed at night to gain a greater understanding of their lifestyle habits. Future studies are needed to further determine the importance of maintaining a typical bedtime among patients with chronic pain.
A Investigate of Influence Factor for Tertiary Students’ M-learning effectiveness: Adjust Industry 4.0 & 12-Year Curriculum of Basic Education

Mobile learning (M-learning) as a technology teaching has significant potential to improve student application and comprehension skills. The rapid development of the Internet and the resulting trends applying information available on the Internet have changed the nature of learning and learning behavior patterns of tertiary students. However, insufficient theoretical and empirical research on the effect of M-learning on learning attitude and M-learning effectiveness has been conducted for achieving any reliable understanding of the use of M-learning by tertiary students. This, study was therefore based on the theory of planned behavior, and combined the technology acceptance model and the structural equation model (SEM); it involved 892 tertiary student participants, and developed an empirical research model. The study found that in terms of M-learning acceptance, tertiary students have a positive evaluation and perception of using M-learning, with perceived enjoyment being the most significant factor. In addition, the impact of perceived innovation was significant in helping teachers understand students’ learning outcomes. The teaching material of learning motivations was also significant, indicating that current tertiary students are more likely to value their friends as sources of information. External influences on self-efficacy were also significant, suggesting that teachers must consider the ability of M-learning technology, with particular attention paid to students’ competency with the technology itself, as difficulty of use will reduce students’ willingness to use M-learning.
Towards Thwarting Template Side-Channel Attacks in Secure Cloud Deduplications

As one of a few critical technologies to cloud storage service, deduplication allows cloud servers to save storage space by deleting redundant file copies. However, it often leaks side channel information regarding whether an uploading file gets deduplicated or not. Exploiting this information, adversaries can easily launch a template side-channel attack and severely harm cloud users’ privacy. To thwart this kind of attack, we resort to the k-anonymity privacy concept to design secure threshold deduplication protocols. Specifically, we have devised a novel cryptographic primitive called “dispersed convergent encryption” (DCE) scheme, and proposed two different constructions of it. With these DCE schemes, we successfully construct secure threshold deduplication protocols that do not rely on any trusted third party. Our protocols not only support confidentiality protections and ownership verifications, but also enjoy formal security guarantee against template side-channel attacks even when the cloud server could be a “covert adversary” who may violate the predefined threshold and perform deduplication covertly. Experimental evaluations show our protocols enjoy very good performance in practice.
Zebra fish model of obesity: Relevance to metabolic syndrome

Aim: Recently, the application of zebrafish as an experimental animal model has significantly increased, especially model for obesity. The aim of this research is to reveal the association between high-fat-diet-induced obesity and metabolic syndrome on the zebrafish model. Materials and Methods: Male zebra fish were used in this study. Acclimatization period was performed for 2 weeks when all fish received standard diet intake. Post acclimatization, zebra fish were divided into normal group and obese group. For 4 weeks, normal group received normal diet while the obese group received high-fat diet. Measurement parameters including body mass index (BMI) and blood biochemical parameters. Liver histopathological analysis was performed to observe nonalcoholic fatty liver disease (NAFLD). Results and Discussion: Zebra fish were divided into two groups such as normal group and obese group. Zebra fish were fed following the protocol for 4 weeks. Obese zebra fish showed increased of BMI and blood biochemical parameters compared to the normal group. In addition, excessive fat accumulation in obese zebrafish liver gave a contribution on the elevated NAFLD based on the histopathological study. Conclusion: It can be concluded that high-fat-diet-induced obesity on zebrafish has a strong association with metabolic syndrome.
Audio Compression for Acoustic Sensing

Audio analysis is used in numerous applications such as music classification or environmental monitoring. For latter, data has to be transmitted through a wireless sensor network from the emission sensors to a server. To improve energy efficiency, a prior compression for the data to be sent is suitable. Therefore, a novel data-driven audio compression scheme based on existing work should be designed and analyzed. The concepts used should enable to do a compression for later reconstruction as well as an efficient classification. For classification, a convolutional neural network is used, where two different inputs to this classification network are compared: a model based on the modified discrete cosine transform combined with a band energy computation and one based on the short time fourier transform followed by Mel scaling. Both models showed similar classification accuracy after training. For compression, a simple autoencoder is applied on the coefficients of the modified discrete cosine transform and the reconstruction quality is compared to a Mel inversion model and a simplified version of the CELT codec. A better reconstruction quality is reached by the autoencoder than by the Mel inversion model whereas CELT outperformed every other model.
Ensuring the sustainability of real-time embedded system under both QoS and Energy Constraints

Nowadays, wireless sensor networks (WSNs) are more and more used in applications such as environment monitoring, healthcare monitoring, etc.The challenge in sensor networks is to ensure the sustainability of the system by guaranteeing the required performance level. However, with the limited capacity of finite power sources and the need of guaranteeing a long lifetime of those systems, it is suitable to use energy harvesting which allows to supply low-power electronic systems by converting ambient energy into electric power. Hence, our study is concerned with the problem of soft periodic and aperiodic tasks scheduling in sensor nodes powered by energy harvesters. In this paper, we address this issue by proposing three energy-aware schedulers, namely BG-Green-RTO, BG-Green-BWP and Green-AWP which aim to improve the responsiveness of aperiodic tasks while still guaranteeing the execution of periodic tasks considering their timing and energy constraints. Such algorithms allow to gracefully cope with processing overload and energy starvation. Moreover, a simulation study permits to show their performance.
CIM: Camera in Motion for Smartphone Authentication

The photo response non-uniformity of a smartphone camera is a reliable hardware fingerprint that can be used to authenticate the smartphone owner. This type of camera-based authentication is convenient and of low cost since it requires only pictures taken by a smartphone. However, as shown in this paper, existing camera-based authentication systems are either impractical or subject to fingerprint forgery attacks, in which an adversary intentionally submits forged pictures with fake fingerprints. We propose Camera in Motion (CIM), a practical and reliable camera-based smartphone authentication system. In CIM, a user is asked to move his/her smartphone along a specific route, take pictures of QR codes displayed on the verifier’s interface in burst mode, and submit particular burst pictures to the verifier for authentication. We find that, because burst images are captured in rapid succession, the random noise components of a captured image can be partially preserved across multiple images that are captured in a row. The preserved noise forms a forgery-sensitive noisechain embedded in burst images. We also find that there exists various correlations between the movement of the camera and the noise components of the captured images. The noisechain and these correlations are then explored for forgery detection. We performed extensive experiments with 22 smartphones of 5 different models. Our experiment results show that CIM can achieve 100% true acceptance rate at 0% false acceptance rate in both fingerprint matching and forgery detection.
Comparison of the Effect of Fish Oil and Vitamin E on the Severity of Cyclic Mastalgia

Introduction: One of the most common complaints in women is mastalgia and use of vitamin E is one of the common treatments. Considering the benefits of fish oil and similarity of its mechanisms with vitamin E, this study was performed with purpose of comparing the effects of fish oil and vitamin E on the severity of cyclic mastalgia. Methods: In a double blind clinical trial, 70 women 15 to 49 years with cyclical mastalgia who referred to three clinics in Mashhad city were randomly divided into two groups (35 cases in each group). Fish oil 3 g/day was given to one group and vitamin E 400 IU/day to other group for a period of two months. Severity of cyclic mastalgia was assessed by visual analogue scale and McGill pain questionnaire before intervention and one and two months after treatment. Data were analyzed using SPSS software (version 11.5) and Chi-square test, pair t-test, independent t-test and repeated measures ANOVA. P value less than 0.05 was considered statistically significant. Results: Mean scores of McGill pain questionnaire and mean scores of pain severity using visual analogue scale has decreased before and after intervention in both groups (p 0.05). Conclusion: Satisfaction of taking fish oil in reducing the severity of cyclic mastalgia is more than vitamin E, also fish oil and vitamin E have similar therapeutic effects and could be used as therapeutic alternatives in the treatment of cyclic mastalgia.
How Do Ideal Friend Preferences and Interaction Context Affect Friendship Formation? Evidence for a Domain- General Relationship Initiation Process

This research examined how people’s ideal friend preferences influence the friendship formation process. In an extension of prior research on romantic relationship initiation, we tested whether the match between participants’ ideals and a partner’s traits affected participants’ interest in forming a new friendship in three contexts: evaluating a potential friend’s profile, meeting in-person, and chatting online. Results revealed that participants were more interested in becoming friends with a partner whose traits matched (vs. mismatched) their ideal friend preferences when evaluating his or her profile. After a live interaction, however, the effect of the ideal-perceived trait match manipulation on participants’ friendship interest was substantially reduced in both in-person and online chatting contexts. People’s ideal friend preferences may influence their friendship interest more strongly in descriptive (i.e., indirect) than interactive (i.e., direct) contexts, a finding that mirrors prior results from the romantic domain and documents a role for domain-general relationship initiation processes.
Ant System with Acoustic Communication

— Ant colony optimization is an ant algorithm framework that took inspiration from foraging behavior of ant colonies. Indeed, ACO algorithms use a chemical communication, represented by pheromone trails, to build good solutions. However, ants involve different communication channels to interact. Thus, this paper introduces the acoustic communication between ants while they are foraging. This process allows fine and local exploration of search space and permits optimal solution to be improved.
Forced sex among youth: accrual of risk by gender identity, sexual orientation, mental health and bullying

Abstract Forced sex is a major issue experienced by individuals of all ages, genders, and sexual orientations. Little is known about how LGBQ, transgender, and non-binary young people experience sexual violence. This study examines experiences of forced sex, exploring the intersection of sexual orientation and gender identity, as well as how other socio-demographic and mental health variables are related to differential risk of forced sex. Young people who experience sexual orientation and gender identity marginalization were at elevated risk for experiencing sexual violence. Forced sex was also associated with negative mental health outcomes and bullying victimization. More inclusive sexual violence prevention and support programing for young people and methodological improvements in the way we examine sexual orientation and gender identity in research are needed.
Lewin Increase in REM Time for Divergent Thinking 399

1 Beach, F. A. : Hormones and behavior: A survey of interrelationships between endocrine secretions and patterns of overt response (Hoeber, London 1948). 2 Faure, J. et Loiseau, P.: Action de substances hormonales sur l’activité électrique du cerveau, la respiration, le cycle d’excitabilité et le comportement de la lapine. Rev. neurol. 91: 460-468 (1954). 3 Hartmann, E. : The D state and the menstrual cycle. Recent Adv. biol. Psychiat. 8: 34-35 (1966). 4 Ho, A. : Sex hormones and the sleep of women. In: The association for the psychophysiol. study of sleep: 11th annual meeting, New York 1972. 5 Karacan, I. ; Williams, R. ; Webb, W. ; Webb, M. ; Agnew, H. , and Ross, J. : Sleep and dreaming during late pregnancy and post-partum. Amer. J. Obstet. Gynec. 101: 570-586 (1968). 6 Petre-Quadens, O. ; Barsy, A. de; Devos, J., and Sfaello, A. : Sleep in pregnancy. Evidence of foetal sleep characteristics. J. neurol. Sei. 4: 600-605 (1967).
Complement- and inflammasome-mediated autoinflammation-paroxysmal nocturnal hemoglobinuria

Paroxysmal nocturnal hemoglobinuria (PNH) is an acquired hematopoietic stem cell disorder characterized by complement-mediated hemolysis and thrombosis, and bone marrow failure. Affected cells harbor somatic mutation in X-linked PIGA gene, essential for the initial step in glycosylphosphatidylinositol (GPI) biosynthesis. Loss of GPI biosynthesis results in defective cell-surface expression of GPI-anchored complement regulators CD59 and DAF. The affected stem cells generate many abnormal blood cells after clonal expansion, which occurs under bone marrow failure. Here, we report the mechanistic basis of a disease entity, autoinflammation-paroxysmal nocturnal hemoglobinuria (AIF-PNH), caused by germline mutation plus somatic loss of PIGT on chromosome 20q. A region containing maternally imprinted genes implicated in clonal expansion in 20q-myeloproliferative syndromes was lost together with normal PIGT from paternal chromosome 20. Taking these findings together with a lack of bone marrow failure, the mechanisms of clonal expansion in AIF-PNH appear to differ from those in PNH. AIF-PNH is characterized by intravascular hemolysis and recurrent autoinflammation, such as urticaria, arthralgia, fever and aseptic meningitis. Consistent with PIGT’s essential role in synthesized GPI’s attachment to precursor proteins, non-protein-linked free GPIs appeared on the surface of PIGT-defective cells. PIGT-defective THP-1 cells accumulated higher levels of C3 fragments and C5b-9 complexes, and secreted more IL-1β than PIGA-defective cells after activation of the complement alternative pathway. IL-1β secretion was dependent upon C5b-9 complexes, accounting for the effectiveness of the anti-C5 drug eculizumab for both intravascular hemolysis and autoinflammation. These results suggest that free GPIs enhance complement activation and inflammasome-mediated IL-1β secretion.
The Effects of Workplace Loneliness on Job and Life Satisfaction: the Mediating Role of Leader-Member Exchange

Bu calisma, calisanlarin is hayatlarinda yasadiklari yalnizligin is ve yasam tatmini uzerindeki etkisi ve lider-uye etkilesiminin bu degiskenler arasinda aracilik rolunu belirlemek amaciyla tasarlanmistir. Bu amac dogrultusunda arastirmanin orneklemini Hitit Universitesi’nde gorev yapan toplam 153 idari personel olusturmaktadir. Arastirma sonucunda isyeri yalnizliginin lider-uye etkilesimi ile is ve yasam tatminini negatifyonde etkiledigi tespit edilmistir. Ayrica lider-uye etkilesiminin isyeri yalnizligi ile is ve yasam tatmini arasindaki iliski uzerinde aracilik etkisinin olup olmadigini belirlemek amaciyla hiyerarsik regresyon analizi yapilmistir. Bu analiz sonucunda da lider-uye etkilesiminin isyeri yalnizligi ile is ve yasam tatmini uzerindeki etkisinde aracilik rolu oldugu tespit edilmistir
Low-temperature tolerance and transcriptome analyses during seed germination of Anabasis aphylla

ABSTRACT This study aimed to explore differences in the low-temperature tolerance of a desert plant, Anabasis aphylla, at different seed germination stages during the fall using transcriptome sequencing to identify related genes. The survival rate of the seeds decreased with lower temperatures at different germination stages, and the tolerance of the stages in decreasing order was as follows: imbibition (I) ≈ testa rupture (II) > testa removal (III) > elongation (IV). Superoxide dismutase, peroxidase, and catalase activities and the malondialdehyde content showed a downward trend after stage II. Transcriptome sequencing of seeds, including ripe and dry dominant seeds (W1) and seeds during different germination stages [imbibition (W2), testa removal (W3), and elongation (W4)] was performed. Some genes were downregulated during seed germination, which mainly included cytochrome P450, oleosin, ethylene-responsive transcription factor, and low temperature-induced protein. This study suggests that downregulated of some genes may result in a decrease in low-temperature tolerance.
ISOLATION OF HIGH QUALITY TOTAL RNA FROM VARIOUS TISSUES OF OIL PALM (Elaeis guineensis) FOR REVERSE TRANSCRIPTION QUANTITATIVE REAL-TIME PCR (RT-qPCR)

The extraction of high quality total ribonucleic acid (RNA) has become an essential step for downstream plant molecular biology research. In oil palm, several total RNA extraction protocols have been reported across specific tissues using either conventional method or commercial kits. To our knowledge, there is no specific total RNA extraction method described for oil palm whole fruit which contains lipids, polysaccharides, protein, polyphenols and other secondary metabolites. Here, a modified cetyltrimethylammonium bromidelithium chloride (CTAB-LiCl) method with addition of phenol was established to extract total RNA across various oil palm tissues, especially for whole fruit at eight weeks after anthesis (WAA) and 15 WAA. To assess the extracted total RNA, quality and quantity as well as integrity were evaluated using spectrophotometer and bioanalyser, respectively. It was found that modified CTAB-LiCl method with addition of phenol was able to produce good quality (both A260/A280 and A260/A230 ratios > 1.8) and intact (RIN > 7.4) total RNA. Furthermore, reverse transcription quantitative real-time polymerase chain reaction (RT-qPCR) was successfully performed across all total RNA extracted using two reference genes (PD00569 and pOPEA01332) and one gene of interest, ethylene-responsive transcription factor-3 like, designated as PD00088. The results indicated that the method is suitable for extraction of total RNA from whole fruit as well as other oil palm tissues and is amenable to RT-qPCR.
MULTISKIPGRAPH: A Self-Stabilizing Overlay Network that Maintains Monotonic Searchability

Self-stabilizing overlay networks have the advantage of being able to recover from illegal states and faults. However, the majority of these networks cannot give any guarantees on their functionality while the recovery process is going on. We are especially interested in searchability, i.e., the functionality that search messages for a specific node are answered successfully if a node exists in the network. In this paper we investigate overlay networks that ensure the maintenance of monotonic searchability while the self-stabilization is going on. More precisely, once a search message from node u to another node v is successfully delivered, all future search messages from u to v succeed as well. We extend the existing research by focusing on skip graphs and present a solution for two scenarios: (i) the goal topology is a super graph of the perfect skip graph and (ii) the goal topology is exactly the perfect skip graph.
A Rapid Microtitre Plate Assay for Determining Sensitivity to Photosystem II Herbicides

This paper reports on a microtitre plate version of the 2,6-dichlorophenol-indophenol (DCPIP) reduction assay. DCPIP reduction rates of alfalfa thylakoid membranes were determined by measuring absorbance at 600 nm before and after a 1 min illumination period. The membranes were near light-saturated at intensities above 600 μE m–2 s–1. Saturation of thylakoid membranes with DCPIP occurred above 120 μM. DCPIP reduction rates increased linearly with chlorophyll concentrations from 0.25 to 2 μg. The rate of DCPIP reduction was linear throughout a 2 min illumination period (R2 = 0.99). The assay was sensitive enough to terbacil to differentiate between a 20% change in the I50 concentration. DCPIP reduction rates were sensitive to concentrations of terbacil as low as 100 nM. It only takes 13 minutes to load and read 96 samples using the microtitre plate assay compared to 5.5 h using the conventional procedure.
Quantifying glioblastoma drug penetrance from experimental data

Poor clinical trial outcomes for glioblastoma (GBM) can be attributed to multiple possible causes. GBM is heterogeneous, such that there is a chance of treatment–resistant cells coming to predominate the tumor, and due to the blood brain barrier (BBB) it is also possible that therapy was inadequately delivered to the tumor. Mathematically modeling the dynamics of therapeutic response in patient–derived xenografts (PDX) and fitting the mathematical model to bioluminescence imaging flux data, we may be able to assess the degree to which both drug resistance and drug penetrance are driving varied responses to these therapies.