Miracle-dz/UniFAR-FTUs huggingface dataset:
COMPARATIVE OF FUNGICIDAL EFFICACY AGAINST YELLOW RUST DISEASE IN WHEAT PLANTS IN COMPATIBILITY WITH SOME BIOCHEMICAL ALTERATIONS

Yellow rust of wheat caused by Puccinia striiformis is a destructive disease of wheat. It is present in almost all the wheat growing areas of the world and is a formidable threat to wheat production. The use of chemical fungicides to control plant diseases is an integral component of crop management but should be safety to humans and the environment. Controlling yellow rust disease of wheat by using eight fungicides (TiltP® P, FungshowP® P, AbatchiP® P, CrwanP® P, Sumi-8P® P, PunchP® P, EmnentP® P and MeanarP® P) in wheat spray treatments was studied. Residue analysis of such fungicides in grain and straw of wheat after harvest was carried out. The present investigations were carried out in two different locations during the year of 2017/18 growing season and the results of tested fungicides revealed that minimum disease severity of 1.67 % was recorded with TiltP® P 25% EC. This treatment gave a disease control of 98.07 %, thus increasing the grain yield and 1000 kernel weight by 29.92 and 73.61 %, respectively. It was followed by a disease control of 96.91 % achieved with CrwanP® P 25% EC which gave an increase of 24.39 and 69.34 % in grain yield and kernel weight, respectively. The analysis of total protein and carbohydrates in grains and straw samples of treated plants shown significant differences within all treatments. Data indicated the residue analysis of fungicides in grain and wheat straw exceeded the allowable maximum residue limits (MRLs) value when using fungicides as spray treatment comparing the MRLs on international authorities.
Tinospora crispa methanolic crude extract activates apoptotic pathway of insulin resistant-HepG2 cell lines by improving the insulin sensitivity

This study elucidates the growth inhibition of the insulin resistant-human hepatocellular carcinoma (IR-HepG2) cell lines after treating with Tinospora crispa methanolic crude extract. The IR-HepG2 cell lines were cultured in high glucose-insulin medium, subsequently established by the radiolabelled 2-deoxyglucose assay. The IR-HepG2 (negative control) and WRL68 (normal control) were treated with T. crispa methanolic crude extract and rosiglitazone malate (RM-positive control) respectively. The glucose uptake, downregulated IGF-1R and Bcl-2 protein, and apoptosis mechanism were determined using the immunoblotting method and transmission electron microscope (TEM). Glucose uptake was decreased in IR-HepG2 cell lines, while increased after treated with T. crispa methanolic crude extract and RM. The protein expressions of IR-HepG2 treated with T. crispa was significantly increased (p < 0.05) the insulin receptor (InsR), p-Akt, and GLUT4. IR-HepG2 cell lines stimulated with insulin and treated with T. crispa crude extract were found to activate the apoptosis pathway through the expression of caspases-3, 8, 9 and Bad. Ultimately, the growth of IR-HepG2 cell lines was inhibited via apoptosis after improving cell sensitivity towards insulin and its glucose uptake. Nevertheless, mechanism of T. crispa to induce the effects is still unclear either as a direct ligand or as a cofactor, and it requires further investigations.
Molecular dynamics study of rare-earth doped Mg-silicate nanoparticles in vitreous silica: from the preform to the fiber

Formation of rare-earth doped nanoparticles into silica matrix has been modelized by Molecular Dynamics simulations. Preforms with molar composition 0.10MgO–0.90SiO2 and 0.01EuO3/2–0.10MgO–0.89SiO2 have been investigated to have an insight on the structure and chemical composition of the nanoparticles, as well as the rare-earth ions local environment and their clustering. We have finally applied a uniaxal elongation of the rare-earth doped preform in order to mimic the drawing step that changes a preform into a fiber. We present herein first results on the modification of the nanoparticles size distribution.
Effects of medical insurance system and nursing care on the hospitalization cost effectiveness of acute myocardial infarction patients

Background Acute myocardial infarction is still a burden on Chinese patients. Whether different medical insurance system have any influence on the hospitalization cost and therapeutic effect of acute myocardial infarction patient needs further investigation. Methods In this study, 600 patients were stratified by health insurance status to investigate the cost effectiveness. Results Compared with free medical care, patients with other health insurance status have a significantly lower age (P ˂ 0.05~0.001), the youngest of which is new rural cooperative medical system. The hospital expense, nursing fee, length of stay, daily hospitalization cost, daily drug cost, daily nursing cost and percent of nursing cost of different health insurance status were statistically significant. ANCOVA analyses controlling for age showed that the differences of hospital expenses, nursing fee, length of stay and daily hospitalization cost were still statistically significant. Further studies found that health insurance status was the leading factors influencing length of stay (β =-0.305, P=0.0000001), nursing costs (β =-0.319, P=0.004), daily hospitalization costs (β =0.296, P=0.0001) and occurrence of clinical events (β =-0.186, OR=0.830, 95%CI 0.694-0.993, P=0.041). Conclusions The hospitalization cost, length of stay, nursing work and therapeutic effect of acute myocardial infarction patients are affected by different health insurance status and age.
A theoretical study on the electronic properties of in-plane CdS/ZnSe heterostructures: type-II band alignment for water splitting

Lateral heterostructures fabricated by using two-dimensional (2D) building blocks have attracted a great deal of attention in materials science and device physics. Here we report a novel type of lateral heterostructures within 2D CdS and ZnSe by means of first-principles calculations. Interestingly, the armchair configuration possesses a direct bandgap with type-II band alignment. Simultaneously, the interfacial charge transfer from ZnSe to CdS results in a built-in field which can efficiently separate the electrons and holes. Moreover, the high carrier mobilities are also identified in both armchair and zigzag configurations, even one order of magnitude higher than those of 2D transition metal chalcogenides. More remarkably, both the bandgap and band edges of the lateral heterostructures can meet the requirement of the reduction and oxidation levels in water splitting. These results make these in-plane heterostructures promising candidates for applications in next-generation electronic and optoelectronic devices.
Colorimetric Determination of Paracetamol Using 9-Chloroacridine Reagent: Application to Pharmaceutical Formulations

This paper aims to develop a simple, sensitive and accurate spectrophotometric method for quantitative determination of paracetamol in aqueous medium. The method is based on the reaction between the hydrolyzed paracetamol and 9-chloroacridine reagent (9-CA). The spectra of the product show maximum absorption at 436 nm. Beers law is obeyed in the concentration range of 0.25-11 mg/mL with molar absorptivity value 5.3×10 L/mol/cm. The average recovery percentage (Rec%) is 99.27% and relative standard deviation (RSD) is £ 2.82%. In addition, the stability constant has been determined and the reaction mechanism is proposed. The method has been applied successfully for the assay of paracetamol in pharmaceutical formulations. It is found that the method does not require extraction process and it agree well with British pharmacopeia.
Mesoporous Electron-Selective Contacts Enhance the Tolerance to Interfacial Ion Accumulation in Perovskite Solar Cells

Perovskite-based solar cells are emerging as a potential new leading photovoltaic technology. However, several fundamental aspects of the stability remain unclear. In this Letter, we combine experimental measurements and numerical simulations to show that a mesoporous interface between the perovskite and the electron collection layer mitigates the reversible performance loss associated with the ion migration. We argue that larger interfacial area dilutes the concentration of defects that accumulate as a result of the ion migration within the perovskite under working conditions. Our investigation provides a quantitative description of the mechanism, identifying a critical defect concentration that devices can tolerate without reporting reduced performance.
The impact of retro-cue validity on working memory representation: Evidence from electroencephalograms

Visual working memory (VWM) performance can be improved by retrospectively cueing an item. The validity of retro-cues has an impact on the mechanisms underlying the retro-cue effect, but how non-cued representations are handled under different retro-cue validity conditions is not yet clear. Here, we used electroencephalograms to investigate whether retro-cue validity can affect the fate of non-cued representations in VWM. The participants were required to perform a change-detection task using a retro-cue with 80% or 20% validity. Contralateral delay activity and the lateralized alpha power were used to assess memory storage and selective attention, respectively. The retro-cue could redirect selective attention to the cued item under both validity conditions; however, the participants maintained the non-cued representations under the low-validity condition but dropped them from VWM under the high-validity condition. These results suggest that the maintenance of non-cued representations in VWM is affected by the expectation of cue validity and may be partially strategically driven. DATA AVAILABILITY: The datasets generated/analyzed during this study and experimental script have been added to https://osf.io/qtwc9/.
Association Between FSIP2 Mutation and an Improved Prognosis in Patients With Skin Cutaneous Melanoma Treated With Immune Checkpoint Inhibitors

Background Immune checkpoint inhibitors (ICIs) have been remarkably successful in skin cutaneous melanoma (SKCM), however the response to treatment varies greatly among different patients. Considering that the efficacy of ICI treatment is affected by many factors, we selected the Fibrosheath interacting protein 2 (FSIP2) gene and systematically analyzed its potential as a predictor of ICI treatment prognosis. Methods Patient data were collected from an ICI treatment cohort (n = 120) and The Cancer Genome Atlas (TCGA)-SKCM cohort (n = 467). The data was divided into an FSIP2-mutant (MT) group and FSIP2-wild-type (WT) group according to the FSIP2 mutation status. In this study we analyzed the patients’ overall survival rate, tumor mutational burden (TMB), neoantigen load (NAL), copy number variation (CNV), cell infiltration data and immune-related genes. We used gene set enrichment analysis (GSEA) to delineate biological pathways and processes associated with the prognosis of immunotherapy. Results The prognosis of SKCM patients with FSIP2-MT receiving ICIs was significantly better than that of those with FSIP2-WT. The patients in the FSIP2-MT group had higher tumor immunogenicity and lower regulatory T cell (Treg) infiltration. Results of GSEA showed that pathways related to tumor progression (MAPK and FGFR), immunomodulation, and IL-2 synthesis inhibition were significantly downregulated in the FSIP2-MT group. Conclusion Our research suggests that the FSIP2 gene has the potential to predict the prognosis of ICI treatment. The higher tumor immunogenicity and lower Treg levels may be closely related to the fact that patients with FSIP2-MT can benefit more from ICI treatment.
UPAYA KETERLIBATAN INDONESIA DALAM MENGINTERNASIONALISASIKAN KONSEP BLUE ECONOMY STUDI KASUS: KEPEMIMPINAN INDONESIA DALAM IORA PERIODE 2015-2017

Tulisan ini membahas upaya keterlibatan Indonesia untuk menginternasionalisasikan konsep blue economy dengan mengambil studi kasus pada kepemimpinan Indonesia di IORA periode 2015-2017. Kepemimpinan Indonesia memprakarsai KTT IORA 2017 dan menghasilkan dokumen penting IORA Concord , IORA Action Plan dan Deklarasi Jakarta tentang Ekonomi Biru. Tulisan ini menggunakan metode kualitatif dengan sumber-sumber yang diperoleh secara dokumenter, studi kepustakaan, dan penelusuran data online untuk memperkuat argumentasi penulis. Blue Economy merupakan konsep yang dikembangkan oleh Gunter Pauli yang memadukan unsur ekonomi dan lingkungan. Agenda Indonesia untuk mengedepankan konsep ini untuk meningkatkan ekonominya, mengukuhkan kepentingan politisnya dan memperkuat pengaruhnya di Samudra Hindia, dan menyelamatkan lingkungan. Penelitian menggunakan teori rezim internasional untuk melihat perkembangan blue economy sebagai aturan dan norma yang menjadi pengikat Indonesia dengan IORA dan teori norm life cycles yang membahas tentang siklus hidup norma blue economy yang menjelaskan tentang kaitan Indonesia dengan kemunculan blue economy mulai periode Presiden Susilo Bambang Yudhoyono sampai Presiden Joko Widodo, kepemimpinan Indonesia dalam mempersuasi dan mensosialisasikan blue economy dan internalisasi blue economy dalam ruang lingkup IORA. Penelitian ini juga membahas output yang didapatkan setelah Indonesia bertindak sebagai blue economy norm entrepreneur yaitu mendapatkan pengakuan internasional tentang kemampuan Indonesia, hal ini sejalan dengan usaha Indonesia yang berusaha untuk mewujudkan Poros Maritim Dunia. Kata Kunci : Blue Economy, IORA, Norm entrepreneur, Norm Life Cycles, Rezim Internasional.
Happy Thoughts: The Role of Communion in Accepting and Sharing Epistemically Suspect Beliefs

Why are some epistemically suspect beliefs so popular? People high in communion, either because they want to make others happy, or because they want to display their niceness, might be particularly keen to share ‘happy thoughts,’ beliefs that might make others happy, even if they are epistemically suspect—for instance, that naturopathy works, or that heaven exists. Across six experiments (N = 1596) we found that: (i) people who self-describe as being high on communion (i.e., nice, kind) are more likely to believe and share happier epistemically suspect beliefs, by contrast with people who self-describes as being high on agency (i.e., competent, dominant); (ii) people prefer to share happier beliefs when wishing to appear nice and kind rather than competent and dominant; (iii) sharing happier beliefs does lead to being perceived as nicer and kinder; and (iv) sharing happier beliefs leads to being perceived as less dominant. We also found a consistent positive bias independent of participants’ personality, with happier beliefs being more likely to be shared and believed. Overall, these results suggest that some happy epistemically suspect beliefs could become culturally successful because they allow their sender to signal niceness and kindness.
Predicting Fetal Distress and Admission to Neonatal Intensive Care Unit in Patients With Fetal Growth Restriction by Nomogram: A Retrospective Cohort Study in China

Background: The purpose of this research was to establish prediction model of fetal distress risk and admission to neonatal intensive care unit(NICU) risk in a Chinese population of patients with fetal growth restriction(FGR), to provide a reliable basis for clinical management. Methods: A retrospective analysis of 930 patients were delivered with FGR in the obstetrics and gynecology hospital affiliated from January 1, 2014 to December 30, 2019 at Women’s Hospital, School of Medicine, Zhejiang University, in Hangzhou, and screened out the independent predictors affecting fetal distress and admission to NICU using lasso regression. Multivariable logistic regression analysis was used to establish the nomogram prediction model of fetal distress risk and admission to NICU risk. Discrimination of the predicting model was assessed by the C-index and receiver operating characteristic (ROC) curve, using the bootstrapping validation and the ROC curve to evaluate the Internal validation. Calibration and clinical usability of the predicting model were respectively adopted by calibration curves and decision curve analysis. Internal validation was assessed using the bootstrapping validation. Results: We found that six identified factors associated with fetal distress of patients with FGR: age, gestational week, delivery method, placenta previa, abnormal cord blood flow, and using low molecular weight heparin(LMWH). The application of LMWH during pregnancy could reduce the incidence of fetal distress. Four independent predictors were selected for admission to NICU of patients with FGR: gestational week, delivery method, hypertensive disorders of pregnancy, and intrahepatic cholestasis of pregnancy. The delivery method of cesarean section increased the above risks. Two nomograms were developed and verified accordingly. The two models had good discrimination and good calibration respectively. The decision curve analysis performed that the clinical usability and benefits of the nomograms were the range of 3%-75% and 17%-95%. Conclusions: Two nomograms were the first to predict fetal distress and admission to NICU of patients with FGR. Establishing effective predictive models based on independent predictors could help early diagnosis and evaluation of fetal distress and admission to NICU in patients with FGR.
Barriers to Participation for Litigants in Person in Remote Court Hearings

In response to the significant changes in the operation of the civil justice system necessitated by COVID-19, particularly the swift expansion of the use of remote hearings, the Civil Justice Council issued a rapid consultation on The impact of COVID-19 measures on the civil justice system. Included within the call for responses was a particular plea for evidence relating to how Litigants in Person (LIPs) were experiencing remote hearings. Research at Ulster University (pre-Covid-19) has been examining how LIPs participate in court processes, particularly in the court hearings, to help identify the points at which the LIP’s right to effective participation under Article 6 ECHR could be at risk. This blog post – the content of which has been submitted to the Council’s consultation – reviews our findings, based on face to face hearings, to help determine what ‘effective participation’ should involve, whether via remote or face to face hearings. The content is posted here to help identify the issues to be considered in evaluating how successful remote hearings might be in protecting the LIP’s right to effective participation.
The Cooperation Databank

Publishing studies using standardized, machine-readable formats will enable machines toperform meta-analyses on-demand. To build a semantically-enhanced technology that embodiesthese functions, we developed the Cooperation Databank (CoDa) – a databank that contains2,641 studies on human cooperation (1958-2017) conducted in 78 countries involving 356,680participants. Experts annotated these studies for 312 variables, including the quantitative results(13, 959 effect sizes). We designed an ontology that defines and relates concepts in cooperationresearch and that can represent the relationships between individual study results. We havecreated a research platform that, based on the dataset, enables users to retrieve studies that testthe relation of variables with cooperation, visualize these study results, and perform (1) metaanalyses, (2) meta-regressions, (3) estimates of publication bias, and (4) statistical poweranalyses for future studies. We leveraged the dataset with visualization tools that allow users toexplore the ontology of concepts in cooperation research and to plot a citation network of thehistory of studies. CoDa offers a vision of how publishing studies in a machine-readable formatcan establish institutions and tools that improve scientific practices and knowledge.
Sources of Interference in Memory Across Development

Episodic memory involves remembering not only what happened but also where and when the event happened. This multicomponent nature introduces different sources of interference that stem from previous experience. However, it is unclear how the contributions of these sources change across development and what might cause the changes. To address these questions, we tested 4- to 5-year-olds (n = 103), 7- to 8-year-olds (n = 82), and adults (n = 70) using item- and source-recognition memory tasks with various manipulations (i.e., list length, list strength, word frequency), and we decomposed sources of interference using a computational model. We found that interference stemming from other items on the study list rapidly decreased with development, whereas interference from preexperimental contexts gradually decreased but remained the major source of interference. The model further quantified these changes, indicating that the ability to discriminate items undergoes rapid development, whereas the ability to discriminate contexts undergoes protracted development. These results elucidate fundamental aspects of memory development.
Valorización de residuos de parafinas provenientes de la pirólisis de plásticos por craqueo catalítico

In this research it was studied the effect of the type of catalyst, the reaction temperature and the catalyst/ paraffins weight ratio in the transformation of paraffins waste obtained from the pyrolysis of plastics by catalytic cracking. It was chosen the Zeolite Y and Zeolite ZSM-5 as catalysts, the catalyst/paraffin weight ratios of 0.4:1 and 0.20:1 and the reaction temperatures of 400˚C and 440˚C. The catalytic cracking reaction of the paraffins was carried out in a fixed bed reactor. By the statistical analysis it was determined that the type of catalyst has the most outstanding effect, thus with the Zeolite ZSM-5 an average yield of 27.43% was reached. In contrast, with the Zeolite Y was obtained a 13.10%. In addition, it was found that the yield increased by 1.2% when a temperature of 400 ° C was used compared to 440°C. The catalyst/paraffin weight ratio does not significantly affect the yield. According to the analyzes performed by gas chromatography to the liquid reaction products, it would be expected that through this process products like diesel, Jet A-1 aviation fuel and gasoline could be obtained.
Role of Human Chorionic Gonadotropin Level After Molar Suction Curettage in Anticipating Post-molar Trophoblastic Neoplasia in Vietnam

Objective: The objective of the study was to determine the trophoblastic neoplasia (TN) anticipating the value of beta-human chorionic gonadotropin (β-hCG) concentration 2 weeks after molar suction curettage and its concentration ratio at pre-removal versus 2-week post-removal. Materials and Methods: A nested case–control study in hydatidiform mole patients admitted to Tu Du Hospital from July 2016 to December 2017 was conducted. Patients were divided into two groups with all 123 cases of TN (case group) and 247 random cases of spontaneous molar remission (control group). Receiver operating curve was applied to find the β-hCG factors of the most predictive value. Results: The average length of time for TN diagnosis was 6.2 weeks as per the Federation of Gynecology and Obstetrics 2002. The ideal cutoff points of β-hCG concentration 2 weeks and 4 weeks after molar suction curettage for anticipating TN were 700 mIU/mL (sensitivity: 79% and specificity: 69%) and 148 mIU/mL (sensitivity: 83% and specificity: 84%), respectively. The ideal cutoff points of β-hCG ratio at pre-removal versus 2-week and 4-week post-removal for anticipating TN were 340 (sensitivity: 77% and specificity: 64%) and 1345 (sensitivity: 79% and specificity: 84%), respectively. Conclusion: β-hCG concentration 2 weeks after molar removal is a good factor to early anticipates the risk of TN switch in hydatidiform mole patients.