Miracle-dz/UniFAR-FTUs huggingface dataset:
LEARNING FROM ERRORS 1 Learning from Errors : Students ’ and Instructors ’ Practices , Attitudes , and Beliefs

In some educational contexts, such as during assess ment , it is essential to avoid errors. In other contexts, however, generating an error can foster v aluable learning opportunities. For instance, generating errors can improve memory for correct an swers. In two surveys conducted at three large public universities in North America, we inve stigated undergraduate students’ and instructors’ awareness of the pedagogical benefits of generating errors, as well as related practices, attitudes, and beliefs. Surveyed topics in luded the incorporation of errors into learning activities, opinions about the consequence s of studying errors, and approaches to feedback. Many students had an aversion towards ma king errors during learning and did not use opportunities to engage in errorful generation, yet studied or analysed errors when they occurred. Many instructors had a welcoming attitude towards e rrors that occur during learning, yet varied in providing students with resources that facilitat e errorful generation. Overall, these findings reveal the prevalence of an ambivalent approach to errors: Students and instructors avoid generating errors but prioritise learning from them when they occur. These results have important implications for the implementation of pr etesting, productive failure, and other errorfocused learning techniques in educational contexts .
Pregnancy Associated Breast Cancer: Clinicopathological profile and Management in the Department of Gynecology - Obstetrics II of the HASSAN II Teaching Hospital of Fez (Morocco)

Background: Breast cancer represents in our department the most frequent cancer among gyneco mammary cancers. Its association with pregnancy rarely observed is reported to be the most common form of cancer diagnosed during pregnancy. Pregnancy? associated breast cancer (PABC) refers to breast cancer (BC) diagnosed during pregnancy, lactation, or in the postpartum period. We made this study in order to describe the clinicopathological profil of PABC and the management in our context. Methodology: This is a retrospective study on 14 patients with Pregnancy? associated breast cancer managed in the service of Gynecology - Obstetrics II of the Hassan II teaching hospital in Fez (Morocco). We defined Pregnancy? associated breast cancer as any breast cancer discovered during an active pregnancy or during the 12 months following the pregnancy. Results: The average age was 34,64years old. The most represented age group was that of 30 to 39 years old. 11 patients (78,6%) were pregnant and 3 (21,4%) were in postpartum period. Most of the patients (8/14: 57,1%) presented for breast nodule discovered by sefl-palpation Clinically, most of the tumors was at the stage of T3N1MX and T2N1MX. The breast ultrasound was in favor of lesions classified ACR5 in 57,1% of cases versus ACR4 in 42,9% of cases. Non-specific type invasive carcinoma was the most frequent histologic type (11/14 either 78,6% of cases). The majority of patients (78,6%) had an intermediate invasive grade of SBR (grade II). The frequent immunohistochemical type of the invasive carcinomas was Luminal B (57,1%). Chemotherapy was performed in 100% of cases. Among those in pregnancy 6 was neo-adjuvant (42,9%) and 8 was adjuvant (57,1%) at the median term of 24 weeks of gestation with extrems of 14 and 38 weeks of gestation. No patient was treated with herceptin during pregnancy. Adjuvant hormone therapy has been introduced in 6 patients’ treatment (42,9%). Radiotherapy was performed in all cases and no patient received radiotherapy during pregnancy. We recorded a death rate of 21,5%. Conclusion: The diagnosis PABC during pregnancy requires a good sense approach to management with careful consideration given at all stages to the needs of the mother and risks to the fetus. Pregnancy might prevent the approach of optimal treatment as the cancer might prevent the good evolution of the pregnancy.
Enhanced Electrochemical Performances of Porous MnO as Anode material for Lithium Ion Batteries Prepared by Magnetic Field Assisted Hydrothermal Method

Porous MnO prismoid was prepared by the magnetic-field assisted hydrothermal method. Influences of magnetic field (H = 2T) on microstructure, morphology, and electrochemical properties were studied. Under the action of magnetic field, X-ray diffraction results indicate that the crystal structure of MnO microprism is in accord with that of MnO microcube. SEM and TEM images suggest that the average grain size of MnO microprism decreases slightly. The electrochemical measurements show that MnO prismoid represents better than MnO microcube as the anode material for Lithium-ion batteries, which can be explained by the fact of modified crystal structure under the assistance of magnetic field.
Study on Mutation of Identifying Characters Indica-Japonica rice Irradiated by high Space Condition

The cultivated Japonica rice“Zhongzuo 59”seeds were carried by high space balloon under high space conditions of 30～35Km from sea level for 8 hours in 1998.In this paper,it were investigated that the variation of 6 characters identified between Indica-Japonica in the 60 mutant lines of the SP14 generation by selfed.The results as follow.The variation were continual in the hull colour reaction of phenol,the days of seed germination,the resistance to KClO 3,length of seed peak hair,ratios of length to width of seed.But the both extremity of the variation range can be clarified two types of Indica and Japonica;The vatiation were continual in male sterility of hybrid F 1 that the mutants crossed with Indica tester.The range of variation of F 1 pollen fertility were 0.72%～96.22%. This results indicated that compatibility of hybrid in the mutants were mutation.There were 8 mutant lines in the 60 mutant lines investigated showed Indica type in the 6 identifying characters,others had Japonica or middle between Japonica and Indica characters.So,it were considered that the Indica type rice and middle between Japonica and Indica can be mutation from japonica which treated by high space condition.
Social Capital: The Role of Group Size and Heterogeneity

Article History Published Online: 17 August 2020 Group size and heterogeneity are important issues in the literature on cooperation. This study seeks to understand how group size and heterogeneity impinge on trust and cooperation using a repeated trust game. We find several interesting results. First, as expected in any finitely repeated game, subjects as individuals and in a group become less trusting and less reciprocal as the rounds progress. Second, the nature of cooperation also matters in understanding the factors influencing cooperation in a group. Third, income and caste heterogeneity affect cooperation and trust. We see a U-shaped relation between trust and group size that indicates the existence of threshold size of the groups for building social capital . Regarding the validity of these experimental results with the primary survey, the study finds that in villages where heterogeneity is negligible, people share a set of similar socio-cultural attributes that promotes cooperation as a cost-effective collective outcome. Thus, our experimental results are significantly valid in the context of community-based natural resource management. Further social capital like trust acts as a link between the group size, heterogeneity and cooperation. Therefore, policymakers should give due importance of the underlying issues related to group size and heterogeneity (that influence trust and cooperation.)
Isozyme Polymorphism in Lens (Leguminosae)

Crossability and cytological studies have led to a recent taxonomic revision of Lens. Starch gel electrophoresis of isozymes was employed to clarify the relationships among the revised Lens taxa and provide further insight as to the origin of the cultivated lentil, L. culinaris ssp. culinaris. The 14 enzymes studied yielded scorable products of 25 putative isozyme loci, 16 of which were polymorphic. Isozyme polymorphism within accessions was extremely low while greater amounts of variation were observed among accessions and even greater amounts among taxa. A high degree of electrophoretic similarity was found among L. culinaris ssp. culinaris, L. culinaris ssp. orientalis, and L. culinaris ssp. odemensis. Lens nigricans ssp. ervoides possessed more allozymes in common with all three L. culinaris subspecies than with L. nigricans ssp. nigricans. Similarly, a differentiated cytotype of ssp. nigricans showed more electrophoretic affinity with all three L. culinaris subspecies and ssp. ervoides than with the remaining accessions of ssp. nigricans which emerged as the most electro- phoretically distinct group. On the basis of the electrophoretic data alone, ssp. orientalis and ssp. odemensis are the most likely progenitors of the cultivated lentil, ssp. culinaris.
Regional atmospheric reanalysis activities at Deutscher Wetterdienst: review of evaluation results and application examples with a focus on renewable energy

Abstract. Based on the numerical weather prediction model COSMO of Germany's national meteorological service (Deutscher Wetterdienst, DWD), regional reanalysis datasets have been developed with grid spacing of up to 2 km. This development started as a fundamental research activity within the Hans-Ertel-Centre for Weather Research (HErZ) at the University of Bonn and the University of Cologne. Today, COSMO reanalyses are an established product of the DWD and have been widely used in applications on European and national German level. Successful applications of COSMO reanalyses include renewable energy assessments as well as meteorological risk estimates. The COSMO reanalysis datasets are now publicly available and provide spatio-temporal consistent data of atmospheric parameters covering both near-surface conditions and vertical profiles. This article reviews the status of the COSMO reanalyses, including evaluation results and applications. In many studies, evaluation of the COSMO reanalyses point to an overall good quality and often an added value compared to different contemporary global reanalysis datasets. We further outline current plans for the further development and application of regional reanalyses in the HErZ research group Cologne/Bonn in collaboration with the DWD.
POCUS series: point-of-care lung ultrasound in patients with COVID-19

This article is part of the point-of-care ultrasound (POCUS) series During the Coronavirus Disease 2019 (COVID-19) pandemic, we have been managing large numbers of infected patients whilst maintaining high-quality healthcare In this article we aim to provide a short and practical description on how point-of-care lung ultrasound can be of use to facilitate diagnosis and treatment in critically ill patients diagnosed with COVID-19
REPRODUCIBILITY IN A.I. FOR BIOMEDICAL RESEARCH: AN APPLICATION TO PARKINSON’S DISEASE by CHRISTIAN LEE MCDANIEL

Increased prevalence of smartphones and wearable devices has facilitated the collection of triaxial accelerometer data for numerous Human Activity Recognition (HAR) tasks. Concurrently, advances in the theory and implementation of long short-term memory (LSTM) recurrent neural networks (RNNs) has made it possible to process this data in its raw form, enabling on-device online analysis. In this two-part experiment, we have first amassed the results from thirty studies and reported their methods and key findings in a meta-analysis style review. We then used these findings to guide our development of a start-to-finish data analysis pipeline, which we implemented on a commonly used open-source data set in a proof of concept fashion. The pipeline addresses the large disparities in model hyperparameter settings and ensures the avoidance of potential sources of data leakage that were identified in the literature. Our pipeline uses a heuristic-based algorithm to tune a baseline LSTM model over an expansive hyperparameter search space and trains the model on standardized windowed accelerometer signals alone. We find that we outperform other baseline models trained on this data and are able to compete with benchmark results from complex models trained on higher-dimensional data.
Sentiment Analysis of the Customer Reviews and Opinion Verdict on Probabilistic Analysis

: This paper is intended to examine and analyze the market trends and the scenarios occurring according to the product sales and reviews and same goes with the sentiments of the users regarding the services provided by the service providers. The use of concept of Knowledge Discovery in Database and Opinion mining has been used to give the feedback which will eventually help the seller/service provider in analyzing market and its need for better products and services.
Displacement Imaging During Focused Ultrasound Median Nerve Modulation: A Preliminary Study in Human Pain Sensation Mitigation

Focused ultrasound (FUS)-based viscoelastic imaging techniques using high frame rate (HFR) ultrasound to track tissue displacement can be used for mechanistic monitoring of FUS neuromodulation. However, a majority of techniques avoid imaging during the active push transmit (interleaved or postpush acquisitions) to mitigate ultrasound interference, which leads to missing temporal information of ultrasound effects when FUS is being applied. Furthermore, critical for clinical translation, use of both axial steering and real-time (<1 s) capabilities for optimizing acoustic parameters for tissue engagement are largely missing. In this study, we describe a method of noninterleaved, single Vantage imaging displacement within an active FUS push with simultaneous axial steering and real-time capabilities using a single ultrasound acquisition machine. Results show that the pulse sequence can track micron-sized displacements using frame rates determined by the calculated time-of-flight (TOF), without interleaving the FUS pulses and imaging acquisition. Decimation by 3–7 frames increases signal-to-noise ratio (SNR) by 15.09±7.03 dB. Benchmarking tests of CUDA-optimized code show increase in processing speed of 35- and 300-fold in comparison with MATLAB parallel processing GPU and CPU functions, respectively, and we can estimate displacement from steered push beams ±10 mm from the geometric focus. Preliminary validation of displacement imaging in humans shows that the same driving pressures led to variable nerve engagement, demonstrating important feedback to improve transducer coupling, FUS incident angle, and targeting. Regarding the use of our technique for neuromodulation, we found that FUS altered thermal perception of thermal pain by 0.9643 units of pain ratings in a single trial. Additionally, 5 $\mu \text{m}$ of nerve displacement was shown in on-target versus off-target sonications. The initial feasibility in healthy volunteers warrants further study for potential clinical translation of FUS for pain suppression.
A survey of rollback-recovery protocols in message-passing systems

This survey covers rollback-recovery techniques that do not require special language constructs. In the first part of the survey we classify rollback-recovery protocols into checkpoint-based and log-based. Checkpoint-based protocols rely solely on checkpointing for system state restoration. Checkpointing can be coordinated, uncoordinated, or communication-induced. Log-based protocols combine checkpointing with logging of nondeterministic events, encoded in tuples called determinants. Depending on how determinants are logged, log-based protocols can be pessimistic, optimistic, or causal. Throughout the survey, we highlight the research issues that are at the core of rollback-recovery and present the solutions that currently address them. We also compare the performance of different rollback-recovery protocols with respect to a series of desirable properties and discuss the issues that arise in the practical implementations of these protocols.
SRC-Family Kinases in Acute Myeloid Leukaemia and Mastocytosis

Protein tyrosine kinases have been recognized as important actors of cell transformation and cancer progression, since their discovery as products of viral oncogenes. SRC-family kinases (SFKs) play crucial roles in normal hematopoiesis. Not surprisingly, they are hyperactivated and are essential for membrane receptor downstream signaling in hematological malignancies such as acute myeloid leukemia (AML) and mastocytosis. The precise roles of SFKs are difficult to delineate due to the number of substrates, the functional redundancy among members, and the use of tools that are not selective. Yet, a large num ber of studies have accumulated evidence to support that SFKs are rational therapeutic targets in AML and mastocytosis. These two pathologies are regulated by two related receptor tyrosine kinases, which are well known in the field of hematology: FLT3 and KIT. FLT3 is one of the most frequently mutated genes in AML, while KIT oncogenic mutations occur in 80–90% of mastocytosis. Studies on oncogenic FLT3 and KIT signaling have shed light on specific roles for members of the SFK family. This review highlights the central roles of SFKs in AML and mastocytosis, and their interconnection with FLT3 and KIT oncoproteins.
EBNA-1 titer gradient in families with multiple sclerosis indicates a genetic contribution

Objective In multiplex MS families, we determined the humoral immune response to Epstein-Barr virus nuclear antigen 1 (EBNA-1)-specific immunoglobulin γ (IgG) titers in patients with MS, their healthy siblings, and biologically unrelated healthy spouses and investigated the role of specific genetic loci on the antiviral IgG titers. Methods IgG levels against EBNA-1 and varicella zoster virus (VZV) as control were measured. HLA-DRB1*1501 and HLA-A*02 tagging single-nucleotide polymorphisms (SNPs) were genotyped. We assessed the associations between these SNPs and antiviral IgG titers. Results OR for abundant EBNA-1 IgG was the highest in patients with MS and intermediate in their siblings compared with spouses. We confirmed that HLA-DRB1*1501 is associated with abundant EBNA-1 IgG. After stratification for HLA-DRB1*1501, the EBNA-1 IgG gradient was still significant in patients with MS and young siblings compared with spouses. HLA-A*02 was not explanatory for EBNA-1 IgG titer gradient. No associations for VZV IgG were found. Conclusions In families with MS, the EBNA-1 IgG gradient being the highest in patients with MS, intermediate in their siblings, and lowest in biologically unrelated spouses indicates a genetic contribution to EBNA-1 IgG levels that is only partially explained by HLA-DRB1*1501 carriership.
Acute Joint Blockage due to Abrasion-Related Dislocation of a Silastic Radial Head Prosthesis: A Histological Examination after 14 Years of Durability

The implantation of a radial head prosthesis can take place as a therapeutic option after radial head fracture. There are various implants for this purpose. Many studies and case reports about silastic radial head prosthesis implantation describe foreign body reactions with accompanying synovitis and poor functional results. A few studies have investigated the reason for the material failure and the accompanying synovitis. The case report presented shows an unusually long durability of an in situ 14-year silastic radial head prosthesis. 14 years after implantation, a previously full-time working and healthy patient presented himself with a dislocation of the silastic radial head prosthesis and atraumatic joint blockage of the right elbow triggered by a negligible movement. The prosthesis was removed surgically. We found a macroscopic foreign body reaction intraoperatively. In a histopathological examination, with hematoxylin and eosin staining (HE) in 40x and 100x magnification, we have seen an aseptic inflammatory response to foreign bodies with activated epithelial cells and multinucleated giant cells with intracytoplasmic foreign material. Due to these problems, the silastic radial head prosthesis is no longer used today. However, there are still patients with the implanted silastic radial head prosthesis, which should therefore be checked regularly. A metal prosthesis also does not seem to be an optimal alternative due to cartilage wear and loss of ROM. The choice of prosthesis material should be selected carefully and patient-specific in radial head prosthetics according of the results presented.
Metastatic Castration-Resistant Prostate Cancer with Neuroendocrine Transformation and BRCA 1 Germ-Line Mutation: A Case Report and Literature Review

Abstract A 63-year-old man with a significantly high prostate-specific antigen level was diagnosed via pathology to have advanced prostate adenocarcinoma due to multiple lung metastases. He was then treated with androgen deprivation therapy (ADT) comprising bicalutamide and goserelin. Only after 6 months of stable disease, the cancer progressed and the drug was changed to abiraterone; however, no significant therapeutic effect was observed and the disease was considered as castration-resistant prostate cancer. The histopathologic analysis of the biopsied metastatic lymph node confirmed small-cell neuroendocrine carcinoma, and genetic testing revealed BRCA1 germ-line mutation. The oral PARP inhibitor olaparib was used and achieved a partial tumor response over a period of 2.5 months. Meanwhile, palliative radiotherapy was performed for pain control in the sacrococcygeal region with complete symptom relief. The combination chemotherapy strategy of etoposide and cisplatin was used after the failure of olaparib and achieved pain alleviation in the left leg. The patient received one cycle of this chemotherapy strategy and eventually died of a rapid tumor progression, respiratory failure, and heart failure on April 27, 2019.
Effect of Shot Peening on Redistribution of Residual Stress Field in Friction Stir Welding of 2219 Aluminum Alloy

Welding is one of the essential stages in the manufacturing process of mechanical structures. Friction stir welding structure of aluminum alloy has been used as a primary supporting member in aerospace equipment. However, friction stir welding inevitably generates residual stress that promotes the initiation and propagation of cracks, threatening the performance of the welded structure. Shot peening can effectively change the distribution of residual stress and improve the fatigue properties of materials. In this paper, friction stir welding and shot peening are performed on 2219 aluminum alloy plates. The residual stress fields induced by friction stir welding and shot peening are measured by using the X-ray diffraction method and incremental center hole drilling method, and the distribution characteristics of residual stress fields are analyzed. The effect of the pellet diameters and pellet materials used in shot peening on the redistribution of welding residual stress field are investigated. The pellet diameter used in the experiment is in the range of 0.6–1.2 mm, and the pellet material includes glass, steel, and corundum. This study provides guidance for the application of shot peening in friction stir welding structure of 2219 aluminum alloy.