Miracle-dz/UniFAR-FTUs huggingface dataset:
Efficient Data Storage and Searching for Location Based Services using Quadtrees and H-ordering

—Data is always stored in secondary storage Devices due to its volume. When it is stored in secondary storage devices, it is required that the access time is as minimal as possible. Most of the queries issued for providing location based services, result in accessing nearest point. This paper provides an algorithm to store the data efficiently so that accessing time is reduced for answering such queries using a space filling curve called Hilbert Curves and quadtrees.
A Novel Method for Assisted- Indian Regional Navigation Satellite System

Indian Regional Navigation Satellite System (IRNSS) is a system of satellites developed by India to become independent nation in the navigation technology. Upon receiving the navigation data bits using the radio signals transmitted by the satellites, a user computes its own location. For any user, minimum of four such satellites are required to compute its location. To decode fresh navigation data bits, a receiver requires at least 40 to 50 seconds in an area where the signal strength of satellites are high. But in a location like deep forest, urban canyons, inside a building, the signal strength is very poor. In such a situation, the receiver either takes too long to decode the messages or it may not receive the signal at all. The penetrated signal is enough to compute the distance from the satellite but is insufficient to decode the navigation messages. This results in long position computation time or a complete outage. In the emergency services such as SOS or 911 calls, a quick and accurate location is needed. For pre-programmed way point navigation, initial location is necessary prior to the travel. A novel method is proposed to compute the position using GSM or CDMA mobile network as assistance link. By exploring the Secure User Plane Location (SUPL) extension, the assistance parameters can be made available to the required users. This type for assistance is new to IRNSS receivers and is called as Assisted Indian Navigation Satellite System (A-IRNSS). Upon quickly receiving the live navigation bits, a user can obtain quick position within 3-4 seconds. Extensive experimentation has been conducted on real time satellite data.
Effect of Tillage and Water Management on Aggregate Stability of a Gleyic Cambisols

The objective of this study was to determine the effect of tillage and water management on the physical stability of irrigated lowland rice field, in Kwalkwalawa, Sokoto State. The experiment was carried out in a farmer`s field, near the Usmanu Danfodiyo University Teaching and Research Farm, Kwalkwalawa, Sokoto State. The coordinates of the area were taken using global positioning system (GPS) model Garmin etrex 20.0, which shows that the area is located on (N13°05.963”E005°12.650” and at 252 m asl). The soils of the study area were classified as Aeric Endoaquepts at subgroup level in the USDA Soil Taxonomy System which correlated with Gleyic Cambisols in the World Reference Base. The treatments consisted of factorial combination of two tillage systems (conventional tillage (CT) and reduced tillage (RT), three irrigation water managements (Alternate one, two and three days irrigation intervals, which were carried out from one week after transplanting to hard dough stage) and three rice varieties (FARO 44, 60 and 61) all laid in a split-plot design and replicated three times. After harvest, disturbed soil samples were collected with the aid of soil auger, prepared and passed through 5 mm sieve for aggregate stability determination. Result reveals that a consistent trend in aggregate size fraction was observed between the two tillage systems in both years, were a significant decrease in values of aggregate fractions of both the CT and RT in 2019 compared to in 2018. Aggregate size fraction of 5-2 mm had a significantly high value of RT compared to CT, 2-0.25 mm fractions were at par (0.41) while a greater value of aggregate fractions for CT in both 0.25-0.005 mm and ˂0.005 mm Original Research Article Manasseh; IJPSS, 31(4): 1-8, 2019; Article no.IJPSS. 53482 2 were observed compared to RT. Alternate days to irrigation and sampling depths increase with a corresponding in all the aggregate size classes in the two years of this study. A significant difference in mean weight diameter (MWD) and geometric mean diameter (GMD) between the two tillage, water management and depth was noticed in both years of the trial where RT and alternate one day had high value while MWD and GMD increase with increasing depth.
Enhanced Hybrid Multipath Routing Protocol Using an Priority Acknowledgment Table (PAT)

—Route discovery and route maintenance concerns a main issue in MANET. To address this problem we propose an efficient hybrid routing technique using Priority Acknowledgement Table. Our proposed work uses both On-demand and Table driven routing protocols for continuous route discovery between source and destination in multipath and multicast environment. Here we use a Priority Acknowledgement Table technique to find the shortest alternative path. In initial stage a single route is discovered using On-Demand routing protocol. From that route each node involves in continuous discovery of another shortest path to reach destination. At that time if a node finds more than two alternate paths, then it is declared as DPN and a temporary PAT is constructed from which again a new route is discovered to reach the destination. In our proposed work if route failure occurs, route rediscovery starts from DPN instead of from original source node by which efficiency is increased.
Comparative pharmacokinetics of PLGA & PCL based long acting injectable (LAI) risperidone microsphere formulations

The objective of the study was to compare and evaluate the pharmacokinetics of biodegradable PLGA & PCL microspheres with Risperidal Consta TM for achieving the sustained delivery of Risperidone in the schizophrenia therapy. Five microsphere formulations of risperidone were prepared by using two PLGA copolymers (50:50 and 75:25) and PCL (PCL-45000 and PCL-80000) polymer. All the five novel microsphere formulations (PLGA1-4 & PCL) and Risperidal Consta TM was administered to male Sprague Dawley rats through subcutaneous route at different dose. PLGA & PCL formulations achieved higher exposure than Risperidal consta TM ie among PLGA based formulations ranked in the following order (PLGA1(1.6x) > PLGA2 (1.5x) > PLGA3 (1.2x) > PLGA4 (0.9x)) whereas PCL formulation demonstrated 1.3x higher exposure than Risperidal Consta. Simulations of multiple dosing at weekly or 15-day regimen to predict the in vivo profile of risperidone following subcutaneous administration of PLGA1-4 and PCL microspheres formulations and compared with marketed Risperidal Consta TM revealed pulsatile behavior for all formulations with steady state being achieved by the second dose. Based on simulations it was observed that PLGA & PCL based formulations can be utilised to provide weekly and once in 15 day dosing regimen which could be an effective approach for sustained delivery of this molecule and a possible alternative to the currently available combination therapy. Therefore based on our study we conclude that development of novel microsphere based formulation by combining the PLGA & PCL systems to prepare long acting dosage forms with atypical antipsychotics will ensure patient compliance, reduce side effects, and improve the quality of life for patients who suffer from schizophrenia.
Comparative study of image retrieval methods for mining user queries

— Image retrieval is most important concept nowadays. When user provides a query in the form of keywords or in the form of image then system provides similar kind of images according to user queries. When database is very large then to deal with such database is hard process. Hence Annotation Based Image Retrieval is the technique is used to retrieve the similar images according to the query provided by user. Query may be in the form of image known as Content Based Image Retrieval or may be in the form of text. Content based image retrieval process is having certain limitations in terms of retrieval accuracy and time. Hence Annotation Based Image Retrieval technique is used to retrieve the images from large database. Markov chain method with relevance feedback method is used to speed up the performance of Image retrieval method.
Comparison of Extremely Halophilic Archaea Isolated from Three Salt Lakes in China

There’re many kinds of extremely halophilic archaea living in salt lakes all over the world and the ecological environment of lakes can affect their archaeal species. To illustrate the relationships between archaeal species and salt lake environment, we isolated and cultured 25 extremely halophilic archaeal strains from three salt lakes in China (Gou Salt Lake, Huama Salt Lake and Yuncheng Salt Lake). According to the 16S rRNA gene sequence analysis and the construction of Neighbor-Joining phylogenetic trees, the isolates were closely related to each other. The most dominant archaea was genus halorubrum (88.0%), followed by genus haloarcula (8.0%) and a small amount of genus halovivax (4.0%). Yuncheng salt lake (YC) had the most abundant number of species. Through the study of the basic information of the three sampling sites, we considered the species of extremely halophilic archaea were related to their living natural conditions of brine. Warm weather and high mineralization degree are likely to be functional components to enrich the species diversity.
Security Issues in SaaS Delivery Model of Cloud Computing

— SaaS (Software as a service) is one of the main service provided by cloud computing it has a feature of multi tenancy that virtually provides the services on one by one basis but physically all user utilize the services at same time. It has received considerable attention in past few years and an increasing number of countries show their interest in the promotion of SaaS market. Although it has received significant attention but security issue is one of the major inhibitor in decreasing the growth of SaaS. Many organizations may still be hesitant to introduce SaaS mainly because of the trust and security concerns, they may observe more risks than benefits in introducing this service. In this study an attempt is made to discuss the security issues and their existing solutions in SaaS delivery model of cloud computing.
In vitro Propagation of the Endangered Medicinal Plant Hyoscyamus muticus L. (Egyptian Henbane)

An efficient plant regeneration protocol has been developed from in vitro germinating seeds of Hyoscyamus muticus L. (Egyptian henbane), a medicinally important plant in the family Solanaceae. Newly growing stem segment were established on MS media fortified with various concentrations of 6benzyladenine (BA,1.03.0 mg/l) and kinetin (KN,1.0-3.0 mg/l) alone or in combination with 2iP (0.5 mg/l). The maximum mean number of shoots per explant (8.20) with average length (1.37) cm was achieved with medium containing 1.0 mg/l KN alone. The highest number of shoots (8.200) with average length (1.374cm) was obtained by subculture on MS medium supplemented with 1.0 mg/l KN after four weeks and the number of shoots formed per explant increase gradually by subculturing on the same media up to 12.467 of shoot formed per explant with average length 2.298 cm in the fourth subculture. Rooting of shoots was achieved on MS medium supplemented with 1.0 mg/1 indole butyric acid (IBA). Well-developed plantlets which are transferred to plastic pots containing soil and peat moss (1:1) showed 75-90% survival and were then transplanted in glasshouse and normally transferred to environmental conditions. The described method can be successfully employed for large-scale multiplication and conservation of H.muticus (an endangered medicinal plant).
Application of Dimensionality Reduction techniques in Real time Dataset

– Data pre-processing in data mining refers to transforming the raw data into understandable format for further analysis. The real time data is incomplete, robust and unorganised which should be cleaned and transformed to make it efficient for pre-processing. In this paper, we have discussed about three dimensionality reduction techniques namely Principal Component Analysis (PCA), Singular Value decomposition and Learning Vector Quantization applied to solar irradiance dataset. The dataset consists of temperature, solar irradiance, and humidity data for 25 years for selected eight south Indian cities. The dimensionality reduction was done by applying the above mentioned three algorithms and their efficiency was evaluated, to find the best suiting algorithm to apply for the dataset.
Antimicrobial activities of Lepidium sativum : Medicinal plant used in folklore remedies in India

Antimicrobial properities of seed extracts of Lepidium sativum were investigated against Escherichia coli, Staphylococcus aureus, Streptococcus mutans, Candida albicans and Pseudomonas aeruginosa using agar well diffusion assay. Methanol extract exhibited the highest zone of inhibition against Streptococcus mutans (31 mm) followed by Pseudomonas aeruginosa (17mm), Candida albicans (15.5 mm), Staphylococcus aureus (15mm) and Escherichia coli (12.5 mm). The ethanol extract showed greater zone of inhibition against P. aeruginosa (18 mm). Hexane extract exhibited the greatest zone of inhibition against C. albicans (16 mm). In vitro studies of L. sativum ethanolic seeds extracts showed its effectiveness against gram positive and negative bacteria and ineffectiveness against the fungal isolate. Bioactive substances from this plant can therefore be employed in the formulation of antimicrobial agents for the treatment of various bacterial and fungal infections including gonorrhea, pneumonia, eye infections and mycotic infections.
Synthesis, characterization and kinetics of thermal decomposition of 2'-amino-1-benzyl-6'-(1H-indol-3-yl)-2-oxospiro[indoline-3,4'-pyran]- 3',5'-dicarbonitrile under non isothermal condition in nitrogen atmosphere

A spirooxindole compound, namely 2’-amino-1benzyl-6’-(1H-indol-3yl)-2-oxospiro[indoline-3,4’-pyran]3’,5’-dicarbonitirile [ABzIOIPD] was synthesized and characterized by microanalysis, FT-IR, mass specta and NMR (H and C) techniques. The thermal decomposition of the compound was studied by thermogravimetric analysis under dynamic nitrogen atmosphere at different heating rates of 10,15,20 and 30 K min. The kinetic parameters were calculated using model fitting (Coats– Redfern, CR) and model–free methods (Friedman, Kissinger–Akahira–Sunose, KAS and Flynn–Wall-Ozawa, FWO). The decomposition process of ABzIOIPD followed a single step mechanism as evidenced from the data. Existence of compensation effect is noticed for the decomposition of ABzIOIPD. Invariant kinetic parameters are consistent with the average values obtained by Friedman and KAS inconversional methods.
Antioxidant Potential of Paavu Chooranam Prescribed to Cure Breast Cancer by the Cheruthikonam Traditional Siddha Medicinal Practitioner of Kanyakumari District, India

Paavu Chooranam is a Siddha polyherbal formulation comprised of 14 traditionally used herbs explore for the treatment of cancer. The present investigation was mainly focused on the antioxidation activities since, there is no information regarding pharmaceutical activities of antioxidants Hydroxyl radical scavenging, DPPH, Nitric oxide radical scavenging, Hydrogen per oxide radical scavenging and Reducing power activity. The unexplored area of Paavu Chooranam towards their antioxidation effect in aqueous, silver nitrate and ethanol extracts indicated promising antioxidant activities of crude extract.
FORMULATION AND EVALUATION OF ORODISPERSIBLE TABLETS OF BACLOFEN

The aim of this investigation was to prepare orodispersible tablets of baclofen using various concentrations of superdisintegrant agents like Ac-Di-Sol, crospovidone, sodium starch glycolate by direct compression method. Nine formulations having superdisintegrants at different concentration levels were prepared. These tablets were evaluated for drug content, weight variation, friability, hardness, wetting time and invitro disintegration time. Among the formulations tablets of batch F3 containing Ac-Di-Sol showed superior organoleptic properties along with excellent in-vitro disintegration time and drug release as compere to other formulations. It was concluded that superdisintegrants addition technique is a usuful method for preparing orodispersible tablets by direct compression method.
Exploring the Relationship between Organizational Culture, Job Satisfaction and Organizational Citizenship Behavior

This study examined the interaction between organizational culture, organizational citizenship behaviors and job satisfaction. While organizational culture plays an important role in affecting performance, other variables mediate and moderate the relationship. This study was based on a sample of 127 Egyptian participants undertaking an MBA course. Results showed positive significant correlations between four types of organizational culture, job satisfaction and citizenship behavior individually. Job satisfaction mediated the relationship between culture and citizenship behavior. However, the mediation effect was weak. Further discussion, implications and research limitations are provided.
Survey on Analysis of Various Techniques for Multimedia Data Mining

– Data mining is an art which is used and applied discipline for grown out the various statistical pattern recognition,learning macheine,and artificial intelligence which is combined with business decision making to optimize and enhance it.Initially the techniques of Data mining have been applied to the already structured data from the database. The highly usage of computers makes data mining affordable for small companies but on the other hand the invention of cheap massive memory and digital recording electronic devices allowed the misuse of the private sector such as corporate,governmental and private documents.for ex-e-mail message from customer,recording from telephonic conversation between customers and operators.to handle such condition multimedia data mining is available.The aim of multimedia data mining is to process media data alone or combination with other data for finding patterns usefull for business.
DEVELOPMENT AND VALIDATION OF SECOND ORDER DERIVATIVE SPECTROPHOTOMETRIC METHOD FOR SIMULTANEOUS ESTIMATION OF ATENOLOL AND NIFEDIPINE IN COMBINED DOSAGE FORM

A simple, precise, accurate and reproducible spectrophotometric method has been developed for Simultaneous estimation of Atenolol and Nifedipine by employing second order UV derivative Spectrophotometric method in Water: ACN (60:40). The Second order derivative absorption at 245.63 nm (zero cross point of Nifedipine) was used for quantification of Atenolol and 218.7 nm (zero cross point of Atenolol) for quantification of Nifedipine. The linearity was established over the concentration range of 50-150 μg/ml and 20-60 μg/ml for Atenolol and Nifedipine with correlation coefficient (r 2 ) of 0.999 and 0.998 respectively. Interday and intraday studies showed repeatability of the method. The mean % recoveries were found to be in the range of 99.25% – 101.15% and 98.56% – 101.85% for Atenolol and Nifedipine, respectively. The method is successfully applied to pharmaceutical formulation, with no interference from excipients as indicated by the recovery study. The proposed method has been validated as per ICH guideline and successfully applied to the simultaneous estimation of Atenolol (ATN) and Nifedipine (NIF) in their combined Tablet dosage form. So it was recommended for routine analysis. The use of 60% Distilled water as a solvent makes method Cost effective and economical. INTRODUCTION: Atenolol is chemically 2-(4{2-hydroxy-3-[(1-methylethyl) amino] propoxy} phenyl)acetamide shown in Figure 1A. It acts by competing with sympathomimetic neurotransmitters such as catecholamines for binding at β1-adrenergic receptors in the heart and vascular smooth muscle, inhibiting sympathetic stimulation. This results in a reduction in resting heart rate, cardiac output, systolic and diastolic blood pressure, and reflex orthostatic hypotension. QUICK RESPONSE CODE DOI: 10.13040/IJPSR.0975-8232.4(10). 3884-88 Article can be accessed online on: www.ijpsr. com DOI link: http://dx.doi. org/10.13040/IJPSR.0975-8232.4(10). 3884-88 Nifedipine (3, 5-dimethyl 2, 6-dimethyl-4-(2nitrophenyl)-1, 4-dihydropyridine-3, 5 dicarbo xylate) shown in Figure 1B. It acts by blocking the Ca ++ channel. It is used in the treatment of Variant (Prinzmetal) Angina, Hypertension and Left ventricular dysfunction. The mixture of Atenolol and Nifedipine is commonly used for hypertension. A Tablet Dosage form containing (ATN-50 mg & NIF-20 mg) is commercially available. Literature survey revealed the most recent methods for determination of Atenolol and Nifedipine like liquid chromatographic, electrochemical and spectrophotometric techniques. Different Spectrophotometric methods were available in literature survey. However, no 2 nd order derivative method in this solvent ratio had been reported till the date which makes its cost effective for the determination of this combination.
THE INTERNATIONAL JOURNAL OF SCIENCE & TECHNOLEDGE Efficient Bootsrapping and Query Adaptive Ranking for Image Search

: Scalable image search based on visual similarity has been an active topic of research in recent years. State-of-the-art solutions often use hashing methods to embed high-dimensional image features into Hamming space, where search can be performed in real-time based on Hamming distance of compact hash codes. Unlike traditional metrics (e.g., Euclidean) that offer continuous distances, the Hamming distances are discrete integer values. As a consequence, there are often a large number of images sharing equal Hamming distances to a query, which largely hurts search results where fine-grained ranking is very important.I introduces an approach that enables query-adaptive ranking of the returned images with equal Hamming distances to the queries. This is achieved by firstly offline learning bitwise weights of the hash codes for a diverse set of predefined semantic concept classes. We formulate the weight learning process as a quadratic programming problem that minimizes intra-class distance while preserving inter-class relationship captured by original raw image features. Query-adaptive weights are then computed online by evaluating the proximity between a query and the semantic concept classes.With the query-adaptive bitwise weights, returned images can be easily ordered by weighted Hamming distance at a finer-grained hash code level rather than the original Hamming distance level. Experiments on a Flickr image dataset show clear improvements from our proposed approach.
BIOAVAILABILITY AND DISSOLUTION ENHANCEMENT OF GLYBURIDE NANOSUSPENSION

Objective: The main objective was to develop nanosuspension of glyburide (GLY) by quasi emulsification solvent diffusion method and to enhance dissolution and bioavailability characteristics of the drug GLY, an antidiabetic drug which belongs to Biopharmaceutical Classification System-II category. Results: From these studies, it was confirmed that drugs and excipients chosen were compatible with each other. GLY-8 was the best formulation with a particle size of 85–96 nm with 168.7°C melting point, freely soluble in phosphate buffer pH 7.4, 93.53% drug entrapment, and 90.26±1 mV of zeta potential. This formulation shows percentage drug release of 99.85% in 24 h. In vivo pharmacokinetic study for optimized formulation (GLY -8) suggested that there was no reaction with the rat plasma. From the results, it was shown that Cmax and Tmax were found to be 0.604±0.03 μg/ml and 2±1.01 h, respectively. The values of t1/2 (h), area under the curve (AUC) (0-t), and AUC (0-∞) were found to be 10.04 h, 2.562±0.41 μg. h/ml, and 2.147±0.45 μg. h/ml, respectively. Conclusion: Based on the results obtained, oral administration of nanosuspension could not only provide the better absorption of poorly water soluble drugs but may also reduce toxicity and provide a new tool in drug delivery system.