Miracle-dz/UniFAR-FTUs huggingface dataset:
Examining the development process of a semantic hub in an enterprise environment

Department of Information Science and Media Studies Examining the development process of a semantic hub in an enterprise environment by John Fredrik Asphaug In the resent years there has been developed a couple of semantic hubs in the Norwegian oil and gas industry, and now EPIM is in the process of developing a semantic hub called the LogisticHub. It will be a track and trace system for cargo and containers in the offshore supply chain, utilising Semantic Web technology to share and communicate between the different organisations. The semantic hub as an information system is considered to be a new type of information system, that could benefit from a closer look at its development process. In this thesis I will look at the development process of the LogisticHub, in an attempt to discover the differences in developing a semantic hub compared to the development of other information systems.
NUMERICAL MODELLING OF COUPLED DRAWDOWN AND WAKE

Pacific International Engineering has developed the Ship-Generated Hydrodynamics (SGH) computer model in order to predict the effects of deep-draft vessel traffic. The SGH model is comprised of two dynamically-coupled sub-models, one for the wake and one for the drawdown, which calculate vessel-generated water surface fluctuations, current velocities and wake transformation. The model is constructed to permit the use of complex channel geometry and bathymetry, realistic ship hull shapes and variable sailing lines, and employs an auto-calibration technique to ensure accurate wake generation. This advanced computer model has been used successfully and cost-effectively on a number of projects in Canada and the US. This paper describes the governing equations and structure of the SGH model, and its application to a problem on the St. Lawrence River near Sorel, Quebec.
Electromagnetic actuators for controlling flexible cantilever beams

Electromagnetic actuators are very important for scientific and industrial applications. Their use may vary within a wide range of possibilities due to their most important feature: the ability to apply known and controllable forces to elements or structures without contact. In this article, an application within this range is analyzed: a proportional‐integral‐derivative (PID) controller is used with a pair of actuators to control the dynamic forced response of a flexible cantilever metallic beam and to keep it at a given reference position. In order to achieve this objective, both the actuators and the controller need to be adjusted. For the actuators, the main parameters evaluated consider mounting particularities, such as the differential assembly and the influence of the air‐gap distance over the magnetic flux density and the magnetic force provided. Next, a brief review of PID controllers is presented, highlighting 5 tuning methods, and their effects on relevant parameters of the electromagnetic system (such as the cutoff frequency). Finally, results focus on the comparative efficiency of the PID tuning methods to reduce the vibration amplitude of the beam bending modes. The results show that the Ziegler–Nichols modified for some‐overshoot and no‐overshoot methods are the best choices.
Microelectrode array systems for their use in single nanowire-based gas sensor platforms

Abstract Microelectrode array systems for their use in single-nanowire-based gas sensor platforms are developed. The topology of the system is designed with the aim of determining the optimal conditions and the factors involved in the selective integration of gas sensitive semiconducting metal oxide nanowires via dielectrophoresis method. Thus various electrode geometries with electrode gaps between 2 and 10 μm and electrode tip-end shapes are investigated employing tungsten oxide nanowires synthetized via aerosol-assisted chemical vapor deposition. Results obtained from SEM, optical microscopy and electrical tests demonstrate that the integration and electrical contact of single nanowires across the electrodes is achieved in the systems with electrode gaps below 3 μm. These results are discussed and further improvements in the design of these systems are suggested.
Establishing HR practices-employee performance relationship through literature survey

The success of any organization hinges on human resource of such organization.Human resource has the skills, knowledge and competencies required for the execution of organizational strategy and planning.Human resource is a crucial to the enhancement of sustainable competitive advantages and enhanced firm performance.Substantial numbers of HRM research have indicated positive effect of HR practices on employee performance.Yet, some other studies indicate the otherwise.Thus, the findings of the extant research are seemingly inconclusive.To address this issue, this paper, via an across-the-board literature survey, establish that HR practices involving recruitment and selection, training and development, compensation, performance appraisal, and succession planning impact employee performance. It can be discerned that the research findings that deny or cast doubt on the HRM-Performance nexus could not hold water, given the fact that there have been an overwhelming bulk of empirical studies that establish the link between HRM and performance.Hence, this research further proposes the five HR practices to be the determinant of employee performance. However, the proposed model can be empirically solidified further via collection and analysis of relevant data.
Factors influencing crop diversification as a tool to twofold farmers’ earnings in Uttarakhand

Crop diversification is an important strategy for overall agriculture development in the country. The present study was an attempt to identify the factors affecting crop diversification in Uttarakhand state of India. The present study is based on primary data. Multistage stratified random sampling technique was followed to select 45 farmers from hill region and 30 farmers from plain region. Multiple linear regression was used to examine the factor affecting crop diversification. The major factors responsible for the change in crop diversification were fertilizer consumption, gross irrigated area, road length, mechanization and certified seeds, at districts, divisions and state level. In case of farm households age of household head, size of farm households, distance to market, off-farm/non-farm income and fertilizer which effects the crop diversification. The creation of basic infrastructural facilities is an essential prerequisite for crop diversification and fostering the process of agricultural development.
Robotic-assisted Versus Open Technique for Living Donor Kidney Transplantation: A Comparison Using Propensity Score Matching for Intention to Treat

Background. Living donor robotic-assisted kidney transplantation (RAKT) is an alternative to open kidney transplantation (OKT), but experience with this technique is limited in the United States. Methods. A retrospective review of living donor kidney transplants performed between 2016 and 2018 compared RAKT with OKT with regard to recipient, donor, and perioperative parameters. A 1:1 propensity score matching was performed on recipient/donor age, sex, body mass index, race, preoperative dialysis, and calculated panel reactive antibodies. Results. Outcomes of patient survival, graft survival, and postoperative complications were assessed for 139 transplants (47 RAKT and 92 OKT). Propensity score analysis (47:47) showed that RAKT recipients had longer warm ischemic times (49 versus 40 min; P < 0.001) and less blood loss (100 versus 150 mL; P = 0.005). Operative time and length of stay were similar between groups. Postoperative serum creatinine was similar during a 2-y follow-up. Post hoc analysis excluding 4 open conversions showed lower operative time with RAKT (297 versus 320 min; P = 0.04) and lower 30-d (4.7% versus 23.4%; P = 0.02) and 90-d (7% versus 27.7%; P = 0.01) Clavien-Dindo grade ≥3 complications. Conclusions. Our findings suggest that RAKT is a safe alternative to OKT.
Green Revenues for Greener Asia

Asian countries have been facing various environmental problems, ranging from air and water pollution to climate change. At the same time, many people seek higher income and further economic development, which requires more government revenue. This paper introduces carbon pricing, environmental tax, and emissions trading schemes, all schemes that can help achieve the two objectives: environmental conservation and revenue raising. The paper reviews experiences from the implementation of these policy instruments from the perspective of raising revenue and the effectiveness in environmental conservation with focus on Asia. Specifically, the experiences in India, Japan, the Republic of Korea, the People’s Republic of China, and Singapore show that governments can raise revenue while reducing emissions. We conclude our paper with policy implications.
Bioengineering Strategies to Create 3D Cardiac Constructs from Human Induced Pluripotent Stem Cells

Human induced pluripotent stem cells (hiPSCs) can be used to generate various cell types in the human body. Hence, hiPSC-derived cardiomyocytes (hiPSC-CMs) represent a significant cell source for disease modeling, drug testing, and regenerative medicine. The immaturity of hiPSC-CMs in two-dimensional (2D) culture limit their applications. Cardiac tissue engineering provides a new promise for both basic and clinical research. Advanced bioengineered cardiac in vitro models can create contractile structures that serve as exquisite in vitro heart microtissues for drug testing and disease modeling, thereby promoting the identification of better treatments for cardiovascular disorders. In this review, we will introduce recent advances of bioengineering technologies to produce in vitro cardiac tissues derived from hiPSCs.
BIM in the construction process – selected problems at the stage of implementation in Polish road engineering

: The digitalisation of the construction process is a phenomenon that has been signiﬁcantly accelerated in recent years. BIM (Building Information Modeling) technology is becoming increasingly popular with designers, contractors and investors and is being used, mainly in relation to buildings. In communication objects, the application of BIM is much more diﬃcult, as conﬁrmed by the shifting schedules during implementation trials in road design. And yet, BIM is not only about the design or execution of construction works, it is worth taking advantage of the new possibilities especially at the stage of using the facility. BIM in transportation infrastructure is already used in other countries, mainly in Scandinavia, where work on its implementation began at the beginning of this century. The preparation of appropriate procedures and standards, adjusted to national realities, requires gathering experience on pilot investments. The paper presents an analysis of the necessary initial data which will make it possible to apply BIM in the Polish road construction industry. Moreover, the main risks occurring at various stages of the construction process are presented. The aim of the article is to indicate the necessary actions that will allow the advantages of BIM technology to be used more fully in road investments. The implementation of BIM in Polish road construction is not a distant future but rather "tomorrow", so it is worth knowing the limitations and preparing for the upcoming changes.
Absolute Quantification of Nav1.5 Expression by Targeted Mass Spectrometry

Nav1.5 is the pore forming α-subunit of the cardiac voltage-gated sodium channel that initiates cardiac action potential and regulates the human heartbeat. A normal level of Nav1.5 is crucial to cardiac function and health. Over- or under-expression of Nav1.5 can cause various cardiac diseases ranging from short PR intervals to Brugada syndromes. An assay that can directly quantify the protein amount in biological samples would be a priori to accurately diagnose and treat Nav1.5-associated cardiac diseases. Due to its large size (>200 KD), multipass transmembrane domains (24 transmembrane passes), and heavy modifications, Nav1.5 poses special quantitation challenges. To date, only the relative quantities of this protein have been measured in biological samples. Here, we describe the first targeted and mass spectrometry (MS)-based quantitative assay that can provide the copy numbers of Nav1.5 in cells with a well-defined lower limit of quantification (LLOQ) and precision. Applying the developed assay, we successfully quantified transiently expressed Nav1.5 in as few as 1.5 million Chinese hamster ovary (CHO) cells. The obtained quantity was 3 ± 2 fmol on the column and 3 ± 2 × 104 copies/cell. To our knowledge, this is the first absolute quantity of Nav1.5 measured in a biological sample.
Evaluation of a colourimetric method for the measurement of oxidation in
butter

Butter is an emulsion of water in oil containing approximately 25% unsaturated fat. It is used in various types of cooking because of its delectable flavour. However, oxygen absorption by the unsaturated fatty acids alters its quality. Therefore, oxidation measurement is essential for the quality evaluation of butter. Although titrimetric analysis is mainly used for oxidation measurement in butter, it needs a large quantity of samples and reagents, and the results lack reproducibility. In this study, the colourimetric method was evaluated to measure oxidation levels in butter. A comparative analysis of the standard titrimetric methods and the colourimetric method revealed an increase in the oxidation levels with an increase in time. The findings demonstrated a positive correlation between the titrimetric and colourimetric methods. Furthermore, the measurement accuracy of the colourimetric method was less than 10% (1.7–9.5%) on all examination days. Overall, these findings suggest the efficiency of the colourimetric method to measure oxidation in butter with increased accuracy.
The Nurr1 activator 1,1-bis(3'-indolyl)-1-( p -chlorophenyl)methane blocks inflammatory gene expression in BV-2 microglial cells by inhibiting NF-κ

NR4A family orphan nuclear receptors are an important class of transcription factors for development and homeostasis of dopaminergic neurons that also inhibit expression of inflammatory genes in glial cells. The identification of NR4A2 (Nurr1) as a suppressor of NF-κ B-related neuroinflammatory genes in microglia and astrocytes suggests that this receptor could be a target for pharmacological intervention in neurological disease but compounds that promote this activity are lacking. Selected diindolylmethane analogs (C-DIMs) have been shown to activate or inactivate nuclear receptors, including Nurr1, in cancer cells and also suppress astrocyte inflammatory signaling in vitro . Based upon these data, we postulated that 1,1-bis(3’-indolyl)-1-(p-chlorophenyl)methane (C-DIM12) suppresses inflammatory signaling in microglia by a Nurr1-dependent mechanism. C-DIM12 inhibited LPS-induced expression of NF-κ B-regulated genes in BV-2 microglia including Nos2 , Il-6 , and Ccl2, and the effects were attenuated by Nurr1-RNA interference. Additionally, C-DIM12 decreased NF-κ B activation in NF-κ B-GFP reporter cells and enhanced nuclear translocation of Nurr1 primary microglia. Chromatin immunoprecipitation assays indicated that C-DIM12 decreased LPS-induced p65 binding to the Nos2 promoter and concurrently enhanced binding of Nurr1 to the p65-binding site. Assessment of corepressor recruitment to the p65 binding site of the Nos2 promoter revealed that C-DIM12 stabilizes the nuclear corepressor complexes CoREST and NCoR2. Collectively, these data identify C-DIM12 as a modulator of Nurr1 activity that results in inhibition of NF-κ B-dependent gene expression in glial cells by stabilizing nuclear corepressor proteins that reduces binding of p65 to inflammatory gene promoters. gene transcription microglial dopamine We postulated that C-DIM12 inhibits inflammatory signaling in BV-2 microglia by enhancing Nurr1-dependent transrepression of NF-κ gene We present data here that C-DIM12 is able to suppress pro-inflammatory gene transcription in BV-2 microglia after stimulation with LPS. Additionally, investigated whether the transcriptional inhibitory activity of C-DIM12 Nurr1 and how modulation of Nurr1 by C-DIM12 the activity of nuclear corepressor proteins at p65 DNA binding
A study on the determinants of customer intention to the use of online banking

Numerous Vietnamese banks have launched online banking services to offer improved service to existing customers and attract new ones. However, online banking new to most people in Vietnam, and rates of adoption of online banking. This study focuses on this issue and attempts to identify the determinants of customer intention to use online banking. A research framework based on the DeLone and McLean Information System Success (D and M IS) model for assessing website quality and the literature on brand credibility was developed to identify the factors that can affect customer intention to use online banking. This study uses customers of the financial industry in Vietnam as subjects and collects 164 valid questionnaires. Partial Least Squares (PLS) method is applied in the investigation. The analytical results indicate that brand credibility can affect customer intention to use online banking.
APPROXIMATION OF MULTIPHASE MEAN CURVATURE FLOWS WITH NON HARMONICALLY ADDITIVE MOBILITIES

A BSTRACT . This paper concerns the robust approximation of multi-phase mean curvature ﬂow by phase ﬁelds even when the phase mobility are highly contrasted. Recent work suggested that harmonically additive mobilities could be incorporated in the metric of the associated gradient ﬂow. We generalize this approach to arbitrary mobilities, by splitting them as a sum of a harmonically additive mobilities. We establish the consistency of the resulting method, by analyzing the sharp interface limit of the ﬂow : a formal expansion of the phase ﬁeld shows that the method is of order 2. Finally, we present some numerical experiments in dimensions 2 and 3 that illustrate the interest of our method, in particular in the modeling of ﬂows in which some of the phases have 0 mobility.
Validation of an electrochemiluminescent-based assay for α-Synuclein detection in cerebrospinal fluid

Background: Abnormal α-synuclein aggregation and deposition is the pathological hallmark of Parkinson’s disease and dementia with Lewy bodies, but is also found in Alzheimer’s disease. Therefore, there is a gaining interest in α-Synuclein in cerebrospinal fluid (CSF) as potential biomarker for these neurodegenerative diseases. Objectives: To broaden the available choices of α-Synuclein measurement in CSF, we developed and validated a new, independent assay for detecting total α-Synuclein. Methods: This novel ELISA uses commercially available antibodies and is based on electrochemiluminescence technology. The assay protocol is straightforward with short and simple incubation steps and requires only small amounts of CSF. We validated this assay for precision, parallelism, dilution linearity, specificity, and spike recovery. We further compared it to the newly validated α-Synuclein assay from BioLegend by analyzing a set of 50 CSF samples with both assays. Results: The new assay quantifies α-Synuclein in CSF with a lower limit of detection of 0.0363 ng/ml and shows no cross-reactivity with human  - and  -Synuclein. Results of dilution linearity, parallelism, spike recovery and precision classify this assay as well suited for α-Synuclein detection in human CSF samples. Conclusion: We present a novel assay based on freely available components to quantify total α-Synuclein in CSF as an additional method for α-Synuclein as a biomarker in neurodegenerative diseases. The assay convinces with its simple and convenient protocol paired with
Growth of Methylobacterium organophilum in Methanol for the Simultaneous Production of Single-Cell Protein and Metabolites of Interest

SUMMARY Research background This study aims to monitor the growth of the methylotrophic bacteria Methylobacterium organophilum in a culture medium with methanol as a carbon source and to verify the production of unicellular proteins and other biomolecules, such as carotenoids, exopolysaccharides and polyhydroxyalkanoates, making them more attractive as animal feed. Experimental approach Bacterial growth was studied in shake flasks using different carbon/nitrogen (C:N) ratios to determine their best ratio for achieving the highest volumetric productivity of cells and substrate consumption rate. This optimal parameter was further used in a fed-batch operating bioreactor system to define the kinetic profile of cell growth. Methanol consumption was measured by HPLC analysis and the extracted pigments were analyzed by liquid chromatography/mass spectrometry. Chemical composition and rheological properties of the produced exopolysaccharides were also determined. Results and conclusions The best experimental parameters were verified using an initial methanol concentration of 7 g/L in the culture medium. The same initial substrate concentration was used in the fed-batch operation and after 60 h of cultivation 5 g/L of biomass were obtained. The accumulation of carotenoids associated with cell growth was monitored, reaching a concentration of 1.6 mg/L at the end of the process. These pigments were then analyzed and characterized as a set of xanthophylls (oxidized carotenoids). In addition, two other product types were identified during the fed-batch operation: exopolysaccharides, which reached a concentration of 8.9 g/L at the end of the cultivation, and an intracellular granular structure that was detected by transmission electron microscopy (TEM), suggesting the accumulation of polyhydroxyalkanoate (PHA), most likely polyhydroxybutyrate. Novelty and scientific contribution Methylobacterium organophilum demonstrated a unique ability to produce compounds of commercial interest. The distinct metabolic diversity of this bacterium makes room for its use in biorefineries.
Development of algorithm for Newtonian compressible fluid flow based on finite element method

In this article, we present the numerical investigation for compressible Newtonian flow in two dimensional axisymmetric channel. Galerkin finite element method is applied to accommodate compressible and incompressible flows. A continuity equation and time-dependent conservation of momentum equations are used to describe the motion of the fluid, which are maintained in the cylindrical coordinate system (axisymmetric). To meet the method analysis, Poiseuille flow along a circular channel under an isothermal state is used as a simple test problem. This test is conducted by taking a circular section of the pipe. Comparision between compressible and incompressible results in terms of convergence has been conducted for axial velocity and pressure. Findings reveal that, convergence-rates of velocity and pressure is faster an incompressible case compared to compressible. In addition, the level of velocity convergence is higher than pressure for both compressible and incompressible. Moreover, the low level of Mach number demonstrates that piecewise-constant density interpolation is equitable to linear density interpolation
TELKOMNIKA Telecommunication Computing Electronics and Control

Received Oct 15, 2020 Revised Jan 27, 2022 Accepted Feb 04, 2022 This paper aim to provide a basic fundamental knowledge for researchers on underwater remotely operated vehicle (ROV) system and current trend of ROV controller. The vehicle is used for exploration, investigation or inspection of underwater environment as a replacement of human due to human limitation. It can dive deeper than human and can be manoeuvred into hazard environment. In this paper, the basic development and classification of ROV is discussed. The modelling of ROV, manoeuvrability and controller designed by researchers since 1990 also being discussed. It is expected that this paper will help readers in doing research on the controller of ROV.