Miracle-dz/UniFAR-FTUs huggingface dataset:
A novel fast glitchless 7-3 counter with a new structure

This paper discusses about the design of a novel fast 7-3 counter for CMOS low power, high speed multiplier. In order to reduce delay and increase the speed, some changes have been made in the structure of the counters. Also the occupied area by the counter is decreased because of the less number of transistors. The delay of the proposed structure is 185ps which is simulated by HSPICE using TSMC 0. 18μm CMOS technology.
Error rate performance for STBC in free-space optical communications through strong atmospheric turbulence

In this letter, error rate performance for space-time block coding (STBC) in free-space optical (FSO) communication systems with direct detection operating over strong atmospheric turbulence channels is analyzed. Based on the modification of the Alamouti code presented by Simon and Vilnrotter, a generalized approach is adopted to consider space-time coded on-off keying (OOK) formats with any pulse shape and reduced duty cycle, allowing the increase of the peak-to-average optical power ratio (PAOPR) and, hence, a relevant improvement in error rate performance. Simulation results are further demonstrated to confirm the analytical results
Modification of the Hepatic Mitochondrial Proteome in Response to Ischemic Preconditioning following Ischemia-Reperfusion Injury of the Rat Liver

Background/Aim: Ischemic preconditioning (IPC) may reduce hepatic ischemia-reperfusion (IR) injury, but efficacy of IPC on mitochondrial proteome is not demonstrated. We investigated how IPC modifies the mitochondrial proteome after IR injury. Methods: Rats were subjected to 25 min of portal triad crossclamping (IR group, n = 8). In the IPC group (n = 8), 10 min of temporal portal triad clamping was performed before 25 min of portal clamping. Samples were obtained after 24 h. The mitochondrial inner-membrane potential was measured by the uptake of a lipophilic cationic carbocyanine probe and mitochondrial proteome was also investigated using 2-dimensional differential in-gel electrophoresis and liquid chromatography-tandem mass spectrometry. Results: Mitochondrial inner-membrane potential and glutathione were lower and serum transaminase was higher in the IPC group than in the IR group. The mitochondrial precursor of aldehyde dehydrogenase 2 and α-methylacyl-CoA-racemase were upregulated in the IPC group in comparison to the IR group. In contrast, protein disulfide-isomerase A3 precursor, 60S acid ribosomal protein P0, carbonic anhydrase 3 and superoxide dismutase were significantly more downregulated in the IPC group than in the IR group. Conclusions: A hepatoprotective effect by IPC was not shown; however, IPC caused significant up- or downregulation of several mitochondrial proteins.
Increased lipid peroxidation in patients with non‐alcoholic fatty liver disease and chronic hepatitis C as measured by the plasma level of 8‐isoprostane

Background: Oxidative stress plays an important role in the pathogenesis of chronic liver diseases. The plasma level of 8‐isoprostane, a product of lipid peroxidation, is a marker of oxidative stress in vivo. The aim of the present study was to clarify whether the degree of lipid peroxidation, as measured by the plasma level of 8‐isoprostane, influences the progression of chronic liver diseases and hepatocarcinogenesis.
cDNA Cloning, Gene Organization, and Chromosomal Localization of a Human Mercurial Insensitive Water Channel

Two distinct cDNAs encoding a human mercurial insensitive water channel (hMIWC) were cloned from a fetal brain cDNA library. The longest open reading frame of cDNA clone hMIWC1 encoded 301 amino acids with 94% identity to rat MIWC (Hasegawa, H., Ma, T., Skach, W., Matthay, M. M., and Verkman, A. S. (1994) J. Biol. Chem. 269, 5497-5500). A second cDNA (hMIWC2) had a distinct 5′-sequence upstream from base pair (bp) −34 in clone hMIWC1 and contained two additional in-frame translation start codons. Expression of hMIWC cRNAs in Xenopus oocytes increased osmotic water permeability by 10-20-fold in a mercurial insensitive manner. Cell-free translation in a reticulocyte lysate/microsome system generated single protein bands at 30 kDa (hMIWC1) and 32-34 kDa (hMIWC2) without glycosylation. Northern blot and polymerase chain reaction/Southern blot analysis showed expression of mRNA encoding hMIWC in human brain muscle heart, kidney, lung, and trachea. Analysis of hMIWC genomic clones indicated two distinct but overlapping transcription units from which multiple hMIWC mRNAs are transcribed. The promoter region of hMIWC1 was identified and contained TATA, CAAT, AP-1, and other regulatory elements. Primer extension revealed hMIWC1 transcription initiation at 46 bp downstream from the TATA box. There were three introns (lengths 0.9, 0.2, and 6 kilobases) in the hMIWC1 coding sequence at bp 381, 546, and 627. A distinct 5′-sequence in clone hMIWC2 suggested an alternative upstream transcription initiation site. Two alternatively spliced, nonfunctional hMIWC transcripts with exon 3 deletion and partial exon 4 deletion were identified. A poly(A) signal sequence was identified at 138 bp downstream of the translation stop codon. Genomic Southern blot analysis indicated the presence of a single copy hMIWC gene; chromosome-specific polymerase chain reaction and in situ hybridization localized hMIWC to human chromosome 18q22. The structural organization of the hMIWC gene represents a first step in definition of hMIWC differential expression, regulation, and possible role in human disease.
Safety and cost benefits of bilateral total knee replacement in an acute hospital

Background: Total knee arthroplasty of both knees under the one anaesthetic has become a common procedure. Benefits reported include a shorter overall hospital stay and reduced costs. The published studies come from university associated tertiary referral hospitals with well‐established research establishments and a vast experience of joint replacement. This study examines the experience of a small hospital to see if similar benefits can be achieved.
Cost-savings and economic benefits due to the assistive robotic manipulator (ARM)

Besides the social and personal benefits of a rehabilitation robot, the direct cost-savings and other (indirect) economic benefits, or effectiveness, are of major importance to party who pays for (or reimburses) the rehabilitation robot. This paper gives an overview of these cost-savings and, on a larger scale, economic benefits of the assistive robotic manipulator (arm) rehabilitation robot.
Homology Between the MPB70 and MPB83 Proteins of Mycobacterium bovis BCG

Isolation of MPB83 from Mycobacterium bovis BCG Tokyo culture fluid is described. MPB70 and MPB83 have similar molecular mass as judged by SDS‐PAGE but differ in isoelectric points. Peptides isolated after CNBr cleavage of MPB83 revealed extensive homology as well as distinct differences from corresponding parts of the amino acid sequence deduced from the mpb70 gene cloned by Terasaka et al. Antibodies produced by immunization with MPB70 and MPB83 had distinctly different fine specificity revealing cross‐reactivity between the proteins. These findings indicate that two distinct, homologous genes code for these proteins. Sensitization with live BCG Tokyo also induced T cell responses to MPB83 with development of delayed type hypersensitivity in guinea pigs.
Sparse antenna array configurations in large aperture synthesis radio telescopes

This paper presents the trade-offs between sparse versus dense and regular versus irregular arrays for the station configuration of the LOFAR low band antenna. The relation between these parameters and the element patterns, station beam patterns, effective area, receiver noise temperature, tapering opportunities and the field of view (or beam width) are presented. A method is proposed and evaluated to suppress the peak grating lobe level in an aperture synthesis telescope consisting of regular sparse stations
TRABALHO, FORMAÇÃO E CURRÍCULO - PARA ONDE VAI A ESCOLA?

Este livro e fruto de um senllnano realizado em 1998, pelo Programa de Pos-Graduacao em Educacao: "Historia, Politica e Sociedade" da PUC-SP e constitui-se numa leitura imprescindivel para todos que pretendem aprofundar a compreensao sobre os vinculos entre trabalho e educacao na atualidade.
PLASMA INSULIN IN ORGANIC HYPERINSULINISM: COMPARATIVE EFFECTS OF TOLBUTAMIDE, LEUCINE AND GLUCOSE.

Concentrations of plasma insulin were determined in peripheral blood before and after the administration of tolbutamide, leucine, glucose and glucagon to 13 patients with insulinoma. Content or concentration, or both, of extractable insulin was determined in the tumors of 11 patients. The means of maximal increases in plasma insulin were excessive after tolbutamide (576 μU/ml), after leucine (211 μU/ml) and after glucose (384 μU/ml). Small increases in concentrations of plasma leucine effected excessive increases in concentrations of plasma insulin in some of the patients with insulinoma. Concentrations of insulin in 11 tumors ranged from 0.02 to 60.75 U/g. Patients whose tumors contained smaller amounts of insulin had lesser increments in plasma insulin after administration of tolbutamide, leucine and glucose and were more likely to have “falsely negative” blood glucose responses to tolbutamide. Hyperglycemia occurring after removal of an insulinoma was associated with hypoinsulinism and disappeared in t.
6-methylprednisolone 'mini-pulses': a new modality of glucocorticoid treatment in systemic onset juvenile chronic arthritis.

From 1989 to 1994 we have been following in our Department 22 patients (12 males, 10 females, age range 1-13.5 years) affected by sJCA who underwent glucocorticoid (GC) treatment. These patients were randomised to receive for 6 months two different GC schedules: group A (12) received 6 methylprednisolone (6MP) i.v. for 3 days with 5 mg/kg/d and for an additional 3 days at 2.5 mg/kg/d followed by po prednisone (1 mg/kg/d); group B (10) received po prednisone (1 mg/kg/d). A remarkable decrease of disease activity and fever score and a prompt improvement of joint involvement were observed. A CPR serum concentration decrease associated to a consistent increase of Hb over baseline values were disclosed in group A. GC cumulative daily requirement was significantly lower in group A. Four patients from group B but only one from group A developed a cushingoid appearance: no differences of BMI were found in the two groups. Our study shows that in sJCA patients i.v. GC mini pulses are effective on early clinical and biological parameters of inflammation and requires a lower cumulative daily dosage than conventional oral GC treatment.
Title : What positive gains do women obtain from peer support interventions and what barriers preclude higher initiation and duration of exclusive breastfeeding ? A systematic review

Now recognised as a worldwide public health issue the significance of promoting and encouraging exclusive breastfeeding has been acknowledged by The World Health Organisation (WHO) and The United Nations Children’s Fund (UNICEF). Documented policies regarding the importance of facilitating the support of breastfeeding women is currently receiving worldwide recognition (WHO 2011, WHO and UNICEF 2003). This literature review will examine the provision of support mechanisms for breastfeeding mothers focusing upon peer support in encouraging initiation and maintaining exclusivity of breastfeeding; consideration will also be given to any barriers that may exist in preventing higher success rates.
Health Status and Behavioral Outcomes for Youth Who Anticipate a High Likelihood of Early Death

OBJECTIVE: The relationship between adolescents' perceived risk for dying and their involvement in risk behaviors is unknown. We sought to determine the proportion of US youth who anticipate a high likelihood of early mortality and relationships with health status and risk behaviors over time. METHODS: We analyzed data from times 1 (1995), 2 (1996), and 3 (2001–2002) of the National Longitudinal Study of Adolescent Health, a nationally representative sample of youth in grades 7 through 12. The relationship between perceived risk for premature mortality and health behaviors/outcomes was assessed by using bivariate and multivariate analyses. RESULTS: At time 1, 14.7% of the 20594 respondents reported at least a 50/50 chance that they would not live to age 35. In adjusted models, illicit drug use, suicide attempt, fight-related injury, police arrest, unsafe sexual activity, and a diagnosis of HIV/AIDS predicted early death perception at time 2, time 3, or both (adjusted odds ratios: 1.26–5.12). Conversely, perceived early mortality at time 1 predicted each of these behaviors and outcomes, except illicit drug use, at time 2 or time 3, most strongly a diagnosis of HIV/AIDS (adjusted odds ratios: 7.13 [95% confidence interval: 2.50–20.36]). CONCLUSIONS: Adolescent involvement in risk behaviors predicted a belief in premature mortality 1 and 7 years later. Reciprocally, adolescents' perceived risk for early death predicted serious health outcomes, notably a diagnosis of HIV/AIDS in young adulthood. Given its frequency and influence on behavior and health, adolescents' perceived risk for early death should be incorporated into psychosocial assessments and interviews.
A Microleakage evaluation of Sonicfill , Silorane-based and nanofill methacrylate-based composites ( a comparative study ) ”

Introduction Resin composites have been improved greatly nowadays, and many advancement has been reached. However, polymerization shrinkage is still a challenging drawback of composite resin restorations. Objectives this study was conducted with aim of comparing, in vitro, the marginal adaptation of three different, low shrinkages, direct posterior composites. Materials and Methods The following composites, Sonic fill® (nanohybrid composite), Filtek® P90 (Silorane-based composite) and Filtek® Z350 (nanofill composite) utilizing a standardized Class V cavity preparation followed by thermal cycling. Sixty human premolars prepared with standardized Class V cavities. The specimens were divided into three groups (n=20) according to the material used. All specimens were subjected to thermocycling at (5° to 55°C), then immersed in 2% methylene blue dye for 24hrs. For each group microleakage at the occlusal and gingival regions was measured by determining dye penetration using scoring system under steromicroscope at 100x. Results The statistical analysis of the results showed that, silorane-based composite exhibited the lowest microleakage, with statistical significant difference (p< 0.05) when compared with Sonicfill® composite and Filtek® Z350 XT nanofill composite. On the other hand, the results of this study showed non-significant difference between Sonic fill® composite and Filtek® Z350 XT. Also, there is a significant difference ( < 0.01) in dye penetration between occlusal and gingival regions within each group. Conclusion Taking into consideration the types of composites tested in this study, we recommend the clinical use of Siloran-based composite material for higher microleakage resistance and better marginal seal.
Image authentication by motion blur consistency verification

Fake images have become ubiquitous today in society, as they can be created at the expense of a few clicks using photo manipulation software. The detection of splicing in images has received research attention in recent years. In this paper, we present a novel method of detecting splicing in images, using discrepancies in motion blur. We use motion blur estimation through spectral matting in order to detect inconsistencies between the spliced region and the rest of the image. Experimental results show the effectiveness of our technique. Comparison studies show that this technique performs better than existing blur-based techniques when applied to motion blur.
Provable Secure Brand-new Multi-auction Mechanism with Dynamic Identity

Different from traditional auctions, electronic auctions provide a platform to allow bidders and auctioneers merchandise to each other over network anytime and anywhere. Auctioneers can publish information of goods, and bidders can choose the interested targets through this bidding platform. To ensure the fairness and security of electronic auctions, Li et al. have proposed a practical electronic auction scheme which can confirm the requirement of strong anonymity, bidding privacy, and secret bidding price. However, we have found out that Li et al.’s scheme may lurk the risk of the denial-of-service attack during the bidding phase in a sealed-bid auction. Thus, we propose a brand-new sealed-bid auction mechanism, in which the essentials of e-auction can be firmly preserved. In particular, each bidder only needs to register at the center once and then can join to multiple plays launched by different auc-tioneers. Moreover, the correctness of mutual authentication is confirmed according to the BAN logic model.
Mechanical Properties of Elastomeric Impression Materials: An In Vitro Comparison

Purpose. Although new elastomeric impression materials have been introduced into the market, there are still insufficient data about their mechanical features. The tensile properties of 17 hydrophilic impression materials with different consistencies were compared. Materials and Methods. 12 vinylpolysiloxane, 2 polyether, and 3 hybrid vinylpolyether silicone-based impression materials were tested. For each material, 10 dumbbell-shaped specimens were fabricated (n = 10), according to the ISO 37:2005 specifications, and loaded in tension until failure. Mean values for tensile strength, yield strength, strain at break, and strain at yield point were calculated. Data were statistically analyzed using one-way ANOVA and Tukey's tests (α = 0.05). Results. Vinylpolysiloxanes consistently showed higher tensile strength values than polyethers. Heavy-body materials showed higher tensile strength than the light bodies from the same manufacturer. Among the light bodies, the highest yield strength was achieved by the hybrid vinylpolyether silicone (2.70 MPa). Polyethers showed the lowest tensile (1.44 MPa) and yield (0.94 MPa) strengths, regardless of the viscosity. Conclusion. The choice of an impression material should be based on the specific physical behavior of the elastomer. The light-body vinylpolyether silicone showed high tensile strength, yield strength, and adequate strain at yield/brake; those features might help to reduce tearing phenomena in the thin interproximal and crevicular areas.
Screening for cognitive deficits after stroke: a comparison of three screening tools

Objective: To assess the concurrent validity of three screening tests for focal cognitive impairments after stroke. Design: Comparison of results from the screening tests with those from a more comprehensive neuropsychological battery. Setting: Stroke rehabilitation wards of a general hospital and a rehabilitation hospital. Subjects: Forty-nine stroke patients (25—91 years, 35% women). Measures: Screening tests were the Cognistat, the Screening Instrument for Neuropsychological Impairments in Stroke (SINS) and the Clock Drawing Test. Health professionals, blind to the results of the reference method, did the screening. Reference method was a neuropsychological assessment based on the Norwegian Basic Neuropsychological Assessment, classifying the patients as `impaired' or `not impaired' within the following cognitive domains: language, visuospatial function, attention and neglect, apraxia, speed in unaffected arm, and memory. Results: The best sensitivity (95% confidence interval) was achieved for language problems by Cognistat, naming (80%, 44—98); for visuospatial dysfunction, attention deficits and reduced speed, all by SINS visuocognitive (82%, 60—95, 72%, 39—94, and 78%, 56—93, respectively); and for memory problems by Cognistat memory (69%, 52—87). The data were insufficient to assess any subtest for apraxia. Sensitivity in detecting deficits in any domain was 82% (71—94) for the Cognistat composite score, 71% (57—85) for the SINS composite score, and 63% (49—78) for the most sensitive score of the Clock Drawing Test. Conclusion: The Cognistat and the SINS may be used as screening instruments for cognitive deficits after stroke, but cannot replace a neuropsychological assessment. The Clock Drawing Test added little to the detection of cognitive deficits.
LAPM: The Location Aware Prediction Model in Human Sensing Systems

The mobile human social network actually might be the hugest and best “sensor network” because of the explosive growth in social network content. Nowadays, more and more mobile social applications offer a much easier way for people to share their feeling including vision, haptic, hearing, and smell with the location information by words, images, or even videos. These new sharing methods appearing in the mobile social network actually give us a precious chance to sense the world. Extra systems, which are specialized in particular sensing, do not need to be created any more. The specific sensing data can be acquired from the social network by handling the heterogeneous data. The contribution of this paper lies in developing a model that collects samples considering the relevancy from the perspective of location from different mobile social networks and estimating the occurrence likelihood of the perceived event with collected samples. The simulations and real-world case studies are also developed to verify the reliability of the model and the effectiveness of the Location Aware EM algorithm.
The Transcriptome Profile of Human Embryonic Stem Cells as Defined by SAGE

Human embryonic stem (ES) cell lines that have the ability to self‐renew and differentiate into specific cell types have been established. The molecular mechanisms for self‐renewal and differentiation, however, are poorly understood. We determined the transcriptome profiles for two proprietary human ES cell lines (HES3 and HES4, ES Cell International), and compared them with murine ES cells and other human tissues. Human and mouse ES cells appear to share a number of expressed gene products although there are numerous notable differences, including an inactive leukemia inhibitory factor pathway and the high preponderance of several important genes like POU5F1 and SOX2 in human ES cells. We have established a list of genes comprised of known ES‐specific genes and new candidates that can serve as markers for human ES cells and may also contribute to the “stemness” phenotype. Of particular interest was the downregulation of DNMT3B and LIN28 mRNAs during ES cell differentiation. The overlapping similarities and differences in gene expression profiles of human and mouse ES cells provide a foundation for a detailed and concerted dissection of the molecular and cellular mechanisms governing their pluripotency, directed differentiation into specific cell types, and extended ability for self‐renewal.
Semi-user-level communication architecture

This paper introduces semi-user-level communication architecture, a new high-performance light-weighted communication architecture for inter-node communication of clusters. Different from traditional kernel-level networking architecture and user-level communication architecture, semi-user-level communication architecture removes OS kernel from its message-receiving path while reserves an OS trapping on its message-sending path. No interrupt handling is needed. This new communication architecture doesn't support user-level access to network interface. It provides good portability, security, and support for heterogeneous networking environment and usage of large memory. Semi-user-level communication architecture has been implemented on a SMP workstation cluster system called DAWNING-3000, which is interconnected through Myrinet. Communication performance results are given and overhead distribution is analyzed.