Miracle-dz/UniFAR-FTUs huggingface dataset:
COVID-19 Pneumonia Precipitating Acute Anterior Wall Myocardial Infarction With Large Left Ventricular Apical Thrombus

Initial reports suggest an increased thrombotic risk in coronavirus disease 2019 (COVID-19). We present a case of COVID-19 pneumonia that precipitated chest pain, an acute anterior wall ST-elevation myocardial infarction on the fifth day of hospitalization resulting in large left ventricular apical thrombus.
Robust portfolio rebalancing with cardinality and diversification constraints

In this paper, we develop a robust conditional value at risk (CVaR) optimal portfolio rebalancing model under various financial constraints to construct sparse and diversified rebalancing portfolios. Our model includes transaction costs and double cardinality constraints in order to capture the trade-off between the limit of investment scale and the diversified industry coverage requirement. We first derive a closed-form solution for the robust CVaR portfolio rebalancing model with only transaction costs. This allows us to conduct an industry risk analysis for sparse portfolio rebalancing in the absence of diversification constraints. Then, we attempt to remedy the hidden industry risk by establishing a new robust portfolio rebalancing model with both sparse and diversified constraints. This is followed by the development of a distributed-version of the Alternating Direction Method of Multipliers (ADMM) algorithm, where each subproblem admits a closed-form solution. Finally, we conduct empirical tests to compare our proposed strategy with the standard sparse rebalancing and no-rebalancing strategies. The computational results demonstrate that our rebalancing approach produces sparse and diversified portfolios with better industry coverage. Additionally, to measure out-of-sample performance, two superiority indices are created based on worst-case CVaR and annualized return, respectively. Our ADMM strategy outperforms the sparse rebalancing and no-rebalancing strategies in terms of these indices.
Assessing the Role of Carbon Capture and Storage in Mitigation Pathways of Developing Economies

The Paris Agreement has set out ambitious climate goals aiming to keep global warming well-below 2 °C by 2100. This requires a large-scale transformation of the global energy system based on the uptake of several technological options to reduce drastically emissions, including expansion of renewable energy, energy efficiency improvements, and fuel switch towards low-carbon energy carriers. The current study explores the role of Carbon Capture and Storage (CCS) as a mitigation option, which provides a dispatchable source for carbon-free production of electricity and can also be used to decarbonise industrial processes. In the last decade, limited technology progress and slow deployment of CCS technologies worldwide have increased the concerns about the feasibility and potential for massive scale-up of CCS required for deep decarbonisation. The current study uses the state-of-the-art PROMETHEUS global energy demand and supply system model to examine the role and impacts of CCS deployment in a global decarbonisation context. By developing contrasted decarbonisation scenarios, the analysis illustrates that CCS deployment might bring about various economic and climate benefits for developing economies, in the form of reduced emissions, lower mitigation costs, ensuring the cost efficient integration of renewables, limiting stranded fossil fuel assets, and alleviating the negative distributional impacts of cost-optimal policies for developing economies.
Group-Based Parent Education Intervention for Nonresident Fathers

Research indicates that children with involved fathers fare better than children with disengaged fathers. In response, 4 Your Child provides fatherhood-specific parent education and solution-focused case management services aimed at helping nonresident fathers increase their capacity for taking more active roles in their children’s lives. The purpose of this study was to present the results of preliminary analyses from a sample of 508 nonresident fathers enrolled in 4 Your Child. The results reveal high levels of participant satisfaction and statistically significant increases in parenting knowledge and conflict resolution skills for program participants from pre- to postintervention. Recommendations for future research and practice are also included.
Growth medium and electrolyte—How to combine the different requirements on the reaction solution in bioelectrochemical systems using Cupriavidus necator

Microbial electrosynthesis is a relatively new research field where microbial carbon dioxide fixation based on the energy supplied by a cathode is investigated. Reaction media used in such bioelectrochemical systems have to fulfill requirements of classical biotechnology as well as electrochemistry. The design and characterization of a medium that enables fast electroautotrophic growth of Cupriavidus necator in microbial electrosynthesis was investigated in detail. The identified chloride‐free medium mainly consists of low buffer concentration and is supplied with trace elements. Biotechnologically relevant parameters, such as high‐specific growth rates and short lag phases, were determined for growth characterization. Fast growth under all conditions tested, i.e. heterotrophic, autotrophic and electroautotrophic was achieved. The lag phase was shortened by increasing the FeSO₄ concentration. Additionally, electrochemical robustness of the reaction media was proven. Under reductive conditions, no deposits on electrodes or precipitations in the media were observed and no detectable hydrogen peroxide evolved. In the bioelectrochemical system, no lag phase occurred and specific growth rate of C. necator was 0.09 h⁻¹. Using this medium shortens seed train drastically and enables fast electrobiotechnological production processes based on C. necator.
Construction of an Agrobacterium Mediated RNAI Genetic Transformation Vector Targeting the Replicase Gene of Indian cassava mosaic virus and Evaluation of Their Transformation Ability in Cassava Immature Leaf Lobes

Cassava mosaic virus is one of the major problems affecting cassava industry in India. Currently there are no effective strategy to completely protect cassava from cassava mosaic viruses. In order to attain cassava mosaic virus resistance RNAi vectors targeting the replicase gene of Indian cassava mosaic virus is constructed in this study. Their efficiency to transform cassava immature leaf lobes were also studied here. Replicase gene of Indian cassava mosaic virus in Tamilnadu are cloned and sequenced. Conserved domains are identified and sub cloned to CSIRO RNAi vector system and transformation studies are done in immature cassava leaves. Two different RNAi vectors were constructed, utilizing a conserved 440bp of 5’ end of ICMV Rep (AC1) gene which also corresponds to a part of AC4 gene, and functions as a viral RNAi suppressor protein. The partial Rep gene of ICMV was cloned in sense and anti-sense orientations in the RNAi intermediate vector, pHANNIBAL. After cloning into pHANNIBAL, the cloned RNAi gene cassettes of ICMV is released and cloned into the binary vector, pART27, which contains the kanamycin-resistance gene as a plant selectable marker. In order to use hygromycin as a selection agent in cassava genetic transformation, RNAi–Rep gene cassettes of ICMV were cloned into pCAMBIA1305.2. These constructs were named pICR1 and pICR2 respectively. The Genetic transformation studies in cassava leaves done using pICR2 vector could generate PCR positive plants. An agrobacterium mediated replicase RNAi vector is developed and that can be transformed into cassava immature leaf lobes. Their efficiency to silence the Indian cassava mosaic virus should be studied further.
On-chip micro pressure sensor for microfluidic pressure monitoring

In this work, a novel on-chip micro pressure sensor was developed for microfluidic pressure monitoring. Polydimethylsiloxane (PDMS) microfluidic chip contained a working fluid channel with a sealed detection channel beneath it. Any change in pressure in the working fluid channel would change the volume of the detection channel. A mixture of two immiscible fluids was sealed in the detection channel. The pressure of the working fluid can be monitored by measuring the interface displacement of the two fluids in the detection channel. A PDMS film between the working channel and detection channel can avoid cross-contamination between fluids. We acquired a calibration curve of the pressure sensor for measurement and optimized the performance of the sensor through parametric studies. Moreover, two pressure sensors were integrated into a microchip to characterize the pressure drop in the microchannel. The developed pressure sensor is inexpensive and easy to be integrated into microfluidic devices to monitor the flow conditions for cell culture, fluid mixing, and droplet manipulation.
Synthesis and characterisation of biodegradable liquid crystal elastomer with the property of shape recovery

ABSTRACT Novel shape recovery biodegradable liquid crystal (LC) elastomer is reported here for the first time. The method of synthesis of the shape memory biodegradable LC elastomer has been explored. During the reaction, the LC molecules are added to form LC polymers, and then cross-linking agent is added to form a cross-linked LC elastomer. The LC elastomer in this work is hydrophilic. In vitro degradation of the LC elastomer films in a buffer of pH 7.4 at 37°C shows that the LC elastomer has good degradability. The biodegradable LC elastomer exhibits liquid crystalline behaviour and has shape memory ability. Its shape memory and actuating properties also have been studied. The reversible transition from liquid crystalline phase to isotropic phase is utilised as the switching mechanism for these stimuli-responsive materials. When reheating the LC elastomer to 120°C, the shape will recover. Graphical Abstract
Learning linear equations: capitalizing on cognitive load theory and learning by analogy

ABSTRACT Capitalizing on cognitive load theory and learning by analogy, we propose two instructional methods to learn a complex linear equation (e.g. two-step equation) by building on prior knowledge of a simpler linear equation (e.g. one-step equation). We will examine the proposal theoretically in this paper. In line with the design principles of cognitive load theory, we propose to strengthen students’ prior knowledge of simpler linear equations before they learn complex linear equations with the aid of worked examples. Because a subset of the complex linear equation shares the same schema as the simpler linear equation, students can draw on their schema for the simpler linear equation to understand the complex linear equation, thus alleviating the limitation on working memory load. Based on the principles of learning by analogy, we place a simpler linear equation and a complex linear equation side-by-side and label the solution procedure of both linear equations to encourage active analogical comparison between these two equations. Making both the simpler linear equation and the complex linear equation visible to learners may help to reduce cognitive load demands in retrieving the simpler linear equation in order to facilitate the learning of the complex linear equation.
B-type natriuretic peptide levels and its correlation with left ventricular functions and heart failure in patients of acute coronary syndromes

Background: This study was designed to measure levels of B-type natriuretic peptide (BNP) across entire spectrum of acute coronary syndrome (ACS) and to find its correlation with left ventricular functions and heart failure. Methods: We measured BNP levels at baseline in 100 consecutive patients between 24-96 hours after the onset of ischemic symptoms in patients of ACS. Echocardiography was performed in all patients between day 2-5 after the index diagnosis and stabilizing the patients. Results: The BNP levels were raised across the entire spectrum of ACS, with levels (>80 pg/ml) in 32.2% of patients with ST segment-elevation myocardial infarction (STEMI), in 24% with non-ST segment-elevation myocardial infarction (NSTEMI), and in 16.6% with unstable angina (UA) respectively. High BNP levels were associated with greater increase in LV end-systolic volumes (r=+0.545, p<0.001) (LVESV) and end-diastolic volumes (LVEDV) (r=+0.336, p<0.001). There was a negative correlation between BNP levels and left ventricular ejection fraction (LVEF) (r=-0.394, p<0.002). BNP levels were significantly raised (156.0±45.1 vs 57.7±18.3 pg/ml, p<0.02) in patients developing symptomatic clinical heart failure, irrespective of LVEF ≤40%. Conclusions: Integrated use of echocardiography and BNP levels provide powerful incremental assessment of cardiac functions, clinical status, and outcome across the entire spectrum of acute coronary syndromes (ACS). Increased BNP levels are associated with progressive ventricular dilatation, LV-dysfunction, development of clinical heart failure and is associated with poor prognosis in patients of ACS.
Selected Aspects Of The Crispr-Cas Biology And Applications

Abstract The clustered regularly interspaced short palindromic repeats (CRISPR) and CRISPR-associated proteins are components of the adaptive immunity system, protecting against foreign DNA, which are present in many bacteria species. Recent years have brought extensive research on this system however, not all of its biological properties have been discovered so far. It was recently discovered that CRISPR-Cas can regulate the formation of biofilm and is closely associated with the DNA repair system in bacterial cells. It is also likely that some of the spacer sequences are complementary to short sequences in the bacterial genome, which may have an influence on regulation of bacterial genes, e.g. virulence factors. Besides, phages can synthesize anti-CRISPR genes, which could be of use in the future for the purpose of development of an alternative therapy against multi-drug resistant bacterial strains. Here we present an elementary characteristic of CRISPR-Cas system, including the structure and the brief mechanism of action, systematic classification and its importance for medicine and biotechnology issues. We would like to stress the huge potential of CRISPR-Cas by discussing the selected but varied aspects. 1. Introduction. 2. Structure, operation and differences. 3. Bacterial typing. 4. Correlation with bacterial pathogenicity. 5. Potential tool for medicine. 5.1. CRISPR-tool for genome editing. 5.2. Instances of CRISPR-tool strategies in medicine. 6. Phage response. 7. Conclusions
Underrepresented minority students receive lower grades and have higher rates of attrition across STEM disciplines: A sign of inequity?

ABSTRACT Underrepresented minority (URM) students are subjected to historically rooted inequities when pursuing an education, especially in STEM disciplines with little diversity. In order to make STEM education equitable and inclusive, evidence for how students from different racial/ethnic demographics are faring is necessary. We use 10 years of institutional data at a large public US-based university to investigate trends in the majors that Asian, URM, and White students declare, drop, and complete. We find that URM students drop most majors at higher rates compared to other students, particularly in physics and economics. We find alarming GPA trends in that URM students consistently earn lower grades than their Asian and White peers. In some STEM disciplines, the URM students who earn a degree are earning the same grades as the Asian and White students who dropped the major. These troubling trends may signify lack of sufficient support, mentoring, and guidance for the URM students who are already severely disadvantaged particularly at a primarily White institution. These findings call for greater resources and effort for making learning environments equitable and inclusive so that many URM students who come to college with severe disadvantages are appropriately supported and can excel similar to other students.
Toward a Tradable Low-Carbon Cement Standard: Policy Design Considerations for the United States

CONTENTS Executive Summary . 1 1. The Decarbonization Challenge for Cement and Concrete . 5 2. The Cement and Concrete Sector . 7 3. Decarbonizing the Cement and Concrete Industry . 10 4. Designing a Low-Carbon Cement Standard . 11 5. Legal Avenues for a Low-Carbon Cement Standard . 17 6. Conclusions and Recommendations . 17 Appendices . 19 Abbreviations . 23 Endnotes.23 References . 24 Acknowledgments . 33
Dropout of Infertility Treatments Among Iranian Infertile Couples: A Cohort Study

Background: Many infertile couples seek Assisted Reproductive Technologies (ART) to achieve pregnancy. However, a high proportion of them dropout treatment due to different reasons. In the present study we aimed to evaluate the dropout/continuity rate of infertility treatments and related factors among Iranian couples.Methods: The present retrospective cohort study was conducted on 380 eligible infertile women in four groups (95 people in each group) based on causes of infertility (male, female, unexplained, both) from April 2018 to March 2019 in infertility centers of Qom. The individuals had at least one unsuccessful IVF/ICSI (In Vitro Fertilization/ Intra Cytoplasmic Sperm Injection) or FET (Frozen Embryo Transfer) cycle. Participants were considered as treatment discontinuer if they did not refer to the infertility clinics at least six months after the failure of treatment. The research data were collected using medical records and telephone interviews.Results: Incidence dropout rate of infertility treatments was 42.9%. Related factors in dropout were number of unsuccessful treatments (P<0.001), age of women (p= 0.01), age of men (p= 0.02), and type of infertility (primary or secondary) (p= 0.004). Treatment dropout was higher in couples, who had one experience of unsuccessful treatment (60.1%), than those who had twice or more experiences (21.7%). Conclusions: Dropout rate of infertility treatments was relatively high; and some demographic factors were associated with treatment continuation. It seems that couples, who have primary infertility and one unsuccessful infertility treatment, were at a greater risk of dropout and its consequences. This phenomenon can be due to the lack of awareness and adequate information.
Iterative Receiver Design for Polar-Coded SCMA Systems

An edge-cancellation-aided iterative detection and decoding (EC-IDD) algorithm is proposed for polar-coded sparse code multiple access (SCMA), which jointly performs Gaussian-approximated message passing (GA-MP) detection of SCMA supported by the soft list decoding (SLD) of polar codes. A reduced-edge factor graph is formulated in each consecutive iteration with the aid of the cyclic redundancy check (CRC) and EC. Based on the simplified factor graph, the EC-IDD gradually reduces its complexity in each subsequent iteration, while improving the bit error rate (BER) performance, compared to the state-of-the-art joint detection and decoding (JDD) of polar-coded SCMA. Furthermore, an embedded decision-directed channel estimator (DD-CE) is proposed for our polar-coded SCMA system under realistic imperfect channel state information (CSI). Our simulation results demonstrate that the proposed EC-IDD achieves better BER performance than the state-of-the-art JDD under both perfect and imperfect CSI, despite achieving a complexity reduction of 92%. Finally, the BER of the proposed joint DD-CE and EC-IDD algorithm under imperfect CSI converges to that of EC-IDD operating under perfect CSI.
Well‐Dispersed Fe2O3 Nanoparticles on g‐C3N4 for Efficient and Stable Photo‐Fenton Photocatalysis under Visible‐Light Irradiation

In this study, a highly efficient heterogeneous photo-Fenton system (Fe2O3/g-C3N4/H2O2/visible light) has been developed. The heterogeneous catalyst Fe2O3/g-C3N4 in this system was successfully prepared by growing Fe2O3 nanoparticles on the surface of g-C3N4. The Fe2O3 nanoparticles could achieve high dispersion on the surface of g-C3N4 and form a heterojunction with g-C3N4 to improve the charge separation. In addition, the combination of the Fenton's reagent Fe2O3/H2O2 and the photocatalyst g-C3N4 greatly enhances the rate of the Fenton's reaction with the assistance of the photocatalytic process. The results showed that the Fe2O3/g-C3N4 catalyst had a superior catalytic activity as compared with the single component of Fe2O3 or g-C3N4 and the mechanical mixture of Fe2O3 and g-C3N4. The catalyst prepared with 3 mL of FeCl3 aqueous solution shows the best photo-Fenton photocatalytic efficiency with a reaction rate constant of 0.02461 mg L–1 min–1, which is about 45.4, 8.4 and 7.2 times larger than that of pure Fe2O3 (0.0005418 mg L–1 min–1), pure g-C3N4 (0.00294 mg L–1 min–1) and the mechanically mixed Fe2O3/g-C3N4 (0.0034 mg L–1 min–1), respectively. A possible mechanism for the visible-light-irradiated photo-Fenton photocatalysis is proposed, and the Fe2O3/g-C3N4 catalyst exhibited stable performance without obvious loss of catalytic activity after four successive runs, showing a good application prospect for the photo-oxidative degradation of organic contaminants in wastewater.
Analisis peran guru dalam meningkatkan minat baca peserta didik di sekolah dasar

The research was conducted to analyze the teacher’s role to increasing students reading interest. The teacher’s role is important because teacher guides, encourages, and monitors the students. Increasing students reading interest is important. Some students don’t like reading because of a lack of reading habits and affected by technological advances. This research is a qualitative research with descriptive methods and a case study approach. The research was conducted at Karangasem 3 Elementary School in 2020. The subject is the teacher. The data are obtained from the location, teachers, and students. The data are obtained from observation, interviews, questionnaires, and documentation. The data validity used source and technique triangulation. Analysis using interactive analysis techniques Miles and Huberman. The results showed that the teacher's role in increasing students reading interest was applied by creating, facilitating, motivating, evaluating, and dynamizing reading activities. As a creator, the teacher makes new ideas in reading, as a facilitator the teacher provides physical facilities (infrastructure) and non-physical (services) related to reading activities, as a motivator the teacher always encourages students, as a evaluator, teacher evaluates the achievement of reading activities, and as a teacher dynamic, making reading activities continuity.
Are people having adequate knowledge to prevent COVID-19 pandemic? A cross-sectional study

Background: The Covid-19 pandemic is still going on around the globe and prevention of this pandemic is depend on how much people are aware regarding COVID-19 disease. The present study was conducted with an aim to determine the level of knowledge towards COVID-19 among people.Methods: Present study included cross sectional descriptive survey design which was conducted on 366 participants who visited in university during 2020. Convenient sampling technique was chosen for selection of samples. A self-structured knowledge questionnaire was used for data collection. Descriptive and inferential statistics were used to analyse the data in SPSS.Results: Study findings revealed that there were 343 (93.7%) female participants and were students (86.3%). Overall, more than half (60.1%) of participants had good knowledge while 37.2% had average knowledge on COVID-19. Significant difference was found among participants’ group (p>0.001), gender (p=0.021), education (p=0.002), marital status (p=0.002), age (p=0.021), and inhabitants (p=0.002 Participants showed poor knowledge on COVID-19 susceptibility (81%) and diagnosis (90%) aspects.Conclusions: Study concluded that many people were still had average and poor knowledge on COVID-19. Higher authorities must find the ways for making people more aware on this pandemic to control its impact.