Miracle-dz/UniFAR-FTUs huggingface dataset:
Place Recognition by Per-Location Classifiers

Place recognition is formulated as a task of finding the location where the query image was captured. This is an important task that has many practical applications in robotics, autonomous driving, augmented reality, 3D reconstruction or systems that organize imagery in geographically structured manner. Place recognition is typically done by finding a reference image in a large structured geo-referenced database. In this work, we first address the problem of building a geo-referenced dataset for place recognition. We describe a framework for building the dataset from the street-side imagery of the Google Street View that provides panoramic views from positions along many streets, cities and rural areas worldwide. Besides of downloading the panoramic views and ability to transform them into a set of perspective images, the framework is capable of getting underlying scene depth information. Second, we aim at localizing a query photograph by finding other images depicting the same place in a large geotagged image database. This is a challenging task due to changes in viewpoint, imaging conditions and the large size of the image database. The contribution of this work is two-fold; (i) we cast the place recognition problem as a classification task and use the available geotags to train a classifier for each location in the database in a similar manner to per-exemplar SVMs in object recognition, and (ii) as only a few positive training examples are available for each location, we propose two methods to calibrate all the per-location SVM classifiers without the need for additional positive training data. The first method relies on p-values from statistical hypothesis testing and uses only the available negative training data. The second method performs an affine calibration by appropriately normalizing the learned classifier hyperplane and does not need any additional labeled training data. We test the proposed place recognition method with the bag-of-visual-words and Fisher vector image representations suitable for large scale indexing. Experiments are performed on three datasets: 25,000 and 55,000 geotagged street view images of Pittsburgh, and the 24/7 Tokyo benchmark containing 76,000 images with varying illumination conditions. The results show improved place recognition accuracy of the learned image representation over direct matching of raw image descriptors.
Study of acute myeloid leukaemia with known chromosomal translocations A Thesis Submitted for the Degree of Doctor of Philosophy

II DEDICATION IV LIST OF FIGURES X LIST OF TABLES XIV LIST OF ABBREVIATIONS XV ACKNOWLEDGEMENTS XVIII DECLARATION XIX CHAPTER 1: INTRODUCTION 1 1-1 Haematopoiesis 1 1-2 Regulation of HSC 2 1-3 The cell cycle 4 1-3-1 The G1 check point 5 1-3-2 The synthesis phase (S phase) 5 1-3-3 The G2 check point 5 1-3-4 The M Phase 6 1-4 The hypothesis of Leukaemic stem cells 7 1-5 Leukaemia 7 1-5-1 Definition and classification of acute myeloid leukaemia 7 1-6 Molecular mechanisms of cancer 10 1-6-1 Oncogenes 10 1-6-2 Tumour suppressor genes 10 1-8 Chromosomal Abnormalities in AML 13 1-8-1 Structural chromosomal rearrangements in AML and their prognostic significance 13 1-8-2 Numerical chromosomal rearrangements in AML and their prognostic significance 15 1-9 The two-hit model of leukaemogenesis 20 1-10-2 Mechanisms of formation of copy number changes 23 1-11 Methods used to diagnose AML 24
The Health and Mental Health of Informal Caregivers in Rural and Urban Northern Ireland

Doebler, S. (2015). The Health and Mental Health of Informal Caregivers in Rural and Urban Northern Ireland. Paper presented at Knowledge Exchange Seminar Series (KESS), NI Assembly, Belfast, United Kingdom. http://www.niassembly. gov.uk/assembly-business/research-and-information-service-raise/knowledgeexchange/knowledge-exchange-seminar-series-4-2014-2015/the-health-and-mental-health-of-informalcaregivers-in-rural-and-urban-northern-ireland/
Psychometrics in assessing hepatic encephalopathy – a brief review

Abstract Hepatic encephalopathy is a neuropsychiatric disorder usually associated with severe hepatic insufficiency. It may however be divided into clinical and subclinical groupings. Psychometric testing, serial EEG's, EEG spectral analysis and event related potentials are all presently being used to quantify and differentiate between the various stages of hepatic encephalopathy. We review the use of psychometrics in hepatic encephalopathy and discuss evidence that these findings are comparable with the more objective data of electrophysiological studies. An adequate, simple and inexpensive assessment may be carried out using a battery of psychometric tests which include number connection tests and five pointed star construction.
Conservation of dinitroani-line/phosphorothioamidate site of α-tubulin in Plasmodium species distributed in India

Aim. To evaluate polymorphism of dinitroaniline/phosphorothioamidate binding site in α-tubulin molecules from Plasmodium species (P. falciparum, P. vivax, P. ovale, and P. malariae) and strains discovered in India. Methods. Literature and database search. Bioinformatical comparison of protein sequences and structures. Multiple sequence alignment, phylogenetic profiling, protein structure modeling, etc. Results. 14 complete sequences of α-tubulin from four Plasmodium species were selected from UniProtKB. Despite certain differences in complete sequences of α-tubulin molecules from different Plasmodium species and strains, sites of their interaction with dinitroaniline and phosphorothioamidate compounds were shown to be identical. Conclusions. Complete identity of dinitroaniline/phosphorothioamidate binding sites in all studied isotypes of α-tubulin molecules from P. falciparum, P. vivax, P. ovale, and P. malariae was confirmed. This suggests identity of the ligand-protein interaction mechanism and similar destabilizing effect of dinitroaniline and phosphorothioamidate compounds on microtubules of all Plasmodium species officially registered in India. Keywords: malaria, Plasmodium, α-tubulin, dinitroanilines, phosphorothioamidates, binding site.
The Effectiveness of the Safe Work Practices Safety Program

All too often organizations and employees suffer unnecessarily from the effects of preventable workplace injuries. This study was conducted to determine the overall effectiveness of a behavioral based safety program known as Safe Work Practices in the distribution facilities of ORS Nasco, Inc., which operates nationwide. A substantial reduction in the rate of injury would indicate effectiveness of the program. This study was also conducted to find what variables contribute to an increase in the rate of injury, such as work hours. Data including injury rate and work hours were collected over a four-year period and analyzed for the purpose of this study. The findings concluded, for a myriad of reasons, there was likely not a significant reduction in the rate of injury after implementation of the Safe Work Practices program. However, exploratory analysis provided solid evidence that the number of hours worked at a given facility may be an indicator of the likelihood of injury, ultimately contributing to the necessity of the program. Thus, recommendations for future research were included near the end of the study.
A Survey on Indoor Positioning System using Wi-Fi

The functionality of Wireless indoor positioning systems have increased nowadays. Applications used for navigating through a campus or performing inventory management have wireless indoor positioning as its basis. This paper aims to reflect our survey on the development of various techniques and methods used to implement indoor positioning using Wifi. Three Trilateration techniques (TOA, TDOA and RSS) along with Triangulation (basic mathematical technique) are studies and compared on the basis of hardware requirements and accuracy. Later we analyze the technique of location fingerprinting with the help of the above mentioned techniques in an attempt to combine classical positioning methods to minimize hardware usage and increase precision for location detection. Index Terms Time of Arrival, Time Difference of Arrival, Received Signal Strength, Fingerprinting, Scene Analysis, Probabilistic Models, k Nearest Neighbor, neural Network,
Aspectos metodológicos en la medición del consumo de alcohol: la importancia de los patrones de consumo

Medir correctamente el consumo de alcohol es fundamental para investigar de forma fiable sus efectos en salud. Sin embargo, esta estimacion resulta enormemente compleja, tanto por la diversidad de formas de consumo de alcohol existente como por la gran heterogeneidad en su clasificacion. Ademas, cada patron de consumo de alcohol puede asociarse a efectos muy diferentes sobre la salud, por lo que no tenerlos en consideracion cuando estimamos la ingesta de alcohol puede ocultar o confundir su importancia en estos efectos. Todo ello dificulta las comparaciones entre estudios y el establecimiento de asociaciones consistentes que permitan comprender los verdaderos efectos del consumo de alcohol, tanto globales como especificos de cada patron de bebida. Este trabajo revisa los principales metodos y fuentes de informacion disponibles en Espana para estimar los aspectos mas relevantes del consumo de alcohol, asi como las dificultades y problemas metodologicos mas frecuentes en la medicion y clasificacion de cada uno de estos indicadores.
The Implications of Global English for Language Endangerment and Linguistic Identity: The Case of Arabic in the GCC States

Numerous sociolinguistic studies have been concerned with investigating the factors that pose challenges to the position of Arabic in the Arab Gulf countries including the demographic structure, migrant labor, bilingual education, and the unique diaglossic nature of Arabic. However, thus far, there has been no conceptual framework for addressing the implications of the increasing use of English for the position and future of Arabic in these countries. A number of studies concluded that English has superseded Gulf Arabic and dominated the linguistic identity of its native speakers without providing empirical evidence for such claims. In the face of this limitation, this study adopts a sociolinguistic framework using language planning and language policy (LPP) methods in order to investigate the effects and implications of the use of English as a global language and lingua franca in the Arab Gulf states and propose workable, reliable and effective language policies that can help in maintaining Arabic as the first language in the Gulf Cooperation Council (GCC) states and addressing problems of language endangerment and death. Results indicate that the disappearance of a language and the loss of its status cannot be solely attributed to the widespread of global English. Global English, on the contrary, should not be considered as a threat to the linguistic and national identity in the GCC countries. The real threat that Arabic faces is the failure to meet the increasing needs of its users and speakers which has its implications for the status and future of Arabic. It is suggested then that more descriptive approaches should be adopted in the analysis and teaching of Arabic. Linguistic changes of Arabic should be considered inevitable and not be resisted in order for Arabic to address the changing needs of its users. Arabic should also be more involved in today’s globalised world. Finally, the sense of linguistic identity should be promoted among citizens and students.
Symmetric Fluoroborate and its Boron Modification: Crystal and Electronic Structures

Four boron-carrying molecules were synthesized and purified. These were found to be (a) relatively neutral with respect to the parent BF derivative and (b) functionalized by donor–acceptor groups resulting in a charge transfer within the molecule. The study discusses the steric effect and the influence of the substitution of the side rings on the surroundings of the boron atom. Electronic structures were characterized by real-space bonding indicators. Hirshfeld surface and energy frameworks tools were applied to examine the crystal packing features.
The role of the National Botanic Garden of Namibia in plant species conservation

This study was aimed at determining and comparing plant species diversity, species composition and species richness in the National Botanic Garden and Aloe Trail areas in Windhoek, Namibia. Floristic data were collected following standard random plot sampling procedure, where 1m × 1m plots were nested in the 20m x 20m plots to measure herbaceous and woody plant species respectively. A total of 50 and 40 plots were sampled at the Botanic Garden and Aloe Trail areas respectively. The ShannonWiener diversity index was used to compute the species diversity of each plot sampled in each area. The Shapiro-Wilk test was used to test the data for normality. The Jaccard index of similarity revealed a 64% percentage similarity in species composition between the two sites. However, there was no significant difference in the herbaceous cover (Mann-Whitney statistic, Z = −1.314,p = 0.189) between the two areas. The Botanic Garden showed a significantly higher species richness than the Aloe Trail (ttest, p= 0.000). In addition, the Botanic Garden was found to be significantly more diverse (Mann-Whitney statistic, U=478, p=0.000) than the Aloe Trail because it is a protected area that is fenced and with minimal disturbances. The higher species diversity in the National Botanic Garden is attributable to the role of these living collections in the conservation of plant species.
Factors influencing student’s retention in secondary schools in armed conflict areas: a case of Mount Elgon district

The aim of the study was to investigate factors that influence retention of students in secondary schools in Mt. Elgon District because of the armed conflict that occurred in the area in the period 2006 to 2008. The objectives of the study were to establish effects of armed conflict on parental socio-economic factors that influence retention of students; find out the influence of armed conflict on school related factors that determine retention; determine effects of armed conflicts on school policies that influence retention. The theoretical framework of the study was based on the systems theory which assumes the concept that organizations are strongly influenced by their environment which exerts various forces of an economic, social or political nature. The research was a descriptive survey design. Multistage sampling was employed to cater for difference in geographical and school characteristics. Stratified sampling was used to select 16 secondary schools from a population of 25 schools in the district. Form three students in the selected schools were used because they had adequate experience about the variables under consideration. 27 class teachers that were teaching form three were purposively selected because they had privileged information about the students. Principals from the selected schools were also purposively selected because of their role as custodians of school records in total the study used 459 respondents. Data collection instruments namely; questionnaire, interview schedule was used. Descriptive and statistics were used to analyze the data collected. Findings indicate that the main parental socio-economic factors that influence retention was lack of food and poverty after destruction of property during the armed conflict. Inadequate number of teachers, lack of enough text books and lack of physical facilities are the school related factors that determine retention and were affected during the armed conflict. Guidance and counseling was the only school policy that was used to retain students in school during the conflict period. Recommendations were; provision of bursaries and financial support to the needy students, peace education in schools and provision of security in schools in the affected areas.
Formulation of Furosemide Oral Disintegrating Tablets Using Natural and Synthetic Superdisintegrants by SeDeM Expert Design System

SeDeM design expert technique used to evaluate the risks of poor flow of pharmaceutical powders under preformulation studies which reveals direct compression suitability and prepare robust composition of active pharmaceutical ingredient (API) and excipient in tablets formulation. The purpose of this study was to develop oral disintegrating tablets of Furosemide using different concentration of natural a nd synthetic superdisintegrants by means of SeDeM design technique. Oral disintegrating tablets (ODT) of Furosemide were prepared by direct compression technique using isolated banana powder and croscarmellose sodium (Ac-di-sol) together with microcrystalline cellulose as superdisintegrants. SeDeM design was performed to check suitability and deficient of excipients and drug for optimized composition derived based on IPP value. These tablets were evaluated for hardness, friability, drug content, weight variation, wetting time and in-vitro dissolution. All the formulations showed low weight variation with dispersion time less than 173.5±0.70 seconds and rapid in-vitro dissolution. The drug content of all the formulations was within the acceptable limits. Lubricated blend composition of F4 found average radius value 5.24, 0.66 and 5.509 for IGC, IP and IPP respectively, compressed tablet shown good physical properties. The optimized formulation F4 showed good release profile with 99.25 percentage drug release compared to other trial batches. It was concluded that natural superdisintegrant (banana powder) showed better disintegrating property than synthetic super disintegrant (Ac-di-sol) in the formulations of ODTs.
PHARMACOGENOMICS - A NEW PERSPECTIVE IN CLINICAL HEALTHCARE

The post-genome era has heralded the beginning of incorporating genome-wide approaches in processes beginning from drug discovery to clinical prescription with the ultimate aim of viewing modern medicine as personalized molecular medicine. A pioneering step in this direction is the development of Pharmacogenomics – the study of the interplay of genotype and drug efficacy that seeks to identify the variant genes affecting the response to drugs in individual patients. These variations can be used to predict whether a patient will have a good response to a drug, a bad response to a drug, or no response at all. Pharmacogenomic studies encompass the sum of all genes, i.e., the genome with respect to its its impact on pharmacokinetics and pharmacodynamics. Initially termed as Pharmacogenetics, it is now synonymous with Pharmacogenomics. A classical example cited in literature is the existence of a polymorphism in the metabolism of the antituberculous drug – Isoniazid (INH) that affects the catalytic activity of the acetylating enzyme, thus leading to slow acetylation of INH. Certain populations of the world are associated with this polymorphism making them slow acetylators. Similar polymorphisms have also now been studied in many other genes of pharmacogenomic significance. The use of non-automated and automated methods for profiling genotypes has tremendously helped to reveal the
Performance of Friction Piled Raft with Cement Deep Mixing Walls in Soft Ground During the 2011 East Japan Earthquake

The static and seismic behaviour of a friction piled raft foundation, supporting a seven-storey building, is investigated by monitoring the soil-foundation-structure system over eleven years from the beginning of the construction. Since the building is constructed on liquefiable sandy soil, underlain by very soft clayey soil, grid-form cement deep mixing walls (DMWs) were employed as a countermeasure of liquefaction with the piled raft. At the time of the 2011 East Japan earthquake, the seismic response of the soil-foundation system was successfully recorded. Although small changes in the foundation settlement and the load sharing between the raft and the piles were observed after the earthquake, it was confirmed that the friction piled raft with the gridform DMWs showed a good performance in the soft ground.
Private sector participation in the Farm Input Subsidy Programme in Malawi.

The Farm Input Subsidy Programme (FISP) in Malawi has been implemented since the 2005/06 season with the objective of improving household and national food production and incomes. It targets more than 1.5 million farm families who receive subsidised fertilisers, improved maize seeds and/or legume seeds. The implementation of the FISP has involved the interaction of the Government of Malawi, the private sector, development partners, civil society organisations (CSOs), non-governmental organisations (NGOs), traditional leaders and smallholder farmers, all playing different roles in the implementation and success of the programme. The private sector has played a critical role, but its involvement in the programme has changed over time. This has included the procurement of fertilisers, the transportation of fertilisers to various markets, the retail sale of fertilisers, and the production and sale of improved seeds.
Effect of Water Extracts of some Aromatic and Medicinal Plants on Mortality and Egg Hatching of Root- knot Nematode, Meloidogyne Incognita in Vitro studies

Water extracts of the ten aromatic and medicinal plant namely, Camphor (Eucalyptus globulus), Camphor Lemon (E. citriodora), Demssisa (Ambrosia maritime), Lemon grass (Cymbopgon citratus), Marjoram (Origamum majorana), Neem (Azadrachta indica), Rosemary (Rosmarimus officinallis) and Thyme (Thymus vulgaris) as leaves, Chamomile (Matricaria chamomilla) and Daisy (Calendula officinalis) as leaves and flowers with different concentrations (5, 10 & 15%) of different plants were assessed in vitro against egg hatching and juveniles (J2s) mortality of rootknot nematodes Meloidogyne incognita in different durations. Results indicated that eggs inhibition and J2s mortality increased with an increase in the concentration of all the extracts. Similarly, with an increase in exposure time, J2s mortality was also increased. Water extracts of all plants showed nematicidal effect against M. incognita at varying degree. Based on these finding, these plant extracts at the highest concentration (15%) were divided into 4 main groups i.e. highly toxic ( 85% mortality or inhibition), consisting of Demssisa, Camphor Lemon and Thyme, toxic (70 < 85%) consisting of Daisy and Marjoram, moderately and lowly toxic groups, consisting of the test plant extracts tested. This finding is important from the point of view of controlling rootknot nematodes without the use of chemical nematicides in view of environmental pollution likely to cause. The use of these plant extracts may be one of the efficient alternatives and cheep methods of nematode control, that are sale to farmers and inurnment. These may be replacement to the synthetic dangerous and expensive chemical nematicides in future.
Does the hype surrounding FinTechs lead to an overvaluation of their stock prices ?

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