Miracle-dz/UniFAR-FTUs huggingface dataset:
Supporting the design of useful and relevant holistic frameworks for land use opportunity assessment for indigenous people

ABSTRACT Choices about how to use land are critical to efforts to manage water quality in Aotearoa-New Zealand. Māori and non-Māori communities need decision-making frameworks that enable their values and priorities to inform land use choices. However, few of the available frameworks meet the needs of Māori communities. It is challenging to construct decision-making frameworks that have true utility for both Māori and non-Māori land stewards because of differences in their relationships with the whenua (land), the wai (the water) and te taiao (the environment). Additionally, Māori may utilise different types and formats of data in their decision-making from those traditionally encompassed by science-based frameworks. This paper aims to help non-indigenous researchers understand the required development processes and design features if a framework aimed at a broad audience is to have genuine relevance and utility for indigenous users. To achieve this, we utilised a modified version of Cash et al.’s Credibility, Salience and Legitimacy framework to evaluate a range of land use decision-making frameworks. We discuss why science-based concepts of holism are not the same as those embodied by a Māori worldview. We conclude that it is essential to co-develop frameworks in genuine partnership with Māori.
Perception on Usability and Risk of E-Business Platform for Women Managed Small and Medium Weaving Enterprises

Rapid technological advances in information and communication technology have resulted in distance no longer a major problem in conducting business activities. Every individual and business actor is also carried away by the flow of having tools that can support their daily activities have been parts of the existence of technology. This study analyzes the effect of usability and risk perception in small and medium weaving enterprises (SMWE), which women manage, in using e-business, e.g., online shops, e-commerce, and marketplaces. We surveyed 43 SMWEs using questionnaires and interviews and selected the samples using the saturated sampling technique. Quantitative data was collected through a Likert scale and then analyzed using multiple linear regression. The study results show that usability positively affects the interest in using e-business in SMWEs. Meanwhile, the risk perception variable has a negative and significant direction. Usability makes it easier for individuals to understand and easy to get information in using e-business. The use of information systems can speed up work and provide flexibility in convenience. The risks faced by e-business users are transaction security and the uncertainty of the goods ordered. Perceived risk will hurt the individual’s intention to use the online store. This prediction arises based on logic if the higher risk on online transactions lacks necessary trust.
Three dimensional free vibration analysis of functionally graded graphene reinforced composite laminated cylindrical panel

In this paper, natural frequency analysis of functionally graded graphene platelet (GPL) reinforced composite cylindrical panel is investigated. Halpin-Tsai equations are employed to obtain the mechanical properties of the structure. The linear three-dimensional elasticity theory based on the Hamilton principle and the numerical finite element method are used for obtaining the governing equations of motion. Four patterns of GPL distributions such as: FG-X, FG-V, FG-O and UD are assumed through the thickness of shell. The effects of various parameters such as different distributions and weight fractions of GPL, zigzag and armchair lay-up, geometry and different boundary conditions on the natural frequencies and mode shapes of shell have been investigated. The results indicate that the maximum and minimum natural frequencies belong to FG-X pattern and FG-O pattern, respectively.
Social networks and local communication network patterns following the destructive 2018 Lombok, Indonesia, earthquake sequence

Abstract Social communication networks created during the 2018 earthquake sequence in Lombok, Indonesia using social network data from a social media platform, i.e., Facebook, and surveys in local communities were analyzed. The different modes of communication networks used during the disaster event and post-disaster mitigation were examined. Data on social media platform usage were collected from the Facebook page of the Agency for Meteorology, Climatology and Geophysics of Indonesia and the National Board for Disaster Management of Indonesia. The data show large clusters of social relation networks based on dominant issues discussed by the public under several trending hashtags. Meanwhile, the local patterns of social communication networks, particularly the flow of information and communication used by the local communities of the impacted villages in Lombok, differ depending on the culture of communication and time of accessing information. During the 2018 Lombok earthquake sequence, communication was predominantly sought from community leaders, religious leaders, family members, and neighbours. This study highlights the implementation of a decentralization system in Indonesia, which has given the local and regional authorities a significant role in disaster management, response, and emergency command for the local and regional community, instead of relying largely on the response of the central Jakarta government.
BIRC5 promotes cancer progression and predicts prognosis in laryngeal squamous cell carcinoma

Background Laryngeal squamous cell carcinoma (LSCC) remains one of the most common respiratory tumors worldwide. Baculoviral inhibitor of apoptosis repeat containing 5 (BIRC5) is a member of the inhibitor-of-apoptosis protein family. BIRC5 plays an important role in various types of cell proliferation, differentiation, migration and invasion. However, the specific role of BIRC5 in LSCC remains unclear. Methods To provide a prognostic biomarker for LSCC, we screened the prognostic genes of LSCC via bioinformatics. PPI network and KEGG pathways were used to select hub genes. Clinical prognoses were performed using a Kaplan–Meier plotter and Cox proportional-hazard analysis. BIRC5 expression in LSCC tissues and cell lines were detected by RT-PCR, Western blot and Immunohistochemistry (IHC). Cell proliferation, cell cycle and cell apoptosis were detected with Cell Counting Kit-8 (CCK-8) and Flow Cytometry assay, respectively. Results Here, BIRC5 was strongly correlated with higher tumor grade and differentiation. BIRC5 was highly expressed in LSCC tissues when compared with normal tissues and increased expression of BIRC5 was associated with overall survival in LSCC patients. The suppression of BIRC5 induced cell apoptosis and cell cycle arrest, thereby inhibiting the proliferation of LSCC cells. The survival analysis confirmed that higher level of BIRC5 expression predicted poor prognosis of LSCC patients. BIRC5 may act as an oncogene of LSCC development and was suggested as a promising prognostic biomarker for LSCC.
The declining appeal of mega-events in entrepreneurial cities: From Los Angeles 1984 to Los Angeles 2028

Mega-events appear to be losing their appeal as tools for urban development. Events have long been funded by local governments on the promise that they can act as a catalyst for economic growth. But constituents and leaders are questioning that approach, disrupting the relationship between municipalities and global sports institutions. These political shifts are analyzed with a comparative study of Olympic planning and urban politics in American cities, from the Los Angeles 1984 Olympics to present-day preparations for the Los Angeles 2028 Olympics (during this period, Olympic planning also occurred in Atlanta, Boston, Chicago, Los Angeles, New York, and Salt Lake City). The paper examines the development, mobility, and contestation of an “LA model” of mega-event planning, which emphasizes municipal fiscal conservativism, and which has provided a political rationale for city leaders to invest in mega-events. The travels of the model illustrate the evolving role of mega-events in the political economy of entrepreneurial cities.
Structure motif of chemical short-range order in a medium-entropy alloy

The chemical short-range orders (CSRO) are the sub-nanosized entities inherent in high-/medium-entropy alloys (H/MEA). To discern CSRO poses the challenge with pending issues as to under what zone axis in electron diffraction, signature scattering specific to CSRO will appear and what the structure motif of CSRO is. Here, we show extra diffuse scattering by CSRO from [111] and [112] directions in a VCoNi MEA and accordingly, construct the -type structure motif, and derive the spacial shape of flat cuboid of CSRO in virtue of diffractions under varying zone axis. Moreover, we demonstrate the methods to identify CSRO in lattice images. GRAPHICAL ABSTRACT IMPACT STATEMENT The structure motif is constructed as -type for chemical short-range order in a medium-entropy alloy in terms of electron diffractions under the multiple zone axis.
In Vitro Assessment of Antistaphylococci, Antitumor, Immunological and Structural Characterization of Acidic Bioactive Exopolysaccharides from Marine Bacillus cereus Isolated from Saudi Arabia

A strain of Bacillus cereus was isolated from the Saudi Red Sea coast and identified based on culture features, biochemical characteristics, and phylogenetic analysis of 16S rRNA sequences. EPSR3 was a major fraction of exopolysaccharides (EPS) containing no sulfate and had uronic acid (28.7%). The monosaccharide composition of these fractions is composed of glucose, galacturonic acid, and arabinose with a molar ratio of 2.0: 0.8: 1.0, respectively. EPSR3 was subjected to antioxidant, antitumor, and anti-inflammatory activities. The results revealed that the whole antioxidant activity was 90.4 ± 1.6% at 1500 µg/mL after 120 min. So, the IC50 value against DPPH radical found about 500 µg/mL after 60 min. While using H2O2, the scavenging activity was 75.1 ± 1.9% at 1500 µg/mL after 60 min. The IC50 value against H2O2 radical found about 1500 µg/mL after 15 min. EPSR3 anticytotoxic effect on the proliferation of (Bladder carcinoma cell line) (T-24), (human breast carcinoma cell line) (MCF-7), and (human prostate carcinoma cell line) (PC-3) cells. The calculated IC50 for cell line T-24 was 121 ± 4.1 µg/mL, while the IC50 for cell line MCF-7 was 55.7 ± 2.3 µg/mL, and PC-3 was 61.4 ± 2.6 µg/mL. Anti-inflammatory activity was determined for EPSR3 using different methods as Lipoxygenase (LOX) inhibitory assay gave IC50 12.9 ± 1.3 µg/mL. While cyclooxygenase (COX-2) inhibitory test showed 29.6 ± 0.89 µg /mL. EPSR3 showed potent inhibitory activity against methicillin-resistant Staphylococcus aureus (MRSA) and coagulase-negative staphylococci. The exposure times of EPSR3 for the complete inhibition of cell viability of methicillin resistant S. aureus was found to be 5% at 60 min. Membrane stabilization inhibitory gave 35.4 ± 0.67 µg/mL. EPSR3 has antitumor activity with a reasonable margin of safety. The antitumor activity of EPSR3 may be attributed to its content from uronic acids with potential for cellular antioxidant and anticancer functional properties.
Three General Determinants of Support-Systems

Different research institutes and companies are developing technical systems to support or assist people at work and in daily life. The technical systems can be used for a wide range of different applications. Moreover, the systems have different forms with respect to their application. This paper will analyse and classify different forms of such systems in a general manner. The classification procedure will be illustrated by exemplary solutions.
Performance of the Digital Dietary Assessment Tool MyFoodRepo

Digital dietary assessment devices could help overcome the limitations of traditional tools to assess dietary intake in clinical and/or epidemiological studies. We evaluated the accuracy of the automated dietary app MyFoodRepo (MFR) against controlled reference values from weighted food diaries (WFD). MFR’s capability to identify, classify and analyze the content of 189 different records was assessed using Cohen and uniform kappa coefficients and linear regressions. MFR identified 98.0% ± 1.5 of all edible components and was not affected by increasing numbers of ingredients. Linear regression analysis showed wide limits of agreement between MFR and WFD methods to estimate energy, carbohydrates, fat, proteins, fiber and alcohol contents of all records and a constant overestimation of proteins, likely reflecting the overestimation of portion sizes for meat, fish and seafood. The MFR mean portion size error was 9.2% ± 48.1 with individual errors ranging between −88.5% and +242.5% compared to true values. Beverages were impacted by the app’s difficulty in correctly identifying the nature of liquids (41.9% ± 17.7 of composed beverages correctly classified). Fair estimations of portion size by MFR, along with its strong segmentation and classification capabilities, resulted in a generally good agreement between MFR and WFD which would be suited for the identification of dietary patterns, eating habits and regime types.
Mesoporous silica nanoparticles: Synthesis, functionalization, drug loading and release - A review

A brief survey on the synthesis of several types of mesoporous silica nanoparticles and their uses as drug delivery nanocarriers is presented in this study. Mesoporous silica nanoparticles (MSNs) have a small pore size, resulting in a large surface area and porosity. These characteristics are easily adjustable, conferring on MSNs advantages over other nanoparticles for use in medicine and pharmacy. Previous and latest trends in the technology of this type of nanoparticles, and the possibilities for their application in drug loading are considered, as well as methods for increasing drug loading capacity, functionalization and release of bioactive substances. It has been found that the method used for the synthesis of some types of MSNs results in better drug loading. The functionalization of nanoparticles not only allows for more successful loading of bioactive substances in its pores, it also successfully controls drug release. Moreover, these versatile nanoparticles enhance the solubility of poorly-soluble drugs, thereby overcoming one of the biggest problems in the absorption of these drugs.
Evaluation of impact of pharmaceutical care services on cardiologist adherence to hypertension Guidelines JNC 7: A critical prospect for rational use of drugs in Pakistan

Purpose: To assess the adherence of cardiologists to JNC7 and the impact of pharmacists in reducing clinical inertia by managing high blood pressure in the cardiology out-patient department of the Armed Forces Institute of Cardiology, Rawalpindi, Pakistan. Methods: This was a pre- and post-interventional prospective study in which data was abstracted from patients’ history notes or prescription of selected patients at baseline and follow-up visits by applying a reliable tool. The data were abstracted again from the same patients to evaluate the cardiologists’ adherence with the same parameters after 2,4 and 6 months. The sample size for this study was 116 patients and descriptive statistics were used for categorical variables. For the comparison of cardiologist’s adherence to JNC7, means and paired ‘t’ test were used at the level of 0.05 significance. Results: At baseline, the mean overall percentage of cardiologists’ adherence to JNC7 was 46.7 ± 18.9 %. This significantly improved to 98.8 ± 6.0 % after 2 months of the pharmacist intervening by way of discussions with cardiologists. The cardiologists’ adherence was further improved to 100 % after 4 and 6 months. Conclusion: Improvement in cardiologists’ adherence to JNC 7 guidelines and involvement of the pharmacist enhance the documentation of BP goal, lifestyle modifications and uncontrolled BP. All these helps to overcome clinical inertia that ultimately leads to better BP control and rational use of medicines.
Beyond barriers: the fluid roles young people adopt in water conflict and cooperation

ABSTRACT Most people on this planet are under the age of 35. They have been raising their voices in discussions on climate change in recent years, while this is well documented, their roles in water cooperation are not. Drawing on examples from desk research, an online survey, and action research alongside young water leaders, this article seeks to map out various ways young people engage in water conflict and cooperation. This paper contributes to literature on water leadership by recognizing the fluid and adaptive roles of young people in water conflict and cooperation.
An Assessment of the Net Fluid Balance in the Alberta Basin

Net fluid balance in the Alberta Basin has been negative over the last 60 years because extensive fluid production has consistently exceeded injection during this period. However, future gigaton-scale carbon sequestration, among other activities, can result in future cumulative fluid injection exceeding extraction (i.e., a positive net fluid balance). The in-situ net fluid balance (i.e., total fluids produced minus total fluids injected) in this basin over the period 1960–2020 shows that a liquids deficit of 4.53x109 m3 and a gas deficit of 6.05x1012 m3 currently exist. However, fluid deficits are more significant in the upper stratigraphic intervals (located more than 1 km above the Precambrian Basement) than in the stratigraphic intervals located within 1 km of the Precambrian Basement in most geographic regions. This observation indicates that greater sustainable injection capacity for large-scale fluid injection may exist in the upper stratigraphic intervals (located at more than 1 km above the Precambrian Basement), reducing the potential for generating induced seismicity of concern. Additionally, while fluid depletion rates consistently increased over most of the last 60 years in the Alberta Basin, this trend appears to have changed over the past few years. Such analysis of regional net fluid balance and trends may be useful in assessing regional sustainable fluid storage capacity and managing induced seismicity hazards.
Role of cardiopulmonary exercise test in the prediction of hemodynamic impairment in patients with pulmonary arterial hypertension

Abstract Periodic repetition of right heart catheterization (RHC) in pulmonary arterial hypertension (PAH) can be challenging. We evaluated the correlation between RHC and cardiopulmonary exercise test (CPET) aiming at CPET use as a potential noninvasive tool for hemodynamic burden evaluation. One hundred and forty‐four retrospective PAH patients who had performed CPET and RHC within 2 months were enrolled. The following analyses were performed: (a) CPET parameters in hemodynamic variables tertiles; (b) position of hemodynamic parameters in the peak end‐tidal carbon dioxide pressure (PETCO2) versus ventilation/carbon dioxide output (VE/VCO2) slope scatterplot, which is a specific hallmark of exercise respiratory abnormalities in PAH; (c) association between CPET and a hemodynamic burden score developed including mean pulmonary arterial pressure (mPAP), pulmonary vascular resistance (PVR), cardiac index, and right atrial pressure. VE/VCO2 slope and peak PETCO2 significantly varied in mPAP and PVR tertiles, while peak oxygen uptake (peak VO2) and O2 pulse varied in the tertiles of all hemodynamic parameters. PETCO2 versus VE/VCO2 slope showed a strong hyperbolic relationship (R 2 = 0.7627). Patients with peak PETCO2 > median (26 mmHg) and VE/VCO2 slope < median (44) presented lower mPAP and PVR (p < 0.005) than patients with peak PETCO2 < median and VE/VCO2 slope > median. Multivariate analysis individuated peak VO2 (p = 0.0158) and peak PETCO2 (p = 0.0089) as hemodynamic score independent predictors; the formula 11.584 − 0.0925 × peak VO2 − 0.0811 × peak PETCO2 best predicts the hemodynamic score value from CPET data. A significant correlation was found between estimated and calculated scores (p < 0.0001), with a precise match for patients with mild‐to‐moderate hemodynamic burden (76% of cases). The results of the present study suggest that CPET could allow to estimate the hemodynamic burden in PAH patients.
Testing the Job Demands-Resources Model with Organizational Trust among Prison Staff

Trust is an essential component of effective organizations and may be especially important in corrections because of the unique challenges this work environment presents. In corrections, trust in both supervisors and the administration is critical to ensuring the safety and security of staff, inmates, and the community. Previous research has revealed important implications of organizational trust, but less is known about the workplace factors that shape organizational trust. Scholars have divided these workplace factors into job demands and job resources. Using data from 322 correctional staff (both custodial and non-custodial staff) working at a large prison in the Southern United States, this study tested the job demands-resources model on two types of organizational trust – supervisor trust and administration trust. Specifically, we examined three job demands – role ambiguity, fear of being victimized at work, and role overload – and three job resources – job variety, quality training, and autonomy. Ordinary Least Squares regression results showed that workplace variables predicted both types of organizational trust and were generally stronger predictors than were personal attributes. Moreover, job resources played a greater role than job demands in shaping both supervisor and administration trust.
Modulated structure of hemimorphite associated with pressure–induced phase transition

In situ high – pressure single – crystal X – ray di ﬀ raction experiments on natural hemimorphite, ideally Zn 4 [Si 2 O 7 ](OH) 2 ·H 2 O, up to 4.7 GPa were conducted to investigate its pressure response property associated with pressure – induced phase transition. After the phase transition con ﬁ rmed between 2.46 and 3.01 GPa, pairs of satellite re ﬂ ections were newly found at certain Bragg re ﬂ ections. The modulation vector q of the satellites was approximately [0, 1/8.4, 0]. The results of the re ﬁ nements on the averaged structure indicated that the modulation arose from displacements of atomic sites associated with the mechanism of the phase transition, i.e., the rotation of the secondary building unit (SBU). The lower rotation angle of the SBU ( Φ ) than the value estimated from the non – modulated structure meant that the high – pressure phase contained anti – phase boundaries (APBs) resulting from the opposite direction of the SBU rotation and that the coherency was held across the APBs. Within the coherent domain, the APB ’ s intervals were distributed along the b – axis with a mean value of 8.4 b ≈ 90 Å, where the displacement of each site η ( y ) was approximated as the ﬁ rst – harmonic. The distribution of the direction of SBU rotation was initially considered to be inhomogeneous, but the elimination of the APBs had proceeded anisotropically and had been aborted below 3.01 GPa.