Miracle-dz/UniFAR-FTUs huggingface dataset:
Protective Effect of Lycium ruthenicum Polyphenols on Oxidative Stress against Acrylamide Induced Liver Injury in Rats

Acrylamide (ACR) is formed during tobacco and carbohydrate-rich food heating and is widely applied in many industries, with a range of toxic effects. The antioxidant properties of Lycium ruthenicum polyphenols (LRP) have been established before. This study aimed to research the protective effect of LRP against ACR-induced liver injury in SD rats. Rats were divided into six groups: Control, ACR (40 mg/kg/day, i.g.), LRP (50, 100, and 200 mg/kg/day, i.g.) plus ACR, and LRP groups. After 19 days, we evaluated oxidative status and mitochondrial functions in the rat’s liver. The results showed that glutathione (GSH) and superoxide dismutase (SOD) levels increased after LRP pretreatment. In contrast, each intervention group reduced reactive oxygen species (ROS) and malondialdehyde (MDA) levels compared to the ACR group. Meanwhile, alanine aminotransferase (ALT), aspartate aminotransferase (AST), liver mitochondrial ATPase activity, mRNA expression of mitochondrial complex I, III, and expression of nuclear factor-erythroid 2-related factor 2 (Nrf2) and its downstream proteins were all increased. This study suggested that LRP could reduce ACR-induced liver injury through potent antioxidant activity. LRP is recommended as oxidative stress reliever against hepatotoxicity.
Design of Synchronous PM Motor for Submersed Marine Propulsion Systems

The high power permanent magnet (PM) motors are suitable for submersed marine propulsion systems combining the advantages of high energy density magnets and electronic drives. In particular the electrical power management realises :  higher ship manoeuvrability  low fuel consumption  reduced maintenance costs  exhaust emissions limitation  adequate redundancy with less installed power  noise and vibration reduction  higher availability of components Thus the electrical propulsion system competes successfully with the traditional mechanical systems. The commercial marine market areas emerging for importance are two. At the moment they are covered by two different propulsive solutions:
Analysis of Digital Leadership in School Management and Accessibility of Animation-Designed Game-Based Learning for Sustainability of Education for Children with Special Needs

With the rapid integration of technology into educational environments during the pandemic period, the teaching processes in classrooms and private education institutions began to be carried out with technology support. Game-based animation learning designs in technology-supported educational environments provide an interesting and motivation-enhancing learning experience in developing students’ education skills. In today’s educational environments, 2D and 3D animation game designs are the unique technology-supported learning environments in teaching many different skills, behaviors, and concepts to individuals with special needs. Visual designs and animations are one of the technologies necessary to prepare individuals with special needs for an independent life. The accessibility of animation designs for teachers and families has gained significant importance during the COVID-19 pandemic period. Technology education supports the visual, listening, reading, writing, social, and communication skills of individuals with special needs, facilitates their independent life skills, and contributes to their development as a guide. This allows individuals to learn the targeted information more easily, permanently, and quickly. In this context, this study provides information on the use and accessibility of animation technology in special education, offers suggestions for the benefit of visual design and animation, which are among the assistive technologies, and gives insights into how school management is ready for digital education.
A Case of Plant Vaccination: Enhancement of Plant Immunity against Verticillium dahliae by Necrotized Spores of the Pathogen

The soil-borne fungus Verticillium dahliae is causing a devastating vascular disease in more than 200 species of dicotyledonous plants. The pathogen attacks susceptible plants through the roots, colonizes the plant vascular system, and causes the death of aerial tissues. In this study, we used Arabidopsis and eggplants to examine the plant protective and immunization effects of autoclaved V. dahliae spores against V. dahliae. We observed that the application of V. dahliae autoclaved spores in eggplants and Arabidopsis resulted in enhanced protection against V. dahliae, since the disease severity and pathogen colonization were lower in the plants treated with V. dahliae autoclaved spores when compared to controls. In addition, upregulation of the defense related genes PR1 and PDF1.2 in the Arabidopsis plants treated with the V. dahliae autoclaved spores was revealed. Furthermore, pathogenicity experiments in the Arabidopsis mutant cerk1, defective in chitin perception, revealed a loss of protection against V. dahliae in the cerk1 treated with the V. dahliae autoclaved spores. The participation of the chitin receptor CERK1 is evident in Arabidopsis immunization against V. dahliae using autoclaved spores of the pathogen.
Assessment of biochemical and physiological tolerance mechanism of the multipurpose paradise tree (Simarouba amara Aubl.) under zinc and copper stress

Simarouba amara Aubl. , commonly known as paradise tree, is a multipurpose, evergreen, poly-gamodioecious, and oil yielding tree. The plant is famous for its seeds containing 55-65% oil, a potent source of biodiesel production and is being utilized in cosmetics, pharmaceuticals, and other industries. The study aimed to evaluate the physiological and biochemical changes that occur in S. amara seedlings under heavy metals stress. Two-month-old S. amara seedlings were exposed to different concentrations of zinc (Zn) and copper (Cu) (Zn and Cu: 10 mg Kg-1, 50 mg Kg-1, 100 mg Kg-1, 200 mg Kg-1). The study indicated that both the heavy metals resulted in a significant decrease in leaf relative water content (LRWC), photosynthetic pigments and an increase in lipid peroxidation and antioxidant levels. Regarding lipid peroxidation, Cu proved to be more toxic to seedlings compared to Zn. However, in terms of LRWC and photosynthetic pigments, Zn showed higher toxic effects than Cu. Proline and cysteine content increased by 234% and 270%, respectively, due to Zn stress and 117% and 102%, respectively, due to Cu stress at 200 mg Kg-1. Among antioxidant enzymes, a maximum increase in glutathione reductase (GR) activity was observed (600% due to Cu stress and 320% due to Zn stress) at 200 mg Kg-1. At the same concentration, a minimum increase was seen in glutathione peroxidase (GPX) activity (60% under Cu stress) and catalase (CAT) activity (69% under Zn stress). The present study revealed that S. amara has a better antioxidant defensive mechanism against oxidative stress and can be used for its large scale cultivation on wastelands.
High-Ability Students’ Need Satisfaction and Motivation in Pull-Out and Regular Classes: A Quantitative and Qualitative Comparison Between Settings

ABSTRACT In this two-part study, high-ability students’ experiences of need support, need satisfaction, and motivation in regular and pull-out classes were compared. Quantitative results from Study 1 indicated that high-ability students (N = 203) reported more satisfaction of their needs for autonomy, competence, and relatedness and more favorable motivational outcomes in their pull-out class compared to their regular class. In both settings, need satisfaction predicted high-ability students’ motivational outcomes. These findings could be explained by the qualitative findings from Study 2 which indicated that high-ability students (N = 11) experienced pull-out class teachers as more supportive of their needs than their regular class teachers. Overall, findings suggest that need-supportive teaching is an effective strategy to foster high-ability students’ motivation in both regular classes as well as pull-out classes.
On the Performance of a Wave Power Converter

This paper presents the KN-principle for wave - power conversion. The principle and components of the wave power converter are described and some practical relations are presented in order to calculate the power absorbed by the wave power converter in irregular sea states. The performance of a scale model has been tested at sea. Experimental results and practical experience gained through the sea trail are presented.
AlGaAs Nonlinear Integrated Photonics

Practical applications implementing integrated photonic circuits can benefit from nonlinear optical functionalities such as wavelength conversion, all-optical signal processing, and frequency-comb generation, among others. Numerous nonlinear waveguide platforms have been explored for these roles; the group of materials capable of combining both passive and active functionalities monolithically on the same chip is III–V semiconductors. AlGaAs is the most studied III–V nonlinear waveguide platform to date; it exhibits both second- and third-order optical nonlinearity and can be used for a wide range of integrated nonlinear photonic devices. In this review, we conduct an extensive overview of various AlGaAs nonlinear waveguide platforms and geometries, their nonlinear optical performances, as well as the measured values and wavelength dependencies of their effective nonlinear coefficients. Furthermore, we highlight the state-of-the-art achievements in the field, among which are efficient tunable wavelength converters, on-chip frequency-comb generation, and ultra-broadband on-chip supercontinuum generation. Moreover, we overview the applications in development where AlGaAs nonlinear functional devices aspire to be the game-changers. Among such applications, there is all-optical signal processing in optical communication networks and integrated quantum photonic circuits.
Nedd4-2 Haploinsufficiency in Mice Impairs the Ubiquitination of Rer1 and Increases the Susceptibility to Endoplasmic Reticulum Stress and Seizures

Neural precursor cell expressed developmentally downregulated gene 4-like (NEDD4-2) is an epilepsy-associated gene encoding an E3 ligase that ubiquitinates neuroactive substrates. An involvement of NEDD4-2 in endoplasmic reticulum (ER) stress has been recently found with mechanisms needing further investigations. Herein, Nedd4-2+/− mice were found intolerant to thapsigargin (Tg) to develop ER stress in the brain. Pretreatment of Tg aggravated the pentylenetetrazole (PTZ)-induced seizures. Retention in endoplasmic reticulum 1 (Rer1), an ER retrieval receptor, was upregulated through impaired ubiquitination in Nedd4-2+/− mouse brain. Nedd4-2 interacted with Rer1 more strongly in mice with Tg administration. The negative regulation and NEDD4-2-mediated ubiquitination on RER1 were evaluated in cultured neurocytes and gliacytes by NEDD4-2 knockdown and overexpression. NEDD4-2 interacted with RER1 at higher levels in the cells with Tg treatment. Disruption of the 36STPY39 motif of RER1 attenuated the interaction with NEDD4-2, and the ubiquitinated RER1 underwent proteasomal degradation. Furthermore, the interactome of Rer1 was screened by immunoprecipitation-mass spectrometry in PTZ-induced mouse hippocampus, showing multiple potential ER retrieval cargoes that mediate neuroexcitability. The α1 subunit of the GABAA receptor was validated to interact with Rer1 and retain in ER more heavily in Nedd4-2+/− mouse brain by Endo-H digestion. In conclusion, Nedd4-2 deficiency in mice showed impaired ubiquitination of Rer1 and increased ER stress and seizures. These data indicate a protective effect of NEDD4-2 in ER stress and seizures possibly via RER1. We also provided potential ER retention cargoes of Rer1 awaiting further investigation.
The effect of cadmium on growth and antioxidant responses in the safflower (Carthamus tinctorius L.) callus

: Saffl ower ( Carthamus tinctorius L.) callus cultures grown in the presence of diff erent concentrations (0-100 μM) of cadmium were assayed for growth, Cd accumulations, and antioxidative responses. Cadmium inhibited the growth of calli by 25% and 46% at 75 and 100 μM Cd concentrations, respectively. Cadmium concentration in the calli increased with an increased Cd supply in the growth medium. Calli accumulated 334 mg Cd kg–1 of their dry weight at 100 μM Cd. Cadmium induced oxidative stress, which was indicated by modulating antioxidant (glutathione and α-tocopherol) levels and antioxidative enzymes. Th e eff ect of Cd on glutathione (GSH) was dose-dependent. Th e GSH content increased up to a concentration of 75 μM Cd and then decreased. Levels of α-tocopherol showed a signifi cant increase with the increase in concentrations of Cd in the media. Antioxidant enzyme activity increased signifi cantly up to a concentration of 75 μM Cd. Concentrations of Cd greater than 75 μM resulted in a decline in antioxidant enzyme activity. Increased antioxidant levels and antioxidant enzyme activity in Cd-treated calli indicate that Cd detoxifi cation and accumulation in the saffl ower callus might be associated with the effi ciency of these mechanisms.
Purchasing products with sustainable palm oil: designing and evaluating an online intervention for Australian consumers

Abstract Widespread tropical deforestation and biodiversity loss in Southeast Asia due to the oil palm industry can be addressed by encouraging consumers to purchase sustainable palm oil (SPO). An online experiment was conducted to assess whether addressing barriers relating to education, motivation and product availability would increase purchasing of SPO. Australian adults (n = 628) were randomly assigned to either: (1) a newly developed interactive educational website on palm oil and SPO; (2) an existing educational video on SPO; or (3) an interactive website on differentiating between real and fake news (an attentional control condition). All participants completed pre-intervention and immediate post-intervention measures. Most participants (n = 403) completed follow-up measures two weeks later. Multivariate analysis revealed that the interactive website and educational video increased both knowledge and the intention to purchase SPO (compared to the attentional control), but neither significantly impacted follow-up self-reported SPO purchasing behaviour. Low perceived product availability might help explain the intention–behaviour gap. Our results suggest that, in addition to increasing consumer knowledge and motivation, promoting sustainable consumption requires creating opportunities for people to engage in the desired behaviour.
The effect of undulations on the particle stress in dilute suspensions of rod-like particles

Abstract We compared a dilute suspension of undulating rod-like particles (active suspension) with a similar one consisting of rigid rods (passive suspension) under shear flow. For the active suspension, a synchronised group of swimmers propel themselves forward by passing a travelling wave through their bodies while at the same time rotate due to planar background shear flow. Using a high resolution immersed body numerical simulations, we have shown that an active particle can exhibit complex dynamics, which is fundamentally different from a similar passive one. The orientation of the active particle consists of two separate oscillations: a low-frequency oscillation similar to the passive particle (determined by shear rate) and a high-frequency oscillation due to the body undulations. Nevertheless, different dynamics did not result in a major difference in rheological behaviour of the suspension. We found that the effective viscosity of the active suspension is equal to that of a passive one, i.e. self-propulsion did not change the viscosity of the suspension probably because of the high shear rate and inertia of our simulations.
Solar Wind Speed Prediction via Graph Attention Network

The solar wind is a plasma flow formed by the expansion of the high‐temperature corona and propagates in the interplanetary space with speeds between 200 km/s and 900 km/s. Accurate solar wind speed prediction and longer lead time will help mitigate the impact of solar storms on aerospace equipment and the Earth's magnetic field. Recently, most approaches do not explicitly capture the relationships between different solar wind features, and the prediction accuracy of 96‐hr is still not good enough. This paper elaborately designs an end‐to‐end model: Graph‐Temporal‐AR model (GTA) for solar wind speed prediction. First, our framework considers each feature as the node to construct the graph structure and adopts the graph attention module to learn the complex dependencies among features. Second, our approach employs the dilated causal convolution to extend the receptive field and prolong the prediction time. Furthermore, we leverage the autoregressive model to solve the scale insensitive problem of the neural network, making our model more robust. Specifically, we combine the OMNI data measured at Lagrangian Point 1 (L1) with the extreme ultraviolet images observed by the Solar Dynamics Observatory satellite to predict the solar wind speed at L1. Compared with the baseline models, GTA obtains significant performance improvements. Through visualization, we find GTA excavates the relationships between multiply variables without domain prior knowledge, which may help us find other unknown associations in heliophysics data sets. The data and code are available from https://github.com/syrGitHub/GTA.
Path following of autonomous surface vehicles with line-of-sight and nonlinear model predictive control

This paper proposes a novel quasi-infinite nonlinear model predictive control (NMPC) method for the path following of autonomous surface vehicles (ASVs). Firstly, the nonlinear ASV dynamics are converted into path following error dynamics characterizing the relationship between the ASV and the predefined reference path. In this way, the original tracking control problem is transformed into a stabilization problem and the problem size is reduced due to fewer variables. The proposed quasi-infinite NMPC is then applied to ensure that the error states converge to the origin with designed closed-loop system stability. Moreover, within the framework of Line-of-sight (LOS) guidance, the convergence of the error dynamics to the origin guarantees that the convergence of the ASV to the reference path. In addition, we improve the terminal constraints and terminal costs in the conventional quasi-infinite NMPC scheme so that a larger region of attraction is achieved. Simulation results demonstrate the effectiveness and certain degree of robustness of the proposed NMPC based ASV path following approach.
Nutritional Status and Related Factors in Patients with Gastric Cancer after Gastrectomy: A Cross-Sectional Study

Patients after gastrectomy for gastric cancer are at risk of malnutrition, and poor nutritional status negatively affects patients’ clinical outcomes. Knowledge of the factors influencing patients’ nutritional status can inform interventions for improving patients’ nutrition. A cross-sectional study was conducted to describe nutritional status and related factors in gastric cancer patients after gastrectomy. A convenience sample of gastric cancer patients with gastrectomy was recruited from general surgery or oncology clinics of a medical center in northern Taiwan. Data were collected with self-reported questionnaires, including the Functional Assessment Cancer Therapy—Gastric Module version 4, the Concerns in Meal Preparation scale, the Center for Epidemiologic Studies Depression Scale, and the Mini Nutrition Assessment. One hundred and one gastric cancer patients participated in the study. There were 81 cases of subtotal gastrectomy and 20 cases of total gastrectomy. Most patients (52.5%) were malnourished or at risk. Linear regression showed that symptom severity (β = −0.43), employment status (β = 0.19), and difficulty in diet preparation (β = −0.21) were significant predictors of nutritional status. Together, these three variables explained 35.8% of the variance in patient nutritional status (F = 20.3, p < 0.001). More than 50% of our participants were malnourished or at risk for malnutrition, indicating a need for continued monitoring and support after discharge from hospitals. Special attention should be given to patients with severe symptoms, unemployment, and difficulties in diet preparation.
Effects of Cell Phone Dependence on Mental Health Among College Students During the Pandemic of COVID-19: A Cross-Sectional Survey of a Medical University in Shanghai

Objective To investigate the effects of cell phone dependence (CPD) on mental health among undergraduates during the COVID-19 pandemic and further identify the determinants that may affect their mental health in China. Methods The data were collected from 602 students at a medical school in Shanghai via an online survey conducted from December 2021 to February 2022. The Mobile Phone Addiction Index (MPAI) and Depression Anxiety Stress Scale (DASS) were applied to evaluate CPD and mental health, respectively. Independent sample t-test and one-way analysis of variance (ANOVA) were employed to compare the means of continuous variables among categorical groups. Correlations between continuous variables were detected using Pearson's correlation analysis. Univariable and multivariable logistic regressions were employed to identify the determinants of mental health. Results Among the 402 eligible students, 73.88% were women with an average age of 20.19 ± 2.36 years. On average, the DASS score was 32.20 ± 11.07, the CPD score was 36.23 ± 11.89, and the cell phone use duration was 7.67 ± 3.61 h/day. CPD was found to have a negative effect on mental health among college students in Shanghai. Additionally, cell phone use duration, age, being senior students, faculty-student relationship, insomnia, tobacco use, obesity, and life satisfaction were clarified as contributing factors to mental health among college students. Conclusion High degree of CPD could have a negative effect on college students' mental health, which might lead to some psychological problems. Appropriate actions and effective interventions are highly needed to prevent severe psychological injuries among college students in China.
Influence Factors and Elimination on Iron Content Using ICP-AES Method in Oilfield Produced Water

ICP-AES method can be used to determine multiple metallic elements simultaneously, and has the advantages of high sensitivity, good repeatability and high accuracy. In the paper, the detection limit of iron content was determined by stepwise dilution method. The influence of the cationic concentration on the determination of iron element was studied, and the matrix matching method was proposed to eliminate the influence. The results show that, the determination limit of Iron element is 0.01 mg·L-1. Because the other cationic content is several times or even tens of times as much as iron ions, it has a great influence on the determination results of Iron element. The effects of cationic concentration can be effectively eliminated by establishing a standard curve using matrix matching. After digestion pretreatment on the oil and gas field produce water, The standard adding recovery rate was between 95% and 105%, and the RSD is less than 4%. Compare this method with o-phenanthroline spectrophotometry, its relative error is within 5%. Therefore, ICP-AES method can fully meet the requirements of determination of iron content in oil field produce water, and greatly improves the efficiency and accuracy of the laboratory analysis of oil and as field wastewater.