Miracle-dz/UniFAR-FTUs huggingface dataset:
Towards an understanding of the role of COPII subunits in vesicle coat assembly

In eukaryotic cells, proteins traversing the secretory pathway are transported from the endoplasmic reticulum (ER) to the Golgi apparatus by membrane-bounded vesicles formed by the recruitment and assembly of cytosolic coat components upon the ER membrane. Three cytosolic factors, collectively termed COPII, have been shown to be required for vesicle formation in the yeast S. cerevisiae: the Sec23p/Sec24p protein complex, the Secl3p/Sec31p protein complex, and the small GTP-binding protein Sarilp. Recent evidence suggests that the membrane-associated protein Secl 6p also participates in the formation of the vesicle coat, and may be considered an additional component of the COPII complex. To better understand the role of COPII subunits, we have adopted two different approaches: 1. Identification of yeast proteins that are associated with COPII subunits. We have found that Sec31p binds not only Secl3p, but also Secl6p, Sec23p, and Sec24p. A different region of Sec31 p appears to mediate each of these interactions. In addition, we have shown that the binding of Sec31 p to Secl 6p is necessary for ER to Golgi transport. We propose that Secl6p organizes the assembly of a coat which is stabilized both by the interaction of Sec3l p with Sec23p and Sec24p, as well as by the interaction of all three of these components with Secl6p. 2. Identification and characterization of COPII homologs in mammalian cells. We have shown that although the mammalian homolog of SEC13, Sec 13R, does not complement a secl3-1 mutant, chimeric constructs representing the N-terminal half of either Secl3p or Secl3Rp, and the Cterminal half of the other protein, are able to complement the sec13-1 secretion defect. We have also demonstrated that in mammalian cells, Sec13Rp is localized to the cisternae and vesicles in the region of the transitional ER. In addition, we have shown that yeast Secl3p and human Sec13Rp both interact with the same region of yeast Sec31 p. Collectively, these results suggest that the function of Secl3p -and of the COPII coat as a whole -has been evolutionarily conserved. Thesis Supervisor: Chris A. Kaiser Title: Associate Professor of Biology
Comparison of fibre optic sensors and digital image correlation for strain measurement in reinforced concrete beams

Currently, monitoring projects for civil structures rely heavily on conventional vibrating wire strain gauges, which while robust and accurate are also expensive and offer only discrete strain data points. As infrastructure around the world continues to deteriorate, engineers tasked with assessing these assets require more information about structural performance and data to validate the results of numerical assessments. Two technologies that offer tremendous potential in this regard are distributed fibre optic sensors (FOS) and digital image correlation (DIC). However, these systems require validation against conventional strain measurement techniques in order to ensure that they provide the required accuracy. The research presented compares measurements made with both FOS and DIC to results from conventional strain gauges on reinforced concrete beams during loading in the linear-elastic range. Two beams are tested in four point bending with all three sensor systems installed in the shear span where linear-elastic beam behaviour is expected. The strain results are presented for all three sensor systems. Good agreement between the FOS and strain gauges is observed. Out of plane movement is determined to be a major potential source of error for DIC measurements. Recommendations are made for procedures to achieve accurate measurements with FOS and DIC in field applications.
Exclusive Brand Outlet Expansion Framework for Lifestyle Brands in India (EBOE-LS)

Though EBOs’ (Exclusive Brand Outlet) risk-mitigation is a collective responsibility of lifestyle brand and the expansion partner (franchisee), a majority of lifestyle brands in India believe that the risk of capital investment/recurring expenses of EBOs and profit generated by EBOs has to be owned by the expansion partner. This belief and unbalanced business strategy of lifestyle brands though attract franchisees in the early stages of EBO expansion due to the brand’s reputation in the market or initial lucrative contract terms, it seriously fails to bring any long-term strategic and competitive advantages to the lifestyle brand as the drop-out rate of expansion partners increase significantly after one year of operation. This belief is also distracting lifestyle brands from understanding the long-term positive impact of EBO expansion frameworks that could balance the risk-mitigation and profits between the brand and the expansion partner. A single theory, model and framework of ‘Firm-Contracts’ and ‘Distribution Systems’ from the existing literature available across perspectives, paradigms, and areas of study (Economics, Business Law, Market Penetration, Business Strategy, Marketing and so on) is not entirely applicable that could be adopted to suit lifestyle brand’s EBO expansion plan in India and designing a framework without empirical pieces of evidence is also not appropriate. In this study, (i) we have studied existing theories, models and frameworks relevant to market penetration and expansion; (ii) analyzed 24 months’ of actual EBO data of a few select organized lifestyle brands in India across their existing expansion models; (iii) borrowed experimental findings and insights from previous studies relevant in this context, to identify key decision and investment-making areas that could result in a balanced business contract between a lifestyle brand and the expansion partner thereby designing an economical/effective framework that would be useful in deployment of appropriate tactics of deciding a right EBO type for every City Type and the Store Location by a lifestyle brand in India. The framework is named as EBOE-LS.
Pengaruh Ekstrak Daun Suren dan Daun Mahoni terhadap Mortalitas dan Aktivitas Makan Ulat Daun (Plutella xylostella) pada Tanaman Kubis

Plutella xylostella is one of pests which can cause damage of cabbage plants. One of the ways in controlling this pest is using biopesticides, i.e. mahogany and surian leaf extracts. This research aimed to identify the effect of extract leaves of suren, mahogany and suren+mahogany to mortality and eating activity of Plutella xylostella on cabbage plants. The research used two direction of ANAVA i.e. the type and extract concentration. The extracts used were from suren, mahogany and suren+mahogany leaves, with concentration 6% suren extract, 8% suren extract, 10% suren extract, 6% mahogany extract, 8% mahogany extract, 10% mahogany extract, 6% suren+mahagony extract, 8% suren+mahogany extract, 10% suren+mahogany extract. This research was conducted in 3 replications using 10 second instar larvae of Plutella xylostella for each treatment. Research parameters observed were mortality and eating activity of Plutella xylostella. Data are analyzed using Varians Analyze. The results of the research showed that the present of mahogany and suren leaf extracts influence the mortality and eating activity of Plutella xylostella. The treatment of 10% suren extract showed a higher influence than other treatments are cause mortality 85% and eating activity 57%.
SYNTHESIS OF AL5052-SIC-GRAPHITE METAL MATRIX COMPOSITE AND ASSESSMEMT OF ITS

The current work deals with the concoction associated tribological analyse of the Al5052-sic-graphite composite. The metal elite was Al5052 and sic-graphite contents in numerous percentages were strengthened in it to fabricate the specified metal matrix composite(MMC). Stir casting process was accustomed to fabricate the MMC with five-hitter of assault content and three of carbon content in Al5052. Tribological ananlysis of the composite fashioned between sleek —the graceful —the sleek surface of forged iron disc and smooth MMC pin has been thought-about and friction force and wear of the MMC were examine by mistreatment pin-on-disc setup. it absolutely was discovered that 1 International Journal of Pure and Applied Mathematics Volume 120 No. 6 2018, 1947-1965 ISSN: 1314-3395 (on-line version) url: http://www.acadpubl. eu/hub/ Special Issue http://www.acadpubl. eu/hub/
THREAT ANALYSIS OF STEGANOGRAPHIC AND COVERT COMMUNICATION IN NUCLEAR I&C SYSTEMS

Steganographic and covert communication is increasingly used for hiding attacks. Often information hiding is used by attackers in advanced persistent threats in order to operate without being noticed. Attackers might use it to hide data exfiltration or control channels for persistent malware. The paper analyzes potential threats to operational technology by investigating different communication protocols towards their suitability as cover channels. Using a generalized network architecture model and the communication flows of nuclear power plants, the attack potential using information hiding is exemplary assessed. An example for a supply chain attack for command injection is given on the foundation of the OPC UA protocol and an off-the-shelf programmable logic controller. Subsequently, recommendations for a strategic and operational preparation for operators towards the prevention and detection of information hiding attacks are derived.
Factors affecting the dividend policy of non-financial joint-stock companies in Ukraine

Dividend policy, as part of corporate governance, is largely dependent on the institutional environment in which companies operate. The study aims to determine factors affecting dividend policy in the conditions of the Ukrainian underdeveloped stock market, legal insecurity of minority shareholders, high cost and concentration of capital. For this purpose, hypotheses about the impact of a company’s financial state, size, business risk, and ownership structure on dividend payments were tested using a sample of 58 Ukrainian non-financial public joint-stock companies and applying Interactive tree classification techniques (C&amp;RT). The resulting classification model for predicting dividend decisions correctly classifies 92.86% of companies that paid dividends and 93.3% of companies that did not. The findings, based on the classification tree and importance scale, prove the hypothesis that companies in which individuals and institutional investors have a controlling interest are more likely to pay dividends than other non-state companies. The financial indicators accurately classify only those firms that do not pay dividends, and business risk does not affect classification accuracy at all. The paper substantiates the ways of using the study findings for economic regulation, protection of minority shareholders’ rights, and proliferation of modern corporate governance practices.
Abstract for Transgressing Food Workshop

This chapter explores the potential of multi-stakeholder standards initiatives (MSIs) to open up new spaces for engagement between the private sector, trade unions, NGOs and others for dialogue and action to promote labour rights. We focus primarily on an MSI in Kenya, HEBI. MSIs in agri-food chains represent a new form of ethical policy space, which are being created at multiple levels and locations, primarily because of processes at an international level. Through our analysis of the power dynamics in Kenyan cut flowers, we seek to build up an understanding of the politics of specific MSIs, and broader trajectories of transgression into corporate activity and vice versa. Despite momentum leading to increased participation in governance in public policy, the creation of ‘invited’ or ‘claimed spaces’ on their own cannot alter power or change the status quo; in the context of significant power imbalances the potential of MSIs to effect change is severely limited. This is because overarching power relations shape the space – sometimes leading to the sidelining of alternative voices. The private sector is not monolithic and there are divergences of approach, yet ethical sourcing and stakeholder engagement in these spaces is not yet, nor is it likely to lead to a transformation of worker rights. In a context of such significant power inequalities in value chains, more powerful actors tend to control social discourse and material resources, shaping the outcomes of new spaces in their own interests. This will continue to be the case whilst support is lacking for workers, smallholders and local communities to articulate their own narratives about ethics in
Human Activity Recognition using Convolutional 3D Network

: Activity Recognition (AR) also referred as Action Recognition, is an elementary problem in emerging field of Computer Vision (CV). Specifically, Human action Recognition (HAR) is a problem in CV, based on classification and it involves the process of identifying the human movements. Nowadays it is a growing area of research and has gained popularity because of its wide range of applications including robotics and video surveillance. With the blooming of science and technology, the scientific milestones in the field of HAR are been achieved more rapidly. Today, most of the recent successful studies in this area of HAR are focused on Deep Learning (DL). In the field of Image recognition, DL techniques have outperformed the other techniques. Thus, this work aims to develop a 3D CNN for the Human Activity Recognition from videos. The model extracts features from both the spatial and the temporal dimensions by performing 3D convolutions, thereby capturing the information encoded in multiple adjacent frames of the video. Namely three activities - Boxing, Hand waving and Running, from KTH Dataset is used for the purpose of HAR.
Information Technology Freshmen’ Attitudes towards English Language Learning with Blended Learning Course at FPT Polytechnic College

— Driven by evidence of its ad vantages over either online or classroom teaching alone, blended learning has increased rapidly in many educational contexts around the world, including Vietnam. With the holistic purpose of improving the language teaching and learning quality for polytechnic students, the paper focused on the students’ attitudes towards the current English blended learning course. The survey study was conducted at FPT Polytechnic College (Ho Chi Minh City, Vietnam) with the participation of 139 Information Technology freshmen. The data were garnered through the 45-item-questionnaire, and were statistically analyzed by SPSS version 20.0. The findings show that the majority of the students exhibited their much positive attitudes towards four aspects: the overall quality of this course, the quality of the instructors, the course content, and the supportive services. Yet, some students were dissatisfied with the other aspect–technology system– as they often faced technological problems during online learning outside the class.
A minimal-assumption-based agent-based simulation model of the emergence of technological innovation

Although agent-based simulation has been increasingly used to study technological innovations, so far most applications have focussed on the diffusion and adoption process of innovations. The emergence of technological innovations, namely how new technologies come into being, has been less studied. The emphasis on simulation models faces their own obstacles, since the simulation models tend to have so many parameters that they are difficult for practitioners to understand, and hard for researchers to calibrate and verify empirically. This chapter intends to combine research on simulation models with the emergence of technological innovations by investigating RQ4: Is it possible to simulate the emergent process of innovation so as to provide decision support for innovation managers and policy makers? By breaking down the innovation system into activities instead of structural elements, we provide an alternative, minimal-assumption-based simulation model of the emergence of technological innovations. The emergence of technological innovations is simulated as a collective order arising from action-reaction chains of heterogeneous activities. The simulation model is calibrated and verified using an empirical innovation case, namely the Nylon innovation. The results contribute to a thorough understanding of the mechanisms concerning the emergence of technological innovations. Moreover, they provide a theoretical model with minimal assumptions for the simulation of the emergence of technological innovations.
PROCUREMENT CONTRACT: EXPLORING THE PRINCIPLE AND ISSUE IN THE MALAYSIAN CONTRUCTION INDUSTRY

Procuring buildings is different from procuring goods. In procuring goods, a buyer can benefit from price competition even for inferior goods with questionable quality. The scenario is different in the construction industry. The term “procurement system” which is different from “procurement contract” has been closely associated with procuring materials or buildings. The use of different terminologies motivates this study to look closely at the definitions of these terms. The literature shows that the terms “procurement system” and “procurement contract” are used interchangeably especially in the Western countries, but the term “procurement system” is more widely used by industry players in Malaysia. Despite the various terms used for “procurement contract”, in most countries, “fixed price” (FP) procurement contract has been more extensively used in the construction industry compared to “cost reimbursement” (CR). Besides, the concept of procurement contract as FP and CR, mainly used by Western economists, is also explored.
Factors Influencing Adoption of Cryptocurrency-Based Transaction from an Islamic Perspective

-This paper presents a user study of “perception of the cryptocurrency-based transaction from the Islamic views”. The motivation lies with the fact that some users of cryptocurrency-based transaction raised concern on the nature of transactions with Bitcoin. Specifically, some argued that Bitcoin can be easily used for illegal purposes. Therefore, “Technological Acceptance Model” was adopted and quantitative research methodology was utilized, to formulate and test some hypothesis that will lead to an establishment of a model. Sample of 306 participants was used in the study. The result of the hypothesis testing indicates that “Behavioral Intention to Use Cryptocurrency from the Islamic perspective” is influenced directly by Shari’ah Compliance, Perceived Ease of Use, Emotionality, Perceived Usefulness, and Financial Concern. As evident from the analysis, Emotionality is influenced directly by Financial concern and Shari’ah Compliance. Whereas, Behavioral Intention is influenced indirectly by Financial Concern. The sample is general and does not specify a specific group of study. This study has contributed to understanding the Islamic issues behind the implementation of Cryptocurrency. This study adopted.
An Input Voltage Feed Forward based Two Switch Buck Boost DC-DC Converter

In recent years the use of buck-boost converters are more when compared to other type of converters. When compared with the basic converters like Cuk, zeta the two switch buck-boost converter (TSBB) presents less voltage losses on the switches. The two switch buck-boost converter requires fewer passive components can effectively reduce the conduction and switching losses, leading to high efficiency over a wide input voltage range. The TSBB converters has been extensively used in telecommunications, battery operated vehicles etc. with wide input voltage range. So it is thus important to improve the efficiency of TSBB converter over a high input voltage range. So in the telecommunications systems and fuel cells the TSBB converter input voltage fluctuates with output power, due to the input voltage response is not satisfactory. If the input transient voltage response is not satisfactory it creates problems on the output response of the system.so in addition to these TSBB converter we use input voltage feed forward method (IVFF) to improve the input transient response and reduces the effect of input voltage disturbances on the output of the system. These input voltage feed forward compensation is then proposed for two switch buck boost converter which realizes the automatic selections of operating modes and input voltage feed forward functions. The smooth switching between boost and buck modes is guaranteed with converter by representing its characteristics using Matlab/Simulink.
Predecessor Search

The predecessor problem is a key component of the fundamental sorting-and-searching core of algorithmic problems. While binary search is the optimal solution in the comparison model, more realistic machine models on integer sets open the door to a rich universe of data structures, algorithms, and lower bounds. In this article, we review the evolution of the solutions to the predecessor problem, focusing on the important algorithmic ideas, from the famous data structure of van Emde Boas to the optimal results of Patrascu and Thorup. We also consider lower bounds, variants, and special cases, as well as the remaining open questions.
Total Protein Concentrations in Brain Regions and Testicular/Tubal Fluids of Rabbits Fed Cassava Peel Meal as Replacement for Maize

Cheaper unconventional feed materials whose metabolizable energy is similar or closed to maize could be used in animal diets. This study investigated the effect of replacing maize with cassava peel meal (CPM) on the total protein concentrations in the brain regions and testicular/tubal fluids of rabbits. Sixty crossed bred weaned rabbits with an average initial bodyweight of 559.58 ± 0.42g/ rabbit were used. The animals were assigned to experimental diets using a completely randomised design. Five experimental diets were formulated with ratios of 100:0, 75:25, 50:50, 25:75 and 0:100 maize: sun dried CPM for T1, T2, T3, T4 and T5, respectively. At the end of the feeding trial, six rabbits per treatment were sacrificed by stunning and decapitation. The heads were severed and immediately dissected for brain harvest. The various brain regions were separately homogenized. The testes and epididymis of the bucks as well as segments of the female reproductive tract were also homogenised and total protein concentrations determined by the biuret method. Results showed that the total protein concentrations in all the brain regions were significantly (P < 0.05) affected by dietary treatments except the medulla oblongata. The protein concentration decreased as the level of CPM replacement increases with 100% level recording the least values. The protein concentration in the testicular/tubal fluids recorded a fluctuating trend that could not be ascribed to diets. The study concluded that cassava peel meal could serve as a better substitute for maize up to 75% without any serious adverse effects on the brain and reproductive organs of rabbits.