Miracle-dz/UniFAR-FTUs huggingface dataset:
Analysis of OFDMA receiver with carrier frequency offset and common carrier frequency offset (CCFO)

The technique of Orthogonal frequency multiplexing (OFDM) is used to mitigate the multipath effects and to achieve better data rate. When these systems are extended to enable multiple access wireless multimedia communications they are more beneficial. The performance of the OFDM systems degrades with frequency offset and phase offset. The OFDM multiple access (OFDMA) technology allots groups of the OFDM subcarriers allocated to different users for transmission. In this paper we study the interference effects of the individual subcarriers with the neighbouring subcarriers which also plays a role in the system degradation is termed as Multiuser Interference (MUI). The effect of Carrier frequency offset (CFO) on these systems is also taken in account. There are conventional CFO compensation methods for OFDMA systems the CFOs are usually compensated by directly eliminating the intercarrier interference (ICI) caused by the residual CFOs for individual users.
Spatial interference scale as a determinant of microbial range expansion

This study establishes the spatial scale of cellular interaction as a key determinant of microbial range expansion. In microbial communities, social interactions such as competition occur ubiquitously across multiple spatial scales from local proximity to remote distance. However, it remains unclear how such a spatial variation of interaction contributes to the structural development of microbial populations. Here, we developed synthetic consortia, biophysical theory, and simulations to elucidate the role of spatial interference scale in governing ecosystem organization during range expansion. For consortia with unidirectional interference, we discovered that, at growing fronts, the extinction time of toxin-sensitive species is reciprocal to the spatial interference scale. In contrast, for communities with bidirectional interference, their structures diverge into distinct monoculture colonies under different initial conditions, with the corresponding separatrix set by the spatial scale of interference. Near the separatrix, ecosystem development becomes noise-driven and yields opposite structures. Our results establish spatial interaction scale as a key determinant for microbial range expansion, providing insights into microbial spatial organization and synthetic ecosystem engineering.
Comparative Assessment of Scoring Functions: The CASF-2016 Update

In structure-based drug design, scoring functions are often employed to evaluate protein-ligand interactions. A variety of scoring functions have been developed so far, and thus, some objective benchmarks are desired for assessing their strength and weakness. The comparative assessment of scoring functions (CASF) benchmark developed by us provides an answer to this demand. CASF is designed as a "scoring benchmark", where the scoring process is decoupled from the docking process to depict the performance of scoring function more precisely. Here, we describe the latest update of this benchmark, i.e., CASF-2016. Each scoring function is still evaluated by four metrics, including "scoring power", "ranking power", "docking power", and "screening power". Nevertheless, the evaluation methods have been improved considerably in several aspects. A new test set is compiled, which consists of 285 protein-ligand complexes with high-quality crystal structures and reliable binding constants. A panel of 25 scoring functions are tested on CASF-2016 as a demonstration. Our results reveal that the performance of current scoring functions is more promising in terms of docking power than scoring, ranking, and screening power. Scoring power is somewhat correlated with ranking power, so are docking power and screening power. The results obtained on CASF-2016 may provide valuable guidance for the end users to make smart choices among available scoring functions. Moreover, CASF is created as an open-access benchmark so that other researchers can utilize it to test a wider range of scoring functions. The complete CASF-2016 benchmark will be released on the PDBbind-CN web server ( http://www.pdbbind-cn.org/casf.asp/ ) once this article is published.
The interpretation of partial Patterson functions and its application to structure analyses of serandite Mn2NaHSi3O9 and banalsite BaNa2Al4Si4O16

Auszug Ein allgemeines Verfahren zur Zerlegung der Vektorsätze aus zentrosymmetrischen Sätzen von positiven und negativen Punkten wird beschrieben. Die für einen Vektorsatz charakteristischen negativen Bilder können mit Erfolg zur Lokalisierung von Inversionsbildern benutzt werden. Mehrfache Lösungen von Vektorsätzen, die möglichen Typen multipler Bilder entsprechen, werden diskutiert. Das Verfahren kann im allgemeinen zur Deutung partieller PattersonFunktionen von Überstrukturen angewandt werden, wenn sie aus den Überstruktur-Interferenzen allein berechnet sind. Als Beispiel für die Anwendung wird die Analyse der Strukturen von Serandit und Banalsit, die beide QuaeiPerioden aufweisen, behandelt. Abstract A general procedure has been described of decomposing vector sets of centrosymmetrical sets of positive and negative unit points. The negative images which are characteristic of the vector sets can effectively be utilized to locate inversion images. Multiple solutions of the vector sets due to possible types of multiple images are discussed. The procedure can readily be exploited, in general, for the straightforward interpretation of partial Patterson functions of superstructures calculated from superstructure reflections alone. Examples of applying this procedure have been shown to the structure determinations of serandite and banalsite, both having strong quasi-periodicities.
PCR for Diagnosing Helicobacter pylori Infection in Moroccan Patients: Comparison with ELISA and Histopathological Tests

Helicobacter pylori (H. pylori) infection is a real public health problem. In Morocco, 70% of the populations are infected by this pathogen. Several techniques are used for the detection of H. pylori infection. In Morocco, histopathological examination and enzyme-linked immunosorbent assay (ELISA) are the most commonly used tests. Our aim is to compare the sensitivity and the specificity of these two techniques with the polymerase chain reaction (PCR) which is not used currently in Morocco. In this study, biopsies of 60 chronic gastritis patients were used for histopathological examination and for the detection of ureA gene by Nested-PCR. Blood samples were used for ELISA.H. pylori was detected in 57 (95%) patients by histopathological examination, 60 (100%) by PCR and 46 (77%) by ELISA. Sensitivity and specificity are calculated using Histopathological examination and PCR findings as gold standard. ELISA test had the lowest specificity (79%), followed by histopathological examination (95%), whereas PCR had the highest specificity (100%). The use of PCR test showed a good result in term of sensitivity and detection. Then, it should be recommended to use PCR for routine diagnosis of H. pylori infection.
Athens Institute for Education and Research ATINER ATINER ' s Conference Paper Series WAT 2015-1693

The presence of regulated quantities of residual disinfectant is a usual feature in water supply systems (WSSs); nevertheless, biofilm formation persists in all of them, representing a paradigm in WSSs management due to the numerous undesirable problems associated. This study attempts to create a biofilm model based on a limited number of basic interactions between bacteria and the hydraulic and physical characteristics of the pipes by the step-wise evolution of biofilm over time. Multi-Agent Systems (MASs) are used as a modelling tool to achieve this purpose, arising as an excellent starting point for further researches. A MAS consists of a population of autonomous entities (agents, biofilm bacteria in this case) situated in a shared structured framework (environment, pipes in this case). These agents operate independently but also are able to interact with their environment, coordinating themselves with other agents. By obtaining a MAS based biofilm model, it will be possible to achieve a better understanding on any situation of interest because different research scenarios could be simulated allowing to check the hypotheses on their mechanisms and to predict how biofilm evolves in WSSs.
Chapter 2 Exposure Measurement and Prevalence 2 . 1

This chapter provides background information on the prevalence and measurement of exposure to ETS, and emphasizes investigation and monitoring methods used in epidemiological evaluations of health effects. Section 2.2 briefly reviews the physical and chemical properties of ETS, and identifies some of the important biologically active constituents present in ETS. Section 2.3 discusses various techniques that have been used to measure ETS concentrations in indoor environments. Determination of ETS contamination is a challenge as ETS is a complex mixture of over 4,000 compounds and it is neither feasible nor practical to characterize every individual constituent of ETS. Given the complex nature of ETS, markers and tracers of ETS are measured to assess ETS exposures. The role and limitations of some ETS markers, such as nicotine, particulate matter in air, and polycyclic aromatic hydrocarbons, are discussed in this section. Section 2.4 addresses the use of biomarkers to measure ETS exposure. In addition to ETS concentration in air, the level of biomarker measured is also dependent on an individual’s uptake, distribution, metabolism, and excretion of the chemical of interest. This section describes the use and limitations of some of the biomarkers, such as nicotine and cotinine in physiological fluids, in determining ETS exposure.
Solving Facility Location Problem on Cluster Computing

— Computation of facility location problem for every location in the country is not easy simultaneously. Solving the problem is described by using cluster computing. A technique is to design parallel algorithm by using local search with single swap method in order to solve that problem on clusters. Parallel implementation is done by the use of portable parallel programming, Message Passing Interface (MPI), on Microsoft Windows Compute Cluster. In this paper, it presents the algorithm that used local search with single swap method and implementation of the system of a facility to be opened by using MPI on cluster. If large datasets are considered, the process of calculating a reasonable cost for a facility becomes time consuming. The result shows parallel computation of facility location problem on cluster speedups and scales well as problem size increases.
Award Number: W81XWH-10-1-0244 TITLE: Loss of PTEN as a Predictive Biomarker of Response to Lithium Chloride, A Potential Targeted Treatment for Breast Cancer

Purpose:We sought to evaluate the feasibility of detecting PIK3CAmutations in circulating tumor DNA (ctDNA) from plasma of patients with metastatic breast cancer using a novel technique called BEAMing. Experimental Design: In a retrospective analysis, 49 tumor and temporally matched plasma samples from patients with breast cancer were screened for PIK3CAmutations by BEAMing. We then prospectively screened the ctDNA of 60 patients with metastatic breast cancer for PIK3CA mutations by BEAMing and compared the findings with results obtained by screening corresponding archival tumor tissue DNA using both sequencing and BEAMing. Results: The overall frequency of PIK3CA mutations by BEAMing was similar in both patient cohorts (29% and 28.3%, respectively). In the retrospective cohort, the concordance of PIK3CAmutation status by BEAMing between formalin-fixed, paraffin-embedded (FFPE) samples and ctDNA from temporally matched plasma was 100% (34 of 34). In the prospective cohort, the concordance rate among 51 evaluable cases was 72.5%between BEAMing of ctDNA and sequencing of archival tumor tissueDNA.When the same archival tissue DNA was screened by both sequencing and BEAMing for PIK3CA mutations (n 1⁄4 41 tissue samples), there was 100% concordance in the obtained results. Conclusions: Analysis of plasma-derived ctDNA for the detection of PIK3CAmutations in patients with metastatic breast cancer is feasible. Our results suggest that PIK3CA mutational status can change upon disease recurrence, emphasizing the importance of reassessing PIK3CA status on contemporary (not archival) biospecimens. These results have implications for the development of predictive biomarkers of response to targeted therapies. Clin Cancer Res; 18(12); 1–8. 2012 AACR.
Multirobot Cooperative Model Applied to Coverage of Unknown Regions

This chapter describes the problems of robotic exploration and coverage, and also presents the main characteristics that must include a multirobot platform in order fulfill such task in terms of general architecture, goals and cooperativeness. It is described a validated model for multirobot exploration called Backtracking Spiral Algorithm – Cooperative Multirobot, BSA-CM. Exploration and coverage of unknown regions are tasks that have been developed by human beings throughout history. Nevertheless, tasks that imply lands under hazardous or hostile circumstances such as planetary exploration (Menzel, 2000), humanitarian demining (Freese et al., 2007), environmental cleaning (Tilden, 1996) of dangerous materials as radioactive or military remainders leads to delegating such exercise to robots. The main issue is to protect human life at all cost. In this particular case, by unloading the people of tasks in daily routine that implies covering of regions. Exploration of unknown areas and lands, and also execution of complex tasks in unknown or partially structured regions, is an extremely complex job for an independent robot, given the nature of the algorithms and intelligence and reasoning levels whereupon are equipped the robots (Murphy, 2000). Nevertheless, the possibility of having robotic platforms able to explore these spaces is becoming more and more a fundamental necessity in the development of autonomous mobile robots. The subject of covering and exploration with robotic entities has been boarded from different optical but in case of multi-robot systems, the challenge just begins. Systems that involve several robots can present advantages over those that include a single robot of great power, processing capacity and cost. First of all, a robot team can cover an area more quickly than a single robot. On the other hand, the exploration performed by a set of robots is robust due to the added redundancies and allows to have a notion of the best next point of view to gain information of the area where a single system would fail (Balch & Parker, 2002). After a review of different approaches to the coverage problem with robots, it is possible to conclude that such solutions are subscribed in one of two main groups depending on the movement strategy chosen to solve the problem of coverage: those that use Non-Structured trajectories, where the navigation of the robots depends on the search of the best next point of view that derives in the elimination of borders of the unknown world, or, by means of
Zoning, Transferable Development Rights, and the Density of Development

In this paper, we explore the effect of low-density zoning regulations and other factors on subdivision density. Using a unique dataset of new subdivisions built over a 34-year period in Calvert County, Maryland, we econometrically estimate a density function using both ordinary-least-squares (OLS) and censored regression. The variability in density permitted by the county’s zoning and transferable development right (TDR) rules over the sample period allows us to assess the relative importance of market factors and regulatory constraints on density. We use the censored model to predict what density patterns would have been without zoning.
Open Access book publisher

This book describes some devices that are commonly identified as tactile or force sensors. This is achieved with different degrees of detail, in a unique and actual resource, through the description of different approaches to this type of sensors. Understanding the design and the working principles of the sensors described here requires a multidisciplinary background of electrical engineering, mechanical engineering, physics, biology, etc. An attempt has been made to place side by side the most pertinent information in order to reach a more productive reading not only for professionals dedicated to the design of tactile sensors, but also for all other sensor users, as for example, in the field of robotics. The latest technologies presented in this book are more focused on information readout and processing: as new materials, micro and sub-micro sensors are available, wireless transmission and processing of the sensorial information, as well as some innovative methodologies for obtaining and interpreting tactile information are also strongly evolving.
Role of High Dose Imatinib in BCR/ABL/Ph CML

s), Abstr. 2271. Rea, D. ; Etienne, G. ; Corm, S. ; Cony-Makhoul, P.; Gardembas, M. ; Legros, L. ; Dubruille, V. ; Hayette, S. ; Mahon, F.X. ; Cayuela, J.M. & Nicolini, F.E. (2009). Imatinib dose escalation for chronic phase-chronic myelogenous leukaemia patients in primary suboptimal response to imatinib 400 mg daily standard therapy. Leukemia, Vol. 23 (6), pp. 1193-1196. Rudzki, J. & Wolf, D. (2011). Dose escalation of imatinib in chronic-phase chronic myeloid leukemia patients: is it still reasonable? Expert Rev Hematol, Vol. 4 (2), pp. 153-159. Sawyers, C.L. ; Hochhaus, A. ; Feldman, E. ; Goldman, J.M. ; Miller, C.B. ; Ottmann, O.G. ; Schiffer, C.A. ; Talpaz, M. ; Guilhot, F. ; Deininger, M.W. ; Fischer, T. ; O'Brien, S.G. ; Stone, R.M. ; Gambacorti-Passerini, C.B. ; Russell, N.H. ; Reiffers, J.J.; Shea, T.C. ; Chapuis, B. ; Coutre, S. ; Tura, S. ; Morra, E. ; Larson, R.A. ; Saven, A. ; Peschel, C. ; Gratwohl, A. ; Mandelli, F. ; Ben-Am, M. ; Gathmann, I. ; Capdeville, R. ; Paquette, R.L. & Druker, B.J. (2002). Imatinib induces hematologic and cytogenetic responses in patients with chronic myelogenous leukemia in myeloid blast crisis: results of a phase II study. Blood, Vol. 99 (10), pp. 3530-3539. Silver, R.T. ; Cortes, J.; Waltzman, R. ; Mone, M. & Kantarjian H. (2009). Sustained durability of responses and improved progression-free and overall survival with imatinib treatment for accelerated phase and blast crisis chronic myeloid leukemia: longterm follow-up of the STI571 0102 and 0109 trials. Haematologica, Vol. 94 (5), pp. 743-744. Sokal, J.E. ; Cox, E.B. ; Baccarani, M. ; Tura, S. ; Gomez, G.A. ; Robertson, J.E. ; Tso, C.Y. ; Braun, T.J.; Clarkson, B.D. & Cervantes, F. (1984). Prognostic discrimination in "good-risk" chronic granulocytic leukemia. Blood, Vol. 63, pp. 789-799. Talpaz, M. ; Silver, R.T. ; Druker, B.J.; Goldman, J.M. ; Gambacorti-Passerini, C. ; Guilhot, F. ; Schiffer, C.A. ; Fischer, T. ; Deininger, M.W. ; Lennard, A.L. ; Hochhaus, A. ; Ottmann, O.G. ; Gratwohl, A. ; Baccarani, M. ; Stone, R. ; Tura, S. ; Mahon, F.X. ; FernandesReese, S. ; Gathmann, I. ; Capdeville, R. ; Kantarjian, H.M. & Sawyers, C.L. (2002). Imatinib induces durable hematologic and cytogenetic responses in patients with accelerated phase chronic myeloid leukemia: results of a phase 2 study. Blood, Vol. 99 (6), pp. 1928-1937. Yeung, D.T. ; Osborn, M. ; White, D.L. ; Branford, S. ; Haswell, L. ; Slader, C. ; Issa, S. ; Hiwas, D.K. ; Hertzberg, M.S.; Schwarer, A.P.; Filshie, R. ; Arthur, C.K. ; Kwan, Y.L. ; Forsyth, C.J.; Ross, D.M. ; Mills, A.K. ; Grigg, A. & Hughes T. (2010). Selective escalation of imatinib therapy and early switching to nilotinib in de novo chronic phae CML patients: interim results from the TIDEL-II Trial. Blood (ASH Annual Meeting Abstracts), Abstr. 209s), Abstr. 209
2.13 Diffusion Models of Memory and Decision Making

This article was originally published in Learning and Memory: A Comprehensive Reference, 2nd edition, published by Elsevier, and the attached copy is provided by Elsevier for the author's benefit and for the benefit of the author's institution, for non-commercial research and educational use including without limitation use in instruction at your institution, sending it to specific colleagues who you know, and providing a copy to your institution's administrator.
Analyzing Analyst Research: A Review of Past Coverage and Recommendations for Future Research

As visible and knowledgeable experts who constantly collect, analyze, and disseminate information about the future prospects of publicly listed firms, financial analysts fulfill an important information brokerage and monitoring function for investors. By providing investment advice, financial analysts also influence the demand for a firm’s stock and thus its price. Executives pay close attention to financial analysts’ earnings forecasts and recommendations, so much so that they are frequently criticized for excessive focus on their forecasts at the expense of the long-term interests of the firm. But while research on analysts in strategic management is steadily growing, we lack a coherent understanding of the extent and nature of analysts’ diverse influences on executives’ and investors’ decision making and the context in which analysts operate. This is largely due to the fragmentation of the literature and the absence of prior reviews or meta-analyses of the topic. By organizing, synthesizing, and analyzing extant research efforts on analysts in the various domains of strategic management research, we aim to advance our knowledge on the influence of analysts on firms and investors. Further, we hope that our analyses and recommendations help further increase research coverage on this important organizational stakeholder.
Proton Testing of SEU Mitigation Methods for the Virtex FPGA

Total ionizing dose (TID), heavy ion and proton characterization have previously been performed on Virtex FPGAs, fabricated on epitaxial silicon, to evaluate the onorbit radiation performance expected for this technology. The dominant risk is Single Event Upset (SEU), so upset detection and mitigation schemes were developed and tested to demonstrate the improvement in the programmed functional upset sensitivity and the system consequence of upsets. The Xilinx prescribed SEU mitigation schemes were tested for a generic functional usage at the proton facility in UC Davis.
Using visualizations to teach problem-solving skills in mathematics: Which kind of visualization works?

In the experiment described in this paper we investigated the effects of different kinds of computer-based visualizations on the acquisition of problem-solving skills in the domain of probability theory. Learners received either purely text-based worked examples, text plus an instruction to mentally imagine the examples' contents, or they could retrieve either static pictures or concrete animations that depicted the problem statement and the problem states achieved by applying a specific solution step. It could be shown that frequently using static pictures or imagining the examples' contents both improved problem-solving performance on isomorphic problems. However, there were no positive effects of using animations. Rather, the frequent use of animations led to substantial increases in learning time, while it slightly decreased performance at the same time. Thus, the use of concrete animations to visualize solution procedures was more harming than helpful for conveying problem-solving skills.