Miracle-dz/UniFAR-FTUs huggingface dataset:
The EMBL data library

The EMBL Data Library was the first internationally supported central resource for nucleic acid sequence data. Working in close collaboration with its American counterpart, GenBank (1), the library prepares and makes available to the scientific community a comprehensive collection of the published nucleic acid sequences. This paper describes briefly the contents of the database, how it is available, and possible future enhancements of Data Library services.
Effect of nitrogen fertilization and Bradyrhizobium inoculation on the growth, symbiotic properties and yield of pigeon pea (Cajanus cajan)

A Pot and two field experiments were conducted to investigate the effect of rhizobium inoculation and nitrogen fertilizer on the growth, symbiotic properties and yield of pigeon pea. The first field experiment was conducted in season 2003 to test the need of pigeon pea for inoculation. The results showed that pigeon pea needs inoculation by active and effective strains. A pot experiment was conducted in season 2004 to select the most effective nitrogen fixing strains from three Bradyrhizobium strains and their combinations. A composite of USDA + CP strains proved to be the most effective of all strains tested because they increased the number of nodules and nodule dry weight by 93% and 80% respectively over the control. The third experiment was conducted for two seasons, (2005 and 2006) at Gezira Research Station farm to study the effect of fertilization with N starter dose and inoculation with the effective strains selected from the previous experiment on growth and yield of pigeon pea. The inoculation of pigeon pea with selected strains and fertilization with starter N dose gave, in both seasons, significantly higher seed and straw yields. Based on plant performance in both seasons the inoculation coupled with N fertilizer significantly increased all the parameters measured.
Selectivity and reusability study of functionalized ALD TiO2 evanescent wave sensors

The monitoring of bacteria concentration in drain fluid is the most common way to estimate the success of a colon surgery. The lack of efficient method to follow the development of E. coli in drain fluid after surgery is often fatal to the patient. Together with the first clinical symptoms, bacteria are an early and reliable indicator of anastomotic leakage one to three days after surgery. The proposed device helps to significantly reduce the diagnostic time to a few minutes, while providing a low cost solution. It uses an ALD TiO2 evanescent sensor properly functionalised. The selectivity of the sensor to Bacillus Subtillus is demonstrated and a minimum detection of 103 CFU/ml is measured. The sensors can be properly cleaned and reused up to 10 times without major deterioration of their performance.
Draft Genome Sequence of a Mexican Community-Associated Methicillin-Resistant Staphylococcus epidermidis Strain

ABSTRACT We report here the first draft genome sequence of a Mexican communitarian methicillin-resistant Staphylococcus epidermidis (MRSE) strain whose genome harbors a wide variety of resistance determinants. The availability of this genome will allow the study of antibiotic resistance in Mexican staphylococci from a genomic perspective.
Hydrothermal growth of ZnO nanowires on paper for flexible electronics

Seamless integration of functional nanomaterials on paper can boost the functionality of paper-based flexible electronics. In this article, we report the successful growth of zinc oxide nanowires (ZnO NWs) on paper substrate through a low-cost hydrothermal process. We experimentally confirm the necessity of ammonium hydroxide as assistant chemical in the growth solution. We quantify the growth rate of ZnO NWs over growth time, and characterize the electrical property of the ZnO-NW paper. To highlight potential applications of the ZnO-NW paper, we demonstrate the use of ZnO-NW paper for ultra-violet light and touch sensing. The presented work provides technical insight for successful hydrothermal growth of ZnO NWs on paper, and could further inspire novel utilization of ZnO-NW paper for flexible electronics.
Ultra-Precise Hybrid Lens Distortion Correction

A new hybrid method to realise high-precision distortion determination for optical ultra-precision 3D measurement systems based on stereo cameras using active light projection is introduced. It consists of two phases: the basic distortion determination and the refinement. The refinement phase of the procedure uses a plane surface and projected fringe patterns as calibration tools to determine simultaneously the distortion of both cameras within an iterative procedure. The new technique may be performed in the state of the device “ready for measurement” which avoids errors by a later adjustment. A considerable reduction of distortion errors is achieved and leads to considerable improvements of the accuracy of 3D measurements, especially in the precise measurement of smooth surfaces. Keywords—3D Surface Measurement, Fringe Projection, Lens Distortion, Stereo.
MINPL Optimization Of Timber TrussesConsidering Joint Flexibility

The paper presents the shape and discrete sizing optimization of timber trusses with the consideration of joint flexibility. The optimization was performed by the Mixed-Integer Nonlinear Programming (MINLP) approach. In the optimization model an economic objective function for minimizing the structure's selfmanufacturing costs was defined. The design conditions in accordance with Eurocode 5 were considered as optimization constraints. The internal forces and deflections were calculated by finite element equations. The structural stifness matrix was composed by considering fictiously decreased cross-sectional areas of all the flexibly connected elements. The cross-section dimensions and the number of fasteners were defined as discrete sizing variables, while the joint coordinates were considered as shape variables. The applicability of the proposed approach is demonstrated through a numerical example, presented at the end of the paper.
Dynamic Time Quantum based Round Robin CPU Scheduling Algorithm

In multiprogramming environment, CPU scheduling is the process to determine the most efficient way to service the requests of the processes waiting in the ready queue to be executed. The CPU scheduling algorithms focus on maximizing CPU utilization by minimizing waiting time, turnaround time and number of context switches for a set of processes. In time shared systems the preferred choice is Round Robin (RR) CPU scheduling in which performance of the system depends on the choice of the time quantum. This paper presents a dynamic time quantum based Round Robin CPU scheduling algorithm to enhance the CPU performance using the features of an Improved Round Robin (IRR) and an improved Round Robin CPU scheduling algorithm with varying time quantum (IRRVQ). The experimental and simulation results show that the proposed algorithm is proven better than the RR, IRR and IRRVQ in terms of decreasing the average waiting time, average turnaround time and number of context switches.
AMID, an Apoptosis-inducing Factor-homologous Mitochondrion-associated Protein, Induces Caspase-independent Apoptosis*

Apoptosis-inducing factor (AIF) is a mitochondrial flavoprotein that triggers caspase-independent apoptosis. We describe here the cloning and characterization of a novel AIF-homologous molecule designated AMID (AIF-homologous mitochondrion-associatedinducer of death). AMID lacks a mitochondrial localization sequence but shares significant homology with AIF and NADH oxidoreductases from bacteria to mammalian species. Immunofluorescent staining and biochemical experiments indicated that AMID was co-localized with mitochondria. Overexpression of AMID induced cell death with characteristic apoptotic morphology. Furthermore, AMID-induced apoptosis was independent of caspase activation and p53 and was not inhibited by Bcl-2. These findings suggest that AMID induces a novel caspase-independent apoptotic pathway.
Bulk Comptonization of the Cosmic Microwave Background by Extragalactic Jets as a Probe of Their Matter Content

We propose a method for estimating the composition, i.e., the relative amounts of leptons and protons, of extragalactic jets that exhibit X-ray-bright knots in their kiloparsec-scale jets. The method relies on measuring, or setting upper limits on, the component of the cosmic microwave background (CMB) radiation that is bulk Comptonized (BC) by cold electrons in the relativistically flowing jet. These measurements, along with modeling of the broadband knot emission that constrains the bulk Lorentz factor Γ of the jets, can yield estimates of the jet power carried by protons and leptons. We provide an explicit calculation of the spectrum of the BC CMB component and apply these results to PKS 0637-752 and 3C 273, two superluminal quasars with Chandra-detected large-scale jets. What makes these sources particularly suited for such a procedure is the absence of significant nonthermal jet emission in the "bridge," the region between the core and the first bright jet knot, which guarantees that most of the electrons there are cold, leaving the BC-scattered CMB radiation as the only significant source of photons in this region. At λ = 3.6-8.0 μm, the most likely band to observe the BC-scattered CMB emission, the Spitzer angular resolution (~1''-3'') is considerably smaller than the bridges of these jets (~10''), making it possible to both measure and resolve this emission.
Achievement of organisational goals and motivation of middle level managers within the context of the two-factor theory

The ever dynamic nature of the world of work requires that organisations constantly review factors that energise managers (particularly middle level managers) towards achievement of set goals. This category of employees translates strategic decisions by top management into action through the operational employees. They (middle level managers) therefore serve as a link between top management and the lower level employees thus making their role to be of outmost importance to the survival and competitiveness of any organisation thus necessitating the need of our present study. The study adopted a survey research method using quantitative research design. A measuring instrument with a Cronbach alpha coefficient of above 0.70 was developed and used to collect primary data. Non-random sampling technique using purposive/convenience sampling procedure was employed in deriving a sample size of 250 middle-level managers who participated in the survey. Main hypotheses were formulated and tested using the Chi-Square test to determine the level of association between intrinsic and extrinsic motivational variables and achievement of organisational goals by middle level managers. Results show that both intrinsic and extrinsic motivational variables impacted significantly on achievement of organisational goals by this category of managers. Based on this finding, we therefore recommend that organisations should combine both intrinsic and extrinsic motivational variables in the design of goal achievement strategy for middle level managers. DOI: 10.5901/mjss.2014. v5n16p53
Shape Similarity Index for Time Series based on Features of Euclidean Distances Histograms

Shape similarity between time series is quantified based on descriptive statistical features from histograms of Euclidean distances. The histogram shows the statistical distribution of point to point differences between two time series, using this representation of the compared time series, a shape similarity index was designed. The index quantifies the differences between histograms with respect to an ideal similarity histogram that corresponds to a reference time series, this index allows the ordering of a set of time series based on their similarity with respect to this time series. A benchmark set of time series with known similarities and dissimilarities was used in order to evaluate the performance of the proposed index. The experimental results show that this index is able to order and differentiate with good resolution the time series, by their similarity with respect to the reference time series
Managing physical and mental health conditions: Consumer perspectives on integrated care

ABSTRACT Despite the growing trend of integrating primary care and mental health services, little research has documented how consumers with severe mental illnesses (SMI) manage comorbid conditions or view integrated services. We sought to better understand how consumers perceive and manage both mental and physical health conditions and their views of integrated services. We conducted semi-structured interviews with consumers receiving primary care services integrated in a community mental health setting. Consumers described a range of strategies to deal with physical health conditions and generally viewed mental and physical health conditions as impacting one another. Consumers viewed integration of primary care and mental health services favorably, specifically its convenience, friendliness, and knowledge of providers, and collaboration between providers. Although integration was viewed positively, consumers with SMI may need a myriad of strategies and supports to both initiate and sustain lifestyle changes that address common physical health problems.
Stress, distress and mucosal immunity in carers of a partner with fronto-temporal dementia

Objectives: This study investigates the psychological and physiological impact of caring for a partner with fronto-temporal dementia (FTD). Carers were expected to exhibit greater stress and poorer psychological well-being in comparison with non-carers, and suppressed mucosal immunity. Method: Twenty-five carers and 36 non-carers completed standardised psychological assessments of perceived stress, psychological well-being, coping and social support. Levels of mucosal immunity were assessed in saliva samples collected over the 3 days of the study, alongside daily assessments of stress, arousal and mood. Results: Informal carers as a group reported greater stress and poorer psychological well-being, but there was considerable variation, with some carers reporting better psychological functioning than non-carers. Immune levels were not suppressed in carers compared with non-carers; counter to hypothesis, there was a positive correlation between immunity and poorer psychological well-being. Conclusions: This research suggests that caring for a partner with FTD increases distress and carers might benefit from psychological intervention. However, the variation in psychological well-being requires explanation. Furthermore, this first examination of mucosal immunity employing participants experiencing enduring stress suggests that, in contrast to previous research, enduring stress does not lead to suppression of mucosal immunity and may actually enhance it.
A power system simulation tool based on Simulink

This paper describes the Power System Blockset (PSB) from The MathWorks, Natick, MA, which is a new software package for the simulation of electric circuits, power systems, power electronic devices, and electric drives. The PSB is developed in the graphical Simulink environment of the general-purpose Matlab software. This blockset inherits a number of advantages from its development environment, namely, an open architecture, a powerful graphical user interface, and versatile analysis and graphics tools. The user can integrate control systems implemented with Simulink blocks directly into a diagram built with the PSB. Solution of differential equations is accomplished using the state-space approach with variable-step variable-order integration algorithms. A simulation example is presented, and the results are compared with those obtained with PSPICE.
A tm Plug-In for Distributed Text Mining in R

R has gained explicit text mining support with the tm package enabling statisticians to answer many interesting research questions via statistical analysis or modeling of (text) corpora. However, we typically face two challenges when analyzing large corpora: (1) the amount of data to be processed in a single machine is usually limited by the available main memory (i.e., RAM), and (2) the more data to be analyzed the higher the need for efficient procedures for calculating valuable results. Fortunately, adequate programming models like MapReduce facilitate parallelization of text mining tasks and allow for processing data sets beyond what would fit into memory by using a distributed file system possibly spanning over several machines, e.g., in a cluster of workstations. In this paper we present a plug-in package to tm called tm.plugin. dc implementing a distributed corpus class which can take advantage of the Hadoop MapReduce library for large scale text mining tasks. We show on the basis of an application in culturomics that we can efficiently handle data sets of significant size.
PET/MRI: Where might it replace PET/CT?

Simultaneous positron emission tomography and MRI (PET/MRI) is a technology that combines the anatomic and quantitative strengths of MR imaging with physiologic information obtained from PET. PET and computed tomography (PET/CT) performed in a single scanning session is an established technology already in widespread and accepted use worldwide. Given the higher cost and complexity of operating and interpreting the studies obtained on a PET/MRI system, there has been question as to which patients would benefit most from imaging with PET/MRI versus PET/CT. In this article, we compare PET/MRI with PET/CT, detail the applications for which PET/MRI has shown promise and discuss impediments to future adoption. It is our hope that future work will prove the benefit of PET/MRI to specific groups of patients, initially those in which PET/CT and MRI are already performed, leveraging simultaneity and allowing for greater degrees of multiparametric evaluation.
Negative differential resistance of AlGaAs/GaAs heterojunction bipolar transistors: influence of emitter edge current

We report an electrical characterisation of AlGaAs/GaAs heterojunction bipolar transistors over a temperature range of 250 to 400 K in which the emitter edge current contribution to the negative differential output resistance (NDR) effect is determined. A quantitative analysis of the DC gain versus temperature and perimeter to area ratio indicates that emitter edge current has a major influence on the NDR magnitude. <<ETX>>
The Novel Calcineurin Inhibitor CN585 Has Potent Immunosuppressive Properties in Stimulated Human T Cells*

The Ca2+/calmodulin-dependent protein phosphatase calcineurin is a key mediator in antigen-specific T cell activation. Thus, inhibitors of calcineurin, such as cyclosporin A or FK506, can block T cell activation and are used as immunosuppressive drugs to prevent graft-versus-host reactions and autoimmune diseases. In this study we describe the identification of 2,6- diaryl-substituted pyrimidine derivatives as a new class of calcineurin inhibitors, obtained by screening of a substance library. By rational design of the parent compound we have attained the derivative 6-(3,4-dichloro-phenyl)-4-(N,N-dimethylaminoethylthio)-2-phenyl-pyrimidine (CN585) that noncompetitively and reversibly inhibits calcineurin activity with a Ki value of 3.8 μm. This derivative specifically inhibits calcineurin without affecting other Ser/Thr protein phosphatases or peptidyl prolyl cis/trans isomerases. CN585 shows potent immunosuppressive effects by inhibiting NFAT nuclear translocation and transactivation, cytokine production, and T cell proliferation. Moreover, the calcineurin inhibitor exhibits no cytotoxicity in the effective concentration range. Therefore, calcineurin inhibition by CN585 may represent a novel promising strategy for immune intervention.
Preventing Manets from Blackhole Attack using Blackhole Node Detection Monitoring System

Adhoc networks are prone to number of security threats due to unavailability of centralized authority. It incorporates various malicious activities within the network. This research focuses on single Blackhole attack but our design principles may be applicable to wide range of attacks. So, this proposed approach of Blackhole comprises of active routing misbehavior and forwarding misbehavior. This can be defined by modifying existing DSR protocol with the functionality of single Blackhole node in highly mobile and sparse network without affecting the overall performance of the network.
Reproducibility of neurophysiological and myometric measurement in the ulnar nerve–abductor digiti minimi system

Reliability in strength and neurophysiological measurements is important in evaluating progression of neuromuscular diseases. No data are available on the variability of neurophysiological parameters as compared with maximal voluntary isometric contraction (MVIC) in the same muscles, in healthy subjects. A control population of 26 healthy subjects was studied twice on different days. We evaluated the reliability of neurophysiological parameters obtained from bilateral ulnar nerve stimulation, recording the response over the abductor digiti minimi (ADM) muscle, including distal motor latency, compound muscle potential amplitude and area, F‐wave frequency and mean F‐wave latency, and the derived neurophysiological index that we have described previously. MVIC force was measured in each session in both ADM muscles. The variances between the grouped data obtained in the two recording sessions were identical, indicating a low intrinsic variability with this experimental methodology. Comparison of the mean values obtained in the two sessions revealed no statistically significant differences. The reliability of these neurophysiological and strength measurements in the same nerve/muscle system suggests they may be useful in comparing the dynamics of weakness and neurophysiological change in neuromuscular disease. © 2001 John Wiley & Sons, Inc. Muscle Nerve 24: 1391–1395, 2001
Why Google cannot be the # 1 in Korea?: In Search for Critical Success Factors from Local User Experience

Why foreign companies are not successful in portal business in Korean market? We believe that there are at least three reasons for the phenomenon. First, domestic firms have their own methods and skills to collect users' needs and wants. Second, the domestic firms have efficient internal process of fast implementation. Finally, the role and responsibility of domestic UX teams are rather peculiar to the contexts of domestic internet market. This panel will be presented by the UX professionals from the three major internet portals in Korea. The panel will be presided by the president of Korean Internet Professional Association. Korea Internet Professionals Association, an affiliate of 'Ministry of Science, ICT and Future Planning', which researches Internet technologies, services, planning, design, development, design, promotion, advertising, marketing, analysis, contracting, purchasing, procurement, testing, supervision, evaluation, inspection, management, consulting and education using wired and wireless Internet is a non-profit organization which consists of Internet companies and Internet experts.