Miracle-dz/UniFAR-FTUs huggingface dataset:
An Indoor Smart Lamp For Environments Illuminated Day Time

Lighting energy consumption constitutes % 9-25 of final consumption in buildings. In addition, lights are kept open during daytime in some buildings such as public institutions and schools. The main purpose of this study is to design a remotely controlled smart lamp that measures the illumination of the environment and adjusts illumination level of lamp according to demand in order to decrease the electricity consumption due to lighting during daytime. Also, in this study energy savings that can be achieved with the usage of this lamp in a school building in analyzed. Many studies are conducted to develop smart lamps, however to the authors best knowledge a remotely controlled autonomous smart lamp by Wi-Fi module and a software developed in C# interface, to update required minimum illumination level of the room is not found in literature. By using the developed software minimum illumination levels of the rooms of a whole building can be managed remotely which is useful in cases such as changing the purpose or color of the rooms or changing minimum level seasonally. System consists of Arduino, BH1750 light sensor, strap LEDs, transistors and Wi-Fi module. Daylight illumination level is measured with BH1750. Smart lamp changes its illumination level by taking the difference of measured illumination data from minimum illumination level data, if the measured illumination level is lower than minimum level. In order to analyze the energy saving that could be achieved, illumination level of the indoor and outdoor environment of Faculty of Technology of Selcuk University is measured at 30 minutes’ intervals for one day. Energy saving to be obtained in case of using developed smart lamp is calculated as 1747 kWh/year only for daytimes.
Breeding Biology of Fire-Tailed Myzornis (Myzornis pyrrhoura) In An Alpine Environment In Southwestern China

ABSTRACT We studied the breeding biology of the Fire-tailed Myzornis (Myzornis pyrrhoura) in an alpine environment (3000–3800 m) of the Gaoligong Mountains in southwestern China during its breeding seasons in 2013 and 2014. Nests were built by both sexes and mainly contained moss and rhododendron flakes. They were located on vertical banks or rock faces, about 20–152 cm above the ground. This species was socially monogamous and sexually dimorphic both in plumage pattern and body size. Egg-laying was mainly initiated in mid-April and ended in early July, and the mean date of clutch initiation was 25 April in 2013 (n = 4) and 27 April in 2014 (n =5), respectively. The clutch size averaged 3.00 ± 0.15 (n = 10), and fresh eggs weighed 1.84 ± 0.19 g (n = 11). Males and females made virtually equal contributions in breeding activities, including incubation, provisioning, brooding, and nest sanitation. Incubation lasted for 15 days (n = 2) with a notably high nest attendance (eggs were incubated 99.48% of the time). The total provisioning rates were 6.52 ± 1.82 (range = 3.29–10.29) trips per hour, a rate that did not change significantly throughout the nestling period. Nestlings fledged at 19.67 ± 0.33 (n = 3 nests) days after hatching, when they were 19% heavier than adults. Growth of nestlings met logistic expectations except for tail length. Overall, the reproductive success rate was 42.86%. Compared with other lower-elevation breeding babblers, Myzornis had larger and heavier nests, fewer but larger eggs, and a longer nestling period. These life-history traits may facilitate its reproduction in the cold alpine areas of the Gaoligong Mountains.
What are the characteristics of lionfish and other fishes that influence their association in diurnal refuges?

ABSTRACT In Caribbean reefs, the lionfish Pterois volitans is an invasive species that causes severe negative ecological effects, especially as this crepuscular predator consumes very diverse prey. Lionfish are not active during the day and stay in their refuges, sharing these spaces with various other fishes. The aim of this study is to determine which fishes are associated with the lionfish in their shelters, and what characteristics of both the invasive and native species may influence and explain such coexistence between a predator and its potential prey. Through diving and snorkelling, we visited 141 lionfish refuges, mostly caves, where we observed 204 lionfish and 494 other fish from 16 native species. We recorded species and abundance, as well as lionfish size and abundance. Half of the lionfish were observed in groups and the majority were large-sized. The association with most fish species seems fortuitous, but three species, Gramma loreto, Chromis cyanea and Canthigaster rostrata, were frequently observed in association with lionfish. Numerous fish juveniles, most likely Scarus coeruleus, were also observed together with the invasive predator. The more commonly associated fishes, particularly G. loreto, are mostly associated with large-sized lionfish that were found in groups. The associated fishes are also generally found in groups. Gramma loreto is a potential cleaner of the lionfish; the reasons for the association between these fish species and the invasive lionfish may be more complex than a simple predator-prey relationship and are discussed based on their biological traits and previously reported lionfish trophic ecology and predation behaviour.
Combined effects of rearing and testing temperatures on sperm traits

Temperature experienced during early development can affect a range of adult life‐history traits. Animals often show seemingly adaptive developmental plasticity—with animals reared at certain temperatures performing better as adults at those temperatures. The extent to which this type of adaptive response occurs in gonadal tissue that affects sperm traits is, however, poorly studied. We initially reared male mosquito fish (Gambusia holbrooki) at either 18°C or 30°C, and then measured their sperm reserves as adults. We also looked at the velocity of their sperm, at both the matched and mismatched temperatures. Although males reared at 30°C were larger than those initially reared at 18°C, there was no detectable effect of rearing temperature on absolute sperm number. Sperm swam faster at 30°C than 18°C regardless of the male's rearing temperature. Therefore, we found no evidence of adaptive developmental plasticity. Rearing temperature did, however, significantly influence the relationship between male body size and sperm velocity. Larger males had faster sperm when reared at the warmer temperature and slower sperm when reared at the cooler temperature. This suggests that rearing temperature could alter the relationship between pre‐copulatory sexual selection and post‐copulatory sexual selection as male size affects mating success. Finally, there was a positive correlation between velocities at the two test temperatures, suggesting that temperature experienced during sperm competition is unlikely to affect a male's relative fertilization success.
Candida auris: a latent threat to critically ill patients with COVID-19

1.Centro de Investigaciones Microbiológicas del Cesar (CIMCE), Valledupar, Colombia; 3. Clínica alta complejidad Valledupar, Colombia 3. Clínica Laura Daniela, Valledupar, Colombia, 4.Instituto Cardiovascular del Cesar, Valledupar Colombia. 5. Département de Parasitologie et Mycologie Médicale, Université de Nantes, Nantes Atlantique Universités, EA1155 – IICiMed, Faculté de Pharmacie, Nantes, France 6. Facultad de Medicina, Universidad Nacional de Colombia, Bogotá, Colombia; 7. Clínica Colsanitas, Clínica Universitaria Colombia, Bogotá, Colombia
Photoprocessing of large PAH cations

Abstract In cosmic environments, polycyclic aromatic hydrocarbons (PAHs) strongly interact with vacuum ultraviolet (VUV) photons emitted by young stars. Trapped PAH cations ranging in size from 30 to 48 carbon atoms were irradiated by tunable synchrotron light (DESIRS beamline at SOLEIL). Their ionization and dissociation cross sections were determined and compared with TD-DFT computed photoabsorption cross sections. Evidence for radiative cooling is reported.
Prognostic nutritional index predicts in-hospital mortality in patients with acute Stanford type A aortic dissection

Background: Acute Stanford type A aortic dissection (ATAAD) is a life-threatening medical emergency. The aim of this study was to investigate the clinical significance of the prognostic nutritional index (PNI) as a novel inflammatory marker for ATAAD patients undergoing surgical repair. Methods: We retrospectively examined the medical records of 151 ATAAD patients who treated surgically. Patients were divided into two groups (survival and death) and these groups were compared with respect to clinical and laboratory parameters. The PNI was calculated as 10 × serum albumin (g/dL) + 0.005 × total lymphocyte count (per mm3). Logistic regression analyses were performed to identify the risk factors of in-hospital mortality. Results: The mean age of the study cohort was 61 ± 12 years, 99 (65.6%) were males, and 35 (23.2%) patients died during the hospital stay. The PNI levels were significantly lower in death group compared with survival group (32.80 ± 4.90 vs. 37.94 ± 5.42, p < 0.001). Multivariate analysis showed that the PNI (OR: 0.795, p = 0.005), age (odds ratio [OR]: 1.085, p = 0.034), operating time (OR: 1.660, p = 0.042), and D-dimer (OR: 1.002, p = 0.001) independently predicted in-hospital mortality. The calculated cutoff value of the PNI was 33.01. Conclusion: Lower PNI values are independently associated with in-hospital mortality in ATAAD. The PNI may be a useful tool for predicting the early mortality of ATAAD patients after surgical repair.
Effectiveness of Low Vision Rehabilitation Using Microperimetric Acoustic Biofeedback Training in Patients with Central Scotoma

ABSTRACT Purpose To evaluate the efficacy of visual rehabilitation with microperimeter biofeedback in patients with central scotoma. Materials and Methods 35 consecutive patients with central scotoma (17 age-related macular degeneration (AMD), 14 Stargardt disease, and 4 cone dystrophy) were included in the study. Visual acuity, reading performance by Minnesota Low Vision Reading Test (MNREAD), quality of life by 25-item National Eye Institute Visual Function Questionnaire (NEI VFQ-25), and fixation analysis by MAIA microperimeter were evaluated before and 1 month after training. The rehabilitation program consisted of 10 training sessions of 10 minutes. Results The median best-corrected visual acuity (BCVA) was 0.80 logMAR (range 0.3 to 1.3 logMAR). Fifty-nine percent of patients with AMD developed a preferred retinal locus (PRL) nasal to the fovea, and 64% of the patients with Stargardt disease preferred a PRL superior to the fovea. The PRL location in 3 of 4 cone dystrophy patients was nasal to the fovea. The mean PRL distance from the fovea was 7.57 ± 3.61 degrees. Fixation stability improved with P1 values of 22.34 ± 11.81 versus 32.05 ± 18.79 (p = .003) and 95% bivariate contour ellipse area (BCEA) values of 41.6 versus 23.6 (p = .018) before and after training, respectively. There was a significant difference in reading acuity between before and after training (p = 0.008). The overall score and near activities score of NEI VFQ-25 were found to be increased at the end of the rehabilitation (p < 0.001). Conclusion Rehabilitation with acoustic biofeedback in patients with central scotoma looks like a useful technique for improving fixation stability, reading performance and quality of life.
Mindfulness Training to Improve Nurse Clinical Performance: A Pilot Study

Health care errors are a national concern. Although considerable attention has been placed on reducing errors since a 2000 Institute of Medicine report, adverse events persist. The purpose of this pilot study was to evaluate the effect of mindfulness training, employing the standardized approach of an eight-week mindfulness-based, stress reduction program on reduction of nurse errors in simulated clinical scenarios. An experimental, pre- and post-test control group design was employed with 20 staff nurses and senior nursing students. Although not statistically significant, there were numerical differences in clinical performance scores from baseline when comparing mindfulness and control groups immediately following mindfulness training and after three months. A number of benefits of mindfulness training, such as improved listening skills, were identified. This pilot study supports the benefits of mindfulness training in improving nurse clinical performance and illustrates a novel approach to employ in future research.
Exploring the concerted mechanistic pathway for HIV-1 PR—substrate revealed by umbrella sampling simulation

Abstract HIV-1 protease (HIV-1 PR) is an essential enzyme for the replication process of its virus, and therefore considered an important target for the development of drugs against the acquired immunodeficiency syndrome (AIDS). Our previous study shows that the catalytic mechanism of subtype B/C-SA HIV-1 PR follows a one-step concerted acyclic hydrolysis reaction process using a two-layered ONIOM B3LYP/6-31++G(d,p) method. This present work is aimed at exploring the proposed mechanism of the proteolysis catalyzed by HIV-1 PR and to ensure our proposed mechanism is not an artefact of a single theoretical technique. Hence, we present umbrella sampling method that is suitable for calculating potential mean force (PMF) for non-covalent ligand/substrate-enzyme association/dissociation interactions which provide thermodynamic details for molecular recognition. The free activation energy results were computed in terms of PMF analysis within the hybrid QM(DFTB)/MM approach. The theoretical findings suggest that the proposed mechanism corresponds in principle with experimental data. Given our observations, we suggest that the QM/MM MD method can be used as a reliable computational technique to rationalize lead compounds against specific targets such as the HIV-1 protease.
Caracterização genética de isolados clínicos de Klebsiella pneumoniae resistentes a antibióticos β-lactâmicos de última geração provenientes de Recife-PE

Klebsiella pneumoniae is an enterobacteria associated with serious hospital infections that primarily affects the urinary and respiratory tracts, also causing meningitis and septicaemia, especially in immunocompromised patients. The aim of this study was genetically characterize clinical isolates of K. pneumoniae by the investigation of the βlactams resistance genes blaTEM, blaSHV, blaCTX-M, blaKPC, blaVIM, blaIMP and blaSPM, the plasmid profile and ERIC-PCR. We analyzed 24 isolates from public hospital and from a private hospital from 2007 and 2008, respectively, from the city of Recife-PE. Doubledisk synergy testing, Modified Hodge Test and the MBL E-test were used for phenotypic detection of ESBLs, KPC and MBL, respectively. The blaSHV gene was found in all isolates, blaCTX-M in 62.5% and blaTEM in 29%. The carbapenemases genes blaKPC and blaVIM and were found with a frequency of 71% and 50%, respectively, among the isolates from the private hospital. This is the first report of the gene blaVIM in K. pneumoniae in Recife-PE, Brazil. The genes blaIMP and blaSPM were not detected. The finding that 14 isolates (58%) harboring at least three among the seven β-lactamases genes studied is of concern since it is not often reported. The plasmid profile grouped the 24 isolates in 17 groups and 3 subgroups. The ERIC-PCR classified the isolates in 19 distinct types with 6 isolates exhibiting the same profile, showing clonal relationship. We can concluded that the isolates studied here accumulated resistance determinants which consequently imposes a limitation on the treatment options available, explaining many episodes of failure in the control of many hospital infections.
Comparative effect of Nauclea latifolia leaf fractions on blood glucose and lipid profile parameters of alloxan induced-diabetic rats

The antidiabetic effects of methanol, N-hexane and ethyl acetate leaf fractions of Nauclea latifolia were investigated in diabetic model rats. 150 and 300mg/kg fractions of N. latifolia were administered orally to the experimental animals at two weeks interval, while their blood glucose levels were taken daily. At the end of the experiment, their lipid profiles were assayed using standard methods. The research data indicated significant decreases (P=0.05) of the blood glucose in all the fractions at a dose-dependent manner (ethyl acetate (150 mg/kg = 47.83%; 300 mg/kg = 64.17%), N-hexane (150 mg/kg = 58.45%; 300 mg/kg = 64.18%), methanol (150 mg/kg = 44.5%), except for the 300 mg/kg dose methanol fraction (0.82%) as compared to the increased level in the negative control (33.33%). In the lipid profile assay, there were also a dose dependent significant decrease (P=0.05) of serum Total Cholesterol (TC) and Low Density Lipoprotein (LDL) cholesterol in all the fraction groups (ethylacetate (150 mg/kg- TC = 69.88 ± 8.52 mg/dl, LDL-cholesterol = 8.23±7.76 mg/dl; 300 mg/kg-TC = 51.08±9.93 mg/dl, LDL-cholesterol = 6.44±7.66 mg/dl), N-hexane (150 mg/kg-TC = 73.16 ± 18.62mg/dl, LDL-cholesterol = 33.24±16.19 mg/dl; 300 mg/kg-TC = 69.78±8.41 mg/dl, LDL-cholesterol = 9.29±5.62 mg/dl and methanol (150 mg/kg; TC = 116.86 ± 13.34 mg/dl, LDL-cholesterol = 50.68±14.13 mg; 300 mg/kg-TC = 108.66 ± 12.77 mg/dl, LDL-cholesterol = 42.09±9.93mg/dl) as compared to the high concentration of the negative control group (TC = 383.76 ± 79.68 mg/dl, LDL-cholesterol = 299.46 ± 79.23 mg/dl). Ethylacetate and N-hexane fractions showed significant reductions (P=0.05) of TC and LDL-cholesterol as compared to the positive control (TC=116.36±14.69 mg/dl, LDL-cholesterol = 32.06±13.23mg/dl) also at a dose-dependent manner; thus, portraying a more efficient hypolipidaemic activity than the standard drug. This antidiabetic research on N. latifolia suggest that ethylacetate fraction produces the best effect, followed by N-hexane and lastly by methanol fraction. Key words: Nauclea latifolia, ethyl acetate, n-hexane, methanol, leaf fractions, glibenclamide, antidiabetic, blood glucose, lipid profile.
Technical Note: Extended field‐of‐view (FOV) MRI distortion determination through multi‐positional phantom imaging

Abstract Comprehensive characterization of geometric distortions for MRI simulators and MRI‐guided treatment delivery systems is typically performed with large phantoms that are costly and unwieldy to handle. Here we propose an easily implementable methodology for MR distortion determination of the entire imaging space of the scanner through the use of a compact commercially available distortion phantom. The MagphanRT phantom was scanned at several locations within a MR scanner. From each scan, an approximate location of the phantom was determined from a subset of the fiducial spheres. The fiducial displacements were determined, and a displacement field was fitted to the displacement data using the entire multi‐scan data set. An orthogonal polynomial expansion fitting function was used that had been augmented to include independent rigid‐body transformations for each scan. The rigid‐body portions of the displacement field were thereafter discarded, and the resultant fit then represented the distortion field. Multi‐positional scans of the phantom were used successfully to determine the distortion field with extended coverage. A single scan of the phantom covered 20 cm in its smallest dimension. By stitching together overlapping scans we extended the distortion measurements to 30 cm. No information about the absolute location or orientation of each scan was required. The method, termed the Multi‐Scan Expansion (MSE) method, can be easily applied for larger field‐of‐views (FOVs) by using a combination of larger phantom displacements and more scans. The implementation of the MSE method allows for distortion determination beyond the physical limitations of the phantom. The method is scalable to the user’s needs and does not require any specialized equipment. This approach could open up for easier determination of the distortion magnitude at distances further from the scanner’s isocenter. This is especially important in the newly proposed methodologies of MR‐only simulation in RT and in adaptive replanning in MR linac systems.
A new mixed‐effects regression model for the analysis of zero‐modified hierarchical count data

Count data sets are traditionally analyzed using the ordinary Poisson distribution. However, such a model has its applicability limited as it can be somewhat restrictive to handle specific data structures. In this case, it arises the need for obtaining alternative models that accommodate, for example, (a) zero‐modification (inflation or deflation at the frequency of zeros), (b) overdispersion, and (c) individual heterogeneity arising from clustering or repeated (correlated) measurements made on the same subject. Cases (a)–(b) and (b)–(c) are often treated together in the statistical literature with several practical applications, but models supporting all at once are less common. Hence, this paper's primary goal was to jointly address these issues by deriving a mixed‐effects regression model based on the hurdle version of the Poisson–Lindley distribution. In this framework, the zero‐modification is incorporated by assuming that a binary probability model determines which outcomes are zero‐valued, and a zero‐truncated process is responsible for generating positive observations. Approximate posterior inferences for the model parameters were obtained from a fully Bayesian approach based on the Adaptive Metropolis algorithm. Intensive Monte Carlo simulation studies were performed to assess the empirical properties of the Bayesian estimators. The proposed model was considered for the analysis of a real data set, and its competitiveness regarding some well‐established mixed‐effects models for count data was evaluated. A sensitivity analysis to detect observations that may impact parameter estimates was performed based on standard divergence measures. The Bayesian p ‐value and the randomized quantile residuals were considered for model diagnostics.