Miracle-dz/UniFAR-FTUs huggingface dataset:
Automatic transmission of home blood pressure data can be effective in managing hypertension: a systematic review and meta-analysis

Abstract Aims Home blood pressure telemonitoring (HBPT) is a useful way to manage BP. Recent advances in digital technology to automatically transmit BP data without the patient input may change the approach to long-term BP treatment and follow-up. The purpose of this review is to summarize the latest data on the HBPT with automatic data transmission. Methods and results Articles in English from 1980 to 2021 were searched by electronic databases. Randomized controlled trials comparing HBPT with automatic data transmission with usual BP management and including systolic BP (SBP) and/or diastolic BP (DBP) as outcomes in hypertension patients were included in the systematic review. A meta-analysis was conducted. After removing duplicates, 474 papers were included and 23 papers were identified. The HBPT with automatic data transmission had a significant beneficial impact on BP reduction (mean difference for office SBP −6.0 mm Hg; P < 0.001). Subgroup analyses showed that the studies using smartphone applications reduced BP significantly more in the intervention group than in the control group (standardized mean difference for office and home SBP −0.25; P = 0.01) as did the studies using HBPT other than the applications. Longer observation periods showed a sustained effect, and multidisciplinary cooperation was effective. Conclusion This review suggests that a care path based on HBPT with automatic data transmission can be more effective than classical management of hypertension. In particular, the studies using smartphone applications have shown beneficial effects. The results support the deployment of digital cardiology in the field of hypertension management.
Transcriptome Analysis Reveals Critical Genes and Pathways in Carbon Metabolism and Ribosome Biogenesis in Poplar Fertilized with Glutamine

Exogenous Gln as a single N source has been shown to exert similar roles to the inorganic N in poplar ‘Nanlin895′ in terms of growth performance, yet the underlying molecular mechanism remains unclear. Herein, transcriptome analyses of both shoots (L) and roots (R) of poplar ‘Nanlin895’ fertilized with Gln (G) or the inorganic N (control, C) were performed. Compared with the control, 3109 differentially expressed genes (DEGs) and 5071 DEGs were detected in the GL and GR libraries, respectively. In the shoots, Gln treatment resulted in downregulation of a large number of ribosomal genes but significant induction of many starch and sucrose metabolism genes, demonstrating that poplars tend to distribute more energy to sugar metabolism rather than ribosome biosynthesis when fertilized with Gln-N. By contrast, in the roots, most of the DEGs were annotated to carbon metabolism, glycolysis/gluconeogenesis and phenylpropanoid biosynthesis, suggesting that apart from N metabolism, exogenous Gln has an important role in regulating the redistribution of carbon resources and secondary metabolites. Therefore, it can be proposed that the promotion impact of Gln on poplar growth and photosynthesis may result from the improvement of both carbon and N allocation, accompanied by an efficient energy switch for growth and stress responses.
Foliarly Applied 24-Epibrassinolide Modulates the Electrical Conductivity of the Saturated Rhizospheric Soil Extracts of Soybean under Salinity Stress

The accumulation of salts within the rhizosphere is a common phenomenon in arid and semi-arid regions where irrigation water is high in salts. A previous study established the ameliorative effect of foliarly applied 24-epibrassinolide (BR) on soybean under salinity stress. As a follow-up to that study, this work evaluated the effects of BR on the electrical conductivity of saturated soil extracts (ECses) under soybean exposed to salt stress. Three salinity levels (3.24, 6.06 and 8.63 dS/m) in a factorial combination with six frequencies of BR application—control, seedling, flowering, podding, seedling + flowering and seedling + flowering + podding—were the treatments, and the rhizospheric ECse was monitored from 3 to 10 weeks after the commencement of irrigation with saline water (WAST). The principal component analysis revealed that samples in saline BR treatments clustered together based on the BR application frequencies. There was a significant increase in ECse with increases in salinity and WAST. The frequent application of BR significantly reduced ECse to 5.07 and 4.83 dS/m relative to the control with 6.91 dS/m, respectively, at week 10. At 8.63 dS/m, the application of BR (seedling + flowering + podding) reduced ECse by 31.96% compared with the control. The underlining mechanism is a subject for further investigation.
Investigation of image noise in cone-beam CT imaging due to photon counting statistics with the Feldkamp algorithm by computer simulations

Cone beam CT (CBCT) imaging technique has found many applications in medical imaging in recent years since it provides three-dimensional image reconstruction with low contrast detectability and high resolution. In CBCT systems, image noise caused by photon counting statistics plays an important role in image quality by affecting low contrast detection and patient dose. In this paper, we studied image noise caused by photon counting statistics with the Feldkamp's cone beam reconstruction algorithm. A noise model based on photon counting detector was developed to provide the noise distribution in 3D image space and the quantitative relationships between image noise level and various CT parameters, including the exposure level, the number of projections, the reconstruction filter and the detector pixel size. Computer simulations of a spherical water phantom were conducted to test the theoretical model. This work provides the noise spatial distribution in cone-beam CT and its relationship with CBCT parameters. It can also provide local noise information for adaptive de-noising in the future.
Multi‐Fluid MHD Simulations of Europa's Plasma Interaction: Effects of Variation in Europa's Atmosphere

Europa's plasma interaction is inextricably coupled to its O2 atmosphere by the chemical processes that generate plasma from the atmosphere and the sputtering of magnetospheric plasma against Europa's ice to generate O2. Observations of Europa's atmosphere admit a range of possible densities and spatial distributions (Hall et al., 1998, https://doi.org/10.1086/305604). To better understand this system, we must characterize how different possible configurations of the atmosphere affect the 3D magnetic fields and bulk plasma properties near Europa. To accomplish this, we conducted a parameter study using a multi‐fluid magnetohydrodynamic model for Europa's plasma interaction (Harris et al., 2021, https://doi.org/10.1029/2020ja028888). We varied parameters of Europa's atmosphere, as well as the conditions of Jupiter's magnetosphere, over 18 simulations. As the scale height and density of Europa's atmosphere increase, the extent and density of the ionosphere increase as well, generating strong magnetic fields that shield Europa's surface from impinging plasma on the trailing hemisphere. We also calculate the precipitation rate of magnetospheric plasma onto Europa's surface. As the O2 column density increased from (1–2.5) × 1014 cm−2, the precipitation rate decreased sharply then leveled off at 2 × 1024 ions/s for simulations with low magnetospheric plasma density and 6.4 × 1024 ions/s for simulations with high magnetospheric plasma density. These results indicate that the coupling between Europa's plasma populations and its atmosphere leads to feedback that limits increases in the ionosphere density.
Prolonged Hyperglycemia Causes Visual and Cognitive Deficits in Danio rerio

The present study induced prolonged hyperglycemia (a hallmark symptom of Type 2 diabetes [T2DM]) in Danio rerio (zebrafish) for eight or twelve weeks. The goal of this research was to study cognitive decline as well as vision loss in hyperglycemic zebrafish. Fish were submerged in glucose for eight or twelve weeks, after which they were assessed with both a cognitive assay (three-chamber choice) and a visual assay (optomotor response (OMR)). Zebrafish were also studied during recovery from hyperglycemia. Here, fish were removed from the hyperglycemic environment for 4 weeks after either 4 or 8 weeks in glucose, and cognition and vision was again assessed. The 8- and 12-week cognitive results revealed that water-treated fish showed evidence of learning while glucose- and mannitol-treated fish did not within the three-day testing period. OMR results identified an osmotic effect with glucose-treated fish having significantly fewer positive rotations than water-treated fish but comparable rotations to mannitol-treated fish. The 8- and 12-week recovery results showed that 4 weeks was not enough time to fully recovery from the hyperglycemic insult sustained.
Liposomal Delivery of Newly Identified Prophage Lysins in a Pseudomonas aeruginosa Model

Pseudomonas aeruginosa is a Gram-negative opportunistic bacterium that presents resistance to several antibiotics, thus, representing a major threat to human and animal health. Phage-derived products, namely lysins, or peptidoglycan-hydrolyzing enzymes, can be an effective weapon against antibiotic-resistant bacteria. Whereas in Gram-positive bacteria, lysis from without is facilitated by the exposed peptidoglycan layer, this is not possible in the outer membrane-protected peptidoglycan of Gram-negative bacteria. Here, we suggest the encapsulation of lysins in liposomes as a delivery system against Gram-negative bacteria, using the model of P. aeruginosa. Bioinformatic analysis allowed for the identification of 38 distinct complete prophages within 66 P. aeruginosa genomes (16 of which newly sequenced) and led to the identification of 19 lysins of diverse sequence and function, 5 of which proceeded to wet lab analysis. The four purifiable lysins showed hydrolytic activity against Gram-positive bacterial lawns and, on zymogram assays, constituted of autoclaved P. aeruginosa cells. Additionally, lysins Pa7 and Pa119 combined with an outer membrane permeabilizer showed activity against P. aeruginosa cells. These two lysins were successfully encapsulated in DPPC:DOPE:CHEMS (molar ratio 4:4:2) liposomes with an average encapsulation efficiency of 33.33% and 32.30%, respectively. The application of the encapsulated lysins to the model P. aeruginosa led to a reduction in cell viability and resulted in cell lysis as observed in MTT cell viability assays and electron microscopy. In sum, we report here that prophages may be important sources of new enzybiotics, with prophage lysins showing high diversity and activity. In addition, these enzybiotics following their incorporation in liposomes were able to potentiate their antibacterial effect against the Gram-negative bacteria P. aeruginosa, used as the model.
Likelihood ratio in estimating gamma distribution parameters

Abstract The Gamma Distribution is widely used in Engineering and Industrial applications.Estimation of parameters is revisited in the two-parameter Gamma distribution. Theparameters are estimated by minimizing the likelihood ratios. A comparative study be-tween the method of moments, the maximum likelihood method, the method of productspacings, and minimization of three di erent likelihood ratios is performed using simula-tion. For the scale parameter, the maximum likelihood estimate performs better and forthe shape parameter, the product spacings estimate performs better. Among the threelikelihood ratio statistics considered, the Anderson-Darling statistic has inferior per-formance compared to the Cramer-von-Misses statistic and the Kolmogorov-Smirnovstatistic.Keywords: Di-gamma function, grid search method. 1. Introduction The random variable Xhas a Gamma distribution with two parameters and if it hasa probability density function of the form:f(x; ; ) =x 1 e x= ( ) ; >0; >0; (1:1)where is known as the shape parameter and as the scale parameter. The distributionfunction of the Gamma distribution (1.1) can be written asF(x; ; ) =Z
Effects of Different Ratios of Carbohydrate–Fat in Enteral Nutrition on Metabolic Pattern and Organ Damage in Burned Rats

(1) Background: Nutritional support is one of the most important cornerstones in the management of patients with severe burns, but the carbohydrate-to-fat ratios in burn nutrition therapy remain highly controversial. In this study, we aimed to discuss the effects of different ratios of carbohydrate–fat through enteral nutrition on the metabolic changes and organ damage in burned rats. (2) Methods: Twenty-four burned rats were randomly divided into 5%, 10%, 20% and 30% fat nutritional groups. REE and body weight were measured individually for each rat daily. Then, 75% of REE was given in the first week after burns, and the full dose was given in the second week. Glucose tolerance of the rats was measured on days 1, 3, 7, 10 and 14. Blood biochemistry analysis and organ damage analysis were performed after 7 and 14 days of nutritional therapy, and nuclear magnetic resonance (NMR) and insulin content analysis were performed after 14 days. (3) Results: NMR spectra showed significant differences of glucose, lipid and amino acid metabolic pathways. The energy expenditure increased, and body weight decreased significantly after burn injury, with larger change in the 20%, 5% and 30% fat groups, and minimal change in the 10% fat group. The obvious changes in the level of plasma protein, glucose, lipids and insulin, as well as the organ damage, were in the 30%, 20% and 5% fat groups. In relative terms, the 10% fat group showed the least variation and was closest to normal group. (4) Conclusion: Lower fat intake is beneficial to maintaining metabolic stability and lessening organ damage after burns, but percentage of fat supply should not be less than 10% in burned rats.
Point-Group Theory Tables

Preface. 0: How to use this book. 1: Introduction. 2: Basic group theory: definitions and formulae. 3: Parametrization of symmetry operations. 4: Symmetry operations: notation and properties. 5: Notation for point groups, single and double. 6: Derivation of the proper and improper point groups. 7: Direct product, semidirect product and coset expansion forms of the point groups. 8: The crystallographic point groups. 9: Group chains. 10: Double groups. Spinor and projective representations. 11: The matrices of SU(2) and SU'(2). 12: The continuous groups. Rotations, their matrices, and the irreducible representations of O(3). 13: Bases: spherical harmonics, spinors, cartesian tensors, and the functions s, p, d, f. 14: Notation for the irreducible representations. 15: Stereographic projections and three-dimensional drawings of point groups. 16: How to use the tables. 17: Problems. References. The Tables
The Influence of the Role of Village Apparatus, Competence of Village Fund Management Apparatus and Government Internal Control System on Village Fund Management Accountability (Study on Villages in Kumelembuai District)

This study aims to determine the effect of the role of the village apparatus, the competence of the village fund management apparatus, and the government's internal control system either partially or simultaneously on the accountability of village fund management in Kumelembuai District. This type of research is quantitative research with data collection methods, namely questionnaires filled out by respondents with a population of 101 and all of them are used as research samples. The data analysis method used was multiple linear regression using IBM SPSS 26. The results of this study shows that the government's internal control system has a positive and significant effect on the accountability of village fund management, while the role of village officials and the competence of the village fund management apparatus partially does not affect the accountability of village fund management.
A Review of Stimuli-Responsive Smart Materials for Wearable Technology in Healthcare: Retrospective, Perspective, and Prospective

In recent years thanks to the Internet of Things (IoT), the demand for the development of miniaturized and wearable sensors has skyrocketed. Among them, novel sensors for wearable medical devices are mostly needed. The aim of this review is to summarize the advancements in this field from current points of view, focusing on sensors embedded into textile fabrics. Indeed, they are portable, lightweight, and the best candidates for monitoring biometric parameters. The possibility of integrating chemical sensors into textiles has opened new markets in smart clothing. Many examples of these systems are represented by color-changing materials due to their capability of altering optical properties, including absorption, reflectance, and scattering, in response to different external stimuli (temperature, humidity, pH, or chemicals). With the goal of smart health monitoring, nanosized sol–gel precursors, bringing coupling agents into their chemical structure, were used to modify halochromic dyestuffs, both minimizing leaching from the treated surfaces and increasing photostability for the development of stimuli-responsive sensors. The literature about the sensing properties of functionalized halochromic azo dyestuffs applied to textile fabrics is reviewed to understand their potential for achieving remote monitoring of health parameters. Finally, challenges and future perspectives are discussed to envisage the developed strategies for the next generation of functionalized halochromic dyestuffs with biocompatible and real-time stimuli-responsive capabilities.
Attitudes of Polish adolescents towards energy drinks. Part 2. Are these attitudes associated with energy drink consumption?

INTRODUCTION AND OBJECTIVE In recent years, researchers have pointed to the growing popularity of energy drinks (EDs) in adolescents. This is a worrying trend due to the fact that energy drink (ED) consumption in this age group poses health risks. Among factors that could predict ED consumption, are attitudes towards EDs. The aim of the study was to identify attitudes towards EDs, and to investigate associations between these attitudes and ED consumption behaviours. The study also aimed to assess whether attitudes and ED consumption behaviours were differentiated by variables, such as gender, stage of education, socio-economic status and academic achievement. MATERIAL AND METHODS The study was conducted among adolescents aged 13-19 years living in the Pomeranian Province (northern Poland). An anonymous questionnaire with a scale to identify attitudes towards EDs was used in the study. Results were assessed as statistically significant at p ≤ 0.05. RESULTS According to the results, 2/3 of the surveyed adolescents consumed EDs. Boys, high school students and students with poorer academic achievement consumed EDs more often than girls, middle school students and very good students. The adolescents preferred a single ED intake at the level of 250 mL. The distribution of the results in this regard was differentiated by gender and academic achievement. The prevailing percentage of the respondents had ambivalent attitudes towards EDs. It was found that negative attitudes towards EDs were expressed by a higher percentage of the girls and the very good students. Positive attitudes towards EDs were associated with frequent ED consumption and with a high level of single ED intake. CONCLUSIONS The results allow the conclusion that attitudes towards EDs identified in the studied sample can be considered an important factor related to ED consumption behaviorus.
Modification of semiconducting copper oxide thin films using ion implantation

The article describes method of Cr + ion implantation with energy of 10 keV and 15 keV. This method can be used to modify thin film semiconductors. Simulations of implantation process were performed using the Stopping and Range of Ions in Matter software, taking into account different energies of the ion beam. The apparatus diagrams of ion implantation and magnetron sputtering processes are presented. Optical and structural properties of non-implanted and implanted Cu 4 O 3 and CuO films were studied. by
The Use of Web Technology and IoT to Contribute to the Management of Blood Banks in Developing Countries

Health-care-sector-related activities are more accessible and faster as a result of technological development. Technology such as the Internet of Things (IoT) can work with blood bank services to manage and provide healthy blood in emergencies. However, there are many problems in blood bank management and inventory monitoring, especially in developing countries as compared to developed ones. The lack of an adequate and safe blood supply is a major limitation to health care in the developing world. The instability of the electric power in developing countries may lead to a temperature departure from the recommended for keeping blood inventory, and the use of manual systems, which are characterized by time and resource exhaustion and human mistakes, augments the management problems. This study aims to introduce a reliable, practical application to manage and organize the blood bank, manage donor information, monitor inventory, and obtain matching blood types as quickly as possible. The proposed system was designed and implemented in two parts: using Web technology for enhanced data management and using an IoT sensor for blood inventory temperature monitoring in real time. The test stage helped us to measure the Web application’s functionality with sensors, and the results were encouraging. Obtaining and monitoring blood bank data were made easier in real time by using the black box method for functionalities testing. The evaluation step was performed using a questionnaire instrument based on three parameters: Satisfaction, Effectiveness, and Efficiency. The questionnaire was answered by 22 participants working in the blood bank management field. The results indicated that end users generally responded positively to the system which improved blood bank administration and services. This indicated efficiency of the application and the desire to adopt it. Integrating the two technologies can enhance usability and applicability in the health care sector.
Associations between Schizotypal Facets and Symptoms of Disordered Eating in Women

Research has suggested that schizotypy—a personality organisation representing latent vulnerability for schizophrenia-spectrum disorders—may be elevated in women with symptoms of disordered eating. However, studies have not fully considered associations between symptoms of disordered eating and multidimensional schizotypy. To overcome this limitation, we asked an online sample of 235 women from the United States to complete measures of symptoms of disordered eating (drive for thinness, body dissatisfaction, and bulimic symptoms) and multidimensional schizotypy. Correlational analyses indicated significant associations between drive for thinness and bulimic symptoms, respectively, and most schizotypal facets. Body dissatisfaction was significantly associated with only two schizotypal facets. Overall, the strength of correlations was weak-to-moderate. Regression results indicated that only the schizotypal feature of excessive social anxiety was significantly associated with all risk for disordered eating factors. These results are consistent with aetiological models of disordered eating that highlight socio-affective difficulties as risk factors for symptoms of disordered eating.
The Process of Test the Single-factor Capital Asset Pricing Model

The primary purpose is to test the Single-factor Capital Asset Pricing Model (CAPM) based on the Australian stock exchange market. At the same time, previous research explained the limitations and shortcomings of the Single-factor CAPM model and briefly introduced the optimization and change of the CAPM. This paper also points out whether investors and researchers can continue to use Treasury bonds as risk-free assets based on the high inflation rate in the United States.