Miracle-dz/UniFAR-FTUs huggingface dataset:
Photosensitizer-based multimodal PSMA-targeting ligands for intraoperative detection of prostate cancer

Incomplete resection of prostate cancer (PCa) occurs in 15%-50% of PCa patients. Disease recurrence negatively impacts oncological outcome. The use of radio-, fluorescent-, or photosensitizer-labeled ligands to target the prostate-specific membrane antigen (PSMA) has become a well-established method for the detection and treatment of PCa. Methods: Here, we developed and characterized multimodal [111In]In-DOTA(GA)-IRDye700DX-PSMA ligands, varying in their molecular composition, for use in intraoperative radiodetection, fluorescence imaging and targeted photodynamic therapy of PCa lesions. PSMA-specificity of these ligands was determined in xenograft tumor models and on fresh human PCa biopsies. Results: Ligand structure optimization showed that addition of the photosensitizer (IRDye700DX) and additional negative charges significantly increased ligand uptake in PSMA-expressing tumors. Moreover, an ex vivo incubation study on human tumor biopsies confirmed the PSMA-specificity of these ligands on human samples, bridging the gap to the clinical situation. Conclusion: We developed a novel PSMA-targeting ligand, optimized for multimodal image-guided PCa surgery combined with targeted photodynamic therapy.
Population balance modeling of a microalgal culture in photobioreactors: Comparison between experiments and simulations

The growth of Scenedesmus obliquus in photobioreactors was both experimentally investigated and numerically simulated by solving a population balance equation (PBE), accounting for cell growth and division. The PBE is solved using the Finite size domain Complete set of trial functions Method Of Moments (FCMOM) and a wide range of operative conditions, namely both a batch and a continuous reactor under different light intensities, were considered in the experiments and in the numerical simulations. A thorough validation of the mathematical model was performed by comparing the experimental temporal profiles and steady-state values of the cell density, wet weight, cell average mass, and mass distributions of the microalgal culture with the corresponding simulation results. The parameters of the distribution of division mass were identified to fit the experimental data; specifically, from the continuous reactor data, the dependence of the mean division mass from the cell average mass was obtained. © 2015 American Institute of Chemical Engineers AIChE J, 61: 2702–2710, 2015
COMPARISON OF SYMMETRIC AND ASYMMETRIC GARCH MODELS IN THE FUTURES CONTRACT OF ROBUSTA COFFEE IN JAKARTA FUTURES EXCHANGE

Futures exchange is growing rapidly in various countries and has become one of the supports for the economic development of the country. However, research on investment in this field in Indonesia is limited. This study compares the symmetric and asymmetric GARCH models to investigate the volatility of the futures price data of Robusta coffee in the Jakarta Futures Exchange. It used the GARCH, EGARCH, and GJR-GARCH models. Meanwhile, the data used were robusta coffee prices, covering spot prices, March contract prices, and September contract price for the 2016-2019 period. The results of the study indicate that the GARCH (1,1) is the most suitable model for the three Robusta coffee prices.
Elementary and Middle School Children's Comprehension of Euclidean Transformations.

A recurring question of interest to curriculum writers and mathematics educators is the following: "What geometry should be taught in the elementary and middle schools, at what age, and in what context? " Substantive recommendations for the inclusion of transformational geometry in the elementary and middle school curriculum have been made and are being implemented. However, there is a scarcity of research data on which to base these innovations. More specifically, little empirical evidence exists concerning the spatial capability of children with respect to Euclidean transformations. Hence, the present study was devised to investigate 9, 11, and 13 year-old children's comprehension of Euclidean transformations; that is, to investigate their ability to form a mental image of a planar figure, to perform a mental operation (a Euclidean transformation) on this representation, and then to construct the resultant in correct position. In formulating the study, primary consideration was given to the structure of geometry and to a comparison of this structure with what is known about the cognitive structure of the elementary and middle school child. Klein's principle, with its emphasis on transformations, invariants under transformations, and groups of transformations concisely revealed the structure of geometry. The developmental theory of Jean Piaget was used to examine the child's cognitive development.
Time Optimization of Dielectric Response Measurements

Determination of moisture in paper and pressboard of HV apparatus insulation is a feature of dielectric response method. Dielectric spectroscopy in frequency (FDS) and in time (PDC and RVM) domain are forms of dielectric response measurements. However one disadvantage of this method is the time consuming procedure. It takes several hours and shorter procedures give information only with lower accuracy. In this paper is shown that the transformation of data from time domain gives frequency domain data with sufficient accuracy in the low frequency range. Hamon has shown that with the data of polarization current at a time t the dielectric loss at a frequency f=0.1/t can be calculated. This means data of 1000s represent data of 0.1mHz. The proposed measurements of dielectric response are performed from 1kHz to 10mHz with FDS method and from 1s to 1000s with PDC method. This saves time of dielectric measurements and gives reliable data for the determination of the moisture content of solid insulation too.
Grid Tied Solar Photovoltaic Power Plants with Constant Power Injection Maximum Power Point Tracking Algorithm

Received: 16 March 2020 Accepted: 28 July 2020 Day to day there is an increase in installations of new Solar Photovoltaic Power plants (SPVPP’s) which directly reflects the grid. As the SPVPP’s output power is fluctuating in nature, which is directly injected to the utility grid faces the challenges like overloading. Therefore, to overcome the overloading situations of grid, its infrastructure should be replaced by higher ratings which will increase the system cost. Due to this there is a need to limit the grid injected power from SPVPP’s to overcome the overloading situations. In this article a Constant power injection (CPI) algorithm is used to control the feed in power to grid as per grid regulations. Based on the instantaneous SPVPP’s output power and power limiting value this strategy will controls the output power by switching between the incremental conductance maximum power point tracking (InC-MPPT) algorithm and CPI algorithm. The proposed InC-CPI algorithm is applied to the single phase two-stage (SPTS) systems with the working region is on the left side of maximum power point (MPP) for maintaining the system to be in stable conditions. In this article the InC-CPI and the perturb and observe (P&O)-CPI algorithms were compared, and results were analyzed. The proposed control algorithm is designed using Matlab/Simulink and the results taken for both clear and cloudy days with wide varying climatic conditions.
Some recent measurements of H2S oxidation rates and their implications to atmospheric chemistry

The general belief that significant fractions of atmospheric sulfur are donated naturally from the earth's surface in the form of hydrogen sulfide and/or its organic homologs implies that atmospheric breakdown of these materials must be a rather fast process. It has been expected that oxidation of these materials by atmospheric ozone should contribute significantly in accomplishing this breakdown; and experimental measurements have been published which do, indeed, indicate rapid ozone oxidation rates, corresponding to lifetimes of the order of hours under typical tropospheric conditions. This paper discusses some later experimental measurements on H 2 S ozone reaction rates which disagree with former determinations, predicting typical H 2 S lifetimes of the order of months—much too long for this reaction to be a significant mechanism of atmospheric removal. The results also indicate the H 2 S ozone reaction should be expected to proceed homogeneously in the atmosphere, with catalytic effects being of little or no importance. The reaction proceeds thermally; light in the visible region does not affect its rate appreciably. These measurements indicate that some mechanism(s) other than ozonation must be responsible for atmospheric breakdown of reduced sulfur compounds. Final portions of the paper examine some possibilities for these mechanisms. DOI: 10.1111/j.2153-3490.1974. tb01978.x
Family-work conflict and safety performance: An un-examined relationship in the Ghanaian mining industry

Purpose – Studies on family-work conflict and job performance have received much attention. However, there are still unanswered questions about how family-work conflict affects specific job performance, such as safety performance. Therefore, this current study attempted to investigate the extent to which family-work conflict affects two kinds of safety performance, such as safety compliance and safety participation through the mediating role of job stress. Design/methodology/approach –We developed a model that examined family-work conflict as the independent variable, job stress as a mediator variable, and safety compliance and safety participation of safety performance as the dependent variables. Using a questionnaire survey, we gathered 302 valid responses from contract mineworkers in Tarkwa, Ghana. We analysed the hypothesised relationships using the structural equation model. Findings – From the results of our study, family-work conflict had a significant negative and positive effect on safety compliance and safety participation, respectively. Job stress also had a significant negative influence on safety compliance and safety participation. Furthermore, testing job stress as a mediator revealed that job stress could act as a partial mediator in the relationship between family-work conflict and all two dimensions of safety performance. Originality/value –This current study is vital for managerial practices. Also, the structural model presents a different perspective on the impact of family-work conflict on safetyrelated issues.
On the theory of thin rotating jets: A quasi‐geostrophic time dependent model

The time‐dependent meandering in a thin baroclinic jet over bottom topography is discussed in the quasi‐geostrophic approximation. The motion of the axis of the jet is taken to be vertically coherent and the axis itself is defined as inextensible. The motion is examined from a frame of reference moving with the axis but fixed at an arbitrary longitude in terms of an open ocean spatial initial value problem. The velocities of the axis and of the jet are quasi‐geostrophic, and vorticity conservation for the first non‐geostrophic components constrains the evolution of the axis and gives a path equation. The spatial linearized stability problem is studied and the jet is found to be baroclinically unstable to path disturbances of sufficiently high frequency which amplify downstream. An exact solution is obtained to the nonlinear path equation over a flat bottom with no s‐effect. The evolution of the path of these unstable meanders is such that the path closes itself and forms rings (at which point the analysis.
Changing Morphology and Crystal Structure in Ettringite by Trivalent Chromium

Recently, solidification processing by cement material of waste that isn’t only increasing but also study is now in progress. Ettringite(Ca6[Al(OH)6]2(SO4)3•26H2O), which is a hydration product of calcium aluminate minerals is highly effective at immobilizing heavy metallic ions through a substitution mechanism. An aqueous solution containing calcium hydroxide, aluminum sulfate, and CrCl3(trivalent chromium) was subjected to irradiate by ultrasonic irradiation under atmospheric pressure to investigate its effect on the synthesis of Cr(III)-ettringite. The verified XRD (100) peak tended to shift to the left and changed morphology as CrCl3 input.
Improving the Electrochemical Performance of SnO2 Cathodes in Lithium Secondary Batteries by Doping with Mo

Small-grain SnO{sub 2}, SnO{sub 2}/Mo (2%), and SnO{sub 2}/Mo (30%) samples were prepared by using low-temperature aqueous methods and tested as cathodes in secondary lithium batteries. Cells were cycled between 1.0 and 0.0 V. The best electrochemical performance was obtained from the Li/[SnO{sub 2}/Mo (2%)] cell, which retained 87% of its initial capacity (510 mAh/g) after 50 cycles; by contrast, the Li/SnO{sub 2} cell only retained 60% of its initial capacity (570 mAh/g). Significantly increased Mo contents caused the capacity to fade drastically.
A Study of L-Lactide Ring-Opening Polymerization Kinetics

The paper presents an experimental study of L-lactide polymerization in molten state using as initiator the Stannous Octoate. The experiments were performed in a Haake mixer. The operating temperatures were between 170 and 195°C, the reaction time up to 60 min and monomer to initiator initial molecular ratio between 10 2 and 5.10 3 . The conversion was determined by using 1 H NMR and the molecular weights distributions by SEC. A preliminary mathematical modeling study was also performed, based on experimental data and a previously published reaction scheme.
Temperature Dependence of the Static Relative Permittivity of Octylcyanobiphenyl (8CB)

Abstract Measurements of the relative static permittivity e of octylcyanobiphenyl (8CB) in the smectic A, the nematic and the isotropic phases between 22°C and 140°C are reported. The resolution of the measurements was better than 0.01% and the temperature stability was better than 0.01 °C. Detailed measurements have been carried out near the AN and NI transitions. For the AN transition. no discontinuity in e|| or e| was observed, which is consistent with the second-order nature of this transition in 8CB. From the dielectric anisotropy in the N-phase, a critical exponent β ≃ 0.25 was obtained for the temperature dependence of the order parameter. This value of β is in support of the hypothesis of quasi-tricriticality for this transition. In the isotropic phase of 8CB, a pretransitional anomalous maximum in e was observed near T N1- The same effect was also measured for two other materials with cyano-end groups (undecylcyanobiphenyl and pentylcyanophenylcyclohexane). For two compounds without a cyano-end g.
Bis(carbene)pyridine Complexes of the Early to Middle Transition Metals: Survey of Ethylene Oligomerization and Polymerization Capability

Bis(carbene)pyridines of the type 2,6-bis(1-(alkyl/aryl)imidazol-2-ylidene)pyridine have been complexed to Ti, V, Cr, Fe, and Co and single-crystal X-ray structures obtained for two of the complexes (M = Cr, Fe). The structures confirm the tight chelate bite angles (ca. 76−79°) enforced by this ligand. All complexes have been evaluated as catalysts for ethylene oligomerization and polymerization in combination with a variety of cocatalysts. While Ti and V complexes of this ligand give rise to highly active ethylene polymerization catalysts, Cr complexes produce exceptionally active Schulz−Flory oligomerization catalysts in combination with MAO. In contrast, complexes of Fe and Co are inactive, and possible reasons for this are suggested.
Explosive oxidation of hydrogen sulphide: self-heating, chain-branching and chain-thermal contributions to spontaneous ignition

The spontaneously explosive oxidation of hydrogen sulphide in a 290 cm3 vessel has been in-vestigated over a temperature range 280–360°C and between pressures of 10 and 120 mmHg. Conditions for ignition have been mapped on a p,T diagram. Very fine thermocouples (25 µm Pt–Pt/Rh) have been used to detect and measure self-heating, and special emphasis has been laid on the direct measurement of the size and form of the temperature against time histories for different initial conditions or locations on the ignition diagram. The effects of reactant proportions and of added diluents (with different thermal conductivities) on the second and third ignition limits have also been studied.Although the reaction exhibits many features traditionally associated with purely branched chain explosions, the direct temperature measurements have revealed extensive self-heating under very varied conditions of pressure and temperature. Boundaries may be drawn on the ignition diagram that separate the regions where a combined chain-thermal mechanism is responsible for explosions (I) from those which may be considered as purely thermal (II) or isothermal branched chain (III) in nature.The measured temperature against time histories provide novel experimental support for the unified theoretical treatment of chain and thermal explosions of Gray and Yang. Critical temperature rises are smaller than would be expected on a purely thermal basis, and induction times are longer. In the chain-thermal region, the rate of self-heating immediately prior to ignition is not always rapid; indeed, temperature excesses may be relatively steady or even decreasing when spontaneous explosion takes place. We should expect similar behaviour in the hydrogen-oxygen reaction.
An Experimental Study of Structured Packing in High Pressure Services

Both distillation performance and hydrodynamic study for backmixing by tracer technique were carried out in a high-pressure packed column with 0.15 m inner diameter over a wide range of operating conditions. Isobutane and n-pentane are employed as test mixture in the distillation experiment and air/water is used for the hydrodynamic study. The column is installed with Mellapak 350Y structured packing and the total packing height is 2.0 m. With the increasing operating pressure, the separation efficiency increases slightly while the F-factor corresponding to the maximum efficiency at each pressure is descending. It is noted that, at all operating pressures, with the increase of F-factor, the packing efficiency is slightly higher up to the flooding point. The application of SRP model to high-pressure distillation gives much lower values of HTUOG than those obtained experimentally. An additional term, the height of mixing unit, is introduced to correct the SRP model and improve its accuracy at high pressure. From the tracer experiments, the height of mixing unit for gas phase was found to be larger than that for the liquid phase. From this viewpoint, it is believed that the gas phase backmixing gives more unfavorable influence on the separation efficiency in comparison with liquid phase.
Physical Exertion and Mental Performance

The problem of why people in a state of fatigue make wrong decisions prompted a series of laboratory experiments of which two are described. Subjects pedalled a bicycle ergometer for varying periods of time and were tested for mental performance after different amounts of physical exertion. The results showed that a sub-maximal amount of physical exertion improved mental performance on the Brown and Poulton test of attention which relies heavily on short term memory. When the exertion was increased over longer periods of time the graph showing the relationship of mental performance to physical exertion followed the form of an inverted U. The evidence suggests that physical exertion affects mental performance by raising the level of arousal. Areas for further research are suggested.
Hyperbranched homo and thermoresponsive graft copolymers by using ATRP‐macromonomer initiators

Macromonomer initiators behave as macro cross-linkers, macro initiators, and macromonomers to obtain branched and cross-linked block/graft copolymers. A series of new macromonomer initiators for atom transfer radical polymerization (MIM-ATRP) based on polyethylene glycol (Mn = 495D, 2203D, and 4203D) (PEG) were synthesized by the reaction of the hydroxyl end of mono-methacryloyl polyethylene glycol with 2-bromo propanoyl chloride, leading to methacryloyl polyethylene glycol 2-bromo propanoyl ester. Poly (ethylene glycol) functionalized with methacrylate at one end was reacted with 2-bromopropionyl chloride to form a macromonomeric initiator for ATRP. ATRP was found to be a more controllable polymerization method than conventional free radical polymerization in view of fewer cross-linked polymers and highly branched polymers produced from macromonomer initiators as well. In another scenario, ATRP of N-isopropylacrylamide (NIPAM) was initiated by MIM-ATRP to obtain PEG-b-PNIPAM branched block/graft copolymers. Thermal analysis, FTIR, 1H NMR, TEM, and SEM techniques were used in the characterization of the products. They had a thermo-responsive character and exhibited volume phase transition at ∼ 36°C. A plasticizer effect of PEG in graft copolymers was also observed, indicating a lower glass transition temperature than that of pure PNIPAM. Homo and copolymerization kinetics were also evaluated. © 2011 Wiley Periodicals, Inc. J Appl Polym Sci, 2012
Stage Transformation of Lithium‐Graphite Intercalation Compounds Caused by Electrochemical Lithium Intercalation

The kinetics of the stage transformation of lithium-graphite intercalation compounds from dilute stage 1 to stage 4 were studied using potential-step chronoamperometry and alternating current impedance spectroscopy. Highly oriented pyrolytic graphite was used as a host material. The current-transient curve showed a current hump, suggesting that the stage transformation was initiated by the nucleation and growth of stage 4. The phase-boundary movement was discussed quantitatively using a simple geometric model. The phase boundary progressed in proportion to time during the initial stage. The rate constant was inversely proportional to the product of the interfacial resistance and the geometric edge-plane area, indicating that the phase-boundary movement was determined by the rate of the reaction at the graphite/electrolyte interface. In the following stage, the phase boundary advanced in proportion to the square root of time. The parabolic rate constant obtained experimentally was in satisfactory agreement with that calculated using Wagner`s classical model which describes the diffusion within two phases separated by a phase boundary. These results indicated that the phase-boundary movement was initially determined by the rate of the interfacial electrochemical reaction and was controlled thereafter by a diffusion process.
Propagation of Sinusoidal Small‐Amplitude Waves in a Deformed Viscoelastic Solid. II

The propagation of a sinusoidal wave of small amplitude in an initially isotropic viscoelastic solid, which is subjected to a static pure homogeneous deformation, is discussed. The secular equation for a plane wave propagating an arbitrary direction with respect to the principal directions of the static deformation is derived. The complex slownesses corresponding to propagation along the principal axes of the static strain are found. Relations are obtained between these and the principal stresses associated with the static deformation, which generalize earlier formulas obtained by Ericksen for elastic materials.
Studies on the Constituents of Panacis Japonici Rhizoma. IV. The Structure of Chikusetsusaponin V

The chemical structure of chikusetsusaponin III, C40H80O17·2H2O, mp 196-197°, [α]19D+1.5°(MeOH), a crystalline saponin isolated from the rhizome of Panax japonicum was established to be 20 (S)-protopanaxadiol-3-[β-D-glucopyranosyl(1→2)]-[β-D-xylopyranosyl(1→6)]-β-D-glucopyranoside as represented by formula (I). It is very remarkable that the rhizome of Panax japonicum which has been used as the substitute drug of "Ginseng"in Japan, contains the homologous saponin of the ginseng.