Miracle-dz/UniFAR-FTUs huggingface dataset:
Neural Correlates Underlying Social-Cue-Induced Value Change

As humans are social beings, human behavior and cognition are fundamentally shaped by information provided by peers, making human subjective value for rewards prone to be manipulated by perceived social information. Even subtle nonverbal social information, such as others' eye gazes, can influence value assignment, such as food value. In this study, we investigate the neural underpinnings of how gaze cues modify participants' food value (both genders) by means of functional magnetic resonance imaging. During the gaze-cuing task, food items were repeatedly presented either while others looked at them or while they were ignored by others. We determined participants' food values by assessing their willingness to pay before and after a standard gaze-cuing training. Results revealed that participants were willing to pay significantly more for food items that were attended to by others compared with the unattended to food items. Neural data showed that differences in subjective values between the two conditions were accompanied by enhanced activity in the inferior frontal gyrus, middle temporal gyrus, and caudate after food items were attended to. Furthermore, the functional connectivity between the caudate and the angular gyrus precisely predicted the individual differences in the preference shift. Our results unveil the key neural mechanism underlying the influence of social cues on the subjective value of food and highlight the crucial role of social context in shaping subjective value for food rewards in human. SIGNIFICANCE STATEMENT We investigated how social information like others' gaze toward foods affects individuals' food value. We found that individuals more often choose food items that were looked at by another person compared with food items that were ignored. Using neuroimaging, we showed that this increased value for attended to food items was associated with higher brain activity in the inferior frontal gyrus, middle temporal gyrus, and caudate. Furthermore, functional connectivity between the caudate and the angular gyrus was associated with individual differences in values for food items that were attended to by others versus being ignored. These findings provide novel insights into how the brain integrates social information into food value and could suggest possible interventions like using gaze cuing to promote healthier food choices.
Etiology, Pathophysiology and Mortality of Shock in Children in Low (Middle) Income Countries: A Systematic Review

Abstract Objectives Shock is a life-threatening condition in children in low- and middle-income countries (LMIC), with several controversies. This systematic review summarizes the etiology, pathophysiology and mortality of shock in children in LMIC. Methods We searched for studies reporting on children with shock in LMIC in PubMed, Embase and through snowballing (up to 1 October 2019). Studies conducted in LMIC that reported on shock in children (1 month–18 years) were included. We excluded studies only containing data on neonates, cardiac surgery patients or iatrogenic causes. We presented prevalence data, pooled mortality estimates and conducted subgroup analyses per definition, region and disease. Etiology and pathophysiology data were systematically collected. Results We identified 959 studies and included 59 studies of which six primarily studied shock. Definitions used for shock were classified into five groups. Prevalence of shock ranged from 1.5% in a pediatric hospital population to 44.3% in critically ill children. Pooled mortality estimates ranged between 3.9-33.3% for the five definition groups. Important etiologies included gastroenteritis, sepsis, malaria and severe anemia, which often coincided. The pathophysiology was poorly studied but suggests that in addition to hypovolemia, dissociative and cardiogenic shock are common in LMIC. Conclusions Shock is associated with high mortality in hospitalized children in LMIC. Despite the importance few studies investigated shock and as a consequence limited data on etiology and pathophysiology of shock is available. A uniform bedside definition may help boost future studies unravelling shock etiology and pathophysiology in LMIC.
Model-based development of a compliant locomotion system for a small scout rover

All currently active planetary exploration robots employ wheels for locomotion. In this work an alternative robotic locomotion concept is examined: the rimless wheel, also known as whegs. It has been proven to be successful in traversing rough terrain on earth and inhibits an appealing simplicity in its mechanics and controls. These aspects along with its inherent redundancy make the rimless wheel particularly suited for planetary exploration. The rimless wheel’s kinematics and compliant spokes are analytically examined using mechanical models. The dynamics of these models are explored in a computational multi-body simulation which confirms the conclusions drawn from the analytical models about running, climbing and movement on rough terrain. A parameter variation then yields a set of suitable parameters for a future scout rover. The application in sand is considered separately both analytically and computationally. Based on these results a single wheel is build and tested on the conclusions drawn from modelling and simulation. These experiments provide strong support that the two-sided goal of efficient movement on hard and flat surfaces as well as reliable negotiation of rough terrain can be achieved with the developed locomotion system.
“Any Reason is Valid:” How an Unexpected Abortion Disclosure is Received by an Online Community

ABSTRACT This study utilized a social media post by a well-known social media influencer and the accompanying 63 responses to explore feelings and experiences related to abortion. This study employed qualitative thematic analysis and identified three themes related to reasons for abortion (i.e., relationship issues, not being ready for pregnancy, and other reasons) and one supplemental theme of bystander support. Findings highlight the efforts of many respondents to normalize abortion as an issue of women’s health and women’s rights. In fact, in response to the original post’s discussion regarding valid reasons for an abortion, most respondents remarked similarly that any reason is valid. While study limitations include concerns regarding generalizability, this study provides access to abortion experiences outside of a traditional health clinic survey and insight into the abortion beliefs of women, both who have and have not experienced an abortion. Findings are in line with previous studies which found that multiple reasons are cited for obtaining an abortion, but also revealed a more supportive climate than the divisive discourse typically portrayed in the media. This suggests the timing may be conducive for efforts aiming to normalize abortion and reduce stigma, including potential avenues for interventions (e.g., social networks and platforms). Lastly, the innovative use of social media to inform this study should be considered by others as they seek to understand and explore topics that can be challenging to study.
Surgeon Thyroidectomy Case Volume Impacts Disease‐free Survival in the Management of Thyroid Cancer

To assess the association between surgeons thyroidectomy case volume and disease‐free survival (DFS) for patients with well‐differentiated thyroid cancer (WDTC). A secondary objective was to assess a surgeon volume cutoff to optimize outcomes in those with WDTC. We hypothesized that surgeon volume will be an important predictor of DFS in patients with WDTC after adjusting for hospital volume and sociodemographic and clinical factors.
Exploring Issues in Agile Requirements Engineering in the South African Software Industry

Issues of the agile requirements engineering (ARE) process are abundant and pervasive throughout software projects. The aim of this study was to determine common issues experienced in agile requirements engineering in the South African software industry and identify tools and frameworks to mitigate risks emanating from such problems. This includes finding out how much value software practitioners put in the agile principles of the Agile Manifesto. This study was essentially quantitative. Self‐administered questionnaires were used to collect required data which was then subjected to exploratory data analysis, a tool for statistical analysis. The results suggest that software practitioners have a strong penchant for principles of the Agile Manifesto. A detailed baseline of issues in agile requirements engineering was created along with a set of recommended tools and techniques used in the software industry. And developers are divergent on the idea of non‐functional requirements integration which is vital for software quality.
Millipede Salvage in South-Western Victoria

Millipedes and other litter invertebrates were sampled in forest patches scattered over approximately 3000 km of southwest Victorian farmland, mainly between the Eumeralla and Hopkins Rivers. Three new, geographically restricted species of Somethus (Polydesmida: Paradoxosomatidae) were collected. Litter fauna in the sampled patches, apart from Framlingham Forest, included few species that are poor dispersers. Absences may be the historical legacy of past habitat fragmentation, subsequent local extinctions and a very low probability of patch recolonisation.
The global mRNA vaccine patent landscape

ABSTRACT In light of their quick development and low risk, mRNA vaccines are gradually replacing traditional vaccines. In order to characterize the patent landscape of mRNA vaccines, this study collated mRNA vaccine–related applications that have been registered since 1962. Accordingly, the 1852 patent families were discussed in relation to their temporal distribution, geographic scope, organizational assignees, and co–patenting activities. mRNA vaccines were shown to demonstrate promise in infectious disease, cancer immunotherapy, and allergic disease, with a focus on lipid nanoparticles. Notably, these vaccines are being developed against a backdrop of fierce industrial competition and intensive collaboration with a rise in applications. The findings of this study highlighted cutting–edge inventions, key players, and collaboration dynamics among institutions. By understanding the landscape of mRNA vaccine patents, researchers and those in industry may better comprehend the latest trends in this area, which may also assist relevant decision–making by academics, government officials, and industrial leaders.
Monochorionic twins with 15q26.3 duplication presenting with selective intrauterine growth restriction and discordant cardiac anomalies: A case report

Duplication of the distal end of chromosome 15q has been previously implicated in a characteristic overgrowth syndrome. Additionally, many patients have other congenital malformations, including cardiac, renal, genital, and musculoskeletal anomalies. However, some patients may present with intrauterine growth restriction and short stature. Different breakpoints within 15q, as well as different environmental factors, may underlie these varied presentations.
Shame Broadcasts Social Norms: The Positive Social Effects of Shame on Norm Acquisition and Normative Behavior

How does shame affect social cohesion? Prior work has drawn divergent conclusions to this question because shame can spur maladaptive behaviors for people who experience it. However, past work has overlooked the interindividual effects of shame—how one’s expression of shame affects people who witness it. We investigated these social-learning effects of shame and identified norm transmission as a reliable route by which shame facilitates social cohesion. Across five studies and two supplemental studies with U.S.-based adult participants (N = 3,726), we manipulated whether someone conveys shame, no specific emotion, or other discrete emotions regarding their behavior. We then assessed the effect of this emotional expression on participants’ norm inferences and norm-conforming behavior. We found that shame broadcasts particularly strong signals about social norms, and people adjust their behavior to align with these norms. We discuss how these findings challenge common conclusions about shame and generate insights about shame’s influence on social life.
Review on 3D printing in dentistry: conventional to personalized dental care

Abstract The CAD (Computer-aided design) and CAM (computer-aided manufacturing) have most applications in the manufacturing of fully automated, personalized dental devices and tailor-made treatment plans. 3D printing is one of the most rapidly expanding and new methods of manufacturing different things because of its on-demand and high productivity within the cost-effective manner which have a variety of applications in healthcare, pharmaceuticals, orthopaedics, engineered tissue models, medical devices, defence industries, automotive and aerospace sectors. Due to its emerging applications in the various sectors, the healthcare, Industries, and academic sectors are attracted towards the 3D printed materials. This review talks about the dental implants, polymers that are employed in concocting dental implants, critical parameters, and challenges which are to be considered while preparing these implants, advantages of 3D printing in the field of dentistry and the current trends. it discusses the variety of applications of 3D printed materials in the field of dentistry. Along with their method of fabrication, their critical process parameters (CPPs) are also discussed.
Experiences of genetic testing among individuals with retinitis pigmentosa

ABSTRACT Background Retinitis pigmentosa (RP) is a genetically heterogeneous retinal dystrophy which results in progressive vision loss. There is scant literature on the experiences of genetic testing in patients with RP. Materials and Methods Patients with a clinical diagnosis of RP who received genetic testing at the Wills Eye Ocular Genetics clinic between 2016 and 2020 were recruited. Telephone interviews were conducted using a semi-structured guide designed to elicit participant experiences with genetic testing. A thematic analysis was performed to describe patterns in participant responses. Results Twelve patients participated. Seven participants identified as female and five as male, with ages ranging from 22 to 70. Ten patients had positive genetic test results, while two had negative genetic testing. Reported motivations for genetic testing included qualification for clinical trials (58% of total participants), determination of etiology or usal gene (50%), reproductive concerns (50%), and prognostic outlook (50%). Most participants (75%) expressed satisfaction about their decision to pursue genetic testing. Participants with both positive and negative genetic testing reported persistent uncertainty regarding their prognosis for visual decline (50%). Genetic confirmation of disease leads to initiation of safety and vision-protecting health behaviors (42%). Conclusion Patients with RP are generally satisfied with their testing experience, despite approaching testing with a wide range of motivations and expectations. Future research can leverage this methodology to identify targets for improvement in pre- and post-test education and counselling.
The occurrence of delirium diagnosis among youth hospitalizations in the United States: A Kids' Inpatient Database analysis

Delirium is an acute neuropsychiatric condition associated with increased morbidity and mortality. There is increasing recognition of delirium as a substantial health burden in younger patients, although few studies have characterized its occurrence. This study analyzes the occurrence of delirium diagnosis, its comorbidities, and cost among youth hospitalized in the United States.
Evaluating the impact of eligibility criteria in first-line clinical trials for follicular lymphoma: a MER/LEO cohort analysis

Abstract Cancer clinical trial eligibility criteria may create patient populations studied in trials that do not reflect the patient populations treated in the real-world setting. Follicular lymphoma (FL) is an indolent lymphoma with heterogeneous presentations across a broad range of individuals, resulting in many acceptable management strategies. We evaluated how first-line clinical trial eligibility criteria impacted the demographic makeup and outcomes of patients with FL for whom systemic therapy might be considered. We compared the characteristics of 196 patients with FL from a single institution to eligibility criteria from 10 first-line FL trials on clinicaltrials.gov. Next, we tabulated eligibility criteria from 24 first-line FL protocols and evaluated their impact on 1198 patients with FL with stages II to IV disease from the prospective Molecular Epidemiology Resource (MER) and Lymphoma Epidemiology of Outcomes (LEO) cohort studies. We found that 39.8% and 52.7% of patients with FL might be excluded from clinical trials based on eligibility criteria derived from clinicaltrials.gov and protocol documents, respectively. Patients excluded because of renal function, prior malignancy, and self-reported serious health conditions tended to be older. Expanding stage requirement from III-IV to II-IV, and platelet requirement from ≥150 000 to ≥75 000 increased population size by 21% and 8%, respectively, in MER and by 16% and 13%, respectively, in LEO, without impacting patient demographics or outcomes. These data suggest that management of older individuals with FL may not be fully informed by recent clinical trials. Moreover, liberalizing stage and platelet criteria might expand the eligible population and allow for quicker trial accrual without impacting outcomes.
A Collaborative Learning Tracking Network for Remote Sensing Videos

With the increasing accessibility of remote sensing videos, remote sensing tracking is gradually becoming a hot issue. However, accurately detecting and tracking in complex remote sensing scenes is still a challenge. In this article, we propose a collaborative learning tracking network for remote sensing videos, including a consistent receptive field parallel fusion module (CRFPF), dual-branch spatial-channel co-attention (DSCA) module, and geometric constraint retrack strategy (GCRT). Considering the small-size objects of remote sensing scenes are difficult for general forward networks to extract effective features, we propose a CRFPF-module to establish parallel branches with consistent receptive fields to separately extract from shallow to deep features and then fuse hierarchical features adaptively. Since the objects and their background are difficult to distinguish, the proposed DSCA-module uses the spatial-channel co-attention mechanism to collaboratively learn the relevant information, which enhances the saliency of the objects and regresses to precise bounding boxes. Considering the interference of similar objects, we designed a GCRT-strategy to judge whether there is a false detection through the estimated motion trajectory and then recover the correct object by weakening the feature response of interference. The experimental results and theoretical analysis on multiple datasets demonstrate our proposed method’s feasibility and effectiveness. Code and net are available at https://github.com/Dawn5786/CoCRF-TrackNet.
Genetic Variation and Population Structure of the Old World Bollworm Helicoverpa armigera (Hübner, 1808) (Lepidoptera: Noctuidae) in Ethiopia

Abstract Helicoverpa armigera is one of the most destructive insect pests of economically valuable crops in the world. Despite its economic importance, the population genetic structure of this insect remains unexplored in Ethiopia. To investigate the genetic diversity and population structure of H. armigera, we sampled 170 individuals from 15 populations throughout Ethiopia. We sequenced a fragment of the mitochondrial cytochrome b (cyt b) gene and five exon-primed intron-crossing (EPIC) markers. Twenty cyt b haplotypes with low-to-moderate haplotype diversity (mean Hd = 0.537) and high nucleotide diversity (mean Pi = 0.00339) were identified. The most frequently observed and widely distributed cyt b haplotype was designated as Hap_1 (67.058%), which is identical to sequences found across the globe. Tajima's D and Fu's F for the cyt b data were negative, supporting a model of population expansion. Within populations, a mean of 2.493 alleles/locus was recorded across the five EPIC loci, ranging from 1.200 to 3.600 alleles/locus. The highest mean effective number of alleles/population was 2.369 and the lowest was 1.178. The mean observed heterozygosity (HO) of the five loci (0–0.289; mean 0.104 ± 0.020) was lower than the expected heterozygosity (HE) (0.095–0.523; mean 0.258 ± 0.028). AMOVA detected significant genetic structure with 61% of the total molecular genetic variation of EPIC genotypes occurring between populations, suggesting a considerable degree of differentiation among populations. STRUCTURE analyses clustered the H. armigera populations into three distinct population groups but very low isolation by distance (R 2 = 0.0132, P < 0.05).
Characteristics of antioxidant substances and identification of antioxidant peptides in duck embryo eggs

ABSTRACT 1. Oxidative stress in duck embryos undergoes dynamic change during incubation. However, the detailed change characteristics has not been studied yet. Here, we explored the dynamic change characteristics of different antioxidant substances in duck embryo eggs during incubation. 2. The following trial assayed antioxidant substances, including vitamins E (VE) and C (VC), glutathione (GSH), reduced glutathione (reduced GSH), oxidative glutathione (GSSG), superoxide dismutase (SOD), catalase (CAT), glutathione peroxidase (GSH-px), and malonic dialdehyde (MDA). Five antioxidant peptides (DY1, DY2, DY3, DY4 and DY5) were screened and their protective effect on HepG2 cells and their mechanism of action determined. 3. The results showed that antioxidant substances underwent a dynamic change during incubation through various mechanisms. Moreover, the T-AOC of duck embryos at different incubation times, firstly increased and then decreased, reaching the highest level on d 15 during incubation. The peptide DY2 (TVDGPSGKLWRD) exhibited high antioxidant activity in vitro, and is known to regulate the apoptosis pathway in mitochondria. 4. The data indicated that duck embryos can be used for the development of related antioxidant products and purification of new bioactive peptides.