Miracle-dz/UniFAR-FTUs huggingface dataset:
INSTRUCTIONAL DESIGN AND ASSESSMENT An Elective Course in Adult Acute Care Medicine Using a Hybrid Delivery System

Objective. To develop and assess the effectiveness of an elective course modeled after activities students encounter on internal medicine advanced pharmacy practice experiences (APPEs). Design. This hybrid elective course used a Web-based course management system linking pre-class lectures and assignments, classroom discussions, and projects to promote active student learning. Assessment. Assessment of student performance was based on assignments, quizzes, and participation in classroom discussions. Students were surveyed to ascertain their opinion of the elective. Conclusion. This elective in adult acute care medicine increased student exposure to inpatient settings and provided students additional opportunities to communicate effectively, evaluate medical literature, and think critically.
The visual servoing system "CYCLOPE" designed for dynamic stabilisation of AUV and ROV

The paper presents the CYCLOPE control system designed and developed by Ifremer for the dynamic stabilisation of unmanned underwater vehicles (UUVs), thanks to visual servoing. The CYCLOPE system has been designed because optical stabilisation is the more suitable solution for controlling both UUV motion and stability when performing small motions. The CYCLOPE system is a complete hardware and software system designed to be installed on-board an AUV or to be connected to an ROV surface control station, in order to perform autonomous station-keeping task. The CYCLOPE system software is based on the OPTIC/spl I.bar/DP Software/sup /spl reg// developed by Ifremer; it is used to perform the video image processing and the control computation. Prior to control computation, CYCLOPE fuses the calculated and measured visual information with the navigation data provided by the various sensors fitting the underwater vehicle.
Ground beetles (Coleoptera Carabidae) diversity patterns in forest habitats of high conservation value, Southern Bulgaria

The study presents a comparison between the diversity of the carabid beetles taxocoenoses and their spatial distribution in different forest types of high conservation value in Strandzha (8 sites), the Rhodopes (4 sites) and Belasitsa (6 sites) mountains. The diversity indices have demonstrated the highest species richness and the highest diversity values in the riverside sites of Strandzha Mountain. The lowest species richness has been found in the tertiary relict forest of oriental beech with undergrowth of rhododendron (Strandzha Mountain) and in the centuryold sweet chestnut forest (Belasitsa Mountain). The lowest values of diversity and evenness have been found in the beech forest sites in Strandzha and the Rhodopes due to the prevalence of the Aptinus species. This low diversity is a natural condition for the studied sites. The classification of the ground beetles complexes from the studied sites by similarity indices and TWINSPAN has been made. A high level of dissimilarity among the sites has been found, showing unique species composition and abundance models in each site. Carabid beetles taxocoenoses in the forests of Strandzha Mountain have shown a low similarity level by species composition and abundance even in the range of the same mountain. Indicator species have been shown. The ordination of the carabid complexes has showed that the sites have been distributed continuously along two significant gradients. The first gradient has been found to be the altitude (probably due to the temperature conditions) in a combination with the hydrological regime. The second significant gradient probably has been under the complex influence of the climate conditions and vegetation type. Carabidae; diversity; conservation; Bulgaria.
Process of Building Reference Ontology for Higher Education

Most ontologies are application ontologies, that are not reusable and are difficult to link together as they are too specific. Reference ontology is able to contribute significantly in reducing the issue of ontology applications specificity. Particularly considering higher education domain, we think that a reference ontology dedicated to this knowledge area, can be regarded as a valuable tool for several stakeholders interested in analyzing the system of higher education as a whole, especially in a context of academic systems diversity all over the world. Motivated by this potential application and even more, we decided to build a reference ontology called HERO ontology, which stands for "Higher Education Reference Ontology". In this paper we explain HERO ontology building process from requirements specification until ontology evaluation using NeOn methodology.
Will a Parser Overtake Achilles? First experiments on parsing the Ancient Greek Dependency Treebank

We present a number of experiments on parsing the Ancient Greek Dependency Treebank (AGDT), i.e. the largest syntactically annotated corpus of Ancient Greek currently available (350k words ca). Although the AGDT is rather unbalanced and far from being representative of all genres and periods of Ancient Greek, no attempt has been made so far to perform automatic dependency parsing of Ancient Greek texts. By testing and evaluating one probabilistic dependency parser (MaltParser), we focus on how to improve the parsing accuracy and how to customize a feature model that fits the distinctive properties of Ancient Greek syntax. Also, we prove the impact of genre and author diversity on parsing performances.
A high‐performance distributed file system for large‐scale concurrent HD video streams

With the rapid development of intelligent transportation technology, high‐definition data storage, and processing of massive amounts of video surveillance have become key issues. When thousands of high‐bit‐rate video streaming concurrently writes, disk I/O throughput becomes a bottleneck. In addition, this leads to serious energy consumption and disk abrasion. To solve these problems, a new distributed file system for high concurrent and high‐bit‐rate writing is designed. It combines an optimized data storage model, efficient metadata management, and exquisite disk schedule mechanism. The optimized data storage model uses a file pre‐allocation strategy and multiple‐stream input modulating technology to convert the randomly concurrent writes on the disk into sequential writes; the metadata management provides an efficient means of retrieving the specified data; and the dual‐partition schedule mechanism can ensure the disk stability with less abrasion. Through this distributed file system, the disk I/O throughput can be saturated in a high concurrent writing environment. The performance evaluation results demonstrate that the I/O throughput of a normal 7200RPM SATA III disk in our scheme can be stabilized at 150MB/s, easily to support 300 concurrent high‐definition video streams (4Mbit/s each). The distributed file system with eight commodity servers can afford the ability of supporting 8000 high‐definition video streams concurrently writing, which is far greater than the existing video surveillance storage solutions. Copyright © 2015 John Wiley & Sons, Ltd.
Effects of Gestational Exposure to Chlorpyrifos on Postnatal Central and Peripheral Cholinergic Neurochemistry

The effects of gestational exposure to the commonly used organophosphorus insecticide chlorpyrifos (O,O-diethyl O-[3,5,6-trichloro-2-pyridinyl]phosphorothioate) on postnatal central and peripheral cholinergic neurochemistry were investigated. Pregnant rats were orally dosed daily with chlorpyrifos (0, 3, 5, or 7 mg/kg) in corn oil from gestation day 6 to 20. Pups were sacrificed on postnatal days 1, 3, 6, 9, and 12 for the determination of brain, heart, lung, and serum cholinesterase, and brain choline acetyltransferase activities, along with liver carboxylesterase activity. Exposure to chlorpyrifos did not produce signs of overt toxicity to the dams or developing offspring. Cholinesterase activities were inhibited in a dose-related manner, with brain cholin-esterase inhibition of about 26%, 32%, and 45% on postnatal day 1. Inhibition of brain cholineste-rase persisted in all treatment groups until postnatal day 6 and in the medium and high-dosage groups through postnatal day 9. Liver carboxylesterase activity was also inhibited in a dose-related manner, with a recovery profile parallel to that of brain cholinesterase. Choline acetyltransferase activity was decreased by about 13% in the high-dosage group on postnatal days 9 and 12. These results indicate that gestational exposure to chlorpyrifos results in relatively persistent inhibition of brain cholinesterase and a delayed depression of choline acetyltransferase at a time when brain cholinesterase activity had returned to control levels in the high-dosage group.
A method for real-time peer-to-peer traffic classification based on C4.5

Classification results of network traffic using machine learning rely on attribute information captured at the end of a flow. In contrast, real network requires classifying traffic before a flow has finished. This implies that classification must be achieved using information extracted from the most recent N packets at any arbitrary point in a flow's lifetime. In order to classify peer-to-peer (P2P) applications as early as possible, different P2P applications' characteristics are studied and an attribute set, being able to effectively and promptly distinguish different P2P applications, is proposed. The simulative results using C4.5 decision tree algorithm and sliding window method show that, compared to current attribute sets, this set is more effective in classification, with accuracy achieving 96.7%. Besides, it proves that accuracy using this set keeps stable, though a number of initial packets in a flow are lost.
Impact of spruce forest on rainfall interception and seasonal snow cover evolution in the Western Tatra Mountains, Slovakia

The paper analyzes the impacts of the spruce forest on precipitation interception and evolution of snow cover in the mountain catchment of the Jalovecký creek, the Western Tatra Mountains, Slovakia. Both processes were monitored at the elevation of 1420 m a.s. l. Interception was measured from the end of August 2006 until November 2008 by a network of 13 raingauges. Mean interception over the studied period in forest window was 23%. Mean values for the dripping zone under tree branches, near stems of the trees and under the young trees were 28%, 65% and 44%, respectively. With exception of forest window, the interception at the same characteristic positions was highly variable. Calculated daily precipitation thresholds needed to fulfill the storage capacity of the canopy were about 0.8–0.9 mm.Differences in snow accumulation and melt in the open area (elevation 1500 m a.s.l.) and in the forest were measured in winters 2003–2008. Snow depths (SD) and water equivalents (SWE) were typically smaller in the forest, although the differences were getting smaller towards the end of snow season. SD and SWE in the forest were higher than in the open area for a short time before the end of season in winters 2003 and 2005. The correlations between SD and SWE in the open area and in the forest explained about 90% of variability. The energy balance snow model UEB satisfactorily simulated the evolution of snow cover in the forest and in the open area.
Assessing modern health worries: Dimensionality and factorial invariance across age and sex of the Modern Health Worries Scale in a general population sample

Previous work suggests a four-factor structure of the Modern Health Worries Scale. This study is the first to investigate its dimensionality and factorial invariance across age and sex in a representative population sample (N = 2524) using confirmatory factor analysis. The proposed four-factor model failed to achieve good model fit. Model fit was optimized by allowing correlating error terms resulting in acceptable model fit. Multi-group analysis revealed invariance across age and sex. Our study proved the proposed four-factor structure across age and sex. Consequently, the Modern Health Worries Scale can be applied in general population surveys using subscale scores.
HIGH MOISTURE SORGHUM GRAIN SILAGE : EFFECTS OF TANNIN CONTENT AND UREA TREATMENT ON THE PERFORMANCE OF DAIRY COWS

Grain sorghum silage tannin content effect was evaluated on milk production and chemical composition of Argentinean Holstein bred cows, and it are described dry matter (DM) and crude protein (CP) in situ digestion parameters and effective degradability. The base diet was constituted by alfalfa pasture, maize silage, and a protein – mineral supplement, differing in three treatments based on high moisture grain silage characteristic: LTS= Low tannin grain sorghum, HTS= High tannin grain sorghum, and HTSu= High tannin sorghum plus the addition of urea. Grain sorghum silage tannin content affects milk production, without significant alteration of chemical composition. Beside the effect of urea addition on grain sorghum tannin content, improvement in animal response was only moderate.
Actitudes ante la diversidad sexual de la población adolescente de Coslada (Madrid) y San Bartolomé de Tirajana (Gran Canaria)

La investigacion, hecha sobre una muestra de mas de 4.500 adolescentes, se ha realizado paralelamente en dos municipios tan diferentes como son Coslada (Madrid) y San Bartolome de Tirajana (Gran Canaria). En este ultimo se encuentra el famoso destino de turismo gay Maspalomas. La investigacion partio de un encargo de la Concejalia de Mujer e Igualdad del Ayuntamiento de Coslada al Area de Educacion de la FELGTB (COGAM es fundador y socio de la FELGTB). Posteriormente se incorporo el Ayuntamiento de San Bartolome. Los resultados que se dan a conocer hoy jueves vuelven a poner de manifiesto la urgente necesidad de trabajar la diversidad afectivo-sexual en ambito escolar, tanto por la gran ignorancia que la mayoria de los jovenes tienen sobre el tema como por la situacion de riesgo que padecen los alumnos LGTB. Por primera vez en una investigacion de este tipo se incide sobre la identidad sexual de los entrevistados, sobre su origen cultural y religioso, asi como sobre la actitud de sus familias. Esta investigacion la han llevado a cabo un equipo de antropologos dirigido por Jose Ignacio Pichardo y Belen Molinuevo en Madrid y por Pedro Rodriguez en Gran Canaria. Han contado con el apoyo de los/las voluntarios/as tanto de la Comision de Educacion de COGAM como de GAMA.
Gold Mining and Mercury Bioaccumulation in a Floodplain Lake and Main Channel of the Tambopata River, Perú

Contamination of water bodies by inorganic mercury (Hg[II]) used in placer mining of gold deposits in the Madre de Dios Department, Peru, contributes to the bioaccumulation of methylmercury (MeHg) in fish tissue. We measured MeHg and total Hg (THg) concentrations (mg/kg wet weight [ww] tissue) of thirteen fish species from the Tambopata River, Peru, and the connected oxbow lake Tres Chimbadas. We also used stable isotope analysis (δ 15 N and δ 13 C) to estimate trophic positions of fishes. Average MeHg concentrations of fish species ranged from 0.042 mg/kg ww (Satanoperca jurupari) to 0.463 mg/kg ww (Hoplias malabaricus) in the main channel and from 0.090 mg/kg ww (Parauchenipterus sp.) to 1.282 mg/kg ww (Pimelodina flavipinnis) in the lake. Spearman rank correlation indicated that trophic position had no influence on MeHg concentrations of species in the main channel, but in the lake, trophic positions of species were positively associated with MeHg. Migrations of the pimelodid catfish surveyed from the main channel are well documented. Because little gold mining occurs at our study site, fishes from the main channel may be bioaccumulating MeHg from areas where mining is widespread. Fish species that reside in the lake are relatively sedentary and migration is limited by the brief period of floodplain inundation and the long, narrow corridor that connects the lake to the main channel; lake sediments are therefore the likely source for MeHg bioaccumulation. Five out of the eight fish species surveyed from the main channel and two out of the five species from the lake had MeHg levels higher than United States Environmental Protection Agency fish tissue criterion for human consumption.
Detection of Alginate Oligosaccharides from Mollusks

We attempted in this study to detect alginate oligosaccharides (AO) from mollusks. The samples used were digestive organs taken from turban shells and abalones which commonly ate brown algae. High-performance liquid chromatography (HPLC) and negative-ion electrospray ionization (ESI) quadrupole time-of-flight (Q-TOF) mass spectrometry (MS) analyses were used to confirm the presence of AO. Samples spiked with AO resulted in observable peaks where the HPLC area was increased. The highest content was estimated to be 401.8 mg/100 g of digestive organ. The product-ion data derived from AO molecular weight were detected at a constant interval by Q-TOF MS/MS analysis. These findings indicate that AO was present in the digestive organs of mollusks.
A framework for Twitter events detection, differentiation and its application for retail brands

We propose a framework for Twitter events detection, differentiation and quantification of their significance for predicting spikes in sales. In previous approaches, the differentiation between Twitter events has mainly been done based on spatial, temporal or topic information. We suggest a novel approach that performs clustering of Twitter events based on their shapes (taking into account growth and relaxation signatures). Our study provides empirical evidence that through events differentiation based on their shape one can clearly identify clusters of Twitter events that contain more information about future sales than the non-clustered Twitter signal. We also propose a method for automatic identification of the optimum event window, solving a task of window selection, which is a common problem in the event study field. The framework described in this paper was tested on a large-scale dataset of 150 million Tweets and sales data of 75 brands, and can be applied to the analysis of time series from other domains.
Immune Complexes in Human Melanoma: A Consequence of Deranged Immune Regulation

Circulating immune complexes were detected in 62 individuals with malignant melanoma by precipitation with isolated human C1q and polyclonal rheumatoid factors. In 56 patients the C1q deviation assay showed low to moderate levels of complexes, with increased amounts with advancing stage of disease. Both heavy (>19S) and intermediate (7S to 19S) varieties were present, and complexes containing tumor antigen‐antibody or antibody‐ anti‐antibody were identified. Complexes were found in the kidneys of one patient with malignancy and the nephrotic syndrome and in two further patients with melanoma in whom there were DO clinical manifestations of nephrosis. Serial determinations in 51 patients showed slow cyclic variations in the levels of complexes and fluctuations in response to therapy. The coexistence of anti‐antibodies, immune complex disease, and anergy in melanoma patients may indicate a deranged immune regulation consequent to chronic antigenic stimulation by the tumor.
Primary Coronary Microvascular Dysfunction: Clinical Presentation, Pathophysiology, and Management

Myocardial ischemia is usually caused by abnormalities of epicardial coronary arteries. In the past 30 years, however, several studies have shown that abnormalities in coronary microcirculation may also cause or contribute to myocardial ischemia in several conditions. Accordingly, Camici and Crea1 have recently proposed a classification of coronary microvascular dysfunction (CMVD) based on the clinical setting in which it occurs (eg, obstructive coronary artery disease [CAD], cardiomyopathy, and systemic diseases) (Table 1). In these various conditions, CMVD can be caused by specific mechanisms related to the underlying disease. View this table: Table 1. Classification of CMVD According to its Pathogenetic Mechanisms (Derived From Camici and Crea 1 ) In a number of patients who present with angina attacks in the absence of any apparent cardiac or systemic disease, CMVD has been suggested to be the unique cause of symptoms. This condition is known as microvascular angina (MVA)2 and can be better defined as primary MVA to distinguish it from MVA occurring in the setting of specific diseases, which can be defined as secondary MVA. In clinical practice, primary MVA is usually suspected, by exclusion, in patients with sufficiently typical chest pain in whom, despite abnormalities of the ECG and/or stress test results indicative of myocardial ischemia, arteriography surprisingly fails to show fixed or dynamic obstructions in epicardial coronary arteries.3 Primary MVA, however, includes heterogeneous groups of patients, with different pathogenetic and pathophysiological mechanisms of CMVD, who might have different clinical implications and need different diagnostic and therapeutic approaches. In several previous studies, however, patients with different characteristics of chest pain, possibly related to different mechanisms of CMVD or even to nonischemic or noncardiac causes, have often been considered together, usually under the general descriptive term of chest pain with normal coronary arteries, which may have contributed to generate contrasting results …
Release of Shiga Toxin from Shigella dysenteriae 1 by Polymyxin B

Release of Shiga toxin from Shigella dysenteriae 1 was found to occur after exposure to polymyxin B. The amount of toxin released was dependent on both the polymyxin concentration and time of incubation. An immunoblot characterization of the Shiga toxin released by polymyxin treatment demonstrated that it is electrophoretically similar to purified Shiga toxin and to Shiga toxin present in crude bacterial sonicates of S. dysenteriae 1 cells.
Mortalin, Apoptosis, and Neurodegeneration

Mortalin is a highly conserved heat-shock chaperone usually found in multiple subcellular locations. It has several binding partners and has been implicated in various functions ranging from stress response, control of cell proliferation, and inhibition/prevention of apoptosis. The activity of this protein involves different structural and functional mechanisms, and minor alterations in its expression level may lead to serious biological consequences, including neurodegeneration. In this article we review the most current data associated with mortalin’s binding partners and how these protein-protein interactions may be implicated in apoptosis and neurodegeneration. A complete understanding of the molecular pathways in which mortalin is involved is important for the development of therapeutic strategies for cancer and neurodegenerative diseases.