Miracle-dz/UniFAR-FTUs huggingface dataset:
Open Marketing: Conceptualizing external parties' strategic marketing activities

(iv) marketing). The paper focuses empirically on the open marketing idea discussing the concept of roles in marketing. Open marketing as conceptualized in this paper refers to how external parties take part in strategic, integrative marketing activities. To distinguish this more recent trend in marketing from traditional meanings of marketing, the paper provides a typology on roles and role keepers in marketing. Four types of roles and role keepers are outlined: 1) marketing as solely being performed by actors in the supplier company communicating offerings, 2) an activity shared among functions of the supplier company, 3) external parties communicating offerings, and 4) external parties contributing to strategic marketing. Using the concept of ‘roles’ in marketing helps to structure activities and actors - or roles and role keepers - and provides a basis for understanding that marketing results from what is done, not merely from who performs it. The paper underlines how new ways of conducting business also have implications for a company’s marketing beyond its borders.
Empathy and Design. A new perspective

Abstract In this contribution we discuss the value of empathic experience as a result to achieve through design driven solutions. Following a phenomenological framework, we draw attention on empathy as an intersubjective experience human relationships are grounded in. Accordingly, we argue that design approach should address the issue of how to create the conditions for the empathic experience, for it is “the very means by which we create social life and advance civilization” (Rifkin, 2010, Chapter 1, Section 2)). From this perspective we reconsider the role of empathy as it is acknowledged in design, shifting it from being a tool for designing more ‘marketable’ and human centred products and/or services, to a pursued effect for products and/or services concerned with relational issues. To achieve this shift we will review the literature about empathy and design, on the one hand, and the application of the Relational Aesthetics theory to design, on the other.
Fault Diagnosis of Wind Turbine Based on Convolution Neural Network Algorithm

Relying on expert diagnosis, it solves the problem of fan failure efficiency and meets the needs of automatic inspection and intelligent operation monitoring of fans. In order to make up for the deficiency of intelligent diagnosis of bearing fault based on vibration signal detection, signal transformation, and convolution neural network identification and improve the ability of intelligent diagnosis, this study designs a deep convolution neural network model and diagnosis algorithm with three pairs of convolution pooling layers and two full connection layers. The experimental verification of the proposed method is carried out based on the public data set, and the effects of three different signal transformation methods based on vibration signal through vibration gray map, short-time Fourier transform time-frequency map, and continuous wavelet transform time-frequency map on the accuracy of diagnosis model are compared and analyzed. A very accurate guarantee is received, close to 100%. The final experimental results demonstrate the effectiveness of the information on the accuracy of diagnostic testing and provide new ideas for the verification and testing of wind turbine wind energy. Compared with other machine learning algorithms, the real-time recognition of machine learning based on time-domain statistical features is lower than that of convolutional neural network methods. The effect of the scale of the trained model on the accuracy of the algorithm is discussed. A sample ratio of 50% and 70% was found to be appropriate.
Endoscopic Resection of Nasal Mucosal Melanoma Using Temporary Transseptal Access

Nasal mucosal melanoma (NMM) is a rare tumor with a poor prognosis. Although an endoscopic resection of malignant nasal tumor now becomes a treatment of choice when the surgical margin can be secured, it is still controversial. We report three cases of NMM that was successfully removed en bloc with clear margins by endoscopic surgery with temporal transseptal access. Cases of a 78-year-old woman, an 83-year-old man, and an 81-year-old man with NMM arising from the inferior turbinate who underwent endoscopic resection of the tumor are discussed in detail. We made temporal transseptal access using septal mucosal flaps. We moved the nasal cavity-occupying tumor to the contralateral side to create a working space to perform endoscopic en bloc resections. This technique is simple yet effective and less invasive than open craniofacial resections for removing malignancies arising from the inferior turbinate.
Mice Immune Responses in 4-1BB

The 4-1BB (a TNFR superfamily member) is an inducible costimulatory molecule that can exert regulatory effects on T cells independently of CD28 stimulation. The in vitro expression of 4-1BB (CD137) is induced following activation of T cells with various stimuli, including anti-TCR mAbs, lectins, and a combination of PMA and ionomycin. To delineate further the physio-logical role of 4-1BB in immunity, mice deﬁcient in this receptor were generated. These mutant mice developed normally, and were viable and fertile. Humoral responses to vesicular stomatitis virus were comparable with those seen in wild-type mice, whereas the IgG2a and IgG3 isotype responses to keyhole limpet hemocyanin were somewhat reduced in the mutant mice. The 4-1BB-deﬁcient mice demonstrated enhanced T cell proliferation in response to mitogens or anti-CD3 even in the environment of reduced ability to secrete growth-supporting cytokines (IL-2 and IL-4). Although T cells from 4-1BB-deﬁcient mice showed enhanced proliferation, the T cell immune responses of these animals, such as cytokine production and CTL activity, were diminished. In addition, 4-1BB deletion appears to play a role in the regulation of myeloid progenitor cell growth, leading to an increase in these precursor cells in peripheral blood, bone marrow, and spleen. The Journal of Immunology, 2002, 168: 5483–5490. two optimum activation: gene. ES cell line E13TG2a was transfected with the linearized plasmid DNA and selected for G418 and ganciclovir resistance, as previously described (18). Genomic DNA from individual selected clones was digested with Sac I and hybridized with a 1.2-kb Sac I/ Xba I fragment external to the targeting vector to screen for homologous recombination, as previously described (19). A DNA restric- tion fragment of 5.5 kb corresponded to the wild-type allele, whereas a new 6.7-kb fragment resulted from the targeted allele. Four targeted clones were obtained from the 50 G418 and ganciclovir-resistant ES cell colonies. The targeted ES cells were microinjected into 3- to 5-day-old C57BL/6 blas- tocysts and transferred to the uterine horn of pseudopregnant C57BL/6 mice. Eight male and seven female chimeras were obtained. We tested for transmission of the mutated allele by mating the chimeras with (C57BL/ 6 (cid:6) DBA/2)F 1 mice. Two males and one female showed germline trans- mission of the targeted allele. Homozygous 4-1BB-deﬁcient mice (4-1BB (cid:4) / ) were bred with C57BL/6 or BALB/c mice for at least seven generations to obtain 4-1BB (cid:4) / (cid:4) mice on the C57BL/6 or BALB/c background. The genotypes of the offspring were determined by Southern blot analysis of DNA obtained from tail biopsies.
Automated Layer Identification and Classification Of Network Packets

— This paper presents a traffic classification scheme to improve classification performance and also the performance of the system. In the proposed scheme we are grouping the correlated flows and classifying it by using a classifier combination framework and aggregating naive Bayes (NB) predictions of the correlated flows. To improve the performance of the system we are detecting the denial-of-service (DOS) packets. We are also classifying the packets according to their size and identifying the applications running on the computers connected to the network to improve the performance of classification. The experimental result shows that packets are classified and layers are identified. We require very less amount of training data for the classification.
Algebraic Constructs for Querying Provenance

— Provenance that records the derivation history of data is useful for a wide variety of applications, including those where an audit trail needs to be provided, where the trust-level attributed to the sources contribute to determining the trust-level in results etc. There have been different efforts for representing provenance information, the most notable being the Open Provenance Model (OPM). OPM defines structures for representing the provenance information as a graph with nodes and edges, and also specifies inference queries that can be expressed in Datalog/SQL. However, the requirements of a query language for provenance information go much beyond those that can be expressed using only inference queries. In our work, we build on OPM and propose two classes of algebraic constructs for querying provenance information: content-based operators that operate on the content of nodes and edges, and structure-based operators that operate on the graph structure of the provenance graph. An user can express a query as a workflow by composing these content-based and structure-based operators. Our operators are powerful, and an user can express a wide variety of interesting queries on the provenance data, that go much beyond simple inference queries as expressible using Datalog/SQL. As part of our evaluation, we show different queries and how they can be expressed using our constructs.
SAR Image Enhancement Based on Phase-Extension Inverse Filtering

In this paper we present a new post enhancement method for single look complex (SLC) SAR imagery, which is based on phase-extension inverse filtering. To obtain a highquality SAR image, the proposed method improves the mainlobe resolution as well as efficiently suppresses the sidelobes with low computational complexity. The proposed method extends the effective signal band up to the maximum-bandwidth allowed by a SAR system. The band-extension is achieved by adjusting the magnitude level of matched filtered SAR spectrum. Because the proposed method preserves the phase components of the spectrum unlike other super-resolution techniques and deconvolution techniques, it enhances a SAR image without causing any displacement. To verify the efficacy of the proposed method we apply it to a simulated SAR image and a real ERS-1 SAR image. The result images show that the proposed method improves the mainlobe resolution with low sidelobe levels. key words: SAR image, high-resolution, deconvolution, enhancement, ERS-1.
Occurrence of Novel Groups of the Domain Bacteria as Revealed by Analysis of Genetic Material Isolated from an Australian Terrestrial Environment

A molecular ecological study was performed on an Australian soil sample to unravel a substantial portion of the bacterial diversity. A large fragment of the 16S rRNA gene was amplified, using DNA isolated by lysing the microorganisms directly within the soil matrix, and a clone library was generated. Comparative sequence analysis of 30 clones and dot blot hybridization of 83 additional clones with defined oligonucleotide probes revealed the presence of three major groups of prokaryotes of the domain Bacteria. The first one comprises 57 clones that indicate relatives of nitrogen-fixing bacteria of the a-2 subclass of the class Proteobacteria; the second group of 7 clones originates from members of the order Planctomycetakes that, however, reveal no close relationship to any of the described Planctomycetaks species; 22 clones of the third group are indicative of members of a novel main line of descent, sharing a common ancestry with members of planctomycetes and chlamydiae.
CORE Scholar CORE Scholar

Current and future research that embodies a pathway to achieving machine common sense (MCS), including Capsule Neural Networks, Hebbian Plasticity Theory, Dual Process Theory, and machine awareness (MA). The final frontier may well involve a framework that is capable of machine curiosity, exploration, automatic self-direction and adaptation. The artificial intelligence (AI) system of the future will possess an innate curiosity and explore its own environment to gain knowledge, exhibiting a basic element of human cognition and awareness. The resulting MA system will possess inherent self-driven curiosity and related entropy in the decision space as it explores the environment in much the same manner as humans do.
Experimental Pharmacology WOLBACHIA ASSOCIATION AND ITS PHYLOGENETIC AFFILIATION OF BRUGIA MALAYI PARASITES FROM INDIA

Wolbachia have established a mutualistic association with filarial nematodes and has a phenomenal implication in its normal development, reproduction and survival. Elimination of Wolbachia by tetracycline class of antibiotic compounds have been suggested and successfully implemented for the treatment of lymphatic filarial parasites. Thereby, is necessary to assess the prevalence of the Wolbachia in B. malayi before such new strategies are employed, across the world. In the present communication, the presence of Wolbachia and phylogenetic affiliation in B. malayi collected from Sevagram, Maharashtra, India, has been addressed.
Firms’ Profitability and Financial Reporting Quality: Pre and Post IFRS Adoption in Nigeria

: - The study examines firms’ profitability and the quality of financial reports: pre and post IFRS adoption in Nigeria. The main objective is to examine the effect of profitability on earnings quality of firms in addition to the impact IFRS has on the profitability of firms in Nigeria. The study uses the quantitative method of analysis, the multiple regression analysis to examine what effect ROE and ROA have on earnings quality and t-test of mean difference to test for difference between the mean of pre and post IFRS adoption. To analyse earnings quality, discretionary accrual is measured using the Jones’ model. The results show that the effect of profitability on the quality of earnings after adoption of IFRS is mix depending on what measure of profitability was adopted. ROE has negative (positive) effect while ROA has positive (negative) effect on discretionary accruals (earnings quality). On the impact of IFRS adoption on profitability of firms, the results show a non-significant impact on the return on equity of firms and a statistically significant impact on the return on assets of firms. Overall, IFRS adoption has had a negative impact on the profitability of firms quoted on the floor of the Nigerian stock exchange.
THE ROLE OF GIVING EAT REMINDER APPLICATION MEDIA TO CHANGES IN KNOWLEDGE, ATTITUDE, BEHAVIOR AND EAT PATTERN OF ADOLESCENT AGE 13-15 YEARS OLD

Background: Adolescence is a period of transition physical, mental, and emotional changes. Adoles- cents usually experience lifestyle changes and eating habits such as excessive dieting, skipping meals, using supplements and adopting diets. Method : The study used the quasy experimental method with pre-test and post-test in the intervention and control groups. The number of samples used in this study amounted to 84 samples Result: Most of the respondents were male (61.9%) with an average age of 14 years. Based on the analysis carried out showed that there were no significant changes in the knowledge, attitudes, behaviors and eating patterns of adolescents before and after the intervention (p> 0.05), but there was a change in diet, the mean score on knowledge and behavior scores increased Conclusion : Nutrition education with the application of Remind me application can increase the knowledge, attitudes, behavior and diet of adolescent balanced nutrition, if adolescents are exposed to the media intensely and continuously. Providing the Remind me application media as a media for nutritional education to adolescents still needs to be developed in an effort to perfect the application display, content, specifications of mobile phones or smart phones, better programming system specifications and safer domain server usage will reduce debugging on the application system, so that the mes- sage delivered and can be achieved.
Towards building theory on coachee readiness

Lack of coachee readiness impacts negatively on the effectiveness of coaching. Despite the general awareness of the phenomena that influence coachee readiness, this concept needs better description in the coaching literature. This article reports on a Critical Interpretive Synthesis (CIS) study of the factors that influence coachee readiness and consider ways to overcome this. This article seeks to contribute to the formulation of a theory on the concept of coachee readiness by developing a theoretical framework with the aim of guiding stakeholders at the pre-contemplation, contemplation, and preparation phases of a coaching assignment.
Individualized Binaural Technology: Measurement, Equalization and Perceptual Evaluation

In this work the importance of individualization in binaural technique is investigated. The results extend the present knowledge on the efficient measurement of individual head-related transfer functions (HRTFs) and highlight the importance of individual equalization filters in binaural reproduction, using both loudspeakers and headphones. Moreover, an integrated framework for the calculation of such equalization filters is presented. An innovative measurement setup was developed to allow the fast acquisition of individual HRTFs. The hardware was designed to be compatible with the range extrapolation technique, which makes the description of the HRTF’s distance-dependence possible. Major speedup was obtained by optimizing the multiple exponential sweep method. An individual HRTF dataset with approximately 4000 directions can be measured in less than 6 minutes with this new setup. Crosstalk cancellation (CTC) filters are required when playing back binaural signals via loudspeakers. To allow listeners to freely move their heads, switching between multiple loudspeakers is required and the CTC filters must be constantly updated according to the tracked head position. Filter calculations are carried out in frequency-domain for speed reasons. To impose causality constraints to the regularized frequency-domain calculations, a CTC filter calculation framework was proposed, which incorporates a new approach for the multi-channel minimum-phase regularization. This framework also addresses the switching between active loudspeakers through the use of a weighted filter calculation. A sound localization test showed that individualized CTC systems provided performance similar to that from binaural listening while nonindividualized CTC systems provided significantly lower localization performance. To deliver an authentic auditory impression without additional spectral coloration, binaural reproduction via headphones must be adequately equalized. Such equalization filters are obtained by inverting the headphone transfer function, which varies among listeners and individual fitting. To cope with these variations, a robust individual headphone equalization method was proposed. Perceptual tests showed that, in all but one of the tested situations, no audible differences between the original sound source and its binaural auditory display could be perceived.
Synergetic measures to contain highly transmissible variants of SARS-CoV-2 1

Background The public and scientific discourse on how to mitigate the COVID-19 pandemic is 14 often focused on the impact of individual protective measures, in particular on vaccination. In 15 view of changing virus variants and conditions, however, it seems not clear if vaccination or any 16 other protective measure alone may suffice to contain the transmission of SARS-CoV-2. 17 Methods Here, we investigate the effectiveness and synergies of vaccination and non18 pharmaceutical interventions like masking, distancing & ventilation, testing & isolation, and 19 contact reduction as a function of compliance in the population. Our new analysis accounts for 20 the practical compliance in the population and for both droplet transmission and aerosol 21 transmission. 22 Findings For realistic conditions, we find that it would be difficult to contain highly contagious 23 SARS-CoV-2 variants by any individual measure. Instead, we show how multiple synergetic 24 measures have to be combined to reduce the effective reproduction number (Re) below unity for 25 different basic reproduction numbers ranging from the SARS-CoV-2 ancestral strain up to 26 measles-like values (R0 = 3 to 18). For R0 = 5 as reported for the Delta variant and ~70% 27 vaccination rate, the synergies of masking and distancing & ventilation with compliances around 28 30% appear sufficient to keep Re < 1. In combination with 2-3 tests per week, this would work 29 also at lower vaccination rates, e.g., in schools. 30 Interpretation If the Omicron variant were to reach R0 = 8, it could still be contained with the 31 synergetic measures outlined above. In case of measles-like transmissibilities (R0 = 12 to 18), 32 higher compliances and testing rates or additional measures like general contact reductions 33 would be required. The presented findings and approach can be used to design and communicate 34 efficient strategies for mitigating the COVID-19 pandemic. 35 Funding Max Planck Society. 36 37 . CC-BY-NC-ND 4.0 International license It is made available under a is the author/funder, who has granted medRxiv a license to display the preprint in perpetuity. (which was not certified by peer review) preprint The copyright holder for this this version posted December 23, 2021. ; https://doi.org/10.1101/2021.11. 24.21266824 doi: medRxiv preprint
Isolation of a Gene That Encodes a New Retinal Protein, Archaerhodopsin, from Halobacterium sp. aus- l*

We have cloned and sequenced the gene that encodes archaerhodopsin, a light-driven H+ pump in Halobacterium sp. aus-1 (Mukohata, Y., Sugiyama, Y., Ihara, K., and Yoshida, M. (1988) Biochem. Biophys. Res. Commun. 151, 1339-1345). The nucleotide sequence of this gene contained an open reading frame which corresponded to a protein of 260 amino acids with a molecular mass of 27,851 daltons, including a precursor sequence of 6 amino acids at the amino terminus and 2 amino acids at the carboxyl terminus. The deduced amino acid sequence of archaerhodopsin exhib- ited 59 and 32% homology to the sequences of bacteriorhodopsin and halorhodopsin, respectively, from Halobacterium halobium. Three charged residues (Asp-121, Asp-218, and Lys-222) are conserved in the transmembrane segments among the three retinal proteins. Residues Asp-91 and Asp-102 for the pumping of protons
A Case Series of Pulmonary Mucormycosis Caused by Rhizopus Microsporus

Mucormycosis is a relatively uncommon but intractable fungal infectious disease. The mortality is very high when it occurs. In this study, we reported a continuous cases of pulmonary mucormycosis in three patients who suffered from chronic kidney disease, history of renal transplantation and multiple myeloma in April 2017, respectively. Cultures were obtained from several specimens (pathological tissue, bronchoalveolar lavage fluid and sputum) and all identified as Rhizopus microsporus by Matrix-Assisted Laser Desorption Ionization Time-Of-Flight (MALDI-TOF) mass spectrometry and ITS DNA sequencing methods. In addition, they all showed susceptibility to amphotericin B and posaconazole. Unfortunately, even through the three patients all treated with amphotericin B and posaconazole, one man still died eventually. Clinicians should keep an eye on patients who are at high risk of acquiring this fatal disease and make early intervention strategies to reduce terrible outcomes.