Miracle-dz/UniFAR-FTUs huggingface dataset:
#ProtectNature—How Characteristics of Nature Conservation Posts Impact User Engagement on Facebook and Twitter

Social networks expand the communication tools of nature conservation. Nonetheless, to date there is hardly any scientific literature on nature conservation communication in social networks. For this reason, this paper examines 600 Facebook and Twitter posts of three German nature conservation organizations: Federal Agency for the Conservation of Nature (Bundesamt für Naturschutz, BfN), Naturschutzbund Deutschland e. V. (NABU), and World Wide Fund for Nature (WWF) Germany. Using the Mann–Whitney U method and Spearman’s rank correlation analysis, it reveals how post design affects communication success and provides respective recommendations for German conservation organizations. Communication success was divided into four indicators: reactions, comments, shares, and overall engagement as a synthesis of the three. On Facebook, the use of hashtags, images, and many characters (up to 1500) leads to higher success, whereas emojis and videos can reduce it. On Twitter, links, images, and longer posts promote user interactions. Emojis have a positive influence on comments and overall engagement, but a negative influence on reactions and shares. In addition, hashtags reduce overall engagement on Twitter. These results are discussed with reference to similar studies from other political fields in order to provide recommendations for conservation organizations. A validation and expansion of the presented results is recommended due to the growing relevance of digital nature conservation communication.
Modeling for 3-D Temperature Field of Oil-Immersed Transformer

The knowledge of temperature field of oil-filled transformer directly related to the judgment of overheated fault. There are mainly heat exchange, convection and their coupling in the transformer. Lot of traditional methods are not enough direct-viewing, and ignore the actual situation. The geometrical model of the transformer first modeled by Solidworks, and then ANSYS CFX is used to simulate the temperature field and flow field. Get a set of computer experiment result which can be reference. This computer experiment bring forth the method and effect of the simulate using that software, and make a foundation for the research of transformer overheated fault.
MODELING OF OCEAN THERMAL ENERGY CONVERSION (OTEC) PLANT IN REUNION ISLAND

Renewable Energy has a crucial interest for a remote area like Reunion Island. The supply of electricity based on renewable energy has many advantages but the major drawback is the production of electricity which varies highly according to the availability of the resource (wind, solar, wave, etc.). This causes a real problem for non interconnected electrical grid where intermittent renewable energies should be limited to a maximum of 30%. The ocean Thermal Energy Conversion (OTEC) provides an alternative of electricity production from the available energy of the oceans present all the time. By using surface hot water and deep cold water from the ocean, it is possible to operate a thermodynamics cycle, which will then generate electricity. In this article, in the first part a literary and technological review is carried out in two areas: electricity production and cooling of buildings with deep water. This study establishes a knowledge base on thermodynamic cycles consistent with the OTEC and on dimensional and functional parameters associated with this technology. Steady state simulations are presented to understand the operation of the system. Steady state models will evaluate the potential of the OTEC in distributing base electricity. These simulations will help evaluating the potential for new thermodynamic cycles such as the Kalina cycle. With these tools, a sensitivity study will evaluate the influence of different parameters on the cycle.Copyright © 2010 by ASME
Real-world experience of switching from tenofovir disoproxil fumarate to tenofovir alafenamide in patients with chronic hepatitis B: a retrospective study

Background Tenofovir alafenamide (TAF) has good viral suppression efficacy and less adverse effect than tenofovir disoproxil fumarate (TDF). Real-world studies on the antiviral efficacy and safety of switching from TDF to TAF in patients with chronic hepatitis B (CHB) are limited. Methods This retrospective study included 167 nucleos(t)ide analogue (NA)-naive patients with CHB. All the patients received TDF at least 12 months before switching and TAF at least 12 months after switching at a single medical center. The Friedman test with Dunn–Bonferroni post hoc tests and repeated-measures analysis of variance was used to analyze the effect of complete viral suppression, alanine aminotransferase (ALT) level normalization, renal function changes, body weight, and body mass index in the periods before and after switching. Results The mean age and TDF treatment duration were 52 ± 11 years and 2.8 years (interquartile range, 1.51–5.15 years), respectively. The complete viral suppression rate was similar between the time of switching and 48 weeks after switching to TAF (77.8% vs 76%, P = 1.000). The percentage of alanine aminotransferase (ALT) normalization increased from 26.3% at TDF start to 81.4% (P < 0.001) at time of switching and 89.2% at 48 weeks after switching to TAF (P = 0.428). The median estimated glomerular filtration rate decreased from 100.09 mL/min/1.73 m² at TDF start to 91.97 mL/min/1.73 m² (P < 0.001) at the time of switching and stabilized at 48 weeks after switching to TAF (93.47 mL/min/1.73m², P = 1.000). The body weight decreased from 69.2 ± 12.2 kg at TDF start to 67.4 ± 12.1 kg (P < 0.001) at the time of switching to TAF and returned to 68.7 ± 12.7 kg (P < 0.001) 48 weeks thereafter. The body mass index (BMI) decreased from 25 ± 3.3 kg/m² at TDF start to 24.5 ± 3.3 kg/m² (P = 0.002) at the time of switching to TAF and returned to 25.1 ± 3.6 kg/m² (P < 0.001) 48 weeks thereafter. Conclusions Our study showed that switching to TAF from TDF had good antiviral effectiveness and stabilized renal function. The body weight and BMI decreased during TDF therapy and regained after switching to TAF.
Role of Survivin in Bladder Cancer: Issues to Be Overcome When Designing an Efficient Dual Nano-Therapy

Bladder cancer is the 10th most diagnosed cancer, with almost 10 M cancer deaths last year worldwide. Currently, chemotherapy is widely used as adjuvant therapy after surgical transurethral resection. Paclitaxel (PTX) is one of the most promising drugs, but cancer cells acquire resistance, causing failure of this treatment and increasing the recurrence of the disease. This poor chemotherapeutic response has been associated with the overexpression of the protein survivin. In this work, we present a novel dual nano-treatment for bladder cancer based on the hypothesis that the inhibition of survivin in cancer cells, using a siRNA gene therapy strategy, could decrease their resistance to PTX. For this purpose, two different polymeric nanoparticles were developed to encapsulate PTX and survivin siRNA independently. PTX nanoparticles showed sizes around 150 nm, with a paclitaxel loading of around 1.5%, that produced sustained tumor cell death. In parallel, siRNA nanoparticles, with similar sizes and loading efficiency of around 100%, achieved the oligonucleotide transfection and knocking down of survivin expression that also resulted in tumor cell death. However, dual treatment did not show the synergistic effect expected. The root cause of this issue was found to be the cell cycle arrest produced by nuclear survivin silencing, which is incompatible with PTX action. Therefore, we concluded that although the vastly reported role of survivin in bladder cancer, its silencing does not sensitize cells to currently applied chemotherapies.
Mechanical strain energy shuttle for aircraft morphing via wing twist or structural deformation

Direct structural deformation to achieve aerodynamic benefit is difficult because large actuators must supply energy for structural strain and aerodynamic loads. This ppaer presents a mechanism that allows most of the energy required to twist or deform a wing to be stored in descrete springs. When this device is used, only sufficient energy is provided to control the position of the wing. This concept allows lightweight actuators to perform wing twisting and other structural distortions, and it reduces the onboard mass of the wing-twist system. The energy shuttle can be used with any actuator and it has been adapted for used with shape memory alloy, piezoelectric, and electromagnetic actuators.
Performance Analysis for Acoustic Echo Cancellation Systems based on Variable Step Size NLMS algorithms

Acoustic echo cancellation is an essential signal enhancement tool in hands‐free communication. Loudspeaker signals are picked up by a microphone and are fed back to the correspondent, resulting in an undesired echo. Nowadays, adaptive filtering techniques are typically employed to suppress this echo. In acoustic applications long filters need to be adapted for sufficient echo suppression. Classical adaptation schemes such as LMS are quite expensive for accurate echo path modeling in highly reverberating environments. In order to cope with dynamic signals, step‐size μ is often normalized by taking it inversely proportional to the energy of x. This normalized version of LMS (NLMS) is typically used in practice. This paper discusses various variable step‐size NLMS based algorithms which can be implemented in acoustic echo cancelling applications. The performance of these algorithms in terms of ERLE and NSEC curves are obtained and comparison between them is done. Also a simple and novel Double‐Talk Detectio.
The complete chloroplast genome of Artemisia Montana (Nakai) Pamp. (Asteraceae), a traditional medicinal herb in Korea

Abstract Artemisia Montana (Nakai) Pamp. is a widely used heath food and a well-known traditional Korean herbal medicine. The complete chloroplast genome sequence of A. Montana was determined using high-throughput sequencing technology. Chloroplast genome was 151,133 bp in length, with a large single-copy (LSC) region of 98,497 bp, a small single-copy (SSC) region of 18,352 bp, separated by two inverted repeat (IR) regions of 17,142 bp each. It contained a total of 113 genes, with an overall GC content of 37.5%. The phylogenetic analysis showed that A. montana most closely related to A. feddei. This result will enrich the genetic resources of medicinal plant and useful for future investigation of genetics, evolution and identification of Artemisia species.
Genetic Diversity in Natural Populations and Cultivated Stands of Walnut (Juglans regia L.) Using Microsatellite Marker

: Information on genetic diversity is fundamental to developing in situ or ex situ conservation strategies. This study assessed the genetic differentiation between plantations and neighboring natural populations of Juglans regia . Genetic structures of three natural population and three neighboring plantations of J. regia in northwest of Iran were assessed using 10 nuclear microsatellite loci (SSR). Natural populations presented higher total number of alleles (119) and observed heterozygosity (Ho= 0.29) than planted stands (101 alleles, Ho= 0.21). The observed alleles of natural stands varied from 2 (WGA61 and WGA9) to 7 (WGA9) and from 2 (WGA321 and WGA276) to 5 (WGA202 and WGA9) in planted stands. One of the planted populations (B) indicated the largest level of genetic diversity. In conclusion, genetic diversity of all investigated plantation and natural stands are similar. This recommends that even plantations might qualify as gene conservation stands.
Exploring the Influences of Point-of-Interest on Traffic Crashes during Weekdays and Weekends via Multi-Scale Geographically Weighted Regression

Some studies on the impact of traditional land use factors on traffic crashes do not take into account the limitations of spatial heterogeneity and spatial scale. To overcome these limitations this study presents a systematic method based on multi-scale geographically weighted regression (MGWR), which considers spatial heterogeneity and spatial scale differences of different influencing factors, to explore the influence of reclassified points-of-interest (POI) on traffic crashes occurring on weekdays and weekends. Experiments were conducted on 442 communities in Hankou, Wuhan, and the performance of the proposed method was compared against traditional methods based on ordinary least squares (OLS), spatial lag model (SLM), spatial error model (SEM), and geographically weighted regression (GWR). The experiments show that the proposed method yielded the best fitness of models and more accurate model results of local coefficient estimates. The highlights of the results are as follows: There are differences in the scale of the predictor variables. Residential POI, scenic POI, and transportation POI have a global effect on traffic crashes. Commercial service POI and industrial POI affects traffic crashes at the regional scale, while public service POI affects crashes at the local scale. The local coefficient estimates from residential POI and scenic POI have little impact on traffic crashes. During weekdays, more transportation POI in the entire study area leads to more traffic crashes. While on weekends, transportation POI has a significant positive effect on crashes only in some communities. The local coefficient estimates for industrial POI vary at different periods. Commercial service POI and public service POI may increase the risk of crashes in some communities, which can be observed on weekdays and weekends. Exploring the influence of POI on traffic crashes at different periods is helpful for traffic management strategies and in reducing traffic crashes.
Psychological self-security and self-concept among Saudi epilepsy patients at a tertiary care center in KSA

Objective: While psychological issues in epilepsy patients have been studied extensively, the phenomena of self-concept and self-security have not been adequately addressed in such patients. Therefore, the aim of the current study is to assess the levels of psychological self-security and self-concept among Saudi epilepsy patients. Methods: A case-control study was conducted on adult patients with epilepsy from the Epilepsy Monitoring Unit at King Fahad Medical City in Riyadh, Saudi Arabia. Healthy controls were obtained from the community. Demographic data including age, gender and education level were collected. Self-concept and self-security were assessed using validated scales. Descriptive statistics were obtained, and inferential testing was conducted. Results: Data from 145 subjects was entered in the final analysis, including 100 patients with epilepsy and 45 controls (females = 32%). A significantly higher level of psychological insecurity was found in PWE (people with epilepsy) compared to controls. No significant difference was noticed on self-concept level between PWE versus controls. Education level was significantly lower in PWE than in controls. Those with higher education levels scored lower on psychological insecurity, although this effect disappeared when the data were split by health status. Conclusion: Level of psychological self-security was higher in PWE than controls, while no difference in self-concept was observed. This study highlights the areas of focus needed in epilepsy-related social services in order to improve the psychological wellbeing of patients with epilepsy.
An integrative review of the built environment discipline's role in the development of society's resilience to disasters

Purpose – The purpose of this paper is to present an integrative review of the literature to explore the nature of the built environment discipline's potential role in the development of society's resilience to disasters.Design/methodology/approach – The integrative literature review method is used to address this emerging topic and present a holistic conceptualisation of the literature. For the purpose of this review, the Business Source Premier (EBSCO), Emerald Management eJournals, Management & Organization Studies (CSA) and Science Direct (Elsevier) electronic databases are the main source for identifying studies, along with conference proceedings from the events of major built environment and disaster‐related networks.Findings – A review of the literature reveals that the built environment “discipline”, at each stage of the disaster management process, has invaluable expertise and a key role to play in the development of society's resilience to disasters. However, the collaborative definition of the .
A Simulation Method of Pressure-Stress Affects Power Press Pack FRD Chip Forward Voltage

Press Pack IGBTs modules have the characteristics of easy series connection and double side cooling widely used in industry, electric power, smart grid and other fields. Press Pack FRD (Fast Recovery Diode) chips is a component of Press Pack IGBTs module. In the actual operating conditions, the electrical parameters of FRD device will change in the electrical properties under pressure-stress, especially the Forward Voltage (VF) parameters. This change of the VF parameters will have adverse effect on the reliability of FRD chip and the overall module. In this paper, according to the stress of physical model of semiconductor material silicon were analyzed, proposed method to stress effect on the VF parameter of the FRD simulation analysis software.
Uncovering Heterogeneous Regional Impacts of Chinese Monetary Policy

This paper applies causal machine learning methods to analyze the heterogeneous regional impacts of monetary policy in China. The method uncovers the heterogeneous regional impacts of different monetary policy stances on the provincial figures for real GDP growth, CPI inflation and loan growth compared to the national averages. The varying effects of expan-sionary and contractionary monetary policy phases on Chinese provinces are highlighted and explained. Subsequently, applying interpretable machine learning, the empirical results show that the credit channel is the main channel affecting the regional impacts of monetary policy. An imminent conclusion of the uneven provincial responses to the “one size fits all” monetary policy is that different policymakers should coordinate their efforts to search for the optimal fiscal and monetary policy mix.
ONLINE COMMUNITIES: CHALLENGES AND OPPORTUNITIES FOR SOCIAL NETWORK RESEARCH

Online communities form a challenging and still-evolving field for social network research. We highlight two themes that are at the core of social network literature: formative processes and structures, and discuss how these might be relevant in the context of online communities. Processes of tie formation might evolve differently in online communities. Second, we discuss how network structures emerge in different ways than previously studied, and should therefore be interpreted differently.
Simulation Analysis of the Effects of Maintenance Policies on Manufacturing Line Productivity

A manufacturing line consists of a series of machines, which are subject to failures due to component deterioration and other random causes. While failures due to random causes are inevitable and need corrective maintenance (CM), failures due to component deterioration can be avoided by preventive maintenance (PM). Both types of maintenances can cause significant production losses, particularly if a proper PM policy is not practiced. Productivity calculations of multi-stage lines with storage units and maintenance operations can be quite complex. Furthermore, closed form solutions in equation forms are not possible when both preventive and corrective maintenances are incorporated into the model. In this paper, a simulation model is presented for a multi-stage line and line productivity is evaluated under different operating conditions and maintenance policies.
Resistance Prediction for Hard Chine Hulls in the Pre-Planing Regime

Abstract A mathematical representation of calm-water resistance for contemporary planing hull forms based on the USCG and TUNS Series is presented. Regression analysis and artificial neural network (ANN) techniques are used to establish, respectively, Simple and Complex mathematical models. For the Simple model, resistance is the dependent variable (actually R/Δ for standard displacement of Δ = 100000 lb), while the Froude number based on volume (FnV) and slenderness ration (L/V1/3) are the independent variables. In addition to these, Complex model’s independent variables are the length beam ratio (L/B), the position of longitudinal centre of gravity (LCG/L) and the deadrise angle (β). The speed range corresponding to FnV values between 0.6 and 3.5 is analyzed. The Simple model can be used in the concept design phases, while the Complex one might be used for various numerical towing tank performance predictions during all design phases, as appropriate
Essential Role for an Isoform of Escherichia coli Translation Initiation Factor IF2 in Repair of Two-Ended DNA Double-Strand Breaks

Double-strand breaks (DSBs) in DNA are major threats to genome integrity. In Escherichia coli, DSBs are repaired by RecA- and RecBCD-mediated homologous recombination (HR). ABSTRACT In Escherichia coli, three isoforms of the essential translation initiation factor IF2 (IF2-1, IF2-2, and IF2-3) are generated from separate in-frame initiation codons in infB. The isoforms have earlier been suggested to additionally participate in DNA damage repair and replication restart. It is also known that the proteins RecA and RecBCD are needed for repair of DNA double-strand breaks (DSBs) in E. coli. Here, we show that strains lacking IF2-1 are profoundly sensitive to two-ended DSBs in DNA generated by radiomimetic agents phleomycin or bleomycin, or by endonuclease I-SceI. However, these strains remained tolerant to other DSB-generating genotoxic agents or perturbations to which recA and recBC mutants remained sensitive, such as to mitomycin C, type-2 DNA topoisomerase inhibitors, or DSB caused by palindrome cleavage behind a replication fork. Data from genome-wide copy number analyses following I-SceI cleavage at a single chromosomal locus suggested that, in a strain lacking IF2-1, the magnitude of recombination-dependent replication through replication restart mechanisms is largely preserved but the extent of DNA resection around the DSB site is reduced. We propose that in the absence of IF2-1 it is the synapsis of a RecA nucleoprotein filament to its homologous target that is weakened, which in turn leads to a specific failure in assembly of Ter-to-oriC directed replisomes needed for consummation of two-ended DSB repair. IMPORTANCE Double-strand breaks (DSBs) in DNA are major threats to genome integrity. In Escherichia coli, DSBs are repaired by RecA- and RecBCD-mediated homologous recombination (HR). This study demonstrates a critical role for an isoform (IF2-1) of the translation initiation factor IF2 in the repair of two-ended DSBs in E. coli (that can be generated by ionizing radiation, certain DNA-damaging chemicals, or endonuclease action). It is proposed that IF2-1 acts to facilitate the function of RecA in the synapsis between a pair of DNA molecules during HR.