Miracle-dz/UniFAR-FTUs huggingface dataset:
Out-of-sequence measurement processing for tracking ground target using particle filters

We present a filtering algorithm for processing out-of-sequence measurements (OOSMs) in multi-sensor target tracking using the particle filter (PF). Measurements can arrive out-of-sequence at a fusion center due to varying data pre-processing times at the sensor platforms and communication delays in a multi-sensor target tracking system. Standard filtering algorithms such as the Kalman filter (KF), extended KF (EKF), interacting multiple model (IMM) filter, and PF cannot be directly applied to process the OOSM. Processing of the OOSM requires new algorithms within the framework of KF, EKF, IMM, or PF. The ground moving target indicator (GMTI) radar sensors play an important role in the military and commercial domain such as surveillance of ground moving targets and air traffic control. The GMTI measurement model is a nonlinear function of the target state. Therefore, extension of the existing linear OOSM filtering algorithms to the GMTI filtering problem with OOSMs would require EKF type linearization and hence would be sub-optimal. As a superior alternative to the EKF, the PF has been successfully applied to a number of nonlinear filtering problems where the EKF or IMM using EKF is sub-optimal. Our OOSM PF algorithm does not require a large amount of storage and preliminary results based on numerical simulations show that the algorithm yields results comparable to previous algorithms.
A phosphorus‐limitation induced, functionally conserved DUF506 protein is a repressor of root hair elongation in plants

Summary Root hairs (RHs) function in nutrient and water acquisition, root metabolite exudation, soil anchorage and plant–microbe interactions. Longer or more abundant RHs are potential breeding traits for developing crops that are more resource‐use efficient and can improve soil health. While many genes are known to promote RH elongation, relatively little is known about genes and mechanisms that constrain RH growth. Here we demonstrate that a DOMAIN OF UNKNOWN FUNCTION 506 (DUF506) protein, AT3G25240, negatively regulates Arabidopsis thaliana RH growth. The AT3G25240 gene is strongly and specifically induced during phosphorus (P)‐limitation. Mutants of this gene, which we call REPRESSOR OF EXCESSIVE ROOT HAIR ELONGATION 1 (RXR1), have much longer RHs, higher phosphate content and seedling biomass, while overexpression of the gene exhibits opposite phenotypes. Co‐immunoprecipitation, pull‐down and bimolecular fluorescence complementation (BiFC) analyses reveal that RXR1 physically interacts with a RabD2c GTPase in nucleus, and a rabd2c mutant phenocopies the rxr1 mutant. Furthermore, N‐terminal variable region of RXR1 is crucial for inhibiting RH growth. Overexpression of a Brachypodium distachyon RXR1 homolog results in repression of RH elongation in Brachypodium. Taken together, our results reveal a novel DUF506‐GTPase module with a prominent role in repression of plant RH elongation especially under P stress.
Interaction between pesticides applied alone or in mixtures in corn

Abstract The objective of this work was to evaluate the selectivity of herbicides applied alone or in tank mix, and also of combinations of different classes of pesticides (fungicides, herbicides and insecticides) on corn. An experiment was installed in the 2017/18 crop to assess herbicide selectivity, and repeated in 2018/19. The second experiment aimed to assess the selectivity of mixtures of different classes of pesticides, and was installed only in 2017/18. The experimental design adopted in the tests was randomized blocks, with four replicates. In each trial, a total of 16 treatments were evaluated, plus a control. At 7, 14 and 21 days after the application of treatments the phytotoxicity to corn was evaluated and the yield components and grain yield were determined. Herbicides caused low levels of injury to the corn plants, with small variations in yield components, and affected crop yield differently. The mixtures of pesticides promoted low phytotoxicity, affected yield components inconsistently and caused changes in corn yield. Although these herbicides and other pesticides are registered for use in corn crops, application alone or in tank mix of certain molecules can cause losses in grain yield.
Prevalence of inadequate intake of folate in the post-fortification era: data from the Brazilian National Dietary Surveys 2008–2009 and 2017–2018

Abstract The objectives were to compare the evolution of dietary folate intake, to estimate the prevalence of folate inadequacy (POFI) and the contribution of food groups to folate intake (dietary folate plus folic acid from fortified foods) in two post-fortification periods in the Brazilian population, according to life stages, geographic regions and per capita income. Population-based study including representative data from the National Dietary Survey – Brazilian Household Budget Surveys (NDS-HBS) 2008–2009 and 2017–2018, with a total of 32 749 (2008–2009) and 44 744 (2017–2018) individuals aged ≥ 10 years old, excluding pregnant and lactating women. The National Cancer Institute method was used to estimate the distributions of usual dietary folate intake. POFI was estimated according to estimated average requirement cut-off point method. After 10 years of the first NDS-HBS, POFI has increased in all sex-age groups, except for 10–13 years. POFI among women of reproductive age was around 30 and 40 % in 2008–2009 and 2017–2018. Higher POFI was observed in the North region. The top five food groups contributors to folate intake in Brazil were beans, breads, pasta and pizza, cakes and cookies and non-alcoholic beverages groups in both periods, differing in the rank order of the last two groups. Although being a country that has adopted mandatory folic acid flour fortification for almost two decades, increased POFI was observed in 2017–2018. This study brings significant scientific information, which can help understand folate dietary data in different contexts and consequently guide the approach for public health fortification strategies.
The Challenges of Big Data for Research Ethics Committees: A Qualitative Swiss Study

Big data trends in health research challenge the oversight mechanism of the Research Ethics Committees (RECs). The traditional standards of research quality and the mandate of RECs illuminate deficits in facing the computational complexity, methodological novelty, and limited auditability of these approaches. To better understand the challenges facing RECs, we explored the perspectives and attitudes of the members of the seven Swiss Cantonal RECs via semi-structured qualitative interviews. Our interviews reveal limited experience among REC members with the review of big data research, insufficient expertise in data science, and uncertainty about how to mitigate big data research risks. Nonetheless, RECs could strengthen their oversight by training in data science and big data ethics, complementing their role with external experts and ad hoc boards, and introducing precise shared practices.
An Analysis of Lower Leg Impactor Behavior by Physics Model

This paper describes development of a lumped mass-spring model of lower leg subsystem test of the European Enhanced Vehicle-safety Committee WG17 (here after referred as to the EEVC WG17) test method in order to provide relationship among the stiffness of the vehicle under the test, knee-bending angle and upper tibia acceleration of the lower leg subsystem impactor. The lower leg subsystem test and protection criteria are intended to protect against knee joint injuries and lower leg bone fracture. The knee-bending angle of the lower leg subsystem impactor was shown as a function of the stiffness of the vehicle under the test. The lumped mass-spring model results indicated that upper bumper stiffness forms a significant component of the knee-bending angle and lower bumper stiffness forms a significant component of upper tibia acceleration similar to upper bumper stiffness.
Optimal mechanical force‐velocity profile for sprint acceleration performance

The aim was to determine the respective influences of sprinting maximal power output ( PHmax ) and mechanical Force‐velocity (F‐v) profile (ie, ratio between horizontal force production capacities at low and high velocities) on sprint acceleration performance. A macroscopic biomechanical model using an inverse dynamics approach applied to the athlete's center of mass during running acceleration was developed to express the time to cover a given distance as a mathematical function of PHmax and F‐v profile. Simulations showed that sprint acceleration performance depends mainly on PHmax , but also on the F‐v profile, with the existence of an individual optimal F‐v profile corresponding, for a given PHmax , to the best balance between force production capacities at low and high velocities. This individual optimal profile depends on PHmax and sprint distance: the lower the sprint distance, the more the optimal F‐v profile is oriented to force capabilities and vice versa. When applying this model to the data of 231 athletes from very different sports, differences between optimal and actual F‐v profile were observed and depend more on the variability in the optimal F‐v profile between sprint distances than on the interindividual variability in F‐v profiles. For a given sprint distance, acceleration performance (<30 m) mainly depends on PHmax and slightly on the difference between optimal and actual F‐v profile, the weight of each variable changing with sprint distance. Sprint acceleration performance is determined by both maximization of the horizontal power output capabilities and the optimization of the mechanical F‐v profile of sprint propulsion.
Comparison of SAR distribution of hip and knee implantable devices in 1.5T conventional cylindrical‐bore and 1.2T open‐bore vertical MRI systems

There is increasing use of open‐bore vertical MR systems that consist of two planar RF coils. A recent study showed that the RF‐induced heating of a neuromodulation device was much lower in the open‐bore system at the brain and the chest imaging landmarks. This study focused on the hip and knee implants and compared the specific absorption rate (SAR) distribution in human models in a 1.2T open‐bore coil with that of a 1.5T conventional birdcage coil.
Molecular characterization of circulating avian metapneumovirus, subgroup B, in broiler chickens, Iran, 2016-2018.

Background Avian metapneumovirus (aMPV) infection has significant economic impacts on the poultry industry all around the world. Aims The aim of this study is molecular investigations of different types of aMPV in broiler farms in different provinces of Iran from 2016 to 2018. Methods Tracheal and oropharyngeal swabs were collected from two hundred broiler chickens with respiratory signs in ten provinces of Iran, including Kurdistan, West Azerbaijan, Semnan, Esfahan, Sistan and Baluchistan, Qazvin, Khuzestan, Fars, Gilan, and Khorasan Razavi from February 2016 to December 2018. After RNA extraction, the presence of aMPV was confirmed using N gene special primers. Then, subtype-specific primers were utilized to differentiate the specific subtype. All positive samples were sequenced. Results As a general trend, the percentage of aMPV positive chickens increased gradually over time. All samples were clustered together and placed in the subtype B aMPV group. Although 2 samples from 2016 and 2 samples from 2018 were placed in a separate branch, most of the current study samples of 2016, 2017, and 2018 revealed six segregated sub-branches, and they were placed close to other isolates of 2011 and 2013 from Iran. Conclusion The current field study indicated the presence of aMPV in a considerable number of areas in Iran. Thus, the role of this virus in broiler respiratory complex should not be neglected.
Soluble Lectin-Like Oxidized Low-Density Lipoprotein Receptor-1 Level is Related to Clinical Prognosis In Patients with Acute Atherosclerosis-related Ischemic Stroke

To investigate the associations between soluble Lectin-like Oxidized Low-density lipoprotein receptor-1 (sLOX-1) and clinical prognosis, especially infarct volume in patients with acute atherosclerosis-related ischemic stroke. We recruited acute ischemic stroke patients within 3 days after onset. Patients were stratified into 3 groups by sLOX-1 level. Initial stroke severity was assessed using the National Institutes of Health Stroke Scale scores, and infarct volume was measured using DWI by ITK-SNAP software. The clinical prognosis was evaluated by DWI volume, clinical response at discharge, and functional outcome at 90 days. Spearman rank correlation analysis was used to examine associations between circulating sLOX-1 levels and infarct volumes. Logistic regression was used to explore the relationship between sLOX-1 levels and clinical prognosis. A total of 207 patients were included in our study. The median DWI volume in the lowest sLOX-1 tertile was 1.98 cm3, smaller than 4.26 cm3 in the highest sLOX-1 group. The Spearman rank correlation coefficient between sLOX-1 levels and DWI volume was 0.47 (P < .01). Compared with the highest sLOX-1 tertiles, patients in the lowest sLOX-1 tertile had a higher risk of favorable functional outcome at 90 days (OR = 3.47, 95% CI, 1.21-9.96) after adjusting traditional risk factors. However, there was no difference between sLOX-1 level and clinical response at discharge. For patients with acute atherosclerosis-related ischemic stroke, circulating sLOX-1 level is correlated with DWI volume in the acute phase and favorable functional outcome at 90 days, but not with the clinical response at discharge.
Exploring the Optimal Factor Structure of the Five Facet Mindfulness Questionnaire: Associations Between Mindfulness Facets and Dimensions of Psychopathology

Abstract Recent studies of the Five Facet Mindfulness Questionnaire (FFMQ) and its condensed version (FFMQ-SF) fail to replicate the initially proposed five-factor structure in clinical samples. Failure to adequately understand the dimensionality of common mindfulness measures within clinical samples, therefore, represents an important gap in the current literature. The increasing popularity of mindfulness-based interventions warrants further investigation of differential associations between facets of mindfulness and different forms of psychopathology. We examined (a) the underlying structure of the FFMQ and FFMQ-SF, and (b) associations between FFMQ and FFMQ-SF facets and dimensions of psychopathology (i.e., internalizing and substance use disorders) in two large clinical samples (N = 2,779). Results from bass-ackwards analyses suggested similarly defensible five- and six-factor model solutions in terms of fit. The five-factor model was optimal when factoring in parsimony. Exploratory structural equation modeling revealed that all FFMQ facets with the exception of observe were negatively associated with the internalizing factor. Associations with substance use disorders were more complex. In both samples, five-factor FFMQ and FFMQ-SF models were determined to best represent these data. Whereas deficits in all FFMQ facets with the exception of observe correspond with lower internalizing psychopathology, a more nuanced association was observed with substance use disorders.
The correlation between levels of prenatal attachment and styles coping with stress in pregnant women

ABSTRACT Background Pregnancy is a very important period in the development of attachment. Objective To determine the correlation between prenatal attachment levels of healthy pregnant women and their styles of coping with stress and those of high-risk pregnant women. Method This descriptive study consisted of 76 women in their third-trimester of pregnancy hospitalised at the Obstetrics and Gynaecology service at a hospital and 210 women in their third-trimester of pregnancy who were experiencing a healthy pregnancy process and admitted to the Gynaecology Outpatient Clinic for pregnancy follow-up. The data were collected with the Personal Information Form, the Prenatal Attachment Inventory and the Stress Coping Styles Scale. Results There was a statistically significant difference between the prenatal attachment levels of healthy and high-risk pregnant women. There was a positive correlation between the prenatal attachment levels and the self-confident and optimistic approaches among the styles of coping with stress in the healthy and high-risk pregnant women . Conclusion The attachment levels of the high-risk pregnant women were higher than were those of the healthy pregnant women. As the use of the self-confident and optimistic approach styles in coping with stress increases among healthy and high-risk pregnant women, so do their prenatal attachment levels.
Healthcare Provider Analogies as Memorable Messages

Healthcare providers must explain medical information to patients in a way that patients can understand. Provider use of analogies is one strategy that may help patients better understand medical information. The present study, guided by a memorable message framework, investigated whether participants remembered any analogies used by their healthcare providers, and included a content analysis of the function the analogies served, the types of analogies participants remembered, and the body systems associated with the health issues that were described. Almost one-quarter of participants recalled an analogy used by a provider. The most frequently recalled analogies functioned to describe health conditions or phenomena, followed by elements of the body, and treatments or something external to the body. Analogies were most frequently used to describe health issues associated with the cardiovascular system, musculoskeletal system, digestive system, dental, eye, or skin issues, or the nervous system. The analogies were categorized as mechanical, a feeling or experience, random object, structure, food, nature, war/battle, or medical/body. Provider analogies may be a type of memorable message for some patients. Providers could consider using suitable analogies to explain health issues when communicating with patients, and be trained in effective use of analogies.
Bending of Canonical and G/T Mismatched DNAs

Mismatched base pairs alter the flexibility and intrinsic curvature of DNA. The role of such DNA features is not fully understood in the mismatch repair pathway. MutS/DNA complexes exhibit DNA bending, PHE intercalation, and changes of base-pair parameters near the mismatch. Recently, we have shown that base-pair opening in the absence of MutS can discriminate mismatches from canonical base pairs better than DNA bending. However, DNA bending in the absence of MutS was found to be rather challenging to describe correctly. Here, we present a computational study on the DNA bending of canonical and G/T mismatched DNAs. Five types of geometric parameters covering template-based bending toward the experimental DNA structure, global, and local geometry parameters were employed in biased molecular dynamics in the absence of MutS. None of these parameters showed higher discrimination than the base-pair opening. Only roll could induce a sharply localized bending of DNA as observed in the experimental MutS/DNA structure. Further, we demonstrated that the intercalation of benzene mimicking PHE decreases the energetic cost of DNA bending without any effect on mismatch discrimination.
Comparative Study on Temperature Stresses in Asphalt Material Using Nonlinear Viscoelastic Approach

An accurate estimate of temperature stress in asphalt pavements is an important consideration for colder regions. In asphalt, a viscoelastic material, the developed stress depends on the trend of temperature variation and the relaxation modulus of the asphalt mix. This paper presents a comparative study of the temperature stresses by considering different temperature profiles for the same temperature differential and different relaxation models for the same asphalt mix. A nonlinear viscoelastic approach was used for the stress calculation. From this study, it was concluded that both the temperature profile and the relaxation model significantly affect the stress profile. Also, for cases in which the rate of change of the temperature was nonlinear, the computed maximum stress value for a given temperature profile seemed to be different within few cycle periods.
Biceps Augmentation Outperforms Tear Completion Repair or In Situ Repair for Bursal-Sided Partial-Thickness Rotator Cuff Tears in a Rabbit Model

Background: There is an ongoing debate on the treatment of bursal-sided partial-thickness rotator cuff tears (PTRCTs), including ideal repair techniques. Augmentation using a collagen patch has been introduced as a new surgical approach to treat PTRCTs, while the effect of autogenous biceps augmentation (BA) has not been investigated. Purpose: To analyze the effects of BA on bursal-sided PTRCTs and compare its histological and biomechanical results with those of tear completion followed by repair and in situ repair (ISR). Study Design: Controlled laboratory study. Methods: Unilateral chronic PTRCTs were created in 96 mature New Zealand White rabbits, which were randomly divided into 4 groups: no repair, tear completion repair (TCR), ISR, and BA. A new bicipital groove was fabricated in BA for the biceps tendon that was transferred to augment the bursal-sided PTRCT repair. In each group, we sacrificed 6 rabbits for biomechanical testing of the whole tendon-to-bone complex (WTBC) and 6 for histological evaluation of bursal- and articular-sided layers at 6 and 12 weeks postoperatively. Healing responses between the biceps and new bicipital groove in the BA group were determined using histological analysis, and final groove morphologies were evaluated using micro–computed tomography. Results: The remaining tendon and enthesis in bursal-sided PTRCTs progressively degenerated over time. WTBCs of ISR exhibited a larger failure load than those of TCR, although better healing properties in the bursal-sided repaired site were achieved using TCR based on histological scores and superior articular-sided histological scores were observed using ISR. However, WTBCs of BA displayed the best biomechanical results and superior histological scores for bursal- and articular-sided regions. The new bicipital groove in BA remodeled over time and formed similar morphologies to a native groove, which provided a mature bone bed for transferred biceps tendon healing to augment bursal-sided PTRCTs. Conclusion: BA achieved better biomechanical and histological results for repairing bursal-sided PTRCTs as compared with TCR and ISR. When compared with that of TCR, the WTBC of ISR exhibited a higher failure load, showing histological superiority in the articular-sided repair and inferiority in the bursal-sided repair. Clinical Relevance: BA may be an approach to improve bursal-sided PTRCT repair in humans, which warrants further clinical investigation.