Miracle-dz/UniFAR-FTUs huggingface dataset:
Effects of Self-Regulation vs. External Regulation on the Factors and Symptoms of Academic Stress in Undergraduate Students

The SRL vs. ERL theory has shown that the combination of levels of student self-regulation and regulation from the teaching context produces linear effects on achievement emotions and coping strategies. However, a similar effect on stress factors and symptoms of university students has not yet been demonstrated. The aim of this study was to test this prediction. It was hypothesized that the level of student self-regulation (low/medium/high), in interaction with the level of external regulation from teaching (low/medium/high), would also produce a linear effect on stress factors and symptoms of university students. A total of 527 undergraduate students completed validated questionnaires about self-regulation, regulatory teaching, stress factors, and symptoms. Using an ex post facto design by selection, ANOVAs and MANOVAs (3 × 3; 5 × 1; 5 × 2) were carried out. The results confirmed that the level of self-regulation and the level of regulatory teaching jointly determined the level of stress factors and symptoms of university students. Once again, a five-level heuristic of possible combinations was configured to jointly determine university students’ level of academic stress. We concluded that the combination of different levels of student regulation and regulation from the teaching process jointly determines university students’ level of academic stress. The implications for university students’ emotional health, stress prevention, and well-being are established.
Is Single Cord Irradiation Going to Be a New Standard for T1a Glottic Carcinoma?

Purpose and Objective: To evaluate the disease-free survival, overall survival, dosimetric, and voice handicap index (VHI) results of T1a glottic invasive squamous cell carcinoma (SCC) patients who underwent hypofractionated single vocal cord irradiation (HSVCI). Materials and Methods: The data of 18 patients with stage T1a glottic SCC were collected prospectively and analyzed retrospectively between July 2016 and July 2019. Patients were immobilized using a custom-fitted thermoplastic face and shoulder mask in hyperextension position. The CT scan was performed with 1-mm-thick slices. A planned target volume (PTV) margin of 3 mm was given to clinical target volume (CTV) in all directions, and 13 organs at risk were identified. Patients were prescribed a total of 5760–5808 cGy in 15–16 fractions. Patients had daily cone-beam computed tomography (CBCT), and the treatment was carried out with the physician. VHI test was applied to patients before and at the end of radiotherapy (RT) and 1, 2, 3, 4, and 6 months after the completion of RT. Results: Local control and overall survival rate is 100% for a median of 18 months (6–44 months) of follow-up. A patient was diagnosed with 2nd primary lung cancer and active treatment still continues. All patients completed the treatment within the scheduled time. Grade 1–2 dysphagia and dermatitis occurred in all patients, and no grade 3 and above side effects were observed. The mean values of VHI were 37.00, 39.83, 38.28, 17.17, 12.22, 8.56, and 6.06 at the beginning of RT, at the end of RT, and 1, 2, 3, 4, and 6 months after RT, respectively. Conclusion: Compared to surgery and conventional laryngeal radiotherapy, HSVCI is an alternative treatment method for T1a glottic cancer by reducing the treatment time to 3 weeks, facilitating recurrence treatment, and providing effective sound quality without compromising local control. Considering that ~80% of recurrences in glottic cancer occur within the first 2 years, 100% local control in a median of 18 months is extremely successful, but long-term follow-up is essential to observe possible late side effects.
A Cold Environment Aggravates Cough Hyperreactivity in Guinea Pigs With Cough by Activating the TRPA1 Signaling Pathway in Skin

Cough exacerbation in cold environments is a characteristic feature of patients with chronic cough. There is consensus that inhalation of cold air stimulates cough receptors but this idea is not consistent with the fact that cold air is usually unable to directly enter the lower airway. To elucidate the effects of cold environments and transient receptor potential ankyrin 1 (TRPA1) on cough, we compared cough reactivity, airway inflammation, and TRPA1 expression in guinea pigs with chronic cough induced by the repeated inhalation of citric acid for 15 days. The guinea pigs were exposed to cold environments for three consecutive days from day 13 to 15. Repeated inhalation of citric acid increased cough reactivity to inhaled cinnamaldehyde. We found that exposure to cold environments further aggravated cough hyperreactivity in guinea pigs with chronic cough, but not in normal guinea pigs. Cough hyperreactivity was promoted when the whole body and trunk-limbs, but not the heads, of the guinea pigs were exposed to cold environments, and abolished by pretreating the skin through immersion in the TRPA1 antagonist, HC-030031. Substance P levels in bronchoalveolar lavage fluid, and TRPA1 expression in the trachea and skin, were increased in guinea pigs when the whole body and trunk-limbs, rather than the head, were exposed to cold environments. However, this trend was also abolished by pretreatment of the skin via immersion in HC-030031. Similar changes in TRPA1 expression were also detected in the sensory fibers of the trachea and skin, as identified by immunofluorescence and laser-scanning confocal microscopy analysis. These results suggest that exaggerated cough hyperreactivity induced by cold environments may be related to activation of the cold-sensing TRPA1 signaling pathway in the skin, rather than the inhalation of cold air.
The Neurophysiological Responses of Concussive Impacts: A Systematic Review and Meta-Analysis of Transcranial Magnetic Stimulation Studies

Aim: This systematic review and meta-analysis investigated neurophysiological responses using transcranial magnetic stimulation (TMS) following a concussion or sub-concussion. Methods: A systematic searching of relevant databases for peer-reviewed literature quantifying motor evoked potentials from TMS between 1999 and 2019 was performed. A meta-analysis quantified pooled data for measures including motor threshold, motor latency, and motor evoked potential amplitude and for inhibitory measures such as cortical silent period duration, short-interval intracortical inhibition (SICI), and long-interval intracortical inhibition (LICI) ratios. Results: Fifteen articles met the inclusion criteria. The studies were arbitrarily classified into the groups, based on time post-concussion, “acute” (subjects 0–3 months post-injury, n = 8) and “post-acute” (3 months−2 years post-concussion, n = 7). A TMS quality of study checklist rated studies from moderate to high in methodological quality; however, the risk of bias analysis found that the included studies were categorised as high risk of bias, particularly for a lack of allocation concealment and blinding of participants in the methodologies. A meta-analysis showed no differences in excitability measures, apart from a decreased motor threshold that was observed in the concussed group (SMD −0.28, 95% CI −0.51 to −0.04; P = 0.02) for the post-acute time frame. Conversely, all inhibitory measures showed differences between groups. Cortical silent period duration was found to be significantly increased in the acute (SMD 1.19, 95% CI 0.58–1.81; P < 0.001) and post-acute (SMD 0.55, 95% CI 0.12–0.98; P = 0.01) time frames. The SICI (SMD −1.15, 95% CI −1.95 to −0.34; P = 0.005) and LICI (SMD −1.95, 95% CI −3.04 to −0.85; P = 0.005) ratios were reduced, inferring increased inhibition, for the post-acute time frame. Conclusion: This systematic review and meta-analysis demonstrates that inhibitory pathways are affected in the acute period post-concussion. However, persistent alterations in cortical excitability remain, with increased intracortical inhibition. While TMS should be considered as a reliable technique to measure the functional integrity of the central nervous system, the high risk of bias and heterogeneity in data suggest that future studies should aim to incorporate standardised methodological techniques, particularly with threshold determination and stimulus intervals for paired-pulse measures.
Narrative practice may foster comfort but not enhance cognition in adult witness interviews about a mock sexual assault

ABSTRACT The present study tested the effectiveness of narrative practice on adult witnesses’ reports about a mock sexual assault. Narrative practice is a rapport-building activity that involves recounting a neutral or pleasant event prior to discussing the target topic. Engaging in narrative practice tends to enhance children’s reporting, but its utility with adults is unknown. Adults (n = 62) 18- to 62-years-old viewed a 7-minute video of a mock sexual assault and then were questioned with an open-ended protocol that began with narrative practice or not. Results showed that narrative practice did not appear to aid memory retrieval but may have increased comfort for some participants. Findings are discussed with regard to interviewing practice.
Role for Retinoic Acid-Related Orphan Receptor Alpha (RORα) Expressing Macrophages in Diet-Induced Obesity

The transcription factor RORα plays an important role in regulating circadian rhythm, inflammation, metabolism, and cellular development. Herein we show a role for RORα-expressing macrophages in the adipose tissue in altering the metabolic state of mice on a high-fat diet. The expression of Rora and RORA is elevated in white adipose tissue from obese mice and humans when compared to lean counterparts. When fed a high-fat diet Rora reporter mice revealed increased expression of Rora-YFP in macrophages in white adipose tissue deposits. To further define the potential role for Rora-expressing macrophages in the generation of an aberrant metabolic state Rorafl/flLysMCre/+ mice, which do not express Rora in myeloid cells, were maintained on a high-fat diet, and metabolic parameters assessed. These mice had significantly impaired weight gain and improved metabolic parameters in comparison to Rorafl/fl control mice. Further analysis of the immune cell populations within white adipose tissue deposits demonstrates a decrease in inflammatory adipose tissue macrophages (ATM). In obese reporter mouse there was increased in Rora-YFP expressing ATM in adipose tissue. Analysis of peritoneal macrophage populations demonstrates that within the peritoneal cavity Rora-expression is limited to myeloid-derived macrophages, suggesting a novel role for RORα in macrophage development and activation, which can impact on metabolism, and inflammation.
The Free Achilles Tendon Is Shorter, Stiffer, Has Larger Cross-Sectional Area and Longer T2* Relaxation Time in Trained Middle-Distance Runners Compared to Healthy Controls

Tendon geometry and tissue properties are important determinants of tendon function and injury risk and are altered in response to ageing, disease, and physical activity levels. The purpose of this study was to compare free Achilles tendon geometry and mechanical properties between trained elite/sub-elite middle-distance runners and a healthy control group. Magnetic resonance imaging (MRI) was used to measure free Achilles tendon volume, length, average cross-sectional area (CSA), regional CSA, moment arm, and T2* relaxation time at rest, while freehand three-dimensional ultrasound (3DUS) was used to quantify free Achilles tendon mechanical stiffness, Young’s modulus, and length normalised mechanical stiffness. The free Achilles tendon in trained runners was significantly shorter and the average and regional CSA (distal end) were significantly larger compared to the control group. Mechanical stiffness of the free Achilles tendon was also significantly higher in trained runners compared to controls, which was explained by the group differences in tendon CSA and length. T2* relaxation time was significantly longer in trained middle-distance runners when compared to healthy controls. There was no relationship between T2* relaxation time and Young’s modulus. The longer T2* relaxation time in trained runners may be indicative of accumulated damage, disorganised collagen, and increased water content in the free Achilles tendon. A short free Achilles tendon with large CSA and higher mechanical stiffness may enable trained runners to rapidly transfer high muscle forces and possibly reduce the risk of tendon damage from mechanical fatigue.
View Count of Online Videos Prediction Using Clustering View Count Patterns with Multivariate Linear Model

Social media of online video content should have some interesting applications, which provide convenience to users. For example, online advertising should be shown to the targeted users and the recommender system suggests appropriate videos to a user. Video view count prediction can help improve these recommendations because the video will be more interesting if it gets more view count. On YouTube, video view count and revenue are positively correlated. However, to correctly predict the view count of a video on YouTube, we divide problems into two issues. First, the view count has several patterns, which cause poor prediction. They should be grouped and trained specifically. Second, some patterns cause more errors in prediction because they are rare. Therefore, they should be separated to prevent overfitting. In this paper, we aim to design a model, which accurately predicts the short-term view count of videos on YouTube. We present F7NML (The First 7-day Normalization for clustering with Multivariate Linear model), a predictive model that can group the view count patterns and remove outliers. First, we grouped the patterns into many groups using the clustering model, which is presented in the paper. Then, we removed the groups of rare patterns, which are called outliers. Next, the video view count in the test dataset was matched to the groups using 1-nearest neighbor method. Finally, the Multivariate Linear model was trained for each group specifically. The experimental results show that F7NML with an appropriate clustering model could reduce error when it was compared to the best baseline model from the literature by about 27% on the 30th day view count prediction.
Competitive Advantage Improvement of Publishing Industry in Indonesia: A Case of PT. Gramedia Digital Nusantara

The changes in the business environment influenced by the growth of the global information system and technology development does not exclude changes mandated in book retail and publishing industry business model. Research on business model innovation emerge since the 2000s, but the research that analyzes its relation to how value chain and strategy may utilize one firm's competitive advantage is rare. Hence, this research fulfills the knowledge gaps, uses PT. Gramedia Digital Nusantara as a case study to analyze its business model and value chain. This research adopted the Osterwalder business model canvas, Porter's value chain model, and Porter's Generic Strategy to categorize the firm's competitive advantage improvement. Data collection research was conducted by converges in-depth interviews, data analysis for quantitative support, and observation results to answer the lack of in the firm's document. Then, the data were processed by using conventional qualitative data analysis techniques, open and axial coding. From the research, it can be concluded that the firm's competitive advantage is concerned about the efficiency resulted from internal key partners' collaboration, the utilization of advanced technology in marketing and production activities. Also, strengthen the customer segments with the firm through customer relationships supported by technology operations and research and insights activities.
MRP Transporters and Low Phytic Acid Mutants in Major Crops: Main Pleiotropic Effects and Future Perspectives

Phytic acid (PA) represents the major storage form of seed phosphate (P). During seed maturation, it accumulates as phytate salts chelating various mineral cations, therefore reducing their bioavailability. During germination, phytase dephosphorylates PA releasing both P and cations which in turn can be used for the nutrition of the growing seedling. Animals do not possess phytase, thus monogastric animals assimilate only 10% of the phytate ingested with feed, whilst 90% is excreted and may contribute to cause P pollution of the environment. To overcome this double problem, nutritional and environmental, in the last four decades, many low phytic acid (lpa) mutants (most of which affect the PA-MRP transporters) have been isolated and characterized in all major crops, showing that the lpa trait can increase the nutritional quality of foods and feeds and improve P management in agriculture. Nevertheless, these mutations are frequently accompanied by negative pleiotropic effects leading to agronomic defects which may affect either seed viability and germination or plant development or in some cases even increase the resistance to cooking, thus limiting the interest of breeders. Therefore, although some significant results have been reached, the isolation of lpa mutants improved for their nutritional quality and with a good field performance remains a goal so far not fully achieved for many crops. Here, we will summarize the main pleiotropic effects that have been reported to date in lpa mutants affected in PA-MRP transporters in five productive agronomic species, as well as addressing some of the possible challenges to overcome these hurdles and improve the breeding efforts for lpa mutants.
Morphometric Registration of Cytotoxic Changes of Epithelial Cells In Vitro: A Methodological Study

Quantification of toxicity-induced cytomorphological effects in an epithelial cell culture system is described. Estimates of volume density and star volume of mitochondria and lysosomes are given. Mean volumes (n = 5) and coefficients of variation of these parameters were equal in experimental (TPA-treatment) and control cultures. An optimal allocation of resources for estimating cytomorphometric parameters would be to increase the number of culture flasks.
Wireless Channel Modeling Analysis and Evaluation for Single Pilot Operation

In the next generation of avionics remote control systems, the reliability of air-to-ground (AG) communication link is crucial. In the system design procedure, the knowledge of the wireless channel plays a fundamental role since it influences the selection of the communication chain components. Accordingly, the proper modeling of the propagation phenomena helps the designer to select the appropriate technology and to tune the parameters (e.g. power transmission, working frequency, the amplifier noise figure, etc.) to fulfill the system requirements. This work performs a survey and an analysis of AG wireless channel models present in literature for providing recommendations to select and to apply them in budget-link computation.
Genomic Adaptation of Saccharomyces Species to Industrial Environments

The budding yeast has been extensively studied for its physiological performance in fermentative environments and, due to its remarkable plasticity, is used in numerous industrial applications like in brewing, baking and wine fermentations. Furthermore, thanks to its small and relatively simple eukaryotic genome, the molecular mechanisms behind its evolution and domestication are more easily explored. Considerable work has been directed into examining the industrial adaptation processes that shaped the genotypes of species and hybrids belonging to the Saccharomyces group, specifically in relation to beverage fermentation performances. A variety of genetic mechanisms are responsible for the yeast response to stress conditions, such as genome duplication, chromosomal re-arrangements, hybridization and horizontal gene transfer, and these genetic alterations are also contributing to the diversity in the Saccharomyces industrial strains. Here, we review the recent genetic and evolutionary studies exploring domestication and biodiversity of yeast strains.
Phase equilibria in the CaO-La2O3-Nb2O5 system at 1823, 1773, and 1673 K

ABSTRACT Phase equilibria in the CaO-La2O3-Nb2O5 system are of great significance for the utilization and application of rare earth and Nb resources. In the present work, the phase equilibria in high w(Nb2O5) corner of the CaO-La2O3-Nb2O5 system were studied by high-temperature equilibrium and quenching technology. Based on the continuity of phase diagram, a “Concavity and Convexity Rule” was proposed to predict the reasonable range of the unknown liquidus line. Finally, the isothermal sections and liquidus projection of the CaO-La2O3-Nb2O5 phase diagram were constructed, which include the primary phase fields of CaNb2O6, LaNbO4, Ca2Nb2O7, (Ca, Nb, La)O, and related liquidus lines at 1823, 1773, and 1673 K. Moreover, the subsolidus phase field of (Ca, Nb, La)O-LaNbO4-Ca2Nb2O7 with peritectic nonvariant reaction and CaNb2O6-LaNbO4-Ca2Nb2O7 with eutectic nonvariant reaction were determined, respectively.
Improved Algorithms for Alternating Matrix Space Isometry: From Theory to Practice

Motivated by testing isomorphism of p-groups, we study the alternating matrix space isometry problem (AltMatSpIso), which asks to decide whether two m-dimensional subspaces of n×n alternating (skew-symmetric if the field is not of characteristic 2) matrices are the same up to a change of basis. Over a finite field 𝔽_p with some prime p≠2, solving AltMatSpIso in time p^O(n+m) is equivalent to testing isomorphism of p-groups of class 2 and exponent p in time polynomial in the group order. The latter problem has long been considered a bottleneck case for the group isomorphism problem. Recently, Li and Qiao presented an average-case algorithm for AltMatSpIso in time p^O(n) when n and m are linearly related (FOCS '17). In this paper, we present an average-case algorithm for AltMatSpIso in time p^O(n+m). Besides removing the restriction on the relation between n and m, our algorithm is considerably simpler, and the average-case analysis is stronger. We then implement our algorithm, with suitable modifications, in Magma. Our experiments indicate that it improves significantly over default (brute-force) algorithms for this problem.
Undergraduate Engineering Students’ Types and Quality of Knowledge Used in Synthetic Modeling

Abstract Modeling is an important element of discovery and design processes because it can help individuals to comprehend and facilitate solutions to problems, mediate among mental and external representations, and off-load cognitive demands. However, engaging in model generation, comprehension, and transformation requires the orchestration of domain knowledge, meta-representational cknowledge, and various reasoning processes. This study aims to understand the interplay between domain knowledge, meta-representational knowledge, and students’ reasoning processes while engaging in modeling activity. Specifically, our goal is to investigate: (a) the types and quality of knowledge students used when performing modeling activities, and (b) the differences in types of knowledge used by students regarding their performance in a modeling and simulation challenge. Our qualitative analysis focused on verbal descriptions via a retrospective semi-structured interview and artifacts created by seventeen students after engaging in synthetic modeling activity. The resulting analysis reports overall quality for the types of domain and meta-representational knowledge that students used along with reasoning processes during synthetic modeling activity. The analysis also compared and contrasted the patterns of conceptual understanding and problem-solving skills between three groups, which differed in terms of modeling performance.