Miracle-dz/UniFAR-FTUs huggingface dataset:
Recognition and treatment of depression and anxiety symptoms in heart failure.

OBJECTIVE The aim of this prospective study was to examine the prevalence, recognition, and treatment of depression and anxiety in ambulatory patients with heart failure. METHOD A total of 158 heart failure participants were enrolled between November 2006 and April 2007. Each patient completed a telephone screening interview that included an assessment of heart-failure severity (New York Heart Assciation criteria) as well as measures for depression (Geriatric Depression Scale [GDS]) and anxiety (Geriatric Anxiety Inventory [GAI]). Following study recruitment, each patient's electronic medical record was comprehensively reviewed for the 12 months prestudy and 6 months poststudy assessments to determine whether patients had been recognized as having and/or treated for depression or anxiety. RESULTS Prevalence of depression (GDS score ≥ 6) was 41.8%, and prevalence of anxiety (GAI score ≥ 9) was 25.3%. Of patients with a positive GDS or GAI result, 57.5% had a diagnosis or medical-record notation for depression and/or anxiety, and 60.3% received mental health treatment during the 18-month period of the EMR review. Of patients with a documented diagnosis of depression or anxiety, 92.3% received mental health treatment. Results showed that higher GDS scores were associated with recognition of depression/anxiety in the medical record, and a positive primary care depression screening predicted documented mental health treatment. CONCLUSION These data suggest that symptomatic depression and anxiety are underrecognized in heart failure patients and that mental health screening may be important for receipt of care. Notably, once depression and/or anxiety was documented in the medical record, patients were highly likely to receive mental health treatment.
TWITTIRÒ: a Social Media Corpus with a Multi-layered Annotation for Irony

English. In this paper we describe our work concerning the application of a multi-layered scheme for the fine-grained annotation of irony (Karoui et al., 2017) on a new Italian social media corpus. In applying the annotation on this corpus containing tweets, i.e. TWITTIRÒ, we outlined both strengths and weaknesses of the scheme when applied on Italian, thus giving further clarity on the future directions that can be followed in the multilingual and cross-language perspective. Italiano. In questo articolo descriviamo la creazione di un corpus di testi estratti da social media in italiano e l’applicazione ad esso di uno schema multilivello per l’annotazione a grana fine dell’ironia sviluppato in (Karoui et al., 2017). Nell’applicare l’annotazione a questo corpus composto da messaggi di Twitter, i.e. TWITTIRÒ, abbiamo discusso i punti di forza ed i limiti dello schema stesso, in modo da evidenziare le direzioni da seguire in futuro anche in prospettiva multilingue e cross linguistica.
Outer Segment Thickness Predicts Visual Field Response to QLT091001 in Patients with RPE65 or LRAT Mutations.

PURPOSE To determine whether the degree of change in Goldmann visual fields (GVFs) following oral administration of QLT091001 was related to baseline measures of retinal structure. METHODS Oral QLT091001 was administered once daily for 7 days in all study patients. Comprehensive ophthalmic testing, including spectral-domain optical coherence tomography (SD-OCT), was conducted in 14 patients with Leber congenital amaurosis (LCA) and 18 patients with retinitis pigmentosa (RP) at seven international sites. Average thickness of the outer segment (OS) layer was calculated over central 20°. Both eyes of each subject were evaluated separately. RESULTS Nineteen of 28 eyes (68%) with LCA and 13 of 36 eyes (36%) with RP responded to QLT091001. Among these responders, the average baseline thickness of the OS layer (central 20°) was 13.5 μm in the LCA cohort and 11.7 μm in the RP cohort. Nonresponders had average baseline OS thickness of less than 4.6 μm in both cohorts. The OS thickness in the central 20° was significantly shorter in nonresponders than responders in the LCA cohort (P = 0.01, t-test) and in the RP cohort (P = 0.02, Wilcoxon rank sum test). The OS thickness in the central 20° did not change significantly from baseline during the first 2 months (P = 0.09, t-test, paired). CONCLUSIONS The present findings suggest that there is a close parallel between the thickness of the photoreceptor layer and the potential for functional improvement in these patients. TRANSLATIONAL RELEVANCE SD-OCT thickness in the central retina may be useful for predicting the visual field response in the peripheral retina to QLT091001. (https://clinicaltrials.gov/ct2/show/NCT01014052 number, NCT01014052).
CD4-Dependent and CD4-independent utilization of coreceptors by human immunodeficiency viruses type 2 and simian immunodeficiency viruses.

More than 10 G protein-coupled receptors (GPCRs) have been reported to act as coreceptors for entry of human and simian immunodeficiency viruses (HIV and SIV). We investigated the utilization of six GPCRs as coreceptors by T-cell-line-adapted HIV-2 strains (CBL-20, CBL-21, CBL-23, GH-1, ROD, and SBL6669) and SIV strains (SIVagmTYO-1, SIVmac251, and SIVmndGB-1). NP-2/CD4 cells were transduced with CCR3, CCR5, CCR8, CXCR4, GPR1, or APJ, and examined for susceptibilities to cell-free HIV/SIV. HIV-2 strains were grouped into two types by their coreceptor usage. The first group, CBL-20 and CBL-21, used CXCR4 exclusively; the other four strains used a few or all of the six coreceptors. These strains could further infect CD4-negative NP-2/CXCR4 or NP-2/CCR5 cells in the presence (all strains) or absence (SBL6669 and ROD strains) of soluble CD4. SIVagm and SIVmnd infected NP-2/CD4/GPR1 cells. The coreceptors CCR3, CCR8, GPR1, and APJ did not mediate the CD4-independent infection. Although HIV-2ROD and SIVmnd infected both NP-2/CD4/CXCR4 and NP-2/CD4/CCR5 cells, only CXCR4 and CCR5, respectively, were used in CD4-independent infection. Binding of virions to CD4-negative cells occurred at 4 degrees C. These findings suggest that there may be a correlation between the promiscuous use of coreceptors by HIV-2/SIV strains and their ability to infect CD4-negative cells.
Design Tools for an Emerging SoC Technology: Quantum-Dot Cellular Automata

The future of system-on-chip (SoC) technologies, based on the scaling of current FET-based integrated circuitry, is being predicted to reach fabrication limits by the year 2015. Economic limits may be reached before that time. Continued scaling of electronic devices to molecular scales will undoubtedly require a paradigm shift from the FET-based switch to an alternative mechanism of information representation and processing. This paradigm shift will also have to encompass the tools and design culture that have made the current SoC technology possible-the ability to design monolithic integrated circuits with many hundreds of millions of transistors. In this paper, we examine the initial development of a tool to automate the design of one of the promising emerging nanoelectronic technologies, quantum-dot cellular automata, which has been proposed as a computing paradigm based on single electron effects within quantum dots and molecules.
PI sliding mode control for the non-linear system

This article presents one approach to adaptation control sliding mode led to a PI controller (PISMC) for controlling an induction motor in an electric vehicle application. The PISMC has the advantage to be robust, efficient, and eliminates the phenomenon of "chattering. " The controller performance is demonstrated via result of simulation in which the proposed controller effectiveness is compared to conventional SMC.
Contract competition between hierarchies, managerial compensation and imperfectly correlated shocks

We analyze competition through incentive contracts for managers in duopoly. Privately informed managers exert surplus enhancing effort that generates an externality on the rival. Asymmetric information on imperfectly correlated shocks creates a two-way distortion of efforts under strategic substitutability in effort and a double downward distortion under strategic complementarity in effort. In the first case, as with contracts for R&D activity or small contractual spillovers for quantity and price competition, increasing the correlation of types reduces the polarization of contracts and the differentials in managerial compensations between efficient and inefficient managers. In the second case, as with large contractual spillovers, the opposite occurs.
Crisis in the community.

From the combination of knowledge and actions, someone can improve their skill and ability. It will lead them to live and work much better. This is why, the students, workers, or even employers should have reading habit for books. Any book will give certain knowledge to take all benefits. This is what this crisis in the community tells you. It will add more knowledge of you to life and work better. Try it and prove it.
Automated nucleic biosensors - a key to high resolution monitoring of marine phytoplankton

Changes in plankton community structures in response to climate change and the climatic sensitivity of species are currently driving topics in marine research. In the marine environment phytoplankton consists of major primary producers, but also harmful algae that can negatively influence marine ecosystems. It is expected that climate related environmental change could result in changes in the abundance, spatial distribution, biogeography or dominance of phytoplankton species. In order to evaluate consequences of climate change for marine ecosystems it is necessary to possess high resolution information in time and space on current abundances and patterns within the phytoplankton. However, the generation of these data is constrained by a variety of reasons like the size or insufficient morphological markers of the taxa and the costs to provide samples with high spatiotemporal resolution. In the past decade the application of biosensor technology has gained significant impact in respect to microbial analysis. More and more publications describe the development of molecular sensors dedicated to the detection of microbial organisms. In the EU FP6- project ALGADEC a portable semi-automated biosensor-system has been developed in order to facilitate the detection of toxic algae in the field. This device enables the electrochemical detection of microalgae from watersamples in less than two hours, without the need of expensive equipment. This device is a prototype device that serves as a cornerstone of a new molecular based strategy for the monitoring of phytoplankton. Currently we are working on the adaptation of the biosensor to the surveillance of key species in the North Sea. And, we aim at a full automation of the system in order to provide an autonomous monitoring tool for phytoplankton. In the Future an autonomous biosensor can be combined with present in situ measurement systems for the marine environment like the FerryBox-system of the GKSS. This would serve the need for technologies that allow high resolution monitoring of marine phytoplankton in order to evaluate consequences of environmental change in the oceans.
Esthetic treatment of gingival melanin hyperpigmentation with Er:YAG laser: short-term clinical observations and patient follow-up.

BACKGROUND Recently, the erbium-doped:yttrium, aluminum, and garnet (Er:YAG) laser has been applied effectively for periodontal soft tissue management. The purpose of this study was to report removal of gingival melanin pigmentation using an Er:YAG laser in a short-term clinical observation. METHODS Five patients with gingival melanin pigmentation participated in this study. Irradiation was performed at 64.0 mJ/pulse (8.5 J/cm2 per pulse) and 10 Hz under water spray in contact mode. Clinical parameters, such as bleeding, swelling, redness, and healing, were evaluated immediately after the surgery and 24 hours, 1 and 4 weeks, and 3 months later. A visual analog scale was used to evaluate the pain level experienced. RESULTS The Er:YAG laser effectively ablated the epithelial tissue containing melanin pigmentation. At 1 week, gingiva showed fast epithelization with a healthy appearance in all cases. At 2 weeks, gingiva showed satisfactory healing with significant improvement in color and recovery of the tissue thickness. At 1 month, complete healing was observed; after the 3-month evaluation, no gingival deformity or recession was observed. However, there was a slight recurrence in one case. CONCLUSION Removal of gingival melanin pigmentation can be performed safely by Er:YAG laser resulting in an esthetically significant improvement of gingival discoloration.
Don't Worry About it: Managing Variability On-The-Fly

Software-product-line engineering (SPLE) has become a widely adopted concept to implement reusable source code. However, instead of using SPLE from the beginning (the proactive approach), a software product line (SPL) is often only introduced after a set of similar systems is already developed (the extractive approach). This can lead to additional costs, new bugs introduced by refactoring, and an overall inconsistent SPL. In particular, inconsistencies between the variability implemented in the source code and the one represented in a variability model can become a major problem. To address this issue, we propose the concept of variability management derivation: We aim to (semi-)automatically model features and their dependencies while developers implement variable source code to facilitate the initial development, reusability, and later maintainability of SPLs, utilizing the reactive approach. In this paper, we demonstrate our concept by means of preprocessors. However, we claim that it can be adapted for other SPLE implementation techniques to facilitate SPL development.
Ensemble methods for sentiment analysis of on-line micro-texts

Now a days, the Twitter has become a most trusted platform of on-line micro-texts (tweets) for monitoring the public sentiment for any entity (events, topic or products). In recent years, many approaches have been used for sentiment analysis of on-line micro-texts in a manner to predict the public opinion for real world entities. However, the accuracy of prediction is highly dependent on the accuracy of the sentiment analysis. The consistent performance of the multiple classifiers (ensembles) approaches in many applications of classification promotes the use of an ensemble of classifiers for sentiment analysis of on-line micro-texts too. Therefore, while considering the sentiment analysis of on-line micro-texts as a task of classification in machine learning, this paper investigates for the sovereignty of ensemble methods over other methods for the task and discusses the various setting of ensembles for the sentiment analysis of on-line micro-texts.
Reliability of a single objective measure in assessing sleepiness.

STUDY OBJECTIVES To evaluate reliability of single objective tests in assessing sleepiness. DESIGN Subjects who completed polysomnography underwent a 4-nap multiple sleep latency test (MSLT) the following day. Prior to each nap opportunity on MSLT, subjects performed the psychomotor vigilance test (PVT) and divided attention driving task (DADT). Results of single versus multiple test administrations were compared using the intraclass correlation coefficient (ICC) and adjusted for test administration order effects to explore time of day effects. Measures were explored as continuous and binary (i.e., impaired or not impaired). SETTING Community-based sample evaluated at a tertiary, university-based sleep center. PARTICIPANTS 372 adult commercial vehicle operators oversampled for increased obstructive sleep apnea risk. INTERVENTIONS N/A. MEASUREMENTS AND RESULTS AS CONTINUOUS MEASURES, ICC WERE AS FOLLOWS: MSLT 0.45, PVT median response time 0.69, PVT number of lapses 0.51, 10-min DADT tracking error 0.87, 20-min DADT tracking error 0.90. Based on binary outcomes, ICC were: MSLT 0.63, PVT number of lapses 0.85, 10-min DADT 0.95, 20-min DADT 0.96. Statistically significant time of day effects were seen in both the MSLT and PVT but not the DADT. Correlation between ESS and different objective tests was strongest for MSLT, range [-0.270 to -0.195] and persisted across all time points. CONCLUSIONS Single DADT and PVT administrations are reliable measures of sleepiness. A single MSLT administration can reasonably discriminate individuals with MSL < 8 minutes. These results support the use of a single administration of some objective tests of sleepiness when performed under controlled conditions in routine clinical care.
A broadband U-slot loaded circular disk patch antenna

A broadband antenna is achieved by introducing U-shaped of slot in circular disk patch. In U- slot loaded disk antenna, typically 24.21 % bandwidth is obtained. Variation of slot length (Ls), slot width (T), and base length ( Lb) are studied to obtain the desired bandwidth and good matching. The theoretical results compare well with IE3D simulation and experimental results.
Kinetic Behavior in Altered Clinical States: Approach to Objective Analysis of Motor Behavior during Clinical Interviews

This paper presents a scheme, derived both rationally and empirically, for the analysis of body movements occurring spontaneously in psychotherapeutic interviews. Focussing on hand movements, a distinction is made between two broad, conceptually different, and independent classes of movements: those accompanying speech (object-focussed), and those involving some form of self-stimulation but not speech-related (body-focussed). Furthermore, different kinds of object-focussed movements are identified according to their integration with and primacy vis-a-vis speech. Observations on two paranoid patients, each at two different points in his treatment, suggest that the coding scheme can reflect the patient's altered clinical states.
Microbiological and chemical changes in freshwater prawn (Macrobrachium rosembergii) stored under refrigeration

Microbiological and chemical changes were evaluated in freshwater prawn stored under refrigeration at 0°C and 5°C during 10 days, with special emphasis on indole production as a chemical spoilage indicator. The total psychrotrophic and indole positive microflora were mainly mesophilic, with indole positive microorganisms being less than 10% of the total microflora after 10 days storage under refrigeration. Bacteria from Enterobacteriaceae and Vibrionaceae families prevailed among the isolated indole positive strains. The use of the Most Probable Number-MPN method, using tryptone broth as culture medium, was the most reliable approach for the quantitative evaluation of the indole positive microflora. The stored samples showed increases in pH, L-tryptophan and total volatile bases (TVB), which were more intensive at 5°C. The psychrotrophic counts and TVB values of samples stored at 0°C were lower than the recommended limits (107 CFU/g and 30 mg N/100g, respectively), even after 10 days storage. However, in samples stored at 5°C, these values were reached after 10 and 5 days, respectively. The presence of indole in levels above the limit recommended by FDA/USA (25 mg/100g) was confirmed in only one sample, suggesting that this substance, alone, wouldnt be a good indicator of freshwater prawn quality stored under refrigeration.
Hepatitis C virus infection and the prevalence of renal insufficiency.

BACKGROUND Hepatitis C virus (HCV) is associated with pathologic changes in the kidney. However, the association between HCV and renal dysfunction is not well defined. DESIGN, SETTING, PARTICIPANTS, AND MEASUREMENTS This study estimated the prevalence of renal insufficiency among veterans who received care through the Veterans Affairs Puget Sound Health Care System. The study population consisted of veterans who underwent HCV antibody testing between January 1, 1999, and December 31, 2004, and had at least one primary care or medical subspecialty visit and at least one outpatient creatinine measurement within the 18 mo before antibody testing. Veterans were excluded when they had a history of chronic dialysis, creatinine >5 mg/dl, or renal transplantation. Study data were extracted from the electronic medical record. Renal insufficiency was defined as a creatinine level > or =1.5 mg/dl. Multivariate logistic regression was performed to estimate the risk for renal insufficiency associated with HCV. Among 25,782 eligible veterans, 1928 were HCV antibody positive and 23,854 were HCV antibody negative. RESULTS Although the proportion with renal insufficiency was lower for antibody-positive versus -negative veterans (4.8 versus 6.0%), after adjustment for age, race, gender, diabetes, and hypertension, HCV-positive veterans had a 40% higher odds for renal insufficiency (odds ratio 1.40; 95% confidence interval 1.11 to 1.76) as compared with HCV-negative veterans. CONCLUSIONS HCV was associated with an increased prevalence of renal insufficiency.
Long-range and short-range surface plasmon resonance in coupled plasmonic structure using bimetallic nanofilms

Long-range and short-range surface plasmon resonance has been discussed for mono and bi-metallic coupled plasmonic structures. Reflectivity and field enhancement plots with simultaneous angular and wavelength interrogation along with the two dimensional (2D) contour plots provide significant information about the resonance phenomena in these two cases. Moreover, substrate and sample dependency help to choose the correct layer parameters for designing a nanoplasmonic sensor.
Errorless (re)learning of everyday activities in patients with Korsakoff’s syndrome: A feasibility study

ABSTRACT Errorless learning has proven to be an effective method for (re)learning tasks in several patient groups with amnesia. However, so far only a handful of studies have examined the effects of errorless learning in patients with Korsakoff’s syndrome. The aims of this feasibility study were to (a) examine the effects of errorless learning training on (re)learning tasks in a patient with Korsakoff’s syndrome, (b) examine the effects of the nature of the training on the execution of the tasks, and (c) examine characteristics that may mediate learning outcome. Professional caregivers, who were trained in errorless learning principles, taught 51 patients with Korsakoff’s syndrome two everyday tasks. Significant improvements in the performance were found after an errorless intervention for different types of trained tasks (activities of daily living, chores, mobility, housekeeping). Moreover, the results of this study suggest that all patients, despite of age, educational level, or level of cognitive functioning, may benefit from errorless learning. The results showed that, despite severe amnesia, patients with Korsakoff’s syndrome have the potential to (re)learn everyday skills. Errorless learning might be beneficial for memory rehabilitation in patients with Korsakoff’s syndrome in clinical practice. The results of this study are clinically relevant, as successfully learning tasks using errorless learning principles might improve autonomy and independence in the daily lives of patients with Korsakoff’s syndrome.