Miracle-dz/UniFAR-FTUs huggingface dataset:
Teachers’ perspectives of giftedness among students who are deaf or hard of hearing

This qualitative, exploratory study describes and interprets the perspectives of giftedness of twelve teachers who work with Deaf and hard of hearing students in a variety of educational settings across Canada. Using in-depth interviews, the resulting twenty-five hours of audio tapes were transcribed and analyzed line by line using procedures suggested by Giorgi and Marton. The supporting literature came from four major areas: (a) the construct of giftedness; (b) giftedness among the disabled population; (c) giftedness among the Deaf and hard of hearing population; and (d) theory related to teachers' knowledge and perspectives. Analysis of the data resulted in presentation of the findings from two perspectives: teachers' understandings of the meanings of giftedness and the process through which these teachers appeared to have gained their knowledge. Teachers' practical knowledge was portrayed in detailed stories of forty-three hard of hearing or Deaf students whom they believed to be gifted and in the way they described the students' achieving, learning and behaving in classroom interactions. The teachers' conceptually oriented knowledge was described as they reflected upon the meanings they associated with giftedness. The teachers' knowledge of giftedness was compared to that found in the gifted literature at both the practical and theoretical levels. Through interpretations derived from daily interactions with students and drawing on knowledge gained from personal experience, these teachers constructed perspectives of giftedness. The process that emerged illustrated the teachers' use of comparison groups as ways of gaining insight about the students and teachers' ideas about the use of labeling. The teachers' perspectives suggest that Deaf and hard of hearing students are gifted in ways similar but not identical to hearing students. The abilities of these students appear to be different from others in the "handicapped-gifted" literature and their needs are unique. The teachers' more conceptually oriented ideas also appeared to be similar but not identical to theoretical definitions of giftedness.
The guanine nucleotide exchange factor RasGRF1 directly binds microtubules via DHPH2‐mediated interaction

RasGRF is a family of guanine nucleotide exchange factors with dual specificity for both Ras and Rac GTPases. In this study, using mouse brain extracts, we show that both RasGRF1 and RasGRF2 interact with microtubules in an in vitro microtubule assembly system and this binding is very tight. To characterize this association, recombinant purified proteins containing different regions of RasGRF1 were tested for their ability to bind microtubules preassembled from pure tubulin. Only the DHPH2 tandem directly associates with microtubules, whereas the isolated DH or PH2 domains do not, indicating that the entire DHPH2 region is required for this association. The interaction occurs with high affinity (Kd≈ 2 µm) and with a stoichiometry, at saturating conditions, of one DHPH2 molecule for two tubulin dimers. Competition experiments support the hypothesis that the DHPH2 module is largely responsible for RasGRF1–microtubule interaction. In vivo colocalization of RasGRF1 and microtubules was also observed by fluorescence confocal microscopy in nonneuronal cells after stimulation with an oxidative stress agent and in highly differentiated neuron‐like cells. Identification of microtubules as new binding partners of RasGRF1 may help to elucidate the signaling network in which RasGRF1 is involved.
Young women's perspectives on public health knowledge and adolescent bodies

This study examines health information about adolescent bodies from the perspective of young middle-class women, with the aim of determining ways in which health and education professionals could better serve young women. This qualitative study comprised ``memory work'' with eight Finnish women students. The findings suggest that young women prefer the information on menstruation that is given by public health professionals, because of its impersonal form, rather than personal encounters with relatives and peers. The information provided by public health professionals does not, however, meet the women's needs. This discrepancy can be explained by the gap between the narrow medical discourse on women's bodies held by the professionals and the experiences of young women. It is argued that public health representatives need to accommodate their knowledge to the everyday life interests and needs of adolescent women.
Security analysis of the RBS block cipher

Radio Frequency Identification (RFID) systems are widely used today because of their low price, usability and being wireless. As RFID systems use wireless communication, they may encounter challenging security problems. Several lightweight encryption algorithms have been proposed so far to solve these problems. The RBS block cipher is one of these algorithms. In designing RBS, conventional block cipher elements such as S-box and P-box are not used. RBS is based on inserting redundant bits between altered plaintext bits using an encryption key Kenc. In this paper, considering not having a proper diffusion as the main defect of RBS, we propose a chosen ciphertext attack against this algorithm. The data complexity of this attack equals to N pairs of text and its time complexity equals to N decryptions, where N is the size of the encryption key Kenc.
Omega‐3 fatty acid biomarkers and subsequent depressive symptoms

We sought to determine the relationship between the omega‐3 fatty acid content of red blood cell membranes (RBC), in particular docosahexaenoic acid (DHA) and eicosapentaenoic acid (EPA), and baseline and new‐onset depressive symptoms in post‐menopausal women. We secondarily sought to characterize the association between dietary omega‐3 fatty acid intake and depressive symptomatology.
metilene: fast and sensitive calling of differentially methylated regions from bisulfite sequencing data

The detection of differentially methylated regions (DMRs) is a necessary prerequisite for characterizing different epigenetic states. We present a novel program, metilene, to identify DMRs within whole-genome and targeted data with unrivaled specificity and sensitivity. A binary segmentation algorithm combined with a two-dimensional statistical test allows the detection of DMRs in large methylation experiments with multiple groups of samples in minutes rather than days using off-the-shelf hardware. metilene outperforms other state-of-the-art tools for low coverage data and can estimate missing data. Hence, metilene is a versatile tool to study the effect of epigenetic modifications in differentiation/development, tumorigenesis, and systems biology on a global, genome-wide level. Whether in the framework of international consortia with dozens of samples per group, or even without biological replicates, it produces highly significant and reliable results.
Determinants and effects of vitamin D supplementation on serum 25-hydroxy-vitamin D levels in patients with rheumatoid arthritis.

OBJECTIVES Osteoporosis (OP) and increased risk of fracture are relevant features in patients with rheumatoid arthritis (RA). Low levels of serum vitamin D are frequently reported and correlate with a higher RA activity. This study evaluated factors related with the prescription of vitamin D supplements in RA patients and variables influencing the achievement of adequate vitamin D levels. METHODS Study population was made up by 1168 consecutive RA patients from 22 Italian rheumatology centers. Demographic and clinical variables data were collected and 25OH serum vitamin D was measured in all patients. Insufficient serum 25OH vitamin D levels were defined as values lower than 20 ng/mL. RESULTS The majority of patients (56.0%) was not taking vitamin D supplements. Among the 514 supplemented patients, 196 (38.1%) were taking insufficient dosages (≤440 IU/day). Variables related with the prescription of supplements were older age, female sex, previous bone density assessment and OP diagnosis. Among the 318 patients using daily supplements ≥800 IU, 88 patients (27.7%) did not reach adequate levels of vitamin D. In these patients a higher HAQ score (OR for 1 point=1.62, 95% CI: 1.06-2.49; p=0.03) and poor sun exposure (OR=2.38, 95% CI: 1.05-5.55; p=0.04) were predictors of vitamin D insufficiency. CONCLUSIONS Vitamin D deficiency is common in patients with RA, even in patients who are regularly using supplements. Vitamin D supplementation is often ineffective even at the recommended dose of 800 IU/day in more disabled patients.
Restorable VPN Transmission System for Images Broadcasting System

The previous work, suggests a portioned picturebroadcasting system where screens of small size are accumulated togenerate screen of bigger size through Ethernet network interfacethat helps in easy install & implementation of digitized displaydevices. The system makes use of Texas Instruments Da Vinciplatform, that is comprised of Da Vinci TMS320DM6646 dual coreCPU along an ARM9 core & C64+ digitized signal processor as abasic preprocessor & accelerated processor to enhance the speed ofpartitioning the picture & transmission in the several devices fordisplay. A protocol having low value for overhead is taken intoaccount for synchronizing each frame in distributed multimediasystem in the connection. For dealing such issues of delay in nettransmission & loss of packets, a standard precision time protocolIEEE 1588 is applied & transformed to attain seamless partitionedsystem of broadcasting. In this paper, an algorithm is suggestedthat search for backup path for a provided VPN (VPN tree) thatfalls under single link failure model. As any failure of link in a VPNtree is recognized, a backup path associated to the failing link istriggered for restoring the de-linked VPN tree to another one &further ensure reliability of a provided VPN. The proposedalgorithm has the ability for minimizing the delay in transmission & loss of packets.
Reasoning about ceteris paribus preference with constraint hierarchy framework

CP-networks provide a convenient means for expressing preferences in reasoning, but it is not good at handling preferences with hard constraints. The paper proposes a new approach, which transforms the CP-network with hard constraints into one constraint hierarchy, therefore one could process preferences and constraints in a single formalism with fruitful constraint solving algorithms. Furthermore, illustrates it with some examples, proves that the transformation preserves the ceteris paribus property and presents some complexity results. Finally compares it with related work and concludes the paper.
Ribosomal Protein S5e is Implicated in Translation Initiation through its Interaction with the N‐Terminal Domain of Initiation Factor eIF2α

A key step of translation initiation in eukaryotes is formation of the 48S preinitiation complex (PIC) containing the 40S ribosome, a set of eukaryotic initiation factors (eIFs), mRNA, and initiator Met‐tRNA interacting with mRNA start codon; however, the PIC structure remains substantially unknown. Here, we apply formaldehyde‐induced protein–protein crosslinks to identify contacts between ribosomal protein S5e (rpS5e, “e” stands for “eukaryotic”) and eIFs within the mammalian PIC, assembled on either model canonical or IRES‐containing mRNA. Using immunoblotting and mass spectrometry, we show that with both types of mRNA, rpS5e crosslinks to eIF2α. Comparative analysis of peptides resulting from trypsinolysis of the crosslinked proteins before and after crosslink reversal reveals crosslinked peptides in the N‐terminal parts of rpS5e and eIF2α. Application of these data to a model PIC structure obtained with the use of available structures indicates that eIF2α undergoes major conformation rearrangements to enable contacts of the factor with rpS5e. These contacts are suggested to maintain the correct positioning of eIF2α relative to other PIC components; this could be essential for start‐codon selection by the PIC.
Cerebellar Degeneration

Five patients developed cerebellar degenerat ion while being treated w i t h phenytoin. All had h i g h plasma levels of the drug , and none was having seizures of a type that could have caused systemic hypoxia at the t ime the cerebellar syndrome appeared. Cerebellar degeneration was confirmed by the finding of a t rophy on CT scan and by persistence of cerebellar signs w h e n plasma phenytoin levels were decreased. We suggest that chronic phenytoin therapy can cause cerebellar degeneration. T h e question of whether phenytoin or the cumulative effect o f hypoxia f rom repeated convulsions causes cerebellar degeneration should not be posed as one of exclusive alternatives, since hypoxia is a well-known cause of cerebellar atrophy. Instead, the question should be whether or not phenytoin can also be responsible. The cases reported here suggest that i t can.
Improving particle swarm optimization: Using neighbor heuristic and Gaussian cloud learning

The Particle Swarm Optimization (PSO) is a heuristic optimization technique-based swarm intelligence that can be applied to solving many real-world optimization problems. However, the standard PSO algorithm can easily get trapped in the local optima and has slow convergence speed, and these drawbacks have hindered its further development in all fields. In this paper, a new optimization method based on neighbor heuristic and Gaussian cloud learning is introduced in order to improve the performance of traditional PSO (NHPSO). The NHPSO consists of two main steps. First, by analyzing the relationship among particles in the evolutionary process, a neighbor heuristic mechanism is performed to improve the search efficiency and convergence speed. In addition, a Gaussian cloud learning strategy is introduced to enhance population diversity and balance the global and local search abilities. The performance of the NHPSO is tested using 12 benchmark functions and 6 shifted functions. Results show that NHPSO is superior to the recent variants of PSO in terms of convergence speed, solution accuracy, algorithm efficiency and robustness.
Altered brain activation during response inhibition in children with primary nocturnal enuresis: An fMRI study

Nocturnal enuresis is a common developmental disorder in children, and primary nocturnal enuresis (PNE) is the dominant subtype. The main purpose of this study was to investigate brain functional abnormalities specifically related to motor response inhibition in children with PNE using fMRI in combination with a Go/NoGo task. Twenty‐two children with PNE and 22 healthy children, group‐matched for age and sex, took part in this experiment. Although no significant between‐group differences in task performance accuracy were observed, PNE patients showed significantly longer response times on average. There were several brain regions with reduced activation during motor response inhibition in children with PNE: the bilateral inferior frontal gyri, right superior and middle frontal gyri, right inferior parietal lobe, bilateral cingulate gyri and insula. Our data indicate that response inhibition in children with PNE is associated with a relative lack of or delay in the maturation of prefrontal cortex circuitry that is known to suppress inappropriate responses. This result might give clues to understanding the pathophysiology of PNE. Hum Brain Mapp, 2012. © 2011 Wiley Periodicals, Inc.
Modulo scheduler implementation for VLIW processor

For VLIW processors, compiler must statically schedule instructions since there are no hardware for detecting hazards and reordering instructions at runtime. Thus, instruction scheduling techniques for VLIW processors have critical influence on correct execution and effective utilization of hardware resources. Software pipelining is a popular instruction scheduling technique which enables overlapped execution of successive loop iterations. We implemented modulo scheduler, which is a widely used technique of obtaining software pipelined schedule. Experiments on a set of multimedia applications show that performance is increased up to 2.6x compared to simple list scheduling implementation.
Special Issue: What is Concurrent Engineering?

Concurrent engineering (CE) is fundamentally about producing better manufactured things. Initially, most research and implementation concentrated on improving communications within design teams. Research has become more diffuse, and definitions for CE abound. This issue does not attempt to provide a single or unifying definition. Indeed, the whole notion of CE has so imbedded itself in the psyche of both academia and industry that defining it becomes as difficult as defining manufacturing itself. Instead, we have chosen to collect a series of research articles on new directions in CE research that articulate part of a broader vision of what CE is and where it should head, and short essays on the state of CE and how these papers relate to it. As observed by Tetsuo Tomiyama in the first paper of this issue (which constitutes a second and more eloquent introduction), concurrent engineering can be seen historically as an American attempt to understand, implement, and surpass the best Japanese product-development practices. Alternatively, CE can be seen conceptually as an effort to integrate all aspects of design, marketing, finance, and production, by performing simultaneously many activities that used to be done sequentially. In either view, the goal is improved quality, reduced time-to-market, better financial structures (including improved procurement), and a host of other improvements. Most concurrent engineering efforts focus in one way or another on improving communication. Examples of these efforts include collocating (both physically and electronically) and dedicating development teams; appointing strong, integrating project managers; and constructing procedures, such as Quality Function Deployment, to facilitate joint work among different parts of the team. These efforts have achieved major successes, and encour-
Dynamic High-Pass Filtered Subgrid-Scale Models for LES

A ferrule for use as a medical device which maker mechanical connection with external connector tubes provided; the ferrule comprises an inner wall defining a conduit extending between an inlet opening and an outlet opening; a first taper lock surface is defined by a first region of the inner wall for forming a taper lock with a first connector portion having first dimensions; and a second taper lock surface is defined by a second region of the inner wall for forming a taper lock with a second connector portion having second dimensions.
Fault-Tolerant Control Using the GA Optimization Considering the Reluctance Torque of a Five-Phase Flux Switching Machine

This paper deals with the fault tolerance of a five-phase flux switching machine. Short-circuit currents calculation considering inductances variation is developed. Machine behavior (torque quality, copper losses, and homopolar current) under a single short-circuit phase fault, two consecutive and nonconsecutive phases short-circuited, is simulated with a two-dimensional finite elements (2-D FE) model and validated experimentally. Then, a new method is developed to improve its performances in faulty mode, by reconfiguring reference currents. In fact, an accurate torque model is established and then used in a genetic algorithm to optimize reference currents in faulty mode. In this approach of reference currents computation, the used algorithm has multiobjectives and multiconstraints, thereby allowing choosing the appropriate fault-tolerant current solution according to our application. The torque model is considered to be more accurate and closer to the 2-D FE results in both healthy and faulty modes. Then, a comparison of machine performances in healthy, degraded, and reconfigured modes is presented. Experimental results corroborate the analysis.
Condition monitoring and diagnosis of ultrahigh-speed cigarette carton packaging machine based on operational mode recognition

Due to the multi-mode characteristic of cigarette carton packaging machine, the traditional monitoring method such as data report and manual observation can not meet the need of high-efficient cigarette production. Based on operational mode recognition, a condition monitoring and diagnosis approach of ultrahigh-speed cigarette carton packaging machine was proposed. The stability factor within a sliding time window and adaptive k-means clustering method was used to partition the operational space and form several steady mode sub-spaces, fully considering the multi-mode characteristic of operation process. The statistical monitoring model was established by utilizing principal component analysis (PCA) for each steady mode sub-space. The mode recognition of online data was realized by using stability factor within the current sliding time window. In steady mode, the matching monitoring model was obtained based on the similarity between the current valid data and each cluster center, then the monitoring statistics of online data was calculated based on the matching monitoring model. When any monitoring statistic exceeds the control limit, the fault cause variable was separated by using contribution plot. At last, the efficacy of the proposed method was illustrated by applying it to ultrahigh-speed cigarette carton packaging machine. Testing result showed that, the proposed method can more timely and effectively detect fault and separate fault cause variable.
On An Interpretation Of Spectral Clustering Via Heat Equation And Finite Elements Theory

Spectral clustering methods use eigenvectors of a matrix, called Gaussian affinity matrix, in order to define a low-dimensional space in which data points can be clustered. This matrix is widely used and depends on a free parameter σ. It is usually interpreted as some discretization of the Heat Equation Green kernel. Combining tools from Partial Differential Equations and Finite Elements theory, we propose an interpretation of this spectral method which offers an alternative point of view on how spectral clustering works. This approach develops some particular geometrical properties inherent to eigenfunctions of some specific partial differential equation problem. We analyze experimentally how this geometrical property is recovered in the eigenvectors of the affinity matrix and we also study the influence of the parameter σ.