Miracle-dz/UniFAR-FTUs huggingface dataset:
Long-Term Outcome Up To 40 Years after Single Patch Repair of Complete Atrioventricular Septal Defect in Infancy or Childhood

Objectives Patients with repaired complete atrioventricular septal defect (CAVSD) represent an increasing portion of grown-ups with congenital heart disease. For repair of CAVSD, the single-patch technique has been employed first. This technique requires division of the bridging leaflets, thus, among other issues, long-term function of the atrioventricular valves is of particular concern. Methods Between 1978 and 2001, 100 consecutive patients with isolated CAVSD underwent single-patch repair in our institution. Hospital mortality was 11%. Primary endpoints were clinical status, atrioventricular valve function, and freedom from reoperation in long term. Follow-up was obtained contacting the patient and/or caregiver, and the referring cardiologist. Results Eighty-three patients were eligible for long-term follow-up (21.0 ± 8.7, mean ± standard deviation [21.5; 2.1–40.0, median; min–max] years after surgical repair). Actual long-term mortality was 3.4%. Quality of life (QoL; self- or caregiver-reported in patients with Down syndrome) was excellent or good in 81%, mild congestive heart failure was present in 16%, moderate in 3.6% as estimated by New York Heart Association classification. Echocardiography revealed normal systolic left ventricular function in all cases. Regurgitation of the right atrioventricular valve was mild in 48%, mild–moderate in 3.6%, and moderate in 1.2%. The left atrioventricular valve was mildly stenotic in 15% and mild to moderately stenotic in 2%; regurgitation was mild in 54%, mild to moderate in 13%, and moderate in 15% of patients. Freedom from left atrioventricular-valve-related reoperation was 95.3, 92.7, and 89.3% after 5, 10, and 30 years, respectively. Permanent pacemaker therapy, as an immediate result of CAVSD repair ( n = 7) or as a result of late-onset sick sinus syndrome ( n = 5), required up to six reoperations in single patients. Freedom from pacemaker-related reoperation was 91.4, 84.4, and 51.5% after 5, 10, and 30 years, respectively. Conclusion Up to 40 years after single-patch repair of CAVSD, clinical status and functional results are promising, particularly, in terms of atrioventricular valve function. Permanent pacemaker therapy results in a life-long need for surgical reinterventions.
Design of a Spherical Leak Detector for Submarine Oil Pipelines

Spherical leak detectors can detect very tiny leakage in pipelines and have low risk of blockage. It is very suitable for submarine oil pipelines. In this paper, the passing ability of the detector in the vertical segment of a pipe was studied using CFD simulations. The simulation shows that the drag on the detector by the flow inside the pipe is related to the flow velocity V and the diameter ratio λ (d/D). We found it’s a good choice when λ ranges from 0.7~0.8, and a spherical leak detector (λ=0.8) is designed. The field experimentation shows that the prototype of the detector can go through within normal economical flow velocity (0.7m/s-1.5m/s) in 8 inch pipelines.
Prediction of disease-associated nsSNPs by integrating multi-scale ResNet models with deep feature fusion

More than 6000 human diseases have been recorded to be caused by non-synonymous single nucleotide polymorphisms (nsSNPs). Rapid and accurate prediction of pathogenic nsSNPs can improve our understanding of the principle and design of new drugs, which remains an unresolved challenge. In the present work, a new computational approach, termed MSRes-MutP, is proposed based on ResNet blocks with multi-scale kernel size to predict disease-associated nsSNPs. By feeding the serial concatenation of the extracted four types of features, the performance of MSRes-MutP does not obviously improve. To address this, a second model FFMSRes-MutP is developed, which utilizes deep feature fusion strategy and multi-scale 2D-ResNet and 1D-ResNet blocks to extract relevant two-dimensional features and physicochemical properties. FFMSRes-MutP with the concatenated features achieves a better performance than that with individual features. The performance of FFMSRes-MutP is benchmarked on five different datasets. It achieves the Matthew's correlation coefficient (MCC) of 0.593 and 0.618 on the PredictSNP and MMP datasets, which are 0.101 and 0.210 higher than that of the existing best method PredictSNP1. When tested on the HumDiv and HumVar datasets, it achieves MCC of 0.9605 and 0.9507, and area under curve (AUC) of 0.9796 and 0.9748, which are 0.1747 and 0.2669, 0.0853 and 0.1335, respectively, higher than the existing best methods PolyPhen-2 and FATHMM (weighted). In addition, on blind test using a third-party dataset, FFMSRes-MutP performs as the second-best predictor (with MCC and AUC of 0.5215 and 0.7633, respectively), when compared with the other four predictors. Extensive benchmarking experiments demonstrate that FFMSRes-MutP achieves effective feature fusion and can be explored as a useful approach for predicting disease-associated nsSNPs. The webserver is freely available at http://csbio.njust. edu.cn/bioinf/ffmsresmutp/ for academic use.
A uniform compact model for planar RF/MMIC interconnect, inductors and transformers

A physics-based compact model for on-chip transmission lines, spiral inductors and transformers is presented. This SPICE-compatible model can be distributed to extend its range of validity. It includes all important sources of substrate loss and a simplified capacitance model that speeds parameter extraction. Model accuracy is benchmarked with both experimental measurements and numerical simulations.
India’s Quest for a National Space Law and the Missing Piece of Possessory Rights

As the commercial use of outer space becomes feasible, the nature of possessory rights will potentially emerge as the central focus of future space-related activities. The existing international law relating to outer space does not address in detail the nature of possessory rights in outer space and is subject to multiple interpretations. Alarmingly, the recently adopted space policies and legislations by some States have taken a definitive position regarding the commercial use of natural resources in outer space. In light of India’s increasing involvement in outer space, it circulated the Draft Space Activities Bill, 2017, to formulate a national space law. However, the nature of possessory rights in outer space is not addressed in detail in the Draft Space Activities Bill. This study states that on account of recent developments happening elsewhere, it is extremely important for emerging powers like India to take a position on broader issues like the nature of possessory rights in outer space (which includes celestial bodies as well as resources contained therein). Not addressing the issue of possessory rights in outer space could have profound implications at both domestic as well as international levels.
Quantification of FAM20A in human milk and identification of calcium metabolism proteins

FAM20A, a recently discovered protein, is thought to have a fundamental role in inhibiting ectopic calcification. Several studies have demonstrated that variants of FAM20A are causative for the rare autosomal recessive disorder, enamel‐renal syndrome (ERS). ERS is characterized by defective mineralization of dental enamel and nephrocalcinosis suggesting that FAM20A is an extracellular matrix protein, dysfunction of which causes calcification of the secretory epithelial tissues. FAM20A is a low‐abundant protein that is difficult to detect in biofluids such as blood, saliva, and urine. Thus, we speculated the abundance of FAM20A to be high in human milk, since the secretory epithelium of lactating mammary tissue is involved in the secretion of highly concentrated calcium. Therefore, the primary aim of this research is to describe the processes/methodology taken to quantify FAM20A in human milk and identify other proteins involved in calcium metabolism.
A Pragmatic Approach to Modeling Object Grasp Motion Using Operation and Pressure Signals for Demolition Machines

In this paper, an object grasp motion, which is a requisite condition to make a demolition machine grasp an object, is pragmatically modeled, considering accurate and robust identification. Grasping an object is a highly difficult task that requires safe and precise operations, particularly in disaster response work. Identifying a grasp or non-grasp state is essential for providing operational support. These types of outdoor machines lack visual and tactile sensors, so pragmatically available lever operation and cylinder pressure sensors are adopted as parameters for modeling. The grasp motion is simply defined by using sequential transitions of the on-off state of the operation signal and cylinder pressure data for the grapple and the manipulator. The results of experiments conducted to transport objects using an instrumented hydraulic arm indicated that the modeled grasp motion model effectively identifies a grasp or non-grasp state with high accuracy, independently of operators and work environments.
Rough Sets Based Simplified Analysis of Energy Loss Indicators in Power Plant

There are many kinds of energy loss indicators in power plant, and there are some relevance among the various indicators. So extraction of the key indicators plays an important role between in energy loss analysis of power plants and optimal management of thermal power plants. Based on the characteristics of these indicators, the idea of rough sets was applied to the energy loss analysis of thermal power plants, then we proposed a new algorithm -- use fuzzy C means algorithm (FCM) to discrete cluster the energy loss indicators of thermal power plant, and then analysis simplified the results with algorithm Johnson. Real experiments (Chaozhou 1,2 and Ningde 3,4 assembling units which of the same type in the SIS system under the THA working condition)’ results had proved high accuracy and valuable of the algorithm.
Deprived of Second Derivative Iterated Method for Solving Nonlinear Equations

Non-linear equations are one of the most important and useful problems, which arises in a varied collection of practical applications in engineering and applied sciences. For this purpose, in this paper has been developed an iterative method with deprived of second derivative for the solution of non-linear problems. The developed deprived of second derivative iterative method is convergent quadratically, and which is derived from Newton Raphson Method and Taylor series. The numerical results of the developed method are compared with the Newton Raphson Method and Modified Newton Raphson Method. From graphical representation and numerical results, it has been observed that the deprived of second derivative iterative method is more appropriate and suitable as accuracy and iteration perception by the valuation of Newton Raphson Method and Modified Newton Raphson Method for estimating a non-linear problem.
A web-based open emissions calculator

Many organisations and governmental agencies offer online calculators to calculate the carbon footprint of industrial activities. Furthermore, airline companies offer online tools to estimate carbon footprint and promote the purchase of carbon offsets in order to make the trip carbon neutral. This paper presents a free online emissions calculator that computes various emissions-related statistics for a given ship and operational scenario. This web tool is the first publicly available calculator for the shipping industry.
A comparative characterization of nasal and clinical isolates of Staphylococcus aureus from west of Iran

Background and Objectives: Recently, the rise of methicillin-resistant Staphylococcus aureus (MRSA) isolated from hospital healthcare workers (HCWs) and various infectious samples has become one of the main concerns in hospital settings. Therefore, epidemiological studies are necessary to monitor antibiotic resistance patterns in each region and to study the pathogenesis of this strain to control infections. Materials and Methods: In this cross-sectional study, a total of 100 S. aureus isolates, including 50 isolates obtained from the anterior nares of healthcare workers, as well as 50 other isolates cultured from the various clinical specimens from the referral hospitals in Khorramabad (West of Iran) were tested. All isolates were examined to determine antibiotic resistance pattern, and the presence of staphylococcal enterotoxin A (sea), staphylococcal enterotoxin B (seb) and mecA genes. Results: The mecA gene was found among 36% (18/50) of the clinical S. aureus isolates (CSIs) and 14% (7/50) of nasal S. aureus isolates (NSIs), with statistically significant difference (X2 = 6.53; p = 0.011). The difference between the frequency rate of sea gene among MRSA strains isolated from clinical specimens (46.6%, 7/15) was significant compared to strains isolated from nostrils (14.3%, 1/7) (X2 = 3.85; p = 0.049). Conclusion: The frequency of mecA, sea, and seb genes among the clinical samples was more than strains isolated from the nostrils of healthcare personnel.
Hierarchical Structural Model of AC/DC Power Systems

The hierarchical decomposition and modeling method of large-scale power systems proposed previously is expanded to be suitable for AC/DC power systems in this paper. In the new model of AC/DC systems, DC systems will have the same position as AC systems. The components in AC/DC power systems are classified into three categories, namely conversion components, DC components and AC components. By analyzing the difference between DC interface and AC interface, the unified structural model suitable for any kind of component in AC/DC systems is built. Then, the hierarchical structural model is derived based on the hierarchical decomposition method. The main characteristics of the proposed AC/DC model are the same as that of previous AC model.
Hybrid Electric Vehicle Ownership and Fuel Economy across Texas

Policymakers, transport planners, automobile manufacturers, and others are interested in the factors that affect adoption rates of electric vehicles and other fuel-efficient vehicles. With tract-level data from the 2010 census and registered vehicle counts from Texas counties in 2010, this study investigated the impact of various built environment and demographic attributes, including land use balance, employment density, population density, median age, gender, race, education, household size, and income. Spatial autocorrelation (across census tracts) in unobserved components of vehicle counts by tract and cross-response correlation (both spatial and local–aspatial in nature) was allowed for by the estimation of models of ownership levels (vehicle counts by vehicle type and fuel economy level) with bivariate and trivariate Poisson–lognormal conditional autoregressive models. The presence of high spatial autocorrelations and local cross-response correlations was consistent in all models across all counties studied. Ownership rates for fuel-efficient vehicles were found to rise with household income, resident education levels, and the share of male residents and to fall in the presence of larger household sizes and higher job densities. The average fuel economy of each tract's light-duty vehicles was also analyzed with a spatial error model across all Texas tracts, and this variable was found to depend most on educational attainment levels, median age, income, and household size variables, though all covariates used were statistically significant. If households registering more fuel-efficient vehicles, including hybrid electric vehicles, are also more inclined to purchase plug-in electric vehicles, these findings can assist in spatial planning of charging infrastructure as well as other calculations (such as implications for the revenue from gas tax).
Success of Projects in Different Organizational Conditions

The main purpose of this study is to evaluate the critical success/failure factors in project management and to examine the relationships between critical success factors and organizational background variables. This study also aims to gain an understanding of how project clients, owners, and sponsors present their needs and expectations to ensure project success. On the basis of the survey responses received, it is possible to identify critical success factors in project management that are significantly related to company/organization size, project size, organization type, and project managers’ work experience. The project implementation profile is also analyzed on average and by phases. The results indicate the importance of project communication that is related to company size, however. In contrast to some prior studies, communication was ranked highest in most project phases.
Comparing the Response Burden between Paper and Web Modes in Establishment Surveys

Abstract Previous research is inconclusive regarding the effects of paper and web surveys on response burdens. We conducted an establishment survey with random assignment to paper and web modes to examine this issue. We compare how the actual and perceived response burdens differ when respondents complete a survey in the paper mode, in the web mode and when they are allowed to choose between the two modes. Our results show that in the web mode, respondents have a lower estimated time to complete the questionnaire, while we do not find differences between paper and the web on the perceived response time and perceived burden. Even though the response burden in the web mode is lower, our study finds no evidence of an increased response burden when moving an establishment survey from paper to the web.
Didactics: Peculiarities of Motor Skills Development in Boys Aged 14-15

The purpose of the study was to determine the peculiarities of motor skills development in boys aged 14-15. Materials and methods. The study participants were boys aged 14 (n=20) and 15 (n=20). The children and their parents were fully informed about all the features of the study and gave their consent to participate in the experiment. To solve the tasks set, the following research methods were used: study and analysis of scientific and methodological literature; pedagogical observation, timing of training tasks; pedagogical experiment, methods of mathematical statistics, discriminant analysis, nearest neighbor analysis. Results. The study made an assumption about a significant influence of the modes of alternating exercise repetitions and the rest interval on the effectiveness of motor skills development in boys aged 14 and 15. The standardized canonical discriminant function coefficients helped to determine age peculiarities and the peculiarities of influence of exercise modes on the effectiveness of motor skills development. They showed that the components of motor fitness are a priority in developing motor skills. The structure canonical discriminant function coefficients indicate the importance of movement control skills for mastering the entire exercise. Conclusions. Discriminant analysis revealed the peculiarities of motor skills development in boys aged 14 and 15, depending on age and exercise modes. With the first exercise mode, boys aged 15 master the first, second, and fourth series of training tasks more quickly. Boys aged 14 – the sixth series (exercise mode: 6 repetitions, rest interval of 60 s). With the second exercise mode, boys aged 14 master the first and fourth series of training tasks more quickly. Boys aged 15 – the second series (exercise mode: 12 repetitions, rest interval of 60 s). The coordinates of centroids for four groups indicate a significant difference in the influence of exercise repetition modes on the number of repetitions required for motor skills development in boys aged 14-15 during physical education classes. The results of group classification show that 87.5% of the original grouped cases were classified correctly.
Comprehensive Review of Routing Protocols in Wireless Sensor Networks

Wireless sensor networks (WSNs) are attracting great interest in a number of application domains concerned with monitoring and control of physical phenomena, as they enable dense and boundless deployments at low-cost and with excellent flexibility. Extensive usage of WSN is the reason of development of any routing protocols. The main contribution of this article is an extensive survey and classification of the routing protocols in WSN. Routing protocols are classified under seven categories (Location-Based, Data Centric, Hierarchical-Based, Mobility-Based, Multipath-Based, Heterogeneity based and Quality of Service (QoS)-Based. ). Each protocol is described and discussed with advantage and disadvantages. The challenges faced by WSN are also mentioned in this paper and finally to set the milestone for future work. For researchers, this paper serves as a starting point into research in designing routing protocols for WSNs effectively and efficiently. Any reader who is interested in improving their knowledge of the technical concepts will find a list of references and recent publications at the end of this paper.
Wind‐resistant design of high mast structures

Abstract Today, a large number of High Mast Structures (HMS) is being constructed around the world. Usually, the structural systems are presented as monotubular towers or masts with a mass at the tip which has utility equipment mounted. The monotubular configuration of an HMS has a large ratio of height to horizontal dimension. This means that the HMS is not only very slender, but also more wind‐sensitive than any other common structures. Since failures of masts and monotubular towers or poles have occurred often, this confirms the necessity for a better understanding of wind‐excited behaviour on the HMS, and also a better design for a wind‐resistant HMS. This paper illustrates the basic theories of behaviors of along‐wind response, and across‐wind response. Prior to the present, design codes for HMSes have not been standardized. Therefore, this study has aimed to develop a suitable criterion of Wind Resistant Design (WRD) for HMS. We wish to produce guidelines to be used when designing a wind‐resistant HMS to counter wind‐excited responses. This paper starts with a theoretical approach. Computational Fluid Dynamics (CFD) and Finite Element Method (FEM) are reviewed and applied to the analytical development of the design criteria. Then, the design criteria and the procedure of WRD are established. And finally, a case study is presented for illustration. There are three major findings in this study. First, the results of the analysis of CFD show that when the polygon sides are more than 16, the total drag coefficient tends to the constant, which closes to leeward drag coefficient, and the windward coefficient tends to be zero. Second, it's recommended that an HMS had better adopt a gust effect factor, G, equal to 2.33 due to flexibility by geometric configuration and structural properties. Third, the total maximum response limitation of an HMS should be considered in across‐wind analysis for WRD procedures.
ADAPTIVE BACKSTEPPING SLIDING-MODE CONTROL WITH APPLICATION TO A FLEXIBLE-JOINT MANIPULATOR

Abstract This paper is concerned with the adaptive backstepping sliding-mode control of nonlinear dynamic systems with model uncertainties. The proposed control method suitable for mechatronic systems combines the advantages of sliding-mode control and backstepping methodology, such that the requirement of the matching condition is removed, which seriously clams the application of sliding-mode control. In the control scheme, networks of Gaussian radial basis functions with variable weights are used to compensate the model uncertainties. The adaptive law developed using the Lyapunov synthesis approach guarantees the stability of the control scheme. The performance is illustrated by experimental studies with a flexible-joint manipulator.