Miracle-dz/UniFAR-FTUs huggingface dataset:
Development and validation of a presumptive colour spot test method for the detection of piperazine analogues in seized illicit materials

The increasingly large quantities of potentially illicit samples received for confirmatory analysis highlights the importance and demand for preliminary testing procedures that are simple, rapid, selective, inexpensive and able to be used in the field. Colour testing fulfils the aforementioned requirements and is a technique frequently employed to achieve presumptive identification. Piperazine analogues (often marketed as ‘legal ecstasy’) are a group of psychoactive substances that have recently become established on the illicit drug market and are not effectively discriminated or identified by current colour testing methods. Herein, we report on the development and validation of a chemical spot test for piperazine analogues present in unknown seized materials using the spectrophotometric reagent, sodium 1,2-naphthoquinone-4-sulphonate (NQS). Primary testing revealed that NQS reacts almost instantly to form an intense, bright orange-red coloured complex with the representative piperazine 1-benzylpiperazine (BZP) at room temperature. The results of the test, assessed by colour development, were evaluated visually and variables affecting the coloured reaction were optimised. The colour test method was validated to meet requirements for use in preliminary screening, providing qualitative and reliable presumptive test results. Validation studies show that the characteristic colour change is unique to the piperazine class at room temperature, and is unaffected by the presence of common cutting agents, i.e. glucose and caffeine, in test samples of 5% purity, and other drugs such as N-methyl-3,4-methylenedioxyamphetamine (MDMA). The NQS reagent stability was found to be limited to storage in a refrigerated environment for no more than one week before results were affected. The operational limit of detection was found to be 40 μg.
Development of Stability Indicating RP-HPLC Method for Simultaneous Estimation of Amlodipine and Olmesartan in Pure and Pharmaceutical Dosage Form

A simple reverse phase HPLC method was developed for the simultaneous estimation of Amlodipine and Olmesartan in bulk and tablet form. Chromatography was performed by isocratic reverse phase separation on a stainless steel column 4.6 x 150mm, symmetry column packed with octa decyl silane bonded to porous silica (C18) with particle size 5 micron with mobile phase containing TEA Buffer of pH 3.0 and Acetonitrile in proportion of 25:75 respectively. The flow rate was 1.0 ml/ min and effluent was monitored at 258 nm. The retention times were 2.39 min and 3.33 min respectively. The standard curve was linear over a working range of 05–35 µg/ml for both Amlodipine and Olmesartan and gave an average correlation coefficient of 0.999, and 0.999 for Amlodipine and Olmesartan respectively. The limit of quantitation (LOQ) of this method was 2µg/ml for Amlodipine and Olmesartan. The absolute recovery was 100% for Amlodipine and 100.3 for Olmesartan. Degradation products produced as a result of stress studies did not interfere with the detection of Amlodipine and Olmesartan and the assay can thus be considered stability-indicating.
A zero-range model for localized boundary stress on a tectonic plate with dissipative boundary conditions

We present spectral and scattering theories for a differential operator with a dissipation term that can be used to describe the dynamics of a tectonic plate with dissipative boundary conditions. The generating operator is non-selfadjoint causing some additional complexity. This difficulty has been overcome by developing the selfadjoint-dilation theory. We develop a functional model for the dissipative operator and the associated scattering theory of Lax-Phillips type. 1. Structure & dynamics of tectonic plates. By now the naive idea of the Earth as a hard body is viewed as far from reality. In fact the Earth is similar to an egg with a cracked shell. This shell - the lithosphere - is com- posed of numerous fragments - the most part covered by 14 large fragments, the tectonic plates. The scale of these large tectonic plates varies within a range of several thousand kilometers and bodies of neighboring plates contact directly along relatively small active zones with diameters of about 100 km. Along the remainder of the boundaries, neighbor- ing tectonic plates are often separated by relatively nar- row channels are filled with smaller fragments and disperse materials which cannot accumulate significant amounts of elastic energy, and so transform it into heat, causing the dissipation of stored elastic energy in the form of seismo- gravitational oscillations (SGO). These SGOs admit spec- tral interpretation, see (21, 44) and our discussion below. Tectonic plates are relatively thin (30-100 km thick) under the oceans, but are thicker (200-300 km) on the ancient continental platforms and along the oceanic ridges. The elastic properties of the plates are determined by Young's modulus 17.28 × 10 10 kg m −1 sec −2 , density 3380 kg m −3 and the Poisson coefficient 0.28. The velocity of longi- tudinal waves on the plates is about 8000 m sec −1 , and the velocity of the flexural waves depends on the frequency and varies, with the type of the wave, on a wide range around 4500 m sec −1 . The tectonic plates float on the as- tenosphere. The viscosity of the astenosphere is large for fast motions, but relatively small for slow ones. The exterior dynamics of the tectonic plates is defined by their sliding along the astenosphere (with liquid friction) by convective flows in the Earth's mantle and also due to changes of the rotation speed of Earth caused by fluctu- ations in the moment of inertia. Both factors are caused by irregularities in the energy dissappation from the liq- uid upper core (see §4). Though forced oscillations may be present in the tectonic system most of the elastic dynamics are defined by the SGO of the plates caused by variation of the strain-stress conditions at the active zones. These elastic properties of the plates can be described in terms of thin plate models floating on a liquid with appropriate boundary conditions analogous to the model of floating ice, see (10). Here we base our observations on the assump- tion of the spectral nature of SGO, see (21, 44). This is
Electroencephalographic Assessment of Player Experience

Psychophysiological methods, such as electroencephalography (EEG), provide reliable high-resolution measurements of affective player experience. In this article, the authors present a psychophysiological pilot study and its initial results to solidify a research approach they call affective ludology, a research area concerned with the physiological measurement of affective responses to player-game interaction. The study investigates the impact of level design on brainwave activity measured with EEG and on player experience measured with questionnaires. The goal of the study was to investigate cognition, emotion, and player behavior from a psychological perspective. For this purpose, a methodology for assessing gameplay experience with subjective and objective measures was developed extending prior work in physiological measurements of affect in digital gameplay. The authors report the result of this pilot study, the impact of three different level design conditions (boredom, immersion, and flow) on EEG, and subjective indicators of gameplay experience. Results from the subjective gameplay experience questionnaire support the validity of our level design hypotheses. Patterns of EEG spectral power show that the immersion-level design elicits more activity in the theta band, which may support a relationship between virtual spatial navigation or exploration and theta activity. The research shows that facets of gameplay experience can be assessed with affective ludology measures, such as EEG, in which cognitive and affective patterns emerge from different level designs.
HELP-SEEKING AND PERCEIVED HELPFULNESS OF FORMAL HELP SOURCES FOR VICTIMS OF DOMESTIC VIOLENCE: AN EXPLORATORY STUDY

The aim of this study is to gain an understanding of domestic violence victims’ help-seeking behavior and what they consider to be most helpful, taking into account legal changes such as criminalization of domestic violence (DV) and additional formal help sources available to the victims. Data was collected through semi-structured interview of five women that sought help from Vilnius City Specialized Help Centre (SHC) for DV victims. PTSD Symptom Scale—Self Report version five (PSS-SR5) was applied to determine the impact of domestic violence on a persons’ wellbeing. Results were driven from thematic data analysis of in-depth semi-structured interviews and were presented as themes. Results suggest that all women sought help from formal help sources such as police, intervention centers (Specialized Help Centers), and from medical and social services. The most helpful formal help source they found was from SHCs. In carrying out the State delegated function, they provided the best assistance and therefore rekindle the trust in the legal system as well as the State itself. All women experienced institutional violence and/or institutional betrayal. According to the results of PSS-SR5, high scores of post-traumatic stress disorder were the characteristics of the participants. Results can be used to enhance the knowledge of the women’s experience and their perception on what services are the most helpful. In addition, the result of this study is relevant to professionals working with domestic violence victims, policy makers, as well as scholars.
Acoustic Word Disambiguation with Phonogical Features in Danish ASR

Phonological features can indicate word class and we can use word class information to disambiguate both homophones and homographs in automatic speech recognition (ASR). We show Danish stød can be predicted from speech and used to improve ASR. We discover which acoustic features contain the signal of stød, how to use these features to predict stød and how we can make use of stød and stødpredictive acoustic features to improve overall ASR accuracy and decoding speed. In the process, we discover acoustic features that are novel to the phonetic characterisation of stød.
A more pragmatic Web 3.0: Linked Blockchain Data

Linked Data is proclaimed as the Semantic Web done right. The Semantic Web is an incomplete dream so far, but a homogeneous revolutionary platform as a network of Blockchains could be the solution to this not optimal reality. This research paper introduces some initial hints and ideas about how a futuristic Internet that might be composed and powered by Blockchains networks would be constructed and designed to interconnect data and meaning, thus allow reasoning. An industrial application where Blockchain and Linked Data fits perfectly as a Supply Chain management system is also researched.
Turnover Dynamics of Dendritic Actin Networks In Silico

regulation depends on the rapid turnover of dendritic actin networks, and this process is controlled by arp2/3 complex and capping protein. To understand how regulatory protein mediates the turnover dynamics, we construct a 3D computational model coupling stochastic reaction-diffusion processes with polymer mechanics. Our model sheds light on the way the turnover dynamics is affected by arp2/3 and capping protein concentrations and kinetics. Additionally, we find that treadmilling of preexisting filaments dominates the turnover, but the de novo assembly of filaments becomes significant when dissociation rate is slow.
ADMINISTRATION OF ADIPOSE-DERIVED STROMAL VASCULAR FRACTION AND PLATELET RICH PLASMA IN DOGS WITH COXOFEMORAL OSTEOARTHRITIS.

Objective: To evaluate the safety and effect of a single simultaneous intra-articular and intravenous injection of autologous adipose-derived stromal vascular fraction (SVF) and platelet rich plasma (PRP) on coxofemoral osteoarthritis (OA) in dogs. Methods: This was a randomized, double-blind, placebo-controlled prospective pilot trial of simultaneous intra-articular and intravenous SVF and PRP for coxofemoral OA. Dogs with coxofemoral OA causing signs of lameness or discomfort were evaluated by orthopedic exam, visual lameness score, Canine Brief Pain Inventory (CBPI), goniometry, visual analogue scale (VAS), and pressure-sensitive walkway (PSW) at week 0 (baseline), and at 4, 8, 12 and 24 weeks after injection. Joint radiographs were scored at 0 and 24 weeks. Results: Twenty two client-owned dogs with naturally occurring OA of the coxofemoral joints were enrolled (12 placebo-control, 10 SVF-treated). CBPI pain severity scores were lower in the treatment group at 24 weeks compared to the placebo group (p=0.042). The VAS score for the treatment group was significantly greater at 0 weeks than at 4, 8, or 24 weeks (p<0.05). When dogs with low quartile baseline PVF (25 percentile) were compared, the treatment group had statistically higher PVF at all post-injection time points when compared to the placebo group. After SVF injection, fewer dogs in the treated group were lame compared to the control group. Clinical Significance: This study is the first to utilize objective data from PSW as an outcome measure for dogs treated with SVF and PRP for coxofemoral OA. No adverse events were noted. Improvements in some measured parameters in the treated dogs compared to those in the placebo group.
Space-Indexed Control for Aircraft Vertical Guidance with Time Constraint

With the growth of civil aviation traffic capacity, safety and environmental considerations urge today for the development of guidance systems with improved accuracy for spatial and temporal trajectory tracking. This should induce increased practical capacity by allowing timely operations at minimum separation standards while at takeoff and landing and trajectory dispersion should be reduced, resulting in better controlled noise impacts on airport surrounding communities. Current civil aviation guidance systems operate with real-time corrective actions to maintain the aircraft trajectory as close as possible to a space-indexed planned trajectory while the flight management system copes indirectly with overfly time constraints. In this paper, the design of new longitudinal guidance laws is considered so that accurate vertical tracking is achieved while overfly time constraints are satisfied. Here, distance to land is adopted as the independent variable for the aircraft flight dynamics since it is today ava.
What It Takes to Achieve 100% Condition Accuracy on WikiSQL

WikiSQL is a newly released dataset for studying the natural language sequence to SQL translation problem. The SQL queries in WikiSQL are simple: Each involves one relation and does not have any join operation. Despite of its simplicity, none of the publicly reported structured query generation models can achieve an accuracy beyond 62%, which is still far from enough for practical use. In this paper, we ask two questions, “Why is the accuracy still low for such simple queries? ” and “What does it take to achieve 100% accuracy on WikiSQL? ” To limit the scope of our study, we focus on the WHERE clause in SQL. The answers will help us gain insights about the directions we should explore in order to further improve the translation accuracy. We will then investigate alternative solutions to realize the potential ceiling performance on WikiSQL. Our proposed solution can reach up to 88.6% condition accuracy on the WikiSQL dataset.
The Ethics of Lateral Hiring

ABSTRACT: Lateral hiring is the intentional action of one employer to identify, solicit, and hire an individual or group of employees currently employed by another firm, a practice often pejoratively labeled “poaching. ” We use the method of critical genealogy to demonstrate that the norms that discourage lateral hiring are constructions used by powerful employers to control the turnover of their employees, making them subjects of their employer’s power rather than free and autonomous people in their own right. We suggest instead that ethical responsibility for entertaining or rejecting lateral hiring offers rests with the focal employee(s). We conclude that the form and symmetry of loyalty between employees and their current employers are the determinants of the appropriateness of an employee’s decision to entertain and accept outside offers. These conclusions imply responsibilities for employers to forge (and employees to honor) symmetrical relational loyalty in the workplace, but not for alternate employers to refrain from making lateral hiring offers.
Mechanisms of Nanoparticle Formation by Laser Ablation

During the last decade, numerous experiments have been performed, clearly demonstrating that an interaction of a short (several nanoseconds or shorter) laser pulse with a solid target leads to the formation of nanoparticles. This technique, known as pulsed laser ablation (PLA), has become a promising method of the synthesis of nanoclusters for photonics, electronics and medicine (Movtchan et al., 1995; Yamada et al., 1996; Makimura et al., 1996; Geohegan et al., 1998; Albert et al., 2003). The PLA method has several advantages compared to more traditional techniques. In particular, it was shown that this method provides a possibility for chemically clean synthesis, which is difficult to achieve under more conventional nanoparticle production conditions. In addition, several experimental studies indicated that the cluster size distribution could be controlled in PLA by carefully choosing the laser irradiation parameters and properties of the background gas. Furthermore, laser ablation allows for an easy production of colloidal metal nanoparticles for biological and medical applications. Despite the large number of the experimental results, the theoretical understanding of the physical and chemical mechanisms leading to the formation of nanoparticles during the PLA is still lacking. The number of theoretical studies of these mechanisms remains limited because both the continuum hydrodynamic models and the classical nucleation theory become inapplicable under the typical PLA conditions. Under these conditions, laser plume expansion and all collisional processes inside the plume occur so rapidly that equilibrium conditions are not attained. In addition, fast laser energy deposition may induce an explosive volume ejection rather than an equilibrium surface evaporation. Nevertheless, the laser ablation process is often described by a thermal desorption model, which considers the ablation as a rather slow layer-by-layer evaporation of monomers from the target surface (Anisimov, 19968). The presence of nanoparticles in the laser plume is then explained by using a Zel’dovich-Raizer condensation model (Zeldovich, 1966; Luk’yanchuk et al., 1998; Gusarov et al., 2000). This approach is appropriate for interpretation of the experimental findings obtained in laser ablation with hundred of nanoseconds and longer laser pulses, and in the presence of a background gas (Ohkubo et al., 2003; Boldarev et al., 2001). In the PLA with shorter laser pulses, however, clusters can be ejected directly from the target as a result of the target disintegration by laser-induced explosion-like process (Bulgakov, 2004; Amoruso et al., 2004; Zhigilei, 2003). In this case, the common thermal desorption and
MLearning-PL: a pedagogical pattern language for mobile learning applications

FIORAVANTI, M. L. MLearning-PL: a pedagogical pattern language for mobile learning applications. 2018. 190 p. Dissertação (Mestrado em Ciências – Ciências de Computação e Matemática Computacional) – Instituto de Ciências Matemáticas e de Computação, Universidade de São Paulo, São Carlos – SP, 2018. The development and use of computational applications to support teaching and learning, together with the evolution of mobile computing, have contributed significantly to the establishment of a new learning modality known as mobile learning. Despite the benefits and facilities offered by educational applications, some problems and issues they present must be addressed. Challenges associated with mobile learning are not limited to developmental aspects or technologies. We should also consider the pedagogical aspects of this kind of application. When dealing with domain-specific software, we must be concerned about domain requirements. Therefore, it is important to have expert knowledge in the requirements engineering team and, in the case of mobile learning applications projects, such knowledge come from educators, teachers and tutors. However, capturing and transferring tacit knowledge are not trivial tasks and a supporting mechanism that guides the requirements elicitation phase in mobile learning applications projects would be of major importance. Pattern languages as a method to describe tacit knowledge is acknowledged and could be used as a supporting mechanism. Patterns constitute a mechanism for capturing domain experience and knowledge to allow such experience and knowledge to be reapplied when a new problem is encountered. Similarly, pedagogical patterns try to capture expert knowledge of the practice of teaching and learning. Aiming to solve, or at least diminish, the problems associated with mobile learning and due the lack of pedagogical patterns for this purpose, this work aims to create a pedagogical pattern language to assist the requirements elicitation phase of mobile learning applications projects. In this context, a pedagogical pattern language, named MLearning-PL, was created. It is composed of 14 patterns and focuses on assisting in the definition of mobile applications in order to keep learners motivated and committed to using such applications, considering their different learning styles and an effective knowledge acquisition. Experimental studies comparing MLearning-PL to an ad hoc approach in a pedagogical problem resolution scenario were conducted. The results obtained provided preliminary evidences of the applicability, effectiveness and efficiency of MLearning-PL.
Depression and Anxiety Among Infertile Moroccan Women: A Cross-Sectional Study in the Reproductive Health Center in Rabat

Objective: To determine the prevalence and severity of depression and the level of anxiety among infertile Moroccan women in relation to sociodemographic and fertility-specific characteristics.Methods: It is a cross-sectional study including 274 infertile women attending the Assisted Reproductive Technology Unit in the Reproductive Health Center of the University Hospital Ibn Sina in Rabat between June 2017 and February 2018. Two psychological tests were applied, the Beck Depression Inventory and the Hamilton Anxiety Rating Scale. Then, the association between the test scores and age, educational level, employment status, type of infertility, duration of infertility, and causes of infertility was examined.Results: The study showed that 55% of the women had depression and 45.6% had mild to severe anxiety. Depression and anxiety scores were low in employed women compared to unemployed women (p=0.002; p=0.006). There was no significant relationship between depression and anxiety and women's age or type of infertility. Anxiety had a significant relationship with duration of infertility (p=0.015), cause of infertility (p=0.034) and educational level (p=0.006) while depression had no significant relationship with these factors.Conclusion: The study findings showed that depression and anxiety were present in infertile Moroccan women and both were significantly associated with employment status while only anxiety was associated with educational level, duration and causes of infertility.