Miracle-dz/UniFAR-FTUs huggingface dataset:
Prevalence, antimicrobial susceptibility, serotyping and virulence genes screening of Listeria monocytogenes strains at a tertiary care hospital in Tehran, Iran

Background and Objectives: Listeria monocytogenes is the etiological agent of listeriosis, a highly fatal infection which causes miscarriage or stillbirth in pregnant women. The objective of this study was to detect the prevalence, serotypes, antimicrobial susceptibility and virulence factors of L. monocytogenes isolated from pregnant women with vaginitis at a tertiary care hospital in Tehran, Iran. Materials and Methods: During September 2015 to February 2017, a total of 400 vaginal swabs were collected from pregnant women. The presumptive isolates were characterized biochemically. All L. monocytogenes isolates were further analyzed by serotyping and antimicrobial susceptibility tests. All positive samples for L. monocytogenes were analyzed for presence of virulence genes (hlyA, actA, inlA, inlC, inlJ and prfA). Results: Twenty-two (5.5%) of the samples were found positive for presence of L. monocytogenes. Most isolates are resistant to trimethoprim/sulfamethoxazole (81.82%) and chloramphenicol (54.55%). The majority of tested isolates (59.10%) belonged to serotype 4b, followed by 1/2a (22.73%), 1/2b (13.63%), and 3c (4.54%). The hlyA, actA and inlA were detected in all of the 22 L. monocytogenes isolates, but two, three and five isolates were found to lack inlC, inlJ and prfA, respectively. Only one isolate lacked three inlC, inlJ and prfA genes, and two isolates simultaneously lacked both inlJ and prfA genes. Conclusion: Evaluation of virulence factors and antimicrobial susceptibility can be highly helpful to develop effective treatment strategies against L. monocytogenes infections. This study is noteworthy in that it documents prevalence, virulence characteristics, and antimicrobial resistance of L. monocytogenes.
Prevalence of trachoma in the Afar Region of Ethiopia: results of seven population-based surveys from the Global Trachoma Mapping Project

ABSTRACT Purpose: Trachoma is to be eliminated as a public health problem by 2020. To help the process of planning interventions where needed, and to provide a baseline for later comparison, we set out to complete the map of trachoma in Afar, Ethiopia, by estimating trachoma prevalence in evaluation units (EUs) of grouped districts (“woredas”). Methods: We conducted seven community-based surveys from August to October 2013, using standardised Global Trachoma Mapping Project (GTMP) survey methodologies. Results: We enumerated 5065 households and 18,177 individuals in seven EUs covering 19 of Afar’s 29 woredas; the other ten were not accessible. 16,905 individuals (93.0%) were examined, of whom 9410 (55.7%) were female. One EU incorporating four woredas (Telalak, Dalefage, Dewe, Hadele Ele) was shown to require full implementation of the SAFE strategy for three years before impact survey, with a trachomatous inflammation-follicular (TF) prevalence in 1–9-year-olds of 17.1% (95%CI 9.4–25.5), and a trichiasis prevalence in adults aged ≥15 years of 1.2% (95%CI 0.6–2.0). Five EUs, covering 13 woredas (Berahle, Aba’ala, Dupti, Kurri, Elidihare, Ayesayeta, Afamboo, Bure Mudaitu, Gewane, Amibara, Dulecho, Dalolo, and Konebo), had TF prevalences in children of 5–9.9% and need one round of azithromycin mass treatment and implementation of the F and E components of SAFE before re-survey; three of these EUs had trichiasis prevalences in adults ≥0.2%. The final EU (Mile, Ada’ar) had a sub-threshold TF prevalence and a trichiasis prevalence in adults just >0.2%. Conclusion: Trachoma is a public health problem in Afar, and implementation of the SAFE strategy is required.
Modeling of Configurations for Embedded System Implementations in MARTE

This paper deals with aspects related to modeling of system configurations, which are very useful for describing various states of an embedded system, from both structural and operational viewpoints. We discuss in detail the current proposition of the UML MARTE profile via some examples, and point out some limitations of the current proposition, mainly concerning the semantic aspects of the defined concepts. In ord er to draw answering elements, we report our experiences about the modeling of implementations and execution modes in Systems- on-Chip, within the Gaspard2 SoC co-design framework. I. I NTRODUCTION
A Locally Developed Electronic Health Platform in Uganda: Development and Implementation of Stre@mline

Background Electronic health records (EHRs) are especially important in low-resource settings due to their potential to address unique challenges such as a high number of patients requiring long-term treatments who are lost to follow-up, the frequent shortages of essential drugs, poor maintenance and storage of records, and inefficient clinical triaging. However, there is a lack of affordable and practical EHR solutions. Stre@mline is an EHR platform that has been locally developed by Ugandan clinicians and engineers in Southwestern Uganda. It is tailored to the specific context and needs of low-resource hospitals. It operates without internet access, incorporates locally relevant standards and key patient safety features, has a medication inventory management component, has local technical support available, and is economically sustainable without funding from international donors. Stre@mline is currently used by over 60,000 patients at 2 hospitals, with plans to expand across Uganda. Objective The purpose of this article is to describe the key opportunities and challenges in EHR development in sub-Saharan Africa and to summarize the development and implementation of a “Made-for-Africa” EHR, Stre@mline, and how it has led to improved care for over 60,000 vulnerable patients in a rural region of Southwestern Uganda. Methods A quantitative user survey consisting of a set of 33 questions on usability and performance was conducted at Kisiizi Hospital. Users responded to each question through a Likert scale with the values of strongly disagree, disagree, agree, and strongly agree. Through purposive sampling, 30 users were identified and 28 users completed the survey. Results We found that users were generally very satisfied with the ease of use of Stre@mline, with 96% (27/28) finding it easy to learn and 100% (28/28) finding it easy to use. Users found that Stre@mline was helpful in improving both clinical efficiency and enhancing patient care. Conclusions The partnership of local clinicians and developers is crucial to the design and adoption of user-centered technologies tailored to the specific needs of low-resource settings. The EHR described here could serve as a model for the development of future technologies suitable for developing countries.
Vanadyl Sulfate Effects on Systemic Profiles of Metabolic Syndrome in Old Rats with Fructose-Induced Obesity

Background Currently, energy obtained from hypercaloric diets has been part of the obesity and type 2 diabetes mellitus (T2DM) epidemics from childhood to old age. Treatment alternatives have been sought from plants, minerals, and trace elements with metabolic effects. Vanadyl sulfate (VS) has been investigated as a hypoglycemic compound in animal and human studies showing effective insulin-mimetic properties. This characteristic encompasses several molecules that have beneficial pleiotropic effects. The aim was to determine the antiobesity, hypoglycemic, and hypolipidemic effects of VS on fructose-induced metabolic syndrome in aged rats. Material and Methods Five groups of male Wistar rats were made, each with six rats: two groups with normal diet (ND) and three with high-fructose diet (HFD). The first ND group was treated with saline solution (SS), the second with VS; treatment for HFD groups was in the first group with SS, second with VS, and third with metformin. Weight, body mass index (BMI), blood glucose, and lipidic profile were measured; water, food, fructose and energy consumption were also determined. All parameters were compared among groups. Results and Discussion Although obese rats treated with VS presented anorexia, oligodipsia, and a marked weight loss in the first two weeks. They recovered food and water intake in the third week with a slow recovery of some weight weeks later. VS normalized blood glucose level and decreased triglyceride and insulin levels in obese rats. These results suggest that vanadyl sulfate shows antiobesity, hypoglycemic, and hypolipidemic properties in old obese rats and could be useful as an alternative, additional, and potent preventive treatment for obesity and T2DM control in elderly obese and poorly controlled diabetic patients. Conclusion VS could play an important role in the treatment of metabolic syndrome, contributing to a decrease in obesity and T2DM, through different ways, such as euglycemia, satiety, weight loss, and lipid profile optimization, among others. However, more research is needed to confirm this suggestion.
Recognition of Actual Grip Force Movement Modes Based on Movement-related Cortical Potentials

A new paradigm of grip force movement with parameters involving right and left hands is put forward in the study to meet the needs of brain-computer interface based brain-machine interaction control(BMIC) — direct brain-controlled robot interface(BCRI). Time-domain feature representation for grip force movement-related cortical potentials/movement-related potentials(MRPs) and the single-trial recognition of grip force movement modes are explored under the paradigm. EEG signals were picked up from eleven healthy subjects during four different tasks of right and left hands. Subjects were asked to execute voluntary grip movement at two modes of grip force variation. Each task was executed 30 times in a random order repeatedly. The features having significant difference among different grip force tasks are used for the classification of grip force modes by Fisher linear discrimination analysis based on kernel function(k-FLDA) and support vector machine(SVM), respectively. The study further demonstrates that MRPs may reflect brain neural mechanism process for planning, execution and precision of a given grip movement task. The average misclassification rates of 24 ± 4 % and 21 ± 5 % across eleven subjects are achieved by k-FLDA and SVM, respectively.The minimum misclassification rate is 12 % and the average of minimum misclassification rates across eleven subjects is20.9 ± 5 %. The study is expected to lay a foundation for follow-up comparative researches, which provide some additional force control intention instructions for BMIC/BCRI.
SimK： A Large-Scale Parallel Simulation Engine

模拟是一个重要方法评估未来计算机系统。 当前，微处理器建筑学换到平行，但是几乎所有模拟器在顺序的舞台留下了，并且优点由多核心带了或许多核心处理器不能被利用。 这篇论文向流行 SMP/CMP 站台论述一台平行模拟器引擎(SimK ) ，瞄准大规模有细密纹理的计算机系统模拟。 在这篇论文，高度有效的同步，通讯和缓冲区，在 SimK 使用的管理政策被介绍，并且用任何原子指令避免的新奇没有锁的安排机制被介绍。 为了在光处理负担变化，装载大小写，一个合作动态任务迁居计划被建议。 基于 SimK，我们开发了大规模平行模拟器 HppSim 和 HppNetSim，它分别地模仿一个完整的超级计算机系统和它的互联网络。 结果证明 HppSim 和 HppNetSim 两个都与多重处理器，和最好获得健全加速一个双向空铅核心服务者上的规范的加速活动范围 14.95X。
Accentuation in the technique of the Vedic poets

1. The role of accentuation in the Vedic poetics has never been investigated. Handbooks and studies on the metre and versification of the Rgveda (RV) only mention that accents have no impact on the metre. This is certainly correct, but poetics has more aspects than merely metre. Vedic Sanskrit had pitch accent, and a sequence of accents represented an accentual contour, a “melody”. By repeating or varying this melody poets could create different effects. The aim of this article is to demonstrate the relevance of accentuation for the technique of the Vedic poets. I shall first give a short account of Vedic accentuation and metre, followed by a survey of accentual poetical devices on the basis of examples taken from the second Mandof the RV. Finally, I shall analyze four Indra-hymns of this Mandviz. 2.12 – 2.15. 2. Vedic accentuation is known from accentuated manuscripts, grammatical treatises and modern recitation. Vedic accent was a pitch accent. The main accent of a word is termed udtta
Pharmaceutical Applications of Chemometric Techniques

Chemometrics involves application of various statistical methods for drawing vital information from various manufacturing-related processes. Multiway chemometric models like parallel factor analysis (PARAFAC), Tucker-3, N-partial least square (N-PLS), and bilinear models like principle component regression (PCR) and partial least squares (PLS) have been discussed in the paper. Chemometric approaches can be used to analyze the data obtained from various instruments including near infrared (NIR), attenuated total reflectance Fourier transform infrared (ATR-FTIR), high-performance liquid chromatography (HPLC), and terahertz pulse spectroscopy. The technique has been used in the quality assurance and quality control of pharmaceutical solid dosage forms. Moreover, application of chemometric methods in the evaluation of properties of pharmaceutical powders and tablet parametric tests has also been discussed in the review. It has been suggested as a useful method for the real-time in-process testing and is a valuable process analytical tool.
Fault-tolerant back-propagation model and its generalization ability

This paper presents a learning algorithm for multilayer neural networks that brings out the potential ability of fault-tolerance in the network. Experimental results show that fault-tolerant networks obtained by the proposed algorithm also have better generalization ability. The close relationship between fault-tolerance and generalization ability is discussed with some simulation results that clearly illustrate this property.
Measuring the Compatibility Factors in Mobile Entertainment Service Adoption

This study examines compatibility factors that influence users' intention to adopt mobile entertainment service. Potential compatibility factors derived from previous research include (1) compatibility with past control experience, (2) compatibility with user's curiosity and intrinsic interest, (3) compatibility with social norms, (4) compatibility with perceived critical mass, (5) compatibility with preferred lifestyle and (6) compatibility with economical value. From survey conducted in South Korea, curiosity & intrinsic interest, social norms, preferred lifestyle and economic value were found to have positive influence on the intention to adopt mobile entertainment service. The results imply that MES provider must select the most appropriate techniques and features to enhance the level of intrinsic interests among users. In addition, MES provider should concern about cultural orientation and life style of users during development of MES contents and interface as well as marketing of MES service.
Kinship care in the UK: using census data to estimate the extent of formal and informal care by relatives

Until recently, little was known about kinship care in the UK. Research has begun to illuminate the circumstances which lead to children being cared for by relatives, and the stresses and strains experienced by carers. However, most UK research has only considered ‘looked-after’ children placed with formal approved kinship foster carers, although this group forms the smallest proportion of children in kinship arrangements. In this paper, we use microdata from the 2001 UK Population Census to examine the characteristics of kinship carers and children, and demonstrate that most children in kinship care are growing up in informal unregulated arrangements. Implications for policy and practice are discussed.
Acute Physiological Effects of Exercise in Water

Abstract The acute effects of exercise in water may differ from those on land because of the physical properties of the water. The increased hydrostatic pressure causes a hypervolaemia, which influences the haemodynamic effects of exercise in water. Water resistance and temperature affect the metabolic pathways utilized during exercise. As a result the use of land-based norms to prescribe and monitor water exercise may be unreliable. This review focuses on upright exercise in water, namely cycle ergometry and walking/running. Oxygen consumption (VO2) and heart rate are influenced by the depth and temperature of the water, exercise mode and speed. For example, cycle ergometry on land and in water yield similar maximal oxygen uptake (VO2max) responses. However, shallow water running elicits a VO2max which is approximately 10% lower than similar land activity. Deep water running yields a 26% lower VO2max than on land. Cycle ergometry and walking/running in water have been shown to provide cardiovascular benefits in line with the American College of Sports Medicine guidelines. However a complex interaction exists between the water, exercise and subject variables which will affect the exercise response. Future research should focus on the biomechanical and neuromuscular effects of exercise in water at various depths.
TÜRKİYE'DE SALEP ORKİDELERİ VE SALEP KÜLTÜRÜ

Cicekli bitkilerin en genis familyalarindan biri Orkidelerin de icinde bulundugu Orchidaceae familyasidir. Dunya uzerinde 18.000-20.000 turu bulunan Orkideler ulkemizde dogal olarak yetismektedir. Bu Salep orkideleri, yiyecek-icecek, bitkisel ilac (drog) ve afrodizyak etkisi gibi cok farkli amaclarla kullanilmaktadir. Nitekim ulkemizde de Anacamptis, Himantaglossum, Ophrys, Orchis, Serapias gibi Orkidelerin yumrulari salep ve dondurma yapiminda kullanilmaktadir. Salep kulturu ile ilgili bu calisma; Adana, Hatay, Kahramanmaras, Osmaniye, Pozanti, Mut, Gulnar, Erdemli, Silifke, Tarsus ve Ermenek bolgelerinde 2005-2007 yillari arasinda yurutulmus ve 37 soruluk bir anketin 103 kisiye uygulanmasi ile veriler toplanmistir. Ankete katilan ve salep bitkisini taniyan bireylerin onemli bir bolumu koruma kullanim dengesinin olusturulmasi gerektigi noktasinda birlesmis, diger bolumu de kontrolsuz toplama isleminin bitirilmesinde ekonomik gerekcelerin bulundugunu ileri surmuslerdir.
Calibration of the Aw-Rascle traffic flow model via flow-density diagram data

The Aw-Rascle (AR) model has attracted more and more attention, because it solves the problem of the anisotropic property of traffic flow which is proposed by Daganzo. The AR model possesses an increasing function of the density which be called as the pressure function. The calibration of the pressure function is a primary work in the research of the model application. In this paper, we calibrate the pressure function of the AR model via flow-density diagram data. Our approach is to rewrite the Lighthill-Whitham-Richards (LWR) model to the form of velocity evolution equation which based on flow-density diagram and then contrast with the velocity term of AR model. Finally, we employ the PeMS detector data as flow-density diagram data to construct the pressure function, and apply the NGSIM trajectory data to be the initial and time-dependent boundary data. Via these two data sets, we predict the traffic state at interior space in the near future using the calibrated AR model and classical AR model respectively, and compare the predicted data with real traffic data to verify the feasibility and accuracy of this calibration.
Contingency Assessment of Radial Distribution System

The purpose of the investigation presented in this paper is to obtain the optimal restructure of radial distribution system under the impact of contingencies, with and without the scope of distributed generation. Firstly, solution to occurrence of contingency is proposed by finding out the best switching sequence of a specified number of tie lines and sectionalizes with an objective to improve the continuity of power flow in radial system. Secondly genetic algorithm (GA) has been used to find the optimal location and size of embedded distribution generation (DG), to improve voltage profile and to reduce losses for given load demand. The outcome of the proposed study is illustrated through simulations of loaded 69-bus radial distribution system. The obtained results suggest that the investment is distribution generation is attractive when reconfiguration is used to minimize load curtailment.
The archaeology of San Antonio's main plaza, investigations at 41BX1753

Acknowledgements I would like to thank everyone at PBS&J including Clell Bond, Eugene Foster, and Nesta Anderson PhD. for giving me the opportunity to get involved in the Main Plaza Project, Mike Smith for putting up with me every day in the field, for all the help in the field and in the lab, and Brandy Harris for too many things to list. I " d also like to thank Kay Hindes with the City of San Antonio and Mark Denton from the Texas Historical Commission for their guidance and time. The field effort would not have been possible without the patience and skill of me make a silk purse out of a sow " s ear and Darrell Creel PhD. for helping me in a time of need. I would like to thank my parents for their encouragement and my brother for his questions about cannon balls. Most importantly, I have to thank my wife, Susan for her love and support and for making this fun. This thesis documents the fieldwork component of the archaeological survey, testing, and data recovery efforts associated with 41BX1753, a historic-age site located in downtown San Antonio, Texas. This paper details the project " s activities and results and provides feature and artifact descriptions. Furthermore, this work provides a contextual analysis of 41BX1753 based on the artifacts recovered and the archival record. In the report, I explore the social, political and economic relationships in San Antonio " s past through the study of the material and archival records associated with a single property and its residents. Examined within a greater historical context, these records are indicative of choices made by some of San Antonio " s most influential residents indicating vii a sense of identity and status, as well as strategies of adaptation and accommodation to ensure stability in the face of constant change.
RL-MLZerD: Multimeric protein docking using reinforcement learning

Numerous biological processes in a cell are carried out by protein complexes. To understand the molecular mechanisms of such processes, it is crucial to know the quaternary structures of the complexes. Although the structures of protein complexes have been determined by biophysical experiments at a rapid pace, there are still many important complex structures that are yet to be determined. To supplement experimental structure determination of complexes, many computational protein docking methods have been developed; however, most of these docking methods are designed only for docking with two chains. Here, we introduce a novel method, RL-MLZerD, which builds multiple protein complexes using reinforcement learning (RL). In RL-MLZerD a multi-chain assembly process is considered as a series of episodes of selecting and integrating pre-computed pairwise docking models in a RL framework. RL is effective in correctly selecting plausible pairwise models that fit well with other subunits in a complex. When tested on a benchmark dataset of protein complexes with three to five chains, RL-MLZerD showed better modeling performance than other existing multiple docking methods under different evaluation criteria, except against AlphaFold-Multimer in unbound docking. Also, it emerged that the docking order of multi-chain complexes can be naturally predicted by examining preferred paths of episodes in the RL computation.