Miracle-dz/UniFAR-FTUs huggingface dataset:
The Platform Business Model Canvas a Proposition in a Design Science Approach

Literature research has shown that there is no proven business model canvas for platforms. Such a canvas would be a vital tool that provides added value to companies and innovators for various purposes: sharing, communication (internal and external), description, analysis, management, planning and partnering. In addition, a platform business model canvas helps follow a systematic but also pragmatic approach with regards to the transformation of a pipeline business to a platform business, the task to design a new platform or to describe an existing platform business model. The goal of this research is therefore to create a platform business model canvas that is easy to use and helps capture platform business models in a comprehensive and effective way following the Design Science Approach. The basic components/building blocks and the necessary perspectives for the platform business model canvas, are derived from literature. The need for three or more perspectives, is furtherly discussed on basis of Osterwalder’s business model canvas by outsourcing dimensions of control. Components and perspectives are subsequently verified through a qualitative analysis of the about-us-pages of 32 platform websites. The components/building blocks and perspectives are then put together to form a platform business model canvas, which is then evaluated through an illustrative case study explaining the platform business model of eBay.
Efficiency of Internal Marketing Dimensions in Private Universities of Kurdistan Region to Achieve the Organizational Commitment

The current paper attempts to study the effectiveness of internal marketing (IM) dimensions as an effective internal tool for the economic unit to enhance the organizational commitment (OC) in the private universities of Kurdistan Region. The importance of the research can be stemmed from the important role of IM in the economic unit, which can increase the activity of economic unit and achieve the OC in private universities of Kurdistan Region. So, the applying of IM in the economic unit effectively can help to strengthen the loyalty of the employees and help economic units to keep their employees. The researchers concluded that there is a good level of agreement for the employees of private universities in Kurdistan Region of Iraq about the activities of IM in the study sample and their role to enhance OC. The researchers recommended making more efforts for meeting the material and moral needs of the employees and gaining their satisfaction to ensure their continued work and keep them from thinking about moving to other economic units.
Opossum Mammary Maturation as It Relates to Immune Cell Infiltration and Nutritional Gene Transcription

Synopsis The mammary gland has evolved to accommodate the developmental needs of offspring in species-specific ways. This is particularly true for marsupials. Marsupial milk content changes dramatically throughout lactation in ways appearing timed with neonatal ontogeny and behavior. Here we investigate morphological restructuring within the mammaries throughout lactation in the gray short-tailed opossum, Monodelphis domestica. Substantial remodeling of the mammaries occurs throughout the first half of active lactation. It is not until the latter half of lactation that opossum mammaries appear histologically similar to active eutherian mammaries. Noteworthy was the presence of eosinophils in early developing mammary tissue, which correlated with elevated abundance of transcripts encoding the chemokine IL-16. The presence and abundance of whey protein transcripts within the opossum mammaries were also quantified. Whey acidic protein (WAP) transcript abundance peaked in the latter half of lactation and remained elevated through weaning. Minimal transcripts for the marsupial-specific Early and Late Lactation Proteins (ELP/LLP) were detected during active lactation. Elevated abundance of LLP transcripts was only detected prior to parturition. Overall, the results support the role of eosinophils in mammary restructuring appearing early in mammalian evolution, and describe key similarities and differences in nutritional protein transcript abundance among marsupial species.
Association of Adjuvant Radiotherapy With Survival After Margin-negative Resection of Pancreatic Ductal Adenocarcinoma

Supplemental Digital Content is available in the text Introduction: There is conflicting evidence for the benefit of adjuvant radiotherapy (RT) after resection of pancreatic ductal adenocarcinoma (PDAC), especially for margin-negative (R0) resections. We aimed to evaluate the association of adjuvant RT with survival after R0 resection of PDAC. Methods: Using National Cancer Database (NCDB) data from 2004 to 2013, we identified patients with R0 resection of nonmetastatic PDAC. Patients with neoadjuvant radiotherapy and chemotherapy and survival <6 months were excluded. Propensity score matching was used to account for treatment selection bias. A multivariable Cox proportional hazards model was then used to analyze the association of RT with survival. Results: Of 4547 (36%) RT and 7925 (64%) non-RT patients, 3860 RT and 3860 non-RT patients remained in the cohort after matching. Clinicopathologic and demographic variables were well balanced after matching. Lymph node metastases were present in 68% (44% N1, 24% N2). After matching, RT was associated with higher survival (median 25.8 vs 23.9 mo, 5-yr 27% vs 24%, P < 0.001). After multivariable adjustment, RT remained associated with a survival benefit (HR 0.89, 95% CI 0.84–0.94, P < 0.001). Stratified and multivariable interaction analyses showed that this benefit was restricted to patients with node-positive disease: N1 (HR: 0.68, CI95%: 0.62–0.76, P = 0.007) and N2 (HR: 0.59, CI95%: 0.54–0.64, P = 0.04). Conclusions: In this large retrospective cohort study, adjuvant RT after R0 PDAC resection was associated with a survival benefit in patients with node-positive disease. Adjuvant RT should be considered after R0 resection of PDAC with node-positive disease.
Controle de Sistemas Variantes no Tempo: uma abordagem alternativa à técnica de controle via transformação Lyapunov-Floquet

: It is known in the literature that the Lyapunov-Floquet transformation control technique can be applied in time-varying systems. However, the asymptotic stability of the system is not mathematically guaranteed. In this work the robust control theory is approached aiming its application in time-varying systems. This method is based on obtaining the representation of the system as a convex combination of the maximum and minimum of the variant terms of the matrices that determine the system. As will be seen, the robust control technique allows to obtain suﬃcient stability condition for linear time-varying systems, via LMIs. Finally, applications of this technique are presented in two systems, one linear and the other nonlinear. Resumo
A User-Centered Ergonomic Keyboard Design to Mitigate Work-Related Musculoskeletal Disorders

Work-related musculoskeletal disorders are amongst the most prevalent occupational disorders around the United States [1]. Acknowledging ergonomic variables, such as the architecture of workplace computer equipment, may well reduce the likelihood of employees forming musculoskeletal disorders [2]. This work portrays what we understand from research regarding the impact of workplace ergonomic interventions as it relates to the computer keyboard. Classic QWERTY computer keyboard designs are no longer constrained to the conventional horizontal configuration that are ordinarily packaged with individual computers. Now, there are keyboards which are partitioned into two sections, and these haves can have keys oriented at an angle, sloped down to the visual display terminal, or tilted up forming a geometric triangular shape [3]. These interventions are intended to position upper limbs in a more natural orientation resulting in pain alleviation, and a reduction in likelihood of musculoskeletal disorder development from the repetitive use of conventional computer keyboards [1]. Research efforts reviewed in this work also illustrate that experienced typists quickly adapt to alternative keyboard features, and are just as productive in terms of words per minute output. A proposed ergonomic computer keyboard design (Trinity) delivered in this paper maintains the integrity of literature by integrating insights from previous works to reduce musculoskeletal disorders while maintaining interactive user productivity.
Associations between Magnetic Resonance Imaging Detected Intraplaque Hemorrhage and Carotid Artery Atherosclerotic Plaque Components in Mild to Severe Stenotic Non-surgical Patients

Stroke represents a major cause of death globally. One major cause of stroke is atherosclerosis, especially when developed in carotid arteries. Certain plaque components, such as intraplaque hemorrhage (IPH), lipid-rich necrotic core (LRNC), calcification, and high vessel wall (VW) volume are critical determinants for the stability of a plaque and can now be identified noninvasively with multicontrast magnetic resonance imaging (MRI). This thesis examined the feasibility of using a standardized multicontrast MRI protocol in a multicenter setting with only clinically available hardware and software and showed over 90% of patients had acceptable quality images to allow study of plaque components quantitatively. This thesis also examined the quantitative relationship of IPH with other plaque components. Specifically, the volume of IPH was significantly associated with volume of VW and LRNC but not calcification. Our results provided quantitative insights of IPH and may facilitate the planning of future multicenter endeavors studying carotid atherosclerosis.
Special care units in nursing homes -- selected characteristics 1996.

This report from the Agency for Health care Policy and Research (AHCPR) summarizes information on special care units in nursing homes with emphasis on Alzheimers units. This information comes from the 1996 Nursing Home Component (NHC) of the Medical Expenditure Panel Survey (MEPS). In 1996 almost a fifth (19.2 percent) of all nursing homes had at least one formal and distinct special care unit. These special care units contained 120400 beds or 6.9 percent of all nursing home beds. By far the largest category of special care units was for Alzheimers and related dementias which constituted 65.7 percent of all the special care units in nursing homes. More than a tenth (12.6 percent) of nursing homes--or 2130 homes--had an Alzheimers unit. The number of beds in these units totaled 73400. Hospital-based nursing homes were less likely than other facility types to have special care units. Special care units were more likely to be found in nursing homes that were part of a group or chain than in independent facilities. There was also a clear correlation between the number of nursing beds in the facility and the probability that the facility contained a special care unit. Nursing homes with special care units were more likely than other facilities to be certified by both Medicare and Medicaid. (authors)
Bio-behavioural evaluation of efavirenz and Δ9-tetrahydrocannabinol alone and in combination in rats with respect to psychosis and anxiety

for basic pharmacology podium presentation at the South African Society for Basic and Clinical Pharmacology congress, 7-10 October 2018, Spier Conference Centre, Stellenbosch, and Cape Town, South Africa. The student, as first and presenting author, won the 3 prize in the “Basic Pharmacology” category.
Key Experiences and Non-monetary Resources Impacting Stakeholder Satisfaction, Growth, and Effectiveness in Educational Settings

“If we teach today’s students as we taught yesterday’s, we rob them of tomorrow. ” John Dewey The traditional role of education in this country has been to prepare the next workforce. This role has been responsible for teaching children through the colonial, agricultural, industrial, mechanical, computerized, and presently the innovation era. This new era opens a whole new world for educators. A common phrase teachers have heard has been about preparing students for jobs that haven’t been created yet. Teachers also have been told about the skill set this generation of students will need to be successful. The World Economic Forum published an article titled, “The Most Important Skills of Tomorrow, According to Five Global Leaders. ” The five skills (or practices) they recognized were as follows: 1. Soft Skills, (interpersonal skills including communication, empathy, listening, etc.) 2. Data Literacy with A Strong Dose of Empathy 3. Skills That Computers Will Never Likely Master 4. Transferable Skills 5. An Entrepreneurial Spirit and The Skills to Know How to Apply it Recently, Wagner and Dintersmith (2015) teamed together to write a book, which has since become a movie, entitled Most Likely to Succeed, Most Likely to Succeed: Preparing our Kids for the Innovation Era. In their book, the authors lamented the time students wasted learning “what can be outsourced on their smartphones” and not the skills they need (Wagner & Dintersmith, 2015, p. 5). The skills relevant to this study
Big Data and Emergency Management: Concepts, Methodologies, and Applications

Recent decades have seen a significant increase in the frequency, intensity, and impact of natural disasters and other emergencies, forcing the governments around the world to make emergency response and disaster management national priorities. The growth of extremely large and complex datasets—commonly referred to as big data—and various advances in information and communications technology and computing now support more effective approaches to humanitarian relief, logistical coordination, overall disaster management, and long-term recovery in connection with natural disasters and emergency events. Leveraging big data and technological advances for emergency management has attracted considerable attention in the research community. However, the desired merging of big data and emergency management (BDEM) requires coordinated efforts to align and define interdisciplinary terminologies and methodologies. To date, the key concepts and technologies in this emerging research area have not been coherently discussed in a sufficiently broad and multidisciplinary manner. In this article, an international team presents an overview of the BDEM domain, highlighting a general framework and discussing key challenges from several perspectives. We introduce and summarize typical technologies and applications, organized into the six broad categories of remote sensing, resilient communication networks, mobile communication networks, human mobility and urban sensing, social network analysis, and knowledge graphs. Finally, we outline several directions of future research.
Propuesta de un Modelo de Humanización basado en las Competencias Personales: Modelo HUMAS

A pesar de que hoy en día el concepto de Humanización está muy presente en el entorno de los cuidados, no existe una definición clara sobre qué puede entenderse por humanización de los cuidados. Con el objetivo de colaborar en la concreción de un término que posee una clara composición multifactorial, se plantea la creación de un modelo que permita explicar las competencias y actitudes que debe desarrollar un profesional sanitario para incorporar la Humanización en el ejercicio de su profesión. En el modelo propuesto, la Humanización se define como un conjunto de competencias personales que permiten desarrollar la actividad profesional, dentro del ámbito sanitario, velando por la dignidad y el respeto hacia el ser humano. Es, por tanto, una actividad enfocada a la mejora del cuidado de la salud, tanto física como mental y emocional, dirigida tanto a pacientes y familiares, como a los propios profesionales sanitarios. El modelo teórico propuesto HUMAS, está centrado en los procesos psicológicos, en las competencias personales que capacitan a los profesionales sanitarios para ofrecer al paciente una atención de calidad. Así, el profesional, contando con todos los recursos disponibles en el sistema sociosanitario y en el entorno del paciente, además requiere de la adquisición y el desarrollo de competencias personales entre las que se encuentra la disposición al optimismo, la sociabilidad, la compresión emocional, la autoeficacia y la afectación, entendidas como esenciales para contribuir a un desempeño profesional positivo, basado en la humanización, como es el modelo HUMAS.
Evaluation the Effects of Eucalyptus Essential Oil and Hypertonic Saline as Scolicidal Agents in Induction of Sclerosing Cholangitis in Rabbits

Background: There are several scolicidal agents for inactivation of hydatid cyst protoscolices during surgery, but most of them are associated with adverse side effects such as sclerosing cholangitis (SC) and liver necrosis. The present study aimed to evaluate the adverse effects of Eucalyptus essential oil to induce SC in animal models. Materials and Methods: Eighteen rabbits weighting 2000–3500 g were included in three groups for this study. About 0.3 ml of Eucalyptus essential oil (1%), or 5% hypertonic saline, or normal saline was injected for 5 min in the gallbladder. After 4 months, the liver, common bile duct, and duodenum were resected and immediately sent for cholangiography and pathologic studies. Results: According to pathological studies, inflammation is more common in Eucalyptus and hypertonic saline groups. Due to cholangiographic studies, stricture was slightly higher in the hypertonic saline group than the Eucalyptus group. Conclusion: Thus, 1% Eucalyptus essential oil is at least as safe as 5% hypertonic saline, but for clinical uses, it must be confirmed with further studies.
Molluscan aquaporins: an overview, with some notes on their role in the entry into aestivation in gastropods

ABSTRACT The transport of water and small uncharged molecules across prokaryotic and eukaryotic cell membranes is supported by aquaporins. In spite of their importance, molluscan aquaporins have not been thoroughly explored. This is worth addressing since data concerning water channels in molluscs generally shed new light on aquaporins. Our analysis of these proteins revealed a novel composition of amino acids in the ar/R region, a unique group of aquaporins in phylogenetic relationships, and the impact of environmental conditions on water channels. Additionally, we present new research about changes in the expression level of Helix pomatia aquaporins during entry into the state of aestivation. Transcriptome expression patterns obtained for feet, kidneys, and intestines from active snails housed for 3, 7, 15, and 35 days without food or water confirm the importance of aquaporins in counteracting water stress.
Comparison of Methods for Determining Activity from Physical Movements

In this study, the methods which can detect the basic physical movements of a person (downward, upward, sitting, stop, walking, running) from inertial sensor (IMU) data are evaluated. The performances of classical (ANN, SVM, k-NN) and current approaches (Convolutional Neural Networks-ESA) to map IMU data to activity classes were compared. A three-stage study was carried out for this aim: 1) data acquisition; 2) creating training/test sets; 3) construction and classification of network architectures. At the stage of data acquisition, to obtain 6 different physical movements from 10 different people, the accelerometer sensor is placed on the persons. Repetitive movements of persons were recorded. At the second stage, the recorded long-term accelerometer data is divided into packages in the form of short-term windows. The training set of classical approaches was constructed by features extracting from each packet data containing one-dimensional acceleration information. The transformation of one-dimensional signals to a two-dimensional image matrix for the training set of the deep learning-based approaches was performed. In the third stage, ANN, SVM, k-NN and CNN architectures were constructed, and classification process was carried out. As a result of the experimental studies, it was found that the accuracy of IMU-activity mapping was 99% with the ANN method and 95% with the CNN method.
Strategic Attacks on Recommender Systems: An Obfuscation Scenario

Understanding user behavior in the context of recommender systems remains challenging for researchers and practitioners. Inconsistent and misleading user information, which is often concealed in datasets, can inevitably shape the recommendation results in certain distorted ways despite utilizing recommender models with enhanced personalizing capabilities. Naturally, the quality of data that fuels those recommenders should be extremely reliable and free of any biases that might be invisible to a model, irrespective of its type. In this article, we introduce two modern forms of noise that are intrinsically hard to detect and eliminate; one is malicious in nature and will be termed Burst while the other is unique in that it forms its own category and will be referred to as Opt-out. Additionally, with the aim of segregating the nature of noise behind such threats, we present a distinct case study on Burst and Opt-out to illustrate how the detection of those threats can be challenging compared to that of traditional noise and with the current detection methods. Finally, we expound on the ability of such threats to bias the output of recommenders in their own unique way while primarily retaining data that is not fundamentally erroneous.
Purification of coated vesicles from synaptosomes from bovine brain

A pure fraction of coated vesicles (CVs) was prepared from crude washed synaptosomes from bovine brain. Impurities, synaptic vesicles (SVs) and membrane fragments of uncertain origin, were eliminated by differential and linear sucrose density gradient centrifugation. All puriﬁcation steps were monitored by electron microscopy. The purity of the last coated-vesicle fraction was very satisfactory, being free of synaptic vesicles with only a few contaminating membrane fragments. Coated vesicles (CVs) with a ubiquitous distri-bution in eukaryotic cells participate in various cellular processes involving receptor-mediated endocytosis (1). It has been suggested that the CVs in presynaptic terminals retrieve a part of the plasmalemmal excess resulting from the exocytosis of hormone-storage granules or synaptic vesicles (SVs) and are transformed into SVs by shedding the outer coat structure (4-6, 11, 22). One way of clarifying CV functions in nerve endings has been to purify the vesicles and characterize their biochemical and mor-phological properties, in order to examine the recycling pathways of SV membrane (7). Several methods for isolating and purifying CVs from whole brain tissues are currently in use (10, 15-17, 21), and many studies have been published on the chemical composition and ﬁne structures of CVs (3, 9, 10, 13, 15-17, 19-21). We have attempted to develop a new method for purifying CVs from bovine brain synaptosomes to facilitate biochemical investigation of the functions of presynaptic CVs.