Miracle-dz/UniFAR-FTUs huggingface dataset:
Laparoscopic bariatric surgery in a patient with idiopathic intracranial hypertension and lumboperitoneal shunt: Anesthetic implications

Idiopathic intracranial hypertension (IIH) typically affects obese young women. Treatment is mainly medical, but some cases require surgery; ventriculoperitoneal (VPS) or lumboperitoneal shunts (LPS) being the most common procedures. Although bariatric surgery is not the first-line surgical treatment, it can be useful in refractory cases and allows treating the major underlying risk factor and its comorbidities. Laparoscopic bariatric surgery is the gold standard; however, literature in patients with shunts is scarce. In the present study, we report the case of a morbidly obese female with IIH treated with an LPS and with refractory headache, scheduled for laparoscopic Roux-en-Y gastric bypass. LPS position was checked before surgery (abdominal X-ray) and during pneumoperitoneum was clamped. Anesthetic management was guided to minimize increases in intracranial pressure (ICP). Surgery and anesthesia were uneventful. Three months later, headaches disappeared and analgesics were discontinued. In conclusion, laparoscopic bariatric surgery may be an option for IIH. It is safe in patients with LPS, although concerns should be taken into account (avoid any damage to the shunt, limit digestive tract contents spillage, and strict vigilance for early detection of intracranial hypertension signs). Although valve system could prevent pressure complications, the catheter can be clamped to avoid retrograde insufflation of CO2 or digestive tract content.
The application of magnetic resonance imaging-guided microwave ablation for lung cancer

Context: It is necessary to explore a minimally invasive, effective, and efficient treatment for those lung cancer patients who are poor candidates for surgery. Aim: This study aimed to investigate the application of microwave ablation (MWA) in the treatment of lung cancer. Settings and Design: A total of 43 patients with 44 pulmonary lesions were examined following identical procedures before being randomly divided into two groups. The experimental group consists of 17 patients with a total of 18 pulmonary lesions, while the control group consists of 26 patients with a total of 26 pulmonary lesions. Materials and Methods: The experimental group was treated using magnetic resonance imaging (MRI)-guided MWA while the control group was treated using computer tomography (CT)-guided MWA. A transverse relaxation time-turbo spin echo (T2-TSE) sequence was used for signal collection in the experimental group to determine puncture location and microwave needle position while T2-TSE, T1-turbo field echo, and diffusion-weighted MRI (DWI) sequences were used for timely efficacy evaluation. Whereas in the control group, CT axial scanning was performed to serve similar purposes. Statistical Analysis Used: A nonparametric Wilcoxon test, median (M [25%, 75%]). Results: All of the 44 lesions were successfully located on the first attempt. The mean time for scanning and locating lung lesions under MRI and CT guidance were 64.53 and 42.96 min, the mean times of positioning were 12 and 18 min, and the mean durations of MWA were 12.48 and 15.06 min, respectively. Conclusions: As a minimally invasive method for treating lung tumors, MRI-guided MWA requires fewer localization scans, a shorter MWA duration, no radiation, real-time observation of the curative effect, and it prevents overtreatment.
Role of Phenytoin in Diabetic Foot Ulcers

Of the complications of diabetes mellitus, foot ulcers are the most dreaded complications, as they can progress at an alarming rate and can be very difficult to treat. Various modalities have been described in the treatment of diabetic foot ulcers. One such modality of phenytoin therapy uses the disadvantage of the drug, that is, gingival hyperplasia to the advantage of wound healing. We hereby report a case of diabetic foot ulcer managed with injection phenytoin sprayed topically over the wound.
Oral teratoma in a neonate: A case report of anesthetic challenge

Congenital teratoma of oral cavity in a neonate is a rare condition associated with compromised airway and challenges anesthesiologist in airway management. In this report, we describe a scenario of neonate with multiple oral teratoma, cleft palate, and bifid tongue who presented with respiratory distress for surgical excision of mass. The compromised airway can be successfully managed by appropriate prior planning and effective communication between anesthesiologist and surgical team.
Prebiotic prophylaxis of abdominal bloating in mechanically ventilated patients fed through nasogastric tubes: A randomised clinical trial

Objective: Enteral nutrition is the first choice of nutritional support of patients undergoing mechanical ventilation. Gastrointestinal disorders, especially abdominal bloating, are commonly seen in this group of patients. Given the prevalence of bloating and its perceived severity, the lack of an effective method for the control or treatment of this problem during mechanical ventilation is urgently felt. Materials and Methods: This double-blind, randomised, controlled clinical trial was conducted on 60 mechanically ventilated patients divided in two groups (n = 30). The study group received fenugreek seed (FS) powder by gavage twice a day besides the routine care. The control group only received routine care. Abdominal bloating, consisting of abdominal pain intensity, abdominal circumference, vomiting, frequency deification, bowel sounds and gastric residual volume, was measured at the baseline and every day for 5 days. Results: By the end of study, abdominal bloating decreased significantly in the study group compared to controls (P < 0.05). Conclusion: Given that even a slight reduction in symptoms can produce positive public health consequences, daily diet with FSs is recommended for critically ill patients.
Applicability Of Wireless Sensor Networks & Iot In Saffron & Wheat Crops: A Smart Agriculture Perspective

: Agriculture plays an essential role in to develop any country. Afghanistan depends a lot on agriculture because agricultural reports and statistics show that 80% of the Afghan population work in agriculture and livestock. The contribution of agriculture in Afghanistan’s gross domestic product (GDP) is 31%. We can improve the sector of agriculture with the use of the internet of things based Smart Farming techniques it improves the whole agri-business by keeping an eye on the field in real-time. Sensors has a very vital role in for the interconnectivity and data gathering, IoT device not only provided new techniques for the farmers but it also increased the time-management of the farmers. With the use of the IoT’s now farmers require lesser time on field as IoT powered devices are working for him/her. It reduced the workload of farmers as well as the wastage of many useful resources like water used for irrigation and electricity usage, as it required for the working of so many electrical appliances. IoT devices can easily be used to monitor the real time applications. IoT has the potential to new shape the world so that agriculture will be smart agriculture. We want to control everything from the far way, for example, irrigation, temperature, etc. so we have to use WSN, Wi-Fi or ZigBee modules for controlling the crops. This paper aims to address the use of Internet of Things in the field of agriculture sector.
Interactive comment on “Bioclimatic traits in statistical properties of daily photosynthetically active radiation” by Estefanía Muñoz and Andrés Ochoa

1. Munoz and Ochoa explore patterns of PAR across different latitudes and climate zones. The analysis may be important to the extent that it helps organize and communicate variability in photosynthetically active radiation to the biogeosciences community. At the moment it does not, but I feel that it might. Namely, if the amount of variation in PAR, c, and k explained by solar geometry (obvious) and climate (less obvious) could
Adaptive Gaussian Mixture Model-Based Statistical Feature Extraction for Computer-Aided Diagnosis of Micro-Calcification Clusters in Mammograms

: In mammography, detection and categorization of micro-calciﬁcation clusters (MCCs) using computer-aided diagnosis (CAD) systems are very important tasks because MCCs are important signs at an early stage of breast cancer. However, the conventional methods of CAD only classify MCCs into benign and malignant types, and no method has been developed for a medical requirement to classify the MCCs into more detailed categories according to the spatial distribution of MCCs. To provide a cogent second opinion, we speciﬁcally focus on analyzing MCCs’ spatial distribution and propose an adaptive Gaussian mixture model-based method to extract the statistical features of the spatial distribution in this study. By mimicking the radiologists’ workﬂow, the proposed method used the main feature of each spatial distributions to classify the MCCs and then provide a cogent second opinion to increase the conﬁdence level of diagnosis decisions. The experiments have been performed on 100 mammographic images with MCCs from a clinical dataset. The experimental results showed that the proposed method was able to detect the MCCs and classify the spatial distribution of the MCCs e ﬀ ectively.
Oxidative stress and chorine induced airway dysfunction

The aim of this work was to examine the effects of chlorine (Cl2) gas inhalation on airway dysfunction in a mouse model of irritant-induced asthma. Cl2 inhalation induces airway hyperresponsiveness (AHR), bronchial epithelial cell damage, increased oxidative stress and airway inflammation, characterized by neutrophilia. While the effects of Cl2 inhalation had been previously characterized, mechanisms driving airway injury induced by Cl2 remained elusive. We hypothesized that oxidative stress following Cl2 was pivotally involved in mechanisms leading to airway injury. First, using antioxidants we aimed to further characterize the effects of Cl2 inhalation by evaluating airway mechanics, pulmonary antioxidant activity, lung inflammatory profiles and bronchial epithelial cell proliferation. We established that administration of antioxidants post-Cl2 inhalation was effective at ameliorating AHR, oxidative stress, bronchial epithelial cell proliferation, and airway inflammation, suggesting indirect mechanisms were responsible for Cl2-induced airway damage. Next, we depleted several inflammatory cell types in an attempt to determine which cell type, if any, was contributing to the observed effects of Cl2. We depleted macrophages, eosinophils and neutrophils and found that only depletion of neutrophils was effective at reducing airway hyperresponsivness and prevented endogenous antioxidant activity as measured by nuclear factor (erythroid-derived 2)-like 2 (NRF2) nuclear translocation. Concomitant experiments established Cl2 increased the pro-inflammatory lipid mediators cysteinyl-leukotrienes and mRNA levels of cysLT-related biosynthetic genes. Given the role of cysLTs and their receptor cysLTr1 as established pro-asthma mediators, we chose to explore the role of cysLTr1 in our model by utilizing cysLTr1 deleted mice (cysLTr1-/-). We found that deletion of cysLTr1 worsened measured outcomes following Cl2. Compared to wild-type mice, cysLTr1-/- demonstrated increased AHR, airway neutrophilia and epithelial cell apoptosis. In contrast to wild-type mice, we observed that cysLTr1-/- did not show nuclear translocation of NRF2 or increased antioxidant mRNA levels following Cl2 exposure. At baseline levels, we observed that cysLTr1-/- mice had increased e-cadherin protein expression on bronchial epithelial cells compared to wild-type mice. We propose that deletion of cysLTr1 in mice results in an increased susceptibility to Cl2 induced airway damage and dysfunction and this damage is mediated via an aberrant endogenous antioxidant response. This vulnerability to oxidant damage, likely due to increased neutrophil numbers and NRF2 idleness, may be due to an innate increase in e-cadherin, which is partially mediated via cysLTr1. Finally, we use in vitro studies to examine how exogenous cysteinyl-leukotriene D4 stimulates bronchial epithelial cells to release the neutrophil chemoattractant IL-8. We found this pathway to be dependent on the activation of the epidermal growth factor receptor. These in vitro studies establish…
Mesoscale nanoparticles encapsulated with emodin for targeting antifibrosis in animal models

Abstract The aim of this study is to explore the kidney-targeting capability of mesoscale nanoparticles (MNPs)-emodin (Em-MNPs) and its potential antifibrosis in the animal model. First, MNPs and Em-MNPs were synthesized via nanoprecipitation method, and their diameters were both ∼400 nm with the uniform size. The entrapment efficiency of MNPs was 45.1% when adding emodin at the concentration of 12 mg/mL. Moreover, cytotoxicity assay showed that Em-MNPs presented excellent biocompatibility in rat proximal tubular cells. Cellular uptake assay demonstrated that Em-MNPs had high-efficiency uptake, especially in the cytoplasm. Ex vivo organ fluorescence imaging revealed that Em-MNPs possessed specific kidney-targeting ability with relative long retention time in the kidney (∼24 h). In the renal unilateral ureteral obstruction model, Em-MNPs treatment could significantly alleviate kidney tubule injury and reduce extracellular matrix deposition compared with free MNPs. Herein, Em-MNPs with specific kidney-targeting and preferable antifibrosis effects in animal model may pave an avenue for treating renal diseases.
On Magnetically Coupled Coils Parameter Calculation

Abstract ANSYS Q3D Extractor tool (AQ3DE), using the quasi-static solvers (method of moments, integral equations and FEMs), is very efficient for computing and simulating two- and three-dimensional electromagnetic field. This simulation is used to extract parameters of interest, such as: resistance (R), conductance (G), self-inductance (L), mutual inductance (M) and capacitance (C). These parameters can be further used to optimize and to obtain automatically the design of a wireless power transfer systems (WPTS). The resulting matrices allow the generation of new matrices for any selected parameters. To complete the analysis, the model which is computed will be exported as an equivalent circuit. In this paper, starting from a given WPTS, using AQ3DE tool, the parameters of interest (R, G, L, M, C) were automatically calculated, and the SPICE equivalent circuit was obtained. The analysis was performed for two different distances between the emitter and the receiver. The electrical circuit theory was used for the system analysis of magnetically coupled coil (MCC) system. Starting from the parameters extracted by the AQ3DE tool, the performance of the WPTS has been analysed both in time and frequency domain.
The Role of DOT1L Methyltransferase Activity in Fetal Hematopoiesis

Early mammalian erythropoiesis requires the DOT1L methyltransferase. We demonstrated that loss of DOT1L in mutant mice resulted in lethal anemia during midgestation. The molecular mechanisms by which DOT1L regulates embryonic erythropoiesis have not yet been elucidated. In this study, a methyltransferase mutant mouse line (Dot1L-MM) was generated to determine whether the methyltransferase activity of DOT1L is essential for erythropoiesis. Dot1L-MM mice displayed embryonic lethality between embryonic days 10.5 and 13.5, similar to Dot1lL knockout (Dot1L-KO) mice. However, when examined at E10.5, unlike the Dot1L-KO, Dot1L-MM embryos did not exhibit evidence of anemia. In ex vivo hematopoietic differentiation cultures, Dot1L-KO and Dot1L-MM yolk sac (YS) cells both formed reduced numbers of myeloid, and mixed hematopoietic colonies. Erythroid colonies were able to be formed in numbers equal to wildtype embryos. Extensively self-renewing erythroblast (ESRE) cultures were established using YS cells from E10.5 embryos. Dot1L-KO and Dot1L-MM cells expanded significantly less than wild-type cells and exhibited increased cell death. Strikingly, Dot1L-KO and Dot1L-MM cells of YS origin exhibited profound genomic instability, implicating DOT1L methyltransferase activity in maintenance of the genome as well as viability of hematopoietic progenitors. Our results indicate that the methyltransferase activity of DOT1L plays an important role early murine hematopoiesis.
New Distribution Record of ＂Begonia Grandis＂ (Begoniaceae, Section ＂Diploclinium＂) from Taiwan, with Subspecies Assignment Based on Morphology and Molecular Phylogeny

＂Begonia grandis＂ Dry. (Begoniaceae), previously recognized as endemic to continental China, was recently discovered from southern Taiwan. Close morphological observations and molecular phylogenetic analysis elucidated that the species in Taiwan belongs to subspecies ＂grandis＂. ＂Begonia grandis＂ has a long history in cultivation especially in China and Japan but not in Taiwan. The collection locality in Taiwan had no trace of human activity. Therefore, ＂B. grandis＂ is considered to be native to Taiwan. The new finding in Taiwan marks the southernmost distribution record of the species. Unfortunately, the discovered population was destroyed by a landslide due to a typhoon in 2009. Further field survey in neighboring areas is needed to elucidate the current status of ＂B. grandis＂ in Taiwan.
Investigations of Mechanical Properties of API P110 Steel Casing Tubes Operated in Deep-Sea Sour Condensate Well Conditions

Abstract Due to the complexity of the marine environment, in deep-sea drilling, all kinds of strings are corroded by different deep-sea conditions for a long time, accompanied by high temperature and high pressure, which lead to the continuous change of mechanical properties of materials. In order to solve the problem that the material mechanical parameters cannot be accurately described in the performance analysis of the casing, deep-sea simulated corrosion and material damage experiments of P110 material were carried out in this paper. Mass loss and tensile experiments on corrosion-damaged test pieces were conducted under different corrosion experimental periods. The changes in mechanical properties of the material were analyzed. Equations of the variation of the equivalent yield strength and the equivalent tensile strength were obtained. The results show that the equivalent yield strength and the equivalent tensile strength decrease with the increase of the weight loss rate. Based on the experimental results and finite element analysis, a method for establishing the material corrosion model was proposed in this paper. The deep-sea drilling corrosion performance model of P110 material was established, which greatly reduced the error caused by the material uniformity assumption in finite element analysis. This paper provides a theoretical basis for the analysis of reliability and life of P110 materials in wells.
Cultural Rights, Well-being and Democracy in Elderly Care: The Dance Ambassadors as a Case Study

Abstract The aim of this article is to introduce how the Dance Ambassadors are perceived by nursing staff and supervisors in institutions of elderly care. The Dance Ambassadors are a dance-based service concept offered in various social contexts by the Dance Centre of Western Finland. Three central themes were identified in the perspectives of nursing staff: dance as a form of rehabilitation and support, dance as a contribution to a meaningful life, and participation in dance as a basic right. In the research, a multi-sited dance ethnographic approach was adopted to collect data. Then a thematic analysis was conducted in tandem with a descriptive-interpretative mixed methods approach to code and interpret the data. Social and theoretical frames as well as key concepts including cultural rights and cultural well-being are introduced in the article. In the discussion, some critical concerns are highlighted regarding the rehabilitation discourse in relation to dance in elderly care contexts and the unequal access to dance for people in late adulthood, which stands in stark contrast to the Constitution and its emphasis on human rights and equal treatment. Some suggestions are provided to improve the situation.
Left Ventricular Function and Morphology after Cardiac Surgery for Severe Mitral Insufficiency - A Single Center Experience

Abstract Introduction: Mitral insufficiency is a common valvular disease affecting 10% of the general population. The main treatment of the severe mitral regurgitation is surgical. We have analyzed the impact of cardiac surgery on the left ventricular performance and morphology, in patients treated for severe mitral insufficiency accordingly to the type of intervention, ischemic time and type of cardioplegia. Methods: Ninety patients diagnosed with isolated severe mitral insufficiency that benefited from mitral valvular replacement or mitral valvuloplasty were retrospectively enrolled. The left ventricle, the left atrium, the right ventricle diameters and the left ventricle ejection fraction were measured by two-dimensional (2D) echocardiography before and after surgery. The influence of the myocardial ischemia time and the type of cardioplegia administered on the ventricular systolic function were also analyzed. Results: Regardless the surgical technique chosen, after surgery we noticed a decreased size of the left ventricle (preoperative mean 54.91mm ±8.18 vs postoperative mean 51.94mm±8.15, p=0.035), right ventricle (preoperative mean 33.49mm±5,87 vs postoperative mean 32.41mm±6.03, p=0.0001), as well as the ejection fraction (preoperative mean 51.29%±8.51 vs postoperative mean 46.57%±8.71, p=0.0001). Conclusions: Immediately after surgery, a decrease in the size of cardiac cavities as well as a decrease of the left ventricle ejection fraction is noticed.
Structure and some physicochemical and functional properties of water treated under ammonia with low-temperature low-pressure glow plasma of low frequency

Abstract Deionized, tap and two kinds of commercially available mineralized water, after supplementation with ammonia, were treated with low-pressure, low-temperature glow plasma (GP) of low frequency. Treating hard water with ammonia provided the removal of permanent and temporary water hardness already at room temperature. On such treatment, mineralized water supplemented with ammonia was partly demineralized. Precipitated rhombohedral deposit from hard water did not turn into scale even when maintained in suspension for 3 days at around 90°C. In such manner, the use of other chemicals for prevention from the scale formation and/or for the scale removal is entirely dispensable. The rate and yield of precipitation depended on the concentration of admixed ammonia and the GP treatment time. Ammonia served as a ligand of calcium, magnesium and ferric central atoms of corresponding salts constituting the hardness. Moreover, ammonia constituting the atmosphere of the treatment was arrested inside aqueous clathrates. So, stabilized ammonia solutions could potentially be utilized as an environmental-friendly nitrogen fertilizer. The precipitate could also be utilized for the same purpose.
Classification of High Resolution Satellite Images Using Improved U–Net

Abstract Satellite image classification is essential for many socio-economic and environmental applications of geographic information systems, including urban and regional planning, conservation and management of natural resources, etc. In this paper, we propose a deep learning architecture to perform the pixel-level understanding of high spatial resolution satellite images and apply it to image classification tasks. Specifically, we augment the spatial pyramid pooling module with image-level features encoding the global context, and integrate it into the U-Net structure. The proposed model solves the problem consisting in the fact that U-Net tends to lose object boundaries after multiple pooling operations. In our experiments, two public datasets are used to assess the performance of the proposed model. Comparison with the results from the published algorithms demonstrates the effectiveness of our approach.