Miracle-dz/UniFAR-FTUs huggingface dataset:
A case report of visual outcome in keratoconus with retinitis pigmentosa

Background: It is uncommon to see retinitis pigmentosa in keratoconus patients. The main difficulty of visual rehabilitation for this is restricted visual field. We presented the treatment and gene screen of visual system homeobox 1 (VSX 1) gene in this case. Case presentation: A 24-year-old man with retinitis pigmentosa presented with progressively blurred vision. Slit lamp examination revealed Vogt’s striae over both eyes, and corneal topography indicated bilateral keratoconus. We had tested 5 exons of VSX 1 gene from him and the did not find mutation on direct sequence. To improve visual acuity, we prescribed keratoconus rigid gas permeable (RGP) contact lens for him with good efficacy. However, lens dislocation occurred occasionally. He could not find dislocated lens easily due to visual field restriction, so he asked for more stable visual aids. Therefore, we instead prescribed scleral lens (SL), which were more stable on the ocular surface and led to more stable vision. Visual acuity was also gained with SL, but the tolerance time for SL was shorter compared to that of keratoconus RGP contact lens. To compare the efficacy of these two lenses, we surveyed life quality using the National Eye Institute Visual Functioning Questionnaire – 25 in three situations: baseline, with keratoconus RGP contact lens, and with SL. Conclusion: The patient used the two lens types according to his needs, and benefited from vision rehabilitation with both keratoconus RGP contact lens and SL. Keywords: keratoconus; retinitis pigmentosa; rigid gas permeable contact lenses; scleral lenses.
Ruminococcus gnavus, an unusual cause of surgical site infection following vertebral posterior instrumentation: a case report

Background Ruminococcus gnavus (R. Gnavus) is an anaerobic Gram-positive coccus, common commensal of the gastrointestinal tract of animals and humans. Anaerobic organisms as etiologic agents of bone and joint infections (BJI) are uncommon and frequently underestimated. New technologies, such as mass spectrometry techniques and molecular techniques like 16S rRNA, allow for more efficient diagnosis of these anaerobic bacteria. We present the first case report of deep surgical site infection (SSI) due to R. Gnavus, following spinal surgery. Case Description We report the case of a deep SSI caused by R. Gnavus following posterior spinal instrumentation in an 81-year-old woman. The patient underwent extension of her previous fusion L2-L5, due to adjacent segment disease (ASD). We performed a T10 to S2-alar-iliac instrumentation. During the postoperative period, the patient presented with a paralytic ileus that required the placement of a nasogastric tube followed by gastrointestinal bleeding and two gastroscopies. Subsequently the patient showed signs of deep SSI. We performed surgical irrigation and debridement. All six cultures in anaerobic media showed short Gram-positive diplococci, using matrix-assisted laser desorption/ionization time of flight mass spectrometry (Maldi-TOF MS) all six strains were identified as R. Gnavus. The patient was treated with amoxicilin 1 g/8 h and ciprofloxacin 750 mg/12 h for 4 weeks. Six months postoperative, she was asymptomatic. Conclusions As is the case with our patient, all previously described cases of R. Gnavus infection had a history of intestinal disease or immunosupression. We believe the isolation of R. Gnavus should raise the possibility of intestinal injury. Immunosuppression is also an important risk factor for the development of R. Gnavus infection.
LOADING AND RELEASE OF LARGE PROTEIN MOLECULES AND SEPARATION OF LANTHANIDES USING MESOPOROUS MATERIALS

iii LIST OF FIGURES AND SCHEMES . ix ACKNOWLEDGMENTS . xiv CHAPTER 1 GENERAL INTRODUCTION . 1 CHAPTER 2 CONTROLLED RELEASE AND INTRACELLULAR PROTEIN DELIVERY FROM MESOPOROUS SILICA NANOPARTICLES . 3 2.1 Abstract . 3 2.2 Introduction . 4 2.3 Mesoporous silica nanoparticles: Ideal candidates for protein delivery . 5 2.4 Tuning the pore size, shape, and surface of MSNs . 7 2.5 Pore expanding agents . 9 2.6 Non-surfactant templates . 11 2.7 Non-spherical morphologies . 12 2.8 Surface functionalization of MSNs with stimuli-responsive tethers . 14 2.9 Magnetic and thermal stimuli responsive systems . 15 2.10 Photosensitive-responsive systems . 16 2.11 pH sensitive systems . 16 2.12 Biolistic Method . 18 2.13 Applications . 19
High-efficiency purification desulfurizer for high-acid oil and gas

本发明属石油天然气净化技术领域，涉及一种从高酸性石油天然气中高效净化脱除酸性组分的脱硫剂。 含有10～85%(wt)的醇胺化合物、15～75%(wt)的含氧和/或氮杂环化合物A、0.1～30%(wt)的含氧和/或氮杂环化合物B、0.1～30%(wt)的含硫杂环化合物、以及10～80%(wt)的水。 采用本发明脱硫剂，能够将高酸性石油天然气中的有机硫、H2S和CO2分别由约1000mg/Nm3、约15%(mol)和约9%(mol)降至20mg/Nm3以下、5mg/Nm3以下和0.1%(mol)以下，有机硫脱除率最高可达98%以上。 原料高酸性石油天然气的压力可在0.1MPa至8. 5MPa。 与普通醇胺溶剂相比，本发明脱硫剂具有脱硫率高、稳定性好、再生能耗低、跑损少、起泡少等显著优点，对于高硫含量、特别是高有机硫含量石油天然气的净化具有明显效用。
A Single Robust Hydrogel Film Based Integrated Flexible Supercapacitor

Integrated configuration can greatly improve the stability of an energy-storage device in a large or repeated mechanical deformation process, but there is little attention paid to develop this conceptual energy-storage device. Here, we successfully design two embedded polypyrrole (PPy) layers as electrodes and a boron cross-linked PVA(poly(vinyl alcohol))/KCl hydrogel film as electrolyte to construct an integrated electrode–electrolyte–electrode flexible supercapacitor (so-called all-in-one supercapacitor). The boron cross-linked PVA/KCl hydrogel film (B-PVA/KCl) is prepared by simple physical and chemical cross-linking methods. Then, the conducting PPy is embedded in the B-PVA/KCl film by in situ growth to form a PPy/B-PVA/KCl composite film, which shows superior toughness and strength when it undergo large deformations, such as stretch, twist and compression. The integrated flexible supercapacitor can obtain a large areal capacitance of 224 mF cm–2 and a remarkable energy density of 20 μWh cm–2. Further.
Design, synthesis and biological evaluation of P2-modified proline analogues targeting the HtrA serine protease in Chlamydia.

High temperature requirement A (HtrA) serine proteases have emerged as a novel class of antibacterial target, which are crucial in protein quality control and are involved in the pathogenesis of a wide array of bacterial infections. Previously, we demonstrated that HtrA in Chlamydia is essential for bacterial survival, replication and virulence. Here, we report a new series of proline (P2)-modified inhibitors of Chlamydia trachomatis HtrA (CtHtrA) developed by proline ring expansion and Cγ-substitutions. The structure-based drug optimization process was guided by molecular modelling and in vitro pharmacological evaluation of inhibitory potency, selectivity and cytotoxicity. Compound 25 from the first-generation 4-substituted proline analogues increased antiCtHtrA potency and selectivity over human neutrophil elastase (HNE) by approximately 6- and 12-fold, respectively, relative to the peptidic lead compound 1. Based on this compound, second-generation substituted proline residues containing 1,2,3-triazole moieties were synthesized by regioselective azide-alkyne click chemistry. Compound 49 demonstrated significantly improved antichlamydial activity in whole cell assays, diminishing the bacterial infectious progeny below the detection limit at the lowest dose tested. Compound 49 resulted in approximately 9- and 22-fold improvement in the inhibitory potency and selectivity relative to 1, respectively. To date, compound 49 is the most potent HtrA inhibitor developed against Chlamydia spp.
IRRIGATION WATER MANAGEMENT OF WHEAT CROP UNDER SOWING DATES AT FAYOUM

A field experiment was conducted at Kom Osheem Agric. , Res., Station, Fayoum, Egypt during 2003/2004 and 2004/2005 seasons to study the effect of three sowing dates, i.e. D1: 22 Nov., D2: 2 Dec., and D3:12 Dec. and irrigation water managements, i.e. irrigation at I1:30%, I2:55% and I3 : 80% available soil moisture depletion (ASMD) on yield, yield components and some water relations of wheat crop (Giza 168 cv.). A split-plot design with four replications was used in both seasons. The main obtained results were as follows: 1. Planting wheat on 22 Nov., and irrigation at 30% ASMD gave the highest averages of plant height, spike number/m 2 , grain weight/ – grain weight, grain yield/fed. (1566.0 and 1656.0 kg), and straw yield (3625.9 and 3824.4 kg/fed.) in the two successive seasons. The lowest averages of yield and its components were obtained from sowing on 12 Dec. and irrigation at 80% ASMD in both seasons. 2. Delaying sowing date from 22 Nov. to 12 Dec., significantly decreased all yield components, grain yield/fed by 12.7% and 12.4% and straw yield/fed by 24.7% and 25.6% in 2003/2004 and 2004/2005 seasons, respectively. However, increasing the ASMD from 30% to 80% significantly decreased yield components, grain yield/fed by 29.7% and 24.5%and straw yield/fed by 11.9% and 13.4% in the two successive seasons. 3. Seasonal consumptive use (ETc), as a function of the different treatments averaged 40.40 and 39.70 cm in 2003/2004 and 2004/2005 seasons, respectively. Delaying sowing date from 22 Nov. to 12 Dec., and increasing ASMD from 30% to 80% decreased seasonal Etc from 46.18 and 45.43 cm to 35.35 and 34.85 cm in the two successive seasons. 4. Daily ETc rates were low during Nov. and Dec., then increased during Jan. and Feb., to reach its maximum values during March and declined again at April till harvesting. The values of daily ETc decreased with delaying sowing date than 22 Nov. and increasing ASMD than 30% in the two growing seasons months. The crop coefficient (Kc) values were 0.51, 0.59, 0.67, 0.80, 0.95, 0.69 and 0.49 (averages of the two seasons) for, Nov., Dec., Jan., Feb., Mar., Apr. and May, respectively. 5. The highest water use efficiency values were 0.871 and 0.936 kg grains/m 3 water consumed were obtained from D3I2 treatment in 2003/2004 season and D2I2 treatment in 2004/2005 season, respectively.
Peptide‐Gold Nanoparticle Conjugates as Sequential Cascade Catalysts

Combining bio‐ and chemocatalysis in one pot is a challenging task due to the necessity to ensure compatible reaction conditions, as well as reagent tolerance, for the catalytic components. Here we present a peptide‐gold nanoparticle conjugate that combines esterase (biocatalysis) and hydrogenation (chemocatalysis) activities under the same set of aqueous reaction conditions. The self‐assembled peptide‐monolayer acts as an esterase mimic and shows positive cooperativity in substrate binding, an important feature used by nature to regulate catalytic activities of enzymes. The gold nanoparticle surface catalyzes the reduction of a nitro‐containing substrate to an amine product. This study opens up a new avenue in the design of peptide‐metal nanoparticle catalysts with enzyme‐like properties for efficient one‐pot reactions.
Hierarchical hollow, sea-urchin-like and porous Ni0.5Co0.5Se2 as advanced battery material for hybrid supercapacitors

Hierarchical Ni0.5Co0. 5Se2 containing a hollow inner structure, with a 3D sea-urchin-like overall morphology and very porous nanowires, was first synthesized by a low-temperature selenization method. Benefiting from such a hierarchical structure, the Ni0.5Co0. 5Se2 demonstrates a much improved specific area to provide more electroactive sites and a self-supporting 3D structure to make good contact with the electrolyte. More significantly, it is found that the bimetal Ni0.5Co0. 5Se2 combines electrochemical advantages from both Ni and Co, showing high electroactivity and low charge transfer resistance. As a result, the hierarchical Ni0.5Co0. 5Se2 exhibits a higher specific capacity of 524 C g−1 at 1 A g−1, a superior rate performance of 56% capacity retention when the specific current increases by 50 times and excellent cycling stability of 91% capacity retention after 3500 cycles. In addition, an Ni0.5Co0. 5Se2//reduced graphene oxide (RGO) HSC achieves a high specific energy of 37.5 W h kg−1, an ultrahigh specific power of 22.2 kW kg−1 and an outstanding cycling stability up to 10 000 cycles, further confirming the superior performance of hierarchical Ni0.5Co0. 5Se2.
IoT-based Cloud Service for Secured Android Markets using PDG-based Deep Learning Classification

Software piracy is an act of illegal stealing and distributing commercial software either for revenue or identify theft. Pirated applications on Android app stores are harming developers and their users by clone scammers. The scammers usually generate pirated versions of the same applications and publish them in different open-source app stores. There is no centralized system between these app stores to prevent scammers from publishing pirated applications. As most of the app stores are hosted on cloud storage, therefore a cloud-based interaction system can prevent scammers from publishing pirated applications. In this paper, we proposed IoT-based cloud architecture for clone detection using program dependency analysis. First, the newly submitted APK and possible original files are selected from app stores. The APK Extractor and JDEX decompiler extract APK and DEX files for Java source code analysis. The dependency graphs of Java files are generated to extract a set of weighted features. The Stacked-Long Short-Term Memory (S-LSTM) deep learning model is designed to predict possible clones. Experimental results have shown that the proposed approach can achieve an average accuracy of 95.48% among clones from different application stores.
Impacts of meteorology and emissions on summertime surface ozone increases over central eastern China between 2003 and 2015

Abstract. Recent studies have shown that surface ozone (O3) concentrations over central eastern China (CEC) have increased significantly during the past decade. We quantified the effects of changes in meteorological conditions and O3 precursor emissions on surface O3 levels over CEC between July 2003 and July 2015 using the GEOS-Chem model. The simulated monthly mean maximum daily 8 h average O3 concentration (MDA8 O3) in July increased by approximately 13.6 %, from 65.5±7.9 ppbv (2003) to 74.4±8.7 ppbv (2015), comparable to the observed results. The change in meteorology led to an increase in MDA8 O3 of 5.8±3.9 ppbv over the central part of CEC, in contrast to a decrease of about -0.8±3.5 ppbv over the eastern part of the region. In comparison, the MDA8 O3 over the central and eastern parts of CEC increased by 3.5±1.4 and 5.6±1.8 ppbv due to the increased emissions. The increase in averaged O3 in the CEC region resulting from the emission increase (4.0±1.9 ppbv) was higher than that caused by meteorological changes (3.1±4.9 ppbv) relative to the 2003 standard simulation, while the regions with larger O3 increases showed a higher sensitivity to meteorological conditions than to emission changes. Sensitivity tests indicate that increased levels of anthropogenic non-methane volatile organic compounds (NMVOCs) dominate the O3 increase over the eastern part of CEC, and anthropogenic nitrogen oxides (NOx) mainly increase MDA8 O3 over the central and western parts and decrease O3 in a few urban areas in the eastern part. Budget analysis showed that net photochemical production and meteorological conditions (transport in particular) are two important factors that influence O3 levels over the CEC. The results of this study suggest a need to further assess the effectiveness of control strategies for O3 pollution in the context of regional meteorology and anthropogenic emission changes.
Deteksi Cepat Fusarium sp. pada Benih Kedelai Menggunakan Metode Spektroskopi Fluoresens

Rapid Detection Method for Fusarium sp. on Soybean Seed Using Fluorescence Spectroscopy MethodSeed borne pathogens play an important role as source of inoculum for disease in the field. Seed health testing is applied in order to prevent risks caused by seed borne pathogen. Fluorescence spectroscopy is a potential technology to be used as detection method for seed borne pathogen. Research was conducted to develop rapid detection protocol for seed borne pathogenic fungus by fluorescence spectroscopy method. The result showed that fluorescence spectroscopy could detect fluorescence emission of metabolite of Fusarium sp. after soybean seeds were incubated for 24 hr. Metabolite of Fusarium sp. produced cyan fluorescent at peak wavelength emission 504 nm when excited to violet light (405 nm). Fusarium sp. displayed typical fluorescence emission spectra which differ from fluorescence emission spectra of growth medium potato dextrose broth (PDB) (502 nm). It was evidenced that fluorescence spectroscopy method can be used to detect pathogenic seed borne fungi.
Organisational Support in Knowledge Transfer Activities towards ERP Success: Scale Development and Validation

The successes of ERP system in an organization depend on knowledge transfer activities being made and the effectiveness of the transferred knowledge between the parties involved. It is important to determine a set of knowledge transfer activities that need to be done besides efforts undertaken by the organisation in ensuring ERP success. Currently, there is still lacking of standard knowledge transfer measurement and organisational support that impacted ERP system. Previous research has reported various factor impacted the transfer of knowledge in strategic alliances and joint venture. Nonetheless, organisational support is the least factor mentioned especially studies from Malaysia. Addresses this gap, the main purpose of this study is to develop a validated scale of organisational support in supporting knowledge transfer activities towards ERP system success. The study has adapted six stages of scale development and validation of measurement items according to legitimate measures. The measurement scales formed are based on literature review and field studies conducted to increase the reliability and validity values. Organisational support constructs were divided into Top Management Support, Communication and User Training and Education. Total of 16 items have been successfully established for further validation.
Solubility of ammonium paratungstate in aqueous diammonium phosphate and ammonia solution and its implications for a scheelite leaching process

ABSTRACT Scheelite could be digested with an aqueous diammonium phosphate and ammonia solution in an autoclave. However, unexpected ammonium paratungstate (APT) crystallisation and tungstophosphoric acid formation occasionally occurred. In order to provide a theoretical basis for the scheelite leaching process, the solubility of APT in solution was determined by the isothermal solution equilibrium method. The effects of initial ammonia and diammonium phosphate concentration as well as temperature on APT solubility and tungstophosphoric acid formation were investigated. Results showed that APT solubility increased with increasing ammonia concentration, diammonium phosphate concentration and temperature, while tungstophosphoric acid concentration in the leaching solution increased with decreasing ammonia concentration and increasing diammonium phosphate concentration. In order to verify the effects of these factors on the leaching of scheelite, scheelite digestion experiments using diammonium phosphate and ammonia solution were also carried out.
Anisotropic lateral oxidation of Al-III–V semiconductors: inverse problem and circular aperture fabrication

The lateral wet oxidation of aluminum-containing III–V-semiconductors is a technological process which converts a buried (thin) cristalline material into an amorphous insulator and, as such, tends to exhibit an anisotropic behavior. As a result, the shape of the interface between the semiconductor and the insulator, often referred as the oxide aperture, differs from the etched mesa contour from which the oxidation proceeds. This, in turn, complicates the design of the devices relying on this process especially when specific oxide patterns are needed. In this paper, we introduce a method based on a morphological dilatation to determine the shape of the mesas which will lead to a specific targetted contour upon an anisotropic oxidation over a modest extent. The approach is experimentally validated by demonstrating the fabrication of circular oxide apertures which are inherently difficult to make because of their high degree of symmetry but which also turn out to be of critical importance in obtaining efficient single-mode vertical-cavity surface-emittting lasers.
Kinetics and Ensemble Dynamics of Colloidal Ellipsoids near an AC Electrode

The manipulation of colloidal particles via applying electric fields has been studied over the past 30 years due to the unique properties associated with the fabricated colloidal crystals. Most works in this field focused on utilizing an alternating current (AC) electric field with spherical particles. However, utilizing spherical colloidal particles as building blocks for complex microstructures has been challenging. Consequently, more recent work has shifted to employing complex colloids (anisotropic in nature) as building blocks for advanced materials. In our work, the phase diagram and the kinetics of assembling colloidal polystyrene ellipsoids under an AC electric field at low frequencies were studied. Specifically, the structure of colloidal ellipsoid ensembles under varying electric field potentials (0.5 V, 1.0 V, and 1.5 V) was measured at a periodically regulated frequency (30 Hz ~ 3000 Hz) and the same set of experiments was done for colloidal spheres as a comparable reference. Data suggested the approximate critical frequency for assembled particles depended on the aspect ratio and the inherent block anisotropy may impact the mesoscale structure. Additionally, the rate constant for the rapid aggregation of colloidal particles was calculated via the plot of singlet evolution at varying electric field conditions. Results showed an increase in applied potential and a larger aspect ratio for the colloidal ellipsoids both resulted in a larger rate constant.
Study of Nitrogen and Phosphorus transformations in cement ponds of Nile tilapia fry.

The ever-expanding of aquaculture activities raised concerns about the unknown detrimental effects of high effluent loading on the aquatic ecosystems. Therefore, this study quantified the accumulation of nitrogen (N) and phosphorus (P) in different forms in the water, sludge and fry in rearing ponds. Four ponds were assigned in a Nile tilapia hatchery of private sector to study the nutrient mass balance and the chemical composition of the sludge, in two fry production cycles, each for 25 days divided into three periods, during April-June 2021. The results showed that, every Kg feed (45% protein) produces 420 g sludge and 355.94 g suspended solids, 50% out of which settled at the bottom. Fry retained 27.6 % and 20.4 % of the applied dietary nitrogen and phosphorus, respectively. Accumulation of TN and TP in the sludge accounted for 16.6% of the dietary N and 50% of the dietary P. Effluent water contained 29.16 % and 25.8 % of introduced dietary nitrogen and phosphorus, respectively, distributed in different forms. The dietary nitrogen recovery in the present study was 73.38%, suggesting considerable role for ammonia volatilization, denitrification and anammox processes in the N-losing and almost no N-fixation occur in these ponds, while the phosphorus recovery reached 96%. The results also showed that the fry rearing ponds threaten Egyptian Journal for Aquaculture P-ISSN: 2090-7877 E-ISSN: 2636-3984 www.eja. journals.ekb. eg/ Moustafa et al., 2021; 11 (1):334 5 DOI: 10.21608/eja.2021. 90477.1057 Study of Nitrogen and Phosphorus transformations in cement ponds of Nile tilapia fry 34 the environment, as their effluent and sludge are rich in nutrients. Thus, it is recommended to utilize the fry ponds effluent in microalgae production and recycle the sludge into vermicompost fertilizer.