Miracle-dz/UniFAR-FTUs huggingface dataset:
Ergonomics Design and Assistance Strategy of A-Suit

Concerning the biomechanics and energy consumption of the lower limbs, a soft exoskeleton for the powered plantar flexion of the ankle, named A-Suit, was developed to improve walking endurance in the lower limbs and reduce metabolic consumption. The method of ergonomics design was used based on the biological structures of the lower limbs. A profile of auxiliary forces was constructed according to the biological force of the Achilles tendon, and an iterative learning control was applied to shadow this auxiliary profile by iteratively modifying the traction displacements of drive units. During the evaluation of the performance experiments, four subjects wore the A-Suit and walked on a treadmill at different speeds and over different inclines. Average heart rate was taken as the evaluation index of metabolic consumption. When subjects walked at a moderate speed of 1.25 m/s, the average heart rate Hav under the Power-ON condition was 7.25 ± 1.32% (mean ± SEM) and 14.40 ± 2.63% less than the condition of No-suit and Power-OFF. Meanwhile, the additional mass of A-Suit led to a maximum Hav increase of 7.83 ± 1.44%. The overall reduction in Hav with Power-ON over the different inclines was 6.93 ± 1.84% and 13.4 ± 1.93% compared with that of the No-Suit and Power-OFF condition. This analysis offers interesting insights into the viability of using this technology for human augmentation and assistance for medical and other purposes.
Large-Scale Analysis of Circulating Amino Acids and Adipose Gene Expression in Relation to Abdominal Obesity

1 Background: Circulating level of the amino acid glutamate is associated with central fat 2 accumulation, yet the pathophysiology of this relationship remains unknown. We aimed to: i) 3 refine and validate the association between circulating glutamate and abdominal obesity in a 4 large population-based twin cohort; and ii) investigate whether transcriptomic profiles in adipose 5 tissue could provide insight into biological mechanisms underlying the association. Methods: 6 First, in a cohort of 4,665 individuals from the TwinsUK resource, we identified individuals with 7 abdominal obesity and compared prevalence of the latter across circulating glutamate quintiles. 8 Second, we used transcriptomic signatures generated from adipose tissue, both subcutaneous and 9 visceral, to investigate associations with circulating glutamate levels. Results: Individuals in the 10 top circulating glutamate quintile had a 7-fold higher prevalence of abdominal obesity compared 11 to those in the bottom quintile. The adipose tissue transcriptomic analyses identified GLUL , 12 encoding Glutamate-Ammonia Ligase, as being associated with circulating glutamate and 13 abdominal obesity, with pronounced signatures in the visceral depot. Conclusion: Circulating 14 glutamate is positively associated with the prevalence of abdominal obesity which relates to 15 dysregulated GLUL expression specifically in visceral adipose tissue. 16
Distinguishing Emerald Ash Borer from Native Borers

Emerald ash borer (Agrilus planipennis, EAB) is not the only wood-boring insect that attacks ash trees. Several native clearwing and roundheaded borers also commonly infest ash. That’s why the ability to distinguish EAB infestations from those of native borers is extremely important. Indeed, virtually every declining or dead ash tree will be at some point colonized by native borers, which attack weak, dying, and freshly killed trees.
Modelling transdisciplinary pedagogy: A method for collaborative curriculum design

This article explores a transdisciplinary, collaborative, curriculum design project to promote institutional belonging as a driver of student engagement, and to equip graduates with the fluency to work across disciplines. It demonstrates a facilitated method, to construct learning outcomes that break with typical subject-based knowledge and associated hierarchies of expertise. After considering a small number of precedents, the authors use curriculum models to inform a design specification. Following the formation of a multidisciplinary design team, a development tool (Lego® Serious Play®) was selected for a design workshop. A qualitative analysis of the workshop transcript was then used to inform the learning outcomes for a common module to be taken by all first-year undergraduates. Finally, the article considers how the process provided a framework for collaborative design that has been implemented in further projects, and led to the creation of a growing community of practice. The project provides insights for others embarking on collaborative curriculum design initiatives, especially where transdisciplinary learning is an objective.
The Role of External Mechanisms and Transformational Leadership in Information Security Policy Effectiveness: A Managerial Perspective of Financial Industry in Vietnam

Information security policy (ISP) violations are one of the biggest concerns for all organisations around the world, resulting in billions of direct and indirect losses; especially in the financial industry. Senior managers and their leadership style play a crucial role in enforcing the employees’ compliance with ISP. However, previous research has been mostly conducted at individual level and has not fully investigated the effectiveness of ISP from managerial and organisational perspectives. Drawing on neo-institutional theory and transformational leadership model, this research investigates the impact of external mechanisms and transformational leadership on the effectiveness of ISP. The proposed research model will be tested using field survey data from professional managers in the financial sector. Partial least square structural equation modelling (PLS-SEM) will be used to test the proposed hypotheses. The potential contribution of this study is to enhance our knowledge from a theoretical and practical perspective of the role of external and transformational leadership in the effectiveness of ISP.
Educational Process Mining based on Moodle courses: a review Educational Process Mining based on Moodle courses: a review of literature of literature

With the prevalence of E-Learning, it is important to analyze how students progress in this environment. These systems collect data about the students’ learning path, and Process Mining (PM) can provide a detailed model of this path. Based on the analysis of ten Educational Process Mining (EPM) case studies involving Moodle event logs, this article aims to contribute a literature review on EPM’s research. Beyond a theoretical introduction to PM and its implications for educational data, the review concludes on what PM tools and techniques are used, as well as the challenges faced in practice. The technical options include software, process discovery algorithms and representation models. These results aim to create a list of available options for future EPM endeavors, in addition to a list of issues to consider in future research involving Moodle.
Framework of emergence: from chain of value to value constellation

ABSTRACT For academic design programmes and research councils, finding mechanisms to measure impact and valuate co-design research projects is very difficult. The metric parameters – number of attendees, volume, shape, length – have shown to be insufficient. The subject matter, the subjects and matters, do not easily fit within these parameters, which fail to translate the value of a ‘constellation of affections’ that emerge throughout co-design processes. Emphasis on quantifiable impact derives from particular ways of understanding production, reproduction, and dissemination of knowledge. This paper understands academic design programmes as a technology to discuss axiology in co-design practices. This paper re-configures a techno-logic of value; from chain of value to value constellation, intersecting a co-design case study with readings of Simondon’s philosophy of technology and Barad’s agential realism. Ageing Playfully was a knowledge exchange project from The Creative Exchange programme, that involved people living with dementia and their caregivers co-designing interventions to boost mobility and well-being. At the core, this paper, explores an axiological move that informs a framework of emergence, a way of thinking in methods to account for the value of co-design as site of emergence.
Comparison of Robustness between Linear Regression and Logistic Regression in Dichotomous Criterion

As \Big data" has arisen, simplicity and robustness for analysis have been emphasized. Therefore, we focus on the model which is relatively simpler and more robustness against (cid:13)uctuation of data. Accurate classi(cid:12)cation is one of the most important things to decide a model for decision making in practice. Logistic model is known as an accurate model to estimate the probabilities of dependent categories. However, focusing on the goal of classi(cid:12)cation in practical use, we assume that linear regression can be more eﬃcient in using practical decision making. We start this study to identify the linear regression analysis is better in robustness than the logistic regression analysis. In simulation, by increasing the number of independent variables, we observe the performances of each method. We try diverse data generated by diﬀerent models to see the robustness of linear regression analysis. Based on the two conjectures, we analyze the prediction errors of each method. By comparing prediction errors, we conclude the linear regression analysis is the most robust method in our simulation. However, because wee only simulate the equal proportioned two classes, the further study is needed.
Implementation Educational Data Mining For Analysis of Student Performance Prediction with Comparison of K-Nearest Neighbor Data Mining Method and Decision Tree C4.5

Data Mining is very useful and widely applied in various fields, one of which is in the field of education. Data mining can be applied to the field of Educational institutions and is also often referred to as Educational Data Mining (EDM). Colleges currently compete with each other to improve the quality of their education for the creation of competent and high-integrity human resources. The amount of data contained in Higher Education can be utilized for the need for useful information so that the data attributes can be known so that the data is analyzed to improve student performance and achievement. And also the results of the analysis are expected to be able to anticipate the problem of delays in the study period that is often experienced by students. In this study conducted using two algorithm models namely K-Nearest Neighbor and Decision Tree C4.5. The best accuracy value is the K-Nearest Neighbor algorithm model with an accuracy rate of 59.32%, whereas in the Decision Tree C4.5 model the accuracy rate is 54.80%, the application of EDM and is expected to be maximized and developed so that it can contribute and develop in education world especially in data mining
Effect of home-based pulmonary rehabilitation using a woven rubber chain on the quality of life of COPD patients in Chiang Dao district, Chiang Mai, Thailand

Objective To determine the eff ectiveness of using a woven chain of rubber bands as an exercise device in home-based pulmonary rehabilitation (HBPR) in improving exercise capacity (6MWD), health-related quality of life (HRQoL) and prognosis (BODE index) in COPD patients. Methods An 8-week randomized controlled trial (RCT) single blind (assessor blind) study was conducted with 30 COPD patients, 15 in the intervention group and 15 in the control group. All patients participating in the HBPR program were pre and post evaluated for lung function via spirometry, exercise capacity via 6MWD, HRQoL via SGRQ, and prognosis via BODE index. All scores were compared using the Paired t-Test within groups and the Independent t-Test between groups. Statistical signifi cance was set at p <0.05. Results Exercise using a woven chain of rubber bands for HBPR therapy improved exercise capacity (6MWD) by 26.67±39.20 meters ( p <0.01), SGRQ score (impact domain) by -19.41±14.13 points ( p <0.04) and BODE index score by -0.06±16.68 points ( p <0.03) compared to the control group in which both 6MWD and BODE index declined. and disease prognosis (BODE index) in COPD patients. Th e model regime used in this study is practical and is likely to be complied with. HBPR using a woven chain of rubber bands is easy to access and helps eliminate the need to travel to an exercise facility. Long-term results and potential problems still need to be closely monitored. Chiang Mai Medical Journal 2019;58(1):3-13.
DDDT_A_270829 4029..4051

*These authors contributed equally to this work Abstract: Denosumab is a receptor activator of nuclear factor kappa-Β ligand inhibitor, which suppresses the bone resorption process to preserve bone mass. It is usually recommended to postmenopausal women and men with high fracture risk. With the recent publication of the results from FREEDOM study and its extension, the long-term effect of denosumab in preventing fragility fractures has been put forward. This review aims at summarising the evidence of denosumab in reducing fracture risk and its safety derived from clinical studies. Most of the evidence are derived from FREEDOM trials up to 10 years of exposure. Denosumab is reported to prevent vertebral and non-vertebral fractures. It is also proven effective in Japanese women, patients with chronic kidney diseases and breast cancer patients receiving antineoplastic therapy. Denosumab discontinuation leads to high remodeling, loss of bone mineral density and increased fracture risk. These negative effects might be preventable by bisphosphonate treatment. The safety profile of denosumab is consistent with increased years of exposure. In conclusion, denosumab is a safe and effective option for reducing fracture risk among patients with osteoporosis.
APPLICATION OF AN ELLIPSOIDAL HEART MODEL IN STUDYING LEFT VENTRICULAR

A geometrical model for the left ventricle is developed consisting of a nested set of truncated ellipsoidal shells of revolution. The geometrical parameters are modelled with the aid of measuring data and assumptions about ventricular deformation. The shells contain muscle fibres which gmerate wall tension (according to a muscle model previously described), from which ventricular pressure results. Fibre length and orientation have different values per shell. After ventricular deformation (change in preload, ejection) new values of the length and orientation can be calculated. The geometrical aspects of the model were tested with literature data. Apart from the apical region the results appear to be satisfactory. Calculated fibre lengths over the wall agree reasonably with measured data, if rather realistic ventricular shape changes were applied. The mechanical aspects (pressure generation, developed flow) were also tested with experiments on rabbit hearts. They agree with previous results obtained from a cylindrical model.
Using Homophone Game to Improve Students’ Pronunciation at Junior High School 5 of Tidore Archipelago

This study was conducted to examine the effect of homophone game towards the students’ pronunciation improvement. Designed as a classroom action research, this study took place in the state junior high school 5 of Tidore archipelago. The researcher involved 20 students as the participants of the research. Through two cycles, the analysis of the data indicated that homophone game could improve the students’ pronunciation.
Evaluation of outage probability for uniformly distributed users based on signal-to-interference-plus-noise ratio

Improving the performance of wireless networks to maintain good quality of service for all users is always an ultimate goal. To reach this goal, the performance should be evaluated accurately and then analysed. Geometric modelling of wireless networks is drawing significant attention with regard to analytically evaluating the performance. In this study, stochastic modelling of users is used to emulate their distribution in wireless networks, which is analysed when only one direct link is connecting the base station to each user over the cell. Hence, the final findings will be more universal and applicable for different types of mobile cellular networks. Probability density function (PDF) of signal-to-interference ratio, and signal-to-noise ratio are evaluated, and used to find the PDF of signal-to-interference-plus-noise ratio (SINR) in a uniform filed of interference. Then, the outage probability based on SINR is evaluated, since it is one of the important factors in studying the performance of wireless networks. Finally, simulations are performed in order to validate the analytical results.
Microsoft Word-32346313-file00

Positive allosteric modulation of the type-A γ -aminobutyric acid receptor (GABA A R) via the benzodiazepine recognition site is the mechanism whereby diverse chemical classes of therapeutic agents act to reduce anxiety, induce and maintain sleep, reduce seizures, and induce conscious sedation. The binding of such therapeutic agents to this allosteric modulatory site increases the affinity of GABA for the agonist recognition site. A major unanswered question, however, relates to how positive allosteric modulators dock in the 1,4-benzodiazepine (BZD) recognition site. In the present study, the x-ray structure of an acetylcholine binding protein from the snail Lymnea Stagnalis and the results from site-directed affinity-labeling studies were used as the basis for modeling of the BZD binding pocket at the α 1 / γ 2 subunit interface. A tethered BZD was introduced into the binding pocket, and molecular simulations were carried out to yield a set of candidate orientations of the BZD ligand in the binding pocket. Candidate orientations were refined based upon known structure-activity and stereospecificity characteristics of BZDs and the impact of the α 1 H101R mutation. Results favor a model in which the BZD molecule is oriented such that the C5-phenyl substituent extends approximately parallel to the plane of the membrane, rather than parallel to the ion channel. Application of this computational modeling strategy, which integrates site-directed affinity labeling with structure-activity knowledge to create a molecular model of the docking of active ligands in the binding pocket, may provide a basis for the design of more selective GABA A R modulators with enhanced therapeutic potential.
Controlled Release of H2S and NO through Air-Stimulated Anion Exchange

H<sub>2</sub>S and NO are gas molecules with physiological activities; solid materials that release these gases under safe and ubiquitous stimuli offer broad medical applications. Herein, we report solid materials that autonomously release ppm-level H<sub>2</sub>S or NO under air. HS<sup>−</sup> or NO<sub>2</sub><sup>−</sup> incorporated in the interlayer of layered double hydroxide (LDH), a clay mineral, is protonated by CO<sub>2</sub> and H<sub>2</sub>O, yielding H<sub>2</sub>S or HNO<sub>2</sub>. HNO<sub>2</sub> generates NO through disproportionation or reduction. Moreover, another NO-release method employs solid mixtures of NO<sub>2</sub><sup>−</sup>-incorporated LDH and FeSO<sub>4</sub>, wherein wet air triggers NO<sub>2</sub><sup>−</sup> reduction with Fe<sup>2+</sup> through anion exchange between NO<sub>2</sub><sup>− </sup>and<sup> </sup>SO<sub>4</sub><sup>2−</sup>. A potential application of the air-stimulated gas release system is demonstrated by creating a portable and battery-free NO inhaler for emergency treatment of respiratory distress.
Where does new information come from?

The article is an attempt to describe the conditions that lead to the creation of new information (which usually starts the process of publishing), as part of the process of scientific research. models of information behaviour most frequently mentioned in the literature from sources like Wilson, dervin, Godbold, Belkin et al. were taken under consideration. The author’s own model is proposed, based on the assumptions of the Rosenblatt transactional theory and concepts of information load, which is a reference to the concepts of anomalous states of knowledge and information gap.
ANALYSIS OF PROPERTIES OF CONCRETE USING NYLON FIBER AS FIBER REIGNFORCEMENT ADMIXTURE OF PROPERTIES OF CONCRETE USING NYLON FIBER AS FIBER REIGNFORCEMENT ADMIXTURE.”

As building industry evolves, stronger more durable and increasingly specialized products are in demand fiber reinforcement took an important role, fiber reinforcement to meet requirement changed with material composition and patterns such as fiber mesh, micro fibers, macro fibers, etc. In this paper analysis of properties of concrete using nylon fiber as fibre reinforcement admixture is studied and verified the strength of concrete to the normal Portland cement. Using nylon fiber the compressive strength and flexural of concrete has increased to very limited extend. As the friction between concrete and nylon fiber is very less, so it gives very less interlocking between concrete.
A Linear MMSE Receiver for Multi-Antenna SWIPT-enabled Wireless Networks

In this paper, we evaluate the performance of a linear minimum mean square error (MMSE) receiver in the context of simultaneous wireless information and power transfer (SWIPT)-enabled cellular networks. In contract to the existing works, where a single-antenna SWIPT architecture is mainly considered, we focus on the SWIPT performance of the multi-antenna receiver architecture, based on the antenna switching (AS) and power splitting (PS) techniques. Aiming to further boost the network performance, we investigate a scenario where the receivers have the capability to employ a successive interference cancellation (SIC) scheme. By leveraging tools from stochastic geometry, we establish an analytical and tractable framework to evaluate the information decoding (ID) and the energy harvesting (EH) success probabilities of the considered network topologies. Our results reveal that the ID performance achieved by the MMSE receiver outperforms that of the conventional maximum ratio combining, leading to an enhanced EH performance, for a given ID reliability constraint. Moreover, by allocating an equal fraction of resources for ID and EH purpose, the PS scheme outperforms the AS in terms of both ID and EH success probabilities.
Effect of oral administration of chia ( Salvia hispanica L . ) seed extract on wound healing property in diabetic mice

IChia, Salvia hispanica L. , a plant containing lipid-antioxidant, has been shown to be beneficial for prevention of risk fac tors of type 2 diabetes. The objectives of this study were to evaluate effects oral chia seed extract on wound healing prop erties including wound contraction and histopathological examination in a diabetic wound model. C57BL/6J mice were fed with standard and high-fat diet for 27 weeks. The mice were divided into 4 groups (n=6) as follows: a non-diabetic group (normal control group) and 3 diabetic groups (4% chia seed extract group, glipizide group, diabetic group). The percentage of wound contraction, histopathological score and morphology were compared for evaluating wound healing properties. On day 12 post-wounding, there were statistically significant differences (p <0.05) in the percentage of wound healing and histopathological score in the normal control, 4% chia seed extract, glipizide group, as compared to diabetic group (99.45 ± 0.865, 98.99 ± 1.948, 99.06 ± 0.779, 81.41 ± 10.759 and 10.50 ± 0.837, 10.00 ± 0.632, 9.92 ± 1.625, 3.83 ± 1.169, re -spectively). The results of histopathological morphology showed consistent results with histopathological scores, in which collagen, fibroblast, epithelialization and neovascularization were dominant in granulation tissue of better scores. It may be concluded that chia seed extract was beneficial for diabetic wound healing in mice