Miracle-dz/UniFAR-FTUs huggingface dataset:
Classification of scenes based on multiway feature extraction

Recognition of real world scenes can be efficiently solved based on global features termed the Spatial Envelope. Such features indeed comprise multiple modes such as orientations, scales, sparsity profiles. In order to extract features and classify multiway samples, most approaches vectorize data tensors to convert the classification of multiway data into the one of 1-D samples. This common approach disregards the multiway structures of global features, hence it can face the risk of losing correlation information between modes (orientations or scales). To this end, by revisiting the problem of scene classification in view of tensor decompositions, a new method is introduced to extract multiway features. The projection filter is designed for global features based on a set of basis matrices instead of only one basis as in 1-D problem. The proposed approach not only improves the classification accuracy, but also reduces the running time for training stage and feature projection.
"Isothermal" density perturbations in an axion-dominated inflationary universe.

In inflationary models of the Universe which are axion dominated both adiabatic and isothermal density perturbations arise. We point out that the isothermal perturbations can be more important than the adiabatic perturbations and discuss a model for which this is the case. With isothermal perturbations the spectrum of density perturbations when structure formation begins is flatter and we briefly discuss the implications of this fact. That the amplitude of isothermal fluctuations not be too large provides yet another constraint on models of inflation.
The effect of ethoxylated oleyl-cetyl alcohol on metabolism of some fungi and their potential application in mycoremediation

The effect of ethoxylated oleyl-cetyl alcohol at a concentration of 1% on the growth and metabolism of A. tenuis Nees and P. verrucosum Dierckx was examined in this paper. The fungal growth was investigated by monitoring the diameter of colonies on solid media and dry weight biomass in liquid media. A. tenuis had better response to applied pollutant in solid medium, whereas P. verrucosum had better response in liquid medium. During exponential fungal growth in liquid media with and without pollutant (control), the following physico-chemical and biochemical parameters were carried out: pH, quantity of free and total organic acids, proteins, carbohydrates, proteolytic activity. The ethoxylated oleyl-cetyl alcohol had influence on decrease in pH value and increase in free organic acids of both fungi. Furthermore, it has influenced production in way that lower amount of total organic acids, proteins, glucose and fructose were gained in fermentation broth of P. verrucosum compared to A. tenuis. The proteolityc activity of fungi was partially (A. tenuis) or fully inhibited (P. verrucosum) by presence of pollutant in liquid medium. Based on the obtained results, these fungal species act as potential candidates for mycoremediation of alcohol ethoxylated contaminated environments and biotechnology. [Projekat Ministarstva nauke Republike Srbije, br. III 43004]
Professional practice assessment in ambulatory private rheumatology: a pilot evaluation of the medical file content for rheumatoid arthritis.

OBJECTIVE Professional Practice Assessment (PPA) has become an obligation for all physicians in France, however its modalities remain unclear. The objective of this work was to evaluate the feasibility and accuracy of a PPA for private practice rheumatologists performed in the context of a network. METHODS A list of items considered mandatory to collect during an outpatient visit for rheumatoid arthritis, was prepared by the network. Non hospital-based rheumatologists, members of the network then evaluated some of their patient files selected by chronological order over a one-month period of time using this list. These files were then assessed by another private rheumatologist, member of the group, randomly allocated, using the same list of items. RESULTS Eighty percent of the private-practice doctors accepted to participate. The mean time to evaluate 15 patient files was 2 hours. Agreement between auto-evaluation and external evaluation for each file was good (agreement statistic, 0.75-1.0). Items mandatory to collect were collected in a high proportion of cases (84.6%). CONCLUSION PPA can be performed in the context of a network, auto-evaluation is a valid method and when the list of items is decided on by the network, the data are collected satisfactorily.
A model-based design flow for CAN-based systems

This paper introduces a novel approach for systematical development of CAN-based systems with guaranteed functional correctness and optimal performance. This approach relies on formal methods for faithful modeling and analysis of such systems, whilst taking into consideration the effects of critical parameters, such as bit stuffing and buffer utilization. As a proof of concept, the approach has been applied on existing benchmarks simulating realistic automotive networks. The results are similar to ones obtained using domain-specific tools e.g. NETCARBENCH. Moreover, this work creates new perspectives and reveals potential application for the generation of optimal device configurations for the recently developed CAN FD protocol.
Evolutionary conservation and versatility of a new set of primers for amplifying the ribosomal internal transcribed spacer regions in insects and other invertebrates

The evolutionary conservation and versatility of a new set of nuclear primers for the amplification of the ribosomal internal transcribed spacer regions in insects and other invertebrates have been studied. These primers, conserved across Insecta and other invertebrates, are based on a comprehensive taxonomic survey of the current DNA sequence databases. Their versatility was demonstrated by extensive polymerase chain reaction assays in 16 species from two arachnid orders, eight insect orders, three invertebrate and vertebrate chordate orders and by direct sequencing of the amplified products. The availability of these primers to the insect research community should facilitate the use of internal transcribed spacer regions in intraspecific studies as well as phylogenetic analysis of closely related taxa.
Characterization of a handheld gamma camera for intraoperative use for sentinel lymph node biopsy

Gamma counting probes play an important role in radioguided sentinel lymph node biopsy surgical procedures. The miniaturization of gamma camera components and associated electronics has allowed the introduction of small handheld gamma cameras to be used in place of simple gamma counting probes in these procedures. We report here on the design of a compact handheld gamma camera and first results from the characterization of this device. A handheld gamma camera with field of view 13.2×13.2 mm2 was constructed based on the SensL SPMArray4SL 4×4 pixel SiPM detector coupled to a 4×4 element CsI:Tl scintillator array with crystal size 3.3×3.3×5 mm3. The detector is mounted in a 114×32×26 mm3 ABS plastic enclosure together with a low energy high resolution (LEHR) parallel hole collimator and front end electronics. The total package has a weight of only 320 g. Each SiPM pixel is individually read out using a 2 channel ADC and a custom 8:1 analog multiplexor. The camera is controlled through a custom GUI program written in National Instruments LabView. A preliminary characterization of the detector was performed using a 57Co point source (1 mm diameter). The spatial resolution, measured as the full-width at half-maximum (FWHM) of the crystal response profiles measured by stepping the point source across the detector face in 0.25 mm increments, was 3.46, 3.92, 4.56 and 6.24 mm for source-detector distances of 1, 10, 25 and 50 mm, respectively. The FWHM energy resolution at 122 keV was 40.2% and the detection efficiency was 162.9 and 149.7 cps/MBq for source-detector distances of 1 and 50 mm, respectively. The system count rate vs. incident gamma-ray fluence was linear up to 104 cps.
Energy cost and metabolic regulation during intermittent and continuous tetanic contractions in human skeletal muscle.

Muscle ATP turnover, glycogenolytic, and glycolytic rates were estimated to compare the energy cost and glycolytic regulation of 102.4 s of continuous and intermittent stimulation. Quadriceps femoris muscles of male subjects were stimulated at 20 Hz for one continuous contraction (n = 6) or a series of 64 contractions (1.6 s on, 1.6 s off; n = 6). Leg blood flow was occluded and muscle biopsies were obtained at rest and following 51.2 and 102.4 s of contraction time in both conditions. Isometric force production by the activated knee extensors decreased to 55% of initial contraction force with intermittent and 80% of initial contraction force with continuous stimulation following 51.2 s of contraction time. Corresponding ATP turnover rates were 4.49 +/- 0.39 and 3.80 +/- 0.44 mmol.kg dry muscle-1.s-1. When normalized for tension production the respective energy costs of intermittent and continuous contractions were 3.66 +/- 0.47 and 2.64 +/- 0.36 mmol ATP.kg-1.100 N-1. Glycogenolytic rates were identical during the first 51.2 s of stimulation but glycolysis was higher in the intermittent group (1.05 +/- 0.10 vs. 0.86 +/- 0.11 mmol.kg-1.s-1). We suggest that the increased ATP utilization of intermittent contractions is associated with enhanced Ca2+-transport ATPase activity during relaxation and enhanced actomyosin ATPase activity during the early portion of each contraction. Glycolytic rate is dependent on ATP demand and regulated by allosteric modulators of phosphofructokinase and pyruvate kinase which are released or consumed in the reactions associated with contraction.
Detection of Mycoplasma hyopneumoniae by using rRNA-oligodeoxynucleotide hybridization

A system that uses rRNA-oligodeoxynucleotide hybridization was developed for the detection of Mycoplasma hyopneumoniae. Synthetic oligonucleotide MHP1 was hybridized specifically with M. hyopneumoniae. Furthermore, the detection of M. hyopneumoniae in clinical samples, such as bronchoalveolar lavage fluid and lung lesions from experimentally infected pigs, was evaluated by this assay. The evidence obtained from the assay indicated that the system can be used to efficiently diagnose mycoplasmal pneumonia of swine. Additionally, a nonradioisotopic system with chemiluminescence detection was tested. This system was 10-fold less sensitive than a test that used radioisotopes.
ANALYSIS OF GENES FROM CANNABINOID BIOSYNTHETIC PATHWAY

Cannabis, or hemp, (Cannabis sativa L.) has been grown for thousands of years all around the world for its valuable traits in fabric making industry and traditional medicine. Today it is still considered as an important crop and medicinal plant. The most studied cannabinoids, secondary metabolites of genus Cannabis, are ∆-9-tetrahydrocannabinol (THC) and cannabidiol (CBD). Ratio between THC and CBD content is relevant marker in differentiation of “fiber-type” and “drug-type”. Biosynthesis of THC and CBD is catalyzed by enzymes tetrahydrocannabinolic acid synthase and cannabidiolic acid synthase. Sequence heterogeneity of genes encoding these enzymes in six varieties of industrial hemp, namely ‘Finola’, ‘Tiborszálási’, ‘Tisza’, ‘Kompolti’, ‘Kompolti hybrid TC’ and ‘Carmagnola’, was studied. Partial sequences of cannabidiolic acid synthase gene with numerous indels and single nucleotide polymorphisms were detected. Similar situation was observed in full-length tetrahydrocannabinolic acid synthase sequences. According to PCR marker, three tested varieties were indicated as potentially rich in THC content, what will be verified by HPLC in future.
A multidimensional singular stochastic control problem on a finite time horizon

A singular stochastic control problem in n dimensions with timedependent coefficients on a finite time horizon is considered. We show that the value function for this problem is a generalized solution of the corresponding HJB equation with locally bounded second derivatives with respect to the space variables and the first derivative with respect to time. Moreover, we prove that an optimal control exists and is unique.
A Utility-based Multi-copy Forwarding Algorithm in Delay Tolerant Networks

In delay tolerant networks (DTNs) with uncertainty in node mobility, message forwarding usually employs a multi-copy, opportunistic forwarding scheme to improve delivery probability. Minimizing the delivery latency (delay) and minimizing the number of forwardings (message copies) have been two conflicting goals. On the other hand, utility-based routing has been proposed in multi-hop wireless networks, where a utility is defined as a compound metric that provides a trade-off between delay and forwarding cost. In this paper, we propose the first multi-copy utility-based opportunistic forwarding algorithm in DTNs. The proposed multi-copy opportunistic utility-based forwarding (MOUF) algorithm is able to improve the overall utility representing a user preferred trade-off between delay and forwarding cost so as to satisfy different requirements. Theoretical analysis and extensive simulations are conducted to verify the improved performance of the proposed algorithm.
A fast computational method for near field capacitive couplings

The near-field capacitive couplings are analyzed by using a hybrid method incorporating the finite difference method and the method of moment. A dielectric post is used as the model for analysis. Results from the formerly developed technique of synthetic asymptote are used for comparison. The speed of computation of the developed method is extremely fast.
An algorithm for graph optimal monomorphism

An algorithm for finding the optimal monomorphism between two attributed graphs is proposed. The problem is formulated as a tree search problem. To guide the search the branch-and-bound heuristic approach is adopted, using an efficient consistent lower bounded estimate for the evaluation function of the cost associated with the optimal solution path in the search tree. The algorithm is a generalization of an algorithm for graph optimal isomorphism. The algorithm's potential for engineering application is demonstrated by a simple structural pattern recognition problem and a plant allocation and distribution problem. >
Carbon monoxide uptake kinetics of arterial, venous and capillary blood during CO rebreathing

The uptake and distribution of CO throughout the circulatory system during two different methods of CO rebreathing (2 min ‘Schmidt’ and 40 min ‘Burge’ methods) were determined in nine healthy volunteers. Specifically, the impact of (i) differences in circulatory mixing time (tmix), (ii) CO diffusion to myoglobin (Mb) and (iii) CO wash‐out was assessed on calculated haemoglobin mass (Hbmass). Arterial (a), muscle venous (vm) and capillary samples (c) were obtained simultaneously at 0, 1, 2, 3.5, 5, 7.5, 10, 12.5, 15, 20, 30 and 40 min for determination of carboxyhaemoglobin (HbCO). Carbon monoxide wash‐out was measured from expired air following rebreathing. The rate of CO diffusion to Mb was calculated using the change in HbCO after tmix, and the rate of CO wash‐out. In both methods, HbCOa and HbCOc followed a near‐identical time course, peaking within the first 2 min and decreasing thereafter. The HbCOvm increased slowly and was significantly lower at 1, 2 and 3.5 min in both methods (P < 0.01). The HbCOa peaked significantly higher in the Schmidt method (P= 0.03). Circulatory mixing had occurred by 10 min in most but not all subjects. The rate of CO wash‐out was 0.25 ± 0.13 ml min−1 in the Schmidt and 0.25 ± 0.16 ml min−1 in the Burge method. The rate of CO diffusion to Mb was 0.22 ± 0.11 and 0.16 ± 0.13 ml min−1 (P= 0.63) in Schmidt and Burge methods, respectively. Inhalation of a CO bolus during the Schmidt method results in faster HbCOa uptake but does not greatly shorten tmix or influence rates of CO wash‐out and flux to Mb. The calculated Hbmass depends substantially on the plateau level of HbCO; therefore, it is paramount to ensure HbCO is mixed completely prior to blood sampling, as well as accounting for potential within‐subject alterations of CO exhalation and CO flux to Mb.
Evaluation of Delayed Gastric Emptying in Diabetic Patients With Autonomic Neuropathy by a New Magnetic Resonance Imaging Technique and Radio-Opaque Markers

OBJECTIVE Our objective was to validate a new noninvasive magnetic resonance imaging (MRI) technique for diagnosis of delayed gastric emptying by using radio-opaque markers (ROMs) in diabetic patients with and without cardiovascular autonomic (CAN) and peripheral sensomotoric neuropathy (PSN). RESEARCH DESIGN AND METHODS Fifteen diabetic outpatients were recruited, eight with CAN and PSN (group A, age 28–61 years, mean diabetes duration 27 years) and seven without CAN (group B, age 28–60 years, mean diabetes duration 16 years). Gastric emptying and motility were assessed with ROMs and MRI in random order. After an overnight fast either a test meal (451 kcal) containing a capsule with 10 ROMs is eaten and a supine plain abdominal × ray is taken after 6 h or 500 ml intralipid 10% (550 kcal) is swallowed for the MRI study, using a 1.5 Tesla Gyroscan ACS II (Philips, Eindohoven, The Netherlands). Computer-assisted segmentation of images was used to measure gastric emptying (T1/2, min) over 125 min, contraction frequency (F, min−1), mean contraction amplitude (CA, % basal), and velocity (V, cm/s). Blood glucose was kept constant at 5.0–8.0 mmol/l. RESULTS In group A, 6.1 ± 1.36 ROMs (mean ± SE) were retained in the stomach after 6 h and 0 ROM in group B, indicating a significant delay of gastric emptying in patients with CAN. The MRI study revealed a significantly longer gastric emptying (P < 0.005) in group A (T1/2 = 124 ± 10 min) as compared with group B (T1/2 = 85 ± 18 min). There was no difference in F, CA, and V between the two groups: F 2.9 ± 0.07 and 2.7 ± 0.1 (min−1), CA 26.8 ± 1.2 and 29.6 ± 1.6 (% basal), V 0.43 ± 0.02 and 0.40 ± 0.02 (cm/s), respectively. CONCLUSIONS MRI offers the possibility of visualizing and examining exactly the mechanisms responsible for gastric emptying and is characterized by a high specificity but a lower sensitivity as compared with ROMs, which proved to be an ideal screening test for diagnosis of gastroparesis in clinical practice.
FDUQA on TREC 2005 QA Track

In this year’s QA Track, we participant in the main and document ranking task and do not take part in the relation task. We put the most effort in factoid and definition questions, and very little on list questions and document ranking task. For factoid questions, we use three QA systems: system 1, system 2 and system 3. System 1 is very similar to our last year’s system [Wu et al, 2004] except two main modifications. One is adding an answer validation-feedback scheme. The other is an improved answer projection module. System 2 is a classic QA system that does not use Web. System 3 is a pattern-based system that we used in TREC 2002 evaluation. The main contribution for factoid question is two improvements for Web-based QA system and the system combination. For definition question, we attempt to utilize both the existing definitions in the Web knowledge bases and the automatically generated structured patterns. Effective methods are adopted to make full use of these resources, and they promise high quality response to definition questions. For list questions, we use a pattern-based method to find more answers other than those found in the processing of factoid question. For document ranking task, we only collect the outputs from document searching or answer projection module. In the following, Section 2, 3, 4 will describe our algorithms to factoid, list and definition questions separately. Section 5 will present our results in TREC 2005.
Synopsis of Preterm Birth Genetic Association Studies: The Preterm Birth Genetics Knowledge Base (PTBGene)

Aim: Our goal wasto produce a field synopsis of genetic associations with preterm birth and to set up a publicly available online database summarizing the data. Methods: We performed a systematic review and meta-analyses to identify genetic associations with preterm birth. We have set up a publicly available online database of genetic association data on preterm birth called PTBGene (http://ric.einstein.yu.edu/ptbgene/index.html) and report on a structured synopsis thereof as of December 1, 2008. Results: Data on 189 polymorphisms in 84 genes have been included and 36 meta-analyses have been performed. Five gene variants (4 in maternal DNA, one in newborn DNA) have shown nominally significant associations, but all have weak epidemiological credibility. Conclusion: After publishing this field synopsis, the PTBGene database will be regularly updated to keep track of the evolving evidence base of genetic factors in preterm birth with the goal of promoting knowledge sharing and multicenter collaboration among preterm birth research groups.
Robust SRAM Design via BIST-Assisted Timing-Tracking (BATT)

A BIST-Assisted Timing-Tracking (BATT) scheme is proposed in this paper to facilitate robust read operation in an SRAM design without sacrificing any circuit performance at all. This scheme has very low area overhead since it uses commonly existing memory BIST circuit for tracking the worst-case silicon speed of the bitlines. It is also highly scalable and therefore suitable for an SRAM compiler that needs to support a wide range of different configurations. Measurement results of 8 manufactured chips of a 2 K-bit SRAM design using TSMC 0.18-mum CMOS technology demonstrate that it can indeed rescue one originally failing chip, while still warranting correct functionality of all the other seven chips, even under some injected variations in which conventional schemes may fail badly.
Drugs ten years later: epirubicin.

The first clinical report on adriamycin (doxorubicin), the 14-hydroxydaunomycin derivative, dates back to almost a quarter of a century ago [1]. The initial findings [2], indicating a broad spectrum of antitumor activity as well as cardiac effects, were confirmed within a few years in large case series all over the world [3—7]. During the past two decades, doxorubicin represented the single most effective agent in the treatment of breast cancer, malignant lymphomas, bone and soft tissue sarcomas, and an essential component in numerous drug combinations for the management of various neoplastic diseases of adults and children. The search in experimental animal systems for other anthracycline analogs with better therapeutic index than daunorubicin and doxorubicin has been tenaciously pursued since early 1970s by investigators of Farmitalia Carlo Erba and the Milan Cancer Institute, namely F. Arcamone, A. Di Marco, A. M. Casazza and their coworkers [8-10). Epirubicin (4'-epiadriamycin, epidoxorubicin, Pharmorubicin*) was the first compound of the new series which became available during the late 1970s for phase I and II studies [11, 12]. In 1984, an international symposium held in Milan [13] concluded that there was preliminary evidence in favor of similar treatment efficacy between epirubicin and doxorubicin but the new analog was moderately less toxic than the parent compound in terms of immediate and delayed side effects. During the past decade, epirubicin underwent extensive pharmacologic, toxicologic and therapeutic investigations. It is now the proper time to briefly review what has been achieved in terms of pharmacology, optimal dose, schedule, and cost-benefit ratio in the most important human malignancies. Primarily because of space, this review will not attempt to dissect every single study reported in the medical literature. Readers interested in exhaustive details are kindly referred to the recent papers of Mouridsen et al. [14] and Delozier etal. [15|. Preclinical and clinical pharmacology