Miracle-dz/UniFAR-FTUs huggingface dataset:
Documentation of fungal endophytes of black pepper ( Piper nigrum L.) and t h eir seed transmission studies

The present study envisaged to document the endophytic fungal association with black pepper through a series of in vitro and in planta investigations. Black pepper was found to harbour endophytic fungal flora belonging to the genera Alternaria , Acremonium , Aspergillus , Cladosporium , Chaetomium , Curvularia, Colletotrichum , Fusarium , Humicola , Paecilomyces , Rhizoctonia , Phoma and non-sporulating forms. Further, it was found that the endocarp of black pepper seed is free from culturable endophytic fungi. This was evident from the absence of culturable fungi in in vitro grown black pepper seedlings. The growth of fungi from the seedlings grown under green house conditions reveal that the fungal endophytes establish from fungal propagules falling on the (test) plants that may enter the plant tissues as back ground inoculum and grow as endophyte. This was also supported by the study that the type of endophytic fungi that harbour black pepper plants varied with geographical locations from where the samples were collected.
Apparent Inhibition of fl-Fructosidase Secretion by Tunicamycin May Be Explained by Breakdown of the Unglycosylated Protein during Secretion1

Suspension-cultured carrot (Daucus carota) cells synthesize and secrete,j-fructosidase, a glycoprotein with asparagine-linked glycans. Treatment of the cells with tunicamycin completely in- hibits the apparent secretion of ,B-fructosidase as measured by the accumulation of the radioactive protein in the cell wall or the culture medium. In the past, such a result has been interpreted as an inhibition of secretion by tunicamycin, but we suggest another explanation based on the following results. In the presence of tunicamycin, unglycosylated j%-fructosidase is synthe- sized and is associated with an endoplasmic-reticulum-rich microsomal fraction. Pulse-chase experiments show that the ungly- cosylated #-fructosidase does not remain in the cells and appears to be secreted in the same way as glycosylated ,B-fructosidase; however, no radioactive, unglycosylated j0-fructosidase accumulates extracellularly (cell wall or medium). Protoplasts obtained from carrot cells secrete jl-fructosidase protein and activity, and treatment of the protoplasts with tunicamycin results in the syn- thesis of unglycosylated fi-fructosidase. In the presence of tunicamycin, there is no accumulation of jl-fructosidase activity or unglycosylated j-fructosidase polypeptide in the protoplast incubation medium. These results are consistent with the interpre- tation that the glycans of fi-fructosidase are necessary for its stability, and that in these suspension-cultured cells, the ungly- cosylated enzyme is degraded during the last stage(s) of secretion, or immediately after its arrival in the wall.
CONIFER SEEDLING ESTABLISHMENT ON A ROCK DISPOSAL SITE AT THE MOUNT POLLEY MINE TO ASSESS COMPETITIVE EFFECTS OF VARIOUS HERBACEOUS GROUNDCOVERS WHEN USING BIOSOLIDS AS A SOIL AMENDMENT

A field-scale tree trial was established in 2013 and 2014 on rock disposal site slopes at Mount Polley Mine to evaluate herbaceous groundcovers’ ability to promote coniferous tree growth on parcels amended with biosolids. Parcels were amended with 20 cm of overburden and biosolids were applied at a rate of 110 dry tonnes per hectare (control parcels received no biosolids). The parcels were then seeded with either: native grasses and forbs (at 5 kg/ha or 10 kg/ha), native forbs, fireweed, or unseeded. The control parcels were also unseeded. Lodgepole pine, Douglas-fir, and deciduous tree and shrub seedlings were planted across all parcels. After two and three growing seasons, herbaceous vegetative cover was highest on parcels seeded with native grasses and lowest on the forbs, fireweed, and unseeded parcels. Higher cover was associated with greater competition with conifer seedlings, increased vegetation/snow press, increased herbivory and reduced seedling survival. Growth of the conifers however, was higher on the parcels amended with biosolids compared to control parcels. These results suggest that the understory on biosolids amended soils should be seeded at low seeding rates with native forbs in order to have the highest conifer survival while still providing erosion and invasive plant control.
University of Birmingham Public goods and decay in networks

We propose a simple behavioral model to analyze situations where (1) a group of agents repeatedly plays a public goods game within a network structure and (2) each agent only observes the past behavior of her neighbors, but is affected by the decisions of the whole group. The model assumes that agents are imperfect conditional cooperators, that they infer unobserved contributions assuming imperfect conditional cooperation by others, and that they have some degree of bounded rationality. We show that our model approximates quite accurately regularities derived from public goods game experiments
631 The Sec34/Sec35p complex, a Ypt1p effector required for retrograde intra-Golgi trafﬁcking, interacts with Golgi SNAREs and COPI vesicle coat

UK he Sec34/35 complex was identiﬁed as one of the evolutionarily conserved protein complexes that regulates a cis-Golgi step in intracellular vesicular transport. We have identiﬁed three new proteins that associate with Sec35p and Sec34p in yeast cytosol. Mutations in these Sec34/35 complex subunits result in defects in basic Golgi functions, including glycosylation of T proteins, protein sorting, and retention of Golgi resident proteins. Furthermore, the Sec34/35 complex interacts genetically and physically with the Rab protein Ypt1p, intra-Golgi SNARE molecules, as well as with Golgi vesicle coat complex COPI. We propose that the Sec34/35 protein complex acts as a tether that connects cis-Golgi membranes and COPI-coated, retrogradely targeted intra-Golgi
An Analysis of Correlation Between Seat Positions and Achievements of Students

—It has been a big issue for universities to setup an appropriate environment for their students to learn effectively. Traditionally, professors have been supposed to understand their students, their attitudes to learning, knowledge levels and other factors by themselves. Thanks to the recent development of Information and Communications Technology (ICT), it is possible to collect various kinds of educational data, analyze them, and extract useful knowledge for enhancing education. Such approach is called Educational Data Mining (EDM). This paper, as a part of EDM, deals with the seat occupation data of students in a class. It is often pointed out that students who take seats close to the lecturer tend to have good evaluation scores, or achievements. Our major aim of this paper is to analyze objective data and to investigate how students take their seats, to find if seat locations relate to the students’ achievements, and to investigate if distances of seats between students relate to their differences of achievements.
Formulation and Evaluation of Unidirection BuccoAdhesive Tablet of Sumatriptan Succinate for Migraine Disorder

The objective of this research work was to formulate and evaluate PEO WSR 301 bucco-adhesive tablet in combination with Carbopol 934p for controlled release of Sumatriptan Succinate. To bypass high hepatic first pass metabolism, unidirection bucco-adhesive tablet is selected dosage form for the experimental work. Initially preliminary trials were carried out for the selection of excipients and their relative quantity for incorporation in the dosage form. From the results, Polyethylene oxide-PEO WSR 301 (mucoadhesive polymer) and Carbopol 934p (control release) were selected as a suitable excipients for experimentation. Composition of the mucoadhesive tablet was optimized using 3 2 full factorial design where amount of PEO WSR 301 (X1) and amount of Carbopol 934p (X2) were taken as independent variables and mucoadhesive strength, Drug release at 6 hour and % swelling index taken as response variables. The formulations of design batches were characterized for post compression parameters like weight variation, hardness, thickness, friability, Drug content, swelling index, ex-vivo Mucoadhesive strength, and surface pH, drug release at 6 hr. , ex-vivo residence time, and curve fitting analysis. The optimized formulation was obtained using Minitab software based on desirability value. Characterization of optimized batch was carried out by, ex-vivo permeation study. From the results of meting point, DSC and FTIR study the drug and its compatibility with other excipients was confirmed. λmax of Sumatriptan Succinate was found to be 227 nm and linearity was 0.9995. Mucoadhesive strength and swelling index were in range of 0.25-0.43 N and 45-50% respectively. Drug release at 6hr. was in the range of 87-95%. The Bucco-adhesive of Sumatriptan succinate provides good concept to bypass the extensive hepatic first-pass metabolism. Formulated tablet using PEO-WSR 301 and Carbopol 934p showed good mucoadhesion, release profile, swelling index and permeation behavior. The Sumatriptan Succinate unidirection bucco-adhesive tablet is a promising approach for the effective treatment of disease as it provides control drug release in 6 hr. population worldwide, approximately 600 million people about 28 million in the USA alone. In addition to headache, migraine can be associated with a variety of other symptoms, including diarrhea, cold extremities, facial pallor, nausea, vomiting, and sensitivity to external stimuli such as light, sound, or odor. Such migraines typically last for up to 24h, but can range from 4 to 72h and patients often experience migraine attacks one to two times per month. The oral formulation offers convenience and ease of use but produces unreliable blood levels and inconsistent response. Recurrence (rebound) occurs with these formulations. This common problem with recurrence is likely
Pre-proof Steroid hormones in the aquatic environment

This is a PDF file of an article that has undergone enhancements after acceptance, such as the addition of a cover page and metadata, and formatting for readability, but it is not yet the definitive version of record. This version will undergo additional copyediting, typesetting and review before it is published in its final form, but we are providing this version to give early visibility of the article. Please note that, during the production process, errors may be discovered which could affect the content, and all legal disclaimers that apply to the journal pertain.
improvements to the ASTRA particle tracking code

provides open access, scholarly publishing services to the University of California and delivers a dynamic research platform to scholars worldwide. Abstract: The Astra simulation code has been successfully used in the design of linac and rf photoinjector systems utilizing beams with azimuthal symmetry. We present recently implemented changes to Astra that allow tracking of beams in beamlines without the assumption of any symmetry. The changes especially include a 3D mesh space charge algorithm and the possibility to import 3D electromagnetic fieldmaps from eigensolver programs. Abstract The Astra simulation code has been successfully used in the design of linac and rf photoinjector systems utilizing beams with azimuthal symmetry. We present recently implemented changes to Astra that allow tracking of beams in beamlines without the assumption of any symmetry. The changes especially include a 3D mesh space charge algorithm and the possibility to import 3D electromagnetic ﬁeld maps from eigensolver programs.
WPress: Benchmarking Infrastructure-as-a-Service cloud computing systems for on-line transaction processing applications

—Approaching a comprehensive performance benchmark for on-line transaction processing (OLTP) applications in a cloud environment is a challenging task. Fundamental features of clouds, such as the pay-as-you-go pricing model and unknown underlying conﬁguration of the system, are contrary to the basic assumptions of available benchmarks such as TPC-W or RUBiS. In this paper, we introduce a systematic performance benchmark approach for OLTP applications on public clouds that use virtual machines (VMs). We propose WPress benchmark, which is based on the widespread blogging software, WordPress, as a representative OLTP application and implement an open source workload generator. Furthermore, we utilize a CPU micro-benchmark to investigate CPU performance of cloud-based VMs in greater detail. Average response time and total VM cost are the performance metrics measured by WPress . We evaluate small and large instance types of three real-life cloud providers, Amazon EC2, Microsoft Azure and Rackspace cloud. Results imply that Rackspace cloud has better average response times and total VM cost on small instances. However, Microsoft Azure is preferable for large instance type.
Institutional Knowledge at Singapore Management University Institutional Knowledge at Singapore Management University Hierarchical text classification and evaluation Hierarchical text classification and evaluation

Hierarchical Classiﬁcation refers to assigning of one or more suitable categories from a hierarchical category space to a document. While previous work in hierarchical classiﬁcation focused on virtual category trees where documents are assigned only to the leaf categories, we propose a top-down level-based classiﬁcation method that can classify documents to both leaf and internal categories. As the standard performance measures assume independence between categories, they have not considered the documents incorrectly classiﬁed into categories that are similar or not far from the correct ones in the category tree. We therefore propose the Category-Similarity Measures and Distance-Based Measures to consider the degree of misclassiﬁcation in measuring the classiﬁcation performance. An experiment has been carried out to measure the performance of our proposed hierarchical classiﬁcation method. The results showed that our method performs well for Reuters text collection when enough training documents are given and the new measures have indeed considered the contributions of misclassiﬁed documents.
Leveraging Traits for Highly Interactive Computational Tools in Jupyter

We describe our experience designing and implementing a highly interactive, online computational tool in Jupyter Notebooks. The lessons learned and subsequent design choices can be applied to similar tools in various domains. This tool, Superpower [1], is a graphical interface for a set of functions designed to help users to perform power analysis on their study design in psychology. The supported statistical functions are computationally non-trivial in that each power analysis function requires many multidimensional parameters that unavoidably make use of lists or numpy arrays. It is also highly interactive such that user manipulation of any single value or element may require a cascade of updates to others. We chose an MVC design pattern to separate computational logic from the view. We used ipywidgets for view components such as selection boxes and numeric parameter settings, as it is the de facto standard for interactive components in Jupyter. Additionally, we used Interactive Matplotlib (ipympl) to create features such as a click and drag bar chart. ipywidgets is built on a traits library called traitlets [2]. Traits are object attributes that are designed to create and send a notification upon an event or a change in value. Correspondingly, event listeners are functions or methods designed to respond to these notifications. For example, the IntText widget is frequently used to manipulate the number of subjects in the user interface (UI). An observe function can be used to update the corresponding value in the model upon change of this number in the view (UI).
Anchoring-induced texture & shear banding of nematic polymers in shear cells

We numerically explore texture (resolved by the second-moment of the orientational distribution) and shear banding of nematic polymers in shear cells, allowing for one-dimensional morphology in the gap between parallel plates. We solve the coupled Navier-Stokes and Doi-Marrucci-Greco orientation tensor model, considering both confined orientation in the plane of shear and full orientation tensor degrees of freedom, and both primary flow and vorticity (in the full tensor model) components. This formulation makes contact with a large literature on analytical and numerical (cf. the review [41]) as well as experimental (cf. the review [45]) studies of nematic polymer texture and flow feedback. Here we focus on remarkable sensitivity of texture & shear band phenomena to plate anchoring conditions on the orientational distribution. We first explore steady in-plane flow-nematic states at low Peclet (Pe) and Ericksen (Er) numbers, where asymptotic analysis provides exact texture scaling properties [18, 6]. We illustrate that in-plane steady states co-exist with, and are unstable to, out-of-plane steady states, yet the structures and their scaling properties are not dramatically different. Non-Newtonian shear bands arise through orientational stresses. They are explored first for steady states, where we show the strength and gap location of shear bands can be tuned with anchoring conditions. Next, unsteady flow-texture transitions associated with the Ericksen number cascade are explored. We show the critical Er of the steady-to-unsteady transition, and qualitative features of the spacetime attractor, are again strongly dependent on wall anchoring conditions. Other simulations highlight unsteady flow-nematic structures over 3 decades of the Ericksen number, comparisons of shear banding and texture features for in-plane and out-of-plane models, and vorticity generation in out-of-plane attractors.
Benelearn 2017: Proceedings of the Twenty-Sixth Benelux Conference on Machine Learning, Technische Universiteit Eindhoven, 9-10 June 2017

Recently we have seen a remarkable increase of awareness of the value of data. Whereas companies and governments mainly used to gather data about their clients just to support their operations, nowadays they are actively exploring new applications. For instance, a telecom operator may use call data not only to bill its customers, but also to derive social relations between its customers which may help to improve churn models, and governments use mobility data to chart mobility patterns that help to assess the impact of planned infrastructure works. I will give an overview of my research in this fascinating area, including pattern mining, the analysis of influence propagation in social networks, and ethical challenges such as models that discriminate. Appearing in Proceedings of Benelearn 2017. Copyright 2017 by the author(s)/owner(s).
Recent Progress on Face Anti-spooﬁng against 3D Mask Attack

With the advanced 3D reconstruction and printing technologies, creating a super-real 3D facial mask becomes feasible at an affordable cost. This brings a new challenge to face presentation attack detection (PAD) against 3D facial mask attack. As such, there is an urgent need to solve this problem as many face recognition systems have been deployed in real-world applications. Since this is a relatively new research problem, few studies has been conducted and reported. In order to attract more attentions on 3D mask face PAD, this book chapter summarizes the progress in the past few years, as well as publicly available datasets. Finally, some open problems in 3D mask attack are discussed.
The reciprocal relationship of insolvency proceeding results and economic performance ascertained by the regression analysis method

– The work stems from the hypothesis according to which there is a relationship between the economic performance of a specific country and the results achieved in the given country in insolvency proceedings. To compare the efficiency of the economy, the indicator of gross domestic product per head of population is used for comparative purposes. The authors here use as a departure point the assumption that high economic efficiency, i.e. a high gross domestic product per one inhabitant is possible only in a cases where a high-quality legal and regulatory framework exists. In simpler terms, one could speak of the level of enforceability of law. In this logic, then, it necessarily applies that more developed countries should have better results of insolvency proceedings than less developed countries. Data on yields for creditors, costs for and duration of proceedings are used as a gauge of quality of insolvency proceedings. In this selection, the authors proceed from the conviction that the yield for creditors is the only entirely objective gauge of the success of insolvency proceedings, whilst they further assume that the yield is indirectly proportional to the costs and duration of proceedings. In this area, the authors refer to older works. The authors then declare that the fundamental hypothesis on the relationship of economic efficiency and yield for creditors from insolvency proceedings has successfully been proved. Similarly, further assumptions of the author team have also been proved. Part of the work also includes comparison of data from international survey with real results of insolvency proceedings in the Czech Republic, where, in contrast to other developed countries, there are relatively comprehensive sources based on analyses of specific cases.
CCID_A_319676 1507..1517

1DermResearch, Inc., Austin, TX, USA; 2Suzanne Bruce and Associates, PA, Houston, TX, USA; 3Midwest Center for Dermatology & Cosmetic Surgery, Clinton Township, MI, USA; 4Associated Skin Care Specialists, Fridley, MN, USA; 5Allergan Aesthetics, an AbbVie Company, Irvine, CA, USA; 6Allergan Aesthetics, an AbbVie Company, Madison, NJ, USA Purpose: To evaluate oral setipiprant versus placebo for scalp hair growth in men with androgenetic alopecia (AGA). Patients and Methods: Males aged 18 to 49 years with AGA were enrolled in a double-blind, multicenter, 32-week, phase 2a trial; randomized to twice-daily (BID) 1000-mg (2×500 mg for a total daily dose of 2000 mg) setipiprant tablets or placebo for 24 weeks; and assessed at weeks 4, 8, 16, and 24, with a week 32 follow-up. The study initially included a finasteride 1-mg once-daily group, removed by protocol amendment. Changes from baseline to week 24 in target area hair count (TAHC) and blinded Subject Self-Assessment (SSA) of target area photographs were coprimary efficacy endpoints. Hair growth was also evaluated using blinded Investigator Global Assessment (IGA). Safety assessments included adverse events (AEs) and clinical laboratory tests. Analysis of covariance models were used to test statistical significance for TAHC, SSA, and IGA. Data were summarized without statistical analysis for finasteride. Results: Randomized subjects (N=169) included 74 placebo, 83 setipiprant, and 12 finasteride subjects; 117 (69.2%) and 113 (66.9%) subjects completed week 24 and 32 visits, respectively. Treatment groups had similar baseline characteristics. Neither coprimary efficacy endpoint was met. At week 24, TAHC and SSA findings indicated no hair growth improvements with setipiprant versus placebo. Setipiprant also did not improve hair growth versus placebo per the IGA. Treatment-related AEs, all mild or moderate in severity, occurred in 12.3%, 25.9%, and 25.0% of the placebo, setipiprant, and finasteride groups, respectively. Two treatment-emergent serious AEs (TESAEs), cellulitis and multiple sclerosis, were reported in the placebo group, both unrelated to treatment. No TESAEs were reported with setipiprant or finasteride. Conclusion: Setipiprant 1000 mg BID was safe and well tolerated but did not demonstrate efficacy versus placebo for scalp hair growth in men with AGA.