Miracle-dz/UniFAR-FTUs huggingface dataset:
TOOL BRACING FOR PERFORMANCE IMPROVEMENT IN SIMULATED FEMORAL HEAD-NECK OSTEOCHONDROPLASTY

Introduction Bracing, a strategy employed by humans and robotic devices, can be generally described as a parallel mechanical link between the actor, the environment, and/or the workpiece that alters the mechanical impedance between the tool and workpiece in order to improve task performance. In this study we investigated the potential value of bracing in the context of bone milling to treat cam-type femoroacetabular impingement (FAI) lesions. The goal of this study was to evaluate whether a proposed bracing technique could enable a user to perform a cam resection more accurately and quickly than a currently employed arthroscopic technique. Materials/Methods Test samples consisted of white urethane plastic reproductions of a commercially available adult proximal femur, which were laser scanned to obtain ground-truth surface information. A black cam lesion was then cast onto the surface of the femur in the anterosuperior region of the femoral neck, creating a clear visual resection boundary for the simulated osteochondroplasty. Test subjects were 4 adult males (25 +/− 3 years) with no surgical experience. Test conditions included two binary factors: (1) Braced vs. Unbraced – The braced case introduced a spherical bearing tool support mounted in the approximate anterolateral arthroscopic portal position. (2) Speed vs. Accuracy – The subject was instructed to perform the resection as quickly as possible or as accurately as possible with a moderate regard for time. Following the removal of the lesion, femurs were laser scanned to acquire the post-resection surface geometry, with accuracy being reported as RMS deviation between the pre- and post-resection scans over the anterosuperior neck region. Results In both accuracy and speed cases, bracing tended to reduce errors (on the order of 7–14%) and task duration (on the order of 32–52%), although given the small number of subjects in this pilot study, these differences were not statistically significant. Conclusion These results provide some encouragement that our hypothesis that bracing can improve both speed and accuracy of cam lesion resection by untrained subjects may be true. The standard deviations between subjects are high and are likely due to both the difficulty of the task and differences in experience using handheld power tools, so additional subjects would be needed to verify the trends identified here.
Production of vacancy-oxygen defect in electron irradiated silicon in the presence of self-interstitial-trapping impurities

The enhancement by carbon of vacancy-oxygen (VO) defect formation in electron irradiated silicon was investigated using many samples of various carbon contents. The effect of carbon is well described by a simple analytical model of competing trapping of self-interstitials by VO and by carbon (and by emerging carbon-related defects like CiOi and ICiOi). The trapping ratio by Cs and by VO was determined to be about 0.9, and the optical calibration coefficients for CiOi and ICiOi were deduced. In crystals containing a high concentration of Ge, germanium also acts as a self-interstitial trapping impurity and, thus, enhances VO production. The trapping efficiency of Ge is 1000 times less than that of carbon.
Role of interhemispherical connections in restingstate Functional Connectivity

Faculty of Sciences and Technology Masters Degree in Biomedical Engineering by António Angelo Gouveia Rosa Perez de Almeida The purpose of this thesis was to identify the role of interhemispherical connections in resting-state functional connectivity. Studying brain function in resting-state gives insight into patterns in anatomical connectivity and is increasingly important both as a proxy measure for structural connectivity and as a biomarker for brain changes in disease. We used the Kuramoto Model of Time Delays and Coupled Oscillators to evaluate the effect of reducing the strength of interhemispheric connections on the functional network of the brain, both with and without preserving the Anterior Commissure. Our findings indicate a monotonic reduction in interhemispheric functional connectivity as the strength of structural connections diminish, an increase of intrahemispheric connectivity as the strength of structural connections diminish below 40% of their original value and a unmistakable preservation of functional connectivity after total interhemispheric section when the anterior commissure is preserved, albeit with important quantitative changes in the network. These results present one more step in the way towards complete understanding of human brain. UNIVERSITY OF COIMBRA
Broadlink：从“痛点”入手

面对智能家居这个千亿元级的市场，创业团队该从哪里找到切人点？ “这个行业的痛点特别多，为什么这么多年没有普及下来？ 传统的智能家居太重了＇价格这么贵、动辄数十万元的安装费，通常需要和整体装修一起，底层构架很复杂，坏了还要更换一堆设备很麻烦、人工维护代价不菲，它的痛点都在这儿放着，所以我们找了这几个痛点去做。 ”刘宗孺对《IT经理世界》直言。
Place, Space, and Residential Burglary: A Multi-Level, Spatial Analysis and Theoretical Integration.

RICHARDSON, NICHOLAS J. Place, Space, and Residential Burglary: A Multilevel Spatial Analysis and Theoretical Integration. (Under the direction of William R. Smith.) It is accepted as commonplace that crime is not randomly or evenly distributed across spatial locations. A long line of research has investigated the spatial, temporal, and social processes of geographic areas where crime occurs. Ecological theories of crime such as Social Disorganization and Routine Activities have provided unique insights into the causal mechanisms of these processes. Using hierarchal linear models and testing for cross-level interaction effects, the present study investigates how the broader, community-level characteristics (community is defined as a Census block group) moderate the relationship between micro-level processes (micro level is defined as a faceblock) and residential burglary. Findings provide moderate support for an integrated, multi-level ecological theory of crime. Relevant policy implications and directions for future research are discussed. © Copyright 2012 by Nicholas James Richardson All Rights Reserved Place, Space, and Residential Burglary: A Multi-Level Spatial Analysis and Theoretical Integration by Nicholas James Richardson A thesis submitted to the Graduate Faculty of North Carolina State University in partial fulfillment of the requirements for the degree of Master of Science
Post-Exercise Hypotension Attenuates the Effect of Waist on Vascular Reactivity in Adults of Both Sexes

Souza RAC, Nascimento RL, Souza JA, Almeida CMM, Silva AAS, Carvalho FO, Moraes JFVN, Moreira SR. Post-Exercise Hypotension Attenuates the Effect of Waist on Vascular Reactivity in Adults of Both Sexes. JEPonline. 2012;15(1):87-97. Measurement of the waist circumference has been highlighted as a major factor in increased risk of vascular reactivity and therefore the occurrence of hypertension throughout time. On the other hand, studies investigating the acute effects of exercise on blood pressure have shown the phenomenon of post-exercise hypotension (PEH). The purpose of this study was to analyze the relationship between the waist circumference and vascular reactivity, and to verify if PEH (after a combined exercise session) attenuates this relationship. Fifty adults of both sexes (28.8 ± 7.1 yr; 73.3 ± 13.3 kg; 172.9 ± 8.8 cm) volunteered to perform measurements of waist circumference and vascular reactivity of blood pressure. In addition, 20 individuals (10 males and 10 females; 33.4 ± 6.9 yr, 70.2 ± 15.8 kg, 170.4 ± 11.5 cm) performed a combined session of resistance and aerobic exercise with duration of 36 min and a control session without exercise on the same period of different days and in randomized order. The vascular reactivity was analyzed by the Cold Pressor Test, which was applied at rest to all the subjects (n = 50) and 1 hr after the experimental sessions (n = 20). The findings indicate that there is a relationship between waist circumference and vascular reactivity during (r = .49/.53; P<0.01) and after (r = .52/.55; P<0.01) the Cold Pressor Test. Also, a single combined exercise session at moderate intensity enabled PEH and attenuated the influence of waist circumference in increasing vascular reactivity in adults of both sexes.
Long term trends in seasonal mortality

This article compares the mortality for the January-March quarter in England and Wales with that for the complete year and assesses the likely contributions of reduced air pollution and the increasing use of central heating in relation to recent falls in winter mortality in England and Wales. Data are for 1841-1980. (EXCERPT)
Healthcare workers and antineoplastic drugs : evaluating the risks and identifying determinants of exposure

ii PREFACE.iv TABLE OF CONTENTS . viii LIST OF TABLES. xii LIST OF FIGURES . xiii LIST OF ABBREVIATIONS . xiv ACKNOWLEDGEMENTS . xv DEDICATION . xvii
The influence of sympathetic failure on the skin microcirculation of the diabetic neuropathic foot

The study of diabetic polyneuropathy is complicated by a lack of clear definitions and the absence of a simple reliable test procedure. Recently, a new sensory perception testing device has been introduced for detection of thresholds for electrical stimuli (current perception: CPT) at different frequencies (Neurometer"). We compared stan­ dardized clinical examination scores with measurements of vibratory perception thresh­ old (VPT) and CPT (foot) and obtained reproducibility figures. Participants in the study were healthy controls (Η, η = 33), diabetic patient without clinical signs of neuropathy (DN -, η = 23), diabetics with overt diabetic neuropathy (DN +, η = 22), and patients with a diabetes duration of over 20 years (D20, η = 38). As expected, there were highly significant differences (Wilcoxon) in CPT, VPT and neurological scores between Η / DN and DN + (p < 0.001), but not between DN andH. Correlation between CPT and total as well as partial (reflecting small and large fibre functions) neurological examination score were highest at 2000 Hz (r = 0.88); no advantage of lower frequency CPT could be identified. CPT seemed rather insensitive in detecting neuropathy. Correlations between CPT and VPT were only moderate and maximal at 2000 Hz (r = 0.61). Reproducibility of CPT was good at 2000 Hz (coefficient of variation 13.3 20.2 %), but moderate to poor at lower frequencies (ranging to 62%). We concluded that CPT and VPT quantitative sensory testing is only of limited value, mainly because of high variability and poor reproducibility.
Coexistence of Haemoglobinopathies and Iron Deficiency in the Development of Anemias in the Tribal Population Eastern India

Abstract Iron deficiency is the most prevalent nutritional deficiency and the most common cause of anemia worldwide. Several hemoglobin disorders have also been found to modify the morbidity and mortality of a population. It has been established that coexistence of á and â thalassaemia with abnormal HbS and E may modify the level of haemoglobin in blood. Tribal communities in India constitute the largest tribal population in the world. The present study is the first to report on the interaction of Haemoglobinopathies and Iron deficiency in the development anemias in the tribal population Eastern India. Methods: A total of 450 unrelated subjects of some tribal groups of two states of Eastern India were randomly selected for the study. Blood was collected from the subjects after obtaining consents. Prevalence of anemia was screened followed by tests for hemoglobin disorders and iron study of selected cases. Beta thalassaemia mutations were screened in selected cases. Age and sex matched control groups were chosen for the study. HbE was the most common haemoglobinopathy among the studied groups of the Northeast. Prevalence of Beta thalassaemia (1.6%) is almost nil in the tribal groups. HbE in homozygous states, sometimes in heterozygous states induced anameia among the Mishings, Deoris and Ahoms, but not in Sonowals. Iron deficiency anemia was pronounced among the females of Mishings and Sonowals. Incidence of hemoglobin disorders is very low among the Santhal (1.12%) and this group was the victim of iron deficiency anemias.
Intention‐to‐treat analysis: the parachute revisited

The parachute is a device that is in widespread use by pilots, soldiers, performance artists and recreational skydivers, in order to control the vertical velocity of their fall to earth. The mechanism of action of the parachute is to provide increased drag, countering the force of gravity. This lowers the terminal velocity and allows the descent to be finally stopped by a physiologically acceptable vertical deceleration. Although this mechanism is well accepted by experts in the area, there is only level 5 evidence supporting its use. The practice of evidence-based medicine demands, however, that before a treatment can be recommended for widespread use, satisfactory levels of evidence must exist, proving its efficacy. The landmark paper by Smith and Pell pointed out that, as far as parachute use is concerned, there do not appear to be any good quality, doubleblinded randomized controlled trials supporting its use. Intention-to-treat (ITT) analysis is an epidemiological methodology whereby a subject’s outcome is related only to their initial randomization group, rather than how they were eventually treated. The latter is known as ‘as-treated (AT) analysis’. ITT analysis examines the effects of instituting a population-wide therapy decision in real life, while AT analysis examines the treatment effects on an individual basis. Both analyses, therefore, are applicable under different circumstances, depending on what the question is, and this distinction often leads to misinterpretation and misapplication of study results. While popular in trials of pharmaceuticals, the application of ITT analysis to surgical research has often been met with significant resistance, and led to great inconsistency in the interpretation of even well-conducted trials. In this paper, we wish to extend the experimental model of Smith et al., and assess the effectiveness of parachutes through the use of a hypothetical study, performed using virtual subjects. ITT and AT analysis will both be reported, and difficulties in using these analyses will be discussed.
Video-to-3D

In this contribution we intend to present a complete system that takes a video sequence of a static scene as input and outputs a 3D model. The system can deal with images acquired by an uncalibrated hand-held camera, with intrinsic camera parameters possibly varying during the acquisition. In a (cid:2)st stage features are extracted and tracked throughout the sequence. Using robust statistics and multiple view relations the 3D structure of the observed features and the camera motion and calibration are computed. In a second stage stereo matching is used to obtain a detailed estimate of the geometry of the observed scene. The presented approach integrates state-of-the-art algorithms developed in computer vision, computer graphics and photogrammetry.
Avaliação do paciente em hemodiálise por meio da medida canadense de desempenho ocupacional * Evaluation of the patient in hemodialysis by canadian occupational performance measure

O portador de insuficiencia renal cronica (IRC) em hemodialise sofre diversas alteracoes em sua rotina diaria, havendo a necessidade do desenvolvimento de estrategias capazes de auxilia-lo durante este processo. OBJETIVO: o objetivo foi avaliar a mudanca ocorrida na autopercepcao do portador de IRC em hemodialise sobre seu desempenho ocupacional, apos a intervencao da Terapia Ocupacional. METODO: participaram do estudo 21 portadores de IRC em hemodialise, atendidos na Clinica de Doencas Renais, localizada em Curitiba, PR. Os sujeitos foram avaliados por meio da Medida Canadense de Desempenho Ocupacional - COPM e reavaliados apos periodo de intervencao da Terapia Ocupacional, a qual foi baseada no Modelo Canadense de Desempenho Ocupacional. RESULTADOS: os maiores problemas de desempenho ocupacional apresentados pelos sujeitos foram controlar a dieta liquida e solida, participar de atividades sociais e frequentar cursos. O percentual de sujeitos que apresentou variacao de 2 ou mais pontos nos escores de satisfacao e desempenho foi de 52,4% e 47,6%, respectivamente. A COPM foi capaz de mensurar os problemas existentes no desempenho ocupacional do portador de IRC em hemodialise e principalmente, as mudancas ocorridas apos a intervencao da Terapia Ocupacional.
The Value Of Mentoring To Develop Student Teachers Work-Integrated Learning Skills

Mentors are expected to create an environment in which prospective employees can be trained to be productive and be able to excel when employed. The personal one-on-one mentoring is especially beneficial for potential employees, such as student teachers, to close the gap between theory they are exposed to at higher education institutions (HEIs) and teaching practice in schools. Motivated school mentors are expected to provide student teachers with work- integrated learning (WIL) skills of a high standard, particularly since these mentors are expected to be models of professionalism for the student teachers to emulate. The aim of the study was to investigate whether the one-year Postgraduate Certificate in Education (PGCE) qualification at HEIs adequately develops the WIL skills of student teachers. Therefore, the objectives of the study were to ascertain the relationship between the theoretical knowledge provided by the PGCE curriculum and the development of WIL skills of student teachers in the schools and to determine the perceptions of school mentors of the PGCE to develop the WIL skills of student teachers. The target population for this quantitative study was school mentors of PGCE student teachers. Data were obtained by means of a structured questionnaire for the mentors. It was evident in this study that mentors were well-trained to develop the WIL skills of their prot. The findings of this research, therefore, support the hypothesis that school mentors make a significant contribution to the development of the WIL skills of student teachers in the PGCE programme.
THE EFFECTS OF SLOW-STROKE BACK MASSAGE ON HYPERTENSION IN ELDERLY

Background and Aim: Hypertension is the most common risk factor for cardiovascular diseases in elderly with high cost of treatment and care modalities. This study examines the effect of slow-stroke back massages on hypertension in elderly hypertensive clients. Materials and Methods: This study was carried out in Kahrizak charity foundation for elderly, in 2007. A quasi-experimental quantitative design conducted the study in which blood pressure of two groups of patients before and immediately after the intervention was compared. One hundred and two patients were randomly assigned to either massage or control group. The intervention consisted of slow-stroke back massage (SSBM) with five minutes duration for five consecutive days at time interval 3-7 the afternoon. Data were collected by demographic characteristics form, blood pressure recording form, calibrated mercury sphygmomanometer, and stethoscope. Results: The findings showed that there was no statistically significant difference between groups in average systolic and diastolic blood pressure before implementation of SSBM (P>0.05), but were observed statistically significant difference between two groups after intervention (P<0.05). Friedman test and repeated measures analysis of variance indicated there was statistically significant difference in blood pressure measures day by day. Conclusion: The authors suggest SSBM as an effective nursing intervention for reducing systolic and diastolic blood pressure in elderly hypertensive patients; therefore, it can be used as a component of current and complementary treatment of hypertension.
Democratic power structures in virtual communities

Many social networks and cooperative systems provide spaces for public discourse and opinion formation, but the operators alone determine how these spaces are designed, who may enter them and what rules apply to their use. Although their systems and platforms accommodate virtual communities, they largely elude the influence of the public and the people participating there. This paper describes common organizational, operational and technological solutions for the design of democratized virtual communities. In detail a Voting pattern is presented.
Inhibition of KPNB1 Inhibits Proliferation and Promotes Apoptosis of Chronic Myeloid Leukemia Cells Through Regulation of E2F1

Background Karyopherin-β1 (KPNB1) belongs to the karyopherin superfamily, which functions as shuttling proteins from the cytoplasm to nuclear. A high level of KPNB1 has been reported in various cancers which promotes cell proliferation and inhibits apoptosis. However, the role of KPNB1 in chronic myeloid leukemia (CML) remains uncertain. Methods Expression level of KPNB1 in CML patient samples and cell lines was analyzed by Western blotting. The proliferation assays and colony formation assay were used to study the CML cell proliferation when KPNB1 knockdown in vitro. Next, Western blotting was used to evaluate the effects of KPNB1 on E2F1 and other cell cycle regulators. Then, the location of E2F1 was detected by immunofluorescence. Finally, flow cytometry was used to detect the effect of KPNB1 inhibitor importazole (IPZ) on CML cells. Results In this study, we firstly showed that KPNB1 is over-expressed in CML cells. Targeting KPNB1 with small interfering RNA (siRNA) and IPZ reduced proliferation and induced apoptosis of CML cells. The underlying mechanisms were also investigated that E2F1 nuclear transport was blocked after inhibiting KPNB1 with siRNA, suggesting KPNB1 over-expression mediates the excessive nuclear transport of E2F1 in CML cells. Moreover, the expression of the E2F1 targeted molecule such as c-Myc and KPNA2 was markedly reduced. The IPZ arrested CML cells at G2/M phase and induced cell apoptosis. Conclusion In summary, our results clearly showed that KPNB1 is over-expressed in CML cells and mediates the translocation of E2F1 into the nucleus of CML cells, thereby inhibition of KPNB1 reduced proliferation and induced apoptosis of CML cells which provides new insights for targeted CML therapies.
Virulence Factors Of Carbapenem-Resistant Pseudomonas aeruginosa In Hospital-Acquired Infections In Mansoura, Egypt

Purpose The problem of carbapenem-resistant Pseudomonas aeruginosa in health-care settings is growing worse. This study was conducted to investigate the rate of carbapenemase genes, antibiotic resistance, and virulence factors in carbapenem-resistant P. aeruginosa associated with hospital-acquired infections. Patients and methods Isolates of P. aeruginosa were collected from patients with hospital-acquired infections at Mansoura University Hospital in Mansoura. Carbapenem susceptibility was done by broth dilution. The presence of carbapenemase genes and quorum-sensing genes was assessed by PCR. Production of protease, pyocyanin, twitching motility, hemolytic activity and biofilm formation was evaluated. Results Out of 80 P. aeruginosa isolates, 34 (42.5%) were resistant to carbapenem. Among carbapenem-resistant P. aeruginosa isolates, 21 (61.8%) were carbapenemase producers. The most prevalent gene detected was blaVIM. The frequency of protease, pyocyanin, twitching motility, hemolytic activity and biofilm formation was 76.2%, 58.8%, 83.8%, 93.8% and 77.5%, respectively. Biofilm formation was significantly associated with carbapenem-resistant P. aeruginosa. On the other hand, pyocyanin production was significantly lower in carbapenem-resistant isolates. No correlation existed between carbapenem resistance and any other studied virulence factors or quorum-sensing genes. Conclusion Association of carbapenem-resistant P. aeruginosa with other antibiotic resistance or the presence of virulence factors in hospital-acquired infection may represent a warning that enhances the need for a stringent surveillance program.