Miracle-dz/UniFAR-FTUs huggingface dataset:
Getting burned by frictionless financial markets

The evolution of stock markets into highly accessible, low-cost, virtually frictionless venues has been praised by policymakers and institutional investors. But could frictionless markets actually harm individual investors by increasing impulsive trading driven by heuristics and biases? Using laboratory experiments, we examine how investor performance is impacted by various trading frictions: transaction costs, time delays in placing orders, and tasks requiring cognitive effort. High transaction costs and time delays have no effect or harm performance, while cognitive tasks benefit participants that are most prone to underperforming. Frictions can yield benefits when they help inattentive investors consider information they might otherwise neglect.
From Silos to Solidarity: Case Study of a Patient-Centered, Integrative Approach to Opioid Tapering and Chronic Pain Mitigation in a Multidisciplinary AIDS Clinic

Background: People with HIV (PWH) are at a disproportionate risk for experiencing both chronic pain and opioid use disorder (OUD). Prescription opioid tapering is typically addressed within the “silo model” of medical care, whereby attention is focused solely on opioid addiction rather than also addressing chronic pain management, and limited communication occurs between patient and providers. Objective: This descriptive case study examined an integrative, collaborative care model consisting of Provider, Physical Therapist (PT), and Patient aimed at decreasing chronic pain and opioid use within a multidisciplinary HIV/AIDS clinic. Method: A physical-therapy based model of chronic pain mitigation and physician-driven opioid tapering was implemented. The Provider, PT, and Patient worked collaboratively to address physiological pain, pain coping skills and opioid tapering. A patient case example was used to illustrate the implementation of the model for a future, larger study in the same patient population. Results: This model was feasible in this case example in terms of clinic workflow and acceptability to both the Patient and Providers in this clinic. After the intervention, the Patient’s pain was fully eliminated, and he had ceased all opioid use. Conclusion: Results of this case study suggest that utilizing an integrative, patient-centered approach to both chronic pain management and opioid tapering may be feasible within the context of a multidisciplinary HIV/AIDS clinic. Generalizability is limited by case study model; however, this gives insight into the value of a collaborative alternative compared to a “silo” model of opioid tapering and chronic pain management in preparation for a larger study.
Preneoplastic Event in Mouse Mammary Carcinogenesis Induced In Vitro by N-Methyl-N-Nitrosourea

Mouse mammary epithelial cells can be transformed in primary cultures to preneoplastic and neoplastic states when treated with N-methyl-N-nitrosourea (MNU). Mammary carcinomas arising from MNU-induced hyperplastic alveolar nodules (a type of mouse mammary preneoplastic lesion) contained transforming c-Ki-ras genes when examined by the NIH 3T3 focus assay. Hybridization of allele-specific oligonucleotides to c-Ki-ras sequences amplified by the polymerase chain reaction demonstrated the presence of a specific G-35--->A-35 point mutation in codon 12 in each of the NIH 3T3 foci as well as the mammary carcinomas. This mutation resulted in the substitution of the normal glycine with an aspartic acid. Furthermore, this mutation in the c-Ki-ras proto-oncogenes was also detected in 9 of 10 hyperplastic alveolar nodules. These results demonstrate that the specific c-Ki-ras mutation is a preneoplastic event in MNU-induced mouse mammary carcinogenesis.
A Systematic Review of the Use of Circulating Cell-Free DNA Dynamics to Monitor Response to Treatment in Metastatic Breast Cancer Patients

Simple Summary Currently, the most commonly used method to monitor response to treatment in metastatic breast cancer patients is by radiological imaging. However, these imaging techniques are relatively insensitive and give little to no insight into biological tumor characteristics that might be relevant for the choice of treatment. Circulating tumor DNA (ctDNA), released by tumor cells into the blood of cancer patients, can be used to overcome these shortcomings. Besides the fact that specific alterations are known to predict response to treatment and development of resistance, the total amount of ctDNA is believed to reflect the proliferation rate of the tumor, suggesting ctDNA levels can be used as a general tool to evaluate treatment response. Different methods are available to measure ctDNA primarily based on detection of cancer-specific somatic mutations, DNA methylation, and copy number variations. In this review we have critically analyzed recently published studies using blood-derived ctDNA of metastatic breast cancer patients on multiple time points to monitor disease response in respect to analytical validity and clinical utility. Abstract Monitoring treatment response in metastatic breast cancer currently consists mainly of radiological and clinical assessments. These methods have high inter-observer variation, suboptimal sensitivity to determine response to treatment and give little insight into the biological characteristics of the tumor. Assessing circulating tumor DNA (ctDNA) over time could be employed to address these limitations. Several ways to quantify and characterize ctDNA exist, based on somatic mutations, copy number variations, methylation, and global circulating cell-free DNA (cfDNA) fragment sizes and concentrations. These methods are being explored and technically validated, but to date none of these methods are applied clinically. We systematically reviewed the literature on the use of quantitative ctDNA measurements over time to monitor response to systemic therapy in patients with metastatic breast cancer. Cochrane, Embase, PubMed and Google Scholar databases were searched to find studies focusing on the use of cfDNA to longitudinally monitor treatment response in advanced breast cancer patients until October 2020. This resulted in a total of 33 studies which met the inclusion criteria. These studies were heterogeneous in (pre-)processing procedures, applied techniques and design. An association between ctDNA and treatment response was found in most of the included studies, independent of the applied assay. To implement ctDNA-based response monitoring into daily clinical practice for metastatic breast cancer patients, sample (pre-) processing procedures need to be standardized and large prospectively collected sample cohorts with well annotated clinical follow-up are required to establish its clinical validity.
Full-Color See-Through Three-Dimensional Display Method Based on Volume Holography

We propose a full-color see-through three-dimensional (3D) display method based on volume holography. This method is based on real object interference, avoiding the device limitation of spatial light modulator (SLM). The volume holography has a slim and compact structure, which realizes 3D display through one single layer of photopolymer. We analyzed the recording mechanism of volume holographic gratings, diffraction characteristics, and influencing factors of refractive index modulation through Kogelnik’s coupled-wave theory and the monomer diffusion model of photopolymer. We built a multiplexing full-color reflective volume holographic recording optical system and conducted simultaneous exposure experiment. Under the illumination of white light, full-color 3D image can be reconstructed. Experimental results show that the average diffraction efficiency is about 53%, and the grating fringe pitch is less than 0.3 μm. The reconstructed image of volume holography has high diffraction efficiency, high resolution, strong stereo perception, and large observing angle, which provides a technical reference for augmented reality.
Evidence-Based Aerobic Exercise Training in Metabolic-Associated Fatty Liver Disease: Systematic Review with Meta-Analysis

Background: This meta-analysis evaluates the overall effect of the non-pharmacological intervention, aerobic exercise, upon serum liver enzymes levels, glucose metabolism and anthropometric measures amongst patients with metabolic associated fatty liver disease (MAFLD). It also examines whether the effects on these outcomes are moderated by the aerobic training protocol when considered according to the American College of Sports Medicine (ACSM) recommended FITT (frequency, intensity, time, type) principles. Approach and Results: Fifteen randomized control trials were included in the meta-analysis. Compared with usual care, continuous and interval training showed significant efficacy in alanine aminotransferase (ALT) level improvement (MD = −2.4, 95% CI: −4.34 to −0.46 p = 0.015, I2 = 9.1%). Interventions based on all types of aerobic exercise protocols showed significant improvement of intrahepatic triglycerides (MD = −4.0557, 95% CI: −5.3711 to −2.7403, p < 0.0001, I2 = 0%) and BMI (MD = −0.9774, 95% CI: −1.4086 to −0.5462, p < 0.0001, I2 = 0). Meta-regression analysis demonstrated a significant correlation between total intervention time and ALT level (for all aerobic protocols: 6.0056, se = 2.6896, z = 2.2329, p = 0.02; as well as for continuous and interval aerobic protocols: 5.5069, se = 2.7315, z = 2.016, p = 0.04). Conclusions: All types of aerobic exercise protocols are effective at improving intrahepatic triglycerides and lead to a reduction in body mass index. In addition, continuous and interval aerobic exercise may be more effective at improving ALT ≤12 weeks intervention time benefits the management of MAFLD.
Fly Ash and Compost Amendments and Mycorrhizal Inoculation Enhanced the Survival and Growth of Delonix regia in Cu-Ni

Delonix regia, an ornamental tree that can tolerate an elevated level of heavy metals, was evaluated for phytoremediation potential in mine tailings with fly ash, compost, and mycorrhiza. A two-factorial experiment was conducted under screen house conditions using mine tailings from Bamangwato Concessions Limited (BCL) Cu-Ni mine. The treatments are mine tailing (MT) without mycorrhiza (MT – AM), MT with mycorrhiza (MT + AM), MT with 10% fly ash (FA) without mycorrhiza (MT + FA – AM), mine tailings with 10% FA with mycorrhiza (MT + FA + AM), MT with 10% compost (CP) without mycorrhiza (MT + CP – AM), and MT with 10% CP with mycorrhiza (MT + CP + AM). After 40 wk, results showed an interaction effect of amendments and mycorrhiza wherein compost and FA enhanced the survival, AM root colonization, plant height, and dry matter yield of D. regia seedlings. Mycorrhiza further enhanced these growth parameters, especially in pure mine tailings. The As, Cu, Mn, Ni, Pb, and Zn concentration in plant tissues were reduced substantially by FA and compost amendments. Mycorrhiza also reduced the As, Cu, Ni, Pb, and Zn in pure mine tailings but enhanced the concentration of these metals in the presence of FA and compost. These results could be attributed to the decrease of heavy metal availability and increase of nutrients due to FA and compost while mycorrhiza decreased the translocation of heavy metals regardless of the presence of FA and compost. Overall, results indicated that the survival and growth of D. regia in BCL Cu-Ni mine tailings could be enhanced by the combined application of fly ash, compost, and mycorrhiza. Philippine Journal of Science 149 (3): 479-489, September 2020 ISSN 0031 7683 Date Received: 07 Jan 2020
Influence of University Course Experience on Graduate Employability Among Commercial Banks in Kenya

The study sought to establish the influence of university course experience on graduate employability among commercial banks in Kenya. The correlational research design was employed for the study. A sample of 393 graduates was randomly selected from a pool of 33,786 working graduates spread out in 41 commercial banks in Kenya. Data on course experience and employability were collected via modified Course Experience questionnaire, of a reliability level Cronbach α = 0.817, was analyzed using simple linear regression. The study found that course experience of a graduate during training positively influenced his or her employability in the banking sector in Kenya (p< .05). The study recommends that universities should aim at providing the best learning experiences to their trainees because this influences their prospects of employability into the banking sector.
Study on the microcosmic mechanism for coal-gas outburst

Applied the calculation method of quantum chemistry density functional theory,constructed the adsorption model of the coal surface and the CH4.Carried on optimization to the associated system structure which was constructed by the adsorption of the coal and the CH4 molecular at the B3LYP/6-311G calculation level,obtained the geometry structure of adsorption equilibrium state,and calculated the adsorption energy and the vibration frequency,thus it was obtained the microscopic mechanism for coal and gas outburst.In the mine production,the coal and rock mass rupture is caused by the mining working surface surrounding rock stress variation that is caused by the earthquake,mining and so on.The coal and rock mass rupture produces the frequency range broad electromagnetic wave.According to quantum chemistry density functional theory(DFT),it is obtained the adsorption of coal and gas is physisorption by calculation and the adsorption energy is 1.16 kJ/mol.The wide frequency electromagnetic wave is adsorbed in the form of quantum by the associated system which is constructed by the adsorption of coal and CH4,which results in the system from ground state be changed into excited state,making the gas from adsorption state desorption be changed into free state,forming a lot of free state gas,and causing the coal and gas outburst in the weak surface.
Interactive RAFT polymer-decorated gold nanoparticles for biomedical use

The overall aim of this thesis is to investigate the engineering of interactive properties into gold nanoparticles by decorating them with RAFT-based polymers. More specifically, we investigated in detail how the interaction can be engineered between gold nanoparticles mutually, between gold nanoparticles and solid surfaces, livings cells and viruses. In CHAPTER2, we aimed to investigate the effect of salt on the temperature induced reversible aggregation of polymer coated gold nanoparticles, as well as on hydrogen bonding based layer-by-layer assembly with tannic acid. Although the preparation of temperature-responsive gold nanoparticles has been reported via a variety of methods, not much has been reported on how the solvent quality influences the thermosensitive properties of these particles. Therefore, there is still a need to understand the influence of salt on the self-assembly of polymer-gold nanoparticles hybrid structures. The obtained knowhow was then used in CHAPTER3 to develop a salt-driven deposition method, allowing for depositing metal nanoparticles on a wide variety of solid surface under all aqueous conditions. It is known that size, shape and surface chemistry of gold nanoparticles can affect their uptake by living cells. In CHAPTER 4, we aimed to explore how the polymer coating with different hydrophilic-to-hydrophobic ratios affects the cellular uptake of gold nanoparticles. In addition, a novel flow cytometry method was developed for label-free investigation of gold nanoparticles-cell interaction and then used to elucidate in more depth the parameters that play a role in the cellular internalization of gold nanoparticles coated with polymers containing various hydrophilic-to-hydrophobic monomer ratios. The aim of the CHAPTER 5 was to develop a straightforward strategy to fabricate bioactive glycosylated gold nanoparticles, allowing for rapid and sensitive detection of influenza virus. A combination of RAFT polymerization, carbohydrate ligation via reductive amination and thiol-gold self-assembly will be explored to design glycolpolymer decorated gold nanoparticles that exhibit multivalent interaction with hemagglutinin on the surface of the influenza virus. In CHAPTER 6, the results obtained in this thesis were discussed in view of the broader international context and the future developments to be expected in this field of research.
Privacy-Preserving Outsourcing of Medical Image Data using SIFT Descriptor

— Outsourcing huge amount of personal multimedia data in these days become a challenging task for the data owners which is greatly motivated by the advances in cloud computing by using its several resources for cost saving and flexibility. despite these facts, outsourcing of multimedia data may leak the data owner’s private information, such as the personal identity, locations, or even financial profiles.in this paper, we present an effective and practical privacy-preserving computation outsourcing protocol for persuading scale-invariant feature transform (SIFT) over huge encrypted image data. We first explain the previous solutions to this problem which is either efficiency or security issues, and no one can well maintain the important functionality of the original SIFT in terms of distinctiveness and robustness. Next, we present a new scheme that achieves practicality requirements along with the maintenance of its key functionality, by first splitting the original image data and designing two novel efficient protocols for secure calculations like multiplication and comparison, then carefully distributing the feature extracted onto two independent cloud servers. Which results into practically secure solution and outperforms the state-of-the-art, with the original SIFT in terms of various characteristics, including rotation invariance, image scale invariance, robust matching across affine distortion, and an addition of noise and change in 3D viewpoint and illumination. To deal with the privacy of important medical multimedia data we took brain tumor as our case study. The Brain Tumor is affecting many people worldwide. It is not only limited to the old age people but also detected in the early age. The encrypted images are stored in the cloud. From the encrypted images we will check for brain tumor using OpenCV and preserve this information by getting revealed using our proposed method.
DOES FINANCIAL LITERACY EFFECT TO PERFOMANCE AND SUSTAINABILITY OF CULINARY MSMEs IN GREATER JAKARTA?

Abstract This research aims to find out whether financial literacy effects performance and sustainability of culinary MSME. Respondents are 100 managers or owners of culinary MSMEs in Greater Jakarta who are responsible for making decisions regards the business and selected by purposive sampling. Structured questionnaire consisted of type of quiz modified from the Basic Indonesian Financial Literacy Index to determine financial literacy and modification of the EFQM Excellence Model to measure performance based on the perception of how far the respondent reaches the indicators of business results. Questions of business sustainability is modified from the Triple Bottom Line reporting indicator to measure sustainability of business operations in terms of economic, environmental and social aspects. SEM model is used to analyze data. The result showed financial literacy has a significant effect to performance of culinary MSME as well as the performance has a significant effect to sustainability of culinary MSME. However, financial literacy does not have a significant effect to sustainability of culinary MSME. It is strongly recommended to management of culinary MSMEs to increase their management capacity in term of financial literacy especially ability to be engaged with digital and financial technology.Keywords: Business performance, Culinary MSME, Financial literacy, Sustainability
Comparison of ocean heat content from two eddy-resolving hindcast simulations with OFES1 and OFES2

Abstract. The ocean heat content (OHC) estimates from high-resolution hindcast simulations from the Ocean General Circulation Model for the Earth Simulator Version 1 (OFES1) and Version 2 (OFES2), and a global objective analysis of subsurface temperature observations (EN4.2.1) were compared. There was an OHC increase in most of the global ocean over a 57-year period, mainly a result of vertical displacements of neutral density surfaces. However, we found substantial differences in the temporal and meridional distributions of the OHC between the two OFES hindcasts. The spatial distributions of potential-temperature change also differed significantly, especially in the Atlantic Ocean. The spatial distributions of the time-averaged surface heat flux and heat transport from the OFES1 and OFES2 were highly correlated, but differences could be seen. However, these differences, more specifically in the heat transport, were only partially responsible for the OHC differences. The marked OHC differences may arise from the different vertical mixing schemes and may impact the large-scale pressure field, and thus the geostrophic current. The work here should be a useful reference for future OFES users.
Tonality of the Concept “Refugee” in the German Mass-Media Discourse of Different Political Content

Recently, there have been profound social, political and economic changes in Europe, associated with a huge influx of refugees. The relevance of the studied language problem is connected with the changes that took place in Germany which have influenced the state, political parties and the population’s attitude towards refugees, and, in particular, the presentation of the unresolved problems of the hosting and integration of refugees in the publicist discourse. About four years have passed since the crisis began, however, many topics still cause controversy and discussion, which in turn is reflected in the press. The article aims to analyse the tonality of the concept “Refugee” in the German mass-media discourse of different political content. The leading method of the research is the sentiment analysis of the studied concept “Refugee” using sentiment dictionaries and considering articles from liberal (Die Tageszeitung (Taz)), conservative (Deutschland Kurier) and social-democratic newspapers (Stern). As a result of the analysis, it has been found that the social-democratic Stern is the newspaper with the most negative tonality with the arithmetic average of 0.184. The liberal newspaper Die Tageszeitung (Taz) has depicted the refugee crisis with more positive publications with the arithmetic average of 0.374. The conservative newspaper Deutschland Kurier, with the arithmetic average of 0.269, is in the middle. During the analysed period, Stern has 58% negative, 40.3% positive and 1.34% neutral publications. Taz has 53% positive and 47% negative publications, without any neutral articles at all. Deutschland Kurier has more negative materials (57%) than neutral (28%) and positive materials (15%). The materials of the article can be applied in linguistics, stylistics and lexicology of the Russian and German languages; in linguistic regional geography and intercultural communication. The method of dictionary-based sentiment analysis may find further application of the political discourse tonality analysis.