Miracle-dz/UniFAR-FTUs huggingface dataset:
Experiências lógico-matemática: um objeto de aprendizagem de uso integrado de recursos manipulativos digitais

This article presents learning objects developed with Adobe Flash, integrated with a MySql database, which allows a greater interaction between students and teachers. The implementation of this proposal, anchored in the Piagetian theory of knowledge construction, resulted in a set of data that allows us to analyze the possibilities of building an environment that provides logical-mathematical experiences. It presents also, analysis of situations in which the objects were used. Perspectives of continuation and expansion of developing materials are placed as closure of the text. Resumo. Este artigo apresenta objetos de aprendizagem desenvolvidos com Adobe Flash, integrados a um banco de dados MySql, que permite uma interação maior entre alunos e professores. A implementação dessa proposta, ancorada na teoria piagetiana de construção de conhecimentos, resultou num conjunto de dados que nos permite analisar as possibilidades de construção de um ambiente que proporcione experiências lógico-matemáticas. Apresenta, também, análise de situações em que os objetos foram utilizados em um curso de formação continuada para professoras de Educação Infantil. Perspectivas de continuação e expansão da elaboração de materiais são apontadas como fechamento do texto.
Shaping Ability of Superelastic and Controlled Memory Nickel-Titanium File Systems: An In Vitro Study

Improvements in the thermomechanical processing procedures of NiTi wires have led to the development of new NiTi instruments that compose mainly of martensite crystals, making the wire stable at clinical condition. This study aimed at comparing the shaping ability of two rotary nickel-titanium systems manufactured from different NiTi wires. Twenty simulated root canals each with a curvature of 35° in resin blocks were divided into two groups of 10 canals each. Canals in the first group were prepared with superelastic F360 instruments (Gebr. Brasseler, Germany) while canals in the second group were prepared using controlled memory HyFlex®CM™ instruments (Coltène Whaledent, Switzerland). Images were taken before canal preparation and after the use of each instrument. The assessment of the canal shapes was accomplished with a computer image analysis program. Data were statistically analyzed using SPSS program. Within the limitation of this in vitro study, HyFlex®CM™ instruments remained better centered in the apical third of the canals. In most canal segments, no significant differences were observed between either system in the amount of material removed. Both systems were comparable to each other in regards to their ability to enlarge root canal in the same way without procedural errors.
Validation of two Amanita species from eastern North America: A.rhacopus sp. nov. and A.variicolor sp. nov.

Abstract Members of the mushroom genus Amanita usually can easily be identified to the genus in the field, however, species circumscription and identification are often problematic. Several names have been misapplied and cryptic species exist. Here, we formally describe and validate two new species of Amanitasect.Vaginatae from eastern North America that were recognised under the umbrella European names A.ceciliae by past authors: Amanitarhacopussp. nov. and Amanitavariicolorsp. nov.
Continuous-Wave Widely Tunable MgO:PPLN Optical Parametric Oscillator With Compact Linear Cavity

An efficient continuous-wave, widely tunable, intra-cavity optical parametric oscillator (OPO) based on periodically poled MgO:LiNbO<sub>3</sub> (MgO:PPLN) with a compact three-mirror linear cavity was demonstrated. The mode radii of fundamental and OPO cavities with plane and concave mirrors were calculated and theoretically compared. The result shows that the fundamental laser beam could be compressed, and its power density on the MgO:PPLN crystal could be improved by optimizing concave radii of cavity mirrors. Meanwhile, better mode matching between fundamental cavity and OPO cavity could be realized. A widely tunable signal spectrum from 1.43 to <inline-formula> <tex-math notation="LaTeX">$1.79~\mu \text{m}$ </tex-math></inline-formula> and an idler spectrum from 2.62 to <inline-formula> <tex-math notation="LaTeX">$4.16~\mu \text{m}$ </tex-math></inline-formula> were achieved as the OPO system derived by a diode laser end-pumped Nd:YVO<sub>4</sub> crystal laser at 1064 nm. The maximum total output power up to 6.35 W (signal output power of about 4.24 W at <inline-formula> <tex-math notation="LaTeX">$1.60~\mu \text{m}$ </tex-math></inline-formula> and idler output power of about 2.11 W at <inline-formula> <tex-math notation="LaTeX">$3.17~\mu \text{m}$ </tex-math></inline-formula>) and conversion efficiency of 31.6% were obtained at an incident pump power of 20.1 W.
Estimating the Costs of Operating Reserve Provision by Poundage Hydroelectric Power Plants

The transmission system operators are entrusted with the task of ensuring stable and reliable functioning of the power system. In a modern power system, there are three groups of market actors who can be called upon by TSOs to aid in power system operation management: controllable generation, energy storage and controllable load. The owners of these assets can rightfully expect remuneration for their services from the TSO to recoup investment costs and operational expenses. This study is focused on poundage hydroelectric power plants and it strives to estimate the cost of operating reserve provision. Data of the large hydroelectric power plants located on the River Daugava is used for the calculation of costs and validation of the proposed algorithms.
A Super Fast Attitude Determination Algorithm for Consumer-Level Accelerometer and Magnetometer

A super fast attitude solution is obtained for consumer electronics accelerometer-magnetometer combination. The quaternion parameterizing the orientation is analytically derived from a least-square optimization that maintains very simple form. Like previously developed approaches, this algorithm does not require predetermined magnetometer reference vector. It has been proven in the paper that the proposed algorithm is equivalent to two recent representative methods. Computational complexity analysis shows that the proposed algorithm has the least floating-number operations. Comparisons with recent and classical methods indicate the definite superiority of the proposed algorithm on execution time in real embedded applications.
Bridging Neuropsychology and Forensic Psychology: Executive Function Overlaps With the Central Eight Risk and Need Factors

Recent research expanded theoretical frameworks of criminality to include biosocial perspectives. This article advances the biosocial integration into traditional criminological theories by focusing on the potential contribution of executive function (EF) to Andrews and Bonta’s risk-need-responsivity (RNR) model. EF encompasses a collection of abilities critical to adaptive human functioning, many of which seem to underlie criminogenic risk and need factors. Although the assessment of EF can be elusive, research suggests that offenders with antisocial personality disorder (ASPD) experience EF deficits. Theoretical analysis on neuropsychological and forensic concepts suggests that unitary and discrete EF domains underlie the “Central Eight” criminogenic factors that are related to criminal behavior and, by extension, the RNR model of forensic assessment and treatment. Research and conceptual limitations of the current neuropsychological and forensic literature are discussed along with the limits of our theoretical analysis. A call for more theoretical and applied forensic neuropsychological research is presented.
Age-dependent methylation in epigenetic clock CpGs is associated with G-quadruplex, co-transcriptionally formed RNA structures and tentative splice sites

ABSTRACT Horvath’s epigenetic clock consists of 353 CpGs whose methylation levels can accurately predict the age of individuals. Using bioinformatics analysis, we investigated the conformation, energy characteristics and presence of tentative splice sites of the sequences surrounding the epigenetic clock CpGs, in relation to the median methylation changes in different ages, the presence of CpG islands and their position in genes. Common characteristics in the 100 nt sequences surrounding the epigenetic clock CpGs are G-quadruplexes and/or tentative splice site motifs. Median methylation increases significantly in sequences which adopt less stable structures during transcription. Methylation is higher when CpGs overlap with G-quadruplexes than when they precede them. Median methylation in epigenetic clock CpGs is higher in sequences expressed as single products rather than in multiple products and those containing single donors and multiple acceptors. Age-related methylation variation is significant in sequences without G-quadruplexes, particularly those producing low stability nascent RNA and those with splice sites. CpGs in sequences close to transcription start sites and those which are possibly never expressed (hypothetical proteins) undergo similar extent of age-related median methylation decrease and increase. Preservation of methylation is observed in CpG islands without G-quadruplexes, contrary to CpGs far from CpG islands (open sea). Sequences containing G-quadruplexes and RNA pseudoknots, determining the recognition by H3K27 histone methyltransferase, are hypomethylated. The presented structural DNA and co-transcriptional RNA analysis of epigenetic clock sequences, foreshadows the association of age-related methylation changes with the principle biological processes of DNA and histone methylation, splicing and chromatin silencing.
All-Surface Induction Heating With High Efficiency and Space Invariance Enabled by Arraying Squircle Coils in Square Lattice

This paper reports an all-surface induction heating system that enables efficient heating at a constant speed all over the surface independent of the specific location on the surface. In the proposed induction system, squircle coils are placed tangentially in a two-dimensional square lattice as opposed to commonly used hexagonal packing. As a proof-of-concept demonstration, a simple model setup was constructed using a $3 \times 3$ coil array along with a steel plate to be inductively heated. To model surface heating, a set of six locations for the plate was designated considering symmetry points. For all of these cases, power dissipated by the system and the plate’s transient heating were recorded. Independent from the specific plate position, almost equal heating speeds were measured for the similar levels of dissipated energies in the system. Using full three-dimensional electromagnetic solutions, the experimental results were also verified. The findings indicate that the proposed system is proved to enable energy efficient space-invariant heating in all-surface induction hobs.
CG258 Klebsiella pneumoniae isolates without &bgr;-lactam resistance at the onset of the carbapenem-resistant Enterobacteriaceae epidemic in New York City

Objectives To examine the epidemiology of β-lactam resistance in 'clonal group 258' (CG258), a successful KPC clonal group, over 14 years. Methods Isolates were collected from 1999 to 2013 for a study of antibiotic resistance in Enterobacteriaceae in New York City; 515 bloodstream isolates had antibiotic susceptibility data available and 436 were available for a CG258 PCR assay. The 56 resulting CG258 isolates were characterized by MLST, capsular type and ESBL and KPC carriage. KPC-positive isolates were assessed for common KPC plasmid types, KPC subtype and Tn4401 isoform. Results RT-PCR revealed 56 isolates were CG258. Seventeen of the 56 CG258 isolates were phenotypically susceptible to all carbapenems (all KPC negative). Five out of 17 susceptible isolates were of the cps-2 (wzi154) capsule type; none was cps-1 (wzi29). Nineteen out of 28 KPC-2 isolates were cps-1 (wzi29) and 8/10 KPC-3 isolates carried cps-2 (wzi154); however, cps-2 (wzi154) predominated among KPC-2-positive isolates in 2003 and 2004. KPC-2 was first detected in 2003 and KPC-3 was first detected in 2006. KPC-harbouring plasmids pKpQIL (all Tn4401a) and pBK30683 (all Tn4401d) were detected in 16/38 and 6/38 carbapenem-resistant isolates, respectively. Discussion CG258-lineage Klebsiella pneumoniae isolates were completely absent in 1999, but common in 2003. Twenty-one percent of CG258 isolates were susceptible to carbapenems in addition to lacking both common ESBL and blaKPC-mediated resistance. The cps-2 (wzi154) capsule type was common in both these susceptible isolates and in early KPC-2-harbouring isolates, suggesting it was the initial capsule type in CG258. Carbapenem-resistant isolates carried common KPC-harbouring plasmids with the same KPC and Tn4401 isoforms, suggesting frequent clonal spread.
Prevalence and factors associated with antenatal depressive symptoms among women enrolled in Option B+ antenatal HIV care in Malawi: a cross-sectional analysis

Abstract Background: Option B+ has increased the number of pregnant women initiating antiretroviral therapy for HIV, yet retention in HIV care is sub-optimal. Retention may be affected by antenatal depression. However, few data exist on antenatal depression in this population. Aim: Describe the prevalence and factors associated with antenatal depression among Malawian women enrolled in Option B+. Method: At their first antenatal visit, women with HIV provided demographic and psychosocial information, including depression as measured with the locally validated Edinburgh Postnatal Depression Scale (EPDS). Prevalence ratios (PR) for factors associated with probable depression (EPDS ≥6) were estimated with log binomial regression. Results: 9.5% (95% CI: 7.5–11.9%) of women screened positive for current depression, and 46% self-reported a history of depression or anxiety. Women were more likely to screen positive for current depression if they reported a history of depression (adjusted PR: 2.42; 95% CI: 1.48–3.95) or had ever experienced intimate partner violence (1.77; 1.11–2.81). Having an unintended current pregnancy (1.78; 0.99–3.21), being unmarried (1.66; 0.97–2.84), or employed (1.56; 1.00–2.44) had potential associations with probable depression. Conclusions: Probable antenatal depression affected a notable proportion of women living with HIV, comparable to other global regions. Screening for antenatal depression in HIV care should be considered.
Mood Detection and Prediction Based on User Daily Activities

Studies show that mood states influence our daily life quality and activities, and this is not the only way around. Mood also changes because of how we spend our days. In this paper, we use data on users’ daily lives (known as lifelog) to both detect and predict their mood. The states of mood in this paper are based on Thayer’s two-dimensional model of mood. This is the first research to analyze in depth the physical data collected in lifelog and its link to determinants and effects of mood including biometrics, physical activities, sleep quality, diet and user’s environment. Our study shows that such link exists and is significant.
Curcumin induces apoptosis and inhibits angiogenesis in murine malignant mesothelioma

Malignant pleural mesothelioma (MPM) is a rare form of cancer that is associated with asbestos exposure. Unfortunately, current therapies have limited efficacy. Previous studies have indicated that curcumin exerts antiproliferative and antitumor effects, and has low toxicity. The present study aimed to evaluate the anticancer effects of curcumin on the RN5 MPM cell line. The inhibitory effects of curcumin on cell viability were determined using the sulforhodamine B assay. In addition, cell cycle progression was analyzed by propidium iodide (PI) staining and flow cytometry, and curcumin-induced apoptosis was measured by Annexin V/PI double staining. The translocation of apoptosis-inducing factor (AIF) was assessed by western blotting and immunofluorescence, and the expression levels of the phosphoinositide 3-kinase (PI3K)-AKT serine/threonine kinase (Akt)-mammalian target of rapamycin (mTOR) signaling pathway proteins and mitochondria-associated proteins were evaluated by western blotting. In vivo antitumor effects were evaluated in a subcutaneous murine model. Briefly, tumors were harvested from the mice, and immunohistochemistry was conducted to evaluate cell proliferation, apoptosis and angiogenesis. The results indicated that curcumin inhibited RN5 cell viability and induced apoptotic cell death. In addition the findings suggested that curcumin-induced cell apoptosis occurred via the mitochondrial pathway, and caspase-independent and AIF-dependent pathways. Further analysis revealed that curcumin may act as a PI3K-Akt-mTOR signaling pathway inhibitor by downregulating PI3K, p-Akt, p-mTOR and p-p70 ribosomal protein S6 kinase. Furthermore, curcumin inhibited tumor angiogenesis in vivo. In conclusion, curcumin may be potent enough to be developed as a novel therapeutic agent for the treatment of MPM.
Evidence of Racial and Geographic Disparities in the Use of Medicare Observation Stays and Subsequent Patient Outcomes Relative to Short-Stay Hospitalizations

Abstract Purpose: To examine racial and geographic disparities in the use of—and outcomes associated with—Medicare observation stays versus short-stay hospitalizations. Methods: We used 2007–2010 fee-for-service Medicare claims, including 3,555,994 observation and short-stay hospitalizations for individuals over age 65. We estimated linear probability models with hospital fixed effects to identify within-facility disparities in observation stay use, estimated in-hospital mortality, 30- and 90-day postdischarge mortality, return emergency department (ED) visits, and hospital readmissions as a function of placement in observation using linear probability models, propensity-score matching, and interaction terms. Results: We identified racial and geographic disparities in the likelihood of observation stay use within hospitals (blacks 3.9% points more likely than whites, rural 5.4% points less likely than urban). Observation is associated with an increased likelihood of returning to the ED within 30 or 90 days and a decreased likelihood of readmission or mortality, but there are racial and geographic disparities in these outcomes. Conclusion: While observation generally results in improved outcomes, disparities in these outcomes and the use of observation stays within hospitals are concerning and may be driven by clinical and nonclinical factors.
Multi-label Classification for Marine Science and Technology Literature

W313 propose a deep-learning based multi-label text classification model F-CNN for marine science and technology documents. We have set up a data set that covers about 300 thousand marine related fields for multi-label text classification. In order to solve the problem of disequilibrium of class distribution of data sets, we propose two ways of data enhancement which improves the efficiency of the model. Comparing with traditional text classification methods, the new F-CNN model optimizes the structure of traditional Text-CNN models according to the characteristics of the paper data, and has good classification effect and high execution efficiency in multi-label classification of document data.
Maturity of Blockchain Technology in Local Electricity Markets

Currently, blockchain technology is a widely discussed hype in the energy community. It may have the potential to revolutionize the energy system and support the energy transition towards distributed renewable generation. In particular, local electricity markets (LEMs) seem to provide applications for the usage of blockchain technology. Through its innovative design as a distributed and decentralized information system, blockchain supporters see its potential in organizing residential households and prosumers in LEMs. We assess the current maturity of blockchain-based applications for LEMs. To this end, we develop a blockchain maturity model that constitutes a framework for analyzing the current and future maturity of blockchain-based LEMs in a comprehensive structured approach. In a second step, we apply the new blockchain maturity model to an use case of a blockchain-based LEM. Our assessment shows that, in the current status, the project is in an early stage of maturity due to missing regulatory rules and standardization.
A 2.1-Gb/s 12-Channel Transmitter With Phase Emphasis Embedded Serializer for 55-in UHD Intra-Panel Interface

Phase and amplitude emphasis are combined in a 2.1-Gb/s 12-channel transmitter for ultra-high definition (UHD) intra-panel interface. The transmitter performs phase emphasis within the final 2:1 stage of its 20:1 serializer. This reduces data-dependent jitter (DDJ) without increasing IO capacitance by making the timing of bit transitions depend on the previous data. We have also proved the compensation effect of this emphasis by a mathematical analysis. The low-voltage differential signaling (LVDS) driver in the transmitter can accommodate a 300-mV variation in common-mode voltage and swings of 300 mV–1.2 V in the output signal, so as to match the variations between channel characteristics which occur in large displays. A prototype was fabricated in 28-nm CMOS, and occupies 1.35 mm2; it was tested on a 55-in $3840 \times 2160$ thin-film transistor liquid-crystal display (TFT-LCD) intra-panel interface, where it compensated for channel losses exceeding 10 dB, while reducing eye jitter by 38%: phase emphasis is responsible for about half of this reduction.
Which Knowledge Graph Is Best for Me?

In recent years, DBpedia, Freebase, OpenCyc, Wikidata, and YAGO have been published as noteworthy large, cross-domain, and freely available knowledge graphs. Although extensively in use, these knowledge graphs are hard to compare against each other in a given setting. Thus, it is a challenge for researchers and developers to pick the best knowledge graph for their individual needs. In our recent survey, we devised and applied data quality criteria to the above-mentioned knowledge graphs. Furthermore, we proposed a framework for finding the most suitable knowledge graph for a given setting. With this paper we intend to ease the access to our in-depth survey by presenting simplified rules that map individual data quality requirements to specific knowledge graphs. However, this paper does not intend to replace our previously introduced decision-support framework. For an informed decision on which KG is best for you we still refer to our in-depth survey.
Specific Objective Recognition Based on Convolutional Neural Network Transfer Learning

S94 objective recognition not only classifies what category it is, but also detects sub-categories information to confirm the objective is what we want to find. Due to the problem that the number of labeled specific objective images is insufficient, and the subtle different between the specific objective and other objectives in the same category, we proposed an efficient method based on convolutional neural network (CNN) transfer learning. We adopted VGG16 network structure to learn low level visual feature, and the fully-connected layers were redesigned. The method retrained the last fully-connected layer and soft-max classifier, and fine-tuned the model with backpropagation algorithm. The experimental results show that the method makes it possible to use CNN fine-tuning for specific objective recognition with only small scale images, and effectively improves the accuracy of image classification.