Miracle-dz/UniFAR-FTUs huggingface dataset:
A Single-Stage Semi Dual-Active-Bridge AC–DC Converter With Seamless Mode Transition and Wide Soft-Switching Range

In this article, a novel single-phase single-stage ac–dc converter based on semi dual-active-bridge dc–dc converter is proposed for unidirectional power flow applications. Dual-phase-shift (DPS) and single-phase-shift (SPS) modes are adopted individually according to their operation. Only two control variables, which are primary side phase shift and the phase shift between the two bridges, are used. The optimal voltage and current waveforms in different operation modes are analyzed. The detailed transition process between the DPS mode and SPS mode is given, and the mode transition is seamless. The proposed converter can achieve high power factor correction without an inner current tracking loop. In addition, the switches can achieve zero-voltage switching on within a wide operating range and the rectifier diode can obtain zero-current switching off. The power transfer capability, mode transition mechanism, soft-switching range, mode operation range, and parameter design are analyzed. Besides, a 1 kW experimental prototype is built to verify the effectiveness of the proposed control strategy.
Transnational migration entrepreneurship during a crisis: Immediate response to challenges and opportunities emerging through the COVID‐19 pandemic

Abstract The COVID‐19 pandemic has affected transnational migrant entrepreneurs due to deglobalization. It has limited their cross‐border mobility as well as collapsed the international value chain; their multiple embeddedness, which requires them to cope with two or more contexts; and the nature of transnational businesses, which are often more vulnerable than others. While entrepreneurship scholars have rapidly responded to the pandemic, its impact on this specific type of entrepreneur has not been investigated. This exploratory, interview‐based study identified three patterns of the entrepreneurial response of transnational migrant entrepreneurs to the pandemic: (1) balancing between multiple institutions, (2) mobilizing transnational social capital, and (3) adapting transnational value creation. Furthermore, this study identified factors on the individual, network, and macro levels that influence transnational migrants' entrepreneurial response to the pandemic. This study's findings revealed how entrepreneurs leverage cognitive flexibility and resource advantages from their multiple embeddedness to mitigate the adverse situation, find alternative strategic orientations, and explore and exploit emerging opportunities during the pandemic. The results of this study contribute to the emerging scholarly discussions on entrepreneurship under the COVID‐19 pandemic by elaborating on the unique contexts and entrepreneurial agents as well as add value to the literature on transnational migrant entrepreneurs by exploring their crisis response.
Tungsten Catalysts for Visible Light Driven Ofloxacin Photocatalytic Degradation and Hydrogen Production

Some tungsten catalysts of interest that are synthesized are bismuth tungstate (BT) and Tetrabutylammonium decatungstate (TBADT), using two consolidated procedures. BT is used as a photo-catalyst for the simulated solar light degradation of ofloxacin (OFL) antibiotic under relevant real conditions (µg L−1, fresh water) with the limit of 0.05 g L−1 of catalyst. A quantitative drug decomposition occurred following a bi-exponential first-order law, with an efficiency comparable with the most used P25 TiO2 catalyst. The photocatalytic profiles of OFL at µg L−1 and mg L−1 were monitored by high-pressure liquid chromatography (HPLC) coupled with fluorescence (FD) and ultraviolet (UV) detectors. Additionally, the main photoproducts were identified by high-pressure liquid chromatography coupled to electrospray ionization in tandem with mass spectrometry (HPLC-ESI-MS/MS). The catalyst Tetrabutylammonium decatungstate (TBADT) was used as a catalyst to produce hydrogen from glucose and 2-propanol in aqueous solution, providing hydrogen gas evolution up to 10 µmol g−1 h−1.
Alfalfa biotypes with putative enhanced cell wall digestibility and effects on performance of growing beef steers

Abstract Three alfalfa biotypes were chosen based on the presumption that they would be sources of alfalfa herbage that differed in lignin concentration and therefore cell wall digestibility. The hypothesis was that a lesser lignin concentration would result in greater alfalfa neutral detergent fiber (NDF) digestibility and greater beef steer growth performance. The three alfalfa biotypes were HarvXtra (Forage Genetics International), Hi-Gest 360 (Alforex Seeds), and a control alfalfa, LegenDairy XHD (Winfield Solutions LLC). High-moisture wrapped bales were prepared from second-harvest, d 30 crops. Digestibility of NDF was determined using in vitro incubations and a steer digestibility trial. Alfalfa baleage and trace mineral salt were fed to Angus steers (300 kg initial body weight, 4 pens/treatment) in an 83-day growing-phase trial. Alfalfa acid detergent lignin concentrations were 75.6, 71.8, and 63.0 g/kg dry matter (P = 0.34) for LegenDairy, Hi-Gest and HarvXtra, respectively. Based on in vitro total-tract NDF digestibility coefficients, HarvXtra tended (P ≥ 0.09) to have the highest NDF digestibility. Alfalfa biotype affected in vivo apparent total tract digestibility of NDF (P < 0.001) and there was a trend for an effect on acid detergent fiber digestibility (P = 0.051). Hi-Gest and HarvXtra had similar in vivo apparent NDF digestibilities, which were greater than for LegenDairy (P < 0.05). There was no alfalfa biotype effect on daily alfalfa dry matter intake (DMI; P = 0.51) or average daily gain (P = 0.25) by growing steers. The absence of an effect by the novel alfalfa biotypes on DMI by growing steers suggests that the compositional and digestibility differences of the novel alfalfa biotypes compared to LegenDairy were not sufficient to alleviate the limitation of physical fill (if evident) on DMI. If more disparity in cell wall composition and NDF digestibility were to exist between control and reduced-lignin biotypes, then perhaps an advantage in cattle growth performance for a reduced-lignin alfalfa biotype would be detectable.
Does digitalization improve government effectiveness? Evidence from developing and developed countries

ABSTRACT This study aims to analyze the effect of digitalization on government effectiveness in developing and developed countries. It uses a panel methodology with data from 138 countries between 2006 and 2016. The results suggest that a government’s use of information and communication technologies (ICT) improves its effectiveness in both developing and developed countries. However, this effect is stronger in developed than in developing countries. Moreover, we find that the effect of aggregate ICT use by individuals, businesses, and government on overall government effectiveness is greater than that of individual use by each individually. The results are robust after several tests (reverse causality, dynamic effect, sensitivity analysis, heterogeneities, and alternative measurements). These results highlight the fact that governments could fully benefit from digitalization by adopting policies that promote access to and use of ICT at all levels of the economy, that is, the government itself, businesses, and individuals.
Assessment of electronic surveillance and knowledge, attitudes, and practice (KAP) survey toward imported malaria surveillance system acceptance in France

Abstract Objective An electronic surveillance system was released to monitor morbidity and mortality incidence of imported malaria cases, investigate autochthonous cases, and assess chemosensitivity of Plasmodium isolates among travelers to and from endemic areas. The aim of this study is to evaluate the use of an electronic surveillance system for imported malaria in France. Materials and Methods Three main indicators were used to assess the online malaria web-based surveillance system: (1) the quality of the surveillance system; (2) the capacity of the online system to early warning in case of particular events of public health; (3) the knowledge, attitude, and practice of online electronic system by practitioners of malaria network in France. Results Overall, the median time onset a case is reported to the system decrease by 99%, ranging from 227 days (144–309) to 2 days (1–6) in 2006 and 2020, respectively. Conclusion The online malaria surveillance system in France has demonstrated its effectiveness and can therefore be extended to carry out numerous investigations linked to research on malaria.
A Randomized Controlled Trial for Prevention of Postspinal Anesthesia Shivering in Gynecological Surgeries: Mirtazapine vs. Dexamethasone

Background The frequency of shivering regarding regional anesthesia is 55%. Newer effective and tolerable options for postspinal anesthesia shivering (PSAS) prophylaxis are necessary to improve patients' quality of care. This research assessed the impact of preemptive mirtazapine versus preemptive dexamethasone to decrease frequency and severity of PSAS in gynecological procedures. Methods 300 patients booked for gynecological procedures under spinal anesthesia (SA) were randomly apportioned into three groups (100 each) to get one preemptive dose of 30 mg mirtazapine tablet (M group), 8 mg dexamethasone diluted in 100 ml of saline infusion (D group) or placebo (C group) two hours before surgery. Incidence of clinically significant PSAS was the primary outcome. Core temperature, shivering score, hemodynamics changes, adverse events, and patient satisfaction score were documented as secondary outcomes. Results Compared with C group, mirtazapine and dexamethasone decreased incidence of clinically significant shivering (74% vs. 16% and 31%, respectively; P < 0.001). M and D groups had less hypotensive episodes during 5–25 min after intrathecal injection (P < 0.001). 90 min after SA, tympanic temperatures were lower than baseline values in the three groups (P < 0.001). Pruritus, nausea, and vomiting were more often in C group (P < 0.001), whereas sedation was more frequent in M group (P < 0.001). C group had the lowest satisfaction scores (P < 0.001). Conclusion Prophylactic administration of mirtazapine or dexamethasone attenuated shivering with minimal hazards in patients scheduled for gynecological surgeries under spinal anesthesia with priority to mirtazapine. The trial is registered with NCT03675555.
Two-sided assembly line balancing based on modified genetic algorithm

Aiming at the lack of research on two-sided assembly line balancing problem status,the characteristics of two-sided assembly line were analyzed and the special requirements of balancing were studied,the corresponding mathematical model was built.A genetic algorithm was proposed according to the features in two-sided assembly,such as the tasks having operational direction constraints and the operating sequence of tasks in stations correlated with the balancing result.A combinational coding scheme,which was based on sequence and consisted of the task and the assigned direction of the task,was adopted.The feasible genetic operators,which only explored in the feasible solution space,were adopted.Experiments were carried out to demonstrate the performance of the proposed method.
Engineering students� English public speaking: Why is it a nerve-wracking experience?

Mastering English public speaking is required for Engineering students to contribute to the Ministry of Education�s internationalization policy that is manifested in the university�s regulation. �However, English public speaking has become a nerve-wracking experience for L2 learners. This research aims to explore Engineering students� English public speaking anxiety and its causes. The explanatory sequential design is applied. The online-based survey was conducted on 197 first-semester students and semi-structured interviews with 8 most anxious participants. The triangulation data analysis of quantitative and qualitative phases was carried out. The results illustrate that students experience moderate to low public speaking anxiety levels. The reasons for public speaking anxiety are linguistics problems, inhibition, lack of speaking practice, the difficulty for sentence construction from L1 into the target language, fear of peer negative feedback and being assessed, and dealing with unfamiliar topics as well as speaking delivery driven thoughts. Furthermore, teachers' reflexive identity and the appointment system used to determine public speakers become additional pressures. These findings can be used as valuable consideration to design appropriate speaking pedagogy, especially in the context of English for non-English major programs. Recommendation for future research is discussed.
Machine Learning-Based Satellite Routing for SAGIN IoT Networks

Due to limited coverage, radio access provided by ground communication systems is not available everywhere on the Earth. It is necessary to develop a new three-dimensional network architecture in a bid to meet various connection requirements. Space–air–ground integrated networks (SAGINs) offer large coverage, but the communication quality of satellites is often compromised by weather conditions. To solve this problem, we propose an extended extreme learning machine (ELM) algorithm in this paper, which can predict the communication attenuation caused by rainy weather to satellite communication links, so as to avoid large path loss caused by bad weather conditions. Firstly, we use Internet of Things (IoT)-enabled sensors to collect weather-related data. Then, the system feeds the data to the extended ELM model to obtain a category prediction for blockage caused by weather. Finally, this information helps the selection of the data transmission link and thus improves the satellite routing performance.
Characterization of the Immune Cell Infiltration Landscape and a New Prognostic Score in Glioblastoma

Glioblastoma (GBM) is the most aggressive, malignant primary brain tumor, which has abundant tumor-infiltrating immune cells and stroma in the tumor microenvironment (TME). So far, the TME landscape of GBM has not been elucidated. GBM samples were retrieved from TCGA and GEO databases. We used ESTIMATE and CIBERSORT algorithms to calculate risk score associated with TME, and immune cell infiltration (ICI) score of each patient is calculated by PCA. GSEA analysis is explored for each subgroup. Finally, the patient prognosis in different ICI score subgroup is determined. Two ICI clusters are determined in 208 GBM patients, and 207 differentially expressed genes (DGEs) are found between ICI clusters. And then, two gene clusters were determined. Finally, we obtained ICI score for each patient using principal component analysis (PCA). Patients were divided into high and low ICI score subgroups by setting the median as cutoff. Through GSEA, we found ECM-receptor interaction, mTOR signaling pathway, pathways in cancer, TGF-beta signaling pathway, and other immunosuppressive pathway related genes in the low ICI score group. Furthermore, patients with high ICI score group have more better prognosis. Targeting the stroma in GBM may be an effective new therapeutic approach, and the ICI score is an effective potential prognostic classifier of GBM.
Naked-Eye Detection of Morphine by Au@Ag Nanoparticles-Based Colorimetric Chemosensors

In this study, we report a novel and facile colorimetric assay based on silver citrate-coated Au@Ag nanoparticles (Au@AgNPs) as a chemosensor for the naked-eye detection of morphine (MOR). The developed optical sensing approach relied on the aggregation of Au@Ag NPs upon exposure to morphine, which led to an evident color variation from light-yellow to brown. Au@Ag NPs have been prepared by two different protocols, using high- and low-power ultrasonic irradiation. The sonochemical method was essential for the sensing properties of the resulting nanoparticles. This facile sensing method has several advantages including excellent stability, selectivity, prompt detection, and cost-effectiveness.
Association among sleep, depression, and health-related quality of life in patients with non-dialysis chronic kidney disease during the coronavirus disease 2019 pandemic.

BACKGROUND Sleep disturbance is well documented as a crucial element that impairs health. Depression and health-related quality of life (HRQOL), which on behalf of a patient's overall perception of emotional, physical and social well-being, are increasingly emphasized self-reported health outcomes especially during the coronavirus disease 2019 (COVID-19) pandemic. Among dialysis patients, sleep disturbance is associated with depression and poorer HRQOL. The study was designed to depict the prevalence of sleep disturbance, and to explore the association among sleep, depression, and HRQOL in patients with non-dialysis chronic kidney disease (CKD) during the COVID-19 pandemic. METHODS A total of 172 non-dialysis CKD patients enrolled in this cross-sectional study, with sociodemographic and clinical data recorded. Sleep, HRQOL, and depression were evaluated via the Pittsburgh Sleep Quality Index (PSQI), the Kidney Disease Quality of Life 36-Item Short-Form Survey (KDQOL-36), and the 9-item Patient Health Questionnaire (PHQ-9), respectively. RESULTS A total of 100 (58%) met the criteria for poor sleep. Good sleepers had strikingly disparate HRQOL and depression scores compared to poor sleepers. Sleep disorders were significantly associated with decreased HRQOL and increased depression in regression models adjusted or unadjusted for sociodemographic and clinical characteristics. Mediation analysis indicated depression was a significant mediator explaining 51% of the relationship between sleep status with physical component summary (PCS) and played a fully mediating role in the association between sleep and mental component summary (MCS). CONCLUSIONS Our study suggested the high incidence of sleep disorders in patients with non-dialysis CKD during the COVID-19 pandemic, as well as the tight associations among sleep, depression, and HRQOL. Considering the negative influences of sleep and depression on HRQOL, appropriate screening and treatment for these treatable health-related domains are necessary for patients with non-dialysis CKD.
O treinamento resistido reduz a dor em mulheres com fibromialgia

O treinamento resistido (TR) é uma estratégia de intervenção para o tratamento da fibromialgia (FM) que possui baixo custo, fácil acesso, fácil aplicação e efeito positivo na manutenção geral da saúde. Objetivo: Investigar o efeito de quatro semanas de TR na dor de pacientes com FM. Método: Trata-se de um ensaio clínico controlado não randomizado com cinquenta e quatro mulheres com FM (idade: 53,74 ± 8,54 anos). As pacientes foram alocadas no grupo intervenção (n= 33) e no grupo controle (n= 21). A intervenção consistiu em quatro semanas de um programa de TR supervisionado. Para a avaliação da dor foi utilizado um algômetro e a escala visual analógica. Para avaliar as diferenças após a intervenção, foi utilizada a ANOVA de dois fatores. Resultados: Os pacientes do grupo intervenção tiveram redução significativa da percepção da dor e aumento do limiar de dor, mas não houve diferença quando comparados ao grupo controle. Conclusão: A prática do TR por quatro semanas reduz a dor de pacientes com FM, entretanto, não foram encontradas diferenças significativas com o grupo controle. Por esse motivo, os resultados significativos deste estudo devem ser considerados com cautela, reforçando a necessidade de novos estudos.
Intracoronary Application of Super-Saturated Oxygen to Reduce Infarct Size Following Myocardial Infarction

Optimal medical therapy for secondary prevention following acute myocardial infarction reduces non-fatal ischaemic events. Intensive antithrombotic or lipid-lowering approaches have failed to significantly lower mortality. In the past, reduction of infarct size in patients undergoing primary percutaneous revascularisation for acute myocardial infarction had been considered as a surrogate outcome marker. However, infarct size measured by magnetic resonance imaging or SPECT is strongly associated with all-cause mortality and hospitalization for heart failure within the first year after an acute myocardial infarction. Intracoronary administration of super-saturated oxygen (SSO2) immediately after revascularisation is an approach that can be used to reduce infarct size and, therefore, improve cardiovascular outcome in patients with acute myocardial infarction. In this article, we describe the modulation of pathophysiology by SSO2, review the existing trial data and present our first impressions with the technique in real clinical practice.
Effect of Circumferential Grooves and Tip Recess on Stall Characteristics of Transonic Axial Compressor Rotor

In the modern day gas turbine engine compressors have higher loading per stage and hence reduced stability range. Although the optimum performance is located close to stability limit but the flow instabilities arises due to the sudden change in operating conditions may lead to stall. Therefore a sufficient stall margin must be maintained to avoid such situations. The casing and tip treatments offer the stall margin improvement. In the present paper the effects of tip recess, circumferential grooves and combined model on the stall characteristics of a transonic axial flow compressor rotor (NASA rotor 37) has been investigated. The tip recess depth is equivalent to nominal clearance gap of 0.0356 cm. For the second model the six grooves were placed in casing from 20% to 80% of the blade tip chord. The depth of groove is three times of the width (0.4 cm). The separation between the grooves is half of the width. The maximum improvement in stall margin (62.45%) is achieved with circumferential grooves coupled with tip recess with some performance penalties. However the improvement with combined model is marginal as compared to only circumferential grooves model. The stall margin enhancement with tip recess model is 15.50% which is relatively lower than the other two models but with less performance penalties.
Aquaporin-4 Polymorphisms Are Associated With Cognitive Performance in Parkinson’s Disease

Objective Aquaporin-4 (AQP4) facilitates a sleep-enhanced interstitial brain waste clearance system. This study was conducted to determine the clinical implication of AQP4 polymorphisms in Parkinson’s disease (PD). Methods Three-hundred and eighty-two patients with PD and 180 healthy controls with a mean follow-up time of 66.1 months from the Parkinson’s Progression Marker Initiative study were analyzed. We examined whether AQP4 SNPs were associated with an altered rate of motor or cognitive decline using linear mixed model and Cox regression. We then investigated whether AQP4 SNPs were associated with Aβ burden as measured by 18F Florbetapir standard uptake values. Furthermore, we examined if AQP4 SNPs moderated the association between REM sleep behavior disorder (RBD) and CSF biomarkers. Results In patients with PD, AQP4 rs162009 (AA/AG vs. GG) was associated with slower dementia conversion, better performance in letter-number sequencing and symbol digit modalities, lower Aβ deposition in the putamen, anterior cingulum, and frontotemporal areas. In the subgroup of high RBD screening questionnaire score, rs162009 AA/AG had a higher CSF Aβ42 level. rs162009 AA/AG also had better performance in semantic fluency in healthy controls. Besides, rs68006382 (GG/GA vs. AA) was associated with faster progression to mild cognitive impairment, worse performance in letter-number sequencing, semantic fluency, and symbol digit modalities in patients with PD. Interpretation Genetic variations of AQP4 and subsequent alterations of glymphatic efficacy might contribute to an altered rate of cognitive decline in PD. AQP4 rs162009 is likely a novel genetic prognostic marker of glymphatic function and cognitive decline in PD.