Miracle-dz/UniFAR-FTUs huggingface dataset:
Therapeutic efficacy of systemic therapy for colorectal peritoneal carcinomatosis: Surgeon’s perspective

Abstract Treatment choices for colorectal peritoneal carcinomatosis/metastases include systemic therapy and increasingly cytoreductive surgery with intraperitoneal chemotherapy delivery. These options are best considered as complementary and not exclusive alternatives. Two prospective randomized trials support use of peritonectomy procedures and intraperitoneal chemotherapy for colorectal peritoneal carcinomatosis. This overview examines efficacy, limitations and landscape of systemic therapy focusing on colorectal peritoneal carcinomatosis. Observations from literature support notions that (1) systemic therapy provides survival benefit for all prototypical patients with mCRC irrespective of metastatic disease site; (2) the magnitude of this benefit is considerably reduced among patients with peritoneal metastases who consequently experience significantly shorter overall survival; (3) efficacy of systemic therapy improved over time but at a slower pace for those with carcinomatosis; (4) this therapeutic difference has not diminished with introduction of targeted therapy, but perhaps widened; (5) further research of cytoreductive surgery and/or intraperitoneal regional therapies is thus a multidisciplinary responsibility of the entire oncology community; (6) peritonectomy procedures with intraperitoneal regional therapy are not scientifically supported in absence of systemic therapies.
THE USE OF DIALOGUE AS A PSYCHOLOGICAL TOOL FOR TEACHING AND LEARNING PHYSICAL AND LIFE SCIENCES IN AND OUT OF THE CLASSROOM

This study looks at dialogue as a vital tool for teaching and learning in a Physical and Life Science classroom. Dialogue could elicit responses that could raise issues bothering science learners as well as science teachers, while teaching and learning goes on in the classroom or even out of classroom situations. Physical and Life Science is perceived as tough disciplines. This perhaps explains why using dialogue could discover strengths and weakness of both learners and teachers in these disciplines. The data for this qualitative study was collected from a focus group interviews. The response from Both Physical and Life Sciences learners (students), who offer between Mathematics and Mathematics literacy, were interviewed. The feedback from the interviews were transcribed, coded and categorized into themes, as supported by Saldana (2009). The Issues discovered from this study range from, students’ background, creating an authentic environment for teaching and learning through Teacher Pedagogical Content Knowledge (TPCK), learners attitude, language used for communication while teaching and learning. This study got different feedbacks which supported discussions considered by the researcher. These feedbacks are from the Physical and Life Sciences Learners. In this context, Physical Science is made up of Mathematics, Chemistry and Physics. Biology and Health Sciences makes up Life Sciences in this study. The results suggest Learners had different interpretations about their teaching and learning in the classroom. This research was carried out in a township school in South Africa. In this qualitative study, however, it explains how dialogue could be used as a psychological tool (lens) to discover strengths and weakness of both learners and teachers in and out of the classroom learning situation. Article visualizations:
A dynamic hysteresis meter for studying ferrofluids designed for magnetic hyperthermia

An AC magnetometer system is developed to determine the specific absorption rate (SAR) of ferrofluids designed to work in the range of interest for magnetic hyperthermia. The experimental setup contains a set of configurable RL coil sensors (resistance plus inductance) to obtain the inner area of the dynamic hysteresis loops of colloidal dispersions, which are stimulated using a multi-range alternating magnetic field generator. This magnetometer is suitable for covering the frequency band of 100–450 kHz, and special considerations concerning sample size and placement inside the magnetic field region are taken into account. The performance of the system is tested using a ferrofluid of water-dispersed iron oxide nanoparticles. The SAR determined with the developed system is compared with that obtained using the typical calorimetric procedure. The observations are consistent with both kinds of measurement, and also coincide with the results for other previously reported experimental systems.
BIG DATA ANALYTICS FOR SMART CLOUD-FOG BASED APPLICATIONS

The internet connectivity extended by the internet of things to all the tangible things lying around and used by us in our day today life has convert the devices into smart objects and led to huge set of data generation that holds both the valuable and invaluable information. In order to perfectly handle the information’s generated and mine the valuables from them, the analytics are engaged by the cloud. To have a timely access, most probably the fog services are preferred than the cloud as they bring down the service of the cloud to the user edge and reduces the time complexity in accessing of the information. So the paper proposes the big data analytics for the fog assisted health care application to effectively handle the health information’s diagnosed for the aged persons. The proposed model is simulated using the IFogSim toolkit to examine the performance fogassisted smart healthcare application.
Urban morphology aspects on microclimate in a hot and humid climate

Bandung, the capital of West Java province, Indonesia has experienced rapid urbanization, which has affected the urban environment, including its building density, land use, and the quality of urban living. This specific urban morphology has had a significant effect on the urban microclimate. This study was aimed at describing the urban microclimate of three different overcrowded settlements, i.e., Linggawastu (overcrowded settlement), Gerlong Girang (moderately crowded), and Pasir Impun (least crowded). The discussion will detail aspects of the masses and buildings, the distance between buildings, the height of buildings, and the availability of green open spaces to give the perspective of urban morphology toward the microclimate. Fixed weather logger in those three locations were collected over one month, meanwhile the mobile measurements to find the micro-meteorological values of air temperature (Ta), globe temperature (Tg), humidity (RH), and wind speed (v) to define the mean radiant temperature (Tmrt). The measurements provided evidence of the trend of heat trapped in densely populated settlements shown in the diurnal temperature range from Tamax and Tamin (∆Ta) as only 3.2 °C. Meanwhile in Pasirimpun, which is least populated, ∆Ta = 9.5 °C. Linggawastu with building coverage ratio (BCR) > 96% gave the contribution of low Tg=28.3 °C, as there is less insolation penetration to the area. Thus, the PET for two densely populated areas, Linggawastu and Gerlong Girang, tends to be neutral to slightly cool. Nevertheless, this study points out the high humidity in the morning and afternoon, as well as the low air velocity, is a strong affecting factor.
Factores que influyen en la deserción y reprobación de estudiantes de un curso universitario de matemáticas

En este artículo, se reportan datos sobre la identificación de algunos factores que influyen en la deserción y reprobación de estudiantes de un curso de matemáticas en el nivel universitario. La investigación realizada respondió a un diseño mixto, cuantitativo-cualitativo, con predominancia del enfoque cuantitativo. Para la recolección de los datos, se aplicaron cuestionarios, entrevistas y un grupo focal a estudiantes, más un cuestionario a docentes. Algunos aspectos relacionados con el alumnado, como el sexo, área de procedencia, tipo de colegio o institución en donde cursaron la educación secundaria, año de ingreso a la educación universitaria, promedio de las notas de educación secundaria, nota de examen de admisión, categoría de ingreso al curso, horario del grupo matriculado y carrera seleccionada, permiten determinar individuos con riesgo de desertar y reprobar. Entre los motivos que surgen más relevantes para la reprobación, destacan: poca dedicación al estudio de las temáticas del curso, falta de adecuados hábitos de estudio, deficiencia en conocimientos previos, priorización hacia otro curso y falta de interés por el estudio. Por otra parte, en deserción, se mencionan factores como bajo rendimiento académico en el primer examen parcial, priorización hacia otro curso matriculado, deficiencia en conocimientos previos, falta de interés y poca dedicación al estudio del curso. A partir de los resultados obtenidos, surge la necesidad de hacer una revisión de las temáticas incluidas en el programa de la materia y establecer estrategias que insten a una adecuada inserción del estudiantado al primer curso de matemática en el nivel universitario.
SITA standard testing with Humphrey visual field analyzer versus full threshold testing with frequency doubling perimetry: a comparison of patient preference and perception

Purpose: To compare patient preference for Swedish Interactive Threshold Algorithm (SITA) standard 24-2 protocol in Humphrey visual field analyzer (HVF) and full threshold N-30 protocol in frequency doubling perimetry (FDP) by primarily evaluating their perception about the test procedure and test targets along with surveying the factors that influence the patient concentration during perimetry and elements that determine the level of perimetry task difficulty. Methods: This study enrolled a subset of subjects from the Chennai Glaucoma Study. Each subject underwent a comprehensive ophthalmic examination after which they were randomly allocated to perform HVF and FDP with a 30-minute interval between the two procedures. SITA standard 24-2 protocol in HVF and full threshold N-30 protocol in FDP were used. This was followed by the administration of a questionnaire that mainly assessed the components such as (a) the patient preference for test procedure and test targets, (b) the factors influencing the patient concentration during perimetry performance, and (c) the impression about the level of perimetry task difficulty. The patient responses from the survey for each of the subcategories were obtained and analyzed using Chi-square test. Results: A total of 42 subjects with a mean age of 59.7 (SD 9.7) years were included, among which 18 (42.86%) were male and 24 (57.14%) were female. Thirty-two (76.19%) subjects felt both FDP and HVF were easy to perform, eight subjects (19.05%) felt that both perimetry techniques were difficult to perform, and two subjects (4.76%) found FDP procedure was easier than HVF, whereas the distribution was not statistically significant (Chi-square, p = 0.7). Pressing the button as a response to peripheral stimulus perception and inability to maintain steady central fixation for prolonged duration were the most commonly reported factors that influenced the level of difficulty of the perimetry tasks. A dark room ambience set for performing HVF was preferred by 32 (76.20%) subjects. Conclusion: There was no significant difference in the patient preference for test procedure and peripheral test targets. A black central fixation as in FDP and dark room ambience set for HVF were preferred.
MEASURING GOAL ATTAINMENT IN CHRONIC DISEASE SELF-MANAGEMENT WITHIN CLINICAL AND RESEARCH CONTEXTS: DEVELOPMENT AND INITIAL TESTING OF THE GOAL ATTAINMENT OUTCOME MEASURE FOR STROKE (GAM-S)

Background Multiple self-management (SM) interventions have been developed to support stroke survivors in achieving behavior changes to control their stroke risk factors. Goal setting and attainment are fundamental SM skills essential for effective behavior change and secondary stroke prevention. Through the application of valid and reliable measures the most salient elements of effective chronic disease self-management are just beginning to be understood. Purpose The purpose of this study was to identify existing measures of goal attainment applied in the context of SM of chronic conditions in clinical and research contexts and to identify their differential strengths and weaknesses. A secondary objective was to identify current evidence for the impact of goal attainment in effective SM of chronic diseases related to stroke risk. Methods To identify measures of goal attainment for SM of stroke risk factors, in both clinical and research contexts, we applied the Preferred Reporting Items for Systematic Reviews and MetaAnalyses guidelines to complete a systematic review of systematic reviews. We sought to describe differential strengths and weaknesses, and effectiveness of goal attainment measures for patient SM of stroke risk factors. Source databases used were Medline (Ovid), PubMed (National Library of Medicine), Embase (Ovid), and PsycINFO (Ovid). A priori eligibility criteria required
Biotopical variability of Myodes rutilus mandibula shape in the taiga-woodland zone of the south of Western Siberia

The method of geometric morphometry was used to study the variability of the shape of the red vole’s (Myodes rutilus Pallas, 1779) mandibula in the taiga-woodland zone in the south of Western Siberia. A discrepancy in the morphospace of the mandibula shape of animals from the territory of three local biotopes was revealed. The red voles of the extrazonal floodplain biotope differ in both configuration and larger mandibula size in relation to the animals of the taiga and subtaiga subzones.
Gender gaps in child nutrition in Malawi: Does cultural lineage matter?

The paper investigates whether cultural lineage mediates gender gaps in child nutrition. It captures nutrition using height-for-age and stunting. The analysis uses the 2014 Malawi Millennium Development Goals Endline Survey data. We find evidence of male child nutrition deprivation in matrilineal cultural lineage. The gender of the household head does not relate to the mediating role of lineage on gendered nutrition gaps. As such, the analysis of gendered nutrition should account for the potential impact of culture to produce policy relevant estimates. Furthermore, deficiencies in male nutrition remains a strong health problem, particularly in cultures that benefit most from returns on female children. In these cultures, lineage dominates personal parental preferences. Therefore, there is a need to revisit received wisdom that providing more resources to female heads eliminates gender gaps by provision of culture-tailored nutritional interventions.
Pet Imaging Of Early Therapeutic Response In Solid Tumors

PET IMAGING OF EARLY THERAPEUTIC RESPONSE IN SOLID TUMORS by STEPHANIE J. BLOCKER December 2017 Advisor: Dr. Anthony F. Shields Major: Cancer Biology Degree: Doctor of Philosophy An important pillar of precision medicine for oncology is the ability to identify patients who respond to treatment early into their therapy. Positron emission tomography (PET) allows physicians and researchers to measure changes in tumor behavior prior to noticeable differences in morphology. Objective: Determine the utility of multiple tracers for PET in assessing early changes in tumor activity that result from treatment. Methods: Two tracers for PET were studied. Cu-labeled liposomes were used to assess changes in liposome delivery two solid colon tumors early into treatment with bevacizumab (Bev). F-FMAU thymidine analog (1-(2'-deoxy-2'fluoro-beta-D-arabinofuranosyl)thymine), was utilized to detect early response to cisplatin treatment in non-small cell lung tumor models. Scans were analyzed before and after short-term therapy to determine changes in tracer retention which suggest therapeutic response. Results: In each study PET was able to detect changes in tumor behavior which occurred early into treatment. After two injections of Bev over one week,
Referenceless single‐loop CDR with a half‐rate linear PD and frequency acquisition technique

A referenceless single-loop clock and data recovery (CDR) circuit with a half-rate linear phase detector (PD) and an inherent frequency acquisition technique are introduced. Cycle-slip in the half-rate linear PD and its relationship with the frequency acquisition are described in detail. The single-loop CDR consists of a conventional phase-tracking loop and a frequency-tracking unit, referred to as the cycle-slip detector. The proposed CDR is fabricated in a 28 nm CMOS process and achieves a wide capture range of 2.6 Gb/s for a PRBS31 pattern. The RMS and peak-to-peak jitter of the recovered clock are 2.40 psrms and 21.4 ps pp , respectively, at 8 Gb/s. The high frequency jitter tolerance is measured as 0.3 UI pp . The CDR occupies 0.105 mm 2 and consumes 26 mW at 8 Gb/s from a 1.0 V supply.
Pest categorisation of the Gonipterus scutellatus species complex

Abstract The Panel on Plant health performed a pest categorisation of the Australian Eucalyptus snout‐beetle Gonipterus scutellatus (Coleoptera: Curculionidae), for the EU. G. scutellatus should be referred as the G. scutellatus species complex because it includes several cryptic species. A complete nomenclature of the species present in the EU is still pending. It is a quarantine pest listed in Annex IIB of Council Directive 2000/29/EC. Protected zones are in place in Greece and Portugal (Azores). In the EU, it has been found in Italy, France, Spain and Portugal. It only consumes Eucalyptus species leaves. The main pathways of spread are the trade of Eucalyptus timber, hitchhiking in various commodities, trade of apple fruit as well as of plants for planting or plant parts. Spread by flight is also possible. The climate of the EU protected zones is similar to that of the Member States (MS) where the G. scutellatus complex is established, and the pest's main host plants are present. The damaged trees suffer die‐back and the development of epicormics shoots. Severe attacks may provoke massive amounts of tree death. Biological control by using the egg parasitoid wasp Anaphes nitens is the most effective control measure. Some species within the G. scutellatus complex are not yet present in the EU (including G. scutellatus sensu stricto) and might therefore be considered as potential union quarantine pests for the EU territory. At least two species within the G. scutellatus complex (most likely G. platensis and Gonipterus species no. 2) meet the criteria assessed by EFSA for consideration as potential protected zone quarantine pests for the territory of the protected zones: Greece and Portugal (Azores). The criteria for considering the G. scutellatus complex as a potential regulated non‐quarantine pest for the EU are not met since plants for planting are not the main pathway.
Nonmedical Prescription Drug Use Among Adults in Their Late Twenties: The Importance of Social Bonding Trajectories

Although weak social bonds are found to be associated with addictive behaviors in cross-sectional studies, few studies have explored the longitudinal impacts of social bonds on nonmedical prescription drug use (NPDU). This study adopted a developmental perspective on social bonds and tested how their different trajectories are associated with NPDU among adults. With panel surveys from the National Longitudinal Study of Adolescent to Adult Health from 1994 to 2008, this study employed group-based latent trajectory modeling to obtain the different trajectories of social bonds including religious, civic, familial, educational, and marital, and then used them as predictors of NPDU while controlling for potential confounders and the baseline NPDU. The findings show that constant and high-level social bonds significantly reduce the risk of NPDU, except for educational bond. However, for religious, civic, and educational bonds, the “low initial” trajectories are not significantly different from the “high-decrease” trajectories, implying that strong early-life social bonds do not prevent NPDU if such bonds register a recent decline. Weak social bonds constitute significant risk of NPDU for adults in their late twenties, and recent social bonds override the contribution of early-life bonds in most cases. Policy makers may consider strategies to sustain the active and meaningful participation in conventional institutions, and not solely rely on programs that facilitate early-life social integration.
Editor’s Remarks: Diversity, History, Frameworks, and Effects

Radio research has been marked in the last few decades by its expansion to cover different communities, experiences, dig deeper into the past, and use increasingly innovation research methods or techniques. The diverse, original, peer-reviewed research in this issue demonstrates the expansion of the field and the fact that radio touches on so many aspects of society and the media. This issue features articles that represent communities within communities and many around the world. In “New Arenas or More of the Same? Public and Commercial Radio Stations on Facebook” Nili Steinfeld and Tal Laor explore the tendency for Israeli public radio stations to use social media for informational purposes while Israeli commercial stations more frequently use their social media for promotion (Steinfeld & Laor, 2019). Based on the Facebook pages of Israeli radio stations, this work makes recommendations for radio stations’ use of social media. Thokozani Mhlambi argues that “Zulu took its shape in accordance with the demands of authorities, what they felt that people ought to know about, and what Africans listeners themselves wanted to hear. Between what Europeans designated Africans to be, and what Africans knew they were” (Mhlambi, 2019, p. 226) in “African Pioneer: K. E. Masinga and the Zulu ‘Radio Voice’ in the 1940s. ” This thoughtful discussion focuses on the role of voice on Zulu radio. Antenna Dilemmas: The Rise of an Indigenous-Language Low-Power Radio Station in Southern California by Carlos Jimenez conducts an ethnographic study of Radio Indigena, a Low-Power Radio Station, as they applied for an FCC license, setting up an antenna, and launching the station over the internet (Jimenez, 2019). The work is significant because there is a need for more research on low-income, indigenous radio communities. Radio history continues to be a regular feature of this journal’s offerings. Michelle A. Tabbanor’s “Hold Your Liquor: NBC and Alcohol Advertising after Prohibition” navigates NBC’s development of a position that ultimately rejected alcohol advertisements through a study of primary documents (Tabbanor, 2019). Tabbanor’s study examines discourse in the context of the threat of radio censorship. “‘Government Control of Radio Communication:’ The 1918 Debate” by John Mark Dempsey and