Miracle-dz/UniFAR-FTUs huggingface dataset:
Constraint-Based Graphical Layout of Multimodal Presentations

When developing advanced multimodal interfaces, combining the characteristics of different modalities such as natural language, graphics, animation, virtual realities, etc., the question of automatically designing the graphical layout of such presentations in an appropriate format becomes increasingly important. So, to communicate information to the user in an expressive and effective way, a knowledge-based layout component has to be integrated into the architecture of an intelligent presentation system. In order to achieve a coherent output, it must be able to reflect certain semantic and pragmatic relations specified by a presentation planner to arrange the visual appearance of a mixture of textual and graphic fragments delivered by mode-specific generators. In this paper we will illustrate by the example of LayLab, the layout manager of the multimodal presentation system WIP, how the complex positioning problem for multimodal information can be treated as a constraint satisfaction problem. The design of an aesthetically pleasing layout is characterized as a combination of a general search problem in a finite discrete search space and an optimization problem. Therefore, we have integrated two dedicated constraint solvers, an incremental hierarchy solver and a finite domain solver, in a layered constraint solver model CLAY, which is triggered from a common metalevel by rules and defaults. The underlying constraint language is able to encode graphical design knowledge expressed by semantic/pragmatic, geometrical/topological, and temporal relations. Furthermore, this mechanism allows one to prioritize the constraints as well as to handle constraint solving over finite domains. As graphical constraints frequently have only local effects, they are incrementally generated by the system on the fly. Ultimately, we will illustrate the functionality of LayLab by some snapshots of an example run.
Molecular Lipophilicity Calculations of Chemically Heterogeneous Chemicals and Drugs on the Basis of Structural Similarity and Physicochemical Parameters

Abstract QSARs based on molecular polarizability (α) and H-bond acceptor factors (∑Ca) as independent variables provided good predictability of octanol/water partition coefficients (P) for chemicals and drugs. However, for some molecules containing few functional groups, the calculated values deviated significantly from those observed. This approach gave good results when applied to a set of 138 chemicals and drugs previously studied by Mannhold and Dross who compared other methods to calculate log P values. At the same time, three variations on a molecular similarity approach were pursued. In this study, a large training set with experimentally determined octanol/water partition coefficients (P) was searched for structures closely related to the compound-of-interest. The most successful of these variations took the mean log P value of few most closely related compounds after each was adjusted for differences between their and the compound-of-interest's polarizabilities (α) and H-bond acceptor capacities (∑Ca).
A member of the hsp70 gene familyfrom the Mediterranean fruit fly, Ceratitis capitata

A gene from the Mediterranean fruit fly (Medfly) Ceratitis capitata, belonging to the hsp70 family of genes, has been cloned and characterized. This gene appears to be an example of a heat shock cognate (hsc) gene based on a variety of structural and functional criteria. The heat shock cognate genes serve critical roles in chaperoning of cellular proteins, and they are expressed in a more constitutive manner compared to the inducible heat shock genes. We determined the sequence of the entire coding region of this gene (designated Cerhsc1) together with 5′ and 3′ flanking regions. The coding region exhibits specific structural features that are characteristic of the subclass of heat shock genes producing proteins localized to the cytosol. The 5′ regulatory region of Cerhsc1 contains only the minimal array of canonical heat shock element sequences, a phenomenon commonly seen in heat shock cognates. Abundant transcripts are detected from this gene in adult tissue compared to the larval stage. In larval tissue, heat shock appears to produce only a slight increase in the level of transcripts detected. Based on overall structure and function, this Medfly gene appears to be an ortholog of heat shock cognate gene 4 (Drohsc4) of Drosophila melanogaster.
The impact of nonlinearity on degenerate parametric amplifiers

This work investigates the effects of system nonlinearities on degenerate parametric amplifiers. A simple, Duffing-type nonlinearity is appended to a representative equation of motion for a mechanical or electromechanical parametric amplifier, and classical perturbation methods are used to characterize the resulting effects on the amplifier’s frequency response and performance. Ultimately, the work demonstrates that parametric amplification can be realized in nonlinear, dynamic-range limited systems, such as resonant micro- or nanosystems, but at the expense of performance degradation. Additionally, it is shown that nonlinear amplifiers can be operated above their linear instability threshold but that doing so results in bistable amplified responses.
Approche semi-automatisée de conception de schémas multidimensionnels valides

Résumé. Cet article s’inscrit dans le cadre d’une approche semi-automatisée de conception de schémas multidimensionnels. Cette approche accepte des besoins OLAP, exprimés indépendamment de toute source OLTP, sous forme de tableaux n-dimensionnels, puis construit des schémas en étoile idéaux. En vue de valider ces étoiles idéales par rapport à une source d’alimentation, nous proposons d’une part, une méthode systématique pour effectuer la correspondance de chaque concept multidimensionnel avec la source et d’autre part, des règles de raffinement des étoiles. Les schémas en étoile valides seront ensuite fusionnés pour générer des schémas en constellation.
Node Disjoint Multipath Routing Approach for Controlling Congestion in Manets By Mr

Mobile Ad hoc Networks are highly dynamic networks. Quality of Service (QoS) routing in such networks is usually limited by the network breakage due to either node mobility or energy depletion of the mobile nodes. Node-disjoint routing becomes inessential technique in communication of packets among various nodes in networks. Meanwhile AODV (Ad Hoc On-demand Multipath Distance Vector) creates single-path route between a pair of source and destination nodes. Some researches has done so far to make multipath node-disjoint routing based on AODV protocol. But however their overhead and end-to-end delay are relatively high, while the detail of their code is not available too. In an ad hoc network, identification of all node-disjoint paths between a given pair of nodes is a challenging task. The phenomena that a protocol is not able to identify all node-disjoint paths that exist between a given pair of nodes is called path diminution. In this paper, we discuss that path diminution is unavoidable when a protocol discovers multiple node-disjoint paths in a single route discovery and working of node disjoint multipath protocol.
Air Guiding With Photonic Quasi-Crystal Fiber

We present and analyze a novel hollow-core photonic quasi-crystal fiber (HC-PQF) constructed with 12-fold quasi-periodic structure. The quasi-periodic cladding is shown in this letter to be able to guide light in a large-size hollow core. This HC-PQF provides two photonic bandgaps in the ¿/¿ < 1 region, thus two spectral windows of low loss guidance can be achieved. The behavior of guided modes that depends on the size of the defect core is studied, and the dispersion and confinement loss are also investigated. This research gives a physical insight into the propagation mechanism in HC-PQF and is crucial for future transmission applications.
Decentralized Linear Quadratic Gaussian control of multi-generator MVDC shipboard power system with Constant Power Loads

A major challenge in MVDC shipboard power systems is maintaining Medium Voltage DC (MVDC) system stability, due to the presence of the negative incremental resistance behavior of Constant Power Loads (CPLs). This paper presents a decentralized Linear Quadratic Gaussian (LQG) control approach for individual local generator side converter to regulate and stabilize the MVDC system. In this control approach, we model the non-linear CPL, which the decentralized controller is responsible for, as a virtual disturbance and consider it as an additional state to be estimated by Extended Local Kalman Filter (ELKF). Using the estimated virtual disturbance, the set-point trajectory in steady state can be obtained and applied in Linear Quadratic Regulator (LQR) with the optimal state feedback gain. Accordingly, linearization of the constant power load is achieved via this accurate estimation of the virtual disturbance; stability is guaranteed via an optimal LQR, as well as the load is shared among the generation units via droop control. Due to the fact that the estimation of each individual virtual disturbance is based only on the local measurements and the local fix model implemented in ELKF, the MVDC system adaptive set-point is achieved in local controllers without communication. This assumption holds true not only in the case of a sudden large load connection or disconnection, but also in case of generator loss.
Evaluation of an accelerometer for at-home monitoring of spontaneous activity in dogs.

OBJECTIVE To determine the correlation between activity as measured by an accelerometer and videographic measurements of movement and mobility in healthy dogs. ANIMALS 4 healthy dogs. PROCEDURES After determination that accelerometers had good agreement, 5 identical accelerometers were used simultaneously to test their output at 8 locations (rotated among collar, vest, and forelimb stocking locations) on each dog. Movement and mobility for each dog were recorded continuously with a computerized videography system for 7-hour sessions on 4 consecutive days. Accelerometer values were combined into 439 fifteen-minute intervals and compared with 3 videographic measurements of movement and mobility (distance traveled, time spent walking > 20 cm/s, and time spent changing position by > 12% of 2-dimensional surface area during 1.5 seconds). RESULTS 96% of values compared between the most discordant pair of accelerometers were within 2 SDs of the mean value from all 5 accelerometers. All mounting locations provided acceptable correlation with videographic measurements of movement and mobility, and the ventral portion of the collar was determined to be the most convenient location. CONCLUSIONS AND CLINICAL RELEVANCE Use of an accelerometer was adequate for at-home activity monitoring, an important end point in clinical trials of treatment for chronic disease, and provided information about daily activity that is unattainable by other methods.
Serum cystatin C as a marker of glomerular filtration rate.

Introduction Although widely used, serum creatinine is generally acknowledged to be an imperfect marker of glomerular ®ltration. More recently, the serum concentration of cystatin C has been measured as a potentially superior index of kidney function. However, at present, these assays are experimental and are not generally available. This paper will review published data on the utility of serum cystatin C in assessing the glomerular ®ltration rate (GFR) and consider whether determinations of cystatin C should become routine in clinical practice.
Framework for design and evaluation of complex interventions to improve health

Randomised controlled trials are widely accepted as the most reliable method of determining effectiveness, but most trials have evaluated the effects of a single intervention such as a drug. Recognition is increasing that other, non-pharmacological interventions should also be rigorously evaluated.1-3 This paper examines the design and execution of research required to address the additional problems resulting from evaluation of complex interventions—that is, those “made up of various interconnecting parts. ”4 The issues dealt with are discussed in a longer Medical Research Council paper (www.mrc.ac.uk/complex_packages.html). We focus on randomised trials but believe that this approach could be adapted to other designs when they are more appropriate. #### Summary points Complex interventions are those that include several components The evaluation of complex interventions is difficult because of problems of developing, identifying, documenting, and reproducing the intervention A phased approach to the development and evaluation of complex interventions is proposed to help researchers define clearly where they are in the research process Evaluation of complex interventions requires use of qualitative and quantitative evidence There are specific difficulties in defining, developing, documenting, and reproducing complex interventions that are subject to more variation than a drug. A typical example would be the design of a trial to evaluate the benefits of specialist stroke units. Such a trial would have to consider the expertise of various health professionals as well as investigations, drugs, treatment guidelines, and arrangements for discharge and follow up. Stroke units may also vary in terms of organisation, management, and skill mix. The active components of the stroke unit may be difficult to specify, making it difficult to replicate the intervention. The box gives other examples of complex interventions. #### Examples of complex interventions Service delivery and organisation: Stroke units Hospital at home Interventions directed at health professionals' behaviour: Strategies for implementing guidelines Computerised decision support Community interventions: Community …
The will to (de)liberate: shaping governable citizens through cognitive behavioural programmes in school

Lately, a deliberative conception of democracy has gained influence in policy debates throughout Europe. Individuals are here seen to be fostered into responsible, mature – democratic – citizens by being involved in dialogue. In the 1990s, calls for ‘democratic education’ intensified in Sweden. This article analyses two pedagogical models influenced by programmes developed in the USA that have recently had a great impact in Swedish schools and elsewhere, Social and Emotional Training and Aggression Replacement Training, both teaching pupils the ‘art of democratic deliberation’. By analysing manuals and interviews with school staff, we find that both models are based on the idea that through constant dialogue, pupils develop a ‘democratic mentality’. Referring to Foucault, this kind of dialogue can be seen as a technology of confession, where pupils are encouraged to reflect upon themselves and their behaviour, abilities and qualities as a way to change themselves and become democratic subjects.
Construct validation of distance run tests.

Abstract This study investigated the construct validity of distance run tests. A sample of 60 male college students were administered 10 running tests which ranged in distance from a 50-yd dash to the 2-mi run and the 12-min run. The factor analytic findings identified two robust factors. The first factor was associated with distance run tests of . 5 mi and longer. The second factor was essentially isolated by the 50- and 100-yd dashes. The shorter distance tests of 1 mi or less tended to yield complex factor structures, loading on both factors; whereas, the distances longer than 1 mi tended to be unidimensional and loaded almost exclusively on the distance run factor.
Building an “i-Learning” environment for entrepreneurial engineering

This paper presents an experimentation, realized within an International Master's, aimed to develop in tomorrow's engineers the entrepreneurial capabilities required to develop technology-intensive products and services in the domain of e-business. The new professional profile of the Entrepreneurial Engineer is introduced, along with the innovative features of an “i-learning” environment which supports the development of such profile. The interdisciplinarity, interactivity, immediacy, internetworking and individualization aspects of the environment are discussed with a particular focus on the curriculum design and the action learning strategy applied in the program.
FGFR4 signaling couples to Bim and not Bmf to discriminate subsets of alveolar rhabdomyosarcoma cells

Biological heterogeneity represents a major obstacle for cancer treatment. Therefore, characterization of treatment‐relevant tumor heterogeneity is necessary to develop more effective therapies in the future. Here, we uncovered population heterogeneity among PAX/FOXO1‐positive alveolar rhabdomyosarcoma by characterizing prosurvival networks initiated by FGFR4 signaling. We found that FGFR4 signaling rescues only subgroups of alveolar rhabdomyosarcoma cells from apoptosis induced by compounds targeting the IGF1R‐PI3K‐mTOR pathway. Differences in both proapoptotic machinery and FGFR4‐activated signaling are involved in the different behavior of the phenotypes. Proapoptotic stress induced by the kinase inhibitors is sensed by Bim/Bad in rescue cells and by Bmf in nonrescue cells. Anti‐apoptotic ERK1/2 signaling downstream of FGFR4 is long‐lasting in rescue and short‐termed in most non‐rescue cells. Gene expression analysis detected signatures specific for these two groups also in biopsy samples. The different cell phenotypes are present in different ratios in alveolar rhabdomyosarcoma tumors and can be identified by AP2β expression levels. Hence, inhibiting FGFR signaling might represent an important strategy to enhance efficacy of current RMS treatments.
On the Determination of Battery Energy Storage Capacity and Short-Term Power Dispatch of a Wind Farm

A methodology on the design of a wind farm battery energy storage system to realize power dispatchability is described. Based on the statistical long-term wind speed data captured at the farm, a dispatch strategy is proposed which allows the battery capacity to be determined so as to maximize a defined service lifetime/unit cost index of the energy storage system. Also, the application of the dispatch strategy is shown to yield the short-term wind farm output power schedule which meets the specified confidence level of power delivery commitment.
Sensitivity- and gradient-enhanced heteronuclear coupled/decoupled HSQC-TOCSY experiments for measuring long-range heteronuclear coupling constants.

A pulsed field gradient version of the sensitivity-enhanced 2D HSQC-TOCSY experiment is proposed for measurement of long-range heteronuclear coupling constants. The coupling constants are obtained by computer-aided analysis of mixed-phase multiplets with and without the heteronuclear splitting. Generation of pure phase data is not required. Since large 1JXH and JHH couplings are used for coherence transfer, small nJXH can be measured accurately, which could be difficult to obtain from purely heteronuclear polarization transfer experiments.
Elemental and intravenous total parenteral nutrition diet-induced gut barrier failure is intestinal site specific and can be prevented by feeding nonfermentable fiber

Objective Parenteral nutrition and elemental diets both cause bacterial translocation, immune dysfunction, and increased infection in laboratory animals, whereas elemental diets, with or without fiber, ameliorate some, but not all gut barrier failure. The purpose of this study is to investigate, in an Ussing chamber system, whether elemental vs. parenteral diets induce gut barrier failure in specific anatomical sites in the intestine and whether fiber can ameliorate this phenomenon. Design Controlled study in laboratory animals. Setting University laboratory. Subjects Male Sprague-Dawley rats. Interventions Nutritional support was provided to rats for 7 days by oral total parenteral nutrition (TPN; elemental diet) 307 kcal/kg/day, intravenous TPN (parenteral diet) 307 kcal/kg/day via jugular venous catheters, or rodent chow (controls). Measurements and Main Results Permeability to bacteria in intestinal segments of ileum, jejunum, and colon was evaluated in an Ussing chamber. Results were correlated with bacterial translocation to the mesenteric lymph nodes. Intravenous TPN caused greater bacterial translocation in all small intestinal segments and the cecum when compared with chow (p < .05). Oral TPN caused gut barrier failure only in the ileal segment, but not in the remainder of the small intestine (p < .001). Addition of cellulose provided a greater protection of the ileum to permeability than did pectin (p < .01). Conclusions TPN causes global intestinal barrier failure, but elemental diet prevents barrier failure in parts of the small intestine other than the ileum. The addition of cellulose fiber to elemental diet can ameliorate further barrier failure in the ileum.
A fast spectral/difference method without pole conditions for Poisson-type equations in cylindrical and spherical geometries

A simple and efficient FFT-based fast direct solver for Poisson-type equations on 3D cylindrical and spherical geometries is presented. The solver relies on the truncated Fourier series expansion, where the differential equations of Fourier coefficients are solved using second-order finite difference discretizations without pole conditions. Three different boundary conditions (Dirichlet, Neumann and Robin conditions) can be handled without substantial differences.
Teleworking adoption decision-making processes: Multinational and Malaysian firms comparison

Purpose – This paper aims at comparing teleworking adoption decision processes of multinational firms operating in Malaysia and Malaysian indigenous firms. It shows how to make comparative statistical analyses of teleworking adoption decision for the top managers of a firm.Design/methodology/approach – A total of 98 organizations (represented by the CEO or Director of Human Resource Division) furnished usable responses for this study, out of a total of 162 organizations registered with the Penang Development Corporation (the registrar of companies that participated in the survey). Findings – The results of statistical tests show that, in both multinational and Malaysia firms, the nature of work, organisational design, transportation problems, and relative advantage are important telework drivers. Availability of teleworking infrastructures is an important determinant of adoption in Malaysian firms but not in multinational firms, while workforce limitations have a strong influence on teleworking adoption in.
Optimal Portfolio Choices and the Determination of Housing Rents in the Context of Housing Price Uncertainty

This paper develops a utility indifference-based model to investigate the pricing issue of house rents under housing price uncertainty. Our model not only allows for the crucial features in the housing market, such as illiquidity, market incompleteness, and idiosyncratic property risks, but also the interaction of investors’ house tenure choices with their financial asset holdings. Our model provides interesting insights into the hedging of house resale risk and determination of housing rental prices. In addition to the parameters describing the expected changes and volatility on stock and house prices, we also show that the investors’ precautionary savings motive, idiosyncratic property risks, and the correlation between stock and housing price have important implication for the determination issue of housing rentals. We empirically test the model predictions using the data from major Asian markets and the results overall support the model predictions.