Miracle-dz/UniFAR-FTUs huggingface dataset:
The CLAS12 Spectrometer at Jeﬀerson Laboratory

75 The CEBAF Large Acceptance Spectrometer for operation at 12 GeV beam energy (CLAS12) in Hall B at Jeﬀerson Laboratory is used to study electro-induced nuclear and hadronic reactions. This spectrometer provides eﬃcient detection of charged and neutral particles over a large fraction of the full solid angle. CLAS12 has been part of the energy-doubling project of Jeﬀerson Lab’s Continuous Electron Beam Accelerator Facility, funded by the United States Department of Energy. An international collaboration of over 40 institutions contributed to the design and construction of detector hardware, developed the software packages for the simulation of complex event patterns, and commissioned the detector systems. CLAS12 is based on a dual-magnet system with a superconducting torus magnet that provides a largely azimuthal ﬁeld distribution that covers the forward polar angle range up to 35 ◦ , and a solenoid magnet and detector covering the polar angles from 35 ◦ to 125 ◦ with full azimuthal coverage. Trajectory reconstruction in the forward direction using drift chambers and in the central direction using a vertex tracker results in momentum resolutions of < 1% and < 3%, respectively. Cherenkov counters, time-of-ﬂight scintillators, and electromagnetic calorimeters provide good particle identiﬁcation. Fast triggering and high data-acquisition rates allow operation at a luminosity of 10 35 cm − 2 s − 1 . These capabilities are being used in a broad program to study the structure and interactions of nucleons, nuclei, and mesons, using polarized and unpolarized electron beams and targets for beam energies up to 11 GeV. This paper gives a general description of the design, construction, and performance of CLAS12. the 5% level and required charged tracks in the FTOF and ECAL in opposite FD sectors. Finally, several other triggers were used for monitoring purposes and were heavily pre-scaled.
COMPARISON OF PI3K/AKT/

Background The phosphatidylinositol 3-kinase (PI3K)/Akt/ mechanistic target of rapamycin (mTOR) pathway plays a significant role in both tumorigenesis and progression of disease in non-small cell lung cancer (NSCLC). 1 Increased activation of the pathway, whether in tumor or immune cells, results in an immunosuppressive tumor microenvironment. 2 Therefore, we looked into how this pathway differs in three distinct NSCLC immune phenotypes
The impact of antiretroviral therapy in a cohort of HIV infected patients going in and out of the county jail.

Background: Jails are an important venue of HIV care and a place for identification, treatment and referral for care. HIV infected inmates in the San Francisco County jail are offered antiretroviral treatment (ART), which many take only while in jail. We evaluated the effect of ART administration in a cohort of jail inmates going in and out of jail over a nine year period. Methodology/PrincipalFindings: In this retrospective study, we examined inmates with HIV going in and out of jail. Inmates were categorized by patterns of ART use: continuous ART - ART both in and out of jail, intermittent ART - ART only in jail; never on ART - eligible by national guidelines, but refused ART. CD4 and HIV viral load (VL) were compared over time in these groups. Over a 9 year period, 512 inmates were studied: 388 (76%) on intermittent ART, 79 (15%) on continuous ART and 45(9%) never-on ART. In a linear mixed model analysis, inmates on intermittent ART were 1.43; 95%CI (1.03, 1.99) times and those never on ART were 2.89; 95%CI (1.71, 4.87) times more likely to have higher VL than inmates on continuous ART. Furthermore, Inmates on intermittent ART and never-on ART lost 1.60; 95%CI (1.06, 2.13) and 1.97; 95%CI (0.96, 3.00) more CD4 cells per month, respectively, compared to continuously treated inmates. The continuous ART inmates gained 0.67CD4 cells/month. Conclusions/Significance: Continuous ART therapy in jail inmate’s benefits CD4 cell counts and control of VL especially compared to those who never took ART. Although jail inmates on intermittent ART were more likely to lose CD4 cells and experience higher VL over time than those on continuous ART, CD4 cell loss was slower in these inmates as compared to inmates never on ART. Further studies are needed to evaluate whether or not intermittent ART provides some benefit in outcome if continuous ART is not possible or likely. a natural of a large cohort of
Prediction Modeling of Software Startup Success By PLS-SEM Approach

With the fact that the tendency of startup business fail, it is necessary to understand factor influencing the startup success. It is understood that the lack of knowledge of how to start business creates uncertainty. The uncertainty may increase the likelihood of startup failure, which leads to economic loss. This paper aims to develop a predictive model of startup success in identifying factors and variables influencing startup success. This study also explores ways to compile and validate predefined startup prediction models in the startup business environment. Furthermore, the significance of factors and variables have also been identified to predict software startup success. The results showed that there were 18 significant factors influencing software startup success. These include the characteristics of the founders, quality of the startup organizations, support of resources, environmental conditions, performance of value creation processes, and effectiveness of competitive strategies. The result also showed that six variables contributed significantly (74.8%) in the prediction of software startup success.
THE CAPABILITY OF THE EMERGENCY MEDICAL STAFF MEMBERS AND DOCTORS TO TAKE PATIENTS’ MEDICAL HISTORY

: Objective: The key point to detect patients’ need in pre-hospital emergency is to have high ability to take medical history. All research findings show that this ability is low. The objective of this research is to investigate the ability to take medical history of patients in the Emergency department of Mayo Hospital Lahore. Methods: This research was a descriptive cross-sectional study conducted from April 2019 to April 2020. The population included staff and doctors (N=171). The samples were selected using multi-stage cluster sampling. Data were collected by a researcher-developed questionnaire. The collected data were analyzed by SPSS software version 16 conducting descriptive and inferential statistics. All tests were administered at a significance level of P less than 0.05. Results: One hundred sixty-five (96.5%) participants were male. The mean score of the ability to take medical history was 58.4±11.1. Therefore, 95 participants (58.3 %) had poor ability and 64 participants (39.3 %) owned moderate ability. The highest score concerning the ability to take medical history was for the aspect of professional knowledge (mean rank=5). The most influential aspect in the ability was respectively for ‘professional knowledge’ (P=0.0001, Beta=0.509). Pearson correlation coefficient indicated a relationship (r=-0.149, P=0.05) between the ability to take medical history and age. Conclusion: The results of the current study indicated that the ability to take medical history among the staff and doctors was low. Therefore, a thorough review of trainings promoting personnel’s professional knowledge is urgently required.
Delayed stress ﬁber formation mediates pulmonary myoﬁbroblast differentiation in response to TGF- (cid:1)

Delayed stress ﬁber formation mediates pulmonary differentiation in response to TGF- (cid:1) differentiation induced by transforming growth factor- (cid:1) (TGF- (cid:1) ) and characterized by de novo expression of smooth muscle (SM)-speciﬁc proteins is a key process in wound healing and in the pathogenesis of ﬁbrosis. We have previously shown that TGF- (cid:1) -induced expression and activation of serum response factor (SRF) is required for this process. In this study, we examined the signaling mechanism for SRF activation by TGF- (cid:1) as it relates to pulmonary myoﬁbroblast differentiation. TGF- (cid:1) stimulated a profound, but delayed (18–24 h), activation of Rho kinase and formation of actin stress ﬁbers, which paralleled SM (cid:2) -actin expression. The translational inhibitor cycloheximide blocked these processes without affecting Smad-dependent gene transcription. Inhibition of Rho kinase by Y-27632 or depolymerization of actin by latrunculin B resulted in inhibition TGF- (cid:1) -induced SRF activation and SM (cid:2) -actin expression, having no effect on Smad signaling. Conversely, stabilization of actin stress ﬁbers by jasplakinolide was sufﬁcient to drive these processes in the absence of TGF- (cid:1) . TGF- (cid:1) promoted a delayed nuclear accumulation of the SRF coactivator megakaryoblastic leukemia-1 (MKL1)/myocardin-related transcription factor-A, which was inhibited by latrunculin B. Furthermore, TGF- (cid:1) also induced MKL1 expression, which was inhibited by latrunculin B, by SRF inhibitor CCG-1423, or by SRF knockdown. Together, these data suggest a triphasic model for myoﬁbroblast differentiation in response to TGF- (cid:1) that involves 1 ) initial Smad-dependent expression of intermediate signaling molecules driving Rho activation and stress ﬁber formation, 2 ) nuclear accumulation of MKL1 and activation of SRF as a result of actin polymerization, and 3 ) SRF-dependent expression of MKL1, driving further myoﬁbroblast differentiation.
Internet of things for automatic garage doors using ESP8266 module

The purpose of this study is to design garbage door gaters by utilizing the technology of the Internet of Things (IoT) by using the control of microcontroller. The methodology used in this research is the design of prototype by following the stages and procedures of Research and Development. Making the control system is done through three stages, namely: software design, hardware manufacture, and integration of software and hardware. The software created includes a motion control program through the control of the microcontroller ESP8266 module connected to Arduino Nodemcu. ESP8266 will get orders from smartphones that have been installed android garage door controllers. The design results show that the design of Automatic Garage Doors designed miniature can be used effectively to perform the task up to a distance of ± 100s.
DNAprobesfor the rapid identi¢cationofmedically important

Recently, a new flow cytometric technology to detect multiple DNA target sequences in a single microtiter well plate was developed [multianalyte profiling (MAP) System, Luminex Corp., Austin, TX]. DNA probes, directed to the internal transcribed spacer 2 region of ribosomal DNA, were therefore designed to detect and differentiate PCR amplicons from six medically important Candida species using this system. Each probe was covalently linked to one of 100 available microsphere (bead) sets. Biotinylated PCR amplicons were then hybridized to the complementary probe on each bead set. Bound amplicons were detected fluorometrically using a streptavidin-linked reporter dye, R-phycoerythrin. Specific hybridization was noted for all six Candida species probes (mean sample-tobackground ratio standard error: Candida albicans, 58.7 1.2; Candida tropicalis, 53.2 3.8; Candida glabrata, 46.9 2.1; Candida parapsilosis, 59.9 1.6; Candida krusei, 54.7 3.7 vs. 0.9 0.03 for all heterologous Candida species DNA targets and vs. 1.0 0.1 for samples containing water instead of DNA; Po 0.001). The limit of test sensitivity was 0.5 pg of DNA. A sample could be processed and analyzed within 1 h post-PCR amplification. Therefore, the multianalyte profiling system was rapid, sensitive and specific for the detection and differentiation of the most medically important species of Candida.
Rapid Method for Detecting

Fig. 1. Subtyping strains of hepatitis C virus. Hepatitis C virus ANA of different subtypes (provided by Innogenetics) was amplified with the Roche Amplicor HCV kit. Denatured amplicons (50 L) were hybridized to membrane-bound probes at 46’C as outlined in the Info LIPa HCV kit manual.The accompanying scheme for subtyping Is shown on the right. Subtype la refers to the original HCV US isolate (HCV-1) and Isolates HCV-H and HC-J1. Subtype lb comprises isolates HCV-J, HCV-BK, HCV-T,HCV-JK1, HC-J4, HCV-TA.HCV-JT,and HCV-China. HCV type 2a is represented by isolate HC-J6, type 2b by isolate HC-J8. Subtype 3a includes isolates E-bl, Ta, BR33, BR36, and HDIO; subtype 3b, Tb and HCV-TR. Isolates similar to Z5 and Z6 and EG-16 and -33 can be detected as type 4, and isolates similar to SAl, 3, 7, and 11 can be classified as type 5.
Role of Human Development and Governance in Foreign Direct Investment in the Post Reform Era: The Case of Tanzania

 ABSTRACT Along with Sub-Saharan Africa (SSA), Tanzania also went through “lost decades” and started reviving its growth in the early 2000s; partly because of a relatively outward looking trade policy started in the mid-1980s, and improved foreign direct investment (FDI) inflows that grew nearly six-fold over the past decade. The largest inflows of FDI in the recent years are either in sectors with comparative advantage, such as, natural resources and agriculture or where there is need for investment, and returns are high– for example, manufacturing sector. Either developed countries or developing countries from SSA are important source of FDI in Tanzania, which next may focus to attract more FDI from emerging economies such as China, India, and Malaysia as her neighbors have done. The estimation results obtained from Auto regressive distributed lag (ARDL) approach of cointegration for annual time series data for the period of 1988 to 2013 suggest that there is, for instance, a link between FDI and educations indicating better education achievements help absorb the benefits of FDI better. Other important determinant of FDI inflows, based on our dynamic model analysis are GDP growth and labor force growth. Contrary to the perceived view, Tanzania seems unable to take the advantage of trade reform on FDI inflows. The results also suggest the natural resources rent has a positive impact only in the
A Computationally Inexpensive Way to Detect and Perform Segmentation on Morphed Images Using CNN

In the last few years, the amount of image data generated by the use of image (and video) processing software such as GNU Gimp, Adobe Photoshop has increased enormously as social networking sites such as Facebook and Instagram have come into force. Such photos are key sources of fake news to propagate radical ideologies, swing public opinion and misused for incitement by the crowd. Being able to solve such a problem and integrating that solution to the social media websites might be able to save the people from becoming a victim of mis-information and propaganda. In this paper we propose a way to detect tampered/morphed images on social media and generate a binary mask of the tampered region using computationally inexpensive pre-processing algorithms and convolutional neural networks.
Determination of the spin triplet p (cid:2) scattering length from the ﬁnal state interaction in the (cid:2) p p → pK + (cid:2) reaction

The (cid:2) pp → pK + (cid:2) reaction has been measured with the COSY-TOF detector at a beam momentum of 2 . 7GeV /c . The polarized proton beam enables the measurement of the beam analyzing power by the asymmetry of the produced kaon ( A KN ). This observable allows the p(cid:2) spin triplet scattering length to be extracted for the ﬁrst time model independently from the ﬁnal state interaction in the reaction. The obtained value is a t = ( − 2 . 55 + 0 . 72 − 1 . 39stat . ± 0 . 6 syst . ± 0 . 3 theo . )fm. This value is compatible with theoretical predictions and results from model-dependent analyses.
Conflicts and Social Capital in Organizations Conflicts and Social Capital Organizations

Social capital (SC) is a comprehensive concept, which refers to benefits derived from social interaction. In organizations, SC can be divided into 3 levels: personal SC, which refers to the benefits the individual receives from personal social connections, inside and outside the organization; intraorganizational SC, which refers to the benefits derived from good relationships within organizational units, and the organization as a whole; and external SC, which refers to the profits derived from interfaces of role holders, such as the CEO, with stakeholders. Organizational SC and conflicts in an organization are ostensibly very different in nature, whereas SC is an intangible that fits the positive psy chology domain; conflicts are usually unwanted occurrences in organizations. Scholars noted that conflicts affect employee ’ s SC and usually reduce it, but the opposite was hardly investigated. This chapter examines how and why the conversion of social rela - tionships into capital can result in conflicts at all organizational SC levels. To do this, the interface between the levels of SC in organizations and types of conflicts was examined. In conclusion, developing “C-type” conflicts, which are desirable conflicts, and avoiding “A-type” conflicts, which are destructive conflicts, depend on a good match between the different organizational SC levels.
Institutional Knowledge at Singapore Management University Institutional Knowledge at Singapore Management University Efficient representative subset selection over sliding windows Efficient representative subset selection over sliding windows

—Representative subset selection (RSS) is an important tool for users to draw insights from massive datasets. Existing literature models RSS as the submodular maximization problem to capture the “diminishing returns” property of the representativeness of selected subsets, but often only has a single constraint (e.g., cardinality), which limits its applications in many real-world problems. To capture the data recency issue and support different types of constraints, we formulate dynamic RSS in data streams as maximizing submodular functions subject to general d -knapsack constraints (SMDK) over sliding windows. We propose a K NAP W INDOW framework (KW) for SMDK. KW utilizes the K NAP S TREAM algorithm (KS) for SMDK in append-only streams as a subroutine. It maintains a sequence of checkpoints and KS instances over the sliding window. Theoretically, KW is 1 − ε 1+ d -approximate for SMDK. Furthermore, we propose a K NAP W INDOW P LUS framework (KW + ) to improve upon KW. KW + builds an index S UB K NAP C HK to manage the checkpoints and KS instances. S UB K NAP C HK deletes a checkpoint whenever it can be approximated by its successors. By keeping much fewer checkpoints, KW + achieves higher efﬁciency than KW while still guaranteeing a 1 − ε (cid:48) 2+2 d -approximate solution for SMDK. Finally, we evaluate the efﬁciency and solution quality of KW and KW + in real-world datasets. The experimental results demonstrate that KW achieves more than two orders of magnitude speedups over the batch baseline and preserves high-quality solutions for SMDK over sliding windows. KW + further runs 5-10 times faster than KW while providing solutions with equivalent or even better utilities.
In-Silico Pharmacokinetics Study on the Inhibitory Potentials of the C=O Derivative of Gedunin and Pyrimethamine against the Plasmodium falciparum Dihydrofolate Reductase; A Comparative Study

Background: Malaria is a life-threatening disease caused by parasites that are transmitted to people by mosquitoes. An estimated 700,000 people were killed by malaria in 2010 globally and approximately half the world’s population are at risk of the disease. Malaria is preventable and curable. Malaria is caused by a microscopic parasite called Plasmodium. Four species of this parasite infect humans to cause malaria but Plasmodium falciparum is the most deadly. Plasmodium is transmitted between people by blood-eating mosquitoes. Pyrimethamine is an antiparasitic medicine that helps prevent parasites from growing and reproducing in the body. Materials and Methods: The C=O derivative of gedunin was designed using the ChemAxon software where the methyl group attachment of gedunin was substituted for the C=O group and converted into an mrv file. The mrv file was converted into SMILES strings for the purpose of docking using the Open Babel software. The AutoDock Vina software was utilized for the molecular docking process and the in-silico pharmacokinetics parameters of the C=O derivative of gedunin was predicted using the SwissADME server. Results: Results from the physiochemical characteristics prediction of the Plasmodium falciparum DHFR showed that the half life of the enzyme in human reticulocytes can be estimated at 30 hours when subjected to an in vitro study. The in silico pharmacokinetics study also showed that both the C=O derivative of gedunin and pyrimethamine violated none of the lipinski’s rule. Results from the molecular docking study of the compounds (C=O derivative of gedunin and pyrimethamine) against the Plasmodium falciparum DHFR were -9.0 and -8.0Kcal/mol respectively. Conclusion: The above results showed that both experimental compounds can be safe for oral administration haven satisfied the lipinski’s rule requirements. The molecular docking study also showed that the C=O derivative of gedunin might be a better antimalarial agent by its exhibition of a higher binding energy against the Plasmodium falciparum DHFR.
Entrepreneurship with Social Responsibility Entrepreneurship with Social Responsibility

Since the second half of the twentieth century, the society’s thinking about the behav- ior of companies has gradually begun to change. Companies are expected to use their power and finances to influence life around themselves, especially their quality. The cor - porate social responsibility (CSR) concept is a very progressive management approach that focuses on long-term goals and long-term returns. CSR seeks to harmonize relation- ships with stakeholders, which the company identifies and implements activities that go beyond legal and ethical standards. A socially responsible company performs something extra volunteer, conducts dialog with its stakeholders, and invests in improving relationships. The Department of Economics of the University of Žilina conducted a marketing survey entitled “Perceptions of Corporate Social Responsibility and its Communication by Companies”. The survey was conducted to find out how companies in Slovakia use the CSR concept and what is the level of their communication about this concept in relation to the external environment. Anonymous questionnaire method was used to obtain this data. The method of induction and deduction was used to process the obtained data and the phenomena investigated and to generalize and produce conclusions. Mathematical and statistical methods were used to evaluate survey data, and the synthesis method was used to create recommendations for companies.