Miracle-dz/UniFAR-FTUs huggingface dataset:
Randomized controlled , double blind study on the effects of heliox in cardiopulmonary performance and in peripheral muscle oxygenation during exercise in CPOD patients View project

Reproducibility of frequency content from surface electromyography (sEMG) signals has not been assessed and it is unknown if incremental load testing design could affect sEMG in cycling. The goals of this study were to assess the reproducibility of measures from sEMG frequency content between sessions and to compare these frequency components between a ramp and a step incremental cycling test. Eighteen cyclists performed four incremental load cycling tests to exhaustion. Two tests were performed using a step increment (load started at 100 W for 3 min followed by increments of 30 W every 3 min) and two were performed using a ramp increment (load started at 100 W for 1 min followed by increments of 30 W·min). sEMG was monitored bilaterally for the rectus femoris and vastus lateralis throughout the tests and converted into overall activation (whole signal bandwidth), highand lowfrequency contents. The reproducibility of the frequency content ranged from none to strong (ICC = 0.07–0.90). Vastus lateralis activation was larger at the step compared to the ramp test (P < 0.01), without differences for rectus femoris (P = 0.22–0.91) and for the high-frequency (P = 0.28–0.95) and low-frequency contents (P = 0.13–0.94). sEMG from vastus lateralis and rectus femoris presented none to strong reproducibility. Vastus lateralis is more activated in step test design. ARTICLE HISTORY Accepted 5 April 2017
Self‐directed student research through analysis of microarray datasets: A computer‐based functional genomics practical class for masters‐level students

This report describes a linked series of Masters‐level computer practical workshops. They comprise an advanced functional genomics investigation, based upon analysis of a microarray dataset probing yeast DNA damage responses. The workshops require the students to analyse highly complex transcriptomics datasets, and were designed to stimulate active learning through experience of current research methods in bioinformatics and functional genomics. They seek to closely mimic a realistic research environment, and require the students first to propose research hypotheses, then test those hypotheses using specific sections of the microarray dataset. The complexity of the microarray data provides students with the freedom to propose their own unique hypotheses, tested using appropriate sections of the microarray data. This research latitude was highly regarded by students and is a strength of this practical. In addition, the focus on DNA damage by radiation and mutagenic chemicals allows them to place their results in a human medical context, and successfully sparks broad interest in the subject material. In evaluation, 79% of students scored the practical workshops on a five‐point scale as 4 or 5 (totally effective) for student learning. More broadly, the general use of microarray data as a “student research playground” is also discussed. BIOCHEMISTRY AND MOLECULAR BIOLOGY EDUCATION Vol. 39, No. 6, pp. 440–447, 2011
Molecular resonances in the Rydberg-excitation spectrum of an ultracold Cs gas

This thesis is devoted to studies of Rydberg states of Cs generated in dense (density > 10 cm ) ultracold (T 40μK) gas-phase samples by photoexcitation with narrow-bandwidth laser radiation and millimetre waves. The emphasis is on systematic investigations of the interactions of the Rydberg atoms with their environment, be it other Rydberg atoms or ground-state atoms located in their vicinity, or external electric and magnetic elds. These interactions and their e ects on the Rydberg atoms are studied by high-resolution spectroscopy and manifest themselves as level shifts, line broadenings and, most importantly, by the appearance of additional lines in the Rydberg-excitation spectrum of Cs that can be attributed to the formation of highly excited Cs2 molecules. At the positions of these resonances, the ultracold atoms are transferred into bound states by the narrow-bandwidth radiation, in a process known as photoassociation. Metastable molecules are formed, which eventually decay by ionisation, dissociation or the emission of a photon. Depending on the intensity, the frequency and the temporal shape of the photoexcitation radiation pulses used in the experimental studies, very di erent families of molecular states could be produced: i) Molecular states in which one Cs Rydberg atom is bound to a ground-state Cs atom by the low-energy scattering of the Rydberg electron o the ground-state atom. The contribution made to the understanding of these states in the realm of this thesis was the experimental discovery of the importance of the singlet scattering channels next to the triplet scattering channels. ii) Molecular states in which one Cs Rydberg atom interacts with another Cs Rydberg atom through long-range electrostatic interactions. Here, the main contributions made in the realm of this thesis were iia) the experimental discovery of molecular resonances caused by the dipole-quadrupole interaction, which violates the electronic parity of the Rydberg-atom dimer, iib) the unambiguous identi cation of the contributions of terms as high as the octupole-octupole interaction to the spectral signatures of the Rydberg-atom dimer, and iic) the investigation of diverse dynamical phenomena such as Penning ionisation of the dimer, the aggregation of several Rydberg atoms by intentionally catalysing the excitation process, and the spontaneous ionisation of the entire Rydberg-atom sample induced by the long-range interactions. A prerequisite to a careful study of interactions between Rydberg atoms is a de-
2 Topical Prescription Agents 10 . 2 . 1 Topical Corticosteroids

Atopic dermatitis frequently requires the use of over-the-counter and prescription medications for effective management. Emollients and topical corticosteroids are effective for most patients and are the most commonly utilized agents by experienced dermatologists. Antihistamines, antibiotics, and calcineurin inhibitors may also prove helpful in the correct clinical scenarios. Severe atopic dermatitis, however, can be difficult to manage and not infrequently require substantial immunomodulatory medications. Targeted molecular therapies, such as dupilumab, are promising, emerging atopic dermatitis therapies. The medication pearls reviewed in this chapter will assist providers in managing atopic dermatitis patients.
Formula 12 ® ) containing a non-reducing disaccharide and an enzymatic agent 2

31 There are no reports of saccharolytic enzymes being used in the preparation of formulations for 32 animal semen extenders. In the present study, the authors evaluated the performance of an 33 innovative semen extender (Formula12) in the long-term liquid storage of boar semen at 17°C. 34 The formulation used a disaccharide (sucrose) as the energy source precursor coupled to an 35 enzymatic agent (invertase). The innovative extender was evaluated and compared in vitro to a 36 commercial extender (Vitasem LD) for the following variables: Total Motility (TM), Forward 37 Progressive Motility (FPM), spermatozoa morphology, membrane integrity, acrosome integrity, and 38 sperm chromatin instability. Boar sperm diluted in Formula12 and stored for 12 days at 17°C 39 maintained a commercially acceptable level of FPM (>70%). Following the results in vitro, an AI 40 field trial was performed. A total of 170 females were bred (135 with Formula12 and 35 with 41 Vitasem LD). The pregnancy rates were 97.80% vs 91.43%, and the farrowing rates were 96.30% 42
Oesophageal atresia: a 10-year experience of a Paediatric Intensive Care Unit

Background/Purpose: Oesophageal atresia (OA) is a congenital malformation with a variable prognosis. The aims were to establish OA’s incidence in the central region, to characterize infants with OA admitted and to compare its clinical outcome after surgical repair, according to OA classifi cation. Methods: A retrospective review of infants with OA admitted to a PICU, after surgical repair, between 2002 and 2011. Patient characteristics, OA’s classifi cation, surgery, morbidity and mortality were analyzed. Two groups were compared according to OA classifi cation. Results: Thirty-four infants were admitted, out of which 65% were male, with a median gestational age of 36 weeks and birth weight of 2310g. Nineteen of them presented other malformations, mainly cardiac. Nine cases were classifi ed as long-gap OA. Fistula ligation and primary oesophageal anastomosis was the most common surgical option (n=27). Early complications occurred in 13 infants (38%), mostly anastomotic leak, and were similar according to gap length (p=0.704). PICU stay and mechanical ventilation were longer in long-gap OA patients (p=0.009 and p<0.001 respectively) and in infants with other malformations (p=0.027 and p=0.003 respectively). There was no mortality. Conclusions: The frequency of OA associated malformations implies a systematic screening of these patients. Gap length and presence of associated malformations were the major determinants of length of intensive care stay and ventilation days in OA patients.
Strategies of Diversification and Brand Extension in SME Food Companies: Which Factors Might Affect the Impact of Consumers’ Preferences

The purpose of the research is to evaluate the brand extension strategy of SMEs food companies, through the analysis of the consumers' response. The research analysed the case study of a food processing cooperative, “Gruppo Grifo Agroalimentare”, which diversified its production through the acquisition of new SMEs companies. Through an hypothetical brand extension of the products, the goal is to study which factors would affect the acceptance and the purchasing of the extension. The results drive allow the SMEs food companies to know the needs of new consumers and to be able to meet these needs, both in terms of distribution and in terms of offer.
dysregulation Staphylococcal enterotoxins stimulate lymphoma-associated immune

http://classic.bloodjournal. org/content/124/5/761.full. html Updated information and services can be found at: (1839 articles) Lymphoid Neoplasia Articles on similar topics can be found in the following Blood collections http://www.bloodjournal. org/site/misc/rights.xhtml#repub_requests Information about reproducing this article in parts or in its entirety may be found online at: http://www.bloodjournal. org/site/misc/rights.xhtml#reprints Information about ordering reprints may be found online at: http://www.bloodjournal. org/site/subscriptions/index.xhtml Information about subscriptions and ASH membership may be found online at:
Analysis of Salvia miltiorrhiza (Danshen)

Danshen is one of the most popular traditional Chinese medicines (TCMs) in China. In recent years, people become increasingly aware of the value of Danshen, which is attracting global attention. Modern researches indicate that phenolic acids and tanshinones are the main chemical components related to the bioactivities and pharmacological properties of Danshen. Because of the diversity of the chemical structures and characters of these components, an analytical method of Danshen varies, including GC–MS, HPLC–DAD–MS, and so on. Besides that, the development of the analytical technology makes the quality control of Danshen more effective and reliable. Quality evaluation is from single or several components analysis to fingerprint, or in combination. In this paper, much attention was paid to introducing the methods developed for the isolation of major compounds from Danshen and identification of the chemical components of Danshen. Key words: Salvia miltiorrhiza (Danshen), water-soluble compounds, lipophilic compounds, isolation, quantitative analysis, fingerprint.
Learning autonomous vehicle passengers’ preferred driving styles using g-g plots and haptic feedback

In this work, we present and experimentally test a framework for learning an autonomous vehicle passenger’s preferred driving style. The study is performed with N = 3 human subjects in a vehicle simulator that consists of a 3-DOF motion simulator, providing feelings of longitudinal and lateral acceleration to the passenger, an automatically controlled steering wheel, providing information about the steering controller behavior, and a computer monitor, providing a virtual rendering of the view through the windshield. The vehicle controller is designed to track speeds while satisfying limits on the maximum allowable longitudinal and lateral accelerations. These accelerations are related to the passenger’s preferences and are represented as a surface on a g-g plot. The passenger’s preferences are learned from comfort labels provided by the passenger, which correspond to positive and negative assessments of the vehicle’s current driving behavior. In the framework that we present, these labels directly change the corresponding parametrization of the g-g plot, thereby modifying the limiting constraints to be enforced by the controller on-line, which leads to a change in the behavior of the vehicle. The collected data supports the hypothesis that there is a personalized driving style preference, and also shows that our proposed preference-learning scheme converges to a preferred driving style.
Meta-Analysis of Therapy in HFpEF Effects of Treatment on Exercise Tolerance , Cardiac Function , and Mortality in Heart Failure With Preserved Ejection Fraction

Accreditation and Designation Statement The American College of Cardiology Foundation (ACCF) is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians. The American College of Cardiology designates the educational activities in JACC for a maximum of 1 AMA PRA Category 1 redit. Physicians should only claim credit commensurate with the xtent of their participation in the activity.
Problematising Adult Basic and Secondary Education in a Globalised World: From second chance to school recovery

The article problematises the role Adult Basic and Secondary Education (ABSE) plays in response to global challenges, under the influence of global policy. Drawing on a three-year study that assumed a social realism perspective and employed situational analysis, it discusses three dimensions of policy making in adult education: the scales of political mobilisation, the environments for policy-making, and the meanings conveyed. In doing so, it argues that although the perceptions and reception of as well as influence on international policy vary across countries, ABSE has turned today into a school-recovery opportunity for the younger generations who failed in school and people whose educational achievements in a given country are not recognised when migrating to a new one. This calls into question both the way policy in ABSE sees the social problem at stake and how policy solutions in this area of public intervention impinge on broader issues of (in)equality in education.
Interlaboratory comparability - an important criterion for selection of a method for relative quantifi cation of BCR-ABL

SUMMARY Objective: A BCR-ABL fusion transcript found in peripheral blood or bone marrow is a specifi c molecular marker of chronic myeloid leukemia and Philadelphia chromosome – positive acute lymphoblastic leukemia. Modern quantitative analyses in molecular biology are based on real-time PCR technology and fl uorescent probes targeted to a complementary part of DNA/cDNA templates. A current trend in laboratory medicine and applied molecular biology is to support profi ciency testing and transferability of results of quantitative PCR analyses. The goal of the study is to compare the diagnostic impact of two used systems for BCR-ABL quantifi cation with respect to recommendations of the Europe Against Cancer Program (EAC) unifying the used BCR-ABL methodology. Material and Methods: A total of 143 peripheral blood specimens and 5 bone marrow aspirates from 80 adult subjects were analysed. Two quantitative procedures were simultaneously examined. Procedure I was based on Superscript III reverse transcription (Invitrogen) and M-bcr FusionQuant Kit (Ipsogen) for relative quantifi cation of BCR-ABL. In procedure II we used LightCycler t(9;22) Quantifi cation Kit (Roche). Results: The calibration curve for BCR-ABL gene (FusionQuant) was: CT = -3.54 . log(conc BCR-ABL) + 42.33; automatic threshold = 0.06, correlation coeffi cient (r) = -1.00, reaction effi ciency = 92%. The Roche kit does not use any calibration process for BCR-ABL. The calibration curve for ABL gene (FusionQuant) was CT = -3.53 . log(conc ABL) + 40.91, ABL threshold = 0.08, r = -1.00, reaction effi ciency = 91%. The calibration curve for G6PDH control gene (Roche) was CT = -3.2 . log(conc G6PDH) + 30.9, r = -1.00, reaction effi ciency = 100%. The limit of quantifi cation for BCR-ABL (FusionQuant) was 10 copies in 5 μl of the used cDNA. The lowest relative concentration of BCR-ABL detectable by the Roche assay was 0.001 %. The experimental data showed a close linear association in relative quantity of BCR-ABL received by the examined assays with r = 0.77, P < 0.001. Conclusions: The principal difference between the tested procedures is the house-keeping gene used for normalization of BCR-ABL quantity. In agreement with the Europe Against Cancer strategy we have selected ABL gene as a normalization gene for our lab.
Validity of the ActiGraph GT 3 X + and BodyMedia SenseWear Armband to estimate energy expenditure during physical activity and sport Running Head : Validity of the ActiGraph GT 3 X + and BodyMedia Armband to predict energy expenditure

Objective: The purpose of this study was to assess the validity of the ActiGraph GT3X+ (GT3X+) and the BodyMedia SenseWear Armband (SWA) to estimate energy expenditure (EE) during physical activity and field sport movements. Design: Criterion validity. Methods: Twenty-six active adults completed a single 90 min session involving alternating intervals of exercise (5 min) and recovery (10 min). Exercise involved walking (4 km/h), jogging (8 km/h), running (12 km/h) or a sport-simulated circuit (three intervals). Participants wore two triaxial
Effect of Bait Type and Bait Size on Catch Efficiency in the European Hake Merluccius merluccius Longline Fishery

We thank the crew of the Spanish longline vessel Anxuela for their valuable help during the cruise as well as the ship owners for allowing us to participate in the cruise. We also thank Manuel Bermudez from the Spanish Fisheries Technology Center (CETPEC; Celeiro, Spain) for his assistance in arranging the sea trials. We are grateful to Mustad Longline AS and the Norwegian Research Council (Brukerstyrt Innovasjonsarena [BIA] Project Number 210871/O30) for funding this study.
Regional Metabolic Changes in the Hippocampus and Posterior Cingulate Area Detected with 3-Tesla Magnetic Resonance Spectroscopy in Patients with Mild Cognitive Impairment and Alzheimer Disease

http://acr.sagepub. com/content/50/3/312 The online version of this article can be found at: DOI: 10.1080/02841850802709219 2009 50: 312 Acta Radiol Zhiqun Wang, Cheng Zhao, Lei Yu, Weidong Zhou and Kuncheng Li magnetic resonance spectroscopy in patients with mild cognitive impairment and alzheimer disease Regional metabolic changes in the hippocampus and posterior cingulate area detected with 3-Tesla
DEPOSITION ON SHEAR WAVE SPEED RECONSTRUCTION IN HUMAN LIVER

A Biome 90281, C intellec of this Abstract—Shear wave elasticity imaging (SWEI) has found success in liver fibrosis staging. This work evaluates hepatic SWEI measurement success as a function of push pulse energy using two mechanical index (MI) values (1.6 and 2.2) over a range of pulse durations. Shear wave speed (SWS) was measured in the livers of 26 study subjects with known or potential chronic liver diseases. Each measurement consisted of eight SWEI sequences, each with different push energy configurations. The rate of successful SWS estimation was linearly proportional to the push energy. SWEI measurements with higher push energy were successful in patients for whom standard push energy levels failed. The findings also suggest that liver capsule depth could be used prospectively to identify patients who would benefit from elevated output. We conclude that there is clinical benefit to using elevated acoustic output for hepatic SWSmeasurement in patients with deeper livers. (E-mail: yufeng.deng@duke.edu) Published by Elsevier Inc. on behalf of World Federation for Ultrasound in Medicine & Biology.
A Review of payments for environmental services (PES) experiences in Cambodia

This paper presents a broad overview of payments for environmental services (PES) experiences in Cambodia. First, we explore the legal and policy environment for PES, including its promotion by international donors and nongovernmental organizations (NGOs), and its uptake by government actors. This reveals a long-standing uncertainty over whether the government is willing to support PES, and a lack of clarity about what PES actually represents in practice. Second, taking a broad definition of PES, we examine the full range of payments-based schemes for conservation currently operating in Cambodia. These include community-based conservation agreements, direct payments for biodiversity conservation, PES schemes in the context of hydropower, and REDD+ schemes in the context of climate change mitigation. Overall, these payment schemes demonstrate mixed environmental and social effects; and they face a range of technical and practical challenges, relating to the governance context of Cambodia and difficulties in securing any ‘willingness to pay' for environmental services beyond donor-funded schemes. More profoundly, these findings illustrate that ‘environmental services markets' do not naturally come into being; but instead require a lot of political and discursive work, institution-building, and donor funding to become established. For this reason, we see PES succeeding only in isolated cases, with dedicated NGO-backing and the presence of niche markets. Beyond that, we observe significant challenges for PES and REDD+ in Cambodia, relating mainly to the apparent ‘state capture' of these mechanisms. Such an outcome risks the erosion of conservation and local livelihood objectives that international donors and buyers of environmental services are seeking. It also presents the ethical problem of PES and REDD+ being absorbed into the Cambodian regime simply as adjuncts to the status quo.