Miracle-dz/UniFAR-FTUs huggingface dataset:
Study on Synchronization of Space Docking Mechanism's Docking Lock

Synchronization index of docking lock's motion is the important technical parameter that explains whether the docking mechanism can connect and separate normally.It's very difficult that how to model the flexible tightwire through the MSC.ADAMS software.This paper makes use of the subroutine that expressed by mathematical relation to simulate the role of the tightwire,through which the synchronization of the docking lock is researched.Finally,by comparing the result of the simulation with the test data,the reasonable suggestions are presented.
Fault feature extraction of rolling element bearings based on short-time processing

Fault diagnosis of bearings is a crucial part of the maintenance process of the rotary machinery. Extracting the cyclic characteristics of the impact force is of significant importance for the bearing diagnosis. To highlight the fault features from signals combined with heavy background noise, a novel approach for bearing fault diagnosis based on the short-time processing is proposed. Fault signals are regarded as periodic impulse response signals. Firstly, a vibration signal is band-pass filtered with a subsequent spectral analysis. Then we integrate the energy of the filtered signal with a constant length, and the natural logarithm is considered to obtain the energy curve. The energy curve is a straight decaying curve, and its spectral energy is more concentrated on the fault characteristic frequency compared with envelope. Finally, the fault characteristic frequency of the bearing is found by the spectral analysis of the energy curve. The effectiveness of the proposed method is verified by simulation and experiments. The harmonics and sidebands in logarithmic energy spectrum are suppressed well, and the fault characteristic frequency is highlighted. Comparison of the proposed method with Hilbert envelope method shows that the proposed method can highlight the fault characteristic frequency.
Adaptive Immune Responses, Immune Escape and Immune-Mediated Pathogenesis during HDV Infection

The hepatitis delta virus (HDV) is the smallest known human virus, yet it causes great harm to patients co-infected with hepatitis B virus (HBV). As a satellite virus of HBV, HDV requires the surface antigen of HBV (HBsAg) for sufficient viral packaging and spread. The special circumstance of co-infection, albeit only one partner depends on the other, raises many virological, immunological, and pathophysiological questions. In the last years, breakthroughs were made in understanding the adaptive immune response, in particular, virus-specific CD4+ and CD8+ T cells, in self-limited versus persistent HBV/HDV co-infection. Indeed, the mechanisms of CD8+ T cell failure in persistent HBV/HDV co-infection include viral escape and T cell exhaustion, and mimic those in other persistent human viral infections, such as hepatitis C virus (HCV), human immunodeficiency virus (HIV), and HBV mono-infection. However, compared to these larger viruses, the small HDV has perfectly adapted to evade recognition by CD8+ T cells restricted by common human leukocyte antigen (HLA) class I alleles. Furthermore, accelerated progression towards liver cirrhosis in persistent HBV/HDV co-infection was attributed to an increased immune-mediated pathology, either caused by innate pathways initiated by the interferon (IFN) system or triggered by misguided and dysfunctional T cells. These new insights into HDV-specific adaptive immunity will be discussed in this review and put into context with known well-described aspects in HBV, HCV, and HIV infections.
Techno-Socio-Economic Impact of Joint Energy Resource Allocation Scheme in FiWi Network

In this paper, we consider a fiber-wireless (FiWi) network consisting of 10-Gigabit-capable passive optical network (XG-PON) and wireless fidelity (WiFi). In order to mitigate the conventional limitations of grid-power supply, an off-grid FiWi network is considered, where the components of the network such as optical network units (ONUs) and IEEE 802.11 access points (APs) are powered using renewable sources of energy such as photovoltaic (PV) panels and wind turbines along with batteries. Depending on the availability of renewable power at different locations, the energy resources available to power ONU-AP may vary. Consequently, we propose a joint energy resource allocation framework to minimize the number of PV panels and batteries required by ONU-AP based on its location as well as throughput requirement of the users. An analytical framework is derived to justify the accuracy of the proposed joint energy resource allocation framework. Further, a socio-economic analysis and trade-off analysis between allocation efficiency and cost is also presented. The results show a good agreement between the analytical and the proposed approach. It has also been observed that location with high renewable energy sources contributes to a significant reduction in the number of PV panels and batteries requirement and, therefore, has lower cost and carbon dioxide (CO2) emissions.
Development of Permanently Installed Magnetic Eddy Current Sensor for Corrosion Monitoring of Ferromagnetic Pipelines

Permanently installed sensors are a cost-effective solution for corrosion monitoring due to their advantages, such as less human interference and continuous data acquisition. Some of the most widely used permanently installed corrosion sensors are ultrasonic thickness (UT) gauges. However, UT sensors are limited by the need for coupling agents between pipe surfaces and sensors. The magnetic eddy current (MEC) method, on the other hand, does not require couplant and can be used over insulations. With the development of powerful rare earth magnets, MEC sensors with low power consumption are possible, and there is the prospect of using them as permanently installed sensors. A novel wireless magnetic eddy current sensor has been designed and optimized using finite element simulation. Sensitivity studies of the sensors reveal that the excitation frequency is a critical parameter for the detection of corrosion defects. An in-depth explanation of the relationship between the sensitivity of the sensor and the excitation frequency is presented in this paper. The results of an accelerated corrosion test, conducted to simulate the service environment of the sensor, are also discussed. It was observed that the sensor signals are very sensitive to corrosion defects and show no subtle differences due to temperature and humidity changes.
Dietary supplementation of thiamine enhances colonic integrity and modulates mucosal inflammation injury in goats challenged by lipopolysaccharide and low pH

Abstract The current study aimed to investigate the protective effects of dietary thiamine supplementation on the regulation of colonic integrity and mucosal inflammation in goats fed a high-concentrate (HC) diet. Twenty-four Boer goats (live weight of 35·62 (sem 2·4) kg) were allocated to three groups (CON: concentrate/forage = 30:70; HC; concentrate/forage = 70:30 and HCT: concentrate/forage = 70:30 with 200 mg thiamine/kg DMI) for 12 weeks. Results showed that compared with the HC treatment, the HCT group had a significantly higher ruminal pH value from 0 to 12 h after the feeding. The haematoxylin–eosin staining showed that desquamation and severe cellular damage were observed in the colon epithelium of the HC group, whereas the HCT group exhibited more structural integrity of the epithelial cell morphology. Compared with the HC treatment, the HCT group showed a markedly increase in pyruvate dehydrogenase and α-ketoglutarate dehydrogenase enzymes activity. The mRNA expressions in the colonic epithelium of SLC19A2, SLC19A3, SLC25A19, Bcl-2, occludin, claudin-1, claudin-4 and ZO-1 in the HCT group were significantly increased in comparison with the HC diet treatment. Compared with the HC treatment, the HCT diet significantly increased the protein expression of claudin-1 and significantly decreased the protein expression of NF-κB-related proteins p65. The results show that dietary thiamine supplementation could improve the colon epithelial barrier function and alleviate mucosal inflammation injury in goats after lipopolysaccharide and low pH challenge.
Effect of 3D-Printed PLA Structure on Sound Reflection Properties

3D printing technique is currently one of the promising emerging technologies. It is used in many areas of human activity, including acoustic applications. This paper focuses on studying the sound reflection behavior of four different types of 3D-printed open-porous polylactic acid (PLA) material structures, namely cartesian, octagonal, rhomboid and starlit structures. Sound reflection properties were evaluated by means of the normal incidence sound reflection coefficient based on the transfer function method using an acoustic impedance tube. In this study, various factors affecting the sound reflection performance of the investigated PLA samples were evaluated. It can be concluded that the sound reflection behavior of the tested PLA specimens was strongly affected by different factors. It was influenced, not only by the type of 3D-printed open-porous material structure, but also by the excitation frequency, the total volume porosity, the specimen thickness, and the air gap size behind the tested specimen inside the acoustic impedance tube.
Short-Term Adaptations in Skeletal Muscle Mitochondrial Oxidative Capacity and Metabolic Pathways to Breaking up Sedentary Behaviors in Overweight or Obese Adults

Breaking up sedentary behavior with short-frequent bouts of physical activity (PA) differentially influences metabolic health compared with the performance of a single-continuous bout of PA matched for total active time. However, the underlying mechanisms are unknown. We compared skeletal muscle mitochondrial respiration (high-resolution respirometry) and molecular adaptations (RNA sequencing) following 4-day exposure to breaks vs. energy-matched single-continuous PA bout in inactive adults with overweight/obesity. Participants (9M/10F, 32.2 ± 6.4 years, 30.3 ± 3.0 kg/m2) completed three 4-day interventions of a randomized cross-over study: SED, sedentary control; MICRO, 5 min brisk walking each hour for 9 h; ONE: 45 min/d continuous brisk walking bout. Fasted muscle biopsies were collected on day 5. Mitochondrial coupling in the presence of lipid-associated substrates was higher after ONE (4.8 ± 2.5) compared to MICRO (3.1 ± 1.1, p = 0.02) and SED (2.3 ± 1.0, p = 0.001). Respiratory rates did not differ across groups with carbohydrate-associated substrates. In pathways associated with muscle contraction transcription signaling, ONE and MICRO similarly enhanced Oxidative Phosphorylation and Sirtuin Signaling expression (p < 0.0001, for both). However, ONE (p < 0.001, for all), but not MICRO, had greater pathway enrichment, including Ca++, mTOR, AMPK, and HIF1α signaling, than SED. Although breaking up sedentary behavior triggered skeletal muscle molecular adaptations favoring oxidative capacity, it did not improve mitochondrial function over the short term.
Assessing the poverty impact of the COVID-19-induced tourism crisis in Tanzania: a social accounting matrix microsimulation analysis

Abstract The COVID-19 pandemic has caused major disruptions to international tourism and has stimulated research interest. This study examines links between COVID-19-induced tourism disruption and poverty in Tanzania. Unlike previous studies linking COVID-19, tourism and poverty, this paper uses a social accounting matrix (SAM) microsimulation analysis that allows decomposition of poverty indices by population subgroup and assessment of the drivers of aggregate poverty. The results of the SAM multiplier analysis indicate that all households will experience reduced incomes, and that this effect will be more pronounced in urban than rural households. The microsimulation results suggest that the COVID-19-induced tourism crisis will exacerbate the poverty headcount, poverty gap and poverty severity, with urban and rural non-farm households being most affected. The results of the poverty decomposition show that the growth effect has a stronger impact than the inequality effect on increased poverty. Poverty increases and inequality decreases simultaneously. The paper suggests several demand- and supply-side policies that may help to build tourism resilience and recovery and alleviate poverty in Tanzania in the post-COVID world.
Acceptance of COVID-19 and Influenza Vaccine Co-Administration: Insights from a Representative Italian Survey

Co-administration of coronavirus disease 2019 (COVID-19) and seasonal influenza vaccines has several advantages, has been advocated by various public health authorities and should be seen as an opportunity to increase the uptake of both vaccines. The objective of this survey was to quantify the acceptance of concomitant COVID-19/influenza vaccination and to identify its correlates in a representative sample of Italian adults. Of 2463 participants, a total of 22.9% were favorable to vaccine co-administration, while 16.6% declared their firm unwillingness to receive both vaccines simultaneously. The remaining 60.5% of subjects could be dubbed hesitant to some degree. Compliance with the primary COVID-19 vaccination schedule (adjusted proportional odds ratio (aOR) = 7.78), previous influenza vaccination (aOR = 1.89) and trust in public health institutions (aOR = 1.22) were the main determinants of positive attitudes toward vaccine co-administration. Other significant correlates included age, sex, perceived disease severity and vaccination risk–benefit, being offered a more personalized influenza vaccine and recent seeking for influenza-related information. In Italy, hesitancy toward COVID-19/influenza vaccine co-administration is common and appears to be higher than hesitancy toward either vaccine administered alone. This pattern is multifaceted and requires specific and tailored strategies, with public health institutions playing the central role.
Development of Communication System of the Loop Simulation Test Platform for CAN-bus-based AMT

Electronic control unit(TCU)is the core of AMT control system. The traditional development needs a lot of debugging on actual vehicle,which makes for waste of time and money. The loop simulation experimental system for AMT can significantly improve the efficiency of development. In order to meet the requirements of the real-time performance,flexibility and reliability,it designs a control system based on CAN-bus,the overall structure of the control system and the hardware circuit of the communication module. Based on SAE J1939,it realizes the information sharing among each node.
Photo Effect Studies in Graphene/N-GaAs Schottky Junction Using NEGF Method for Photovoltaic Application

In this paper, we present the photovoltaic characteristics of nanoscale Schottky junction solar cell consisting of graphene and GaAs using numerical simulation based on non-equilibrium Green’s function formalism. In our model, light-matter interaction is formulated by the coupling and scattering self-energy matrices whereas heterostructure is designed with a Hamiltonian matrix. An efficiency of 2.36% is obtained for monolayer graphene on GaAs; the efficiency is later enhanced to 5.40% by increasing both the number of graphene layers and the doping concentration of GaAs. The parameters to calculate power conversion efficiency, series and shunt resistances are extracted from the J-V characteristic. The I-V characteristic is also numerically simulated to extract reverse saturation current, ideality factor, and rectification ratio. Moreover, the power density is calculated for the optimized structure; the maximum power density of 7.46 mW/cm2 is obtained for four layers of graphene and a doping concentration of 1017/cm3 in GaAs.
COVID-19 pandemic effects on health worker’s mental health: Systematic review and meta-analysis

Abstract Background Healthcare workers (HCWs) exposed to coronavirus 19 (COVID-19) are at high risk of developing mental health concerns across several domains. The aim of this study is to determine the updated, global frequency of these outcomes. Methods A multistep literature search was performed from database inception until March 1, 2021. PRISMA/MOOSE-compliant systematic review and PROSPERO protocol were used to identify studies reporting on depression, anxiety, acute stress, post-traumatic symptoms, insomnia, and burnout in HCWs exposed to COVID-19. A quantitative meta-analysis with random effects was conducted to analyze the proportion rate of the mental health disorders. Sensitivity analyses were performed to investigate the effect of the different continents and scales. Meta-regression analyses were conducted to examine the effect of gender, age, and work position. Results 239 articles were included (n = 271,319 HCWs, mean age = 36.08 ± 8.33 (66.99% female). 33% HCWs exposed to COVID-19 reported depressive symptoms (95% confidence intervals [CI] = 28–38%), 42% anxiety features (95% CI = 35–48), 40% acute stress (95% CI = 32–47), 32% post-traumatic symptoms (95% CI = 26–37%), 42% insomnia (95% CI = 36–48), 37% burnout (95% CI = 31–42). Sensitivity analyses did not show statistically significant differences. Meta-regressions found a statistically significant lower prevalence of post-traumatic symptoms in Asia. Conclusions HCWs exposed to COVID-19 were found to have a significant prevalence of mental health concerns in all domains analyzed. The effects of COVID-19 on HCWs’ mental health could be underestimated and the future consequences dismissed.
Enzyme-Mediated Quenching of the Pseudomonas Quinolone Signal (PQS): A Comparison between Naturally Occurring and Engineered PQS-Cleaving Dioxygenases

The opportunistic pathogen Pseudomonas aeruginosa employs quorum sensing to govern the production of many virulence factors. Interference with quorum sensing signaling has therefore been put forward as an attractive approach to disarm this pathogen. Here, we analyzed the quorum quenching properties of natural and engineered (2-alkyl-)3-hydroxy-4(1H)-quinolone 2,4-dioxygenases (HQDs) that inactivate the P. aeruginosa signal molecule PQS (Pseudomonas quinolone signal; 2-heptyl-3-hydroxy-4(1H)-quinolone). When added exogenously to P. aeruginosa cultures, all HQDs tested significantly reduced the levels of PQS and other alkylquinolone-type secondary metabolites deriving from the biosynthetic pathway, such as the respiratory inhibitor 2-heptyl-4-hydroxyquinoline N-oxide. HQDs from Nocardia farcinica and Streptomyces bingchenggensis, which combine low KM values for PQS with thermal stability and resilience in the presence of P. aeruginosa exoproducts, respectively, attenuated production of the virulence factors pyocyanin and pyoverdine. A delay in mortality was observed when Galleria mellonella larvae were infected with P. aeruginosa suspensions treated with the S. bingchenggensis HQD or with inhibitors of alkylquinolone biosynthesis. Our data indicate that quenching of PQS signaling has potential as an anti-virulence strategy; however, an efficient anti-virulence therapy against P. aeruginosa likely requires a combination of agents addressing multiple targets.
Social, Clinical and Psychometric Factors Affecting Self-Rated Oral Health, Self-Rated Health and Wellbeing in Adults: A Cross-Sectional Survey

Background: Many studies examined and reported oral and general health inequalities in clinical health, SROH and SRH. Objectives: The study aims to explore the social influences, gradients and predictors of self-rated oral health (SROH) and self-rated health (SRH) and wellbeing in Greek adults. Methods: Cross-sectional study, of men and women, aged 65 years and over (N = 743) in Greece. Descriptive and statistical analyses were performed for dentate and edentulous participants. For the association between socioeconomic exposures and binary outcomes, logistic regression was performed to estimate Odds Ratios and 95% Confidence Intervals (OR, 95% CI); levels of association and Cramer’s V were applied to calculate associations and p-values. Results: The objective socioeconomic measures, such as household income, education level and last main occupation were significant predictors and determinants of both SROH and self-rated health (SRH). For Satisfaction with life (SWL), there was a diversity in the results analogous to the dental status of the participants. Household income and SSS were predictors of SWL in dentate participants. In the total sample Household income, occupation and SSS, were predictors of SWL, while in edentulous participants only occupation and SSS were statistically significant (p < 0.05). Subjective social status was statistically significant for SROH, SRH and SWL (p < 0.01). More association with SROH and SRH in dentate participants (p < 0.05). Conclu-sion: There are socioeconomic gradient inequalities in SROH and SRH in Greek adults living in Attica area. Subjective social status is a predictor of SROH, SRH and SWL. The need to prioritize interventions to eliminate disparities and inequalities in oral and general health and wellbeing of elders is evident.
Sub-millimeter precision 3D measurement through a standard endoscope with time of flight

Endoscopic surgery has been widely adopted across specialties because it reduces patient trauma, risk, and recovery time as compared to open procedures. The foremost challenge of endoscopic surgery is the inability to see in three dimensions, a disadvantage that significantly increases procedure time and uncertainty by inhibiting depth perception as well as localization and measurement capability. State-of-the-art approaches in endoscopic 3D measurement are largely based on a combination of structured light and stereo vision, but are limited in their robustness and applicability to clinical workflow. Both approaches require a large baseline and are not supported by most handheld off-the-shelf endoscopes; stereo methods specifically are sensitive to scenes lacking features or containing disturbances such as smoke and specular reflections, which are common in surgery. To address these issues, we propose an alternative method for 3D measurement based on time-of-flight (TOF), a depth sensing modality which is inherently monocular and known to be insensitive to featureless scenes and many types of disturbances. Specifically, we develop a TOF imaging module adapter compatible with off-theshelf endoscopes and demonstrate single-shot, sub-millimeter 3D measurement accuracy on animal tissue. These results are significant because they suggest widespread compatibility with existing operating room equipment and workflow and applicability to a wide variety of clinically relevant surgical tasks including measurement of tumors, hernias, and anastomoses, intra-operative registration of the surgical scene to high-quality static 3D imaging data, and control of surgical robots.