Miracle-dz/UniFAR-FTUs huggingface dataset:
CODEN: IJPNL6 SIMULTANEOUS DETERMINATION OF ESOMEPRAZOLE MAGENISUM TRIHYDRATE AND NAPROXEN BY COMBINED HPLC-CHEMOMETRIC TECHNIQUES AND RP- HPLC METHOD

New chemometric approaches were applied to high performance liquid chromatography (HPLC) for simultaneous determination of esomeprazole magenisum trihydrate and naproxen in their synthetic mixture. These chemometric approaches were applied to the multiwavelength HPLC peak area ratio obtained by plotting the chromatograms at the five wavelengths using diclofenac sodium as internal standard (IS). The multichromatograms were obtained by using the diode array detector (DAD). A mixture of 20 mM acetate buffer (pH=4.2) and acetonitrile (35:65, v/v) was used as a mobile phase on a 5μm (4.6 x 250mm) Inertsil ® C18 Column at a flow rate of 1.5 mL/min to separate and determine the investigated drugs in their synthetic mixture. For comparison purposes, a new validated developed classic HPLC method at 299 nm was used to confirm the results obtained from HPLC-chemometric calibration techniques. There was no significant difference between the methods compared.
Characterization of 6T CMOS SRAM in 65nm and 120nm Technology using Low power Techniques

As the channel length of MOSFETs is scaling down, the Power dissipation of the SRAM cells become the major concern for future technology. In this paper, stable SRAM cell’s power dissipation reduction in 6T static random access memory (SRAM), is described by using dynamic selfcontrollable voltage level (SVL) switch. Total power dissipation is reduced by 74/% and 84% at 1.2 volt and die area is increased by 36% and 69% from 120nm to 65nm technology respectively. The schematic and layout are drawn on 120nm and 65nm technology file on a Dsch tool and their analysis is done on a Microwind 3.1 tool and BSIM simulator.
Mechanical Properties of Micro and Nano TiO 2 / Epoxy Composites

Epoxy with different volume fractions (1, 2, 3, 4, 5, 7, 10, 15 and 20 vol% ) of microparticles TiO2 (50-μm) and nanoparticles TiO2 (50-nm) were used to prepare epoxymicrocomposites and epoxynanocomposites. Ultrasonic mixing process was employed to disperse the nano-particles and microparticles into the resin system. The mechanical performance of the nanocomposites and microcomposites were then characterized by flexural testing, Differential Scanning Calorimeter (DSC) which was used to evaluate glass transition temperature for epoxy, epoxynanocomposites and epoxy-microcomposites. The microstructure of fracture surfaces was examined by Scanning Electron Microscope (SEM) techniques in order to identify the relevant fracture mechanisms involved. The Flexural strength, Young modulus and fracture toughness of nanocomposites were increased at low volume fraction (less than 7 vol%). At higher volume fraction both flexural strength and fracture toughness decrease while Young modulus still higher than that of epoxy. The flexural strength and fracture toughness of epoxy-microcomposites decreases with increasing the volume fraction of TiO2 microparticles specially at high volume fraction while Young modulus increases with increasing the volume fraction. Glass transition temperature of EP/TiO2 nanocomposites was increased at specific volume fraction while glass transition temperature decreased for other TiO2 nanoparticles mixing ratio and for TiO2 microparticles additions. SEM images show the morphology of fractured structure of EP/TiO2 nanocomposites with minimum defects at low volume fractions of TiO2 nanoparticles, while the morphologies of fractured surface show brittle fracture with dispersed stresses in more than one crack propagation direction and less flat area with existence of TiO2 nanoparticles. Also roughness of fractured structure was at minimum value at 4% vol. fraction of TiO2 nanoparticles. Keywords— Epoxy, Mechanical Properties, Nanocomposites, TiO2 nanoparticles.
Biological Activity of an Essential Oil Blend in Human Dermal Fibroblasts

Essential oils are complex mixtures of aromatic compounds naturally produced in plants. They have been used historically as well as currently for treating a variety of diseases and maintaining health in humans (Lv et al., 2013; Perry & Perry, 2006). Recent pre-clinical and clinical studies have provided evidence supporting the benefits of essential oils to human health (Kozioł et al., 2014; Navarra et al., 2015), resulting in a wider acceptance and use of essential oils in the US and worldwide. Despite this trend, very few studies have elucidated the mechanisms of action of essential oils inhuman cells.
A Survey on Privacy Preservation in Cloud Computing

— By integrating multiple private and public cloud services, hybrid clouds can effectively provide dynamic scalability of service and data migration. Security plays a vital during the transmission of data from the sender to the receiver in any environment. The challenge in privacy preserving Back-Propagation Neural Network Learning is avoiding the attack of personal data privacy. Due to the enlargement of distributed computing environment. In such distributed scenarios, privacy concerns often become a big concern. Secure computation provides a solution to this problem. With the invention of new technologies, Computing, it has been more convenient than ever for users across the Internet, who may not even know each other, whether it is data mining, in databases or in any networks, resolving privacy problems has become very important.
Secure Neighbor Discovery in Wireless Networks by Detecting Various Attacks

Neighbor discovery is an essential part of many protocols for wireless networks which includes routing, leader election within a cluster and group management. If the detection of neighbor fails, communication and performance of the protocol decreases. Wireless networks as the name indicates uses the Radio Frequency (RF) as communication medium and are extensively being used in various military and commercial applications. Wireless networks, due to their nature of deployment are vulnerable to various attacks. Wormhole or Relay attack, Selective dropper attack, Cloning attack, Denial of Service (DoS) attack and Modifier attack etc. In this paper we present the Mobile agent based method which offers a measure of security against various attacks by allowing participating nodes to determine whether they are the neighbors.
COMPARISON OF DIFFERENT PARAMETERS USED IN GMM BASED AUTOMATIC SPEAKER RECOGNITION

—The performance of Speaker recognition systems has improved due to recent advances in speech processing techniques but there is still need of improvement. In this paper we present the comparison of different parameters used in automatic speech recognition system to increase the accuracy of the system. The main goal here is a detailed evaluation of the parameters used in Automatic speech recognition system such as window type, MFCC frame size, number of Gaussian mixtures and GMM & VQ/GMM technique . In this paper we propose a decision function by using vector quantization techniques to decrease the training model for GMM in order to reduce the processing time.
Genomic diversity in Madhya Pradesh, India: Genetic relationship among three ethnic populations from Madhya Pradesh based on STR polymorphism

Available online on http://www.ijlsci. in ISSN: 2320-964X (Online) ISSN: 2320-7817 (Print) Genomic diversity based on 4 STR loci, CSF1P0, TPOX , TH01 and FGA is studied in Gond, Bhil and Brahmin populations of the Madhya Pradesh, India. The 161 blood samples analysed for the present study. For this study samples was collected from Betul (Gond), Bhil and Brahmin (Neemach and Mandsaur). The population wise average Ho/He ratio at four STR loci amongst the three studied population was calculated as 0.979 for Gond, 1.016 for Bhil and 1.029 for Brahmin population of Madhya Pradesh. All loci fall under Hardy-Weinberg equilibrium except TPOX. These STR loci were highly informative and discriminating with Power of discrimination values of all tested loci was above 80%. Highest PD values were obtained by FGA locus in all studied populations about 95%.
Advanced Image Watermarking Using SVD Technique

— Digital image watermarking is the enabling technology to prove ownership of copyrighted material, to solve the problem of piracy and to detect the originator of illegally made copies. Digital watermarking is a technique which allows an individual to add hidden copyright notices or other verification messages to digital audio, video, or image signals and documents. The information which is embedded is called watermark which can be visible or invisible depending upon whether the watermark appears visible or invisible to the casual viewer. The objective of the presented research work is to present a more secure dual level, simple, highly imperceptible, and robust watermarking technique. In this research work, a dual Level semi blind image watermarking scheme in transformed domain is proposed. Singular Value Decomposition (SVD) is used to transform the image. The two watermarks are embedded into green component and blue component of the image. To generate the edge image canny edge detector is used. The proposed algorithm is implemented and experiments are conducted to check the performance of the algorithm using MATLAB 7.10. 0 version. The performance of the presented image watermarking algorithm is evaluated on the basis of Imperceptibility, security, complexity, embedding time, and robustness and experiments are conducted on many colored images of various sizes .
A Study in Neonatal Sepsis Using Polymerase Chain Reaction-Based DNA Sequencing to Detect the Aetiological Agent in the Peripheral Blood of the Neonates with Sepsis

Blood culture, the gold standard for diagnosis of neonatal sepsis has low sensitivity and is time consuming. Therefore, objective is development and application of Polymerase chain reaction (PCR)-based DNA sequencing to detect and identify bacterium causing neonatal sepsis in culture negative specimens. Sixty three peripheral blood and 8 cerebrospinal fluid (CSF) referred from tertiary level Neonatal care Unit of the multi-specialty hospital from January 2012 to August 2013 were included. Specific Gram positive and Gram negative PCR followed by 16SrRNA region DNA sequencing was carried out. Based on DNA homology with Genbank sequences bacterial species were identified. Clinical details of these neonates including risk factors for early and late onset sepsis, reports of septic screen, blood culture and short term outcome till discharge were collected by retrospective chart review. PCR based DNA sequencing revealed 56 bacterial genomes comprising of 55 single bacterial species and 1 mixed bacterial species. Among them, 47 (84%) were Gram negative, 5 (8.9%) were Gram positive and 4 (7.1%) were uncultured bacterium. Escherichia coli (n =16; 27.5%) was the predominant bacterium identified. This study revealed newer emerging bacterial pathogensEscherichia fergusonii, Cronobacter dublinensis, Enterobacter hormachei, Janibacter species, Kluyvera georgiana, Streptococcus pseudopneumoniae as etiological agents of neonatal sepsis. To conclude, PCR based DNA sequencing is a rapid and specific molecular biological test to identify the causative agent of neonatal sepsis. Our study revealed novel bacterial pathogens as aetiological agents of neonatal sepsis. K e y w o r d s
Bioaccumulation of heavy metals in the organs and tissues of Xenopus laevis and sediment concentrations from Alaro Stream in Ibadan

A study was carried out on the bioaccumulation of heavy metals (Lead, Cadmuim, Arsenic and Nickel) in the organs of Xenopus laevis and concentration in the sediments of Alaro Stream, Ibadan. Edible frogs are an affordable source of protein that is abundant and widely consumed even though studies on heavy metal bioaccumulation in their organs is relatively scarce in Nigeria. Twenty three (23) frogs were collected from disused crab holes, water surface and along the shore of the stream. Collected frogs were washed and dissected to remove the bones, gut, heart, liver and muscle for oven drying at 120C for 8 hours. Dried organ samples were pulverized and acid digested for heavy metal analyses. All the mean As and Ni concentration in the organs of Xenopus laevis was higher than the World Health Organization’s (WHO) permissible limit guideline standard of 0.01ppm and 0.07ppm respectively. With of the exception of the gut (1.56ppm), all the mean Pb in the organs were below the WHO’s permissible limit guideline standard of 1ppm. With the exception of the gut (0.069ppm) and the bones (0.063ppm), all the other organs had mean Cd level below the WHO’s permissible limit of 0.05ppm. All detectable heavy metals (Ni and Pb) in the sediment were above regulatory standards. The study shows that most of the heavy metals bioaccumulated in the organs of Xenopus laevis higher than the recommended World Health Organization’s permissible limit thereby making the edible frogs caught in Alaro Stream unfit for human consumption. [Emmanuel Teryila Tyokumbur. Bioaccumulation of heavy metals in the organs and tissues of Xenopus laevis and sediment concentrations from Alaro Stream in Ibadan. N Y Sci J 2016;9(3):38-42]. ISSN 1554-0200 (print); ISSN 2375-723X (online). http://www.sciencepub. net/newyork. 7. doi:10.7537/marsnys09031607.
Image Denoising Techniques Using Dual Tree Complex and Hyperanalytic Wavelet Transform With Bi-Shrink Filter

: This paper focuses on the comparison of the image denoising techniques using two different complex wavelet transforms namely Dual Tree Complex Wavelet Transform (DTCWT) and Hyperanalytic Wavelet Transform (HWT). The limitations of Discrete Wavelet Transform (DWT) such as, poor shift sensitivity and poor directionality are overcome by using the complex wavelet transforms, thus, complex wavelet transforms are preferred to DWTs in the signal or image processing techniques. This paper presents the quantitative comparison of the performances of DTCWT and HWT based image denoising techniques, by using the bivariate shrinkage technique for filtering the noisy wavelet coefficients.
A Rectangular Ring Shaped Ultra-Wide Band Pass Filter Design

A rectangular ring type band pass filter with U-shaped geometries kept in ring is proposed in this paper. Feed are connected at the end of open ended stubs. Presented filter is suitable for the application of wlan or the application using frequencies in L-band range. A flat passband response can be achieved when it is employed to implement a bandpass filter. The resonator also exhibits attenuation poles close to the edges of the passband, thereby offering sharp rejection in the bandpass filter response. Moreover, since the signal applied at the input port is effectively forced to travel mainly through the transmission line path over the passband frequency, the loss incurred by the coupled lines is minimized. Extensive theoretical analysis of the rectangular ring and design example of the bandpass filter prototypes based on the ring structure is given. The proposed geometry is simulated through ie3d software, and results are purely based on the simulation results.
Software Fault Detection using the Data Pre-Processing and Support Vectore Machine

- With increases use of high speed internet huge organization like banking, hospital and industrial work are done using the software rather than manual work. So this organization are required high quality software. If failure happen in the system is effect the financial cost of the organization. Software fault detection model is used for to identify the fault in software which cause the failure. In this paper fault detection model is proposed which used data pre-processing and support vector machine classifier.in data pre-processing feature ranking is perform using information gain and feature cluster is form using fuzzy c-means clustering.
Detection of Diabetic Wounds Based on Segmentation Using Accelerated Mean Shift Algorithm

Diabetic foot ulcers represent a significant health issue. Currently, clinicians and nurses mainly base their wound assessment on visual examination of wound size and healing status, while the patients themselves seldom have an opportunity to play an active role. Hence, a more quantitative and cost-effective examination method that enables the patients and their caregivers to take a more active role in daily wound care potentially can accelerate wound healing, save travel cost and reduce healthcare expenses. This proposed novel has a wound image which is captured by the camera. After that, the system performs wound segmentation by applying the accelerated mean shift algorithm. Specifically, the outline of the foot is determined based on the wound boundary is found using a simple connected region detection method. Within the wound boundary, the healing status is next assessed based on red–yellow–black color evaluation model. Moreover, the healing status is quantitatively assessed, based on trend analysis of time records for a given patient. Experimental results on wound images collected in UMASS—Memorial Health Center Wound Clinic (Worcester, MA) following an Institutional Review Board approved protocol show that our system can be efficiently used to analyze the wound healing status with promising accuracy. Keywords— Mean shift algorithm, Wound segmentation, Healing status, Maximum Likelihood principle, Risk analysis.
The effects of instrument-assisted soft tissue mobilization compared to other interventions on pain and function: a systematic review

Background: Instrument-assisted soft tissue mobilization (IASTM) is an emerging intervention in physical therapy. With the increasing prevalence of pain and disability associated with musculoskeletal impairments, it is essential to identify the most effective treatment strategies. Objective: To systematically examine evidence on the effectiveness of IASTM, compared to other interventions on patients with pain and disability resulting from musculoskeletal impairments. Methods: Numerous databases were searched using the terms Instrument Assisted Soft Tissue, Pain, Function, Graston, and soft tissue mobilization (STM). Inclusion criteria included: randomized clinical trials on patients with musculoskeletal impairments, STM had to be a treatment intervention, performed on human subjects, and had to capture a measure of pain or function. Articles were excluded if they were not published in English or if the subjects were of the pediatric or geriatric populations. Included articles were appraised using the Physiotherapy Evidence Database (PEDro) scale. Results: Seven studies met the inclusion criteria. All seven articles scored a minimum 4/10 on the PEDro scale. The studies involved treatment of numerous anatomical locations and the majority of the studies demonstrated significant improvements in pain and/or range of motion when compared to control or other conservative treatment groups. Conclusions: These outcomes support the idea that IASTM may have an impact on physiological changes by providing an increase in blood flow, reduction in tissue viscosity, myofascial release, interruption of pain receptors, and improvement of flexibility of underlying tissue. It is suggested that IASTM is an effective treatment intervention for reducing pain and improving function in less than a three-month period.
Bioequivalence & Bioavailability

A rapid, sensitive and specific method for quantifying hydroxocobalamin in human plasma using paracetamol as the internal standard (IS) is described. The analyte and the IS were extracted from plasma by liquid-liquid extraction using an organic solvent (ethanol 100%; -20°C). The extracts were analyzed by high performance liquid chromatography coupled with electrospray tandem mass spectrometry (HPLC-MS-MS). Chromatography was performed on Prevail C8 3 μm, analytical column (2.1×100 mm i.d.). The method had a chromatographic run time of 3.4 min and a linear calibration curve over the range 5-400 ng.mL-1 (r>0.9983). The limit of quantification was 5 ng.mL-1. The method was also validated without the use of the internal standard. The precision in the intra-batch validation with IS was 9.6%, 8.9%, 1.0% and 2.8% whereas without IS was 9.2%, 8.2%, 1.8% and 1.5% for 5, 15, 80 and 320 ng/mL, respectively. The accuracy in intra-batch validation with IS was 108.9%, 99.9%, 98.9% and 99.0% whereas without IS was 101.1%, 99.3%, 97.5% and 92.5% for 5, 15, 80 and 320 ng/mL, respectively. The precision in the inter-batch validation with IS was 9.4%, 6.9%, 4.6% and 5.5% whereas without IS was 10.9%, 6.4%, 5.0% and 6.2% for 5, 15, 80 and 320 ng/mL, respectively. The accuracy in inter-batch validation with IS was 101.9%, 104.1%, 103.2% and 99.7% whereas without IS was 94.4%, 101.2%, 101.6% and 96.0% for 5, 15, 80 and 320 ng/ mL, respectively. This HPLC-MS-MS procedure was used to assess the pharmacokinetics of cobalamin following intramuscular injection 5000 μg in healthy volunteers of both sexes (10 males and 10 females). The volunteers had the following clinical characteristics (according to gender and expressed as mean ± SD [range]): males: age: 32.40 ± 8.00 [23.00-46.00], height: 1.73 ± 0.07 m [1.62-1.85], body weight: 72.48 ± 10.22 [60.20-88.00]; females: age: 28.60 ± 9.54 [18.00-44.00], height: 1.60 ± 0.05 [1.54-1.70], body weight: 58.64 ± 6.09 [51.70-66.70]. The following pharmacokinetic parameters were obtained from the hydroxocobalamin plasma concentration vs. time curves: AUClast, T1/2, Tmax, Vd, Cl, Cmax and Clast. The pharmacokinetic parameters were 120 (± 25) ng.mL -1 for Cmax, 2044 (± 641) ng.hr. mL-1 for AUClast, 8 (± 3.2) ng.mL -1 for Clast, 38 (± 15.8) hr for T1/2 and 2.5 (range 1-6) hr for Tmax. Female volunteers presented significant (p=0.0136) lower AUC (1706 ± 704) ng.hr. mL-1) and larger (p=0.0205) clearance (2.91 ± 1.41 L/hr), as compared to male 2383 ± 343 ng.hr. mL-1 and 1.76 ± 0.23 L/hr, respectively. These pharmacokinetic differences could explain the higher prevalence of vitamin B12 deficiency in female patients. The method described validated well without the use of the internal standard and this approach should be investigated in other HPLC-MS-MS methods. Hydroxocobalamin Quantification in Human Plasma by High-Performance Liquid Chromatography Coupled with Electrospray Tandem Mass Spectrometry in a Pharmacokinetic Study
Conceptual for User Satisfaction with the E-government in North of Jordan

This study aimed to identify the concept of e-government which enables the availability of services to Jordanian, to identify the requirements of application of e-government, and the problems faced at the local level and thus to identify user satisfaction with e-government in Jordan A questionnaire was adjusted and structured base on previous study and distributed in the north of Jordan. Data were analyzed through the use of statistical software SPSS) . The current study had conclusions and recommendations. Statistical analysis shows that there is a statistically significant in all hypotheses except in format use of e-government in Jordan and Satisfaction of user in Jordan p= (0.051) and all of hypothesis have appositive correlation and relationship between them.