Miracle-dz/UniFAR-FTUs huggingface dataset:
The Harvard dictionary of music

This classic reference work, the best one-volume music dictionary available, has been brought completely up to date in this new edition. Combining authoritative scholarship and lucid, lively prose, the Fourth Edition of The Harvard Dictionary of Music is the essential guide for musicians, students, and everyone who appreciates music. The Harvard Dictionary of Music has long been admired for its wide range as well as its reliability. This treasure trove includes entries on all the styles and forms in Western music; comprehensive articles on the music of Africa, Asia, Latin America, and the Near East; descriptions of instruments enriched by historical background; and articles that reflect today's beat, including popular music, jazz, and rock. Throughout this Fourth Edition, existing articles have been fine-tuned and new entries added so that the dictionary fully reflects current music scholarship and recent developments in musical culture. Encyclopedia-length articles by notable experts alternate with short entries for quick reference, including definitions and identifications of works and instruments. More than 220 drawings and 250 musical examples enhance the text. This is an invaluable book that no music lover can afford to be without.
Provinciale Toepassingen voor Wegverkeersgegevens: Gebeurtenisdetectie op basis van NDW Verkeersdata

Provincie Zuid-Holland beschikt over wegverkeersgegevens uit verschillende bronnen. Via lussen in de weg worden intensiteiten en puntsnelheden gemeten en door middel van kentekenherkenningscamera’s worden reistijden vastgelegd. Deze verkeersgegevens zijn zowel actueel als in de vorm van historische gegevens beschikbaar. Provincie Zuid-Holland heeft gevraagd waarvoor ze deze verkeersgegevens zoal zou kunnen gebruiken. Daarnaast is Provincie Zuid-Holland in januari 2012 gestart met een eigen kleine verkeerscentrale: de verkeersmanagementdesk. De verkeersmanagementdesk heeft als taak het beheer van de verkeerslichten en het monitoren van het verkeer op de provinciale wegen. Het monitoren van het verkeer gebeurt momenteel met behulp van camerabeelden en verkeersinformatie van derden. Het is echter ondoenlijk om meer dan honderd camerabeelden tegelijkertijd te bekijken om gebeurtenissen zo snel mogelijk op te sporen; vandaar dat de provincie bijzonder gebaat is bij een systeem dat automatisch melding kan maken zodra zich een ongewone gebeurtenis voordoet. De mogelijkheden voor een dergelijk gebeurtenisdetectiesysteem voor provinciale wegen zijn onderzocht. Hiervoor is gebruik gemaakt van wegverkeersgegevens uit de Nationale Databank Wegverkeersgegevens, voor tweehonderd meetpunten op provinciale wegen in Zuid-Holland. Het afstudeerwerk geeft antwoord op de volgende onderzoeksvraag: Welke wegverkeersgegevens zijn beschikbaar binnen provincie Zuid-Holland en welke operationele toepassingen zijn hiermee te realiseren, hoe kunnen irreguliere verkeerstoestanden op provinciale wegen uit deze verkeersgegevens gedetecteerd worden en hoe kan deze detectiemethode worden ingezet als informatievoorziening aan de verkeersmanagementdesk?
Promoter hypomethylation of NY-ESO-1, association with clinicopathological features and PD-L1 expression in non-small cell lung cancer

Cancer-Testis antigens (CTA) are immunogenic molecules with normal tissue expression restricted to testes but with aberrant expression in up to 30% of non-small cell lung cancers (NSCLCs). Regulation of CTA expression is mediated in part through promoter DNA methylation. Recently, immunotherapy has altered treatment paradigms in NSCLC. Given its immunogenicity and ability to be re-expressed through demethylation, NY-ESO-1 promoter methylation, protein expression and its association with programmed death receptor ligand-1 (PD-L1) expression and clinicopathological features were investigated. Lung cancer cell line demethylation resulting from 5-Aza-2′-deoxycytidine treatment was associated with both NY-ESO-1 and PD-L1 re-expression in vitro but not increased chemosensitivity. NY-ESO-1 hypomethylation was observed in 15/94 (16%) of patient samples and associated with positive protein expression (P < 0.0001). In contrast, PD-L1 expression was observed in 50/91 (55%) but strong expression in only 12/91 (13%) cases. There was no association between NY-ESO-1 and PD-L1 expression, despite resultant re-expression of both by 5-Aza-2′-deoxycytidine. Importantly, NY-ESO-1 hypomethylation was found to be an independent marker of poor prognosis in patients not treated with chemotherapy (HR 3.59, P = 0.003) in multivariate analysis. In patients treated with chemotherapy there were no differences in survival associated with NY-ESO-1 hypomethylation. Collectively, these results provided supporting evidence for the potential use of NY-ESO-1 hypomethylation as a prognostic biomarker in stage 3 NSCLCs. In addition, these data highlight the potential to incorporate demethylating agents to enhance immune activation, in tumours currently devoid of immune infiltrates and expression of immune checkpoint genes.
The Research on Data Mining of Slim Life Mode Based on Cycle Behavior

In this study, data mining of slim life mode based on cycle behavior is propsed. The mining of the periodic behavior is divided into four stages. The first two stages is data pre-processing stage: Firstly, parsing stay point sequence from data sequence of the original location history. Here stay point represent the geographic area to a person's stay for some time; Secondly, cluster mining the sequence of stay point, find out the significant places, such as company, supermarket, home location, etc. Thirdly, mining periodic on the significant places. Take a place as a reference point; abstract the original location history data into binary sequence by the location point in or out the place. Then, combination two popular signal processing method fast Fourier and autocorrelation find the periods of every place. Fourthly, mining the periodic behavior of the places with the same periods, in this article, first construct the periodic behavior probabilistic model, then use the method based on the hierarchical clustering to mining the periodic behavior between different places. At last, an example is introduced.
A robust algorithm for segmenting fluorescence images and its application tosingle-molecule counting

Live-cell fluorescence microscopy produces high amounts of data with a high variability in shapes at low signal-to-noise ratio. An efficient design of image analysis pipelines requires a reliable and robust initial segmentation step that needs little parameter fine-tuning. Here, I present a segmentation algorithm called MinSeg for fluorescence image data that relies on minimal assumptions about the image, and uses statistical considerations to distinguish signal from background. More importantly, the algorithm does not make assumptions about feature size or shape, and is thus universally applicable. I also present a pipeline for the quantification of small complexes with single-molecule fluorescence microscopy using this segmentation algorithm as the first step of the workflow. This pipeline was used for the quantification of a small histone H3 variant protein called CENP-A. We found that the CENP-A nucleosomes are dimers.
An Algorithm To Compute The SR Score And Parameters To Tune Its Performance

Keyword query interfaces (KQIs) for list have involved much notice in the last decade due to their suppleness and ease of use in searching and discover the data. Because any unit in a data set that enclose the query keywords is a probable answer, keyword queries naturally have many potential answers. KQIs must make out the information needs in the rear keyword queries and rank the answers so that the needed answers come out at the top of the list. It is central for a KQI to make out such queries and inform the user or make use of another techniques like query reformulation or query suggestions. It possibly will also use practice such as query results diversification.
Effect of previous ascorbic acid treatment on the fatty acid profile of cobia (Rachycentron canadum) fillets during frozen storage

The present research focuses on the nutritional value of the lipid retention associated with frozen cobia ( Rachycentron canadum ). The effect of a previous soaking in an aqueous ascorbic acid (AA) solution on the fatty acid profile of fish fillets during a further frozen storage period (–18 °C) was investigated. Two different AA concentrations were tested (0.25% and 0.50%) and compared to control conditions. As a result of the frozen storage period (up to 6 months), marked decreases were found in the contents of fatty acid groups such as monounsaturated, polyunsaturated and n-3 polyunsaturated, as well as in the n-3/n-6 ratio. However, a preserving effect on such fatty acid parameters could be observed resulting from the previous AA treatment, which was greater when applying the 0.50% AA concentration. Assessment of the polyene index indicated an increased lipid oxidation development during the frozen storage time; this increase was partially inhibited by the previous AA soaking.
Meta-analysis of B-type natriuretic peptide in diagnosis of congestive heart failure in different clinical settings

Correspondence: Osama Elkhateeb Halifax Infirmary, 1796 Summer Street, Halifax, Nova Scotia, Canada B3H 3A7 Tel +1 902 473 3331 Email osama.elkhateeb@cdha.nshealth. ca Background: B-type natriuretic peptide (BNP) is a neurohormone released from the left ventricle in response to ventricular wall stress and pressure overload. BNP testing has been developed, and aids in identification of patients with suspected congestive heart failure (CHF). The objective of this study was to evaluate the role of BNP as a diagnostic marker of CHF, and determine its value in different clinical settings. Methods: A systematic review and meta-analysis of clinical studies regarding BNP and CHF was conducted. A comprehensive search of Medline, the Cochrane Library, and the reference sections of the primary studies was done. The methodologic quality of each study that met the inclusion criteria was assessed. The results of individual studies were described. The pooled sensitivity and specificity were calculated. Estimation of the diagnostic accuracy was done using meta-regression of the diagnostic odds ratio and summarized by a summary receiver-operating curve (S-ROC). Results: In total, 32 studies (n = 11054) met the inclusion criteria. The overall sensitivity and specificity at the optimum cutoff point are 81% (95% confidence interval: 0.76–0.86) and 86% (95% confidence interval: 0.81–0.89), respectively. The area under the S-ROC for all studies is 0.92. Nine papers included patients with dyspnea. The pooled negative likelihood ratio for this group was 0.12. Five studies included patients with chronic CHF and another seven studies included patients who were referred for echocardiography. The remaining studies were patients from the general population, patients with stable coronary artery disease, and patients referred for cardiac catheterization. Conclusion: BNP is a valuable tool in the diagnosis of CHF. It should be applied in the appropriate clinical setting. The strongest evidence of benefit for use of BNP is in patients presenting to the emergency room with dyspnea.
Subtle population structuring found within northern long-eared bats (Myotis septentrionalis) inhabiting mainland Atlantic Canada

i Acknowledgements ii List of Figures iv List of Tables v Chapter 1: Subtle population structuring found within northern long-eared bats 1 (Myotis septentrionalis) inhabiting mainland Atlantic Canada: Introduction Chapter 2: Genetic analysis reveals subtle population structure and differences in 18 movement behaviour between female and male northern long-eared bats (Myotis septentrionalis) Abstract 19 Introduction 19 Materials and Methods 22 Results 30 Discussion 38 Chapter 3: Subtle population structuring found within northern long-eared bats 56 (Myotis septentrionalis) inhabiting mainland Atlantic Canada: Conclusion
Acceptance Double Sampling Plan with Fuzzy Parameter

In this present paper we have argued the acceptance double sampling plan when the fraction of defective items is a fuzzy number. we have shown that the operating characteristic (oc) curves of the plan is like a band having a high and low bounds whose width depends on the ambiguity proportion parameter in the lot when that sample size and acceptance numbers is fixed. Finally we completed discuss opinion by a numerical example.
Engaging with Mathematics in the Digital Age

There is widespread acceptance that mathematics is important, for an individual and for society. However there are still those who disagree arguing that the subject is boring and irrelevant. It is therefore crucial that mathematics teaching strives to engage all learners at all levels, without of course sacrificing the rigour and ‘essence’ of the subject. In this talk, I will argue that one way to achieve both rigour and broader access to mathematics lies with using appropriately designed digital technology. I will illustrate my argument with examples from research and practice.
Relationships between anchovy (Engraulis encrasicolus L.) recruitment and the environment in the Bay of Biscay

SUMMARY: Oceanographic conditions in spring and summer, caused by northerly-easterly winds of medium and low intensity, in the Bay of Biscay seem to induce good levels of recruitment to the anchovy population. This wind regime produces upwelling conditions with, generally, low degrees of turbulence. Indices of upwelling and turbulence were built and proved significantly correlated with an index of annual recruitment of anchovy (p<0.0001). Both physical parameters explain about 70% of the variance in the index of recruitment of the Bay of Biscay anchovy. The likely explanations for this relationship are outlined and discussed in the light of the current hypotheses about the processes determining recruitment of marine populations. Enhancement of the productivity and increased availability of food to the early life history stages of anchovy seem to be the main consequence of the prevalence of weak upwelling conditions in this area during spring.
Organisational commitment and job embeddedness of service staff with critical and scarce skills

In the light of the global skills shortage, the retention of staff with critical and scarce skills has become a top priority. The objective of this study was to empirically investigate the relationship between such employees' organisational commitment (measured by the Organisational Commitment Questionnaire) and their job embeddedness (measured by the Job Embeddedness Scale). It also attempted to establish whether gender, race, marital status, tenure and job level groups differ significantly regarding these variables in the South African context. A cross-sectional survey design was used to collect data from a purposive sample of N = 206 staff members identified as possessing critical and scarce skills in a South African medical and IT services company. Descriptive, correlational and inferential statistics were applied to achieve the objectives. The participants showed a high level of affective and continuance commitment with regard to their perceived job embeddedness. The results also confirmed that the biographical groups differed significantly in terms of the variables. The results are of importance for managers interested in retaining staff that have been identified as having critical and scarce skills and could provide valuable pointers for the design of effective human resource retention strategies.
Association Rules based Approach for Generating Informative ESP Game Labels

- Games with a purpose (GWAP) and microtask crowdsourcing are considered two techniques of the human-computation. Image Retrieval (ImR) is an important field for every user. Every day hundreds of users go through the web sites and search for images matching given criteria. Many researchers focus on making the ImR systems more accurate. The using of GWAPs in ImR systems will make them more accurate and useful. They provide the ImR system’s database with a rich of information by adding more descriptions and annotations to images. One of the systems of human-computation is ESP Game. ESP Game is a type of games with a purpose. In the ESP game, there has been a lot of work was proposed to solve many of the problems of it and makes the most benefit of the game. One of the problems of the ESP game is that it encourages players to assign “obvious” labels, which are most likely to lead to an agreement with the partner. This paper presents a new approach for generating informative ESP game labels with no need to extra un-useful game round between players using association rules mining. The results show that new informative labels can be generated automatically without any interference of extra game rounds or any human.
Exact form of the exponential Foldy-Wouthuysen transformation operator for an arbitrary-spin particle

The exact exponential Foldy-Wouthuysen transformation operator applicable for a particle with an arbitrary spin is derived. It can be successfully utilized for verifying any Foldy-Wouthuysen transformation method based on the exponential operator. When a verified method is relativistic, the relativistic exponential operator should be expanded in the semirelativistic power series. The use of the obtained exponential operator for a derivation of the Foldy-Wouthuysen Hamiltonian makes it possible to check the validity of any other method of the Foldy-Wouthuysen transformation, while this possibility may need a greater computational effort.
OBSERVATIONAL SELECTION EFFECTS AND THE M–σ RELATION

We examine the possibility that the observed relation between black hole mass and host-galaxy stellar velocity dispersion (the M–σ relation) is biased by an observational selection effect, the difficulty of detecting a black hole whose sphere of influence is smaller than the telescope resolution. In particular, we critically investigate recent claims that the M–σ relation only represents the upper limit to a broad distribution of black hole masses in galaxies of a given velocity dispersion. We find that this hypothesis can be rejected at a high confidence level, at least for the early-type galaxies with relatively high velocity dispersions (median 268 km s−1) that comprise most of our sample. We also describe a general procedure for incorporating observational selection effects in estimates of the properties of the M–σ relation. Applying this procedure we find results that are consistent with earlier estimates that did not account for selection effects, although with larger error bars. In particular, (1) the width of the M–σ relation is not significantly increased, (2) the slope and normalization of the M–σ relation are not significantly changed, and (3) most or all luminous early-type galaxies contain central black holes at zero redshift. Our results may not apply to late-type or small galaxies, which are not well represented in our sample.
Analysis of the thermal physiology of the Andean lizard Stenocercus festae (Squamata: Iguanidae: Tropidurinae) to predict possible extinctions in their populations due to climate change

We studied the thermal physiology of the Andean lizard Stenocercus festae, a thermoregulatory lizard that inhabits sub-Andean forests at southern Ecuador, to address the potential effects of climate change on its populations. Experimental data showed that the preferred body temperature (Tpref) was 21.79 C, the minimum critical thermal (CTmin) was 6.20 C, and the maximum critical thermal (CTmax) was 46.24 C. We applied the model for thermoregulatory lizards proposed by Sinervo et al. (2010) that integrates georeferenced points of species distribution, the Tpref obtained in the field, the lowest temperature at which lizards are active (Tact), the operative temperature (Te), and daily maximum air temperature to get the number of hours of restriction (Hr, the number of hours per day when Te exceeded Tpref) and hours of activity (Because this model was not suitable for this species, we modified it by proposing three different scenarios of Tpref and Tact values, as well as by changing the way we predict extinctions from restriction hours. Both modifications predicted that on 2010, 13.8% of the populations had already gone extinct, including the population of study; by 2020, 60% of the populations that went extinct in 2010 will probably recover by recolonization. Warming tolerance (WT), compared with a closely related species, showed that S. festae tolerates higher temperatures than S. guentheri because it presents a wider difference between its CTmax and the average and maximum Tair, as well as a wider thermal tolerance breadth.
Extending Recommender System by Incorporating Semantic-social Information

Recommender systems in e-commerce applications have become business relevant in filtering the vast range of information available in web shop (and the internet) to present useful recommendation to user. In this study we combine social network analysis and semantic user profile to provide a new semantic-social recommendation, featuring a two-stage process that relies on a simple formalization of semantic user preferences that contains the user's main interests and heuristically explores the social graph. Given a recommendation request concerning a product, the semantic-social recommendation algorithm compares the user preferences, which are found in the exploration path, with the product preferences by referencing them to domain ontology. Experiments on real-world data from Amazon, examine the quality of our recommendation method as well as the efficiency of our recommendation algorithms.
The serotonin transporter gene ( SLC 6 A 4 ) shows differential regulation between children with ASD and typically developing children in a South African population

iii LIST OF FIGURES . vi LIST OF TABLES . vi CHAPTER 1: Introduction . 1 1.1. Complex phenotypes and Autism Spectrum Disorders (ASD) . 1 Challenges of studying ASD: heterogeneity and heritability. 2 1.2. Genetic/Epigenetic interplay . 4 DNA methylation . 5 Candidate genes/pathways . 6 1.3. Serotonergic signalling and the serotonin transporter (SLC6A4) . 7 Link to ASD . 8 Repeat polymorphism of SLC6A4 . 9 Promoter DNA methylation of SLC6A4 . 11 1.4. Research question and study aims . 14 CHAPTER 2: Methods and Materials . 16 2.1. Sample cohort and phenotypic information . 16 Buccal cell collection and genomic DNA extraction . 17 2.2. Genetic methodology: SLC6A4 polymorphisms . 18 Repeat polymorphism and SNP rs25531 . 18 2.3. Epigenetic methodology: DNA methylation. 19 2.3. 1. Qualitative analysis . 19 Bisulphite converted DNA sequencing . 19 Native DNA sequencing . 20 2.3. 2. Quantitative analysis . 21 EpiTYPER MassARRAY methylation assay . 21 2.4. Statistical analysis . 23