Miracle-dz/UniFAR-FTUs huggingface dataset:
Wideband Dual-Polarized Binary Coding Antenna With Wide Beamwidth and Its Array for Millimeter-Wave Applications

A novel millimeter-wave (mm-Wave) binary coding antenna with broadband, dual-polarization, and wide beamwidth is proposed, and its broad-angle scanning array is also studied. The element employs the stacked patches, where the optimal middle parasitic patch and top driven patch are introduced to broaden the bandwidth and beamwidth. The driven and parasitic patches are realized by series of small units optimized by binary code. The measured results for the proposed antenna prototype agree well with the simulated ones, showing a wide impedance bandwidth and good port isolation from 21.8 to 33.2 GHz (FBW = 41.5%). The measured half-power beamwidth is between 128<inline-formula><tex-math notation="LaTeX">$^{\circ }$</tex-math></inline-formula> and 157<inline-formula><tex-math notation="LaTeX">$^{\circ }$</tex-math></inline-formula> over the operating bandwidth. The element was then extended to an eight-element phased array. The measured results demonstrate that the array with a broad scanning angle more than 100<inline-formula><tex-math notation="LaTeX">$^{\circ }$</tex-math></inline-formula> over the available band can be achieved.
Effect of Tramadol Versus Fentanyl on Some Hematological and Serum Biochemical Parameters in Dogs

The present study was designed to compare between the effect of tramadol Hcl and fentanyl citrate on some hematological and serum biochemical parameters in dogs. For this purpose, ten adult mongrel dogs were randomly allocated into two equal groups: Group ɪ; dogs received tramadol hydrochloride 2 mg kg-1 IV; Group ɪɪ; dogs received fentanyl citrate 5 µg kg-1 IV. The measured hematological variables were: red blood cell count, packed cell volume, hemoglobin concentration, total leucocytic count, differential leucocytic counts and platelet count. Serum samples were assessed for concentrations of total protein, albumin, glucose, urea, creatinine and serum enzymatic activities of alanine and aspartate transaminases. All parameters were recorded at baseline, following administration of analgesic agents (0 time) and for 1.5 hour later at 15 minutes interval. Data were analyzed using a paired- samples t-test (p < 0.05). As a result, tramadol induced a significant (p < 0.05) decrease in total leukocytic and neutrophil counts while, a significant (p < 0.05) increase in total leucocytic, lymphocyte and neutrophil counts were recorded at some time periods in fentanyl group. Blood platelets significantly increased in both groups. Serum urea levels significantly increased in tramadol group while, in fentanyl group, at some periods it showed a significant (p < 0.05) decrease as well as creatinine. Red cell parameters as well as other serum biochemical parameters did not show any significant changes in both group. It was concluded that, Fentanyl might have some virtues on leukogarm and some biochemical parameters in dogs. Subsequently, its use may be advantageous over tramadol for canine patient suffering from leukopenia and renal disorders.
Blood Pressure Control Status of Hypertensive Patients Attending an Out-Patient Specialist Clinic in Ghana

Hypertension is a major cardiovascular disease risk factor, yet with availability of innovative and effective medical therapy its control is still a huge challenge in sub-Saharan Africa including Ghana. We undertook a cross-sectional study among hypertensive patients attending an out-patient specialist clinic in a semi-urban community in Ghana to determine blood pressure control rate and characterize antihypertensive medication use among the patients. Three hundred and fifty four (354) hypertensive patients aged between 23 - 79 years with the mean age (± SD) of 46.9 (± 12.1) years were studied. The mean duration of hypertension was 5.5 years (range 1 month to 45 years). Two hundred and sixteen (61.02%) of the patients were prescribed one antihypertensive, 53(14.97%) were prescribed two antihypertensives and 3 (0.85%) were prescribed three antihypertensives; with antihypertensive class being calcium channel blockers in 76.2% of the patients, beta-blockers in 11.4% of the patients, centrally acting agents in 6.9 % of the patients, and angiotensin-converting enzyme (ACE) inhibitors in 3.0% of the patients. The commonest calcium channel blocker, ACE inhibitor and beta-blocker prescribed were nifedipine, lisinopril, and atenolol respectively. One hundred and thirty-eight (39.0%) patients had adequate blood pressure control. Among patients with poor blood pressure control, 74 (34.3%) had blood pressure >160/l00mmHg (hypertension stage II). In conclusion, our study shows that majority of the hypertensive patients studied had poorly controlled blood pressure which indicates a higher future burden of cardiovascular diseases.
DeepCropNet: a deep spatial-temporal learning framework for county-level corn yield estimation

Large-scale crop yield estimation is critical for understanding the dynamics of global food security. Understanding and quantifying the temporal cumulative effect of crop growth and spatial variances across different regions remains challenging for large-scale crop yield estimation. In this study, a deep spatial-temporal learning framework, named DeepCropNet (DCN), has been developed to hierarchically capture the features for county-level corn yield estimation. The temporal features are learned by an attention-based long short-term memory network and the spatial features are learned by the multi-task learning (MTL) output layers. The DCN model has been applied to quantify the relationship between meteorological factors and the county-level corn yield in the US Corn Belt from 1981 to 2016. Three meteorological factors, including growing degree days, killing degree days, and precipitation, are used as time-series inputs. The results show that DCN provides an improved estimation accuracy (RMSE = 0.82 Mg ha−1) as compared to that of conventional methods such as LASSO (RMSE = 1.14 Mg ha−1) and Random Forest (RMSE = 1.05 Mg ha−1). Temporally, the attention values computed from the temporal learning module indicate that DCN captures the temporal cumulative effect and this temporal pattern is consistent across all states. Spatially, the spatial learning module improves the estimation accuracy based on the regional specific features captured by the MTL mechanism. The study highlights that the DCN model provides a promising spatial-temporal learning framework for corn yield estimation under changing meteorological conditions across large spatial regions.
Differential Expression of MiR-18b in PBMC from T1D Patients in Isfahan population

Corresponding Author: Zohreh Hojati Division of Genetics, Department of Biology, Faculty of Sciences, University of Isfahan, Isfahan, Iran. Phone: +983117932478 E-mail: z.hojati@sci.ui. ac.ir Abstract Background: Type 1 diabetes (T1D) is caused by cell-mediated autoimmune attack on pancreatic beta cells. Previous studies highlight the role of microRNAs (miRNAs) in the pathogenesis of T1D. MiRNAs are small non-coding RNAs involved in the regulation of gene expression post-transcriptionally. In this work, microRNA-18b (miR-18b) was chosen and its differential expression was measured between T1D patients and healthy controls from Isfahan population. Materials and Methods: miR-18b was selected according to bioinformatic studies using miRWalk software. 22 T1D patients and 18 healthy controls from Isfahan population were enrolled in this study. Total RNA of the peripheral blood mononuclear cell (PBMC) samples was extracted. After cDNA synthesis, the expression profile of miR-18b was quantified by means of qPCR method in patients and controls. Finally, the results were statistically analyzed. Results: In this study despite our hypothesis, the expression levels of miR-18b didn’t show any significant difference between T1D patients and healthy controls (p value: 0.145). Conclusion: Due to the results of our experimental analysis, it seems that miR18b doesn’t have any association with T1D disease in Isfahan population.
Impact des défauts d'aspect sur la propagation d'un laser de puissance

Chaque faisceau d'un laser de puissance, tel que le Laser MegaJoule, est mis en forme et voit son energie amplifiee a l’aide d’une centaine de composants optiques tels que des plaques de verre amplificateur, des lentilles, des miroirs, des lames de phase, des reseaux. 'Evidemment ces composants ne sont pas parfaitement realises et ils presentent a leurs surfaces des defauts de fabrication. Ces imperfections peuvent etre dues aux outils de polissage des composants, aux depots antireflet ou meme apparaitre au cours de la phase d’exploitation ou de remediation du composant. Ces defauts contribuent a une baisse des performances du Laser MegaJoule que ce soit au niveau de l’energie deposee au centre de la chambre d’experiences ou a l’endommagement accelere des composants optiques places en aval. Actuellement la norme ISO 10110-7 est utilisee pour specifier les defauts d’aspect. Cependant elle manque de justification pour les besoins d’une chaine laser de puissance. Dans le cadre de la these nous nous interessons exclusivement a l’endommagement fratricide local des composants optiques. Un defaut present a la surface du composant module l’onde lumineuse par phenomene de diffraction. Un > peut apparaitre dans le faisceau laser augmentant alors la densite locale surfacique d’energie appliquee aux composants suivants. La loi d’endommagement predit une augmentation de la probabilite d’endommagement puisque la densite d’energie est modifiee. Une premiere etude, fondee sur les equations de Fresnel, met en evidence les parametres interessants a specifier pour predire les intensifications engendrees par des defauts typiques. Le lien entre parametres du defaut et intensifications diffractees est, ensuite, validite experimentalement sur des cas reels de defauts. Une seconde etude etablit un seuil exprime en puissance en deca duquel l'hypothese d'une propagation lineaire, selon les equations de Fresnel, est valide. La coherence des resultats donnes par le seuil en puissance et par la simulation numerique renforce l’idee voulant que la propagation d’un > en presence d'effet Kerr soit sensiblement differente de celle d’un faisceau gaussien. Fort de ces deux resultats nous sommes en capacite d'etablir une specification des defauts d’aspect en ayant une meilleure comprehension de l’endommagement fratricide local.
Efficiency of distance measures in the automatic grouping of electronic radio devices by k-means algorithm

This study investigates the problem of separation mixed lot of semiconductor devices for space applications into homogeneous production batches. The impact of distancemeasures in clustering algorithmk-means on the accuracy of the separating a mixed production batch is studied. This paper proposes the K-means algorithm withsquared Mahalanobis distance as an alternative the squared Euclidean distance. With the various combined mixed lots of semiconductor devices it was shown, that the proposed squared Mahalanobis distance highly depends on the method for determining initial cluster centers.
A phase II trial of the histone deacetylase inhibitor belinostat (PXD101) in patients with platinum resistant epithelial ovarian tumors and micropapillary/borderline (LMP) ovarian tumors. A PMH phase II consortium trial

5518 Background: Patients with LMP ovarian tumors represent an understudied population whose tumors are intrinsically resistant to radiation and chemotherapy. Patients with platinum resistant epithelial ovarian cancer (EOC) have low response rates to conventional chemotherapy. Histone deacetylation results in loss of tumor suppressor and pro apoptotic genes in ovarian cancer cell lines. Belinostat is a pan hydroxamate, histone deacetylase inhibitor which demonstrates anti tumor activity in ovarian cancer models Methods: The aim of this phase II study is to assess the activity of belinostat in 2 patient populations: metastatic or recurrent platinum resistant (< 6 mo) EOC and LMP ovarian tumors. 3 prior lines of chemotherapy were allowed. Primary endpoints are objective response with a multinomial stopping rule, secondary endpoints include stable disease (SD) rate, survival, tolerability and assessment of molecular changes with therapy. Belinostat 1,000mg/m2/day was administered iv on days 1–5 of a 21 day c.
Value of Technical Wear and Costs of Restoring Performance Characteristics to Residential Buildings

Each building, over the course of subsequent years of use, undergoes wear, with a deterioration of its technical condition. As a result of this, the performance characteristics of a building decrease with the passing of time, with their complete or partial restoration requiring repair and renovation works to be carried out. It is the task of real estate managers or owners to maintain the building in a non-deteriorating technical and functional condition. In order to preserve the technical and functional condition of a building at an adequate level, methodological support of decision-making processes pertaining to the conducting of rational maintenance management is necessary. The present article presents a proposal of a model allowing for the accurate assessment of the costs of renovation and repair works on a building at a given stage of its use, and their relationship with the value of the technical wear of the building in the same time period. Residential buildings constructed using traditional technology were subjected to analysis. In the carried out analysis, temporal methods applied for calculating the level of technical wear were applied, with the PRRD (prediction of reliability according to Rayleigh distribution) model of changes in the performance characteristics applied to determine the costs of renovation works necessary for restoring performance characteristics to the building.
Selectorate’s information and dictator’s accountability

In this paper, we study the evolution of accountability in autocracies and the consequent progressive economic and political mismanagement in terms of information changes. It is often held to be true that better information means greater accountability. On the contrary, we show that in dictatorships, better information might imply worse choices by a dictator. The basic idea is that the reputation mechanism underlying accountability only works if there is enough noise surrounding the dictator’s possible type. As the selectorate’s information about the dictator’s actual type increases over time, the incentives for the dictator to behave correctly vanish.
Correlation Effects? A Major but Often Neglected Component in Sensitivity and Uncertainty Analysis

Global sensitivity analysis (GSA) provides essential insights into the behavior of Earth and environmental systems models and identifies dominant controls of output uncertainty. Previous work on GSA, however, has typically been under the assumption that the controlling factors such as model inputs and parameters are independent, whereas, in many cases, they are correlated and their joint distribution follows a variety of forms. Although this assumption can limit the credibility of GSA and its results, very few studies in the field of water and environmental modeling address this issue. In this paper, we first discuss the significance of correlation effects in GSA and then propose a new GSA framework for properly accounting for correlations in input/parameter spaces. To this end, we extend the “variogram‐based” theory of GSA, called variogram analysis of response surfaces (VARS), and develop a new generalized star sampling technique (called gSTAR) to accommodate correlated multivariate distributions. We test the new gSTAR‐VARS method on two test functions, against a state‐of‐the‐art GSA method that handles correlation effects. We then apply gSTAR‐VARS to the HBV‐SASK model, calibrated via a Bayesian, Markov chain Monte Carlo approach, for design flood estimation in the Oldman River Basin in Canada. Results demonstrate that accounting for correlation effects can be critically important in GSA, especially in the presence of nonlinearity and interaction effects in the underlying response surfaces. The proposed method can efficiently handle correlations and different distribution types and simultaneously generate a range of sensitivity indices, such as total‐variogram effects, variance‐based total‐order effects, and derivative‐based elementary effects.
Beyond the Breakfast Club: Variability in the Effects of Suspensions by School Context

Rather than mitigating behavioral issues, exclusionary school disciplinary practices can actually increase student misbehavior and school dropout. However, the impact these sanctions have on students may vary based on school climate, particularly whether the environment is inclusive or punitive. Relying on a sample of over 2,000 students within 26 schools, we examine whether school climate shapes the impact of suspension on future delinquency and later school sanctions. We find that suspension is associated with increased misbehavior and additional sanctioning, regardless of school climate. These results suggest that suspensions can cause harm no matter the environment in which they are meted out, and schools should work to reduce their use of exclusionary punishments.
Effort estimation of open source Android projects via transaction analysis

Transactions have been used in many software sizing methods to measure software functional size and provide a basis for effort estimation. To further investigate the effects that transactions have on software functional size and more accurately estimate project effort using the transactional information, in this paper, we propose a method to identify transactions, as well as their complexity attributes that are influential to software functional size, directly from the source code of Android projects using static and dynamic analyses.
Optimising Cardiopulmonary Bypass Utilizing Continuous Oxygen Saturation Monitoring

Proper management of cardiopulmonary bypass requires the analysis of both arterial and venous blood gases at regular intervals, and is most critical during the rewarming phase. 3,4 In some hospitals blood gas results are received as long as 15 to 30 minutes after the sample is drawn. More frequent blood gas analysis or ideally continuous measurement of oxygen saturation allows the perfusionist to make continuous adjustments as the patient’s oxygen requirements change. Two hundred patients were selected for study. One hundred were perfused using regular periodic blood analyses. A second group of one hundred patients were perfused utilizing an in-line saturation meter. The blood flow rate was 6% lower during hypothermia and 5% lower while warm in the group utilizing the saturation meter. The total gas flow rate was reduced by 20% while cold and 16% while warm in the metered group. The CPB arterial and venous pO2 RANGES were reduced with the use of the oxygen saturation meter. The same make of hybrid oxygenator was utilized on all patients in both study groups. Based on the close correlation of the oxygen saturations afforded by the saturation meter and those measured by the blood gas laboratory, we found the Bentley Oxygen Saturation Meter reliable and accurate. It may help protect the patient from extremes in oxygenation and allows the perfusionist to regulate the oxygenator in the most precise and efficient operation.
Profiling of chromatin accessibility across Aspergillus species and identification of transcription factor binding sites in the Aspergillus genome using filamentous fungi ATAC-seq

To identify cis-regulatory elements (CREs) and motifs of TF binding is an important step in understanding the regulatory functions of TF binding and gene expression. The lack of experimentally determined and computationally inferred data means that the genome-wide CREs and TF binding sites (TFBs) in filamentous fungi remain unknown. ATAC-seq is a technique that provides a high-resolution measurement of chromatin accessibility to Tn5 transposase integration. In filamentous fungi, the existence of cell walls and the difficulty in purifying nuclei have prevented the routine application of this technique. Herein, we modified the ATAC-seq protocol in filamentous fungi to identify and map open chromatin and TF-binding sites on a genome-scale. We applied the assay for ATAC-seq among different Aspergillus species, during different culture conditions, and among TF-deficient strains to delineate open chromatin regions and TFBs across each genome. The syntenic orthologues regions and differential changes regions of chromatin accessibility were responsible for functional conservative regulatory elements and differential gene expression in the Aspergillus genome respectively. Importantly, 17 and 15 novel transcription factor binding motifs that were enriched in the genomic footprints identified from ATAC-seq data of A. niger, were verified in vivo by our artificial synthetic minimal promoter system, respectively. Furthermore, we first confirmed the strand-specific patterns of Tn5 transposase around the binding sites of known TFs by comparing ATAC-seq data of TF-deficient strains with the data from a wild-type strain.
Representing and Redefining Specialised Knowledge: Medical Discourse

Although titling is traditionally a lexically and textually prominent operation, performing key informative/persuasive/promotional functions in discourse domains such as advertising and entertainment, the spread of Web-based communication has increased its importance with respect to practices farther away on a discoursal spectrum from such functions as medical communication. The inception of the Internet as the main channel for knowledge dissemination has brought about significant changes in the titling of highly specialized discourse. Medical RA titles (RATs) seem, as a genre, to provide insights into the impact of digital literacy on scientific knowledge. In order to explore such changes, a total of 1250 RATs from the British Medical Journal – the world’s first online medical journal – were collected from a 20-year period, and analysed with AntConc and Wordsmith Tools. The RATs in the corpus trace the history of the Human Immunodeficiency Virus from 1985, when the first WHO conference on AIDS was held in the USA, until 2005. The paper analyses and contrasts print vs. digital RATs, identifying and quantifying the key syntactical/textual patterns and variations in a genre whose main function is to package/textualize scientific contents (including competing clinical methodologies), as well as to disseminate them across specialized and/or lay audiences. Research questions concern the extent to which the language of RATs has been changing with respect to the dissemination triggered by digital literacy, from crystallised and gatekeeping formulations to more articulated ones, placing distinctive emphasis on argumentative/persuasive/metadiscoursive functions, as well as the impact of EvidenceBased Medicine – today’s leading paradigm for scientific knowledge, first presented in BMJ in 1995 – on contemporary HIV discourse.
Bevorzugte Report Items für systematische Übersichten und Meta-Analysen: Das PRISMA-Statement

Systematische Übersichten und Meta-Analysen sind in der medizinischen Versorgung immer wichtiger geworden. Kliniker halten sich damit in ihrem Arbeitsgebiet auf dem Laufenden [28, 32]. Außerdem werden sie oft als Ausgangspunkt für die Entwicklung von klinischen Leitlinien eingesetzt. Drittmittelgeber fordern möglicherweise systematische Übersichten als Rechtfertigung für weitere Forschungsvorhaben [7], und auch einige medizinische Fachzeitschriften entwickeln sich in diese Richtung [42]. Der Nutzen einer systematischen Übersichtsarbeit hängt wie bei jeder Forschung davon ab, was gemacht wurde, was die Ergebnisse waren, und wie klar der Bericht ist. Da die Qualität der Reports systematischer Übersichten ebenso wie bei anderen Publikationen variiert, können Leser die Stärken und Schwächen dieser Arbeiten nicht immer vollständig erfassen.