Miracle-dz/UniFAR-FTUs huggingface dataset:
Single Versus Repeated Sessions of Ketamine-Assisted Psychotherapy for People with Heroin Dependence

Abstract A prior study found that one ketamine-assisted psychotherapy session was significantly more effective than active placebo in promoting abstinence (Krupitsky et al. 2002). In this study of the efficacy of single versus repeated sessions of ketamine-assisted psychotherapy in promoting abstinence in people with heroin dependence, 59 detoxified inpatients with heroin dependence received a ketamineassisted psychotherapy (KPT) session prior to their discharge from an addiction treatment hospital, and were then randomized into two treatment groups. Participants in the first group received two addiction counseling sessions followed by two KPT sessions, with sessions scheduled on a monthly interval (multiple KPT group). Participants in the second group received two addiction counseling sessions on a monthly interval, but no additional ketamine therapy sessions (single KPT group). At one-year follow-up, survival analysis demonstrated a significantly higher rate of abstinence in the multiple KPT group. Thirteen out of 26 subjects (50%) in the multiple KPT group remained abstinent. compared to 6 out of 27 subjects (22.2%) in the single KPT group (p < 0.05). No differences between groups were found in depression, anxiety, craving for heroin, or their understanding of the meaning of their lives. It was concluded that three sessions of ketamine-assisted psychotherapy are more effective than a single session for the treatment of heroin addiction.
Sodium currents in the myelinated nerve fibre of Xenopus laevis investigated with the voltage clamp technique

It has previously been shown (Dodge & Frankenhaeuser, 1958) that the nodal membrane of frog nerve fibres responds to stepwise changes of membrane potential with a flow of current strikingly similar to that which occurs in the squid giant axon (Hodgkin & Huxley, 1952 a, b, c, d; Hodgkin, Huxley & Katz, 1952). A cathodal step is associated with an initial transient current followed by a delayed lasting outward current. The variation of the amplitude of the initial current with membrane potential, the definite potential at which the initial current changes direction, the dependence of this potential on the external sodium ion concentration, and the variation of the nodal action potential with sodium concentration (Huxley & Stampfli, 1951), suggest that the initial current of the nodal membrane is indeed a sodium current, as it is in the squid giant axon (Hodgkin & Huxley, 1952 a). In the present investigation it will be shown that the effect of changing the external sodium ion concentration is quantitatively consistent with the idea that the nodal membrane, when depolarized, undergoes a transient large increase in its sodium permeability, that this permeability depends on the membrane potential, but not on the sodium concentration, and that the initial current is a flow of sodium ions moving passively down the electrochemical gradient for sodium. Further quantitative analysis of the voltage clamp data will be published later.
Influence of CT-based attenuation correction in assessment of left and right ventricular function w ith count-based gated blood-pool SPECT CT-AC and GBPS

Objective: Influence of CT-based attenuation correction (CT-AC) in assessment of left and right ventricular function with count-based gated blood-pool SPECT (GBPS) was evaluated in a mixed population. Methods: Thirty-two patients (81% male; mean age 56 ±12) referred for various symptoms or heart diseases were prospectively included. Data from 32 GBPS acquisitions were reconstructed using an iterative algorithm with and without CT-AC and analyzed using previously described segmentation software based on the watershed algorithm. LV and RV EF and volumes were assessed with and without CT-AC and compared. Results: EF and volumes were correlated (p<0.001). Significant differences were found for all parameters, with higher volumes (p<0.001 except for RV EDV, p=0.002) and lower EF(p=0.002 for LV EF and p<0.001 for RV EF) when using CT-AC. Limits of agreement were -11 to 6% and -11 to 4% for LV and RV EF. We found wider limits of agreement for LV volumes (-13 to 32 mL for EDV and -10 to 27 mL for ESV) than for RV volumes (-13 to 23 mL for EDV and -9 to 20 mL for ESV). Taking into account all volumes, we found a trend with a significant positive correlation between means and differences in volumes assessed with and without CT-AC. Conclusion: Assessment of both left and right ventricular function by count-based GBPS with CT-AC showed higher volumes and lower EF. Differences were very slight, especially for the range of normal to subnormal ventricular volumes, and the clinical interest of CT-AC is to be demonstrated.
DESCRIPTION OF BUCKAROOTREMA GOODMANI N. G., N. SP. (DIGENEA: PRONOCEPHALIDAE), A PARASITE OF THE FRESHWATER TURTLE EMYDURA MACQUARII (GRAY, 1830) (PLEURODIRA: CHELIDAE) FROM QUEENSLAND, AUSTRALIA, AND A PHYLOGENETIC ANALYSIS OF THE GENERA OF THE PRONOCEPHALIDAE LOOSS, 1902

Buckarootrema goodmani n. g. , n. sp. is described from the small intestine of the Murray turtle, Emydura macquarii (Gray, 1830), from the vicinity of Warwick, Queensland, Australia. The distinctive taxonomic features include the vitellarium, which consists of 2 compact masses directly anterior to and occasionally overlapping the testes; the uterus with extensive pre- and postovarian coils; intestinal ceca with small, medial diverticula that terminate anterior to or at the anterior margin of the testes; a comma-shaped cirrus sac with both internal and external seminal vesicles. Phylogenetic systematic analysis of the genera of the Pronocephalidae including Buckarootrema and Notopronocephalus, the only other genus of pronocephalids reported from Australian freshwater turtles, indicates that Buckarootrema is the sister taxon of Neopronocephalus and Notopronocephalus is the sister group of the rest of the Pronocephalinae.
Biodegradation of phenol and benzene by endophytic bacterial strains isolated from refinery wastewater-fed Cannabis sativa

ABSTRACT The presence of benzene and phenol in the environment can lead to serious health effects in humans and warrant development of efficient cleanup strategies. The aim of the present work was to assess the potential of indigenous endophytic bacterial strains to degrade benzene and phenol. Seven strains were successfully isolated from Cannabis sativa plants irrigated with oil refinery wastewater. Molecular characterization was performed by 16S rRNA gene sequencing. Phenol was biodegraded almost completely with Achromobacter sp. (AIEB-7), Pseudomonas sp. (AIEB-4), and Alcaligenes sp. (AIEB-6) at 250, 500, and 750 mg L−1; however, the degradation was only 81%, 72%, and 69%, respectively, when exposed to 1000 mg L−1. Bacillus sp. (AIEB-1), Enterobacter sp. (AIEB-3), and Acinetobacter sp. (AIEB-2) degraded benzene significantly at 250, 500, and 750 mg L−1. However, these strains showed 80%, 72%, and 68% benzene removal at 1000 mg L−1 exposure, respectively. Rates of degradation could be modeled with first-order kinetics with rate constant values of 1.86 × 10−2 for Pseudomonas sp. (AIEB-4) and 1.80 × 10−2 h−1 for Bacillus sp. (AIEB-1) and half-lives of 1.5 and 1.6 days, respectively. These results establish a foundation for further testing of the phytoremediation of hydrocarbon-contaminated soils in the presence of these endophytic bacteria.
Evaluation of the Clinical Performance of High-Risk Human Papillomavirus Testing for Primary Screening: A Retrospective Review of the Southern California Permanente Medical Group Experience

Objective: We investigated the potential impact of using the high-risk human papillomavirus (HPV) test as a primary screening tool for the detection of cervical cancer and its precursor lesions. Materials and Methods: From October 2005 to March 2006, conventional cervical cytological samples and Hybrid Capture II HPV tests were cocollected from all patients. Human papillomavirus tests were processed in all women aged 30 years and older and women younger than 30 years with a cytological finding of atypical squamous cells of undetermined significance. Patients with biopsy-proven cervical intraepithelial neoplasia (CIN) served as the study population. Results: We identified 263 women with CIN of whom 194 (73.8%) (95% confidence interval [CI] = 68.2%-78.8%) had HPV results. Human papillomavirus tests were negative in 4 (6.1%) of 66 CIN 3 cases (95% CI = 2.1%-14.5%), in 8 (16%) of 50 CIN 2 cases (95% CI = 7.3%-28.2%), and in 22 (22.8%) of 78 CIN 1 cases (95% CI = 18.6%-38.9%) distributed across all referral cytology categories. Negative HPV test rates were most significant for CIN 1 cases anteceded by a cytological finding of atypical squamous cells of undetermined significance (p =.0016). The mean age of women with HPV-negative CIN was 10 years older than that for women with HPV-positive CIN. Conclusions: Human papillomavirus testing may miss more CIN than previously reported, especially in older women. Prospective trials of HPV testing as a primary screen for cervical cancer should incorporate additional tests to minimize missed lesions.
Architecting millisecond test solutions for wireless phone RFICs

Today's low cost wireless phones have driven a need to be able to economically test high volumes of complex RF ICs at a fraction of the cost of the IC. In June of 2001 the IBM test development group developed a strategy and design to test complex wireless phone front end components for a fraction of the cost of using traditional ATE or rack and stack test solutions. In this paper, the architecture of the system is described as well as some of the design, maintenance and implementation considerations. The system is designed to bring the cost of complex manufacturing test of RF ICs equivalent to that of testing discrete components such as resistors or capacitors. Given the drastic reduction of test cost and the relative ease of implementation of this solution, this architecture sets the bar for future RF test solutions. To the best of our knowledge, this architecture has resulted in the fastest RF tester in the world.
Modified Free Radial Forearm Fascia Flap Reconstruction of Lower Extremity and Foot Wounds: Optimal Contour and Minimal Donor-Site Morbidity

Abstract Background Free tissue transfer is commonly required for reconstruction of distal third lower extremity injuries. Injuries involving the dorsal surface of the foot require thin pliable flaps. Musculocutaneous flaps are often too bulky to accommodate shoewear. Fasciocutaneous flaps, while an improvement, need secondary contouring procedures. The modified radial forearm fascial flap (MRFFF) may offer an alternative. Methods Twelve patients with distal third lower extremity wounds were reconstructed with MRFFF + split thickness skin graft. The modification in flap design leaves fascia radial to the pedicle unharvested, preserving sensibility of the dorsoradial aspect of the hand. Flaps were covered with a skin graft after inset. Donor sites were closed primarily. Results Nine wounds were traumatic—five with exposed hardware, one burn, one diabetic ulcer, and one wound dehiscence following sarcoma resection + radiation. Out of 12, 11 limbs were salvaged at 1 to 2 years follow-up. All patients ambulated on the reconstructed leg and wore a shoe comfortably. Average time to weight bearing was 2 months. The donor site was limited to 25-cm scar on the volar forearm. No persistent motor/sensory deficits occurred in donor arms. Conclusion MRFFF is an excellent flap for reconstruction of the distal lower extremity. Flap contour allows excellent shoe-fitting without secondary revisions. Replacement of the adipocutaneous flap on MRFFF donor site eliminates the need for a conspicuous donor-site skin graft. The ulnar orientation of the harvested fascia prevents sensory loss in the dorsal hand. The MRFFF provides the ideal replacement of “like with like” for selected distal lower extremity wounds.
Validation of the Child Perceptions Questionnaire (CPQ11-14)

While the use of adult oral-health-related quality-of-life (OHRQoL) measures in supplementing clinical indicators has increased, that for children has lagged behind, because of the difficulties of developing and validating such measures for children. This study examined the construct validity of the Child Perceptions Questionnaire (CPQ11-14) in a random sample of 12- and 13-year-old New Zealanders. It was hypothesized that children with more severe malocclusions or greater caries experience would have higher overall (and subscale domain) CPQ11-14 scores. Children (N = 430) completed the CPQ11-14 and were examined for malocclusion (Dental Aesthetic Index) and dental caries. There was a distinct gradient in mean CPQ11-14 scores by malocclusion severity, but there were differences across the four subscales. Children in the worst 25% of the DMFS distribution had higher CPQ11-14 scores overall and for each of the 4 subscales. The construct validity of the CPQ11-14 appears to be acceptable.
Postmortem Program Analysis with Hardware-Enhanced Post-Crash Artifacts

While a core dump carries a large amount of information, it barely serves as informative debugging aids in locating software faults because it carries information that indicates only a partial chronology of how program reached a crash site. Recently, this situation has been signiﬁcantly improved. With the emergence of hardware-assisted processor tracing, software developers and security analysts can trace program execution and integrate them into a core dump. In comparison with an ordinary core dump, the new post-crash artifact provides software developers and security analysts with more clues as to a program crash. To use it for failure diagnosis, however, it still requires strenuous manual efforts. In this work, we propose POMP , an automated tool to facilitate the analysis of post-crash artifacts. More specifically, POMP introduces a new reverse execution mechanism to construct the data ﬂow that a program followed prior to its crash. By using the data ﬂow, POMP then performs backward taint analysis and highlights those program statements that actually contribute to the crash. To demonstrate its effectiveness in pinpointing program statements truly pertaining to a program crash, we have implemented POMP for Linux system on x86-32 platform, and tested it against various program crashes resulting from 31 distinct real-world security vulnerabilities. We show that, POMP can accurately and efﬁciently pinpoint program statements that truly pertain to the crashes, making failure diagnosis signiﬁcantly convenient.
Method of Association Rule Based on Improved Genetic Algorithm and Application of Network Consuming for the Contemporary Youth

Genetic Algorithm and Association Rules both are commonly used methods in data mining. In this paper, a brief overview of Genetic Algorithm and Association Rules has been given, and this paper has presented an improved extract method of association rules of genetic algorithm based on their respective advantages and disadvantages. It also did some research on designing encoding methods, structuring and choosing fitness functions, and improving crossover operators and mutation operators. In the end, the analysis of contemporary youth consumption condition has been shown as a specific example to illustrate the process of mining association rules of contemporary youth's consumption behavior.
Moisture-induced failures of adhesive flip chip interconnects

Adhesive flip chip interconnect has been recognized as a promising substitute for solder interconnection due to its fine-pitch, lead-free, and low-temperature processing capabilities. As adhesives are made of polymers, moisture absorption by the polymeric resin remains as one of the principal contributors to adhesive joint failure mechanisms. In this research, the reliability performance of the adhesive flip chip in the pressure cooker test and moisture sensitivity test conditions was investigated. The failure modes were found to be interfacial delamination and bump/pad opening which may eventually lead to total loss of electrical contact. Different sizes of bump/pad opening in the interconnections were discussed in the context of the significance of mismatch in coefficient of moisture expansion (CME) between adhesive and other components in the package, which induces a hygroscopic swelling stress. The effect of moisture diffusion in the package and the CME mismatch were also evaluated from the standpoint of finite element modeling. In this study, it is concluded that hygroscopic swelling assisted by loss of adhesion strength upon moisture absorption is responsible for the moisture-induced failures in these adhesive flip chip interconnects.
Hierarchical Feature For Scene Parsing Using Fully Recurrent Network

In scene parsing, the wide-range contextual information is not effectively encoded. Scene parsing provides segmentation and determines an scene into different regions associated with semantic categories. The main objective of scene parsing is to reduce semantic gap between humans and computer machines on scene understanding. The scenes parsing applications are object detection, text detection on video frames etc. Scene parsing is one of the key problems in computer vision and solved using Recurrent neural network. Labeling small objects is the main difficulties in the scene parsing. The proposed method is Fully Recurrent Network using BiDirectional Recurrent neural network enables the network to model long-range semantic dependencies among image unit. Local representation and Local classification can be enhanced by Directed Acyclic Graph. Training RNN using gradient based method. Back propagation through time algorithm can be used to calculate the gradient method. Recognition accuracy can be improved with the class weighting function.The result can be predicted accuracy using Siftflow data set.
Cathodoluminescence in transmission electron microscopy

We describe a cathodoluminescence spectrometer that is attached to an analytical transmission electron microscope. After a brief consideration of the set‐up and the peculiarities of recording spectra and of mapping defect distributions in panchromatic and monochromatic cathodoluminescence, we discuss two examples of applications. Emphasis is placed on the potential for obtaining novel information about materials and processes on a microscopic and a nanoscopic scale by combining cathodoluminescence with the structural and chemical information for the same site of the specimen. We select an example concerning the role of In distribution in light emission from InGa/GaN quantum wells and a second one concerning the analysis of the initial electron radiation damage of Cu(In,Ga)Se2 photovoltaic films.
A rough set-based association rule approach implemented on a brand trust evaluation model

Abstract In commerce, businesses use branding to differentiate their product and service offerings from those of their competitors. The brand incorporates a set of product or service features that are associated with that particular brand name and identifies the product/service segmentation in the market. This study proposes a new data mining approach, a rough set-based association rule induction, implemented on a brand trust evaluation model. In addition, it presents as one way to deal with data uncertainty to analyse ratio scale data, while creating predictive if–then rules that generalise data values to the retail region. As such, this study uses the analysis of algorithms to find alcoholic beverages brand trust recall. Finally, discussions and conclusion are presented for further managerial implications.
The Influence of Anti–tumor Necrosis Factor Agents on Hemoglobin Levels of Patients with Inflammatory Bowel Disease

Background:Anti–tumor necrosis factor (TNF) agents are an important component of inflammatory bowel disease (IBD) treatment, but data on their influence on anemia, a frequent complication of IBD, are limited. The aim of this study was to evaluate the effect of anti-TNF agents on hemoglobin (Hb) levels in a large IBD cohort. Methods:Prospectively collected demographic, clinical, laboratory, and treatment data from IBD patients who started anti-TNF treatment at a tertiary referral center during the years 2010 to 2012 were analyzed. Follow-up data including disease activity scores (Harvey–Bradshaw index or ulcerative colitis activity index), quality of life scores (short IBD questionnaire) completed at each visit, and laboratory data were analyzed. Data from the year of anti-TNF initiation (yr 0) to the following year (yr 1) were compared. Results:A total of 430 IBD patients (324 with Crohn's disease, 51.6% females) started anti-TNF treatment. The prevalence of anemia and median Hb levels did not change between years 0 and 1. Median short IBD questionnaire was significantly improved at year 1 (P = 0.002). IBD patients with anemia had significantly higher median Hb levels at year 1 compared with year 0 (P = 0.0009). Hematopoietic response (increase of Hb ≥2 g/dL) was observed in only 33.6% of the 134 anemic IBD patients, despite iron replacement being administered in 126 anemic patients (oral, 77%). Improvement in Hb levels was independently significantly correlated with change of C-reactive protein levels (P = 0.04) and immunomodulator use (P = 0.03). Conclusions:Anemia remains a significant manifestation of IBD 1 year after treatment with anti-TNF agents.
An unconventional VNA-based time-domain waveform load-pull test bench

In this paper we describe an unconventional technique that simplifies time-domain waveform measurements of non-linear devices under large signal conditions. The implemented system is based on a commercial vector network analyzer and on a sampling oscilloscope, instrumentation that can be commonly found in any industrial or research microwave laboratory. Unlike other measurement systems commercially available, or presented in technical papers and reports, this test-set does not need any comb generator, neither for calibration, nor for measurements. To the author's knowledge, this is the first time a low-cost system with these unique characteristics is presented.
The differentiation of herpes simplex virus type 1 and type 2 by temperature markers.

Herpes simplex viruses have been divided into two types. These types may be differentiated by serological tests (Shubladze et al. 1960; Plummer, Waner & Bowling, 1968) and by the character of the lesions produced on the chorioallantoic membrane (CAM) of fertile hens' eggs (Parker & Banatvala, 1967) and in tissue culture (Lowry, Melnick & Rawls, 1971). It has been suggested recently that the serological classification into type 1 and type 2 may be too rigid and that a whole spectrum of variants may exist (Roizman et al. 1970). The two types have a characteristic biological differentiation, type 1 being associated mainly with lesions of the face and type 2 with lesions of the genital tract. The observation that genital strains may be linked in some way with carcinoma of the cervix (Naib, 1966) has increased interest in these viruses. Growth at different temperatures has proved a useful marker for several groups of viruses.