Miracle-dz/UniFAR-FTUs huggingface dataset:
Sporting programs for inactive population groups

Background: The organized sports sector has received increased attention as a setting to promote health-enhancing physical activity (HEPA) to the general population. For significant public health impact, it is important that successful HEPA programs are widely adopted, implemented and continued as ongoing practice. The importance of evaluating the context in which programs are implemented has been identified as critical. However, little research has focused on understanding the organized sports implementation context, including factors facilitating and impeding implementation. In this study, the main factors influencing implementation of HEPA programs in the organized sports setting were studied. Methods: Fourteen sporting programs in the Netherlands aimed at increasing participation in sports by inactive population groups and funded within the National Action Plan for Sport and Exercise (NAPSE) were investigated. The programs were developed by ten Dutch National Sports Federations (NSFs) and implemented by different sports clubs in the Netherlands over a 3-year implementation period (June 2008 – June 2011). The qualitative research component involved yearly face-to-face interviews (i.e. fourteen interviews each year, n = 12 program coordinators) and a group meeting with the program coordinators of the NSFs ( n = 8). Cross-case comparisons and thematic analyses were performed to identify and categorize important facilitating and impeding factors respectively. The quantitative research component, used to identify the most important facilitating and impeding factors across all sporting programs, consisted of ranking of factors according to importance by the program coordinators ( n = 12). Results: Different factors act during six identified (implementation) phases. When comparing factors across phases, several key learnings were evident. Successful implementation relied, for example, on program design and enthusiastic individuals within sporting organizations. On the other hand, inactive people were hard to reach and participation of sports clubs was not self-evident. The findings were discussed in a broader context. Conclusions: This study adds to the knowledge base concerning the implementation of sporting programs, aimed at inactive people, in the organized sports setting. The main factors facilitating and impeding implementation were identified. The results of this study can be used by sports practitioners and policy makers when developing and implementing HEPA programs in this setting.
THE INFLUENCE OF HIGH-PERFORMANCE WORK SYSTEM (HPWS) ON THE INDIVIDUAL PERFORMANCE OF BONDARY SPANNERS WITHIN TRADED COMPANIES IN MOROCC0 PERFORMANCE (HPWS)

de comparer leurs avec celles des : Système de travail à haute performance (HPWS), autonomie, récompenses, performance individuelle, personnel contact, cotées ABSTRACT The objective of this article is to highlight the High-Performance Work System (HPWS), made up of HR practices and how it affects the individual performance of bondary spanners in traded companies in Morocco. The aim is therefore to empirically analyze this relationship through a questionnaire that was administered to 76 employees who work with customers or suppliers of traded companies. The results revealed that the training of Bondary spanners positively influences their performance, whereas empowerement and rewards have no influence on their performance. The implications resulting from this research have also been suggested with the aim of combining a large number of factors in order to successfully implement these practices in different environments. As for future research perspectives, it would be very interesting to look at different categories of employees and compare their perceptions with those of managers.
publications Genome wide SNP identification in chickpea for use in development of a high density genetic map and improvement of chickpea reference

Background: In the whole genome sequencing, genetic map provides an essential framework for accurate and efficient genome assembly and validation. The main objectives of this study were to develop a high-density genetic map using RAD-Seq (Restriction-site Associated DNA Sequencing) genotyping-by-sequencing (RAD-Seq GBS) and Illumina GoldenGate assays, and to examine the alignment of the current map with the kabuli chickpea genome assembly. Results: Genic single nucleotide polymorphisms (SNPs) totaling 51,632 SNPs were identified by 454 transcriptome sequencing of Cicer arietinum and Cicer reticulatum genotypes. Subsequently, an Illumina GoldenGate assay for 1,536 SNPs was developed. A total of 1,519 SNPs were successfully assayed across 92 recombinant inbred lines (RILs), of which 761 SNPs were polymorphic between the two parents. In addition, the next generation sequencing (NGS)-based GBS was applied to the same population generating 29,464 high quality SNPs. These SNPs were clustered into 626 recombination bins based on common segregation patterns. Data from the two approaches were used for the construction of a genetic map using a population derived from an intraspecific cross. The map consisted of 1,336 SNPs including 604 RAD recombination bins and 732 SNPs from Illumina GoldenGate assay. The map covered 653 cM of the chickpea genome with an average distance between adjacent markers of 0.5 cM. To date, this is the most extensive genetic map of chickpea using an intraspecific population. The alignment of the map with the CDC Frontier genome assembly revealed an overall conserved marker order; however, a few local inconsistencies within the Cicer arietinum pseudochromosome 1 (Ca1), Ca5 and Ca8 were detected. The map enabled the alignment of 215 unplaced scaffolds from the CDC Frontier draft genome assembly. The alignment also revealed varying degrees of recombination rates and hotspots across the chickpea genome. Conclusions: A high-density genetic map using RAD-Seq GBS and Illumina GoldenGate assay was developed and aligned with the existing kabuli chickpea draft genome sequence. The analysis revealed an overall conserved marker order, although some localized inversions between draft genome assembly and the genetic map were detected. The current analysis provides an insight of the recombination rates and hotspots across the chickpea genome.
Regenerative Orthopedics

Mesenchymal stem cells (MSCs) are multipotent, adult stem cells that show clinical potential as therapeutic agents in regenerative medicine(Bruder et al., 1994; Barry, 2003; Alhadlaq & Mao, 2004; Gangji et al., 2005; Cha & Falanga, 2007). They are also known as marrow stromal cells and are derived from mesodermal tissues. The clonal nature of a subpopulation of marrow nucleated cells was discovered in the 1960’s (Becker et al., 1963). These cells were later assayed and renamed “colony forming fibroblasts”(Friedenstein et al., 1974). Experiments through the 1980’s and 1990’s demonstrated that environmental clues assisted MSCs in differentiating into different cell types. For example, culturing with ascorbic acid, inorganic phosphate, or dexamethasone could differentiate cells to osteoblasts, while culturing in the presence of TGF-beta caused cells to differentiate into chondrocytes (Alhadlaq & Mao, 2004). More recently it has been shown that bone marrow MSCs are actually a heterogeneous population of similar cells rather than one distinct cell type (Zhou et al., 2005). As a result, there is still no uniformly accepted definition of an MSC. Despite this issue, some groups have attempted to provide a definition which consists of adherence to plastic, MSC specific cell surface markers consistent with MSCs, as well as multi-lineage mesodermal tissue differentiation (Schauwer et al., 2010).
Fan‐shaped antennas: Realization of wideband characteristics and generation of stop bands

This paper presents four fan‐shaped antennas: U.S.‐FAN, CROSS‐FAN, CROSS‐FAN‐W, and CROSS‐FAN‐S. Each of these antennas stands upright above a ground plane, and has edges expressed by an exponential function and a circle function. The four antennas are investigated using frequencies from 1.5 GHz to 11 GHz. The CROSS‐FAN is found to have a lower VSWR over a wide frequency band compared to the U.S.‐FAN. The CROSS‐FAN‐W and CROSS‐FAN‐S are modified versions of the CROSS‐FAN, each designed to have a stop band (a high VSWR frequency range) for interference cancellation. The stop band for the CROSS‐FAN‐W is controlled by a wire (total length 4Lwire) that connects the fan‐shaped elements. The center frequency of the stop band fstop is close to the frequency corresponding to a wire segment length Lwire of half the wavelength. It is also found that the stop band in the CROSS‐FAN‐S can be controlled by four slots, one cut into each of the fan‐shaped elements. The center frequency of the stop band fstop is close to the frequency corresponding to a slot length Lslot of one‐quarter of the wavelength. Experimental work is performed to confirm the theoretical results, using the CROSS‐FAN‐S.
Computation of Reflection Coefficients for Layered Media*

A fast computer program of the Thomson-Haskell matrix formalism is presented for the computation of the P- SV reflection coefficients RPP' Rps' Rss and Rsp for layered solid media. A matrix formalism and a computer program are also derived for the computation of P reflection coefficients for layered liquid media and of SH reflection coefficients for layered solid media. for of A computer program for for layered
Confirming the Frame-Dragging Effect with Satellite Laser Ranging

The theory of General Relativity predicts several non-Newtonian effects that have been observed by experiment, but one that has proven to be challenging to directly confirm is the so-called frame dragging‘ effect. One manifestation of this effect is the Lense-Thirring precession of a satellite‘s orbital plane due to the Earth‘s rotation. While the signal is large enough to be easily observed with satellite laser ranging, the Lense-Thirring measurement uncertainty is limited by the knowledge of the even zonal harmonics of the Earth‘s gravity field that also produce Newtonian secular orbit precessions. In the late 1980‘s, it was proposed to launch the LAGEOS-3 satellite matching LAGEOS-1, except that the orbit inclination would be exactly supplementary to LAGEOS-1. This would have allowed the cancellation of the equal but opposite orbit precession due to the Earth‘s gravity field to reveal the Lense-Thirring precession. However, this satellite was never launched, and the orbit selected for LAGEOS-2 was not sufficiently close to the proposed LAGEOS-3 orbit specifications to support an accurate Lense-Thirring experiment with the available gravity models. However, this problem has been largely overcome with the dramatically improved models resulting from the joint NASA-DLR Gravity Recovery and Climate Experiment (GRACE) mission. Using laser ranging to LAGEOS-1 and LAGEOS-2, we demonstrate, with an error analysis based on several now-available GRACE gravity models, that the General Relativity prediction of the Lense-Thirring precession can be confirmed with an uncertainty better than 15%, in good agreement with previously published results. In addition, with extensive modeling improvements in the various models, including the terrestrial reference frame and solid earth and ocean tides, we show that a credible experiment can be conducted with just four years of SLR overlapping the GRACE mission.
methylation and RNAi pathways regulate normal nucleolar and repeated DNA organization by inhibiting formation of extrachromosomal DNAs

In order to identify regulators of nuclear organization, Drosophila mutants in the Su(var)3-9 histone H3K9 methyltransferase, RNAi pathway components, and other regulators of heterochromatin-mediated gene silencing were examined for altered nucleoli and positioning of repeated DNAs. Animals lacking components of the H3K9 methylation and RNAi pathways contained disorganized nucleoli, ribosomal DNA (rDNA) and satellite DNAs. The levels of H3K9 dimethylation (H3K9me2) in chromatin associated with repeated DNAs decreased dramatically in Su(var)3-9 and dcr-2 ( dicer-2 ) mutant tissues compared to wild type. We also observed a substantial increase in extrachromosomal repeated DNAs in mutant tissues. The disorganized nucleolus phenotype depends on the presence of Ligase 4 ( Lig4 ), and ecc DNA formation is not induced by removal of cohesin. We conclude that H3K9 methylation of rDNA and satellites, maintained by Su(var)3-9, HP1, and the RNAi pathway, is necessary for the structural stability of repeated DNAs, which is mediated through suppression of non-homologous end joining (NHEJ). These results suggest a mechanism for how local chromatin structure can regulate genome stability, and the organization of chromosomal elements and nuclear organelles.
OXIDATIVE STRESS REACTIVE OXYGEN SPECIES AND ANTIOXIDANT DEFENSE SYSTEM IN PERIODONTITIS - A REVIEW

Periodontitis is an inflammatory disease that results in the destruction of supporting periodontal tissues of the teeth, which is primarily initiated by bacterial infection and subsequently modified by anomalous (abnormal, aberrant) host response. As the oxidants and antioxidants are in dynamic equilibrium, any disturbance in one would lead to oxidative Stress. Whenever periodontitis occurs, reactive oxygen species are produced mostly by hyperactive neutrophils that could not be neutralized by antioxidant defense system, cause tissues damage. This tissues damage is mainly characterized by increased lipid peroxidation, DNA damage and protein damage leading to formation of oxidative stress markers. This article focuses on the reactive oxygen species, oxidative stress markers and antioxidant defense system in periodontitis.
An application of Multivariate Models on GSRTC Data

In this study a systematic methodology is developed to find out the causes & effects of the variability which helps to study the parameters of GSRTC so, various multiple regression analysis are developed. We have tried to find out the main parameters affects the margin of GSRTC. These variables provide the negative correlation with the rate of changes in the margins of the selected 16 depots of GSRTC, which shows that these variables also have negative linear relationships. By compressing these variables margin can be increase. Here, we have tried to show how space and time matters to the particular problem and how much important space statistics is? In connection with the research the data are adapted for the 16 major depots of GSRTC. We discussed about (1) Weighted Least Square Regression and Heteroskedastic Regression (2) Transformation of WLS Regression for GSRTC data sets of 2005 to 2016.
Running head: DIFFERENCES IN SUSCEPTIBILITY TO FRIEND DELINQUENCY 1 In Press: European Journal of Personality Longitudinal Associations Between Delinquent Behavior of Friends and Delinquent Behavior of Adolescents: Moderation by Adolescent Personality Traits

In this longitudinal study we examined whether personality traits (parent-rated Big Five personality traits) render some adolescents more susceptible than others to delinquent behavior of friends, predicting rank-order changes in adolescents’ self-reported delinquent behavior. We examine susceptibility to both perceived (reported by adolescents) and self-reported (reported by friends) delinquent behavior of friends. Participants in this two-wave study were 285 Dutch adolescents and their best friend. The adolescents (50% girls) were 15.5 years old on average ( SD = 0.8 years), and their best friends ( N = 176; 58% girls) were 15.1 years old ( SD = 1.5 years). Perceived (but not self-reported) delinquency of friends predicted a stronger increase in adolescent delinquency one year later, especially among adolescents low or average on conscientiousness. Emotional stability, agreeableness, extraversion, and openness did not moderate associations between delinquency of friends and delinquency of adolescents. Our findings show that low conscientiousness serves as a risk factor, increasing vulnerability to perceived delinquent behavior of friends, while high conscientiousness serves as protective factor, increasing resilience to perceived delinquent behavior of friends. Our findings also show that adolescents are susceptible to, and differ in susceptibility to, friends’ delinquent behavior as they perceive it —not to delinquent behavior as reported by friends themselves.
Lower Risk of Cancer in Patients on Metformin in ComparisonWith Those on Sulfonylurea Derivatives Results from a large population-based follow-up study

OBJECTIVEdNumerous studies have suggested a decreased risk of cancer in patients with diabetes on metformin. Because different comparison groups were used, the effect magnitude is difficult to estimate. Therefore, the objective of this study was to further analyze whether, and to what extent, use of metformin is associated with a decreased risk of cancer in a cohort of incident users of metformin compared with users of sulfonylurea derivatives.
RMHP_A_261221 1079..1093

*These authors contributed equally to this work Objective: The incidence of gynecological cancer is high in China, and the effects of related treatments and preventive measures need to be improved. Methods: This study uses GIS spatial analysis methods and a scanning statistical analysis to study the major gynecological cancers in northern Jiangxi Province from 2016 to 2018. Results: The incidence and spatial pattern of cervical cancer, ovarian cancer, and uterine cancer had agglomeration characteristics and changes during the study period. The gynecological cancer had a spatial autocorrelation and agglomeration in its spatial pattern. The Moran’s Index of the overall gynecological cancer incidence rate was 0.289 (p = 0.005). Ripley’s L(d) function showed that the agglomeration radius was between 51.40 and 52.82 km. The results of the kernel density estimation showed that the cases of gynecological cancer were concentrated in the central and northeastern areas of the study area. The overall county-level incidence of gynecological cancer varied from 0.26 to 11.14 per 100,000. The results of the gravity center analysis showed that the spatial distribution of the gravity center point of gynecological cancer had moved toward the east during the past three years. The results of a hotspot analysis showed that there were five hotspot areas that had gynecological cancers. The most likely clusters of gynecological cancer at the county level in northern Jiangxi Province were distributed in the adjacent areas of Jiujiang, Yichun, and Nanchang, with a relative risk of 1.85. Conclusion: The research shows that GIS can display the distribution of cancer cases and can use spatial analysis methods and scanning statistical techniques to obtain key areas of cancer incidence. These results can provide data and key areas for the formulation of regional public health policies and provide recommendations for cancer screening and the rational allocation of health resources.
HSOA Journal of Plant Science: Current Research Research Performance of Wheat Genotypes under Cadmium Contamination of Soil

pot having 375g of soil using the electric balance. Completely Randomized Design (CRD) was used with four replications at different levels of cadmium concentrations (control, 5 ppm, 10 ppm, 15 ppm, 20 ppm, and 25 ppm). Parameters recorded in this study were germination percentage, plant height, fresh shoot weight, and dry shoot weight and cadmium contents in shoot. Germination percentage was taken after 30 days of sowing by dividing total number of seedling emerged over the Abstract In order to evaluate different wheat genotypes against cadmium contamination of soil, an experiment was carried out in the department of Plant Breeding and Genetics, Pir Mehr Ali Shah-Arid Agri- culture University Rawalpindi. The experiment was carried out under the control conditions. The experiment was laid out by using two factorial Completely Randomized Design (CRD) with six treatments and four replications. The treatments included six cadmium concen- trations of cadmium in soil i.e., (control treatment, 5 ppm, 10 ppm, 15 ppm, 20 ppm and 25 ppm). Parameters studied were germination % age, plant height (cm), fresh shoot weight (g), dry shoot weight (g) and cadmium contents in shoot. The results showed the accumula- tion of cadmium in shoot of different wheat genotypes as compared to control treatment. Cadmium depicted the great variation as com- pared to control in different parameters studied.
Http Streaming Based Ajax Player

: In the previous couple of years streaming of video on the web has encountered quick development and will keep on expanding in significance as broadband innovations and authoring tools keep on making strides. As the internet turns into an inexorably famous alternative to traditional communications media, internet streaming will turn into a critical segment of numerous content providers’ communications strategy. In this paper we proposed a solution to HTTP live streaming, which assesses the weights of media segments to choose the transmitting needs taking into account the present playing time and alter the proper transmission path.
Role of Transcription Factor Kar4 in Regulating Downstream Events in the Saccharomyces cerevisiae Pheromone Response Pathway (cid:1)

Yeast Kar4 is a putative transcription factor required for karyogamy (the fusion of haploid nuclei during mating) and possibly other functions. Previously known to be required only for the transcriptional induction of KAR3 and CIK1 , microarray experiments identiﬁed many genes regulated by Kar4 in both mating and mitosis. Several gene clusters are positively or negatively regulated by mating pheromone in a Kar4-dependent manner. Chromatin immunoprecipitation and gel shift assays conﬁrmed that Kar4 binds to regulatory DNA sequences upstream of KAR3 . Together with one-hybrid experiments, these data support a model in which both Kar4 and Ste12 bind jointly to the KAR3 promoter. Analysis of the upstream regions of Kar4-induced genes identiﬁed a DNA sequence motif that may be a binding site for Kar4. Mutation within the motif upstream of KAR3 eliminated pheromone induction. Genes regulated by Kar4, on average, are delayed in their temporal expression and exhibit a more stringent dose response to pheromone. Furthermore, the induction of Kar4 by pheromone is necessary for the delayed temporal induction of KAR3 and PRM2 , genes required for efﬁcient nuclear fusion during mating. Accordingly, we propose that Kar4 plays a critical role in the choreography of the mating response. , by pheromone were selected for analysis. The data for the timing of induction in a bar1 (cid:5) strain for these genes (0, 15, 30, 45, and 60 min after induction) by 50 nM pheromone were obtained from previously published data (39). Similarly, data for the dose re- sponse of a bar1 (cid:5) strain to alpha factor exposure (0.15, 0.5, 1.5, 5, 15.8, 50, and 158 nM pheromone) after 30 min were previously published (39). A Stineman function was ﬁt to all datum points to obtain a local smoothing (KaleidaGraph 4.01; Synergy Software). The datum points corresponding to the half-maximal value ( t 1/2 ) were interpolated, and the t 1/2 for each gene was obtained. The statistical signiﬁcance was tested by using a heteroscedastic Student t test.