Miracle-dz/UniFAR-FTUs huggingface dataset:
On the principal series of _{} over-adic fields

The entire principal series of G = Gl (F), for a p-adic field F, is analyzed after the manner of the analysis of Bruhat and Satake for the spherical principal series. If K is the group of integral matrices in Gl (F), then a "principal series" of representations of K is defined. It is shown that precisely one of these occurs, and only once, in a given principal series representation of G. Further, the spherical function algebras attached to these representations of K are all shown to be abelian, and their explicit spectral decomposition is accomplished using the principal series of G. Computation of the Plancherel measure is reduced to MacDonald's computation for the spherical principal series, as is computation of the spherical functions themselves. Here we seek to illustrate, in the simplest case, the principal series of Gl , some facts which should be general features of harmonic analysis on semisimple p-adic groups; that is, they should hold to a large extent both for other series of representations of Gl , and for other semisimple groups. The main point I wish to clarify is the relation between harmonic analysis on Gl itself and on certain compact subgroups. We will begin with a review of the construction and basic facts of irreducibility and equivalence of the principal series. Then we will define the principal series for the standard maximal compact subgroup, and show the relation between the two by the study of the associated algebras of spherical functions. We will need notation. Let F be a p-adic field, R its ring of integers, n a prime element. Let F = R/nR be the residue class field, of order q = pa. Write G = Gl (F). B is the Borel subgroup of upper triangular matrices, N the group of unipotent upper triangular matrices, A the diagonal matrices, W the Weyl group of permutation matrices, P any parabolic subgroup containing B, Np the unipotent radical of P, Np the opposite group to Np, and Mp the standard (block diagonal) levi component of P. Received by the editors February 14, 1972. AMS (MOS) subject classifications (1970). Primary 22E50.
Competition between Superconductivity and Charge Density Waves: the Role of Disorder

More recently STM experimets present firm evidence of some kind of charge modulation in underdoped cuprates. The peculiar observations of the above experiments are located in the so called pseudo-gap region of the phase diagram, just over the superconducting-dome. The model that will be used captures in a simple way the idea that the pseudo-gap phase is formed of bound fermion pairs which are close to a CDW instability but generally do not have long range order due to quenched disorder. Thus the charge degrees of freedom will be modeled by an Ising order parameter in the presence of quenched disorder, so representing a charge glassy phase. This glassy phase will be in competition with a superconducting phase modeled by a complex order parameter. As a first step we will study the model in one dimension without disorder to familiarize with it and also to search for a possible explanation of the Giant Proximity Effect (GPE). After that we will investigate numerically the ground state properties of the 2-dimensional lattice model, focusing our attention especially on the stiffness and magnetization of the system in the xy plane. We will show that disorder can induce superconductivity in a CDW phase. This picture is really interesting because it could show how an insulating system can produce a superconducting phase thank to the interplay with impurites.
The Steep Spectrum Pulsar Population

We have sampled the population of compact (8 < 25") ra dio sources with spectral indices 1.5 < a < 3.2 (where S v oc v~ a ) using two large scale radio surveys. This yields a statistically useful sample of 74 radio sources with 51.4GHz > 2.5 mJy and S365MHZ > 200 mjy. The majority of the sources appear to be extragalactic, resembling either high redshift radio galaxies or relic radio galaxies. However, six known pul sars were detected, as well as 16 sources of unknown nature that appear too small and have spectra too steep to be extragalactic. We are using VLBA, pulsar searching, optical/IR spectroscopy, and other techniques to definitively classify these sources.
Tuning of terahertz metamaterials’ resonances via near field coupling

Electromagnetic metamaterials (MMs) consisting of highly conducting sub-wavelength metallic resonators enable many unusual electromagnetic properties at designed frequencies which are not permissible with the naturally occurring materials. The electromagnetic properties of metamaterial are typically controlled by the clever design of the MM unit cell, often termed as meta-molecule, consisting of metallic split ring resonators (SRRs) or meta-atoms. The near field coupling between meta-atoms plays a vital role in tuning the natural resonances of individual SRR and, therefore, has the ability to modify the far-field radiation properties significantly. It is shown that near field coupling between the meta-atoms could lead to resonance tuning, mode splitting, and ultrafast switching in passive and active resonators. In this article, we present a brief review on tuning the metamaterial properties by active and passive manipulation of near field coupling between neighboring split ring resonators.
Association between cost-sharing and drug prescribing in Korean elderly veterans with chronic diseases: A real-world claims data study

This study aimed to investigate the relationship between cost-sharing and drug prescribing and its appropriateness in Korean elderly veterans with chronic conditions. This is a cross-sectional study using real-world claims data. Veterans with primary hypertension or dyslipidemia were compared with two controls with higher levels of cost-sharing. Study subjects (age ≥65 years) were selected through stratified random sampling and matching the individual attributes. The primary outcome was the annual amount of drugs prescribed per patient, and the secondary outcomes included several other measures investigating multifaceted aspects of drug prescribing, medical institution utilization behavior, and prescribing appropriateness. Gamma regression models or logistic regression models were employed. Veterans were prescribed 59%~74% more drugs (exp (β) = 1.59 [95% confidence interval [CI] = 1.55–1.64] ~ 1.74 [1.70–1.79]) compared to the National Health Insurance (NHI) patients. This was attributed mainly to longer prescribing days (44%) and slightly more prescriptions (6%~7%) than NHI patients. Veterans spent 14%~15% higher medication costs. Veterans were less likely to visit multiple medical institutions by estimates of 0.77 (0.76–0.79) ~ 0.80 (0.79–0.82). Similar but smaller differences were observed between veterans and medical aid (MedAid) patients. The veteran patients showed a more than 50% increased risk of therapeutic duplication than the other two controls (adjusted odds ratio [ORs] = 1.47 [1.37–1.57] ~ 1.61 [1.50–1.72]). Inappropriate drug prescribing was also more common in veterans than the two controls (adjusted ORs = 1.20 [1.11–1.31] ~ 1.32 [1.22–1.43]). In Korean elderly veterans with chronic illnesses, a level of cost-sharing was associated with having more prescribed medicines, and increased inappropriate prescribing.
Prospective comparative study between knee alignment-oriented static and dynamic balance exercise in patellofemoral pain syndrome patients with dynamic knee valgus

Exercise therapy has been reported as an effective treatment method for patellofemoral pain syndrome (PFPS). However, there is a lack of studies regarding the effectiveness of balance exercise in the treatment of patients with PFPS. This study aimed to prospectively compare changes in proprioception, neuromuscular control, knee muscle strength, and patient-reported outcomes between patients with PFPS treated with knee alignment-oriented static balance exercise (SBE) and dynamic balance exercise (DBE). The participants were divided into 2 groups: 17 knee alignment-oriented SBE group and 19 knee alignment-oriented DBE group. Proprioception was assessed by dynamic postural stability using postural stabilometry. Neuromuscular control and knee muscle strength were measured for acceleration time and peak torque in quadriceps muscle using an isokinetic device. Patient-reported outcomes were evaluated using a visual analog scale for pain and the Kujala Anterior Knee Pain Scale. There was greater improvement in dynamic postural stability (0.9 ± 0.3 vs 1.2 ± 0.5; 95% confidence interval [CI]: 0, 0.6; Effect size: 0.72; P = .021) and quadriceps AT (40.5 ± 14.3 vs 54.1 ± 16.9; 95% CI: 2.9, 24.2; Effect size: 0.86; P = .014) in the DBE group compared to the SBE group. Knee alignment-oriented DBE can be more effective in improving dynamic postural stability and quadriceps muscle reaction time compared with the knee alignment-oriented SBE in PFPS patients with dynamic knee valgus.
The Effects of Cognitive Behavioral Therapy with Biofeedback Therapy on the Quality of Life, Anxiety, Depression and Somatic Symptoms in Patients with Dyssynergic Defecation: A Randomized Controlled Trial

Background: Dyssynergic defecation (DD) is a major cause of chronic functional constipation. Patients with DD have greater psychological distress and impaired health-related quality of life compared with the general population. This study aimed to evaluate the effectiveness of cognitive-behavioral therapy (CBT) combined with biofeedback therapy (BFT) on the quality of life, anxiety, depression and physical symptoms in patients with DD. Methods: This randomized controlled trial (IRCT20141115019957N2) was conducted on 45DD patients who were referred to the Rehabilitation Clinic of Iran University of Medical Sciences in 2017. The convenience sampling method was used to select the participants and then they were randomly allocated into three equal groups using RANDBETWEEN function in Excel. The first group received a combination of BFT&CBT and also standard-of-care therapy (SoCT). The second group was treated with BFT and SoCT, and the third group received only SoCT. The patients were assessed by digital rectal examination and the Short Form-36, Spielberger Anxiety, Beck Depression and Constipation Scoring System questionnaires before and after the treatment.The data were analyzed by SPSS-22, ANOVA, ANCOVA and Chi-Square tests. Results: Patients who received both CBT&BFT had significant improvement in symptoms of constipation, depression, and anxiety.Furthermore, BFT and CBT&BFT groups are valued equivalent only on the mental component of SF36 and the total SF36 questionnaire. But the physical component was significantly different, favoring CBT&BFT (p< 0.001). In CBT&BFT group,67%of patients reached the relaxed stage. In contrast, no patient reached the relaxed neither in BFT nor in SoCT. Conclusion: According to our study, patients with unfavorable responses to BFT may become better if CBT is added to their treatment plan.
Identification of signature of gene expression in biliary atresia using weighted gene co-expression network analysis

Biliary atresia (BA) is the most common cause of obstructive jaundice during the neonatal period. This study aimed to identify gene expression signature in BA. The datasets were obtained from the Gene Expression Omnibus database. Weighted gene co-expression network analysis identified a critical module associated with BA, whereas Gene Ontology (GO) enrichment analysis and Kyoto Encyclopedia of Genes and Genomes pathway enrichment analysis revealed the functions of the essential modules. The high-connectivity genes in the most relevant module constructed protein–protein interaction networks via the string website and Cytoscape software. Hub genes screened by lasso regression consisted of a disease classification model using the randomforest method. Receiver operating characteristic curves were used to assess models’ sensitivity and specificity and the model was verified using the internal and external validation sets. Ten gene modules were constructed by WGCNA, of which the brown module had a strong positive correlation with BA, comprising 443 genes. Functional enrichment analysis revealed that module genes were mainly involved in biological processes, such as extracellular matrix organization, cell adhesion, inflammatory response, and the Notch pathway (P < .001), whereas these genes were involved in the metabolic pathways and cell adhesion molecules (P < .001). Thirty-nine high-connectivity genes in the brown module constructed protein-protein interaction networks. keratin 7 (KRT7) and C-X-C motif chemokine ligand 8 (CXCL8) were used to construct a diagnostic model that had an accuracy of 93.6% and the area under the receiver operating curves for the model was 0.93. The study provided insight into the signature of gene expression and possible pathogenesis of BA; furthermore, it identified that the combination of KRT7 and CXCL8 could be a potential diagnostic model for BA.
Genetic polymorphism of pleiotrophin is associated with pain experience in Japanese adults: Case-control study

Genetic factors play a role in individual differences in pain experience. Here, we performed a genome-wide association study (GWAS) to identify novel loci regulating pain processing. We conducted a 2-stage GWAS and the candidate single-nucleotide polymorphisms (SNPs) association study on pain experience using an exploratory cohort of patients with cancer pain. The confirmatory cohort comprised of participants from the general population with and without habitual use of analgesic medication. In the exploratory cohort, we evaluated pain intensity using a numerical rating scale, recorded daily opioid dosages, and calculated pain reduction rate. In the confirmatory cohort, pain experience was defined as habitual nonsteroidal anti-inflammatory drug usage. Using linear regression models, we identified candidate SNP in the exploratory samples, and tested the association between phenotype and experienced pain in the confirmatory samples. We found 1 novel SNP (rs11764598)—located on the gene encoding for pleiotrophin on chromosome 7—that passed the genome-wide suggestive significance at 20% false discovery rate (FDR) correction in the exploratory samples of patients with cancer pain (P = 1.31 × 10-7, FDR = 0.101). We confirmed its significant association with daily analgesic usage in the confirmatory cohort (P = .028), although the minor allele affected pain experience in an opposite manner. We identified a novel genetic variant associated with pain experience. Further studies are required to validate the role of pleiotrophin in pain processing.
Living liver donor hilar anatomical variations and impact of variant anatomy on transplant outcomes

Donor anatomy is an essential part of donor selection and operative planning in living donor liver transplantation. In this study, variations of hilar structures, and the effects of variant anatomy on donor and recipient outcomes were evaluated. Living donor liver transplantations in a single center between January 2013 and December 2020 were retrospectively reviewed. In total, 203 liver transplantations were analyzed. Type 1 arterial anatomy, type 1 portal vein anatomy and type 1 bile duct anatomy were observed in 144 (70.9%), 173 (85.2%), and 129 (63.5%) donors, respectively. Variant biliary anatomy was observed more frequent in donors with variant portal vein branching than in those with type 1 portal anatomy (60.0% vs 32.3%, P = .004). The overall survival rates calculated for each hilar structure were similar between recipients receiving grafts with type 1 anatomy and those receiving grafts with variant anatomy. When donors with variant anatomy and donors with type 1 anatomy were compared in terms of hilar structure, no significant difference was observed in the frequency of complications and the frequency of serious complications. Biliary variations are more common in individuals with variant portal vein anatomy. Donor anatomic variations are not risk factors for inferior results of recipient survival or donor morbidity.
The Relationship between Experiences Level and Clinical Decision-Making Skill in Midwifery Students: A Cross-Sectional Study

Background: Development and assessment of clinical decision-making skills are essential in midwifery education because of their role in mothers' and infants' safety. Therefore, the present study's primary objective was to evaluate the relationship between experience levels and clinical decision-making skills using the key features (KFs) examination. Methods: One hundred and two midwifery students in five different education levels participated in this cross-sectional study through convenient sampling. Twenty KFs questions were designed based on the principles of the KFs examination. The participants' information, including grade point average (GPA), theoretical and practical scores of the obstetrics course, were collected. KFs scores were compared according to students' training semester by one-way analysis of variance (ANOVA). Pearson correlation was conducted to explore the correlation between KFs scores and GPA as well as theoretical and practical scores. All statistical analyses were performed at a significance level of 0.05 (p≤0.05). We used five kinds of effect size calculators, which include mean difference (MD), standardized mean difference (cohend), partial Eta-squared, Cohenf, and partial omega-squared. Results: There was no correlation between KFs scores and the grade point average, theoretical exam scores, and practical exam scores. KFs scores linearly rose as the learners' level increased with a mean± SD score of 7.61±1.09 during the third semester compared to 11.55 ± 1.89 during the eighth semester (p=0.001). The effect size of this result was large (partial omega square=0.35, partial eta square=0.38 & cohen’s f=0.73). The largest SMD was related to the comparison of KFs scores between the eighth and third semester (MD=3.58, SMD=2.554 [CI 95%: 1.719-3.389], p-value═ 0.001), and the lowest was related to the comparison between the third and fourth semesters (MD=0.354, SMD= 0.2 [CI 95%: -0.421-0.821], p=0.987). Conclusion: Establishing proficiency in clinical decision-making skills is a linear process greatly enhanced by experience, clearly shown by the present study results. Using KFs examination and obtaining extensive evidence to its benefit can allow us to renegotiate proficiency evaluation methods for students in clinical fields. the education curriculum should focus more on identifying clinical KFs skills than merely teaching knowledge about disease processes.
Yang-Mills-Higgs theory for symplectic fibrations

Our aim in this work is to study a system of equations which generalises at the same time the vortex equations of Yang-Mills-Higgs theory and the holomorphicity equation in Gromov theory of pseudoholomorphic curves. We extend some results and definitions from both theories to a common setting. We introduce a functional generalising Yang-Mills-Higgs functional, whose minima coincide with the solutions to our equations. We prove a Hitchin-Kobayashi correspondence allowing to study the solutions of the equations in the Kaehler case. We give a structure of smooth manifold to the set of (gauge equivalence classes of) solutions to (a perturbation of) the equations (the so-called moduli space). We give a compactification of the moduli space, generalising Gromov's compactification of the moduli of holomorphic curves. Finally, we use the moduli space to define (under certain conditions) invariants of compact symplectic manifolds with a Hamiltonian almost free action of S^1. These invariants generalise Gromov-Witten invariants. This is the author's Ph.D. Thesis. A chapter of it is contained in the paper math.DG/9901076. After submitting his thesis in April 1999, the author knew that K. Cieliebak, A. R. Gaio and D. Salamon had also arrived (from a different point of view) at the same equations, and had developed a very similar programme (see math.SG/9909122).
Decisional needs of patients with recurrent high-grade glioma and their families

Abstract Background High-grade gliomas are aggressive and life-threatening brain tumors. At the time of recurrence, the patients and their families need to decide on future treatment. None of the treatment options are curative, and tradeoffs between benefits and harms must be made. This study aimed to explore the patients’ and family members’ decisional needs when making the decision. Methods We performed semi-structured individual interviews with patients and family members to explore their experiences during the decision making. A phenomenological hermeneutical analysis was conducted. Results A total of 15 patients and 14 family members aged 22-79 years participated in the study. Most of the family members were partners to the patient. The findings were centered around three interrelated and concurrently occurring themes: (I) A patient- and family-centered decision making, including the subtheme of being a supportive family member; (II) Balanced information and a trustful professional encounter; and (III) The value of hope. We found that both the patients and family members preferred to be involved in the decision making and that a trustful relationship with the surgeon, balanced and tailored information, and sufficient time to make the decision were essential. The experience of hope had a significant influence on patients’ decisions. Conclusion This study found that patient and family involvement, balanced information, and hope were the primary decisional needs of patients and family members at the time of recurrent high-grade glioma. Patients and family members can have different decisional needs, making individual needs assessment essential to decisional support.