Miracle-dz/UniFAR-FTUs huggingface dataset:
SYNTHESIS OF 3‐AMINO‐2,3,4,5‐TETRAHYDRO‐1‐BENZOXEPIN‐5‐OLS AND THEIR ACTION ON GASTRIC MOTILITY

Durch Kondensation R′- und Rz-substituierter 2,3,4,5-Tetrahydro-1-benzoxepin-3,5-dione mit R3- und R′-substituierten Aminen und anschlie- βende ein- oder zweistufige Reduktion der Kondensationsprodukte werden die Titelverbindungen (I), jeweils in cis- bzw. trans-Form getrennt, dargestellt.
Adaptive Granularity Based Last-Level Cache Prefetching Method with eDRAM Prefetch Buffer for Graph Processing Applications

The emergence of big data processing and machine learning has triggered the exponential growth of the working set sizes of applications. In addition, several modern applications are memory intensive with irregular memory access patterns. Therefore, we propose the concept of adaptive granularities to develop a prefetching methodology for analyzing memory access patterns based on a wider granularity concept that entails both cache lines and page granularity. The proposed prefetching module resides in the last-level cache (LLC) to handle the large working set of memory-intensive workloads. Additionally, to support memory access streams with variable intervals, we introduced an embedded-DRAM based LLC prefetch buffer that consists of three granularity-based prefetch engines and an access history table. By adaptively changing the granularity window for analyzing memory streams, the proposed model can swiftly and appropriately determine the stride of memory addresses to generate hidden delta chains from irregular memory access patterns. The proposed model achieves 18% and 15% improvements in terms of energy consumption and execution time compared to global history buffer and best offset prefetchers, respectively. In addition, our model reduced the total execution time and energy consumption by approximately 6% and 2.3%, compared to those of the Markov prefetcher and variable-length delta prefetcher.
Optimization of Machining Parameters in Blisk Processing Based on Tool Reliability

Machining parameters are essential factors affecting the machining efficiency and tool life. Tool reliability varies with the process. Tool reliability affects the life of the tool, and then impacts the processing quality and manufacturing cost. Therefore, machining parameters optimization considering tool reliability is essential and scientific. In this paper, firstly the reliability model of tool life was solved by Markov Chain Monte Carlo (MCMC) method. Then taking the average tool life as the constrain condition, a multi-objective optimization algorithm that integrates the gray correlation analysis (GRA), radial basis neural network(RBF) and particle swarm optimization(PSO) algorithm (GRA-RBF-PSO) was used to search for optimal machining parameters of blisk-tunnel processing. At last, experiments were carried out to validate optimized results. The experimental results indicated that the reliability-based optimization of machining parameters can effectively improve the tool life and as well as ensure smaller cutting force and larger material removal rate during blisk-tunnel processing.
A prospective observational study of the maternal and neonatal outcome of COVID positive deliveries in a tertiary care institution in Chennai

Background: Pregnancy alters the body’s immune system and response to viral infections in general, which can occasionally cause more severe symptoms. This may be the same for COVID-19 but there is currently no evidence that pregnant women are more likely to need admission to intensive care or have increased morbidity and mortality than non-pregnant adults. This study was undertaken at Govt RSRM Lying in Hospital, Royapuram, and Chennai which is a tertiary care institution and referral centre for all COVID positive antenatal patients from the surrounding Containment areas. Aim of the study: To study the maternal and neonatal outcome of COVID positive antenatal patients admitted in GOVT RSRM Lying in Hospital. Methodology: All patients who delivered in the COVID ward of our hospital have been observed and their maternal and neonatal outcome and recovery was documented. Study Period: From April 2020 to July 2020 Results: 741 patients were admitted in the COVID ward of our hospital from April to July 2020. Totally 301 patients delivered during this period with 151 LSCS, 138 Labournaturale and 12 Outlet forceps deliveries. 76.4% of the patients belonged to the age group of 21 to 30 years. 57 patients were primigravida and 244 patients were multigravida patients.97. 3% of the patients were asymptomatic and were detected as COVID Positive in routine antenatal screening or contact tracing.93. 4% of the patients admitted in COVID ward were from the major containment areas of Chennai like Tondiarpet and Royapuram. The COVID positive patients had obstetric complications like GHTN, GDM and also other comorbidities. Conclusion: All antenatal patients nearing delivery are now being universally screened for COVID 19 infection and isolation and contact tracing is being done. Public health measure like Social distancing, hand washing, avoiding crowded areas and wearing protective face masks will go a long way in the control of the pandemic.
Development and Psychometric Evaluation of the Female Substance Abusers’ Reproductive Health Scale: Study Protocol for a Sequential Exploratory Mixed-method Study

Aims: This study aims at the development and psychometric evaluation of the Female Substance Abusers’ Reproductive Health Scale (FSARHS). Design, Setting and Participants: This is the protocol of a sequential exploratory mixed-method study. The study will be conducted in an FSARHS development phase and an FSARHS psychometric evaluation phase. In the first phase, a qualitative study and a literature review will be conducted for item generation. In the qualitative study, semi-structured interviews will be held with female substance abusers. Data will be analyzed through conventional content analysis and the draft of FSARHS will be developed. In the psychometric evaluation phase, the face, content, and construct validity and reliability of FSARHS will be assessed. Conclusions: FSARHS can be used by reproductive health policy makers and health care providers at national and international levels in order to assess reproductive health among female substance abusers.
A Scale Development Study Intended for Mathematics Teacher Candidates: Mathematical Visualization Perception Scale

The aim of this study is to develop a valid and reliable measurement tool that measures mathematical visualization perceptions for mathematics teacher candidates. Therefore, the type of study is a survey research. Research was carried out with 462 (336 Female, 125 Male) mathematics teacher candidates from a university located in the Eastern Anatolia region Turkey in 2018-2019 spring season. Exploratory and confirmatory factor analyzes were performed for the analysis of research data. In the process of development of Mathematical Visualization Perception Scale (MVPS); the preparation of the pool of material, testing of the validity of the scope and appearance, conducting the trial application, ensuring the construction validity, calculating the reliability and establishing the final scale were followed. As a result of the exploratory factor analysis, a valid and reliable 5-point Likert-type scale consisting of 42 items, with 6 factors [Additional Drawing (AD), Spatial Thinking (ST), Direction Concept (DC), Relation with Daily Life (RDL), Transition from Algebra to Geometry (TAG) and Transition from Geometry to Algebra (TGA)] was created. Cronbach Alpha internal stability coefficient of these factors was calculated as 0.938. The factor structure of the scale was also confirmed by confirmatory factor analysis. As a result of the findings obtained, it was suggested to the researchers who will study in the related field to evaluate mathematical visualization perceptions of mathematics teacher candidates by using related scale with different sample groups or different variables.
Clinical Outcomes and Donor Site Morbidity of Anterior Cruciate Ligament Reconstruction with Full Thickness Peroneus Longus Tendon

Backgroud: Anterior cruciate ligament (ACL) is an important anatomical structure for maintaining the stability and moveability of a knee joint. When the load exceeds its strength, ACL will be damaged or broken. The main therapy for a fractured ACL is the arthroscopic ligament reconstruction technique. Commonly used reconstruction materials are grouped into three categories: autologous tendons, allogeneic tendons and artificial materials. Peroneal longus tendon(PLT) is an autograft, its superficial location and easier access contribute to its increasing application as a new graft substitute in cruciate ligament reconstructions over recent years. Our research is aiming to investigate the functional recovery of the knee joint after anterior cruciate ligament transplantation with autologous peroneus longus tendon under arthroscopy and its influence on the ankle joint of the donor site.Methods: During the research period of our retrospective analysis from January 2015 to July 2019, the single-bundle double-stranded anatomical reconstruction technique was applied under arthroscopy on 32 patients with acute anterior cruciate ligament ruptures (consisting of 22 males and 10 females in the 16–45 (31.1 ± 8.6) age bracket, and among them, 18 cases suffered knee injury on the left limb and the other 14 on the right one) within three weeks of their injury, and the graft for the anterior cruciate ligament (fixed with an Endobutton plate on one end and a screw on the other) was the autologous peroneus longus tendon on the ipsilateral limb. The IKDC score, KOOS score and Lysholm score were used to evaluate the functionality of the affected knee joints and the AOFAS score that of the tendons and ankle joints.Results: All patients were followed up for 1 year (14.5 ± 1.6 months). One case developed postoperative knee joint infection but recovered soon following active treatments, and all the patients turned negative in the postoperative Lachman tests and pivot-shift tests. At the last follow-up, IKDC score, KOOS symptom score, KOOS pain score, KOOS functional life score, KOOS sports entertainment score, KOOS life quality score and Lysholm score were 82.1 ± 13.5, 90.8 ± 15.5, 90.4 ± 5.9, 97.8 ± 4.3, 73.7 ± 26, 83.9 ± 18.1 and 87.3 ± 12.0, respectively, showing marked improvements on and statistically significant differences (P < 0.05) from the preoperative figures. The AOFAS score of the affected ankle joints was 94.7 ± 10.8, signifying a good functional recovery. MRI observation one year later showed that the reconstructed ligament had extended continuously to the position satisfying the requirements of anatomical reduction, and the bone tunnels and tendons had healed well.Conclusion: Reconstruction of the anterior cruciate ligament with a single-bundle of double-stranded peroneus longus tendon can satisfactorily restore the function of an injured knee joint without a significant impact on the donor ankle joint.
Using Multimedia Interactive in Online Learning in the Covid-19 Pandemic

—The Covid-19 outbreak has changed learning patterns that have been carried out by face-to-face methods with online learning. The purpose of this study was to find alternative learning methods implemented during the pandemic. The method used was a literature review. Online learning with computer-based interactive multimedia such as drills, tutorials, simulations, and games, can comply with health protocols. These learning methods can be used when the teacher and students are far apart, communication can be carried out effectively. The implication of this learning method is that students are increasingly creative, teachers are required to learn information technology. In addition, students are required to be independent, using various learning sources. The results of this study can be used for elementary school to senior high school education.
Abundances and morphotypes of the coccolithophore Emiliania huxleyi in southern Patagonia compared to neighboring oceans and northern-hemisphere fjords

Abstract. Coccolithophores are potentially affected by ongoing ocean acidification, where rising CO2 lowers seawater pH and calcite saturation state (Ωcal). Southern Patagonian fjords and channels provide natural laboratories for studying these issues due to high variability in physical and chemical conditions. We surveyed coccolithophore assemblages in Patagonian fjords during late-spring 2015 and early-spring 2017. Surface Ωcal exhibited large variations driven mostly by freshwater inputs. High Ωcal conditions (max. 3.6) occurred in the Archipelago Madre de Dios. Ωcal ranged from 2.0–2.6 in the western Strait of Magellan, 1.5–2.2 in the Inner Channel, and was sub-saturating (0.5) in Skyring Sound. Emiliania huxleyi was the only coccolithophore widely distributed in Patagonian fjords (> 96 % of total coccolitophores), only disappearing in the Skyring Sound, a semi-closed mesohaline system. Correspondence analysis associated higher E. huxleyi biomasses with lower diatom biomasses. The highest E. huxleyi abundances in Patagonia were in the lower range of those reported in Norwegian fjords. Predominant morphotypes were distinct from those previously documented in nearby oceans but similar to those of Norwegian fjords. Moderate-calcified forms of E. huxleyi A morphotype were uniformly distributed throughout Patagonia fjords. The exceptional R/hyper-calcified coccoliths, associated with low Ωcal values in Chilean and Peruvian coastal upwellings, were a minor component associated with high Ωcal levels in Patagonia. Outlying mean index (OMI) niche analysis suggested that pH/Ωcal conditions explained most variation in the realized niches of E. huxleyi morphotypes. The moderate-calcified A morphotype exhibited the widest niche-breadth (generalist), while the R/hyper-calcified morphotype exhibited a more restricted realized niche (specialist). Nevertheless, when considering an expanded sampling domain, including nearby Southeast Pacific coastal and offshore waters, even the R/hyper-calcified morphotype exhibited a higher niche breadth than other closely phylogenetically-related coccolithophore species. The occurrence of E. huxleyi in naturally low pH/Ωcal environments indicates that its ecological response is plastic and capable of adaptation.
India‐Elan Bank‐East Antarctica Breakup, Crustal Architecture, and Margin Evolution: Results From Constrained Potential Field and Process‐Oriented Gravity Modeling of Conjugate Margin Segments

We present here the results of a seismically well‐constrained potential field modeling along with process‐oriented gravity modeling across the Eastern Continental Margin of India (ECMI) and its conjugate East Antarctica Continental Margin (EACM). The study revealed both along‐strike variations in crustal architecture and effective elastic thickness (Te), showing a locally asymmetric pattern. Crustal stretching factors (β) estimated at these margins range between 1.5 and 4.0 with slightly lower values varying over the narrow zone in the Cauvery basin‐western Enderby basin and relatively higher values in other margin segments. The models reveal typical magma‐poor margin characteristics in the Krishna‐Godavari (K‐G) and Cauvery basin segments of ECMI. The ocean‐continent transition (OCT) in the K‐G basin and its conjugate (central Enderby basin) indicates asymmetric rifting marked by the development of a detachment fault separating the combined India‐Elan Bank margin and the EACM. The higher β values and magmatic underplating at OCT in the Mahanadi basin segment of ECMI may be related to the post‐breakup magmatic emplacement associated with the proximal activity of the Kerguelen plume after the separation of Elan Bank from India by a ridge jump during M2/M0 (124–120 Ma). The pre‐rift reconstruction model through the palinspastic restoration of margins suggests that the central part of ECMI (16–20°) is the ideal pre‐rift location for the Elan bank.
Clinical Evaluation of Two Techniques for Narrow Alveolar Ridge Expansion: Clinical Study

Background: techniques have been established in order to simultaneously allow horizontal bone expansion along with implant placement in one surgical visit. Aim/Hypothesis: nique (ODT) and threaded expanders technique (TET). Methods: Twenty-eight implant implants were inserted in 11 patients. Implants were divided into two equal distinct groups acB). Alveolar ridge thickness was measured in two different stages (at the base line, after expansion and implant placement), and amount of alveolar ridge expansion in mm was calculated for each implant. Results: Both techniques were useful in achieving expansion, and all implants placed were successful. The amount of achieved exof expansion in threaded expanders group was 1.5 mm. Conclusions: with Densah bur drilling was superior to manual threaded expanders.
Betaine could help ameliorate transport associated water deprivation stress in broilers by reducing the expression of stress-related transcripts and modulating water channel activity

Abstract This study evaluated the effects of betaine and pre-slaughter transport of broilers on meat quality, blood parameters, selected water channels (AQP) and stress-related transcripts. Ross 308 broilers (n = 336) were housed in 56-floor pens with seven replicates per treatment. In a 4 × 2 design, broilers were either supplemented with betaine in the feed (0.2%), in drinking water (1 or 2 mL/L), or un-supplemented, and then were transported for 5-min or 4-h pre-slaughter. The results revealed that broilers transported for long-distance had elevated blood glucose pre-slaughter, and their breast meat was characterised with lower initial pH, higher ultimate pH, higher 0-h post-mortem temperature, and lower water holding capacity than those transported for short-distance. Moreover, there was a two-way interaction effect between betaine and transport on the expression of brain genes (Proopiomelanocortin, AQP1, AQP4), muscle glucocorticoid receptor (GR), hepatic AQP3 and AQP9 and intestinal AQP3. Long-distance transport upregulated the relative expression of the muscle AQP9 and downregulated the hepatic GR. Furthermore, betaine in the water at 2 mL upregulated the muscle AQP9 and hepatic GR. In conclusion, betaine could ameliorate the water-deprivation stress associated with transportation by reducing the expression of stress-related transcripts and modulate water channels without improving broiler meat quality. HIGHLIGHTS Long-distance transport of broilers is stressful, as evidenced by rising blood glucose, high temperature of fresh meat, and expression of stress-related transcripts. Betaine could ameliorate the water-deprivation stress associated with transport by reducing the expression of stress-related transcripts and modulating water channels.
Mitigation possibilities of concrete pavement degradation

Monolithic as well as precast Portland Cement Concrete pavement have shown a gradual increase in quantity and severity of defects and failures in recent years. Especially, the radical increase in the auto-destructive deterioration of the concrete structure, which is most often described as the expansion reaction, is alarming. The consequences may lead to extreme reduction of the lifetime of concrete on loaded or unloaded surface courses. The main causes are due to the combined effect of environmental effects (climate, chemical pollution), drainage of roads and the behaviour of the existing cement binders, provided that we do not reflect the modification of pavement structure layers. Only the impact of climate effects can be effectively reduced on the existing roads. The paper presents a summary of results obtained from the current portfolio of secondary concrete protection products. The testing was performed in terms of resistance to water infiltration and durability against the common effects of freeze/thaw and salt. The results show a dependence or independence according to the material basis when exposed to secondary protection products. Oils, silicate emulsions and a group with other material bases, so called other products, behave quite differently.
Review of Internet of Things in Different Sectors: Recent Advances, Technologies, and Challenges

: Human beings and their activities are now connected through Internet of Things (IoT) with the evolution of wireless communication technologies. IoT is becoming popular and its usage is immensely increasing among various sectors. In this research paper, a comprehensive review has been conducted by considering recent and important literature review on IoT applications being operated in three major sectors. The three sectors studied are health, sports and transportation and logistics. Paper explored that with the help of IoT techniques, different miniature sized devices are invented which can record various parameters of human body, wearables devices have been invented which are playing important role in monitoring and recording daily fitness are working on CIoT technology and IoT emergence in the field of transportation and logistics helps in resolving several issues including conveniences, navigation issues, service cost and security issues. All the papers reviewed are journal published from 2010 to 2020. In latter part, this paper also highlighted security, privacy, reliability, consumption of various resources and policies as significant challenges for IoT.
Single Sensor Based Global Maximum Power Point Tracking Algorithm of PV System With Partial Shading Condition

A current sensor based global maximum power point tracking (GMPPT) algorithm of photovoltaic system is proposed in this article to increase the tracking speed during partial shading condition. For the proposed algorithm, the tracking range of duty cycle is reduced by calculating both the upper limit and lower limit of duty cycle and skipping the duty cycle section without global maximum power point. Compared with maximum power trapezium (MPT) algorithm and the combination algorithm of MPT and search-skip-judge, the proposed algorithm reduces the tracking range of duty cycle during both tracking directions and only needs one current sensor to realize control. As a result, the proposed algorithm shows advantages of fast tracking speed, small energy loss, and low hardware cost. Followed by theoretical analysis, the simulation and experimental evaluation validate the claimed advantages of the proposed GMPPT algorithm.
Variations in Mid‐ to Late Holocene Nitrogen Supply to Northern Great Barrier Reef Halimeda Macroalgal Bioherms

The northern Great Barrier Reef (GBR) Halimeda bioherms have accumulated on the outer continental shelf from calcium carbonate algal sediments over the past ∼10,000 years and cover >6,000 km2 of shelf area. As such, Halimeda bioherms play a key role in the shallow marine carbon cycle over millennial timescales. The main source of nitrogen (N) to these bioherms is thought to be westward transport of upwelled NO3‐‐rich water from the Coral Sea. However, the primary N source has not been traced geochemically, and we have no understanding of any temporal variation. Here, we reconstruct patterns of N supply to Halimeda bioherms in the GBR since the mid‐Holocene using the 15N/14N ratio of skeletal‐bound organic N (δ15N‐skeletal organic material [SOM]) in modern and fossil Halimeda sediment cores. Average Halimeda skeletal δ15N‐SOM was 6.28 ± 0.26‰, consistent with δ15N‐NO3‐ from western tropical South Pacific (WTSP) thermocline waters. Thus, geochemically validating shelf‐break upwelling of an oceanic N source that regulates bioherm spatial distribution. Halimeda δ15N‐SOM decreased by 1‰–2‰ from 5,000 to 2,000 cal. yr BP, reaching a minima of 5.5‰ that persisted for almost 1,000 years. The Halimeda δ15N‐SOM variation reflects mid‐ to late Holocene changes in regional climate and intensified El Niño activity that likely facilitated elevated N2 fixation in the WTSP, thereby lowering thermocline δ15N‐NO3‐. Thus, Halimeda skeletal material provides a valuable high‐resolution geochemical archive of past oceanographic and climatic processes over centennial to millennial timescales, complementing existing paleoclimate proxy records.