Miracle-dz/UniFAR-FTUs huggingface dataset:
Detection of Mycoplasma agalactiae in Ticks (Rhipicephalus bursa) Collected by Sheep and Goats in Sicily (South-Italy), Endemic Area for Contagious Agalactia

The aim of this preliminary study was to investigate the presence of Mycoplasma agalactiae (Ma) or other Contagious Agalactia (CA) causative organisms, in hard ticks infesting milking sheep and goats in endemic areas for CA in Sicily (South-Italy). Although there is accumulating evidence to support the role of ticks in the transmission of blood-borne haemoplasmas, information regarding their role in the transmission of CA, remains scarce. Ticks (n = 152) were collected from 25 lactating sheep and goats from three farms with previous outbreaks of CA. Microbiological and biomolecular, as well as serological analysis were performed on milk, tick, and serum samples, respectively. Rhipicephalus bursa species predominated, comprising 84.8% of the sampled ticks. Mycoplasma-like colonies were isolated from 5/56 (8.9%) tick pools and were identified as Ma by specific PCR and 16S rRNA gene sequencing. Unexpectedly, the organism was isolated from R. bursa ticks recovered only from animals whose milk tested negative for the pathogen. This preliminary demonstration suggests the potential role for ticks to act as a reservoir for the organisms, with potential involvement in the spread and maintenance of CA. Further work is required to determine the location of the organisms within the body of the ticks and to assess transmission potential.
The Biological Effects of Ozone Gas on Soft and Hard Dental Tissues and the Impact on Human Gingival Fibroblasts and Gingival Keratinocytes

Ozone is an allotropic form of oxygen, so in the medical field ozone therapy has special effects. Starting from the premise that bio-oxidative ozone therapy reduces the number of bacteria, in the present study two approaches were proposed: to evaluate the biological effects of ozone gas on the tooth enamel remineralization process and to demonstrate its impact on the morphology and confluence of human primary gingival cells, namely keratinocytes (PGK) and fibroblasts (HGF). The ozone produced by HealOzone was applied in vivo to 68 M1s (first permanent molars), both maxillary and mandibular, on the occlusal surfaces at pit and fissure. The molars included in the study recorded values between 13 and 24 according to the DIAGNOdent Pen 2190 scale, this being the main inclusion/exclusion criterion for the investigated molars. Because the gas can make contact with primary gingival cells during the ozonation process, both human gingival fibroblasts and keratinocytes were exposed to different doses of ozone (20 s, 40 s, 60 s), and its effects were observed with the Olympus IX73 inverted microscope. The contact of ozone with the human primary gingival cells demonstrates cell sensitivity to the action of ozone, this being higher in fibroblasts compared to keratinocytes, but it is not considered toxic because all the changes are reversible at 48 h after exposure.
Formulation and Development of Oral Fast-Dissolving Films Loaded with Nanosuspension to Augment Paroxetine Bioavailability: In Vitro Characterization, Ex Vivo Permeation, and Pharmacokinetic Evaluation in Healthy Human Volunteers

Paroxetine (PX) is the most potent serotonin reuptake inhibitor utilized in depression and anxiety treatment. It has drawbacks, such as having a very bitter taste, low water solubility, and undergoing extensive first pass metabolism, leading to poor oral bioavailability (<50%). This work aimed to develop and optimize palatable oral fast-dissolving films (OFDFs) loaded with a paroxetine nanosuspension. A PX nanosuspension was prepared to increase the PX solubility and permeability via the buccal mucosa. The OFDFs could increase PX bioavailability due to their rapid dissolution in saliva, without needing water, and the rapid absorption of the loaded drug through the buccal mucosa, thus decreasing the PX metabolism in the liver. OFDFs also offer better convenience to patients with mental illness, as well as pediatric, elderly, and developmentally disabled patients. The PX nanosuspension was characterized by particle size, poly dispersity index, and zeta potential. Twelve OFDFs were formulated using a solvent casting technique. A 22 × 31 full factorial design was applied to choose the optimized OFDF, utilizing Design-Expert® software (Stat-Ease Inc., Minneapolis, MN, USA). The optimized OFDF (F1) had a 3.89 ± 0.19 Mpa tensile strength, 53.08 ± 1.28% elongation%, 8.12 ± 0.13 MPa Young’s modulus, 17.09 ± 1.30 s disintegration time, and 96.02 ± 3.46% PX dissolved after 10 min. This optimized OFDF was subjected to in vitro dissolution, ex vivo permeation, stability, and palatability studies. The permeation study, using chicken buccal pouch, revealed increased drug permeation from the optimized OFDF; with a more than three-fold increase in permeation over the pure drug. The relative bioavailability of the optimized OFDF in comparison with the market tablet was estimated clinically in healthy human volunteers and was found to be 178.43%. These findings confirmed the success of the OFDFs loaded with PX nanosuspension for increasing PX bioavailability.
Thermal performance of nanoscale InGaP/GaAs collector‐up heterojunction bipolar transistors investigated by the advanced optimization technique

The effects of thermal‐dissipation structure on the thermal performance of nanoscale InGaP/GaAs collector‐up heterojunction bipolar transistors were investigated by using the advanced hybrid optimization technique, a combination of the three‐dimensional finite‐element method for temperature‐distribution analysis and the technology computer‐aided design tool for power‐performance evaluation. Through adequately locating the thermal‐dissipation structure at the rear side of the transistor and via effective thickness‐thinning procedures, which reduce foundry cost, the thermal coupling between collector fingers has been greatly ameliorated and a power‐added efficiency of 45% is achieved. Copyright © 2013 John Wiley & Sons, Ltd.
Methoden der interferometrischen Formerfassung nicht-ruhender technischer Oberflächen (Methods for Interferometric Contour Measurement of Non Stationary Technical Surfaces)

Abstract Die moderne Qualitätsprüfung technischer Oberflächen erfordert zunehmend berührungslose und zerstörungsfreie Messverfahren. Die Triangulation sowie die Weißlichtinterferometrie erfüllen hier die meisten Anforderungen bezüglich Messgenauigkeit. Zur Messung nicht-ruhender Objekte sind diese Verfahren jedoch meist nur begrenzt geeignet. Die Zwei-Wellenlängen-Speckle-Interferometrie bietet eine interessante Alternative für Einsatzgebiete, bei welchen besonders die Messzeit eine entscheidende Rolle spielt. Es wird ein Messsystem vorgestellt, das die simultane Aufzeichnung aller für die interferometrische Formerfassung notwendigen Daten ermöglicht und somit den Einfluss von Bewegungen weitgehend unterdrücken kann. Eine GPU-basierte (GPU = Graphic Processing Unit) Interferogramm-Auswertung ermöglicht eine hohe Messgeschwindigkeit und Messrate.
Genetic diversity in Colocasia esculenta and Xanthosoma mafaffa in Togo, West Africa

Taro and new cocoyam are root and leaf crops commonly grown in tropical to warm temperate regions. In Togo, they are neglected and underutilised. Here we report the genetic diversity of 26 accessions of taro and 101 accessions of new cocoyam. Analysis of simple sequence repeats revealed low polymorphic information content of 0.43 and 0.25 in taro and new cocoyam, respectively. PCA scatterplots and Neighbour Joining dendrograms based on the SSR data clustered accessions into groups that more-or-less correspond to morphological diversity in both species. AMOVA within and between morphological groups revealed greater variances within groups than between. This indicates weak genetic differentiation between morphological groups, particularly for taro. Genetic diversity was greater among taro cultivars. Taro has a longer history of introduction and dispersal in Africa, and has had more opportunity for multiple introduction and local cultivar development. Different strategies are suggested for future development of these crops in Togo and Africa. For taro, further studies of existing diversity and recent experimental introduction, has spread widely in Africa with little genetic diversity. For this crop, international collaboration is needed to clarify taxonomy, and to introduced further cultivars for evaluation under local conditions in Africa.
Local Dynamic Updating Method of Orebody Model Based on Mesh Reconstruction and Mesh Deformation

In this paper, to update the orebody model based on the given interpreted geological information, we present a local dynamic updating method of the orebody model that allows the interactive construction of the constraint deformation conditions and the dynamic updating of the mesh model. The rules for constructing deformation constraints based on the control polylines are discussed. Because only part of the model is updated, the updated mesh is effective and the overall quality is satisfactory. Our main contribution is that we propose a local dynamic updating method for the orebody model based on mesh reconstruction and mesh deformation. This method can automatically update a given 3D orebody model based on a set of unordered geological interpretation lines. Moreover, we implement a deformation neighborhood region search method based on the specified ring radius and a local constrained mesh deformation algorithm for the orebody model. Finally, we test the method and show the model update results with real geological datasets, which proves that this method is effective for the local updating of orebody models.
Environmental parameters and fertilisers as factors affecting the salicylic acid and total polyphenol contents in sport turfgrasses

ABSTRACT In 2019, we conducted a field experiment to test the effects of three different granular fertilizers on the salicylic acid and total phenolic contents in five different sport turfgrass mixtures under natural conditions. It was one of the first experiments assessing the natural resistance of sport turfgrass in Europe. In five terms, before and after fertilizers applications, we randomly collected turfgrass samples within each plot for chemical analyses. The turfgrass mixtures did not affect the average contents of salicylic acid and total polyphenols. The average contents of both compounds were influenced by the date of evaluation and fertilization scheme. The average content of salicylic acid was significantly the lowest under fertilization scheme C. The highest level of salicylic acid was detected on 18th June under scheme A and the lowest on 28th May, where the salicylic acid content ranged from 0.01 ± 0.00 mg.g−1 under scheme A to 0.017 ± 0.00 mg.g−1 under scheme B and 0.006±0.00 mg.g−1 under scheme C. The content of total polyphenols was higher under fertilization schemes B and C. We conclude that the method of fertilization exerts a certain effect on the salicylic acid and total polyphenol contents in turfgrass mixtures, which also depends on environmental factors.
On the extraction of cyber risks from structured products

ABSTRACT The aim of this paper is to develop an approach to extract information about cyber risks from structured financial products. We consider decision makers that are interested in extracting information about the uncertainty of Cyber risks. The value of information can be evaluated using recently developed entropy approaches in Finance. The underlying idea is that what we call Arrow-Debreu Cyber Risk state prices can be extracted, provided the right structured products be ‘created’. It is shown that different market-based approaches can be used to get a better idea of the shape of the loss distribution facing firms. This information is potentially of interest to evaluate the risk premiums of insurance products. Comparisons between extracted market expectations can also be informative for risk evaluation, notably the distribution of unexpected losses and the eventual shortfall calculations. Finally, recent information-theoretic approaches enable us to make the link between pricing and the value of information to investors.
Ultra-Fast CGRA Scheduling to Enable Run Time, Programmable CGRAs

Coarse-Grained Reconfigurable Arrays (CGRAs) can offer both energy-efficiency and high-throughput for embedded systems today. But, one limitation of CGRAs is the extremely long mapping time that can take many hours to complete for a typical workload. This extended mapping time, coupled with the typical use of a fixed CGRA program configuration, significantly limits potential use cases as well as hinders the ability to achieve the required performance and efficiency targets.To overcome these limitations, we propose a new, low-complexity CGRA mapping algorithm that compiles applications in milliseconds instead of hours. This is achieved by the use of key instruction placement guidelines which enable speedups of up to 800,000 $\times$ while maintaining comparable kernel performance. This result allows, for the first time, the ability to dynamically reconFigure CGRA accelerators to adapt to the scenario at hand, be it an important phase of an application, or a user-generated query or request. Overall, this compiler solution could lay the foundation for improved system throughput and efficiency.
Two-dimensional threshold voltage analytical model of DMG strained-silicon-on-insulator MOSFETs

For the first time, a simple and accurate two-dimensional analytical model for the surface potential variation along the channel in fully depleted dual-material gate strained-Si-on-insulator (DMG SSOI) MOSFETs is developed. We investigate the improved short channel effect (SCE), hot carrier effect (HCE), drain-induced barrier-lowering (DIBL) and carrier transport efficiency for the novel structure MOSFET. The analytical model takes into account the effects of different metal gate lengths, work functions, the drain bias and Ge mole fraction in the relaxed SiGe buffer. The surface potential in the channel region exhibits a step potential, which can suppress SCE, HCE and DIBL. Also, strained-Si and SOI structure can improve the carrier transport efficiency, with strained-Si being particularly effective. Further, the threshold voltage model correctly predicts a "rollup" in threshold voltage with decreasing channel length ratios or Ge mole fraction in the relaxed SiGe buffer. The validity of the two-dimensional analytical model is verified using numerical simulations.
Self-Development Design of Automotive Transmission Based on MASTA Platform

MASTA is the professional CAE software for auto transmission simulation, analysis and design system. Based on this, firstly how to realize the design and optimization of auto transmission assembly is discussed by MASTA system deflection analysis principle, not only are the accuracy of gear strength and modification analyzed through comparison, but also the selection and rating basis of axis and bearing are obtained. In addition, on basis of the full consideration of the whole structure deflection namely the structural flexibility factor, the influence of the housing and alien shafts’ actual rigidity on internal driving system is checked, and the analysis results of gear strength are presented. A new design concept is put forward, which improves design level of gearbox, and reduces the testing time and shortens the product development cycles as well.
Study on the Positioning Accuracy of GNSS/INS Systems Supported by DGPS and RTK Receivers for Hydrographic Surveys

Hydrographic surveys, in accordance with the International Hydrographic Organization (IHO) S-44 standard, can be carried out in the following five orders: Exclusive, Special, 1a, 1b and 2, for which minimum accuracy requirements for the applied positioning system have been set out. They are as follows, respectively: 1, 2, 5, 5 and 20 m, with a confidence level of 95% in two-dimensional space. The Global Navigation Satellite System (GNSS) network solutions (accuracy: 2–3 cm (p = 0.95)) and the Differential Global Positioning System (DGPS) (accuracy: 1–2 m (p = 0.95)) are now commonly used positioning methods in hydrography. Due to the fact that a new order of hydrographic surveys has appeared in the IHO S-44 standard from 2020—Exclusive, looking at the current positioning accuracy of the DGPS system, it is not known whether it can be used in it. The aim of this article is to determine the usefulness of GNSS/Inertial Navigation Systems (INS) for hydrographic surveys. During the research, the following two INSs were used: Ekinox2-U and Ellipse-D by the SBG Systems, which were supported by DGPS and Real Time Kinematic (RTK) receivers. GNSS/INS measurements were carried out during the manoeuvring of the Autonomous/Unmanned Surface Vehicle (ASV/USV) named “HydroDron” on Kłodno lake in Zawory. The acquired data were processed using the mathematical model that allows us to assess whether any positioning system at a given point in time meets (or not) the accuracy requirements for each IHO order. The model was verified taking into account the historical and current test results of the DGPS and RTK systems. Tests have confirmed that the RTK system meets the requirements of all the IHO orders, even in situations where it is not functioning 100% properly. Moreover, it was proven that the DGPS system does not only meet the requirements provided for the most stringent IHO order, i.e., the Exclusive Order (horizontal position error ≤ 1 m (p = 0.95)). Statistical analyses showed that it was only a few centimetres away from meeting this criterion. Therefore, it can be expected that soon it will be used in all the IHO orders.
Novel Galectin-3 Roles in Neurogenesis, Inflammation and Neurological Diseases

Galectin-3 (Gal-3) is an evolutionarily conserved and multifunctional protein that drives inflammation in disease. Gal-3’s role in the central nervous system has been less studied than in the immune system. However, recent studies show it exacerbates Alzheimer’s disease and is upregulated in a large variety of brain injuries, while loss of Gal-3 function can diminish symptoms of neurodegenerative diseases such as Alzheimer’s. Several novel molecular pathways for Gal-3 were recently uncovered. It is a natural ligand for TREM2 (triggering receptor expressed on myeloid cells), TLR4 (Toll-like receptor 4), and IR (insulin receptor). Gal-3 regulates a number of pathways including stimulation of bone morphogenetic protein (BMP) signaling and modulating Wnt signalling in a context-dependent manner. Gal-3 typically acts in pathology but is now known to affect subventricular zone (SVZ) neurogenesis and gliogenesis in the healthy brain. Despite its myriad interactors, Gal-3 has surprisingly specific and important functions in regulating SVZ neurogenesis in disease. Gal-1, a similar lectin often co-expressed with Gal-3, also has profound effects on brain pathology and adult neurogenesis. Remarkably, Gal-3’s carbohydrate recognition domain bears structural similarity to the SARS-CoV-2 virus spike protein necessary for cell entry. Gal-3 can be targeted pharmacologically and is a valid target for several diseases involving brain inflammation. The wealth of molecular pathways now known further suggest its modulation could be therapeutically useful.
A quadrature CMOS clapp voltage‐controlled oscillator

A new fully integrated, CMOS Clapp quadrature voltage‐controlled oscillator (QVCO) is presented.The QVCO is composed of two differential n‐core Clapp VCOs coupled by four pMOSFETs and was implemented in the 0.18‐μm CMOS technology with 0.9‐V supply voltage. The die area is 0.574 × 0.866 mm2. At the supply voltage of 0.9 V, the total power consumption is 12.2 mW. The free‐running frequency of the QVCO is tunable from 7.89 to 9.3 GHz as the tuning voltage is varied from 0 to 2 V. The measured phase noise at 1‐MHz frequency offset is −118.65 dBc/Hz at the oscillation frequency of 7.89 GHz, and the figure of merit of the proposed QVCO is about −185.71 dBc/Hz. © 2011 Wiley Periodicals, Inc. Microwave Opt Technol Lett, 2011; View this article online at wileyonlinelibrary.com. DOI 10.1002/mop.26109
Theoretical Road Damage Due to Dynamic Tyre Forces of Heavy Vehicles Part 1: Dynamic Analysis of Vehicles and Road Surfaces

Theory is presented for simulating the dynamic wheel forces generated by heavy road vehicles and the resulting dynamic response of road surfaces to these loads. Sample calculations are provided and the vehicle simulation is validated with data from full-scale tests. The methods are used in the accompanying paper to simulate the road damage done by a tandem-axle vehicle.
Differential inductive displacement sensor with integrated electronics and infrared communication capabilities

Differential inductive displacement sensors are widely used in hydraulic applications because they offer good accuracy, large displacement range (up to 200mm) and have a rugged construction. Displacement information is usually extracted with analog electronics techniques - sinusoidal excitation of coils, quadrate modulation and synchronous demodulation – but this method is not well suited for implementation in digital embedded systems. Using a novel method for displacement measurement, based on switching voltages applied to the coils of the inductive device, the displacement sensor can be implemented with a standard microcontroller with integrated analog to digital converter and timer. Commissioning, configuring and data communication can be performed using standard serial interface. To avoid wires and cables, an infrared communication based on a standard IrDA transceiver module can be implemented. Presented paper focuses on measurement and construction aspects of an inductive displacement sensor with infrared communication interface option implemented and tested by authors.
PEMANFAATAN SMARTPHONE ANDROID OLEH MAHASISWA ILMU KOMUNIKASI DALAM MENGAKSES INFORMASI EDUKATIF

The development of Technologi Information and communication media in now,to be present is very quikly of communication media on turning in people. It’s Because the biggest innovation and metamorphosis in communication in this era. For example we can see that it’s very much people used handphone for media of communication’s from someone to other ‘s in another place.An Smartphone Android it is a new techonologi in communication media in people now. The Used of media smartphone android we can saw in Student’s circle. The use a smart phone to be our knowlage is using on access education information. The Study to be present about Uses of the Smartphone Android by Communication Student’s to be acces the education information. It’s because the communication student’s as spesially lerned about various information media in teory and applicatied and communication student also lerned the communication aspect in reciving information of media. The study stay in communication studen’s in Faculty Social and Political Sciance of Sam Ratulangi University. Keyword : Smartphone Android, Communication Student’s, Education Information.