Miracle-dz/UniFAR-FTUs huggingface dataset:
Comp arative efficacy of sorafenib vs. best supporti ve care in recurren t hepat ocellula r carcinoma after liver tran splantation: A case-contro l study

Backgroun d & Aims : The efficacy of sorafenib in the post-liver transplan tation (LT) setting has been scarcely studied. The aim of this study was to evaluate the efficacy of sorafenib, compared to best suppor tive care (BSC), in two cohorts of patients which presented with hepatocell ular carcinoma (HCC) recurrence after LT. Methods: Data from patients who developed presentat ion or progression of HCC recurrence after LT not amenabl e to surgic al/ locoregio nal treatmen ts (untreatable presentat ion/progress ion, UP) were retrieved. The cohort of patients receivi ng sorafenib starting from 2007 was compared to that of patients receiving BSC in the previous era. Disease outcome was investigat ed in terms of survival from recurre nce or from UP by means of univariate and multiv ariate Cox regression models with event times left-truncat ed at the date of UP. Results: Of a total of 39 patients, 24 received BSC and 15 sorafenib. The two groups were well matched at baseline, with timerelated imbalanc es regarding mTOR-based immun osuppression and median time from LT to recurrence, significantly higher in the sorafenib group. Patients ’ outcome in the sorafenib group was significantly improved (median survival from recurren ce 21.3 vs.11.8 months, HR = 5.2, p = 0.0009; median survival from UP 10.6 vs. 2.2 months, HR = 21.1, p <0.0001). The only factor associated with survival after HCC recurren ce in multivar iate analysis was treatment with sorafenib (HR = 4.0; p = 0.0325). No severe adverse event was registered in this post-LT setting. Conclus ions : Although the use of historical controls weakens final interpreta tion, sorafenib seems to be associ ated with an acceptable safety profile and benefit in surviva l in HCC patients suffering recurren ce after LT. 2013 Europea n Associat ion for the Study of the Liver. Published
Functionalization of Carbon Nanotubes and Polymer Compatibility Studies

Multiwalled carbon nanotubes (MWNTs) were oxidated and functionalized in order to determine the structural and chemical changes on their atomic bonding. MWNTs were oxidized in an aqueous solution of HNO3 (70%) and H2SO4 (95%) at 25 °C. Pristine and oxidized carbon nanotubes (ox-MWNTs) were characterized by scanning electron microscopy (SEM), Fourier transform infrared spectroscopy (FTIR), Raman spectroscopy, and thermogravimetrical analysis (TGA). MWNTs and ox-MWNTs were silane-functionalized and incorporated into a polymethyl-methacrylate (PMMA) matrix. The dispersion properties and interface interactions were studied for the composite materials. MWCNTs oxidation was performed and supported by Raman spectroscopy and FTIR results of disorder and defects in the carbon lattice; as well as change in the amount and type of chemical groups attached to the CNTs walls. Roughness areas visible in SEM images indicate Van der Waals interactions between CNTs and functionalization reagents. Control of the oxidation state can effectively direct molecular functionalization of a CNT sidewall. Composites showed good dispersion of filler; with the best one for oxidized-silane functionalized CNTs.
Attitudes toward COVID-19 Vaccination on Social Media: A Cross-Platform Analysis

During the COVID-19 pandemic, social media content analysis allowed for tracking attitudes toward newly introduced vaccines. However, current evidence is limited to single social media platforms. Our objective was to compare arguments used by anti-vaxxers in the context of COVID-19 vaccines across Facebook, Twitter, Instagram, and TikTok. We obtained the data set of 53,671 comments regarding COVID-19 vaccination published between August 2021 and February 2022. After that, we established categories of anti-vaccine content, manually classified comments, and compared the frequency of occurrence of the categories between social media platforms. We found that anti-vaxxers on social media use 14 categories of arguments against COVID-19 vaccines. The frequency of these categories varies across different social media platforms. The anti-vaxxers’ activity on Facebook and Twitter is similar, focusing mainly on distrust of government and allegations regarding vaccination safety and effectiveness. Anti-vaxxers on TikTok mainly focus on personal freedom, while Instagram users encouraging vaccination often face criticism suggesting that vaccination is a private matter that should not be shared. Due to the differences in vaccine sentiment among users of different social media platforms, future research and educational campaigns should consider these distinctions, focusing more on the platforms popular among adolescents (i.e., Instagram and TikTok).
PROPAGATION OF HARMONICAL VIBRATIONS IN PEAT

In order to check the reliability of man-made vibration prediction methods, vibration tests were performed on one of polders in the North-West of the Netherlands. The polder was chosen because it has a rather homogenous, thick and soft peat top layer. Here sufficient harmonical vibrations could be generated by a rather small shaker. The shaker was designed and manufactured in order to produce harmonical vibrations at the soil surface. It consists of two counter rotating electric vibrators (with rotating eccentric masses) in order to produce a vertically oscillating force. For the recordings of the vibrations, six 2D or 3D geophones were placed on the soil surface and one 2D geophone was placed on top of the shaker. The measured vibration amplitudes of the vertically oscillating shaker were compared with 1. Two different analytical methods used for the design of vibrating machine foundations, 2. The Confined Elasticity approach and 3. The Finite Element Method, for which Plaxis 2D software was used. Also the measured vibration amplitudes at the soil surface were compared with Barkan- Bornitz's solution and Finite Element Modeling.
Effect of oral a-tocopherol and zinc on plasma status, IGF-I levels, weight gain and immune response in young calves

Thirty newborn calves were supplemented with α-tocopherol (vit. E) (n=10), zinc (Zn) (n=10) or nothing (control) (n=10) for 8 weeks. All calves were vaccinated against tetanus at week 5. Plasma Zn and α-tocopherol were signifi cantly increased in the Zn and vit. E groups, respectively. Plasma IGF-I levels generally increased from birth to week 8, but were not affected by Zn or vit. E. Daily weight gain was highest in the Zn group, but this was not related to an increased IGF-I level. The vit. E group responded earlier than the Zn and control groups to the tetanus vaccination.
Economic Structure, International Income Differentials and Long-Run Growth

In a well-known paper on the structure of development, Leontief (1963) showed that a country's degree of economic development could be assessed by the relative completeness of its economic structure. This pattern of development is modelled in this paper. Within a context of international trade, and assuming that the world distribution of labour is given, the model yields that a sufficiently large differential between the economic structures of developed (Northern) and underdeveloped (Southern) economies induces Southern countries to accept lower prices for their basic goods and endure lower incomes. Economic diversification in the South is analysed as an outcome of technological imitation. The model yields that, even if technological knowledge is a public good, a minimum level of quality education is necessary for long-run growth to take place in the South.
Reconfigurable Particle Separation by Dynamic Acoustic Fields in Microfluidic Devices

Advances in diagnostics, cell and stem cell technologies drive the development of application specific tools for cell and particle separation. Acoustic micro-particle separation offers a promising avenue for label-free, high recovery, cell and particle separation and isolation in tissue engineering and targeted drug delivery. In this paper, we present two methods of separating particles in a microfluidic channel. The first method uses custom-made micro-particles and by changing the acoustic contrast factor, the micro-particles shift from acoustic node to antinodes, compared to commercialised micro-particles. The second method relies on shifting the acoustic standing wave in a pattern called dynamic acoustic field. We demonstrate that both methods separate particles up to 100%.
α-Amylase inhibition and antioxidant activity of Singhnad Guggul in vitro

Background & Aim: Singhnad Guggulu is a traditional Ayurvedic formula for detoxifying and rejuvenating the joints. The present study was to investigate the α-amylase inhibition and antioxidant activities of aqueous extract of Singhnad Guggul (AESG). Experimental: α-Amylase inhibition assay by dinitro-salicylic acid method and antioxidant activity by ferric chelating and ferrous reducing assay. Results: AESG indicated that potent α-amylase inhibition activity (IC50= 84.00 µg/ml). AESG also showed ferric chelating and ferrous reducing activities. Recommended applications/industries: Our studies showed that
Analyzing Changes in View During Argumentation: A Quest for Method

Unter Psycholog(inn)en und Erzieher(inne)n besteht ein steigendes Interesse an Wissensbildungsprozessen in Lehr- und Lernsituationen. Das wesentlichste Problem, dem die Forschenden bei diesem Versuch begegnen, besteht im Fehlen geeigneter analytischer Instrumente. In einer solchen Lage ist man verfuhrt, in anderen Bereichen nach dort entwickelten Herangehensweisen zu suchen und sie ggf. zu "ubernehmen". Leider ignorieren viele Wissenschaftler(innen) bei derartigen methodischen "Importen", wofur die ubernommenen Methoden ursprunglich entwickelt wurden. Insoweit ist es nicht uberraschend, dass mit diesen Methoden durchgefuhrte Studien dann oft die Fragestellungen der Forschenden in anderen Wissenschaftsfeldern schlichtweg verfehlen. Im Folgenden wird genau dieses Risiko des Importierens von Methoden eines Fachgebiets in ein anderes diskutiert. Konkret handelt es sich um die Ubernahme von Ansatzen der Argumentationstheorie und von Strategien zur Untersuchung von Diskursen in Forschungsarbeiten uber Lernprozesse, und zwar auf eine Art und Weise, als seien diese Verfahren ohne weitere Prufung und Anpassung auch in diesem Feld anwendbar. Entgegen einer solchen Vorgehensweise soll im vorliegenden Beitrag gezeigt werden, dass in anderen Kontexten entwickelte Verfahren zwar eine wichtige Rolle fur die Beschreibung und fur das Verstehen von Argumentationsverlaufen bieten konnen, allerdings ist es unabdingbar, dass zusatzliche Dimensionen einbezogen werden, wenn die Diskurs-Mediation in Lehr- und Lernprozessen untersucht werden soll. URN: urn:nbn:de:0114-fqs0103123
. A corpus linguistic approach to the identification of swearing in computer mediated communication

The study of swearing has increased in the last decade, diversifying to include a wider range of data and methods of analysis. Nevertheless, certain types of data and specifically large corpora of computer mediated communication (CMC) have not been studied extensively. In this paper, we fill a gap in research by studying the use of swearwords in blog data, and illustrate ways of identifying swearing in a large corpus by taking context into account. This approach, based on the examination of shared and unique collocates of known expletives, facilitates the distinction of attestations of swearing from non-swearing in the case of polysemous lexemes, and the analysis of overlaps in usage and meaning of swearwords. This work therefore goes beyond basic sentiment analysis and offers new insights into the use of collocation for refining profanity filters, providing innovative perspectives on issues of growing importance as online interaction becomes more widespread.
Two-Degree-of-Freedom H8 Optimization and Scheduling for Robust Vehicle Lateral Control

In this paper, the problem of automatic vehicle steering is addressed using a two-degree-of-freedom loop shaping procedure. The controller is split into two parts. The closed loop part achieves the robust stability requirement while the prefilter part processes the reference signal and is designed to achieve model matching. The whole synthesis procedure is emphasized and the controller is tested in various situations with several system parameter variations. The observer structure of the controller is finally exploited in order to consider scheduling controllers according to vehicle speed variations. The advantages of the controller scheduling are outlined with some simulation results.
Emissions Analysis of Southern California Metrolink Commuter Rail

The Southern California Regional Rail Authority began constructing a new commuter rail system called Metrolink in October 1992. When complete, the Metrolink system will form the nation's sixth largest commuter rail system and is expected to alleviate congestion and help obtain better air quality. To estimate the air quality impact, emissions of CO, HC, NOx, and PM associated with an automobile-only–based commute and a Metrolink-based commute from Riverside to Los Angeles are compared. Analysis of the Metrolink-based commuting scenario includes the emissions from the home-to-station automobile trip and the Metrolink diesel locomotive emissions. Essential data for the automobile emissions modeling process were obtained through a survey of Metrolink passengers and through remote emissions sensing of Metrolink passenger vehicles. Train emissions were estimated using emission rate data provided by recent diesel locomotive studies. Results indicated that at current ridership levels there is a reduction in total amount of all four pollutants combined through Metrolink commuting. On a pollutant-by-pollutant basis, it was estimated that the Metrolink commuting scenario reduces the emissions of CO and HC relative to the automobile-only commuting scenario; however, it increases the emissions of NOx and PM. The minimum amount of Metrolink ridership required to get a net emissions reduction from the system is predicted.
Dominant height growth of European beech at the northeasternmost stands in Europe

The height growth of trees influences the productivity of stands and the competitiveness of species, shaping the range of their distribution. Dominant height growth was assessed for European beech (Fagus sylvatica L.), growing outside of its natural distribution range in the western part of Latvia. In 10 neighbouring experimental stands, 20 dominant trees were felled for stem analysis. Height growth was modelled using the generalised algebraic difference approach, applying several non-linear equations and mixed procedures. The Chapman-Richards and Sloboda models showed the best fit to the data. Height growth of the second generation (younger) trees exceeded that of the first generation, and followed curve for a higher site index, suggesting sufficient adaptation and improving conditions. Height growth of the studied beech exceeded predictions for beech in southern Sweden, which is considered to be the northern limit of the species range, yet the growth pattern differed. In Latvia, slower height growth was estimated for site indices < 32 m (in 100 years) during the first 60 years, yet larger maximal height was predicted, suggesting a longer establishment period. Nevertheless, the improving height growth indicated increasing potential for the application of the species in commercial forestry, and an expansion of the species within the region even during the 21th century.
PROPOSED MODEL FOR THE SUCCESSFUL IMPLEMENTATION OF MANAGEMENT INFORMATION SYSTEMS IN YEMENI ORGANIZATIONS

In information systems era, data have become one of the most important resources to organizations . Management information system one of the most important tools in any organization , which aims to provide reliable ,complete ,accessible, and understandable information in a timely manner to the users of the system . In addition increase the organizational performance and labor productivity . There are several characteristics to the success or failure of the implementation of management information systems in organizations. Most of existing model focus heavily on technology characteristics or compared to organizational characteristics and human characteristics . This study will focus on all the characteristics for MIS success. This study combines four theories namely as technology acceptance model ,information system success model , computer usage model ,and personal computing acceptance model . The aim of this study to develop proposed model for successful adoption of MIS in Yemeni organizations.
BIOCHEMICAL AND MOLECULAR STUDIES OF THE ANTI- PHYTOPATHOGENIC TRAIT IN ACTINOMYCETES

Two actinomycetes isolates, Streptomyces shandonggensis AUDT 217 and Streptomyces parvus AUDT 248, isolated from rhizospheric soils, were evaluated for their anti-phytopathogenic activity against Colletotrichum sp. , Rhizoctonia solani, Sclerotium rolfsii and Ralstonia solanacearum. Dual culture bioassay of the selected isolates showed significant antimicrobial activity against the phytopathogens. Pot assay experiment using cell free culture filtrates of AUDT 217 and AUDT 248 exhibited 69 percent and 77 percent disease control of groundnut stem rot caused by Sclerotium rolfsii, respectively. Spraying of cell free culture filtrates of AUDT 217 and AUDT 248 also showed lower sheath blight intensity (SBI) of 10.13 percent and 8.39 percent in rice respectively, compared to control plant with 23.584 percent SBI. GC-MS analysis of the crude secondary metabolites detected several compounds with diverse biological activity. Antimicrobial compounds viz., tert-Butyl-pbenzoquinone, Benzeneacetamide, Benz[a]anthracene, 8-methyl, etc., antifungal compounds (Diethyl Phthalate, Phenylethyl Alcohol, Phenol, 2, 4-bis(1,1-dimethylethyl)-, etc.) and antibacterial compound (tert-Butyl-p-benzoquinone) were from detected from AUDT 217. Interestingly, lumichrome which is known to stimulate plant growth was also detected with the area coverage 0.18 percent and 55 percent purity. Among the prominent compounds produced by AUDT 248, 4, 6-Dimethyl-2-thioxo-1, 2dihydro-3-pyridinecarbonitrile, (antimicrobial), Benz[a]anthracene, 8-methyl(antitumur), and Naphthalenone, cisoctahydro-8a-methyl, (insecticidal) can be highlighted. Two important domains of PKS gene cluster i.e., partial keto synthase and acyl transferases were cloned from both the isolates in order to have better understanding of genetic basis of secondary metabolites production. Clones AUDT 248.1 and AUDT 248.2 showed 85 percent to 88 percent homology with putative modular polyketide synthase gene of Streptomyces ambofaciens ATCC 23877 right chromosomal arm (AM238664.2), which showed its potential to produce stambomycin antibiotics.
Performance of Networked Control Systems

Data packet dropout is a special kind of time delay problem. In this paper, predictive controllers for networked control systems (NCSs) with dual-network are designed by model predictive control method. The contributions are as follows. (1) The predictive control problem of the dual-network is considered. (2) The predictive performance of the dual-network is evaluated. (3) Compared to the popular networked control systems, the optimal controller of the new NCSs with data packets dropout is designed, which can minimize infinite performance index at each sampling time and guarantee the closed-loop system stability. Finally, the simulation results show the feasibility and effectiveness of the controllers designed.
International Comparisons of Levels of Capital Input and Multi-Factor Productivity

Abstract The paper uses a method by Christensen et al. to construct crosscountry comparisons of the levels of capital input, capital and labour productivity and multi-factor productivity. These results are used to decompose international differences in gross domestic product per capita into differences in labour utilization, information and communication technology (ICT) and non-ICT capital intensity and multi-factor productivity for seven Organisation for Economic Co-operation and Development countries. We provide Monte Carlo estimates to examine the effects of measurement errors in the base data, and these simulations showed that boundaries for the resulting indicators can be important.
Stakeholders' expectations on ecosystem services affect the assessment of ecosystem services hotspots and their congruence with biodiversity

The congruence of ecosystem services (ESs) and the congruence of ES ‘hotspots’ and ‘hotspots’ of biodiversity are receiving growing interest. The thresholds used in such analyses to assess the ES presence vary widely but their effects have not been questioned. We provide an analysis of the effect of the choice of these thresholds on the overlap among ESs and the distribution of hotspots. Focusing on grasslands from the Central French Alps, we first systematically varied thresholds for three ESs (agronomic, regulation and aesthetic values), then considered triplets of thresholds representing three contrasted stakeholder perspectives on the importance of each of these services. Overlap between ESs depended strongly on thresholds. The extent of ES hotspots and their overlap with biodiversity hotspots varied widely across perspectives. Coldspots never overlapped with areas of interest for biodiversity, whatever be the perspective. Overlap was less informative than the diagnostic test of the capacity of individual ESs to capture each other's distribution. Agronomic value poorly captured other ESs. Biodiversity was well captured by regulation and aesthetic values, but poorly captured by service hotspots. This analysis emphasizes the importance of accounting for varying stakeholders' expectations in ES hotspot assessments.
Types of fishing gears operating and their impact on Krishna river fishery in Mahabubnagar district, T.S. India

Fishing gears and their impact on Krishna river fishery in Mahabubnagar district was investigated from 2012 to 2014. Documentation of gears in rivers of India is scanty. The paper describes a wide range of traditional as well as modernized fishing gears used by subsistence and professional fishers in the river Krishna and their impact on the fisheries and ecosystem of the same. The minute mesh size fishing gears, like seine nets used in the catching of all sizes of fish impacting the fisheries of the river. The use of this kind of fishing gears is also the major cause of sharp decline of the economically important Indian major carps in the river. An awareness programs should be extended amongst the fishers to create awareness of the long-term effects of their fishing practices and to impart knowledge of fishing laws. The present account is an attempt to document the occurrence of 5 different kinds of gears, lines and nets in the entire stretch of the Krishna river in the district. The objective of study is to present the recent data of fishing gears and nets operated for fishing in the river and their impact on the Krishna fishery.