Miracle-dz/UniFAR-FTUs huggingface dataset:
Experimental Investigation of Mechanical and Chemical Properties of Aluminium Reinforced with MWCNT

Carbon Nanotubes (CNT’s) have recently been found to possess extraordinary mechanical, thermal and electrical properties. Extensive studies on the properties of CNT’s as a re-inforcing agent in Metal Matrix Composites are being investigated. In this study, powder metallurgy technique has been employed for the matrix material being Aluminium 6063 with CNT in varying concentrations as reinforcing agent. The powders are mixed thoroughly using ball milling and are compacted in a compacting die made of D-2 Steel to make green compact. It is then sintered at 350°C to 550°C at a rate of increase of 50°C per hour. Chemical, Microscopic examination, Compression and Hardness tests were performed on the specimens and were compared with pure aluminium specimens to show the effects of varying concentrations of CNT. The study indicated that there was no improvement in hardness of the composite on addition of CNT while there was an increase in compressive strength. The microstructure of pure aluminium and Al-CNT composite had fine grains of pure aluminium particles and Al-Si eutectic particles throughout the matrix phase.
BOLA3 is a prognostic-related biomarker and correlated with immune infiltrates in lung adenocarcinoma.

BACKGROUD BolA gene family contains three members, high expression of BolA family member 2 (BOLA2) has been reported to be associated with prognosis of several cancers. However, the relationship between BOLA3 and lung adenocarcinoma (LUAD) remains unclear. METHODS Expression of BOLA3 was analyzed by online database. Co-expressed genes and gene set enrichment analysis (GSEA) were performed using LinkedOmics. Diagnostic value was assessed using receiver operating characteristic (ROC) curves. The prognostic value of BOLA3 was analyzed using Prognoscan and Kaplan-Meier Plotter. The Tumor Immune Estimation Resource (TIMER) and Single-sample Gene Set Enrichment Analysis (ssGSEA) were used to explore the relationship between BOLA3 and tumor immune infiltration. RESULTS The results showed that the expression of BOLA3 was significantly higher in LUAD than in normal tissues. High expression of BOLA3 was associated with T stage, N stage, pathologic stage (all P < 0.001). In addition, elevated expression of BOLA3 was associated with overall survival (OS) and progression-free survival (PFS) in LUAD ((OS:HR = 2.58, log-rank P = 1.3e - 11; PFS:HR = 2.36, log-rank P = 4.1e - 05). BOLA3 expression level has negative correlations with infiltrating levels of B cells, CD4 +T cells, macrophages, neutrophils, and dendritic cells (DCs). GSEA analysis showed BOLA3 joined mainly in mitochondrial respiratory chain complex assembly, translational initiation, etc. CONCLUSIONS: These results showed up-regulated in BOLA3 was correlated with poor prognosis and immune infiltrates in LUAD, BOLA3 can be served as a potential immunotherapy target.
A Longitudinal Examination of Enacted Goal Attention in End-of-Life Communication in Families

Drawing on theoretical principles related to goal pursuit and inference, the present study investigated the extent to which specific message features led to better or worse conversational outcomes of end-of-life discussions between older adults and their adult children. Actor-partner interdependence modeling analysis of longitudinal reports from 66 parent/child dyads revealed that tactical attention to identity, relational, and task goals in conversation predicted change over a 1-year period in advance directive completion, concordance accuracy, and relationship satisfaction and closeness. Quantity features of communication (i.e., number of conversations, number of topics discussed) were not related to the measured outcomes. Routine relationship maintenance and explicit decision making had a positive impact on the outcomes, and underaccommodation, strategic relationship maintenance, avoidance, elaboration, and implicit decision making had a negative impact on the outcomes of end-of-life family talk. The findings provide insight on how to practically improve the quality of end-of-life conversations in families.
The Impact of Group Testing as a Strategy on University ‎Students’ Writing Composition Development ‎

In academic writing, students at universities struggle when they write a short composition in English as a foreign language. Process writings, such as brainstorming, drafting, obtaining feedback, and rewriting, are pedagogical techniques that are widely utilized to teach writing composition in a foreign linguistic communication in parliamentary procedure to develop writing skills. Teachers frequently, use groups work from which students can benefit when there is positive social interaction. EFL students learn better when they incorporate together and can share their strengths and weaknesses of ideas with others in an effective way, as students complete a composition task with assistance that they may not be able to do individually. Nevertheless, some instructors are reluctant to incorporate group testing activities in writing class. In this study, the researchers investigate the impact of group testing as an assessment strategy on writing composition development. To achieve the aim of this study, a quasi-experimental research design with two types of tests (individual test and group testing) were used. Results revealed that group testing provides a good influential assessment strategy to enhance students’ performance in a composition and has a positive effect on long-term retention and enrich their thinking process on subsequent development of writing composition.
Wearable Sensors for Vital Signs Measurement: A Survey

With the outbreak of coronavirus disease-2019 (COVID-19) worldwide, developments in the medical field have aroused concerns within society. As science and technology develop, wearable medical sensors have become the main means of medical data acquisition. To analyze the intelligent development status of wearable medical sensors, the current work classifies and prospects the application status and functions of wireless communication wearable medical sensors, based on human physiological data acquisition in the medical field. By understanding its working principles, data acquisition modes and action modes, the work chiefly analyzes the application of wearable medical sensors in vascular infarction, respiratory intensity, body temperature, blood oxygen concentration, and sleep detection, and reflects the key role of wearable medical sensors in human physiological data acquisition. Further exploration and prospecting are made by investigating the improvement of information security performance of wearable medical sensors, the improvement of biological adaptability and biodegradability of new materials, and the integration of wearable medical sensors and intelligence-assisted rehabilitation. The research expects to provide a reference for the intelligent development of wearable medical sensors and real-time monitoring of human health in the follow-up medical field.
Evaluation of Solar Drying on Drying Behaviour and Drying Kinetics of Penaeus vannamei

ABSTRACT This work aimed to evaluate the effects of solar drying (SD) on physico-chemical properties, drying kinetics, and energy consumption to dry Penaeus vannamei, considering natural drying (ND) and hot-air drying (HD) as references. Compared with ND and HD, SD exhibited the shortest time when the moisture content (MC) was reduced from 73% to 18%, and the effective moisture diffusivity was in the range of 151.26 × 10-10 to 9.26 × 10-10 m2s-1. The two-term model was the most suitable for fitting of the drying curves by analyzing six theoretical models. Additionally, the superior texture, brighter color, and higher sensory scores were obtained by SD. SD application brought about changes in shrinkage and rehydration. And the different drying methods presented significant effects on energy consumption; of which, SD saved the most energy (3.00 kWh). Impact analysis showed that SD is a suitable solution for preserving Penaeus vannamei with environmental sustainability.
THE FOUNDATION OF DEVELOPING CHARACTER BUILDING IN HAMZANWADI NAHDHADUL WATHAN DINIYAH ISLAMIYAH (NWDI) ISLAMIC BOARDING SCHOOL IN EAST LOMBOK

The issues of character-building quality and morality in Indonesia still become everyday tasks. A high rate of crime and violence occurs in ordinary people's life. Many younger generations, particularly school-age kids, were engaged in promiscuity, brawls, fight, et cetera. Thus, for solving the youth generation problem from an early age, improving character building is necessary. Islamic boarding school has a very strategic role in building character. The study is qualitative research with a study case in Hamzanwadi Nahdhadul Wathan Diniyah Islamiyah (NWDI) Islamic boarding school through an interview, thorough discussion, and direct observation in the research site. The study shows that the foundations for developing character building are religious, philosophical, and empirical. These three foundations make Hamzanwadi Diniyah Islamiyah (NWDI) Pancor Islamic boarding school still exists and become exemplary for other Islamic boarding schools in developing character building. The character built corresponds to the expectation of the Islamic boarding school founder
A Deep Learning Approach for Recognizing the Cursive Tamil Characters in Palm Leaf Manuscripts

Tamil is an old Indian language with a large corpus of literature on palm leaves, and other constituents. Palm leaf manuscripts were a versatile medium for narrating medicines, literature, theatre, and other subjects. Because of the necessity for digitalization and transcription, recognizing the cursive characters found in palm leaf manuscripts remains an open problem. In this research, a unique Convolutional Neural Network (CNN) technique is utilized to train the characteristics of the palm leaf characters. By this training, CNN can classify the palm leaf characters significantly on training phase. Initially, a preprocessing technique to remove noise in the input image is done through morphological operations. Text Line Slicing segmentation scheme is used to segment the palm leaf characters. In feature processing, there are some major steps used in this study, which include text line spacing, spacing without obstacle, and spacing with an obstacle. Finally, the extracted cursive characters are given as input to the CNN technique for final classification. The experiments are carried out with collected cursive Tamil palm leaf manuscripts to validate the performance of the proposed CNN with existing deep learning techniques in terms of accuracy, precision, recall, etc. The results proved that the proposed network achieved 94% of accuracy, where existing ResNet achieved 88% of accuracy.
Make Movement Your Mission: Evaluation of an online digital health initiative to increase physical activity in older people during the COVID-19 pandemic

Objective To formatively evaluate the Make Movement Your Mission (MMYM) digital health initiative to promote physical activity (PA) levels and help avert the negative consequences of sedentary behaviours in older adults during the SARS-CoV2 pandemic. Methods Mixed-method study to explore activity levels, changes in physical function and Activities of Daily Living (ADLs), quality-of-life, social engagement, technology use, and accessibility. Survey data were analysed descriptively. Qualitative interviews were analysed using framework analysis. Results Forty-one respondents completed the survey (Mean age 68.4 (8.9) years; 34 Female), 68% aged ≥ 65 years. Average attendance was 14.3 sessions per week (3.5 h). 73% had been with MMYM for >1 year, 90% reported they were engaging in more movement on a typical day, and 75% reported improvement in ability to perform moderate PA. Since starting MMYM, participation in activities targeting strength, balance and flexibility increased (by 48%, 73% and 75%, respectively). 83% met strength and 90% balance PA guidelines for health (≥ 2x per week). Between 18% and 53% of respondents reported improvements in ADLs, 53% reported better quality-of-life, and 28% increased use of the internet. Eight participants were interviewed (Mean age 70.7 (6.7) years; 7 Female). Activity levels were promoted by having direct support from the instructor through Facebook messages pre and post live sessions, having group expectation about quality and level of engagement, having a sense of control and encouragement from others, MMYMs regularity, choice around level of engagement and accessibility. Noticing short-term outcomes in balance and posture helped boost confidence and continued participation. Conclusion Clinical trials need to robustly assess its effectiveness and acceptability.
Attachment of Chiral Functional Groups to Modify the Activity of New GPx Mimetics

A series of new chiral benzisoselenazol-3(2H)-ones and their corresponding diselenides bearing an o-amido function substituted on the nitrogen atom with various aliphatic and aromatic moieties were synthesized. All derivatives representing pairs of enantiomers or diastereoisomers were obtained to thoroughly evaluate the three-dimensional structure–activity correlation. First, bensisoselenazol-3(2H)-ones were synthesized by reacting 2-(chloroseleno)benzoyl chloride with an appropriate enantiomerically pure amine. Then, the Se–N bond was cleaved by a reduction–oxidation procedure using sodium borohydride and then air oxidation to obtain the corresponding diselenides. All derivatives were tested as antioxidants and anticancer agents. In general, the diselenides were more reactive peroxide scavengers, with the highest activity observed for 2,2′-diselenobis[N-(1S,2S)-(-)-trans-2-hydroksy-1-indanylbezamide]. The most cytotoxic derivative towards human promyelocytic leukemia HL-60 and breast cancer MCF-7 cell lines was N-[(1S,2R)-(-)-cis-2-hydroksy-1-indanyl]-1,2-benzizoselenazol-3(2H)-one. The structure–activity relationship of the obtained organoselenium derivatives was discussed.
Effects of aerated subsurface drip irrigation on rhizosphere soil environment and pepper (Capsicum annum L.) growth in three soil types

ABSTRACT Aerated subsurface drip irrigation (ASDI) has been considered an effective method to unlock the growth potential of crops. An experiment was undertaken to monitor the effects of three aeration rates (40% aeration rate, 15% aeration rate, CK: no-aeration) on rhizosphere soil environment and growth parameters of pepper in three soil types (YC: yellow clay, SL: silt loam, HL: heavy loam). ASDI significantly increased the soil enzyme and microbial abundance, and enhanced the soil respiration compared to the control. ASDI significantly increased the pepper yield, fruit quality, and biomass of stem and leaf. The 40% aeration rate was more beneficial to these parameters than that of 15% aeration rate in YC and SL, whereas, in HL, the 40% was less effective than 15% aeration rate. Soil type significantly affected pepper rhizosphere soil environment and the yield, quality, and biomass of stem and leaf. The benefits of ASDI in YC were better than those in SL and HL. However, aeration rate and soil type had no significant effects on the fresh/dry weight of pepper root. The recommended ASDI patterns for pepper in YC and SL were 40% aeration rates, while in HL it was the 15% aeration rate.
Challenges and Plans for the Proton Injectors

The flexibility of the LHC injectors combined with multiple longitudinal beam gymnastics have significantly contributed to the excellent performance of the LHC during its first run, delivering beam with twice the ultimate brightness with 50 ns bunch spacing. To meet the requirements of the High Luminosity LHC, 25 ns bunch spacing is required, the intensity per bunch at injection has to double and brightness shall almost triple. Extensive hardware modifications or additions are therefore necessary in all accelerators of the injector complex, as well as new beam gymnastics.
LCA-based Optimization of Window-wall Ratio and Window Materials of Typical Office Building in Shanghai

In this paper,taking an office building in Shanghai as the research object,the method of LCA was used to study the influences of window-wall ratio on environment,the detailed analysis included different orientations and different window types.The results indicated that the window-wall ratio of common type window had greater impact on the assessment than that of the hollow glass window and Low-E hollow glass window.Furthermore,in order to improve the influence of building life-cycle on environment,optimizing the window materials was more effective than controlling the window-wall ratio.
Properties of Micro-Arc Oxidation Coatings on 5052 Al Alloy Sealed by SiO2 Nanoparticles

Micro-arc oxidation (MAO) treatment can effectively improve the wear resistance, corrosion resistance, and mechanical strength of aluminum alloy substrates. Improving the porous structure of MAO film and effectively sealing the pores is a significant research issue. In this study, the MAO treatment of 5052 aluminum alloy was carried out in silicate electrolytes. The MAO films were sealed with different concentrations of SiO2 nanoparticles. The effects of SiO2 nanoparticle content on the MAO films’ microstructure, mechanical properties, and corrosion performance were systematically investigated. When adding SiO2 nanoparticles to electrolytes, the particles were deposited at the micropores of the film, which could effectively seal the porous MAO film and significantly improve its corrosion and wear resistance. The corrosion resistance and wear resistance properties were optimal with 5.0 g/L SiO2 addition. Compared to the unsealed film, the corrosion current density and corrosion rate decreased from 1.24 × 10−9 A/cm2 and 1.47 × 10−5 mm/a to 7.78 × 10−10 A/cm2 and 9.15 × 10−6 mm/a, respectively. Moreover, the average friction coefficient of the sealed film was 0.606, which was ~19.3% lower than that of the substrate and 3.3% lower than for the unsealed film.
The state of Florida's estuaries and future needs in estuarine research: Part 2. an academic research agenda (review draft)

As a program supporting academic research that addresses recognized societal needs, the Florida Sea Grant Program is developing a research theme area on estuaries to provide a uniquely academic product that will augment mission-oriented research undertaken by government and by the private sector. This report is not a call for proposals. It does not prescribe a specific research plan. Rather, it is a concept paper designed to focus research on two broad "organizing themes": (1) the hydrology of Florida's estuaries, and (2) the impact of cyclic environmental variability on estuarine function. (46pp.)
Endothelial Dysfunction in SARS-CoV-2 Infection

One of the hallmarks of the SARS-CoV-2 infection has been the inflammatory process that played a role in its pathogenesis, resulting in mortality within susceptible individuals. This uncontrolled inflammatory process leads to severe systemic symptoms via multiple pathways; however, the role of endothelial dysfunction and thrombosis have not been truly explored. This review aims to highlight the pathogenic mechanisms of these inflammatory triggers leading to thrombogenic complications. There are direct and indirect pathogenic pathways of the infection that are examined in detail. We also describe the case of carotid artery thrombosis in a patient following SARS-CoV-2 infection while reviewing the literature on the role of ACE2, the endothelium, and the different mechanisms by which SARS-CoV-2 may manifest both acutely and chronically. We also highlight differences from the other coronaviruses that have made this infection a pandemic with similarities to the influenza virus.
A systematic literature review and meta-analysis of the effect of psilocybin and methylenedioxymethamphetamine on mental, behavioural or developmental disorders

Objectives: There is an increasing interest in combining psilocybin or methylenedioxymethamphetamine with psychological support in treating psychiatric disorders. Although there have been several recent systematic reviews, study and participant numbers have been limited, and the field is rapidly evolving with the publication of more studies. We therefore conducted a systematic review of PubMed, MEDLINE, PsycINFO, the Cochrane Central Register of Controlled Trials, Embase, and CINAHL for randomised controlled trials of methylenedioxymethamphetamine and psilocybin with either inactive or active controls. Methods: Outcomes were psychiatric symptoms measured by standardised, validated and internationally recognised instruments at least 2 weeks following drug administration, Quality was independently assessed using the Cochrane risk of bias assessment tool and Grading of Recommendations Assessment, Development and Evaluation framework. Results: There were eight studies on methylenedioxymethamphetamine and six on psilocybin. Diagnoses included post-traumatic stress disorder, long-standing/treatment-resistant depression, obsessive-compulsive disorder, social anxiety in adults with autism, and anxiety or depression in life-threatening disease. The most information and strongest association was for the change in methylenedioxymethamphetamine scores compared to active controls in post-traumatic stress disorder (k = 4; standardised mean difference = −0.86; 95% confidence interval = [−1.23, −0.50]; p < 0.0001). There were also small benefits for social anxiety in adults with autism. Psilocybin was superior to wait-list but not niacin (active control) in life-threatening disease anxiety or depression. It was equally as effective as escitalopram in long-standing depression for the primary study outcome and superior for most of the secondary outcomes in analyses uncorrected for multiple comparisons. Both agents were well tolerated in supervised trials. Trial quality varied with only small proportions of potential participants included in the randomised phase. Overall certainty of evidence was low or very low using the Grading of Recommendations Assessment, Development and Evaluation framework. Conclusion: Methylenedioxymethamphetamine and psilocybin may show promise in highly selected populations when administered in closely supervised settings and with intensive support.
Osmotic Stress Interferes with DNA Damage Response and H2AX Phosphorylation in Human Keratinocytes

The human skin and in particular its outermost layer, the epidermis, protects the body from potentially harmful substances, radiation as well as excessive water loss. However, the interference between the various stress responses of the epidermal keratinocytes, which often occur simultaneously, is largely unknown. The focus of this study was to investigate the interference between osmotic stress and DNA damage response. In addition to revealing the already well-described regulation of diverse gene sets, for example, cellular processes such as transcription, translation, and metabolic pathways (e.g., the KEGG citrate cycle and Reactome G2/M checkpoints), gene expression analysis of osmotically stressed keratinocytes revealed an influence on the transcription of genes also related to UV-induced DNA damage response. A gene network regulating the H2AX phosphorylation was identified to be regulated by osmotic stress. To analyze and test the interference between osmotic stress and DNA damage response, which can be triggered by UV stress on the one hand and oxidative stress on the other, in more detail, primary human keratinocytes were cultured under osmotic stress conditions and subsequently exposed to UV light and H2O2, respectively. γH2AX measurements revealed lower γH2AX levels in cells previously cultured under osmotic stress conditions.