Miracle-dz/UniFAR-FTUs huggingface dataset:
Time Labeled Visibility Graph for Privacy-Preserved Physiological Time Series Classification

With the development of artificial intelligence (AI) and the continuous improvement of medical informatization, health assessment and auxiliary diagnosis based on physiological time series has become a hot research topic. However, the direct use of raw time series data is inappropriate due to privacy protection regulations in medial scenarios. Therefore, we designed a privacy-preserved framework based on Visibility Graph (VG) transformation and Graph Neural Network (GNN) for physiological data multi-classification. In particular, we proposed a Time Labeled Visibility Graph (TLVG), which uses the idea of VG to protect privacy while retaining more information that is useful for classification. Experiments are conducted based on the ECG5000 electrocardiogram dataset of the UCR time series classification archive. The comparison with existing classic and transformation-based classifiers shows the effectiveness and stable performance of our proposed method, providing an alternative and reasonable way for diseases diagnosis decision supports. Furthermore, from this research, it is discovered that the time sequence of each node in VG is an important feature in time series classification tasks.
The bioactive compounds content and antioxidant activities of some plant parts formulae distributed in Egyptian local markets

: Plant parts are important source of bioactive compounds and have been used for folk medicine for many centuries. The present study aimed to determine the bioactive compounds and antioxidant activities of some plant parts formulae distributed in the Egyptian local markets. Also, the potential effect of the tested formulae as a promising tool in the prevention of cardiovascular diseases (CVD) including atherosclerosis will be in the scope of this investigation. The results showed that selected formulae possessed stronger antioxidant properties in inhibiting both lipid peroxidation (  -carotene bleaching assay) and CuSO4-induced LDL oxidation. The tested formulae showed slightly differences in antioxidant activity (AA= 92.74-94.56%). The high antioxidant properties of the tested formulae appeared to be attributed to its high bioactive compounds in particular phenolics content were 2275 and 38484 mg.100g -1 for formula I and II, respectively. The values of two tested formulae absorbances throught 120 min are coming well i.e. closing the line of 50 mg α-tocopherol and up to the line of 50 mg /L of butyhydroxy toluene (BHT). When all selected formulae were included in the statistical analysis, there was a positive and highly significant (r 2 = 0.9179 - 0.9462, p< 0.05) relationship between total phenolics and antioxidant activity. Finally, the tested formulae could be used successfully as a promising tool in the prevention of atherosclerosis by inhibiting LDL oxidation which merits further intensive studies
FY05 LDRD Final ReportThe Innermost Inner Core: Fact or Artifact?LDRD Project Tracking Code 04-FS-019

P’P’ (PKPPKP) are P waves that travel from a hypocenter through the Earth's core, reflect from the free surface and travel back through the core to a recording station on the surface. Here we report the observations of hitherto unobserved near-podal P’P’ waves (at epicentral distance < 10º) and very prominent precursors preceding the main energy by as much as 60 s. We interpret these precursors as a back-scattered energy from previously undocumented horizontally connected small-scale heterogeneity in the upper mantle beneath the oceans in a zone between 150 and 220 km depth beneath the Earth’s surface. From these observations, we identify a frequency dependence of attenuation quality factor Q in the lithosphere through forward modeling of the observed amplitude spectra of the main and back-scattered P’P’ waves. In addition, we did not find that travel times corresponding to very polar paths through the centermost inner core with respect to the rotation axis of Earth are anomalously advanced, which argues for isotropic or at best – weakly-anisotropic center of Earth in the direction parallel with the rotation axis. More systematic sampling near Earth’s center and characterization of anisotropy in Earth’s center will be a subject of future research efforts.
The role of human biological monitoring in health risk assessment

Human biological monitoring refers to the measurement of biomarkers in biological specimens. Advances in analytical chemistry together with an increased understanding of the potential toxicity of environmental chemicals have propelled the quest to identify and monitor chemicals and metabolites in human biological specimens. Many biomonitoring programs have provided valuable data on the presence of environmental chemicals in biological matrices. The availability of this large volume of biomonitoring data has increased the need to understand this information with respect to potential human health risks. This review summarises approaches for interpreting biomonitoring data in the context of population health and risk assessment. Moreover, the advantages and limitations of human biomonitoring approaches, major challenges in the interpretation of HBM data and the utility of human biomonitoring data in health risk assessment context are presented. Several knowledge gaps to improve the ability to interpret human biomonitoring data are discussed.
Design and control of a hummingbird-size flapping wing micro aerial vehicle

Zhang, Jian. PhD, Purdue University, December 2015. Design and Control of a Hummingbird-Size Flapping Wing Micro Aerial Vehicle. Major Professor: Xinyan Deng, School of Mechanical Engineering. Flying animals with flapping wings may best exemplify the astonishing ability of natural selection on design optimization. They evince extraordinary prowess to control their flight, while demonstrating rich repertoire of agile maneuvers. They remain surprisingly stable during hover and can make sharp turns in a split second. Characterized by high-frequency flapping wing motion, unsteady aerodynamics, and the ability to hover and perform fast maneuvers, insect-like flapping flight presents an extraordinary aerial locomotion strategy perfected at small size scales. Flapping Wing Micro Aerial Vehicles (FWMAVs) hold great promise in bridging the performance gap between engineered flying vehicles and their natural counterparts. They are perfect candidates for potential applications such as fast response robots in search and rescue, environmental friendly agents in precision agriculture, surveillance and intelligence gathering MAVs, and miniature nodes in sensor networks. Designing and developing such systems is a challenging problem under stringent constraints in size, weight and power (SWaP). In addition, the lagging in battery technology, requirement on miniature sensors and actuators for navigation, limited on-board computational power, and system integration all pose challenges in design. Under the SWaP constraints, balance and trade-off must be made among mechanical complexity, controllability, power, and weight. Otherwise, even producing enough lift to sustain the weight can be a challenge. In this thesis, we present a systematic approach of vehicle design and optimization, resonance design, and flight control. Achieving resonance in flapping wings has been recognized as one of the most important principles to enhance power efficiency, lift generation, and flight control
SYRINGE-ASSISTED POINT-OF-CARE PUMPING

This paper presents a convient pumping method by only employing a hand held syringe. Due to the gas permeability of polydimethylsiloxane (PDMS), air trapped in the flow channel can be diffused into the surrounding vacuumed chammbers through the PDMS gaps between them. Thus after loading sample liquids, a constant flow was realized, whose flow rate can be controlled by the gap distance and overlap area between a dead-end channel and a surrounded chamber of the PDMS devices. Moreover, in order to realize a point-of-care application, the surrounded chamber was vacuumed by a hand-held syring. Therefore by pulling a syring only by hand, a constant flow rate ranging from 0.3 nl s -1 to 4 nl s -1 was realized in our experiment.
Hatching seeds before they’re counted Graphical methods for interpreting archaeobotanical data

Like other analytic aspects of archaeology, archaeobotany has been growing progressively more quantitative in the past few decades. This may be a sign of the proliferation of increasingly mature and sophisticated methodologies for analyzing botanical data, but associated with the sophistication of quantitative methods is their inherent opacity: the value and ap-plicability of anthropological conclusions drawn from quantitative archaeobotanical data are not only limited by the amount of information that can be extracted from data by sophisticated statistical tools, but also by our ability to draw reasonable anthropological— as opposed to merely statistical—conclusions. Even the words “classiﬁcation” and “signiﬁcance” have different meanings in statistics and in anthropology. In this paper, I propose the use of graphical analysis for archaeobotanical data in addition to, or instead of, typical statistical tools like signiﬁcance tests, variable reduction, and clustering. Applied to data from charred seed assemblages from the ancient Near East, the visual representation of quantitative data has the advantage of handling semiquantitative data better and being interpretable without reliance on the paradigm of a formal statistical test.
Depression is associated with hyperconnectivity of an introspective socio-a ﬀ ective network during the recall of formative relationship episodes

A B S Background: Depression and the experience of early adversity are associated with impairments in interpersonal and social cognitive functioning. The neural mechanisms involved in these impairments remain insu ﬃ ciently understood. Methods: In a sample of 48 depressed and 50 healthy participants, we explored seed-to-voxel functional connectivity (FC) during the recall of formative relationship episodes using functional magnetic resonance imaging. Results: While depressive symptoms were associated with increased FC of brain regions that form an introspective socio-a ﬀ ective network, such as the precuneus, bilateral anterior insula, dorsal anterior cingulate cortex, left amygdala, and medial prefrontal cortex, early adversity linked to decreased FC of brain regions mediating emotion processing such as the bilateral anterior insula and increased FC of the bilateral para- hippocampal gyrus. Limitations: We report both results that are corrected for the number of seeds tested in FC analyses using strict Bonferroni adjustments and unadjusted results as part of an exploratory analysis. Discussion: Our ﬁ ndings suggest that depression and early adversity are associated with di ﬀ erential FC patterns in the brain during the recall of formative relationship episodes. Hyperconnectivity of an introspective socio-a ﬀ ective network associated with depressive symptoms may link to enhanced self-focus and emotional re- activity. Patterns of neural activation associated with early adversity may underpin numbed a ﬀ ective states or enhanced a ﬀ ective memory regulation. Overall, these ﬁ ndings inform about the neural underpinnings of a re- ﬂ ective ability that is predictive of the adaptation to depression and to early adversity and relevant for psychotherapy outcomes.
DESIGN OF EH ANTENNA AS NEW POSIBLE TYPE OF AIRCRAFT ANTENNAS

The aim of the article is a technical analysis of this new type of antennas. From theoretical background are obvious real benefits of this type of antenna. This article describes theoretical elements of EH antenna, prototyping of EH antenna and real measurements in anechoic chamber. Results are visualised in graphs. Conclusion of article compares two types of antennas: linear and EH. Results are supported by measurements.
Polychlorinated biphenyls (PCBs) and their hydroxylated metabolites (OH-PCBs) in harbor seal () livers from San Francisco Bay, California and Gulf of Maine

23 Bioaccumulation of positioned top 24 the food chain is of toxicological concern. Stranded four pup and ten adult harbor seal 25 ( Phoca vitulina ) livers were collected from San Francisco Bay and the Gulf of Maine and 26 analyzed for polychlorinated biphenyls (PCBs) and their hydroxylated metabolites (OH- 27 PCBs). We used GC-ECD and GC-NCI/MS to investigate the presence of 28 PCBs and 28 8 OH-PCB metabolites, respectively. (cid:1) 28 PCB concentrations (di- to octa-CBs) ranged 29 from 1.81 to 35.9 m g/g lipid with a median of 6.53 for the seal pups and 2.31 to 249 m g/g 30 lipid with a median of 28.9 for the adult seals. (cid:1) 8 OH-PCB concentrations (penta- to 31 hepta-OH-PCBs) ranged from 0.02 to 0.69 m g/g lipid with a median of 0.04 for the adult 32 seals, i.e., at much lower concentrations than those for PCBs. Ratios of OH-PCBs to 33 PCBs (0.24% on average) were comparable to those in beluga whale, but were lower than 34 ratios in human livers. The OH-PCB profiles were slightly different between SFB and 35 GOM seal livers although similar PCB congener patterns were observed. Generally, 4- 36 OH-CB107 was found predominantly in seal livers and was the only OH-PCB detectable 37 in most of seal pup livers. This study provides information on OH-PCBs in seals, adding 38 to the scarce exposure data for these chemicals.
A framework proposal for harvesting service parts at Philips Health Tech

Reverse Logistics (RL) has become a field of importance for all organizations due to growing environmental concerns, social responsibility and sustainable competitiveness. One of the activities of RL is the reuse of parts or products into other processes. This activity, like many others, needs the support of Information Technology (IT) in order to be enabled. IT has become a vital part of today’s business environment. Almost all companies rely on computers and software to provide accurate information in order to effectively manage their business. The role of IT is crucial also for managing reverse logistics. Because RL processes span multiple functional areas, such as materials, finance, sales etc., an integrated information system solution is required. SAP Enterprise Resource Planning (ERP) systems provide a potential solution by integrating all facets of the business. However, these systems create high dependency among the shared users of the system. Implementing a reuse process in one of the participants of the system can have a great impact on the working ways of the others. To limit this impact it is necessary to align between all the involved stakeholders in the reverse supply chain. The current literature lacks a well-structured approach for implementing a reuse process flow in an existing SAP interface, while considering the impact on the other participants of the system. In this master thesis, we address this research gap by designing a comprehensive approach for setting up a reverse logistics activity in a servicing organization. We investigate options for enabling and supporting the process through SAP, and offer a thorough impact assessment to the other actors in the supply chain. In order to investigate requirements and solutions, both technical and business aspects of the problem are considered. The result of this project is a comprehensive approach which provides all the involved stakeholders with an efficient and practical solution for managing a reuse process.
Integration of production scheduling and delivery in two echelon supply chain

ABSTRACTFor a production scheduling and delivery problem, there are multi-products processed by a distribution centre and then delivered to retailers. The resolution of the problem is to determine the production sequence, retailers' needs to heterogeneous fleet of vehicles and the visiting sequence of each vehicle within time windows. In this article, the problem is considered with minimising the total cost which includes delivery cost, fixed vehicle cost, and penalty cost, subjected to satisfy all demands of each retailer. The adaptive genetic algorithms (AGAs) are designed and tested in variety of production and delivery scenarios. The computational experiments show that backward-AGA (B-AGA) has distinguished performance between two AGAs. However, F-AGA has better solving efficiency when N ⩾ 50 and the solving performance is fairly similar subjected to the geographical group R and N ⩾ 50. In addition, the experiments indicate that combined with more vehicle types in delivery stage is not only reduced th.
Effect of Intravenous Vitamin C on Urine Neutrophil Gelatinase-Associated Lipocalin Among Septic Patients: Randomized Controlled Trial

Background The role of vitamin C to decrease organ dysfunction in sepsis was still controversial. This study aimed to explore the effect of intravenous (IV) vitamin C on urine NGAL (uNGAL) levels among septic patients in ICU. Methods This study was a randomized clinical trial held in Cipto Mangunkusumo Hospital from April to July 2019 with consecutive sampling method. Patients aged > 18 years with sepsis based on the criteria of sepsis-3 who were admitted to the ICU were included in this study. Exclusion criteria were those with chronic kidney problems, with kidney stones, undergo renal replacement therapy in the ICU. All subjects were divided into: Group A was treated with combination of vitamin C and thiamine while Group B was given thiamine only. The uNGAL level was measured at baseline, 24, 48 and 72 h after treatment. Anova for repeated measurement using General Linear Model for Repeated Measurement was used with level of significant at p-value <0.05. Results Total of 33 subjects were included. In Group A we found uNGAL (ng/ mL) were 74.5 (13.3-102.9), 77.3 (15.298.4), 67.2 (22.6-100.6), 77.2 (17.0-100.5) for baseline, 24 h, 48 h, and 72 h respectively. While in Group B uNGAL were 57.7 (11.5-94.5), 57.1 (6.4-97.7), 53.7 (13.3-99.6), 47.6 (4.5-100.9). No significant difference in terms of uNGAL between two groups at each hour was found. Conclusions This study showed that intravenous vitamin C administration had no effect on uNGAL among septic patients. Need more study to investigate approaches to improve kidney and inflammatory biomarker among septic patients.
Network governance for dealing with IT-enabled Interorganizational cooperation

IT-based networking trends such as the rise of social media, crowd sourcing, open innovation, and cloud computing enable a profoundly different way of working and collaborating that challenges significantly traditional approaches of companies towards governance, i.e. the mechanisms a company employs to achieving business results and safeguarding information. Standard practices developed with a hierarchical model of the company in mind, are inadequate for providing sufficient correlation between governance mechanisms deployed and results achieved. Popular literature on the subject states that dealing effectively with such new technologies in a business environment requires relinquishing control and subverting to trust. This paper makes the case that deploying successfully new IT-based networking tools rather involves shifting one’s trust from a well-established and well-known governance system based on hierarchy and control towards another governance system, termed in the literature as network governance. This paper assesses when network governance is the better suited governance system. The presented theoretical model helps to understand how companies should use arising new technologies and which tasks are suited for network-driven IT-applications. Furthermore, the model enables to understand how network governance works to achieve business results and to safeguard information exchanges.
The Growth Factor-like Effects of Tumor Necrosis Factor-a! STIMULATION OF GLUCOSE TRANSPORT ACTIVITY AND INDUCTION OF GLUCOSE TRANSPORTER AND IMMEDIATE EARLY GENE EXPRESSION IN

In the present the ability necrosis factor-a (TNF) to stimulate hexose in The entire study presented was performed using recombinant human TNF-n, rather than murine TNF as stated under “Experimental Procedures. ” In experiments where we were able to compare human versus murine TNF, the results were identical. The specific activity, as well as levels of endotoxin contamination, are
Sustaianable development and environmental policy: the engagement of stakeholders in green products in Vietnam

Facing the challenge of environmental degradation in Vietnam, a growing number of firms have begun to integrate environmental management systems into their business strategies and develop green product diversification strategies. Based on the stakeholder theory, this paper attempts to explore the influences of stakeholders on the implementation of horizontal and vertical green product diversification. Empirical results show that foreign customers play a significant role in driving companies to adopt strategy of green product diversification. For foreign-invested enterprises, the effect is limited to the adoption of horizontal green product diversification. It further reveals thatInstitutional weakness, lack of transparency, community stakeholders and regulatory stakeholders have no significant effect on the corporate green product strategy.
The transformation of isolated gastric myeloid sarcoma into acute myeloid leukemia presenting with a complex karyotype and TLS-ERG gene fusion

Abstract Rationale: Isolated myeloid sarcoma (MS) is characterized by the rapid proliferation of myeloblasts of acute myeloid leukemia (AML), without any blood or bone marrow involvement. This disease can manifest with extramedullary organ involvement, such as the skin, lymph nodes, bone, brain, breast cervix, and visceral organs, while the occurrence of myeloid sarcomas in the stomach is rare. Isolated MS has been associated with acute myeloid leukemia (AML), but the rapid progression of MS to acute myeloid leukemia with a complex karyotype and TLS-ERG fusion gene is even rarer. Patient concerns: A 33-year-old woman suffered from persistent epigastric pain accompanied by two months of anorexia and nausea, as well as 1-week of melena. Diagnosis: This patient was initially diagnosed with gastric MS that eventually transformed into AML with a complex karyotype and TLS-ERG fusion gene, 4 months later. Interventions: Only palliative care, including nutrition support, antacids, blood transfusion, anti-infection methods were used on this patient to determine the cachexia status and the family's requirement. Outcomes: Routine follow-up results demonstrated this patient had died due to cerebral hemorrhage five months after the diagnosis of MS. Lessons: Comprehensive integration of patient history, imaging features, mass and bone marrow biopsy, and molecular cytogenetic may provide insights that could help us avoid the misdiagnosis of gastric MS. Isolated gastric MS can rapidly progress to AML with a poor prognosis if the patient does not receive appropriate treatment.
T staging with functional and radiomics parameters of computed tomography in colorectal cancer patients

Abstract Preoperative T staging is closely related to operation planning and prognosis of colorectal cancer (CRC). This study aimed to re-investigate the value of computed tomography (CT) in T stage evaluation of CRC patients with both functional and radiomics parameters. The functional and radiomics parameters of CT images and the clinical information were collected from 32 CRC patients. The radiomics parameters were measured based on manually labelled 5-mm circles using software Syngo. The radiomics parameters were computed based on labelled tumor regions using Python software package. A total of 125 parameters were collected and analyzed by using decision tree analysis. The decision tree analysis identified 6 rules. Based on the rules, the shape elongation, flow extraction of nodule and blood volume of tumor region were found to be of significance and could define a high-risk group and a low-risk group. This study shows the combination of functional parameters and radiomics parameters of CT is helpful for the diagnosis and T staging of CRC.