Miracle-dz/UniFAR-FTUs huggingface dataset:
The value of trade credit with rebate contract in a capital-constrained supply chain

We investigate the value of an innovative trade credit with rebate contract (TCRC) model in a stylised supply chain. In this supply chain, the capital-abundant manufacturer offers an integrated contract involving trade credit, minimum ordering and sales rebate contract to a capital-constrained retailer. To highlight the value of the TCRC model, we compare it with a traditional trade credit financing (TTCF) model in a ‘selling to the newsvendor model’. First, we show that equilibrium strategies exist between the manufacturer and the retailer under the TCRC or TTCF model. Second, this study investigates equilibrium selection between the TCRC and TTCF models for the individual and the supply chain. Finally, we show the manufacturer’s pricing policy, wherein the TCRC model outperforms the TTCF model for the players. Furthermore, we conduct a set of numerical experiments to show evidence for theoretical analysis and measure the operation efficiency of the TCRC model for players in the supply chain.
Introduction of the hypocholesterolemic peptide, LPYPR, to the major storage protein of mung bean [ Vigna radiata through site-directed mutagenesis

The hypocholesterolemic peptide, LPYPR, was successfully introduced into the VR-1, VR-2, and VR-5 regions of the mung bean 8Sα globulin. The mutant protein (MP) has 96.69% structural homology and 97% sequence homology compared to the wild type (WT). Expression of the mutant protein in E. coli HMS174(DE3) was 40.66%, which was 144.42% higher than that of the WT. The WT protein and MP had MWs of about 48.4 and 48.7 kDa, respectively. These were purified using HIC and digested with trypsin. UPLC analysis of the tryptic digests of the MP revealed the successful release of the LPYPR peptide. Unlike the WT protein, cholesterol-binding capacity (mg/g sample) of the MP increased over time of tryptic digestion (average growth rate of 9.5% for crude MP and 12.5% for HIC-purified MP) for its undigested form (crude: 220.96 ± 8.65, purified: 214.71 ± 11.91), with maximum values of 380.76 ± 6.61 and 434.44 ± 10.88 were obtained for the 24-h digests of the crude and purified proteins, respectively. Similarly, the sodium taurocholate binding capacity (%) was also found to increase over time of tryptic digestion (average growth rate of 4% for crude MP and 5.67% for HIC-purified MP) for the tryptic digests of the MP. Minimum values for % bound sodium taurocholate was obtained with the undigested samples (crude: 46.71 ± 0.42, purified: 44.49 ± 0.13), while maximum values thereof were obtained with the 24-h digest samples (crude: 59.75 ± 0.30, purified 61.95 ± 0.51). mutagenesis,
Designing Social Question-and-Answering Interaction Using Goal-Directed Design Method

A social question-and-answering (social Q&A) site is an online community where users can ask and answer questions to share their knowledge and all data are publicly accessible. The platform has caught its users’ attention and given them a new way in getting information from other users. However, the growth of social Q&A sites is still followed by some problems faced by its users. This study aims to develop an interaction design of social Q&A using goal-directed design (GDD) method. Compared to User-Centered Design method, the GDD has more specific process. The process accomplished in the development includes four phases: research, modeling, requirement definition, and framework definition. The research phase was done by conducting literature review and potential user interview. The modeling phase was carried out to explore behavior patterns, and combine them into user model. The requirement definition was conducted to determine product functionality and design. In this phase, user scenarios that describe how a persona uses the product were developed. The framework definition phase focused on an interaction framework which was conducted through six steps. The series of phases resulted in personas, scenarios, requirements, and wireframes of the product. Social Q&A product developed in the study is one that is specialized for asking and sharing information about studying abroad. The design was developed in the form of product wireframes and key path scenarios along with storyboards that describe interaction in the product. Key path scenarios were constructed based on tasks personas could perform in the product. Further works include developing visual design framework and conducting usability testing of the design to potential users.
Accelerating the computation of the volume of tissue activated during deep brain stimulation using Gaussian processes

The volume of tissue activated (VTA) is a well-established approach to model the direct effect of deep brain stimulation (DBS) on neural tissue. Previous studies have pointed to its potential clinical applications. However, the elevated computational runtime required to estimate the VTA with standard techniques used in biological neural modeling limits its suitability for practical use. The goal of this study was to develop a novel methodology to reduce the computation time of VTA estimation. To that end, we built a Gaussian process emulator. It combines multicompartment axon models coupled to the stimulating electric field with a Gaussian process classifier (GPC), following the premise that computing the VTA from a field of axons is in essence a binary classification problem. We achieved a considerable reduction in the average time required to estimate the VTA, under both ideal isotropic and realistic anisotropic brain tissue conductive conditions, limiting the loss of accuracy and overcoming other drawbacks entailed by alternative methods.
Causal Relationship between Macroeconomic Factors and Stock Prices in Pakistan

: The research paper aims to investigate the significant macro-economic factors affecting the stock Prices of KSE-100 Index. Time series Data for Stock Prices on monthly basis for the period ranging January, 2005 to March, 2014 has been taken from KSE-100 Index. The study used time series data analysis. Sample comprises of 30 companies from KSE-100 Index for analysis. Macro-economic variables selected in the study are Inflation (CPI), Producer Price Index (PPI), Gold price, Silver price, Exports and Imports. Augmented Dickey Fuller test has been used to check stationarity of data, Johansen’s Cointegration test and Ganger’s causality tests has been used to measure the causal relationship between stock prices and selected macro-economic variables. The results suggested that stock prices are cointegrated with macro-economic variables in long term. Furthermore, macroeconomic variables Inflation, PPI, Gold price and Exports have long term causal relationship with stock prices in Pakistan.
CorrelatioN of well-beiNg witH resilieNCe aND age

Resilience and positive thinking, resilience and optimism, kindness as value could be the factors which could impact the future of our humanity and Earth as well as health and welfare of society. There is an active process of research in the positive psychology carried out in Latvia within the last ten years. The most important category of positive psychology is resilience and well-being. A lot of work has been done regarding adaptation of the concept of well-being and resilience in Latvia. There is a group of young researchers (master level students) who have made a contribution to adaptation of the concept of resilience and well-being in the science of psychology in Latvia at Riga Teacher Training and Education Management Academy (RTTEMA). A group of professors have recently made a joint research, where different samples of adults are demonstrated among the Latvian population in this article. The idea of this research is to analyse the collected secondary data on different groups of adults concerning correlation between the aspects of well-being and resilience. The aim of the research is to investigate the dimension of well-being in cognitive, eudaimonistic, hedonistic, interpersonal and spiritual (transcendent) relationship with resilience indicators - self-perseverance, self-reliance, acceptance of life, as well as the relevance of well-being indicators to age. One statement of this analysis was the hypothesis about the age as a factor which predetermines de velopment of well-being and resilience. of men (N=351, which was made using the secondary data of three studies (Majors & Majore, 2009; Madžule, 2013; Tauriņa, 2013). It was found out, that the indicators of well-being have a direct and a rather close correlation with the indi cators of resilience which provided the answer to the research question, what kind of correlation between the indicators of well-being and resilience exists. The indicators of the well-being dimension indicators have a little or rather close correlation with the parameters of the resilience dimension(0.29<r<0.58). It was found out, that well-being is more predicted by self-reliance of the resilience indicator, which provided the answer to the research question, which well-being indicators predict these resilience indicators. It was found out, that the dimensions of well-being do not correlate with age group in the statistical sense, but only some subdimensions of the purposefulness of well-being in life, perception and transcendence correlate with age at the trend level, providing the answer to the research question, whether there is a correlation between the age and well-being, resilience and age group.
2001 International Student Paper Award Winner

Professional culture is important to guide members of a profession to think and behave as the profession requires. Project management (PM), as a new profession, should have its own professional culture, which could be minimally defined as a set of work-related values and beliefs shared by PM professionals. On the basis of a questionnaire survey, this research used exploratory and confirmatory factor analyses to establish a model of PM culture consisting of four key dimensions: professional commitment, project team integration, work flexibility, and viewing others in terms of work performance. For each of the dimensions, two or three subdimensions were identified. Also, PM professionals’ current values and beliefs around the dimensions and subdimensions were explored using descriptive and t-test statistics to reveal some potential for improvement of the profession.
Factors Affecting Prosocial Sharing Health-related Information on Social Media During a Health Crisis

During a health crisis, prosocial sharing of health-related information (HRI) on social media can help to deliver early warnings about new diseases, raise social awareness, exchange support, and spread health policies. Current literature has mainly focused on the factors of general sharing of HRI under normal conditions but neglected those motivations under the health crisis context. This research aims to investigate factors that influence online users’ prosocial sharing of HRI during a health crisis. To obtain the objective, this study developed a dual helping-protecting motivation model from the fear appeal model and social exchange theory. The partial least squares analysis, carried out on the surveyed data of 326 participants, revealed that Prosocial sharing is affected by protecting factors (i.e., sharing efficacy, response efficacy) and helping factors (i.e., reciprocity expectation). Additionally, both perceived health risk and perceived information quality risk were found to influence the sharing intention via motivational factors.
Standardised Ethanol Extract of Tithonia diversifolia (Hemsley) A Gray Leaves Improve Insulin Sensitivity and Increase Mitochondrial DNA Copy Numbers in Skeletal Muscles of Streptozotocin-Nicotinamide-Induced Rats

Background In this study, we examined the anti-diabetic activity of standardised extracts of Tithonia diversifolia (Hemsley) A Gray (T. diversifolia) leaves for their effects on insulin resistance and mitochondrial DNA (mtDNA) copy number. Methods T. diversifolia leaves were extracted using an ultrasound-assisted method and standardised using Tagitinin C. There were six groups: i) normal control; ii) diabetic group; iii) metformin group (300 mg/kg) and iv) groups treated with three different doses of extract (50 mg/kg, 100 mg/kg and 150 mg/kg). Blood samples were taken before and after 28 days of treatment for fasting plasma glucose (FPG) and insulin analysis, which were used for a Homeostatic Model Assessment for Insulin Resistance (HOMA-IR) calculation. The soleus and gastrocnemius muscles were harvested after 28 days of treatment for the measurement of mtDNA copy number. Results The results showed an improvement in blood glucose levels and HOMA-IR scores in all treatment groups. The results of mtDNA copy number analysis also revealed significant improvement with the highest number observed at an extract dose of 100 mg/kg in which the mtDNA copy number increased up to 3 times in the soleus muscles (P < 0.001). Conclusion T. diversifolia extract has the potential to be used as an anti-diabetic agent that improves insulin resistance, possibly by increasing mtDNA content.
finding the right

Since 2016, Solvency II has brought major changes to prudential supervision in the Union, by providing a harmonised and sound prudential regime for insurance companies. Its first pillar set out an entirely new, risk-based framework for the measurement of risks. This was complemented by qualitative and transparency requirements under the second and third pillars. The reform aligned prudential supervision more closely with state-of-theart risk management practices.
Cyber and Electromagnetic Threats in Modern Relay Protection

Cyber and Electromagnetic Threats in Modern Relay Protection provides a detailed overview of the vulnerabilities of digital protection relays to natural and intentional destructive impacts, including cyber attacks and electromagnetic intrusions. From lightning strikes, electromagnetic elds generated by operating equipment, and issues with control cable shielding to modern technical tools that realize intentional destructive impacts remotely, this rst-of-its-kind text covers the latest cyber and electromagnetic threats to digital protection relays.
17-Year Changes in Body Mass Index, Waist Circumference, Elevated Blood Pressure, and Diabetes Phenotypes in a Cohort of Filipino Women

, Abstract Obesity, hypertension, and diabetes have risen dramatically in Asia, but few cohort studies track age and secular trends in these conditions. We use Cebu (Philippines) Longitudinal Health and Nutrition survey data to document 1998–2015 prevalence and co-occurrence of BMI>25 kg/m 2 , high waist circumference (WC>80 cm), elevated blood pressure (EBP, systolic >=130 or diastolic>=85 mm Hg), and type 2 diabetes among ~2000 women ages 29–62 1998; and identify their relationship to community, household, and individual factors using longitudinal logistic regression. Prevalence (1998–2015) rates were: 35–49%, BMI>25 kg/m 2 ; 32–58% high WC; 21– 59% EBP; 2–14% diabetes. Only 20% of women had none of these conditions in 2015. Diabetes was strongly driven by age and secular trends in high WC related to higher SES and urbanization. Hypertension increased with age in lower SES rural, and more affluent urban women. Results underscore the continuing need for public health measures to prevent obesity and to identify and treat hypertension and diabetes.
Simulation studies on the detection efficiency for a phoswich detector with background rejection capability

Simulation studies were performed on calculation of the detection efficiency for a phoswich detector with background rejection capability for continuous blood sampling system. The detector consists of a plastic scintillator, a BGO scintillator, and a photomultiplier tube (PMT). The pulse shape information is used to distinguish whether the detected event is a true event or a background one. First, we calculated the transmission efficiency of the positron in the tube. And we calculated the detection efficiency of positrons detected by the plastic scintillator. We also calculated the detection efficiency of 511 keV gamma photons by the BGO.
in a in

Agricultural management and the landscape surrounding farms impact biological diversity and ecosystem services, such as predation, in agroecosystems. Diversi ﬁ ed coffee agroecosystems harbor biodiversity, and maintain ecosystem services, especially when in complex landscapes, and when diversity of organisms providing services is maintained. But few have examined whether biological diversity, per se, or the local and landscape habitat features are stronger drivers of the services provided. We studied the relationships between local characteristics associated with agricultural management (vegetation complexity and agrochemical use), landscape surroundings of farms, abundance and richness of ants, and predation services provided by ants in a tropical coffee landscape. Speci ﬁ cally, we tested whether: (1) ants remove prey items and prey removal differs in the wet and dry season, (2) ant prey removal differs in farms that vary in vegetation complexity and agrochemical use, (3) ant prey removal differs with changes in ant abundance and species richness, and (4) ant prey removal differs with changes in local and landscape characteristics. We established sites across a range of coffee management systems, at varying distances to forest fragments, and in forest fragments and examined prey removal by ants on the ground, coffee branches, and shade tree trunks in the wet and dry season. Prey removal did not differ with season. Prey removal on the ground increased within increases in ant abundance and richness, and number of hollow coffee twigs. Prey removal on coffee plants decreased with vegetation complexity, but increased with ant abundance and richness, coffee density (a local factor), and rustic coffee within 200 m (a landscape factor). Prey removal on trees declined with vegetation complexity, but increased with abundance and richness of ants. Characteristics of the ant community were consistent predictors of prey removal, whereas local and landscape habitat features were less important, and only three habitat features correlated with prey removal. Our results demonstrate the positive effects of ant diversity for predatory function, and that promoting pest control services within coffee agroecosystems may be best accomplished by manipulating ant abundance and richness, or vegetation factors that correlate with ants.
Implementation of a Single-Phase SST for the Interface between a 13.2 kV MVAC Network and a 750 V Bipolar DC Distribution

This paper presents the implementation of a single-phase solid-state transformer (SST) for the interface between a 13.2 kV medium voltage alternative current (MVAC) network and a 750 V bipolar DC distribution. The SST has ten cascaded subunits in consideration of the device rating and modulation index (MI). Each subunit consists of an AC/DC stage and a DC/DC stage with a high frequency isolated transformer (HFIT). The AC/DC stage consists of cascaded H-bridges (CHBs) to cope with the MVAC. The DC/DC stage employs a triple active bridge (TAB) converter for bipolar DC distribution. Topology analysis and controller design for this specific structure are discussed. In addition, the insulation of HFIT used in DC/DC converters is also discussed. A simple balancing controller at the AC/DC stage and a current sharing controller at the DC/DC stage are used to prevent DC-link voltage unbalance caused by the cascaded structure. The discussions are validated using a 150 kW single-phase 21-level SST prototype at the laboratory level.
Interacting genomic landscapes of REC8-cohesin, chromatin 3 and meiotic recombination in Arabidopsis thaliana 4

Meiosis recombines genetic variation and influences eukaryote genome evolution. During meiosis, DNA double-strand breaks (DSBs) enter interhomolog repair to yield crossovers and non-crossovers. DSB repair occurs as replicated sister chromatids are 36 connected to a polymerized axis. Cohesin rings containing the REC8 kleisin subunit 37 bind sister chromatids and anchor chromosomes to the axis. Here we report the 38 genomic landscape of REC8 using ChIP-seq in Arabidopsis thaliana . REC8 associates 39 with regions of high nucleosome occupancy in multiple chromatin states, including 40 histone methylation at H3K4 (expressed genes), H3K27 (silent genes) and H3K9 41 (silent transposons). REC8 enrichment is associated with suppression of meiotic DSBs 42 and crossovers at the chromosome and fine scales. As REC8 enrichment is greatest in 43 transposon-dense heterochromatin, we repeated ChIP-seq in kyp suvh5 suvh6 44 H3K9me2 mutants. Surprisingly, REC8 enrichment is maintained in kyp suvh5 suvh6 45 heterochromatin and no defects in centromeric cohesion were observed. REC8 46 occupancy within genes anti-correlates with transcription and is reduced in COPIA 47 transposons that reactivate expression in kyp suvh5 suvh6 . Abnormal axis structures 48 form in rec8 that recruit DSB-associated protein foci and undergo synapsis, which is 49 followed by chromosome fragmentation. Therefore, REC8 occupancy correlates with 50 multiple chromatin states and is required to organize meiotic chromosome architecture 51 and interhomolog recombination. 52 REC8, foci repair foci interhomolog metaphase
Enhancement of Network Level Macrotexture Measurement Practices through Deterioration Modeling and Comparison of Measurement Devices for Integration into Pavement Management Systems

This research sought to integrate measurement and prediction of surface macrotexture for use in pavement management systems. This was achieved through two experiments, the first modeled the behavior of a binder-rich stone matrix asphalt when subjected to traffic loading using a heavy vehicle simulator to report the effect on pavement macrotexture. The second experiment compared high-speed macrotexture measurement devices on a variety of surfaces and under various operating conditions. The change in macrotexture due to traffic loading showed that as the cumulative load increased, the macrotexture decreased due to bleeding on the pavement’s surface. A regression model determined that, on average, the macrotexture’s root mean square (RMS) decreased 0.14 mm per million equivalent single axle load applied. A comparison of RMS and mean profile depth (MPD) outputs indicated that RMS was more sensitive to changes in macrotexture due to bleeding. In comparing devices, pairwise device agreement was evaluated using a Limits of Agreement. The results demonstrate good repeatability for each of the devices tested. The agreement analysis showed that not all highspeed devices can be used interchangeably for all pavement surfaces. Data acquisition speed was found to be a factor in macrotexture parameter calculation for two of the devices. The effect of speed was found to be worse on randomly textured surfaces than on transversely textured surfaces.