Miracle-dz/UniFAR-FTUs huggingface dataset:
Protocol of the China ST-segment elevation myocardial infarction (STEMI) Care Project (CSCAP): a 10-year project to improve quality of care by building up a regional STEMI care network

Introduction Successful ST-segment elevation myocardial infarction (STEMI) management is time-sensitive and is based on prompt reperfusion mainly to reduce patient mortality. It has evolved from a single hospital care to an integrated regional network approach over the last decades. This prospective study, named the China STEMI Care Project (CSCAP), aims to show how implementation of different types of integrated regional STEMI care networks can improve the reperfusion treatment rate, shorten the total duration of myocardial ischaemia and lead to mortality reduction step by step. Methods and analysis The CSCAP is a prospective, multicentre registry study of three phases. A total of 18 provinces, 4 municipalities and 2 autonomous regions in China were included. Patients who meet the third universal definition of myocardial infarction and the Chinese STEMI diagnosis and treatment guidelines are enrolled. Phase 1 (CSCAP-1) focuses on the in-hospital process optimisation of primary percutaneous coronary intervention (PPCI) hospitals, phase 2 (CSCAP-2) focuses on the PPCI hospital-based regional STEMI care network construction together with emergency medical services and adjacent non-PPCI hospitals, while phase 3 (CSCAP-3) focuses on the whole-city STEMI care network construction by promoting chest pain centre accreditation. Systematic data collection, key performance index assessment and subsequent improvement are implemented throughout the project to continuously improve the quality of STEMI care. Ethics and dissemination The study has been reviewed and approved by the Ethics Committee of Peking University First Hospital. Ranking reports of quality of care will be generated available to all participant affiliations. Results will be disseminated via peer-reviewed scientific journals and presentations at congresses. Trial registration number NCT03821012.
Dietary Diversity of an Adult Solomon Islands Population

Ongoing dietary transitions in the Solomon Islands has resulted in an over-reliance on commercially sourced foods, leading to food insecurity, and a subsequent rise in multiple forms of malnutrition. The aim of this study was to investigate the individual dietary diversity and food preferences of the adult population living in Auki, Solomon Islands. A cross-sectional study involving 133 adults was undertaken in the Auki district via an interviewer-administered questionnaire. Individual dietary diversity scores (DDS) were determined based on the results of a 24-h recall method. Overall mean DDS was 7.27 (range 2–12). Females and participants who lived outside the Auki town center had significantly higher dietary diversity scores. Low consumption of a variety of nutritious foods within food groups and high consumption of energy dense processed foods, indicates that diet quality is likely limited in some of this population. Participants desire for a diverse diet including local foods suggests that current dietary diversity status in this population may be influenced by food security rather than food preference.
Patient Attitudes About Viewing Their Radiology Images Online: Preintervention Survey

Background Although patient data is available through electronic portals, little information exists about the benefits and/or challenges of providing patients with online access to their radiology images. Objective The aims of this quality improvement project were to understand patient attitudes toward being able to view their radiology images online and determine how information should be presented to ensure the images are helpful to the patients, rather than causing confusion and anxiety. Methods An online survey of consumers was conducted to evaluate attitudes toward online access to personal radiological images. Results A total of 105 responses were received from 686 community members (15.3%). Of 105 consumers, 94 (89.5%) reported a desire to have access to the radiology images within their online patient portal; 86.7% (91/105) believed it would help them better understand their medical conditions and 81.0% (85/105) said this would help them feel more in control of their care. Most respondents (74/105, 70.5%) said it would help them feel reassured that their doctor was doing the right thing, and 63.8% (67/105) said it would increase their level of trust in their doctor. Among surveyed patients, 78.1% (82/105) valued viewing their radiology images online, while 92.4% (97/105) valued their online radiology reports. Most patients (69/105, 65.7%) wished to discuss their results with their ordering clinician, 29.5% (31/105) wished to discuss with their interpreting radiologist, and 3.8% (4/105) wished to share their images on social media. The biggest potential concern among 23.8% (25/105) was that the images would be confusing. Conclusions A large majority of surveyed patients desired the ability to view their radiology images online and anticipated many benefits and few risks. Health care organizations with electronic health records and online patient portals should consider augmenting their existing portals with this highly desired feature. To avoid the biggest patient concern, radiology reports should accompany images. Patients wanted to discuss their results with their ordering physician and their interpreting radiologist. Some even would like to share results on social media. Further research on the actual experience with such a tool will be needed.
Mobile Ad-hoc Network: Working of RoutingProtocols and Applications

Mobile Ad-Hoc Network (MANET) is a collectionof two or more devices or nodes or terminals with wireless communications and networking capability that communicate with each other without of any centralized administrator also the wireless that can dynamically form a network to exchange information without using any existing fixed network infrastructure. And it’s an autonomous system in which mobile hosts connected by wireless links are free to be dynamically and sometimes acts as a router at the same time. With some restriction of wired communication wireless technology comes into the picture. The emphasis in this paper is concentrated on Mobile Ad- Hoc Networks. They can be set up anywhere without any need for external infrastructure (like wires or base stations). This can be a standard Wi-Fi connection, or another medium, such as a cellular or satellite transmission [1]. This paper includes working of some Proactive, Reactive and Hybrid protocols that make communication possible it also includes its advantages, limitations and applications of MANET. Protocols discussed in this paper are DSR, AODV, TORA, FSR, ZRP, WPR etc.
Awareness and Collaboration Across Stakeholder Groups Important for eConsent Achieving Value-Driven Adoption

Background While the shift to digital technologies is pervasive across multiple industries, the informed consent process for clinical trials remains largely paper-based. Given the inefficiencies in the traditional process and the increasing complexity of clinical studies, the current approach at times may raise challenges with respect to quality, compliance, participant understanding, and trial retention. Electronic informed consent (eConsent) is an enabling clinical technology to potentially address these issues by using multimedia components to create an interactive participant experience and improve data quality. Methods The TransCelerate eConsent Initiative conducted a multifaceted engagement approach to better understand the perceptions, experiences, and concerns of impacted stakeholders, including participants, sites, ethics committees, and health authorities. Results While all stakeholders were supportive of the use of multimedia components to deliver study information, several stakeholder-specific concerns were noted. Participant feedback, as collected through surveys (n = 3045) and an advisory board (n = 10), suggests that some participants may have data privacy concerns and a diversity of preferences for multimedia presentation. Site interviews (n = 9) suggest concerns related to additional operational activities and potential for technology failure. Health authorities’ feedback, through nonbinding meetings, was geographically varied; ethics committee feedback, through interviews, suggests concern over impact on operational process changes. Conclusions While the appetite for eConsent is increasing, involved stakeholders and industry must continue to raise awareness, communicate, and collaborate to develop appropriate technological capabilities, regulatory pathways, and operational processes to clear the path for mainstream use of eConsent.
Does diversifying crop rotations suppress weeds? A meta-analysis

Over the past half-century, crop rotations have become increasingly simplified, with whole regions producing only one or two crops in succession. Simplification is problematic from a weed management perspective, because it results in weeds' repeated exposure to the same set of ecological and agronomic conditions. This can exacerbate weed infestations and promote the evolution of herbicide resistance. Diversifying crop rotations through addition of crop species and their associated managements may suppress weeds and reduce selection pressure for herbicide resistance by altering stress and mortality factors affecting weed dynamics. Here we report the results of a meta-analysis using 298 paired observations from 54 studies across six continents to compare weed responses due to simple and more diverse crop rotations. We found diversifying from simple rotations reduced weed density (49%), but did not have a significant effect on weed biomass. We investigated the effect of management practices, environmental factors, and rotation design on this effect. Diversification that increased the variance around crop planting dates was more effective in suppressing weeds than increasing crop species richness alone. Increasing rotational diversity reduced weed density more under zero-tillage conditions (65%) than tilled conditions (41%), and did so regardless of environmental context and auxiliary herbicide use. Our findings highlight the value of diversifying crop rotations to control weed populations, and support its efficacy under varied environmental conditions and management scenarios.
Conjugation of Dasatinib with MHI‐148 Has a Significant Advantageous Effect in Viability Assays for Glioblastoma Cells

We hypothesized that conjugation of the near‐infrared dye MHI‐148 with the anti‐leukemia drug dasatinib might produce a potential theranostic for glioblastoma. In fact, the conjugate was found to bind the kinases Src and Lyn, and to inhibit the viability of a glioblastoma cell line with significantly greater potency than dasatinib alone, MHI‐148 alone, or a mixture of dasatinib and MHI‐148 at the same concentration. It was also used to successfully image a subcutaneous glioblastoma tumor in vivo.
Multimodal Corpora : How should multimodal corpora deal with the situation ?

Skantze and Manfred Tscheligi: Furhat goes to Robotville: A large-scale human-robot interaction data collection in a public space Anders Grove: Automatic analysis of hand movement phases in video speech Yasuharu Den and Tomoko Kowaki: Annotation and preliminary analysis of eating activity in multi-party table talk Patrizia Paggio and Costanza Navarretta: Classifying the feedback function of head movements and face expressions Jens Allwood and Elisabeth Ahlsén: Incremental collection of activity-based multimodal corpora and their use in activity-based studies A framework for the acquisition of multimodal human-robot interaction data sets with a whole-system perspective A framework for the acquisition of multimodal human-robot interaction data sets with a whole-system perspective . Introduction Currently, the creation of a multimodal corpus involves the recording, annotation and analysis of a selection of many possible communication modalities such as speech, hand gesture, facial expression, and body posture. Simultaneously, an increasing number of research areas are transgressing from focused single modality research to full-fledged multimodality research. Multimodal corpora are becoming a core research asset and they provide an opportunity for interdisciplinary exchange of ideas, concepts and data. The 8 th Workshop on Multimodal Corpora is again collocated with LREC, which has selected Speech and Multimodal Resources as its special topic. This points to the significance of the workshop's general scope, and the fact that the main conference special topic largely covers the broad scope of our workshop provides us with a unique opportunity to step outside the boundaries and look further into the future, and emphasize the fact that a growing segment of research takes a view of spoken language as situated action, where linguistic and non-linguistic actions are intertwined with the dynamic conditions given by the situation and the place in which the actions occur. As a result, the 2012 Workshop on Multimodal Corpora holds a number contributions which share a focus on the acquisition, description, and analysis of situated multimodal corpora. Abstract Recent advances in emotion and affect recognition can play a crucial role in game technology. Moving from the typical game controls to controls generated from free gestures is already in the market. Higher level controls, however, can also be motivated by player's affective and cognitive behavior itself, during gameplay. In this paper, we explore player's behavior, as captured by computer vision techniques, and player's details regarding his own experience and profile. The objective of the current research is game adaptation aiming at maximizing player …
Vaginal flap for urethral neomeatus reconstruction after radical surgery for vulvar cancer: a retrospective cohort analysis

Introduction Partial urethrectomy during radical surgery for vulvar cancer may help avoid adjuvant radiotherapy in some patients. This study aimed to evaluate surgical, oncologic, and urinary outcomes of a new surgical technique based on vaginal flap to perform neomeatus reconstruction after distal urethral resection in radical surgery for vulvar cancer. Methods Retrospective cohort study between January 2005 and December 2017. We recorded data on pre- and post-operative urinary symptoms, surgical procedures, complications, adjuvant therapy, and follow-up of all patients who underwent surgery for vulvar cancer and had distal urethral resection and neomeatus reconstruction with the proposed technique. The reconstruction was based on the development of a vaginal flap in which a circular opening was created to become the neo-outlet of the urethra. Results Of a total of 200 patients with vulvar cancer operated with curative intent, 33 (16.5%) underwent distal urethral resection and neomeatus reconstruction during surgery (median age 73 (range 57–89) years; median body mass index 25.3 (range 16.3–36.4) kg/m2). Urethrectomy allowed the avoidance of adjuvant radiotherapy in 15/33 (45.5%) patients. No case of dehiscence was reported at the site of neomeatus. After a median follow-up of 39 (range 14–151) months, only one case of deviated urinary stream (3%) and no cases of neomeatus stricture were reported. Six (18.2%) patients developed or worsened urinary incontinence after urethral resection and neomeatus reconstruction, and there was no difference in the prevalence of urethral compressor muscle involvement during urethrectomy (p=0.19) and adjuvant radiotherapy (p=1.00). No recurrences were reported at urethral margins. Conclusions Distal urethral resection and neomeatus reconstruction seem to be associated with adequate healing and low complication rates, such as dehiscence, stenosis, and flux deviation/dribbling. New-onset or worsened urinary incontinence does not seem to be associated with urethral compressor muscle involvement during urethral resection or adjuvant radiotherapy.
Family history of prostate cancer and the incidence of ERG‐ and phosphatase and tensin homolog‐defined prostate cancer

Family history is among the strongest known risk factors for prostate cancer (PCa). Emerging data suggest molecular subtypes of PCa, including two somatic genetic aberrations: fusions of androgen‐regulated promoters with ERG and, separately, phosphatase and tensin homolog (PTEN) loss. We examined associations between family history and incidence of these subtypes in 44,126 men from the prospective Health Professionals Follow‐up Study. ERG and PTEN status were assessed by immunohistochemistry. Multivariable competing risks models were used to estimate hazard ratios (HR) and 95% confidence intervals (CI) for associations between self‐reported family history of PCa and molecular subtypes of disease. Thirteen percent of men had a positive family history of PCa at baseline. During a median follow‐up of 18.5 years, 5,511 PCa cases were diagnosed. Among them, 888 were assayed for ERG status (47% ERG‐positive) and 715 were assayed for PTEN loss (14% PTEN null). Family history was more strongly associated with risk of ERG‐negative (HR: 2.15; 95% CI: 1.71–2.70) than ERG‐positive (HR: 1.49; 95% CI: 1.13–1.95) disease (pheterogeneity: 0.04). The strongest difference was among men with an affected father (HRERG‐negative: 2.09; 95% CI: 1.64–2.66; HRERG‐positive: 1.30; 95% CI: 0.96–1.76; pheterogeneity: 0.01). Family history of PCa was positively associated with both PTEN null (HR: 2.10; 95% CI: 1.26–3.49) and PTEN intact (HR: 1.72; 95% CI: 1.39–2.13) PCa (pheterogeneity: 0.47). Our results indicate that PCa family history may be positively associated with PCa in all ERG and PTEN subtypes, suggesting a role of genetic susceptibility in their development. It is possible that ERG‐negative disease could be especially associated with positive family history.
The relationship between peripheral hearing loss and higher order listening function on cognition in older Australians

Abstract Objective: Peripheral hearing, central auditory processing (CAP) and cognition are all important for comprehension of speech and deteriorate with increased age. This study aimed to examine the relation between hearing impairment and cognitive impairment by assessing both peripheral hearing impairment and CAP ability. Design: Cognition was measured using the CogState Brief Battery (CSBB). Peripheral hearing was measured across eight frequencies (250 Hz–8000 Hz) using pure tone audiometry, and CAP was measured using the Listening in Spatialised Noise-Sentences test (LiSN-S) and the Dichotic Digits Test. Data were analysed using correlation and regression analyses. Study sample: Around 85 adults aged 60.33–83.08 years who attended the Melbourne Audiology clinic and had no previous diagnosis of dementia were included in the study. Results: A significant association was found between degree of peripheral hearing impairment and the cognitive skills of attention and executive function as measured by the CSBB. Additionally, CAP abilities as assessed using the LiSN-S test were significantly correlated with at least one cognitive measure. Conclusions: This study adds to the knowledge that peripheral hearing and CAP ability both share an association with cognition, specifically identifying cognitive skills and measures of “hearing” that mediate this relationship.
A Conceptual Approach to Designing Transposition Flaps.

BACKGROUND The large number of transposition flap geometries available for cutaneous reconstruction often makes the design of these flaps difficult for less experienced dermatologic surgeons. OBJECTIVE To present a conceptual approach to designing transposition flaps based on 2 elementary angles. MATERIALS AND METHODS First, a simplified framework for designing transposition flaps is presented, based on: (1) the takeoff point of the flap, (2) the angle between the primary limb and the primary defect (Angle A), and (3) the angle between the secondary limb and the primary limb (Angle B). Next, a comprehensive literature review highlights applications of the above conceptual approach in the design of z-plasties and single-lobed and multi-lobed transposition flaps. RESULTS Different types of transposition flaps all share the same key design elements, and modifications to Angle A and Angle B predict flap biomechanics. CONCLUSION The design of transposition flaps can be simplified by understanding how 2 elementary angles influence the geometry and biomechanics of various transposition flaps.
A New Method for Model-Based Health Economic Evaluation Utilizing and Extending Moment-Generating Functions

Background. Health economic evaluations frequently include projections for lifetime costs and health effects using modeling frameworks such as Markov modeling or discrete event simulation (DES). Markov models typically cannot represent events whose risk is determined by the length of time spent in state (sojourn time) without the use of tunnel states. DES is very flexible but introduces Monte Carlo variation, which can significantly limit the complexity of model analyses. Methods. We present a new methodological framework for health economic modeling that is based on, and extends, the concept of moment-generating functions (MGFs) for time-to-event random variables. When future costs and health effects are discounted, MGFs can be used to very efficiently calculate the total discounted life-years spent in a series of health states. Competing risks are incorporated into the method. This method can also be used to calculate discounted costs and health effects when these payoffs are constant per unit time, one-off, or exponential with regard to time. MGFs are extended to additionally support costs and health effects which are polynomial with regard to time (as in a commonly used model of population norms for EQ-5D utility). Worked Example. A worked example is used to demonstrate the application of the new method in practice and to compare it with Markov modeling and DES. Results are compared in terms of convergence and accuracy, and computation times are compared. R code and an Excel workbook are provided. Conclusions. The MGF method can be applied to health economic evaluations in the place of Markov modeling or DES and has certain advantages over both.
Partheno Genetic Algorithm for Solving Job-shop Scheduling Problem

A Integer Coded Partheno Genetic Algorithm(IPGA) is designed for Job-Shop Scheduling Problem(JSSP). This algorithm strengthens the unitary capability of scheduling algorithm,not only has the virtue of PGA,such as small calculation capacity,no immature convergence and so on,but also incarnates technics constraint condition in coding,such as keeping job shop scheduling sequence.Considering different sizes of FT emulation results problems show that the convergence expedites as size extends,and can give good stable solutions for solving job shop problems.