Miracle-dz/UniFAR-FTUs huggingface dataset:
Hydrogen storage in a layered flexible [Ni2(btc)(en)2]n coordination polymer

[Ni2(btc)(en)2]n coordination polymer exhibits a layered two-dimensional structure with weak interaction between the layers. Correlation of experimental measurements and DFT calculations and molecular simulations demonstrated that its structural features, primarily the inherent flexibility of the layered polymeric structure, lead to improved hydrogen storage performance at room temperature, due to significant enhancement in isosteric heats of hydrogen adsorption. Volumetric measurements of hydrogen adsorption at room temperature show up to 0.3 wt. % hydrogen absorbed at 303K and 2.63 bar of hydrogen pressure, with isosteric heats of adsorption of about 12.5 kJ mol. Predicted performance at room temperature is 1.8 wt. % at 48 bar and 3.5 wt. % at 100 bar, better than both MOF-5 and NU-100, with calculated values of isosteric heats for adsorption of hydrogen are in 8-13 kJ mol range at both 77K and 303K. Grand canonical Monte Carlo calculations show that this material, at 77K, exhibits gravimetric hydrogen densities of more than 10 wt. % (up to 8.3 wt.% excess) with the corresponding volumetric density of at least 66 gL, which is comparable to MOF-5, but achieved with considerably smaller surface area of about 2500 mg. This study shows that layered two-dimensional MOFs could be a step towards MOF systems with significantly higher isosteric heats of adsorption, which could provide better room temperature hydrogen storage capabilities. email: vladab64@gmail.com email: dminic@ffh.bg. ac.rs
Early laparoscopic cholecystectomy improves outcomes after endoscopic sphincterotomy for choledochocystolithiasis.

BACKGROUND & AIMS Patients with choledochocystolithiasis generally undergo endoscopic sphincterotomy (ES) followed by laparoscopic cholecystectomy (LC). However, many patients receive this surgery 6-8 weeks after ES. There is a high conversion rate of elective LC after ES, and patients can develop recurrent biliary events during the waiting period. We investigated whether the timing of surgery influences outcome. METHODS We performed a randomized trial of patients with choledochocystolithiasis who underwent successful ES. Patients were randomly assigned to groups that received early LC (within 72 hours after ES, n = 49) or delayed LC (after 6-8 weeks, n = 47), based on an expected difference in conversion rate of 25% vs 5%, respectively. Conversion rate, biliary events during follow-up, duration and difficulty of surgeries, postoperative morbidity, and hospital stay were scored. Intention-to-treat analyses were performed. RESULTS Groups were comparable in age, sex, and comorbidity. There was no difference between groups in conversion rate (4.3% in early vs 8.7% in delayed group) nor were there differences in operating times and/or difficulties or hospital stays. During the waiting period for LC, 17 patients in the delayed group (36.2%) developed recurrent biliary events compared with 1 patient in the early group (P < .001). CONCLUSIONS In a randomized trial to evaluate timing of LC after ES, recurrent biliary events occurred in 36.2% of patients whose LC was delayed for 6-8 weeks. Early LC (within 72 hours) appears to be safe and might prevent the majority of biliary events in this period following sphincterotomy.
Study of insulin resistance among Chinese population over 40 in Shanghai area

Objective To evaluate the reliability of homeostasis model assessment (HOMA) for estimating insulin sensitivity, as well as to investigate the insulin resistance of base line survey people by HOMA IR. Methods The hyperinsulinemic euglycemic clamp combined with 3 3H glucose infusion were performed in 29 Chinese individuals to determine the glucose disposal rate and assess the sensitivity, specificity and accuracy of HOMA IR (HOMA insulin resistance index). The current status of insulin sensitivity in Shanghai Huayang community survey(n=1873)was estimated by HOMA IR. Results 1.In comparison with the glucose disposal rate by glucose clamp, the sensitivity、specificity、accuracy of HOMA IR was 86.4%、71.4% and 82.8%, respectively. 2. In diabetes、impaired glucose tolerance and/or impaired fasting glucose、hypertriglyceridemia and/or low high density lipoprotein cholesterol(H TG/L HDL) and hypertensives, about 62.5%、41.7%、30.8% and 32.0% suffered from insulin resistance respectively. 3.With the rise of BMI or metabolic disorders, the frequency of insulin insensitivity was also increased (P for trend, P 0.001). 4. Results of logistic regression analysis revealed that insulin resistance had a major effect on hyperglycemia, and that on H TG/L HDL being the next. Conclusion HOMA IR in the estimation of insulin resistance has a higher accuracy,while insulin resistance is common among the adults, especially in those with metabolic disorders.
Turning around reading achievement: Predictors of high school students' academic resilience

In a national, longitudinal database, factors were examined that enabled public school students on a path toward failure to significantly improve reading achievement by high school graduation. Youths who faced the proximal risk of low achievement during the transition to high school were vulnerable to continued low achievement or failure; yet, a small number improved reading proficiency from failing the basic level to passing the intermediate or advanced levels. Being Caucasian, being female, having an internal locus of control, and taking an academic curriculum in high school independently predicted academic resilience. The role of student socioeconomic status in predicting resilience was explained by psychological and school environment variables. The path between locus of control and resilience was partly mediated by high school curriculum; the path between 8th-grade educational aspirations and resilience was fully mediated by curriculum.
La Biblioteca Max von Buch de la Universidad de San Andrés y sus investigadores: Segunda parte de Un estudio de las necesidades de información, hábitos y características de Investigadores en Humanidades y Ciencias Sociales

As mentioned in the previous article, the present study was conducted to understand and identify the characteristics, needs and habits of research from the Humanities and Social Sciences researchers at the Universidad de San Andres (UdeSA). This second part tries to identify and evaluate their performance at the Max von Buch library of the University through the services that it provides them. The results of the survey are presented, together with the second part of the questionnaire, with the aim of identifying information needs.
REFRAME: Resilience training for GPs

We need more GPs in the UK if we are to manage our ageing and increasingly multi-morbid population. However, there is a manpower crisis in NHS primary care, with GP recruitment falling and older doctors taking early retirement. Although there has been considerable research into medical staff stress, there are relatively few studies of coping and resilience in doctors. However, there is some evidence that intensive, brief resilience training can be beneficial. Our aim was to establish if REFRAME could help GPs develop skills that improve their well-being and resilience and to establish whether participants feel the outcome measures employed capture their experience.
Randomized radiostereometric study comparing Osteogenic Protein-1 (BMP-7) and autograft bone in human noninstrumented posterolateral lumbar fusions

Study Design. Randomized efficacy trial comparing two types of noninstrumented posterolateral fusion between L5 and S1 in patients with L5 spondylolysis and vertebral slip less than 50%, as evaluated by radiostereometric analysis. Objective. To determine whether osteogenic protein-1 (BMP-7) in the OP-1 Implant yields better stabilizing bony fusion than autograft bone. Summary of Background Data. Animal studies of osteoinductive proteins in noninstrumented posterolateral fusions have shown high fusion rates. No similar conclusive study on humans has been performed. Methods. For this study, 20 patients were randomized to fusion with either OP-1 Implant or autograft bone from the iliac crest, 10 in each group. The patients were instructed to keep the trunk straight for 5 months after surgery with the aid of a soft lumbar brace. At surgery 0.8-mm metallic markers were positioned in L5 and the sacrum, enabling radiostereometric follow-up analysis during 1 year. The three-dimensional vertebral movements, as measured by radiostereometric analysis induced by positional change from supine posture to standing and sitting, were calculated with an accuracy of 0.5 to 0.7 mm and 0.5° to 2.0°. Conventional radiography was added. Results. No significant difference was noted between the radiostereometric and radiographic results of fusion with the OP-1 Implant and fusion with autograft bone. There was a significant relation between reduced vertebral movements and better bone formation. No adverse effects of the OP-1 Implant occurred. Persistent minor pain at the iliac crest was noticed in one patient. Conclusions. There was no significant difference between the two fusion versions. Thus, the OP-1 Implant did not yield better stabilizing bony fusion than autograft bone. [
The expression of cyclooxygenase-2(COX-2) in human colorectal cancer and its clinical significance

Purpose:To evaluate the role of COX 2 in the carcinogenesis and progression of human colorectal neoplasms. Methods:The expression level of COX 2 in 122 colorectal neoplasm tissues(including 35 colorectal adenomas, 67 colorectal carcinoma and 23 colorectal cancer with synchoronous hepatic metastasis) was assayed by immunohistochemical methods. All specimens was analyzed by Conformation quantitative assay system, their stain strength was calculated.Results:Conformation quantitative assay showed the mean stain strength is 704.5 131.8 in colorectal adenoma, 1197.2 204.3 in colorectal cancer without hepatic metastasis and 1901.2 324.8 in colorectal cancer with synchoronous hepatic metastasis, there are significant differences among them statistically. According to the Dukes stages, mean stain strength is 1145.3 187.0 in B stage,1237.0±298.7 in C stage,1901.2 in D stage. There is statistic difference between Dukes stage D and B, C. Also our study indicated there was no relationship between age, sex, tumor location, tumor differentiation or tumor size with the level of COX 2 protein expression.Conclusions:In our test,higher COX 2 expression is seen in colorectal cancer than colorectal adenomas, colorectal cancer with synchoronous hepatic metastasis than colorectal cancer without hepatic metastasis,and Dukes D stage than the B? C. Thus COX 2 responses is important in the carcinogenesis and progression of colorectal cancer. NSAIDs or the others may play a role in the chemoprevention strategies of colorectal neoplasm as the COX 2 inhibitor.
STABILIZATION AND BALANCE EXERCISE BENEFITS IN AMYOTROPHIC LATERAL SCLEROSIS: A CASE REPORT

Background: ALS is the most devastating form of motor neuron disease, and the chance of survival is 3 to 5 years after the diagnosis is made. The pathogenesis of the disease is unknown. Several upper and lower motor neuron symptoms such as weakness, gait bradykinesia, and muscle atrophy have been reported. The core muscles are considered to be the center of the functional kinetic chain due to the links with upper and lower limbs. Methods: The patient in this case study was a 42 year-old woman suffering from ALSfor two years prior to the study. She had typical upper and lower motor symptoms, but her chief complaints were inability to walk, standing balance impairment, and a tendency to fall posteriorly. She performed core stabilization exercises, which were done three times per day. She was followed for three months. Results: Core stabilization exercises improved her quality of life, and she could walk independently after three months of exercise. In addition, her tendency toward falling posteriorly was completely alleviated. Conclusion: Core stabilization exercises were beneficial to the patient, and she was satisfied because her quality of life had improved.
Parent Management Training in Primary Care: Feasibility, Acceptability, and Preliminary Results

This study explores the notion that brief interventions delivered in primary care can lead to positive outcomes in children with externalizing behavior problems. Study aims explored behavioral problem prevalence, whether caregivers found it acceptable to receive brief behavioral interventions following routine pediatric visits for identified behavioral problems, and whether it was feasible to deliver same-day services in a primary care setting. Additionally, preliminary data were provided regarding a small N randomized control trial conducted in a primary care setting. The trial utilized either a one-session intervention comprised of evidencebased Parent Management Training components or a supportive therapy intervention for children with externalizing behavioral problems. Participants were 100 caregivers and their children (Mage = 5.32 years, 54% female, 54% White) with disruptive behavior problems. Results revealed that more than half of caregivers (53%) endorsed one or more observed behavioral problems with their child. When offered help for identified problems, caregivers largely refused help and when they did accept help they were largely unable to stay for a same-day behavioral health visit. Preliminary small N trial data were provided by caregivers of 6 children (Mage = 5.50 years, 83% male, 67% White). Results indicated positive behavioral improvements in both children and caregivers, although caregiver knowledge regarding specific PMT components did not improve. TABLE OF CONTENTS
Splice Site Mutation-Induced Alteration of Selective Regional Activity Correlates with the Role of a Gene in Cardiomyopathy

Splice site mutations of a number of genes are found to induce cardiomyopathy. The mutation alters the thermodynamic activity of nucleotide fragment around the splice sites, which causes exon skipping, leading to dysfunction of certain genes. In the present study, we analyzed the selective and regional characteristic of splice site mutations for genes contributed to the development of cardiomyopathy. 93 splice site mutations in total 16genes involved in cardiomyopathy were analyzed for the information content (Ri). Exon skipping (Ri value<0) appeared to correlate with hypertrophic cardiomyopathy and arrhythmogenic right ventricular dysplasia, the two cardiomyopathies with the highest mortality. We also found that most of the exon skipping was due to the donor splice site mutations instead of the acceptor site mutations at the splice junction. Our studies revealed that the regional preference of mutations at the donor sites is an important factor in determining whether or not the gene plays a role in the development of cardiomyopathies
Correlation between the quality indicators of activated coal in vodka technology

Introduction. The purpose of the publication is to establish correlation relations between the quality indicators of active coal (AC) used in the distillery production in vodka technology. Materials and methods. AC of natural origin, which is used for distillery production. Standard methods of determination and quantitative characteristics of AC quality indicators. Mathematical-statistical methods of research are linear correlation analysis based on the Pearson correlation coefficient. Results and discussion. It was found that the correlation coefficient ( r ) between iodine adsorption activity ( A i. ), which characterizes the amount and volume of micropore AC with diameter D m <2 nm, including nanopor with diameter D m <1 nm, and methylene blue ( A m.b. ), which depends on the mesopore volume with a diameter D me =2…50 nm, is equal to 0.93. The total volume of the micro- and mesoporous space determines the total sorption capacity of AC relative to the organic impurities present in the water-alcohol mixtures. AC's sorption activity also depends on its fractional composition. The correlation (reverse dependence) between adsorption activity on acetic acid ( A a.a. ) and the mass fraction of the sorbent residue on a screen with a cloth №10 ( F №10 ) with a coefficient r =-0,94 was established. Reducing the mass fraction of the residual on a screen with a cloth from 97…98% to 62…64% leads to an increase in adsorption activity of AС by acetic acid to 117 ml versus 62 ml. This is directly due to the fact that the residual sorbent on the sieve content of
Origin and Evolution of Earth and Life: Towards the Establishment of Astrobiology from Universe to Genome

This paper is comprised of 6 sections as follows. (1) Introduction (2) Planetary Formation Theory and Origin of Earth (3) Origin of a habitable planet: carbon cycle (4) Origin of the Earth’s life (5) Evolution of the Earth’s life (6) Towards the establishment of Astrobiology In (1) Introduction, I briefly summarized why I came to involve in these research topics. In (2) Planetary Formation Theory and Origin of Earth, we simply review previous researches of planetary formation theory, and introduce newly proposed Tandem model to explain the formation of the solar system with new factor. Then, we introduce the ABEL model as another new theory to explain how the Earth was formed. This model can explain long unsolved enigma of the origin of earth’s water and solid earth. In (3) Origin of a habitable planet: carbon cycle, we try to explain the significance to unravel the carbon cycle through earth’s history. And we propose new concept of carbon cycle from atmosphere to mantle through earth’s history from the birth of earth to present day. In addition, based on accretionary complex geology centering on Ocean Plate Stratigraphy (OPS), we propose carbon compensation depth (CCD) works as the function of pCO2 through time, which is significantly new method to approach environmental evolution of the earth. In (4) Origin of the Earth’s life, after we review previous researches for the birthplace of life, we propose nine requirements that must be met at the birthplace of life. Then, we introduce an ideal site to emerge life is Natural geyser system on the Hadean primordial continent, which produce material circulation system to synthesize life by the combination between natural nuclear reactor and geyser. In (5) Evolution of the Earth’ life, we pick up 20 biggest events in the history for the earth and life, to understand more essential and significant events to study the history of earth and life. Those events were selected considering the criterion to extract, whether the event is single and unique phenomenon to become a turning point for the earth’s history. In (6) Towards the establishment of Astrobiology, we propose the working hypothesis to push forward the present Astrobiology research. Astrobiology is the research field to unravel when, how, and where in the universe life was born. To tackle with such a big question, fundamental requirements must be clarified. The conditions to evolve to a habitable planet, which we propose here, is comprised of three groups; (1) planetary requirements to be life emerging planet, (2) nine requirements for the birthplace, and (3) requirements to evolve into planet with civilization. Totally 40 requirements are picked up, and each condition must be satisfied in sequence as listed. It means the emergence of life is not easy. The order and number of requirements that must be satisfied make life very difficult even to appear, suggesting the planet with civilization might be quite rare in our Galaxy.
Opening Eyes into Inclusion and Diversity

In Australia and internationally much still needs to occur to promote inclusive practices in education and society with many educators not feeling equipped to recognise or appreciate diversity or cater effectively for inclusion (Hardy & Woodcock, 2015). It is into this space that a University of Southern Queensland team of researchers, practitioners, and academics intends to contribute an open textbook 'Opening Eyes onto Inclusion and Diversity'. With embedded audio–visual components, the Open Textbook is designed to enhance the quality of the reader’s experience with each chapter posing key understandings underpinning inclusion and diversity. Readers are encouraged to answer questions on culture, special learning needs, varied educational contexts, gender diversity and more. The key expected outcome of this open textbook is to engage readers in making meaning of inclusion and diversity and applying their learning to their own individual contexts.
Motivos del Voluntariado: Categorización de las Motivaciones de los Voluntarios Mediante Pregunta Abierta

La mayoria de los estudios sobre motivaciones del voluntariado utilizan cuestionarios estandarizados, siendo el Volunteer Funcion Inventory (VFI) el mas utilizado. En muy pocas ocasiones se pregunta de forma abierta a los voluntarios por los motivos que les llevan a serlo. En este trabajo hipotetizamos que los cuestionarios tiende a sobreestimar el numero de motivaciones y a infraestimar la variedad de las mismas, por lo que se analizan las respuestas cualitativas de 1515 voluntarios a una pregunta abierta por sus motivaciones y se realiza una categorizacion de las mismas. Los resultados muestran que los voluntarios dan una media de dos motivos, muy por debajo de lo aportado por los cuestionarios, y que Valores es la motivacion mas frecuentemente citada y la considerada mas importante por la mayoria. Ademas, esta motivacion parece coexistir con otras motivaciones muy diversas, no contempladas en los cuestionarios, como Compromiso Organizacional, Religiosidad, Cambio Social, Interes por la Actividad o Desarrollo Personal.
The influence of hydro-climatological balances and Nature-based solutions (NBS) 
in the management of water resources

This article offers a historical review of (cognitive) scientific research that demonstrates the development of key concepts relating to balances in the hydrological and hydro-climatic cycles, thereby supplying a basis for quantitative and qualitative assessment of renewable water resources. The review reveals the direction knowledge took as it developed through successive cognitive and applied stages. The emphases are on how global and regional hydrological conditioning underpin integrated concepts for the management of water resources. The primary aim of this article is to describe the main achievements, approaches and scientific initiatives, along with their theoretical underpinnings, in the hope of encouraging application and further appreciation. Attention is thus paid to milestones along the road to global development, as manifested in the (at times abruptly changing) effort to better assess and understand the use of water resources in various economic, social and ecological activities. The aim is first and foremost to encourage the achievement of sustainable development as humankind’s main hope for the future. A further focus is on initiatives, scientific issues, and concepts that have been espoused by international organisations and illustrate the increasingly essential harmonious use of water resources at local, regional, continental, and planetary scales. Relevant global conferences have demonstrated wide readiness to adopt declarations, or to issue appeals and resolutions, in support of fuller assessment of renewable water resources. Examples of excessive use have been identified, and efforts have been made to counteract both floods and deficits, and hence avoid crises. These deliberations have also stimulated long-term forecasting, for periods up to 2030 or even 2050. Also stressed here are the challenges, inspirations, and achievements of pure and applied science when it comes assessing the risk that the Earth’s potential to supply water resources will be exceeded. The suitability of current assessments of water resources is evaluated, and reference made to ecologically-integrated answers such as Nature-based solutions (NBS), as backed by the UN and UNESCO (2018) in combination with principles set out in the EU’s Water Framework Directive (2000/60/EC).