Miracle-dz/UniFAR-FTUs huggingface dataset:
Upper aerodigestive tract carcinoma: Development of a (epi)genomic predictive model for recurrence and metastasis

Despite the increased molecular knowledge and the diagnostic and therapeutic improvements, the survival of patients with upper aerodigestive tract carcinoma remains poor. The identification of early diagnostic and prognostic biomarkers and the development of molecular models to distinguish patients that will recur and/or develop metastasis after treatment as well as to benefit with target therapies can be important to decrease mortality, improve survival rates and improve the quality of life of these patients. The current study analyzed 21 upper aerodigestive tract carcinomas through array comparative genomic hybridization and methylation-specific multiplex ligation-dependent probe amplification techniques. A number of chromosomal regions and genes were observed with copy number alterations and methylation. A predictive (epi)genomic model that comprises the 3p chromosomal region and WT1, VHL and THBS1 genes was built, highlighting a molecular signature with possible clinical use. The current study may aid in the development of a more individualized patient management and targeted drug design. The power of this genomic and epigenetic model to predict the recurrence and metastasis development should be evaluated and validated in future larger cohort study.
Pattern Detection for Large Data Sets in a Distributed Computing Environment

Large amounts of data generated from social media is stored as it is generated. There exists many different ways to store and retrieve data, however constant efforts are being made in order to make these methods more efficient. This paper explores some of the more popular methods used to retrieve useful and specific information from large data sources. This paper also explores different ways of processing this information via pattern recognition algorithms to gain insight that may otherwise not be immediately obvious. This paper does not explore data mining in the social media context exclusively, but rather the underlying concepts behind data mining itself
Validation of a Four-Factor Measurement Model of the Health Promoting Lifestyle Profile-II: a Confirmatory Study with Kenyan Undergraduate Students

Due to the rise of unhealthy lifestyles among the young population, there is a need to develop a tool to assess their healthpromoting behavior. Despite the importance of this issue, few studies have explored the Health-Promoting Lifestyle Profile (HPLP) among students, and literature from the East African region for this particular group is even more scarce. Objective. The main aim of this study was to validate a four-factor structure measurement model of the Health-promoting lifestyle Profile-II (HPLP-II) based on CFI, SRMR, and RMSEA among Kenyan undergraduate students Design. The study design was a cross-sectional analytical, that utilized quantitative methods Setting. The study was conducted in Kakamega County, located in Western Kenya. Analysis. Data were analyzed through confirmatory factor analysis, which was conducted using robust maximum likelihood estimation. The factor model was tested for validity and construct validity. Main outcome measures. Subscales physical activity, nutrition, interpersonal relationship and stress management of the Health-Promoting Lifestyle Profile II Results. After omission of some items due to high correlation with variables in the same factor, a final 34 item model was analyzed. The overall 34-item tool had a Cronbach’s alpha of 0.79 indicating good reliability. The factors physical activity, stress management, nutrition, and interpersonal relationship had Cronbach coefficients of 0.70, 0.80,0.81 and 0.83 respectively. All the correlations were below the recommended cut-off point of 0.85, which indicated that the four-health promoting behavior factors achieved good discriminant validity. The RMSEA index was less than . 08, RMSEA = 0.07, 90% CI = [0.07, 0.08], which is indicative of a good model fit. The SRMR was between . 05 and . 08, SRMR = 0.08, which implies that the model fits the data adequately, however the CFI (CFI=0.81 which is less than 0.9) and chi-square goodness of fit test (was significant χ 2 (318) = 686.69, p < . 001,) indicated poor model fit. Conclusion. In conclusion, within the limitations of this study, the results showed that confirmatory factor analysis yielded a partially good final measurement model. This study recommended that further research should examine the replicability of the HPLP-II in more diverse Kenyan speaking populations.
Measuring Spatial Cross Sections of Ultrasound Pressure Fields by Fast Optical Means

Recently, major improvements in transducer technology for producing and detecting ultrasound were made. To achieve acousto-electrical receivers with reasonable twodimensional array sizes and small pixels, a huge number of electronic elements is necessary. Optical methods offer alternative concepts with small spot sizes for high spatial resolution as well as high bandwidth and parallel data processing facilities like CCD chips. An optical multilayer hydrophone is presented that allows the twodimensional determination of ultrasound pressure fields by measuring the sound-induced change of reflectivity of a thin-film Fabry-Perot interferometer coating on a glass substrate. The extension of recently established point measurements to the automated two-dimensional acquisition of ultrasound pressure fields is shown. For serial two-dimensional acquisition, a laser beam is scanned across the sensor probe by a micro-mechanically engineered scanning mirror and the pressure waveforms are acquired point by point. In an alternative approach incorporating a commercial CCD camera, the probe is strobe illuminated by a large-diameter collimated beam of a pulsed laser diode and the two-dimensional pressure distribution at a particular moment is derived from the captured reflectivity distribution. Measurement results on ultrasound fields from plain and focussing transducers obtained by these two different approaches are presented and individual advantages and drawbacks and discussed.
Teacher Conceptions of Care and the Impact on Elementary School Students

BARTLEY, APRIL YOUNG. Teacher Conceptions of Care and the Impact on Elementary School Students. (Under the direction of Dr. Patricia Marshall.) The emphasis of this study is to understand the conceptions and manifestations of care within the context of the elementary classroom as determined by caring teachers, and how these caring teachers respond to differences among student ethnicities within their conceptions and manifestations of care. This study also looked at the perceived impact of care on students. The definition of care used in this study that arose out of the research literature is the trusting, respectful and supportive relationship between the teacher (care giver), and the students (care receivers), within the classroom setting. By looking at how ethnicity of the student population impacts teacher perceptions of care, this study furthered the extant research on the topic of teacher care. Data was collected for this research through semi-structured interviews with ten caring elementary teachers. These teachers were each allowed to explain and construct their definitions of care, how they manifest care within the classroom, and the impact of care on students. From these constructions, common themes emerged defining care, explaining how it is shown in the classroom, and how it impacts students. Overall this research accomplished the goals of understanding teacher constructions of care and its manifestation in the classroom and impact on students. However, the results were inconclusive on the impact of student ethnicity on the teacher constructions. What emerged regarding care in ethnically diverse classrooms is that caring teachers look at each student as an individual, and seek to teach each student with the care most appropriate to them. In addition, caring teachers love and respect their students and are respected in return. Further research on the topic of teacher care within the context of ethnically diverse classrooms may include interviewing students to provide their perspective on the impact of teacher care. Additionally research on the impact of care on student motivation may also be beneficial. Teacher Conceptions of Care and the Impact on Elementary School Students by April Young Bartley A thesis submitted to the Graduate Faculty of North Carolina State University in partial fulfillment of the requirements for the Degree of Master of Science Curriculum and Instruction, Elementary Education Raleigh, NC 2007
Income Distribution and Political Economy of Allocation of Public Education Spending ∗

Over the last 30 years, countries with more unequal income distributions tended to spend more on tertiary education and less on secondary education. During the same period of time, countries spending more on tertiary (secondary) education in one decade tended to experience more (less) unequal income distribution in the next decade. Thus, the relationships between the allocation of education spending and income distribution provide a potential explanation for persistent inequality. This paper develops a political economy model capable of accounting for these stylized facts. The allocation of public education expenditure is the outcome of the interaction between an incumbent government and lobbies representing different socio-economic classes. Unlike previous studies of political influences, the formation of lobbies is endogenous in my model, and is determined by the parameters of the economy. The model generates an abundant assortment of lobby formation equilibria and income distribution dynamics. In particular, it shows that in a more unequal economy, the rich tend to capture the political power, which in turn leads to more unequal income distribution for the future generations, and vice versa. ∗I would like to thank Douglas Bernheim, Daniel Eisenberg, Eric Hanushek, Robert Inman, Chad Jones, Shujing Li, Zhi Liu, Sita Nataraj, Antonio Rangel, and the Public Economics Group at Stanford University. Financial support from the Olin Program in Law and Economics is gratefully acknowledged.
Research Effectiveness of Corporate Culture to Employee’s Loyalty at Lilama 7 Joint Stock Company

This paper goes towards 2nd purpose to study the impact of these factors corporate culture (CC) to employee’s loyalty (EL). Since then built models depth study of the relationship CC to the MW research and application in practice in Lilama7. The study results showed that the factors that CC has a strong impact on employee’s loyalty in Lilama7.
An Interactive Tool for Computer-Aided Refactorization of Java Source Code

Code refactorings are source code changes that do not change the behavior of a program, only its structure. They are applied to make the code easier to modify and understand. Many IDEs already have prebuilt refactorings. Some of them enable the user to program his own refactorings like the Eclipse LTK framework. However, this framework has a steep learning curve and does not allow for interactive development. To ease the task of creating refactorings there are scripting tools that either are standalone (Recoder, Inject/J) or use the facilities of an IDE but hide their complex interface (JTransformer, JunGL). The current tools use DSLs (Domain Specific Languages), the language of the target program (in this case Java) or other general purpose languages like Prolog. Usually the tools that use imperative languages lack a more expressive querying, when the other more declarative languages such as Prolog or DSL’s are less known languages with paradigms that are more expressive. We improve on that work by providing a transformation tool that combines both the expressiveness of logic for searching with imperative paradigm for transforming the AST. Instead of using a DSL we use JavaScript as scripting language. We evaluated our work by comparing other tools, by creating some academic transformations and by creating two transformations that were applied to the FenixEdu project’s source code.
Risk taking as a socially meaningful practice

Th e aim of this study is to understand the notion of risk in photo-sharing practices and the purpose of risk in the development of intimate relationships. We argue that risk in the form of self-disclosure is a key aspect of intimate photo sharing rather than an undesirable side eff ect, and that a broader analytical perspective on the role of risk in the development of intimate relationships allows us to understand risky photo sharing as a socially meaningful practice. We unfold and elaborate the link between risk and intimacy on the basis of fi ve focus group interviews with 21 German high school students aged 14 to 17. Th e interviews focus on the participants’ sharing practices and the associated role played by risk. Th e data indicate that risk does serve a social purpose as a way of ‘proving friendship’. However, the data also suggest that the young people in the study are more willing to accept risk related to ‘friendly intimacy’ as compared to ‘romantic intimacy’. We discuss the potential reasons for this diff erence as well as its wider methodological and theoretical implications.
Future Generation Computer Systems

Mobile edge computing is a new paradigm that can enhance the computation capability of end devices and alleviate communication traffic loads during transmission. Mobile edge computing is highly useful for emerging resource-hungry mobile applications. However, a key challenge for mobile edge computing systems is multiple resources allocation between Mobile Edge Clouds (MECs) and End Users (EUs), especially for multiple heterogeneous MECs and EUs. To address this problem, we propose a Stackelberg game-based framework in which EUs and MECs act as followers and leaders, respectively. The proposed framework aims to compute a Stackelberg equilibrium solution in which each MEC achieves the maximum revenue while each EU obtains utility-maximized resources under budget constraints. We decompose the multiple resources allocation and pricing problem into a set of subproblems in which each subproblem only considers a single resource type. The Stackelberg game framework is constructed for each subproblem wherein each player (i.e., an EU) can selfishly maximize its utility by selecting an appropriate strategy in the strategy space. We prove the existence of the subgame Stackelberg equilibrium and develop algorithms to determine the Stackelberg equilibrium for each resource type, including an optimal demand computation algorithm, to determine the best resource demand strategy for an EU and an iterative algorithm to find an equilibrium price. The equilibrium solutions of all subgames constitute the equilibrium solution of the original problem. We also conduct simulation experiments of our game, such as numerical data for the Stackelberg equilibrium, numerical data for the convergence of the Stackelberg equilibrium, and numerical data as the system size increases. Finally, we demonstrate that an EU with idle resources can play the role of an MEC.
Variations in Fe 3 þ / P Fe of Mariana Arc Basalts and Mantle Wedge f O 2

Arc basalts are more oxidized than mid-ocean ridge basalts, but it is unclear whether this difference is due to differentiation processes in the Earth’s crust or to a fundamental difference in the oxygen fugacity of their mantle sources. Distinguishing between these two hypoth-eses is important for understanding redox-sensitive processes related to arc magmatism, and thus more broadly how Earth materials cycle globally.We present major, volatile, and trace element concentrations in combination with Fe 3 þ / P Fe ratios determined in olivine-hosted glass inclusions and submarine glasses from five Mariana arc volcanoes and two regions of the Mariana Trough. For single eruptions, Fe 3 þ / P Fe ratios vary along liquid lines of descent that are either slightly oxidizing (olivine þ clinopyroxene þ plagioclase fractionation, CO 2 (cid:2) H 2 O degassing) or reducing (olivine þ clinopyroxene þ plagioclase (cid:2) magnetite fractionation, CO 2 þ H 2 O þ S degassing). Mariana samples are consistent with a global relationship between calc-alkaline affinity and both magmatic H 2 O and magmatic oxygen fugacity, where wetter, higher oxygen fugacity magmas display greater affinity for calc-alkaline differentiation. We find, however, that low-pressure differentiation cannot explain the majority of variations observed in Fe 3 þ / P Fe ratios for Mariana arc basalts, requiring primary differences in magmatic oxygen fugacity. Calculated oxygen fugacities of primary mantle melts at the pressures and temperatures of melt segregation are significantly oxidized relative to mid-ocean ridge basalts ( (cid:3) QFM, where QFM is quartz^fayalite^magnetite buffer), ranging from QFM þ 1 (cid:4) 0 to QFM þ 1 (cid:4) 6 for Mariana arc basalts, whereas backarc related samples record primary oxygen fugacities that range from QFM þ 0 (cid:4) 1to QFM þ 0 (cid:4) 5.This Mariana arc sample suite includes a diversity of subduction influences, from lesser influence of a homogeneous H 2 O-rich component in the back-arc, to sediment melt- and fluid-dominated influences along the arc. Primary melt oxygen fugacity does not correlate significantly with sediment melt contributions (e.g.Th/La), nor can it be attributed to previous melt extraction in the back-arc. Primary melt oxygen fugacity correlates strongly with indices of slab fluids (e.g. Ba/La) from the Mariana Trough through the Mariana arc, increasing by 1 (cid:4) 5 orders of magnitude as Ba/La increases by a factor of 10 relative to mid-ocean ridge basalts.These results suggest that contributions from the slab to the mantle wedge may be responsible for the elevated oxygen fugacity recorded by Mariana arc basalts and that slab fluids are potentially very oxidized.
“It's hard to speak up”: Lessons learned from engaging U.S. white college men in conversations on racism

Objective: This position paper draws on findings from the Straight White College Men Project, a qualitative study with heterosexual white college male participants across college campuses in the United States. The purpose of the larger project was to explore and understand how participants perceived institutional and community diversity issues; how they conceptualized their own privileges; and how they articulated their own responsibility to engage in social change. Thus, this paper delivers “lessons learned” from engaging white men in conversations on racism and to provide recommendations for medical educators in the U.S. and in Europe. Methods: Following purposeful sampling methods using expert nominators, data were collected in phenomenological focus groups at 10 U.S. 4-year universities. Focus groups included 3 to 8 participants and were 60 to 90 minutes in length. Analysis included open and axial coding and two themes emerged from a single question focusing on students’ potential dissent of racist family or peer comments. Results: Participants struggled articulating how and in what contexts they would challenge family members or friends on inappropriate language or behavior. Reasons for their reticence included struggling to confront parents, not wanting to ruin male friendships, or jeopardizing being ousted by the male peer group. Conclusion: Educators must find ways to help male university students explore their privileges and proclivity to engage in oppressive behaviors. Men also need to understand how their inactions perpetuate systemic oppression and create environments in which minoritized individuals cannot thrive. Recommendations for medical school educators are provided.
Millimeter Wave Band Massive Antenna with MDMA System used in 5G Cellular System

: Mobile communications toward the fifth generation (5G) have been popularly new technology used in coming years.demands from 5G areboth high system capacity and high data rate. A novel multiple access schemes based on millimeter wave transmission and massive antennas at a base station (BS), named multipath division multiple access (MDMA), and is proposed in this paper to be a future 5G possible solution. MDMA is defined here as a method to use massive antennas at BS to achieve a processing gain to suppress multiple access interference (MAI) in cellular mobile radio system. The processing gain is obtained by implementing RAKE receivers at BS. The system concept is also demonstrated by computer simulations. Moreover, it has been shown through simple but crucial analysis that the system capacity and the aggregated data throughput could be boosted up to a considerable level.
Effect of different nutritional basal media culture on in vitro development of Arbutus unedo L

Strawberry tree, Arbutus unedo L. , is a species widely represented in the Mediterranean climates of southern Europe, being a very economically, medical, and ecological interesting species, been known to withstand some hard climate conditions. The aim of this study was to evaluate the A. unedo sensibility according to different nutritional basal media culture in in vitro conditions. Based on it, three different basal media were tested: Murashige and Skoog (MS), Woody Plant Medium (WPM) and Driver and Kuniyuki (DKW), with the respective vitamin composition. The culture media were supplemented with 4.44 μM 6-Benzylaminopurine (BAP) and 30gL sucrose, with pH adjusted to 5.6 before autoclaving. Biometrics characteristics were evaluated (number of shoots, longest shoot length and multiplication factor) on three in vitro cultivation cycles (with 30 days each). None of the variables presented significant differences, regardless the nutritional basal media used. It was also noticed, based on visual analysis of leaves, no indicative of nutritional deficiency (absence) or nutritional toxicity (excess). These results indicate that A. unedo in vitro performance is quite independent of the nutritional basal media culture used. These results confirm that this species is very resilient and with a high plasticity in terms of adaptability to different nutritional composition. Therefore, based on these results, is possible to state that A. unedo is not responsive to the nutritional basal media used during in vitro development and then, the efforts to get development improvement should be focused on finding the more appropriate growth regulators combination. Moreover, finding better adjust of some physical parameters applied on in vitro growth condition for this species could improve its performance (light, temperature and photoperiod).