Miracle-dz/UniFAR-FTUs huggingface dataset:
INTERACTION BETWEEN COMT AND BDNF VARIANTS INFLUENCES OBSESSIVE-COMPULSIVE-RELATED DYSFUNCTIONAL

Cognitive models emphasize the importance of dysfunctional beliefs as overimportance/need to control thoughts, perfectionism, intolerance of uncertainty, responsibility, and overestimation of threat in Obsessive-Compulsive Disorder (OCD). Twin studies suggest that these beliefs are significantly heritable, but candidate genes associated with them have not been analyzed. We genotyped the Val158Met in the COMT gene and Val66Met variant in the BDNF gene in 141 OCD patients and analyzed their single and interactive effects on the Obsessive Beliefs Questionnaire (OBQ-44). Variability in dysfunctional beliefs was not affected by the COMT or BDNF genotype in isolation, but we detected a significant COMT x BDNF interaction effect on responsibility/overestimation of threat and overimportance/need to control thoughts scores. Subjects with the BDNF Met-present and the COMT Met-present genotype showed higher scores on responsibility/overestimation of threat. An interaction between dopaminergic and neurotrophic functional gene variants may influence dysfunctional beliefs hypothesized to contribute to the development of OCD.
Talent Management-Fad or Future ? Beyond the Concept of Talent Management

The authors of this thesis have found that, during the last years, the world has witnessed a dramatic explosion of articles and books about the concept Talent Management. These books and articles, all emphasise the urgency for companies to adopt the concept and the devastating consequences if they don’t. The concept is by many researchers seen to be the top issue and, the latest trend within Human Resource Management. Nevertheless, throughout the history of the personnel profession the world has witnessed several different concepts such as Personnel Management, Human Resource Management, and Strategic Human Resource Management and several researches have claimed that these concepts describes the same thing. Some researchers have argued that the different concept instead represent a continuous rhetoric struggle by HR professionals to enhance their legitimacy and status by becoming more business oriented and demonstrate that employees indeed can make a difference in distinguishing successful organizations from others. The purpose of this thesis was to investigate the underlying reasoning and logic to why companies adopt talent management and explore what the concept represents in terms of new knowledge. By comparing traditional theories of HRM and HR planning with normative literature and interviews on Talent Management the authors have found that the concept does not represent any new and distinctive knowledge, but rather can be considered as an effort to repackage old ideas and techniques with a new label. The authors of this thesis believe that Talent Management is another illustration of the struggle by HR professionals to enhance their legitimacy and status in their organization.
QBO Influence on MJO Convection in a Numerical Weather Prediction Model

A series of observational studies have shown that the MaddenJulian Oscillation (MJO) in boreal winter is significantly modulated by the Quasi-Biennial Oscillation (QBO). The MJO becomes anomalously strong during the easterly QBO (EQBO) winters but weaken during the westerly QBO (WQBO) winters. In this study, the causal relationship is tested by integrating the Weather Research and Forecasting (WRF) model with varying lateral boundary conditions. The MJO event on December 2007, which was in the EQBO winter, is chosen as a reference case. The control ensemble-mean experiment (EQBO run) qualitatively reproduces the observed MJO. When the lateral boundary conditions are switched with those for the WQBO winter (WQBO run), the MJO event becomes weaker than the EQBO run with a pronounced weakening over the Maritime Continent. All eight ensemble members exhibit a smaller amount of precipitation over the Maritime Continent in the WQBO run than in the EQBO run. This result hints at a causal relationship in which the MJO strength is likely modulated by the QBO. The possible mechanism is briefly discussed.
Axillary Artery Diameter Measurement using Wiener Filtered Smoothing Technique

-- The axillary brachial plexus nerve block provides excellent surgical anesthesia for the elbow, forearm, and hand. By using the ultrasound scanning technique, researchers can identify the location of the axillary artery during the surgery and perform clinical analysis on physiological effect of nerve block by measuring the diameter of the axillary artery. However, manual assessment and measurement of the ultrasound image can be inaccurate, restricted to intra and inter observer variability and time consuming. The objective of this paper is to increase the resolution of the image to propose a precise axillary artery diameter measurement method by wiener filter. The resolution of images are compared by using Weiner, Frost and followed by anisotropic diffusion filters. Manual thresholding is applied to the image and followed by level set segmentation. The precision of the artery measurement before and after the image processing techniques is gauged by evaluating the standard deviation of the diameter parameters. The findings show that the measured diameter of processed image has smaller standard deviation of 0.019 mm as compared with original image of 0.045 mm. The study concludes that the processed image can clearly indicate the location of the axillary artery.
Efficiency of Radiolabeling Eggs Before and After Microwave Cooking for Gastric Emptying Scintigraphy Studies

The accuracy and reproducibility of nuclear medicine gastric emptying scintigraphy (GES) require strict adherence to the Society of Nuclear Medicine and Molecular Imaging standardized protocol, which contains precise instructions for meal ingredients and preparation. Previous research demonstrated that many laboratories were using whole eggs in the test meal as opposed to the guideline-recommended liquid egg whites and that some laboratories were attempting to radiolabel the egg by adding the radiotracer after cooking. This study aimed to document the labeling efficiency of 99mTc-sulfur colloid (SC) added to whole eggs before and after microwave cooking. Methods: Whole eggs were mixed with 99mTc-SC before and after microwave cooking. The radiolabeling stability of the eggs was tested after 2 and 4 h of incubation in gastric fluid simulated using just hydrochloric acid (HCl) and using HCl with pepsin. Results: The experiment showed that no matter what the testing condition, radiolabeling by adding 99mTc-SC to whole eggs before cooking resulted in a significantly higher labeling efficiency than radiolabeling by squirting the 99mTc-SC on eggs after cooking. This finding persisted over time, with the precooking method still showing significantly higher radiolabeling at 2 and 4 h after the egg was placed in the incubation medium for both gastric fluid mediums. For simulated gastric fluid with pepsin at 2 h, the labeling was significantly higher, at 73.3%, when the radiotracer was added before cooking than the 43.3% when added after cooking (P < 0.001). The results of this study further showed that when egg labeling efficiency was tested in HCl without pepsin, the labeling was less stable than when tested in HCl with pepsin. In the HCl-only medium, the labeling efficiency decreased significantly between 2 and 4 h for both radiolabeling methods. Conclusion: The results of this study demonstrated that the addition of 99mTc-SC to whole eggs after cooking resulted in considerably inferior binding of the radiotracer to the eggs and that binding deteriorated significantly over time. The study further demonstrated that the results of radiolabeling efficiency varied depending on whether HCl or HCl with pepsin was used to simulate gastric fluid. Radiolabeling stability decreased over time when HCl without pepsin was used. The findings emphasize the criticality of adhering to the standardized meal and preparation, as alternate cooking methods have different radiolabeling efficiencies.
Wound Healing Potentials of Aqueous Pineapple ( Ananas comosus ) Extract - a Preliminary Report

: The wound healing potentials of aqueous pineapple extract ( Ananas comosus ) were evaluated in eighteen (18) adult male albino rats (152±1.6g) randomized into 3 groups following a 2cm full-thickness skin incision induced on their dorsum. Group A wounds were treated twice daily with aqueous pineapple extract (APE)(n=6), B -silver sulphadiazine (SSD) (n=6) and C- phosphate buffer saline (PBS) (n=6). All wounds were evaluated conventionally with gross and histologic wound healing indices. Wound edge oedema, hyperaemia and exudation were prominent in all the groups between days 0 and 1 of the study. Wound edge oedema was, significantly less (p<0.05) on day 2 in APE (30%) compared with SSD(83%) and PBS(100%), (APE< SSD< PBS). Wound hyperaemia was markedly less, on days 2 and 3, though not significant (p > 0.05) (APE< SSD< PBS). Wound exudation was significantly less (p<0.05) on day 2 in APE compared to SSD and PBS (APE<SSD< PBS). Wound contraction was significantly higher (p<0.05) between day 2 and 3 in APE group compared with SSD and PBS groups. Marked contraction was also observed between days 4 and 6 in APE and SSD groups (SSD> APE> PBS). The histologic changes observed on day 7 and 14 showed significant (P< 0.05) amount of Type 1 collagen, blood capillary regression and wound epithelialization in the APE and SSD groups compared with PBS group. Results of this study showed that aqueous pineapple extract possesses wound healing potentials compared to silver sulphadiazine and recommended for wound management in poor resource settings of third world countries.
Arabidopsis Extra-Large G Proteins (XLGs) in phosphate homeostasis

Phosphorus, which is taken up as inorganic phosphate (Pi), is one of the most limiting nutrients for plants. To maintain Pi homeostasis, many proteins (e.g. SPX domain proteins) are involved in signalling pathways to mediate different plant responses. In addition to the canonical heterotrimeric G proteins, the Arabidopsis genome encodes three Gα-like proteins, named Extra-Large G proteins: XLG1, XLG2, and XLG3. This project study the role of XLGs in Pi homeostasis in Arabidopsis thaliana . Analysis of the shoot Pi content showed a decreased accumulation in xlg1 -2 and xlg3-2 single mutants, which is more notable in the xlg1-2 xlg3-2 double mutant. Under Pi starvation, the xlg1-2 xlg3-2 double mutant developed longer primary roots compared to wild-type plants, while the single xlg mutants were not significant different. Furthermore, all tested xlg single and double mutants showed a tendency toward increased transcript levels of phosphate starvation induced genes compared to the wild-type. Additionally, yeast two-hybrid assays showed an interaction between SPX proteins and XLG1 and XLG3. AtSPX1, a phosphate-dependent inhibitor of the MYB-type transcription factor Phosphate Starvation Response 1 (PHR1), interacts with both AtXLG1 and AtXLG3. However, AtSPX-MFS1, a vacuolar transporter that mediates phosphate storage, only interacts with AtXLG3. These results suggest that XLGs proteins may play a role in Pi homeostasis together with SPX proteins. mutant a in hypocotyl length compared to wild-type, xlg3-2 double mutant by
ASSISI Playground: A simulation tool for collective bio-hybrid system research

This paper presents ASSISI Playground , a simulator for facilitating research in the area of collective bio-hybrid systems. Its development is motivated by the speciﬁc use-case of simulating bio-hybrid societies consisting of honeybees and static robotic units called CASUs (Combined Actuator-Sensor Units). However, due to its modular design, the simulator can easily be extended to other animal species and other types of robot. The distinguishing features of the software are the ability to simulate societies consisting of hundreds of individuals in real time, behaviour of individuals implemented in Python scripts that can be easily modiﬁed and extended by the user, and the ability to directly transfer controllers from simulated to real robots. Furthermore, the simulator implements several modalities of physical interaction that are not typically provided by conventional simulation frameworks but highly relevant to bio-hybrid research, including vibrations, airﬂow and heat transfer. In the paper, we describe the simulator architecture, provide implementation details for the physical interaction modalities and present two examples which demonstrate the usability of the simulator.
Protein Kinase C- and Ca 2+ lonophore-Stimulated Production of Reactive Oxygen Species in Mechanically Dispersed Isolated Bovine Luteal Cells'

We measured the production of reactive oxygen species (ROS) using luminol-horseradish peroxidase-induced chemiluminescence in mechanically dispersed cell suspensions from bovine corpus luteum (CL). Since other cell types besides luteal cells were present in crude cell suspensions from CL, cell preparations were purified by centrifugation on Percoll. Only cell suspensions that gave no significant response when stimulated with formyl-methionyl-leucyl-phenylalanine, a potent stimulator of ROS production by phagocytes, were used routinely. Basal ROS production by purified bovine luteal cell preparations was low but could be stimulated rapidly and in a dose-dependent manner by nanomolar concentrations of the protein kinase C (PKC) activator phorbol 12-myristate 13-acetate (PMA), though only in cells purified by fractionation on Percoll. Luteal ROS responses to PMA were quenched by returning bovine erythrocytes to purified luteal cells, or by exogenous catalase or superoxide dismutase. The magnitude of the response to PMA varied markedly from one luteal cell preparation to an-other but appeared to be unrelated to the stage of the luteal phase of the CL from which the cells were prepared. The Although the inactive phorbol ester (4e-phorbol didecanoate; 4otPDD) alone had little or no effect on luteal ROS production, 4tPDD significantly potentiated the effects of submaximal concentrations of PMA in a dose-depen-dent manner. ROS production could also be stimulated by the Ca 2+ ionophore A23187. This response was rapidly abolished by treatment with EDTA or EGTA. A23187 also augmented the response to submaximal PMA levels: however, pretreatment with 4aPDD did not significantly enhance the ROS response to A23187.In conclusion, we have shown that isolated bovine luteal cell suspensions are capable of generating a marked acute ROS response triggered by activation of PKC and/or elevation of cyto- solic calcium.
Offline Handwritten Gurumukhi Numeral Recognition Using SVM and Different Feature Sets

-Isolated handwritten numerals recognition has been the subject of intensive research during last decades because it is useful in wide range of real world problems. It also provides a solution for processing large volumes of data automatically.Work has beendone in recognizing handwritten characters and numerals in manylanguages like Chinese, Arabic, Devanagari, Urdu and English.Recently there is an emerging trend in the research to recognize handwritten characters and numerals of many Indian languages and scripts. In this manuscript we have practiced the recognition of handwritten Gurumukhi numerals. We have used three different feature sets. Out of three, two feature sets are based on the output of Gabor filters one being GABM having dimensionality 210 and other being GABN with dimensionality 200.Third feature set is comprised of Gradient Features forming 200 features. The SVM classifier with RBF (Radial Basis Function) kernel is used for classification. We have obtained the 5-fold cross validation accuracy as 99.7% using third feature set consisting of 200 gradient features. On second and first feature sets recognition rates 99.53% and 99% are observed. To obtain better results pre-processing of noise removal and normalization processes before feature extraction are recommended.
Notes on diagnostic strategies in process plant environment

Copyright and moral rights for the publications made accessible in the public portal are retained by the authors and/or other copyright owners and it is a condition of accessing publications that users recognise and abide by the legal requirements associated with these rights. • Users may download and print one copy of any publication from the public portal for the purpose of private study or research. • You may not further distribute the material or use it for any profit-making activity or commercial gain • You may freely distribute the URL identifying the publication in the public portal If you believe that this document breaches copyright please contact us providing details, and we will remove access to the work immediately and investigate your claim. Downloaded from orbit.dtu. dk on: Nov 04, 2018
Most Effective Communication Management Techniques for Geographically Distributed Project Team Members

The effective project management for high quality software projects is only possible by effective communication and coordination among project team members and is a complex task when team members are geographically distributed. This research paper describes the techniques of the communication management of the data mining based and knowledge based tools and advance analytic techniques for extracting data and knowledge of social structures using email, chat and mobile and predicting the communication relationship analysis on the basis of this knowledge.
Separation of Ig Subclasses and ld-bearing Molecules by AJfinity Chromatography

Anti-idiotypic reagents (anti-Id) have been used to manipulate both idiotype (Id) expression and antigen-binding activity of immunized animals in various experimental systems (I-I0). In many studies, in vivo administration of small amounts of purified anti-Id has been shown to suppress subsequent immune responses to the immunogen (2-5). In contrast, evidence for induction of Id-positive molecules and antigen-specific cells in mice treated with anti-Id antibodies in the presence (3, 6, 8, 10) or absence (1, 7, 9) of antigen has also been reported. Attempts have been made to extend these studies to the production of anti-idiotypic antibodies directed against alloantisera and/or alloimmune cell populations (11-13) and to use these anti-Id to manipulate in vivo responses (14-15). This approach has led to variable success, in part, because of difficulties in reproducibly generating anti-Id antisera by these methods, possibly because of the heterogeneity of many anti-major histocompatibility complex (MHC) responses (13). We have therefore recently developed heterologous anti-idiotypic antisera raised against monoclonal anti-H-2K k antibodies. This approach offers the advantages of reproducibility and availability of large quantities of immunogen for anti-Id production (16). These anti-Id have previously been shown (7, 16) to detect "private" determinants restricted to the monoclonal reagent used as immunogen and expressed in low, often undetectable levels in alloantisera containing antibodies with the same H-2 reactivity. We examined the effects of in vivo administration of these anti-Id. We report the induction of both Id-positive molecules and antigen-binding activity as a result of such treatment. The genetic requirements for such responses and the effects of pretreatment with anti-Id on the expressed repertoire of anti-H-2K k antibodies induced after subsequent immunization to alloantigen are also described.
Failure Diagnosis and Prognosis of Safety Critical Systems: Applications in Aerospace Industries

Many safety-critical systems such as aircraft, space crafts, and large power plants are required to operate in a reliable and efficient working condition without any performance degradation. As a result, fault diagnosis and prognosis (FDP) is a research topic of great interest in these systems. FDP systems attempt to use historical and current data of a system, which are collected from various measurements to detect faults, diagnose the types of possible failures, predict and manage failures in advance. This thesis deals with FDP of safety-critical systems. For this purpose, two critical systems including a multifunctional spoiler (MFS) and hydro-control value system are considered, and some challenging issues from the FDP are investigated. This research work consists of three general directions, i.e., monitoring, failure diagnosis, and prognosis. The proposed FDP methods are based on data-driven and model-based approaches. The main aim of the data-driven methods is to utilize measurement data from the system and forecast the remaining useful life (RUL) of the faulty components accurately and efficiently. In this regard, two different methods are developed. A modular FDP method based on divide and conquer strategy is presented for MFS system. The modular structure contains three components:1) fault diagnosis unit, 2) failure parameter estimation unit and 3) RUL unit. The fault diagnosis unit identifies types of faults based on an integration of neural network (NN) method and discrete wavelet transform (DWT) technique. Failure parameter estimation unit observes the failure parameter via a distributed neural network. Afterward, the RUL of the system is predicted by an adaptive Bayesian method. In another work, an innovative data-driven FDP method is developed for hydro-control valve systems. The idea is to use redundancy in multi-sensor data information and enhance the perfor-
POST-ENDODONTIC PAIN REDUCTION AFTER ONE AND TWO-VISITS ROOT CANAL TREATMENT IN TEETH WITH NECROTIC PULPS AND APICAL PERIODONTITIS WITH 3 PROTOCOLS OF IRRIGATION

Objective: The aim of this clinical trial was to assess whether controlled irrigation with three cryotherapy protocols with different temperature would result in a reduced of post-endodontic pain after one-visit and two visits root canal treatment in teeth with necrotic pulps. The null hypothesis was that there would be no difference between the control group and cryotherapy groups in terms of post-endodontic pain. Materials and Methods: Two hundred and forty patients aged 18-65 years were treated with three cryotherapy protocols with different temperature after one-visit and two visits root canal treatment detected with only necrotic pulps. All canals were clean and shaped with Reciproc instruments. Final irrigation with cold (6 o C, 2.5 o C, and room temperature) 17% EDTA and 10 mL cold saline solution. Results: No statistically relevant modification (p > .05) between the control group and group A were encountered concerning level or period of pain. There was no statistically relevant difference (p> .05) among Group A and CG compared with Group B. Group B showed less pain than the rest of the groups. Cryotherapy protocols used in the two experimental groups can help dentists to manage pain in root canal treatments with vital pulps. Conclusion: The methodology in both selecting the participants in the study and analyzing the data in this randomized clinical trial permitted us to conclude that cryotherapy aids clinical procedures to clean and shape the canals in order to reduce the occurrence of post-endodontic pain and the need for a prescription in patients with a diagnosis of vital pulp.
The mountaineer's method for peak detection in photoplethysmographic signals

Several efforts have been made to develop algorithms for accurate peak detection in photoplethysmographic (PPG) signals. Most of those algorithms have been specifically conceived to perform under high motion artifact and baseline drift conditions. However, little has been done regarding peak detection in low-amplitude PPG signals. In an attempt to address this issue, a simple and real-time peak detection algorithm for PPG signals was proposed. In comparison with two other well-established peak detection algorithms, the proposed method was able to achieve over than 98% sensitivity and less than 3% failed detection rate, even when the amplitude of the PPG signal dropped to 0.2 V. Still, further work is needed to improve its robustness to motion artifacts.