Miracle-dz/UniFAR-FTUs huggingface dataset:
Measuring the Specific Psychopathology of Eating Disorder Patients

Cooper and Fairburn's Eating Disorder Examination (EDE) is a semi-structured interview designed to assess the specific psychopathology of eating disorder subjects. It was employed in a study of 116 Sydney patients for 2 purposes: first, to determine its usefulness in an Australian context; and second, to compare patients with anorexia nervosa, bulimia and atypical eating disorder. The instrument appears to be quite appropriate for studies in Australia. With respect to the second aim, the results emphasize the essential similarity in psychopathology between the three diagnostic groups. The relevance of this latter finding to the categorisation of eating disorders in the DSM-IV proposals is discussed.
Identification of genetic elements from A. orientalis contributing to triphenylmethane decolorization

An Amycolatopsis species isolate was found to break down two structurally distinct dyes, one of which is crystal violet. This study aimed to identify the genes involved in triphenylmethane dye biodegradation. A library was constructed and four genes were isolated and identified as3-deoxy-7-phosphoheptulonate synthase, N5, N10- methylenetetrahydro methanopterin reductase, polycystic kidney domain I and glucose/sorbosone dehydrogenase. Gene expression was conducted in the host species Streptomyces lividans. The synergistic action of the segenes led to complete crystal violet decolorization. Additionally, the activity of these genes was tested in two other bacterial species, namely Mycobacterium sp. and Rhodococcus sp. The range of dye classes decolorized was extended in both species, showing that the segenes adopted novel functional potentials within these hosts.
Modelling the Impact of Airline Service Quality and Marketing Variables on Passengers’ Future Behavioural Intentions

Abstract This article investigates how perceived price, airline service quality, perceived value, passenger satisfaction and airline image determine passengers’ future behavioural intentions. To test the conceptual framework, structural equation modelling using a maximum likelihood estimator was applied to data collected from Australian international air passengers. It was found that there were significant relationships between the variables except for three paths. The three insignificant paths were the relationship between ‘perceived price and passenger satisfaction’, ‘service quality and airline image’ and ‘perceived value and airline image’. Perceived price, perceived value, passenger satisfaction, and airline image were each found to have a direct effect on passengers’ future behavioural intentions.
Identification of optimal lung volume during high-frequency oscillatory ventilation using respiratory inductive plethysmography

Objectives First, to define the relationships between critical opening and closing pressures and oxygenating efficiency, and second, to address whether respiratory inductive plethysmography (RIP) could be used to monitor changes in thoracic volume that follow changes in mean airway pressure during high- frequency oscillatory ventilation (HFOV). Design Prospective, interventional animal study. Setting University research laboratory. Subjects Five anesthetized, paralyzed, and ventilated pigs. Interventions The animals were ventilated by using HFOV after lung injury. Pre- and post-HFOV pressure-volume curves were obtained by supersyringe. A pressure-volume curve was constructed during HFOV as mean airway pressure was increased from 10 to 40 cm H2O and then weaned back down to the minimum sustainable. Hemodynamic and oxygenation data were obtained at each data point. Measurements and Main Results RIP-derived thoracic volumes correlated with known lung volumes during supersyringe (r2 = .78, p < .00001). During HFOV, three of five animals had an identifiable critical opening pressure of the lung, and four of five had an identifiable critical closing pressure. No consistent relationship between critical opening and critical closing pressures was observed. During the weaning phase of HFOV, a relative decrease in RIP-measured volume of >10% predicted the decrease in oxygenation associated with reaching the critical closing pressure. Conclusions The ability of RIP to detect optimal lung volume during the weaning of mean airway pressure may allow clinicians to more directly monitor lung volume changes during HFOV and use the lowest possible airway pressures after lung recruitment.
OntoMetrics: Putting Metrics into Use for Ontology Evaluation

Automatically calculated metrics are needed in order to evaluate ontology quality. Otherwise, major resources are required in order to manually assess certain Quality Criteria of an ontology. While there is rule based support for the detection modelling errors and the violation of ontology modelling guidelines, there is a lack of support for calculating ontology metrics. However, metrics can serve as indicators for possible quality problems that are not covered rulebased ontology evaluation. Many metrics have been proposed that correlate for example with ontology characteristics like Readability, Adaptability, and Reusability. However, there is a lack of tool support. OntoMetrics provides free access to metric definition and calculation. Furthermore it fosters the development of knowledge regarding the application of Ontology Metrics. This paper provides theoretical background and usage scenarios for the OntoMetrics on-line platform.
Compound C induces protective autophagy in cancer cells through AMPK inhibition-independent blockade of Akt/mTOR pathway

In the present study, we report that compound C, an inhibitor of a key intracellular energy sensor AMP-activated protein kinase (AMPK), can induce autophagy in cancer cells. The induction of autophagy in U251 human glioma cell line was demonstrated by acridine orange staining of intracellular acidic vesicles, Beclin 1 induction, p62 decrease and conversion of LC3-I to autophagosome-associated LC3-II in the presence of proteolysis inhibitors. The presence of autophagosome-like vesicles was confirmed by transmission electron microscopy. Compound C-mediated inhibition of AMPK and raptor in U251 cells was associated with paradoxical decrease in phosphorylation of AMPK/raptor-repressed mTOR, a major negative regulator of autophagy, and its downstream target p70S6K. The phosphorylation of an mTOR activator Akt and the PI3K-activating kinase Src was also impaired in compound C-treated cells. The siRNA-mediated AMPK silencing did not reduce the activity of the Akt/mTOR/p70S6K pathway and AMPK activators metformin and AIC AR failed to block compound C-induced autophagy. Autophagy inhibitors bafilomycin and chloroquine significantly increased the cytotoxicity of compound C towards U251 cells, as confirmed by increase in lactate dehydrogenase release, DNA fragmentation and caspase-3 activation. Similar effects of compound C were also observed in C6 rat glioma, L929 mouse fibrosarcoma and B16 mouse melanoma cell lines. Since compound C has previously been reported to suppress AMPK-dependent autophagy in different cell types, our findings suggest that the effects of compound C on autophagy might be dose-, cell type- and/or context-dependent. By demonstrating the ability of compound C to induce autophagic response in cancer cells via AMPK inhibition-independent downregulation of Akt/mTOR pathway, our results warrant caution when using compound C to inhibit AMPK-dependent cellular responses, but also support further exploration of compound C and related molecules as potential anticancer agents.
Research on query-based automatic summarization of webpage

In order to overcome the shortcomings of traditional automatic summarization technologies, this paper proposes a novel automatic method for webpage summarization based on user's query. This method can be divided into the following steps. First, a HTML document is segmented into different topic blocks. Second, the weight of every sentence in a topic block is calculated in view of query keywords. Finally, several important sentences are dynamically extracted to compose the digest according to expected compression ratio with the improved Maximal Marginal Relevance method, which can remove redundant information in summary. The experiment results show that the proposed method can increase the digest coverage to the original document and improve the performance of information retrieval efficiently.
Control of calcium release and the effect of ryanodine in skinned muscle fibres of the toad.

1. Skinned muscle fibres from the toad were used to investigate the roles of T‐system membrane potential and Ca2+ in controlling the calcium release channels of the sarcoplasmic reticulum (SR). 2. Replacement of K+ in the bathing solution with Na+ produced a large contraction which could last for 30 s or more under certain circumstances. This prolonged contraction could be quickly and completely terminated by repolarizing the fibre in the K+ solution and then immediately re‐initiated by returning to the Na+ solution. These data indicate that the membrane potential tightly controlled the substantial and prolonged release of calcium. 3. T‐system depolarization in the presence of 10 mM‐free EGTA (pCa greater than 9) markedly depleted the SR of Ca2+. This implies that depolarization of the T‐system can still trigger substantial release of Ca2+ from the SR even when the myoplasmic [Ca2+] is very low and very heavily buffered by EGTA. 4. When the SR was heavily loaded with Ca2+, substitution of a weakly buffered high [Ca2+] solution (pCa 5.4, 50 microM‐EGTA) could produce a small to moderate, transient contraction taking between 3 and 12 s to reach a peak and lasting 30 s or more. 5. This contraction may be produced at least partly by ‘calcium‐induced calcium release’ as ruthenium red (2 microM) completely blocked the responses. Moreover, repeated substitutions produced successively smaller responses in parallel with the ‘run‐down’ of the depolarization‐induced contractions. 6. Depolarization could always produce an additional large and fast response at any stage during a ‘Ca2(+)‐induced’ response. 7. In the presence of 25 microM‐ryanodine, the rapid contraction produced by T‐system depolarization was prolonged and could not be stopped by repolarization. During and after this contraction no depolarizing stimulus could induce a further contraction, even though in some fibres addition of 30 mM‐caffeine produced a maximum response which indicated that there was still a substantial amount of calcium in the SR. 8. At pCa 6.4, 25 microM‐ryanodine could itself induce a substantial slow contracture in a normally polarized fibre within 30‐60 s, after which little or no response could be induced by T‐system depolarization. At higher concentrations (25 microM) ryanodine produced a near‐maximum contraction in only a few seconds. (ABSTRACT TRUNCATED AT 400 WORDS)
Nutrition and health. The issue is not food, nor nutrients, so much as processing

Orthodox teaching and practice on nutrition and health almost always focuses on nutrients, or else on foods and drinks. Thus, diets that are high in folate and in green leafy vegetables are recommended, whereas diets high in saturated fat and in full-fat milk and other dairy products are not recommended. Food guides such as the US Food Guide Pyramid are designed to encourage consumption of healthier foods, by which is usually meant those higher in vitamins, minerals and other nutrients seen as desirable. What is generally overlooked in such approaches, which currently dominate official and other authoritative information and education programmes, and also food and nutrition public health policies, is food processing. It is now generally acknowledged that the current pandemic of obesity and related chronic diseases has as one of its important causes increased consumption of convenience including pre-prepared foods. However, the issue of food processing is largely ignored or minimised in education and information about food, nutrition and health, and also in public health policies. A short commentary cannot be comprehensive, and a general proposal such as that made here is bound to have some problems and exceptions. Also, the social, cultural, economic and environmental consequences of food processing are not discussed here. Readers’ comments and queries are invited.
Correlations Among Electrogastrogram, Gastric Dysmotility, and Duodenal Dysmotility in Patients With Functional Dyspepsia

Aim The aim of this study was to assess gastric slow waves, antral and duodenal motility simultaneously, and determine the correlation among all these measures in patients with functional dyspepsia. Methods Thirty-one patients with functional dyspepsia were assessed for severity of upper gastrointestinal symptoms with the electrogastrography (EGG) and antroduodenal manometry. The EGG and manometry were recorded for 3 to 4 hours in the fasting state and for 2 hours after a solid meal. Computerized spectral analysis methods were used to compute various EGG parameters. Results The EGG was abnormal in 71.0% of patients. The abnormalities included normal slow waves lower than 70% in the fasting state (51.6% of patients) and in the fed state (48.4% of patients), a decrease in dominant power in 28.9% of patients. Antral motility was abnormal in 80.6% of patients and duodenal motility was abnormal in 74.2% of patients. For the EGG and antral motility, 19 of 31 patients had both abnormal EGG and abnormal antral motility; 2 of 31 patients had both normal EGG and normal antral motility. For the EGG and duodenal motility, these values were 16/31 and 2/31, respectively. By both EGG and antroduodenal manometry, abnormal gastric motor function was found in 93.5% of patients. However, quantitative one-to-one correlation between any of the EGG parameters and the antroduodenal dysmotility was not noted. The patients showed high symptom scores particularly to upper abdominal pain, nausea, and belch. No one-to-one correlation was noted between the symptom scores and any of the EGG or motility parameters. Conclusions More than two-thirds of patients with functional dyspepsia have abnormalities in the EGG and antral/duodenal motility. The sensitivity of these 2 different methods is essentially the same. EGG and antroduodenal manometry can complement each other in demonstrating gastric motor dysfunction in patients with functional dyspepsia.
Improved Direct Power Control of Doubly-Fed Induction Generator Based Wind Energy System

This paper proposes an improved constant switching frequency direct power control (CSFDPC) strategy for doubly-fed induction generator (DFIG) based wind energy generation systems. Unlike the conventional vector control scheme which is based on rotor current decoupling control, the proposed CSFDPC strategy directly calculates the rotor voltage within each fixed sampling period to reduce the stator active and reactive power errors. Compared to the look-up-table based DPC strategy, constant switching frequency of the rotor side converter is achieved so as to ease the design of the converter and harmonic filter. In order to provide precise stator active and reactive power control and to reduce the steady-state power errors, several compensation strategies are introduced. Simulation results for a 2MW DFIG system are provided to demonstrate the effectiveness and the robustness of the proposed control strategy during variations of active and reactive power and rotor speed.
Public Stigma Associated with Dementia in a Chinese‐American Immigrant Population

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Pyramidal horn antenna for ground penetrating radar application

In this contribution, pyramidal horn antenna design and simulation of real-world scenario of antenna in mine detection using PAM-CEM tool has been presented. The designed horn antenna has been simulated to get scattering parameters which is also tested in lab giving satisfactory results. The same antenna has been fabricated and tested for its characteristics. As a second part of the work, A-scans are generated using Vector Network Analyzer (VNA)for the detection of metallic and non-metallic objects. Three different scenarios with different targets are considered for testing of antenna in Ground Penetrating Radar (GPR) environment and A-scans are obtained. B-scan is also generated by collecting multiple A-scans.
Myeloma cell expression of 10 candidate genes for osteolytic bone disease. Only overexpression of DKK1 correlates with clinical bone involvement at diagnosis

Osteolytic bone disease (OBD) in multiple myeloma (MM) is caused by interactions between MM cells and the bone marrow microenvironment and is characterized by increased osteoclastic bone resorption and decreased osteoblastic bone formation. Recently, the role of osteoblast inhibition has come into focus, especially the possible role of overexpression of DKK1, an inhibitor of the Wnt signalling pathway. Further, CKS2, PSME2 and DHFR have also been reported as candidate genes for OBD. We studied the gene expression by quantitative reverse transcription polymerase chain reaction of TNFSF11 (RANKL), TNFSF11A (RANK), TNFRSF11B (OPG), CCL3 (MIP1A), CCL4 (MIP1B), PTHR1 (PTHrp), DKK1, CKS2, PSME2 and DHFR in purified, immunophenotypic FACS‐sorted plasma cells from 171 newly diagnosed MM patients, 20 patients with monoclonal gammopathy of undetermined significance and 12 controls. The gene expressions of the analysed genes were correlated with radiographically assessed OBD. Only overexpression of DKK1 was correlated to the degree of OBD. Myeloma cells did not express TNFSF11A, TNFSF11, or TNFRSF11B, and very rarely expressed CCL3 and PTHR11. CCL4, CKS2, PSME2 and DHFR were variably expressed, but the expression of these genes showed no correlation with OBD. In contrast, loss of PSME2 expression in MM plasma cells was significantly correlated with OBD.
A parametric study of genetic algorithms for pixelated antenna design

To reduce the design cycle of antenna development, pixelated antenna design becomes a very important approach. The success of pixelated antenna design relies on understanding the effect of genetic operators and learning thoroughly how to set the level of parameters. The aim of this paper is to present a numerical study for designing genetic algorithms (GAs) that perform well and robust on pixelated-antenna-design problems. We show that for a GA using orthogonal arrays as initialization condition we can enhance the capability of exploring the solution domain. On the other hand, the important guiding features to generate a successful design, such as the “sweet spot” of GA parameters and population sizing, are illustrated in this paper.
A discussion of the transition metals on the basis of quantum mechanics

The magnetic susceptibilities and electrical conductivities of cobalt, nickel and palladium and of their alloys with copper, silver and gold are discussed on the basis of the quantum theory of metals. It is shown that the number of electrons in the outermost s state must be about 0.6 per atom in the transition metals and one in the noble metals; certain magnetic properties of the alloys are explained on the basis of this fact. A quantum-mechanical explanation of the relatively high resistance of the transition metals is given and is shown to be supported by measurements of the resistance of alloys.
Robust Time Optimal Obstacle Avoidance Problem for Constrained Discrete Time Systems

This paper presents algorithms for the computation of the set of states that can be robustly steered in a finite number of steps via state feedback control to a given target set while avoiding pre–specified zones or obstacles. The paper therefore extends standard results in (robust) time optimal control. A general procedure is given for the case when the system is discrete-time, nonlinear and time-invariant, and subject to constraints on the state and input. Furthermore, the paper shows how the necessary set computations may be performed using polyhedral algebra, linear programming and computational geometry software, when the system is piecewise affine with additive state disturbances.
Applying DeLone and McLean Information System Model to Online Consumer Behavior in China

In order to examine whether DeLone and McLean Information System (IS) model can be used in explaining online consumer behavior in China, a model is developed based on it from consumer’s perception perspective. Considering Chinese consumer’s risk-averse character, a risk factor is added. In empirical analysis, the university students are used as samples and Structure Equation Modeling (SEM) is used as analysis method with SPSS15.0 and Lisrel8.70. Relationships between various factors in DeLone and McLean IS model and perceived risk are all verified except that between use intention and perceived net benefit. The findings show that our model can interpret Chinese consumers’ online behavior. Finally the corresponding suggestions based on the findings are provided to the operation of retail websites.
Prediction of cost and performance of cloud applications

The pay-per-use business model is one of the key factors for the success of the cloud computing paradigm: resources are acquired only when needed and charged on the basis of their actual usage. The execution of applications in the cloud implies costs that depend on the usage of the leased resources and on the resource pricing model adopted by the providers. This paper presents a technique to evaluate the tradeoff between costs and performance of cloud applications through the use of benchmarks and simulation. Given a mOSAIC cloud application, it is possible to predict performance indexes and resource consumption under generic workloads. This makes it possible to choose the deployment on the resources of the provider that guarantees the desired performance levels and minimises the costs for executing the application.