Miracle-dz/UniFAR-FTUs huggingface dataset:
Psychosocial Adaptation to Visual Impairment

Acquired visual impairment evoked several psychological reactions. A person’s adapta- tion to these reactions and their associated characteristics such as degree of vision loss, membership of a specific demographic, and impact on personality had been investi - gated. Socio-environmental variables also had an impact on psychological adjustment, and adaptation to vision loss had been explained using psychoanalytic models and stage models. Previous research had thus developed adjustment models incorporating the variables of anxiety, depression, self-esteem, self-efficacy, locus of control, acceptance of disability, attitudes toward blindness, and attributional style, among other influences. However, effective types of treatment based on these variables had not been empirically demonstrated. While grief work had been commonly used in intervention strategies, and there was now more information available about group counseling in this field, their evaluation had been insufficient. As an alternative, we implemented a structured group counseling program to decrease psychological distress in adults with visual impairment. The results indicated that participants who engaged in individual therapy in addition to group counseling showed decreased depression, fatigue, and confusion, and a sig - nificantly improved acceptance of their disability. The group counseling combined with individual cognitive therapy could be the effective tool to improve social influences and internal self of the person with visual impairment. recreation, and computer training. The programs were held 5 days per week, and the course ran for 6 months. The results indicated that participants in skills training alone ( n = 32) improved significantly in acceptance and attribution style, while also showing a trend of improvement in tension anxiety and self-esteem. However, participants with high levels of psychological distress (who indicated a T -score of Profile of Mood States Test over 60, n = 10) did not show any such improvements. Nevertheless, highly distressed participants that participated in group counseling ( n = 18) showed significant improvement in their attitudes toward visual impairment and reported decreased anxiety. Moreover, par ticipants that chose to engage in individual therapy in addition to group counseling ( n = 9) also showed a decrease in depressive mood, fatigue, and confusion, as well as significantly increased acceptance of their visual disability.
Drift and mixing under the ocean surface: A coherent one-dimensional description with application to unstratified conditions

[1] Waves have many effects on near-surface dynamics: Breaking waves enhance mixing, waves are associated with a Lagrangian mean drift (the Stokes drift), waves act on the mean flow by creating Langmuir circulations and a return flow opposite to the Stokes drift, and, last but not least, waves modify the atmospheric surface roughness. A realistic ocean model is proposed to embrace all these aspects, focusing on near-surface mixing and surface drift associated with the wind and generated waves. The model is based on the generalized Lagrangian mean that separates the momentum into a wave pseudomomentum and a quasi-Eulerian momentum. A wave spectrum with a reasonably high frequency range is used to compute the Stokes drift. A turbulent closure scheme based on a single evolution equation for the turbulent kinetic energy includes the mixing due to breaking wave effects and wave-turbulence interactions. The roughness length of the closure scheme is adjusted using observations of turbulent kinetic energy near the surface. The model is applied to unstratified and horizontally uniform conditions, showing good agreement with observations of strongly mixed quasi-Eulerian currents near the surface when waves are developed. Model results suggest that a strong surface shear persists in the drift current because of the Stokes drift contribution. In the present model the surface drift only reaches 1.5% of the wind speed. It is argued that stratification and the properties of drifting objects may lead to a supplementary drift as large as 1% of the wind speed.
Association between early parental deprivation and cellular immune function among adults in rural Fujian, China.

This study investigated the role of childhood parental deprivation in the association between quality of life (QOL) and the Epstein-Barr virus (EBV) antibody titer, a marker of cellular immune functioning, using data from 734 adults living in seven communities in rural Fujian, China. Parental deprivation was defined if either of their parents had died, divorced, or left them for migratory work for more than 1 year before they turned (a) 16 years of age (childhood and adolescence), or (b) 3 years of age (early childhood). A mixed-effects regression analysis with a random effects model revealed that parental deprivation during early childhood was positively associated with the EBV antibody titer (coefficient = 0.33, p = 0.007), whereas parental deprivation during the first 16 years was not. Further analysis incorporating an interaction term between QOL and parental deprivation revealed a significant interaction between QOL and parental deprivation during early childhood; a significant association between QOL and the EBV antibody titer was found only among those who reported parental deprivation during early childhood. This study suggests that parental deprivation during the period of immune system development may be linked with physiological responses to stressors later in life.
EFFECT OF DIFFERENT GROWING MEDIAS MIXTURE ON GERMINATION AND SEEDLINGS GROWTH OF MANGO (MANGIFERA INDICA L.) CULTIVARS UNDER NET HOUSE CONDITIONS

Mango is important fruit crop in India. If grow scientifically it is the highest remunerative fruit crop. Therefore present investigation was undertaken to increased better germination and growth of mango cultivars. The present investigation entitled “Effect of different growing medias mixture on germination and seedlings growth of mango (Mangifera indica L.) cultivars under net house conditions”. From the foregoing discussion it can be concluded that among the different growing medias M 3 i.e. Soil + Sand + Farm Yard Manure (2: 1: 1) is found to be the most effective for better germination of mango stone as well as growth of mango seedlings (height, number of leaves, length of root and shoot, stem girth, fresh and dry weight of seedlings as well as survival per cent of seedlings). Similarly among the cultivars tried, V 3 (LSM–12-Master Royal) found better for the above parameters. Therefore, the combination of M3V3 (Soil + Sand + Farm Yard Manure (2: 1: 1) + LSM-12-Master royal) found most suitable for growing of mango stone for rootstock purpose under nursery conditions.
Design and evaluation of a multi-epitope assembly peptide vaccine against Acinetobacter baumannii infection in mice.

AIM To design a multi-epitope assembly peptide (MEP) of Acinetobacter baumannii and evaluate its immunogenicity and protective immunity in Balb/c mice. METHODS The T- and B-cell epitopes of outer membrane proteins FilF and NucAb from A. baumannii were predicted and identified by using bioinformatics software and immunological tests. Peptides with predicted high adhesin probability from A. baumannii Ata protein was used as the backbone, two B-cell epitopes and one CD4+ T-cell epitope from FilF were linked to the N-terminal of the backbone, and two B-cell epitopes and one CD4+ T-cell epitope from NucAb were linked to the C-terminal of the backbone to construct the MEP. The gene of the MEP was expressed in E. coli BL21, and its immunogenicity and protective efficacy were evaluated in Balb/c mice. RESULTS A recombinant protein with a molecular weight of about 37 kDa was successfully purified, and was identified as the recombinant multi-epitope assembly peptide (rMEP) by Western blot analysis. The animal tests showed that the rMEP was highly immunogenic and could induce high levels of IgG antibody and provide potent protection (88.9%) against lethal doses of A. baumannii. CONCLUSIONS This is the first report of the design and study of a rMEP vaccine against A. baumannii. The results indicate that the rMEP is a promising vaccine candidate for the control of infections caused by A. baumannii.
R&D and productivity in the Indian pharmaceutical firms

Recent researches for developing countries suggest knowledge generating activates is no silver bullet for productivity growth. In this context, this paper examines the impact of R&D activities on firms’ performance for the Indian pharmaceutical industry by utilizing the data of the post reform period (1994-2006). The empirical analysis is performed in two stages. In first stage, we examine the relative productivity performance of R&D vis-a-vis non- R&D. Subsequently, we construct two empirical frameworks, namely, growth accounting and production function. Results of analysis indicate that R&D firms have productivity edge over non- R&D firms. Regression results based on the growth accounting framework suggest that R&D intensity has a positive and significant effect (15%) on TFP. The results also confirm that the performance of foreign firms operating in the industry is more sensitive towards R&D than the local firms. Furthermore, the estimation results of the production function approach indicate that the output elasticity to R&D capital varies from 10% to 13%. Therefore, we support the argument that ‘manna from heaven’ impact is large and significant.
Transforming livelihood through innovative agricultural reform : an insight into the adoption of system of rice intensification (SRI) in Nepal

This study explains the ability of ground-breaking rice cultivation practice known as System of Rice Intensification (SRI). SRI is allowing Nepalese farmers to double not only the rice production but also to prove that the Nepalese farmers can adopt the agricultural technique and practices despite few obstacles on the way. SRI is high-yielding low input rice cultivation method that can increase rice yields. The result from the field visit shows that SRI can yield two-three times higher as compared to the traditional system of rice production in Morang district . The claims of improved livelihood only through SRI remain controversial due to widespread dis-adoption in some contexts. So, the study tries to understand whether SRI adoption has any impact on the welfare of villagers. The literature review shows that SRI, on the one hand, has improved the livelihood of poor farmers. On the contrary, one cannot deny the fact that SRI demands more investment i.e. more labor and machinery for large-scale cultivation. With the assistance of Agriculture service center, the study thus proceeded in three steps: qualitative questionnaire survey with the 35 farmers of Govindapur Village of Koshi Haraincha and Lohasur Village of Motipur VDC of Morang District. The second step involved the focused group discussion (FGD) among the villagers of Koshi Haraincha followed by the selected SRI Key Informant Interviews. The second and third phases of research method i.e. focused group discussion and key informant interviews test the consistency of sampling population i.e. the farmers’ response and the view gathered from the respondents of focused group discussion and key informant interview respectively. The design of this intervention allowed us to check validity and data triangulation respectively. This study explores how the adoption of SRI has influenced the livelihood assets and how the availability of the asset has influenced adoption. Thus, the underlying premise of this study is the analysis of holistic perspective of how farmers have responded to the innovative agricultural reform in Govindapur Village of Koshi Haraincha Municipality and Lohasur Village of Motipur VDC respectively. From the field study on these two villages, it can be concluded that it is the access to physical and natural resources that determines the successful adoption of SRI technique for better livelihood. Govindapur village upon good access to resources has delivered good result on SRI practice than Lohasur village which lacks access to resources.
Rituximab: A Hope for Lymphoma Patients

Rituximab is an antibody targeting the CD20 receptor protein of B-cells, the immune cell responsible for specific adaptive immune system properties. In B-cell lymphomas, where the B-cell lymphatic cells underlie the lymphoma phenotype, the use of rituximab to specifically target and destroy B-cells is a relatively recent strategy for treating lymphomas. Indeed, even recently it has been determined that classic Hodgkin’s lymphoma can be treated by a special regimen of rituximab. Rituximab had such a pronounced effect on the survival rates of certain lymphomas that the survival outcomes have fundamentally changed. These outcomes have changed to the degree that prognostic tools used to infer survival rates have had to be overhauled. The exact molecular mechanisms of rituximab activity had recently been elucidated, and although heterogeneity in lymphoma response to rituximab exists, detailed molecular studies investigating this have as a result uncovered new molecular targets, such as CD55 and CD59. The above mentioned topics, as well as the toxicity of rituximab, the use of rituximab with supplemental treatments in parallel such as histone deacetylase inhibitors, radiation therapy, and the effects of rituximab on different types of lymphomas, are all reviewed here.
Antifungal susceptibility profiles of rare ascomycetous yeasts.

OBJECTIVES To generate antifungal susceptibility patterns for Trichomonascus ciferrii (Candida ciferrii), Candida inconspicua (Torulopsis inconspicua) and Diutina rugosa species complex (Candida rugosa species complex), and to provide key parameters such as MIC50, MIC90 and tentative epidemiological cut-off values (TECOFFs). METHODS Our strain set included isolates of clinical origin: C. inconspicua (n = 168), D. rugosa species complex (n = 90) [Candida pararugosa (n = 60), D. rugosa (n = 26) and Candida mesorugosa (n = 4)], Pichia norvegensis (Candida norvegensis) (n = 15) and T. ciferrii (n = 8). Identification was performed by MALDI-TOF MS or internal transcribed spacer sequencing. Antifungal susceptibility patterns were generated for azoles, echinocandins and amphotericin B using commercial Etest and the EUCAST broth microdilution method v7.3. 1. Essential agreement (EA) was calculated for Etest and EUCAST. RESULTS C. inconspicua, C. pararugosa and P. norvegensis showed elevated azole MICs (MIC50 ≥0.06 mg/L), and D. rugosa and C. pararugosa elevated echinocandin MICs (MIC50 ≥0.06 mg/L). EA between methods was generally low (<90%); EA averaged 77.45%. TECOFFs were suggested for C. inconspicua and D. rugosa species complex. CONCLUSIONS Rare yeast species tested shared high fluconazole MICs. D. rugosa species complex displayed high echinocandin MICs, while C. inconspicua and P. norvegensis were found to have high azole MICs. Overall, the agreement between EUCAST and Etest was poor and therefore MIC values generated with Etest cannot be directly compared with EUCAST results.
The Conduct of Monetary Policy in Turkey in the Pre- and Post-crisis Period of 2001 in Comparative Perspective: a Case for Central Bank Independence

We document the role of independence for Central Bank of Republic of Turkey (CBRT) as it matters to successful implementation of monetary policy. We compare the implementation of monetary policy pre- and post-crisis periods within an empirical framework which allows us to measure the role of independence quantitatively. We estimate a Taylor rule with time varying coefficients by employing a dual extended Kalman filter. We find that the coefficient of inflation gap has increased substantially since CBRT gained de-juro independence.
The effect of exercise intensity on post-exercise lung diffusion in highly trained athletes

The purpose of this study was to determine the effect of exercise intensity on the postexercise reduction of the diffusion capacity of carbon monoxide in the lung (DLco) and whether these declines were related to reductions in arterial oxyhemoglobin saturation ( % S a 0 2 ) during exercise. Ten highly trained ( V 0 2 m a x = 66.8 ml-kg"-min") males were recruited. Subjects performed a maximal cycling test to determine V 0 2 m a x and then returned on three separate occasions to perform ten minutes of submaximal cycling at 90%, 60%, and 30% of V 0 2 m a x . During each exercise session, expired gases, HR, and % S a 0 2 were recorded every fifteen seconds. DLco was measured prior to exercise (baseline) and one-hour following each of the exercise sessions. DLco was partitioned into its components of diffusion capacity of the alveolar membrane ( D M ) and pulmonary capillary blood volume (Vc) by measuring it at two concentrations of inspired 0 2 . DLco significantly declined from baseline following each of the submaximal exercise sessions. The reductions following the 60% and 30%> exercise sessions were similar but greater than the decline that occurred following the 90% exercise test. Reductions in post-exercise DLco were accompanied by declines in DM that reached statistical significance following the 90% and 60% tests, but not after the 30% submaximal exercise session. The decline in post-exercise Vc was also greatest following the 90% submaximal session and similar for each of the 60% and 30% tests. However, Vc reductions did not reach statistical significance following any of the exercise intensities (p=0.10). % S a 0 2 during 90% submaximal exercise declined significantly greater than both the 60% and 30% exercise tests, and all were decreased below baseline. No correlation was found between the post-exercise reductions in DLco, DM, or Vc, and % S a 0 2 at any of the exercise intensities. In
Brave new Hopf algebroids and extensions of $MU$-algebras

We apply recent work of A. Lazarev which develops an obstruction theory for the existence of R-algebra structures on Rmodules, where R is a commutative S-algebra. We show that certain MU-modules have such A1 structures. Our results are often simpler to state for the related BP-modules under the currently unproved assumption that BP is a commutative Salgebra. Part of our motivation is to clarify the algebra involved in Lazarev’s work and to generalize it to other important cases. We also make explicit the fact that BP admits an MU-algebra structure as do E(n) and [ E(n), in the latter case rederiving and
Project Spraoi: a two-year longitudinal study on the effectiveness of a school-based nutrition and physical activity intervention on dietary intake, nutritional knowledge and markers of health of Irish schoolchildren

Abstract Objective: To assess the effectiveness of a nutrition and physical activity (PA) intervention on dietary intake (DI), nutritional knowledge (NK), blood pressure (BP), anthropometric measures and cardiorespiratory fitness (CRF) of schoolchildren. Design: Longitudinal study. DI, NK, BMI, waist-to-height ratio (WHtR), BP and CRF were all measured/calculated prior to (October 2014) and at the end of (June 2016) intervention delivery. Setting: Two primary schools (one intervention and one control), Cork, Ireland. Participants: Six-year-olds (n 49; mean age = 6·09 (sd 0·33) years) and 10-year-olds (n 52; mean age = 9·90 (sd 0·37) years). Results: There was a large and a moderate statistically significant difference between the change in systolic (P = 0·005, effect size (ES) = 0·165) and diastolic BP (P = 0·023, ES = 0·116), respectively, for 10-year-olds in the intervention and control groups. There was also a large statistically significant difference between the change in WHtR (P = 0·0005, ES = 0·386) and a moderate statistically significant difference between the change in NK (P = 0·027, ES = 0·107) for 10-year-olds in the intervention and control groups. There was a large statistically significant difference between the change in percentage of energy from protein in 10-year-old females (P = 0·021, ES = 0·276) in the intervention and control groups. Conclusions: Project Spraoi is Ireland’s first ever school-based intervention that has been evaluated and proven effective in improving DI, NK, WHtR and BP in older primary-school children in one intervention school.
Real-Time PCR and Its Application in Plant Disease Diagnostics

Real-time PCR is currently considered as the gold standard method for detection of plant pathogens. This technique allows the monitoring of the reaction during the amplification process by the use of a fluorescent signal that increases proportionally to the number of amplicons generated and to the number of targets present in the sample. Real-time PCR makes possible an accurate, reliable and high-throughput quantification of target pathogen DNA in various environmental samples, including hosts tissues, soil, water and air, thus opening new research opportunities for the study of diagnosis, inoculum threshold levels, and epidemiology and host pathogen interactions. Real-time PCR has versatile practical application in diagnostics of plant disease. With Real-time PCR, it is possible not only to identify and detect the presence or absence of the target pathogen, but it is also possible to quantify the amount present in the sample allowing the quantitative assessment of the number of the pathogen in the sample. Enumerating the pathogen upon detection is crucial to estimate the potential risks with respect to diseases development and provides a useful basis for diseases management decisions. Determination of the viability of a pathogen, detection of multiplexing and monitoring fungicide resistance in pathogens are other major application areas. Generally, real-time PCR technologies open increasing opportunities and a significant role in better understanding of the dynamics of plant pathogenic microorganism and, thereby allow better management of the diseases . Key words : Diagnostics, high-throughput, Pathogen, Quantification, Real-time PCR
INVESTIGATION OF BRAN LOAVES STALING FOR THE USE OF COMPLEX BAKING IMPROVER "FRESHNESS"

Elderly people’s ration must necessarily include bakery, enriched with food fibers, of yesterday baking. To improve their quality and increase their storage life, the complex bakery improver (CBI) “Freshness” was elaborated. The base of the complex improver is beer powder, combined with lecithin, enzymatic preparation Betamalt 25 FBD, carboxymethyl cellulose, ascorbic acid. According to the results of research, the optimal dose of CBI “Freshness” in the recipe of bran loaves that is 2 % of flour mass was established. The processes, connected with staling and loss of organoleptic and physical-chemical parameters of bran loaves at storage, were considered. The results of the study of free and bound water in products indicate that CBI “Freshness” use decreases osmotically bound water content that confirms the deceleration of brain loaves staling process. It was established, that CBI “Freshness” use decreases crumbling of bran loaves and increase their swelling comparing with products without it. The studies proved that at CBI “Freshness” use, the content of bisulphite bounding compounds increases comparing with a control at the expanse of the increase of the amount of substances, that form a smell at dough ripening and dough half-finished products baking. The increase of carbonyl compounds amount in bran loaves correlates with more intense flavor and smell of products, and with a crust coloration. The positive influence of CBI “Freshness” use on microbiological parameters was received that is proved by bran loaves storage life increase up to 72 hours. It was proved, that BCI “Freshness” use favors the increase of non-packed bran loaves storage life up to 72 hours at the expanse of osmotically bound water content decrease and microbiological pureness increase.