Miracle-dz/UniFAR-FTUs huggingface dataset:
Comparative Histopathological & Immunohistochemical Studies between Melatonin and Grape-Seed Extract in Treating Hepatocellular Carcinoma

High levels of alphafetoprotein (AFP) are believed to be strongly suggestive of hepatocellular carcinoma (HCC) that is the fifth most frequent cancer and the third common cause of cancer related mortality in the world. AFP was studied immunohistochemically in addition to histopathology to delight the possible cure of melatonin (mel) or grape-seed extract (GSE) in induced HCC by two different carcinogens. Seventy five male albino mice were divided into six groups; normal group (n=5), experimental control group (n=10), experimental groups (n=30) and experimental treated groups (n=30). Histopathologically, the induced HCC by diethylnitrosamine (DEN) (8 w) was faster than 2-nitropropane (NP) (14 w). Malignant foci of HCC were manifested through cords of hyperchromatic malignant cells. However melatonin ameleorated these liver changes and GSE exhibited similar role but with a lesser extent. Immunohistochemically, the expression of AFP supported the superior effect of melatonin in HCC treatment. A significant value ( 1.20±0.77 ) ( p=0.002 )was recorded post mel treatment in comparison either with HCC (2.6±1.12 ) or with GSE ( 1.87±0.74 ) (p= 0.063). In conclusion: DEN induced HCC in mice faster than 2-NP and melatonin exhibited strong cure than GSE in HCC. [Safia Mohammed Hassan. Comparative Histopathological & Immunohistochemical Studies between Melatonin and Grape-Seed Extract in Treating Hepatocellular Carcinoma. J Am Sci 2012;8(12):132-137]. (ISSN: 1545-1003). http://www.jofamericanscience. org. 20
Design and Implementation of 3-Phase 3-Level T-type Inverter with Different PWM Techniques

Multi-level inverter has a capability to handled high power with less total harmonic distortion (THD), reduced switching losses and good power quality due to which in recent year they become more popular in high power application, with Increase in the voltage level, harmonic content in output voltage waveform will decrease. Diode Clamped Multilevel Inverter (DCMLI) has a capability to increase the output voltage and performance with low switching losses, reduced voltage stress and total harmonic distortion. However, it suffers from problems of high conduction losses. T-type is used to overcome the drawbacks of DCMLI, but the high side and low side power devices of T-type inverter need to block the whole dc link voltage. The switching frequency is limited due to the high switching losses caused by the high voltage rated power devices. Generally, it is used for both low conduction losses and switching losses with high switching frequency. Simulation result of 3-phase 3-level T-type multi-level inverter can be obtained by MATLAB/ SIMULINK software multi-level inverter using different PWM technique. KeywordsMulti-level inverter(MLI); DCMLI; T-type inverter; SPWM and ISPWM techniques.
Solid Phase-Based Cross-Matching Using the Luminex Platform for Solid Organ Allo-Grafting: Rather Regression than Progress in Comparison to the ELISA-Based Precursor Procedure

Antibodies directed against HLA antigens of a given donor represent the most prominent cause for hyper-acute and acute rejections. In order to select recipients without donor-specific antibodies the complement-dependent cytotoxicity (CDC-) crossmatch was first established representing the standard procedure up to the present. Its negative pre-transplant outcome is currently regarded as the most important requirement for a successful short term kidney graft survival. As a functional assay, however, it strongly depends on the availability of isolated donor lymphocytes and in particular on their vitality. Moreover, during the last ten years several disadvantages of the CDCbased procedure have increasingly been discussed with respect to this assay’s high susceptibility to disruptive factors which frequently lead to false positive outcomes. In this context several autoimmune diseases especially of the immune complex type (type III) or pharmacological treatment of a given recipient have been shown to lead to unexpected “false-positive” outcomes of the CDC-crossmatch. As methodical alternatives for anti-HLA antibody specific cross-matching two ELISA-based procedures i) the Antibody Monitoring System (AMS-) ELISA and ii) the AbCross-ELISA were established in our tissue typing laboratory and those of some other groups. Both systems, however, were discontinued for mere commercial reasons in the years 2013 and 2016, respectively. Using the same set of diagnostic antibodies, the AMS-ELISA, now named Donor-Specific Antibodies/DSA, was afterwards again manufactured as a microbead-based array using the Luminex platform. With a view to establish the DSA-assay as the only remaining solid phase-based crossmatch system commercially available, this procedure was systematically evaluated in our laboratory. Primarily but not exclusively based on drawbacks of the evaluation software, however, 69 (32.5%) of the virtually defined crossmatch results (n=212 independent anti-HLA class I and II specifications and their corresponding DSA-assays, respectively) were classified as divergent using the DSA-assay whereas only 143 results (67.5%) were classified as accordant by this assay’s software. Referring to the chosen cohort of recipients (n=106) not less than 62 (58.4%) of them are characterized by findings which are not supported by virtual crossmatching. We here provide evidence that for various reasons the outcomes provided by the DSA-assay, in contrast to those of the AMS-ELISA as its precursor system, have critically to be challenged. We therefore conclude that modifications are urgently required to be introduced by the manufacturer in order to lead again to a system of sufficient validity usable for any laboratory’s routine diagnostics.
IoT Based Energy Efficient System for Streets

In the past 20 years, speedy urbanization leads to increase in the number of street lights. Street lights are vital factor of city as they promote security in public areas and upgrade safety for drivers, riders, and pedestrians. The old lighting systems are not reliable because of its design, defective instruments and devices. Thus, it gives rise to energy losses, frequent replacement of devices, lack of monitoring, automation, and fault diagnostics problems. So, the control and management of street lights become very difficult. At present, street lamps require manpower for manual controlling. Huge amount of electrical energy is wasted. To tackle with these problems a new deterministic model is proposed to control street intensity depending on traffic needs. Also, they make use of sodium vapour lamp which is harmful. In short, the current street lighting strategy is simple and crude, lack of humane care of the car and human. Therefore, there is an urgent need to develop a highly intelligent street lighting system. The system comprises of cost-efficient components such as Arduino Uno, Sensors, some circuits for controlling and generating energy. Our prototype will help to improve the quality of service by reducing operational cost, energy and fuel consumption, and environmental issues.
Static Hand Gesture Detection and Classification Using Contour Based Fourier Descriptor

: Hand gesture recognition is a vital task as its application ranges from human-machine interface to sign language recognition. This paper present the empirical results of static hand gesture detection based on well known technique used for shape detection using Fourier Descriptors (FDs). Fourier descriptors are important features for the classification of two-dimensional connected shapes. Further the classification is done using multiclass Support Vector Machine (SVM). The performance is evaluated on Sebstian Marcel Database and qualified to provide average classification accuracy of 93%.
Patient–Centric Secure Data Sharing Frame Work for Cloud-Based PHR Systems

: In this paper, we propose a novel patient-centric framework and a suite of mechanisms for data access control to PHRs stored in semitrusted servers. To achieve fine-grained and scalable data access control for PHRs, we leverage attribute-based encryption (ABE) techniques to encrypt each patient’s PHR file. Different from previous works in secure data outsourcing, we focus on the multiple data owner scenario, and divide the users in the PHR system into multiple security domains that greatly reduces the key management complexity for owners and users. A high degree of patient privacy is guaranteed simultaneously by exploiting multiauthority ABE. Our scheme also enables dynamic modification of access policies or file attributes, supports efficient on-demand user/attribute revocation and break-glass access under emergency scenarios. Extensive analytical and experimental results are presented which show the security, scalability, and efficiency of our proposed scheme. Currently, the only method for enforcing such policies is to employ a trusted server to store the data and mediate access control. However, if any server storing the data is compromised, then the confidentiality of the data will be compromised. In this paper we present a system for realizing complex access control on encrypted data that we call Ciphertext-Policy Attribute-Based Encryption. We develop a new methodology for utilizing the prior techniques to prove selective security for functional encryption systems as a direct ingredient in devising proofs of full security. This deepens the relationship between the selective and full security models and provides a path for transferring the best qualities of selectively secure systems to fully secure systems. In particular, we present a Ciphertext-Policy Attribute-Based Encryption scheme that is proven fully secure while matching the efficiency of the state of the art selectively secure systems.
Design and Analysis of Sub-band Coding of Speech Signal under Noisy Condition using Multirate Signal Processing

- Multirate systems are most commonly used in Digital Signal Processing applications. Systems that use more than one sampling rates in the digital signal processing are called multirate DSP. The objective is to design sub band coding system. Sub band coding is a method where the speech signal is sub divided into several frequency bands and each band is digitally encoded separately. The input speech signal spectrum is divided into frequency sub bands using a bank of finite impulse response (FIR) filter. In this project low pass and high pass finite impulse response filters are designed and implemented using different windowing techniques such as Hamming, Hanning, Blackman, Rectangular and Kaiser and the responses of the FIR filters are obtained. Finally performances are evaluated based on Signal to Noise Ratio. Comparing the results of different windows it is observed that the Blackman window provides maximum Signal to Noise Ratio values when compared to other windowing techniques. This shows that performance of the Blackman window is better and it is suitable for deigning the FIR filters.
Concurrent Radiotherapy and Cisplatin Administered Weekly versus Every Three Weeks for Definitive Treatment of Locally Advanced laryngeal Cancers

Objective: This study aimed at comparing response rate and acute toxicities, in patients with locally advanced laryngeal squamous cell carcinomas (SCC) who received definitive radiotherapy (RT) concurrent with either of two cisplatin regimens (100 mg/m 2 administered every 3 weeks or 40 mg/m 2 administered weekly). Methods: Fifty previously untreated patients with stage III or IVA cancer larynx were enrolled throughout the period between June 2013 and June 2016. Results: Of all treated patients, 46% had clinical response. Patient treated with every 3 weeks sensitization had apparent insignificant better response than those treated with weekly sensitization (p=0.538). Thirty-six (72%) patients had treatment interruption and 3 (6%) patients discontinued their planned treatment due to side effects. However, this interruption was not significant between the two arms (p=0.733). Patients treated with weekly sensitization had significantly lower leukopenia, nausea and acute renal injury (p<0.05). The median OS time was 37 vs. 29 months for every 3 weeks versus weekly treated patients with the 2-year OS rate was 72% and 64% respectively (p=0.153). The median PFS was 29 vs. 27 months with the 2-year PFS rate was 68% and 60% respectively (p=0.592). Conclusions: Concurrent chemoradiotherapy (CRT) with weekly low-dose cisplatin is a reasonable and less toxic alternative to high-dose cisplatin given every 3 weeks in the treatment of locally advanced laryngeal SCC. More studies comparing the two regimens are required, particularly in patients with cancer at specific sites who need definitive CRT. [Alaa Maria and Mohamed Sheta. Concurrent Radiotherapy and Cisplatin Administered Weekly versus Every Three Weeks for Definitive Treatment of Locally Advanced laryngeal Cancers. J Am Sci 2017;13(12):7-13]. ISSN 1545-1003 (print); ISSN 2375-7264 (online). http://www.jofamericanscience. org. 2. doi:10.7537/marsjas131217.02.
Malicious Websites Classification Based On Web Address Features

: . In Cyber security, one of the major violations of cyber laws is due to propagation of malicious web sites for exploiting legitimate users. These malicious websites exploit the vulnerabilities in users systems. Also infect them by inducing malware such as phishing etc. Hence, Cyber security is an active research area where a given Uniform Resource Locator (URL) needs to be classified as either malicious or benign. In this research work, different machine learning supervised techniques are used for detecting malicious URLs with respect to 13 rules framed based on web address features. The dataset were collected from phish tank URL (https://www.phishtank.com/). Which consists of approximately 7000 URL’s. Experimental results obtained were satisfactory where Neural Network (NN), k-Nearest Neighbor (k-NN) and Support Vector Machine (SVM) classification techniques were applied on the given dataset. The empirical results shown the accuracy of the above techniques are 81.3%, 85.1% and 87.7 % respectively.
Antisickling and Antioxidant Properties of Omega-3 Fatty Acids EPA/DHA

Results: Sodium metabisulfite increased the sickling of RBCs from 26.3±1.6 to 79.42±5.2% during 3 hours. Omega-3 fatty acids EPA/ DHA 0.2% showed the best antisickling (79.05±1.2%) and reversibility (64.82± 2.7%) rate; the best membrane stability compared to other concentrations. Omega-3 fatty acids EPA/DHA revealed an appreciable reducing power at 26.08±0.3mg FeII/100g. It also showed an inhibitory activity on free radicals of DPPH and hydroxyl radical at IC50 3.7±0.0 and 11.28±0.3mg/mL respectively.
Nine-Level Diode Clamped Asymmetric Dual Converter Based Statcom with Dc Link Voltage Control

Abstract: Static synchronous compensators (STATCOMs) provide a power-electronics-based means of embedded control of transmission-line voltage and power flows. The integration of multilevel inverter to a STATCOM can extend traditional STATCOM capabilities to two way power flow control. This paper gives an overview of multilevel dual converter based STATCOMs with a focus on achieving minimum harmonic distortion and reasonable power quality improvement. The dual converter consists of two converters with different voltages to supply/absorb reactive power to/from the grid. The controller used in the STATCOMs can balance individual dc capacitor voltages when H-bridges run with different switching patterns and have parameter variations[1]. Reduced component count, simpler layout for switches, and smaller dc-link capacitor values are the attractive features of the proposed topology over the cascaded multilevel converters[2]. In extension to this the proposed system with STATCOM is designed with nine-level diode clamped multilevel inverter with sinusoidal PWM.
Comparing sensitivity of Radial Basis Function method with Multilayer Perceptron Network and Cox Proportional Hazard Model in Survival Data

Summary Cox proportional hazard model is broadly deployed in the analysis of survival data and reliability of systems and its application is contingent upon accepting some assumptions such as appropriateness of the risk. Neural network model, obviating the need of making any specific assumption, is an appropriate substitute in predicting survival data. To compare the sensitivity of neural network models with the Cox proportional hazard model, the present study investigates the sensitivity and specificity of radial basis function method, multilayer perceptron network, and cox proportional hazard model in the survival analysis of patients with myocardial infarction. The results of the study revealed that, compared to other models, neural network models performed better and were more precise in the survival analysis of patients with myocardial infarction. Moreover, compared to the other two methods, the radial basis function method is more sensitive, specific, and precise in the survival prediction of the patients under investigation in the present study and, accordingly, it is more reliable.
A REVIEW ON RECENT ADVANCES IN ENTERIC COATING AND ENTERIC POLYMERS

Worldwide many researchers are seeking the knowledge or the advances of the enteric coating and the role of polymers. The present review focuses on the elevation of enteric coating and polymers. Enteric coated means a tablet or capsule or the other form of oral medication which is layered with a defensive coating. This coating is used to fortify the stomach from unwanted effects or detrimental effects of a medication. It is most frequently used in aspirin and other NSAIDs that are known to antagonize the stomach lining, but is also often used in medications or vitamins that need to dissolve in the small intestine and absorb properly. The main important role of enteric coating is to release the drugs after the stomach. The word enteric actually mean referring to the intestine. Most of the polymers are either man made or natural and they won’t break down below levels of pH 5.5. From a pharmacological point of view the term enteric coating is not entirely scrupulous, because the gastric resistance can also be obtained by adding enteric polymeric systems. So in order to obtain a gastro resistant drug it should have enteric coating and suitable polymers for the dosage form. Different polymers were used in enteric coating like cellulose acetate phthalate, polyvinyl acetate phthalate, hydroxyl propyl methyl cellulose. The enteric coating was done on different type of dosage forms like tablets, capsules, pellets and granules. Recently there are so many advancements in the enteric coating.
EFFECTIVENESS OF SOME FUNGICIDES APPLIED TO RICE SEED ON BLAST AND LEAF BLIGHT

This article proposes a study of the effect of various doses of fungicides in presence and in absence of Pyricularia oryzae or of Helminthosporium oryzae, on the germination of seeds, on the length of coleoptiles, roots, the lesions on coléoptiles and on duration of protection of the plants of rice, against both pathogens. Accordingly, the fungicides protection of seeds against appearances inferred by both pathogens depends on the pathogen, and the dose of the fungicide used. Besides, among tested fungicides, only tricyclazole, mancozebe and the carboxine +Thiram association are able to provoke an increase of the germination of seeds, length of coleoptiles and roots as well as a decrease of the lesions on coleoptiles for both pathogens without damaging seeds. Indeed, Tricyclazole and Carboxine + Thirame association, brought respectively to 1 g / kg and 1 ml / kg of grains, reduces to 100%(fully) the development of the necrosed hurts caused on the coleoptile by P. oryzae. Mancozébe at 2 g / kg of grains got 87 % of reduction of the disease. However, a better germination of grains and a good development of the coleoptile and the roots require 2 g / kg of Tricyclazole, 3 g / kg of Mancozebe and 3 ml / kg of the combination Carboxine + Thirame. Mancozebe at 3 g / kg protects better the coleoptile against the lesions caused by H. oryzae (94.4 %), followed by Tricyclazole at 3 g / kg (80.5 %) and Carboxine + Thirame at 3 ml / kg (72.2 %). These doses also increase the percentage of germination of grains, the length of roots and coleoptiles. The treatment of grains using 1 and 2 grammes of Tricyclazole per kilogramme of grains strongly protected the seedlings of rice for four weeks, compared to the treatment based on P. oryzae (respectively 81.3 and 89.33 % at 4th week). This fungicide, brought to 3 g / kg of grains, continues to protect plants even five weeks after the treatment (77.78 %). Concerning the helminthosporiose, Tricyclazole applied to 3 g / kg of grains reduced the disease to 77.8 % and 70.7 % respectively three and four weeks after treatment. When the tricyclazole is mixed with Mancozebe (1.5g+1.5g) the reduction reaches 100% during the 6th week for P. oryzae and 84.29% for H. oryzae.
Multi User Detection Schemes for TH PPM UWB System using LDPC Codes

In multiuser environments, multi access interference (MAI) is occurred in UWB System.To overcome above problems Multiuser Detection Schemes (MUD) are used in wireless UWB System. Channel coding is another technique to reduce the multiuser access interference (MAI). One such code is LPDC codes for robust image transmission . Proposed system employs channel coding(LDPC Codes) with MUD schemes over UWB channel with TH PPM modulation in order to reduce multi access interference and leads to capacity increase for Bio-medical image transmission which is used Telemedicine application.Telemedicine provides medical information and services using telecommunication technologies . It includes systems for remote clinical case and consultation through the use of electronic imaging equipment. This paper presents BER performance of UWB system and capacity using LDPC code over TH-PPM UWB system with MUD schemes for data/ image transmission. General Terms Performance Analysis
Aspect Identification using Topic Modeling on Drug Reviews

: Now a day in the world of internet, many studies have observed that patients are getting important and supporting information on persistent diseases and related drugs from resources such as online reviews, Web blogs, and discussion forums. Mining of information from such bulk of text is a challenging task but this information is very useful. Such information can be processed using the model called Aspect identification using topic modeling (AITM) on Drug reviews which is the proposed system. This model recognizes the aspects or topics associated with the class label of the mixture of data. The important characteristic of Aspect Identification using Topic Modeling on Drug Reviews is that it determines aspect relevant to one class only. So the chances of getting aspects of different concepts from different classes are suppressed and resulting aspects can be easily interpreted. The resulting aspects are class distinguishing means they are helpful in distinguishing a class from other. The coherent Latent Dirichlet Allocation (LDA) topic modeling algorithm is used for result extraction. Four different drugs (i.e. Citalopram, Escitalopram, Lesinopril and Simavistin) are used for analyzing experimental results of the proposed system. And the analysis shows that AITM is giving better performance than other available approaches.