Miracle-dz/UniFAR-FTUs huggingface dataset:
Age Estimation using Panoramic Radiographs by Transfer Learning.

OBJECTIVE To assess the accuracy of transfer learning models for age estimation from panoramic photographs of permanent dentition of patients with an equal sex and age distribution and provide a new method of age estimation. METHODS The panoramic photographs of 3000 patients with an equal sex and age distribution were divided into three groups: a training set (n = 2400), validation set (n = 300) and test set (n = 300). The ResNet, EffiecientNet, VggNet and DenseNet transfer learning models were trained with the training set. The models were subsequently tested using the data in the test set. The mean absolute errors were calculated and the different features extracted by the deep learning models in different age groups were visualixed. RESULTS The mean absolute error (MAE) and root mean square error (RMSE) of the optimal transfer learning model EfficientNet-B5 in the test set were 2.83 and 4.59, respectively. The dentition, maxillary sinus, mandibular body and mandibular angle all played a role in age estimation. CONCLUSION Transfer learning models can extract different features in different age groups and can be used for age estimation in panoramic radiographs.
Cmos Rf Cituits Sic] Variability And Reliability Resilient Design, Modeling, And Simulation

The work presents a novel voltage biasing design that helps the CMOS RF circuits resilient to variability and reliability. The biasing scheme provides resilience through the threshold voltage (VT) adjustment, and at the mean time it does not degrade the PA performance. Analytical equations are established for sensitivity of the resilient biasing under various scenarios. Power Amplifier (PA) and Low Noise Amplifier (LNA) are investigated case by case through modeling and experiment. PTM 65nm technology is adopted in modeling the transistors within these RF blocks. A traditional class-AB PA with resilient design is compared the same PA without such design in PTM 65nm technology. Analytical equations are established for sensitivity of the resilient biasing under various scenarios. A traditional class-AB PA with resilient design is compared the same PA without such design in PTM 65nm technology. The results show that the biasing design helps improve the robustness of the PA in terms of linear gain, P1dB, Psat, and power added efficiency (PAE). Except for post-fabrication calibration capability, the design reduces the majority performance sensitivity of PA by 50% when subjected to threshold voltage (VT) shift and 25% to electron mobility (μn) degradation. The impact of degradation mismatches is also investigated. It is observed that the accelerated aging of MOS transistor in the biasing circuit will further reduce the sensitivity of PA. In the study of LNA, a 24 GHz narrow band cascade LNA with adaptive biasing scheme under various aging rate is compared to LNA without such biasing scheme. The modeling and simulation results show that the adaptive substrate biasing reduces the sensitivity of noise figure and minimum noise figure subject to process variation and
Green liquid chromatography method for the determination of related substances present in Olopatadine HCl nasal spray formulation, robustness by design expert.

BACKGROUND Dual therapeutic nature drug mast cell stabilizer and histamine receptor antagonist Olopatadine hydrochloride (OPT) nasal spray does not have the official monograph, and no literature is not available. Eye drops monograph had the official monograph for impurities, but the determination was done in two methods. OBJECTIVE A simple and effective green liquid chromatography method to develop and validate for the related substances of OPT nasal spray formulation. METHOD 25 min gradient method was employed to separate impurities and OPT with a 1.0 mL/min flow rate using Boston green C8 (150 mm × 4.6 mm, 5 µm) HPLC column. The set wavelength and column oven temperatures were 299 nm and 30 °C, respectively. pH 3.5 phosphate buffer: acetonitrile ratio (70:30, v/v) as mobile phase and (50:50, v/v) as mobile phase B. A Quality by Design (QbD) based Design of Experiments (DoEs) was employed to evaluate the robustness characteristics of the analytical method validation. RESULTS The obtained % RSD from the precision and intermediate precision was 0.4% to 4.1%. The % recovery of the impurities from LOQ to 150% of specification level was 87.5% to 110.3%. The linear regression curves for the impurities with a correlation coefficient of > 0.999 indicate that all peak responses are linear with the concentration. The sample and standard solutions were stable till 24 h at benchtop and refrigerator conditions. CONCLUSION All the critical peaks were well separated from the forced degradation studies' diluent, placebo, and generated degradation peaks. The method validation data and QbD based robustness study results indicate that the developed impurities method fits the routine quality control laboratory use. National environmental index (NMEI), Green analytical procedure index (GAPI), Analytical Eco-scale and Analytical greenness (AGREE) tools expressed the method greenness. HIGHLIGHTS The proposed method is QbD utilized and green chemistry assessed impurities determination method for OPT in nasal spray formulation.
Affinity Crosslinking and SDS-PAGE

Interleukin 1 (IL-1), l a polypeptide hormone produced by activated macrophages, has been reported to mediate an apparently diverse range of biological activities (1-3). These include lymphocyte-activating factor (LAF) (4), endogenous or leukocyte pyrogenic activity (5), epidermal cell thymocyte-activating factor (6), bone resorption factor (7, 8), and fibroblast growth factor (9). In general, this set of activities would seem to be consistent with the notion that ILl acts as a soluble mediator during inflammatory responses. We have recently purified to homogeneity a polypeptide secreted by human monocytes that produces several IL-l-like effects (10). The initial step in the action of IL-1 is most likely the binding of this hormone to plasma membrane receptors. The availability of purified IL-1 in our laboratory rendered a search for such receptors possible. For the initial characterization of the plasma membrane (IL-1) receptors, we chose the murine T lymphoma LBRM33-1A5 as a model cell. This cell line produces interleukin 2 in response to suboptimal doses of phytohemagglutinin (PHA) in an IL-l-dependent fashion, and constitutes a well-defined model system for IL-1 action (11, 12). Using radiolabeled human IL-1, we show that these cells bind IL-1 specifically and with high affinity. We further show that cell-bound IL-1 is associated with a membrane protein of -80,000 mol wt. Finally, we have surveyed a broad range of cell types from several species for 125I-IL-1 binding. In general, the data are consistent with the known biological effects of IL-1, in that cell types which bind IL-1 are those previously reported to respond to it. The cell types that showed significant levels of IL-1 binding were either lymphoid in origin or fibroblast/ epithelial type cells. The data support the view that, like other polypeptide hormones, IL-1 action is mediated by a specific plasma membrane receptor protein. The characterization of this protein, both at the functional and structural levels, should aid in understanding the diverse biological activities of IL-1.
SAUDI TELECOM INDUSTRY

The telecommunications sector in Saudi Arabia is continuously seeking to a close relationship with their customers. Most telecom companies have Customer Relationship Management (CRM) system. However, implementing CRM systems have a low success rate. This paper aims to propose a model that helps the telecom companies to increase the level of implementing successful CRM system. A model is drawn to identify the critical success factors that contribute to successful CRM system in Saudi telecommunication sector. Seven basic hypotheses were tested, as parts of a theoretical model of successful CRM system. Data was collected through a questionnaire. The empirical analysis was carried out using a structural equation model and regression. In addition, follow-up interviews were conducted with a small number of top managers. Data obtained from the questionnaire was triangulated with data gathered from follow-up interviews. The findings revealed that the seven hypotheses were supported and lead to CRM success.
EVALUATION OF DIFFERENT CURING ENERGIES ON SOME PROPERTIES OF TWO RECENT RESINS COMPOSITE

Objective: Evaluation the curing capability of laser energy on new types of dental composites, in comparison to what’s already available, is one of the main aims for this study, regarding the values of microhardness and the degree of conversion. Methods: Fifty-six specimen prepared from two types of dental resin composites (SDR BulkFil© and Ceram.X One© resin composite), twenty-eight from each type of composite divided for four subgroups seven specimen for each. Samples were prepared in a Teflon split mold with fixed dimensions packed in incremental technique following the manufactures instructions, to produces each specimen in cylindrical shape with 4mm diameters and 6mm thickness. Three of each subgroup cured with different curing time using (SIROLaser© Blue laser, Sirona) laser device for (5sec,10sec and 20sec) respectively on 445nm wavelength and 500 mw power, and the last group cured by (BlueLEX LD-105, Monitex©) LED curing unit for 20sec. The microhardness of top and bottom surfaces tested by Vicker’s hardness testing machine (HV-1000DT) and then the specimens powdered and tested for the degree of conversion using Fourier transform infrared spectroscopy (Agilent Cary 630 FTIR). Results: For SDR BulkFil composite resin group, top surface; It was found that 5-seconds laser cured subgroup recorded the highest mean ± SD value of Vickers μ-hardness by 20-seconds LED cured subgroup. Regardless to composite resin type, it was found that, laser curing energy recorded higher (DC) percentage mean values than LED curing one. Conclusions: SIROLaser Blue laser device (500 mw/ cm2 and wavelength 445nm) have a significant capability of curing of Dental composites. Inanition, regardless to curing energies, it was concluded that Ceram.X One resin composite recorded statistically significant higher (DC) percentage mean values than SDR BulkFil composite resin.
Perspectives of Thai Healthcare Providers and Nursing Students on the myPlan App for Abused Women

Intimate partner violence is common in Thailand. The myPlan app (www. myplanapp.org) is an individualized, evidence-based safety planning decision aid for abused women. The aim of this study was to explore the perspectives of Thai providers working with abused women regarding the potential usefulness and feasibility of app-based interventions in the Thai context. We conducted an exploratory qualitative study in a province in northeast Thailand. Using a semi-structured interview guide, we conducted Thai-language focus groups and interviews with a convenience sample of service providers, health providers, and nursing students. These lasted 90-120 minutes and were recorded, transcribed verbatim, and analyzed qualitatively. There were 67 participants (seven focus groups and one in-depth interview). Overall, participants described app-based interventions as likely being appropriate for Thai culture, aligned with Thai government policy and resources, and having potential to help abuse survivors. Internet access in rural areas was an area of concern, as was the readiness of health and social service providers to respond to survivors and the effectiveness of referral systems. In conclusion, participants view app-based safety planning as largely possible and feasible in the Thai context. Future research is needed to include survivors’ perspectives on myPlan app, as well as on culturally-specific, evidence-based risk assessment and safety planning for Thai survivors to inform and tailor of adapting the myPlan app. Mixed-methods and longitudinal research is needed for future research. Pacific Rim Int J Nurs Res 2020; 24(3) 389-402
Microwave Characterization of Dielectric Material at 2.45GHz

We describe a near field microwave microscopy method for characterization and rapid non-destructive imaging of dielectric materials samples at 2.45 GHz. This system is composed of a probe coupled to a dielectric resonator. It is used for two purposes: first to characterize dielectric samples with accuracy and high spatial resolution, knowing that they do not have predetermined forms but a small plane surface; and second, to draw dielectric cartographies for flat samples, with a 100 μm resolution.
A Semantic Web Multimedia Information Retrieval Engine

—We present a Semantic Web based approach that meets the requirements for multimedia information retrieval. For that, we developed a prototypical implementation using a Semantic Web framework, linking open data ontologies and image processing libraries. We show how the different mechanisms of the Semantic Web may help multimedia management, both for storage and in retrieval tasks.
RMHP_A_302309 1969..1984

1Family Medicine Department, Faculty of Medicine, King Abdulaziz University, Jeddah, Saudi Arabia; 2Ibn Sina National College for Medical Studies, Jeddah, Saudi Arabia; 3Faculty of Medicine, King Abdulaziz University, Jeddah, Saudi Arabia Background: To assess knowledge and attitudes about e-smoking among undergraduate medical students, specifically focused on favorable view of therapeutic e-cigarette use for smoking cessation or harm reduction. Methods: This cross-sectional study included medical students at King Abdulaziz University, Saudi Arabia. A six-item subscale was used to explore knowledge and attitudes about the therapeutic use of e-cigarettes, measuring participants’ likelihood of favoring such use. A four-item questionnaire measured confidence and importance of being educated about smoking and e-smoking, in addition to sources of knowledge about e-cigarettes. Results: A total of 399 students participated. Smoking history included current smokers (19.8%) and ex-smokers (6.5%), while e-cigarettes were tried by 36.6% and are currently used by 11.5%. A minority (13.5%) believed that e-cigarettes are FDA-approved for smoking cessation, while approximately one-third believed e-smoking lowers cancer risks (31.1%) and could help with smoking cessation (31.1%). Further, 35.9% agreed or strongly agreed that e-cigarettes are better for patients than tobacco products, and 17.5% were likely to recommend e-smoking to their patients for smoking cessation. Reliability of the six-item scale showed Cronbach’s alpha = 0.676, which was enhanced to 0.746 after deletion of one item about addictiveness. Using the corrected five-item scale, 23.6% of the participants would favor therapeutic use of e-cigarettes. Conclusion: We observed several misconceptions about addictiveness and inadequate awareness about e-cigarettes’ harmful effects, leading to non-scientific opinions about its therapeutic use for harm reduction or in smoking cessation. Academic programs around this topic should be updated in accordance with majority expert recommendations.
Variable Complexity Neural Networks Comparison for Pollen Classiﬁcation

—This paper deals with the problem of classifying the pollen grains observed in a microscope view acquired by a collector of ambient air particles. This classiﬁcation is usually performed by a highly skilled human operator observing the microscope slide to detect the presence of pollen grains, count them and sort them according to their taxa. However these tasks become particularly heavy in the mid-season because of the huge quantity of pollen produced. This paper compares the use of three neural networks (NN) to classify the pollen grains observed which are a modiﬁed version of LeNet5, ResNet50 and AlexNet. The ﬁrst two have been conceived more for non-natural images and the last one for natural images. Simulation shows that ResNet50 and AlexNet particularly lead to good performance in terms of accuracy for this kind of images. AlexNet is ﬁnally a good compromise for pollen classiﬁcation when adding a constraint on the computational complexity.
STRATEGIZING EM CONTEXTO PLURALISTAS: UMA REVISÃO NARRATIVA DA LITERATURA STRATEGIZING IN PLURALISTIC CONTEXTS: A NARRATIVE LITERATURE REVIEW

Objective: Considering that pluralism has been relatively ignored by classical studies on strategy, and that it is increasingly present in 21st century organizations (Jarzabkowski & Fenton, 2006), the goal of this study was to understand how knowledge of strategizing in pluralistic contexts has been broadened on the basis of the research conducted by Jarzabkowski and Fenton (2006). Methods: We adopted a qualitative approach to make a narrative literature review, searching on the Ebsco, Scopus and Periódicos Capes databases. Six publications on strategizing in pluralistic contexts were selected and grouped according to their common characteristics: tensions in strategic management in pluralistic contexts; empirical studies on strategies in pluralistic contexts; and proposals on how to deal with the pluralism of organizations. Originality/relevance: This research emphasized the importance and the need to advance the knowledge of strategies in pluralistic contexts, considering the plurality that is commonly found in contemporary organizations. Results: Our results indicate that strategizing in pluralistic contexts is a recent topic which has been little addressed by the strategy research agenda. The six selected studies point out to tensions inherent in pluralist contexts: some address how certain environments deal with these pressures while others propose solutions to minimize the pluralism of organizations. Theoretical/methodological contributions: Our study contributed to the compilation and analysis of the advancement of knowledge about strategizing in pluralistic contexts. We identified the rise of this field of research and stressed the need to develop this theme in view of the progress of the plurality that is present in organizations.
PII: S1010-7940(99)00309-7

Objective: To assess midterm results after aortic valve replacement (AVR) with an autologous tissue cardiac valve (ATCV). This new technique was developed to construct a tissue prosthesis for AVR using the patients pericardium, harvested at the time of operation with negligible effect on operating time. Methods: Brie ̄y, glutaraldehyde tanned pericardium is mounted on a stent requiring no suturing. Between March 1994 and December 1996, 87 patients, 44/43 M/F and aged 70 ^ 6 years had AVR for aortic stenosis (80%), aortic insuf®ciency (6%) and combined lesions (14%), one patient suffered from endocarditis. Additional coronary artery bypass was done in 25%, aortic root enlargement in 7%. Aortic cross clamp and cardiopulmonary bypass times were 69 ^ 21 and 93 ^ 29 min. All patients were followed by clinical examination and color ̄ow Doppler echocardiography in 3±12 months interval. Follow up was 99% complete. Results: There were ®ve perioperative deaths (6%), none of them valve related. Eighty-one patients were followed up to a period of 52 months (mean interval 37:5 ^ 1:3 months), one patient was lost for follow up. Overall survival was 86, 81, 79 and 71% at 12, 24, 36 and 48 months, respectively. There were 14 late deaths with eight (10%) valve related (four cerebral deaths, four sudden deaths). Sixteen patients (20%) had to be re-operated due to severe valve incompetence. Freedom from reoperation was 98, 97, 90 and 63% at 12, 24, 36, and 48 months, respectively. Valve incompetence occurred suddenly, without previous signs in the follow-up examinations. Selection and preparation of the pericardium, the way of ®xation of the tissue ± brief immersion in glutaraldehyde ± and engineering problems might be responsible for this disastrous outcome. Conclusion: Due to these results we must state, that the ATCV did not ful®ll our expectations and presently we can not recommend it as an aortic valve substitute. q 1999 Elsevier Science B.V. All rights reserved.
Analysis ofMalassezia microbiota in healthysuper¢cial humanskin and in psoriatic lesionsbymultiplex real-timePCR

Analysis ofMalassezia microbiota in healthysuper¢cial humanskin and in psoriatic lesionsbymultiplex real-timePCR Luciana C. Paulino, Chi-Hong Tseng & Martin J. Blaser Department of Medicine, New York University School of Medicine, NY, USA; Department of Microbiology, New York University School of Medicine, NY, USA; and Department of Environmental Medicine, New York University School of Medicine, NY, USA
Scientific Opinion on the influence of genetic parameters on the welfare and the resistance to stress of commercial broilers

This scientific opinion describes the influence of genetic parameters that have affected the welfare of commercial broilers. There is a lack of robust scientific data for Europe on welfare outcome indicators and these should be recorded independently and made publicly available. The major welfare concerns that have a genetic basis and that may interact with management factors to lead to poor welfare include skeletal disorders, contact dermatitis, ascites and sudden death syndrome. Most of these are linked with fast growth rates. There are also numerous interactions between the environment and the genetic traits that can seriously adversely affect welfare in areas such as lighting regimes, litter management, dietary deficiencies and contamination, air quality and temperature. In the risk assessment the probability of exposure to a hazard, and the magnitude of the poor welfare effects (consequences) of that exposure were estimated. The major risk scores were unbalanced body conformation, high stocking density, fast growth rate, low light intensity and wet litter. The top ranking environmental hazards were high stocking density, low light intensity and wet litter. It was recognised by the experts that probabilities vary from region to region, country to country and among different types of farming system. Recommendations include better data collection in Europe, greater selection strategies for improved welfare traits with birds being selected and tested for their subsequent rearing and production environments by the breeders. Finally, a high priority should be given to decreasing the proportion of birds with the higher gait scores, and to include contact dermatitis and other welfare traits in the selection schemes.