Miracle-dz/UniFAR-FTUs huggingface dataset:
Computer aided design for dual‐band filters with complex source and load impedances

This article presents a computer aided technique to synthesize the filtering function for dual‐band microwave filters with complex source and load impedances. Based on the exchange‐Remez algorithm and the power wave renormalization theory, the characteristic function is first obtained with assigned ripple level at the first passband. Two additional transmission zeros are then optimally allocated to control the ripple level at the second passband. By directly modifying the coupling matrix elements in the first and last stages, a simplified method is also presented when the loading impedance is frequency‐independent. Three synthesized examples with both controlled in‐band and out‐of‐band responses are presented. Finally, LC multi‐coupled circuits are also provided to validate the effectiveness of the proposed method.
Efficient Place and Routing CAD Techniques for the Reduction of Power Dissipation in FPGAs

: The Computer Aided tools (CAD) are used to transform the design into a stream of ‘1’s and ‘0’s. This stream of bits is used to program the FPGA during the configuration time. Generally a huge number of programmable switches are used to implement FPGA. These switches are mainly used to implement functional blocks in FPGA. The CAD tools of FPGAs convert the design entered either using hardware description language or as schematic to a binary bit stream of ‘0’s and ‘1’s. During the configuration time, this bit stream effectively program the FPGA. On the CAD level, the packing and placement stages are modified to allow the possibility of dynamically turning OFF the idle parts of the FPGA to reduce the leakage power and as well as to reduce total power dissipation. A new activity generation algorithm is proposed and implemented that aims to identify the logic blocks in a design that exhibit similar idleness periods. Several criteria for the activity generation algorithm are used, including connectivity and logic function. Several versions of the activity generation algorithm are implemented to trade power savings with runtime. A newly developed placement and packing algorithm uses the resulting activities to minimize leakage power dissipation by packing the logic blocks with similar or close activities together. In this paper, the proposed architecture of FPGA using MTCMOS and the corresponding CAD tools save the average power of 30% in 90mm CMOS technology with less performance penalty.
Improved transient silencing of gene expression in the mosquito female <fc><fi>Aedes aegypti</fi></fc>

Gene silencing using RNA interference (RNAi) has become a widely used genetic technique to study gene function in many organisms. In insects, this technique is often applied through the delivery of dsRNA. In the adult female Aedes aegypti, a main vector of humaninfecting arboviruses, efficiency of gene silencing following dsRNA injection varies greatly according to targeted genes. Difficult knockdowns using dsRNA can thus hamper gene function analysis. Here, by analysing silencing of three different genes in female Ae. aegypti (p400, ago2 and E75), we show that gene silencing can indeed be dsRNA sequence dependent but different efficiencies do not correlate with dsRNA length. Our findings suggest that silencing is likely also gene dependent, probably due to gene-specific tissue expression and/or feedback mechanisms. We demonstrate that use of high doses of dsRNA can improve knockdown efficiency, and injection of a transfection reagent along with dsRNA reduces the variability in efficiency between replicates. Finally, we show that gene silencing cannot be achieved using siRNA injection in Ae. aegypti adult females. Overall, this work should help future gene function analyses using RNAi in adult females Ae. aegypti, leading toward a better understanding of physiological and infectious processes.
Learning to Play Breakout Using Deep Q-Learning Networks

—We cover in this report the implementation of a reinforcement learning (RL) algorithm capable of learning how to play the game Breakout on the Atari Learning Environment (ALE). The non-human player (agent) is given no prior information of the game and must learn from the same sensory input that a human would typically receive when playing the game. The aim is to reproduce previous results by optimizing the agent driven control of Breakout so as to surpass a typical human score. To this end, the problem is formalized by modeling it as a Markov Decision Process. We apply the celebrated Deep Q-Learning algorithm with action masking to achieve an optimal strategy. Weﬁnd our agent’s average score to be just below the human benchmarks: achieving an average score of 20, approximately 65% of the human counterpart. We discuss a number of implementations that boosted agent performance, as well as further techniques that could lead to improvements in the future.
OARRR_A_228083 309..321

1Department of Paediatric and Adolescent Rheumatology, Royal Manchester Children’s Hospital, Manchester University Hospitals NHS Trust, Manchester M13 9WL, UK; 2Versus Arthritis Centre for Epidemiology; Centre for MSK Research, University of Manchester, Manchester, UK; 3NIHR Biomedical Research Centre, Manchester University Hospital NHS Trust, Manchester, UK Abstract: Consideration of the mental health and emotional wellbeing is an important component of health care for all young people, irrespective of setting. Mental health disorders are common during adolescence and young adulthood and young people with rheumatic musculoskeletal diseases (RMD) are not exempt. For such young people, risks of poor outcomes are related to both mental health as well as their RMD. Times of change during adolescence and young adulthood—transitions—are potentially vulnerable life stages for young people with RMD and warrant specific attention in health care provision. Such transitions include those occurring at puberty, during education, training, and employment, socially with moves away from the parental home, as well as from child to adult-centered health services. There is great potential for rheumatology professionals to support young people with RMD at these transitions in view of their frequent encounters and ongoing therapeutic relationships. In this review, we aim to assess the impact of mental health on RMD during adolescence and young adulthood with particular reference to transitional care provision and how rheumatology professionals can be involved in addressing mental health issues during this time of change.
Characterization of cultivated varieties of Capsicum pubescens in Michoacán, Mexico

The state of Michoacán has diverse homogeneous agro-ecological zones that favor the wide diversity of plant species, which includes the cultivation of chili, considered one of the main crops worldwide. The cultivation of C. pubescens has gained greater importance in recent years due to the increase in its production. This species has broad genetic variability that can be used in breeding programs. However, the variability in the state of Michoacán has not been sufficiently documented, so the genetic potential it represents is unknown. In the present work, the collection and morphological characterization of cultivated varieties of C. pubescens in different agroecological zones was proposed in order to evaluate the morphological variability and relate it to the different existing agro-ecological conditions. The in situ morphological characterization was made based on the descriptors proposed by IPGRI, AVRDC and CATIE and UPOV, the evaluation included 27 characteristics of leaf, fruit and seed. The results obtained indicate that there is a wide variability in the cultivated varieties of C. pubescens. Likewise, the fruit characteristics were identified as the most important to discriminate the varieties with potential to be used, as quality parameters, in breeding programs. Finally, no relationship was found between the morphological variability of C. pubescens and the sites of origin of the cultivated varieties.
CLEP_A_199839 275..283

Lotte Sahin Levison Reimar Wernich Thomsen Diana Hedevang Christensen Thomas Mellemkjær Søren Hein Sindrup Henning Andersen 1Department of Neurology, Aarhus University Hospital, Aarhus, Denmark; 2Department of Clinical Epidemiology, Aarhus University Hospital, Aarhus, Denmark; 3Department of Neurology, Odense University Hospital, Odense, Denmark Purpose: To validate the diagnostic codes for Guillain-Barré syndrome (GBS) in the Danish National Patient Registry (DNPR). Secondly, to examine 30-year trends in the incidence of GBS in Denmark. Patients and methods: We used the DNPR to identify all patients aged 16 and above diagnosed with a primary GBS diagnosis at any Danish department of neurology between 1987 and 2016. Medical files were reviewed according to the clinical criteria of the National Institute of Neurological Disorders and Stroke Committee and classified according to the Brighton criteria. The incidence rate (IR) was calculated based on data from 1987 to 2016 and stratified by season, gender, and age. Results: Over 30 years, we identified 2,319 patients aged 16 and above in the DNPR. From a validation cohort of 573 patients, we were able to retrieve 425 (74.2%) medical files; 356 GBS diagnoses were confirmed. The overall positive predictive value was 83.8% (95% confidence interval (CI): 80.0–87.0). In 99% of the confirmed patients, the Brighton criteria level 1–3 for GBS were met. The IR was fairly stable over 30 years at 1.77 per 100,000 person years (95% CI: 1.70–1.84). The incidence was higher in the winter season (IR ratio compared with summer: 1.18 (95% CI: 1.09–1.29)), and was strongly associated with male gender (IR ratio vs females: 1.44 (95% CI: 1.33–1.57)). IRs rose with age at diagnosis, particularly after the age of 50 in both men and women and a minor peak was observed for total IR in young adults. Conclusion: Primary diagnostic codes for GBS at Danish departments of neurology have high validity. The DNPR is a well-suited data source for epidemiological research on GBS. The Danish nationwide 30-year GBS IR is stable over time and similar to GBS IRs reported in other European and North American populations.
RH: MULTILOCUS DELIMITATION USING ROOTED TRIPLETS 2

21 Multilocus sequence data provide far greater power to resolve species limits than the single 22 locus data typically used for broad surveys of clades. However, current statistical methods 23 based on a multispecies coalescent framework are computationally demanding, because of the 24 number of possible delimitations that must be compared and time-consuming likelihood 25 calculations. New methods are therefore needed to open up the power of multilocus 26 approaches to larger systematic surveys. Here, we present a rapid and scalable method that 27 introduces two new innovations. First, the method reduces the complexity of likelihood 28 calculations by decomposing the tree into rooted triplets. The distribution of topologies for a 29 triplet across multiple loci has a uniform trinomial distribution when the 3 individuals belong 30 to the same species, but a skewed distribution if they belong to separate species with a form 31 that is specified by the multispecies coalescent. A Bayesian model comparison framework 32 was developed and the best delimitation found by comparing the product of posterior 33 probabilities of all triplets. The second innovation is a new dynamic programming algorithm 34 for finding the optimum delimitation from all those compatible with a guide tree by 35 successively analyzing subtrees defined by each node. This algorithm removes the need for 36 heuristic searches used by current methods, and guarantees that the best solution is found and 37 potentially could be used in other systematic applications. We assessed the performance of the 38 method with simulated, published and newly generated data. Analyses of simulated data 39 demonstrate that the combined method has favourable statistical properties and scalability 40 with increasing sample sizes. Analyses of empirical data from both eukaryotes and 41 prokaryotes demonstrate its potential for delimiting species in real cases.
MODELING OF PROCESSES IN TRANSPORT SYSTEMS BY FRACTAL METHODS

In the paper is proposed a model for studying of processes in a transport system by fractal methods. In view of the NDS general properties and examined categories: order, chaos and self-organization, the study is based on the synergistic approach to developing systems. On the basis of this has been performed research in the environment Matchcad with different values of system’s parameters.
COPD_A_270762 2653..2662

1State Key Laboratory of Respiratory Disease, Guangzhou Chest Hospital, Guangzhou, Guangdong, People’s Republic of China; 2State Key Laboratory of Respiratory Disease, Guangzhou Medical University, Guangzhou, Guangdong, People’s Republic of China; 3GMU-GIBH Joint School of Life Sciences, Guangzhou Medical University, Guangzhou, Guangdong, People’s Republic of China; 4The Research Center of Experiment Medicine, Guangzhou Medical University, Guangzhou, Guangdong, People’s Republic of China; 5State Key Laboratory of Respiratory Diseases, National Clinical Research Center for Respiratory Diseases, Guangzhou Institute of Respiratory Health, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, Guangdong, People’s Republic of China Background and Purpose: Recently, fine particulate matter (PM2.5) was identified as the main exposure risk for COPD, and inflammation is central to the development of COPD. In this study, we investigated whether PM2.5 can induce the secretion of interleukin-6 (IL-6), IL-8 and IL-1β in human bronchial epithelial cells (HBECs) in vitro via the wingless-related integration site 5A (Wnt5a)/receptor tyrosine kinase-like orphan receptor 2 (Ror2) signaling. Methods: The expression of Wnt5a and Ror2 was assessed by immunohistochemistry in motor vehicle exhaust (MVE)-induced Sprague-Dawley rats. HBECs were transfected with small interfering RNA (siRNA) targeting Wnt5a or Ror2 and subsequently stimulated with PM2.5. The secretion of IL-6, IL-8 and IL-1β was assessed by ELISAs, and the expression of Wnt5a/Ror2 signaling were assessed by RT-PCR and Western blotting. Results: Both Wnt5a and Ror2 protein were increased in the lung of MVE-induced rats. HBECs exposed to PM2.5 for 24 h significantly upregulated Wnt5a and Ror2 expression and subsequently promoted the nuclear translocation of NF-κB, which increased the production of IL-1β, IL-6 and IL-8. Wnt5a siRNA prevented these outcomes. Wnt5a antagonist (BOX5) also prevented inflammatory effects. Furthermore, Ror2 siRNA blocked the NF-κB activity and inhibited the release of IL-6, IL-8 and IL-1β from PM2.5-exposed HBECs. Conclusion: PM2.5 induces the secretion of IL-6, IL-8 and IL-1β in HBECs via the Wnt5a/ Ror2 signaling, demonstrating a novel mechanism for PM2.5-associated airway inflammation.
Cloning, Nucleotide Sequence, and Enzymatic Characterization of an cx-Amylase from the Ruminal Bacterium

A Butyrivibrio fibrisolvens amylase gene was cloned and expressed by using its own promoter on the recombinant plasmid pBAMY100 in Escherichia coli. The amylase gene consisted of an open reading frame of 2,931 bp encoding a protein of 976 amino acids with a calculated Mr of 106,964. In E. coli(pBAMY100), more than 86% of the active amylase was located in the periplasm, and TnphoA fusion experiments showed that the enzyme had a functional signal peptide. The B. fibrisolvens amylase is a calcium metalloenzyme, and three conserved putative calcium-binding residues were identified. The amylase showed high sequence homology with other a-amylases in the three highly conserved regions which constitute the active centers. These and other conserved regions were located in the N-terminal half, and no similarity with any other amylase was detected in the remainder of the protein. Deletion of approximately 40% of the C-terminal portion of the amylase did not result in loss of amylolytic activity. The B. fibrisolvens amylase was identified as an endo-oa-amylase by hydrolysis of the Phadebas amylase substrate, hydrolysis of y-cyclodextrin to maltotriose, maltose, and glucose and the characteristic shape of the blue value and reducing sugar curves. Maltotriose was the major initial hydrolysis product from starch, although extended incubation resulted in its hydrolysis to maltose and glucose.
Conservation and Divergence of Circadian Clock Operation in a Stress-Inducible Crassulacean Acid Metabolism Species Reveals Clock Compensation against Stress 1

One of the best-characterized physiological rhythms in plants is the circadian rhythm of CO 2 metabolism in Crassulacean acid metabolism (CAM) plants, which is the focus here. The central components of the plant circadian clock have been studied in detail only in Arabidopsis ( Arabidopsis thaliana ). Full-length cDNAs have been obtained encoding orthologs of CIRCADIAN CLOCK-ASSOCIATED1 ( CCA1 ) /LATE ELONGATED HYPOCOTYL ( LHY ), TIMING OF CAB EXPRESSION1 ( TOC1 ), EARLY FLOWERING4 ( ELF4 ), ZEITLUPE ( ZTL ), FLAVIN-BINDING KELCH REPEAT F-BOX1 ( FKF1 ), EARLY FLOWERING3 ( ELF3 ), and a partial cDNA encoding GIGANTEA in the model stress-inducible CAM plant, Mesembryanthemum crystallinum (Common Ice Plant). TOC1 and LHY/CCA1 are under reciprocal circadian control in a manner similar to their regulation in Arabidopsis. ELF4 , FKF1 , ZTL, GIGANTEA , and ELF3 are under circadian control in C 3 and CAM leaves. ELF4 transcripts peak in the evening and are unaffected by CAM induction. FKF1 shows an abrupt transcript peak 3 h before subjective dusk. ELF3 transcripts appear in the evening, consistent with their role in gating light input to the circadian clock. Intriguingly, ZTL transcripts do not oscillate in Arabidopsis, but do in M. crystallinum . The transcript abundance of the clock-associated genes in M. crystallinum is largely unaffected by development and salt stress, revealing compensation of the central circadian clock against development and abiotic stress in addition to the well-known temperature compensation. Importantly, the clock in M. crystallinum is very similar to that in Arabidopsis, indicating that such a clock could control CAM without requiring additional components of the central oscillator or a novel CAM oscillator.
Misperception of Italian Singleton and Geminate Obstruents by Native Japanese Speakers

Misperception of voiced and voiceless obstruent length in Italian by native Italian and native Japanese speakers was compared. Both Italian and Japanese use consonant length contrastively. This may lead to the expectation that there is a positive first language transfer for the native Japanese speakers. While the native Japanese listeners’ misperception of Italian length categories was limited, they still made significantly more errors than the native Italian listeners. The native Japanese listeners’ length misperception was more noticeable when the word-medial obstruent was short than when it was long and when it was voiced than when it was voiceless.
ISSN 2320-5407 International Journal of Advanced Research (2016), Volume 4, Issue 4, 241-253

A. M. M. Liela. Potato (solanum tuberosum, L.) is one of the most important vegetable crops in Egypt, it is considered as a source of national income since the potato crop is exported abroad because it has high quality specification. As a result of its cheap price and different prepared ways, potato is the most consuming crop by domestic consumer. So, the need to maintain the potato quality and preserve the crop without losses, providing good storage conditions after harvest is an important process for inhibiting sprouting, reduce the loss of weight and keeping the quality. The aim of this study is to investigate the effect of different doses of ultraviolet light (0, 1.42, 2.14 and 2.85 J/cm 2 ) and different storage conditions (ambient air 45 ± 2 o C with 50-60% RH, two cold dark storages, at 8 o C±1with 75-82% RH and13 o C±1 with 85-92% RH) on inhibition the sprouting of small tubers (60-90g) and big tubers (120-220g) after four months of storage. The analysis of variance(ANOVA) with three replicates (P < 0.05) based on Randomized Complete Block Design(RCBD) was conducted for the statistical analysis. It was concluded that increasing irradiation doses and decreasing storage temperature is good combination for sprouting suppression, reducing weight loss percentage, reducing the increment of soluble solids content, increasing firmness and remaining on the dry matter content almost constant. Only the tubers of non-irradiated treatment under ambient air storage showed percentage of damage. While,10 min irradiation treatment was very low to be effective in sprouting suppression or maintain other quality attributes at all storage temperatures. Exposure of 15 min UV-C is recommended as post-harvest treatment when small tubers are stored at 8 o C. Storing tubers at 13 o C after high irradiation doses showed very low sprouting weight for small and big tubers.
Horizon 2020 Program Security and resilience for collaborative manufacturing environments ICT-2019-2 A COmprehensive cyber-intelligence framework for resilient coLLABorative manufacturing Systems D1.1: COLLABS Innovations for Industrial IoT Systems

In this deliverable we briefly summarize significant new research results and new commercial products that have been published or released on the market, since the submission of the project proposal in 28/03/2019, in the technological areas where COLLABS aims to advance the state-of-the-art (SotA thereafter). The goal of this document is to ensure that the starting point for these targeted advances is up to date. It thus contains one section for each technological area listed as a target for advancement in Section 1.4. 1. of the proposal which describes the project’s offerings beyond the SotA. 1 The research leading to these results has received funding from the European Union’s Horizon 2020 research and innovation programme under grant agreement No 871518. Ref. Ares(2020)2300074 30/04/2020 COLLABS D1.1 ICT-2019-2/No 871518 COLLABS 2 April 30, 2020 Contractual Date of Delivery 30/04/2020 Actual Date of Delivery 30/04/2020 Deliverable Security Class Public Editor Miloš Radovanović, UNSPMF Contributors Wafa Ben Jaballah, TSG George Bravos, ITML Andreas Brokalakis, FORTH Erwan Le-Disez, REN Ernesto Gomez Marin, IFAG Erwin Moed, PCL Md Masoom Rabbani, UNIPD Miloš Radovanović, UNSPMF Valerio Senni, Fabio Federici, ALES George Spanoudakis, Konstantinos Fysarakis, STS Quality Assurance Prabhakaran Kasinathan, Martin Wimmer, SAG Panagiotis Rizomiliotis, HUA The COLLABS Consortium 1 COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES CEA France 1 36 2 IDRYMA TECHNOLOGIAS KAI EREVNAS FORTH Greece 1 36 3 PHILIPS CONSUMER LIFESTYLE BV PCL Netherlands 1 36 4 INFINEON TECHNOLOGIES AG IFAG Germany 1 36 5 ADVANCED LABORATORY ON EMBEDDED SYSTEMS SRL ALES Italy 1 36 6 UNIVERSITY OF NOVI SAD FACULTY OF SCIENCES UNSPMF Serbia 1 36 7 SPHYNX TECHNOLOGY SOLUTIONS AG STS Switzerland 1 36 8 THALES SIX GTS FRANCE SAS TSG France 1 36 9 INFORMATION TECHNOLOGY FOR MARKET LEADERSHIP ITML Greece 1 36 10 UNIVERSITA DEGLI STUDI DI PADOVA UNIPD Italy 1 36 11 SIEMENS AKTIENGESELLSCHAFT SAG Germany 1 36 12 RENAULT SAS REN France 1 36 13 HAROKOPIO UNIVERSITY HUA Greece 1 36 COLLABS D1.1 ICT-2019-2/No 871518 COLLABS 3 April 30, 2020 Document Revisions & Quality Assurance