Miracle-dz/UniFAR-FTUs huggingface dataset:
Identifying alien bryophytes taking into account uncertainties: a reply to Patiño & Vanderpoorten (2015)

Recently, Patiño & Vanderpoorten (2015, Journal of Biogeography, 42, doi:10.1111/jbi.12492) commented on our manuscripts about patterns and processes of global bryophyte invasions. In particular, they argued that the criteria we have used to identify alien bryophytes (i.e. anomalous geographical distribution, preference for disturbed habitats, indirect associations with some means of human transport) are insufficient in the absence of further evidence. We fully agree with this statement. Consequently, we had used the above‐mentioned criteria only for the identification of ‘cryptogenic’ (i.e. probable alien) species and have stated this explicitly in our manuscripts. Thus, we conclude that Patiño & Vanderpoorten (2015) have drawn misleading conclusions on the way we defined aliens. Nevertheless, we acknowledge that given the excellent long‐distance dispersal capacities of bryophytes, diverging opinions between different experts on the native, alien or cryptogenic status of a particular bryophyte species in a given region do sometimes exist.
High intensity gap light coupling of nano-antenna to high Purcell factor photonic crystal nano cavity

An efficient hybrid photonic-plasmonic structure which combines the resonant mode of an ultrahigh Purcell factor photonic crystal nano-cavity with plasmonic resonance of a bowtie nano-antenna with a high accuracy has been presented in this article. The consequential enormous light intensity enhancement of ~3×106 times in the gap region of the bowtie nanoantenna (in the coupled structure with respect to the incoming exciting light), originated from the effective optical resonance combination, is realized by subtle optimization of nano-cavity’s geometrical parameters. The designed coupled structure holds great promise for many applications and purposes trusting on strong confinement and e…
Strategic optimisation of short- and long-term gain and inbreeding in MAS and non-MAS schemes.

BACKGROUND The first question that should be addressed is: why distinguish the optimisation of shortand long-term gain (∆G) in a breeding scheme ? Why should a scheme that is optimal for shortterm gain become sub-optimal for long-term gain ? The answer is that the risks attached to achieving the objective of the breeding scheme will change with the perspective. Ignoring such risks in practical livestock breeding (where even the long-term is, say, ten generations) will tend towards solutions that argue for selecting the fewest possible males and females for breeding that reproductive biology will allow. Nevertheless there are clear risks in genetic selection that can be identified, even in the short-term. It is the procedures to manage these risks that provide the framework for much of the strategic optimisation to be described in this paper.
Isolation and Characterization of a Small Cryptic Plasmid from a Clinical Isolate of Burkholderia pseudomallei (การแยกและการศึกษาคุณลักษณะของ พลาสมิดขนาดเล็กจากเชื้อ Burkholderia pseudomallei ที่แยกได้จากผู้ป่วย)

โรคเมลออยโดสสเปนโรคตดเชอแบคทเรยทมสาเหตมาจากเชอ Burkholderia pseudomallei ซงสามารถกอโรคทมความรนแรงถงแกชวตไดในมนษย โรคนพบไดสวนใหญในแถบเอเชยตะวนออกเฉยงใต และทางตอนเหนอของประเทศออสเตรเลย ปจจบนยงไมพบการศกษาถงพลาสมดของเชอ B. pseudomallei ในเชงลก การศกษาเบองตนพบวาวธ alkaline lysis ซงเปนวธมาตรฐานไมสามารถจะใชในการสกดพลาสมด จากเชอ B. pseudomallei ได เวนแตไดรบการปรบปรงโดยการเพมความเขมขนของ sodium dodecyl sulfate เปน 7 เปอรเซนต เมอนำวธสกดพลาสมดทปรบปรงใหมนไปใชในการตรวจหาพลาสมดจากเชอ B. pseudomallei จำนวน 1,054 ตวอยาง ทแยกไดจากผปวยจากโรงพยาบาลประจำจงหวด 17 แหง ในภาคตะวนออกเฉยงเหนอของประเทศไทย พบเชอทมพลาสมดขนาดเลกจำนวน 23 ตวอยาง คดเปน 2.2 เปอรเซนต โดยสามารถแบงกลมพลาสมดทพบออกไดเปน 2 กลม ตามขนาดของพลาสมดและรปแบบการยอยดวยเอนไซมตดจำเพาะ จากการศกษาคณลกษณะโดยการตรวจหาลำดบเบสของพลาสมด pPHB194 พบวามขนาด 13,482 คเบส โดยม G + C ทงหมด 61 เปอรเซนต พบเปนพลาสมดทยงไมมรายงานในฐานขอมล โดยประกอบดวย 15 putative open reading frames (OFR) ซงบรเวณทมหนาทเกยวของกบการแบงตวของพลาสมดคอ ORF-10 เกยวของกบความเสถยรคอ ORF-8 และ ORF-9 และสวนทเกยวของกบการสงผานพลาสมดคอ ORF-11, ORF-12 และ ORF-14 โดยพบวาพลาสมด pPHB194 มจำนวนพลาสมด 11 copies ตอหนงโครโมโซมของเซลลแบคทเรย ขอมลดงกลาวมประโยชนในการนำไปใชในการผลต shuttle vector
Cairo - the divided city : policy versus reality and the journey to sustainability

3 CHAPTER 1: INTRODUCTION . 16 1.1. Background and theoretical framework . 20 1.1.1. The rapid rate of urbanisation and its impact . 20 1.1.2. Urbanisation and housing issues . 22 1.1.3. Housing between policy and informality . 23 1.2. Research objectives . 25 1.3. Research questions . 28 1.4. Analytical framework . 29 1.5. Thesis structure . 32 CHAPTER 2: THE MEANING OF SHELTER . 35 2.
Didáctica como conducta: : Una propuesta para la descripción de las habilidades de enseñanza

En el presente trabajo se describe el Modelo Interconductual de Desempeno Didactico (MIDD) en concordancia con una descripcion de desarrollo psicologico. El MIDD propone que el ejercicio que tiene quien ensena en la interaccion didactica puede ser ubicado en siete ambitos de desempeno en los cuales se desarrollan habilidades y competencias especificas: 1) La planeacion didactica, 2) la exploracion competencial, 3) la Explicitacion de criterios, 4) la ilustracion, 5) la supervision de la practica, 6) la retroalimentacion, y 7) la evaluacion. Cada uno de estos ambitos es descrito en terminos de habilidades conductuales: de acuerdo al tipo de desempeno que implican, el proposito que se persigue tal desempeno y la situacion en que ese desempeno es funcional. Finalmente, se describen los resultados generales de algunos estudios derivados del MIDD asi como sus implicaciones para investigaciones futuras y potenciales aplicaciones.
The role of voltage-gated sodium channels in non-small cell lung cancer

Various ion channels are expressed in human cancers where they are intimately involved in proliferation, angiogenesis, migration and invasion. Expression of functional voltage-gated sodium (Nav) channels is implicated in the metastatic potential of breast, prostate, colon, cervical and lung cancer cells. However, the cellular mechanisms that regulate Nav channel expression in cancer remain largely unknown. Growth factors are attractive candidates; they not only play crucial roles in cancer progression but are also key regulators of ion channel expression and activity in non-cancerous cells. Here, the role of epidermal growth factor receptor (EGFR) signalling and Nav channels in non-small cell lung cancer (NSCLC) cell lines have been examined. It is shown that functional expression of Nav1.7 promotes invasion in strongly metastatic H460 NSCLC cells. However, in non-invasive A549 NSCLC cells, Nav1.7 is completely absent. Inhibition of Nav1.7 either pharmacologically by tetrodotoxin (TTX) or genetically by small interfering RNA (siRNA) reduces H460 cell invasion by up to 50%. Whilst EGFR signalling enhances proliferation, migration and invasion of H460 cells, EGFR-mediated upregulation of Nav1.7 specifically, is required to promote invasive behaviour in these cells. Examination of Nav1.7 expression at the mRNA, protein and functional levels further reveals that EGFR signalling via the ERK1/2 pathway controls transcriptional regulation of Nav1.7 expression to promote cellular invasion in NSCLC. The role of Nav channels in promoting cancer cell invasion is also unclear. Therefore, the effect of Nav channel activity on two likely downstream contributors to cellular invasion, intracellular calcium concentration, [Ca2+]i, and intracellular pH, pHi, have been examined. It is shown that functional expression of Nav1.7 likely drives H460 NSCLC cell invasion via H+ efflux from the cell in an uncharacterised mechanism potentially involving NHE1, resulting in extracellular acidification of the perimembrane space. However, much more work is needed to understand this Na+-dependent invasive mechanism. Immunohistochemistry (IHC) of patient biopsies confirms the clinical relevance of Nav1.7 expression in NSCLC. Thus, Nav1.7 has significant potential as a novel target for therapeutic intervention, possibly in conjunction with existing EGFR inhibitors, and/or as a diagnostic/prognostic marker in NSCLC.
Control of Zabrotes subfasciatus (Boheman) (Coleoptera, Chrysomelidae, Bruchinae) in Phaseolus vulgaris Linnaeus, using diatomaceous earth under different temperatures.

Diatomaceous earth (DE) is a nontoxic and efficient method to control many insect pests of stored grains, but there is no information about the viability of its use for controlling the Mexican bean weevil Zabrotes subfasciatus (Boheman, 1833) (Coleoptera, Chrysomelidae, Bruchinae). Laboratory assays were conducted under different temperature and DE dosage combinations in order to determine the effect of such interactions to control this pest species. Bean samples were treated with 0.0; 0.50; 0.75 and 1.00 g of DE/kg of grain. Couples of Z. subfasciatus were placed in the vials of each treatment and kept in rearing chambers at 15, 20, 27 and 30 C, 70 ± 10 % r.h. , and 24 h scotophase. Diatomaceous earth at any dosage tested caused significant Z. subfasciatus mortality, especially in temperature of 27 and 30 C. After five days of exposure, death rates of Z. subfasciatus were about 100 % for all DE dosages and in temperature above 20 C. However, at 27 C the insects reproduced and laid a large number of eggs before dying. The use of 0.75 and 1.00 g of DE/kg dosages is recommended based on the tests. The interaction of DE and temperature leads to almost 100 % of mortality on the fifth day of exposure. It was concluded that Z. subfasciatus is very susceptible to DE treated beans.
Excitatory amino acids : their role in neuroendocrine function

Glutamate Neurotransmission in the Neuroendocrine Hypothalamus, A.N. van den Pol, J. -P. Waurin, and F. Dudek Types of Excitatory Amino Acid Receptors and Their Localization in the Nervous System and Hypothalamus, R.S. Petralia and R.J. Wenthold High-Affinity Glutamate Transporters: Physiological and Pathological Relevance in the Central Nervous System, Y. Kanai and M. Hediger Role of Excitatory Amino Acids in Reproduction, D.W. Brann, L. Ping, P. Zamorano, and V.B. Mahseh Excitatory Amino Acids and the Hypothalamic-Pituitary-Adrenal Axis, C. Oliver, D. Jezova, M. Grino, O. Paulmyer-Lacroix, F. Boudouresque, and P. Joanny Role of Excitatory Amino Acids in Regulation of Growth Hormone Secretion, D. Cocci and L. Cattaneo The Role of Nitric Oxide in the Action of Glutamergic Neurons to Control the Release of Hypothalamic Releasing and Inhibiting Hormones, S.M. McCann Regulation of Circadian Rhythms by Excitatory Amino Acids, C. Cowell and M. Menaker Excitatory Amino Acids and the Control of Seasonal Breeding, H.F. Urbanski The Role of Excitatory Amino Acids in Learning and Memory, S. Baron, J. Auta, and J.M. Moerschbaecher
Genetic analysis of fenugreek (Trigonella foenum-graecum) accessions using morphometric and ISSR markers

In a pilot study, as a prelude for characterization of the entire Trigonella germplasm conserved in the National Gene Bank, National Bureau of Plant Genetic Resources, New Delhi, genetic relatedness among a selection of 49 accessions of fenugreek (Trigonella-foenum-graecum L.) was assessed using 19 morphometric and 186 inter-simple sequence repeat (ISSR) markers. An accession of T. corniculata L. was also assessed as an out-group. The accessions were collected from different eco-geographical sites located in the states of Andhra Pradesh, Himachal Pradesh, Jammu and Kashmir, Madhya Pradesh, Uttar Pradesh, Uttarakhand, Rajasthan, Gujarat, Manipur and Bihar; and one of the accessions was imported from Eritrea. Data for 12 qualitative and seven quantitative morphometric descriptors were recorded. Significant differences within the accessions were found for all the quantitative descriptors except primary branches and seeds/pod. Shannon- Wiener Diversity Index revealed substantial diversity for all the quantitative descriptors. The morphometric data differentiated the fenugreek accessions into two clusters (at ~65% similarity). A total of 100 ISSR primers were used for initial screening, out of which only 21 primers were found polymorphic. ISSR analysis was performed with selected 21 primers to generate 186 amplicons, of which 92.4% were polymorphic. Cluster analysis put 47 accessions in a single group at ~65% similarity. Though there was no agreement between the groupings based on morphometric and ISSR markers (Mantel statistic 0.096), specific cases of geographic groupings were supported by both the markers. Phylogenetic positioning of the accessions with no passport information was found to be possible. The ISSR markers complemented the morphometric data in understanding the genetic divergence among the fenugreek accessions.
An investigation of how middle managers address the balance between autonomous and induced strategic entrepreneurial behaviour in the UAE context

2 DEDICATION . 3 ACKNOWLEDGEMENTS . 4 DECLARATION STATEMENT . 5 List of Figures . 12 List of Tables . 13 Glossary . 14 Chapter 1: Introduction . 18 1.1 Background . 18 1.2 Justification for the Research . 19 1.3 Research Question, the Aims and Objectives of the Research . 19 1.4 Structure of the Thesis . 20 Chapter 2: Literature Review . 22 2.
Enzymatic hydrolysis of various pretreated lignocellulosic substrates and the fermentation of the liberated sugars to ethanol and butanediol

Aspen wood and wheat straw were pretreated by exposure to steam at elevated temperatures. Chemical analysis of the substrates revealed that steam explosion differentially decomposed the pentosan component while leaving the glucan portion relatively unchanged. The pretreated residues could be used as substrates for growth of Trichoderma reesei C30 and T. harzianum E58. The cellulase activities detected were in some cases three times as high as those found when Solka Floc was used as the substrate. Culture filtrates of T. harzianum E58 could efficiently hydrolyze the hemicellulose-rich water-soluble fractions. This material was fermented by Klebsiella pneumoniae with 0.4-0.5 g of 2,3-butanediol produced per gram of sugar utilized. Once the steam-exploded residues had been water and alkali extracted, the enzymatically hydrolyzed substrates were readily fermented by Saccharomyces cerevisiae or Zymononas mobilis with values as high as 2% (w/v) ethanol obtained from 5% steam-exploded wood fractions. 30 references, 2 figures, 8 tables.
Democratic Transactions in the Life Sciences

This article presents an artistic and political experiment as an effort to advance democratic transactions in the life sciences. Artists built a ‘gender democratic labyrinth’ in Maastricht, in which scientists, women’s groups, people in general, artists, philosophers, politicians, journalists, clinical geneticists and many others interacted and negotiated on the creation of human embryos for medical-scientific research (a subject kept open in the Dutch Embryo Law of September 2002 to decide within a few years). By taking a gender perspective on the process of democratizing science, we aimed to create a space in which alterity and difference are constitutive elements in the public exchanges on science and technology. The idea to build a labyrinth was theoretically based on the notion of agonistic democracy - in which pluralism is the result of contestations and divisions - and on a notion of science and technology as being contextualized and socialized.
Energy Use and Growth of Manufacturing Sector: Evidence from Turkey

This study investigates the relationship between Energy use and the growth of the Turkish Manufacturing Sector, using Vector Error Correction and Granger causality, between 1960 and 2015. The research found a long-run association among these variables. However, while the VEC granger causality test result suggests no causality running, either direction, from predetermined Energy Use to Growth in Manufacturing Sector, the Variance decomposition and impulse response tests suggested a positive causality, running from contemporaneous values Energy Use to current and future values of Growth in the Manufacturing Sector of Turkey. It is recommended that more investments be made in the energy sector to help sustain the current performance in the manufacturing sector.
Immune function and infection status is related to migration distance and phases of the annual cycle in song sparrows (Melospiza melodia)

ii List of Tables vi List of Figures vii List of Appendices ix 1 Literature Review and Introduction 1 1.1 Host-parasite interactions and vertebrate immunity 1 Avian blood-borne parasites 1 Effects of blood-borne parasites on host fitness. 2 Innate and acquired immunity 3 Quantifying immunocompetence 5 Costs of immunity 6 The annual cycle and immunity 7 1.2 Avian Migration 9 Why migrate? 9 Intraspecific variation in avian migration 11 Causes of partial and differential migration 13 Maintaining intraspecific variation 15 Costs of migration 16 Evaluating avian migration distance 17 Migration and parasite risk 20 Migration and immunity 21 1.3 Objectives and Hypotheses 23 Study system 23 Hypotheses and predictions 24 2 Materials and methods 28 2.1 Study site, animals, and sample collection 28 2.2 Immune assays 30 Phagocytosis assay 30 Hemolysis and hemagglutination assay (HL/HA) 32 ELISA immunoglobulin Y (IgY) assay 33 2.3 Blood smear analysis 35
Maternal lineages in polyploid wheat species inferred from organeller DNA fingerprinting

To understand the origin of polyploid wheat species from the view point of maternal lineage, we have been studying the molecular variation of organellar genomes using DNA fingerprinting techniques. Chloroplast and mitochondrial microsatellites were used to study intraspecific variation of Triticum and related Aegilops species. Surveys in free-threshing emmer and common wheat indicated that only one of the two maternal lineages in non-free-threshing emmer wheat was transferred to free-threshing common wheat. Chloroplast DNA variation in wild and domesticated timopheevi (T. timopheevi) wheat suggested the monophyletic origin of domesticated timopheevi wheat. Molecular variation in mitochondrial DNA in Ae. speltoides revealed the contrasting variability between chloroplast and mitochondrial genome.
Germination of 2 legumes in leachate from introduced grasses.

Kleberg bluestem [Dichmthium annuktum (Forsk.) StaprJ and buffelgrass (Cmeluus ciIiur& L.) may produce pbytotoxic cbemicals that inbibit germbtation and growth of legumes planted in s&g mixtures with grasses. We determined the effects of leacbate from these introduced grasses on seed germination of Illinois bundleflower [Desmanthusilifuoens&(Michx.) MacM. ] and partridge pea (Carsia~arciculoro Michx.). Percent germination of Illinois bundleflower seeds on substrata moistened with Kleberg bluestem root or buffelgrass leaf leacbate was lower than that of seeds placed on substrata moistened with distilled water. Buffelgrass root Ieacbate reduced germination of partridge pea more than did root leacbate from Kleberg bluestem or leafleacbate from Kleberg bluestem or buffelgrass. Results of these laboratory experiments bulicate that field studies are warranted to determine the effects of buffelgrass on establishment of partridge pea and Illinois bundleflower in order to help land managers select the optimum combination of species for rangeland seeding.
First record of the unicorn leatherjacket Aluterus monoceros (Tetraodontiformes: Monacanthidae) from the Southern coast of Bay of Bengal, Bangladesh

We report the first record of the unicorn leatherjacket Aluterus monoceros (Tetraodontiformes: Monacanthidae) from the Southern coast of Bay of Bengal, Bangladesh. A single specimen of A. monoceros was collected on 03 March 2018, from the Alipur Fish Landing Center of Kuakata, Bangladesh. Morphometric and molecular approach were applied for taxonomic identification. Body compressed with leathery skin almost oval in shape, a long pointed snout. Caudal peduncle is longer than deep; peduncle length into peduncle depth 0.66 times. Caudal fin relatively short, about 15% of standard length (SL). Eye to dorsal spine distance relatively large, 7.63% of S.L. Body depth is 38.5% of S.L. The morphometric, meristic and DNA barcoding data thus confirmed the presence of A. monoceros in Bangladesh. This report updates the geographical distribution for this species confirming its presence in the coastal region of Bangladesh, and extends the number of marine fish known from the area.
Self-assembling complexes for gene delivery : from laboratory to clinical trial

Partial table of contents: PRINCIPLES OF SELF-ASSEMBLY. Polymorphism of Lipids, Nucleic Acids, and their Interactions (D. Lasic, et al.). Self-Assembly of Bacteriophage (M. Burbea P. Prevelige). NATURAL MECHANISMS FOR GENE-DELIVERY TO CELLS. Endocytosis: An Overview (V. Slepnev P. De Camilli). NOVEL SYSTEMS USING CATIONIC LIPOSOMES. Novel Supramolecular Assemblies for Gene Delivery (F.-P. Yang L. Huang). POLYELECTROLYTE DNA COMPLEXES. Cationic Block Copolymers as Self-Assembling Vectors for Gene Delivery (L. Seymour, et al.). Cellular Internalization and Fate of Polycation-DNA Complexes (C. Pouton, et al.). SYSTEMIC BIODISTRIBUTION OF DRUG DELIVERY SYSTEMS. In Vitro and In Vivo Availability of Liposomes (V. Torchilin). TARGETING OF CONJUGATES FOR GENE DELIVERY. Polylysine-Conjugate Based DNA Delivery (E. Wagner). Peptides and Fusion Proteins as Modular DNA Carriers (W. Wels J. Fominaya). NEW APPORACHES TO GENE DELIVERY. Semi-Synthetic Systems for Gene Delivery (C. Hodgson, et al.). CLINICAL EVALUATION. Cystic Fibrosis Clinical Trials (D. Geddes E. Alton). Index.
Développement du pancréas humain embryonnaire ex vivo / in vivo : La greffe musculaire : un nouveau modèle d'étude longitudinale et dynamique

Au-dela de l’interet cognitif de la demarche, la comprehension des mecanismes qui regissent le developpement pancreatique humain reste la cle pour decrypter les acteurs physiopathologiques des maladies du pancreas et pour developper des approches therapeutiques innovantes. En outre, alors que la cellule beta de rongeurs et la cellule beta humaine partagent un grand nombre de similitudes, certaines donnees indiquent egalement des differences marquees entre les especes. L'absence de systemes experimentaux robustes , a partir de materiel humain, n'a pas permis un examen detaille du developpement pancreatique humain jusqu’a present. Dans le laboratoire, il a ete precedemment valide un modele de xenogreffe de pancreas immature humain sous la capsule renale de souris immuno-incompetentes SCID. Il a ete demontre que celui-ci permettait de recapituler l’ensemble des etapes du developpement endocrine humain. Neanmoins le site de greffe limitait les possibilites de modifier ce developpement, notamment par infection virale. Dans ce travail, nous avons developpe et valide un nouveau site de greffe dans le muscle squelettique, plus simple et plus superficiel. En outre, nous demontrons qu’il est possible de creer un pancreas humain partiellement transgenique in vivo en realisant du transfert de genes medie par des lentivirus, apres injection directe de la solution virale dans le greffon. Ce modele de greffe dans le muscle est une nouvelle approche permettant d’envisager des etudes longitudinales, dans lesquelles il serait possible d’etudier la regulation de certains genes ou le devenir de certaines lignees marquees par des genes rapporteurs apportes par le virus a differents stades de developpement.