Miracle-dz/UniFAR-FTUs huggingface dataset:
Measuring lumbar spinal motion during functional activities with the Epionics SPINE system: a comparative evaluation and reliability study

Quantifying spinal motion during functional activities may contribute to a better understanding of common pathologies such as spinal disorders. Therefore, the current study aimed at the comparative evaluation of the Epionics SPINE system, a portable and cost-effective device for measuring sagittal lumbar movement during functional activities. Twenty healthy participants were therefore evaluated with the Epionics SPINE and a Vicon motion analysis system in two identical separate research visits. They performed the following activities: standing, sitting, chair rising, box lifting, walking, running and a counter movement jump (CMJ). Sagittal plane lumbar spine angles were extracted as continuous values as well as average and range of motion (ROM) parameters. Agreement between the systems was evaluated using Bland-Altman analyses, whereas within- and between-session reliability were assessed using intraclass correlation coefficients (ICC) and minimal detectable changes (MDC). The analysis showed excellent agreement between the systems for chair rising, box lifting and CMJ with a systematic underestimation of lumbar lordosis angles during walking and running. Reliability was moderate to high for all continuous and discrete parameters (ICC>=0.62), except for ROM during running (ICC=0.29). MDC values were generally below 15°, except for CMJ (peak values up to 20° within and 25° between the sessions). The Epionics SPINE system performed similarly to a Vicon motion capture system for measuring lumbar lordosis angles during functional activities and showed high consistency within and between measurement sessions. These findings can serve researchers and clinicians as a bench mark for future investigations using the system in populations with spinal pathologies.
High-Content Phenotypic Profiling in Esophageal Adenocarcinoma Identifies Selectively Active Pharmacological Classes of Drugs for Repurposing and Chemical Starting Points for Novel Drug Discovery

Esophageal adenocarcinoma (EAC) is a highly heterogeneous disease, dominated by large-scale genomic rearrangements and copy number alterations. Such characteristics have hampered conventional target-directed drug discovery and personalized medicine strategies, contributing to poor outcomes for patients. We describe the application of a high-content Cell Painting assay to profile the phenotypic response of 19,555 compounds across a panel of six EAC cell lines and two tissue-matched control lines. We built an automated high-content image analysis pipeline to identify compounds that selectively modified the phenotype of EAC cell lines. We further trained a machine-learning model to predict the mechanism of action of EAC selective compounds using phenotypic fingerprints from a library of reference compounds. We identified a number of phenotypic clusters enriched with similar pharmacological classes, including methotrexate and three other antimetabolites that are highly selective for EAC cell lines. We further identify a small number of hits from our diverse chemical library that show potent and selective activity for EAC cell lines and that do not cluster with the reference library of compounds, indicating they may be selectively targeting novel esophageal cancer biology. Overall, our results demonstrate that our EAC phenotypic screening platform can identify existing pharmacologic classes and novel compounds with selective activity for EAC cell phenotypes.
Dashboard Executive Information System dengan Pendekatan Sistem Terdistribusi untuk Pemantauan Penyaluran Kredit KUR Mikro Bank X

KUR Mikro (Kredit Usaha Rakyat) adalah variasi produk kredit yang disalurkan oleh kantor-kantor unit bank dengan target penyaluran berbeda-beda untuk setiap unitnya. Pencapaian target penyaluran di kantor unit dipantau oleh kantor cabang, sehingga diperlukan sistem yang dapat menangani hal tersebut. Dashboard Executive Information System dengan pendekatan terdistribusi dapat digunakan untuk memantau target pencapaian penyaluran KUR Mikro di setiap kantor unit Bank X. Web service digunakan untuk menjembatani komunikasi pada sistem terdistribusi. Dashboard Executive Information System digunakan oleh kepala cabang untuk memantau grafik data nasabah KUR Mikro. Kepala cabang dapat memantau perbandingan pencapaian target jumlah nasabah antar kantor unit pada sistem. Dashboard Executive Information System dapat berinteraksi dengan tiga entitas yaitu admin, kantor cabang dan kantor unit. Web Dashboard Executive Information System terdiri dari 17 halaman yang digunakan untuk manajemen data. Hasil pengujian dan analisa menunjukkan seluruh halaman web serta sinkronisasi berupa data nasabah, data pemohon, data pencairan dan data pembayaran kredit usaha rakyat dapat digunakan dengan status uji sukses. Kata Kunci: web service, Dashboard Executive Information System, KUR
Vision‐based approach for predicting the probability of vehicle–pedestrian collisions at intersections

Road accidents impose serious problems on society. Possible collisions between vehicles and pedestrians must be detected before they occur so that a timely warning may be issued. By using the vision-based approach, this study presents an effective and efficient algorithm to estimate the vehicle-pedestrian collision probability at intersections. The real-time trajectories and movement parameters (position, speed, acceleration or direction) of vehicles and pedestrians are obtained based on state-of-the-art detection and tracking algorithm which include background subtraction method, faster regions with convolutional neural networks and optical flow method. To find the appropriate time to identify the latent collision risk for calculating the collision probability, this study defines the critical time based on different collision patterns of perception-reaction failure and evasive action failure. In addition, based on discrete acceleration and discrete angle, the authors get different extended trajectories which can include most situation when the conflict happened. Trajectories generation probability are given by the discrete choice probability model based on the Logit model to get the accurate collision probability. Real-world video data is implemented to demonstrate the approach. This proposed collision prediction method can provide some important results for designing the intelligent pedestrian signal timing schemes at intersections.
Characterization of Space and Time-Dependence of 3-Point Shots in Basketball

Understanding characteristics of 3-point shots is paramount for modern basketball success, as in recent decades, 3-point shots have become more prevalent in the NBA. They accounted for 33,6% of the number of total shots in 2017-2018, compared to only 3% in 1979-1980. In this paper, we aim at better understanding the connections between the type of 3-point shooting (catch-and-shoots and pull-ups) and the timing for shooting, using two distinct space-time models of player motion. Those models allow us to identify individual behavior as a function of specific defensive settings, e.g. shot-behavior when a player is guarded closely. We assess our models using SportVU data for specific NBA players and our code is open-source to enable more players and teams explorations, as well as to support further research and application of those models, beyond basketball and sport.
On variable splitting for Markov chain Monte Carlo

Variable splitting is an old but widely used technique whichaims at dividing an initial complicated optimization problem into simplersub-problems. In this work, we take inspiration from this variable splitting idea in order to build efficient Markov chain Monte Carlo(MCMC) algorithms. Starting from an initial complex target distribution,auxiliary variables are introduced such that the marginal distributionof interest matches the initial one asymptotically. In addition to havetheoretical guarantees, the benefits of such an asymptotically exact dataaugmentation (AXDA) are fourfold: (i) easier-to-sample full conditionaldistributions, (ii) possibility to embed while accelerating state-of-the-artMCMC approaches, (iii) possibility to distribute the inference and (iv)to respect data privacy issues. The proposed approach is illustrated onclassical image processing and statistical learning problems.
High Performance Water-based Drilling Fluids—A High Efficiency Muds Achieving Superior Shale Stability While Drilling Deepwater Well with HPHT in South China Sea

In deepwater drilling operation, low temperature, high pressure, gas hydrate, narrow density window are the major challenges for drilling fluids to meet, and with the increasing depth drilled, high temperature and high pressure condition was occurred in deepwater well. In the other side, Oil based muds (OBM) and synthetic based muds (SBM) are limited in using because of the strict environment rules in the South China Sea. In deepwater HTHP well, shale hydration, dispersion and Equivalent Circulation Density (ECD) caused by rheology change with high temperature difference are the two critical problems. Therefore, petroleum service institutes and companies take much time and money on research to develop a high performance water-based mud system (HPWBM) to solve these problems and improve drilling efficiency. In the paper, a new method to estimate amine derivatives was proposed, the specific test steps was introduced in detail, and secondly a High efficiency muds (HEM) are selected and the main properties were evaluated in lab such as rheological properties at lower temperature, shale inhibition and anti-accretion. Finally, the system was applied successfully in LS project in the South China Sea. The results showed that HEM system delivered high drilling performance such as shale stability, high pressure and high temperature (HPHT) resistance, lubricity and high rate of penetration (ROP) with no wellbore problems, and the system is suitable for deepwater HTHP well operation.
Social Stratification and Leisure Consumption: Empirical Evidence Based on Micro Survey Statistics in China

This paper empirically analyzes the impact of social stratification of Chinese residents on leisure consumption. Based on the data from 2016 Chinese Family Panel Studies (CFPS), the regression results of instrumental variables show that the social level of Chinese residents has a significant positive impact on leisure consumption, considering the endogenous possibility of social stratification on leisure consumption. The policy implication of this paper is that when launching policies related to the cultural industry and leisure consumption, responsible departments of Chinese government should fully consider the possibility and complexity of the influence of Social stratification on the effectiveness of policies.
The Effect of Earnings Quality on Cost of Equity Through Information Asymmetry: An Empirical Study of the Manufacturing Companies in the Indonesia Stock Exchange

This research examines the effect of earnings quality on the cost of equity and whether information asymmetry affects the relationship as a mediator. A hundred and twenty-three manufacturing companies listed in the Indonesia Stock Exchange during 2007-2012 were selected through a purposive sampling method. This study uses absolute discretionary accruals (|DA|) to measure earnings quality, bid-ask spread to proxy information asymmetry, and CAPM to measure the cost of equity. Using the bootstrapping method in the hypotheses testing, this study finds a significant negative effect of earnings quality on the information asymmetry. However, there is no support on the positive association between information asymmetry and the cost of equity, as well as the role o f information asymmetry as a mediator on the negative association between earnings quality and cost of equity.
Impact of Depression on Pathologic Internet Use Among Intern Doctors of Cairo University Hospital (Kasr Al-Ainy)

Introduction:The growth of the internet has impacted almost every facet of life in the world. In most cases, utilization of the internet has improved people’s lives. However, in some cases excessive use of the internet has been linked to significant impairment in critical areas of functioning. Aim of the Work:To determine the prevalence of pathologic use of the internet and verify whether there is a relation between this problem and the depressive disorders among Intern doctors working in Cairo University hospital. Subjects and Methods:A total of 300 Intern doctors of Cairo University hospitals were included. The Internet Addiction Test was used to measure pathologic intent use. Present State Examination-10 was used for screening of depressive symptoms and Beck Depression Inventory to determine the severity of depression. The Internet Application Checklist was used to determine internet usage patterns of the subjects. Results:More than half of the sample (54.0%) consisted of pathologic internet users. Only 12.3% comprised moderate/severe pathologic internet users. Severe forms of pathologic internet use were more prevalent in male individuals than in female individuals. Pathologic internet users were more associated with depressive symptoms and depressive disorders than nonpathologic internet users. Conclusions:There were significant positive correlations among internet addiction, depressive symptoms, and depressive disorders in fresh graduate Cairo University Intern doctors. As there is a potential harmful behavior among new graduate doctors, health professionals need to be aware of measures and procedures for the assessment of internet addiction and depression.
Millimeter-Wave Dual-Polarized Filtering Antenna for 5G Application

This article presents a novel dual-polarized millimeter-wave (mm-Wave) patch antenna with bandpass filtering response. The proposed antenna consists of a differential-fed cross-shaped driven patch and four stacked parasitic patches. The combination of the stacked patches and the driven patch can be equivalent to a bandstop filtering circuit for generating a radiation null at the upper band edge. Besides, four additional shorted patches are added beside the cross-shaped driven patch to introduce another radiation null at the lower band edge. Moreover, by embedding a cross-shaped strip between these four stacked patches, the third radiation null is generated to further suppress the upper stopband. As a result, a quasi-elliptic bandpass response is realized without requiring extra filtering circuit. For demonstration, a prototype was fabricated with standard PCB process and measured. The prototype operates in the 5G band (24.25–29.5 GHz) and it has an impedance bandwidth of 20%. The out-of-band gain drops over 15 dB at 23 and 32.5 GHz, respectively, which exhibits high selectivity. These merits make the proposed antenna a good element candidate for the 5G mm-Wave massive MIMO applications to reduce the requirements of the filters in the mm-Wave RF front ends.
Margins of Fair Trade Wine along the Supply Chain: Evidence from South African Wine in the U.S. Market

Abstract In this paper, we analyze profit margins and markups of Fair Trade (FT) wines sold in the United States. We are particularly interested in whether and to what extent the FT cost impulse in production is passed along to the supply chain. We draw on a limited sample of about 470 South African wines sold in Connecticut and New Jersey in the fall of 2016; about 90 of them are certified FT. For these wines we have free on board export prices, wholesale prices, and retail prices, which allows us to compute wholesale and retail margins and analyze the FT treatment effect. We run OLS, 2SLS, and propensity score matching models and find evidence of asymmetrical pricing behavior. While wholesalers seem to fully pass-through the FT cost effect, retailers appear to amplify the cost effect. As a result, at the retail level, FT wines yield significantly higher margins than their non-FT counterparts. (JEL Classifications: L11, L31, L43, L81, Q17)
Sys-TM: A Fast and General Topic Modeling System

Topic models, such as LDA and its variants, are popular probabilistic models for discovering the abstract “topics” that occur in a collection of documents. However, the performance of topic models may vary a lot for different workloads, and it is not a trivial task to achieve a well-optimized implementation. In this paper, we systematically study all recently proposed samplers over LDA: AliasLDA, F+LDA, LightLDA, and WarpLDA, and discover a novel system tradeoff by considering the diversity and skewness of workloads. Then, we propose a hybrid sampler which can cleverly choose an efficient sampler with the tradeoff, and apply the hybrid sampler to LDA and its variants, including STM, TOT and CTM. Finally, we build a fast and general topic modeling system Sys-TM, which provides a unified topic modeling framework by integrating the hybrid sampler. Based on our empirical studies, the hybrid sampler outperforms the state-of-the-art samplers by up to <inline-formula><tex-math notation="LaTeX">$2\times$</tex-math> <alternatives><mml:math><mml:mrow><mml:mn>2</mml:mn><mml:mo>×</mml:mo></mml:mrow></mml:math><inline-graphic xlink:href="shao-ieq1-2956518.gif"/></alternatives></inline-formula> over various topic models, and with carefully engineered implementation, Sys-TM is able to outperform the existing systems by up to <inline-formula><tex-math notation="LaTeX">$10\times$</tex-math> <alternatives><mml:math><mml:mrow><mml:mn>10</mml:mn><mml:mo>×</mml:mo></mml:mrow></mml:math><inline-graphic xlink:href="shao-ieq2-2956518.gif"/></alternatives></inline-formula>.
Struktur Sebaran Ruang Terbuka Hijau di Kota Makassar

Penelitian ini bertujuan untuk menganalisis ruang terbuka hijau di Kota Makassar dari aspek luasan dan struktur penyebarannya. Alat ukur yang dipergunakan untuk melihat ketersediaan dan penyebaran adalah Permen PU Nomor 5 Tahun 2008. Penelitian ini dilakukan dengan metode survei dengan analisis deskriptif. Teknik analisis mempergunakan tabel persentase dan tabel skalogram. Data dikumpulkan dengan teknik observasi, wawancara terstruktur dan penyebaran kuesioner serta dokumentasi. Hasil penelitian menunjukkan bahwa kondisi ruang terbuka hijau di Kota Makassar luas dan sebarannya tidak terstruktur mengikuti perkembangan planologis kota. Tiga Kecamatan yang menjadi sampel hanya Kecamatan Ujung Pandang yang mempunyai struktur ruang terbuka hijau yang terpola mengikuti perkembangan pola planologis kota. Sedangkan dua kecamatan lainnya yakni Kecamatan Makassar dan Kecamatan Bontoala tidak mempunyai pola struktur RTH. Kompleks RTH Lapangan Karebosi sebagai RTH tingkat kota luasannya tidak sesuai berdasarkan jumlah penduduk, tingkat pemenuhannya sebesar 18 persen. RTH tingkat kelurahan, dari 12 kelurahan yang menjadi hanya 6 kelurahan yang mempunyai RTH. Fasilitas RTH Tingkat RW dan RT selain RW dan RT yang ditempati RTH tingkat kota, kecamatan dan kelurahan, pada tempat lain tidak ditemukan. Berdasarkan analisis skalogram persentase penyebaran RTH (COR) adalah 24 persen.
Within-group spatial position and activity budget of wild sooty mangabeys (Cercocebus atys) in Taï National Park, Côte d’Ivoire

Within social groups, feeding competition and predation pressure affect individual spatial position. The costs and benefits associated to each position are likely to influence the time that individuals allocate to different activities. Whether the effect of spatial positioning on activity budget differs between individuals of different sex or dominance rank remains unclear. This study aimed at investigating the effect of within-group spatial position on the activity budget of male and female sooty mangabeys. Focal behavioral observations was used to collect the individual location and behavior every 15 minutes (N=5115 locations) on 29 individuals from a wild group of sooty mangabeys (Cercocebus atys) in the Tai National Park. The joint effect of rank, sex and spatial position on individual‟s activity budget was investigated. Females were more central in the group and both fed and rested more than males, independently of their rank. High-ranking individuals from both sexes were more likely to be central and both fed and rested longer than low-ranking ones. Females and high-ranking individuals from both sexes benefit from their social status by adopting spatial positions in the community that could influence their fitness positively. These results are discussed to improve our understanding of social dynamics in wild primates. Keywords : Spatial position, primates, socio-ecology, social dynamics.
In-package cold plasma decontamination of fresh-cut carrots: microbial and quality aspects

Cold plasma is a promising nonthermal technology for the decontamination and preservation of fresh and fresh-cut produce. The rapid action of a cocktail of reactive oxygen and nitrogen species in plasma against a variety of food spoilage and pathogenic organisms make it a suitable decontamination intervention. This study evaluates the effectiveness of high voltage atmospheric cold plasma in reducing the natural microflora of carrots treated at 60, 80, and 100 kV (60 Hz frequency) for 1, 2, 3, 4, and 5 min. About 2 log10 CFU/g reduction in the population of both, total aerobic mesophiles, and yeast and mold was observed in carrot discs treated at 100 kV for 5 min (~250 W power). The changes in pH, colour, texture, and total carotenoids of cold plasma treated carrots were minor. For shelf-life evaluation of plasma treated cut-carrots voltages between 80 to 100 kV and treatment times between 4 to 5 min is recommended, such that reduction in spoilage microflora and quality retention is maximized. Voltage was found to have a significant effect on the total carotenoids and colour of the carrot discs. Further optimization of the process parameters, preferably using modified gases, is necessary to balance the desired reduction in microflora versus the quality retention.
Autonomic reactivity in premenopausal, perimenopausal and postmenopausal Women

The autonomic nervous system controls most of the visceral functions of the body through the sympathetic and the parasympathetic nerve fibers. In postmenopausal women, the risk of cardiovascular diseases gradually increases and alterations in autonomic nerve functions commonly affect cardiac vagal control. In women, the withdrawal of the hormones in the perimenopausal and the menopausal period is gradual. The present study was aimed to assess the autonomic functions in premenopausal, perimenopausal and postmenopausal women. This study was conducted on 210 women volunteers, who were divided into three groups of 70 each, namely Group I (premenopausal), Group II (perimenopausal) and Group III (postmenopausal). The sympathetic function tests performed were blood pressure, blood pressure response to standing (orthostasis) and the isometric handgrip strength test (IHST). The parasympathetic tests conducted were standing to lying (S/L) ratio, 30:15 ratio, valsalva ratio and tachycardia ratio. All parameters were reported as mean and standard deviation. The study concluded that there is predominant sympathetic activity in postmenopausal women in comparison to premenopausal women. Parasympathetic activity altered slightly but not significantly in postmenopausal women. Keywords: Autonomic nervous system, Postmenopausal, Sympathetic, Parasympathetic, Nerve fibers, Cardiac vagal control