Miracle-dz/UniFAR-FTUs huggingface dataset:
Quality-of-Experience (QoE) in Emerging Mobile Social Networks

Mobile social networks (MSN) provides diverse services to meet the needs of mobile users, i.e., discovering new friends, and sharing their pictures, videos and other information among their common interest friends. On the other hand, Quality-of-Experience (QoE) is a new concept related to but differs from Quality-of-Service (QoS) perception. QoE is a subjective measure of a customer’s experiences with a service focuses on the entire service experience, and is a more holistic evaluation. So far, QoS issues have been focused and mainly addressed in the literature of MSNs. To the best of our knowledge, this paper is the first article to address QoE issues in emerging MSNs. In this paper, we first present a comprehensive investigation on recent advances in MSNs as well as QoE issues addressed in various types of applications and networks. From the lessons learned from the literature, then we propose a future research direction of QoE in MSNs. key words: mobile social network, quality of experience, survey
Characterization of DNA adducts formed by anti-benzo[g]chrysene 11,12-dihydrodiol 13,14-epoxide.

The anti-11,12-dihydrodiol 13,14-epoxide of benzo[g]chrysene, a fjord-region-containing hydrocarbon, was found to react with DNA in vitro to yield, as the major product, an adduct in which the epoxide of the 11R, 12S, 13S, 14R enantiomer was opened trans by the amino group of deoxyadenosine. The structures of this adduct and other deoxyadenosine and deoxyguanosine adducts were established by spectroscopic methods. In reactions with deoxyguanylic acid, a product tentatively identified as a 7-substituted guanine was also detected. The mutagenic properties of this dihydrodiol epoxide in shuttle vector pSP189 showed that mutation at AT pairs accounted for 39% of base change mutations whereas chemical findings indicated that about 60% of adducts formed in calf thymus DNA involved adenines. Since calf thymus DNA is 56% AT and the target supF gene is 41% AT, the findings represent a fairly close relationship between adduct formation and mutagenic response. Overall, the chemical and mutagenic selectivities for the two purine bases in DNA were similar, though not identical, to those for the only other fjord-region-containing hydrocarbon studied in depth, i.e., benzo[c]phenanthrene. A major difference for these two hydrocarbon derivatives, however, is that benzo[c]phenanthrene dihydrodiol epoxides react to much higher extents (approximately 4-fold) with DNA than did the benzo[g]chrysene derivative.
The Dysvascular Foot: A System for Diagnosis and Treatment

Orthopaedic treatment of the dysvascular foot and ankle can be frustrating, disheartening, difficult, impossible, and yet satisfying and rewarding. Amputation, that most dreaded of all clinical procedures, is most often caused by circulatory disturbances. Dysvascular patients make up 80% of the thousands of patients who undergo lower extremity amputation each year.3. 46 Of this group, 50 to 70% are now
Presensitization to HY antigens in female donors prior to transplant is not associated with male recipient post-transplant HY antibody development nor with clinical outcomes

It has been shown that chronic graft-versus-host disease (cGVHD) incidence is significantly increased in male recipients receiving allogeneic hematopoietic cell transplant from female donors (F→M HCT). 1,2 B cell immunity plays a critical role in cGVHD development,3,4 and we have so far investigated clinically relevant immune responses against minor antigens encoded by the Y-chromosome (HY antigens) following F→M HCT.5–7 Recently, we have demonstrated that in F→M HCT, antibody responses against HY antigens (HY-Ab) are correlated with cGVHD and that the cumulative number of HY-Abs three months post-HCT could significantly predict cGVHD development and non-relapse mortality.8
A gradient-based nested Latin hypercube DOE for quadratic polynomials RSM in FEM simulation

A nested Latin hypercube DOE (Design Of Experiment) involves at least a low accuracy experiments and a high accuracy one in Finite Element Method (FEM) Simulation. How to use the information contained in the regression model of previous low accuracy experiments in the design of high accuracy one needs deeply study because such information may be ignored in evenly sampling method, leading to a imprecise regression model of high accuracy experiment. This paper employ the gradient of the regression model of low accuracy experiments as the index of the information distribution of tested object to adjust the DOE of high accuracy one. Thus more information of object can be obtained in those high accuracy experiments and a more precise quadratic polynomials RSM (Response Surface Method) model is built.
Dipole estimation errors due to not incorporating anisotropic conductivities in realistic head models for EEG source analysis

EEG source analysis is a valuable tool for brain functionality research and for diagnosing neurological disorders, such as epilepsy. It requires a geometrical representation of the human head or a head model, which is often modeled as an isotropic conductor. However, it is known that some brain tissues, such as the skull or white matter, have an anisotropic conductivity. Many studies reported that the anisotropic conductivities have an influence on the calculated electrode potentials. However, few studies have assessed the influence of anisotropic conductivities on the dipole estimations. In this study, we want to determine the dipole estimation errors due to not taking into account the anisotropic conductivities of the skull and/or brain tissues. Therefore, head models are constructed with the same geometry, but with an anisotropically conducting skull and/or brain tissue compartment. These head models are used in simulation studies where the dipole location and orientation error is calculated due to neglecting anisotropic conductivities of the skull and brain tissue. Results show that not taking into account the anisotropic conductivities of the skull yields a dipole location error between 2 and 25 mm, with an average of 10 mm. When the anisotropic conductivities of the brain tissues are neglected, the dipole location error ranges between 0 and 5 mm. In this case, the average dipole location error was 2.3 mm. In all simulations, the dipole orientation error was smaller than 10°. We can conclude that the anisotropic conductivities of the skull have to be incorporated to improve the accuracy of EEG source analysis. The results of the simulation, as presented here, also suggest that incorporation of the anisotropic conductivities of brain tissues is not necessary. However, more studies are needed to confirm these suggestions.
Physical characterisation of high-k gate stacks deposited on HF-last surfaces

By the combination of the analysis results of different complementary analysis techniques a methodology is established for the consistent determination of the growth curves for the ALCVD deposition of ZrO/sub 2/ and Al/sub 2/O/sub 3/ on HF-last surfaces. Consistency between all data requires the assumption of a lower film density than the bulk one of the different materials. The lower density is also determined independently by X-ray reflectivity (XRR) and is consistent with the thickness as determined by cross-section TEM.
DESIGN AN AGING-AWARE RELIABLE H-MULTIPLIER 1

This paper presents the design an H-Logic[H.L] multiplier for 32*32bit number multiplication. Modern computer system is a dedicated with very high speed unique multiplier. Therefore, this paper presents the design an H-Logic multiplier. The proposed system generates M, N and X blocks. By extending bit of the operands and generating an additional product the H-Logic multiplier is obtained. Multiplication operation is performed by the H-Logic is efficient with the less area anditgives the reduces delay i.e., speed is increased.
Enteropathogenic Escherichia coli Type III Effectors EspG and EspG 2 Disrupt the Microtubule Network of Intestinal Epithelial Cells

Enteropathogenic Escherichia coli Type III Effectors EspG and EspG2 Disrupt the Microtubule Network of Intestinal Epithelial Cells Robert K. Shaw,† Katherine Smollett,† Jennifer Cleary, Junkal Garmendia, Ania Straatman-Iwanowska, Gad Frankel, and Stuart Knutton* Institute of Child Health, University of Birmingham, Birmingham B4 6NH, and Centre for Molecular Microbiology and Infection, Department of Biological Sciences, Imperial College London, London SW7 2AZ, United Kingdom
Control of nonlinear systems with output tracking error constraints and its application to magnetic bearings

A constructive method is presented to design controllers that force the output of nonlinear systems in a strict feedback form to track a bounded and sufficiently smooth reference trajectory asymptotically. Under a suitable condition on the initial output tracking error, the proposed controllers guarantee the output tracking error within a symmetric or an asymmetric pre-specified limit range, and boundedness of all signals of the closed-loop system. A transformation is introduced to take care of the output tracking error constraint. Smooth and/or p-times differentiable step functions are proposed and incorporated in the output tracking error transformation to overcome difficulties due to the asymmetric limit range on the output tracking error. As a result, there are no switchings in the proposed controllers despite the asymmetric limit range. The proposed control design is then applied to design a tracking controller for active magnetic bearings as an illustrating application.
The Tat Protein of Human Immunodeficiency Virus Type 1 Is a Substrate and Inhibitor of the Interferon-induced, Virally Activated Protein Kinase, PKR*

We demonstrate that the interferon-induced, double-stranded (ds) RNA-activated kinase, PKR, is able to bind to and phosphorylate the human immunodeficiency virus type 1 (HIV-1) trans-activating protein, Tat. Furthermore, Tat can inhibit the activation and activity of the kinase. Phosphorylation of Tat by PKR is dependent on the prior activation of PKR by dsRNA and occurs on serine and threonine residues adjacent to the basic region important for TAR RNA binding and Tat function. Activated PKR efficiently phosphorylates both the two-exon form of Tat (Tat-86) and the single exon form (Tat-72). Mutagenesis indicates that the interaction between PKR and Tat requires the RNA-binding region of Tat. Tat competes with eukaryotic initiation factor 2, a well-characterized substrate of PKR, for phosphorylation by activated PKR. Tat also inhibits the autophosphorylation of PKR by dsRNA. This biochemical evidence of an intimate relationship between Tat, an important regulator of HIV transcription, and PKR, a pleiotropic cellular regulator, may provide insights into HIV-1 pathogenesis and, more generally, virus/host interactions.
Comparison of indigestible markers from in situ and in vivo incubation to predict apparent digestibility in hay- and corn-fed horses - 10.4025/actascianimsci.v34i1.10572

Four castrated crossbred horses were used in a randomized block design to study the use of indigestible internal markers iNDF and iADF obtained in situ (from bovines) or in vivo (from equines). Treatments consisted of determining digestibility by the direct method comprising total feces collection (TC) and by the indirect method comprising internal markers iNDF and iADF obtained by in situ incubation in bovine rumen or in vivo by the mobile nylon bag (MNB) technique with horses. iNDF-IV and iADF-IV resulted in better marker recovery rate (RR) (91.50%), similar to TC. The in situ technique resulted in lower RR values for the two indigestible markers, averaging 86.50% (p < 0.05). Estimates of the nutrient coefficient of digestibility (CD) were adequately predicted by iADF-IV, for horses fed on hay exclusively, with rates 46.41, 48.16, 47.92 and 45.51% for dry matter (DM), organic matter (OM), FDN and gross energy, respectively. Results show that MNB may be used to obtain iADF in horses fed on coast-cross hay exclusively, whereas NDFi and ADFi were selected for horses fed on mixed diets to predict the coefficient of nutrient digestibility
Experiments with time delay networks and dynamic time warping for speaker independent isolated digits recognition

We descrtbe in thls paper a speaker Independent. global word recognition task ustng time delay networks. We flrst descrtbe these networks as a way for leamlng feature extractors by constralned back-propagatlon. Such a tlme-delay network ls shown to be capable of deallng wlth a test task: French dlgtt recognttlon. The results are dlscussed and compared, on the same data sets, wlth those obtained wlth a classlcal time warping system. Both connectlonlst and classlcal systems achieved no more than 1% errors on the test set
Cortico–Amygdala–Striatal Circuits Are Organized as Hierarchical Subsystems through the Primate Amygdala

The prefrontal and insula cortex, amygdala, and striatum are key regions for emotional processing, yet the amygdala's role as an interface between the cortex and striatum is not well understood. In the nonhuman primate (Macaque fascicularis), we analyzed a collection of bidirectional tracer injections in the amygdala to understand how cortical inputs and striatal outputs are organized to form integrated cortico–amygdala–striatal circuits. Overall, diverse prefrontal and insular cortical regions projected to the basal and accessory basal nuclei of the amygdala. In turn, these amygdala regions projected to widespread striatal domains extending well beyond the classic ventral striatum. Analysis of the cases in aggregate revealed a topographic colocalization of cortical inputs and striatal outputs in the amygdala that was additionally distinguished by cortical cytoarchitecture. Specifically, the degree of cortical laminar differentiation of the cortical inputs predicted amygdalostriatal targets, and distinguished three main cortico–amygdala–striatal circuits. These three circuits were categorized as “primitive,” “intermediate,” and “developed,” respectively, to emphasize the relative phylogenetic and ontogenetic features of the cortical inputs. Within the amygdala, these circuits appeared arranged in a pyramidal-like fashion, with the primitive circuit found in all examined subregions, and subsequent circuits hierarchically layered in discrete amygdala subregions. This arrangement suggests a stepwise integration of the functions of these circuits across amygdala subregions, providing a potential mechanism through which internal emotional states are managed with external social and sensory information toward emotionally informed complex behaviors.
Anti‐tumor necrosis factor and postoperative complications in Crohn's disease: systematic review and meta‐analysis

Background: Anti‐tumor necrosis factor (TNF) antibodies are efficacious in patients with Crohn's disease (CD) but the influence of these medications on surgical outcomes in CD patients has been frequently debated. The aim was to evaluate the impact of preoperative treatment with anti‐TNF antibodies on postoperative complications in CD patients undergoing abdominal surgery. Methods: A systematic review and meta‐analysis of comparative cohort studies was performed assessing postoperative complication rates in CD patients who were treated with anti‐TNF antibodies within 3 months before surgery versus patients who were not. The primary outcome was overall complication rate within 1 month of surgery. Secondary outcomes included the rate of infectious and noninfectious complications. The quality of studies was assessed based on selection of patients and controls, comparability of the study groups, and assessment of outcomes. Odds ratios (OR) with 95% confidence intervals (CIs) were computed. Results: A total of eight studies including 1641 patients were included in our meta‐analysis. Preoperative infliximab therapy in CD patients undergoing abdominal surgery was associated with a trend toward an increased rate of total complications (OR 1.72, 95% CI, 0.93–3.19). Anti‐TNF treatments were associated with a modestly increased risk of infectious complications (OR 1.50, 95% CI 1.08–2.08), mostly remote from the surgical site (OR 2.07 95% CI 1.30–3.30) and with a trend toward a higher rate of noninfectious complications (OR 2.00, 95% CI 0.89–4.46). Conclusion: Preoperative infliximab treatment is associated with an increased risk of postoperative infectious complications, mostly nonlocal. A trend toward an increased risk of noninfectious and overall complications was also observed. (Inflamm Bowel Dis 2012;)
High-speed automated discrete blood sampling for positron emission tomography.

A computer controlled blood sampling system was designed specifically for rapid blood sampling for quantitative PET studies and uses solenoids that pinch silastic tubing, a roller pump and an inexpensive fraction collector. The controlling computer is an Apple II plus. The maximum sampling rate is one sample per 2 sec. Typical sample size is 0.90 +/- 0.02 g s.d. The loss of blood per sample is 2.6 ml. Tubing dead space is 1.2 ml. The response to a step change in activity between samples is 91% of the expected activity during high-speed sampling and 99% in the slower sampling mode. The major advantage of this device over flow-through detectors is that the blood is available for further processing to measure plasma or metabolite activities. This device has become a useful tool for quantitative PET studies, resulting in reliable sampling, lower radiation dose to personnel and fewer personnel necessary to conduct a study.
Data Mining in Personal Email Management

E-mail is still a popular mode of Internet communication and contains a large percentage of every-day information. Hence, email overload has grown over the past years becoming a problem for personal information management for users and a financial issue for companies. This survey reviews research on how a Machine Learning and Data Mining technique, such as classification, clustering can contribute to the solution to the problem by constructing intelligent techniques which automate email managing tasks. This survey contains annotations of research publications describing approaches used to aid in better understanding of the research for personal email information management. Some email mining applications such as automatic folder creation, mail summarization, automatic answering and spam filtering will be also presented.
A Novel Clustering-Based Season Factor Approach for Broiler Breeding

Season factor plays an important part in broiler breeding, but it is hard to measure. This paper presents a new approach to season factor, based on two observations. First, it is easier to find that broiler grows slow when the air temperature is too high. Second, along with the increasing of day age, the weight of broiler increase, but the weight gained seems uncertain, especially for different season. Motivated by these observations, we propose a novel clustering-based season factor approach in broiler breeding. First, we cluster four breeding seasons according to the local ten-day mean air temperature, which can catch the demarcation point of two coterminous seasons. We leverage a clustering algorithm based on the most well-known partitioning method, K-Means algorithm, to the above clustering task. Second, we analyze the seasonal broiler growth curve using trimmed mean. We use the broiler growth dataset of the most famous poultry raising company in China to evaluate our approach and the results show the effectiveness of our approach. In broiler breeding, season factor plays an important part, but it is hard to measure. This paper presents a new approach to season factor, based on two observations. First, it is easier to find that broiler grows slow when the air temperature is too high. Second, along with the increasing of day age, the weight of broiler increase, but the weight gained seems uncertain, especially for different season. Motivated by these observations, we propose a novel clustering-based season factor approach in broiler breeding. First, we cluster four breeding seasons according to the local ten-day mean air temperature, which can catch the demarcation point of two coterminous seasons. We leverage a clustering algorithm based on the most well-known partitioning method, K-Means algorithm, to the above clustering task. Second, we analyze the seasonal broiler growth curve using trimmed mean, which is less susceptible to the effects of extreme scores. Moreover, we use the broiler growth dataset of the most famous poultry raising company in China to evaluate our approach and the results show the effectiveness of our approach.
Unidirectionally aligned line patterns driven by entropic effects on faceted surfaces

A simple, versatile approach to the directed self-assembly of block copolymers into a macroscopic array of unidirectionally aligned cylindrical microdomains on reconstructed faceted single crystal surfaces or on flexible, inexpensive polymeric replicas was discovered. High fidelity transfer of the line pattern generated from the microdomains to a master mold is also shown. A single-grained line patterns over arbitrarily large surface areas without the use of top-down techniques is demonstrated, which has an order parameter typically in excess of 0.97 and a slope error of 1.1 deg. This degree of perfection, produced in a short time period, has yet to be achieved by any other methods. The exceptional alignment arises from entropic penalties of chain packing in the facets coupled with the bending modulus of the cylindrical microdomains. This is shown, theoretically, to be the lowest energy state. The atomic crystalline ordering of the substrate is transferred, over multiple length scales, to the block copolymer microdomains, opening avenues to large-scale roll-to-roll type and nanoimprint processing of perfectly patterned surfaces and as templates and scaffolds for magnetic storage media, polarizing devices, and nanowire arrays.
Antiproliferative action of dopamine and norepinephrine in neuroblastoma cells expressing the human dopamine transporter

The classical catecholamine transmitters dopamine and norepinephrine are also involved in neurodevelopment and neuron cell death. These effects are thought to be mediated by receptors coupled to intracellular second messengers and by oxidative stress, respectively. Using human SK‐N‐MC neuroblastoma cells stably transfected with the dopamine or norepinephrine transporter, we show that catecholamines have profound effects on cell viability not mediated by any of the above mechanisms. Low micromolar concentrations of dopamine or norepinephrine (1–10 μM) affected cell growth depending on the expression level of plasmalemmal transport. The growth inhibition was accompanied by a profound effect on the cell cycle profile with an arrest in G1 as determined by flow cytometry measuring DNA content. In a proportion of cells, apoptosis was present. Various antioxidants did not prevent the catecholamine effect, and there was no indication of accumulation of reactive oxygen species (as determined by hydroethidine, dichlorofluorescein, and the inactivation‐reactivation pattern of aconitase), ruling out involvement of oxidative stress. Reversal by FeCl3 and parallel effects of the iron‐chelator deferoxamine suggest that the catecholamine action was related to intracellular iron chelation. This novel biological action of dopamine and norepinephrine unrelated to neurotransmitter receptors, second messengers, or oxidative stress may be important for cell differentiation during neurodevelopment and survival of differentiated neurons.