Miracle-dz/UniFAR-FTUs huggingface dataset:
Improved space-vector modulation technique for common mode currents reduction

Modified space-vector modulations (MSVMs) that reduce the variations of common mode voltage (CMV) for decreasing common mode currents (CMCs) are a low cost interesting approach. Unfortunately the lack of full utilisation of the DC bus voltage is a severe drawback that can limit the exploitation of such modulation techniques, unless special overmodulation methods are adopted. In this study, some solutions are presented that make a trade-off between the DC bus voltage exploitation and CMCs reduction and make MSVMs appealing to most electrical drives on the market. Furthermore, the influence of dead time in CMV generation is considered thus modifying the switching patterns according to the sign of the load currents. Experimental results are presented in order to confirm the feasibility of the proposed approach.
A Survey on a System to Maintain the Storage of Contentious Image in the form of Descriptor

Child pornography is one of the rapidly increasing illegal activities in all over the world. Possession and distribution of Child pornography are considered as crimes which are prosecuted in most countries around the world. This law is so strict that it is not only just applicable to regular citizens but also to polices forces which may complicates them in gathering and sequencing evidence for future reference. Due to this problem, this module presents an innovative solution. This paper presents tools for sequencing metadata of the evidence material and also provide fast and accurate search to recover such evidence from suspect's file system which would helpful in capturing offenders and provide protection to victims . Since the widespread use of the Internet, the distribution and acquisition of child pornography, namely illegal and immoral images and video files of children, or "any visual depiction of illegally explicit conduct involving children has dramatically increased. Nowadays, the exchange of information between people is mainly through the World Wide Web (WWW), the peer-to peer networks, e-mail, and instant messaging services. Thus the analysis of computer storage media such as hard disk drives, pen drives, optical media and memory card is very much important to verify the presence and distribution of child pornography. Possession of illegal images is considered as a crime and this law is not applicable to only regular citizens but also to the police unit. Police officers have to destroy all the evidence after the investigation is completed which may complicate them in gathering and presenting evidence in investigation. Due to this is impossible for police forces to make connection between individual cases in order to find evidence in suspect's system. To overcome this problem, this paper presents an application or tool which is able to catalogue the image of child pornography. In the proposed system, during investigation police officers can extract the metadata from suspected system and store it in the form of descriptor in the SEQUENCER component. When they have access to the suspect's system they can use SEARCHER component to find identical data or very visually similar to the samples present in the database. This application is consist of two components. Most of the application has already demonstrated such as generic MIRROR (12) content-based image retrieval system and more specific system such as GAMA, designed for accessing libraries of media art. With this, there are again more applications such as EnCase and Forensic Tool Kit (FTK) which determine the relationship in the data and find key parts of information and generate reports that are easily consumed by other investigator. The above mentioned tools allows only the retrieval of images that are identical (they utilize MD5 sums), and also allows the retrieval of similar images, since it utilizes MPEG-7 descriptor values.
Retention of the NLRP3 Inflammasome–Primed Neutrophils in the Bone Marrow Is Essential for Myocardial Infarction–Induced Granulopoiesis

Supplemental Digital Content is available in the text. Background: Acute myocardial infarction (MI) results in overzealous production and infiltration of neutrophils to the ischemic heart. This is mediated in part by granulopoiesis induced by the S100A8/A9-NLRP3-IL-1β signaling axis in injury-exposed neutrophils. Despite the transcriptional upregulation of the NLRP3 (Nod Like Receptor Family Pyrin Domain-Containing 3) inflammasome and associated signaling components in neutrophils, the serum levels of IL-1β (interleukin-1β), the effector molecule in granulopoiesis, were not affected by MI, suggesting that IL-1β is not released systemically. We hypothesize that IL-1β is released locally within the bone marrow (BM) by inflammasome-primed and reverse-migrating neutrophils. Methods: Using a combination of time-dependent parabiosis and flow cytometry techniques, we first characterized the migration patterns of different blood cell types across the parabiotic barrier. We next induced MI in parabiotic mice by permanent ligation of the left anterior descending artery and examined the ability of injury-exposed neutrophils to permeate the parabiotic barrier and induce granulopoiesis in noninfarcted parabionts. Last, using multiple neutrophil adoptive and BM transplant studies, we studied the molecular mechanisms that govern reverse migration and retention of the primed neutrophils, IL-1β secretion, and granulopoiesis. Cardiac function was assessed by echocardiography. Results: MI promoted greater accumulation of the inflammasome-primed neutrophils in the BM. Introducing a time-dependent parabiotic barrier to the free movement of neutrophils inhibited their ability to stimulate granulopoiesis in the noninfarcted parabionts. Previous priming of the NLRP3 inflammasome is not a prerequisite, but the presence of a functional CXCR4 (C-X-C-motif chemokine receptor 4) on the primed-neutrophils and elevated serum S100A8/A9 levels are necessary for homing and retention of the reverse-migrating neutrophils. In the BM, the primed-neutrophils secrete IL-1β through formation of gasdermin D pores and promote granulopoiesis. Pharmacological and genetic strategies aimed at the inhibition of neutrophil homing or release of IL-1β in the BM markedly suppressed MI-induced granulopoiesis and improved cardiac function. Conclusions: Our data reveal a new paradigm of how circulatory cells establish a direct communication between organs by delivering signaling molecules (eg, IL-1β) directly at the sites of action rather through systemic release. We suggest that this pathway may exist to limit the off-target effects of systemic IL-1β release.
The transformerless ac-dc and dc-dc converters with a diode-capacitor voltage multiplier

This paper presents a transformerless ac-dc and or dc-dc converter with a high output voltage multiplicity, which contains only one switch. The converter consists of the inverter and diode-capacitor multiplier (DCM), which provides the voltage gain equal to the double number of the multiplier steps. In the case of the ac-dc conversion the proposed converter offers practically unit power factor and provides a sine wave input current. The analysis of the steady state as well as the transient behavior of the DCM is given and a simplified equivalent circuit is proposed. The prototype of the DCM has been built and tested to show the validity of the proposed converter. The theoretical analysis, the computer simulation results and the experimental testing results are in good agreement.
Fundamentals of a new diode clamping multilevel inverter

The conventional diode clamping inverter suffers from such problems as DC link unbalance, indirect clamping of the inner devices, turn-on snubbing of the inner DC rails as well as series association of the clamping diodes etc. It is due largely to these problems that the application of the conventional diode clamping inverter in practice has been deterred, in spite of the growing discussion in the literature. The paper proposes a new diode clamping inverter, which works without the series association of the clamping diodes. An auxiliary resistive clamping network solving the indirect clamping problem of the inner devices is also discussed for both the new and conventional diode clamping inverter. Operation principle, clamping mechanism, auxiliary clamping as well as experimentation are presented.
Monte Carlo simulation for the prediction of the emission level from multiple sources inside shielded enclosures

The emission level from multiple sources inside shielded enclosures is presented. Fields are expressed through the dyadic Green's function. Integrated circuits are modeled as electric and magnetic dipoles. Induced electric current magnitudes on the walls of the enclosures are analytically calculated. Probabilistic models based on measurement data for various source configurations are derived and Monte Carlo simulations are produced. The results are used for the prediction of possible emission margins. Applications in PCB design are discussed and suggestions are made.
Effects of Positive Psychology Interventions on the Well-Being of Young Children: A Systematic Literature Review

Over the last 20 years, the effectiveness of positive psychology interventions for the development of the well-being of children and adolescents and the moderation of high levels of anxiety and depression in this population has been largely demonstrated. Emphasis has been placed on the promotion of well-being and prevention of mental health problems in the school context in order to foster, through positive psychology, the cognitive and socio-emotional development of primary and secondary students, e.g., by strengthening positive relationships, positive emotions, character strengths, optimism, and hope. However, little is known about the impact of these interventions on young children. This systematic review aims at examining the effects of positive psychology interventions on the well-being of early childhood children (<6 years old), both in the preschool education context with educators or teachers and also in the family context with parents. Several electronic databases were searched, and the findings systematically reviewed and reported by the PRISMA guidelines. Very few studies met the inclusion criteria (n = 3), highlighting the need for further research in this area. Indeed, all of the selected studies demonstrated the importance of positive psychology interventions with young children to promote positive aspects of development, such as gratitude, positive emotions, life satisfaction, accomplishment, positive relationship, or self-esteem. Limitations in the field are discussed.
microRNA-27a-3p but Not -5p Is a Crucial Mediator of Human Adipogenesis

MicroRNAs (miRNAs), a class of small, non-coding RNA molecules, play an important role in the posttranscriptional regulation of gene expression, thereby influencing important cellular functions. In adipocytes, miRNAs show import regulatory features and are described to influence differentiation as well as metabolic, endocrine, and inflammatory functions. We previously identified miR-27a being upregulated under inflammatory conditions in human adipocytes and aimed to elucidate its function in adipocyte biology. Both strands of miR-27a, miR-27a-3p and -5p, were downregulated during the adipogenic differentiation of Simpson–Golabi–Behmel syndrome (SGBS) cells, human multipotent adipose-derived stem cells (hMADS), and human primary adipose-derived stromal cells (hASCs). Using miRNA-mimic transfection, we observed that miR-27a-3p is a crucial regulator of adipogenesis, while miR-27a-5p did not alter the differentiation capacity in SGBS cells. In silico screening predicted lipoprotein lipase (LPL) and peroxisome proliferator activated receptor γ (PPARγ) as potential targets of miR-27a-3p. The downregulation of both genes was verified in vitro, and the interaction of miR-27-3p with target sites in the 3′ UTRs of both genes was confirmed via a miRNA-reporter-gene assay. Here, the knockdown of LPL did not interfere with adipogenic differentiation, while PPARγ knockdown decreased adipogenesis significantly, suggesting that miR-27-3p exerts its inhibitory effect on adipogenesis by repressing PPARγ. Taken together, we identified and validated a crucial role for miR-27a-3p in human adipogenesis played by targeting the essential adipogenic transcription factor PPARγ. Though we confirmed LPL as an additional target of miR-27a-3p, it does not appear to be involved in regulating human adipogenesis. Thereby, our findings call the conclusions drawn from previous studies, which identified LPL as a crucial regulator for murine and human adipogenesis, into question.
Energy harvesting in the super-harmonic frequency region of a twin-well oscillator

Nonlinear dynamical systems exhibit super-harmonic resonances that can activate large-amplitude motions at fraction integers of the fundamental frequency of the system. Such resonances offer a unique and untapped opportunity for harnessing vibratory energy from excitation sources with low-frequency components. To that end, this paper exploits the super-harmonic frequency bands of a nonlinear twin-well (bi-stable) oscillator for harvesting energy from low-frequency excitations. Theoretical and experimental studies are performed on an axially loaded clamped-clamped piezoelectric beam harvester with bi-stable potential characteristics. Voltage- and power-frequency bifurcation maps are generated near the super-harmonic resonance of order two. It is shown that, for certain base acceleration levels, the harvester can exhibit responses that are favorable for energy harvesting. These include a unique branch of large-orbit periodic inter-well oscillations, coexisting branches of large-orbit solutions, and a bandwidth of frequencies where a unique chaotic attractor exists. In these frequency regions, the harvester can produce power levels at half its fundamental frequency that are comparable to those obtained near the fundamental frequency.
Widowhood and Health Status Among Chinese Older Adults: The Mediation Effects of Different Types of Support

Although many studies have suggested that widowhood is related to worse health conditions among older adults, few have examined the mediation effects of social support between widowhood and health. Employing mediation analysis to a sample of data from the 2014 wave of China Longitudinal Aging Social Survey (CLASS), this study examined the mediation effects of social support, including emotional support, instrumental support, and companionship, in the widowhood-health association among older adults. The results indicated that the negative effect of widowhood on older adults' health was in part attributable to decreased emotional support and companionship. Specifically, emotional support exerted a significant role in the widowhood-mental health association, and companionship exerted a significant role in widowhood-physical health and widowhood-mental health associations. In the subsample analysis, the mediation effects were only significant among female older adults, and among rural older adults. Our findings highlight the importance of emotional support and companionship in maintaining health among widowed older adults and strategies should pay more attention to female and rural widowed older adults.
Senior tourists’ motivations for visiting cultural destinations: a cluster approach

ABSTRACT This study sought to contribute to the existing knowledge of consumer psychology regarding senior tourism in cultural destinations by improving the existing understanding of seniors’ motivations and related psychological processes. The research objectives were to outline a model of senior tourists’ push and pull motivations, which includes their emotions and satisfaction in cultural destinations; to understand the selection process of tourist attractions and activities in these destinations; and to identify clusters of seniors based on their emotions and level of satisfaction during visits. A theoretical model was created to analyse motivations and travel factors. The data collected facilitated the identification of four senior tourist clusters based on sociodemographic and psychographic differences. Various theoretical and managerial implications are presented.
Exoskeleton-based robotic platform applied in biomechanical modelling of the human upper limb

One of the approaches to study the human motor system, and specifically the motor strategies implied during postural tasks of the upper limbs, is to manipulate the mechanical conditions of each joint of the upper limbs independently. At the same time, it is essential to pick up biomechanical signals and bio-potentials generated while the human motor system adapts to the new condition. The aim of this paper is two-fold: first, to describe the design, development and validation of an experimental platform designed to modify or perturb the mechanics of human movement, and simultaneously acquire, process, display and quantify bioelectric and biomechanical signals; second, to characterise the dynamics of the elbow joint during postural control. A main goal of the study was to determine the feasibility of estimating human elbow joint dynamics using EMG-data during maintained posture. In particular, the experimental robotic platform provides data to correlate electromyographic EMG activity, kinetics and kinematics information from the upper limb motion. The platform aims consists of an upper limb powered exoskeleton, an EMG acquisition module, a control unit and a software system. Important concerns of the platform such as dependability and safety were addressed in the development. The platform was evaluated with 4 subjects to identify, using system identification methods, the human joint dynamics, i.e. visco-elasticity. Results obtained in simulations and experimental phase are introduced.
Analysis of the Radial Pulse Wave and Its Clinical Applications: A Survey

The arterial pulse wave is a physiological signal which can reflect the function of the human cardiovascular system. Owing to the measurement being convenient and safe, radial pulse waves have been often used in noninvasive monitoring of human health, which can further reflect the health status of the cardiovascular system, including information of the aorta and peripheral arteries. Moreover, radial pulse waves can assist clinical diagnosis in the prevention and treatment of cardiovascular disease. This paper systematically reviews the progress in analysis of pulse wave analysis, including pulse wave acquisition, waveform processing, pattern classification, parameter estimation, and clinical applications. In terms of waveform acquisition, this paper reviews a variety of methods to obtain radial pulse waves, including tonometry, photoplethysmography, ultrasound manometry, and flexible tactile pressure sensors. In the aspect of waveform processing, this paper summarizes the methods of radial pulse waves preprocessing and feature extraction. With the rapid development of machine learning and deep learning algorithms, radial pulse waves can be used to identify the status of human cardiovascular systems and to estimate parameters related to cardiovascular function. This paper also discusses the applications of radial pulse waves in clinical practice, including cardiovascular function evaluation and pulse diagnosis in traditional Chinese medicine. Some open-source databases and analysis software are also listed. The current development trend, challenges, and future directions of analysis of radial pulse waves are also offered.
Dis/abled Student Campusmaking: Sites of New Possibility

Scholars have attempted to reveal the structural barriers that dis/abled students cope with and navigate during college, but it remains unclear how these students interpret their experiences on campus and what strategies they employ to manage and respond to unsupportive and hostile campus climates. In this paper, we describe freedom movements that sought to secure equal access to opportunities and rights for people with dis/abilities, and we highlight and explain forms of resistance among d/Deaf and dis/abled postsecondary students. To do so, we draw on dis/ability critical race theory and also advance the concept of campusmaking, which refers to the ways that students navigate complex campus spaces and create sites of togetherness and resistance. We discuss broader structural and climate issues facing college students with dis/abilities, particularly those who are Black, Indigenous, and people of color. In so doing, we gain insight into dis/abled student campusmaking amid and in spite of ableist and racist postsecondary contexts. We conclude with a discussion of the gaps in existing research and the questions that warrant further study.
Experimental investigations on thermal and hydrodynamic entrance regionis in microchannels using oPIV and TLC techniques

Micro-systems are expected to have abundant applicability in the biomedical industry, where operations such as medical diagnostics or DNA synthesis and sequencing, could potentially be carried out on a hand-held device. Fully integrated micro-systems consist of several processes needed to carry out the analysis, such as mixing, reaction, and detection. These systems are projected to have significant advantages over traditional testing methods, such as smaller footprint areas, portability, and shorter analysis times. Micro-systems are comprised of micro-devices, which perform the desired processes. Micro-devices themselves, such as micromixers or micro-heat exchangers, are an arrangement of microchannels, which span only a fraction of a millimeter. Consequently, microchannels have recently received much attention in the research community. Essential for advanced design applications are flow and heat transfer analyses of microchannels, which are used to transport fluid within micro-systems and their integrated components. The entrance region of a channel, where the flow is hydrodynamically, thermally, or simultaneously developing, is very important since the flow and heat transfer mechanisms are enhanced due to the developing nature of the flow. Through the use of state-of-the-art optical measurement techniques of micro-Particle Image Velocimetry (oPIV) and un-encapsulated Thermochromic Liquid Crystal (TLC) thermography, the hydrodynamic and thermal entrance regions in microchannels are experimentally investigated. New experimental data is obtained for both laminar and turbulent single-phase flow regimes, in microchannels ranging in hydraulic diameter from 100 om to 1 mm. To investigate the effects of dimensional scaling, the results are compared to the physical mechanisms, observations, and existing data for developing flows in conventionally-sized ducts and pipes. In addition, new empirical laminar entrance length correlations are proposed for microchannels. In microfluidic devices and systems, channel lengths are expected to be extremely short, in which case developing flow may dominate the flow field over the entire microchannel length. The present study broadens the knowledge into the mechanisms of developing flow and heat transfer in microchannels. With further understanding of micro flows through experimental evidence, the applicability of complete microfluidic systems can be realized on a practical level