Miracle-dz/UniFAR-FTUs huggingface dataset:
Hierarchical Identity-Based Proxy Re-Encryption without Random Oracles

In a proxy re-encryption scheme, a semi-trusted proxy converts a ciphertext for Alice into a ciphertext for Bob without seeing the underlying plaintext. A number of solutions have been proposed in public key settings. Hierarchical identity-based cryptography is a generalization of identity-based encryption that mirrors an organizational hierarchy, which allows a root private key generator to distribute the workload by delegating private key generation and identity authentication to lower-level private key generators. In this paper, we propose a hierarchical identity-based proxy re-encryption (HIBPRE) scheme which achieves IND-PrID-CCA2 security without random oracles. This is the first HIBPRE scheme up to now, and our scheme satisfies unidirectionality, non-interactivity and permits multiple re-encryptions.
Detection of Denial-of-service Attacks

Denial-of-service (DOS) is a type of computer attack, which can essentially disable computers and networks. Resource consumption type of DOS attack could not be detected by the traditional misuse detection technique. This paper presents a new method of support vector mchine (SVM) to detect these attacks. We find that a DOS attack to a host is related to the activities within an impact data set of the host. The SVM method is used to classify the subsets of an impact data set to estimate its anomalism. The experiment result shows that this method can detect resource consumption type of DOS attacks, such as SYN-flood, Smurf and UDP-storm. A receiver operating characteristic curve is plotted to determine performance for any possible operating point of the DOS attacks detection.
Isolation and characterization of polymorphic microsatellite loci in the green leafhopper Empoasca vitis Goethe (Homoptera)

Eight dinucleotide microsatellite loci were isolated and characterized within the green leafhopper Empoasca vitis (Goethe) using an enrichment cloning procedure. Primers were tested on 171 individuals collected in the southwest of France from the vine plants. The identified loci were polymorphic, with allelic diversity ranging from two to 18 alleles per locus. Observed heterozygosities were from 0.021 to 0.760. These microsatellite markers should prove to be a useful tool for estimating the population genetic structure, host‐plant specialization and migration capacity of this insect.
The Health-Related Quality of Life of Children With an Extremity Fracture: A One-Year Follow-up Study

Purpose: To document the health-related quality of life (HRQOL) of children with an extremity fracture at 3 and 12 months postinjury and to determine whether it varies significantly by fracture region and site. Methods: Children hospitalized for an extremity fracture at 4 pediatric trauma centers were studied. A baseline, 3-month, and 12-month telephone interview were completed by a primary caregiver to measure the child's HRQOL using the Pediatric Quality of Life Inventory (PedsQL). HRQOL was modeled as a function of injury, patient, and family characteristics using a longitudinal regression model. Result: Of the 100 children enrolled, 52 sustained a lower extremity fracture (LEF) and 48 an upper extremity fracture (UEF). Postinjury HRQOL scores were significantly poorer than preinjury scores for all subjects (P = 0.05). In addition, a significant proportion of subjects reported impaired physical and psychosocial HRQOL at 3 (44% and 46%, respectively) and 12 months (23% and 33%, respectively) postinjury. At 3 months postinjury, children with an LEF had significantly poorer HRQOL outcomes compared to children with a UEF. By 12 months postinjury, the physical function of children with a tibia and/or fibula fracture remained significantly lower than children with a UEF (P ≤ 0.05). Conclusions: Children hospitalized for an extremity fracture suffered dramatic declines in physical and psychosocial well-being during the first 3 months postinjury. By 1 year postinjury, most children recovered; however, children with a tibia and/or fibula fracture still reported significantly poorer physical functioning.
Formation of electrostatic interactions on the protein-folding pathway.

We describe a novel method of obtaining information about the structures of transient conformations on the folding pathway from their ionization equilibria: the H+ -titration behavior of a protein residue is determined in detail by its environment. We follow the consolidation of electrostatic interactions in the folding process by comparing the acid-titration behavior of four conformations on the folding pathway of barnase: the denatured state (D); the folding intermediate (I); the major transition state(+); and the native state (N) in the scheme D <==>I<==>(+)<==)N. The results show that strong electrostatic interactions are present in the major transition state: some of its carboxylate groups display the highly anomalous pKA values of <2 that are found in N. However, the network of ionic surface interactions is not formed in (+), and the overall protection of titrating residues is weakened. The results are consistent with the transition state being an expanded form of the native state, with a weakened but poorly hydrated core and a loosened periphery. The surface residues in such an expanded conformation are, on average, farther apart than are those in the center of the molecule. The results concerning the folding intermediate are less clear cut. We show that the interpretation of kinetic data relating to folding intermediates depends critically on assumptions about their equilibrium with other denatured states. We have, however, characterized the pH and ionic strength dependence of an apparent stability of I, using the deviation from two-state folding behavior, which can be used to investigate electrostatic properties of folding intermediates from a variety of mechanisms. In general, the data imply that I is somewhat similar to (+). Apparently odd titration properties of I are investigated further in the accompanying paper [Oliveberg, M. , & Fersht, A. (1996) Biochemistry 35, 2738-2749]. The approach in this study may be of particular use in testing theoretical results since the relationship between H+ -titration properties and protein structure can be treated by classical electrostatics.
Tinnitus after Simultaneous and Sequential Bilateral Cochlear Implantation

Importance There is an ongoing global discussion on whether or not bilateral cochlear implantation should be standard care for bilateral deafness. Contrary to unilateral cochlear implantation, however, little is known about the effect of bilateral cochlear implantation on tinnitus. Objective To investigate tinnitus outcomes 1 year after bilateral cochlear implantation. Secondarily, to compare tinnitus outcomes between simultaneous and sequential bilateral cochlear implantation and to investigate long-term follow-up (3 years). Study design This study is a secondary analysis as part of a multicenter randomized controlled trial. Methods Thirty-eight postlingually deafened adults were included in the original trial, in which the presence of tinnitus was not an inclusion criterion. All participants received cochlear implants (CIs) because of profound hearing loss. Nineteen participants received bilateral CIs simultaneously and 19 participants received bilateral CIs sequentially with an inter-implant interval of 2 years. The prevalence and severity of tinnitus before and after simultaneous and sequential bilateral cochlear implantation were measured preoperatively and each year after implantation with the Tinnitus Handicap Inventory (THI) and Tinnitus Questionnaire (TQ). Results The prevalence of preoperative tinnitus was 42% (16/38). One year after bilateral implantation, there was a median difference of −8 (inter-quartile range (IQR): −28 to 4) in THI score and −9 (IQR: −17 to −9) in TQ score in the participants with preoperative tinnitus. Induction of tinnitus occurred in five participants, all in the simultaneous group, in the year after bilateral implantation. Although the preoperative and also the postoperative median THI and TQ scores were higher in the simultaneous group, the median difference scores were equal in both groups. In the simultaneous group, tinnitus scores fluctuated in the 3 years after implantation. In the sequential group, four patients had an additional benefit of the second CI: a total suppression of tinnitus compared with their unilateral situation. Conclusion While bilateral cochlear implantation can have a positive effect on preoperative tinnitus complaints, the induction of (temporary or permanent) tinnitus was also reported. Clinical Trial Registration Dutch Trial Register NTR1722.
Caching and Scheduling Mechanisms for H.264 Video Flow Delivery over Discontinuous Coverage Wireless Networks

The past few years have witnessed the deployment of a wide variety of multimedia applications over wireless networks. As a consequence, mobile users are demanding fast and efficient connectivity, especially concerning start-up delays and flow quality. Wireless networks aim at providing an everywhere coverage without spending prohibitive deployment costs. Thus, the coverage of each access point is extended with detriment to the mean throughput of the radio cell. The coverage is continuous, but radio conditions met by users are not homogeneous. Actually, data rate is varying according to user mobility. In the context of streaming applications, intermittent high rate availability may lead to service disruption, especially when user's number increases. Thus, it is essential to design a network architecture able to efficiently deliver video flows to mobile users. In our works, a new equipment, called network cache, is introduced. The latter performs efficient flow caching and scheduling, in order to guarantee service continuity. The simulation shows that the proposed architecture gives satisfying service start-up delays and improves system scalability.
In vitro evaluation of the antibacterial activity of Arctium lappa as a phytotherapeutic agent used in intracanal dressings

The discovery of natural biocomponents from plants with antibacterial activity on endodontic microbiota may lead to new therapies. This study evaluated the antibacterial activity of a phytotherapeutic agent prepared from an ethyl acetate fraction (AcOEt) extracted from Arctium lappa. This agent was compared with calcium hydroxide as an intracanal dressing. Twenty‐seven maxillary canines were instrumented, sterilized and inoculated with a mixed bacterial suspension of Pseudomonas aeruginosa, Escherichia coli, Lactobacillus acidophilus, Streptococcus mutans and Candida albicans. The teeth were divided into three groups and their canals filled with: group 1, calcium hydroxide and propylene glycol; group 2, a paste containing AcOEt fraction of A. lappa and propylene glycol; group 3, propylene glycol (control). At 7, 14 and 30 days, three teeth from each group were opened and a paper point was placed in the root canal for 5 min. The paper points were transferred to Petri dishes with Brain Heart Infusion (BHI). The bacterial growth was classified. Mild bacterial growth was found in group 1 at all time intervals; in group 2 there was severe growth at 7 days, but no growth at 14 and 30 days. The phytotherapeutic agent extracted from an AcOEt fraction of A. lappa inhibited the growth of all the microorganisms in this study. Copyright © 2006 John Wiley & Sons, Ltd.
Similarities between the spectrin SH3 domain denatured state and its folding transition state.

We have expanded our description of the energy landscape for folding of the SH3 domain of chicken alpha-spectrin by a detailed structural characterization of its denatured state ensemble (DSE). This DSE is significantly populated under mildly acidic conditions in equilibrium with the folded state. Evidence from heteronuclear nuclear magnetic resonance (NMR) experiments on (2)H, (15)N-labeled protein suggests the presence of conformers whose residual structure bears some resemblence to the structure of the folding transition state of this protein. NMR analysis in a mutant with an engineered, non-native alpha-helical tendency shows a significant amount of local non-native structure in the mutant, while the overall characteristics of the DSE are unchanged. Comparison with recent theoretical predictions of SH3 domain folding reactions reveals an interesting correlation with the predicted early events. Based on these results and recent data from other systems, we propose that the DSE of a protein will resemble the intermediate or transition state of its nearest rate-limiting step, as a consequence of simple energetic and kinetic principles.
Fault tolerant control for a general class of nonholonomic dynamic systems via terminal sliding mode

In this paper, a constructive fault tolerant control strategy is developed for a general class of uncertain non-holonomic systems. The terminal slide mode technique and the minimal dilation degree scheme are used to accommodate the actuator partial loss of effectiveness and additive actuation fault. Two step control procedures are proposed under the finite time convergence. The parking problem for a wheeled mobile robot is presented to illustrate the effectiveness of the fault tolerant control strategy and demonstrate the application of the general system.
Supplemental Data Sanguinarine , Putative Anticancer Therapeutic , Interacts with Chromatin , Modulates Epigenetic Modifications and Transcription in Context of Chromatin

Preparation of Chromatin and Mononucleosome from Rat Liver Purified nuclei were digested with micrococcal nuclease for the preparation of chromatin. Prolonged digestion of the nuclei with micrococcal nuclease was used to prepare mononucleosome with a DNA length of 146 base pairs. Selective solubilization of mononucleosome was done by the acidification (NaH2PO4 1.78% w/v) of the supernatant. The supernatant thus obtained was dialyzed against 0.01M Tris-HCl, pH 7.5, containing 0.01M EDTA and 0.002M PMSF. Final purification of mononucleosome was achieved by gel filtration using 25 cm x 1 cm sephacryl S-200 column. Purity of the chromatin and mononucleosome was checked by identification of histones in SDS-PAGE with commercially available sample of histones. The purity of the nucleosomal DNA was checked by agarose gel electrophoresis with appropriate markers. Concentrations of chromatin and mononucleosome are expressed in terms of DNA base. Chromosomal DNA was extracted from the chromatin by repeated phenol/chloroform for quantitative estimation of base.
Novel acceleration methods for electromagnetic modeling of high-speed interconnects in distribution grids ASIC

Application Specific Integrated Circuits (ASICs) serving as the hardware foundation of smart equipment, play an important role in operation, control, protection and communication of future distribution grids. Recently, the design and electromagnetic (EM) analysis of high-speed interconnects is the key part for Integrated Circuit (IC) technology, especially for ASICs. The full wave spectral domain approach (SDA) in conjunction with Method of Moment (MoM) is the most accurate and comprehensive approach among all EM modeling approach of high-speed interconnects. However, acceleration methods are needed to decrease its complexity and increase its efficiency. Novel acceleration methods in SDA are present to solve a typical high-speed interconnect structure. Numerical results show that the novel methods can achieve higher accuracy and efficiency than conventional acceleration methods.
Synaptic scaffolding molecule interacts with Axin

Synaptic scaffolding molecule (S‐SCAM) is a synaptic protein that consists of PDZ domains, a guanylate kinase domain, and WW domains. It interacts with N‐methyl‐d‐aspartate receptor subunits, neuroligin, and β‐catenin. Here, we identified Axin as a novel binding partner of S‐SCAM. Axin was co‐immunoprecipitated with S‐SCAM from rat brain, detected in the post‐synaptic density fraction in rat brain subcellular fractionation, and partially co‐localized with S‐SCAM in neurons. The guanylate kinase domain of S‐SCAM directly bound to the GSK3β‐binding region of Axin. S‐SCAM formed a complex with β‐catenin and Axin, but competed with GSK3β for Axin‐binding. Thereby, S‐SCAM inhibited the Axin‐mediated phosphorylation of β‐catenin by GSK3β.
Purification and characterization of the extracellular alpha-amylase from Clostridium acetobutylicum ATCC 824

The extracellular alpha-amylase (1,4-alpha-D-glucanglucanohydrolase; EC 3.2.1.1) from Clostridium acetobutylicum ATCC 824 was purified to homogeneity by anion-exchange chromatography (mono Q) and gel filtration (Superose 12). The enzyme had an isoelectric point of 4.7 and a molecular weight of 84,000, as estimated by sodium dodecyl sulfate-polyacrylamide gel electrophoresis. It was a monomeric protein, the 19-amino-acid N terminus of which displayed 42% homology with the Bacillus subtilis saccharifying alpha-amylase. The amino acid composition of the enzyme showed a high number of acidic and hydrophobic residues and only one cysteine residue per mole. The activity of the alpha-amylase was not stimulated by calcium ions (or other metal ions) or inhibited by EDTA, although the enzyme contained seven calcium atoms per molecule. alpha-Amylase activity on soluble starch was optimal at pH 5.6 and 45 degrees C. The alpha-amylase was stable at an acidic pH but very sensitive to thermal inactivation. It hydrolyzed soluble starch, with a Km of 3.6 g . liter-1 and a Kcat of 122 mol of reducing sugars . s-1 . mol-1. The alpha-amylase showed greater activity with high-molecular-weight substrates than with low-molecular-weight maltooligosaccharides, hydrolyzed glycogen and pullulan slowly, but did not hydrolyze dextran or cyclodextrins. The major end products of maltohexaose degradation were glucose, maltose, and maltotriose; maltotetraose and maltopentaose were formed as intermediate products. Twenty seven percent of the glucoamylase activity generally detected in the culture supernatant of C. acetobutylicum can be attributed to the alpha-amylase.
Effect of repeated application of pendimethalin on its persistence and dissipation kinetics in soil under field and laboratory conditions

ABSTRACT The repeated application of herbicide can alter its persistence in the environment. In India, wheat fields are exposed to herbicide application at least once in the cropping season. The present study investigated the dissipation behavior of pendimethalin applied annually to a wheat field over four cropping seasons from 2012 to 2016. The dissipation studies were also conducted under laboratory conditions during 2015–2016. Pendimethalin from soil and wheat grain samples was extracted using matrix solid-phase dispersion and quantified using high-performance liquid chromatography and gas chromatography–tandem mass spectrometry. The average recoveries of pendimethalin from soil and crop produce ranged from 81.3% to 103.1%. The half-life of pendimethalin ranged from 20.9 to 31.3 days and 9.4 to 60.2 days under field and laboratory conditions, respectively. Dissipation of pendimethalin varied significantly over the years under field conditions and was comparatively faster than under laboratory conditions. On the other hand, non-significant variation in the dissipation of pendimethalin in soils under laboratory conditions was observed. The residues of pendimethalin in crop produce at harvest were below the maximum residue limit set by EPA.
Identification of Languages and Encodings in a Multilingual Document

Text on the Web is available in numerous languages and encodings, often not according to any standards. The number of multilingual documents on the Web is also increasing. The problem of identifying the languages and encodings in a multilingual document and marking portions of a document with them has not been addressed so far. We present an exploration of this problem, the implied or required assumptions, and a solution. The problem can be divided into three parts: monolingual identification, enumeration of languages and identification of the language of every portion. For enumeration, we have been able to get a precision of 96.20%. We also experimented on language identification of each word. Given correct enumeration, we could obtain type precision of 90.91% and token precision of 86.80%. Finally, we show how precision is affected by language distance.
Frontal lobes and older sex offenders: a preliminary investigation

Since the 1930s, researchers have speculated on the causes of sexual offending in older men (Henninger, 1939). Although official statistics indicate that men over 60 years commit about 10% of recorded sexual crimes in England and Wales (Fazel and Jacoby, 2002), little research has been conducted to investigate risk factors for sexual deviancy in this group. It has been hypothesized that older men sustain agerelated brain changes that may precipitate such offending behaviour (Roth, 1968). In support, retrospective examination of psychiatric diagnoses of older offenders referred by court for psychiatric assessment found an association between dementia and being charged with a sexual offence (Fazel and Grann, 2002). Evidence from studies in individuals displaying antisocial behaviour has demonstrated that changes in the frontal lobe are an important area to investigate (Anderson et al., 1999; Raine et al., 2000). For example, a recent study comparing personality profiles and neuropsychological test scores of violent offenders, arson offenders and sex offenders found poorer perseverative error scores on the Wisconsin Card Sorting Test in arsonists, although overall
Harpsipani : A Replicated User-Level Filesystem

This paper describes the design and implementation of Harpsipani, a replicated, highly-available distributed filesystem. Harpsipani is built entirely in Go and uses the replicated state machine approach to provide high availability and durability of filesystem data and metadata. It maintains a centralized log to be able to respond to clients without waiting for the operation to be applied at every replica machine. We show that Harpsipani is functional in practice, despite adding significant overhead.
Developing the Automatic Control System Based on Neural Controller

Mostly the dynamics of controlled objects is often described by nonlinear equalizations. Last years themethodology of neural networks is engaged into designing the systems controlling such objects, in particular due to theinfluence of nonlinearities can be taken into account by nonlinear functions of the activation. Such methodology brings someintelligence to the designed system.Authors proposed the purposeful procedure of forming the structure of the neural controller according the desired lawof the control using the discrete transformation of the motion equation. Requirements to the mathematical model of thereference and method of network training are determined, and the control quality is estimated at traditional passing thedisagreement error in the controller input and for the proposed new configuration of its input circuit, namely with separatedinputs. Simulation results confirmed providing the better quality of the system control. DOI: http://dx.doi. org/10.5755/j01.itc. 44.3. 7717
Modelling approaches for predictive control of large-scale sewage systems

In this report, model predictive control (MPC) of large-scale sewage systems is addressed considering different modelling approaches that include several inherent continuous/discrete phenomena (overflows in sewers and tanks) and elements (weirs) in the system that result in distinct behaviour depending on the dynamic state ( flow/volume) of the network. These behaviours can not be neglected nor can be modelled by a pure linear representation. In order the MPC controller takes into account these phenomena and elements, a modelling approach based on piece-wise linear functions is proposed and compared against a hybrid modelling approach previously reported by the authors. Control performance results and associated computation times of the closed-loop scheme considering both modelling approaches are compared by using a real case study based on the Barcelona sewer network.