Miracle-dz/UniFAR-FTUs huggingface dataset:
Effectiveness of Co-inoculation with Pseudomonas koreensis and Rhizobia on Growth, Nodulation and Yield of Common Bean (Phaseolus vulgaris L.)

The establishment of nodulation, nitrogen fixation and productivity in legumes is affected by specificity of inoculant’s strain and effectiveness as well as interactions with rhizosphere El-Nahrawy and 21(6): 1-15, 3612), T 3 = Inoculation with P. koreensis, and T 4 = T 2 +T 3 with 5 replicates. Co-inoculation treatment significantly enhanced plant height, nodulation, dry biomass and increased macroelements content (N, P and K) and microelements content (Zn, Mn, Fe and Cu) over single inoculation and control at 30 and 60 days of sowing. The treatments T 4 and T 3 recorded the highest values at all growth stages, they recorded 241.00 and 225.66 μg TPF g -1 soil day -1 at 30 days and 249.33 and 235.00 μg TPF g -1 soil day -1 at 60 days and 203.66 and 179.66 μg TPF g -1 soil day -1 at harvest for dehydrogenase activity. Also, phosphatase activity in soil generally reduced with the aging of the plant. Similar trend are showed for seed yield and quality assessment. Therefore, co-inoculation with R. leguminosarium sembiovar phaseoli and P. koreensis could be an effective biofertilization for common bean plant production.
The Effect on Portfolio Performance of Diversification into Socially Responsible Investments: Evidence from an Australian context

Socially responsible investment (SRI) has grown significantly in the last ten years. Many international organizations have become increasingly involved in the movement towards SRI. The move towards SRI investing is being driven by institutions such as the United Nations Principles for Responsible Investing whose membership of financial institutions, including asset owners and institutional investors, holds assets totalling US$13 trillion. This growth was promoted further by the 2006 launch of the Principles for Responsible Investment (PRI), with an agreement by leading pension funds, asset managers and consultants to develop new strategies to embed environmental, social and governance issues (ESG-issues). The tremendous growth has caught the attention of investors and fund managers that are seeking alternative assets and markets to improve their portfolio performance. There are claims, based on recent evidence, that SRI can provide investors’ portfolios with better returns. The thesis aims to investigate this claim. The thesis examines the effect of diversifying into SRI in terms of risks and returns from the perspective of an Australian investor, on the performance of a portfolio consisting of stocks and bonds. In examining this aim, the thesis first identifies and evaluates the performance of the optimal SRI portfolio which consists of Australian and international SRI assets. Subsequently, the thesis constructs an optimal portfolio consisting of stocks, bonds and SRI based on the identified SRI portfolio, whose performance is then examined. In pursuit of the objective, the thesis conducts three interconnected studies. Firstly, an analysis of the inter-linkages between the Australian and other SRI markets worldwide. Secondly, an examination of the impact of international diversification on the performance of SRI portfolios based on an Australian perspective. Thirdly, an investigation of the impact of diversification into SRI assets on the performance of a portfolio of stocks and bonds.
Evaluation of growth, production and cold tolerance of four varieties of tilapia

viii Chapter 1: Introduction . 1 Varietal Characteristics.3 Worldwide Tilapia Production.5 Tilapia Production and Imports in the USA . 5 Tilapia in Louisiana . 6 Pond Culture . 9 Cage Culture . 10 Tank Culture . 11 References.13 Chapter 2: Growth of Four Tilapia Varieties in Recirculating Systems.17 Materials and Methods.19 Results.22 Discussion.24 References.26 Chapter 3: Growth of Seven Varieties of Tilapia in Fresh and Brackishwater Mesocosms.29 Materials and Methods.30 Results.32 Discussion.34 References.35 Chapter 4: Cold Tolerance of Four Tilapia Varieties . 37 Materials and Methods.39 Results.40 Discussion.52 References.54 Chapter 5: General Conclusions . 56 Performance Comparisons . 56 References.61 Appendix APooled Weights of 4 Tilapia Varieties in Recirculating Aquaculture Systems . 62
Concurrent application of ethyl formate and 1‐methylcyclopropene to control Tetranychus urticae on exported sweet persimmons (Diospyros kaki Thunb. ‘Fuyu’)

Extending the shelf life of fruits during post‐harvest storage and eradicating pests associated with quarantine issues could together comprise the key steps toward expanding the exportation of sweet persimmon in South Korea. Here we firstly investigated the concurrent application of ethyl formate (EF), a methyl bromide alternative fumigant, which is currently considered a beneficial and safe fumigant in quarantine use, and 1‐methylcyclopropene (1‐MCP), an anti‐ethylene compound that is broadly used in post‐harvest systems, on sweet persimmon. We also suggest the proper fumigation methods to be follow when using these compounds. Tetranychus urticae, an important quarantine pest, was inoculated under the calyx of sweet persimmon, and the fruits were then fumigated using 35.0 mg L−1 of EF for 6 h before and after treating with 1.0 μL L−1 of 1‐methylcyclopropene for 24 h under storage conditions of 5°C. Our results showed that concurrent treatments with 1‐MCP and EF could be suitable for commercial purposes by extending shelf life, delaying color changes and softening, and offering complete control of the target pest, Tetranychus urticae.
New Records for Sorex hoyi (American Pygmy Shrew) in Alabama

Abstract We report the first records of Sorex hoyi (American Pygmy Shrew) for Lawrence County, AL. We discovered 5 specimens in a specimen lot stored at Alabama A&M University. The shrews were incidental captures collected from pitfall traps used to study amphibian and reptile communities in the William B. Bankhead National Forest. A follow-up survey at the same sites during December 2015 resulted in the capture of 1 adult American Pygmy Shrew. Surveys at additional sites in Madison, Lawrence, and Winston counties, AL, during 2015–2016 yielded no further specimens. These records are 120 km southwest of the nearest records in Jackson County, AL, and expand the known southernmost edge of the geographic range by 35 km.
Electron microscopic evidence that Aip1 disintegrates cofilin-saturated F-actin domains in the presence of coronin

Cofilin is an essential actin filament severing protein necessary for fast actin turnover dynamics. Segments of actin bound to cofilin adapt an alternative twist. This configuration is stable, but boundaries between cofilin occupied and unoccupied polymer are weak and fragment. Coronin and Aip1 are two factors that promote cofilin mediated actin filament disassembly, but whether they simply accelerate the basic cofilin severing mechanism or alter the mode of filament disassembly is still being investigated. Using electron microscopy and spectroscopy, we show that coronin accelerates phosphate release from F-actin to stimulate highly cooperative cofilin binding on to the polymer creating long stretches with a hypertwisted morphology. We find that Aip1 attacks these hypertwisted regions along their length, not just the boundaries, causing sections to disintegrate into monomers. Therefore, coronin promotes cofilin binding to F-actin to generate longer segments of polymer that are themselves the substrates for Aip1 mediated disintegration, as opposed to simply creating more heterotypic junctions that would sever. The morphological characteristics of the disassembling filaments along with spectroscopic data showing the rapid liberation of actin monomers suggest that the combination of cofilin, coronin, and Aip1 might be triggering a more catastrophic mode of filament disassembly than severing.
Sharing genetic admixture and diversity of public biomedical datasets

Genetic ancestry and admixture are critical co-factors to study phenotype-genotype associations using cohorts of human subjects. Most publically available molecular datasets – genomes, exomes or transcriptomes - are however missing this information or only share self-reported ancestry. This represents a limitation to identify and re-purpose datasets to investigate the contribution of race and ethnicity to diseases and traits. we propose an analytical framework to enrich the meta-data from publically available cohorts with admixture information and a resulting diversity score at continental resolution, calculated directly from the data. We illustrate the utility and versatility of the framework using The Cancer Genome Atlas datasets indexed and searched through the DataMed Data Discovery Index. Data repositories or data contributors can use this framework to provide, as metadata, admixture for controlled access datasets, minimizing the work involved in requesting a dataset that may ultimately prove inadequate for a researcher’s purpose. With the increasingly global scale of human genetics research, research on disease risk and susceptibility would benefit greatly from the adequate estimation and sharing of admixture data following a framework such as the one presented.
Mapping clusters of chikungunya and dengue transmission in northern Tanzania using disease exposure and vector data

Background: Dengue and chikungunya are mosquito-borne viral diseases that are of public health importance throughout the tropical and subtropical regions of the world. Seasonal variations in transmission of these viruses have been suggested owing to the ecology of their mosquito vectors. However, little is known about the epidemiology of the diseases Tanzania. To address this gap, seasonal community-based cross-sectional surveys were undertaken to identify potential clusters of transmission in Hai district in northern Tanzania. Methods: Epidemiological and entomological data from two cross-sectional surveys were used to examine the spatial pattern of dengue and chikungunya transmission. Six villages namely, Boma Ng’ombe, Magadini, Rundugai, Nshara and Kware were involved in the study. Serological measures of dengue and chikungunya virus infections were derived using enzyme-linked immunosorbent assays, and all participants were geo-referenced to the household level using a global positioning system. Potential clusters of individual exposed to dengue and chikungunya virus , as well as clusters of Aedes mosquitoes in the wet and dry seasons were detected using SaTScan. All significant clusters (with p≤0.05) were mapped using ArcGIS. Results: A large, widely dispersed cluster of chikungunya exposed individuals was detected spanning Rundugai and parts of Magadini villages (RR = 2.58, p= 0.01), while no significant clustering was observed in the dry season. Spatial clusters of Aedes aegypti were detected in Rundugai in both the wet and dry seasons (RR = 2.56, p< 0.001 and RR = 2.24, p=0.05, respectively). In the dry season a small cluster was also detected in Kware (RR = 2.25, p=0.05). No significant clusters of dengue were detected in both seasons. Conclusion: Clusters of chikungunya-exposed individuals and Aedes mosquitoes indicate on-going transmission of chikungunya virus in Hai district of northern Tanzania.
Functional Roles of Matrix Metalloproteinases in Bone Metastatic Prostate Cancer

viii Chapter 1. Clinical and Biological Understanding and Study of Bone Metastatic Prostate Cancers . 1 1.1 Prostate Cancer and Bone Metastasis . 1 1.1.1 Castration Resistant Prostate Cancer (CRPC) . 2 1.1.2 Metastatic Castration Resistant Prostate Cancer (mCRPC) . 2 1.2 Organotropism and Outgrowth of Metastases in Bone . 3 1.2. 1 The Metastatic Cascade . 3 1.2. 2 What is Bone? 4 1.2. 3 Bone Stroma and Remodeling . 5 1.2. 4 Osteotropism . 7 1.2. 5 Osteomimicry . 8 1.2. 6 Understanding the Tumor Microenvironment . 9 1.2. 6.1 Pre-Metastatic Niche and Exosomes . 9 1.2. 6.2 SDF-1(CXCL12)/CXCR4 and similar signaling axes . 10 1.2. 7 The Vicious Cycle . 10 1.2. 7.1 Classical Explanation of Tumor-Bone Cellular Interactions . 11 1.2. 7.2 Integrating New Discoveries into the Vicious Cycle . 11 1.3 Approved Therapies for Bone Metastatic Prostate Cancer . 12 1.3. 1 Hormone Therapies . 14 1.3. 2 Chemotherapies. 15 1.3. 3 Microenvironment Targeted Therapies . 15 1.3. 4 Ongoing Clinical Challenges . 17 1.3. 4.1 Detection of Bone Metastases . 18 1.3. 4.2 Disseminated Tumor Cells and Dormancy . 19 1.3. 4.3 Heterogeneity . 22 1.4 Discussion . 23
Variability of Hydnum rufescens in Finland: three taxa hidden under one name - and appearance?

Recent observations revealed large variability in spores between materials collected as Hydnum rufescens Fr. New collections and herbarium specimens indicated that Finnish material can be divided into three entities based on spore characters. One of these, with ellipsoidal spores, was described as new by other workers. This species, Hydnum ellipsosporum Ostrow & Beenken, is not rare in Finland. In Finnish populations of H. rufescens s.str. spores are typically globose. Populations with intermixed broadly elliptical spores are more rare. Spore size in H. rufescens is clearly smaller than in H. umbilicatum Peck, in which spores are uniformly globose. A study of the holotype showed spore characters identical to the Finnish material. Hence, H. umbilicatum is claimed to be part of typical European mycofl ora; it seems to be fairly common in Finland. Observations made so far indicate that macromorphology and colours may be too variable for a defi nitive identifi cation in the fi eld. Some possibly helpful, mainly hymenial, characters are discussed. Two collections of H. rufescens are reported from Canada. Colour photographs of all the discussed taxa are provided.
ANTIDEPRESSANT POTENTIAL OF ISOLATED BIOACTIVE COMPOUND FROM BUTEA MONOSPERMA (LAM.) KUNTZE

Traditional or alternative medicine refers other than orthodox medicine. From time immemorial, plants have been utilized as corrective agents for a variety of diseases. Butea monosperma (Lam.) Kuntze is a generally utilized plant in Ayurveda. Butea monosperma (Palas) has a place with the family Fabaceae, developed freely in many parts of India. Different phytochemical constituents present are carbohydrates, alkaloids, tannins, flavonoids, steroids and terpenoids. Butea monosperma is traditionally utilized as a free radical scavenger, antistress, CNS stimulant, antigout, diuretic, antileprotic, anti-inflammatory, antiulcer, astringent and antihepatotoxic. Its flower is utilized to treat instances of expanded spleen, menstrual aggravations, consuming sensations and eye diseases.Effect of Isolated bioactive compound from Methanol Extract of Butea monosperma (Lam.) Kuntze (BMME) was studied for the duration of immobility by Forced Swim Test (FST) At the dose of 20 mg/kg isolated compound showed significant effect (p<0.05) for duration of immobility when compared with control group of animals. The monoamines are determined in mice brain to find out the altered levels of monoamines. It had been suggested that an increase in both swimming and climbing behaviors in the FST occurs when the animal is treated by a drug which increases NA and DA levels in the nerve terminals. An increase in NA and DA could be by inhibition of MAO activity in the brain.
Benthic macroinvertebrate population distributions in relation to the C. P. Crane power plant thermal discharge : final report

Benthic macroinvertebrates (0.5 mm sieve) were sampled quarterly during the period June 1979-April 1980 in the oligohaline habitat in the vicinity of the C. P. Crane Generating Station, and in three reference areas in tributaries of Chesapeake Bay. Communities were distinguished according to sediment type (sand vs mud groups) and water depth (creek vs river-bay assemblages). The mud community in tiLe immediate power plant discharge zone exhibited late summer depressions of numbers of species, species diversity, and species richness. On the species level fi.ve types of responses to the discharge were suggested by spatial and temporal distributions: (1) mitigation of a winter population reduction (Rangia cuneata in sand areas near the plant); (2) acceleration of growth or development (increase in R. cuneata shell size with increasing proximity to the plant; accelerated spring population buildups of Scolecolepides viridis, Leptocheirus plumulosus, Tanytarsus sp., and Tubificidae near the discharge); (3) transport from the intake to the discharge waters of individuals entrained in the cooling water (S. viridis in April and Coelotanypus sp. in September); (4) extension of range (presence of creek dipterans at river stations downstream from the discharge}; (5) intensification of summer population declines near the discharge (S. viridis, ~· plumulosus, Xenochironomus sp., Polypedilum sp.). Affected species exhibited widened or narrowed annual ranges of population density, relative to populations in oligohali.ne reference areas. The power plant cooling water maintains elevated salinity as well as temperature in the discharge zone. In the absence of the • salinity effect the benthos would probably resemble the connnunity in
From Tick Data to Semimartingales

Tick-by-tick asset price data exhibit a number of empirical regularities, including discreteness, long periods where prices are flat, periods of price moves of alternating plus and minus one tick, periods of rapid successive price moves of the same sign, and others. This paper proposes a framework to examine whether and how these microscopic features of the tick data are compatible with the typical macroscopic continuous-time models, based on Ito semimartingales, that are employed to represent asset prices. We construct in particular tick-by-tick models that deliver by scaling macroscopic semimartingale models with stochastic volatility and jumps.
DriverPower: Combined burden and functional impact tests for cancer driver discovery

We describe DriverPower, a software package that uses mutational burden and functional impact evidence to identify cancer driver mutations in coding and non-coding sites within cancer whole genomes. Using a total of 1,373 genomic features derived from public sources, DriverPower’s background mutation model explains up to 93% of the regional variance in the mutation rate across a variety of tumour types. By incorporating functional impact scores, we are able to further increase the accuracy of driver discovery. Testing across a collection of 2,583 cancer genomes from the Pan-Cancer Analysis of Whole Genomes (PCAWG) project, DriverPower identifies 217 coding and 95 non-coding driver candidates. Comparing to six published methods used by the PCAWG Drivers and Functional Interpretation Group, DriverPower has the highest F1-score for both coding and non-coding driver discovery. This demonstrates that DriverPower is an effective framework for computational driver discovery.
Molecular and Morphologicalgenetic Diversity of Potato (Solanum Tuberosum) Clones Conserved in Ethiopia Using Simple Sequence Repeat (Ssr) Markers.

v TABLE OF CONTENTS . vii LIST OF TABLES . xi LIST OF FIGURES . xii LIST OF PLATES . xiii LIST OF APPENDIX . xiv ACRONYMS . xv CHAPTER 1: INTRODUCTION . 1 1.1 Background of the study . 1 1.1.1 Potato Production Constraints in Ethiopia. 1 1.1.2 Agronomic practices of potato in Ethiopia . 2 1.1.3 Potato breeding strategies in Ethiopia . 3 1.2. Statement of the problem . 7 1.3 Justification . 7 1.4. General objective of the study:. 8 1.4. 1. Specific objectives . 8 1.5. Significance of the study . 8 1.6 Hypothesis . 8 CHAPTER 2: LITERATURE REVIEW . 9 2.1. Origin and Distribution of Potato . 9 2.2. Taxonomy of Potato (Solanum tuberosum L.) . 9 2.2.1. Taxonomic hierarchy of Potato . 9 viii 2.3. Botany of potato . 10 2.3.1 Reproduction . 11 2.4 Ecological requirements of potato. 11 2.5 Utilization of potato . 12 2.5. 1 Food Uses . 12 2.5. 2 Non-Food Uses . 12 2.6. Nutritional content of potato . 13 2.7. Importance of genetic diversity of potato . 14 2.8 Genetic diversity and its implication in crop (Potato) improvement . 14 2.9. Molecular markers for diversity studies in crops . 15 2.9. 1. Restriction Fragment Length Polymorphism (RFLP) . 16 2.9. 2. Inter-Simple Sequence Repeats (ISSRs) . 17 2.9. 3 Random amplified polymorphic DNA (RAPD) . 17 2.9. 4 Amplified fragment length polymorphism (AFLP). 18 2.9. 5. Simple Sequence Repeats (SSRs). 19 CHAPTER THREE: Materials and Methods . 21 3.1. Plant material. 21 3.2. Plant material collection and procedures for molecular genetic diversity study. 22 3.2.1 DNA extraction. 22 3.2.2 Genomic DNA quality and quantity detection . 22 3.2.3 Primer selection and polymerase chain reaction (PCR) . 23 3.2.4 Gel electrophoresis of PCR products. 23 3.2.5 Allele scoring and genetic data analysis . 24 3.3. Morphological Data collection and analysis . 25 Chapter Four: RESULTS . 26
Functional-drink rich in antioxidant cardamom-rhizome (Amomum cardamomum willd) suppresses inflammation and improves lipid profile

The aim of this research was to know the effect of functional drink rich in antioxidant cardamom rhizome (Fd-Carrhi) on level of IL-6, C-RP, and lipid profile of atherosclerotic. A total of 30 women with atherosclerosis, age 40-65 years old, hypertension, hypercholesterolemia, hypertriglyceridemia, lived in Purwokerto, Banyumas, Central Java, Indonesia, and were willing to sign informed consent, recruited as research subjects. They consumed simvastatin from doctors, divided by 3 groups of 10 people each. Group I, given Fd-Carrhi; II, placebo; and III, only simvastatin, for 2 months. As many as 100 ml of Fd-Carrhi or placebo were given every morning. Blood samples were taken 3 times, 1 ml, at baseline, 1 and 2 months after intervention. Blood plasma was determined levels of IL-6, C-RP, as well as total cholesterol (total-c), triglycerides (TG), LDL-c, and HDL-c. Result showed Fd-Carrhi versus placebo significantly decreased plasma level of IL-6, C-RP, total-c, and LDL-c, and otherwise increased HDL-c, but no differences were seen in TG. The findings clearly support Fd-Carrhi inhibit the development of atherosclerosis towards cardiovascular heart diseases (CHD) by suppressing IL-6 and CRP levels, and improving lipid profile.