Miracle-dz/UniFAR-FTUs huggingface dataset:
A robust decentralized controller design for inverter-based Microgrids with dynamic loads

We present a model of an inverter-based Microgrid with dynamic loads. The influence of the dynamic loads on the system stability in terms of frequency and voltage is deduced from their frequency domain responses. Then, based on the linear matrix inequality (LMI) technique and the small-gain theorem, a robust decentralized control approach is introduced to guarantee stability of the whole Microgrid in the presence of load influences during operation and zero steady-state frequency deviation. The control approach contributes the peer-to-peer and plug-and-play architecture of Microgrids as well as promotes the possibility of power sharing between the generation units of the system.
Predicting student's performance using CART approach in data science

In technical graduate courses like engineering, it is very important that students are monitored during their first year. It is important for all technical graduates to have a good programming insight. Still, a student shying away from the core subjects like programming is common phenomena in engineering colleges nowadays. It is thus necessary to keep track of students' performance during the first year of the course especially. During semester beginning, poor performance further creates disinterest in students and hence the end result is low whether it is on semester card or it is their knowledge level. It gives a scope for us to apply data science techniques to analyze and predict a student's performance. To address this problem we propose a system which will make use of the decision tree approach to predict a student's performance. Based on student's current performance and some measurable past attributes the end result can be predicted to classify them among good or bad performers. It will thus enable a faculty to pay attention to the weak students and plan sessions for them accordingly. A student's interest in programming or other core subjects can be monitored and encouraged as needed.
Continuous inhibition of 11β‐hydroxysteroid dehydrogenase type I in adipose tissue leads to tachyphylaxis in humans and rats but not in mice

11β‐hydroxysteroid dehydrogenase type I (11β‐HSD1), a target for Type 2 diabetes mellitus, converts inactive glucocorticoids into bioactive forms, increasing tissue concentrations. We have compared the pharmacokinetic‐pharmacodynamic (PK/PD) relationship of target inhibition after acute and repeat administration of inhibitors of 11β‐HSD1 activity in human, rat and mouse adipose tissue (AT).
Government admits mental health service problems

One in three health authorities in England will not be able to deliver comprehensive mental health services for at least another year, the government has admitted. In its review of mental health care around the country, published last week, the NHS Executive cites 33 health authorities “whose plans require service improvements beyond the end of 1996-7. ” The review of mental health purchasing, set up in August 1995 at the request of the health minister, …
Why Adjuvant Trastuzumab Led to Better Outcomes in Women with High‐Risk HER‐2‐Positive Breast Cancer

To the Editor: Recently three important studies related to adjuvant use of trastuzumab in HER-2-positive operable breast cancer have been reported (1,2) (Fig. 1). In the first report, pooled analysis of two U.S. trials, the National Surgical Adjuvant Breast and Bowel Project (NSABP) B31 and the North Central Cancer Treatment Group (NCCTG) N9831, was given (1). Compared with the control group consisting of doxorubicin and cyclophosphamide followed by paclitaxel, the concurrent use of trastuzumab combined with the standard regimen of doxorubicin and cyclophosphamide followed by paclitaxel decreased the risk of tumor recurrence by 52%. Joint analysis also showed a significant benefit in overall survival with a relative reduction of 33% (p = 0.0015). The third study, known as the Herceptin Adjuvant (HERA) trial, involved many countries outside the United States and looked at the efficacy of trastuzumab monotherapy given for 12 years after completion of adjuvant chemotherapy with or without radiation. In this trial, trastuzmab was given every 3 weeks (2). After a median follow-up of 1 year, the trastuzumab arm had a significantly improved disease-free survival, with a 46% relative risk reduction of tumor recurrence (p < 0.0001). The efficacy of adjuvant trastuzumab in these trials may be explained in several ways. First, trastuzumab has a direct effect on HER-2-positive breast cancer cells, leading to G1 arrest, angiogenesis inhibition, or antibodydependent cellular toxicity (3). Second, trastuzumab may have a synergy with paclitaxel (4). Indeed, the combination arm showed better disease-free survival than the sequential arm in the NCCTG N9831 trial. Third, there are also preclinical data showing the synergy between trastuzumab and radiotherapy (5). Trastuzumab was given during radiotherapy in U.S. trials. Fourth, hormone receptor-positive patients in these trials received endocrine treatment, mostly tamoxifen. Some studies revealed that growth factors, specifically HER-2, play an important role in the development of primary and secondary endocrine resistance (6). Therefore the trastuzumab and tamoxifen combination might have reversed this resistance. Finally, HER-2 expression plays an important role in the development of estrogen receptor (ER)-negative breast cancer. Therefore blocking HER-2 by trastuzumab
Active Matrix Color-LCD on 75  $\mu$m Thick Flexible Glass Substrates

We have demonstrated a full color 4-in quarter-VGA amorphous silicon active-matrix (AM) LCD (AM-LCD) with 75 μm thick flexible glass backplane and frontplane substrates. The device was built directly on the flexible glass without using a processing carrier or additional protective layers. The overall thickness of the LC cell is <; 170 μ m. Process modifications were made to accommodate the flexibility and reduced thickness of the substrate. These process changes were related to: thin film deposition, photolithography, cell assembly and filling, glass scribing, and driver bonding. The achieved results indicate that the incorporated flexible glass substrates are compatible with the fabrication of high quality color AM-LCDs.
Generalized noninterpolatory rules for Cauchy principal value integrals

Consider the Cauchy principal value integral I(kf; λ)=∫ −1 1 k(x)f(x)/x-λ dx, −1<λ<1. If we approximate f(x) by Σ N =0 a j p j (x; w) where {p j } is a sequence of orthonormal polynomials with respect to an admissible weight function w and a j =(f, p j ), then an approximation to I(kf; λ) is given by Σ N =0 2jI(kp j ; λ). If, in turn, we approximate a j by a j m =Σ i=1im f(x im )p j (x im ), then we get a double sequence of approximations {Q m N (f; λ)} to I(kf; λ). We study the convergence of this sequence by relating it to the sequence of approximations associated with I(wf; λ) which has been investigated previously
Search Engine Query Recommendation - Using SNA over Query Logs with User Profiles

Recommending the adequate query in search engine for a specific user on the web is still a challenge even for recommender systems today with social networks incorporated. In this paper we present a query recommender that in addition to relying on similarity of the actual query posted by current user to queries in a query log in search engine, it also bases on social network analysis (SNA) to first find most similar users to the current user based on their profiles, and then recommend their most similar queries to current user. Calculation of the similarity of users follows an existing approach for Points of Interest (POIs) recommendation, which applies certain SNA ranking algorithms over concurrent users based on their social profiles in the login session.
Review: ethidium fluorescence assay. Part II. Enzymatic studies and DNA-protein interactions.

Almost all DNA and RNA metabolizing enzymes can be assayed rapidly and very sensitively by exploiting the enhanced fluorescence of ethidium intercalated into duplex DNA or RNA. Denatured DNA and natural RNAs contain duplex regions due to intramolecular hydrogen-bonding and can also be sensitively measured. Where the product is truly single-stranded (e.g. dTn) it can be assayed by adding the appropriate complementary strand (e.g. dAn or rAn). Some of the assays described provide information not readily obtained by other assay procedures. Among the enzymes readily assayed are DNA and RNA polymerases, terminal deoxynucleotidyl transferases, nucleases of all varieties (e.g. single-strand specific, endonucleases including for example AP endonucleases, exonucleases, RNase H, etc.), ligases, topoisomerases including gyrases, and indirectly enzymes such as proteases and superoxide dismutase. DNA binding proteins such as histones and helix destablizing proteins can also be quantitatively assayed.
Event detection in Tweets

103 Event detection in Tweets Andrei-Bogdan Baran “Alexandru Ioan Cuza” University, Faculty of Computer Science General Berthelot, No. 16 andrei.baran@info.uaic. ro Adrian Iftene “Alexandru Ioan Cuza” University, Faculty of Computer Science General Berthelot, No. 16 adiftene@info.uaic. ro ABSTRACT Twitter is among the fastest-growing online social networking services, with more than 140 million users producing over 400 million tweets per day. It enables users to post status updates (tweets) about a huge variety of topics to a network of followers using various communication services such as cell phones, e-mails, Web interfaces, or other third-party applications. Monitoring and analyzing this rich and continuous usergenerated content can lead to obtaining valuable information about local and global news and events, because virtually, any person witnessing or involved in any event is nowadays able to disseminate realtime information, which can reach the other side of the world as the event unfolds.
MaVis: Feature-Based Defects Visualization in Software Testing

Software testing is a significant investigation during software development, which is conducted to produce information about the quality of the product or service under test. An automatic visualization tool will greatly improve the effectiveness and efficiency of the analysis of testing results. Current visualization tools focus on defects location and version maintenance, but lack of consideration of visualizing system features, version management and visualizing analytical data. In this paper, we propose MaVis, which is a novel visualization tool to help testers easily and quickly understand and locate defects in system features.
A Generalized Loss Analysis Algorithm of Power Semiconductor Devices in Multilevel NPC Inverters

In this paper, a generalized power loss algorithm for multilevel neutral-point clamped (NPC) PWM inverters is presented, which is applicable to any level number of multilevel inverters. In the case of three-level inverters, the conduction loss depends on the MI (modulation index) and the PF (power factor), and the switching loss depends on a switching frequency, turn-on and turn-off energy. However, in the higher level of inverters than the three-level, the loss of semiconductor devices cannot be analyzed by conventional methods. The modulation depth should be considered in addition, to find the different conducting devices depending on the MI. In a case study, the power loss analysis for the three- and five-level NPC inverters has been performed with the proposed algorithm. The validity of the proposed algorithm is verified by simulation for the three-and five-level NPC inverters and experiment for three-level NPC inverter.
Effect of Smooth Microchannel Cross Section Shape on Friction Factor

Pressure drop is important in performance of MEMS devices with microchannel. The geometry of microchannel will have important significant effect on of pressure drop and friction factor. The effect of four cross section shapes of microchannel on friction factors is investigated. It is found that the friction factors are significantly affected by the cross section shape. The four cross section shapes have obvious different friction factors under various hydraulic diameters. When the microchannel is triangular shape, the larger hydraulic diameter will induce more significant effect on friction factor. However, the change of hydraulic diameter has less significant effect on friction factor in rectangular microchannel. The effect of increasing hydraulic diameter is not significant and the friction factors decrease nonlinearly as the Reynold's numbers increase
Orthostatic intolerance in the morning DIURNAL VARIATION IN TIME TO PRE-SYNCOPE AND ASSOCIATED CIRCULATORY CHANGES DURING A CONTROLLED ORTHOSTATIC

1 Research Institute of Sport and Exercise Science, Liverpool John Moores University, UK 2 Department of Physiology, University of Otago, Dunedin, New Zealand 3 School of Physical Education, University of Otago, Dunedin, New Zealand 4 Physiological Rhythms Unit, Department of Surgery and Anaesthesia, University of Otago, Wellington, New Zealand 5 Department of Human Kinetics, Faculty of Health and Social Development, University of British Columbia Okanagan, Kelowna, Canada
Identification of individuals by analysis of biallelic DNA markers, using PCR and solid-phase minisequencing.

We have developed a new method for forensic identification of individuals, in which a panel of biallelic DNA markers are amplified by the PCR, and the variable nucleotides are detected in the amplified DNA fragments by the solid-phase minisequencing method. A panel of 12 common polymorphic nucleotides located on different chromosomes with reported allele frequencies close to . 5 were chosen for the test. The allele frequencies for most of the markers were found to be similar in the Finnish and other Caucasian populations. We also introduce a novel approach for rapid determination of the population frequencies of biallelic markers. By this approach we were able to determine the allele frequencies of the markers in the Finnish population, by quantitative analysis of three pooled DNA samples representing 3,000 individuals. The power of discrimination and exclusion of the solid-phase minisequencing typing test with 12 markers was similar to that of three VNTR markers that are routinely used in forensic analyses at our institute. The solid-phase minisequencing method was successfully applied to type paternity and forensic case samples. We also show that the quantitative nature of our method allows typing of mixed samples.
[Off-line exhaled nitric oxide measurement in children].

INTRODUCTION The objective is to test the validity of a tool allowing an offline measurement of the fraction of expired nitric oxide (FENO). The device is a T-tube on which a pressure gauge allows the control of the expiratory flow and whose two side branches have a gauge such as the bags assembled on each one of them fill successively. METHODS The first phase aims to check that the sample collected in the second bag answers the criteria of analysis of NO during a single expiration and that this measurement can be delayed. The second phase aims to test the feasibility and the repeatability of the offline analysis in children. RESULTS The device makes it possible to stabilize the expiratory flow at 100 ml/s. The NO concentration in the second bag is stable during 6 hours. The intra measurement coefficient of variation of delayed FENO 0.1 is 7% (N = 19). CONCLUSION A off line measurement of the exhaled nitric oxide is reliable in asthmatic children.
Characterization of photoresponse in single Si nanowire p-n junction using conductive atomic force microscopy

Photoresponse and electrical conduction properties of vertical single NW p-n junction was investigated using a conductive atomic force microscopy (C-AFM). Silicon NWs with 200 nm diameter were fabricated by e-beam lithography and dry etching. The C-AFM measurement shows ∼10 times enhancement in the photocurrent.
Monte Carlo simulation of a computed tomography x-ray tube

The dose delivered to patients during computed tomography (CT) exams has increased in the past decade. With the increasing complexity of CT examinations, measurement of the dose becomes more difficult and more important. In some cases, the standard methods, such as measurement of the computed tomography dose index (CTDI), are currently under question. One approach to determine the dose from CT exams is to use Monte Carlo (MC) methods. Since the patient geometry can be included in the model, Monte Carlo simulations are potentially the most accurate method of determining the dose delivered to patients. In this work, we developed a MC model of a CT x-ray tube. The model was validated with half-value layer (HVL) measurements and spectral measurements with a high resolution Schottky CdTe spectrometer. First and second HVL for beams without additional filtration calculated from the MC modelled spectra and determined from attenuation measurements differ by less than 2.5%. The differences between the first and second HVL for both filtered and non-filtered beams calculated from the MC modelled spectra and spectral measurements with the CdTe detector were less than 1.8%. The MC modelled spectra match the directly measured spectra. This works presents a first step towards an accurate MC model of a CT scanner.
Inflammatory Bowel Disease: Influence and Implications in Reproduction

Abstract:The incidence and prevalence of inflammatory bowel disease (IBD) continues to rise with time, signifying its emergence as a global disease. Clinical onset of IBD, comprising Crohn's disease and ulcerative colitis, typically occurs before or at peak reproductive age. Although active disease in female patients is associated with reduced fertility and adverse obstetric outcomes in pregnancy, the molecular mechanisms underlying this altered reproductive course, and its impact on IBD transmission to offspring, remain poorly understood. Clinical and experimental studies have now begun to elucidate the hormonal, environmental, and microbial factors that modulate immune-reproductive cross talk in IBD and define their impact on maternal health, fetal development, and heritability of disease risk. Evolving insight into maternal–fetal imprinting in IBD has important implications for patient counseling and disease management during pregnancy and may help predict clinical outcomes for both mother and child.
Title : De novo deletion in MECP 2 in a monozygotic twin pair : a case report Authors

Rett syndrome (RTT) is a severe, progressive, neurodevelopmental disorder predominantly observed in females, that leads to intellectual disability. Mutations and gross rearrangements in MECP2 account for a large proportion of cases with RTT. We investigated 13 year old, monozygotic twin females with RTT and some noticeable differences in development using a combinatorial approach of sequencing and Taqman assay. Monozygosity status of the twins was confirmed by informative microsatellite markers. The twins shared a de novo deletion in exon 3 in the MBD domain of MECP2. To the best of our knowledge, this is only the second report of genetic analysis of a monozygotic twin pair.
Robust EM-based detection of BICM-OFDM transmissions in the presence of narrowband interference

Future wireless communications systems are expected to coexist with different commercial applications over the same frequency bands. This gives rise to co-channel interference, which strongly affects the error-rate performance. In this work, an orthogonal frequency-division multiplexing system with bit-interleaved coded-modulation is considered and the problem of data detection in the presence of unknown narrowband interference (NBI) is addressed. In particular, an iterative detector that operates according to the expectation-maximization algorithm is derived under the assumption that the interference power on each subcarrier can be modeled as a random variable with an inverse gamma distribution. Computer simulations indicate that the proposed solution is remarkably robust to NBI and outperforms existing alternatives in severe interference environments.
Differential function of Listeria monocytogenes listeriolysin O and phospholipases C in vacuolar dissolution following cell‐to‐cell spread

We investigated the role of listeriolysin O (LLO) and the bacterial phospholipases PI‐PLC and PC‐PLC in cell‐to‐cell spread of Listeria monocytogenes. We showed that LLO is essential for cell‐to‐cell spread in primary murine macrophages. Electron micrographs revealed that in the absence of continued LLO expression, bacteria remain trapped in secondary spreading vacuoles having either a double or single membrane. In bacteria lacking PI‐PLC and PC‐PLC, cessation of LLO expression after initiation of infection resulted in a significant increase in the proportion of bacteria trapped in double‐membrane compartments. We propose that the bacterial phospholipases are involved in the dissolution of the inner membrane of the spreading vacuole, yet are not sufficient for disruption of the outer membrane. As a consequence, we identified LLO as a key factor in the disruption of the outer membrane. This model is consistent with the observation that LLO is dispensable for cell‐to‐cell spread from human macrophages into a cell type in which LLO is not required for vacuolar escape. These data suggest that during human infection, spreading of L. monocytogenes to distant organs is likely to occur even in the absence of LLO expression, and that the bacterial phospholipases may be sufficient to mediate continued cell‐to‐cell spread.
Axonal loss and blood flow disturbances in the natural course of indirect traumatic optic neuropathy

Background Indirect traumatic optic neuropathy (TON) is an acute injury of the optic nerve associated with severe visual dysfunction, which may be a result of secondary mechanical injury and vascular disorder of the optic nerve due to trauma. We analyzed the natural course of axonal loss and blood flow disturbances in patients with indirect TON to find a possible therapeutic window. Methods A cohort of 54 patients with indirect TON recruited between October 2008 and October 2010 at Beijing Tongren Hospital was retrospectively analyzed. The patients were divided into no light perception group (NLP) and better than NLP (btNLP) group. Specifically, the thickness of the retinal nerve fiber layer (RNFL) measured by spectral domain optical coherence tomography (SD‐OCT), and hemodynamic parameters of the ophthalmic artery (OA), central retinal artery (CRA) and posterior ciliary artery (PCA) were determined. Results Two weeks after injury, there was a statistically significant decrease in the thickness of RNFL in the btNLP group as compared with the fellow control eyes (P <0.05). In contrast, in the NLP group, RNFL thickness slightly increased for 2 weeks following injury, then overtly reduced after 4 weeks (P <0.05). Peak systolic velocity (PSV) of CRA was significantly decreased 4 weeks after injury (P<0.05) in both the NLP group and btNLP group (P <0.05). The thickness of RNFL in the NLP group was negatively correlated with PSV of CRA after 1 week of injury (P <0.05, r=‐0.962). Conclusions SD‐OCT is a useful supplement in detecting the axonal loss in TON. The dynamic change of the thickness of RNFL appears to correlate with the hemodynamic disturbances in the natural course of TON. The first 2 weeks following an injury is critical and should be considered as the therapeutic window for TON patients.
Direct patterning of vortex generators on a fiber tip using a focused ion beam.

The realization of spiral phase optical elements on the cleaved end of an optical fiber by focused ion beam milling is presented. A focused Ga+ ion beam with an acceleration voltage of 30 keV is used to etch continuous spiral phase plates and fork gratings directly on the tip of the fiber. The phase characteristics of the output beam generated by the fabricated structures measured via an interference experiment confirmed the presence of phase singularity in the output beam. The devices are expected to be promising candidates for all-fiber beam shaping and optical trapping applications.