Miracle-dz/UniFAR-FTUs huggingface dataset:
How Patients Understand Diabetes Self-Care

Millions of people with diabetes must control their blood glucose system through diet, medication, and exercise. To learn how patients understand this daunting task, we conducted Cognitive Task Analysis interviews with 20 participants with type II diabetes. The interviews queried initial education, experiences with self-care, understanding of the disease, and treatment adherence. Participants who showed greater expertise in their articulation of problem detection strategies, functional relationships, and problem solving strategies were more effective self-managers. Several mental models of diabetes self-management were identified. Human Factors advances that have helped pilots control planes, may also help patients to develop functional models of blood glucose control and cope with the complexities of self-care. These advances may also help people facing other chronic medical conditions and complex life challenges.
Modelling population-level drug use with demographic and geographic approaches and techniques

Within the field of pharmacoepidemiology and drug safety as in the wider field of epidemiology focus has been on individual-level studies. However, the impact of drug use for the society as a whole cannot directly be inferred from such studies and population-level causal designs are required. For example, for health policy it is crucial to know the role of drugs in affecting regional, national or international morbidity and mortality trends. Similarly, predicting (future) levels of local health care and drug use is essential for prevention purposes, targeted allocation of care and meeting health demands. Moreover, actual end users of drugs in society may largely differ from clinical trial populations [1,2] used to study the efficacy of drugs for registration purposes [3].
The Impacts of Gianotti-Crosti Syndrome (Papular Acrodermatitis of Childhood) on the Quality of Life of Children

Background : Gianotti-Crosti syndrome (GCS) is a self-remitting eruption related to viral infections. Ribavirin has been reported to be effective in treating severe GCS. Before clinical trials on antiviral agents, the magnitude of GCS affecting the quality of life in children should be ascertained. Aim: To investigate the impact of GCS on the QOL of children. Methods: Our setting was a teaching clinic. We validly translated the Children Dermatology Life Quality Index into Chinese. We recruited all children aged five to 16 years diagnosed with GCS over two years. For each child with GCS, we recruited the next age-and-sex pair-matched child consulting us for atopic dermatitis (AD), and the next age-and-sex pair-matched child brought to consult us for problems unrelated to the skin as controls. All study and control subjects completed the CDLQI. Results: 23 children were GCS and 46 children as controls were recruited. The impacts of GCS on children were significantly higher than children brought to consult us for problems unrelated to the skin ( P < 0.05), with the parameters symptoms and feelings , leisure , school or holidays , and treatment mostly affected. However, the scores were low. Four (17%) study subjects and none (0%) in the second control had total CDLQI higher than 30%. The difference is insignificant (RR: inapplicable; P = 0.11).
Occupational Therapy and Occupational Participation in Community Dwelling Older Adults: A Review of the Evidence

Abstract Aims: To review recent occupational therapy literature to establish the current level of evidence on how occupation may influence participation and may prevent or reduce social isolation in community dwelling older adults aged 60 years and over. Methods: Pertinent electronic databases were comprehensively searched using a guiding search strategy and inclusion criteria. Data extraction and quality assessment was conducted on included studies. Results: 14 studies were included in the review. The occupational domains within the studies that contributed to social participation or social isolation included instrumental activities of daily living, education, leisure, work and social participation. Conclusions: Evidence is emerging within recent literature to support a positive relationship between occupations, social participation and the prevention of social isolation in community dwelling older adults aged 60 years and over. Evidence supports the highly relevant and valuable role of occupational therapy in facilitating healthy aging through supporting social participation and addressing social isolation for the increasingly aging global population.
Developments and insights into the analysis of the human microbiome

Abstract The intense research focused on the human microbiome during the last years has shed some light on this mostly uncharacterized part of the human body. The constantly improving sequencing technologies have additionally eased the process of collecting a large amount of genome data from metagenomics samples. Using these methods, large studies with sufficient number of subjects have started to reveal the implications of our microbiome in health and disease. Here, we present a review on the last developments of sequencing technology together with an overview on the findings in this fast-evolving field of science. Zusammenfassung In den letzten Jahren haben sich immer mehr wissenschaftliche Untersuchungen auf das humane Mikrobiom konzentriert, um diesen noch meist unbekannten Teil des menschlichen Körpers intensiver zu durchleuchten. Die konstante Verbesserung der verfügbaren Sequenziertechnologien hat weiterhin die Verfügbarkeit von großen Mengen an genomischen Daten deutlich erleichtert. Hiermit konnten große Studien mit einer genügend großen Anzahl an Probanden beginnen zu beschreiben, welche Auswirkungen unser Mikrobiom nicht nur in Verbindung mit Krankheiten sondern auch auf unseren gesunden Körper hat. In diesem Übersichtsartikel beschreiben wir die neuesten Entwicklungen in den Sequenziertechnologien zusammen mit einer Darstellung neuester Erkenntnisse aus diesem Forschungsbereich, welcher sich immer schneller entwickelt.
The Diagnosing and Staging of Idiopathic Pulmonary Fibrosis

Idiopathic pulmonary fibrosis (IPF) is the most frequently occurring interstitial lung disease. The condition tends to be inexorably progressive and conveys a poor prognosis with a median survival of 2.8 to 4.2 years. The dismal prognosis coupled with recent exciting clinical trial advances have made it more important than ever that IPF is correctly distinguished from other interstitial lung diseases at an early stage. Correct diagnosis of IPF relies on the careful integration of clinical evaluation, high-resolution computerized topography appearances, and in the minority of cases, surgical lung biopsy findings. The need to incorporate information from different sources has led to multidisciplinary team (MDT) assessment gaining primacy in the diagnosis of IPF. Clinical investigations in IPF, including lung function testing, 6-minute walk, and echocardiography, also enable an accurate assessment to be made concerning baseline disease severity and permit judgments to be made about short to medium-term prognosis. This article addresses the key issues encountered by physicians when assessing a patient with suspected IPF and highlights the value of key clinical investigations in the evaluation of patients with this devastating disease.
FOCUS GROUP COMO PROCESO EN INGENIERÍA DE SOFTWARE: UNA EXPERIENCIA DESDE LA PRÁCTICA

La investigacion en Ingenieria de Software es un area relativamente nueva. Recientemente se han comenzado a usar metodos empiricos para soportar las diferentes etapas del proceso de desarrollo software. Este es el caso de grupos focales (Focus Group), un metodo validado con sufi ciencia en areas relacionadas como ciencias sociales, de la salud, psicologia, administrativas, entre otras. El presente articulo propone un proceso debidamente estructurado para la aplicacion de focus group en Ingenieria de Software como tecnica de evaluacion de resultados y lo aplica a un caso especifi co de investigacion en el proceso de modelado de estudiante en Sistemas Adaptativos de Aprendizaje (Adaptive Learning Systems – ALS). Los resultados obtenidos demuestran los benefi cios y desafios en la utilizacion del metodo de grupos focales en el estudio de caso propuesto.
Are we sleeping on the job? Insomnia among men with prostate cancer

Prostate cancer is one of the most commonly diagnosed cancers in men and almost half of male cancer survivors in the US have had a prostate cancer diagnosis. Insomnia is common among cancer patients and survivors. There is evidence that cognitive behavioural therapy can be used to effectively manage insomnia among women with breast cancer. The aim of this review was to investigate the prevalence, risk factors and management of insomnia among men with prostate cancer. The effect of insomnia on the psychological health and health-related quality of life of these patients and/or survivors is also discussed. Increased awareness and knowledge of this symptom among men with prostate cancer may facilitate improved diagnosis, and management of insomnia in this large population. This in turn may improve the health-related quality of life of these men. Therefore, research into the effective management of insomnia among men with prostate cancer is essential.
Spirits of a Drum Beat: African Caribbean Traditional Healers and their Healing Practices in Toronto

Abstract African Caribbean communities in the diaspora use a wide variety of traditional healing practices, such as Voodoo, Spiritism, Espiritismo, Santeria, Spiritual Baptist, Maat and Christian Pentecostal, and many others. Outside of the communities directly involved in these healing traditions, not much is known about many of these healers and the kinds of healing practices they engage in. This research explores and offers insights into African Caribbean traditional healers and their healing practices in the GTA (Greater Toronto Area), in Canada. Five individuals (three males and two females) who identified as African Caribbean traditional healers and practiced in the Greater Toronto Area were interviewed. The healers described their healing practices, shared issues related to the assessment and treatment of patients' presenting problems, and discussed collaboration between Western healthcare practitioners and themselves. Grounded theory was used to analyse the transcripts.
from the

The exploration of Earth ’ s terrestrial subsurface biosphere has led to the discovery of several new archaeal lineages of evolutionary signi ﬁ cance. Similarly, the deep subsea ﬂ oor crustal biosphere also harbors many unique, uncultured archaeal taxa, including those belonging to Candidatus Hydrothermarchaeota, formerly known as Marine Benthic Group-E. Recently, Hydrothermarchaeota was identi ﬁ ed as an abundant lineage of Juan de Fuca Ridge ﬂ ank crustal ﬂ uids, suggesting its adaptation to this extreme environment. Through the investigation of single-cell and metagenome-assembled genomes, we provide insight into the lineage ’ s evolutionary history and metabolic potential. Phylogenomic analysis reveals the Hydrothermarchaeota to be an early-branching archaeal phylum, branching between the superphylum DPANN, Euryarchaeota, and Asgard lineages. Hydrothermarchaeota genomes suggest a potential for dissimilative and assimilative carbon monoxide oxidation (carboxydotrophy), as well as sulfate and nitrate reduction. There is also a prevalence of chemotaxis and motility genes, indicating adaptive strategies for this nutrient-limited ﬂ uid-rock environment. These ﬁ ndings provide the ﬁ rst genomic interpretations of the Hydrothermarchaeota phylum and highlight the anoxic, hot, deep marine crustal biosphere as an important habitat for understanding the evolution of early life.
A Cooperative Imbalance Compensation Method for Distributed-Generation Interface Converters

Distributed generation has attracted great attention in recent years, thanks to the progress in new generation technologies and advanced power electronics. The Micro-grid has been a successful example by integrating various generation sources with the existing power distribution network through power electronics converters. The Micro-grid converters are required to operate in a de-centralized fashion, and the power- frequency droop control and reactive power-voltage droop control have been adopted for this purpose. In this paper, a droop control technique for imbalance compensation within the three- phase AC distributed generation system is proposed for Micro- grid converters. The proposed technique allows even sharing of imbalance current among various converters, can be seamlessly integrated with existing active power-frequency droop control and reactive power-voltage droop control to improve the power quality within the distributed power system. Its control functionalities are discussed, simulation and laboratory test results are also presented to validate the proposed method.
Van doelgroepenbenadering naar business case van diversiteit: de invloed van het kabinet op publieke sectoren

De focus van het diversiteitsbeleid binnen de publieke sector is de afgelopen decennia verschoven. Daar waar in de jaren tachtig het bieden van gelijke kansen voor verschillende doelgroepen centraal stond, veranderde dit na het millennium in het effectief en efficient managen van een divers personeelsbestand voor een beter presterende publieke sector, ook wel de business case van diversiteit genoemd. Dit artikel gaat na in hoeverre het kabinet invloed heeft gehad op het diversiteitsbeleid van publieke organisaties
Creation of a new design management system based on process optimization and proactive strategy

There are numerous designers involved in building design, and the various parties need information from each other as a basis for their design decisions. The design co‐ordinator cannot be an expert on all information needs of every design discipline. The various designers, again, focus on their current work only, and neglect the planning of forthcoming design activities. This results in a lack of information, guess‐work, idling and delays in the self‐steering process. The end result is extensive redesign and problems in the construction stage. This article describes a design management system developed to minimize these problems. The system includes operational systematics to be followed by all the actors involved in the design process. Another part of the solution is a reference model on typical information needs by different designers in various stages and tasks of the design process. The system was developed as part of two actual building design processes.
Synthetic retinoid Am80 ameliorates chronic graft-versus-host disease by downregulating Th1 and Th17

Chronic GVHD (cGVHD) is a main cause of late death and morbidity after alloge-neic hematopoietic cell transplantation, but its pathogenesis remains unclear. We investigated the roles of Th subsets in cGVHD with the use of a well-defined mouse model of cGVHD. In this model, development of cGVHD was associated with up-regulated Th1, Th2, and Th17 responses. Th1 and Th2 responses were up-regulated early after BM transplanta-tion, followed by a subsequent up-regulation of Th17 cells. Significantly greater numbers of Th17 cells were infiltrated in the lung and liver from allogeneic recipients than those from syngeneic recipients. We then evaluated the roles of Th1 and Th17 in cGVHD with the use of IFN-␥– deficient and IL-17–deficient mice as donors. Infusion of IFN-␥ ؊/؊ or IL-17 ؊/؊ T cells attenuated cGVHD in the skin and salivary glands. Am80, a potent synthetic retinoid, regulated both Th1 and Th17 responses as well as TGF-␤ expression in the skin, resulting in an attenuation of cutaneous cGVHD. These results suggest that Th1 and Th17 contribute to the development of cGVHD and that targeting Th1 and Th17 may therefore represent a promising therapeutic strategy for preventing and treating cGVHD. Introduction GVHD is a result of immune attack of host tissues, such as the skin, gut, liver, and lung, by donor T cells in transplants. 1,2 On the basis of the differences in clinical manifestations and histopathology, GVHD can be divided into acute and chronic types. Chronic GVHD (cGVHD) is the main cause of late death and morbidity after allogeneic hematopoietic stem cell transplantation. 3-5 cGVHD often presents with clinical manifestations that resemble those observed in autoimmune diseases, such as systemic lupus erythe-matosus, Sjögren syndrome, lichen planus, and scleroderma. It has traditionally been assumed that the predominant cytokines produced during acute GVHD are Th1 cytokines, whereas those produced during cGVHD are Th2 cytokines. Although recent studies have suggested that cGVHD could be caused by cytokines secreted by Th1 cells, 6 Th17 cells, 7 or autoantibodies, 8 or both, the immune mechanisms leading to the development of cGVHD are not completely understood. Th17 cells are a third subset of polarized effector T cells characterized by their expression of proinflammatory cytokine IL-17 and other cytokines. 9 IL-17 belongs to a family of 6 members: IL-17A, IL-17B, IL-17C, IL-17D, IL-17E (also known as IL-25), and IL-17F. Of these, IL-17A and IL-17F are the best characterized cytokines and form heterodimers. IL-17 plays an …
Eagle Ford Completion Optimization Strategies Using Horizontal Logging Data

Summary Four operators drilling in the Eagle Ford Shale Play located in South Texas, USA joined Schlumberger in an initiative to acquire various types of open hole logging data in several horizontal wells, and then use the data to design the completions with optimum fracture stage and perforation cluster positioning. The wells were then evaluated with horizontal production logs to gauge the effectiveness of using the log data to engineer the completions. This paper will outline the processes used to acquire the data, the analyses made on that data, application, results and conclusion. The study draws on previous work showing perforation cluster contribution variation in several shale plays including the Eagle Ford (Miller, 2011), and other documented results showing the effect of targeting similarly stressed rock for fracture treatments (Waters, 2011). The main objective was to improve the initial flow capacity of the well by increasing the number of perforation clusters contributing to production. Another related objective was to determine the optimal horizontal logging program that was needed to characterize the rock with minimal interruption to existing work flows. This paper will show the results of data acquired over 12 horizontal wells in the Eagle Ford Shale. Petrophysical and geomechanical analyses were based on horizontal logging measurements and used as inputs to an engineered completion design tool that generated a recommendation on each well design. The design tool grouped intervals with similar properties for stimulation treatment. Following the treatment, horizontal production logs were run through the zones to measure the perforation cluster contribution. The results of the study have the potential to change the way Unconventional Resources are developed. Recent trends have seen a shift away from data acquisition to blind geometrical fracturing. This paper examines the value of acquiring petrophysical data in the lateral section and its application to completion optimization, the minimization of wasted resources, and the impact on early production.
5.3 GHz MIMO radio channel sounder

A radiowave propagation measurement system for wideband multichannel multiple-input multiple-output (MIMO) measurements at 5.3 GHz is presented. The MIMO channel matrix of 32 times 32 can be measured using microwave switches at the transmitter (TX) and the receiver (RX). The system is capable of measuring direction-of-departure (DoD) and direction-of-arrival (DoA) with dual polarization in both TX and RX. The antenna configuration can be selected to use planar array or semispherical groups at each end of the link. A high power switch is used at TX to enable large measurement distances. Results from calibration in an anechoic chamber and from measurement campaigns are shown
HIV-related knowledge among people living with HIV/AIDS in Kelantan, Malaysia

ABSTRACT The authors of this cross-sectional study aims to translate and validate the brief HIV Knowledge Questionnaire (HIV-KQ-18) into Malay language, to assess HIV-related knowledge and its sociodemographic predictors among a sample of people living with HIV/AIDS in Kelantan, Malaysia. A total of 160 HIV patients participated in this study. The Malay version of HIV-KQ-18 showed good internal consistency with Cronbach’s α value of . 78. Intraclass correlation coefficient was 0.76 (95% confidence interval, 0.61 to 0.85). The HIV-KQ-18 score was normally distributed with a mean of 9.7 (SD = 3.78). The mean percentage of correct responses was 53.7 (SD = 21.0). Higher education level and longer period of living with HIV were significantly associated with better HIV knowledge. In conclusion, the Malay version of HIV-KQ-18 is a valid and reliable instrument to assess HIV-related knowledge, which was found to be lacking in certain aspects among our sample.
Joint effort to improve quality in a Brazilian public pediatric hospital through cross-infection control

OBJECTIVES: To examine the role of the laboratory in nosocomial infection control from January 1993 to December 1996 in Centro Geral de Pediatria of Hospital Foundation of Minas Gerais state. METHODS: Follow -up of 101,139 patient-days (11,147 discharges + deaths + transfers) in the wards and intensive care unit by using the National Nosocomial Infection Surveillance (NNIS) system proposed by the Centers for Disease Control and Prevention (CDC- Atlanta). Prospective surveillance of nosocomial infections at all sites was performed according to the hospital - wide (since 1992) and intensive care unit (since 1996) NNIS components. The CDC definitions since 1988 and Brazilian Ministry of Health regulation number 930 since 1992 were used to diagnose the nosocomial infections. RESULTS: The five most frequent nosocomial pathogens (from a total of 139 isolates) were Klebsiella sp = 24.5%; S. aureus = 18%; P. aeruginosa = 13.7%; E. coli = 12.9%; S. epidermidis = 12.2%. The percentage of identification of pathogens isolated from nosocomial infection sites has increased from 6.2% in 1993 to 13.3% in 1995 and 28.2% in 1996 (p< 0.001) and so has the attempt to isolate the pathogens: 7.5% in 1993, 16.1% in 1995, 33.8% in 1996 (p< 0.001). The time interval taken for lab results (from specimen collected to microbiology result) has decreased from the average of ten days in 1993 to six days in 1996 (p = 0.001). CONCLUSIONS: The continuing education and improved communication among infection control personnel, pediatricians, surgeons and members of the laboratory have proven to play a key role in the epidemiology of nosocomial infections by defining their etiologies in the Centro Geral de Pediatria. A task force to determine the microbiology has been achieved by the understanding of all clinicians that it is important to treat their patients specifically. The NNIS method applied to Brazilian hospitals has shown its impact on the microbiology lab role in nosocomial infection control as well.