Miracle-dz/UniFAR-FTUs huggingface dataset:
Diagnostic value of serum miR-145 and miR-185 as targeting of the APRIL oncogene in the B-cell chronic lymphocytic leukemia

Background: Chronic lymphocytic leukemia (CLL) is one of the most common hematologic malignancy in adults worldwide. This cancer has a poor prognosis at different stages. So, the identification of new biomarkers is important for early diagnosis of B-CLL. Considering the oncogenic role of APRIL molecule in this leukemia as well as the regulatory role of microRNAs (miRNAs) in different signaling pathways, the present study evaluated the miRNAs targeting APRIL gene in B-CLL.Methods: The miRNAs were predicted and selected using bioinformatics algorithms. A total of 80 plasma samples (40 samples of healthy individuals and 40 samples of B-CLL patients) were subjected to RNA extraction and synthesis of cDNA. The expressions levels of predicted miRNAs and APRIL gene in plasma of B-CLL patients and healthy individuals were assessed by Real time PCR analysis. ROC analysis was performed to investigate the role predicted miRNAs as novel biomarkers in diagnosis of B-CLL. Results: The results of the prediction showed that miR-145-5p and miR-185-5p target the APRIL gene. The expression level of APRIL gene was strikingly higher in plasma of B-CLL patients than in the healthy individuals (102, P= 0.001). On the other hand, expression levels of miR-145-5p and miR-185-5p were strikingly lower in B-CLL patients than in the healthy individuals (0.07, P= 0.001) (0.29, P= 0.001). Also, ROC curve analyses demonstrated that miR-145-5p and miR-185-5p are specific and sensitive and may serve as new biomarkers for the early detection of B-CLL. Conclusions: These data suggest that the study miRNAs may have a role in B-CLL development and progression. Moreover, miR-145-5p and miR-185-5p can be served as a novel and potential biomarker in the diagnosis of B-CLL.
PWM control techniques in current source rectifiers

Force commutated current source rectifiers are mostly controlled using PWM patterns generated offline. This procedure simplifies the inclusion of special requirements associated with unidirectional power switches. This paper shows that online techniques developed for voltage source inverters can be readily adapted to current source rectifiers, thus taking advantage of features such as reduced switching frequency and increased gain. Implementation and performance of the proposed carrier-based and space vector techniques are presented. Finally, the proposed carrier-based techniques are verified an a 5 kVA experimental unit. <<ETX>>
Solar array flight dynamic experiment

The purpose of the Solar Array Flight Dynamic Experiment (SAFDE) is to demonstrate the feasibility of on-orbit measurement and ground processing of large space structures' dynamic characteristics. Test definition or verification provides the dynamic characteristic accuracy required for control systems use. An illumination/measurement system was developed to fly on space shuttle flight STS-41D. The system was designed to dynamically evaluate a large solar array called the Solar Array Flight Experiment (SAFE) that had been scheduled for this flight. The SAFDE system consisted of a set of laser diode illuminators, retroreflective targets, an intelligent star tracker receiver and the associated equipment to power, condition, and record the results. In six tests on STS-41D, data was successfully acquired from 18 retroreflector targets and ground processed, post flight, to define the solar array's dynamic characteristic. The flight experiment proved the viability of on-orbit test definition of large space structures dynamic characteristics. Future large space structures controllability should be greatly enhanced by this capability.
A PLC-Based Tension Training System Design

The PLC-based tension training system consists of three-phase asynchronous motors, programmable logic controllers (PLC), inverters, touch screen and sensor. Taking PLC as the controller, the system uses two sets of three-phase asynchronous motors to complete the delivery and winding of fibers, uses two inverters respectively to control the operation of the motors, and measures the fiber tension through tension sensor, and then feeds back the result to the PLC. Besides, by the touch screen control interface design, the system can achieve single motors inching, winding, and unwinding, two motors simultaneous operation and other operation modes. PID, fuzzy PID, genetic algorithm based PID and other algorithms can be used in the tests of the system. The PLC-based tension training system is of great help for enhancing the hands-on ability of college students or junior technical staff.
Patched Local Lunar Gravity Solutions Using GRAIL Data

We present a method to determine local gravity fields for the Moon using Gravity Recovery and Interior Laboratory (GRAIL) data. We express gravity as gridded gravity anomalies on a sphere, and we estimate adjustments to a background global start model expressed in spherical harmonics. We processed GRAIL Ka‐band range‐rate data with a short‐arc approach, using only data over the area of interest. We determine our gravity solutions using neighbor smoothing constraints. We divided the entire Moon into 12 regions and 2 polar caps, with a resolution of 0.15°×0.15° (which is equivalent to degree and order 1199 in spherical harmonics), and determined the optimal smoothing parameter for each area by comparing localized correlations between gravity and topography for each solution set. Our selected areas share nodes with surrounding areas and they are overlapping. To mitigate boundary effects, we patch the solutions together by symmetrically omitting the boundary parts of overlapping solutions. Our new solution has been iterated, and it has improved correlations with topography when compared to a fully iterated global model. Our method requires fewer resources, and can easily handle regionally varying resolution or constraints. The smooth model describes small‐scale features clearly, and can be used in local studies of the structure of the lunar crust.
School DNA and Its Transfer

This study aims to examine the concept of “organizational DNA” which clarifies the features of an organization and helps to predict about the state of organizations in terms of schools and to bring “DNA transfer” up for discussion. Thus, a descriptive study was conducted with the help of six high school principals. The study was carried out by using maximum variation sampling with the phenomenological pattern. The data were collected through a questionnaire with open-ended questions, interviews and focus group discussions. Descriptive and content analysis methods were used to analyze the data. At the end of the study, four different features regarding the school DNA were defined and it was suggested that rotations, training school principals and leader teachers and replacement of administrators may be effective in transferring school DNA. Normal 0 false false false EN-US X-NONE AR-SA /* Style Definitions */ table.MsoNormalTable {mso-style-name:"Table Normal"; mso-tstyle-rowband-size:0; mso-tstyle-colband-size:0; mso-style-noshow:yes; mso-style-priority:99; mso-style-parent:""; mso-padding-alt:0in 5.4pt 0in 5.4pt; mso-para-margin:0in; mso-para-margin-bottom:. 0001pt; text-align:justify; mso-pagination:widow-orphan; font-size:11.0pt; font-family:"Calibri","sans-serif"; mso-ascii-font-family:Calibri; mso-ascii-theme-font:minor-latin; mso-hansi-font-family:Calibri; mso-hansi-theme-font:minor-latin;}
Novel Process For A Monolithic Integrated Accelerometer

A monolithic sensor, fabricated using a technology that combines surface micromachining with a BiCMOS process, is described. The capacitive sensing element consists of a 10/spl mu/m thick layer of polysilicon that is deposited in an early stage of the IC fabrication sequence. A high degree of synergy is achieved and conflicting issues regarding the merging of the processes are avoided by us ing IC processing steps for manufacturing of the sensor element. Adhesion between parts of the sensor structure, during their release, is eliminated by using an HF vapor phase etching process for the sacrificial layer. The completed sensor has been characterized successfully.
The use of protocol analysis for determining ability requirements for personnel selection on a computer-based task

Abstract The role of cognitively oriented tasks in the workplace continues to increase as automation of physical task components advances. Difficulties in automating the operator's cognitive processes have placed a renewed emphasis on the human component in advanced manufacturing systems. While traditional task analysis techniques have made significant contributions to improving productivity when important task elements are visually observable, their focus on manual task procedures make them less effective for cognitively oriented activities. This research has made a first attempt at integrating techniques from several disciplines to develop a cognitive task analysis methodology. The utility of this combined approach is examined for a new system being tested in the United States Postal Service. This task requires operators to encode, via a keyboard, addresses presented on a video display terminal. Results support the hypothesis that, for cognitively oriented tasks, a consensus based analysis technique (th.
Stickball in San Francisco

STICKBALL IN S A N FRANCISCO STEPHEN J . AGOSTINI, JOHN M . QUIGLEY, AND EUGENE SMOLENSKY This is a simple game: you throw the ball, you hit the ball, you catch the ball. You got it? —Bull Durham On July 11, 1961, one year after opening, San Francisco's Candlestick Park was the site of baseball's thirtieth All-Star Game. The new stadium, built to lure the former New York *mmffi30t Giants to the West Coast, became the stage for a most un­ usual comedy. As the New York Times described it, For eight innings, in the stillness of an unusually hot and almost windless afternoon, bril­ liant National League pitching, starting with Warren Spahn, had held the vaunted American League to just one hit while the senior loop piled up a 3-1 lead. But in the ninth inning, the already infamous Candlestick Point winds picked up. While local fans, knowing full well what was coming, were heading for the exits before being blown into the bay, the National League made three errors, including a comical muff of a pop foul by catcher Smoky Burgess. Finally, with runners on first and second, right-hander Stu Miller was brought in to replace Sandy Koufax. As he wound up for his first pitch, a sudden gust blew Miller off the pitcher's a This chapter received research support from the Koret Foundation. Quigley's research is supported by the Fisher Center for Real Estate and Urban Economics, University of California, Berkeley. We acknowledge the able assistance provided by Sandra Sullivan in archival research and data analysis. The discussion benefited from the comments of Randall Hamilton, Dennis Howard, Roger Noll, and Andrew Zimbalist.
High-Stiffness, Lock-and-Key Heat-Reversible Locator-Snap Systems for the Design for Disassembly

Driven by the moral sense of obligation, legislative and social pressures, manufacturers now consider effective part reuse and material recycling at the end of product life at the design stage. It is a key consideration to use joints that can disengage with minimum labor, part damage, and material contamination. This paper extends our previous work on the design of high-stiffness reversible locator-snap system that can disengage nonde-structively with localized heat (Shalaby and Saitou, 2006, "Optimal Heat-Reversible Snap Joints for Frame-Panel Assembly in Aluminum Space Frame Automotive Bodies," Proceedings of the LCE2006: The 13th CIRP International Conference on Life Cycle Engineering, Leuven, Belgium, May 31-Jun. 2, pp. 411-416; Shalaby and Saitou, 2008, "Design for Disassembly With High-Stiffness, Heat-Reversible Locator-Snap Systems," ASME J. Mech. Des., 130(12), p. 121701) to include (1) modeling for tolerance stack-up and (2) lock-and-key concept to ensure that snaps only disengage when the right procedure is followed. The design problem is posed as an optimization problem to find the locations, numbers, and orientations of locators and snaps, and the locations and sizes of heating areas, to release the snaps with minimum heat, compliance, and tolerance stack-up. The motion and structural requirements are considered constraints. Screw theory is employed to precalculate the set of feasible types and orientations of locators and snaps that are examined during optimization. Multi-objective genetic algorithm coupled with structural and thermal finite element analysis is used to solve the optimization problem. The method is applied on two case studies. The Pareto-optimal solutions present alternative designs with different trade-offs between the design objectives.
Slow‐wave characteristics of a 1D EBG structure for a miniaturized monopole antenna

Transmission line and monopole antenna embedded with one‐dimensional electromagnetic bandgap (1D EBG) structure were designed, fabricated, and characterized. The slow wave characteristics of a 1D EBG cell were verified using an electro‐optic near‐field mapping system. The group velocity of the electric pulse propagating along the coplanar waveguides loaded with the 1D EBG cell was effectively slowed down compared with that of the pulse propagating along the normal coplanar waveguide without a 1D EBG cell. The slow wave characteristics were utilized to reduce the size of the monopole antenna. A compact monopole antenna could be designed by incorporating a 1D EBG cell on the radiator of the antenna. The fabricated 1D EBG monopole antenna exhibited a 58% reduction in size and performance that was comparable to a large reference monopole antenna. © 2009 Wiley Periodicals, Inc. Microwave Opt Technol Lett 51: 1231–1235, 2009; Published online in Wiley InterScience (www.interscience.wiley.com). DOI 10.1002/mop.24284
Optical wavelet packet transform and best basis selecting by a volume holographic opto-electronic hybrid system

Wavelet packet transform analyzes signals more finely than wavelet transform does. This advantage can be utilized in optical wavelet transform. To introduce wavelet packet transform into optics, mother wavelets that have scaling functions must be used. If the scaling function does not have analytical formula, its approximation can be computed using the cascade algorithm. With the refinement relationship, its wavelet function can by calculated. After the 1-D wavelet packet bases are obtained, 2-D separable wavelet packet bases can be constructed for optical wavelet packet transform. As an example, a volume holographic opto-electronic system is proposed to fulfill joint best basis selection for a face image bank with the mother Db3.
Experimental investigation of an adjustable ejector for CO2 heat pump water heaters

An adjustable ejector expansion device for a CO2 heat pump water heater (HPWP) is proposed to improve the system performance. It has been designed to investigate experimentally the effects of the motive nozzle throat area of the ejector, entrained flow pressure, back pressure and primary flow pressure on the entrainment ratio. Experiments based on different motive nozzle throat areas were conducted and the results of the prototype ejector using CO2 as working fluid are presented. The results show that an adjustable ejector can achieve high performance and work well in a wide range of working conditions.
Exploiting the potential

States that industrial design has in the past emphasized styling and tended to ignore the importance of satisfying consumer needs. Suggests companies should learn to cultivate designers′ skills by integrating industrial designers from early on in the process, harnessing the full potential of industrial design. Indicates that most Western companies have poor product design management. Suggests that one way to help improve both integration and design management would be through extra postgraduate education.
Physically based morphostructural land surface segmentation: Case of the Alps and Western Carpathians

The presented morphostructural segmentation of the Alps and Western Carpathians uses physically based geomorphometric variables as input data and object‐based image analysis as a procedure to delineate objects of interest. A previous suitability evaluation of simple object‐based methodology showed its potential in recognition of morphostructural features. When segmenting the Western Carpathians, we moved towards a more specific object‐based approach—a fusion of segmentation and classification at several hierarchical levels. Such an approach was evaluated as not necessary in the less contrasting terrain in the Alps, where only a simple segmentation was used for evaluation of its efficiency. Use of physically based geomorphometric variables as input data brought enhancement of subsequent morphotectonic interpretations. After the segmentations, an index of steady state (ISS) for the entire object levels and their parts was computed. This ISS was used to evaluate and compare the two study areas in terms of their geodynamic development. Similarities and differences in development of these relatively alike mountain ranges are interpreted.
Compressive sensing imaging through a drywall barrier at sub-THz and THz frequencies in transmission and reflection modes

In this work sub-terahertz imaging using Compressive Sensing (CS) techniques for targets placed behind a visibly opaque barrier is demonstrated both experimentally and theoretically. Using a multiplied Schottky diode based millimeter wave source working at 118 GHz, metal cutout targets were illuminated in both reflection and transmission configurations with and without barriers which were made out of drywall. In both modes the image is spatially discretized using laser machined, 10 × 10 pixel metal apertures to demonstrate the technique of compressive sensing. The images were collected by modulating the source and measuring the transmitted flux through the apertures using a Golay cell. Experimental results were compared to simulations of the expected transmission through the metal apertures. Image quality decreases as expected when going from the non-obscured transmission case to the obscured transmission case and finally to the obscured reflection case. However, in all instances the image appears below the Nyquist rate which demonstrates that this technique is a viable option for Through the Wall Reflection Imaging (TWRI) applications.
FBG Sensing Demodulation Technology Based on Acousto-Optic Tunable Filter

This paper describes FBG sensing demodulation technology which based on acousto-optic tunable filter, this technique solves the traditional FBG demodulation technique existing some problems such as slow demodulation speed and small number of driving FBG sensors. The demodulation technique has advantages with simple structure, low cost, wide wavelength range, high resolution and fast demodulation speed.
Deep learning based automated detection of intraretinal cystoid fluid

The diversified ocular disorders in which cystoid macular edema (CME) occurs, are strongly associated with the vision loss. Optical coherence tomography (OCT) scans that allow screening of the retina, contain artifacts including blur‐edges, speckle noise, and so forth, which create difficulty in identifying retinal fluid. In this work, major image preprocessing techniques such as minimum filtering, block‐matching and 3D filtering, and Richardson–Lucy deconvolution method are applied to minimize noise and other degradation effects from OCT scans, ensured by maintaining image quality assessment scores, that is, blind‐less image spatial quality evaluator and sharpness estimation score. Furthermore, this work develops an automated method based on deep learning (DL) to detect the presence and progression of retinal fluid, that is, CME and its quantification. Specifically, U‐net model with efficient tuning of hyperparameters is proposed to obtain optimal results. The algorithm's performance is evaluated for accurate identification of fluid localization in the case of diabetic macular edema (DME), having CME regions, and compared against the manual segmentation of fluid by experts, which are highly correlated. This enhanced DL method achieves better performance than the algorithms previously reported. The proposed algorithm is evaluated on several performance metrics during training and reports the best score of 99.81, 0.50, 83.34, 86.56, 80.89, and 99.48% for model accuracy, binary cross‐entropy loss, Dice coefficient (DC), precision, recall, and area under the ROC‐curve, respectively. Additionally, fourfold cross‐validation technique is also applied and an average DC score of 84.00% is obtained. This approach can be helpful to prevent vision loss.
Design of the Assistive Leg and the Simulation Research

The wearable assistive leg is a kind of traditional exoskeleton device, which not only can help healthy people with walking, but also can assist those who have walking troubles to rehabilitate. Based on the bionics principle and the research on the body mechanism, a wearable assistive leg for rehabilitation training and power augmentation is designed. This device satisfies the requirement of the compact structure, portability and safety. Then the dynamic model of the assistive leg is constructed based on the Lagrange theory. The mechanical structure is devised by Solidworks2011 software in which a standard human body model and this assistive leg are assembled. Thus the assembly is introduced into Adams2007 R3. The dynamics simulation is carried in this software. The results and the existing problems are analyzed. The simulation results show that this kind of assistive leg can provide helping force for human lower extremity movements.
Effect of Some Preliminary Processing Techniques on Nutrients, Anti-nutrients, Mineral and Vitamin Composition of Four Varieties of Nigerian Sweet Potato [Ipomoea Batatas L. (Lam.)]

ABSTRACT Effects of preliminary processing techniques such as peeling, washing, cutting, slicing and drying on chemical composition of sweet potato were studied. Generally there were increases in protein, fat, carbohydrates, ash, fiber and sugars. Calcium, potassium and magnesium contents were increased in all samples. Iron contents were increased as much as 37% to 88%, zinc 7% to 9%, copper 252% to 333%. Vitamin C contents were reduced by 46% and 52%. Thiamine contents increased by between 14% and 100%. Riboflavin and Niacin were greatly increased for all samples. β-carotene contents were increased between 17% and 72%. Tannin was the only anti-nutrient found. It was observed to have reduced in all samples between 66% and 70%. The results of this study may help in understanding changes in nutrition during preliminary processing and therefore preservation of food quality. Abbreviations: Orange fleshed sweet potato (OFSP); Purple fleshed sweet potato (PFSP); Yellow fleshed sweet potato (YFSP); White fleshed sweet potato (WFSP); Association of Official Analytical Chemists (AOAC); Trypsin Inhibition Activity (TIA); Analysis of Variance (ANOVA); Statistical Packages for Social Sciences (SPSS); Duncan’s Multiple Range Test (DMRT); International Union of Food Science and Technology (IUFosT); United States Potato Board (USPB), ND (Not Detected).