Miracle-dz/UniFAR-FTUs huggingface dataset:
Interleukin-1-induced Nuclear Factor-κB-IκBα Autoregulatory Feedback Loop in Hepatocytes

The IκB inhibitors regulate the activity of the potent transcription factor nuclear factor-κB (NF-κB). Following signal-induced IκB proteolysis, NF-κB translocates into the nucleus to activate transcription of target genes, including IκBα itself, initiating the “NF-κB-IκBα autoregulatory feedback loop. ” Upon IκBα resynthesis, NF-κB is subsequently inactivated and redistributed back into the cytoplasm. We have previously reported a robust NF-κB-IκBα autoregulatory feedback loop in HepG2 hepatocytes. Sixty minutes after tumor necrosis factor (TNF-α) stimulation, IκBα is resynthesized to ∼2-fold greater level than in control cells and completely inhibits NF-κB binding. Here we investigate the mechanism for IκBα resynthesis comparing the effect of stimulation of TNF-α with that of interleukin-1 (IL-1α). Although either TNF-α or IL-1α stimulation of protein kinase C (PKC)-down-regulated cells equivalently induces NF-κB translocation, the kinetics of IκBα resynthesis is slowed. Moreover, pretreatment with selective calcium-dependent PKC inhibitors selectively slowed the kinetics of the IL-1α-induced overshoot without affecting that produced by TNF-α. Down-regulation of PKCα by antisense phosphorothioate oligonucleotides and expression vectors selectively blocked the IL-1α-induced IκBα overshoot. In the absence of PKCα, although IL-1α induced similar amounts of IκBα transcription and changes in steady-state mRNA, a greater component of IκBα mRNA was retained in the nucleus. These data indicate a selective role for PKCα in IL-1α-induced IκBα resynthesis, which is mediated, at least in part, by post-transcriptional control of mRNA export.
ON NANOFLUIDS-PART II : EXPERIMENTS AND APPLICATIONS

Research in convective heat transfer using suspensions of nanometer-sized solid particles in base liquids started only over the past decade. Recent investigations on nanofluids, as such suspensions are often called, indicate that the suspended nanoparticles markedly change the transport properties and heat transfer characteristics of the suspension. This second part of the review covers fluid flow and heat transfer characteristics of nanofluids in forced and free convection flows and potential applications of nanofluids. Opportunities for future research are identified as well.
Analysis of the Veracities of Industry Used Software Development Life Cycle Methodologies

Currently, software industries are using different SDLC (software development life cycle) models which are designed for specific purposes. The use of technology is booming in every perspective of life and the software behind the technology plays an enormous role. As the technical complexities are increasing, successful development of software solely depends on the proper management of development processes. So, it is inevitable to introduce improved methodologies in the industry so that modern human centred software applications development can be managed and delivered to the user successfully. So, in this paper, we have explored the facts of different SDLC models and perform their comparative analysis.
Development of a polymerase chain reaction and its comparison with agar gel immunodiffusion test in the detection of bovine leukemia virus infection

A reacao em cadeia pela polimerase (PCR) foi utilizada para a deteccao do virus da leucemia bovina (VLB) em leucocitos perifericos de bovinos infectados. Os iniciadores utilizados foram construidos para amplificar uma parte do gene env do VLB. Os produtos da PCR foram analisados por eletroforese em gel de agarose corados por brometo de etideo. A especificidade analitica da PCR foi confirmada por restricao enzimatica dos produtos da reacao com Bam HI e tambem pela analise da sequencia de tres amostras. Sessenta e cinco animais foram testados para a presenca de anticorpos anti-VLB, pela imunodifusao em gel de agar (IDGA) e pela PCR, para deteccao direta do VLB. Houve 73,80% de concordância entre os dois testes. Quatro animais positivos na IDGA foram PCR negativos, enquanto 13 animais negativos na IDGA foram positivos na PCR. A sensibilidade diagnostica obtida foi de 0,87 e a especificidade diagnostica 0,62. A PCR desenvolvida pode ser uma ferramenta complementar no diagnostico de infeccoes causadas pelo VLB, mas deve ter sua sensibilidade diagnostica melhorada.
Comparison of full-model and reduced-model EKF based position and speed estimators for sensorless DTC of permanent magnet synchronous machines

The aim of this paper is to study the use of the Extended Kalman filer (EKF) for sensorless control of a permanent magnet synchronous motor (PMSM) drive controlled by direct torque control (DTC). The main drawback of DTC is the necessity of short sampling period. The challenge for the EKF is therefore the minimization of its execution time. This is achieved by using so called reduced state space model of the drive with only two state variables, the rotor speed and the rotor position. It is proved by simulations and experiments that the EKF with this reduced model has the same performance as the four-dimensional full state space model at much lower computational cost. The sensorless DTC with the reduced model EKF was found to be equal to DTC with the full model EKF in terms of performance and superior in terms of computational cost. All experiments were carried out on a laboratory prototype of the drive with rated power of 250 W.
Do Consumers Perceive Precise Prices to be Lower than Round Prices? Evidence from Laboratory and Market Data

We examine two questions: Does precision or roundedness of prices bias magnitude judgments? If so, do these biased judgments affect buyer behavior? In a laboratory pre-test, we find that people incorrectly judge precise prices (e.g., $325,425) to be lower than round prices of similar magnitudes (e.g., $325,000). Building on evidence of greater prevalence of precision in smaller numbers and roundedness in larger numbers (Dehaene and Mehler 1992), we suggest that representativeness of digit patterns might influence magnitude judgments. We term this the precision heuristic in price magnitude judgments. We examine the effect of this precision heuristic on buyer's willingness to pay (WTP) in two distinct but complementary ways. First, we conduct a laboratory study to understand the psychological mechanism behind the precision heuristic. We find that people do learn to associate precision with smaller magnitudes, and that this association biases their price magnitude judgments. Additionally, we rule out alternative explanations which posit that a precise price signals a seller's low-price strategy or her unwillingness to negotiate. Based on these findings, we suggest that although the precision heuristic can lead to biased judgments, it is an ecologically valid judgment criterion. Next, using data from more than 27,000 residential real estate transactions in two separate markets, we find that buyers pay higher sale prices when list prices are more precise. This finding is consistent with the precision heuristic, suggesting that buyers perceive precise list prices to be lower, and therefore accept sale prices that are closer to the list price. These results have substantive implications for buyer and seller behaviors, and theoretical implications for the understanding of price cognition process.
Reduction in Shottky barrier height of AlGaN-based SBD with in-situ deposited silicon carbon nitride (SiCN) cap layer

AlGaN/GaN Schottky barrier diodes (SBDs) with and without in-situ silicon carbon nitride (SiCN) cap layer were investigated. The fabricated SBD with SiCN cap layer exhibited improved electrical characteristics, such as the forward turn on voltage of about 0.7 V, the forward current of 4.1 A at 1.5 V, and the reverse breakdown voltage of 630 V, compared to the corresponding values of 0.8 V, 3.8 A, and 580 V for the reference SBD without the SiCN cap layer. This improvement in the device performance of the SiCN-SBD is because the in-situ SiCN cap layer not only lowers the barrier height, but also effectively passivates the surface of the device with better surface morphology.
MODELLING AND STIMULATION OF TARGET TRACKING AND LOCALIZATION IN WIRELESS SENSOR NETWORK

Original scientific paper Localization and tracking of moving target is one of the research focuses of wireless sensor network applications. It has great value in military field. Researchers have proposed many algorithms to complete target localization precisely. Tri-cyclic mutual crosses method based on received signal strength indicator can skip the estimation of transmitting attenuation consumption to locate the target accurately. For the great error happening when the target turns its direction, this paper proposes an algorithm to predict the turning point of its motion path. This method can improve the approximation between depicted and real trajectory, and promote the localization and tracking accuracy of whole system.
An Investigation of Social Support and Burnout among Special Education Teachers in the United Arab Emirates.

This study aimed at investigating which source of social support (supervisors, colleagues, friends, spouse, or family) would be most effective in reducing burnout among special education teachers. A sample of 300 special education teachers (50 males and 250 females) completed Burnout and Sources of Social Support questionnaires. Pearson correlation coefficients and ANOVA procedures were utilized to analyze the data. Results revealed significant positive correlations between family support, colleagues support, and personal accomplishment. Demographic variables sex, age, marital status, and teaching experience were not significantly related to any of the three burnout dimensions. Results were interpreted and implications for special education teachers were suggested. The United Arab Emirates (UAE) is comprised of seven emirates. It is situated on the Arabian Gulf, east of Saudi Arabia and north of Oman. The economy is driven by oil and gas and recently tourism. There is a large expatriate population in the country. In 1951, the Trucial States Council was formed, bringing all the leaders of the various groups throughout the region together. In 1971 the formal joining of the seven emirates (Abu Dhabi, Dubai, Sharjah, Ras Al-Kahaimah, Umm Al Qaiwain, and Ajman) was completed in Dubai. There are no political parties or elections since the country is ruled by appointed families established with the formation of the UAE. The Education System in United Arab Emirates The United Arab Emirates Ministry of Education and Youth is responsible for both the public and the private education systems that operate within the country's seven emirates. For the public school system, the Ministry of Education and Youth assumes a broad set of roles, similar to Ministries of Education in other countries. It builds new buildings, hires staff, determines the standards of education, and provides curricular materials and support. The Ministry also coordinates a variety of educationally relevant activities and ensures that adequate programs are operating. On the other hand, the roles of the Ministry of Education and Youth with the private education system are mainly concerned with licensure and supervision. The Ministry ensures that the basic requirements for the physical components of schools are met and that the private schools provide sound educational programs (Bradshaw, Tennant, & Lydiatt, 2004).
Performance Study of Multiple Source Video Streaming via Wireless 5.8 GHz for Intelligent Traffic Management System

This paper describes the performance evaluation on the multiple video source capture and streaming software (multiple-VSCS) developed for the intelligent traffic management system. Motion images captured from multiple independent capture devices are compressed and streamed to a remote location via the 5.8 GHz wireless LAN network. The compression algorithm used here is the current ITU H.263 codec. Performance evaluation tests measured the compressed video stream rate at an average of 500 kbps with total bandwidth utilization at 1.02 %. The performance evaluation will also include measurements of video transfer rates, compression ratio rates with comparison to theoretical ratios. Projections are also made with correlation to increased video transfer rates from multiple sources at different compression formats
Effect of Honey Bee Venom (Apis mellifera) on Hyperglycemia and Hyperlipidemia in Alloxan Induced Diabetic Rabbits

Introduction: In diabetes therapy, a great attention is paid on lowering blood glucose levels and lipid regulating mechanisms of various medical agents including animal toxins. Honey bee venom reduces blood glucose level through increased insulin secretion and glucose take-up. It also has lipid regulating activity verified in several other studies. For that reason, bee venom could be considered as a potential remedy for diabetes. This study aims to investigate the effect of Mongolian honey bee venom on hyperglycemia and hyperlipidemia in alloxan induced diabetic rabbits. Material and method: Twenty two Chinchilla rabbits were divided into three groups: the control (n=6), the diabetic (n=8), and the bee venom treated (n=8) groups. The diabetic group was injected with a 5% solution of Alloxan monohydrate at100 mg/kg intravenously via the marginal vein behind the ear for 2 minutes to induce the diabetes. The bee venom treated group received a bee sting (a sting contains 0.2-0.5 ml of bee venom) on their hind paw every other day after the confirmation of diabetes. Result: Bee venom treatment (BVT) led to the following changes: compared to the diabetic group, the bee venom treated group’s blood glucose levels decreased by 14.9% -26.5%; blood cholesterol levels reduced by 12.5%- 19.1%; Low Density Lipoproteins (LDL) levels lowered by 11.2%-14.2%; and High Density Lipoproteins (HDL) levels increased by 2.5% - 26.25%. Conclusion: Bee venom lowers blood glucose levels and improves lipid profile in alloxan-induced diabetic rabbits and can be considered as a therapeutic agent for diabetes. Further studies should be carried out to determine the most appropriate bee venom dose for the best therapeutic effect.
A novel compact ultra-wideband bandpass filter using dumbbell stubs

In this paper, a compact ultra-wideband (UWB) bandpass filter (BPF) is presented. The proposed filter is constructed with multiple-mode resonator (MMR) and novel dumbbell stubs. The MMR consists of three pairs of shunt dumbbell stubs and a high impedance microstrip line. By modifying the dimensions of the dumbbell stubs, the resonant modes of MMR are allocated in the UWB band with a wide and deep upper-stopband in 13.0–20.0 GHz. The compact UWB BPF is fabricated. Both simulated and measured results show a good agreement.
MLE in presence of equality and inequality nonlinear constraints for the ballistic target problem

This paper focuses on the estimation of the impact point of a ballistic target by means of a batch processing approach which can be applied more specifically when the number of radar measurements is poor. In particular, the maximum likelihood (ML) estimator is proposed for the estimation of the ballistic target trajectory approximated to a pure parabolic curve; also the Cramer-Rao lower bound (CRLB), which gives the minimum theoretically achievable variance of the estimate, is calculated. The estimator accuracy is improved by the application of equality and inequality constraints on the trajectory characteristics such as maximum range, maximum height and trajectory plane. In the case of application of equality constraints also the CRLB can be computed and the constrained estimator improves strongly its accuracy. In real operational scenarios, a smoothed information can be expressed by means of inequality constraints. The performance of the corresponding estimator has been analyzed by means of Monte Carlo simulation, because of the unavailability of computation of the CRLB for this case.
Electric City Bus Energy Flow Model and Its Validation by Dynamometer Test

Battery electric city bus model has been created and the simulation results compared against the measured results from the full scale city bus developed for heavy vehicle research. The model utilizes multi- physics modelling approach with multiple-domains from friction-tyre and transmission model to electrical drive and a simplified battery model. The modelled and measured motor torque, current and voltages in the battery and inverter and the bus speed were compared under a driving cycle based on a local bus line. The simulated results were in good agreement with the experimental measured results; the error between the simulated and measured energy consumption was 1.4 %. The measured average energy consumption was 0.581 kWh/km while the simulation estimated 0.589 kWh/km.
Fuzzy Controller Design for Atomic Force Microscope System

This paper presents the design of a nonlinear rule based fuzzy logic controller for the nonlinear dynamic behavior of the probe tip of an atomic force microscope system (AFMs). At first, we use the bifurcation diagram to analysis the complex dynamic behavior of the atomic force microscope system. Next, the positive maximum Lyapunov exponent is obtained to identify that the chaotic motion do exist in AFMs. In order to suppress the undesired chaotic motion in AFMs, we address the design schemes of fuzzy logic controller to stabilize the slave chaotic AFMs to the master periodic AFMs. In the controller design process, it directly constructs the fuzzy rules subject to a common Lyapunov function such that the error dynamics of master and slave AFMs satisfy stability in the Lyapunov sense. It overcomes the trial-and-error tuning for the membership functions and rule base in traditional fuzzy logic control. Finally, a numerical simulation is used to illustrate the effectiveness of the proposed controller.
A Filtering Approach for Merging Transformer High-Frequency Models With 50/60-Hz Low-Frequency Models

Black-box transformer high-frequency models can be determined via frequency sweep measurements and curve fitting based on rational functions. This procedure often leads to unacceptable model behaviors around 50/60 Hz, making it hard to properly initialize the model for high-frequency transient events. In this paper, we overcome the accuracy problem by merging the frequency sweep data with a data set calculated from a standard 50/60-Hz model. The merging is performed using low-order filters, ensuring a smooth transition between the data sets. The resulting data set is subjected to model extraction via curve fitting and passivity enforcement. The modeling procedure is demonstrated for a 300-kVA distribution transformer. The model is applied in an example of circuit-breaker transient recovery voltage (TRV) simulation, requiring good accuracy at both 50 Hz and at high frequencies.
Chapter 2 Sentiment Analysis Using Social Multimedia

Sentiment analysis is one of the most active research areas in natural language processing, web/social network mining, and text/multimedia data mining. The growing importance of sentiment analysis coincides with the popularity of social network platforms, such as Facebook, Twitter, and Flickr, which provide a rich repository of people’s opinion and sentiment about a vast spectrum of topics. Moreover, the fact that we are exposed to a tremendous amount of data in different forms including text, images, and videos makes sentiment analysis a very challenging task due to its nature of multimodality. In this chapter, in order to provide a big picture of sentiment analysis, we will discuss some of the latest works on topics of sentiment analysis based on visual content and textual content.
Towards Assessing Communicative Competence Using Multimodal Learning Analytics

Multimodal Learning Analytics (MLA) technology has received increasing attention in the learning science field. Recently, novel types of assessments using MLA to analyze the process of student activities have been advocated. In this paper, we suggest an extension of MLA to educational assessments measuring communicative competence. MLA is useful for the measurement of all aspects of the human communication process, e.g., verbal and nonverbal behaviors. Also, MLA’s capability to track rich observations over a long time provides a means to conduct detailed analyses of the human communication process. To support this view, we conducted a brief but informative survey of related research from several areas. Then, we proposed a conceptual framework related to developing new assessments using MLA. One examplary case study was presented to illustrate this framework.
Fly Ormia Ochracea Inspired MEMS Directional Microphone: A Review

Since the discovery of the ears of Ormia ochracea, a parasitic fly, a significant work in designing a microelectromechanical (MEMS)-based directional microphone and its potential applications in medical device, hearing aids, has been carried out. In this paper, we first report the anatomical and behavioral studies of the fly’s ear system and fly’s quest for host finding, respectively. We then give a brief history of the microphones inspired from the fly’s ear anatomy, starting from the beginning when the first time biomechanics of the fly’s ear was reported by Miles group in 1995. Finally, the most demanded application of the MEMS directional microphone, hearing aids, is also reported along with the insight of current challenges and future perspective of the directional microphones.
Synthesis, Crystal Structure and Antimicrobial Activity of (E)-ethyl-4-(2-oxoacenaphthylen-1(2H)-ylideneamino) benzoate

A Schiff base, (E)-ethyl-4-(2-oxoacenaphthylen-1(2H)-ylideneamino)benzoate, (E4AB) had been synthesized in good yield by the acid-catalyzed condensation reaction of acenaphthenequinone and ethyl-4-aminobenzoate in methanolic solution. The synthesized compound was elucidated by elemental analysis (CHN), FTIR, 1H-NMR, 13C-NMR and single crystal X-ray diffraction. E4AB crystallized in the monoclinic crystal system with space group P21/c, Z = 4, V = 1569.3(2) ? 3 and unit cell parameters a = 9.1589(8) , b = 21.2003(17)? , c =8.4502(7) ? , β= 106.972(2)°. The crystal structure of the compound is stabilized by intermolecular C-H···O hydrogen bonds and weak intermolecular π···π interactions. The title compound had been tested for the antimicrobial activity against Bacillus subtilis (B. subtilis), Enterobacter and Fusarium oxysporum f. sp. Cubense (Foc) by disc-diffusion method. E4AB is relatively active against Foc which is a pathogen that cause Wilt disease (also well known as Panama disease) in banana plantation.
Automated Test Equipment for High Power Solid State Device Development and Characterization

This paper describes an automated High Power Amplifier Test System (HPATS) specially designed for tuning, testing and characterization of high power solid state devices during their development. In the 1.0 to 17.0 GHz bandwidth, Si Bipolar, Si MOSFET and GaAs FET transistors with output power up to 150 W for the lower end and up to 25 W for the higher end of the band can be tested. The system has a one-octave instantaneous bandwidth and can operate from 1.0 GHz to 17.0 GHz in four different bands. The base of this equipment, which is low power, covers a 0.5 to 20.0 GHz band, while each of the associated power sections that deliver the input power to the device under test, covers a one-octave bandwidth. For tuning purposes, the Input Return Loss and the Gain versus frequency can be seen in real time. The measurement capabilities of this system include a one-tone test in three modes and a two-tone test in two modes. The one-tone test includes the standard power measurements (Pin, Pout, Gain, Gss, Gain Compression, Phase, Currents, Drain/Collector Efficiency and Power-Added Efficiency) as well as the transmission phase. The two equal tone test includes the measurement of IMD3, IMD5 and IMD7. GaAs FET devices can be biased automatically and the other devices are biased manually. This presentation describes the equipment and exemplifies its capabilities by showing actual data obtained from the measurement of S-band 30 W GaAs FET devices.