Miracle-dz/UniFAR-FTUs huggingface dataset:
Impact of electrode materials on the performance of amorphous IGZO thin-film transistors

This study reports on the fabrication and characterization of thin-film transistors (TFTs) based on indium–gallium–zinc–oxide (IGZO) with various source- and drain-region metals (Pt, W and Ti). The performance of the IGZO transistors is compared to TFTs based on hydrogenated amorphous silicon (a-Si:H) with Pt source- and drain-regions. From the output characteristics maximum saturation mobilities of µ = 0.45 cm^2/Vs for a-Si:H, and µ = 24 to 50 cm^2/Vs for IGZO TFTs are extracted, which are competitive to high-performance thin-film transistors. The study reveals a general influence of the source- and drain-electrode material on the maximum saturation mobility and inverse sub-threshold slope. Graphical abstract
De Novo Transcriptome Sequencing and Analysis of Differential Gene Expression among Various Stages of Tail Regeneration in Hemidactylus flaviviridis

Across the animal kingdom, lizards are the only amniotes capable of regenerating their lost tail through epimorphosis. Of the many reptiles, the northern house gecko, Hemidactylus flaviviridis, is an excellent model system that is used for understanding the mechanism of epimorphic regeneration. A stage-specific transcriptome profile was generated in the current study following an autotomized tail with the HiSeq2500 platform. The reads obtained from de novo sequencing were filtered and high-quality reads were considered for gene ontology (GO) annotation and pathway analysis. Millions of reads were recorded for each stage upon de novo assembly. Up and down-regulated transcripts were categorized for early blastema (EBL), blastema (BL) and differentiation (DF) stages compared to the normal tail (NT) by differential gene expression analysis. The transcripts from developmentally significant pathways such as FGF, Wnt, Shh and TGF-β/BMP were present during tail regeneration. Additionally, differential expression of transcripts was recorded from biological processes, namely inflammation, cell proliferation, apoptosis and cell migration. Overall, the study reveals the stage-wise transcriptome analysis in conjunction with cellular processes as well as molecular signaling pathways during lizard tail regeneration. The knowledge obtained from the data can be extrapolated to configure regenerative responses in other amniotes, including humans, upon loss of a complex organ.
Apartment law in Malaysia buying properties without title: Legal point of view

Strata titles type of property has given rise to many affecting problems affecting all parties interested in dealings with it as to the development, financing and ownership of subdivided buildings. The issue that had arisen has become an issue of great urgency in lieu of the legal transaction to transfer the ownership for strata title properties. The existing laws have many loopholes and not handy when problems come along. The amendments propose only for the problem in relation to management and maintenance of the buildings as well as the further interpretation of the property itself. There are no guideline as to the procedures in conveyancing. The conveyancing practice and procedures adopted by most solicitors to transfer this type of property is insufficient to cater problems that arise in many cases. The existing practiced must be reviewed by the Bar Council to put the laws and the development at the same pace. However there are still so many question left unanswered pertaining to the purchase of the property, to finance the property , to complete the construction of the property and to the solicitor, as to how to expediate the transaction. This paper will give the explaination as to why the problems were created during the transfer of the ownership and to whom do they reflect.
Visual Relationship-Based Identification of Key Construction Scenes on Highway Bridges

Highway bridges play an important role in traffic construction; however, accidents caused by bridge construction occur frequently, resulting in significant loss of life and property. The identification of bridge construction scenes not only keeps track of the construction progress, but also enables real-time monitoring of the construction process and the timely detection of safety hazards. This paper proposes a deep learning method in artificial intelligence (AI) for identifying key construction scenes of highway bridges based on visual relationships. First, based on the analysis of bridge construction characteristics and construction process, five key construction scenes are selected. Then, by studying the underlying features of the five scenes, a construction scene identification feature information table is built, and construction scene identification rules are formulated. Afterward, a bridge key construction scene identification model (CSIN) is built; this model comprises target detection, visual relationship extraction, semantic conversion, scene information fusion, and identification results output. Finally, the effectiveness of the proposed method is verified experimentally. The results show that the proposed method can effectively identify key construction scenes for highway bridges with an accuracy rate of 94%, and enable the remote intelligent monitoring of highway bridge construction processes to ensure that projects are carried out safely.
Highlighting Recent Crystalline Engineering Aspects of Luminescent Coordination Polymers Based on F-Elements and Ditopic Aliphatic Ligands

Three principal factors may influence the final structure of coordination polymers (CPs): (i) the nature of the ligand, (ii) the type and coordination number of the metal center, and (iii) the reaction conditions. Further, flexible carboxylate aliphatic ligands have been widely employed as building blocks for designing and synthesizing CPs, resulting in a diverse array of materials with exciting architectures, porosities, dimensionalities, and topologies as well as an increasing number of properties and applications. These ligands show different structural features, such as torsion angles, carbon backbone number, and coordination modes, which affect the desired products and so enable the generation of polymorphs or crystalline phases. Additionally, due to their large coordination numbers, using 4f and 5f metals as coordination centers combined with aliphatic ligands increases the possibility of obtaining different crystal phases. Additionally, by varying the synthetic conditions, we may control the production of a specific solid phase by understanding the thermodynamic and kinetic factors that influence the self-assembly process. This revision highlights the relationship between the structural variety of CPs based on flexible carboxylate aliphatic ligands and f-elements (lanthanide and actinides) and their outstanding luminescent properties such as solid-state emissions, sensing, and photocatalysis. In this sense, we present a structural analysis of the CPs reported with the oxalate ligand, as the one rigid ligand of the family, and other flexible dicarboxylate linkers with –CH2– spacers. Additionally, the nature of the luminescence properties of the 4f or 5f-CPs is analyzed, and finally, we present a novel set of CPs using a glutarate-derived ligand and samarium, with the formula [2,2′-bipyH][Sm(HFG)2 (2,2′-bipy) (H2O)2]•(2,2′-bipy) (α-Sm) and [2,2′-bipyH][Sm(HFG)2 (2,2′-bipy) (H2O)2] (β-Sm).
Plant propagation algorithm for integration of distributed generation in power systems

Purpose The purpose of this study/paper is to integrate distributed generation optimally in power system using plant propagation algorithm. Distributed generation is a growing concept in the field of electricity generation. It mainly comprises small generation units installed at calculated points of a power system network. The challenge of optimal allocation and sizing of DG is of utmost importance. Design/methodology/approach Plant propagation algorithm and particle swarm optimisation techniques have been implemented where a weighting factor-based multi-objective function is minimised. The objective is to cut down real losses and to improve the voltage profile of the system. Findings The results obtained using plant propagation algorithm technique for IEEE 33-bus systems are compared to those attained using particle swarm optimisation technique. The paper deals with the optimisation of weighting factor-based objective function, which counterpoises the losses and improves the voltage profile of the system and, therefore, helps to deliver the best outcomes. Originality/value This paper fulfils an identified need to study the multi-objective optimisation techniques for integration of distributed generation in the concerned power system network. The paper proposes a novel plant-propagation-algorithm-based technique in appropriate allocation and sizing of distributed generation unit.
Prestige and Dominance: How eWOM Differs Between Consumers High in Authentic and Hubristic Pride

Electronic word-of-mouth (eWOM) influences consumers' purchase decisions, but few studies have investigated the antecedents that lead consumers to create different types of eWOM. From the perspective of social interactions, this research explored how two subtypes of pride not only compel consumers to create eWOM but also differently impact four types of eWOM and their mechanisms. Study 1 manipulated the pride state and found that authentic pride promoted positive eWOM and constructive eWOM, while hubristic pride promoted negative eWOM and destructive eWOM. Study 2 examined the effect of pride on eWOM at the trait level and tested the mediating effect of their use of social status pursuit strategy. Overall, this study increases the understanding of different types of eWOM and broadens the literature of the effect of pride and social status pursuit strategy in the context of consumption.
Abstract LB538: Characterization of GB263T, a tri-specific antibody against EGFR/cMET/cMET for NSCLC

Background: The EGFR tyrosine kinase inhibitors (TKIs) have been effectively used for non-small cell lung cancer (NSCLC) driven by EGFR mutations. However, patients eventually develop drug resistance via various mechanisms such as secondary EGFR mutations and activation of alternative pathways. The cMET amplification is one of the resistant mechanisms. Amivantamab, a bispecific antibody to EGFR/c-Met has shown that concurrent inhibition of EGFR and c-Met can overcome resistance of EGFR-TKIs and improve patient outcomes. Thus, amivantamab has been approved for the treatment of advanced NSCLC patients with EGFR exon20ins mutations in the US. GB263T is a novel EGFR/cMET/cMET tri-specific antibody with enhanced ADCC function. The current study has demonstrated GB263T exhibited robust anti-tumor activity by in vitro and in vivo studies. Methods: GB263T has been extensively characterized. The binding/blocking activities were analyzed by SPR and ELISA. The protein levels and phosphorylation of EGFR/cMET were detected by Western Blot. Internalization ability was evaluated by confocal microscope. ADCC function was tested by Jurkat-CD16A-NFAT-Luc reporter system. Various CDX and PDX models were used to evaluate the in vivo efficacy in tumor inhibition. Results: GB263T showed high affinity binding to EGFR and cMET, with robust blocking activity. Moreover, GB263T induced receptor internalization and EGFR/cMET phosphorylation in NSCLC cell lines. GB263T dose-dependently inhibited the proliferation of cells containing EGFR exon 20 insertion mutations and C797S mutations. In addition, potent ADCC function against NSCLC cell lines was observed. Significant in vivo anti-tumor efficacy was demonstrated by multiple tumor models of EGFR exon 20 insertion, EGFR C797S mutation, cMET amplification, and cMET exon 14 skipping mutation. Conclusions: GB263T is a novel tri-specific antibody that exhibited robust anti-tumor activity. The preclinical data indicate that GB263T has great potential to become an effective therapeutics in the treatment of NSCLC. Citation Format: Qinglin Du, Wengang Zeng, Xueyan Yang, Liwen Liang, Xueqin Li, Yan Li, Yiqi Cao, Zongjun Xia, Jing Zhang, Qian Ding, Shuhua Han. Characterization of GB263T, a tri-specific antibody against EGFR/cMET/cMET for NSCLC [abstract]. In: Proceedings of the American Association for Cancer Research Annual Meeting 2022; 2022 Apr 8-13. Philadelphia (PA): AACR; Cancer Res 2022;82(12_Suppl):Abstract nr LB538.
LQNM Solver Performance Manager Power Estimation Power Consolidation Manager Cost Manager Cost Mapping ARMA Filter Optimal Adaptation

Server consolidation based on virtualization is a key ingredient for improving power efficiency and resource utilization in cloud computing infrastructures. However, to provide satisfactory performance in such scenarios under changing application workloads, dynamic management of the consolidated resource pool is critical. Unfortunately, this type of management is also challenging in cloud platforms because of the inherent tradeoffs between power and performance, and between the cost of an adaptation and its benefit. In this paper, we present Mistral, a holistic controller framework that optimizes power consumption, performance benefit, and the transient costs incurred by various adaptations and the controller itself to maximize overall utility. Mistral can handle multiple distributed applications and largescale infrastructures through a multi-level adaptation hierarchy and scalable optimization algorithm. Through extensive experiments, we show that our approach outstrips other strategies, each of which represents addressing the tradeoff between only two objectives among power consumption, performance, and transient costs.
Short-term amendment of biosolid on agricultural soil: effects on C and N mineralization and microbial activity

Adding biosolids to agricultural soils can improve its quality through increased storage of C and N. A study to analyze the short-term impact of the addition of biosolids on the release of nutrients and the microbial activity in agricultural soil was carried out. The microbial biomass C (MB-C), urease activity (UA), and mineralization of N and C at different application rates of biosolids were evaluated (0 mg, 100mg and 200 mg of N-NH4+ kg-1). In addition, a biosolid-only treatment was tested. It was observed an increase in C and N mineralization, NH3 volatilization, and MB-C content, according to the application rate of biosolids. In biosolid treatments, UA increased 100% on average in the first seven days of incubation. These results suggest that the nutrient content in the soil is improved and microbial activity is positively stimulated.
Neuroprotection by Ozanimod Following Intracerebral Hemorrhage in Mice

The destruction of the blood-brain barrier (BBB) after intracerebral hemorrhage (ICH) is associated with poor prognosis. Modulation of sphingosine 1-phosphate receptor (S1PR) may improve outcomes from ICH. Ozanimod (RPC-1063) is a newly developed S1PR regulator which can selectively modulate type 1/5 sphingosine receptors. Here, we studied the impact of Ozanimod on neuroprotection in an experimental mouse model of ICH, induced by injecting collagenase type VII into the basal ganglia. Ozanimod was administered by gavage 2 h after surgery and once a day thereafter until sacrifice. The results demonstrate that Ozanimod treatment improved neurobehavioral deficits in mice and decreased weight loss after ICH. Ozanimod significantly reduced the density of activated microglia and infiltrated neutrophils in the perihematoma region. Furthermore, Ozanimod reduced hematoma volume and water content of the ICH brain. The results of TUNEL staining indicate that Ozanimod mitigated brain cell death. The quantitative data of Evans blue (EB) staining showed that Ozanimod reduced EB dye leakage. Overall, Ozanimod reduces the destruction of the BBB and exert neuroprotective roles following ICH in mice.
Robust Finite-Time Stability for Uncertain Discrete-Time Stochastic Nonlinear Systems with Time-Varying Delay

The main concern of this paper is finite-time stability (FTS) for uncertain discrete-time stochastic nonlinear systems (DSNSs) with time-varying delay (TVD) and multiplicative noise. First, a Lyapunov–Krasovskii function (LKF) is constructed, using the forward difference, and less conservative stability criteria are obtained. By solving a series of linear matrix inequalities (LMIs), some sufficient conditions for FTS of the stochastic system are found. Moreover, FTS is presented for a stochastic nominal system. Lastly, the validity and improvement of the proposed methods are shown with two simulation examples.
Intraarticular hip preservation procedures in healed Perthes disease: a systemic review and meta-analysis

Background: Data about surgical options in treatment of healed Perthes disease are limited. The authors conducted this systematic review and meta-analysis to compare two newly described surgical techniques: femoral head reduction osteotomy (FHRO) and relative femoral neck lengthening (RFNL) in the management of healed Perthes disease in terms of efficacy and complications. Methods: This systematic review and meta-analysis examined controlled and noncontrolled studies that compared FHRO and RFNL. The authors searched the Medline database via PubMed, EMBASE, and Cochrane Library for studies published between January 2000 and February 2021. Results: Fourteen studies that assessed RFLN and five studies that assessed FHRO were examined. The FHRO group demonstrated better improvement in the Harris Hip Score (HHS) than RFLN. The RFNL group showed better improvement than the FHRO group regarding flexion and internal rotation degree. The incidence of postoperative pain and postoperative stiffness was higher in the FHRO group than in the RFNL group. In the FHRO group, 28 patients with postoperative complications were reported (59.5%) versus 72 patients in the RFNL (16.4%). Conclusions: FHRO and RNFL are effective and safe modalities for post-Perthes sequelae. However, the postoperative clinical outcomes were observed to be in favor of RFNL, with less incidence of postoperative complications compared to the FHRO. Moreover, the FHRO group needed more secondary acetabular procedures than the RFNL group. On the other hand, FHRO showed greater improvements in radiographic coverage indices. Level of Evidence: Level III.
Time from Injury to Initial Operation May Be the Sole Risk Factor for Postoperative Leakage in AAST-OIS 2 and 3 Traumatic Duodenal Injury: A Retrospective Cohort Study

Background and Objectives: Traumatic duodenal injury is a rare disease with limited evidence. We aimed to evaluate the risk factors for postoperative leakage and outcomes of pyloric exclusion after duodenal grade 2 and 3 injury. Materials and Methods: We reviewed a prospectively collected trauma database for the period January 2004–December 2020. Patients with grade 2 and 3 traumatic duodenal injury were included. To identify the risk factors for postoperative leakage, we used a stepwise multivariable logistic regression model and a least absolute shrinkage and selection operator (LASSO) logistic model. We constructed a receiver operator characteristic (ROC) curve to predict risk factors for postoperative leakage. Results: During the 17-year period, 179,887 trauma patients were admitted to a regional trauma center in Korea. Of these patients, 74 (0.04%) had duodenal injuries. A total of 49 consecutive patients had grade 2 and 3 traumatic duodenal injuries and underwent laparotomy. The incidence of postoperative leakage was 32.6% (16/49). Overall mortality was 18.4% (9/49). A stepwise multivariable logistic regression and LASSO logistic regression model showed that time from injury to initial operation was the sole statistically significant risk factor. The ROC curve at the optimal threshold of 15.77 h showed the following: area under ROC curve, 0.782; sensitivity, 68.8%; specificity, 87.9%; positive predictive value, 73.3%; and negative predictive value, 85.3%. There was no significant difference in outcomes between primary repair alone and pyloric exclusion. Conclusions: Time from injury to initial operation may be the sole significant risk factor for postoperative duodenal leakage. Pyloric exclusion may not be able to prevent postoperative leakage.
Landsat 9 Thermal Infrared Sensor 2 On-Orbit Calibration and Initial Performance

The Thermal Infrared Sensor 2 (TIRS-2) on Landsat 9 (L9) was launched on September 27, 2021, and underwent a variety of tests during its commissioning phase to establish its postlaunch performance. We report on the calibration updates performed to maintain its calibration and generate high-quality imagery. This is done by transferring the SI-traceable prelaunch calibration to on-orbit while accounting for changes in the TIRS-2 response as detected through on-board calibrator observations. Additional empirical corrections were implemented to mitigate image striping observed on-orbit. The detector arrays were monitored through its commissioning phase to ensure that stable detectors were chosen for operations. TIRS-2 has demonstrated ~0.025% instability over its orbit, ~80-mK noise equivalent delta temperature (NEdT), and an absolute radiometric uncertainty <1.4% in its nominal temperature range enabling a wide array of Earth science applications.
Lighting-on-Demand: Balancing Occupant Needs and Energy Savings

ABSTRACT Lighting on demand (LOD) is a high-resolution energy-efficient lighting control technique that dynamically adjusts the lights in a space according to its occupancy. It controls the lights in the space individually such that the area that receives a higher light level is determined by the location of the occupant(s) and, in some cases, by their tasks. In our LOD system, the controls adjust the individual lights above and around the occupant to track him or her while traversing a circulation space. We developed three scenarios with different combinations of light levels in the occupancy and background areas. We built a test bed, developed an occupancy algorithm, and conducted a usability test to demonstrate the acceptability of the LOD system to people walking in the circulation space by asking them to evaluate the conditions they experienced and measuring their walking time. Our test results suggest that in the case of individual occupants walking in a circulation space, the LOD concept is generally acceptable, but there are limits to the dimming potential both for the occupancy area and the background area. Satisfaction seems to be more strongly related to the occupancy area, but walking speed depends on the background level toward which one walks.
National Guidelines for Trauma-Aware Education in Australia

The National Guidelines for Trauma-Aware Education in Australia were developed in response to a rapidly growing interest in trauma-aware education across the country and to address the lack of site- and system-level guidance for application of trauma-aware practices in schools and early childhood services. Although research into trauma-aware education was increasing and resources and training and support programs were being developed across Australia, there were no nationally agreed upon guidelines providing consistency to thinking, policy, and practice. Drawing from public health and health promotion models for establishing guidelines for trauma-aware policy and practice, the Guidelines were developed through a thorough process of incorporating research evidence and expert and end-user input. The Guidelines were developed across 2017–2019 and were finalized in 2021 and provide an important first step in a national response to trauma-aware education in Australia. This article will describe the “story” behind the development of the Guidelines. It is hoped that this “story” will help others considering development of systemic resources to inform the establishment and enhancement of trauma-aware policy and practice in schools and early childhood education services.