Miracle-dz/UniFAR-FTUs huggingface dataset:
The association of the Arg1277Gln mutation in the MYH7 gene with myosin storage myopathy in a Chinese family

Background Myosin storage myopathy (MSM) is caused by missense mutations in the MYH7 gene, which encodes the β-cardiac/slow skeletal muscle myosin heavy chain rod (MyHCI). MSM is an autosomal dominant/recessive myopathy characterized by subsarcolemmal accumulations of myosin in type I muscle fibers that results in weakness of the scapula, limb and distal muscles.Methods Here, we report a MSM phenotype that was present across three generations of individuals from the same family, one of whom was a neonate.Results At birth, the neonate had an elevated creatine kinase level and decreased muscle tone in the limbs. At 2 months of age, the infant’s cervical vertebrae caused his head to be skewed to the right. At 7 months of age, the infant’s development was delayed.Whole exome sequencing showed a novel heterozygous variant NM_000257. 3: c.3830G>A (p.Arg1277Gln) at exon 28 of the MYH7 gene in the DNA of the infant and his father.Conclusions Previously, which site has only been reported in 2 cases of cardiomyopathy; therefore, this study expands our knowledge of the clinical phenotypes associated with mutations within the rod region of MyHCI. Importantly, close follow-up of the neonate will provide important information on the natural history of MSM associated with MYH7 gene mutation.
The Asocial Responselessness of Unfocused Interaction in Computer Mediated Communication

This thesis contributes to the domain of awareness information. Awareness information can be viewed as a fundamental building-block of social media, visualizing people and their activities in an online setting. With life becoming more and more influenced by social media such as Facebook, Flickr, Twitter, Linkedin and Digg, it becomes important for designers of social media to have an understanding of how users respond to awareness information. An online gallery of pictures was developed and equipped with a chat and a basic awareness information system. Usage data was collected by the system and analyzed combining qualitative as well as quantitative approaches aiming to explore the influence awareness information have on the usage of the system. The analysis reveals that awareness information is a powerful tool triggering social behaviour. It is, at the same time, challenging to implement in a way that it provides a sound environment for social interaction. This was manifested by co-present users both stayed longer in the system and also was inclined to take a different path through the gallery than the solitary user. However, the interaction that took place in the gallery was characterized by frequent conversational break-downs and irritation among users. Results indicate that this is, in part, due to the lack of built-in social norms guiding users in their activities in the system. Subsequently, it is important to facilitate the creation, recreation and reinforcement of social norms when designing social systems.
Games That Teach Teams: 21 Activities to Super-Charge Your Group!

Preface. Acknowledgements. SETTING THE STAGE. What Is a Team? Building a Team. Facilitation. Team Games. TWENTY-ONE TEAM GAMES-BOOK AT A GLANCE-BELL HOP-BOX OF CHOCOLATES-BRAIN FRAME-BUZZ WORD-CROSS ROADS-DUEL IDENTITY-HIGH FIVE-LINE UP-MATCH POINT-NAME THAT TEAM-NORMAN SAYS! -PASS THE BUCK-POWER TAG-RAT RACE-REGARDS-SENTENCE PROMPT-SNOW BALL-SUPER MODEL-TEAM ROAST-TOOTH AND NAIL-WW.WHERE AND WW.WHEN. About the Authors.
Using software-defined networking principles for wireless sensor networks

In this paper, we propose an architecture based on software-defined networking (SDN) for wireless sensor networks. Ideas of how to design and make use of the flexibility that SDN offers are presented. We discuss how SDN principles can lead to the use of commodity hardware in a wider range of WSN deployments and then tailor the software only to meet the requirements of the specific deployments and their applications. A few examples are introduced that demonstrate how the architecture can be used for networking, in-network processing, and performance predictions.
Sport and fitness app uses: a review of humanities and social science perspectives

Abstract Sport and fitness mobile applications (SFMAs) have led to significant changes in how people engage in sport and physical activity. This development is part of a broader trend of self-tracking (the ‘quantified self’) and gamification, whose effects are discussed in an increasing number of publications in the humanities and social sciences. The aim of this interdisciplinary literature review is to provide an overview of the main research results on these apps. It summarises their emergence and the discourse of those who promote them, the factors leading to their adoption, their uses in practice, the reasons for their abandonment or rejection, and the risks and perverse effects linked to their use. The main sociological, psychological and philosophical interpretations of the phenomenon are also outlined: mobile applications as a tool for behaviour change, the agentive capacities of these sociotechnical systems, and the contemporary imperative of self-management. Some users find real support in SFMAs to set goals, plan their sessions, and/or to make physical activity a regular routine. However, for others, their use becomes excessive, leading to frustration or changes in social behaviour. Many studies point out the difficulty of engaging athletes in the use of SFMAs in a lasting way. While instances of long-term and balanced use are not uncommon, they coexist with use that borders on obsession, or even forms of dependence. We conclude with current research priorities and highlight avenues of research that merit further study.
Using Context-based Statistical Models to Promote the Quality of Voice Conversion Systems

This article aims to examine methods of optimizing GMM-based voice conversion systems performance in which GMM method is introduced as the basic method for improvement of voice conversion systems performance. In the current methods, due to using a single conversion function to convert all speech units and subsequent spectral smoothing arising from statistical averaging, we will observe quality reduction. In this paper, after introducing GMM2 method, several GMM models will be used to model each phoneme. Furthermore, in the stage of corresponding the clusters of each state, before applying Dynamic Time Warping algorithm, we use a LMR conversion for further correspondence among the parameters of two corresponding states of two speakers. Another reason for quality reduction in voice conversion system is that the precision of speech signal parameters was underestimated. In order to overcome such a problem, Generalized Harmonic Model is introduced which is replaced by sinusoid harmonic model applied in GMM2 giving another method called GMM3. Finally, we will present GMM4 method, the objective of which is to promote the system performance with limited data and a restricted number of demi-syllables to train conversion functions.
Several Ways Generation Z May Shape the Medical School Landscape

Just as medical colleges have adapted to the Millennial generation of students, a new generation is poised to enter as matriculants. Learner attributes of this generation, Generation Z, are in stark contrast to previous ones, but more than that, they provide new challenges that undergraduate universities are already facing. This article aims to highlight some of these challenges, including those relating to student counseling services, volunteering activities, learning environments, and learner perspectives. These challenges are framed and discussed within the context of medical education.
Nanosensors : theory and applications in industry, healthcare and defense

Carbon-Nanotube-Based Sensors, Lianxi Zheng and B.C. Satishkumar Carbon-Nanotube-Based Fluidic Shear-Stress Sensors, Winnie W.Y. Chow, Yanli Qu, and Wen J. Li Nanomechanical Cantilever Sensors: Theory and Applications, Yifan Liu, Wen xing Wang, and Wen miao Shu Protein Thin Films: Sensing Elements for Sensors, Laura Pastorino and Svetlana Erokhina FRET-Based Nanosensors for Intracellular Glucose Monitoring, Jithesh V. Veetil, Sha Jin, and Kaiming Ye Noble Metal Nanoparticles as Colorimetric Probes for Biological Analysis, Xiaodi Su Optical Capillary Sensors for Intelligent Classification of Microfluidic Samples, Michal Borecki and Michael L. Korwin-Pawlowski Future Healthcare: Bioinformatics, Nano-Sensors, and Emerging Innovations, Shoumen Palit and Austin Datta Index
Identifying potential health and safety risks at the pre-construction stage

Previous researches have demonstrated that decisions made during the pre-construction stage have a big influence on the construction worker safety. This paper introduces a systematic approach for dealing with health and safety risks during the pre-construction stage. The developed methodology helps designers to calculate the safety-related performance of their residential construction designs, providing a consistent basis for comparisons between them. In order to avoid a typical shortcoming in the evaluation of health and safety risks, indicators are based on quantitative data available in the
European Defence Equipment Collaboration: Britain’s Involvement, 1957–87

Stages for collaboration the NATO background - 1957-1976 Ministry of Defence organization and collaboration - 1957-1976 the NATO background - 1976 to 1987 Ministry of Defence organization and collaboration - 1976 to 1987 the defence industry and collaboration - 1957 -1987 the Royal Navy and collaboration case studies in collaboration - the Royal Ordnance factories and the MBT, - the helicopter as a collaborative project problems, partners and people British policy towards equipment collaboration - a summary and a forward look.
Design of slit loaded Planar and Curved Patch Antenna

Slit loaded circularly polarized patch antenna embedded on planar structure and curvature structure were investigated. The curvature effect on slit loaded patch antenna determines the limiting value of radius of curvature to obtain circular polarization. At a certain radius of curvature (ROC) around 131.3 mm, circular polarization have been obtained with axial ratio band width around 15 MHz and return loss bandwidth around 56 MHz compared with 17 MHz and 65 MHz as that of planar structure. The beam width responsible for coverage of planar patch are 104 and 107 degree with respect to 84 degree and 124 degree of curved patch at phi = 0 and 90 degree respectively.
Victim Localization Using RF-signals and Multiple Agents in Search a Rescue

A common problem in existing Search And Rescue (SAR) systems is that they must be activated by the missing person in order to work. This requires an awareness of the the risk of becoming distressed, which in many cases is not feasible. Furthermore, most of the localization systems require specialized hardware.In this thesis, the victim is assumed to wear a cellphone that could be located using readily available consumer electronics. A method of estimating the position of a transmitter, given radio signal measurements at different locations, is developed and verified with real and simulated data. A proof-of-concept system is built in which several users can jointly collect received signal strength data at different locations using mobile phones. The system analyzes the data in real-time and guides the users in the search by estimating the origin of the signal.An outdoor field test is conducted in which the searchers using the system are able to locate the hidden target phone without prior knowledge regarding the position. We are able to localize the victim with an accuracy of 10-20 meters in a timely manner using android smartphones. This shows the potential of a similar system in \abbrSAR scenarios. However, more work is needed to make the system viable in real scenarios and to remove some of the delimitations of the current implementation.
Traffic Incident Management: A Common Operational Picture to Support Situational Awareness of Sustainable Mobility

Successful traffic incident management presupposes a multi-disciplinary approach. To meet appropriately the safety and mobility needs of all affected parties, traffic incidents call for a high level of collaboration and coordination of involved agencies. Effective traffic incident management activities rely in particular on flexible communications and information systems.Based on experiences from the military domain it is possible to develop strategic concepts that are related to the improvement of information sharing and collaboration. Such concepts can also be applied to enhanced traffic incident management information systems. The present paper aims to offer a review of the state of the art in this field and to illustrate the empirical usefulness and benefits of traffic incident management.
Map-based Mobile Services: Theories, Methods and Implementations

The development of wireless telecommunication and ubiquitous computing te- nologies has led to a growing mobile population and dramatically changed p- terns of working and everyday life. A smooth and safe mobility is only possible when the mobile person is well-informed of the happenings in his ambient en- ronments. Location-sensitive maps have proved a strong enhancement to what a mobile user can directly perceive from his ambient environments. Since ancient times the map has been the favorite communication language of spatial infor- tion. It is even more the case for mobile applications where brand-new maps can be wirelessly retrieved or generated in real-time. The upsurge of map-based s- vices on mobile devices has raised a number of new questions challenging the conventional computer-assisted cartography. Map-based mobile services provides a contemporary overview of research and development issues related to the design and the use of mobility-supporting maps. The book has been written for professional cartographers who are striving for - tending their theoretical, methodological and practical knowledge to mobile m- making, for surveyors and geo-service providers involved in the development of intelligent location-based services, for software developers and cognitive scientists engaged in human-computer interaction, and for students and academics in cart- raphy and geoinformation sciences. The book was initiated by the multidisciplinary workshop Design of m- based mobile services within the frame of the conference Human and Computer 2003 Interaction on the movement held in Stuttgart, Germany, September 2003.
Gsm Based Vehicle Inspection and Verification System

GSM Based Vehicle Registration system is a system that helps in the verification and inspection of road worthy cars and it is also used to track stolen vehicles by accessing the motor licensing database wirelessly. The system is made up of a user's mobile phone, a GSM modem interfaced to a PC through as serial port, the PC is functioning as a server, and a software developed in VB.NET. A Table Adapter is included, a relational database used was created using an MS-Access and database access codes were written in Structural Query Language. Users send Query to the GSM Modem attached to the PC, with the help of an application software that was developed. The modem helps the PC to access the query through AT Commands. An SQL Query is used to access the database for a fitting response. The project is suitable for a broad range of applications on wireless database access as it can be applied in various areas of human life. The software can be customized to fit in any organization. A University student can use it to check for his/her result wirelessly. It could be used to track fake drugs by the drug administrators. It could be used in the library to make enquiry of any type of book. Generally, it is used to access data wirelessly anywhere, anytime, even locations outside the country that has a GSM coverage.
Video Processing and Communications

From the Publisher: Yao Wang received the B.S. and M.S. degrees in electrical engineering from Tsinghua University, Beijing, China, in 1983 and 1985, respectively, and the Ph.D. degree in electrical and computer engineering from the University of California at Santa Barbara in 1990. Since 1990, she has been with the Faculty of Electrical Engineering, Polytechnic University, Brooklyn, NY. Her research areas include video communications, multimedia signal processing, and medical imaging. She has authored and co-authored over 100 papers in journals and conference proceedings. She is a senior member of IEEE and has served as an Associate Editor for the IEEE Transactions on Circuits and Systems for Video Technology and the IEEE Transactions on Multimedia. She won the Mayor's Award of the City of New York for Excellence in Science and Technology in the Young Investigator category in 2000. Jvrn Ostermann studied electrical engineering and communications engineering at the University of Hannover and Imperial College London, respectively. He received Dipl. -Ing. and Dr.-Ing. from the University of Hannover in 1988 and 1994, respectively. He has been a staff member with Image Processing and Technology Research, AT&T Labs>Research since 1996, where he is engaged in research on video coding, shape coding, multi-modal human-computer interfaces with talking avatars, standardization, and image analysis. He is a German National Foundation scholar. In 1998, he received the AT&T Standards Recognition Award and the ISO award. He is a member of the IEEE, the IEEE Technical Committee on Multimedia Signal Processing, and chair of the IEEE CAS Visual Signal Processing and Communications (VSPC) TechnicalCommittee. Ya-Qin Zhang received the B.S. and M.S. degrees in electrical engineering from the University of Science and Technology of China (USTC) in 1983 and 1985, respectively, and the Ph.D. degree from George Washington University in 1989. He is currently the Managing Director of Microsoft Research in Beijing, after leaving his post as the Director of Multimedia Technology Laboratory at the Sarnoff Corporation in Princeton, NJ (formerly the David Sarnoff Research Center, and RCA Laboratories). He has been engaged in research and commercialization of MPEG2/DTV, MPEG4/VLBR, and multimedia information technologies. He has authored and co-authored over 200-refereed papers in leading international conference proceedings and journals. He has been granted over 40 U.S. patents in digital video, Internet, multimedia, wireless and satellite communications. He was the Editor-in-Chief of the IEEE Transactions on Circuits and Systems for Video Technology from 1997 to 1999. He is a Fellow of the IEEE.
RNA Polymrase II gene expression in clinical Leishmania major isolates with no-response-to-drug pattern

Cutaneous leishmaniasis (CL) is one of the most important infectious diseases in the world and is increasing day by day. No effective vaccine has been made against this disease, so far. An important issue with this disease is the development of drug resistance or no response to drug, which is going to spreading that its mechanism has not yet been completely identified. The main aim of this study was to assessment the expression of RNAPII gene in no response to drug and susceptible isolates of Leishmania major. The patients with CL from the central and North of Iran were considered for this study. The samples were transferred in RNAlater solution and stored in -20 °C. RNA extraction and cDNA synthesis were performed. The gene expression analysis was done with SYBR Green Real Time PCR. Written informed consent was filled up by patients and then information forms were written based on Helsinki declaration. Statistical analysis was done with SPSS (16.0; SPSS Inc, Chicago) using independent t-test. P ≤ 0.05 was considered significant. It was observed that the gene expression of RNAPII in the no response to drug isolates was lower than that the one in drug sensitive isolates. A change in the expression of RNAP II in no response to drug isolates of L. major can indicate the potential role of this gene in the related mechanism.
On the Design of Acousto-Ultrasonics - Pattern Recognition Classifiers for the Identification of Material Response States

This paper deals with the design procedure of computer-based Pattern Recognition (PR) Classifiers, when the Acousto-Ultrasonics (AU) technique is employed for the identification of material response states. For this purpose, material specimens presenting different mechanical response states are processed to retrieve AU signals in the form of digitalized records. The retrieved AU data are, then, grouped in distinct classes, each pertaining to a known response state of the material under consideration. These AU data are, subsequently, identified by pattern vectors, the components of which represent values of characteristic features in certain domains of description. PR-classifiers built from these pattern vectors are subsequently used to identify unknown response states of the material by classifying their pertaining AU signals as belonging to one of the predefined classes. In the paper, AU-experimental work in conjunction with PR-computational results are presented to illustrate the design procedure and testing of PR-classifiers for the purpose of identifying various low-energy repeated-impact states of a class of polymeric material; namely, Polyvinylchloride (PVC).
Implications of implementing the European asphalt test methods

With the implementation of the asphalt package of European standards and the withdrawal of the equivalent British Standards in January 2008, the basis of the tests called in the Specification for Highway Works will have to change. This harmonisation of test methods for bitumen and asphalt will mean that the numerical values in requirements may need to be adjusted in order to maintain the same level of performance as prior to the change. Therefore, each test called up in the Specification for Highway Works has been reviewed alongside the harmonised European Standard that will replace it and the pair of standards have been categorised as being Identical, Related or Distinct. Comparative trials were undertaken on the tests for the determination of the texture depth of pavement surfaces, the storage stability of modified binders and the wheel-tracking properties of asphalt mixtures in order to determine what revision is needed to the numerical values of the limits imposed on those properties. (A)
A Virtual Data Warehouse for Manufacturing Industry

Data warehousing is the best solution to relieve the database management systems to hold the long standing data which will go on mounting from day to day business transactions. But creating and managing a data warehouse are complex tasks and in addition, data warehouse tools available in the market are very expensive. To make the data warehouse solutions cost-effective, creation of virtual data warehouse is one option in the case of applications having limited scope or limited duration. This paper deals with the development of such virtual data warehouse for effective supply chain management for a multi-national software development and consultancy company dealing with big semiconductor manufacturing industries. The design and development of the virtual data warehouse is described in detail using the existing database management systems and the existing huge database of the companies. The data warehouse has been created based on the important business requirements, identifying the relevant existing data sources that can be integrated together to generate respective dimensional tables and thereby the fact tables and then finally completing the multi-dimensional models to derive answers to the respective queries. The paper also presents some screen shots of the application interface.