Miracle-dz/UniFAR-FTUs huggingface dataset:
Avaliação metrológica de um robô industrial para montagem estrutural de aeronaves

The aircraft fuselage assembly process is too labor intensive and highly manual within the Brazilian aircraft industry. Foreign companies of this industrial segment started the adoption of automated solutions in the last two decades. Their automated solutions are very product dependent as well as very expensive. This kind of solution is inadequate for the Brazilian aircraft industry. This paper shows the preliminary results of a flexible, low cost automated system specially designed to fit the Brazilian requirements. This is based upon the usage of industrial robots for general purposes. In order to check the feasibility of such a solution, the process requirements are expressed in terms of accuracy, repeatability and resolution of the robots. These characteristics are measured by two independent, state-of-art measurement systems, namely, Indoor GPS and photogrammetry device. The initial results allow one to conclude that the robot can be used for the purpose described herein as long as it is assisted by correction process based upon the very measurement systems used to acquire its operational characteristics
Study of effect of wood-flour content on mechanical, thermal, rheological properties and thermoformability of wood-polypropylene composites

Abstract Wood plastic composites (WPC) were made from polypropylene (PP), impact copolymer (ICP) and wood flour (WF) by varying the WF content from 10 to 40% with PP grafted maleic anhydride as a coupling agent. The effect of varying WF content was studied on rheological, thermal, mechanical properties and dynamic mechanical properties. Experimental small amplitude oscillatory shear (SAOS) data was compared with the Einstein–Batchelor and empirical Krieger–Dougherty relations. Significant dependence of mechanical and rheological properties on WF content was observed. Young’s modulus, flexural modulus and dynamic shear viscosity increased with WF content. Results of dynamic mechanical analysis (DMA) showed increase in storage modulus with WF content. Three millimeter thick compression molded composites sheets were thermoformed using axisymmetric molds with two draw depths. Sag observed visually during thermoforming decreased with increasing WF content. Components made from the composites showed close to uniform thickness distribution as compared to those from ICP.
Prevalence, Intensity of Soil-Transmitted Helminths, and Factors Associated with Infection: Importance in Control Program with Ivermectin and Albendazole in Eastern Côte d'Ivoire

Evaluation of soil-transmitted helminths (STHs) and implementation of additional interventions are required in the region of a filariasis control program, given that antifilariasis drugs also have a beneficial effect on STHs. Thus, this study determines the extensive epidemiology of STHs to improve their successful control. Stool samples were analyzed using the Kato-Katz method. Chi-squared and Kruskal-Wallis tests were used to measure differences in infection rates and intensities, respectively, and logistic regression identified the risks of infection. The main intestinal helminths (A. lumbricoides, hookworm [N. americanus], S. mansoni, and T. trichiura) were found in the population. The overall prevalence of STHs was 19.5%. The prevalence of hookworm, the predominant species, ranged from 2% (n=6) to 28% (n=97). The overall prevalence of the other intestinal helminths was less than 6% (n=18). Intensity of hookworm was mostly light with a range from 1.6% (n=5) to 25.9% (n=90). However, the intensity of the species was significantly greater in Soribadougou compared to the other localities. Heavy infection was found in old children and adults but not in young children. Open defecation (OR=3.23, p≤0.05), dog/cat raising (OR=1.94, p≤0.05), farming (OR=14.10, p≤0.05), and irrigated culture (OR=3.23, p≤0.05) were positively associated with hookworm. It was observed that the participants missed the follow-up examinations due to trip (32.7%) or misunderstanding (15%) and lack of information (11.8%) of the purpose of the survey. Thus, to sustain the control of STHs, the MDA program should target the entire community and add education about the use of toilets, best practices of farming, and dog/cat raising.
A Study of Virtual Remote Laboratory and its Subsystem by Using Modelica

iEELab((Internet-based Electrical Engineering Lab) at Zhejiang University is an integrated laboratory including physical and virtual remote experiments. This paper first makes a brief introduction to the overall architecture of iEELab. Then, focusing on the virtual remote laboratory which uses a unified object-oriented language Modelica for modeling and simulation, we elaborate its architecture and the internal mechanism of virtual remote lab operation. Finally, taking a subsystem of iEELab-the plate angle control experiment system as an instance of the virtual remote lab, we display the process of modeling and simulation of virtual experiments using modelica.
Anthocyanin content and storage stability of spray/freeze drying microencapsulated anthocyanins from berries: a review

Abstract A comprehensive literature search for articles published on spray and freeze-dried anthocyanins from a large variety of berries was performed. Out of a total of two-hundred and eight collected values, anthocyanin content in encapsulates had a 120-fold variation depending on the raw material and type of encapsulating agents. Highest observed anthocyanin concentration amounted to about 3500 mg/100 g powder. In most cases increasing the amount of encapsulant agents led to a noticeable reduction in the concentration of anthocyanins, this being attributable to a predominance of the dilution effect. Retention of encapsulated anthocyanins after storage at 25 °C (in darkness) for periods between 90 and 180 days were in the range of 80–67%, as long as the water activity (aw) was 0.33 or less. Some predicted values of half-time (t1/2) from literature must be taken with precaution since in many cases they were derived from experimental measurements taken at storage times smaller than predicted half times. Anthocyanin degradation during storage occurred even below the glass transition temperature (Tg) of the amorphous matrices.
Location service for wireless network using improved RSS-based cellular localisation

Value-added services, especially in mobile environments, have recently become the key component of making more profit and attracting more subscribers. One of the most commonly used such service is location-based advertiser services. The main issue which should be considered in providing such services is determining the position of the mobile terminals precisely. In this paper, one pattern recognition localisation method based on the signal strength appropriated for implementing a location-based service is presented. The main aim is to introduce some practical solutions to decrease error and computational load and also eliminate the necessity of updating the database. Practical results illustrate high accuracy of this technique and its suitability to apply in such services. The mean error declines to 9.7 m and mean error corresponding to CDF = 67% and CDF = 95% are less than 11 m and 23 m, respectively. We also present a location-based advertising service, in which the customer’s interests and local time are considered, in order to enhance the efficiency and individualism of this service.
Isobutanol tolerance and production of Saccharomyces cerevisiae can be improved by engineering its TATA‐binding protein Spt15

Low isobutanol tolerance of Saccharomyces cerevisiae limits its application in isobutanol fermentation. Here, we used global transcription machinery engineering to screen mutants with higher isobutanol tolerance and elevated isobutanol titres. TATA‐binding protein Spt15 was used as the target of global transcription machinery engineering for improvement of such complex phenotypes. A random mutagenesis library of S. cerevisiae TATA‐binding protein Spt15 was constructed and subjected to screening under isobutanol stress. A mutant strain (denoted as spt15‐3) with improved isobutanol tolerance was identified. There were three mutations of Spt15 in strain spt15‐3, including deletion of A at position −132 nt upstream of initiation codon, insertion of G at position −65 nt upstream of initiation codon and a synonymous mutation at position 315 nt (T → C) downstream of initiation codon. We then metabolically engineered isobutanol synthesis in strains harbouring plasmids YCplac22 containing these Spt15 mutations. Delta integration was used to overexpress ILV3 gene, and 2μ plasmids carrying PGK1p‐ILV2 and PGK1p‐ARO10 were used to overexpress ILV2 and ARO10 genes. After 24‐h micro‐aerobic fermentation, Engi‐3 produced 0·556 g l−1 isobutanol, which was 404% and 25·3% greater than isobutanol produced by control Engi‐1 and engineered Engi‐2, respectively. After 28 h, Engi‐4 produced 0·459 g l−1 isobutanol, which was 315% and 3·2% greater than isobutanol produced Engi‐1 and Engi‐2, respectively. RNA‐Seq‐based transcriptome analysis shows that mutations of Spt15 in strain spt15‐3 increased the expression of SPT15. Meanwhile, compared with strain Engi‐3, the spt15‐3 mutation downregulated the expression of genes involved in the TCA cycle and glyoxylic acid cycle, but increased the expression of genes related to cell stability. This work demonstrates that isobutanol tolerance and production of S. cerevisiae can be improved by engineering its TATA‐binding protein Spt15. This study clarified the molecular mechanisms regulating isobutanol production and tolerance in S. cerevisiae.
Can project monitoring and control be fully automated?

An extended research programme has examined over the past two decades how productivity in construction projects can be improved through the development of models for project monitoring and control, which process automatically collected data on the actual project performance. Tests that were conducted with these models demonstrate that this approach can help overcome some of the limitations of existing manual methods. However, they also indicate that certain manually obtained data are still required in addition to the automatically collected data. A framework for semi-automated project monitoring and control is proposed, in which both manually and automatically collected data can be incorporated. This framework integrates the monitoring of projects with their control by taking into account the impact on productivity of existing deviations from the planned performance, and of the controlling actions that are proposed to deal with these deviations.
Using Animation to Enhance 3D Visualization: A Strategy for a Production Environment

The use of animation can significantly enhance the visualization of three-dimensional (3D) structures. It can present a focused train of thought, or it can be used to systematically scan through previously unfathomable quantities of data to examine for unknown features and consistencies. In order to establish a modern animation facility requires a variety of technical, psychological and artistic skills, in addition to advanced computer graphics and related equipment. 3D graphics combined with animation has proven to be a very effective tool in storytelling. The dynamic visual image is uniquely suited for thought experiments, simulations and traversing vast quantities of data otherwise incomprehensible to the human mind. Sometimes animation is the only method that allows a clear presentation of complex empirical or theoretical information in many dimensions. Scientific visualization is by its nature an exploratory process. And frequently animations are iteratively refined and polished to enhance comprehensibility for the researchers and their peers.
Process independent automated sizing methodology for current steering DAC

This study introduces a process independent automated sizing methodology based on general regression neural network (GRNN) for current steering complementary metal-oxide semiconductor (CMOS) digital-to-analog converter (DAC) circuit. The aim is to utilise circuit structures designed with previous process technologies and to synthesise circuit structures for novel process technologies in contrast to other modelling researches that consider a particular process technology. The simulations were performed using ON SEMI 1.5 µm, ON SEMI 0.5 µm and TSMC 0.35 µm technology process parameters. Eventually, a high-dimensional database was developed consisting of transistor sizes of DAC designs and corresponded static specification errors obtained from simulation results. The key point is that the GRNN was trained with the data set including the simulation results of ON-SEMI 1.5 µm and 0.5 µm technology parameters and the test data were constituted with only the simulation results of TSMC 0.35 µm technology parameters that had not been applied to GRNN for training beforehand. The proposed methodology provides the channel lengths and widths of all transistors for a newer technology when the designer sets the numeric values of DAC static output specifications as Differential Non-linearity error, Integral Non-linearity error, monotonicity and gain error as the inputs of the network.
Cross-layer knowledge distillation with KL divergence and offline ensemble for compressing deep neural network

Deep neural networks (DNN) have solved many tasks, including image classification, object detection, and semantic segmentation. However, when there are huge parameters and high level of computation associated with a DNN model, it becomes difficult to deploy on mobile devices. To address this difficulty, we propose an efficient compression method that can be split into three parts. First, we propose a cross-layer matrix to extract more features from the teacher's model. Second, we adopt Kullback Leibler (KL) Divergence in an offline environment to make the student model find a wider robust minimum. Finally, we propose the offline ensemble pre-trained teachers to teach a student model. To address dimension mismatch between teacher and student models, we adopt a $1\times 1$ convolution and two-stage knowledge distillation to release this constraint. We conducted experiments with VGG and ResNet models, using the CIFAR-100 dataset. With VGG-11 as the teacher's model and VGG-6 as the student's model, experimental results showed that the Top-1 accuracy increased by 3.57% with a $2.08\times$ compression rate and 3.5x computation rate. With ResNet-32 as the teacher's model and ResNet-8 as the student's model, experimental results showed that Top-1 accuracy increased by 4.38% with a $6.11\times$ compression rate and $5.27\times$ computation rate. In addition, we conducted experiments using the ImageNet$64\times 64$ dataset. With MobileNet-16 as the teacher's model and MobileNet-9 as the student's model, experimental results showed that the Top-1 accuracy increased by 3.98% with a $1.59\times$ compression rate and $2.05\times$ computation rate.
Wavelength demultiplexing heterojunction phototransistor

Experimental and theoretical results on a wavelength demultiplexing receiver composed of an AlGaAs/GaAs heterojunction phototransistor (HPT) integrated within a resonant cavity are reported. A high quality factor cavity was formed using a very thin In0.05Ga0. 95As active absorption layer in the collector depletion region of the HPT. Crosstalk attenuations of 15dB for dual and 12dB for triple wavelength demultiplexing were demonstrated. The individual HPTs had an optical gain of 500 at the resonant modes. Theoretical calculations predict crosstalk attenuation levels as high as 40 dB with high reflection mirrors on both ends of the cavity.
Scintillation Counter for the Detection of α‐Particles

A simple battery‐operated survey instrument has been developed which uses a photo‐multiplier tube to detect the scintillations produced in a phosphor by α‐particles. The electrical components are a 1100‐volt battery pack; a 931A photo‐multiplier tube; a matching transformer and headphones for registering single particles; and a crystal rectifier, choke, and meter for use with strong sources. The latter group of components are used in a novel ``charge‐multiplying'' circuit which increases the meter sensitivity by a factor of 12. The instrument is insensitive to β‐ and γ‐radiations.
A new approach to dynamic analysis of AC networks incorporating detailed modeling of DC systems. I. Principles and implementation

A digital simulator that permits the integration of an AC transient stability program with a detailed simulation of a DC system is discussed. It provides a means of overcoming limitations of AC studies for which discontinuous and distorted interactions with DC networks are not accurately predicted. The response of the DC network takes into account the dynamics of a large system without the compromises of severe network reduction. A departure from previous practice extends the locations for interfacing the simulations away from the converter buses, and multiple interfaces are accommodated. The interfacing methods and scheduling are described. A simple test example is provided. >
Kinase Inhibition as Treatment for Acute and Chronic Graft-Versus-Host Disease

Allogeneic hematopoietic stem cell transplantation (allo-HCT) is a potentially curative therapy for patients suffering from hematological malignancies via the donor immune system driven graft-versus-leukemia effect. However, the therapy is mainly limited by severe acute and chronic graft-versus-host disease (GvHD), both being life-threatening complications after allo-HCT. GvHD develops when donor T cells do not only recognize remaining tumor cells as foreign, but also the recipient’s tissue, leading to a severe inflammatory disease. Typical GvHD target organs include the skin, liver and intestinal tract. Currently all approved strategies for GvHD treatment are immunosuppressive therapies, with the first-line therapy being glucocorticoids. However, therapeutic options for glucocorticoid-refractory patients are still limited. Novel therapeutic approaches, which reduce GvHD severity while preserving GvL activity, are urgently needed. Targeting kinase activity with small molecule inhibitors has shown promising results in preclinical animal models and clinical trials. Well-studied kinase targets in GvHD include Rho-associated coiled-coil-containing kinase 2 (ROCK2), spleen tyrosine kinase (SYK), Bruton’s tyrosine kinase (BTK) and interleukin-2-inducible T-cell kinase (ITK) to control B- and T-cell activation in acute and chronic GvHD. Janus Kinase 1 (JAK1) and 2 (JAK2) are among the most intensively studied kinases in GvHD due to their importance in cytokine production and inflammatory cell activation and migration. Here, we discuss the role of kinase inhibition as novel treatment strategies for acute and chronic GvHD after allo-HCT.
The Circadian Clock in Lepidoptera

With approximately 160,000 identified species of butterflies and moths, Lepidoptera are among the most species-rich and diverse insect orders. Lepidopteran insects have fundamental ecosystem functions as pollinators and valuable food sources for countless animals. Furthermore, Lepidoptera have a significant impact on the economy and global food security because many species in their larval stage are harmful pests of staple food crops. Moreover, domesticated species such as the silkworm Bombyx mori produce silk and silk byproducts that are utilized by the luxury textile, biomedical, and cosmetics sectors. Several Lepidoptera have been fundamental as model organisms for basic biological research, from formal genetics to evolutionary studies. Regarding chronobiology, in the 1970s, Truman’s seminal transplantation experiments on different lepidopteran species were the first to show that the circadian clock resides in the brain. With the implementation of molecular genetics, subsequent studies identified key differences in core components of the molecular circadian clock of Lepidoptera compared to the dipteran Drosophila melanogaster, the dominant insect species in chronobiological research. More recently, studies on the butterfly Danaus plexippus have been fundamental in characterizing the interplay between the circadian clock and navigation during the seasonal migration of this species. Moreover, the advent of Next Generation Omic technologies has resulted in the production of many publicly available datasets regarding circadian clocks in pest and beneficial Lepidoptera. This review presents an updated overview of the molecular and anatomical organization of the circadian clock in Lepidoptera. We report different behavioral circadian rhythms currently identified, focusing on the importance of the circadian clock in controlling developmental, mating and migration phenotypes. We then describe the ecological importance of circadian clocks detailing the complex interplay between the feeding behavior of these organisms and plants. Finally, we discuss how the characterization of these features could be useful in both pest control, and in optimizing rearing of beneficial Lepidoptera.
5 Years of Exercise Intervention Did Not Benefit Cognition Compared to the Physical Activity Guidelines in Older Adults, but Higher Cardiorespiratory Fitness Did. A Generation 100 Substudy

Background: Aerobic exercise is proposed to attenuate cognitive decline in aging. We investigated the effect of different aerobic exercise interventions and cardiorespiratory fitness (CRF) upon cognition throughout a 5-year exercise intervention in older adults. Methods: 106 older adults (52 women, age 70-77 years) were randomized into high-intensity interval training (HIIT; ∼90% peak heart rate), moderate-intensity continuous training (MICT; ∼70% peak heart rate), or control for 5 years. The HIIT and MICT groups performed supervised training twice weekly, while the control group was asked to follow the national physical activity guidelines (30 min of physical activity/day). At baseline, 1-, 3-, and 5-year follow-up, participants partook in cognitive testing (spatial memory, verbal memory, pattern separation, processing speed, working memory, and planning ability), underwent clinical testing, and filled out health-related questionnaires. Linear mixed models were used to assess the effects of the exercise group and CRF (measured as peak and max oxygen uptake) on each cognitive test. The effects of changes in CRF on changes in each cognitive test score throughout the intervention were also assessed. The associations between baseline CRF and cognitive abilities at the follow-ups were investigated using linear regressions. Results: There was no group-by-time interaction on the cognitive measures, and neither HIIT nor MICT participation was associated with better cognitive performance than control at any time point during the 5-year intervention. All groups increased their CRF similarly during the 1st year and subsequently declined back to baseline levels after 5 years. A higher CRF was associated with higher processing speed throughout the intervention while increasing CRF during the intervention was associated with better working memory and worse pattern separation. Higher CRF at baseline predicted consistently better processing speed and verbal memory performance. Conclusion: In this first 5-year randomized controlled trial investigating the effects of HIIT, MICT, and physical activity according to national guidelines on cognition, we observed no effect of exercise intervention group on cognition when compared to following the national physical activity guidelines. Still, the results showed that higher CRF and increasing CRF benefited multiple, but not all, cognitive abilities in older adults. Clinical Trial Registration: www.ClinicalTrials. gov, identifier [NCT01666340].