Miracle-dz/UniFAR-FTUs huggingface dataset:
How self-efficacy beliefs in dealing with negative emotions are associated to negative affect and to life satisfaction across gender and age

The present study examines the extent to which individuals’ self-efficacy beliefs about their capacity to manage distinct emotions, such as anger, sadness, fear, shame and guilt, are associated with negative affect and life satisfaction in a Spanish population of diverse ages. The results attest to the validity of the Multidimensional Negative Emotions Self-Regulatory Efficacy Scale (MNESRES) and show that self-efficacy beliefs related to basic and self-conscious/moral emotions are associated differently with negative affect and life satisfaction. These findings corroborate previous findings from American and Italian populations, and they support the view that discrete emotions deserve distinct attention, either regarding their management or their association with individuals’ well-being and adjustment.
The permeabilized SecY protein-translocation channel can serve as a nonspecific sugar transporter

As the initial step in carbohydrate catabolism in cells, the substrate-specific transporters via active transport and facilitated diffusion play a decisive role in passage of sugars through the plasma membrane into the cytoplasm. The SecY complex (SecYEG) in bacteria forms a membrane channel responsible for protein translocation. This work demonstrates that weakening the sealability of the SecY channel allowed free diffusion of sugars, including glucose, fructose, mannose, xylose, arabinose, and lactose, into the engineered cells, facilitating its rapid growth on a wide spectrum of monosaccharides and bypassing/reducing stereospecificity, transport saturation, competitive inhibition, and carbon catabolite repression (CCR), which are usually encountered with the specific sugar transporters. The SecY channel is structurally conserved in prokaryotes, thus it may be engineered to serve as a unique and universal transporter for bacteria to passage sugars as demonstrated in Escherichia coli and Clostridium acetobutylicum.
Tim-3 promotes cell aggressiveness and paclitaxel resistance through NF-κB/STAT3 signalling pathway in breast cancer cells

Objective Although T-cell immunoglobulin and mucin-domain containing molecule-3 (Tim-3) has been recognized as a promising target for cancer immunotherapy, its exact role in breast cancer has not been fully elucidated. Methods Tim-3 gene expression in breast cancer and its prognostic significance were analyzed. Associated mechanisms were then explored in vitro by establishing Tim-3-overexpressing breast cancer cells. Results In a pooled analysis of The Cancer Genome Atlas (TCGA) database, Tim-3 gene expression levels were significantly higher (P<0.001) in breast cancer tissue, compared with normal tissues. Tim-3 was a prognosis indicator in breast cancer patients [relapse-free survival (RFS), P=0.004; overall survival (OS), P=0.099]. Tim-3 overexpression in Tim-3low breast cancer cells promoted aggressiveness of breast cancer cells, as evidenced by enhanced proliferation, migration, invasion, tight junction deterioration and tumor-associated tubal formation. Tim-3 also enhanced cellular resistance to paclitaxel. Furthermore, Tim-3 exerted its function by activating the NF-κB/STAT3 signalling pathway and by regulating gene expression [cyclin D1 (CCND1), C-Myc, matrix metalloproteinase-1(MMP1), TWIST, vascular endothelial growth factor (VEGF) upregulation, concomitant with E-cadherin downregulation). Lastly, Tim-3 downregulated tight junction-associated molecules zona occludens (ZO)-2, ZO-1 and occludin, which may further facilitate tumor progression. Conclusions Tim-3 plays an oncogenic role in breast cancer and may represent a potential target for antitumor therapy.
Adaptive volumetric light and atmospheric scattering

An adaptive sampling-based atmospheric scattering and volumetric light framework for flight simulator (FS) is proposed to enhance the immersion and realism in real-time. The framework comprises epipolar sampling (ES), visible factor culling (VFC), interactive participating media density estimating (IPMDE). The main process of proposed architecture is as follows: the scene is divided into two levels according to the distance from the camera. In the high-level pipeline, the layer close to the camera, more samples, and smaller sampling step size is used to improve image quality. Further, the IPMDE method is designed to enhance realism by achieving interactivity with the participating media and multiple light sources. Further optimization is performed by the lookup table and 3D volumetric textures, by which we can compute the density of participating media and the scattering coefficient in parallel. In the low-level pipeline, when the samples are far away from the camera, its influence on the final output is also reduced, which results in fewer samples and a bigger sampling step size. The improved ES method further reduces the number of samples involved in ray marching using the features of epipolar geometry. It then generates global light effects and shadows of distant terrain. The VFC method uses an acceleration structure to quickly find the lit segments which eliminate samples blocked by obstacles. The experimental results demonstrate our architecture achieves a better sense of reality in real-time and is very suitable for FS.
Generation of scale-invariant sequential activity in linear recurrent networks

Sequential neural activity has been observed in many parts of the brain and has been proposed as a neural mechanism for memory. The natural world expresses temporal relationships at a wide range of scales. Because we cannot know the relevant scales a priori it is desirable that memory, and thus the generated sequences, are scale-invariant. Although recurrent neural network models have been proposed as a mechanism for generating sequences, the requirements for scale-invariant sequences are not known. This paper reports the constraints that enable a linear recurrent neural network model to generate scale-invariant sequential activity. A straightforward eigendecomposition analysis results in two independent conditions that are required for scaleinvariance for connectivity matrices with real, distinct eigenvalues. First, the eigenvalues of the network must be geometrically spaced. Second, the eigenvectors must be related to one another via translation. These constraints are easily generalizable for matrices that have complex and distinct eigenvalues. Analogous albeit less compact constraints hold for matrices with degenerate eigenvalues. These constraints, along with considerations on initial conditions, provide a general recipe to build linear recurrent neural networks that support scale-invariant sequential activity.
Long-Term Inhibition of Rho-Kinase Suppresses Angiotensin II–Induced Cardiovascular Hypertrophy in Rats In Vivo

Intracellular signaling pathway mediated by small GTPase Rho and its effector Rho-kinase plays an important role in regulation of vascular smooth muscle contraction and other cellular functions. We have recently demonstrated that Rho-kinase is substantially involved in angiotensin II–induced gene expressions and various cellular responses in vitro. However, it remains to be examined whether Rho-kinase is involved in the angiotensin II–induced cardiovascular hypertrophy in vivo and, if so, what mechanisms are involved. Long-term infusion of angiotensin II for 4 weeks caused hypertrophic changes of vascular smooth muscle and cardiomyocytes in rats. Both changes were significantly suppressed by concomitant oral treatment with fasudil, which is metabolized to a specific Rho-kinase inhibitor, hydroxyfasudil, after oral administration. Angiotensin II caused a perivascular accumulation of macrophages and Rho-kinase activation, both of which were also significantly suppressed by fasudil. Vascular NAD(P)H oxidase .
Thermal regime drives a latitudinal gradient in morphology and life history in a livebearing fish

1School of Biological Sciences, Royal Holloway, University of London, Egham, Surrey TW20 0EX, UK 2Department of Biology, Case Western Reserve University, Cleveland, OH 44106, USA 3Department of River Ecology and Conservation, Senckenberg Research Institute and Natural History Museum Frankfurt, Gelnhausen, Germany 4College of Animal Science and Technology, Northwest A&F University, Yangling, Shaanxi 712100, PR China 5Department of Biological Sciences & W. M. Keck Center for Behavioral Biology, North Carolina State University, 127 David Clark Labs, Raleigh, NC 27695-7617, USA
The complete chloroplast genome of Pyrrosia bonii (Polypodiaceae), an important ornamental and medical fern

Abstract Pyrrosia bonii is an important ornamental and medical fern from Polypodiaceae. Its complete chloroplast genome sequence was characterized through de novo assembly with Illumina sequencing data. The genome size is 158,174 bp, with large single copy (LSC, 82,479 bp) and small single copy (SSC, 21,723 bp) regions separated by a pair of inverted repeats (IR, 26,986 bp). A total of 132 genes were identified, including 88 protein coding genes, 35 tRNA genes, eight rRNA genes, and one pseudogene. Maximum-likelihood phylogenetic tree revealed that P. bonii was most closely related to Lepisorus clathratus. The study will greatly facilitate the chloroplast phylogenomics of Polypodiaceae.
Management of penoxsulam- and bispyribac-resistant late watergrass ( Echinochloa phyllopogon ) biotypes and rice sedge ( Cyperus difformis ) in rice

The repeated use of herbicides with the same mode of action maybe has led to buildup of resistant late watergrass (Echinochloa phyllopogon (Stapf) Stapf ex Kossenko) populations. Thus, pot experiment was conducted to evaluate the level of penoxsulamand bispyribac-resistance in seven late watergrass biotypes collected from water-seeded rice fields in Greece. Their susceptibility to imazamox and profoxydim was also studied. Furthermore, the efficacy of various herbicide combinations against the resistant late watergrass biotypes, as well as on rice sedge (Cyperus difformis L.) were evaluated in four field experiments. In pot experiment, two biotypes were resistant to both herbicides, while three biotypes were moderately resistant to penoxsulam with one of these simultaneously resistant to bispyribac. Four biotypes were also cross-resistant to imazamox, while all biotypes were susceptible to profoxydim. In field experiments, the double applications of penoxsulam or bispyribac applied at 18 d after seeding (DAS) followed by profoxydim plus halosulfuron at 35 DAS constantly provided the greatest rice yield and satisfactory control of both weeds. Conclusively, late watergrass resistant to penoxsulam and bispyribac biotypes have been built. In particular, rates up to 8 times the recommended rate did not provide acceptable weed control. Effective control of these biotypes and high rice yield can be achieved by double applications of herbicides with different modes of action (penoxsulam or bispyribac until the third leaf of rice [18 DAS] followed by profoxydim at seven-to eight-leaves growth stage [35 DAS]). Simultaneous control of late emerged rice sedge can be achieved by the addition of halosulfuron in the tank-mix with profoxydim.
Phytophthora Infestans: Isolation of Pure Cultures, Storage and Inoculum Preparation

Abstract Phytophthora infestans causes potato and tomato late blight, economically the most important disease of these plant species. The Oomycete pathogen is frequently sampled, isolated to pure cultures, stored, and characterized. The knowledge of its diversity, migrations and evolution is essential for breeding resistant plants and for designing appropriate control strategies. The article presents methods for collection, storage and preparation of P. infestans isolates for inoculation of plant tissues, based on the publication by Zarzycka (2001), later updated and modified.
Development of positive discharge in meter-scale STP air gap

We investigated the development of negative long laboratory discharge powered by a Marx generator of 1 MV in STP air gap of 1.27 meter. We present its evolution with nanosecond-fast photography together with electrical characteristics and x-ray measurement. Negative discharge develops via formation of space stem structures and possesses step-like propagation. As in positive discharge we observe streamer encounters at x-ray time. Difference between positive and negative discharge development and x-ray production is discussed.
An imaging-genetic study of the asymmetries in the temporal lobe structures : association of these human-specific markers of development with genetics

The asymmetrical structure of the temporal lobe has already been demonstrated. These structural asymmetries are often assumed to contribute to the human language lateralization. One noticeable asymmetry is the one of the superior temporal sulcus (STS) depth observed from birth in humans, but not in chimpanzee. In this thesis, we were interested in the genetic roots underlying this asymmetry. To this aim, we used automated extraction method of asymmetrical structures such as the sulcal roots or transverse gyri (so called plis de passage, PPs). First, we reproduced the STS rightward depth asymmetry in two large cohorts (HCP and UK Biobank) and we demonstrated that the left STS is more often interrupted by a PP than its counterpart. Second, the heritability estimates of depth and convexity of sulcal roots in the STS and the presence of PP are higher in the left hemisphere. This suggests asymmetric genetic cues contributing to the formation of these asymmetrical structures in the temporal lobe. In addition, we have shown that the functional activations in the angular gyrus have a significant shared genetic variance with the human cognitive performance. Finally, we have identified a cis-regulating region of the KCNK2, as being significantly associated with the width and cortical thickness of the brain sulci, which are features of brain ageing.
Genotypic Correlation Coefficient Analysis of Different Characters in Carrot Genotypes (Daucus carota L.) under Kharif Season

Carrot (Daucus carota L.) is most important root crop worldwide nutritionally and as a protective food, because it is a rich source of β-carotene, fiber and other dietary nutrients (Simon, 1990). Carrot is the most economically important vegetable crop worldwide (Simon et al., 2008) and it is the most widely cultivated vegetable among the vegetables of the Apiaceae family (Rubatzky et al., 1999). It belongs to the family Umbelliferae (Apiaceae) and having a chromosome number 2n=18. Carrot is originated from Southwestern Asia, especially Afghanistan (Banga, 1976). It is a popular cool season vegetable. In temperate region, it is cultivated during spring and summer season, while in tropical region during winter season. It is grown as biennial for seed production and annual for its roots. In India, carrot is mainly cultivated in the states of Haryana, Punjab, Uttar Pradesh, Karnataka and Tamil Nadu. In Karnataka, carrot is mainly cultivated in the districts of Kolar, Chikkaballapur, Belagavi, Bengaluru Rural, Gulbarga and Bidar. The nutritional composition of carrot roots are moisture (88.8%), protein (0.7%), carbohydrates (6%), total sugars (5.6%), carotene (5.33 mg), fiber (2.4%) and vitamin C (4 mg) per 100 g edible portion (Sharma et al., 2012). It also contains International Journal of Current Microbiology and Applied Sciences ISSN: 2319-7706 Volume 7 Number 09 (2018) Journal homepage: http://www.ijcmas. com
Information Security Investment and Security Breach: Empirical Study on the Reverse Causality

본 연구는 2010년 한국인터넷진흥원에서 조사한 “기업의 정보보호 실태조사”의 원자료를 패널데이터로 재구성하여 정보보호 투자와 침해사고의 인과관계를 분석하였다. 이중차분법을 이용하여 분석한 실증결과는 다음과 같다. 첫째, 정보보호투자가 침해사고를 줄인다는 통상적인 인과관계에 대해서는 유의미한 실증적인 근거를 발견하기 어려웠던 반면, 역의 인과관계, 즉 침해사고가 많은 기업이 정보보호 투자를 증가시킨다는 가설은 유의미하게 데이터에 의해 입증되는 것으로 나타났다. 둘째, 정보보호에 매우 민감하기 때문에 다른 업종에 비해 과감한 사전적인 투자를 수행하는 것으로 인식되고 있는 금융/보험업의 경우, 실증분석에 따르면 오히려 침해사고의 발생에 따라 사후적으로 정보보호 투자를 수행하고 있는 대표적인 업종으로 나타났다.
Apoio à negociação conceptual com base em processos híbridos de avaliação de similaridade semântica

A modelacao conceptual permite que especialistas descrevam um determinado dominio em estruturas do tipo conceito - relacao - conceito. Num ambiente colaborativo, para um mesmo dominio, um processo de conceptualizacao pode originar varias solucoes. E necessario que os participantes cheguem a um consenso que represente uma solucao partilhada. O foco principal deste trabalho situa-se nesta etapa. Pretendemos criar uma nova abordagem para integracao de estruturas conceptuais de diferentes modelos, facilitando assim o processo de negociacao. Para tal, este trabalho recorre a utilizacao de algoritmos de similaridade semântica.
Evaluation of the influences of dam release types, land use, and habitat affecting abundance, richness, diversity, and community structure of larval and juvenile fish

We systematically evaluated the influence of dams on downstream aquatic habitat and early life stage (ELS) fish at two spatial scales from epilimnetic and hypolimnetic discharges and made comparisons with a control stream. ELS fish exhibited a general increase in abundance, richness, and Shannon diversity with increasing distance from dams in both epilimnetic and hypolimnetic release types. Nonmetric multidimensional scaling (NMDS) indicated larval and juvenile fish communities were structured differently between epilimnetic and hypolimnetic releases, and habitat variables structuring those communities were more variable in epilimnetic releases than in hypolimnetic releases. Rapid changes occurred within the first 1100 m reach and a second more gradual gradient extended beyond the 5100 m sample reach. Generally, our findings agreed with that of the Serial Discontinuity Concept (SDC), but we believe future studies should be explicit in the systematic evaluation of the SDC, and further studies are required to understand the two recovery gradients that exist below impoundments.
Comparisons of sets of electron–neutral scattering cross sections and swarm parameters in noble gases: III. Krypton and xenon

This paper, the third in a series of three, describes work carried in the context of Plasma Data Exchange Project of the Gaseous Electronics Conference (PDEP-GEC) to compare electron collision cross-sections sets from ground-state, noble gases atoms and to check their consistency with measured swarm parameters. Such consistency is a minimum requirement if the cross-section data are to be used for modelling low-temperature plasmas. In this paper, we present intercomparisons of the independently compiled sets of electron cross-sections from ground-state, neutral Kr and Xe atoms presently available on the LXCat open-access website (www.lxcat.laplace.univ-tlse.fr). Swarm parameters (reduced mobility, characteristic energy, reduced longitudinal diffusion coefficient, reduced ionization coefficient) calculated in a Boltzmann solver or Monte Carlo simulation using these cross-sections sets are compared with experimental data, also available online on the LXCat site.
Molecular Markers Highlight Variation within and among Kentucky Bluegrass Varieties and Accessions

All rights reserved. No part of this periodical may be reproduced or transmitted in any form or by any means, electronic or mechanical, including photocopying, recording, or any information storage and retrieval system, without permission in writing from the publisher. Permission for printing and for reprinting the material contained herein has been obtained by the publisher. Molecular Markers Highlight Variation within and among Kentucky Bluegrass Varieties and Accessions B. Shaun Bushman, Scott E. Warnke, Keenan L. Amundsen, Kathleen M. Combs, and Paul G. Johnson
Proceedings of the Fourth International Workshop on Mathematical Foundations of Computational Anatomy - Geometrical and Statistical Methods for Biological Shape Variability Modeling (MFCA 2013), Nagoya, Japan

Computational anatomy is an emerging discipline at the interface of geometry, statistics and image analysis which aims at modeling and analyzing the biological shape of tissues and organs. The goal is to estimate representative organ anatomies across diseases, populations, species or ages, to model the organ development across time (growth or aging), to establish their variability, and to correlate this variability information with other functional, genetic or structural information. The Mathematical Foundations of Computational Anatomy (MFCA) workshop aims at fostering the interactions between the mathematical community around shapes and the MICCAI community in view of computational anatomy applications. It targets more particularly researchers investigating the combination of statistical and geometrical aspects in the modeling of the variability of biological shapes. The workshop is a forum for the exchange of the theoretical ideas and aims at being a source of inspiration for new methodological developments in computational anatomy. A special emphasis is put on theoretical developments, applications and results being welcomed as illustrations. Following the first edition of this workshop in 2006, second edition in New-York in 2008, the third edition in Toronto in 2011, the forth edition was held in Nagoya Japan on September 22 2013.
A System Biology Approach to Identify the Genetic Markers to the progression of Parkinson's disease for Aging, lifestyle and Type 2 Diabetes

Actual causes of Parkinson9s disease (PD) are still unknown. In any case, a better comprehension of genetic and ecological influences to the PD and their interaction will assist physicians and patients to evaluate individual hazard for the PD, and definitely, there will be a possibility to find a way to reduce the progression of the PD. We introduced quantitative frameworks to reveal the complex relationship of various biasing genetic factors for the PD. In this study, we analyzed gene expression microarray data from the PD, ageing (AG), severe alcohol consumption (AC), type II diabetes (T2D), high body fat (HBF), hypercholesterolemia (HC), high dietary fat (HDF), red meat dietary (RMD), sedentary lifestyle (SL), smoking (SM), and control datasets. We have developed genetic associations of various factors with the PD based on the neighbourhood-based benchmarking and multilayer network topology. We identified 1343 significantly dysregulated genes in the PD patients compared to the healthy control, where we have 779 genes down-regulated and 544 genes up-regulated. 69 genes were highly expressed in both for the PD and alcohol consumption whereas the number of shared genes for the PD and the type II diabetes is 51. However, the PD shared 45, 43 and 42 significantly expressed genes with the ageing, high dietary fat and high body fat respectively. The PD shared less than 40 significant transcripts with other factors. Ontological and pathway analyses have identified significant gene ontology and molecular pathways that enhance our understanding of the fundamental molecular procedure of the PD progression. Therapeutic targets of the PD could be developed using these identified target genes, ontologies and pathways. Our formulated methodologies demonstrate a network-based approach to understand the disease mechanism and the causative reason of the PD, and the identification for therapeutic targets of the PD.