Miracle-dz/UniFAR-FTUs huggingface dataset:
Kamisetti and Gupta: Solubility Enhancement of Ebastine by Self-Nanoemulsifying Delivery Strategy

The aim of the study was to develop and optimize Selfnanoemulsifying drug delivery systems (SNEDDS) for the improvement of solubility and dissolution of an anti-allergic drug, Ebastine, a BCS class II drug. Preliminary screening was carried out to select proper components combination of Oil (Oleic acid): Surfactant (Tween® 80): Co-solvent (Ethanol). Pseudo-ternary phase diagram experimental design was applied to formulate and optimize the SNEDDS containing 3:7 of (oil: S mix ). Drug-Excipient compatibility studies were performed by FTIR and found no chemical interaction between the drug and excipients. The systems were assessed for evaluation parameters like optical clarity in three stages by exposing the SNEDDS to heatingcooling cycle at 4 to 45 oC, centrifugation at 5000rpm and freeze-thaw cycles at -21 oC to 21 oC. The droplets of optimized SNEDDS formulation were found to be spherical with a size range of 76-111nm and emulsification efficiency of 97.67 ± 0.3% and 91.1 ± 0.06% drug release at the end of 30 minutes with a significant increase in dissolution rate compared to the marketed drug suspension under the same conditions. The optimized SNEDDS formulation charged for the accelerated stability studies at 40 oC/75% RH for three months revealed to be stable with 95.31 ± 1.4% drug content and 90.12 ± 1.98% drug release. It was hence concluded that the solubility of poorly soluble drugs like Ebastine can be effectively enhanced using Self nano emulsifying approaches with the use of Oleic acid, Tween 80 and Ethanol as Oil, surfactant and co-solvent respectively.
Online monitoring and control of the biogas process

Copyright and moral rights for the publications made accessible in the public portal are retained by the authors and/or other copyright owners and it is a condition of accessing publications that users recognise and abide by the legal requirements associated with these rights.  Users may download and print one copy of any publication from the public portal for the purpose of private study or research.  You may not further distribute the material or use it for any profit-making activity or commercial gain  You may freely distribute the URL identifying the publication in the public portal If you believe that this document breaches copyright please contact us providing details, and we will remove access to the work immediately and investigate your claim. Downloaded from orbit.dtu. dk on: Nov 10, 2019
Feasibility of Using Telephone, Association, and Licensure Directories to Examine the Geographic Distribution of Naturopathic Physicians in Oregon, Arizona, and Connecticut

Address information from the Yellow Pages and the American Association of Naturopathic Physicians (AANP) is too incomplete to map distributions of naturopathic physicians (N.D.’s). Although these sources are incomplete, their address fields contain business addresses which can be used to confirm or augment uncertain address fields in state licensure databases. The researchers compiled lists of N.D. ’s from the Yellow Pages and the AANP. Names and names and addresses from these sources were matched to state licensure databases for Oregon, Arizona, and Connecticut. Next they used the Yellow Pages and AANP to confirm business addresses or replace suspected residential addresses in state licensure databases. Because of the availability of phone numbers contained within the licensure database for Arizona, a telephone survey of N.D. ’s was conducted to estimate the remaining number of unconfirmed addresses for this state. Finally, the researchers combined address information from state licensure databases, Yellow Pages, and AANP directories to develop enhanced geographic databases that were used to produce proportional symbol maps of N.D. locations in Oregon, Arizona, and Connecticut. The largest number of matches occurred using a combination of AANP and Yellow Pages directories. Oregon had the best percent of business addresses (93%) without having to use outside address sources. Using AANP, the Yellow Pages, and survey estimates, 89% of Arizona’s state licensure address records were confirmed as business locations. Sixty-eight percent of Connecticut’s licensure address records were confirmed as business locations using the AANP and Yellow Pages directories. The Yellow Pages and AANP directories are not appropriate separately or in combination to produce a geographic database. These sources were incomplete; nevertheless, such directories were useful in confirming state licensure addresses when it is unknown whether the addresses listed by the licensing authorities represent residential or
Characteristics of ionospheric irregularities 1 near the north EIA at 121 ° E 2

Jinghua Li 1 , Guanyi Ma 1,2 , Klemens Hocke 3,4 , Qingtao Wan 1 , Jiangtao Fan 1 , Xiaolan Wang 1 3 1 National Astronomical Observatories, Chinese Academy of Sciences, Beijing, China. 4 2 University of Chinese Academy of Sciences, Beijing, China. 5 3 Institute of Applied Physics, University of Bern, Bern, Switzerland 6 4 Oeschger Centre for Climate Change Research, University of Bern, Bern, Switzerland 7
Incubation Process and Entrepreneurial Characteristics : An Interactive Perspective

The following work was performed at the technological incubator in Santa Maria, Brazil (ITSM), aiming to analyze the influence of the incubation process on entrepreneurial characteristics and apprenticeship, in the view of business managers who experience this process at ITSM. To that end, data were collected through semi-structured interviews with eight managers of incubated businesses and documental research. The questions addressed in the interview focused on life story, professional career, incubation process and entrepreneur apprenticeship, the latter, following the propositions by Politis (2005). At the same time, the questionnaire developed by David McClelland (1972) on Entrepreneurial Behavior Characteristics (EBC) was applied. For data analysis, the method of content analysis of interview was used, based on Bardin (2011). The categories of analysis defined a priori were: incubation process, entrepreneurial characteristics, and entrepreneurial apprenticeship. The categories of analysis not defined a priori and based on the reports of interviewees were: perceived demands and interaction needs. The objective of the study was fully achieved, considering that, from the perspective of the incubated subjects, ITSM allowed opportunities for these individuals as well as their businesses to develop, stimulating their learning through an experiential nature. From the results obtained, a plan of action was designed for ITSM aiming to reduce the demands observed by the incubated individuals regarding the incubation process.
(k, q)-trace norm for sparse matrix factorization

We propose a new convex formulation for the sparse matrix factorization problem, where the number of nonzero elements of the factors is fixed. An example is the problem of sparse principal component analysis, which we reformulate as a proximal operator computation through the definition of new matrix norms that can be used more generally as regularizers for various optimization problems over matrices. We estimate the Gaussian complexity for the suggested norms and their vector analogues. Surprisingly, in the matrix case, knowing in advance the blocks size improves the statistical power of the norms by an order of magnitude compared to the usual `1 and trace norms, whereas in the vector case the norms built using the knowledge of the number of nonzeros have the same complexity as the `1 norm.
Modeling and Optimal LQG Controller Design for a Quadrotor UAV

This paper deals with the modeling and optimal Linear Quadratic Gaussian (LQG) controller design for a Quadrotor Vertical Take-Off and Landing (VTOL) type of Unmanned Aerial Vehicle (UAV). Such a LQG-based control strategy is investigated to stabilize the attitude and altitude dynamics of the studied Quad rotorcraft. All aerodynamic forces and moments of the Quadrotor UAV are described within an inertial frame and a dynamical model is obtained thanks to the Newton-Euler formalism. An optimal LQG controller is then designed for the attitude and altitude stabilization of the plant, linearized around an equilibrium flight point. Several simulation results are carried out in order to show the effectiveness and robustness of the proposed LQG-based flight stabilization approach. Keywords-: Quadrotor UAV, modeling, optimal LQG control, attitude and altitude stabilization.
Analysis of 3D Planar Cracks with Consideration of Surface Stress Effects

An efficient numerical procedure for modeling planar cracks in three-dimensional, linear elastic, infinite media accounting for the surface stress effect is presented in this paper. The concept of surface stresses, which has been widely employed in the modeling of nano-scale problems, is considered in the present study to derive a suitable mathematical model capable of simulating nano-sized cracks. An infinitesimally thin layer of material on the crack surface is modeled by a surface with zero-thickness and perfectly adhered to the bulk material, with its behavior governed by the Gurtin-Murdoch constitutive law. In the formulation, the classical theory of isotropic linear elasticity is utilized to establish the governing equation of the bulk material in terms of completely regularized boundary integral equations for the displacements and tractions on the crack surface. For the zero-thickness layer, the final governing equation incorporating the surface stress effect is obtained in a weak form following the standard weighted residual technique. Solutions of the fully coupled system of equations are then obtained by the FEM-SGBEM coupling numerical procedure. Owing to the weakly singular feature of all involved boundary integral equations, standard C 0
Recent Development and Evaluation for Effective Diagnosis and Treatment of Human Onchocerciasis, Using an Antigen Detection Dipstick Techniques: A Review

Onchocerciasis still remains a major hindrance to sustainable public health, farming and livestock development. However, the type of diagnostic test used for the detection of infections caused by onchocerciasis varies according to the epidemiological characteristics of the disease and the strategy for control. The clinical signs are not pathognomonic and the standard techniques for the detection of onchocerca species are not sufficiently sensitive. Despite several improvements in the techniques for onchocerca species detection, a high proportion of infections still go undetected as the majority of infections are chronic. This diagnostic challenge has led to the development of alternative methods, for instance molecular techniques, because they are extremely sensitive and better diagnostic tools. This write-up therefore, underscores the relevance of various diagnostic techniques in the epidemiological study of onchocerciasis. It concluded that, these current techniques can allow the investigation of the phylogeny and diversity of onchocerciasis species that would help in devising appropriate control measures to limit the public health and the economic losses arising from the disease.
THE EFFECTIVENESS OF HUMAN PATIENT SIMULATION ON BACCALAUREATE NURSING STUDENTS' TRANSFER OF LEARNING

ii ABSTRACT Nursing faculty members are utilizing interactive teaching tools to improve nursing student's critical decision-making skills; one method that has been found to be potentially effective is human patient simulation (HPS). The purpose of this time series design study was to determine whether undergraduate nursing students were able to transfer knowledge and skills learned from classroom lecture and a HPS clinical to the traditional clinical setting. Over the course of a semester, students were observed prior to a respiratory lecture, following the respiratory lecture, and following a simulation clinical. The researcher collected quantitative data to assess participants during specific points of their instruction to determine if transfer of learning had taken place. Participants included were entry level nursing students. The findings indicated that students were able to transfer knowledge and skills learned from the HPS setting to the traditional clinical setting. An assessment rubric was also used to determine clinical competence in the traditional clinical setting. The results provided evidence that students' perceived clinical competence and actual clinical competence was enhanced following HPS clinical. Results of the study also demonstrated that there was a positive correlation between students' self-perception of clinical competence and their actual competence following HPS clinical. iii DEDICATION " I can do all things through Christ who strengthens me. " Philippians 4:13 This dissertation is dedicated to my husband, Dr. Eric Kirkman. Thank you for being my mentor. I love you. This dissertation is also dedicated to my children Jalen and Justin Kirkman. You can do all things with self-discipline, tenacity, and faith in Christ. I wanted to complete this process because it is important for me to lead by example. I want the two of you to set your goals high and have the determination to reach for them. I love you with all my heart and hope that one day your aspirations will become reality. May the Lord grant you the desires of your heart and make all of your plans succeed (Psalms 20:4).
Dietary patterns and Metabolic Syndrome in adults.

Aims: Considering that diet is a potential factor contributing to the development of Metabolic Syndrome (MetS) and it is increasingly prevalent among population worldwide, the aim of the present study was to correlate dietary patterns with MetS and its main risk factors in adults. Study Design: Cross-sectional. Place and Duration of Study: School of Public Health, University of Sao Paulo, between August 2007 and January 2010. Methodology: This study was conducted with 267 adults (189 women and 78 men) submitted to evaluation procedures which included body composition (waist circumference (WC), height and weight) and blood pressure measurements, biochemical analysis from a single blood sample after a 12-h fasting (serum triglycerides (TG), total cholesterol (TC), low-density lipoprotein cholesterol (LDL-c), high-density lipoprotein cholesterol (HDL-c) and fasting glucose) and assessment of dietary intake using a 24-hour recall. Dietary patterns (DPs) were identified using principal components factor analysis with varimax orthogonal rotation. Results: Three distinct DPs were identified from the principal component factor analysis: “Traditional”, “Healthy” and “Western”. Among individuals with MetS, there was a positive correlation between Healthy pattern and HDL-c (P = .03), as well as between Western pattern and WC, TG and LDL-c (P = .001, P = .04 and P = .047). In people without MetS, the negative correlation was observed between Traditional pattern and LDL-c (P = .049), and positive correlation between Healthy pattern and age, TC and, LDL-c (P = .01, P = .03 and P = .03). Conclusion: Our assessment offers information concerning food combinations that may increase the risk and prevalence of MetS. However, more studies are required to confirm these findings and Short Research Article Oliveira et al.; EJNFS, 5(4): 297-304, 2015; Article no.EJNFS. 2015.027 298 to assist in the prevention and development of specific nutritional recommendations for this syndrome.
Peptides obtained from proteins of cobia ( Rachycentron canadum ) : A study of potentially safe antioxidants for food

The fish and its by-products from industrial processing are a rich source of protein. For this reason, cobia (Rachycentron canadum), a large and easily adaptable to aquaculture species has emerged as an option for obtaining peptides. Enzymatic proteolysis is able to release inactive biopeptides – which may have greater activity when separated into their peptide fractions – from intact proteins. However, as they can be applied in food, they should be evaluated for any possible harm to health. Thus, this study aimed to evaluate the ability of the protein hydrolysates of cobia (muscle and waste), obtained by the action of Alcalase, Flavourzyme and Protamex enzymes (whole and their fractions less and major than 3 kDa) to inhibit the oxidation of meat food and ensure their food security. The hydrolysates studied in this work demonstrated antioxidant activity through chemical methods in vitro. All hydrolysates and their fractions were not cytotoxic to zebrafish (Danio rerio) hepatocytes at the concentrations of 0.1, 1.0, 10 and 100 μg/mL at 0, 24, 48 and 72 h. By determining the inhibition of thiobarbituric acid reactive substances in bacon and ground beef it was found that the majority of the hydrolysates presented this capacity, highlighting the peptide fractions major than 3 kDa of muscle hydrolysates which reduced by around 50% the TBARS (thiobarbituric acid reactive substances) content formed in the ground beef, and by more than 80% in bacon, probably because the bacon has a higher content of lipid. The enzyme Protamex provided hydrolyzed with more antioxidant activity. Therefore, these results indicate that the hydrolysates studied have the potential to be safe physicochemically, not cytotoxic, used in foods as antioxidants.
INFLUENCE OF SOME TRACE MINERALS IN FORM OF NANO PARTICLES AS FEED ADDITIVES ON LAMBS PERFORMANCE.

This study was carried out to investigate the effect of large particles (zinc Zn or selenium SE ) or nano-Zn and nano-Se particles as feed supplement in lambs rations on feed intake, degradability, growth performance and some blood parameters. Twenty five growing lambs aging about 5-6 months with average body weight of 24.5kg, were used. Lambs were divided into five similar groups and fed randomly on one of the following rations. The first group received the basal ration, composed of concentrate feed mixture (CFM) to cover 50% of protein and energy allowances recommended by NRC (1989) and clover hay (CH) without feed additives which served as the control group (R1). The other tested groups were randomly fed the control ration supplemented with 10 mg large particles zinc (L-Zn), 0.04 mg large particles selenium (L-Se), 5 mg nano particles zinc (N-Zn) and 0.02 mg nano particles selenium (N-Se) / kg CFM for rations R2,R3, R4 and R5, respectively. Two canulated sheep were used to measure in sacco disappearance of DM, OM and CP of tested rations. Results showed that N-Zn & N-Se particles groups improved DM, OM and CP degradability compared with control group. But there were no significant differences among large particles groups and control group. Ration contained N-Zn had a significant effect on DM intake, but there were no significant differences among the large particles zinc (L-Zn) or selenium (L-Se) groups and control group among DMI. On the meantime, results showed that R4 & R5 groups increased (P<0.05) average daily gain and total weight gain compared to the control group. Also, feed conversation as DMI/ kg gain for R4 & R5 groups were improved by 16.93 and 18.25%, as compared with control group. Feed cost /kg gain was decreased for R4 and R5 groups as compared with control group. Serum total protein and albumin for R4 was increased compared with control group. While no significant differences between control group and other groups were found among AST and ALT values. In conclusion, large size particles of Zn or Se could be replaced with smaller amount of nano particles Zn or Se without any side effects on the animal performance.
Lateral Flow Assay for Salmonella Detection and Potential Reagents

Salmonella is among the very important pathogens threating human and animal health. It is a common food pathogen transmitted from animals to humans via contaminated food, drinking water, and air. It invades the intestinal tract of hosts and causes salmonellosis leading to death. S. enteritidis was the most common species accounted for all salmonellosis cases. S. typhimurium is also another significant species causing the serious cases worldwide. To ensure public health, early detection of pathogens is crucial. Lateral flow assay (LFA), immunochromatographic assay, is a simple and rapid diagnostic test kits used in various fields and can be developed by, aptamers, antibodies (Abs), and nucleic acids. They are also being continued to develop different capture reagents coming from the recombinant technology. It has many advantages such as having mature technology, market presence, low cost, easy to use for end users without education, and stable shelf life. Gold nanoparticles (GNPs) are the most commonly used labels in the LFAs for the naked-eye analysis. Therefore, Salmonella detection by LFA based on GNPs in a rapid and simple way is always open to be developed by new reagents and methods.
Self-Supervised Deep Depth Denoising (Supplementary Material)

In this supplementary material we complement our original manuscript with additional quantitative and qualitative results, which better showcase the advantages of the proposed self-supervised denoising model over traditional filtering and supervised CNN-based approaches. In particular, we present the adopted implementation details used for training our model, as well as additional qualitative results for the two 3D application experiments presented in the original manuscript, namely 3D scanning with KinectFusion [8] and full-body 3D reconstructions using Poisson 3D surface reconstruction [4]. A comparative evaluation with the learning-based state-of-the-art methods on InteriorNet (IN) [7] follows, while an ablation study concludes the document. The aforementioned results based on all methods presented in the originally manuscript, namely Bilateral Filter (BF [10]), Joint Bilateral Filter (JBF [6]), Rolling Guidance (RGF [12]), and data-driven approaches (DRR [3], DDRNet [11]). Note that for the DRR and DDRNet methods, additional results aim to highlight the over-smoothing effect of the former and the weakness of the latter to denoise depth maps captured by the Intel RealSense D415 sensors. In more detail, DRR is trained on static scenes that contain dominant planar surfaces and, thus tends to flatten (i.e. oversmooth) the input data. On the other hand, the available DDRNet model 1 that we used, produces high levels of flying pixels (i.e. spraying, see Fig. 1) which can be attributed to background (zero depth values) and foreground blending, even though its predictions are appropriately masked. While the authors have not provided the necessary information, it is our speculation that the available model is trained using Kinect 1 data, which is partly supported by the suboptimal results it produces on Kinect 2 data. Qualitatively, the remaining traditional filters (BF, JBF, RGF) perform similarly, with RGF showcasing the most competitive results to our method. However, note that
Hierarchical Super-Resolution-Based Inpainting

This introduces a new structure of exemplarbased inpainting. In this we combine both, inpainting method and super resolution method. With the help of this approach that high resolution image is converted to low-resolution image and inpainted then again converted into high-resolution image. This makes it easy both in terms of computational complexity and visual quality and work with the border of image structures. In Hierarchical Super-resolution method first select the area of image which has to be edited.Selected area within boundary will be filled by different colour. If image is in the form of high resolution then convert it into low resolution image. The low-resolution input picture is divided in patch of small size and inpainted one by one with the nearest neighbour pixel value. Patch will select accordingly the patch priority now the Inpainting outcome is again converted to high resolution image efficiently recovered by a single-image super-resolution algorithm.