Miracle-dz/UniFAR-FTUs huggingface dataset:
Roles and student identities in online large course forums: Implications for practice

The use of large online discussion forums within online and distance learning continues to grow. Recent innovations in online learning such as the MOOC (massive open online course) and concomitant growth in the use of online media for the delivery of courses in traditional campus based universities provide both opportunity and challenge for online tutors and learners alike. The recognition of the role that online tutors and student identity plays in the field of retention and progression of distance learners is also well documented in the field of distance learning. Focusing on a course forum linked to a single Level 2 undergraduate module and open to over 1,000 students, this ideographic case study, set in a large distance learning university, uses qualitative methodology to examine the extent to which participation in a large forum can be considered within community of practice (COP) frameworks and contributes to feelings of efficacy, student identity, and motivation. The paper draws on current theory pertaining to online communities and examines this in relation to the extent to which the forum adds to feelings of academic and social integration. The study concludes that although the large forum environment facilitates a certain degree of academic integration and identity there is evidence that it also presents a number of barriers producing negative effects on student motivation and online identity.
Visual Menu Techniques

Menus are used for exploring and selecting commands in interactive applications. They are widespread in current systems and used by a large variety of users. As a consequence, they have motivated many studies in Human-Computer Interaction (HCI). Facing the large variety of menus, it is difficult to have a clear understanding of the design possibilities and to ascertain their similarities and differences. In this article, we address a main challenge of menu design: the need to characterize the design space of menus. To do this, we propose a taxonomy of menu properties that structures existing work on visual menus. As properties have an impact on the performance of the menu, we start by refining performance through a list of quality criteria and by reviewing existing analytical and empirical methods for quality evaluation. This taxonomy of menu properties is a step toward the elaboration of advanced predictive models of menu performance and the optimization of menus. A key point of this work is to focus both on menus and on the properties of menus, and then enable a fine-grained analysis in terms of performance.
Augmenting Feedforward Models with Top-Down Feedback

Deva Ramanan CMU 540 541 542 543 544 545 546 547 548 549 550 551 552 553 554 555 556 557 558 559 560 561 562 563 564 565 566 567 568 569 570 571 572 573 574 575 576 577 578 579 580 581 582 583 584 585 586 587 588 589 590 591 592 593 594 595 596 597 598 599 600 601 602 603 604 605 606 607 608 609 610 611 612 613 614 615 616 617 618 619 620 621 622 623 624 625 626 627 628 629 630 631 632 633 634 635 636 637 638 639 640 641 642 643 644 645 646 647 CVPR #261 CVPR #261 CVPR 2016 Submission #261. CONFIDENTIAL REVIEW COPY. DO NOT DISTRIBUTE.
Geeta: Gold Standard Annotated Data, Analysis and its Application

Importance of gold standard data in the ﬁeld of NLP is well-established. In this paper we describe the development of one such gold standard for Sanskrit annotated at various levels of linguistic analysis. We describe how such a domain speciﬁc gold standard data, in addition to being useful for training and evaluation, is also useful for teaching. With the help of a suitable interface of anus¯araka we demonstrate its usability for a linguist, and also for a learner.
Plastein reaction and its applications in food proteins or bioactive peptides

The present paper reviews the chemical mechanism and its applications of plastein reaction in the research field of food proteins.Potential application of the plastein reaction to enhance the ACE inhibitory and antioxidant activities of bioactive peptides is also introduced and the related chemical mechanism is suggested as structural reconstruction of peptide molecules by the reaction.
A new self-acquired knowledge process for Monte Carlo Tree Search

Computer Go is one of the most challenging field in Artificial Intelligence Game. In this area the use of Monte Carlo Tree Search has emerged as a very attractive research direction, where recent advances have been achieved and permitted to significantly increase programs efficiency. These enhancements result from combining tree search used to identify best next moves, and a Monte Carlo process to estimate and gradually refine a position accuracy (estimation function). The more the estimation process is accurate, the better the Go program performs. In this paper, we propose a new approach to extract knowledge from the Go tree search which allows to increase the evaluation function accuracy (BHRF: Background History Reply Forest). The experiments results provided by this new approach are very promising.
Fitting in Versus Learning: A Challenge for Migrants Learning Languages Using Smartphones

There is great interest in the potential of smartphones to enable language learning during daily activities. However, this overlooks the paradox faced by migrant learners that while they have the educational goal of seeking to improve their language skills, they also have the cultural goal of fitting into the host society. Inappropriate use of smartphones as learning aids makes learners stand out as outsiders. Here, we investigate the use of smartphones by migrants for Mobile Assisted Language Learning (MALL) in their daily lives. We report on their participation in the trial of a system that coupled a custom smartphone app with location-based hardware triggers. This presented learning activities based on scenarios from everyday life that were prompted when approaching relevant locations around a UK town. Analysis of pre- and post- interviews indicates that social and cultural influences affect the location, timing and type of learning undertaken using the system. Participants preferred to learn in ways that were unobtrusive, and deferred engagement with content if social context inhibited use of the phone. For example, playing audio in public was seen as inappropriate. Although the app was designed with location-specific content, many participants chose to study elsewhere and at other times, in addition to accessing content from the phone at the time and place that the activity was triggered. We conclude that social context and wanting to belong are important influences for migrant learners, and emphasise the potential of MALL systems in encouraging engagement with physical and digital spaces and reflections about citizenship.
A Randomized Prospective Pilot Study

Received August 11, 1999; revised November 17, 2000; accepted January 11, 2001. From the Department of Psychiatry, Beth Israel Medical Center, and New York State Psychiatric Institute, New York. Address correspondence to Dr. Hellerstein, New York State Psychiatric Institute, Unit 101, 1051 Riverside Drive, New York, NY 10032. Copyright 2001 American Psychiatric Association Patients with dysthymia have been shown to respond to treatment with antidepressant medications, and to some degree to psychotherapy. Even patients successfully treated with medication often have residual symptoms and impaired psychosocial functioning. The authors describe a prospective randomized 36-week study of dysthymic patients, comparing continued treatment with antidepressant medication (fluoxetine) alone and medication with the addition of group therapy treatment. After an 8-week trial of fluoxetine, medication-responsive subjects were randomly assigned to receive either continued medication only or medication plus 16 sessions of manualized group psychotherapy. Results provide preliminary evidence that group therapy may provide additional benefit to medication-responding dysthymic patients, particularly in interpersonal and psychosocial functioning. (The Journal of Psychotherapy Practice and Research 2001; 10:93–103) D disorder is a prevalent and debilitating disorder (3% to 6% lifetime prevalence) that is associated with high medical and psychiatric comorbidity. Recent reviews have described the potential benefits of combined psychotherapy and psychopharmacology for chronic depression and the need for more research in this area.
Identification and in silico structural and functional analysis of a trypsin-like protease from shrimp Macrobrachium carcinus

Macrobrachium carcinus (Linnaeus, 1758) is a species of freshwater shrimp widely distributed from Florida southwards to southern Brazil, including southeast of Mexico. In the present work, we identified a putative trypsin-like protease cDNA fragment of 736 nucleotides from M. carcinus hepatopancreas tissue by the 3′RACE technique and compared the deduced amino acid sequence to other trypsin-related proteases to describe its structure and function relationship. The bioinformatics analyses showed that the deduced amino acid sequence likely corresponds to a trypsin-like protease closely related to brachyurins, which comprise a subset of serine proteases with collagenolytic activity found in crabs and other crustacea. The M. carcinus trypsin-like protease sequence showed a global sequence identity of 94% with an unpublished trypsin from Macrobrachium rosenbergii (GenBank accession no. AMQ98968), and only 57% with Penaeus vannamei trypsin (GenBank accession no. CAA60129). A detailed analysis of the amino acid sequence revealed specific differences with crustacean trypsins, such as the sequence motif at the beginning of the mature protein, activation mechanism of the corresponding zymogen, amino acid residues of the catalytic triad and residues responsible for substrate specificity.
Classification of large wildfires in South-Eastern France to adapt suppression strategies

Large wildfires keep on developing in the French Mediterranean region, regularly threatening responders. We tested if these large fires could be classified into types, and if these types were representative of different environmental drivers. To proceed, we established a database comprising 153 of the largest fires from the last 25 years. For each fire we collected three datasets to describe the environment, the fire behavior and the control operations. We performed a hierarchical clustering analysis followed by a predictive analysis with Bootstrap Regression Trees. Fires were classified in 8 types that could a posteriori be reduced to 5 types. The One-way type was featured by moderate environmental parameters, the Multi-way type was featured by slope, the Winding and Rapid types were featured by wind, while the Very large type was featured by the drought code. Moreover, the probability of having vehicles trapped in a large fire was primarily correlated with the number of vehicles assigned for suppression. This study provides the basis for upcoming trainings of Fire Analyst in France. It paves the way for further research on predictive wildfire danger mapping.
Dissecting the telomere-independent pathways underlying human cellular senescence

Cellular senescence is an irreversible program of cell cycle arrest triggered in normal somatic cells in response to a variety of intrinsic and extrinsic stimuli including telomere attrition, DNA damage, physiological stress and oncogene activation. Finding that inactivation of the pRB and p53 pathways by SV40-LT antigen cooperates with hTERT to immortalize cells has allowed us to use a thermolabile mutant of SV40-LT to develop human fibroblasts where the cells are immortal if grown at 34oC but undergo an irreversible growth arrest within 5 days at 38oC. When these cells cease dividing, senescence-associated-β-galactosidase (SA-β-Gal) activity is induced and the growth-arrested cells have many features of senescent cells. Since these cells growth-arrest in a synchronous manner, I have used Affymetrix expression profiling to identify the genes differentially expressed upon senescence. This identified 816 up- and 961 down-regulated genes whose expression was reversed when growth arrest was abrogated. I have shown that senescence was associated with activation of the NF-κB pathway and up-regulation of a number of senescence-associated-secretory-proteins including IL6. Perturbation of NF-κB signalling either by direct silencing of NF-κB subunits or by upstream modulation overcame growth-arrest indicating that activation of NF-κB signalling has a causal role in promoting senescence. I also applied a retroviral shRNA screen covering ~10,000 genes to the same cell model. Overlapping with the microarray data revealed particularly interesting targets, such as LTBP3 and Layilin. Finally, I profiled micro-rna expression. 15 of the top micro-rnas down-regulated upon senescence were chosen to express in the HMF3A system. 6 of them were able to bypass the growth-arrest. In conclusion, my work has uncovered novel markers involved in senescence as well as identifying that both activation of p53 and pRb pathway result in activation of NF-κB signalling which promotes senescence. Both results lead to a better understanding of senescence and its pathways.
Early signs of disrupted rule learning in adolescents at clinical high risk for psychosis

Background: The ability to flexibly apply rules to novel situations is a critical aspect of adaptive human behavior. Evidence from traditional neuropsychological tests suggest that broad executive function deficits appear early in the course of psychosis, but it is unclear which specific facets are affected. Identifying whether rule learning is impacted at the early stages of psychosis are necessary for truly understanding the etiology of psychosis and may be critical for designing novel treatments. Therefore, we examined rule learning in healthy adolescents and those meeting criteria for clinical high risk (CHR) for psychosis. Methods: 24 control and 22 CHR adolescents underwent rapid, high-resolution fMRI while performing a paradigm which required them to apply novel or practiced task rules. Results: Previous work with this task has suggested that practiced rules rely on rostrolateral prefrontal cortex (RLPFC) during task preparation and dorsolateral prefrontal cortex (DLPFC) during task performance, while novel rules showed the opposite pattern. In controls, we partially replicated this finding with a small effect of greater activity in RLPFC for practiced versus novel tasks; however, the CHR group showed a dysfunctional pattern of results. Not only did the CHR group show alternations in the expected brain dynamics, but they showed weaker effects than controls during both task preparation and task performance. Conclusions: These findings suggest that the critical ability to flexibly apply abstract rules is already disrupted at the clinical high risk stage of psychosis. However, more data is needed to determine whether these deficits predict disease progression. 2/49 without crediting the original authors. in the Public Domain. It is no longer restricted by copyright. Anyone can legally share, reuse, remix, or adapt this material for any purpose The copyright holder has placed this preprint (which was not peer-reviewed) . https://doi.org/10.1101/2020.01. 20.20018069 doi: medRxiv preprint
A first-principles study of nitrogene with monovacancy and light-atom substituted doping

Recent studies have shown that group V monolayer, called nitrogene, remain stable in a free-standing buckled honeycomb structure with a two-dimensional hexagonal lattice. It is predicted to be a nonmagnetic, wide band gap semiconductor. In this paper, three allotropes of nitrogen single layers are firstly investigated and it is determined that the buckled honeycomb structure of nitrogene (denoted as b-N) is the lowest energetically. Then taking b-N as an example, the geometrical structures and the electronic properties of it with monovacancy and substituted doping with heterogeneous atoms, such as B, C, O, Al, Si, and P, are studied. It is found that the single vacancy in b-N is in P3m symmetry and it is polarized stable with a local magnetic moment of 3.0 μB for each monovacancy. The substituted heterogeneous atom has little impact on the geometrical structures, while for Al, Si, and P, they move upward of the nitrogene plane due to the larger atomic radius compared to N. It is also found that C-, Si-, and O-doped nitrogene are spin-polarized stable, bringing a magnetic moment of about 1.0 μB for each doped atom. Doping of multiple carbon atoms in one hexagonal ring of nitrogene, which prefers forming the polymer and the nitrogene with the doping of an odd number of carbon atoms, is magnetic stable, arising about 1.0 μB magnetic moment in each supercell.
On the Importance of Metabolic Stability to Achieve High Oral Exposures for Cyclic Peptides

Following up on a previous publication in which we reported a high liver first pass effect in rats for the cyclic peptide (1) [Ala-Leu-NMe-D-Leu-NMe-Leu-Leu-D-Pro], we decided to investigate the type of metabolites formed and to suggest solutions to this problem. As a result of a bile duct cannulation study in rats and subsequent derivatization of this peptide by an isolated Cyp-enzyme, several hydroxylated variants were identified. Cyclopropyl-Ala (Cpa) residues as surrogates for Leu alleviated metabolism at these particular side chains. Significant progress was achieved, when in addition the D-Pro residue was exchanged by 4,4 difluoro-D-Pro (DiF-D-Pro). Albeit the Ala was kept constant in this process, in the corresponding in-vivo studies in rats, peptide (6) [Ala-Cpa-NMe-D-Cpa-NMe-Cpa-Cpa-4,4 difluro-D-Pro] exhibited mM exposures at 3mg/kg and an absolute oral bioavailability of > 90%. Thus, we emphasize the importance of controlling metabolism to achieve significant systemic exposure upon oral administration and suggest the Cpa- and DiF-D-Pro residues as metabolically stable isosteres for Leu, and D-Pro respectively.
Emulsifying properties of whey protein concentrate and caseinomacropeptide of cow, ewe and goat

The emulsifying activity index was shown to be significantly higher in the case of the whey protein concentrate (WPC) compared to caseinomacropeptides (CMP) (185 and 36 m 2 .g - 1 , respectively). The emulsifying activity index showed a dependent behaviour on pH and protein concentration for WMP and three CMPs. The emulsifying stability index of WMP changed significantly with pH and ionic strength. For CMPs from the 3 different species, the emulsifying stability did not show a significant variability with respect to pH but showed a dependence on ionic strength. The CMPs had a more stable emulsifying activity index with respect to pH than WMP, suggesting the possible utilisation of CMP as an emulsifier in foods which undergo large pH variations during processing (i.e. fermented dairy products).
Measuring the Impact of Culture on Critical Success Factors for Global Information System Implementations

The implementation of a global information system (IS) is a complex technological and social endeavor. This mixed methods research explored these difficulties through the holistic analysis of a global Product Lifecycle Management (PLM) IS implementation project conducted by an international business. The study filled a gap in the literature by identifying PLM Critical Success Factors (CSFs), and by providing a method to measure the impact of culture on PLM CSFs.
Rumen fermentation characteristics, ciliate protozoa and utilization of nutrients in sheep fed sodium hydroxide treated mustard straw

Mustard straw (MS) was treated with sodium hydroxide (2% w/v) by soaking (6 hr) method. Mulpurn rams (8) were divided into 2 groups. One grcup (G1) was offered untreated MS (UMS) ad lib. along with concentrate (1% common salt) @ 250 g /head/day, and group (G2) was offered (reated MS (TMS) ad lib. along with concentrate (without common salt) @ 250 g /head/day. Daily intakes of DM and OM between groups did not differ signiflcantly. However. rams in G2 consumed 12% higher amount of straw. The rumen pH increased and TVFA (meg/dl SRL) decreased in G2 as compared to G1. However, the concentration (mg/dl SRL) oftotal-N, Nll3-N and TCA-N was similar in G2 and G1. The population (X 104/ml SRL) of spirotrichs was lower in G 1 than that in G2 while of holotrichs higher in G1 than that in G2. Digestibility coefficients ofDM, OM, NDF, ADF and cellulose were higher in G2 than that in Gland the respective means were 45.8 and 52.9, 51.3 and 58, 38.1 and 47, 31.4 and 39.6 and 36.8 and 54.0. However, CP, hemicellulose and gross energy digestibility did not show much variation. Rams in both the groups were Oil positive N balance and N retention (% of N intake) was 37.7 and 47.1 in Gland 02 respectively. The DCP (%) of the ration was higher in Gl (7.0) than that in (12(5.6), whereas DE (Mcal/kg) of the ration did not differ significantly in G1 (2.4) and G2 (2.5). It is concluded that on feeding of sodium hydroxide treated mustard straw-based ration, the number of holotriehs protozoa decreascd while spirotrichs increased in the rumen of sheep. The soaking of mustard straw in 2% sodium hydroxide solution for 6 hr improved its palatability and digestibility and thus feeding value.
Population Growth Control Policy and Its Effect to Law Enforcement

In minimizing population growth that occurs in Indonesia one of them can be done with a family planning program (KB) that has been carried out by the government. In accordance with the framework and ideals of the Indonesian people listed in the opening of the 1945 Constitution. The purpose of the study was to describe the implementation of improving population control through family planning programs in Semarang District in terms of Article 4 Paragraph (1) of the Central Java Regional Regulation No. 6 of 2013 and Knowing the supporting and inhibiting factors in overcoming population control through family planning programs in Semarang Regency. This legal research method uses a qualitative approach with a type of sociolegal research. The results of the study were obtained that (1) The implementation of family planning programs in Semarang Regency was carried out well from the central level to the field. The Office of PP, PA, and KB carry out regulations related to family planning programs which are the vision of the Regent. By communicating, providing information and education to the community and providing socialization and coordination in the implementation of family planning. (2) The supporting factor is the regulation on the implementation of family planning; there is reliable medical personnel. As for the inhibiting factors, not all communities accept the existence of a family planning program; community culture that is still strongly attached to each individual community. The conclusion is that the success of family programs goes very well and cannot be separated from community participation. So that it can be seen from the number of babies born can be reduced from 14,127 in 2015 and 13,328 in 2016 which are spread from 19 districts in Semarang Regency.
Software tools for the lightning performance assessment

This chapter describes two of the most adopted software tools for the evaluation of the lightning performance of transmission and distribution lines, namely FLASH and LIOV-EMTP (Lightning Induced OverVoltage - ElectroMagnetic Transient Program), together with some application examples. The FLASH program has been developed by IEEE Working Groups. LIOV-EMTP is the result of the integration between the EMTP and the LIOV code, developed by Alma Mater Studiorum - University of Bologna (Italy), Ecole Polytechnique Federale de Lausanne - EPFL (Switzerland), with the support of University of Rome `La Sapienza' and of Centro Elettrotecnico Sperimentale Italiano `G. Motta' CESI S.p.A. (Italy).