Miracle-dz/UniFAR-FTUs huggingface dataset:
An Individual Welfare Maximation Algorithm for Electricity Markets

An algorithm that allows a market participant to maximize its individual welfare in electricity spot markets is presented. The use of the algorithm in determining market equilibrium points, called Nash equilibria, is demonstrated. The start of the algorithm is a spot market model that uses the optimal power flow (OPF), with a full representation of the transmission system and inclusion of consumer bidding. The algorithm utilizes price and dispatch sensitivities available from the Hessian matrix and gradient of the OPF to help determine an optimal change in an individual's bid. The algorithm is shown to be successful in determining local welfare maxima, and the prospects for scaling the algorithm up to realistically sized systems are very good. Nash equilibria are investigated assuming all participants attempt to maximize their individual welfare. This is done by iteratively solving the individual welfare maximization algorithm until all individuals stop modifying their bids.
Canine intraspinal meningiomas: imaging features, histopathologic classification, and long-term outcome in 34 dogs.

BACKGROUND Meningioma is the most common primary intraspinal nervous system tumor in dogs. Clinical findings, clinicopathologic data, and treatment of these tumors have been reported sporadically, but little information is available regarding cerebrospinal fluid (CSF) analysis, histologic tumor grade, or efficacy of radiation therapy as an adjunct to cytoreductive surgery. ANIMALS Dogs with histologically confirmed intraspinal meningiomas (n = 34). METHODS A retrospective study of dogs with intraspinal meningiomas between 1984 and 2006 was carried out. Signalment, historical information, physical examination, clinicopathologic data, radiation therapy protocols, surgery reports, and all available images were reviewed. All tumors were histologically classified and graded as defined by the international World Health Organization classification scheme for central nervous system tumors. RESULTS Intraspinal mengiomas in dogs are most common in the cervical spinal cord but can be found throughout the neuraxis. Location is correlated with histologic grade, with grade I tumors more likely to be in the cervical region than grade II tumors. Myelography generally shows an intradural extramedullary compressive lesion. On magnetic resonance imaging, the masses are strongly and uniformly contrast enhancing and a dural tail often is present. CSF analysis usually shows increased protein concentration with mild to moderate mixed pleocytosis. Surgical resection is an effective means of improving neurologic status, and adjunctive radiation therapy may lead to an improved outcome. CONCLUSIONS AND CLINICAL IMPORTANCE Biopsy is necessary for definitive diagnosis, but imaging and CSF analysis can suggest a diagnosis of meningioma. Treatment of meningiomas with surgery and radiation therapy can result in a fair to excellent prognosis.
Evolution of the neurochemical profiles in the G93A-SOD1 mouse model of amyotrophic lateral sclerosis

In vivo 1H magnetic resonance spectroscopy (1H-MRS) investigations of amyotrophic lateral sclerosis (ALS) mouse brain may provide neurochemical profiles and alterations in association with ALS disease progression. We aimed to longitudinally follow neurochemical evolutions of striatum, brainstem and motor cortex of mice transgenic for G93A mutant human superoxide dismutase type-1 (G93A-SOD1), an ALS model. Region-specific neurochemical alterations were detected in asymptomatic G93A-SOD1 mice, particularly in lactate (−19%) and glutamate (+8%) of brainstem, along with γ-amino-butyric acid (−30%), N-acetyl-aspartate (−5%) and ascorbate (+51%) of motor cortex. With disease progression towards the end-stage, increased numbers of metabolic changes of G93A-SOD1 mice were observed (e.g. glutamine levels increased in the brainstem (>+66%) and motor cortex (>+54%)). Through ALS disease progression, an overall increase of glutamine/glutamate in G93A-SOD1 mice was observed in the striatum (p < 0.01) and even more so in two motor neuron enriched regions, the brainstem and motor cortex (p < 0.0001). These 1H-MRS data underscore a pattern of neurochemical alterations that are specific to brain regions and to disease stages of the G93A-SOD1 mouse model. These neurochemical changes may contribute to early diagnosis and disease monitoring in ALS patients.
Using pure and mixed objects in the training of object-based image classifications

Training of object-based land cover classifications is often performed with objects generated via image segmentation. The objects are commonly assumed to be thematically pure or excluded from training if a mixture of classes is associated with them. However, excluding mixed objects has several consequences such as reducing the size of the training data sets. In this study, it is hypothesized that mixed objects may be used in the training stage of a classification to increase the accuracy with which land cover may be mapped from remotely sensed data, with outputs evaluated in relation to a conventional analysis using only pure objects in training. WorldView-2 data covering the University Park campus of the University of Nottingham were submitted to a series of segmentation analyses in which a range of under- to over-segmentation outputs were intentionally produced. Training objects representing four classes (bare soil, impervious surfaces, vegetation, and water) were selected from the segmentation outputs, resulting in training samples of varying size and proportion of mixed objects. A single-layer artificial neural network equivalent to multinomial logistic regression and able to use both pure and mixed training units was adopted as the classifier. A visual inspection of the results shows that using mixed training objects produced land cover maps of higher quality. Furthermore, the overall and class-specific accuracy of the classifications was systematically higher when mixed training was used (e.g. up to 48% in overall accuracy). The advantage of using mixed objects in training was beneficial even when the size of the mixed training samples was equivalent to that of the pure training samples.
The Effects of Environmental Stressors and the Pathogen Ranavirus on Survival and Health of Juvenile Freshwater Turtles

By exposing wildlife to pesticides and fertilizers, humans may be indirectly increasing host susceptibility to pathogens. In order to further our understanding of the interaction between the ranavirus and anthropogenic factors, their effects need to be studied using reptiles. Observation of the effects on reptilian immune function in the presence of herbicides is important to show how wildlife populations may be affected by pathogens in the mildly polluted watersheds of central Virginia. In this study, 200 juvenile Red Eared Slider Turtles (Trachemys scripta elegans) were used to investigate the response of aquatic reptiles to ranavirus and herbicide exposure. After an experimental group of 100 turtles was exposed to a ranavirus, the change in mass of the turtles was measured over a six week period under exposure to Roundup Pro®, ShoreKlear®, Atrazine, and tap water in groups of 40 turtles per treatment. The study suggested that survival of sliders was not affected by exposure to the ranavirus or the herbicides.
Word set probability boosting for improved spontaneous dialog recognition

Based on the observation that the unpredictable nature of conversational speech makes it almost impossible to reliably model sequential word constraints, the notion of word set error criteria is proposed for improved recognition of spontaneous dialogs. The single-pass adaptive boosting (AB) algorithm enables the language model weights to be tuned using the word set error criteria. In the two-pass version of the algorithm, the basic idea is to predict a set of words based on some a priori information, and perform a rescoring pass wherein the probabilities of the words in the predicted word set are amplified or boosted in some manner. An adaptive gradient descent procedure for tuning the word boosting factor is formulated, which enables the boost factors to be incrementally adjusted to maximize the accuracy of the speech recognition system outputs on held-out training data using the word set error criteria. Two novel models which predict the required word sets are presented: (i) utterance triggers, which capture within-utterance long-distance word interdependencies, and (ii) dialog triggers, which capture local temporal dialog-oriented word relations. The proposed trigger and adaptive boosting (TAB) algorithm, and the single-pass adaptive boosting (AB) algorithm are experimentally tested on a subset of the TRAINS-93 spontaneous dialogs and the TRAINS-95 semispontaneous corpus, and the results summarized.
A novel ATTR L32V mutation causes familial amyloid polyneuropathy in a Bolivian family

We report a new transthyretin (ATTR) gene c.272C>G mutation and variant protein, p.Leu32Val, in a kindred of Bolivian origin with a rapid progressive peripheral neuropathy and cardiomyopathy. Three individuals from a kindred with peripheral nerve and cardiac amyloidosis were examined. Analysis of the TTR gene was performed by Sanger direct sequencing. Neuropathologic examination was obtained on the index patient with mass spectrometry study of the ATTR deposition. Direct DNA sequence analysis of exons 2, 3, and 4 of the TTR gene demonstrated a c.272 C>G mutation in exon 2 (p.L32V). Sural nerve biopsy revealed massive amyloid deposition in the perineurium, endoneurium and vasa nervorum. Mass spectrometric analyses of ATTR immunoprecipitated from nerve biopsy showed the presence of both wild‐type and variant proteins. The observed mass results for the wild‐type and variant proteins were consistent with the predicted values calculated from the genetic analysis data. The ATTR L32V is associated with a severe course. This has implications for treatment of affected individuals and counseling of family members.
Genetic factors affecting drug disposition in Asian cancer patients

Introduction: In the era of genomic medicine, it is increasingly recognized that ethnogeographic differences in drug pharmacology exist between Asian and other populations. This is particularly pertinent to oncology, where drugs forming the backbone of chemotherapy often have narrow therapeutic windows and are frequently dosed close to maximally tolerable levels. Areas covered: At the population level, ancestry is important because historical–biogeographical confluences have shaped population genetics and pharmacoethnicity in the Asian race through allelic differentiation and interethnic differences in inheritance patterns of linkage disequilibrium. At the individual level, cis- and trans-acting germline polymorphisms and somatic mutations in genes encoding drug-metabolizing enzymes and transporters act in a multifactorial manner to determine drug disposition phenotype and clinical response in Asian cancer patients. A growing body of evidence also finds that complex genetic interactions and regulation, including a multiplicity of gene control mechanisms, are increasingly implicated in genotype–phenotype correlates than has hitherto been appreciated – potentially serving as the mechanistic links between hits in non-coding regions of genome-wide association studies and drug toxicity. Together, these genetic factors contribute to the clinical heterogeneity of drug disposition in Asian cancer patients. Expert opinion: This topic has broad relevance for the optimization and individualization of anticancer strategies in Asians.
Spectral Analysis for Delay Differential-Algebraic Systems

The aim of this paper is the study of the stability properties of a class of systems expressed by functional differential equations coupled with difference equations. Starting by the linear case, we extend the spectral projection methodology for Lossless systems by introducing an appropriate bilinear form. A sufficient criteria for convergence of series expansion for the considered system is established. For the nonlinear case, the center Manifold theorem is extended to functional differential equations coupled with difference equations leading to reducing the dimension of the initial system. Finally, we illustrate the obtained results by computational example.
Spectrum of PTCH mutations in Italian nevoid basal cell‐carcinoma syndrome patients: Identification of thirteen novel alleles

The nevoid basal cell carcinoma syndrome (NBCCS) is an autosomal dominant genetic disease characterized by numerous basal cell carcinomas, odontogenic keratocysts of the jaws, palmar and plantal pits, skeletal abnormalities, and calcification of the falx cerebri. The gene responsible for this syndrome is the PTCH tumor suppressor gene encoding for the sonic hedgehog receptor. In this paper, we report thirteen novel mutations identified in the first screening of NBCCS patients in Italy. Except for p.T230P and p.F505_L506delinsLR, all the other mutations are predicted to determine a premature truncation of the protein. © 2004 Wiley‐Liss, Inc.
Substitution of the Universal Motor drives with electrolytic capacitorless PMSM drives in home appliances

The Universal Motors (UM) have been used for a long time in variety of small and cheap drives, mainly in home appliances and hand tools. Their main features are cheapness, robustness and simplicity of the control, which make them still attractive. However during last twenty years they are replacing with drives of other types, mainly with induction and Permanent Magnet Synchronous Motor (PMSM) drives, which are more efficient and have better performance. This paper presents new generation of the motor drives for home appliances - electrolytic capacitorless PMSM drive, where electrolytic capacitor in the DC-link of the inverter is substituted with a small film one. The main purpose of them is to substitute UM, which are still used. Proposed drives have simple control system, decreased size, increased reliability and cost less than the conventional PMSM drives. Elimination of the electrolytic capacitor increases total device reliability, saves space, and improves spectrum of the input current, so Power Factor Corrector (PFC) used to satisfy existing standards on harmonic current emission can be omitted, which decreases size and cost of the appliances.
Light Field Rendering for Head Mounted Displays using Pixel Reprojection

Light field displays have advantages over traditional stereoscopic head mounted displays, for example, because they can overcome the vergence-accommodation conflict. However, rendering light fields can be a heavy task for computers due to the number of images that have to be rendered. Since much of the information of the different images is redundant, we use pixel reprojection from the corner cameras to compute the remaining images in the light field. We compare the reprojected images with directly rendered images in a user test. In most cases, the users were unable to distinguish the images. In extreme cases, the reprojection approach is not capable of creating the light field. We conclude that pixel reprojection is a feasible method for rendering light fields as far as quality of perspective and diffuse shading is concerned, but render time needs to be reduced to make the method practical.
A novel wideband circularly polarized microstrip antenna array for LTE MIMO terminal

A wideband circularly polarized (CP) microstrip multiple-input-multiple-output (MIMO) antenna for long term evolution (LTE) systems is proposed. Wideband feed network (WFN) based on coupled-line power divider and phase shifter is utilized to provide two ways of orthogonal signal. Then a square patch loaded with quad-symmetrical slots produces the CP radiation. The antenna design is simulated and the results of S-parameters are verified.
Hemisynthesis, Antitumoral Effect, and Molecular Docking Studies of Ferutinin and Its Analogues

The natural product ferutinin was shown to act as an agonist to estrogen receptor ERα and agonist/antagonist to ERβ featuring a weak antiproliferative activity toward breast cancer cells. To enhance this activity, ferutinin analogues were synthesized by esterification of jaeschkenadiol with different acids. These compounds were assayed for their in vitro antiproliferative activity against estrogen‐dependent (MCF‐7) and estrogen‐independent (MDA‐MB‐231) breast cancer cell lines. Among the compounds, 3c’ exhibited a potent inhibitory selective activity against MCF‐7 with IC50 value of 1 μm. Docking simulation of 3c’ in the ligand binding domain of the ERs indicated a potential antagonism interaction with both ER subtypes. Functional assay showed that 3c’ binds as an antagonist to ERα protein while ferutinin acts as an agonist.
Molecular cloning, expression profiles, and characterization of a novel polyphenol oxidase (PPO) gene in Hevea brasiliensis

The polyphenol oxidase (PPO) is involved in undesirable browning in many plant foods. Although the PPOs have been studied by several researchers, the isolation and expression profiles of PPO gene were not reported in rubber tree. In this study, a new PPO gene, HbPPO, was isolated from Hevea brasiliensis. The sequence alignment showed that HbPPO indicated high identities to plant PPOs and belonged to dicot branch. The cis-acting regulatory elements related to stress/hormone responses were predicted in the promoter region of HbPPO. Real-time RT-PCR analyses showed that HbPPO expression varied widely depending on different tissues and developmental stages of leaves. Besides being associated with tapping panel dryness, the HbPPO transcripts were regulated by ethrel, wounding, H2O2, and methyl jasmonate treatments. Moreover, the correlation between latex coagulation rate and PPO activity was further confirmed in this study. Our results lay the foundation for further analyzing the function of HbPPO in rubber tree. Graphical Abstract The WRKY71OS and transcription initiation site were highlighted with square frame and bold letter, respectively. The other cis-acting regulatory elements were underlined.
Results IL-12 Inhibits IgE , Eosinophil , and Intestinal

From the Departments of *Medicine, ~Pediatrics, and SMicrobiology and Immunology, Uniformed Services University of the Health Sciences, Bethesda, Maryland 20814; the IILaboratory of Parasitic Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland 20892; the 82 of Inflammation/ Autoimmune Diseases, Hoffmann-La Roche, Inc., Nutley, New Jersey 07110; "*Genetics Institute, Inc., Cambridge, Massachusetts 02140; and ~r Diseases Laboratory, Livestock and Poultry Sciences Institute, Agricultural Research Service, U.S. Department of Agriculture, Beltsville, Maryland 20705
Fear conditioning and brain activity: a positron emission tomography study in humans.

Regional cerebral blood flow (rCBF) was measured with H2 (15)O positron emission tomography in 8 healthy women before and after fear conditioning (i.e., paired shocks) and unpaired shocks to videotape cues. Conditioning was supported by enhanced peripheral nervous system recordings and subjective ratings. Fear conditioning increased rCBF in the central gray of the midbrain; bilaterally in the hypothalamus, the thalamus, and the left striatum; and in the right and left anterior cingulate and right prefrontal cortices. Regional CBF was attenuated bilaterally in the right and left prefrontal, temporal (including the amygdala), parietal, and occipital cortices, and in the left orbitofrontal cortex. When compared with unpaired shock presentations, fear conditioning resulted in elevated rCBF in the left cerebellum. Hence, in the present paradigm, only neural activity in the left cerebellum solely reflected processes associated with true Pavlovian conditioning.
MANY DROPLET PATTERN IN THE CYLINDRICAL PHASE OF DIBLOCK COPOLYMER MORPHOLOGY

The Ohta–Kawasaki density functional theory of diblock copolymers gives rise to a nonlocal free boundary problem. In a proper range of the block composition parameter and the nonlocal interaction parameter, an equilibrium pattern of many droplets exists in a general planar domain. A sub-range of the parameters is identified where the multiple droplet pattern is stable. This stable droplet pattern models the cylindrical phase in the diblock copolymer morphology. Each droplet is close to a round disc. The boundaries of the droplets satisfy an equation that involves the curvature of the boundaries and a quantity that depends nonlocally on the whole pattern. The locations of the droplets are determined via a Green's function of the domain. In constructing the droplet pattern we overcome three obstacles: interface oscillation, droplet coarsening, and droplet translation.
ON ROBUSTNESS PROPERTY OF DYNAMICAL SYSTEMS FEEDBACK CONNECTION WITH RESPECT TO MULTIPLICATIVE DISTURBANCES

Feedback connection of (strict) passive systems with multiplicative disturbance on the input of one of systems is considered. Series of conditions are proposed, which provide (strict) passivity property for overall system. These conditions enlarge result from Hill, and Moylan (1977), where passivity property of such connection was established. Applications of proposed results to backstepping control and adaptive output control are investigated. Copyright © 2004 IFAC
Robust Locally Weighted Regression for Superresolution Enhancement of Multi-Angle Remote Sensing Imagery

This paper presents a robust locally weighted least-squares kernel regression method for superresolution (SR) enhancement of multi-angle remote sensing imagery. The method is based on the concept of kernel-based regression, where the local image patch is approximated by an \mbiN-term Taylor series. To reduce the impact of high frequency noise on SR performance, a robust fitting procedure is adopted. The approach proposed is tested with simulated multi-angle data derived from panchromatic WorldView-2 imagery and with real multi-angle WorldView-2 remote sensing images.
Low-Cost Superimposed Pilots Based Receiver for Massive MIMO in Multicarrier System

In this paper, we present a low-cost receive algorithm for massive Multiple-Input Multiple-Output (MIMO) system, which exploits 2-dimensional superimposed pilots in time and frequency domain. By introducing the well designed superimposed pilots, the pilot contamination can be systematically suppressed. Even within a small time-frequency allocation, transforming the 2-dimensional superimposed pilots to an equivalent one-dimensional orthogonal pattern, the provided processing gain can be adequate to achieve precise channel estimation on the basis of linear operations. In this paper, we provide the proof-of-concept with link layer simulation for multicarrier system. Additionally, the 2-dimensional trellis-based channel estimation, as a high-cost solution, will be compared to the proposed solution, in order to quantify the reasonability of the trade-off.