Miracle-dz/UniFAR-FTUs huggingface dataset:
School of Economics and Finance Financial Regimes and Uncertainty Shocks

Financial markets are central to the transmission of uncertainty shocks. This paper documents a new aspect of the interaction between the two by showing that uncertainty shocks have radically different macroeconomic implications depending on the state financial markets are in when they occur. Using monthly US data, we estimate a nonlinear VAR where economic uncertainty is proxied by the (unobserved) volatility of the structural shocks, and a regime change occurs whenever credit conditions cross a critical threshold. An exogenous increase in uncertainty has recessionary effects in both good and bad credit regimes, but its impact on output is estimated to be five times larger when the economy is experiencing financial distress. Accounting for this nonlinearity, uncertainty accounts for about 1% of the peak fall in industrial production observed in the 2007—2009 recession.
Ziprasidone Induction of Hypomania in Depression ?

Ms. A, a 36-year-old woman, had pronounced repetitive self-mutilating behavior in addition to borderline personality disorder diagnosed according to an interview with the German version of the Dissociative Disorders Interview Schedule (1) (DSM-IV diagnoses 296.32, 300.6, 300.12, 300.15, 300.81, 301.83, and 307.1). She collected her entire nocturnal (8:00 p.m. to 8:00 a.m.) urine output on 86 consecutive nights (2) Her nocturnal urinary volumes were almost identical (mean=983 ml, SD=128), but the fluctuations in her nocturnal cortisol excretion were extreme, varying from 2 to 30 μg a night. Compared to normative data (cortisol excretion during 24 hours: 20–90 μg/day), her nocturnal cortisol secretion appears low on average; this is in accordance with data from other studies (3). However, our longitudinal study revealed that periods of low cortisol excretion were followed by periods of continuous increases in excretion over several nights. Above 20 μg a night, she performed one or several acts of selfmutilation. Subsequently, an instantaneous decrease to low initial baseline values of cortisol was observed. Thereafter, her nocturnal cortisol excretion remained at this low level for several days. The next period of increasing cortisol secretion was again terminated by an episode of selfmutilation.
Development and characterization of a carvedilol-loaded self-microemulsifying delivery system

The objective of the work was to develop, optimize, and evaluate a self-microemulsifying drug delivery system of the poorly water-soluble drug, carvedilol. Solubility of carvedilol was determined in various vehicles. Ternary and pseudo-ternary phase diagrams were constructed to indentify the efficient self-emulsification region using oils, surfactants, and co-surfactants in aqueous environment. Optimized formulations were assessed for drug content, spectroscopic clarity, emulsification time, contact angle, zeta potential, particle size, and dissolution studies. Zeta potential was measured in the absence and presence of oleylamine, a positive charge inducer. On the basis of similarity and dissimilarity of particle size distribution, formulations were characterized using PCA and AHCA, a multivariate statistical analysis. Decrease in t50% and increase in DE attributed to small globule size and eventually higher surface area. The relevance of differences in t50% and DE was evaluated statistically by two-way ANOVA. DRIFTS, DSC, and X-RD studies indicated no incompatibility between drug, oil, and surfactants. The results of this study indicate that the SMEDD formulations of carvedilol owing to nanosize have the potential to enhance its absorption, without interaction or incompatibility between the ingredients.
CEP Discussion Paper No 1469 February 2017 Multi-Product Firms and Product Quality Kalina Manova

We examine the global operations of multi-product firms. We present a flexible heterogeneous-firm trade model with either limited or strong scope for quality differentiation. Using customs data for China during 2002-2006, we empirically establish that firms allocate activity across products in line with a product hierarchy based on quality. Firms vary output quality across their products by using inputs of different quality levels. Their core competence is in varieties of superior quality that command higher prices but nevertheless generate higher sales. In markets where they offer fewer products, firms concentrate on their core varieties by dropping low-quality peripheral goods on the extensive margin and by shifting sales towards top-quality products on the intensive margin. The product quality ladder also governs firms' export dynamics, both in general and in response to the exogenous removal of MFA quotas on textiles and apparel. Our results inform the drivers and measurement of firm performance, the effects of trade reforms, and the design of development policies.
ACUTE EFFECTS OF DYNAMIC STRETCHING ON VERTICAL JUMP: A SYSTEMATIC REVIEW AND META-ANALYSIS

The aim of the study was to determine the quantity of dynamic stretching exercises for the lower limbs that cause better vertical jump. This study followed the systematic review methodology that was proposed in PRISMA statement. The studies were identified in electronic databases during October of 2013 to February of 2014. Literature searches were conducted in Google Scholar, Research Gate, PubMed, Medline, Scielo, Dialnet and in CAPES journals. The studies that were included in this systematic review and metaanalysis had a total of 14 studies. The effect size of 1 to 5 dynamic stretching exercises was of 13,19±28 (great effect) and the effect size of 6 to more dynamic stretching exercises was of 0,48±0,4 (small effect). Shapiro Wilk test determined that the data are not normal and the histogram showed the data not normal. Mann-Whitney U test detected no significant difference (U = 15, p = 0,52) between 1 to 5 dynamic stretching exercises versus 6 to more dynamic stretching exercises. However, 1 to 5 dynamic stretching exercises had better countermovement jump. In conclusion, it seems that 1 to 5 dynamic stretching exercises cause a better countermovement jump, however, more studies on this theme are needed with the objective of corroborate this affirmation.
Simulation Aids Long-Term Capacity Planning at a Sunglasses Manufacturing Plant

Discrete-event process simulation has long been able to analyze knotty problems arising in manufacturing, warehousing, health care, transportation (rail, air, bus, etc.), and service industries such as banks, restaurants, and hotels. These knotty problems include challenges such as reducing inventory, increasing production (throughput), deploying workers efficiently, and reducing both lengths of queues and time spent in those queues. Indeed, from a historical perspective, the first, and still some of the most conspicuous, successes of simulation have been achieved in its applications to manufacturing. The application of simulation described in this paper arose in the context of manufacturing safes from their raw-material shells. Simulation, in contrast to other methods such as closed-form optimization, is highly capable of accommodating high process variability and almost automatically providing “best-case” and “worst-case” (as well as averages) for important performance metrics such as lengths of queues and waiting times in queues. Additionally, the animation which routinely accompanies simulation helps non-technical managers understand the results. In this context, the most painfully pressing problem was excess inventory, coupled with too slow and too meager output. The simulation study guided engineers and managers as they endeavored to both reduce the inventory and increase the rate of output – only very rarely can these two objectives be achieved concurrently. Keywords-discrete-event process simulation, manufacturing, capacity planning, throughput, queuing analysis, inventory
Multivariate Realised Kernels: Consistent Positive Semi-Definite Estimators of the Covariation of Equity Prices with Noise and Non-Synchronous Trading

We propose a multivariate realised kernel to estimate the ex -post covariation of log-prices. We show this new consistent estimator is guaranteed to be posit ive emi-definite and is robust to measurement noise of certain types and can also handle non-sync hronous trading. It is the first estimator which has these three properties which are all essential for empirical work in this area. We derive the large sample asymptotics of this estimator and assess it accuracy using a Monte Carlo study. We implement the estimator on some US equity data, comparing ou r res lts to previous work which has used returns measured over 5 or 10 minutes intervals. We show the new estimator is substantially more precise.
Biospeci c Immobilization of Lactoperoxidase on Con A-Sepharose 4 B

The aim of this work was to evaluate the possibilities of immobilization of lactoperoxidase (LPO) on concanavalin A-Sepharose 4B support. Signi cant biospeci c interaction of this heme-containing glycoenzyme with Con A was established by using -D-mannopyranoside and -D-glucopyranoside, which are involved in the linking of the carbohydrate moieties of the enzyme with lectin. The preparation obtained indicated improved kinetic parameters (Km and Vmax) compared with the soluble form. No signi cant di erences were observed between the optimal pH and temperature of the anchored and free enzymes. The thermal stability of the biospeci cally immobilized preparation was substantially higher than that of the unbound enzyme. In addition, seven cycles of enzymatic conversion and washing of the column showed the remarkable operational stability of immobilized LPO.
Assessment of Opioid Misuse 1 RUNNING HEAD: ASSESSMENT OF OPIOID MISUSE IN CHRONIC PAIN DEVELOPMENT OF A SELF-REPORT SCREENING INSTRUMENT FOR ASSESSING POTENTIAL OPIOID MEDICATION MISUSE IN CHRONIC PAIN PATIENTS*

This study comprised the first step in the psychometric development of a self-report screening instrument for risk of opioid medication misuse among chronic pain patients. A 26item instrument, the Pain Medication Questionnaire (PMQ), was constructed based on suspected behavioral correlates of opioid medication misuse, which heretofore have received limited empirical investigation. The PMQ was administered to 184 patients at an interdisciplinary pain treatment center. Reliability coefficients for the PMQ were found to be of moderate but acceptable strength. Construct and concurrent validity were examined through correlation of PMQ scores to measures of substance abuse, physical and psychological functioning, and physicians’ risk assessments. To explore high and low cutoff points for misuse risk, subgroups were formed according to the upper and lower thirds of PMQ scores and compared on validity measures. Higher PMQ scores were associated with history of substance abuse, higher levels of psychosocial distress, and poorer functioning. Future psychometric analyses will consider predictive validity and examine shortened versions of the instrument.
evelopment of 2 . 4-GHz film bulk acoustic wave lter for wireless communication

ei-Zen Chang ational Taiwan University nstitute of Applied Mechanics , Sec. 4, Roosevelt Road aipei 106, Taiwan Abstract. This research shows the realization of 2.4-GHz film bulk acoustic wave FBAW filters. The design, simulation, fabrication, measurement, and analysis of the film bulk acoustic wave resonator FBAR devices are covered, which is helpful for the manufacture of the FBAR devices. The simulation of the FBAR and RF circuitry can be integrated on a single platform. The fabrication of the FBAW filters is compatible with complementary metal-oxide semiconductors. This device can be used in 2.4-GHz bandpass filters, such as 802.11b/g and Bluetooth. In this research, the 2.4-GHz FBAW filters for wireless communication have been accomplished. The fabricated FBAW filters have insertion loss of −10 dB, return loss of −7 dB, and stopband rejection of −25 dB, central frequency of 2.485 GHz, bandwidth of 60 MHz, and size of 0.5 mm 0.5 mm. © 2009 Society of Photo-Optical Instrumentation Engineers. DOI: 10.1117/1.3094749
Confrontation with stress in women with disturbed eating habits

INTRODUCTION. The aim of the present study was to assess coping strategies among women with disturbed eating habits. The following questions were asked: 1) Are there any differences between women suffering from anorexia, bulimia and obesity and healthy population with respect to cope with stress? 2) Which of coping strategies determine disturbed eating habits? MATERIAL AND METHODS. The Brief COPE by Carver (1997) was applied to 121 women with disturbed eating habits (anorexia, bulimia, obesity) and 83 healthy women. RESULTS. Women with bulimia nervosa manifest more maladaptive (emotion-focused coping) coping strategies than women with anorexia. However, women with eating disorders use more problem-focused coping than those without disturbed eating habits. CONCLUSIONS. In the absence of suitable coping strategies among persons with eating disorders it’s necessary to work out effective stress reduction methods.
Potential use of two subtropical mangrove species (Laguncularia racemosa and Rhizophora mangle) for nutrient removal in closed recirculating systems

Six silvofishery systems were constructed to estimate the potential use of mangrove seedlings for nutrient removal. Two systems did not contain seedlings (i.e., control treatment), while the remaining systems were divided into separate treatments using two mangrove species (Laguncularia racemosa and Rhizophora mangle). Each system consisted of two water tanks linked by two hoses. The first tank contained 150 poeciliid fishes, while the second contained a biological filter of gravel and sand on the bottom, as well as a hydroponic arrangement of 34 seedlings. Water exchange between both tanks was performed over a 24-h period, every ten days for seven months, and the concentration of nutrients (NH4 +, NO2 –, NO3 –, and PO4 –3) was measured every 8 h. Laguncularia racemosa showed a higher growth rate compared to R. mangle, but there were no differences regarding the growth of fishes among the six systems. Final dissolved inorganic nitrogen removal was 42% in the control treatment and 90% in both treatments using mangroves. Dissolved inorganic phosphorus removal was 45% in the control treatment, 44% in the L. racemosa treatment, and 35% in the R. mangle treatment. Our results indicate that both mangrove species are capable of removing a considerable amount of nitrogen, but phosphorus removal was unsatisfactory. Seis sistemas de cultivo fueron construidos para evaluar el uso potencial de plantulas de mangle en la remocion de nutrientes. Dos de los sistemas no contenian plantulas (i.e., control), mientras que los sistemas restantes fueron divididos en tratamientos por separado con dos especies de mangle (Laguncularia racemosa y Rhizophora mangle). Cada sistema consistio en dos tanques de almacenamiento unidos por dos tubos. El primer tanque contenia 150 peces poecilidos, mientras que el segundo tanque contenia 34 plantulas en forma hidroponica y un filtro biologico de grava y arena en el fondo. Se hicieron recirculaciones de agua entre ambos tanques cada diez dias por un periodo de siete meses. Durante cada recirculacion, se midio la concentracion de nutrientes (NH4 +, NO2 –, NO3 – y PO4 –3) cada 8 h. Laguncularia racemosa presento una tasa de crecimiento mayor comparada con R. mangle; sin embargo, el crecimiento de los peces fue igual entre los seis sistemas. El porcentaje final de nitrogeno inorganico disuelto fue 42% en el tratamiento de control y 90% en los tratamientos con L. racemosa y R. mangle. El porcentaje de remocion de fosforo inorganico disuelto fue 45% en el control, 44% en el tratamiento con L. racemosa y 35% en el tratamiento con R. mangle. Los resultados indican que ambas especies de mangle son capaces de remover una cantidad considerable de nitrogeno, pero la remocion de fosforo fue insatisfactoria.
Mesmin Destin Identity-Based Motivation : Implications for Intervention

Children want to succeed academically and attend college but their actual attainment often lags behind; some groups (e.g., boys, low-income children) are particularly likely to experience this gap. Social structural factors matter, influencing this gap in part by affecting children’s perceptions of what is possible for them and people like them in the future. Interventions that focus on this macro–micro interface can boost children’s attainment. We articulate the processes underlying these effects using an integrative culturally sensitive framework entitled identity-based motivation (IBM). The IBM model assumes that identities are dynamically constructed in context. People interpret situations and difficulties in ways that are congruent with currently active identities and prefer identity-congruent to identity-incongruent actions. When action feels identity congruent, experienced difficulty highlights that the behavior is important and meaningful. When action feels identity incongruent, the same difficulty suggests that the behavior is pointless and “not for people like me. ”
An induction programme for first-appointment overseas doctors

The NHS provides training posts for many overseas doctors but job induction programmes usually assume the participants are UK graduates. The 'Orange Book' guidelines on Visiting Specialist Registrar training make job induction an important component of entry to the grade. This paper describes the constituents and outcomes of a pilot programme for overseas doctors starting their first appointment in the UK. This experience may prove useful to other countries that recruit foreign medical graduates.
An ultrastructural study of macrovascular changes in rats with diabetes mellitus and hypertension

Numerous investigators have presented evidence of increased mortality in patients with diabetes mellitus due to cardiovascular disease. The reasons for a predisposition to vascular pathology that, in the advanced state, can lead to atherosclerosis are still unclear. Our hypotheses were: 1) the condition of diabetes mellitus in a streptozocin animal model may show vascular changes similar to early pathology in macrovessels, 2) since the model is normotensive, inducing hypertension will result in early atherogenic pathology, 3) the response to diabetic and/or hypertensive circumstances may be diversified due to the function of blood vessels, and 4) endothelium is the initiator of vascular pathology in diabetes. To test these hypotheses, we carried out a quantitative analysis of the renal and coronary arteries from rats using light, transmission and scanning electron microscopy. Diabetes mellitus was induced with streptozocin and hypertension was induced using deoxycorticosterone acetate. There were four experimental groups: control, control/hypertensive, diabetic, and diabetic/hypertensive. In the renal artery, the tunica media and luminal areas significantly increased in the hypertensive groups, but proportionately, the vessel dimensions did not alter, with all four groups having similar tunica media/lumen ratios. There was a significant elevation of extracellular matrix surrounding
Obs . 6 : General considerations : The use of the terms " inverse / direct behavior " and " inverse / direct relationship "

Due to recent atmospheric and oceanic warming, The the Antarctic Peninsula is one of the most challenging regions of Antarctica to understand both localand regional-scale climate signals from a climatological perspective, owing to the recent atmospheric and oceanic warming. The sSteep topography and a lack of long–term and in situ meteorological 20 observations complicate the extrapolation of existing climate models to the sub-regional scale. Therefore, new techniques must be developed to better understand processes operating in the region. For example, iIsotope signals are traditionally related mainly to atmospheric conditions, however,but a detailed analysis of individual components can give new insight into oceanic and atmospheric processes. This paper aims to use new isotopic records collected from snow and firn cores in conjunction with existing meteorological and oceanic datasets to determine changes at the climatic scale in the northern 25 extent of the Antarctic Peninsula. In particular, Here, we present new evidence from the northern Antarctic Peninsula to demonstrate how stable water isotopes of firn cores and recent precipitation samples can reveal climatic processes related to nearby oceanic and atmospheric conditions. Aa noticeable discernablediscernible aeffecteffect of the sea ice cover on local temperatures and the expression 30 of atmospheric climatic modes, in particularespecially the Southern Annular Mode (SAM), is demonstrated. In years with a large sea ice extension in winter (negative SAM anomaly), an inversion layer in the lower troposphere develops at the coastal zone. Therefore, an isotope–temperature relationship (–T) valid for all seasons periods cannot be concludedobtained, and instead,. The the –T. relationship rather depends on the seasonal variability of oceanic conditions. 35 Comparatively, Transitional transitional seasons (autumn and spring) are both stable seasons with anhave a consistent isotope–temperature gradient of +0.69‰ °C. The As shown by firn core analysis, firn stable isotope composition reveals that the near–surface temperature at in the most northern-most portion of the Antarctic Peninsula shows a decreasing trend (0.33°C y) between 2008 and 2014. MoreoverIn addition, the deuterium excess (dexcess) has beenis demonstrated to be a reliable indicator of seasonal oceanic conditions, and therefore suitable to improve a firn age model based on seasonal dexcess 40 variability. The annual accumulation rate in this region is highly variable, ranging between 1060 kg m y and 2470 kg m y from 2008 to 2014. The combination of isotopic and meteorological data in areas where data exist is a key for to
TIME SERIES BASED HOURLY TRAFFIC FLOW PREDICTION ON THE GTA FREEWAYS USING TS-TVEC MODEL

Short term traffic flow prediction is a cornerstone for intelligent traffic operations, management, policy making, and strategy formulation. It is an essential instrument to support ATMS (advanced traffic management system) implementation and ATIS (advanced traveller information system) service such as congestion mitigation, ramp metering, road pricing, and route guidance, etc. among others. Traffic flow prediction is to forecast macroscopic traffic quantities including traffic volume, speed, and occupancy (i.e. analogy to density) three major indicators of traffic state for a short time future horizon. This research focuses on hourly traffic flow prediction based on advanced time series techniques.