Miracle-dz/UniFAR-FTUs huggingface dataset:
The impacts of iron limitation and ocean acidification on the cellular stoichiometry, photophysiology, and transcriptome of Phaeocystis antarctica

Phaeocystis antarctica is an integral player of the phytoplankton community of the Southern Ocean (SO), the world's largest high‐nutrient low‐chlorophyll region, and faces chronic iron (Fe) limitation. As the SO is responsible for 40% of anthropogenic CO2 uptake, P. antarctica must also deal with ocean acidification (OA). However, mechanistic studies investigating the effects of Fe limitation and OA on trace metal (TM) stoichiometry, transcriptomic, and photophysiological responses of this species, as well as on the Fe chemistry, are lacking. This study reveals that P. antarctica responded strongly to Fe limitation by reducing its growth rate and particulate organic carbon (POC) production. Cellular concentrations of all TMs, not just Fe, were greatly reduced, suggesting that Fe limitation may drive cells into secondary limitation by another TM. P. antarctica was able to adjust its photophysiology in response to Fe limitation, resulting in similar absolute electron transport rates across PSII. Even though OA‐stimulated growth in Fe‐limited and ‐replete treatments, the slight reduction in cellular POC resulted in no net effect on POC production. In addition, relatively few genes were differentially expressed due to OA. Finally, this study demonstrates that, under our culture conditions, OA did not affect inorganic Fe or humic‐acid‐like substances in seawater but triggered the production of humic‐acid‐like substances by P. antarctica. This species is well adapted to OA under all Fe conditions, giving it a competitive advantage over more sensitive species in a future ocean.
Apatinib for treatment of HGF in advanced lung adenocarcinoma harboring EGFR activating mutation : a case report and review of literature

Hepatocyte growth factor (HGF) is a complex, multi-domain protein related to the blood proteinase precursor plasminogen, known to be detected in 29% of tumors with intrinsic resistance in EGFR mutant lung cancer. However, the proportion of HGF in primary resistance of lung adenocarcinoma is not clear. We describe the case of a 54-year-old non-smoking man who was diagnosed lung adenocarcinoma via pathology test. The lymph nodes of his right neck, submandibular, left axillary, and mediastinal were metastasized. Next generation sequencing of the patient showed L858R in 21 exon and overexpression of HGF. Apatinib is a salvage treatment for patients after failure in response to chemotherapy and icotinib. Therefore, apatinib might be an optional choice for advanced lung adenocarinoma patients with HGF overexpression as a post second-line treatment.
Optimization of Production Cost of Film and Its Solution Method

Considering the difference between actors' fee, this paper constructed the model of movie talent scheduling problem to minimize the total costs of talents. According to the characteristic of the problem, this paper applies the genetic algorithm with elitist strategy and the discrete particle swarm optimization algorithm which combined genetic operations and can adjust the inertia weight dynamically to work out this problem in different sizes. Experimental results show that, the genetic algorithm with elitist strategy can obtain a better solution when the problem size is small, while the discrete particle swarm optimization is more efficient for the large scale problems.
The Effect of Transformational Leadership on Team Satisfaction: The Mediating Effect of Psychological Safety

Following hitherto published research on the positive outcomes of transformational leadership; I hypothesize that transformational leadership leads to higher team satisfaction. However, as suggested by Bass (1999), the mechanisms underlying the relationships between transformational leadership and the outcomes are still worthy of further examination. Thus, in this research, I tested psychological safety as mediating variables on the relationship between team perceptions of supervisors' transformational leadership and team satisfaction in the team level analysis. Based on the data from 83 teams mainly working on companies, the research shows that team perceptions of supervisors' transformational leadership is positively related to team satisfaction. In addition, psychological safety mediates the relationship between transformational leadership and team satisfaction. Finally, the implication for future research and managerial are discussed. Keywords— Transformational Leadership; Psychological Safety; Team Satisfaction
An Analysis of Topographic InSAR Algorithms

Interferometric synthetic aperture radar (InSAR) is a method which provides a means of estimating global topography with high spatial resolution and height accuracy. The general formulation, giving relationship between the interferogram phase and the target height, is based on the interferometric SAR geometry and on a better expansion of the path length difference between the sensor and the target. To derive an estimate of the surface height, this technique uses the relative phase difference between two coherent SAR images obtained by two receivers separated by a cross-track baseline. Three measurements are required to reconstruct the three-dimensional coordinate of a point in an InSAR image: the range, azimuth, and elevation. In this paper, we focus on the study of topography reconstruction based on the orthogonal decomposition of the look vector of radar. We present an analytical analysis of Madsen geolocation algorithm in which the coordinates of the geolocated point are given in a geocentric Cartesian reference system.
On Intelligent Use of ICT in Some Maritime Business Organizations

The paper examines to what extent some maritime business organizations use intelligently available Information and Communication Technology (ICT) solutions, and in which manners the existing gap between ICT potentials and their real use on daily basis can be mitigated. As a focus group are identified ten maritime business entities from Albania, Croatia, Italy, Montenegro and Slovenia, which share the common Adriatic Sea market.
The role of user satisfaction in implementing a Business Intelligence System

Background: Despite increasing importance of the use of Business Intelligence (BI) as a technology-driven process for giving decision support, the success or failure of BI has not been investigated fully in South Africa. BI is not well understood because of an absence of documented proof of its practice. Objectives: This study was intended to investigate BI and identify the moderating and mediating effects of user satisfaction on the relationship between system quality, information quality and service quality on the one hand and perceived net benefits on the other in South Africa. Methods: The quantitative methods approach was predominantly used in this study. A total of 211 responses were obtained from a random sample of 250 BI users throughout South Africa. A semi-structured online survey questionnaire was used to collect the data, and correlation and multiple regression analyses were used to analyse it. Results: It was found that user satisfaction mediates the relationship between perceived net benefits and system quality and service quality. It also moderates the effects of system quality and service quality on perceived net benefits. Information quality is not related with user satisfaction and perceived net benefits. Conclusion: The implication of the results is that system quality and user satisfaction should be enhanced and maintained to achieve perceived positive net benefits in order to make the BI system more effective and efficient.
Co 3 O 4 nanoplates : Synthesis , characterization and study of optical and magnetic properties

The selective synthesis of spinel-type Co3O4 nanostructure with nanoplates morphology was successfully achieved by solid-state thermal decomposition of the [Co(NH3)6](C2O4) 4H2O complex at 350 C without employing any solvent, surfactant and complicated equipment. The product was characterized by thermal analysis (TG/DTA), X-ray diffraction (XRD), Fourier transform infrared spectroscopy (FT-IR), Raman spectroscopy, UV–visible spectroscopy, transmission electron microscopy (TEM), scanning electron microscopy (SEM), energy-dispersive X-ray spectroscopy (EDX) and magnetic measurements. The TEM images show that the product has a plate-like shape with length of 50–200 nm and thickness of 10– 20 nm. FT-IR, XRD, EDX and VSM results suggest the as-prepared Co3O4 nanoplates are pure and single-phase with a weak ferromagnetic behavior. The optical spectrum indicated two direct band gaps at 2.18 and 3.55 eV with a blue shift compared with the bulk samples. The plausible pathway for the formation of Co3O4 nanoplates was also proposed. Under the present reaction conditions, the decomposition of other cobaltammine complexes and CoC2O4 2H2O led to the Co3O4 nanoparticles and nanorods, respectively. 2013 Elsevier B.V. All rights reserved.
Community Origins of Industrial Entrepreneurship in Pre-Independence India

We argue that community networks played an important role in the emergence of Indian entrepreneurship in the early stages of the cotton textile and jute industry in the late 19th and early 20th century respectively, overcoming the lack of market institutions and government support. From business registers, we construct a yearly panel dataset of entrepreneurs in these two industries. We find no evidence of entry patterns being affected by price shocks or pre-industrial accumulation of wealth or experience in trading in the corresponding upstream sector. Firm directors exhibited a high degree of clustering of entrepreneurs by community. The dynamics of entry is consistent with a model of network-based dynamics.
BAYESIAN STATISTICAL PARAMETRIC VERIFICATION AND SYNTHESIS BY MACHINE LEARNING

We consider the problem of parametric verification, presenting a recent statistical method to perform parametric verification of linear time properties of stochastic models, estimating the satisfaction probability as a function of model or property parameters. The approach leverages Bayesian Machine Learning based on Gaussian Processes. Under mild conditions on continuity of parameters of the satisfaction probability, it can be shown that property satisfaction is a smooth function of such parameters. Gaussian Processes can effectively capture this smoothness and obtain more-accurate estimates of satisfaction probabilities by transferring information across the parameter space. We leveraged this approach to efficiently solve several tasks, like parameter synthesis, system design, counterexample generation, and requirement synthesis. In this tutorial, we will introduce the basic ideas of the approach and give an overview of the different applications.
An Independently Tunable Dual-Band Filter Using Asymmetric λ/4 Resonator Pairs with Shared via-Hole Ground

This paper presents a dual-band tunable bandpass fllter with independently controllable dual passbands based on a novel asymmetric ‚=4 resonator pair with shared via-hole ground. Because two separated passbands can be independently generated by the two ‚=4 resonators with difierent electric lengths, the asymmetric ‚=4 resonator pair can realize ∞exible passband allocation when it is utilized to design dual-band fllters. Two varactors are placed at the two open circuit ends of the asymmetric ‚=4 resonator pair to control the two dominant resonant frequencies, respectively. A prototype tunable dual-band fllter with Chebyshev response is designed and fabricated. The measured results are in good agreement with the full-wave simulated ones. The results show that the flrst passband varies in a frequency range from 0.88GHz to 1.12GHz with the 3-dB fractional bandwidth of 5.1%{6.4%, while the second passband can be tuned from 1.5GHz to 1.81GHz with the 3-dB fractional bandwidth of 5.4%{6.4%.
Mode-locking in an optical microresonator via soliton formation

The discovery of passive mode-locking of lasers via saturable absorbers[1] has led to optical femto-second pulses with applications ranging from eye surgery to the analysis of chemical reactions on ultra-short timescales[2, 3]. In the optical frequency domain a train of such pulses corresponds to a frequency comb (equidistant optical laser lines spaced by the pulse repetition rate)[4, 5], which find use in precision spectroscopy and optical frequency metrology[6, 7]. In an alternative approach, not relying on modelocking, frequency combs can also be generated in continuously driven, Kerr-nonlinear optical microresonators via cascaded parametric four-wave mixing[8–14]. Applying a pulse-shaping mode-locking mechanism could enable compact and robust femtosecond pulse generators. However, saturable absorbers are challenging to apply to microresonators as they affect the high quality factor essential to nonlinear frequency conversion. Here, we demonstrate passive mode-locking in microresonators via soliton formation. In contrast to soliton mode-locked lasers [15] a stabilizing saturable absorber is not required due to the parametric gain mechanism. We observe the generation of pulses with 200 fs duration and low noise frequency comb spectra with low line-to-line power variation. Numerical modeling of the nonlinear coupled mode equations is used to physically understand the mode-locking and in combination with an analytical description allows the identification of mode-locked regimes. The presented results open the route towards compact, high repetition-rate femto-second sources, where the operating wavelength is not bound to the availability of laser gain media or saturable absorbers. The smooth optical soliton spectra are essential to frequency domain applications such as channel generators in advanced telecommunication or in fundamental studies such as astrophysical spectrometer calibration[12, 16–18]. Moreover, femto-second pulses in conjunction with external broadening provide a viable route to a microresonator RF-to-optical link[5, 19].
Strategies Men Use to Cope with Stress Caused by Severe Obesity: A Qualitative Study

Abstract This qualitative study sought to explore and describe the coping strategies obese men use, as well as the lived experience of being obese. A phenomenological approach, symbolic interactionism and life course perspectives were used as theoretical points of departure. Experiences of being obese were described through three individual, in-depth, unstructured interviews. Emotion-focused coping strategies like blaming, denial and reappraisal, as well as avoidance were used while problem-focused coping strategies consisted of physical activity, weight loss diets and wearing appropriate clothes. Cognitive appraisals gave rise to certain emotions and feelings that their self and well-being were at risk and need to be dealt with. Along the life course they developed a specific coping trajectory. Identification of coping strategies and better awareness of the lived experience of obese men may enhance the knowledge of professionals, family members as well as parents who need to support them. It also provided tools to help vulnerable obese people deal with the consequences of stigma associated with it.
Casadio–Fabbri–Mazzacurati black strings and braneworld-induced quasars luminosity corrections

This paper aims to evince the corrections on the black string warped horizon in the braneworld paradigm, and their drastic physical consequences, as well as to provide subsequent applications in astrophysics. Our analysis concerning black holes on the brane departs from the Schwarzschild case, where the black string is unstable to large-scale perturbation. The cognizable measurability of the black string horizon corrections due to braneworld effects is investigated, as well as their applications in the variation of quasars luminosity. We delve into the case wherein two solutions of Einstein’s equations proposed by Casadio, Fabbri and Mazzacurati, regarding black hole metrics presented a post-Newtonian parameter measured on the brane. In this scenario, it is possible to analyze purely the braneworld corrected variation in quasars luminosity, by an appropriate choice of the post-Newtonian parameter that precludes Hawking radiation on the brane: the variation in quasars luminosity is uniquely provided by pure braneworld effects, as the Hawking radiation on the brane is suppressed.
BAO extractor: bias and redshift space effects

We study a new procedure to measure the sound horizon scale via Baryonic Acoustic Oscillations (BAO). Instead of fitting the measured power spectrum (PS) to a theoretical model containing the cosmological informations and all the nonlinear effects, we define a procedure to project out (or to “extract”) the oscillating component from a given nonlinear PS. We show that the BAO scale extracted in this way is extremely robust and, moreover, can be reproduced by simple theoretical models at any redshift. By using N-body simulations, we discuss the effect of the nonlinear evolution of the matter field, of redshift space distortions and of scale-dependent halo bias, showing that all these effects can be reproduced with sub-percent accuracy. We give a one-parameter theoretical model based on a simple (IR) modification of 1-loop perturbation theory, which reproduces the BAO scale from measurements of halo clustering in redshift space at better than 0.1% level and does not need any external UV input, such as coefficients measured from N-body simulations.
Thinning effects on foliar elements in eastern hemlock: implications for managing the spread of the hemlock woolly adelgid

Stand thinning is being tested as a means to limit the impacts of the invasive hemlock woolly adelgid (HWA; Adelges tsugae Annand) on eastern hemlock (Tsuga canadensis (L.) Carriere). The efficacy of this strategy may be reduced if thinning increases hemlock foliar nutrients because HWA densities are correlated with foliar concentrations of N, P, K, Ca, and Mn. We determined foliar N, P, K, Ca, and Mn concentrations in 1-year-old and all other (older) needles prior to and for 4 years after thinning in northwestern Pennsylvania stands of eastern hemlock without HWA. Average foliar concentrations in 1-year-old needles were 1.30–1.80 g N·100 g−1, 1300–1700 mg P·kg−1, 4200–6300 mg K·kg−1, 2500–5200 mg Ca·kg−1, and 2393 μg Mn·g−1. N, P, and K decreased, Ca increased, and Mn first increased and then stabilized. Thinning by itself did not affect the tested foliar nutrients. The interaction between treatment and year was significant and evident in temporal trajectories of foliar N and K. However, the differences .
Dropout Variational Inference Improves Object Detection in Open-Set Conditions

One of the biggest current challenges of visual object detection is reliable operation in open-set conditions [1]. In contrast to closed-set conditions, where it is assumed that the objects seen during deployment are the same as during training, a vision system operating in open-set conditions [2, 3] will encounter objects of novel classes that were not part of the training dataset. Robust object detection in such conditions is of paramount importance for robotics, as a robot that acts on the output of an unreliable visual perception system can perform catastrophic actions.
FORMING OF RELIABILITY MODEL IN ORDER TO EVALUATE THE OPERATOR ' S ACTIVITY RISK UDC 62 . 51

In this paper the expert ranking method has been applied in the process of forming the operator's reliability model in the control centres of the coal mines in Serbia. The expert group determined the important reliability/risk factors and estimated their influence on the operator's reliability. The ranking process and determination of concordance coefficient has confirmed the uniformity of expert group opinions. Weight coefficients of reliability factors have been determined using the iterative procedure, which includes different competencies of experts. On the basis of these results the reliability model of operator-dispatcher has been defined.
Adolescent Stress: Preparing for High-Stakes Tests

Tests with serious consequences are known to cause test anxiety, and thus are widely investigated. Competitive entrance exams are sources of stress for the students in Turkey—a developing country with a very young population. Exams are experienced as a long process for the whole family as they require a thorough preparation. In most studies, test anxiety is operationalized as a feeling when person confronts an evaluative situation. Nevertheless, important tests have long preparation periods that may be as stressful as confronting the tests. The anxiety experienced during the preparation can be coined as preparation anxiety. The main interest of the present study has been to substitute preparation anxiety for test anxiety in a transactional model of test anxiety and to investigate its relationship with appraisal, coping and outcome.
TGFBR 1 * 6 A is a potential modifier of migration and invasion in colorectal cancer cells

Type 1 transforming growth factor β receptor (TGFBR1)*6A, a common hypomorphic variant of TGFBR1, may act as a susceptibility allele in colorectal cancer. However, the contribution of TGFBR1*6A to colorectal cancer development is largely unknown. To test the hypothesis that TGFBR1*6A promotes colorectal cancer invasion and metastasis via Smad-independent transforming growth factor-β (TGF-β) signaling, the effect of TGFBR1*6A on the invasion of colorectal cancer cells was assessed. pCMV5-TGFBR1*6A-HA plasmids were transfected into SW48 and DLD-1 cells by Lipofectamine-mediated DNA transfection. The effect of TGF-β1 on the proliferation of SW48 and DLD-1 cells transfected with TGFBR1*6A was determined by MTT assay. The effects of the TGF-β1 on the invasion of the transfected SW48 and DLD-1 cells were determined using Matrigel-coated plates. Transforming migrating chambers were used to determine the effects of TGF-β1 on the migration of the transfected SW48 and DLD-1 cells. Western blot analysis was used to determine the expression of phosphorylated (p-) extracellular-signal-regulated kinase (ERK), p-P38 and p-SMAD family member 2 in SW48 cells. Using transfected TGFBR1*6A SW48 and DLD-1 cell lines our group demonstrated that, in comparison with TGFBR1*9A, TGFBR1*6A is capable of switching TGF-β1 growth-inhibitory signals into growth‐stimulatory signals which significantly increased the invasion of SW48 and DLD-1 cells. Functional assays indicated that TGFBR1*6A weakened Smad-signaling but increased ERK and p38 signaling, which are crucial mediators of cell migration and invasion. From this, it was possible to conclude that TGFBR1*6A enhanced SW48 cell migration and invasion through the mitogen-activated protein kinase pathway and that it may contribute to colorectal cancer progression in a TGF-β1/Smad signaling-independent manner. This suggests that TGFBR1*6A may possess oncogenic properties and that it may affect the migration and invasion of colorectal cancer cells.
CHAPTER 5 R proteins : molecular switches controlled by their nucleotide binding status

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Quotas for Women in the Brazilian Legislative System

This paper evaluates the initial results of the application of gender quotas in the Brazilian legislative competition. It is based on research beginning in 1996, and it aims to assess both the process and the impact of the quota system. The results of the 1992 municipal elections, prior to the adoption of quotas, are compared with those of 1996 and 2000, after the quota system was in place. The Federal Chamber and the State Assemblies are studied via a comparison of four elections, in 1990, 1994, 1998 and 2002. The first two elections preceded the adoption of quotas.