Miracle-dz/UniFAR-FTUs huggingface dataset:
Rudimentary Horn Rupture: A Case Report

Rudimentary horn is a developmental anomaly of the uterus, and pregnancy in a non-communicating rudimentary horn is very difficult to diagnose before it ruptures. As the fetus enlarges in the rudimentary horn, the chances of rupture in the first or second trimester are increased, since the uterine cavity is the only place properly designed to expand and accommodate the developing fetus. Catastrophic hemorrhage results in increased maternal and perinatal mortality and morbidity. To date, management of such cases remains a challenge due to diagnostic dilemma. Expertise in ultrasonography and early resort to surgical management are lifesaving in such cases. A case of undiagnosed rudimentary horn pregnancy presented to the Nizwa regional referral hospital in shock with features of acute abdomen, and the diagnosis was confirmed at laparotomy.
Attitude, knowledge and behaviour towards evidence-based medicine of physical therapists, students, teachers and supervisors in the Netherlands: a survey.

RATIONALE, AIMS AND OBJECTIVES Evidence-based medicine (EBM) has gained widespread acceptance in physical therapy. However, because little is known about the attitudes, knowledge and behaviour of physical therapists towards EBM, and their participation in research to generate EBM, we explored these aspects among physical therapy students, teachers, supervisors and practising physical therapists. METHODS This is a cross-sectional survey in which participants completed a web-based questionnaire to determine their attitudes, knowledge and behaviour regarding EBM, and their participation in research. RESULTS Questionnaires were sent to 814 participants of which 165 were returned. The overall mean score for attitude was 4.3 [standard deviation (SD) 1.0; range 1-7], which indicates a weak positive attitude. Teachers scored the highest (4.9, SD 1.2) and students the lowest (4.1, SD 0.8). Although most participants had some understanding of the technical terms used in EBM, only teachers felt able to explain these terms to others. Of the students, 45% rated their perceived EBM knowledge as bad and 45% as average, whereas 78% of the teachers considered that they had good knowledge. To answer clinical questions, most students generally use textbooks (96%) and the opinion of their supervisors (87.7%). CONCLUSIONS There is a weak positive attitude of physical therapists, teachers, supervisors and students towards participating in research in general practice, but there is a lack of knowledge and active behaviour regarding EBM, especially among physical therapy students.
Improved Dynamic Response of DC to DC Converter Using Hybrid PSO Tuned Fuzzy Sliding Mode Controller

DC/DC switching converters are widely used in numerous appliances in modern existence. In this paper, the dynamic and transient response of phase shift series resonant DC/DC converter are improved using hybrid particle swarm optimization tuned fuzzy sliding mode controller under starting and load step change conditions. The aim of the control is to regulate the output voltage beneath the load change. The model of the hybrid particle swarm optimization tuned fuzzy sliding mode controller is implemented using Sim Power Systems toolbox of MATLAB SIMULINK. Performance of the proposed dynamic novel control under step load change condition is investigated.
Meat consumption, N-acetyl transferase 1 and 2 polymorphism and risk of breast cancer in Danish postmenopausal women

The aim of this study was to investigate whether polymorphisms in N-acetyl transferase 1 and 2 modify the association between meat consumption and risk of breast cancer. A nested case–control study was conducted among 24 697 postmenopausal women included in the ‘Diet, Cancer and Health’ cohort study (1993–2000). Three hundred and seventy-eight breast cancer cases were identified and matched to 378 controls. The incidence rate ratio (95% confidence interval) for breast cancer was 1.09 (1.02–1.17) for total meat, 1.15 (1.01–1.31) for red meat and 1.23 (1.04–1.45) for processed meat per 25 g daily increment in intake. Compared with slow acetylators, the IRR (95% confidence interval) among fast N-acetyl transferase 1 acetylators was 1.43 (1.03–1.99) and 1.13 (0.83–1.54) among intermediate/fast N-acetyl transferase 2 acetylators. Interaction analyses revealed that the positive associations between total meat intake and red meat intake and breast cancer risk were confined to intermediate/fast N-acetyl transferase 2 acetylators (Pinteraction=0.03 and 0.04). Our findings support an association between meat consumption and breast cancer risk and that N-acetyl transferase 2 polymorphism has a modifying effect on the association, indicating that the association is confined to only genetically susceptible women.
A New Nested Polymerase Chain Reaction Method Very Efficient in Detecting Plasmodium and Haemoproteus Infections From Avian Blood

Recently, several polymerase chain reaction (PCR)–based methods for detection and genetic identification of haemosporidian parasites in avian blood have been developed. Most of these have considerably higher sensitivity compared with traditional microscope-based examinations of blood smears. These new methods have already had a strong impact on several aspects of research on avian blood parasites. In this study, we present a new nested PCR approach, building on a previously published PCR method, which has significantly improved performance. We compare the new method with some existing assays and show, by sequence-based data, that the higher detection rate is mainly due to superior detection of Plasmodium spp. infections, which often are of low intensity and, therefore, hard to detect with other methods.
Effects of corticosterone on response consolidation and retrieval in the forced swim test.

In the forced swimming test, adrenal hormones regulate immobility time during a test swim given 24 hr after the initial training swim (e.g., the deficit in adrenalectomized animals is reduced when animals are given corticosterone [B] immediately after the training session). In this study, adrenalectomy decreased and B restored immobility during the test swims. The effects of adrenalectomy were completely reversed by 1 mg/kg doses of B, which results in plasma B levels that are comparable to values under basal resting conditions. Higher doses of B had no further effect. B given before or immediately after training partially reversed the effects of adrenalectomy. The complete reversal of the effects of adrenalectomy, however, required the presence of B during both training and testing, suggesting that B plays a role in the consolidation-retention and retrieval of the immobility response.
Brain Activation during Working Memory after Traumatic Brain Injury in Children

Eight children with moderate to severe traumatic brain injury (TBI) and eight matched, uninjured control children underwent fMRI during an N-back task to test effects of TBI on working memory performance and brain activation. Two patterns in the TBI group were observed. Patients whose criterion performance was reached at lower memory loads than control children demonstrated less extensive frontal and extrafrontal brain activation than controls. Patients who performed the same, highest (3-back) memory load as controls demonstrated more frontal and extrafrontal activation than controls. Our findings of performance and brain activation changes in children after TBI await longitudinal investigation.
A Case of Occupational Bronchial Asthma and Contact Dermatitis Caused by ortho‐Phthalaldehyde Exposure in a Medical Worker

Ortho-phthalaldehyde (OPA) has been considered a powerful disinfectant for medical devices because it is more effective against glutaraldehyde (GA)-resistant mycobacteria, less irritating and faster-acting than GA, and does not require an activation step. Since many nurses have developed dermatitis and bronchial asthma as a result of GA exposure , the use of OPA as an alternative to GA is increasing. Although the lowest published lethal dose (LDLo ) of OPA is reported to be 7 mg/kg in the mouse, few safety tests on OPA have been performed. There have been reports of chemical burn and anaphylaxis 10) in patients which were caused by OPA. However, a company producing it advertises that OPA is much safer than GA for workers because its vapor pressure is lower and solutions of it are thinner than those of GA. In this report, we describe the first case of occupational bronchial asthma and contact dermatitis thought to be caused by OPA exposure in an endoscopy unit, and we also report the OPA concentrations measured in the air at the patient’s workplace.
Time delay control of flyback CCM inverter for PV power applications

A flyback inverter in continuous conduction mode (CCM) operation has simple structure, high efficiency, and low cost. But, in CCM operation, the transfer function from the control input to the output current of the flyback inverter has right-half-plane zero, which causes slow and delayed response. To achieve fast response, Time-delay controller (TDC) is proposed, which consists of a linear controller and a time delay estimator. The time-delay estimator is one of the simplest and efficient estimator that can estimate the unknown dynamics and disturbance. The linear controller enables the closed loop system to achieve the desired dynamics. Numerical simulations are performed to validate the proposed control approach.
Effects of Parental Socio-Economic Conditions on Facial Attractiveness

Socio-economic conditions during early life are known to affect later life outcomes such as health or social success. We investigated whether family socio-economic background may also affect facial attractiveness. We used the Wisconsin Longitudinal Study (n = 8434) to analyze the association between an individual's parental socioeconomic background (in terms of father's highest education and parental income) and that individual's facial attractiveness (estimated by rating of high school yearbook photographs when subjects were between 17 and 20 years old), controlling for subjects' sex, year of birth, and father's age at subjects' birth. Subjects' facial attractiveness increased with increasing father's highest educational attainment as well as increasing parental income, with the latter effect being stronger for female subjects as well. We conclude that early socio-economic conditions predict, to some extent, facial attractiveness in young adulthood.
Construction of a complete genomic library of Saccharomyces cerevisiae and physical mapping of chromosome XI at 3·7 kb resolution

A consortium of European laboratories has been organized to systematically sequence the genome of Saccharomyces cerevisiae. As part of the BIOTECH program aimed at sequencing chromosomes XI and II, we have constructed a total genomic library of yeast strain FY1679 (a direct S288C derivative) into cosmid vectors pWE15 and pOU61cos. Primary clones from four independent libraries totalling 190 genome equivalents have been stored at −80°C.
Post-Earnings Announcement Drift: Timing and Liquidity Costs

The persistence of the post-earnings announcement drift leads many to believe that trading barriers prevent knowledgeable investors from eliminating it. For example, Bhushan (1994) contends that sophisticated investors quickly drive prices to within trading costs of efficient values. We examine two factors not previously addressed in the literature: the exact timing of the announcements and liquidity costs. Specifically, we compare the profits generated by transacting immediately following the announcement and at the close of the actual announcement day to the common practices of assuming trades at the close on the Compustat date or the following day. We further investigate the impact of liquidity costs on the drift by examining actual quotes available to investors. Under a wide range of timing and cost assumptions our results leave little doubt that between 1993 and 2002 an investor could have earned hedged-portfolio returns of at least 14% per year after trading costs.
Frequencies of allele groups HLA‐A, HLA‐B and HLA‐DRB1 in a population from the northwestern region of São Paulo State, Brazil

The aim of this study was to estimate the HLA‐A, HLA‐B and HLA‐DRB1 allele groups frequencies in a population of 1559 volunteer bone marrow donors from the northwestern region of São Paulo State grouped according to ethnicity. An additional objective was to compare the allele frequencies of the current study with data published for other Brazilian populations. The allele groups were characterized by the PCR‐rSSO method using Luminex® technology. Twenty HLA‐A, 32 HLA‐B and 13 HLA‐DRB1 allele groups were identified. The most common allele groups in European descent and mixed African and European descent samples were HLA‐A*02, HLA‐B*35 and HLA‐DRB1*13, while HLA‐A*02, HLA‐B*35 and HLA‐DRB1*11 were more common in African descent samples. The HLA‐A*23, HLA‐A*36, HLA‐B*58 and HLA‐B*81 allele groups were more common in sample from African descent than European descent, and the HLA‐DRB1*08 was more common in mixed African and European descent than in European descent. Allele group frequencies were compared with samples from other Brazilian regions. The HLA‐A*30 and HLA‐A*23 were more common in this study than in the populations of Rio Grande do Sul and Paraná; and the HLA‐A*01, HLA‐B*18, HLA‐B*57 and HLA‐DRB1*11 were more common in this study than in the population of Piauí. The least frequent allele groups were HLA‐A*31, HLA‐B*15, HLA‐B*40 and HLA‐DRB1*08 for the population of Piauí, HLA‐A*01 and HLA‐A*11 for Parana, HLA‐A*02 and ‐A*03 for Rio Grande do Sul and HLA‐DRB1*04 for Paraná, Rio Grande do Sul and Piauí. These data provide an overview on the knowledge on HLA diversity in the population of the northwestern region of São Paulo State and show that the genes of this system are useful to distinguish different ethnic groups.
An Architecture of Problem-oriented E-learning System for Product After-sales Service: Design and Application

Customers expect to obtain the personalized knowledge when they encounter some problems during the use of product, however, the traditional after-sales service modes are difficult to meet this kind of demand. This paper adopts process-based design method to construct the problem-oriented e-learning process model for product after-sales service and analyze the functions of realizing this process, and then problem-oriented e-learning system architecture is designed for product after-sales service. According to the different characteristics of two categories firms, this paper respectively give the system architecture application strategies, namely the integration strategy of existing information systems with e-learning system for more mature firms in IT application, and the configuration of simple and practical architecture of e-learning system for small and micro firms.
Mycobacterium leprae and Leprosy: A Compendium

Leprosy is a chronic infectious disease caused by Mycobacterium leprae, which was discovered by G.H. A. Hansen in 1873. M. leprae is an exceptional bacterium because of its long generation time and no growth in artificial media. Entire sequencing of the bacterial genome revealed numerous pseudogenes (inactive reading frames with functional counterparts in M. tuberculosis) which might be responsible for the very limited metabolic activity of M. leprae. The clinical demonstration of the disease is determined by the quality of host immune response. Th1‐type immune response helps to kill the bacteria, but hosts are encroached upon when Th2‐type response is predominant. The bacteria have affinity to the peripheral nerves and are likely to cause neuropathy. M. leprae/laminin‐α2 complexes bind to α/β dystroglycan complexes expressed on the Schwann cell surface. WHO recommends a chemotherapy protocol [multidrug therapy (MDT)] which effectively controls the disease and contributes to the global elimination program. Leprosy has been stigmatized throughout history, and recent topics regarding the disease in Japan are also discussed.
PSO based parametric object recognition

In this paper, we propose an object recognition technique based on particle swarm optimization. Our technique reduces the complexity of the Hough transform and the rigidity of template matching via cross correlation, while harnessing the robustness of both methods. To demonstrate its effectiveness, the proposed technique has been applied for ellipsoid detection in three-dimensional images and satisfactory results have been obtained. The detected object is described by a set of parameters, which can be used for further processing. In addition, our technique can be adapted for the detection of other objects, provided that they can be represented by a set of parameters.
Can the faint submillimetre galaxies be explained in the Λ cold dark matter model

We present predictions for the abundance of submillimetre galaxies (SMGs) and Lyman-break galaxies (LBGs) in the Λ cold dark matter cosmology. A key feature of our model is the self-consistent calculation of the absorption and emission of radiation by dust. The new model successfully matches the LBG luminosity function, as well as reproducing the properties of the local galaxy population in the optical and infrared. The model can also explain the observed galaxy number counts at 850 μm, but only if we assume a top-heavy initial mass function for the stars formed in bursts. The predicted redshift distribution of SMGs depends relatively little on their flux over the range 1–10 mJy, with a median value of z≈ 2.0 at a flux of 5 mJy, in good agreement with the recent measurement by Chapman et al. The counts of SMGs are predicted to be dominated by ongoing starbursts. However, in the model these bursts are responsible for making only a few per cent of the stellar mass locked up in massive ellipticals at the present day.
Glutathione redox regulates lipopolysaccharide‐induced IL‐12 production through p38 mitogen‐activated protein kinase activation in human monocytes: role of glutathione redox in IFN‐γ priming of IL‐12 production

We examined whether changes in intracellular reduced (GSH) or oxidized (GSSG) glutathione of human monocytes regulate lipopolysaccharide (LPS)‐induced IL‐12 production and defined the molecular mechanism that underlies glutathione redox regulation. Monocytes exposed to glutathione reduced form ethyl ester (GSH‐OEt) or maleic acid diethyl ester (DEM) increased or decreased the intracellular GSH/GSSG ratio, respectively. LPS‐induced IL‐12 production and p38 mitogen‐activated protein (MAP) kinase activation were enhanced by GSH‐OEt but suppressed by DEM. Selective p38 inhibitors showed that p38 promoted GSH‐OEt‐enhanced IL‐12 production. Furthermore, IFN‐γ priming increased the GSH/GSSG ratio and enhanced IL‐12 production through p38, and DEM negated the priming effect of IFN‐γ on p38 activation and IL‐12 production as well as on the GSH/GSSG ratio. These findings reveal that glutathione redox regulates LPS‐induced IL‐12 production from monocytes through p38 MAP kinase activation and that the priming effect of IFN‐γ on IL‐12 production is partly a result of the glutathione redox balance.
A comparative review of estimates of FDR in small microarray experiments

The focus of this paper is to illustrate and compare three recently suggested methods for the identification of differentially expressed genes and estimation of the false discovery rate (FDR) and to inversigate whether these FDR estimation methods are biased when we have a small sample size of 3 subjects per group. The methods are estimation of FDR based on averaging of fdr1d (FDR.avg), FDR estimation based on averaging of fdr2d (FDR.avg.fdr2d) and direct estimation of FDR using p-values (FDR.p). The properties are studied in a simulation experiment and a real data example. The comparison results shows that FDR.avg.fdr2d performs better than FDR.p and FDR.avg. The results further show the limitation of performance of the methods in very small sample size such as three subjects per group indicating the importance of developing a new FDR estimation procedure which works well under a situation of small sample size and unequal group variances.
Multidimensional alcoholism typologies: could they guide clinical practice? Results from a 3-month prospective study

Abstract Objective. The current nosological classifications may describe a syndrome of “alcoholism” that is too heterogeneous to produce prognostic models for clinical management. Multidimensional alcoholism typologies (ATs) could represent a valuable paradigm in the search for targeted treatment. The main goal of this study was to evaluate the clinical implications of 3 empirically-validated ATs, focusing on various measures of clinical performance. Method. This was a 3-month naturalistic study in which drinking status, and participation in the clinical protocol and group psychotherapy were recorded and used as indicators of treatment performance. The clinical profiles of the subtypes were also compared and graphically presented. Alcohol-dependent outpatients were classified according to the Cloninger, Lesch, and NETER typologies. Results. The results showed that the type II (Cloninger), type IV (Lesch), and sociopathic and addictopathic (NETER) subgroups showed a worse outcome in terms of abstinence rates and clinical healthcare resource use. Conclusions. Our findings point to the need to differentiate multidimensional alcoholism subtypes before planning the clinical management of alcohol use disorders.
Absorption of circularly polarized x rays in iron.

The transmission of synchrotron radiation through magnetized iron at energies above the K-absorption edge shows relative differences for right and left circular polarization of several times 10/sup -4/. The observed spin dependence of the near-edge photoabsorption is proportional to the difference of the spin densities of the unoccupied bands. In the extended absorption region up to 200 eV above the Fermi level a small spin-dependent absorption is observed and thus is expected to give information on the magnetic neighborhood of the absorbing atom.
Automatic Refinement of Linguistic Rules for Tagging

This paper describes an approach to POS tagging based on the automatic refinement of manually written linguistic tagging rules. The refinement was carried out by means of a learning algorithm based on decision trees. The tagging rules work on ambiguity classes: each input word undergoes a morphological analysis and a set of possible tags is returned. The set of tags determines the ambiguity class: the suitable subset of tagging rules is applied and a single tag is returned. This method can be applied both with the original set of manual rules and with the set of refined rules. The experiments have been performed on the Italian language. The results show that the refined set reduces the tagging error of about 17%. The noticeable feature of the approach is that the original set of rules is not modified, so that they retain their linguistic value, but new rules are added to handle problematic cases.
Oscillator radiated susceptibility analysis by estimating the added phase noise

In this paper the radiated susceptibility of oscillators is investigated in electromagnetic polluted environment. Oscillator is one the most important constituting block in every RF communication device and its operation dramatically defines the total system performance. The radiated susceptibility of oscillator has been analyzed in term of added phase noise to the intrinsic phase noise of the output spectrum, due to external electromagnetic wave illumination. As a source of threat, the electromagnetic radiation output of WiMax antenna is considered and the output oscillation spectrum is investigated. The method is verified by full wave simulations of a PCB mounting a real oscillator in CST software environment. In addition, analytic verification is done to prove the sensitivity of the oscillator while it has its normal operation.