Miracle-dz/UniFAR-FTUs huggingface dataset:
Optimum Scheme Design and Analysis of Accelerated Life Test for Sealed Electromagnetic Relay

Taking sealed electromagnetic relays as the research object,with the failure mechanism analyzed and the maximum likelihood theory applied,in order to minimize sealed electromagnetic relays' incremental variance of median life estimate on the typical operating condition,the optimal scheme model of accelerated life test for sealed electromagnetic relays which complied Weibull distribution was set up.And its variance of mean and standard deviation were taken as the optimization criterion.Lastly,the simulation results of sealed electromagnetic relays' bivariate step-stress accelerated life test were discussed to illustrate the proposed criteria.The simulation results showed that the proposed optimum plan was robust.The optimum test scheme could realize fast evaluation of sealed electromagnetic relays' reliability under the effect of temperature and humidity.
Left Atrial Reservoir Strain-Based Left Ventricular Diastolic Function Grading and Incident Heart Failure in Hypertrophic Cardiomyopathy

Background: The echocardiographic assessment of left ventricular (LV) diastolic dysfunction (LVDD) in patients with hypertrophic cardiomyopathy is complex and not well-established. We investigated whether the left atrial reservoir strain (LARS) could be used to categorize LVDD and whether this grading is predictive of heart failure (HF) events in hypertrophic cardiomyopathy. Methods: A total of 414 patients with hypertrophic cardiomyopathy (aged 58.3±12.8 years; 65.7% male) were categorized using LARS-defined LVDD (LARS-DD) grades: ≥35% (grade 0), ≥24% to <35%, ≥19% to <24%, and <19% (grade 3). Patients were followed for a median of 6.9 years to assess hospitalization for HF or HF-related death. Results: An increase in LARS-DD grade was associated with worse conventional echocardiographic parameters of LVDD, such as lower e′, higher E/e′ ratio, greater maximum tricuspid regurgitation velocity, and restrictive mitral inflow pattern. Higher LARS-DD grade was also associated with parameters reflecting increased LV filling pressure, such as greater LV wall thickness, greater extent of fibrosis, obstructive physiology, and decreased LV longitudinal strain. Furthermore, higher LARS-DD grade was associated with worse HF-free survival (log-rank P<0.001). Patients with LARS-DD grades 0, 1, 2, and 3 showed 10-year HF-free survival of 100%, 91.6%, 84.1%, and 67.5%, respectively. LARS-DD grade was an independent predictor of HF events after adjusting for clinical and echocardiographic variables (hazard ratio, 1.53 [95% CI, 1.03–2.28], per 1-grade increase). The LARS-DD grade also had incremental prognostic value for incident HF events over the traditional echocardiographic LVDD parameters and grading system. The prognostic value of advanced LARS-DD grade was consistent in sensitivity analyses and various patient subgroups. Conclusions: LARS can be used as a simple single or supplemental index to categorize LV diastolic function and predict HF events in hypertrophic cardiomyopathy.
Pilot Study on Predictive Traits of Fresh Maize Hybrids for Estimating Milk and Biogas Production

Farmers need information on which maize hybrid is best and under what conditions. They demand that this information be clear, simple and easily understood. This study aims to estimate the potential for milk production (MPP) and the biochemical methane potential (BMP) production from fresh maize hybrids. Using these indicators from fresh maize, information on the differences between hybrids can be effectively obtained, albeit with some of the shortcomings of this proposed method. Samples of fresh maize plants (n = 384) from four hybrids were evaluated at two locations over four consecutive years (from 2018 to 2021). The dry matter content, averaged across all hybrids, all years and both locations, was 371 ± 42.3 g.kg−1. The colder and wetter the year, the significantly higher the starch content, lower the amylase-treated neutral detergent fibre content (aNDF) and lower the crude protein (CP), which was reflected in lower BMP. Weather did not significantly affect the net energy of lactation (NEL) or MPP values. The location significantly affected all monitored indicators, except BMP. The earlier the hybrid was at harvest time, the lower the NEL and MPP but the higher BMP contents were. This study is preliminary and must be repeated with more hybrids and under more different conditions.
On the Incipient Indicial Lift of Thin Wings in Subsonic Flow: Acoustic Wave Theory with Unsteady Three-Dimensional Effects

: Enhanced approximate expressions for the incipient indicial lift of thin wings in subsonic potential ﬂow are presented in this study, featuring explicit analytical corrections for the unsteady downwash. Lifting-line and acoustic-wave theories form the basis of the method, within an effective synthesis of the governing physics, which grants a consistent generalised framework and uniﬁes previous works. The unsteady ﬂow perturbation consists of a step-change in angle of attack or a vertical sharp-edged gust. The proposed model is successfully evaluated against numerical results in the literature for the initial airload development of elliptical and rectangular wings with a symmetric aerofoil, considering several aspect ratios and Mach numbers. While nonlinear downwash and compressibility terms demonstrate marginal (especially for the case of a travelling gust), both linear and nonlinear geometrical effects from a signiﬁcant taper ratio, sweep angle or curved leading-edge are found to be more important than linear downwash corrections (which are crucial for the circulation growth at later times instead, along with linear compressibility corrections). The present formulae may then be used as a rigorous reduced-order model for validating higher-ﬁdelity tools and complex simulations in industrial practice, as well as for estimating parametric sensitivities of unsteady aerodynamic loads within the preliminary design of aircraft wings in the subsonic regime.
Modelling and parameter estimation of Li-ion battery in a fuel cell vehicle

Considering automotive dynamics and economics ,fuel cell and battery hybrid power system is a major plan . Based on the constant current and pulse current datum ,the static and dynamic characters of Li-ion battery were analyzed ,and a lin-ear model in PNGV battery test manual was adopted . At last a method of on-line parameter estimation for this model was presented.Theoretical analysis and simulation study show that PNGV model is suitable for Li-ion power battery,and as long as voltage and current measurement precision are enough,the above mentioned method is effective.
Sleep-related breathing disorders - 3 How to reach a diagnosis in patients who may have the sleep apnoea/hypopnoea syndrome

90-Oxygen saturation over an eight hour night (x axis = time) in a patient with moderately severe sleep apnoealhypopnoea syndrome with 23 apnoeas + hypopnoeaslhour of sleep, 25 arousalslhour ofsleep, and a mean sleep latency of 1 4 minutes overfive daytime sleep opportunities. This shows the relative normality of an oxygen saturation trace in a patient with severe consequences of respiratory related arousals.
Enhancement sensory, physicochemical and antioxidant properties of moringa functional beverages

The Moringa tree is known as the miracle tree and its leaves are a source of nutrition, its rich in minerals, vitamins and antioxidants. This study aims to prepare an accepted functional beverage from Moringa by adding it to pineapple juice and ginger extract. In this study, the chemical composition, minerals and antioxidants "phenols, flavonoids and total carotenoids" were estimated in Moringa leaves, then a sensory evaluation of these beverages was conducted. Then the physical properties (TSS, TA and pH) and antioxidant properties (total phenolic, total flavonoid and radical scavenging activity by DPPH) were estimated. Through the study, it was found that the ratios of 10-15% Moringa extract, 90 and 85% pineapple juice, and Moringa tea blended with ginger extract 2% was optimal and most amenable to the consumers. Additionally, mixing Moringa extract with pineapple juice increased the total phenol content and improved the antioxidant properties of the beverage.From these study, it will be possible to improve the sensory acceptance of Moringa leaves when mixed with juices and herbs and convert them into functional beverages acceptable sensory while increasing the characteristics and nutritional value for the largest number of consumers. flavonoids, and carotenoids, each of which are known antioxidants. The results of proximate analysis, and phytochemical composition imply that Moringa
Unique Properties of Surface-Functionalized Nanoparticles for Bio-Application: Functionalization Mechanisms and Importance in Application

This review tries to summarize the purpose of steadily developing surface-functionalized nanoparticles for various bio-applications and represents a fascinating and rapidly growing field of research. Due to their unique properties—such as novel optical, biodegradable, low-toxicity, biocompatibility, size, and highly catalytic features—these materials are considered superior, and it is thus vital to study these systems in a realistic and meaningful way. However, rapid aggregation, oxidation, and other problems are encountered with functionalized nanoparticles, inhibiting their subsequent utilization. Adequate surface modification of nanoparticles with organic and inorganic compounds results in improved physicochemical properties which can overcome these barriers. This review investigates and discusses the iron oxide nanoparticles, gold nanoparticles, platinum nanoparticles, silver nanoparticles, and silica-coated nanoparticles and how their unique properties after fabrication allow for their potential use in a wide range of bio-applications such as nano-based imaging, gene delivery, drug loading, and immunoassays. The different groups of nanoparticles and the advantages of surface functionalization and their applications are highlighted here. In recent years, surface-functionalized nanoparticles have become important materials for a broad range of bio-applications.
Emerging Methods of Monitoring Volatile Organic Compounds for Detection of Plant Pests and Disease

Each year, unwanted plant pests and diseases, such as Hendel or potato soft rot, cause damage to crops and ecosystems all over the world. To continue to feed the growing population and protect the global ecosystems, the surveillance and management of the spread of these pests and diseases are crucial. Traditional methods of detection are often expensive, bulky and require expertise and training. Therefore, inexpensive, portable, and user-friendly methods are required. These include the use of different gas-sensing technologies to exploit volatile organic compounds released by plants under stress. These methods often meet these requirements, although they come with their own set of advantages and disadvantages, including the sheer number of variables that affect the profile of volatile organic compounds released, such as sensitivity to environmental factors and availability of soil nutrients or water, and sensor drift. Furthermore, most of these methods lack research on their use under field conditions. More research is needed to overcome these disadvantages and further understand the feasibility of the use of these methods under field conditions. This paper focuses on applications of different gas-sensing technologies from over the past decade to detect plant pests and diseases more efficiently.
A Bayesian Approach to Describe and Simulate the pH Evolution of Fresh Meat Products Depending on the Preservation Conditions

Measuring the pH of meat products during storage represents an efficient way to monitor microbial spoilage, since pH is often linked to the growth of several spoilage-associated microorganisms under different conditions. The present work aimed to develop a modelling approach to describe and simulate the pH evolution of fresh meat products, depending on the preservation conditions. The measurement of pH on fresh poultry sausages, made with several lactate formulations and packed under three modified atmospheres (MAP), from several industrial production batches, was used as case-study. A hierarchical Bayesian approach was developed to better adjust kinetic models while handling a low number of measurement points. The pH changes were described as a two-phase evolution, with a first decreasing phase followed by a stabilisation phase. This stabilisation likely took place around the 13th day of storage, under all the considered lactate and MAP conditions. The effects of lactate and MAP on pH previously observed were confirmed herein: (i) lactate addition notably slowed down acidification, regardless of the packaging, whereas (ii) the 50%CO2-50%N2 MAP accelerated the acidification phase. The Bayesian modelling workflow—and the script—could be used for further model adaptation for the pH of other food products and/or other preservation strategies.
Understanding Young Adults’ Experiences of Recovering from Childhood Victimization

There are two objectives of this research. The first objective is to identify the process of overcoming childhood victimization, and the second objective is to identify the elements that facilitate the overcoming process. The participants of this research were from the researcher’s circle of acquaintances. A qualitative method was used to gather information on 7 young adults, aged between 20 and 25 years. The selected participants were interviewed face-to-face using semi-structured questions. The results obtained for the process of overcoming were learning to accept, reaching out to help oneself and reaching out to help others. As for the elements that help to facilitate the healing processes were support system, forgiveness and spirituality.
A Photography-based, Social Media Walking Intervention Targeting Autonomous Motivations for Physical Activity: Semistructured Interviews With Older Women

Background Older adult women are at risk for negative health outcomes that engaging in sustained physical activity can help prevent. However, promoting long-term maintenance of physical activity in this population has proven to be a challenge. Increasing autonomous motivations (ie, intrinsic, integrated, and identified regulations) for physical activity may facilitate enduring behavior change. Digitally delivered games for health that take a celebratory technology approach, that is, using technology to create new ways to experience valued behaviors and express valued beliefs, may be a useful way to target autonomous motivations for physical activity. Formative research with the target population is needed to design compelling intervention content. Objective The objective of this study is to investigate older adult women’s reactions to and thoughts about a photography-based, social media walking game targeting autonomous motivations for physical activity. Methods During an individual semistructured interview, a moderator solicited feedback from 20 older adult women (age range 65-74 years) as part of formative research to develop a social media game featuring weekly walking challenges. The challenges were designed to target autonomous motivations for physical activity. Interviews were audio-recorded and transcribed verbatim. Two reviewers conducted thematic content analysis on interview transcripts. Results We identified 3 overarching themes in qualitative data analysis. These reflected the playful experiences, value, and acceptability associated with the intervention challenges. Generally, participants understood what the challenges were asking them to do, proffered appropriate example responses, and indicated that the challenges would be enjoyable. Participants reported that the intervention content afforded many and varied playful experiences (eg, competition, discovery, exploration, expression, fellowship, humor, nurture, sensation). Further, participants indicated that the intervention increased their motivation for physical activity, occasioned meaningful shifts in perspective, increased their knowledge of various topics of interest, provided an opportunity to create valued connection with others, and provided health-related benefits. Participants suggested the intervention emphasize local history, nature, and cultural events. Conclusions The photography-based, social media walking game with relatively simple game mechanics was well received and judged to be apt to bring about a wide variety of emotive experiences. A clear, geographically specific identity emerged as a key driver of interest for intervention content. Taking a celebratory technology approach holds promise for targeting autonomous motivations for physical activity in older adult women.
Tools and Biomarkers for the Study of Retinal Ganglion Cell Degeneration

The retina is part of the central nervous system, its analysis may provide an idea of the health and functionality, not only of the retina, but also of the entire central nervous system, as has been shown in Alzheimer’s or Parkinson’s diseases. Within the retina, the ganglion cells (RGC) are the neurons in charge of processing and sending light information to higher brain centers. Diverse insults and pathological states cause degeneration of RGC, leading to irreversible blindness or impaired vision. RGCs are the measurable endpoints in current research into experimental therapies and diagnosis in multiple ocular pathologies, like glaucoma. RGC subtype classifications are based on morphological, functional, genetical, and immunohistochemical aspects. Although great efforts are being made, there is still no classification accepted by consensus. Moreover, it has been observed that each RGC subtype has a different susceptibility to injury. Characterizing these subtypes together with cell death pathway identification will help to understand the degenerative process in the different injury and pathological models, and therefore prevent it. Here we review the known RGC subtypes, as well as the diagnostic techniques, probes, and biomarkers for programmed and unprogrammed cell death in RGC.
Biomimetic Bi-Pedal Humanoid: Design, Actuation, and Control Implementation with Focus on Robotic Legs

The advancements made in technology over the past several decades have brought the field of humanoid robotics closer to integration into the everyday lives of humans. Despite these advances, the cost of these systems consistently remains high, thus limiting the environments in which these robots can be deployed. In this thesis, a pair of low-cost, bio-mimetic legs for a humanoid robot was developed with 12 degrees of freedom: three at the hip, one at the knee, and two at the ankle. Prior to developing the robot, a survey of the human-sized robotic legs released from 2006-2012 was conducted. The analysis included a summary of the key performance metrics and trends in series of human-sized robots. Recommendations were developed for future data reporting that will allow improved comparison of different prototypes. The design of the new robotic legs in this thesis utilized human anatomy data to devise performance parameters and select actuators. The developed system was able to achieve comparable ROM, size, weight, and torque to a six-foot tall human. Position and zero-moment point sensors were integrated for use in balancing, and a control architecture was developed. A model of the leg dynamics was created for designing balancing and walking algorithms. In addition, hydraulic actuators were evaluated for use in humanoid robotics, and testing was conducted in order to create a position control methodology. Finally, a predictive deadband controller was designed that was able to achieve accuracy of less than one degree using a valve with slow switching speed.
A Systematic Review of Ebstein’s Anomaly with Left Ventricular Noncompaction

Traditional definitions of Ebstein’s anomaly (EA) and left ventricular noncompaction (LVNC), two rare congenital heart defects (CHDs), confine disease to either the right or left heart, respectively. Around 15–29% of patients with EA, which has a prevalence of 1 in 20,000 live births, commonly manifest with LVNC. While individual EA or LVNC literature is extensive, relatively little discussion is devoted to the joint appearance of EA and LVNC (EA/LVNC), which poses a higher risk of poor clinical outcomes. We queried PubMed, Medline, and Web of Science for all peer-reviewed publications from inception to February 2022 that discuss EA/LVNC and found 58 unique articles written in English. Here, we summarize and extrapolate commonalities in clinical and genetic understanding of EA/LVNC to date. We additionally postulate involvement of shared developmental pathways that may lead to this combined disease. Anatomical variation in EA/LVNC encompasses characteristics of both CHDs, including tricuspid valve displacement, right heart dilatation, and left ventricular trabeculation, and dictates clinical presentation in both age and severity. Disease treatment is non-specific, ranging from symptomatic management to invasive surgery. Apart from a few variant associations, mainly in sarcomeric genes MYH7 and TPM1, the genetic etiology and pathogenesis of EA/LVNC remain largely unknown.
Mussel-Inspired and Bioclickable Peptide Engineered Surface to Combat Thrombosis and Infection

Thrombosis and infections are the two major complications associated with extracorporeal circuits and indwelling medical devices, leading to significant mortality in clinic. To address this issue, here, we report a biomimetic surface engineering strategy by the integration of mussel-inspired adhesive peptide, with bio-orthogonal click chemistry, to tailor the surface functionalities of tubing and catheters. Inspired by mussel adhesive foot protein, a bioclickable peptide mimic (DOPA)4-azide-based structure is designed and grafted on an aminated tubing robustly based on catechol-amine chemistry. Then, the dibenzylcyclooctyne (DBCO) modified nitric oxide generating species of 1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetic acid (DOTA) chelated copper ions and the DBCO-modified antimicrobial peptide (DBCO-AMP) are clicked onto the grafted surfaces via bio-orthogonal reaction. The combination of the robustly grafted AMP and Cu-DOTA endows the modified tubing with durable antimicrobial properties and ability in long-term catalytically generating NO from endogenous s-nitrosothiols to resist adhesion/activation of platelets, thus preventing the formation of thrombosis. Overall, this biomimetic surface engineering technology provides a promising solution for multicomponent surface functionalization and the surface bioengineering of biomedical devices with enhanced clinical performance.