Miracle-dz/UniFAR-FTUs huggingface dataset:
Analysis of EEG networks and their correlation with cognitive impairment in preschool children with epilepsy

Objective: Cognitive impairment (CI) is common in children with epilepsy and can have devastating effects on their quality of life and that of their family. Early identification of CI is a priority to improve outcomes, but the current gold standard of detection with psychometric assessment is resource intensive and not always available. This paper proposes a novel technique of network analysis using routine clinical electroencephalography (EEG) to help identify CI in children with early-onset epilepsy (CWEOE) (0-5 y.o.). Methods: We analyzed functional networks from routinely acquired EEGs of 51 newly diagnosed CWEOE from a prospective population-based study. Combinations of connectivity metrics (e.g. phase-slope index (PSI)) with sub-network analysis (e.g. cluster-span threshold (CST)) identified significant correlations between network properties and cognition scores via rank correlation analysis with Kendall’s τ. Predictive properties were investigated using a 5-fold cross-validated K-Nearest Neighbor classification model with normal cognition, mild/moderate CI and severe CI classes. Results: Phase-dependent connectivity metrics had higher sensitivity to cognition scores, with sub-networks identifying significant functional network changes over a broad range of spectral frequencies. Approximately 70.5% of all children were appropriately classified as normal cognition, mild/moderate CI or severe CI using CST network features. CST classification predicted CI classes 55% better than chance, and reduced misclassification penalties by half. Conclusions: CI in CWEOE can be detected with sensitivity at 85% (with respect to identifying either mild/moderate or severe CI) and specificity of 84%, by EEG network analysis. Significance: This study outlines a data-driven methodology for identifying candidate biomarkers of CI in CWEOE from network features. Following additional replication, the proposed method and its use of routinely acquired EEG forms an attractive proposition for supporting clinical assessment of CI.
Preventing murine transfusion‐related acute lung injury by expansion of CD4+CD25+FoxP3+ Tregs using IL‐2/anti‐IL‐2 complexes

Transfusion‐related acute lung injury (TRALI) is one of the most serious adverse events following transfusion, and there is no specific treatment in clinical practice. However, regulatory T cells (Tregs) have been suggested to play a potential role in the treatment of TRALI. This study investigated whether interleukin (IL)‐2 or IL‐2/anti‐IL‐2 complexes (IL‐2c), which are mediators of Treg expansion, can modulate the severity of antibody‐mediated TRALI in vivo.
Disease activity, treatment and long-term prognosis of adult juvenile idiopathic arthritis patients compared with rheumatoid arthritis patients

Abstract Objective: To evaluate the difference between adult juvenile idiopathic arthritis (JIA, starting at <16 years) and rheumatoid arthritis (RA). Methods: Data on 128 adult JIA patients were from the National Database of Rheumatic Diseases in Japan (NinJa), 2014, divided into 4 groups by period of disease onset (Group 1: 2000–2013, n = 32; Group 2: 1981–1999, n = 32; Group 3: 1966–1980, n = 31; Group 4: ∼1965, n = 33). Disease activity, treatment and long-term prognosis of adult JIA patients were compared with RA patients matched for sex- and disease duration in each era. Results: In Groups 1 and 2, adult JIA patients had significantly lower clinical disease activity indices (CDAI) (Group 1: adult JIA 1.5 [0.4–6.9]-vs-RA 5.3 [2.5–10.3], p = .001, Group 2: 2.6 [0.6–9.0]-vs-6.9 [3.5–11.0], p = .001, shown as median [quartile range], p-value, respectively), and had higher CDAI remission rates than RA patients (Group 1: 54.8%-vs-28.2%, p = .002, Group 2: 51.7%-vs-17.0%, p < .001). More adult JIA than RA patients in Group 1 used biologics (62.5%-vs-24.7%, p < .001). However, there were no adult JIA-vs-RA differences in joint destruction and physical function in any group. Conclusions: Adult rheumatologists must recognize that adult JIA patients are different from RA patients even when disease duration is the same.
Science Through Technology Enhanced Play: Designing to Support Reflection Through Play and Embodiment

We describe the design of the Science through Technology Enhanced Play (STEP) project. In STEP, we explore the potential for dramatic play, a form of activity that is familiar to early elementary students, in promoting meaningful reflection about scientific content. We report on the first round of design experiments conducted with 18 second-grade students who explored states of matter within the STEP environment. Pre-post analyses indicate that the majority of students learned the content and demonstrate how the design promotes distinct forms of reflection. In particular, it appears that students attended to the projected simulation at key moments in play and then reflected on the underlying rules of the content.
Usability aspects of medication-related decision support systems in the outpatient setting: A systematic literature review

In this study, we evaluated the usability aspects of medication-related clinical decision support systems in the outpatient setting. Articles published between 2000 and 2016 in Scopus, PubMed and EMBASE were searched and classified into three usability aspects: Effectiveness, Efficiency and Satisfaction. Using Van Welie et al.’s usability model, we categorized usability aspects in terms of usage indicators and means. Out of the 1999 articles, 24 articles met the selection criteria of which the main focus was on reducing inappropriate medication, prescription rate and prescription errors. Evidence could mainly be found for Effectiveness and showed high rates of positive results in reducing medication errors. To date, the effects of Efficiency and Satisfaction of clinical decision support systems regarding medication prescription remain understudied. Usability aspects such as memorability, learnability, adaptability, shortcuts and consistency require more attention. Studies are needed for better insight into the user model and to design a knowledge/task model for clinical decision support systems regarding medication prescription.
Caregivers’ resilience in mild and moderate Alzheimer's disease

Abstract Objectives: To investigate the resilience of caregivers of people with mild and moderate Alzheimer’s disease (PwAD) and the related sociodemographic and clinical characteristics. Methods: Cross-sectional assessment of dyads of PwAD and family caregivers (N = 106). Caregivers were assessed for resilience, depression, anxiety, hopelessness, quality of life, burden and cognition. PwAD were assessed for severity of dementia, cognition, neuropsychiatric symptoms, functionality, quality of life and awareness of disease. Results: Most of the caregivers (51.1%) reported emotional problems (symptoms of anxiety, stress and depression). In both mild (p < 0.05) and moderate (p < 0.05) PwAD groups, resilience was inversely related to self-reported emotional problems. There was not a significant difference between caregivers of mild and moderate PwAD resilience (p < 0.05). Upon analyzing the factors related to resilience, we found some differences between the groups of caregivers of mild and moderate PwAD. Neuropsychiatric symptoms of PwAD (p < 0.05) and caregiver’s depressive symptoms (p < 0.05) were related to resilience of caregivers of mild PwAD. In the moderate group, caregivers’ higher levels of quality of life (p < 0.05) and co-residing with PwAD (p < 0.05) were related to resilience. Conclusion: Caregivers’ resilience is driven by different factors according to disease severity. The findings suggest that resilience allows caregivers to manage and respond positively to stressful demands of care.
Market discipline and liquidity risk: Evidence from the interbank funds market

This paper identifies bank-specific-characteristics and market conditions that contribute to determine prices and demand for liquidity in the interbank market as wells as banks’ access to this market. Results indicate that riskier banks pay higher prices and borrow less liquidity, concurrent with the existence of market discipline. More capitalized and liquid banks tend to pay less for their funds and to have greater access to the interbank market. We find that banks pay higher prices and hoard liquidity when liquidity positions across them are more imbalanced and during a monetary policy tightening. Besides, small banks are found to suffer more as their credit risk and liquidity risk increase. We show that lending relationships benefit banks in hedging liquidity risk. We also document that central bank liquidity increments are associated with a downward pressure on interbank funds’ prices and augmented market activity. Overall, our results have implications for financial stability and for the transmission of the monetary policy as well.
Mixingcharacterization insidemicrodroplets engineeredonamicrocoalescer

We use a microdevice where microdroplets of reagents are generated and coalesce in a carrier continuous phase. The work focuses on the characterization of the mixing step inside the droplets, in the perspective to use them for chemical kinetic data acquisition. A dye and water are used, and an acid–base instantaneous chemical reaction is monitored thanks to a colored indicator. Acquisitions are done with a high-speed camera coupled to a microscope and a mixing parameter is calculated by image analysis. Different angles of bended channels and different ways of coalescence are compared. It is shown that the homogenization of the droplets can be reached in less than 10 ms after coalescence. This is achieved by forcing the droplets to coalesce in a “shifted” way, and later by adding 45 angle bends along the channel.
Bioethanol Production from Cotton Stalks or Corn Stover? A Comparative Study of Their Sustainability Performance

The production of second generation biofuels, ones produced from lignocellulosic materials, has not yet been developed in a full commercial scale. However, a considerable number of pilot and demonstration plants have been announced or set up in recent years with research activities taking place mainly in North America, Europe, and a few other countries, while commercial plants are about to start operation at the same time their environmental and economic performance are under examination. These performance issues are very sensitive on a variety of parameters such as feedstock material, production technology, logistics involved, etc. In this study, the sustainability performance of two alternative bioethanol production systems, namely, one using cotton stalks and a second using corn stover feedstock, are examined and compared using the analytic hierarchy process method. Life cycle impact assessment is used in order to evaluate each alternative’s environmental performance. For this purpose, a modern, powerf.
Dynamics and temporal changes in suspended sediment transport in northern Finland: transport of very fine particulate matter

1) Water Resources and Environmental Engineering Research Group, P.O. Box 4300, FI-90014, University of Oulu, Finland (*corresponding author’s e-mail: hannu.marttila@oulu.fi) 2) Department of Biological and Environmental Science, P.O. Box 35, FI-40014 University of Jyväskylä, Finland 3) Finnish Environment Institute, Freshwater Centre, Survontie 9 A, FI-40500 Jyväskylä, Finland 4) Department of Mathematics and Statistics, P.O. Box 35, FI-40014 University of Jyväskylä, Finland 5) Pöyry Finland Oy, Tutkijantie 2A, P.O. Box 20, FI-90571 Oulu, Finland
ON OPTIMAL GQL ESTIMATION APPROACH FOR LONGITUDINAL DYNAMIC BINARY MODEL: APPLICATION TO THE MATERNAL MORBIDITY DATA OF BANGLADESH

A longitudinal non-linear binary dynamic (NLBD) model which provides a full range for the longitudinal correlation parameter was attempted to analyze longitudinal morbidity data for determining the potential determinants of antenatal care (ANC) seeking behavior of pregnant women during their pregnancies. The regression and dependence parameters were estimated by optimal generalized quasilikelihood (OGQL) estimation approach. The estimate of dependence parameter was found to be significantly large. Age at marriage, economic status, husband's occupation, distance from health facility and numbers of previous pregnancies were found to have significant impact on the ANC seeking behavior DOI: http://dx.doi. org/10.3329/bjsr.v26i1-2.20227 Bangladesh J. Sci. Res. 26(1-2): 21-28, December-2013
State-Space Adaptation of Unsteady Lifting Line Theory: Twisting/Flapping Wings of Finite Span

In this paper, a low-order state-space adaptation of the unsteady lifting line model has been analytically derived for a wing of finite aspect ratio, suitable for use in real-time control of wake-dependent forces. Each discretization along the span has between 1–6 states to represent the local unsteady wake effects, rather than remembering the entire wake history which unnecessarily complicates controller design. Sinusoidal perturbations to each system degree of freedom are also avoided. Instead, a state-space model is fit to individual indicial functions for each blade element, allowing the downwash and lift distributions over the span to be arbitrary. The wake geometry is assumed to be quasi steady (no roll up) but with fully unsteady vorticity. The model supports time-varying surge (a nonlinear effect), dihedral, heave, sweep, and twist along the span. Cross-coupling terms are explicitly derived. This state-space model is then validated through comparison with an analytic solution for elliptic wings, a.
Computational Analysis of Magnetic Resonance Images of the Upper Airways: Algorithms and Applications

V CONTENTS VI LIST OF FIGURES VIII LIST OF TABLES IX NOMENCLATURE X INTRODUCTION 1 1.1. MOTIVATION 2 1.2. OBJECTIVES 2 1.3. REPORT ORGANIZATION 3 HUMAN UPPER AIRWAY ANATOMY 5 2.1. ANATOMY OF THE TONGUE 6 2.2. NEUROPHYSIOLOGICAL CONTROL OF THE TONGUE 12 2.3. SPEECH PRODUCTION, RESPIRATION AND DEGLUTITION 13 2.4. FINAL CONSIDERATIONS 16 MAGNETIC RESONANCE IMAGING IN THE CONTEXT OF UPPER AIRWAY STRUCTURAL COMPONENTS 19 3.
Modelspace Cooperative Document Information Extraction in Flexible Hierarchies

Business document indexing for ordered filing of documents is a crucial task for every company. Since this is a tedious error prone work, automatic or at least semi-automatic approaches have a high value. One approach for semi-automated indexing of business documents uses self-learning information extraction methods based on user feedback. While these methods require no management of complex indexing rules, learning by user feedback requires each user to first provide a number of correct extractions before getting appropriate automatic results. To eliminate this cold start problem we propose a cooperative approach to document information extraction involving dynamic hierarchies of extraction services. We provide strategies for making the decision when to contact another information extraction service within the hierarchy, methods to combine results from different sources, as well as aging and split strategies to reduce the size of cooperatively used indexes. An evaluation with a large number of real-world business documents shows the benefits of our approach.
Use of Discourse Markers by Iranian Teachers of English as a Foreign Language

Since discourse markers seem to be crucial to the organization of discourse, this study explores the rate of use of discourse markers (DMs) by Iranian teachers of English. For this the researcher chose three teachers who were teaching in the English institutes of Lahijan and Langerud for at least 5 years. They were considered very good users of English in terms of scores obtained in the IELTS exam before taking the job and again 1year before the current study. The talk of the teachers was recorded for three semesters. This equals to 126 hours of class recording. The teachers were teaching in elementary, intermediate, and advanced classes. After transcription of 126 hours of talk, the researcher found that two of the teachers who had the experience of living in English speaking countries were good users of discourse markers, but one who had no experience of such kind was a weak user of the DMs. The researcher found the evidence that years of living in an ESL setting had an influence on the use of DMs. The researcher believes that having such knowledge of functions and meanings of discourse markers by teachers can help learners of English to develop competence in this regard too. Further studies of this kind seem necessary to increase our knowledge concerning this issue.
Rapid, continuous streaking of tremor in Cascadia

Nonvolcanic tremor is a recently discovered weak seismic signal associated with slow slip on a fault plane and has potential to answer many questions about how faults move. Its spatiotemporal distribution, however, is complex and varies over different time scales, and the causal physical mechanisms remain unclear. Here we use a beam backprojection method to show rapid, continuous, slip‐parallel streaking of tremor over time scales of several minutes to an hour during the May 2008 episodic tremor and slip event in the Cascadia subduction zone. The streaks propagate across distances up to 65 km, primarily parallel to the slip direction of the subduction zone, both updip and downdip at velocities ranging from 30 to 200 km/h. We explore mainly two models that may explain such continuous tremor streaking. The first involves interaction of slowly migrating creep front with slip‐parallel linear structures on the fault. The second is pressure‐driven fluid flow through structurally controlled conduits on the fault. Both can be consistent with the observed propagation velocities and geometries, although the second one requires unlikely condition. In addition, we put this new observation in the context of the overall variability of tremor behavior observed over different time scales.
Hiv/Aids And Poverty In South Africa: A Bayesian Estimation Of Selection Models With Correlated Fixed-Effects

In this paper, we estimate the causal impact of human immunodeficiency virus/acquired immune deficiency syndrome (HIV/AIDS) on monetary poverty using a panel database from South Africa. We treat endogeneity and selection problems associated with HIV/AIDS by a selection model that includes correlated fixed effects both in the level and in the participation equations, which are estimated simultaneously via original Bayesian methods. We model the consequences of the illness on both labour income and income transfers, and disentangle between urban and rural households. While no significant impact of HIV/AIDS on labour income is found because of households' recomposition, we find a substantial fall in received transfers among rural population and a dramatic increase in chronic poverty.
Title : Beyond Prototypes : Drivers of Market Categorization in Functional Foods and Nanotechnology Year : 2015 Version : Post print

Rights: © 2015 Wiley-Blackwell. This is the post print version of the following article: Granqvist, Nina & Ritvala, Tiina. 2015. Beyond Prototypes: Drivers of Market Categorization in Functional Foods and Nanotechnology. Journal of Management Studies. Volume 53, Issue 2. 210-237. ISSN 0022-2380 (printed). DOI: 10.1111/joms.1216, which has been published in final form at http://onlinelibrary.wiley. com/doi/10.1111/joms.12164/full
TOWARD A UNITARY ACCOUNT OF DIVERSE SHI CONSTRUCTIONS IN MANDARIN CHINESE

The morpheme ＂shi＂ (the fourth tone) in Mandarin has four major uses: as a copula verb, a verum focus marker and an associate of argument/adjunct focus, and it is also involved in elliptical sentences. These uses have been well-observed in the literature, and many previous attempts have been made to provide a unitary theoretical characterization of these uses. In this paper, a revisit is paid to these uses of ＂shi＂ and it is argued that some of the latest unitary theoretical accounts of this morpheme are problematic. A novel unitary theoretical account of these uses is formulated from a parsing perspective in the framework of Dynamic Syntax, wherein sentences are viewed as left-to-right word-by-word monotonic processes of constructing propositions. It is proposed that ＂shi＂ always contributes a predicate of identity relation which combines with a corresponding formula of some logical type. Whether the presence of ＂shi＂ in a sentence gives rise to pragmatic effects or not depends on ＂shi＂ and the syntactic properties of the expression following ＂shi＂.
In vitro assessment of probiotic properties of lactic acid bacteria isolated from vaginas of healthy cows

The present study was conducted to isolate lactic acid bacteria (LAB) from vaginas of cows and evaluate their properties as probiotics. Forty-seven LAB strains were isolated from the vagina of cows using MRS agar and then their antibacterial effects were evaluated using Oxford cup method. Four strains (LAB1, LAB3, LAB5 and LAB9)demonstrating antibacterial activity were identified as Weissella confusa, Enterococcus hirae, Leuconostoc lactis and Ilyobacter polytropus, respectively.The results showed that the rank of hydrophobicity and adherence ability from largest to smallest was LAB9, LAB5, LAB3 and LAB1, respectively. Results of different combinations of the four LAB strains showed that LAB1+LAB3expressed higher adherence ability than other combinations (p£0.05); and LAB1+LAB9 had higher antibacterial activity than other combinations(p£0.05). Results of the present study provide essential information for developing probiotic product to prevent and treat reproductive tract infections of cows.
Monetary policy rules across OECD countries

This paper provides empirical evidence on cross-country monetary policy rules for the major OECD countries during the 1979Q2 to 1998Q4 period. The results point to a convergence of monetary policy practices towards a strict anti-inflation policy in the post-1987Q3 period. From 1979Q3 to 1987Q2, there is evidence of an accommodative monetary policy. Comparing the performance of alternative measures of inflation, PPI appears to have played an implicit role of target inflation rate in the latter period. Such a policy avoids unnecessary fluctuations in the nominal interest rate, which only reacts to disturbances that affect domestic variables.
Understanding Service Reusability

Reusability of software components is a key determinant of application development productivity and maintainability of applications. Reuse is regarded by many organizations as the top driver for the adoption of SOA. However the mechanism for achieving reusability of services is poorly understood at present and there is evidence that design of services for reuse is not a prime objectives when implementing SOA. The design of services is driven primarily by performance and scalability considerations, rather than any sound software engineering principles. In this paper we argue that excessive use of coarse-grained, document-centric messages results in poor reuse and undesirable interdependencies between services. We discuss the relationship between granularity of services, service reuse and service composability and describe how developers of Web Services applications can get a better understanding of the tradeoffs between performance, reuse, and maintainability of service-oriented applications.