Miracle-dz/UniFAR-FTUs huggingface dataset:
O perdão interpessoal em relação a variáveis psicossociais e demográficas

The Enright Forgiveness Inventory - EFI (Portuguese version) was used to verify relationships between forgiveness and degree of injury to the agents of hurt and also the degree of affect, behavior and judgment from victims towards their offenders. It was also checked whether culture, gender, age and religion affect the act of forgiving. Two hundred Brazilians and 394 Americans participated in the study. Findings were similar for both cultures. Forgiveness was negatively related to the degree of injury. People forgive family and friends at a higher degree than they forgive strangers or co-workers. Positive judgments received significantly higher scores than positive affect. No significant effect was found for forgiveness regarding gender, age or religion. Future studies should verify whether genuine forgiveness shows positive affect for offenders at a same degree as positive judgments or affect remains always lower than judgment for forgiving.
Elemental Profiles in Cycas micronesica Stems

Essential nutrients and metals have been quantified in stems of many tree species to understand the role of stems as storage and source organs. Little is known about stored stem resources of cycad tree species. Cycas micronesica tissue was collected from apical and basal axial regions of stems; and pith, vascular, and cortex tissues were separated into three radial regions. Leaves were also sampled to provide a comparison to stems. Minerals and metals were quantified in all tissues. Minerals and metals varied greatly among the six stem sections. Phosphorus varied more among the three radial sections than the other macronutrients, and zinc and nickel varied more than the other micronutrients. Stem carbon was less than and stem calcium was greater than expected, based on what is currently known tree stem concentrations in the literature. Elemental concentrations were generally greater than those previously reported for coniferous gymnosperm trees. Moreover, the stem concentrations were high in relation to leaf concentrations, when compared to published angiosperm and conifer data. The results indicated that the addition of more cycad species to the literature will improve our understanding of gymnosperm versus angiosperm stem nutrient relations, and that the non-woody cycad stem contains copious essential plant nutrients that can be mobilized and deployed to sinks when needed.
View‐Sharing Artifact Reduction With Retrospective Compressed Sensing Reconstruction in the Context of Contrast‐Enhanced Liver MRI for Hepatocellular Carcinoma (HCC) Screening

View‐sharing (VS) increases spatiotemporal resolution in dynamic contrast‐enhanced (DCE) MRI by sharing high‐frequency k‐space data across temporal phases. This temporal sharing results in respiratory motion within any phase to propagate artifacts across all shared phases. Compressed sensing (CS) eliminates the need for VS by recovering missing k‐space data from pseudorandom undersampling, reducing temporal blurring while maintaining spatial resolution.
A psychometric evaluation of the Multidimensional Social Competence Scale (MSCS) for young adults

The current study contributes to previous work on measuring the social phenotype in Autism Spectrum Disorder (ASD) by validating a multidimensional test of social competence developed for use with individuals with and without ASD. The “Multidimensional Social Competence Scale” (MSCS) was previously validated as a parent-rating scale with youth 11–18 years with ASD without intellectual disability and typically developing adolescents of comparable age. The current study presents a validation of a self-report version of the MSCS in a non-clinical young adult population (N = 1178, males = 360, females = 817, age range = 17–25 years). The MSCS consists of seven domains that represent social competence: social motivation, social inferencing, demonstrating empathic concern, social knowledge, verbal conversation skills, nonverbal sending skills, and emotion regulation. These domains are theorized to be indicative of the higher-order construct of social competence. A second higher-order theorization of the MSCS structure posits that 3 of these factors are indicative of social responsiveness, and the remaining 4 factors are indicative of social understanding and emotion regulation. Our findings indicated support for each of the theorized multidimensional factor structures. Reliability, optimal scoring, convergent and discriminant validity of the measure, as well as implications for future research are discussed.
Systemic Anti-Cancer Therapy in Synovial Sarcoma: A Systematic Review

Synovial sarcoma (SS) is an aggressive malignancy which accounts for approximately 5–10% of all soft-tissue sarcomas. SS has pathologic and genomic characteristics that define it as a distinct subtype of soft tissue sarcoma (STS). STS subtypes continue to be recognized as distinct entities with specific characteristics, including differential chemo-sensitivity. The objective of this study was to conduct a descriptive review of current data on survival outcomes of systemic anti-cancer therapy specific to SS. A systematic literature review was conducted, using a custom search strategy to search EMBASE, Medline and CENTRAL for clinical trials and observational studies reporting overall survival (OS), progression-free survival (PFS) and/or response for cohorts of at least 50 SS patients. We identified 28 studies meeting these criteria, 25 of which were retrospective studies. Only three prospective studies were identified. Survival reports varied widely between studies based on the population, in particular on the disease stage, and reporting was heterogeneous in terms of the time points reported on. For patients with localized disease, reports of five-year PFS ranged from 26% to 80.7% and five-year OS from 40% to 90.7%, whereas five-year OS for patients with metastatic disease was very low at around 10%; and in one case, 0% was reported. Only four of the included publications reported outcomes by type of systemic anti-cancer therapy received. Our study draws attention to the fact that additional prospective studies to better define the most appropriate treatment for SS in all stages and lines of therapy are still needed.
Next generation media monitoring: Global coverage of electronic nicotine delivery systems (electronic cigarettes) on Bing, Google and Twitter, 2013-2018

News media monitoring is an important scientific tool. By treating news reporters as data collectors and their reports as qualitative accounts of a fast changing public health landscape, researchers can glean many valuable insights. Yet, there have been surprisingly few innovations in public health media monitoring, with nearly all studies relying on labor-intensive content analyses limited to a small number of media reports. We propose to advance this subfield by using scalable machine learning. In potentially the largest contemporary public health media monitoring study to date, we systematically characterize global news reports surrounding electronic cigarettes or electronic nicotine delivery systems (ENDS) using natural language processing techniques. News reports including ENDS terms (e.g., “electronic cigarettes”) from over 100,000 sources (all sources archived on Google News or Bing News, as well as all news articles shared on Twitter) were monitored for 1 January 2013 through 31 July 2018. The geographic and subject (e.g., prevalence, bans, quitting, warnings, marketing, prices, age, flavor and industry) foci of news articles, their popularity among readers who share news on social media, and the sentiment behind news articles were assessed algorithmically. Globally there were 86,872 ENDS news reports with coverage increasing from 8 (standard deviation [SD] = 8) stories per day in 2013 to 75 (SD = 56) stories per day during 2018. The focus of ENDS news spanned 148 nations, with the plurality focusing on the United States (34% of all news). Potentially overlooked hotspots of ENDS media activity included China, Egypt, Russia, Ukraine, and Paraguay. The most common subject was warnings about ENDS (18%), followed by bans on using ENDS (13%) and ENDS prices (9%). Flavor and age restrictions were the least covered news subjects (~1% each). Among different subject foci, reports on quitting cigarettes using ENDS had the highest probability of scoring in the top three deciles of popularity rankings. Moreover, ENDS news on quitting and prices had a more positive sentiment on average than news with other subject foci. Public health leaders can use these trends to stay abreast of how ENDS are portrayed in the media, and potentially how the public perceives ENDS. Because our analytical strategies are updated in near real time, we aim to make media monitoring part of standard practice to support evidence-based tobacco control in the future.
Automatic Identification of Sewer Fault Types Using CCTV Footage

Water companies all over the world regularly perform inspections of their sewer networks. The data collected this way is then analysed by human technician which is time consuming and expensive. Previous work by the authors has developed methodology that can automatically detect faults in sewer pipes using standard CCTV footage. This paper presents a methodology to automatically identify types of detected faults aiming to further improve the efficiency and accuracy (i.e. consistency) of surveys. The methodology calculates a feature descriptor for individual frames of CCTV footage, before predicting the contents using a multi-class Random Forest classifier. Demonstrated on a comprehensive library of frames extracted from real-life CCTV footage of a UK water company, the methodology correctly identified the fault type in 71% of frames. Most common fault types were included in this experiment, covering a wide range of pipe sizes and materials, including vitrified clay, PVC and brick. Overall, this preliminary work shows promise for application in industry, proving an effective tool for analysing CCTV surveys.
Theaflavin and epigallocatechin‐3‐gallate synergistically induce apoptosis through inhibition of PI3K/Akt signaling upon depolymerizing microtubules in HeLa cells

Theaflavin (TF) and epigallocatechin‐3‐gallate (EGCG) both have been reported previously as microtubule depolymerizing agents that also have anticancer effects on various cancer cell lines and in animal models. Here, we have applied TF and EGCG in combination on HeLa cells to investigate if they can potentiate each other to improve their anticancer effect in lower doses and the underlying mechanism. We found that TF and EGCG acted synergistically, in lower doses, to inhibit the growth of HeLa cells. We found the combination of 50 µg/mL TF and 20 µg/mL EGCG to be the most effective combination with a combination index of 0.28. The same combination caused larger accumulation of cells in the G 2/M phase of the cell cycle, potent mitochondrial membrane potential loss, and synergistic augmentation of apoptosis. We have shown that synergistic activity might be due to stronger microtubule depolymerization by simultaneous binding of TF and EGCG at different sites on tubulin: TF binds at vinblastine binding site on tubulin, and EGCG binds near colchicines binding site on tubulin. A detailed mechanistic analysis revealed that stronger microtubule depolymerization caused effective downregulation of PI3K/Akt signaling and potently induced mitochondrial apoptotic signals, which ultimately resulted in the apoptotic death of HeLa cells in a synergistic manner.
Scientific Evolution of Clinical and Risk Assessment of Sexually Abusive Youth: A Comprehensive Review of Empirical Tools

Abstract Risk assessment of sexually abusive youth is a specialty, which ideally includes a clinical assessment (e.g., psychological evaluation) utilizing a validated risk assessment tool. This article reviews tools for assessing sexual improprieties and/or sexually abusive behaviors in youth: JSORRAT-II, J-SOAP-II, J-RAS, AIM2, and MEGA♪,1 and a clinical assessment tool, MIDSA. Untested, structured, clinical checklists with face validity, J-RAT-4 and PROFESOR, are included. The authors also highlight clinical dilemmas using “utility tools” (i.e., polygraph and plethysmograph) with sexually abusive youth. The comprehensive review sustains a twenty-first−century New Paradigm of inclusive ecologically based, developmentally and gender-sensitive assessment tools that definitively and accurately assess risk and protective factors of sexually abusive youth.
Application of Chaos Theory in Incomplete Randomized Financial Analysis

In the new economy, some tech companies have rapidly built market power and modernization led to the unpredictable bank-to-client relationship. Moreover, financial markets are confronted with big data and as a result, digitization and further introduction of mathematical techniques and new models were brought into the financial industry. Uncertainty has increased markedly in the macroeconomic risk, payment systems, capital accumulation and investment. But so far, timid attempts are made to elucidate the possibilities of the chaos theory application in finance. To verify a theoretical model whether or not is an accurate representation of an empirically observed phenomenon is one of the most challenging investigations in the scientific field. The following study explores the problem related to incomplete randomized financial analysis. The behavior of financial market relates to the circumstances that are both internal and external. Chaos mathematics is an acute methodology to be applied in the analysis of the randomness in financial markets instead of completely randomized design. The completely randomized design places the emphasis on which the factor effects are constant and assumes the observation from experiments to be statistically independent. However, this hypothesis is often not realistic and practical. The correlated impact should not be ignored. This article attempts to clarify some points related to the possibility of using chaos theory in finance.
Using forests to classify digital images

Riassunto: Questo lavoro illustra i risultati ottenuti utilizzando insiemi di classificatori ad albero, detti foreste, in un problema di classificazione automatica di immagini digitali. Il problema affrontato e quello della classificazione automatica di fotografie digitali come foto d’interno, d’esterno o primi piani. I risultati ottenuti mostrano che, rispetto all’uso di singoli alberi, l’utilizzo delle foreste produce un notevole miglioramento nell’accuratezza della classificazione, e anche che l’accuratezza puo’ essere ulteriormente migliorata introducendo nel processo di classificazione una regola di rigetto.
A Novel Hybrid Swarm Optimized Multilayer Neural Network for Spatial Prediction of Flash Floods in Tropical Areas Using Sentinel-1 SAR Imagery and Geospatial Data

Flash floods are widely recognized as one of the most devastating natural hazards in the world, therefore prediction of flash flood-prone areas is crucial for public safety and emergency management. This research proposes a new methodology for spatial prediction of flash floods based on Sentinel-1 SAR imagery and a new hybrid machine learning technique. The SAR imagery is used to detect flash flood inundation areas, whereas the new machine learning technique, which is a hybrid of the firefly algorithm (FA), Levenberg–Marquardt (LM) backpropagation, and an artificial neural network (named as FA-LM-ANN), was used to construct the prediction model. The Bac Ha Bao Yen (BHBY) area in the northwestern region of Vietnam was used as a case study. Accordingly, a Geographical Information System (GIS) database was constructed using 12 input variables (elevation, slope, aspect, curvature, topographic wetness index, stream power index, toposhade, stream density, rainfall, normalized difference vegetation index, soil type, and lithology) and subsequently the output of flood inundation areas was mapped. Using the database and FA-LM-ANN, the flash flood model was trained and verified. The model performance was validated via various performance metrics including the classification accuracy rate, the area under the curve, precision, and recall. Then, the flash flood model that produced the highest performance was compared with benchmarks, indicating that the combination of FA and LM backpropagation is proven to be very effective and the proposed FA-LM-ANN is a new and useful tool for predicting flash flood susceptibility.
Dosimetry Estimate and Initial Clinical Experience with 90Y-PSMA-617

Because of different physical properties, the β-emitters 177Lu and 90Y offer specific radiologic–biologic advantages in dedicated clinical situations. Our objective was to introduce 90Y-labeled prostate-specific membrane antigen (PSMA)–617 to clinical application, providing additional avenues for personalized medicine. Here, we present our dosimetry estimate for 90Y-PSMA-617, report first clinical experiences, and discuss the advantages and drawbacks of varying the β-emitter in PSMA-targeting radioligand therapy. Methods: To approximate radiation dosimetry, 4 patients with metastatic castration-resistant prostate cancer underwent serially performed imaging up to 1 wk after 177Lu-PSMA-617 therapy. Time–activity curves were extrapolated to the half-life of 90Y, and OLINDA was used to calculate the dosimetry estimate. In clinical practice, 11 patients with PSMA-positive lymph-nodal bulk disease were stratified to receive 90Y-PSMA-617 radioligand therapy (mean, 3.2 GBq; range, 2.8–3.7 GBq); afterward, safety lab tests, prostate-specific antigen (PSA) response, and clinical findings were thoroughly followed. Results: The projected dosimetry for 90Y-PSMA-617 estimated a mean kidney dose of 3.47 ± 1.40 Gy/GBq, red marrow dose of 0.11 ± 0.04 Gy/GBq, and salivary gland dose of 5.57 ± 1.34 Gy/GBq; randomly chosen metastases were approximated with 22.8 ± 16.10 Gy/GBq. The observed acute hematologic toxicity (5 cases of leukopenia and 2 of thrombocytopenia, all grade 1 or 2) and clinical side effects (2 cases of transient xerostomia and 1 of nausea, all grade 1 or 2), as well as PSA response (any PSA response, 7/11 patients; >50% PSA decline, 5/11 patients), were comparable to 177Lu-PSMA-617 literature data. Conclusion: A factor 3–4 lower treatment activity for 90Y-PSMA-617 translates into a comparable dosimetry estimate and clinical findings similar to those of 177Lu-PSMA-617. However, safety was demonstrated only for patients with oligometastatic disease. Further studies are needed to evaluate its potential in patients with more disseminated bone involvement or visceral metastasis.
Penggunaan alat peraga manipulatif untuk pembelajaran konsep pecahan bagi Guru Matematika Tingkat SMP

This paper is the result of the Community Partnership Program (PKM) activity by presenting the use of Acrylic Manipulative Aids (APMA) for learning fraction concepts for math teachers. The purpose of the activity is to maximize active learning activities in the classroom and use teaching aids in mathematics learning activities. The target is for junior high school teachers in Bulukumba District where 21 people are involved in the activity. The form of activities is training, while implementation information is fulfilled by providing worksheets and questionnaires as response sheets for activities. The results of the training activities carried out received a positive response. Not only is APMA considered feasible as a medium of learning or teaching aids, but it can also be used to help students overcome difficulties in learning the concept of fractions, fraction operations consisting of addition, subtraction, multiplication, and division. In addition, by convincing the teacher to respond that APMA can complete the explanations contained in mathematics textbooks. In other words, in addition to learning by using learning resources derived from books, APMA is also useful to supplement the provision of understanding to students in the classroom.
Safety and efficacy profiles of different commercial sodium hypochlorite/hypochlorous acid solutions (NaClO/HClO): antimicrobial efficacy, cytotoxic impact and physicochemical parameters in vitro

Background Sodium hypochlorite (NaClO, SHC)/hypochlorous acid (HClO, HCA) wound irrigation solutions have experienced a renaissance in the prevention and treatment of low-level wound infections. They are attributed with lower cytotoxicity and have therefore gained increasing attention in daily clinical practice. Objectives To determine the cytotoxicity and antimicrobial efficacy of six NaClO/HClO wound irrigation solutions. Methods For cytotoxicity evaluation (based on DIN EN 10993-5), human keratinocytes (HaCaT) and human skin fibroblasts (BJ) were used. Staphylococcus aureus and Pseudomonas aeruginosa were used for antimicrobial efficacy evaluation (based on DIN EN 13727). Solutions were evaluated after 1, 5 and 15 min of exposure. Additionally, physicochemical properties (pH and oxidation-reduction potential values) were investigated. Results Efficacy and cytotoxicity varied significantly between solutions. Generally, increasing antimicrobial activity was associated with decreasing cell viability. Furthermore, a concentration- and time-dependent impact on pathogens and cells was observed: cytotoxic and antimicrobial activity increased with rising NaClO/HClO solution concentrations and extended exposure times. Based on these in vitro evaluations, the following ranking (lowest to highest microbicidal effect and cytotoxic impact) was found: Microdacyn60® (SHC/HCA-M) < Granudacyn® (SHC/HCA-G) < Veriforte™ (SHC/HCA-V) < KerraSol™ (SHC-K) < Lavanox® (SHC-L) ≪ ActiMaris®forte (SHC/SM-A). Conclusions The presented results indicate that microbicidal effects are almost always associated with certain negative side effects on cell proliferation. Efficacy and biocompatibility of NaClO/HClO solutions depend on their specific formulation and physicochemical properties. The investigations also underline the necessity for exact product- and application-specific efficacy profiles.
Psychotherapeutic Yoga Demonstrates Immediate Positive Effects

Although various yoga practices (YBPs) have existed for centuries as a self-proclaimed system of healing (Khalsa, 2007; Saraswati, 2011), YBPs have only recently been increasingly integrated into Western models of healing and well-being. Clinical practices are increasingly incorporating elements of mindfulness in philosophies and treatments (e.g., Hayes, Srosahl, & Wilson, 1999; Linehan, 1993; Brach, 2003) and reporting that improved mindfulness leads to positive mental health outcomes (Kiken, Garland, Bluth, Palsson, & Gaylord, 2015). Research on effectiveness of YBPs has reported variable results (Jeter, Slutsky, Singh, & Khalsa, 2015; Büssing, Michalsen, Khalsa, Telles, & Sherman, 2012), but there is some evidence of reduced anxiety (Michalsen et al., 2005; Valoriani et al., 2014) and depression (Kinser, Bourguignon, Whaley, Hauenstein, & Taylor, 2013). The study described herein sought to more rigorously explore outcomes of psychological well-being immediately following a psychotherapeutic yoga class. Findings revealed that a single session of psychotherapeutic yoga decreased anxiety and increased subjective well-being, even after controlling for therapist variability, prior yoga experience, and client diagnosis. This is the first study to examine outcomes of an ongoing YBP in the naturalistic setting of an outpatient counseling center while rigorously controlling for confounding factors (e.g., therapist variability).