Miracle-dz/UniFAR-FTUs huggingface dataset:
Protein thiols as novel biomarkers in ecotoxicology: A case study of oxidative stress in Mytilus edulis sampled near a former industrial site in Cork Harbour, Ireland

Oxidative stress produces reactive oxygen species which can modify proteins and thiols of cysteines are especially susceptible. Mytilus edulis was sampled from three stations in Cork Harbour, Ireland and from an out-harbour control site in Bantry Bay, Ireland. A variety of traditional biomarkers were benchmarked against thiol oxidation. Lysosomal membrane stability diminished in haemocytes from the three Cork harbour sites, although a stronger effect was observed in two in-harbour stations of environmental concern (Douglas and Haulbowline Island). Catalase and glutathione transferase (GST) activities were decreased in digestive gland extracts of animals from in-harbour sites especially the in-harbour control (Ringaskiddy) showed lower GST than Bantry. Mussels collected at Haulbowline Island showed elevated lipid peroxidation (p
The microphysics of clouds over the Antarctic Peninsula - Part 1: Observations

Observations of clouds over the Antarctic Peninsula during summer 2010 and 2011 are presented here. The peninsula is up to 2500 m high and acts as a barrier to weather systems approaching from the Pacific sector of the Southern Ocean. Observations of the number of ice and liquid particles as well as the ice water content and liquid water content in the clouds from both sides of the peninsula and from both years were compared. In 2011 there were significantly more water drops and ice crystals, particularly in the east, where there were approximately twice the number of drops and ice crystals in 2011. Ice crystals observations as compared to ice nuclei param-eterizations suggest that secondary ice multiplication at temperatures around −5° C is important for ice crystal formation on both sides of the peninsula below 2000 m. Also, back trajectories have shown that in 2011 the air masses over the peninsula were more likely to have passed close to the surface over the sea ice in the Weddell Sea. This suggests that the sea-ice-covered Weddell Sea can act as a source of both cloud condensation nuclei and ice-nucleating particles.
ALMA reveals a chemically evolved submillimeter galaxy at z = 4.76

The chemical properties of high-z galaxies provide important information for constraining galaxy evolutionary scenarios. However, widely used metallicity diagnostics based on rest-frame optical emission lines are unusable for heavily dust-enshrouded galaxies (such as submillimeter galaxies; SMGs), especially at z > 3. Here we focus on the flux ratio of the far-infrared fine-structure emission lines [N ii]205 μ ma nd [Cii]158 μm to assess the metallicity of high-z SMGs. Through ALMA cycle 0 observations, we have detected the [N ii]205 μm emission in a strongly [C ii]-emitting SMG, LESS J033229.4‐275619 at z = 4.76. The velocityintegrated [N ii]/[C ii] flux ratio is 0.043 ± 0.008. This is the first measurement of the [N ii]/[C ii] flux ratio in high-z galaxies, and the inferred flux ratio is similar to the ratio observed in the nearby universe (∼0.02−0.07). The velocity-integrated flux ratio and photoionization models suggest that the metallicity in this SMG is consistent with solar, implying that the chemical evolution has progressed very rapidly in this system at z = 4.76. We also obtain a tight upper limit on the CO(12−11) transition, which translates into CO(12−11)/CO(2−1) < 3. 8( 3σ). This suggests that the molecular gas clouds in LESS J033229.4‐275619 are not significantly affected by the radiation field emitted by the AGN in this system.
Devising a method for the estimation and prediction of technical condition of ship complex systems

In the course of devising and examining a method for the estimation and prediction of technical condition of ship CTS, operated under conditions of unpredictable extreme and technogenic impacts, we received new theoretical and practical results. A place in the hierarchy and topology of the FIIS elements of ship CTS is defined based on the characteristics of the energy, material and information resources used by the systems in the devised method for the estimation and prediction of technical condition of CTS. The most vulnerable elements of FIIS of ship CTS are found with regard to their weight values in the systems, obtained by cognitive imitation and fuzzy simulation. The CTS elements, prone to failures, are determined by their advance detection by modeling the processes of decision making support in the search for reasons of failures. The strategy of restoring the FIIS elements of ship CTS with decision making support when searching for the reasons of their failures is based on the prediction of change in the probability of losing working ability and risk of failures of the elements. The obtained results improve reliability of ship CTS in the operation under conditions of extreme and technogenic impacts.
Sensitivity of alpine glacial change detection and mass balance to sampling and datum inconsistencies

Abstract. Glacial mass balance estimated through the geodetic method requires glacial surface coordinate observations from historical and contemporary sources. Contemporary observations and historical topographic maps are typically referenced to separate horizontal and vertical datums and observed with different sampling intervals. This research demonstrates the sensitivity of glacial change detection to the datum considerations and sampling schemes through case studies of Andrei, Bridge and Peyto glaciers in Western Canada. To simulate the procedure of observing the glacial surfaces, profile lines were sampled from Digital Elevation Model (DEMs) on contour intervals for historical data and horizontal intervals for contemporary data. Profile lines from the following scenarios were compared: (1) different horizontal and vertical sampling schemes; (2) the horizontal datum was correctly reconciled but the vertical datum was not; (3) the vertical datum was correctly reconciled but the horizontal datum was not; (4) both the horizontal and vertical datums were correctly reconciled; and (5) both the horizontal and vertical datums were incorrectly reconciled. Vertical errors of up to 6.9 m, 6.0 m and 5.0 m were observed due to sampling effects and vertical errors of 22.2 m, 9.9 m and 55.0 m were observed due to datum inconsistencies on Bridge, Andrei and Peyto glacier respectively. Horizontal datum inconsistencies manifested as erratic levels of growth or downwasting along the glacial surface profile and vertical datum errors manifested as a consistent vertical offset. Datum inconsistencies were identified to contribute errors of up to 257.2 × 106 m3 (or 87%) and 54.6 × 106 m3 (or 580%) of estimated volume change below and above the equilibrium line respectively on Peyto Glacier. The results of this study provide an estimate of typical errors due to sampling constraints or datum inconsistencies as well as guidance for identifying where these error sources have contaminated mass balance results.
Application of RNA interference in plants.

Gene silencing can occur either through repression of transcription, termed transcriptional gene silencing (TGS), or through mRNA degradation, termed post-transcriptional gene silencing (PTGS). TGS results in reduction of transcription whereas PTGS results in sequence specific mRNA degradation in cytoplasm without dramatic changes in transcription of corresponding gene in nucleus. Both TGS and PTGS are used to regulate endogenous genes. Interestingly, mechanisms of gene silencing also protect the organism's genome from transposons, viruses. In this paper, molecular aspects and mechanisms of gene silencing in plant were reviewed. Finally, its applications were discussed.
Tools and Processes for enhanced Product Customization

O fornecimento de um sistema personalizavel permite que clientes e parceiros expandam as funcionalidades do produto para abranger as suas necessidades e os seus objetivos especificos. Mas as alteracoes ou adicoes de funcionalidades ao sistema-base requerem um profundo conhecimento da sua estrutura e do seu funcionamento, assim como competencias tecnicas que garantam alteracoes totalmente funcionais. Com o intuito de minimizar as dificuldades inerentes ao processo de desenvolvimento e teste destas customizacoes, os fornecedores de software disponibilizam ferramentas e documentacao de suporte.O principal foco do presente trabalho consiste na analise de projetos de customizacao, suas ferramentas e documentacao de suporte ao desenvolvimento, para a resolucao ou minimizacao das dificuldades e problemas do processo de customizacao. Atraves da definicao de uma estrategia de suporte a customizacao que propoe a extraccao de conhecimento como forma de documentacao orientada pelos conceitos dos Collective Knowledge Systems. E uma ferramenta que aumenta a simplicidade e a fiabilidade do processo apresentando de uma forma intuitiva ao utilizador a analise do codigo produzida pelo compilador.O presente trabalho contempla ainda a implementacao dessa estrategia de suporte ao processo de customizacao do Manufacturing Execution System (MES) da Critical Manufacturing (CMF), com vista a validar a sua eficacia.O Critical Manufacturing MES e um sistema de informacao personalizavel que realiza a gestao das operacoes em ambientes avancados de fabricacao garantindo um elevado desempenho e competitividade. A CMF garante a personalizacao do sistema para corresponder aos requisitos dos clientes e parceiros, mas a complexidade inerente a oferta de um sistema completo e competitivo implica uma estrategia de apoio a customizacao que garanta um processo simples, rapido e fiavel.Os resultados esperados para o presente trabalho, e consequentes da definicao de uma estrategia de apoio a customizacao de software sao: (1) uma ferramenta e documentacao de apoio que orientem os clientes e parceiros no seu processo de customizacao e (2), um aumento da confianca e eficiencia dos clientes e parceiros no desenvolvimento das suas personalizacoes atraves de um processo mais rapido e fiavel. A estrategia de apoio a customizacao definida procura ser a mais abrangente e generica possivel de forma a facilitar a sua adocao por outras entidades.
Competition, Total Quality Management Practices, and Performance: Evidence from Upscale Hotels

Hotels operate in a highly competitive market and therefore place a strong emphasis on quality management in order to gain/maintain competitiveness. This research examined the relationship between total quality management (tQM), market competition, and hotel departmental financial and nonfinancial performance. The data were collected from a sample of Australian and Indian hotels using a self-administered postal survey. the results suggested that while tQM and market competition had a direct interactive effect on hotel departmental nonfinancial performance, the effect on the financial performance was indirect. It was also suggested that those hotels subscribing to tQM philosophy were more likely to thrive on competition.
Propagator Method using PARAFAC Model for Two Dimensional Source Localization

In this paper, we addressed the problem of estimating the two-dimensional (2D) Direction of Arrival (DOA) elevation and azimuth angles for multiple sources. The proposed method employs Propagator Method (PM) in conjunction with parallel factor (PARAFAC) model using a new antenna array configuration. The proposed method overcomes two main drawbacks in the existing 2D DOA schemes: use of high computation eigenvalue decomposition (EVD) or singular value decomposition (SVD), and complex pair-matching methods for elevation and azimuth angles in case of multiple sources. Therefore, significant reduction in computational load and complexity is achieved. Computer simulations demonstrate the effectiveness of the proposed method.
Differences in Coping with Stressful Situations Between Tanzanian and Emirati University Students

This study was an attempt to examine and identify the coping dimensions of Tanzanian and UAE university students. A sample of 233 students was randomly selected from each of the two countries and the Coping Inventory for Stressful Situations (CISS) was used to assess their coping. Principal component analysis with varimax rotation was used to identify the coping dimensions of the two groups. Results showed significant variations in coping within and between the two samples. In addition, considerable differences between the two samples were found in relation to age, gender, and marital status. The results were further discussed in relation to previous findings, limitations were highlighted and future research considerations were recommended.
MCAST: Mobility-aware Channel-Availability based Channel Selection Technique

A key issue in cognitive radio networks is the design of a channel selection technique that guarantees to utilize the highest available channel in presence of the dynamic activity of primary users. Usually, the channel selection techniques that operate in this kind of network are based on the channelavailability probability. In the static primary user’s scenario, this probability can be a priori known or simply estimated from the channel occupancy history. However, in the mobile primary user’s scenario, this probability dynamically varies in time due to the changes of the primary user’s position. In order to exploit the dynamic variation of the channel availability, in this paper we design a novel Mobility-aware Channel-Availability based channel Selection Technique (MCAST) that ensures to select the channel with the highest channel availability probability in a given temporal interval. The simulation results highlight the benefits of the proposed technique in presence of primary user’s mobility. Moreover, we evaluate the effectiveness of MCAST in a scenario of practical interest by adopting this technique in a recently proposed routing metric designed for this network.
Exchange rate, marginal q and investment behaviour of small and medium-sized enterprises in Japan: time series evidence of manufacturing industries

ABSTRACT In this article, we investigate Granger’s causality among the exchange rate, Tobin’s marginal q and investment-capital ratio with quarterly data on firms categorized as small and medium-sized enterprises (SMEs) in Japan. We utilize the data of the following industries: chemical, iron and steel, production machinery, electric machinery and equipment, automobile and accessories and all manufacturing. The empirical results we obtain show that the null hypotheses of no Granger’s causality from the exchange rate to other variables, investment and marginal q, are accepted in all industries. The reason is the lower percentage of export by SMEs. Thus, it is considered that the effects of Abenomics on SMEs are limited, and that other kinds of reflation measures for SMEs are needed.
Radiation-Induced Cerebral Micro bleeds

A 29 year-old Thai female presented with a right-sided headache for 3 days prior to hospital admission. The patient complained of severe pain and upon examination, pain was found to be localized only on the right parietal area. Initially diagnosed as a migraine headache, the pain gradually improved with simple analgesics. She had neither history of head trauma, hypertension, diabetes, psychiatric problems, nor family history of Alzheimer’s disease. Seven years earlier at the age of 22 years, the patient presented with progressive headaches with nausea and vomiting followed by generalized tonic clonic seizures. The neurological examination at that time showed bilateral papilledema. Initial computed tomography (CT) scan (Figure 1) of the brain revealed a pineal region tumor with obstructive hydrocephalus. However, magnetic resonance imaging (MRI) of the brain was not performed at the initial diagnosis. Right occipital transtentorial craniectomy with near total tumor removal and ventriculo peritoneal shunt placement were performed. The pathological finding of the tumor was reported to be pineal parenchymal tumor grade III/IV based on the currently proposed system or pineal parenchymal tumor of intermediate differentiation (gr III or IV) according to WHO classification[1,2]. She received 30 Fractions of whole brain irradiation with 6 cycles of chemotherapy (cyclophosphamide and vincristine). The radiation dose ranged from 42 to 90 cGy per dose of each radiation site (total dose 36 Gy of whole brain irradiation with booster at tumor base up to 54 Gy). She received her first MRI 5 months after the last dose of radiation which showed only a few cerebral micro bleeds (CMBs) in the subcortical white matter of the left cerebral hemisphere. Magnetic resonance angiography (MRA) of the brain was normal and there was no evidence of cerebral infarction. Serial MRI of the brain was performed at 5 years after the cranial radiation and showed a markedly increase in number of CMBs (Figure 2)
DETERMINANTS OF QUALITY OF LIFE IN ELDERLY

Cieľ: Posudiť vplyv vybraných demografických (vek, pohlavie), socialno-ekonomických (rodinný stav, vzdelanie, prijem) a zdravotných faktorov (funkcný stav, uzkosť, depresia) na kvalitu života (QOL) seniorov v kosickom regione. Dizajn: Prierezova studia. Metodika: QOL bola posudena dotaznikom WHOQOL-BREF a WHOQOL-OLD, funkcný stav bol hodnotený Barthelovej testom aktivit denneho života (ADLs), uzkosť Beckovým dotaznikom uzkosti a depresia Zungovým seba-hodnotiacim dotaznikom depresie. Vzťahy medzi premennými boli posudene Pearsonovým korelacným koeficientom, linearna regresna analýza služila na vyhodnotenie prediktorov QOL. Výsledky: Vo vzorke stodva seniorov bola zistena najlepsia QOL v domene socialnych vzťahov, smrť a umieranie a blizke vzťahy, najhorsia QOL v domene fyzicke zdravie, socialne zapojenie a naplnenie. QOL bola u seniorov redukovana najma depresiou, polymorbiditou a životom bez partnera. Pozitivny vplyv na vacsinu domen QOL malo udržiavanie nezavislosti v ADLs. Zaver: Výsledky indikuju potrebu vytvarania priležitosti pre utvaranie a udržiavanie socialnych kontaktov, realizaciu roznych aktivit voľneho casu, zapajanie seniorov do roznych programov ci dobrovoľnickych aktivit. Pre zlepsenie kvality života seniorov je veľmi doležitý skrining a liecba depresie a uzkosti, ako aj udržiavanie a zlepsovanie sebestacnosti v ADLs.
Ergonomic modelling parameters and the influence of ergonomics on planning workplaces

Modern economic research divides all economics into structural levels: megaeconomics, macroeconomics, meso-economics, micro-economics, and nano-economics. From the point of such traditional divisions, the research is topical in the primary economic structure of society nano-economics and thanks to this work operations can be subdivided into workplaces in the form of transformation processes. The aim of the research is to develop ergonomic modelling parameters and to discover the influence of ergonomics on the planning of workplaces based on a case study. The research involved a study of workplace ergonomic planning methods and principles. Solutions for a series of problems which are related to the improvement of workplace ergonomics may be discovered in the following ways: improving work organisation in every workplace by using work process-related micro-elemental methods and a determination of work expenditure, the levels of physical strenuousness involved in the work, the complexity of the work, and the social importance of the workplace. These parameters will allow the workplace quantity characteristics to be discovered, such as in terms of a generalised parameter which conforms to the requirements which describe a workplace, and in terms of operational management via the condition of workplaces and the salary systems being utilised. The research provides a case study in which ergonomic modelling parameters are developed and concrete workplace interventions are introduced.
Sex-specific differences in f0 and vowel space

It has been suggested that the larger area of the average female acoustic vowel space is a consequence of compensating for poorer harmonic sampling of the spectral envelope resulting from a higher f0. This predicts that there should be variation in vowel space size within any group of males or females representing sufficient interindividual range of average f0. Inspired by this, the present paper examines whether there is a correlation between a speaker’s f0 and the size of the speaker’s F2×F1 vowel space. A highly significant correlation between f0 and vowel space size is found in the female group of a sample of 27 German students. However, no such correlation is found between f0 and the Euclidean distance between same speaker tokens of /e:/ and /a:/.
Iolite: Freeware for the visualisation and processing of mass spectrometric data

Iolite is a non-commercial software package developed to aid in the processing of inorganic mass spectrometric data, with a strong emphasis on visualisation versus time of acquisition. The goal of the software is to provide a powerful framework for data processing and interpretation, while giving users the ability to implement their own data reduction protocols. It is intended to be highly interactive, providing the user with a complete overview of the data at all stages of processing, and allowing the freedom to change parameters and reprocess data at any point. The program presents a variety of windows for the selection and viewing of data versus time, as well as features for the generation of X-Y plots, summary reports and export of data. In addition, it is capable of generating X-Y images from laser ablation rasters, and combining information from up to four separate elemental concentrations (intensities of red, green and blue, and the z-axis) in a false-colour three-dimensional image. By virtue of its underlying computing environment—Igor Pro—Iolite is capable of processing very large datasets (i.e., millions of timeslices) rapidly, and is thus ideal for the interrogation of multi-hour sessions of laser ablation data that can not be easily manipulated in conventional spreadsheet applications, for example. It is also well suited to multi-day sessions of solution-mode inductively-coupled plasma mass spectrometer (ICPMS) or thermal ionisation mass spectrometer (TIMS) data. A strong emphasis is placed on the interpolation of parameters that vary with time by a variety of user selectable methods including smoothed cubic splines. Data are processed on a timeslice-by-timeslice basis, allowing outlier rejection and calculation of statistics to be employed directly on calculated results. This approach can reduce the risk of processing biases associated with the manipulation of integrated datasets, while also allowing the implementation of more complex data reduction methods.
Exploring Cross-Group Discrimination : Measuring the Dimensions of lnferiorizationl

We describe a theoretical framework that identifies similar themes across the reported experiences o f historically stigmatized groups. lnferiorization i s a function o f the contluence o f stigma. context. and associated cultural myths. A self-report measure of inferiorization was applied to college-student samples of African Americans, White women. gay men and lesbians. people with disabilities, and, as a control. a White male comparison group (total N = 263). Stigmatizable people tended to report more frequent inferioriring events than generally nonstigmatizable people. Debiations from this pattern were explained by the contextual and stigma-related specificity o f inferiorization and the presence or absence o f associated cultural myths. Inferiorization describes a general social process that remains sensitive to the experiences o f specific groups and to the contemtal nature o f stigmatization.