Miracle-dz/UniFAR-FTUs huggingface dataset:
A Narrowband Corner Slot Patch Antenna for 2.4 GHz Wireless Radio Communications

AbstractA narrowband corner slot patch antenna has been designed for industrial, scientific, and medical radio band (ISM band) for short distance radio communication. These antennas are analyzed and are optimized using Ansoft High-Frequency Structure Simulator (HFSS). The objective is to shrink the size of the radiating patch element without compromising antenna performance. The proposed design is investigated under various parametric analyses and are compared. The overall size of the antenna is reduced by 32.8% when compared with traditional patch antenna available in the market. This can be achieved by introducing four slots inclined at 45 in the radiating patch. The antenna provides a bandwidth of 25% in ISM band (|S11|≤10dB) between 2.37 GHz to 2.43 GHz. In addition, maximum Voltage Standing Wave Ratio (VSWR) value near to 1.0 and gain of 7.5 dB is achieved. Finally, good agreement has been obtained for using this proposed design for short distance radio communications. Keyword Patch antenna, ISM band, Return loss, Standing wave ratio.
Assembly of a nucleoprotein complex required for DNA packaging by bacteriophage lambda.

A critical step in the assembly of bacteriophage lambda is the excision of a single genome from a concatemeric DNA precursor and insertion of genomic DNA into an empty viral capsid. DNA packaging is mediated by the lambda proteins gpNu1 and gpA, which form an enzyme complex known as terminase. Initiation of the packaging process requires assembly of the terminase subunits onto cos, the lambda DNA packaging sequence, and nicking of the duplex, thus forming the 12-base-pair "sticky" ends of the mature genome. We have utilized gel-retardation techniques to examine the interaction of gpNu1, gpA, and terminase holoenzyme with DNA. Our data demonstrate that gpNu1 interacts specifically with cos-containing DNA, forming three gel-retarded complexes. Similarly, the larger gpA subunit binds to DNA, forming two complexes; however, this subunit forms similar complexes with DNA substrates of random sequence. All of the nucleoprotein complexes examined are disrupted by elevated concentrations of NaCl and we suggest that altered DNA binding is responsible for the extreme salt sensitivity of the endonuclease activity of the enzyme [Tomka, M. A. , & Catalano, C. E. (1993) J. Biol. Chem. 268, 3056-3065]. DNA binding by each subunit is strongly affected by the presence of the other, with 10- and 3-fold increases in the affinity of gpNu1 and gpA, respectively, for DNA. Moreover, our data suggest that the terminase subunits interact in solution prior to DNA binding. Finally, we provide evidence that complex I, the first stable intermediate in the packaging pathway, is composed of the mature left genome end bound to the terminase subunits and demonstrate that dissociation of the complex is quite slow (t1/2 > 8 h). The significance of these data with respect to terminase-mediated genome packaging is discussed.
Design & Simulation of Switched-Beam Antenna using Butler Matrix Feed Network

Thispaper concentrates on development of Switched beam smart antenna system for 2.45GHz ISM band. A smart antenna system hasthe ability to direct the beam in desired direction thereby reducing the problem of multipath fading, delay, interference. Basically there are two types of smart antenna systems; one is Switched beam system and another Adaptive array system. This paper presents optimum designof a switched beam smart antenna using 4x4 planar Butler matrix array. The beamforming network is formed using micro strip antenna and buttler matrix (hybrid couplers, cross-coupler, phase shifter). All the individual components of buttler matrix as well as the microstrip patch antenna is designed and simulated. Finally thearchitecture of beamforming network simulated using HFSS softwareand made analysis of coupling effect between different fundamental elements of network. Keywords—Butlermatrix, microstrip antenna, beam forming network.
10 Therapeutic Strategies : Pulmonary Arterial Hypertension

CLINICAL PUBLISHING Pulmonary arterial hypertension (PAH) is a rare condition; yet this very rarity can be a disadvantage when it comes to treatment, making PAH di÷cult to diagnose, resulting in suboptimal patient care. Furthermore, the global burden of PAH remains poorly understood and largely underestimated, as PAH commonly presents as a comorbidity with such conditions as systemic sclerosis, COPD, idiopathic pulmonary fibrosis and left-heart dysfunction. However, in recent years there has been significant investment in developing new therapies for PAH, and treatment for this previously neglected disease is set to enter a new era. This new work draws on the recent published literature and clinical trials to review the latest developments in our understanding of the disease, new advances in therapy and current opinion on best practice approaches to management. Internationally-recognised authorities on PAH provide expert analysis of these advances and critical commentary on the data presented to help explain the implications of these findings for future clinical practice.
Use of Compliant Hinges to Tailor Flight Dynamics of Unmanned Aircraft

The nexus of advanced manufacturing methods, computer-aided design tools, and modern structural-analysis software has enabled the design and fabrication of structurally complex wing structures with unique features. This is particularly true for small unmanned aircraft, in which discrete structural hinges can easily be integrated into the overall vehicle design. This paper examines the use of discrete structural hinges for tailoring the low-frequency flight dynamics of the vehicle. For sufficiently soft discrete structural hinges, substantial coupling between flexible and rigid modes occurs, leading to the potential to modify the flight dynamic behavior through structural flexibility. Using a multibody flight dynamics simulation tool with a nonlinear lifting-line aerodynamic representation, different structural-hinge elastic properties, orientation, and location on the aircraft are examined. The results for a small unmanned aircraft indicate that flexibility mostly affects the longitudinal modes and associ.
Draft Genome Sequence of the Sponge-Associated Strain Bacillus atrophaeus C89, a Potential Producer of Marine Drugs

ABSTRACT Bacillus atrophaeus C89, isolated from the marine sponge Dysidea avara, is a potential producer of bioactive compounds, such as neobacillamide A and bacillamide C. Here, we present a 4.2-Mb assembly of its genome. The nonribosomal peptide synthetases (NRPSs) make it possible to produce the bioactive compounds.
Imaging in Axial Spondyloarthritis.

BACKGROUND Axial spondyloarthritis (axSpA) covers the stage of non-radiographic axial spondyloarthritis (nr-axSpA) and classic ankylosing spondylitis. The pathognomonic findings of axSpA are mainly inflammatory and osteoproliferative changes in the sacroiliac joints (SIJ) and the spine. Various imaging techniques are being used in daily practice for assessment of disease-specific changes, such as periarticular bone marrow edema, erosions, sclerosis, fat metaplasia and ankylosis in the SIJ or spondylitis, spondylodiscitis, facet joint involvement, or syndesmophytes in the spine of patients with axSpA. Conventional radiographs are still considered the gold standard for assessment of structural changes, while the method of for detection of inflammatory changes is magnetic resonance imaging (MRI). A result for an MRI in the SIJ is considered positive for axSpA when more than one lesion is present on one MRI slice, If there is one lesion only, this should be present on at least two consecutive slices. For the spine, inflammatory lesions should preferably be located in the corner of the vertebral bodies, while occurrence of spondylitis in three or more vertebral corners is considered highly suggestive of axSpA. This review gives a detailed overview about the benefits and limitations of all available imaging techniques in patients with axSpA, explains the usage of imaging techniques in the context of diagnosis and differential diagnosis of the disease, and reports on the potential future trends in the area of imaging of the axial skeleton in patients who are suspicious for this diagnosis.
Featured Collection Introduction: Water for Megacities — Challenges and Solutions

The Earth has entered into Anthropocene, a new epoch dominated by people. The world’s urban population has grown more than four times during the past 60 years to 3.9 billion. Today, more people are living in the cities than in the countryside in most nations. Cities are growing bigger and faster than ever before (United Nations, 2014). Cities that have a population >10 million are commonly considered as megacities as defined by UN-HABITAT (Li et al., 2015b). Globally, there are about 28 megacities with approximately 13% of the world’s urban population (United Nations, 2014). Most of these megacities are found in Asia. By 2030 the world is projected to have 41 megacities with cities in Africa and Asia growing the fastest (United Nations, 2014). Megacities face many emerging challenges, from economic development and social stability to environmental changes in the 21st Century. Obviously, many of the water resource challenges in megacities are rooted in the rapid rise in competing water demands by people for multiple uses. Water problems arise when water demand cannot be met by water supply due to either natural (e.g., surface or groundwater exhaustion), socioeconomic (e.g., financial and governance), water quality, or environmental constraints. Meeting rapidly growing water demand in megacities often means sacrificing the environment such as water quality degradation, ecosystem damage, and/or unsustainable water use such as groundwater depletion and salt water intrusion. Competing water use by irrigated agriculture, thermoelectric power generation, and industrial and residential water use are common causes of water shortages for megacities, especially in arid or semiarid regions or during extreme drought years. Water pollution alone from megacities can turn a “water rich” city into a “water poor” one as demonstrated by megacities in many developing countries. Climate change affects water availability everywhere, but megacities are most vulnerable simply because of the large water demand by people (Li et al., 2015a, b). Growing extreme weather events (e.g., hurricane, droughts, and floods) associated with climate change and variability pose some of the biggest challenges to water supply infrastructures in megacities. It is
A Joint TOA/AOA Constrained Minimization Method for Locating Wireless devices in Non-Line-of-Sight Environment

Non-line-of-sight (NLOS) propagation degrades the performance of wireless location systems. Thus, developing algorithms that are robust to NLOS is of great importance. This paper introduces a new location technique that utilizes time of arrival (TOA) and angle of arrival (AOA) measurements. In the proposed method, we assume the signal from the mobile station reaches each base station via one dominant scatterer. By including the scatterer's coordinates as unknowns in a TOA/AOA-based cost function and imposing some equality and inequality constrains, the location of the mobile station (MS) is shown to significantly improve. The performance of the proposed algorithm is assessed and compared with that of existing algorithms through extensive simulations.
A HW/SW Co-Verification Technique for Field Programmable Gate Array (FPGA) Test

Field programmable gate arrays (FPGAs) have wide and extensive applications in many areas. Due to programmable feature of FPGAs, faults of FPGAs can be easily tolerated if fault sites can be located. A hardware/software (HW/SW) co- verification technique for FPGA test is proposed and presented in the paper. Taking advantage of flexibility and observability of software in conjunction with high-speed simulation of hardware, this technique is capable of testing each input/output block (IOB) and configurable logic block (CLB) of FPGA automatically, exhaustively and repeatedly. Fault cells of FPGA can be positioned automatically by the proposed approach. As a result, test efficiency and reliability can be enhanced without manual work.
FLIPDock: Docking flexible ligands into flexible receptors

Conformational changes of biological macromolecules when binding with ligands have long been observed and remain a challenge for automated docking methods. Here we present a novel protein–ligand docking software called FLIPDock (Flexible LIgand–Protein Docking) allowing the automated docking of flexible ligand molecules into active sites of flexible receptor molecules. In FLIPDock, conformational spaces of molecules are encoded using a data structure that we have developed recently called the Flexibility Tree (FT). While the FT can represent fully flexible ligands, it was initially designed as a hierarchical and multiresolution data structure for the selective encoding of conformational subspaces of large biological macromolecules. These conformational subspaces can be built to span a range of conformations important for the biological activity of a protein. A variety of motions can be combined, ranging from domains moving as rigid bodies or backbone atoms undergoing normal mode‐based deformations, to side chains assuming rotameric conformations. In addition, these conformational subspaces are parameterized by a small number of variables which can be searched during the docking process, thus effectively modeling the conformational changes in a flexible receptor. FLIPDock searches the variables using genetic algorithm‐based search techniques and evaluates putative docking complexes with a scoring function based on the AutoDock3.05 force‐field.
Variable‐rate selective excitation for rapid MRI sequences

Balanced steady‐state free precession (SSFP) imaging sequences require short repetition times (TRs) to avoid off‐resonance artifacts. The use of slab‐selective excitations is common, as this can improve imaging speed by limiting the field of view (FOV). However, the necessarily short‐duration excitations have poor slab profiles. This results in unusable slices at the slab edge due to significant flip‐angle variations or aliasing in the slab direction. Variable‐rate selective excitation (VERSE) is a technique by which a time‐varying gradient waveform is combined with a modified RF waveform to provide the same excitation profile with different RF power and duration characteristics. With the use of VERSE, it is possible to design short‐duration pulses with dramatically improved slab profiles. These pulses achieve high flip angles with only minor off‐resonance sensitivity, while meeting SAR limits at 1.5 T. The improved slab profiles will enable more rapid 3D imaging of limited volumes, with more consistent image contrast across the excited slab. Magn Reson Med 52:590–597, 2004. © 2004 Wiley‐Liss, Inc.
Twitch relaxation of the cat soleus muscle at different lengths and temperatures

We recorded isometric and isotonic twitches, in situ, from the cat soleus at various muscle lengths and temperatures. At a given temperature the duration of isometric twitches increased approximately 60% for each 10% increase in muscle length, which was primarily owing to decreases in the rate of relaxation. For the relaxation of isometric twitches recorded at different muscle lengths, the equivalent activation energies determined were the same (13.2 ± 0.3 kcal/M). The duration of isotonic twitch contractions increased only 20% for each 10% increase in muscle length. Even a small amount of shortening (3%) diminished the dependence of twitch duration on muscle length. In this case, twitch duration increased approximately 30% for every 10% increase in muscle length. Hence, even small changes in internal and/or external compliance (eg, changes in the tendon‐fiber continuity) can greatly influence twitch duration. Our findings are consistent with the hypotheses that in the cat soleus, Ca2+ sequestration is primarily governed by a single energy dependent process and that the Ca2+ sensitivity of the contractile apparatus increases with increasing sarcomere length.
Alternative control methods for exploiting subsidiary knowledge within an MNE: quantity versus quality

Purpose – The aim of this paper is to expose the power of informal control mechanisms over explicit knowledge transfer through information communication technology (ICT) systems in subsidiaries of a multinational enterprise (MNE). Design/methodology/approach – The research used a case study approach consistent with the purpose of exploring control/knowledge transfer relationships. Semi-structured interviews were undertaken with managers across 19 sites in an MNE. Analysed data were thematically organised into two case studies for comparison. Findings – The results show that when control is exerted from bottom-up, knowledge transfer barriers are overcome, quality of outcomes is increased and new and incremental knowledge innovation is more likely to become organisational. Practical implications – The findings signal a caution for managers to assess the suitability of control type on knowledge transfer incentives to leverage quality knowledge outcomes. By using informal methods, subsidiary managers’ local a.
Digital Inclusiveness--Longitudinal Study of Internet Adoption by Older Adults

In order to build a digital inclusive society, both government and nongovernment organizations in countries such as China, Japan, Korea, Singapore, Taiwan, the United Kingdom, and the United States have been offering training programs to the general public and establishing communitywide public access computer facilities in recent years. However, offering training programs and enabling access to facilities are not sufficient on their own if, due to other reasons, the socially disadvantaged groups do not choose to make use of the facilities. As an exploratory investigation, this study focuses on the voluntary adoption of these facilities (typified by the Internet) by one such disadvantaged group--older adults. In particular, this study investigates the role of Internet self-efficacy and outcome expectations in older adults' usage of the Internet through a three-part longitudinal study, involving almost 1,000 participants. A theoretical model based on social cognitive theory was developed and empirically tested through both surveys and lab experiments. Behavioral modeling training courses were offered to adults age 55 or older in the study over a one-year period. Questionnaire surveys and cognitive knowledge assessments were conducted. In general, the findings in the longitudinal study (including three repeated measures) validated the affects of Internet self-efficacy and outcome expectations on usage intention, and the important roles of support and encouragement in the formation of self-efficacy and outcome expectations. Limitations and implications are discussed.
Borderline personality disorder and impulsive sexual behavior.

Patients with borderline personality disorder provide an ideal sample for a study of impulsive sexual behavior and factors related to it in psychiatrically ill women. Even though impulsive sexual behavior is one of the DSM-III-R criteria for borderline personality disorder, not all patients with the disorder manifest such behavior. While controlling for diagnosis, we identified factors related to sexual impulsivity of these patients. Our results suggest that impulsive sexual behavior is common in some women with borderline personality disorder. Forty-six percent of the women in our sample reported that they had impulsively entered into sexual relationships with partners they did not know well. Al though many axis I conditions that could contribute to impaired judgment were present, only alcohol abuse correlated with sexual impulsivity. Patients with impulsive sexual behavior were more likely to receive a comorbid axis II diagnosis of histrionic personality disorder, were more likely to have general proble.
IEEE TRANSACTIONS ON PATTERN ANALYSIS AND MACHINE INTELLIGENCE 4 HLV 2 ConvD 2 ConvD 1 ConvC 1 ConvC 1 ConvC 2 ConvC 2 max pooling ConvD 2 ConvD 1 HLV 1 shared hidden layer HLS HLV 1 HLV

We present a method for gesture detection and localisation based on multi-scale and multi-modal deep learning. Each visual modality captures spatial information at a particular spatial scale (such as motion of the upper body or a hand), and the whole system operates at three temporal scales. Key to our technique is a training strategy which exploits: i) careful initialization of individual modalities; and ii) gradual fusion involving random dropping of separate channels (dubbed ModDrop) for learning cross-modality correlations while preserving uniqueness of each modality-specific representation. We present experiments on the ChaLearn 2014 Looking at People Challenge gesture recognition track, in which we placed first out of 17 teams. Fusing multiple modalities at several spatial and temporal scales leads to a significant increase in recognition rates, allowing the model to compensate for errors of the individual classifiers as well as noise in the separate channels. Futhermore, the proposed ModDrop training technique ensures robustness of the classifier to missing signals in one or several channels to produce meaningful predictions from any number of available modalities. In addition, we demonstrate the applicability of the proposed fusion scheme to modalities of arbitrary nature by experiments on the same dataset augmented with audio.
Need Help ? Recommending Social Care Institutions

In this paper, we present work-in-progress on a recommender system designed to help people in need find the best suited social care institution for their personal issues. A key requirement in such a domain is to assure and to guarantee the person’s privacy and anonymity in order to reduce inhibitions and to establish trust. We present how we aim to tackle this barely studied domain using a hybrid contentbased recommendation approach. Our approach leverages three data sources containing textual content, namely (i) metadata from social care institutions, (ii) institution specific FAQs, and (iii) questions that a specific institution has already resolved. Additionally, our approach considers the time context of user questions as well as negative user feedback to previously provided recommendations. Finally, we demonstrate an application scenario of our recommender system in the form of a real-world Web system deployed in Austria.
Developing an extended technology acceptance model: Doctor's acceptance of electronic medical records in Jordan

The purpose of this study is to construct doctors’ acceptance model of Electronic Medical Records (EMR) in private hospitals.The model extends the Technology Acceptance Model (TAM) with two factors of Individual Capabilities; Self-Efficacy (SE) and Perceived Behavioral Control (PBC). The initial findings proposes additional factors over the original factors in TAM making Perceived Usefulness (PU), Perceived Ease Of Use (PEOU), Behavioral Intention to use (BI), SE, and PBC working in incorporation.A cross-sectional survey was used in which data were gathered by a personal administered questionnaire as the instrument for data collection.Doctors of public hospitals were involved in this study which proves that all factors are reliable.