Miracle-dz/UniFAR-FTUs huggingface dataset:
An Analytical Review and Extension of Two Decades of Research Related to PC-Crash Simulation Software

PC-Crash is a vehicular accident simulation software that is widely used by the accident reconstruction community. The goal of this article is to review the prior literature that has addressed the capabilities of PC-Crash and its accuracy and reliability for various applications (planar collisions, rollovers, and human motion). In addition, this article aims to add additional analysis of the capabilities of PC-Crash for simulating planar collisions and rollovers. Simulation analysis of five planar collisions originally reported and analyzed by Bailey [2000] are reexamined. For all five of these collisions, simulations were obtained with the actual impact speeds that exhibited excellent visual agreement with the physical evidence. These simulations demonstrate that, for each case, the PC-Crash software had the ability to generate a simulation that matched the actual impact speeds and the known physical evidence. Simulation of a full-scale rollover test reported by Asay [2010] is also examined. For this test, we obtained a simulation that exhibited an excellent visual match with the pre-roll tire marks and furrows and in which the vehicle rolled 7 times, just as it did in the actual test. The rest position of the vehicle was well matched, though a portion of the simulated roll trajectory did not match the actual roll trajectory. These areas of additional analysis extend the prior literature.
The Relevance of Financial and Non-Financial Compensation on Professionalism and Lecturers Performance: Evidence from Makassar Private Universities (Indonesia)

This study aimed to test empirically the effect of financial and non financial compensation on professionalism and lecturer’s performance. The study population was all lecturers who are certified, public and private lecturers at the private universities in Makassar (Indonesia). Stratified proportional random sampling was used to obtain the total sample of 111 lecturers’. Covariance-based SEM (SEMPLS) with a WarpPLS 5.0 used in this study. The results of the study provide evidence that financial and non financial compensation has a positive and significant effect on the lecturer’s professionalism. Financial compensation has a positive and significant effect on the lecturer performance but non financial compensation did not. The level of professionalism has a positive and significant effect on the lecturer’s performance. Professionalism can be evident as a mediating role in explained effect of financial and non financial compensation on lecturer’s performance.
A real-time monitoring tool for multicentre studies in cardiology

Especially in Cardiologic Multicentre Studies the collection, organization and statistical analysis of study data requires a sophisticated information support system. An ideal system should be easy accessible and should provide high security. For this reason Remote-Data-Entry is seen as the most promising future technology. Remote-Data-Entry is the method of collecting Data from different Sites remotely via an Interface emulation or in most cases a browser and writing it into a central database, where the data can be processed and distributed. This way of (Inter)net-based clinical data management is ideal for data entry from distributed locations that have little or no computer infrastructure. A still remaining lack of a system only with simple sewer-browser-user interaction is the missing possibility to verify source data and track Data bedside. For this reason our system integrates Palm-Devices, a Long-Term-ECG-Recorder and Fax-to-Mail Services for direct source- and bedside datacapture.
Effect of Lung Cancer Treatment on Health-Related Quality of Life

Effect of Lung Cancer Treatment on Health-Related Quality of Life Among Older Adults by Festus Frempong Dokyi MSPH, Walden University, 2006 MBA, MA, Webster University, 2002 BSc, University of Ghana, 1992 Dissertation Submitted in Partial Fulfillment of the Requirements for the Degree of Doctor of Philosophy Public Health
A coarse taxonomy of artificial immune systems

This work provides a high-level taxonomy of the field of Artificial Immune Systems (AIS). Specifically, the taxonomy presented is not application focused as is the case in de Castro and Timmis' seminal reference on the field [212], rather the field is presented firstly by computational paradigm, and secondary by so-called thrust of research. This secondary aggregation involves the subjective organisation of work based on authors involved and the theme of the presented research. The intent of this work is to provide both a high-level overview of the principle computational paradigms of the field and provide some indication of the major works and their relationships within each paradigm. This work is not a complete bibliography, rather it contains seminal and influencial works from each selected paradigm. Section 2 considers the general field of Artificial Immune Systems, and provides references regarding defintinios, overview of the field and conceptual frameworks. Section 3 considers those works inspired by the self-nonself principle refered to as the Negative Selection Paradigm. Section 4 considers those works inspired by Burnet's clonal selection theory refered to as the Clonal Selection Paradigm. Section 5 considers those works inspired by Jerne's immune network theory refered to as the Immune Network Paradigm. Section 6 considers those works inspired by Matzinger's danger theory refered to as the Danger Signal Paradigm. Section 7 considers those works that do not fit neatly into the selected organisation of the field. Finally, Section 8 considers works that focus on the distributed concerns of the immune system. The field of Artificial Immune Systems (AIS) is primarily concerned with the development, demonstration, and implementation of computational tools inspired by principles and processes of the vertebrate immune system. The field of artificial immune systems is not concerned with the theoretical or computational modelling of the biological system. Standard definitions of both the field of AIS and what comprises an artificial immune system follow. The authors de Castro and Von Zuben [210] define an AIS as " … a computational system based upon metaphors of the biological immune system ". They go on to define Immune Engineering (IE) as " … a meta-synthesis process that uses the information contained in the problem itself to define the solution tool to a given problem, and then apply it to obtain the problem solution ". The distinction is the IE is the engineering process, differentiated as to the conventional engineering process that uses ideas …
Distribution of lactate between red blood cells and plasma after exercise

Summary The distribution of lactate between blood cells and plasma, lactate concentration in whole blood and plasma, concentration of haemoglobin and packed cell volume (PCV) were measured in Standardbred and Finnhorse trotters. Red blood cell (RBC) lactate was calculated from whole blood and plasma lactate concentrations and PCV. Plasma lactate concentration correlated positively with whole blood lactate concentration over a range of exercise intensities (r = 0.972; P < 0.001). Similarly, plasma lactate concentration correlated with the calculated RBC lactate concentration both after the standardised submaximal exercise test (SET) and races, although there was individual variation in gradients. The slope of regression after the SET increased with sampling time, but such an effect was not found after the races. The mean corpuscular haemoglobin concentration did not show any correlation with RBC lactate concentration. Based on these results, we suggest that transport of lactate to erythrocytes occurs rapidly and is mainly determined by plasma lactate concentration. The great variation between individuals and individual similarity of plasma-cell concentration differences after submaximal and maximal exercise indicates that distribution of lactate between plasma and erythrocytes depends not only on plasma lactate concentration. Other factors, such as lactate transporter, may be important.
Effectiveness and safety of warm needle acupuncture on insomnia

Background: Warm needle acupuncture (WNA) combines acupuncture and moxibustion, which is an integral part of the acupuncture therapy. Insomnia is a common sleep disorder, which affects sub-healthy people and patients with chronic disease. The clinical practice indicates that WNA has a therapeutic effect on insomnia. Here we will provide a protocol to explore the effectiveness and safety of WNA for insomnia. Methods: We will search the randomized controlled trails (RCT) literatures of WNA for insomnia in 9 electronic databases, including 5 English databases [PubMed, Web of Science, EMBASE, the Cochrane Central Register of Controlled Trials (Cochrane Library), and WHO International Clinical Trials Registry Platform (TCTRP)] and 4 Chinese databases [Chinese National Knowledge Infrastructure (CNKI), Chinese VIP Information, Wanfang Database, and Chinese Biomedical Literature Database (CBM)]. Sleep quality value of the patient will be considered as the primary outcome and the secondary outcome will include biochemical, indicators total scores on the insomnia severity index, quality of life, adverse events caused by WNA, and changes of symptom in Traditional Chinese Medicine. The selection of the studies will be performed by EndnoteX7 software. All analyses will be conducted by using RevMan software V5.3. Result: This study will provide a rational synthesis of current evidences for warm needle acupuncture on insomnia. Conclusion: The conclusion of this study will provide evidence to judge the effectiveness and safety of WNA on insomnia. Registration: PROS-PERO CRD42018112645
Proc mixed - Trials and Tribulations

At GSK Proc Mixed is commonly being used to compare treatment or other differences in phase 1 crossover trials . In such trials there is variation between subjects and also variation within subjects. Proc Mixed is used because random effects can be used to describe these two sources of variation. Also subjects with missing observations can be handled without removing all of their data from the analysis. A fixed effect is a parameter which is modelled in the same way as in Proc GLM – there are pre-specified levels of that effect e.g. Treatment group which is predefined in a trial because the aim is to compare responses among the fixed groups. In contrast a random effect is a parameter whose values cause a random variability within a trial and whose values are not known pre-trial e.g. the subject responses in a trial. So commonly, subject is declared as a ‘random’ parameter within Proc Mixed to account for this randomness in the statistical analysis. The purpose of this paper is to provide a whistle-stop tour of the Proc Mixed procedure by describing some code that has been used to carry out an analysis on a phase 1 crossover trial in at GlaxoSmithKline. BACKGROUND Pharmacokinetics (PK) is the investigation of what the body is doing to the drug and so is an integral part of assessing the safety of a new compound. There are many parameters which are used to assess the PK of a compound for example , AUC (area under the curve for a concentration time plot) – if a compound has a large AUC then this indicates that the subject’s exposure to the drug is high and thus there maybe a lot of adverse events for that drug . Similarly for the PK parameter Cmax, which is the maximum concentration of the drug reached in the body, a high Cmax may lead to an increase in the number of adverse events that a subject experiences. Conversely a low Cmax is an indication of a slow absorption and may obscure the distribution of drug in the body, hence any factors that affect the value of Cmax are of interest. So, this paper will look at how the two factors of food status and the formulation of the drug affects the Cmax of a drug in a phase 1 trial using the SAS Proc Mixed procedure. Proc Mixed compares the means of the data using the least square means statistical procedure to measure any differences between groups of data.
Periphreal T-Cell Lymphoma not otherwise specified (PTCL-NOS) Variety in A 58 Year Old Male Patient in Oncology Ward J.P.M.C. Karachi: A Case Report

Background: Peripheral T cell Lymphoma is a heterogeneous form of non-hodgkin lymphoma, and encompasses many sub-types of which Peripheral T cell lymphoma not otherwise specified (PTCL-NOS) is the rare subset. Case presentation: A 58 years old farmer presented with multiple small to medium sized pruritic skin swellings on whole scalp, neck, face and inguinal region with bilateral axillary lymphadenopathy, patient denied any constitutional symptoms or rash. Tissue biopsy reported solid sheets of large atypical pleomorphic cells; Immunohistochemistry and histopathology findings favored the diagnosis of Peripheral T-cell Lymphoma Not Otherwise Specified. CT scan of brain, chest and abdomen excluded visceral involvement. Conclusion: This group of PTCL is aggressive in nature and requires standard combination chemotherapy upon diagnosis, through this report we highlight the variability of Peripheral T Cell Lymphoma’s clinical presentation.
On Suboptimal Solution of Antagonistic Matrix Games

The paper examines resource allocation games such as Colonel Blotto and Colonel Lotto games with the goal to develop tractable method for building suboptimal solution in mixed strategies of these games without solving the relevant optimization problem. The foundation of proposed method lies in the specific combinatorial properties of the partition games. It turned out that as far as distribution of resource along battlefield is concerned that pure strategies participating in e-optimal solution possessed specific structure. Numerical experiments showed that these specific structural peculiarities can be easily reproduced utilizing previously found combinatorial properties of partition. As a result, we get e-optimal solution of partition games and support set mixed strategies can be computed in polynomial time.
Cost-Sensitive Distributed Machine Learning for NetFlow-Based Botnet Activity Detection

The recent advancements of malevolent techniques have caused a situation where the traditional signature-based approach to cyberattack detection is rendered ineffective. Currently, new, improved, potent solutions incorporating Big Data technologies, effective distributed machine learning, and algorithms countering data imbalance problem are needed. Therefore, the major contribution of this paper is the proposal of the cost-sensitive distributed machine learning approach for cybersecurity. In particular, we proposed to use and implemented cost-sensitive distributed machine learning by means of distributed Extreme Learning Machines (ELM), distributed Random Forest, and Distributed Random Boosted-Trees to detect botnets. The system’s concept and architecture are based on the Big Data processing framework with data mining and machine learning techniques. In practical terms in this paper, as a use case, we consider the problem of botnet detection by means of analysing the data in form of NetFlows. The reported results are promising and show that the proposed system can be considered as a useful tool for the improvement of cybersecurity.
Connecting Resources: Which Issues Have to be Solved to Integrate CMC Corpora from Heterogeneous Sources and for Different Languages?

The paper reports on the results of a scientific colloquium dedicated to the creation of standards and best practices which are needed to facilitate the integration of language resources for CMC stemming from different origins and the linguistic analysis of CMC phenomena in different languages and genres. The key issue to be solved is that of interoperability-with respect to the structural representation of CMC genres, linguistic annotations metadata, and anonymization/pseudonymization schemas. The objective of the paper is to convince more projects to partake in a discussion about standards for CMC corpora and for the creation of a CMC corpus infrastructure across languages and genres. In view of the broad range of corpus projects which are currently underway all over Europe, there is a great window of opportunity for the creation of standards in a bottom-up approach.
Contribution à l'étude de la céramique islamique : analyse du matériel archéologique de RAHBA - MAYADIN (Syrie, vallée de l'Euphrate)

La synthese des travaux realises sur les sites de Mayadin et de Rahba, de 1976 a 1979, etudes de terrain et de la ceramique, confirme les donnees textuelles. La ville de Rahba, au bord du fleuve, a bien ete construite a l'epoque abbasside, dans la premiere moitie du IXe siecle. L'abandon de cette premiere ville se situe au moment ou les textes ne font reference qu'a la citadelle et a son role defensif, face aux invasions mongoles. L'evolution de la seconde ville de Rahba, au bord du plateau, est etroitement liee a l'activite de la citadelle. La periode des Xe-XIe siecles, mal connue sur d'autres sites, est relativement bien representee a Rahba. Un atelier de fabrication de ceramique en est la principale illustration. L'etude des produits a permis de mettre en evidence des influences perses. Leur repartition, dans la moyenne vallee de l'Euphrate, correspond au territoire domine par les Mirdasides, pendant la periode d'independance de Rahba. Pour la periode de la fin du XIe au XIIIe siecle, les plans des bâtiments mis au jour sont originaux : a l'epoque seljoukide - zankide, les maisons, de plan carre, sont organisees autour d'une cour centrale sur laquelle s'ouvrent des iwans. Ces plans sont tres proches de modeles afghans. Leur evolution a l'epoque ayyoubide reflete le souci d'adapter les logements a une concentration de la population. Le grand bâtiment sonde au pied de la citadelle, dans la seconde ville de Rahba, est un exemple d'architecture publique, probablement une mosquee. Enfin, l'analyse de la place de Rahba au sein des differentes zones de distribution des ceramiques, a travers les epoques, met en valeur l'evolution des echanges economiques dans la moyenne vallee de l'Euphrate et l'importance des ensembles geopolitiques successifs.
Applying an Ecosystem Approach to the Determinants of Health in Centro Habana

The difficult economic times that Cuba has had to face have taken a considerable toll on its urban ecosystems, with data suggesting that indicators of health, the environment, and social services have been deteriorating. This has been particularly evident in Centro Habana, a municipality with the highest population density in the country. More than half the population was without daily access to potable water, waste disposal was insufficient, overcrowding was serious, disease vectors were prevalent, and rates of various infectious as well as noncommunicable diseases and injuries were highest in the country. To improve the situation, the municipality requested help from the National Institute for Hygiene Epidemiology and Microbiology (INHEM) to determine the best use of scarce resources to improve health. INHEM performed an ecological descriptive study and conducted focus groups in five communities to assess perceptions of health, social, and environmental factors, followed by a household survey. INHEM then engaged collaborators at the University of Manitoba to assist in developing a framework, analyzing the data, and planning and undertaking the evaluation requested. Maximum likelihood factor analysis was used to reduce the dimensionality of the data. The perception data were then merged with the ecological level health and environmental data to ascertain the relationship between these two data sources and determine which indicators might be useful for an intervention analysis. The perception results indicated that the greatest community concern was quality of housing, but that the risk perception results were independent of ecological data on morbidity, mortality, and basic sanitation indicators. Based on this conclusion, it was decided to use a combined qualitative and quantitative approach to evaluate actual and potential interventions, using the driving force-pressure-state-exposure-effects-action (DPSEEA) framework. It was also decided to adopt an ecosystem approach that fully involves the community in developing a set of ecosystem human health indicators. Data from repeat focus groups and household surveys are planned, with these data to again be integrated with ecological data including environmental, socioeconomic, and health outcome information, using a pre- versus postintervention with concurrent control design. Our findings in this first phase indicated that an ecosystem framework is invaluable in ascertaining determinants of health and prioritizing and evaluating interventions to improve the health of communities.
New approach for high order-high frequency analogue micropower filter design

A novel design approach for high frequency analogue micropower filters employing weakly inverted MOSFETs is presented. By vertically connecting integrators instead of the classical horizontal cascade, filter topologies can be realised with extremely low power, and high frequency performance. To support the concepts, a 60 nW, 100 kHz biquad low-pass filter is designed with 1.8 V supply voltage. Also, a 112 nW, 100 kHz fourth-order Chebyshev coupled-biquad low-pass filter is also designed with 2 V supply voltage. Simulation results using a 0.8 /spl mu/m CMOS process confirm the design.
Common wisdom versus facts: How entrepreneurs differ in their behavioral traits from other occupational groups

Sinds het invloedrijke werk van Knight (1921) heeft er veel onderzoek plaatsgevonden naar ondernemers en wat hen zo verschillend maakt van anderen. Als gevolg daarvan is er nu een redelijke brede literatuur die suggereert dat ondernemers fundamenteel verschillen in bijvoorbeeld hun risicopreferenties, (over)optimisme en hun meer intuitieve denkstijl. Hoewel voorgaande aannemelijk klinkt, is de literatuur echter zeker niet eenduidig in de conclusies hieromtrent. Dit in tegenstelling tot de vele blogs op internet, waar men met veel bravoure de verschillen tussen ondernemers en anderen uiteen weet te zetten. Het doel van dit proefschrift is daarom tweedelig: (1) verder inzicht verkrijgen in de verschillen tussen ondernemers en anderen, in ons geval managers en werknemers, en (2) testen in hoeverre de algemene wijsheid op internet hout snijdt. Aangezien er vele interessante deelgebieden zijn te bedenken waarop men ondernemers, managers en werknemers met elkaar kan vergelijken, hebben we ons gelimiteerd tot de volgende vier gedragskenmerken waar de wetenschappelijke literatuur en de blogs het meeste aandacht aan lijken te besteden: houding ten aanzien van risico en onzekerheid (Hoofdstuk 2), optimisme en zelfoverschatting (Hoofdstuk 3), intuitieve versus contemplatieve besluitvorming (Hoofdstuk 4) en de voorkeur voor alleen werken versus in een team (Hoofdstuk 5). Wat denkt u dat ondernemers anders maakt dan managers en werknemers?
"Boxed In or Out? Balikbayan Boxes as Metaphors for Filipino American (Dis)Location"

Balikbayan (from the Tagalog words balik, to return, and bayan, town or nation) boxes, which mostly contain pasalubong, or gifts, for relatives and friends, are staples in the transnational existence of many Filipinos and have come to represent the balikbayans, or the returning persons, themselves. Utilizing the rites of passage concept and the dialectic of gift-giving, reciprocity and reproduction, this article looks at balikbayan boxes as metaphors for the dislocation experienced and felt by many first-generation Filipino Americans. It presents the preparation of the boxes as an allegory for the bonds that bind Filipino Americans to those who remain in the Philippines. In reading these boxes as a location of balikbayan identity, it emphasizes the liminal status of first generation Filipino Americans both in their native and adopted countries.