Miracle-dz/UniFAR-FTUs huggingface dataset:
Tipos de encuestas considerando la dimensión temporal

Longitudinal research and survey research The first part of the paper reviews the abilities of alternative survey design across time: prospective design, retrospective studies, cross-sectional surveys, cohort surveys, panel survey. The second part concentrates in panel surveys. It discusses the decision and need to be made in design a panel survey, the problem of nonresponse, time in sample bias and the seam effect, and some problems.
PrimerMiner : an R package for development and in silico validation of DNA 1 metabarcoding primers 2 3

PrimerMiner: an R package for development and in silico validation of DNA 1 metabarcoding primers 2 3 Vasco Elbrecht *, Florian Leese 1,2 4 5 Affiliations: 6 1) Aquatic Ecosystem Research, Faculty of Biology, University of Duisburg-Essen, Universitätsstraße 5, 45141 Essen, 7 Germany 8 2) Centre for Water and Environmental Research (ZWU) Essen, University of Duisburg-Essen, Universitätsstraße 2, 45141 9 Essen, Germany 10 *Corresponding author: vasco.elbrecht@uni-due.de, phone: +49.201-1834053 11 12 Abstract 13 1) DNA metabarcoding is a powerful tool to assess biodiversity by amplifying and sequencing a standardized gene marker 14 region. Its success is often limited due to variable binding sites that introduce amplification biases. Thus the development of 15 optimized primers for communities or taxa under study in a certain geographic region and/or ecosystems is of critical 16 importance. However, no tool for obtaining and processing of reference sequence data in bulk that serve as a backbone for 17 primer design is currently available. 18 2) We developed the R package PrimerMiner, which batch downloads DNA barcode gene sequences from BOLD and 19 NCBI databases for specified target taxonomic groups and then applies sequence clustering into operational taxonomic units 20 (OTUs) to reduce biases introduced by the different number of available sequences per species. Additionally, PrimerMiner 21 offers functionalities to evaluate primers in silico, which are in our opinion more realistic then the strategy employed in 22 another available software for that purpose, ecoPCR. 23 3) We used PrimerMiner to download cytochrome c oxidase subunit I (COI) sequences for 15 important freshwater 24 invertebrate groups, relevant for ecosystem assessment. By processing COI markers from both databases, we were able to 25 increase the amount of reference data 249-fold on average, compared to using complete mitochondrial genomes alone. 26 Furthermore, we visualized the generated OTU sequence alignments and describe how to evaluate primers in silico using 27 PrimerMiner. 28
Connecting stellar mass and star-formation rate to dark matter halo mass out to z ∼ 2

We have constructed an extended halo model (EHM) which relates the total stellar mass and star-formation rate (SFR) to halo mass (M_h). An empirical relation between the distribution functions of total stellar mass of galaxies and host halo mass, tuned to match the spatial density of galaxies over 0 < z < 2 and the clustering properties at z ∼ 0, is extended to include two different scenarios describing the variation of SFR on M_h. We also present new measurements of the redshift evolution of the average SFR for star-forming galaxies of different stellar masses up to z = 2, using data from the Herschel Multi-tiered Extragalactic Survey for infrared bright galaxies. Combining the EHM with the halo accretion histories from numerical simulations, we trace the stellar mass growth and star-formation history in haloes spanning a range of masses. We find that: (1) the intensity of the star-forming activity in haloes in the probed mass range has steadily decreased from z ∼ 2 to 0; (2) at a given epoch, haloes in the mass range between a few times 10^(11) M_⊙ and a few times 10^(12) M_⊙ are the most efficient at hosting star formation; (3) the peak of SFR density shifts to lower mass haloes over time; and (4) galaxies that are forming stars most actively at z ∼ 2 evolve into quiescent galaxies in today's group environments, strongly supporting previous claims that the most powerful starbursts at z ∼ 2 are progenitors of today's elliptical galaxies.
The use of a novel residuum model to design a variable-impedance transtibial prosthetic socket

For people living with limb amputation, the prosthetic socket the interface between the residuum and prosthesis is the most critical component. When a socket is uncomfortable, especially due to poor fit, the quality of life for a patient is greatly hindered. However, conventional design of sockets is largely artisan, with limited input of quantitative data. Current computer-aided and manufacturing (CAD/CAM) designs are still not clinically applicable solutions. Due to model identification procedures that employ non patientspecific and incomplete data sets, today's finite element (FE) models of the residuum are not predictive, leading to suboptimal socket designs. As such, there exists a need for a comprehensive biomechanical model of the residuum for the quantitative design and computational evaluation of patient-specific prosthetic sockets. This thesis presents a combined experimental-numerical approach to evaluate and validate a transtibial residuum biomechanical model. The central hypothesis of the work is that a single biomechanical model can predict the large non-linear response at various sites on a residuum under load. To evaluate this hypothesis, a non-linear, two-tissue model was formulated where tissue geometries were defined using MRI data of the residuum. The non-linear viscoelastic material parameters of the model were identified through inverse FEA-based optimization using in-vivo indentation experimental data at four locations. Using optimized model tissue parameters, the mean percentage error (mean absolute error/ maximum experimental force) between the experimental and simulation force-time curves at 14 other locations across the evaluated transtibial residuum was 7 3%. Using this same modeling methodology and a single set of material constants to describe the bulk soft tissue biomechanical response of seven distinct transtibial residual limb models, the average percentage error for indentations at multiple locations across all seven limbs was 7 1%. From these predictive models of residuum limbs, one rigid novel socket and two multimaterial transtibial sockets were designed, fabricated and evaluated through an entirely quantitative, automated and repeatable methodology. In a preliminary clinical investigation, the novel sockets were shown to reduce peak contact pressures at the tibia and fibular head regions on the residuum by significant amounts during standing compared to a conventional socket interface designed and fabricated by a trained prosthetist. Thesis Supervisor: Hugh M. Herr Title: Associate Professor of Media Arts and Sciences
Complexity of neutralization antibodies against multiple dengue viral 2 serotypes after heterotypic immunization and secondary infection revealed by 3 in-depth analysis of cross-reactive antibodies 4 5

JVI00273-15 revised 1 Complexity of neutralization antibodies against multiple dengue viral 2 serotypes after heterotypic immunization and secondary infection revealed by 3 in-depth analysis of cross-reactive antibodies 4 5 Wen-Yang Tsai, Anna Durbin, Jih-Jin Tsai, Szu-Chia Hsieh, Stephen Whitehead, 6 Wei-Kung Wang 7 8 Department of Tropical Medicine, Medical Microbiology and Pharmacology, John A. Burns 9 School of Medicine, University of Hawaii at Manoa, Honolulu, Hawaii, USA; Center for 10 Immunization Research, Department of International Health, Johns Hopkins Bloomberg School 11 of Public Health, Baltimore, Maryland, USA; Tropical Medicine Center and Divison of 12 Infectious Diseases, Department of Internal Medicine, Kaohsiung Medical University Hospital, 13 Department of Internal Medicine, School of Medicine, Kaohsiung Medical University, 14 Kaohsiung, Taiwan; Laboratory of Infectious Diseases, National Institute of Allergy and 15 Infectious Diseases, National Institutes of Health, Bethesda, Maryland, USA 16 17 † These authors contributed equally to this work. 18 Address correspondence to Wei-Kung Wang, wangwk@hawaii.edu 19 20
THE FACTORS THAT CONTRIBUTE TO PARENTAL RESPONSIVENESS IN ADOPTIVE FAMILIES

The level of responsiveness of parents as they interact with their children is considered to be one of the most significant characteristics for children’s cognitive, language, social and emotional development. To the extent that adopted children are at risk for developmental problems, the manner in which adoptive parents’ style of interaction promote children’s development is critical. In an effort to understand adoptive parents’ style of interacting with their children, the main purpose of this study is to identify factors that contribute to adoptive parents’ levels of responsiveness. Guided by the Transactional Model of Development and Belsky’s Model of Parenting, three research questions, the basis of this study, address the associations between characteristics of parents, characteristics of children, and social context characteristics and the level of responsiveness of adoptive parents. This study is a secondary analysis of data from 41 adoptive parents and their young children who participated in the Developmental PARTners (Prevention, Assessment, Referral, and Training for young adopted children) model demonstration project funded by the United States Department of Education and conducted between 2005 and 2007 at Case Western Reserve University in Cleveland, OH. This study found an association between parental responsiveness (e.g., Affect)
Patch loading - analytical approach to critical load determination

The problem of plate stability under patch-loading can be analyzed using a variety of mathematical models by which the problem can be more or less realistically described. Models adopted in this paper serve as the basis for checking applicability of the analytical solution when subjected to complex load conditions. The accuracy of the procedure, proven by comparison with the data obtained through numerical models, and achieved by introduction of the exact stress function and use of appropriate deflection functions, confirms correctness of the solution presented in the paper.
Análisis de datos cualitativos

El analisis de datos en la investigacion cualitativa es un proceso que toma tiempo, mas aun, si el investigador esta empezando en esta labor, maxime cuando en ocasiones no se conoce la definicion de las palabras: analisis y adjetivo cualitativo. Por consiguiente, el objetivo de este articulo, es conocer los pasos mas importantes dentro de la investigacion cualitativa para realizar el analisis. A lo largo de este documento, encontrara conceptos que enriqueceran la investigacion y los pasos relevantes que se deben tener cuenta, antes de llegar a hacer el analisis cualitativo. Realizar el analisis en la investigacion cualitativa es complejo, porque en la mayoria de los casos, se recoge mucha informacion, para hacer esto se requiere tiempo y disposicion; esta labor podra facilitarse con algunos programas que son utilizados en los trabajos de investigaciones cualitativas, y finalmente se terminara presentando las estrategias para hacer un analisis de datos cualitativo.
Secondary metabolites of ripe fleshy fruits: ecology and phylogeny in the genus Solanum.

Why do ripe fleshy fruits contain secondary metabolites, sometimes in concentrations that make the fruits toxic to vertebrates? And how do the chemical and physical characteristics of fruits influence choice by frugivores? These questions have drawn the attention of those interested in understanding the adaptive roles of fruit traits (see Cipollini and Levey, 1997a, b,c; Cipollini, 2000). However, a criticism of such studies is that few have addressed the possible influence of physiological and phylogenetic constraints on fruit traits (see Cipollini and Levey, 1998; Eriksson and Ehrlen, 1998). We are addressing this concern by studying fruit traits of the genus Solanum, while assessing and accounting for phylogenetic effects. Here we provide a preliminary analysis of our data, which we hope will stimulate others to conduct similar analyses. Theoretically, predictable differences in the quality of seed dispersal among frugivores should influence the evolution of fruit traits (see Janson, 1983; Wheelwright, 1985; Jordano 1987a; Debussche and Isenmann, 1989; Willson et al., 1989; Gautier-Hion, 1990; Stiles and Rosselli, 1992). Nevertheless, studies using phylogenetic null models have not supported this theory (see Bremer and Eriksson, 1992; Herrera, 1992; Jordano, 1995). This lack of support is assumed to result, in part, because of extensive decoupling of interactions between particular frugivores and the plants whose seeds they disperse (see Howe, 1984; Jordano, 1987b; Herrera, 1998). However, most studies on the evolution of fruit traits have overlooked the effects of secondary metabolites, which are probably important mediators of fruit– frugivore interactions (Cipollini and Levey, 1997c, 1998). We have presented several adaptive hypotheses on the adaptive significance of secondary metabolites in ripe fleshy fruits (Cipollini, 2000). In general, these hypotheses assume a selective advantage to plants bearing fruits containing secondary metabolites and thus predict that patterns of secondary chemistry in fruits can be explained, at least in part, by interactions with frugivores. Likewise, the hypotheses
Defense Technical Information Center Compilation Part Notice ADP 012379 TITLE : Chemical Generation of Atomic Iodine for COIL

A method of the chemical production of atomic iodine aimed for application in COIL was studied experimentally. The method is based on chemical generation of chlorine atoms and their subsequent reaction with hydrogen iodide. Effects of initial ratio of reactants and the way of their mixing were investigated and interpreted by means of the developed model of the reaction system. In optimum conditions, the yield of iodine atoms, related to HI, attained 70 100 %.
Localization Through Low Power Techniques

The increasing use of navigation in day to day life drives the interest to develop more sophisticated mobile applications. Navigation is based on periodic localion update. The update procedure can be achieved in many ways. The selection of optimistic technique is very essential to increase the accuracy, precision, speed of updating, the correctness of the technique in any given situation and in any given place. This paper discusses and evaluates all the possible localization techniques. It also describes what technique to use in a given situation and discusses the pros and cons of using the remaining techniques. Power consumption is also quite challenging in localization. Reducing power consumption attracts wider range of audience. Hence an efficient solution to reduce the power consumption is proposed in this paper. Finally the results of using the low power technique with all the discussed localization techniques is been demonstrated and a real time situation which gets highly benifited using the low power solution along with the best suitable location finding technique is described.
Survey of Investigation on Ranking of Active Web Forum Users

The World Wide Web consists of millions of interconnected web pages that provide information to the user present in any part of the world. The World Wide Web consists of the web forums, where active Web users participate and post their comments. The influential users dominate and influence the newly joined innocent users through their thoughts. The activeness of a user is captured by a measure based on the degree of match of the commented posts with a complete list. Hence it is necessary to retrieve the best and the influential user who frequently participate and post their right message that are more relevant in terms of information for the query entered by the user in the search engine. The proposed algorithm is weighted ranking algorithm for accurate identification of active users. This includes about five metrics to identify the influential users. The process starts with a data crawling and preprocessing step in which the URL of the forum home page is passed to the forum crawler, which crawls all relevant web pages and eliminates the duplicates heuristically. Users can use the web services and provide their feedbacks on the forum. All these data’s are stored in the log file. Their comments are compared with the threat list. From the list, the most influential users are listed out based on the session count and the session time of users.
Possible Therapeutic Effect of Arsenic Trioxide and L-Carnitine on Hepatocellular Carcinoma Induced in Rats C Research

The present study aimed to evaluate the therapeutic effect of arsenic trioxide (AS2O3) and L-carnitine on hepatocellular carcinoma (HCC)-induced in rats using diethylnitrosamine (DENA) followed by carbon tetrachloride (CCL4). Fifty male (10-12 weeks old) Wistar albino rats were randomly assigned to five groups namely normal control, carcinogenic, cisplatin, AS2O3 and L-carnitine groups. Assessed biomarkers included serum alkaline phosphatase (ALP), total bilirubin (tBil), alanine transaminase (ALT), aspartate transaminase (AST), albumin and total protein as hepatocyte integrity parameters, serum tumor marker alpha-fetoprotein (AFP), hepatic malondialdehyde (MDA), glutathione reduced (GSH) and superoxide dismutase (SOD) as oxidative stress biomarkers. Histopathology and immunohistochemistry of P53 were also conducted. AS2O3 and L-carnitine significantly improved hepatic functions as indicated by significant reduction in serum ALP, tBil, ALT and AST. In addition, Lcarnitine attenuated oxidative stress biomarkers. Histopathological and immunohistochemistry P53 findings strongly supported results of biochemical estimations. AS2O3 and L-carnitine have therapeutic effect on HCCinduced in rats; possibly through enhancement of tumor cells apoptosis by AS2O3 and protective effect of mitochondria by L-carnitine.
1H-NMR based metabonomics as a potential tool to assess cardiotoxicity in drug development

Introduction Currently, the main cause of drug post-approval withdrawal from the market is cardiovascular toxicity. Indeed, safety cardiovascular issues account for 45% of the total postapproval withdrawal, compared to 32% for hepatic issues (1). The severity and the high incidence of cardiovascular toxicity in the late-stage of clinical drug development can lead to several consequences : restrictions of medical use, special preand/or post-approval monitoring and drug withdrawal. However, cardiovascular toxicity accounts only for 9% of drug attrition during phase I of clinical development (2). The data suggest that there is a need to develop more predictive methods to assess cardiotoxicity in preclinical studies and in early stages of clinical trials to avoid the progression of drug candidates with a high risk for the cardiovascular system. Therefore, a H-NMR based metabonomics was used to reassess the cardiotoxicity of 2 nonsteroidal anti-inflammatory drugs (NSAIDs), Diclofenac and Rofecoxib, recently incriminated with an increased incidence of heart infarct (3,4).
Galvinoxyl monolayers on Au(111) studied by STM, EPR, and cyclic voltammetry

Galvinoxyl layers on Au(111) have been studied by scanning tunnelling microscopy (STM), electron paramagnetic resonance (EPR), and cyclic voltammetry (CV). We observe two phases: configuration I having a molecular density of $1.57\ifmmode\pm\else\textpm\fi{}0.16\ifmmode\times\else\texttimes\fi{}{10}^{\ensuremath{-}10}\phantom{\rule{0.3em}{0ex}}\mathrm{mol}∕{\mathrm{cm}}^{2}$ and a rectangular lattice ($15\phantom{\rule{0.3em}{0ex}}\mathrm{\AA{}}$ by $7\phantom{\rule{0.3em}{0ex}}\mathrm{\AA{}}$) observed at room temperature and down to $140\phantom{\rule{0.3em}{0ex}}\mathrm{K}$; configuration II with a slightly smaller molecular density of $1.37\ifmmode\pm\else\textpm\fi{}0.14\ifmmode\times\else\texttimes\fi{}{10}^{\ensuremath{-}10}\phantom{\rule{0.3em}{0ex}}\mathrm{mol}∕{\mathrm{cm}}^{2}$ and oblique cells ($22.5\phantom{\rule{0.3em}{0ex}}\mathrm{\AA{}}$ by $5.4\phantom{\rule{0.3em}{0ex}}\mathrm{\AA{}}$) arranged alternatingly in stacks yielding a molecular layer with lower symmetry and comparatively large crystallographic unit cell. The latter is only observed upon cooling down to $40\phantom{\rule{0.3em}{0ex}}\mathrm{K}$ and subsequent annealing to room temperature. For both assemblies typical domain sizes in the range of $100\phantom{\rule{0.3em}{0ex}}\mathrm{nm}$ have been found. The EPR results confirm that the radical character is preserved upon adsorption and that the intermolecular distance is smaller than $11\phantom{\rule{0.3em}{0ex}}\mathrm{\AA{}}$. The interaction between the overlapping singly occupied spin orbitals is high, indicating no participation of the unpaired electron in the binding to the surface or laterally between neighboring radicals. The average surface concentration deduced from CV measurements is in excellent agreement with the surface coverages deduced from STM topographies. In aqueous electrolyte the adsorbate undergoes a one-electron oxidation with concomitant loss of a proton as determined from oxidation potential vs $p\mathrm{H}$ curves in a similar fashion as known for the free radical in solution. This indicates no dramatic change of the electronic properties of the radical upon adsorption. Structure models are proposed with molecules standing upright like ``bicycles in rows. ''
Estudo do aumento espontâneo na velocidade de partículas em transportadores de correia

Investigamos algumas propriedades do material granular que influenciam no fenomeno observado de aumento espontâneo da componente horizontal da velocidade das particulas. Foram realizadas simulacoes computacionais onde se percebe a variacao da velocidade, considerando o atrito entre graos, a vazao do fluxo granular e a coesao entre os graos. Mostramos que o atrito entre graos aproxima o escoamento do comportamento de um solido granular.
1 1 cdi-GMP Signaling Regulates Intracellular Aggregation , Sessility , 2 and Growth of Ehrlichia chaffeensis 3 4 5

Running title: E. chaffeensis morula and c-di-GMP 14 15 *Corresponding author. Mailing address: Department of Veterinary Biosciences, 16 College of Veterinary Medicine, The Ohio State University, 1925 Coffey Road, 17 Columbus, Ohio 43210-1093. Phone: (614) 292-9677. Fax: (614) 292-6473. E-mail: 18 rikihisa.1@osu.edu. 19 20 Current address: Research Institute for Microbial Diseases, Osaka University, 21 Yamada-oka 3-1, Suita, Osaka 5650871, Japan. 22 23 Copyright © 2011, American Society for Microbiology and/or the Listed Authors/Institutions. All Rights Reserved. Infect. Immun. doi:10.1128/IAI.05320-11 IAI Accepts, published online ahead of print on 25 July 2011
Q A ] 9 A ug 2 00 5 Covariant q-differential operators and unitary highest weight representations for U q su n , n

We investigate a one-parameter family of quantum Harish-Chandra modules of Uqsl2n. This family is an analog of the holomorphic discrete series of representations of the group SU(n, n) for the quantum group Uqsun,n. We introduce a q-analog of ”the wave” operator (a determinant-type differential operator) and prove certain covariance property of its powers. This result is applied to the study of some quotients of the above-mentioned quantum Harish-Chandra modules. We also prove an analog of a known result by J. Faraut and A. Koranyi on the expansion of reproducing kernels which determines the analytic continuation of the holomorphic discrete series. Table of contents