Miracle-dz/UniFAR-FTUs huggingface dataset:
Near-wordless document structure classification

Automatic derivation of logical document structure from generic layout would enable the development of many highly flexible electronic document manipulation tools. This problem can be divided into the segmentation of text into pieces and the classification of these pieces as particular logical structures. This paper proposes an approach to the classification of logical document structures, according to their distance from predefined prototypes. The prototypes consider linguistic information minimally, thus relying minimally on the accuracy of OCR and decreasing language-dependence. Different classes of logical structures and the differences in the requisite information for classifying them are discussed. A prototype format is proposed, existing prototypes and a distance measurement are described, and performance results are provided.
A Novel WLAN Positioning Technique Employing Time Delay of Successful Transmission

There are many approaches in literatures using the knowledge of time delay to locate the user position in WLAN system. All of them have to modify the existing WLAN infrastructure. The scales of modifications are made on hardware up to the changes in protocol of WLAN. Hence, it is an unattractive approach to use time delay for positioning system. In this paper, the new concept of utilizing time day of successful transmission to locate the position of WLAN user is presented. The advantage of using the proposed technique is no extra modification necessarily appended in the existing system. The measurement results confirm the validation of proposed concept.
Quantitative imaging and measurement of cell–substrate surface deformation by digital holography

Quantitative phase microscopy by digital holography (DH-QPM) is introduced to study the cell–substrate interactions and migratory behavior of adhesive cells. A non-wrinkling elastic substrate, collagen-coated polyacrylamide (PAA) has been employed and its surface deformation due to cell adhesion and motility has been visualized as certain tangential and vertical displacement and distortion. The surface deformation on substrates of different elasticity and thickness has been quantitatively imaged and the corresponding cellular traction force of motile fibroblasts has been measured from phase profiles by DH-QPM. DH-QPM is able to yield quantitative measures directly and provide efficient and versatile means for quantitatively analyzing cellular motility.
An Auto-Scaling Framework for Containerized Elastic Applications

Mechanisms for automatic resource provisioning in cloud environment have been widely studied. However, most current work are based on Virtual Machines(VMs) and few auto-scaling systems dedicated for containerized environment have been presented. This paper proposes an auto-scaler that caters for containerized elastic applications. We devise a hybrid scaling strategy based on a resource demand prediction model to meet Service Level Agreements(SLAs) in face of quickly varying workloads. We implemented our system in a private container-centric cloud environment and experimental results demonstrate that our auto-scaling framework out-performs existing rule-based approaches.
Sedentary Behavior, Psychosocial Stress Indicators, and Health-Risk Behaviors Among Adolescents in Northeastern Brazil.

OBJECTIVES To analyze psychosocial stress indicators and health-risk behaviors associated with sedentary behavior. METHODS This is a cross-sectional school-based study with a representative sample of high school students enrolled in public state schools of Sergipe, Brazil, with the sample composed of 3992 adolescents aged 14-19 years. Data were collected through self-administered questionnaire. The time spent in activities, such as watching television, playing computer games, chatting with friends, and playing cards or dominoes, was used as a measure of sedentary behavior (>2 h/d = exposed). Level of physical activity, smoking, stress perception, feelings of loneliness, trouble sleeping, and consumption of fruits and vegetables, soft drinks, alcohol, and drugs were analyzed. Binary logistic regression analysis was used for association among variables. RESULTS The prevalence of sedentary behavior was 46.7% and was associated with low levels of physical activity, consumption of soft drinks, negative stress perception, feelings of loneliness, and trouble sleeping. CONCLUSION This study showed high proportion of adolescents with sedentary behavior, especially among those who are insufficiently active and exposed to psychosocial stress indicators.
Covariant perturbations of anisotropic cosmological models.

In this paper I use the covariant approach to study the evolution of linear perturbations in a Bianchi type-I cosmology. It is found that the evolution of density perturbations is described by a fourth-order system of differential equations as in the treatment of Perko, Matzner, and Shepley for the case of a pressureless perfect fluid and I verify that these equations are consistent using the set of linear constraint equations. I then show that when the shear is axially symmetric this system reduces to one second-order differential equation for the density gradient. Approximate solutions are found for the case of dust, which are in agreement with earlier studies
New miRNA expression abnormalities in laryngeal squamous cell carcinoma.

BACKGROUND Although the development of novel diagnostic and treatment strategies concerning laryngeal cancer is highly intensive, the survival rate remains virtually unchanged. Small non-coding RNAs appear to be very promising biomarkers - and so remain the focus of extensive investigation in laryngeal cancer. OBJECTIVE We examined the expression of five miRNA and five genes related to cancer whether they could be potential laryngeal cancer biomarkers. METHODS We performed an analysis in 47 patients diagnosed with laryngeal cancer. The qPCR technique was used to investigate the expression profile. RESULTS While miR-21-3p and miR-525-5p were found to be significantly up-regulated, miR-139-3p and miR-885-5p expression is lower in laryngeal cancer. Moreover, PIK3R1 and HACE1 were found to be also down-regulated. CONCLUSIONS The change in miRNA expression is frequent than the expression of other tested genes. The expression of passenger strands such as miR-21-3p and miR-139-3p, which are rarely investigated, is also significantly affected in laryngeal cancer. While PIK3R1, HACE1, miR-139-3p, and miR-885-5p may act as tumor suppressor genes in the studied tumour type, miR-21-3p and miR-525-5p seem to have oncogenic properties. Our findings suggest that miR-885-5p and PIK3R1 are the best indicators for the classification of laryngeal cancer tissue and normal mucosa.
Self Reported Depressive Symptomatology in Adolescents: A Psychometric Study

This study attempts to explore cultural-specific manifestation and expression of depressive symptomatology in adolescents. 40 school children referred by their teachers to the school counsellors were interviewed to explore the expression of depressive symptomatology. A list of 32 elicited items was given to 10 school counselors for empirical validation. All those items receiving 90% agreement from the experts were retained. A final list of 27 items converted into a self report measure (Depressive Symptomatology Scale, DSS) was piloted on 30 children. In the final phase, a 385 participants selected through stratified sampling were given the DSS, the Self-Concept Scale (Perveen, Saleem, & Mahmood, 2011), and the Child Depression Inventory (1992) for concurrent validity and a demographic performa. Principal Component Factor analysis yielded a four factor solution; Sadness, Indecisiveness, Irritability and Psychosomatic symptoms. The DSS was found to have high internal consistency, test-retest reliability, and concurrent and discriminant validity. Results are discussed in terms of gender differences, school counseling and cultural differences.
Programming for Non-Volatile Main Memory Is Hard

Using non-volatile memory as main memory (NVMM) can largely improve the performance of applications, but adds to the challenge of programming -- it turns out to be very error-prone to write real-world NVMM programs, especially with object-oriented programming. This paper presents a field study of erroneous NVMM programs written by programmers who are trained to use a general NVMM programming interface. We performed the field study in a training workshop of 30 participants. Our observations and derived best practices offer a reference for future NVMM programming techniques design. Toward that end, we propose a taxonomy of latest NVMM programming techniques and, accordingly, a set of paradigms that can reduce the risk of NVMM-specific bugs. The paradigms incorporate a minimal NVMM library interface design and a new design pattern inspired by the field study.
Nucleotide Sequence of a Portion of the Camphor-degrading Gene Cluster from Rhodococcus sp. NCIMB 9784

Rhodococcus sp. NCIMB 9784 is a camphor-degrading Gram-positive organism originally isolated from activated sewage sludge. A 5.4 kbp portion of a proposed camphor degradation gene cluster from this organism was cloned and its nucleotide sequence determined. Four open reading frames (ORFs) were identified encoding proteins possibly involved in camphor metabolism; sequence alignment of the translation products suggested that the ORFs encode for a ferredoxin reductase, acyl-CoA ligase, epimerase and an acyl-CoA dehydrogenase. The last three activities are thought to be involved in the poorly understood late stage of camphor degradation. Our findings are entirely consistent with the proposed formation of a branched 9-carbon acid intermediate (3,4,4-trimethyl-5-oxo-trans-2-hexenoic acid) which has been isolated from the fermentation broth of camphor-grown cells.
Patient Adoption of Smart Cards Full paper

This paper adapts the Unified Theory of Acceptance and Use Technology Model (UTAUT) to assess the factors impacting the adoption of smart cards in Medicaid Health Home context. We contribute to the theory by including three constructs specific to smart card and health devices: (i) concern for error, (ii) sickness orientation (iii) concern for data security. Utilizing a survey design we collected responses from 116 participants who are ethnic minorities, enrolled in a Medicaid Health Home program or from a highrisk population. We developed a conceptual model and an instrument to measure the patient’s likelihood to use the smart card. The concern for error, social influence and sickness orientation significantly impact the likelihood to use the smart card. Our results show that patients are more concerned about prevention of errors as compared to security breaches.
Mutations in the TIR 1 Auxin Receptor That Increase Af fi nity for Auxin / Indole-3-Acetic Acid Proteins Result in Auxin Hypersensitivity 1 [ W ] [ OA ]

The phytohormone auxin regulates virtually every aspect of plant development. The hormone directly mediates the interaction between the two members of the auxin coreceptor complex, a TRANSPORT INHIBITOR RESPONSE (TIR1)/AUXIN SIGNALING F-BOX protein and an AUXIN/INDOLE-3-ACETIC ACID (Aux/IAA) transcriptional repressor. To learn more about the interaction between these proteins, a mutant screen was performed using the yeast (Saccharomyces cerevisiae) two-hybrid system in Arabidopsis (Arabidopsis thaliana). Two tir1 mutations were identified that increased interaction with Aux/IAAs. The D170E and M473L mutations increase affinity between TIR1 and the degron motif of Aux/IAAs and enhance the activity of the SCF complex. This resulted in faster degradation of Aux/IAAs and increased transcription of auxin-responsive genes in the plant. Plants carrying the pTIR1:tir1 D170E/M473L-Myc transgene exhibit diverse developmental defects during plant growth and display an auxinhypersensitive phenotype. This work demonstrates that changes in the leucine-rich repeat domain of the TIR1 auxin coreceptor can alter the properties of SCF.
Influence of binding on the vibrational responses of targeted lipid-coated microbubbles

Microbubbles for molecular ultrasound imaging are targeted to disease-specific biomarkers. One of the main challenges is to acoustically distinguish free microbubbles from those that are bound to their molecular target. In this study we used the Brandaris 128 high-speed camera to compare the responses to ultrasound of two types of lipid-coated microbubbles (DSPC and DPPC) in their free and bound state aiming to acoustically discriminate them. We found larger shrinkage for DPPC than for DSPC microbubbles in both their free and bound condition, indicating higher acoustical stability for DSPC-based microbubbles. Upon binding the stability of both types did not change significantly. Frequencies of maximum response were similar for DSPC and DPPC microbubbles, whether they were free or bound. In their free state, more DPPC than DSPC microbubbles responded at the subharmonic and the second harmonic frequency, which did not change upon binding. Interestingly, the maximum relative radial excursions at the second harmonic frequency were higher for DSPC microbubbles when they had bound. In conclusion, bound DSPC and DPPC microbubbles had lower maximum relative radial excursions at the fundamental frequency, and had higher maximum relative radial excursions at the second harmonic frequency than the free microbubbles. We found no differences between bound DSPC and bound DPPC microbubbles. The higher maximum relative radial excursions of particularly bound DSPC microbubbles at the second harmonic frequency may provide opportunities to acoustically discriminate them from free microbubbles.
Orexins induce increased Excitability and Synchronisation of Rat Sympathetic Preganglionic Neurones

The neuropeptides orexin A and B are synthesised by perifornical and lateral hypothalamic (LH) neurones and exert a profound influence on autonomic sympathetic processes. LH neurones project to spinal areas containing sympathetic preganglionic neurones (SPNs) and therefore may directly modulate sympathetic output. In the present study we examined the possibility that orexinergic inputs from the LH influence SPN activity. Orexin‐positive neurones in the LH were labelled with pseudorabies virus injected into the liver of parasympathetically denervated animals and orexin fibres were found adjacent to the soma and dendrites of SPNs. Orexin A or B (10–1000 nm) directly and reversibly depolarised SPNs in spinal cord slices. The response to orexin A was significantly reduced in the presence of the orexin receptor 1 (OX1R) antagonist SB334867A at concentrations of 1–10 μm. Single cell reverse transcriptase‐polymerase chain reaction revealed expression of mRNA for both OX1R and OX2R in the majority of orexin‐sensitive SPNs. The orexin‐induced depolarisation involved activation of pertussis toxin‐sensitive G‐proteins and closure of a K+ conductance via a protein kinase A (PKA)‐dependent pathway that did not require an increase in intracellular Ca2+. Orexins also induced biphasic subthreshold membrane potential oscillations and synchronised activity between pairs of electrically coupled SPNs. Coupling coefficients and estimated junctional conductances between SPNs were not altered indicating synchronisation is due to activation of previously silent coupled neurones rather than modulation of gap junctions. These findings are consistent with a direct excitation and synchronisation of SPNs by orexinergic neurones that in vivo could increase the frequency and coherence of sympathetic nerve discharges and mediate LH effects on sympathetic components of energy homeostasis and cardiovascular control.
Clarification of mural cell coverage of vascular endothelial cells by live imaging of zebrafish

Mural cells (MCs) consisting of vascular smooth muscle cells and pericytes cover the endothelial cells (ECs) to regulate vascular stability and homeostasis. Here, we clarified the mechanism by which MCs develop and cover ECs by generating transgenic zebrafish lines that allow live imaging of MCs and by lineage tracing in vivo. To cover cranial vessels, MCs derived from either neural crest cells or mesoderm emerged around the preformed EC tubes, proliferated and migrated along EC tubes. During their migration, the MCs moved forward by extending their processes along the inter-EC junctions, suggesting a role for inter-EC junctions as a scaffold for MC migration. In the trunk vasculature, MCs derived from mesoderm covered the ventral side of the dorsal aorta (DA), but not the posterior cardinal vein. Furthermore, the MCs migrating from the DA or emerging around intersegmental vessels (ISVs) preferentially covered arterial ISVs rather than venous ISVs, indicating that MCs mostly cover arteries during vascular development. Thus, live imaging and lineage tracing enabled us to clarify precisely how MCs cover the EC tubes and to identify the origins of MCs. Highlighted article: Live imaging of mural cell dynamics in zebrafish shows how the mural cells develop and cover the endothelial cells during vascular development.
Miniaturized Ultra-Wideband Self-Complementary Antennas Using High Permittivity Thick Resin Material

A miniaturized self-complementary antenna for Japanese UWB higher band (7.25 GHz-10.25 GHz) is demonstrated. Input impedances of four antennas in the size of 30 mm, 20 mm, 15 mm, 10 mm each on 1 mm and 2 mm thick high permittivity (epsivr = 10.2 ) resin substrates were measured and extracted. With the extracted input impedance, 50 Omega-matched self-complementary antennas in the size of 10 mm were designed and fabricated. The measured return loss was less than -10 dB between 5.9 GHz and 13.8 GHz and the fractional bandwidth was 80%. The fabricated antenna size is almost equivalent with the broadband antenna's minimum size Chu showed [1]. Measured radiation patterns were almost omni-directional between 6 GHz and 12 GHz.
Complete Genome Sequence of Brucella abortus Strain BCB034, a Strain of Biovar 2 Isolated from Human

ABSTRACT Brucella abortus is divided into eight biovars, of which biovars 1 to 3 are the most frequently represented biovars in strains isolated from humans. Here, we report the genome sequence of B. abortus strain BCB034, a strain isolated from a human patient and that belongs to biovar 2.
Aerobic, Anaerobic, and Excess Postexercise Oxygen Consumption Energy Expenditure of Muscular Endurance and Strength: 1-Set of Bench Press to Muscular Fatigue

Scott, CB, Leighton, BH, Ahearn, KJ, and McManus, JJ. Aerobic, anaerobic and excess postexercise oxygen consumption energy expenditure of muscular endurance and strength: 1-set of bench press to muscular fatigue. J Strength Cond Res 25(4): 903-908, 2011-We use a new approach to the estimation of energy expenditure for resistance training involving nonsteady state measures of work (weight × displacement), exercise O2 uptake, blood lactate, and recovery O2 uptake; all lifts were performed to muscular failure. Our intent was to estimate and compare absolute and relative aerobic and anaerobic exercise energy expenditure and recovery energy expenditure. Single-set bench press lifts of ∼37, ∼46, and ∼56% (muscular endurance-type exercise) along with 70, 80, and 90% (strength-type exercise) of a 1 repetition maximum were performed. Collectively, the muscular endurance lifts resulted in larger total energy expenditure (60.2 ± 14.5 kJ) as compared with the strength lifts (43.2 ± 12.5 kJ) (p = 0.001). Overall work also was greater for muscular endurance (462 ± 131 J) as opposed to strength (253 ± 93 J) (p = 0.001); overall work and energy expenditure were related (r = 0.87, p = 0.001). Anaerobic exercise and recovery energy expenditure were significantly larger for all strength lifts as compared with aerobic exercise energy expenditure (p < 0.001). For the muscular endurance lifts, anaerobic energy expenditure was larger than recovery energy expenditure (p < 0.001) that in turn was larger than aerobic exercise energy expenditure (p < 0.001). We conclude that for a single set of resistance training to fatigue, the anaerobic and recovery energy expenditure contributions can be significantly larger than aerobic energy expenditure during the exercise. To our surprise, recovery energy expenditure was similar both within strength and muscular-endurance protocols and between protocols; moreover, recovery energy expenditure had little to no relationship with aerobic and anaerobic exercise energy expenditure or work.
New Diagram for Cleft Lip and Palate Description: The Clock Diagram

Objectives: The current classification diagrams for cleft lip and palate are descriptions of the components involved in the cleft, but they do not consider in detail the severity of distortion. We sought to establish a new diagram (the Clock Diagram) for cleft lip and palate, which describes the pathology according to the severity of distortion of the nose, lip, and primary and secondary palate, and to apply this classification scheme toward treatment selection. Methods: The method is based on surgical results obtained from 1043 cleft lip and palate patients operated by the author between 1996 and 2007, under the protocol based on our classification. To further illustrate the classification and diagram method, two types of clefts are described, using the proposed diagram and compared with Kernahan's diagram. Results: This new diagram describes the cleft's severity using terminology from our clinic's classification of cleft severity. In comparison with Kernahan's diagram, the Clock Diagram more effectively demonstrates a cleft's severity. I have observed a higher incidence of lip and palate revision in severe clefts. Conclusions: The Outreach Program Lima Clock Diagram classifies the severity of the cleft and affords an individualized description of cleft morphology. I have observed a direct relation between cleft severity and the number of poor outcomes in our patients.
C18orf2, a novel, highly conserved intronless gene within intron 5 of the GNAL gene on chromosome 18p11

We have characterized a novel intronless human gene (C18orf2) which is embedded in intron 5 of the G-protein gene (GNAL) on chromosome 18p11. This gene codes for a 199 amino acid polypeptide with a predicted molecular weight of 22.1 kDa. It is highly homologous to a number of predicted developmental proteins in organisms ranging from yeasts to Drosophila. C18orf2 mRNA was found to be expressed in various tissues.
Dissociation of Adult Mouse Liver by Sodium Tetraphenylboron, A Potassium Gomplexing Agent.∗

Summary 1. Sodium tetraphenylboron (TPB), a specific agent for complexing K+ has been found to dissociate adult mouse liver in vitro into a suspension of single cells. 2. Evidence is presented that this is the result of the removal of K+, which is the major cation involved in aggregation of cells in this tissue. 3. A coordination mechanism for aggregation is proposed in which the negatively charged surfaces in cell-cell aggregates or in cell-matrix-cell aggregates are neutralized by monovalent cations. 4. Two variables of coordination mechanisms, i.e., cation coordinated and the coordination number are used in a model advanced to explain ordered movement and aggregation of cells in tissues.