Miracle-dz/UniFAR-FTUs huggingface dataset:
Reproduction in the male

Physiology of the mammalian testis, G.M. H.Waites and B.P.Setchell spermatogenesis in mammals and birds, Marie-Therese Hochereau de Reviers et al Spermatogensis in teleost fish, R.Billard male life cycle and seasonality, T.D. Glover et al the mammalian spermatozoon - morphology, biochemistry and physiology, J.M. Bedford and D.D. Hoskins biochemistry of the male accessory glands, D.E. Brooks anatomy of mammalian male accessory reproductive organs, D.W. Hamilton artificial insemination and the preservation of semen, P.F. Watson artificial insemination in fish, R.Billard.
Theoretical Studies into the Spectral Characteristics, Biological Activity, and Photovoltaic Cell Efficiency of Four New Polycyclic Aromatic Chalcones

Abstract In the present work, the molecules, (E)-1-(4,4″-difluoro-5′-methoxy-1,1′:3′,1″-terphenyl-4′-yl)-3-phenylprop-2-en-1-one (DFTP), (2E)-1-(4,4″-difluoro-5′-methoxy-1,1′:3′,1″-terphenyl-4′-yl)-3-(4-fluorophenyl)prop-2-en-1-one (TFTP), (2E)-3-(4-bromophenyl)-1-(4,4″-difluoro-5′-methoxy-1,1′:3′,1″-terphenyl-4′-yl)-prop-2-en-1-one (BFTP), and (E)-1-1(4,4″-difluoro-5′-methoxy-1,1′:3′-1″-terphenyl-4′-yl)-3-(4-methylphenyl)prop-2-en-1-one (FMTP) have been synthesized and vibrational wavenumbers and electronic properties have also been performed. The compound series shows good light harvesting properties and photovoltaic modeling shows that they can be used successfully in DSSCs as photo sensitizers. The NLO activity of the title compounds have been investigated and β and γ values varies in the order BFTP > FMTP > TFTP > DFTP. The consequences which were made by electron donor acceptor due to charge transfer mechanism have been scrutinized by the natural bond investigation. Molecular docking has been performed to understand the binding interactions of the analyzed ligands with tyrosine-protein kinase JAK2 and these compounds can be developed as anticancer agent.
Feeding ecology of kererū (Hemiphaga novaeseelandiae) in podocarp-hardwood forest, Whirinaki Forest Park, New Zealand

The diet and food preferences of the kererū (Hemiphaga novaeseelandiae) were studied in Whirinaki Forest Park, central North Island, New Zealand, during February 2000 - March 2001. The study was carried out in two areas of podocarp-hardwood forest, Oriuwaka (1750 ha) and Otupaka (1830 ha). Fruit dominated in the diet at both sites (65% in Oriuwaka, 87% in Otupaka), but there were seasonal changes. Foliage and flowers were more important in the diet in winter and spring, but the timing of the switch from fruit to foliage differed between the areas. The main fruit eaten also changed seasonally from tawa (Beilschmiedia tawa) in early summer to miro (Prumnopitys ferruginea) in late summer and autumn. Variation in diet partly reflected seasonal phenology of the plants and differences in vegetation between the two areas, but when food-type availability is considered, kererū showed selective preference for some food types at some times. Miro and tawa fruits were highly preferred food types in both areas. This study highlights the likely need of kererū to have access to various vegetation types in order to meet their seasonally changing nutritional requirements in a podocarp-hardwood forest where the availability of food, especially fruits, can differ markedly both in time and space. Thus, large forest blocks that contain a variety of habitat types, or landscapes containing patches of various habitat types, are needed for the long-term conservation of kererū populations.
Cichla cataractae (Cichliformes: Cichlidae), new species of peacock bass from the Essequibo Basin, Guyana and Venezuela

ABSTRACT. A new species of peacock bass, Cichla cataractae, is distinguished from all congeners by molecular evidence and unique patterns of adult and juvenile pigmentation. Juveniles (<150 mm SL) have sides of body dominated by a series of three conspicuous dark blotches with the one below soft dorsal fin largest, attenuated posteriorly (long teardrop shape) but distinctly separated from elliptical caudal blotch; same blotches eventually with pale border (ocellated) in largest juveniles. Adult pattern on sides dominated by two distinct dark blotches, each one ocellated; anterior blotch rounded, located below anterior base of spinous dorsal fin and not extending above anterior lateral line; posterior blotch highly irregular in shape, located below soft dorsal fin and often displaced dorsally; additional dark blotch below posterior base of spinous dorsal fin generally absent or small, ocellated or not, and level with anterior blotch; vertical bars on sides generally absent or faint; postorbital stripe always present, highly broken into irregular series of dark spots, each one usually ocellated. Cichla cataractae is endemic to the Essequibo Basin where it typically inhabits rocky shoals in river channels with swift current. The new species is sympatric with the more widely distributed C. ocellaris, a species that prefers lentic habitats. Molecular analysis supports C. cataractae as a distinct lineage in a clade of Cichla containing C. temensis, C. melaniae, C. mirianae, C. piquiti and C. pinima. The oldest extant specimens of the new species were collected by Carl H. Eigenmann in 1908 and documented in his seminal "The Freshwater Fishes of British Guiana" (Eigenmann, 1912).
Innovation of impairment loss allowance model of Indonesian financial accounting standards 71

PurposeThis study aims to develop a high-quality impairment loss allowance model in conformity with Indonesian Financial Accounting Standards 71 (PSAK 71) that has significant contribution to national interests and the banking industry.Design/methodology/approachThe determination of the impairment loss allowance model is settled through 7 stages, using integration of some statistical methods such as Markov chain, exponential smoothing, time series analysis of behavioral inherent trends of probability of default, tail conditional expectation and Monte Carlo simulation.FindingsThe model which is developed by the authors is proven to be a high-quality and reliable model. By using the model, it can be shown that the implementation of the expected credit losses model on Indonesian Financial Accounting Standards 71 is more prudent than the implementation of the incurred loss model on Indonesian Financial Accounting Standards 55.Research limitations/implicationsDetermination of defaults was based on days past due, and the analysis in this study did not touch the aspects of hedge accounting in general.Practical implicationsThis developed model will contribute significantly to national interests as a source of reference for other banks operating in Indonesia in calculating impairment loss allowance (CKPN) and can be used by the Financial Services Authority of Indonesia (OJK) as a guideline in assessing the formation of impairment loss allowance for banks operating in Indonesia.Originality/valueAs so far there is not yet an available standardized model for calculating impairment loss allowance on the basis of Indonesian Financial Accounting Standards 71, the model developed by the authors will be a new breakthrough in Indonesia.
Practical work design based on Science, Technology, Engineering, Mathematics (STEM) on manufacture of liquid sugar from cassava peel waste (Manihot esculenta) to improve student creativity

The aim of this study is to create a practical work design based on science, technology, engineering and mathematics (STEM) on the manufacture of liquid sugar from cassava husks (Manihot esculenta) to improve the creative abilities of students. To achieve this, the question that arises in this study is “How can the characteristics of developing practical design based on science, technology, engineering and mathematics improve students’ creativity? " The researcher used Design-Based Research (DBR) method consisting of 4 phases: Problem identification and analysis, Designing a solution, Repeated cycles in testing and refining designs and Reflection to produce the principles of design and implementation. The Participants in this study were senior high school students, chemistry teacher and 3 observers who understood the STEM approach. Data was collected by interviewing, testing and observing the activities students. The results showed that student creativity increased through STEM-based practice.
Analysis of the ability of mathematical connections of middle school students in the field of algebra

The world of education continues to innovate in various fields, including renewal in its implementation strategies. Mathematical connection ability is one of the important abilities possessed by students. Mathematical connections aim to link mathematical problems into mathematical ideas they have. If students can use mathematical connections, learning will be optimal and meaningful. This study aims to describe students’ mathematical connection skills in solving the problem of mathematical connections in the algebraic field. This research uses descriptive qualitative research with the subject of the research is class VIII in Surakarta Batik Middle School, amounting to 57 students. Data collection is done by giving a test in the form of a more in-depth essay on mathematical connection skills in the algebraic field. The variables in this study are indicators of mathematical connection ability, namely the connection between mathematical concepts, connections between mathematics and other sciences, and connections between mathematics and everyday life. In this study, students’ mathematical connection ability tests were still low. Can be seen from the percentage of each indicator, namely the indicator of the connection between mathematical concepts is 38%, the connection between mathematics and other sciences is 29%, and the connection between mathematics and everyday life is 43%. Students are lowest in connecting mathematics with other sciences.
Family Name Origins and Intergenerational Demographic Change in Great Britain

We develop bespoke geospatial routines to typify 88,457 surnames by their likely ancestral geographic origins within Great Britain. Linking this taxonomy to both historic and contemporary population data sets, we characterize regional populations using surnames that indicate whether their bearers are likely to be long-settled. We extend this approach in a case study application, in which we summarize intergenerational change in local populations across Great Britain over a period of 120 years. We also analyze much shorter term demographic dynamics and chart likely recent migratory flows within the country. Our research demonstrates the value of family names in characterizing long-term population change at regional and local scales. We find evidence of selective migratory flows in both time periods alongside increasing demographic diversity and distinctiveness between regions in Great Britain.
Cell wall composition regulates cell shape and growth behaviour in pollen tubes

One of the most important features characterizing plant cells and differentiating them from animal cells is the cell wall that surrounds them. The cell wall plays a critical role in providing protection to the protoplast; it acts as a filtering mechanism and is the location of many biochemical reactions implicated in the regulation of the cell metabolism and the mechanical properties of the cell. The local stiffness, extensibility, plasticity and elasticity of the different cell wall components determine the shape and geometry of the cell during differentiation and morphogenesis. The goal of my thesis is to understand the role played by the different cell wall components in shaping the plant cell and controlling its growth behaviour. To achieve this goal, I studied the pollen tube, or male gametophyte, as a cellular model system. The pollen tube is a cellular protuberance formed by the pollen grain upon its contact with the stigma. Its main purpose is to deliver the sperm cells to the female gametophyte to ensure double fertilization. The pollen tube is a tip-growing cell characterized by its simple cell wall composition and by the fact that it is the fastest growing cell of the plant kingdom. This makes it the ideal model to study the effects of drugs, mutations or stresses on cellular growth behaviour, metabolism and cell wall mechanics. The pollen tube cell wall consists mainly of proteins and three major polysaccharidic components: pectins, cellulose and callose. To understand the role played by these components in regulating pollen tube growth, I investigated the effects of mutations, enzymatic treatments, hyper-gravity and omni-directional gravity on the pollen tube cell wall. Using mathematical modeling combined with molecular biology and highresolution electron and fluorescent microscopy I was able to show that the regulation of pectin chemistry is required for the regulation of the growth rate and pollen tube shape and that cellulose is crucial for determining the pollen tube diameter in the sup-apical region. Moreover, I investigated the role of the pectate lyases, a group of pectin digesting enzymes expressed during pollen tube development, and I showed that this enzyme activity is required for the initiation of pollen germination. More importantly, I directly showed for the first time that the pollen tube secretes cell wall loosening enzymes to facilitate its penetration through the style.
Adaptive geometric control of quadrotors with dynamic offset between center of gravity and geometric center

A geometric adaptive control of quadrotors has been proposed in this paper when the center of gravity of the quadrotor is different from its geometric center. The unique feature of the controller is the use of left tracking error function to simplify controller design. The inertia matrix, mass as well as the center of gravity are assumed to be unknown and coordinate invariant adaptive laws have been derived for the estimate of these mentioned parameters. The coordinate invariant approach is another unique feature of the proposed method as opposed to the literature. Rigorous mathematical proofs have been prescribed to show the stability of the complete closed loop dynamics under the proposed adaptive laws. The controller has been derived under the assumption that the rotational dynamics is faster than the translational dynamics. Numerical simulations have been shown at the end to show the effectiveness of the proposed method.
ZOLMITRIPTAN BRAIN TARGETING VIA INTRANASAL ROUTE USING SOLID LIPID NANOPARTICLES FOR MIGRAINE THERAPY: FORMULATION, CHARACTERIZATION, IN-VITRO AND IN-VIVO ASSESSMENT

Objective: Zolmitriptan, a class of antidepressant drugs with poor bioavailability due to its first-pass metabolism. The aim of this study was to improve systemic bioavailability and explore the brain targeting impact of nasal Zolmitriptan (Zol) solid lipid nanoparticles (SLNs) gel for migraine treatment. Methods: Stearic acid and cholesterol used as solid lipid and lecithin as a surfactant, emulsion solvent evaporation technique was used to produce Zolmitriptan SLNs. (Zol) SLNs were characterized for particle size, percent entrapment efficiency and in vitro drug release. Formula S6 showed greater percent entrapment efficiency (PEE), adequate particle size and sustained drug release behavior. Formula S6 was integrated into HPMC gel (3%) to prepare nasal gel. Zol SLN nasal gel was subjected to histopathological study to ensure brain targeting. Results: It was observed that all prepared Zol SLNs were in the nano-sized range with a polydispersity index of<0.5. In the cholesterol/lecithin combination, higher PEE%, better stability, and less agglomeration inclination were discovered. Results of the release profiles showed that developed Zol-SLNs were able to release Zolmitriptan in a sustained manner. Histopathological study of the brain tissues showed that Zolmitriptan SLN nasal gel can reach brain cells and localized for 24 h although the hydrophobicity of the target drug. Conclusion: Intranasal administration of Solid lipid nanostructure of Zolmitriptan through the olfactory pathway in which it travels from the nasal cavity to brain tissue achieved drug targeting potential of about 90% compared with conventional Zolmitriptan tablets. The small particle size helped them to squeeze themselves through the small opening in the olfactory neurons to the brain via different endo-cystic pathways of neuronal cells in nasal tissue membranes.
Higher-Order Spectral Analysis of Stray Flux Signals for Faults Detection in Induction Motors

Abstract This work is a review of current trends in the stray flux signal processing techniques applied to the diagnosis of electrical machines. Initially, a review of the most commonly used standard methods is performed in the diagnosis of failures in induction machines and using stray flux; and then specifically it is treated and performed the algorithms based on statistical analysis using cumulants and polyspectra. In addition, the theoretical foundations of the analyzed algorithms and examples applications are shown from the practical point of view where the benefits that processing can have using HOSA and its relationship with stray flux signal analysis, are illustrated.
Assessment of Scientific Literacy Skills of College of Education Students in Nigeria

The study randomly sampled one hundred and thirty-three integrated science students of a College of Education to assess their scientific literacy skills. The study was a survey design method. Data for the study was obtained through both qualitative and quantitative approaches. The research instruments were the Scientific Literacy Skills Test (SLST) and a semi-structured interview protocol. Eight skills were investigated which were grouped into three clusters. The study provided answers to three research questions. Data obtained were analyzed using the statistical tools of the t-test, descriptive statistics and thematic coding. Findings showed that students did not possess the scientific literacy skills required for them to function effectively after graduation in society. Besides, male students possessed more scientific literacy skills than their female counterparts in all three clusters of skills examined. Also, finding revealed that students used scientific literacy skills to solve real-life problems such as taking decisions and solving security problems. The paper made some recommendations for further study to enhance students’ scientific literacy skills.
Terrestrial Evaporation and Moisture Drainage in a Warmer Climate

To determine hydrologic changes in a warmer climate, we impose precipitation and potential evaporation (Eo) perturbations on hydrologic response functions constructed from precipitation and satellite soil moisture observations across the United States. Despite nonlinearities in the evaporation (E) and drainage (D) responses and opposing‐sign perturbations, changes in individual fluxes are superposable. Empirical frameworks (Budyko) can misrepresent changes in E/D partitioning by neglecting shifts/trends in hydrologic regime and subseasonal precipitation dynamics. E/D both increase to balance mean precipitation ( P¯ ) increases, and increased Eo reduces soil moisture. E and D are generally more elastic to changes in P¯ than Eo. The results suggest that (1) the impacts of regional hydrologic perturbations may allow for simple superposition/scaling, (2) changes in timing/intensity of precipitation may have substantial impacts on mean moisture states and fluxes, and (3) changes to the distribution of surface moisture states are likely more relevant for E/D partitioning than common aridity indices.
Influence of ammonium and moisture on survival and nifH transcription in the diazotrophic Pseudomonas mendocina S10

Nitrogen is important for crop productivity and usually added in form of urea into the soil which negatively affects the environment. It is important to utilize nitrogen fixing bacteria for improving the nitrogen content of soil in India. Here, we have isolated nitrogen fixing-bacteria Pseudomonas mendocina S10 from rhizospheric soil and studied its nitrogenase activity along with its survival under sterile soil conditions. Enterobacterial Repetitive Intergenic Consensus (ERIC) PCR and Real-time quantitative PCR were employed to investigate the population and nifH transcripts level respectively in presence of ammonium and moisture additives. Strain S10 was capable of growth and expressing nifH transcripts in the presence of 2.5 mM ammonium and 20 percent water availability. Population of isolated strain and it’s nifH mRNA was found at low levels when exposed to 5 mM ammonium for 60 days of incubation period. However, viable bacterial count and nifH transcript levels remained low in the presence of 1.25 mM ammonium and zero percent water content. These findings indicate that isolated strain could tolerate ammonium up to 5 mM for 60 days and can maintained their cell viability in low moisture conditions. Results revealed the advantage of using gene expression to evaluate the physiological state of microorganism’s population in soil.
The Legacy of the Past Logging: How Forest Structure Affects Different Facets of Understory Plant Diversity in Abandoned Coppice Forests

Predicting how biodiversity affects ecosystem functioning requires a multifaceted approach based on the partitioning of diversity into its taxonomic and functional facets and thus redundancy. Here, we investigated how species richness (S), functional diversity (FD) and functional redundancy (FR) are affected by forest structure. Sixty-eight abandoned coppice-with-standards plots were selected in two mountain areas of the Apennine chain. We performed linear models to quantify the influence of structural parameters on S, FD and FR of clonal traits. Each diversity facet was affected differently by structural parameters, suggesting a complex interweaving of processes that influence the understory layer. Namely, tree layer density influences S, the height of the standards affects the lateral spread and persistence of clonal growth organs, and diameter of standards affects the FD of the number of clonal offspring. Opposite relationships compared to FD was found for the FR, suggesting how clonal traits play a key role in species assemblage. The observation that structural parameters exert opposite impact on FR seems to indicate a counterbalance effect on ecosystem stability. Multifaceted approaches yield a better understanding of relationship between forest structure and understory, and this knowledge can be exploited to formulate indications for more sustainable management practices.
The effect of food intake on the pk of rhein released from diacerein

Diacerein is a symptomatic slow-acting drug used for treating osteoarthritis. This drug is completely metabolized into the active metabolite rhein before reaching the systemic circulation. This study evaluated the effects of food on the pharmacokinetics of rhein released from diacerein in healthy Chinese subjects. This was a single-center, randomized, single-dose, open-label, two-period, cross-over study. Twentyfour healthy subjects were randomly selected to receive a single oral dose of 50 mg diacerein capsule in either fasted or fed state on two separate visits. Plasma samples were analyzed with LC-MS/MS. Pharmacokinetic parameters were calculated using WinNonlin software. In the fasted and fed states, the main pharmacokinetic parameters of diacerein capsule were as follows: Cmax were (4471 ± 936), (3225 ± 755) ng/mL, t1/2 were (4.22 ± 0.42), (4.19 ± 1.05) h, tmax were (2.61 ± 1.25), (3.81 ± 1.29) h, AUC0-24 h were (24223 ± 4895), (24316 ± 5856) h·ng/mL, and AUC0-∞ were (24743 ± 5046), (25170 ± 6415) h·ng/mL. The absorption rate of diacerein capsule was obviously delayed by food intake but the absorption degree remained unaffected.