Miracle-dz/UniFAR-FTUs huggingface dataset:
PROMOTING ACADEMIC COMPETENCE IN TWO LANGUAGES: A CASE STUDY OF A BILINGUAL BA DEGREE (IN ENGLISH AND SESOTHO SA LEBOA) AT THE UNIVERSITY OF LIMPOPO

Our paper shows how using an African language as medium of instruction and assessment along with English can promote academic competence in both languages among university students. We do this by theorizing a dual-medium undergraduate degree (BA in Contemporary English and Multilingual Studies, BA CEMS) that we launched at the University of Limpopo in South Africa in 2003. In this paper, we describe the curricular structure of the degree and analyse the anatomy of one unit of learning: ‘Small Talk’, a low-prestige genre in African societies and an under-researched one globally. We use Cummins’ four-quadrant model to capture two kinds of learner effort, namely, language use and language study. We show a bi-directional transfer of skills across English and Sesotho sa Leboa, which upholds our claim that despite their differential historical and material status, they can be resources for each other to achieve academic excellence. We believe that bilingual education can facilitate the acquisition of language competence, especially for students who have had inadequate access to English at school and who struggle with the cognitive and linguistic demands of higher education.
Relevance of the TRIAP1/p53 axis in colon cancer cell proliferation and adaptation to glutamine deprivation

Human TRIAP1 (TP53-regulated inhibitor of apoptosis 1; also known as p53CSV for p53-inducible cell survival factor) is the homolog of yeast Mdm35, a well-known chaperone that interacts with the Ups/PRELI family proteins and participates in the intramitochondrial transfer of lipids for the synthesis of cardiolipin (CL) and phosphatidylethanolamine. Although recent reports indicate that TRIAP1 is a prosurvival factor abnormally overexpressed in various types of cancer, knowledge about its molecular and metabolic function in human cells is still elusive. It is therefore critical to understand the metabolic and proliferative advantages that TRIAP1 expression provides to cancer cells. Here, in a colorectal cancer cell model, we report that the expression of TRIAP1 supports cancer cell proliferation and tumorigenesis. Depletion of TRIAP1 perturbed the mitochondrial ultrastructure, without a major impact on CL levels and mitochondrial activity. TRIAP1 depletion caused extramitochondrial perturbations resulting in changes in the endoplasmic reticulum-dependent lipid homeostasis and induction of a p53-mediated stress response. Furthermore, we observed that TRIAP1 depletion conferred a robust p53-mediated resistance to the metabolic stress caused by glutamine deprivation. These findings highlight the importance of TRIAP1 in tumorigenesis and indicate that the loss of TRIAP1 has extramitochondrial consequences that could impact on the metabolic plasticity of cancer cells and their response to conditions of nutrient deprivation.
Exploring the complexity of smallholders' intense use of glyphosate in maize crops from South Mexico: Remarks for an ongoing agroecological transition

Recently, Mexico has launched policies of agroecological transition that seek to foster healthier agri-food systems. One of these policies is the reduction and eventual elimination of glyphosate by 2024. Despite being the most used herbicide in Mexico and the world, little information exists about what factors determine a greater or reduced use of glyphosate in different socio-ecological contexts. This study aimed to explore different agricultural management, biophysical and social variables and their effects on glyphosate use in maize crops by smallholders (<8 ha). A questionnaire and semi-structured interviews were performed with 142 farmer families in four regions of the state of Chiapas to document the use of herbicides and glyphosate. By using regression trees, we identified those variables that determine a greater or lesser use of glyphosate for each region and jointly. The average volume of glyphosate for the four regions during an agricultural cycle was 2.7 l/ha−1. Sets of variables were associated with syndromes of greater use of glyphosate and herbicides in general, such as small plots (<0.67 ha), indigenous population, younger farmers, fewer family members, rainfed conditions, and plots without mechanization. These results can help the design of contextualized and flexible policies of transition, consistent with the socio-ecological heterogeneity of Mexico.
Activity of single ion channel proteins detected with a planar microstructure

We present recordings of currents mediated by single ion channel proteins obtained using planar, microstructured glass chips. In these chips, pores with diameters of 1–2 μm are produced by ion track etching and are used for patch clamping instead of using the classical micropipette. Our results represent success in using such devices to record from single channels in cell membranes. The planar chip greatly enhances the accessibility of the ion channel containing membrane and can serve as a workbench for experiments on single ion channels using combinations of patch clamp current recording with other single molecule techniques.
Analog shaping optimization for digital processing of radiation detector signals

The necessary shapings for optimum processing of signals from radiation detectors can be conveniently obtained by using an analog prefilter followed by an A/D converter (ADC) and a digital filter. In this paper we analytically calculate the dependence of resolution and efficiency of energy measurements on the characteristics of the analog prefilter architecture. Consequent design rules of the analog stage are derived and different solutions are proposed and discussed.
New Approaches in Multi-View Clustering

Many real-world datasets can be naturally described by multiple views. Due to this, multi-view learning has drawn much attention from both academia and industry. Compared to single-view learning, multi-view learning has demonstrated plenty of advantages. Clustering has long been serving as a critical technique in data mining and machine learning. Recently, multi-view clustering has achieved great success in various applications. To provide a comprehensive review of the typical multi-view clustering methods and their corresponding recent developments, this chapter summarizes five kinds of popular clustering methods and their multi-view learning versions, which include k -means, spectral clustering, matrix factorization, tensor decomposition, and deep learning. These clustering methods are the most widely employed algorithms for single-view data, and lots of efforts have been devoted to extending them for multi-view clustering. Besides, many other multi-view clustering methods can be unified into the frameworks of these five methods. To promote further research and development of multi-view clustering, some popular and open datasets are summarized in two categories. Furthermore, several open issues that deserve more exploration are pointed out in the end.
Anatomical structures and needling method of the back-shu points BL18, BL20, and BL22 related to gastrointestinal organs: A PRISMA-compliant systematic review of acupoints and exploratory mechanism analysis

Background: Acupuncture treatment on back-shu points (BSPs) has received attention owing its ability to control the function of visceral organs. We aimed to conduct a systematic review to provide detailed information on the effectiveness and safety of BL18, BL20, and BL22 on the digestive system in terms of soft tissue and anatomical structure and assist in the appropriate application. Methods: Medline, Cochrane Library, EMBASE, OASIS, RISS, and CNKI were searched from their inception to July 2021. This systematic review included randomized controlled trials, controlled clinical trials, case series, and case reports that addressed anatomical structures or needling methods of BL18, BL20, and BL22. Results: In total, 115 articles were included from the 7 electronic databases. One hundred eight articles described the depth and method. A total of 96 articles described depth, 86 articles described the angle, and 74 articles described both. Seventy-nine articles described the target muscles and anatomical structure. Acupuncture on BSP is effective in gastrointestinal diseases because of compression of the spinal nerve, sympathetic nerve hyperactivity, and connection of the diaphragm. By reviewing each study’s acupuncture method and target muscles, we analyzed the angle and depth of the needle that effectively leads to therapeutic response. Conclusions: This study provides guidance on applying needles in terms of anatomical structures to yield therapeutic responses. However, few studies have assessed how to effectively stimulate BSP to trigger digestive effects and their mechanisms. Additional studies on the relationship between BSP and the digestive system are needed to use these acupoints for digestive diseases.
Integrating Outcome Research and Clinical Reasoning in Psychotherapy Planning

This article reviews the strengths and weaknesses of outcome research and clinical reasoning as bases of treatment planning and presents a synthesis in which these two types of information complement each other. The author proposes that therapy planning should begin with a review of the relevant outcome literature and also that divergence from research-based guidelines might be warranted under several conditions, including (a) when the client is demographically or culturally dissimilar to the study samples, (b) when assessment suggests a mismatch between the etiologies of the client’s disturbance and the processes addressed by empirically supported treatments, and (c) when use of such treatments is followed by a lack of progress that signals the advisability of midcourse correction.
The local economic development processes in low-income countries: The case of the metropolis of Chegutu in Zimbabwe

Local authorities are widely regarded as catalysts accelerating localised processes of economic development in industrialised countries but in low-income countries they are perceived as dysfunctional, inefficient and ineffective in meeting and addressing societal demands. This perception is not, however, grounded in empirical reality. As such, utilising the case of the metropolis of Chegutu a survey was designed to empirically explicate the economic processes supporting its economic development. The findings are useful to policy-makers, local government authorities and management scholars. The study's unique contribution lies in its examination of the processes of local economic development in a low-income country.
Nanobiosensors based on localized surface plasmon resonance for biomarker detection

Localized surface plasmon resonance (LSPR) is induced by incident light when it interacts with noblemetal nanoparticles that have smaller sizes than the wavelength of the incident light. Recently, LSPR-based nanobiosensors were developed as tools for highly sensitive, label-free, and flexible sensing techniques for the detection of biomolecular interactions. In this paper, we describe the basic principles of LSPR-based nanobiosensing techniques and LSPR sensor system for biomolecule sensing. We also discuss the challenges using LSPR nanobiosensors for detection of biomolecules as a biomarker.
Weak-lensing mass calibration of redMaPPer galaxy clusters in Dark Energy Survey Science Verification data

NASA through the Einstein Fellowship Program [PF5-160138]; DOE [DE-SC0015975, DE-AC02-98CH10886]; DAAD (Deutscher Akademischer Austauschdienst); Deutsche Forschungsgemeinschaft (DFG) [SFB-Transregio 33]; DFG cluster of excellence 'Origin and Structure of the Universe'; Sloan Foundation [FG-2016-6443]; U.S. Department of Energy; U.S. National Science Foundation; Ministry of Science and Education of Spain; Science and Technology Facilities Council of the United Kingdom; Higher Education Funding Council for England; National Center for Supercomputing Applications at the University of Illinois at Urbana-Champaign; Kavli Institute of Cosmological Physics at the University of Chicago; Center for Cosmology and Astro-Particle Physics at the Ohio State University; Mitchell Institute for Fundamental Physics and Astronomy at Texas AM Ministerio da Ciencia, Tecnologia e Inovacao; Deutsche Forschungsgemeinschaft; Argonne National Laboratory; University of California at Santa Cruz; University of Cambridge, Centro de Investigaciones Energeticas, Medioambientales y Tecnologicas-Madrid; University of Chicago, University College London; DES-Brazil Consortium; University of Edinburgh; Eidgenossische Technische Hochschule (ETH) Zurich, Fermi National Accelerator Laboratory; University of Illinois at Urbana-Champaign; Institut de Ciencies de l'Espai (IEEC/CSIC); Institut de Fisica d'Altes Energies, Lawrence Berkeley National Laboratory; Ludwig-Maximilians Universit sitat Munchen; University of Michigan; National Optical Astronomy Observatory; University of Nottingham; Ohio State University; University of Pennsylvania; University of Portsmouth, SLAC National Accelerator Laboratory, Stanford University; University of Sussex, Texas AM University; OzDES Membership Consortium; National Science Foundation [AST-1138766]; MINECO [AYA2012-39559, ESP2013-48274, FPA2013-47986]; Centro de Excelencia Severo Ochoa [SEV-2012-0234, SEV-2012-0249]; European Research Council under the European Union's Seventh Framework Programme (FP7); ERC [240672, 291329, 306478]; Excellence Cluster Universe
Staff Rotation: A Powerful Weapon Against Corruption?

The German federal government intends to introduce regular staff rotation as a precautionary measure against corruption in public administrations. To test the effectiveness of this instrument, we conduct an experiment using the bribery game by Abbink, Irlenbusch, and Renner (1999), in which pairs of potential bribers and public officials are randomly re-matched in every round. The data are compared to the analogous treatment with fixed pairs. The results provide strong evidence for the effectiveness of staff rotation in the experimental environment. The level of bribes as well as the frequency of inefficient decisions caused by bribery are reduced significantly.
Differential Performance across Discourse Types in MCI and Dementia

The purpose of this study was two-fold: to explore the effect of discourse type on the efficiency and effectiveness of expressive communication in individuals with MCI and early dementia; and to determine whether any discourse characteristics are predictive of cognitive performance. Seven adults (3 females; 4 males; age range: 59-79) representing several dementia diagnoses as well as MCI were administered six discourse tasks: a personal narrative, an advice question, single-paneled and multiple-paneled picture descriptions, a story retell, and a procedural discourse task. Hypotheses were formulated based on a presumed hierarchy of cognitive difficulty for the six discourse tasks. Discourse was analyzed for the occurrence of discourse-enhancing and discourse-impairing characteristics. Discourse-enhancing characteristics included mean length of utterance, verbal facility, the occurrence of modifiers, vocabulary diversity, and type-token ratio. Discourse-impairing characteristics included the occurrence of pronouns, repetitions, revisions, and incomplete utterances. The results of this study revealed significant differences between discourse tasks for all of the discourse-enhancing characteristics and for one discourse-impairing feature, the occurrence of pronouns. Post-hoc analyses revealed expected significant differences between measures for mean length of utterance, verbal facility, and pronouns, indicating decreased verbal facility and increased pronoun usage for measures that were cognitively more taxing. Conversely, unexpected significant differences between measures were revealed for discourse richness, including the occurrence of modifiers and vocabulary diversity, indicated increased discourse richness for the more cognitively demanding tasks. Correlational analyses revealed several significant relationships between discourse characteristics and cognitive status. However, differences were not consistent enough across measures to be able to reliably predict cognitive performance. This study resulted in several significant findings that speak to the sensitivity of discourse to shed light on cognitive factors such as episodic memory, working memory, semantic memory, attention, and higher level cognitive functions. However, significant differences between discourse types for discourse characteristics were not consistent enough to be generalizable. Limitations and suggestions for future research are discussed.
Decay form of the echo amplitude and echo phase of typical early/fast VLF event on 19.8 kHz signal

In this paper, the echo amplitude (M) and echo phase (o) of typical early/fast events on NWC (19.8 kHz) signal received at Suva, Fiji, are modelled to determine their form of recovery (decay). We applied logarithmic and exponential fitting formulas for M and o obtained using a simple theoretical model of VLF wave scattering from lightning-induced electron density perturbations in the lower ionosphere and found that they are highly logarithmic.
Effect of Aqueous Extract of Tigernut (Cyperus esculentus L.) on Sperm Parameters and Testosterone Level of Male Albino Rats

Tigernut is consumed by humans and livestock. It also has many medicinal uses. There is growing evidence of decline in human sperm count and quality. Hence, this study seeks to evaluate the effect of Aqueous Extract of Tigernut (AET) on testosterone level, weight of epididymes and testes, sperm count, semen pH, sperm motility, sperm viability and sperm head abnormalities in male rats as a model. The rats were divided into four groups of six rats each. The rats were treated with AET at 0.0, 0.6, 1.2 and 1.8 g kgG1 b.wt. dayG1, respectively for nine weeks. After which, the rats were sacrificed and assessed for the parameters. The AET had a dose-dependent effect on all the parameters. In conclusion, AET has the capability of increasing the weights of the testes and epididymes, sperm count, sperm quality and testosterone level. Hence, AET could be used as a possible fertility booster and to attenuate sperm toxicity.
THE SUSTAINED IMPACT OF THE HEAD START REDI INTERVENTION ON CHILDREN’S EXECUTIVE FUNCTION TRAJECTORIES THROUGH THIRD GRADE

This study examined the sustained effects of the Head Start REDI (Research-based, Developmentally-Informed) intervention, a randomized controlled preschool preventive intervention, on growth in children’s executive function (EF) skills from preschool through middle childhood. Forty-four classrooms were randomly assigned to receive Head Start REDI, which employed enhanced social-emotional and language/emergent literacy curriculum and strategies, or “usual practice” Head Start. The 356 4-year-old children (25% Aftrican American; 17% Latino; 54% girls) in those classrooms were followed for five years into third grade. Children’s EF skills were assessed annually. Two approaches were used to examine the sustained impact of REDI on growth in EF: latent growth curve modeling and latent class growth analysis. Results of latent growth curve modeling demonstrated the normative developmental process of EF over time, but did not find main or interaction (by initial EF status) effects of the intervention beyond normative development. Latent class growth analysis identified three EF trajectory classes at approximately high, moderate, and low levels of EF over time. Tests revealed significant intervention effects within the high and low trajectory classes, suggesting that of the children with high and low EF, those who were in REDI classrooms had significantly better EF outcomes than those who were not. This is the first study to document that preschool preventive interventions can have lasting impacts on EF growth in low-income children. These findings demonstrate how enriching Head Start with evidence-based curriculum and strategies can foster EF skill development, which is critical for children’s broader academic and social-emotional success.
Antioxidant Activity, Textural Properties and Storage Stability of Honey Fortified Biscuits

Honey is a supersaturated solution of sugars, which contains more than 180 other constituents like enzymes, amino acids and organic acids, carotenoids, Maillard reaction products, vitamins, minerals and polyphenols The objective of this study was to evaluate the effect of addition of honey on the sensorial attributes, total antioxidant capacity and textural properties of biscuits . The stability of the formulation during a one month storage period was also checked. To fulfill the objectives control and honey fortified biscuits were prepared in the laboratory. The biscuits were evaluated for their total phenols and total antioxidant capacity (from water and methanol extract of biscuits). Rheological properties from the biscuit dough and textural properties of control and honey fortified biscuits were also studied. Overall quality of control and 5% honey incorporated biscuits showed a better score as compared to 10 and 15% level of incorporation. The biscuits were stored for a period of one month and were analyzed for peroxide value on 15th and 30th day of storage period. The total phenolic content and total antioxidant activity of biscuits increased as the level of honey incorporation was increased. Methanolic extract showed higher total antioxidant activity as compared to water extract. The firmness of dough for control & experimental biscuits ranged from 8.68 – 19.55 kgf. Addition of 5gms honey produced significantly higher (P ≤.05) firmness as compared to control (12.16 kgf) & 15gms honey fortified biscuits (8.68 kgf). Addition of honey increased the adhesiveness from 0.12 (10gm honey biscuit) to 0.17kgf. mm (15gms honey biscuit). Honey incorporated samples showed a significant reduction in lipid peroxidation after 15th and 30th day of storage. Thus honey appears to be
Determination of Nutritional Status Via Food Frequency Consumption (FFQ) and Serum Proteins and Anemia Parameters in Multiple Sclerosis (MS) Patients

Objectives: The study was aimed to determine the nutritional status, serum proteins (total protein, albumin, prealbumin) and some anemia parameters (haemoglobin, iron, vitamin B 12, homocysteine) of the Multiple Sclerosis (MS) patients. Methods: It was conducted on 63 MS patients (41 female, 22 male) who have applied to Ankara Numune Education and Research Hospital, Department of Neurology, Turkey. Some anthropometric and biochemical measurements were taken from the study group. Nutritional status was assessed by food frequency consumption results. Results: The Relapsing/Remitting Multiple Sclerosis (RRMS) was mostly seen in both genders (90.5%). The mean age was found 34.9±8.59 (20-56) years in the study group. T he mean body mass index (BMI) was found as 25.2±4.86 kg/m 2 . While t he m ean albumin (p=0.021), prealbumin (p=0.005), homocystein (p=0.007), haemoglobin (p 0.05). There was no change in the consumption of egg, chicken, legumes, vegetable, fruit, margarine, butter and olive oil. Most of the two groups have consumed fish rarely before and after the diagnosis of MS. Conclusion: It was concluded that nutritional status of MS patients improved after diagnosis and serum proteins which also indicate that adequate and balanced nutrition were in desired levels.