Miracle-dz/UniFAR-FTUs huggingface dataset:
STABILITY ANALYSIS OF INSULATING PILLAR OF EXCAVATION OF CHAMBISHI COPPER MINE IN DEPTH

The appropriate size and stability of insulating pillar,which are transition stretch shifting from shallow excavation to deep mining,are very important for safe production of deep mine.According to the field engineering condition shifting from shallow excavation to deep mining,the appropriate size of insulating pillar is calculated and analyzed by using methods of limit span mechanism,empirical equation method and limit equilibrium method.The analysis result shows that for guaranteeing the insulating pillar stability the thickness of insulating pillar is 21 m.According to insulating pillar with thickness of 21 m,original design scheme is revised.FLAC3D is adopted to analyze the stability of revised design scheme,deformation and failure process of insulating pillar during caving.The numerical result shows that when mine is excavated 33 m high under insulating pillar,the insulating pillar will lose its strength and fail.Meanwhile,thickness of 28 m overburden layer is safe for non-hollow sublevel caving,which can guarantee the safety of personnel and equipment.It validates the revised insulating pillar thickness and conducts the production,which will supply the empirical method for the similar mine.
Prevalence of diseases and pathological conditions in young people under 45 years of age with abdominal obesity in Siberia

Aim. To study the prevalence of abdominal obesity in young people aged 25–44 years in Novosibirsk, as well as the prevalence of diseases and pathological conditions in individuals with abdominal obesity.Materials and methods. We conducted a cross-sectional, population-based study of the population of Novosibirsk aged 25–44 years. The screening examined 1,415 people, including 670 men and 745 women. For all individuals, we evaluated the presence of such conditions as abdominal obesity (AO), arterial hypertension (AH), increased body mass index (BMI), coronary heart disease (according to validated epidemiologic and functional criteria with ECG findings classified according to the Minnesota Code), diabetes mellitus (DM), reduced glomerular filtration rate (GFR), chronic bronchitis (CB), increased blood levels of total cholesterol (hypercholesterolemia) and lowdensity lipoprotein (LDL) cholesterol (hyper-LDL-cholesterolemia). Results. The prevalence of AO in the population of Novosibirsk aged 25–44 years was 42.4%: in men – 42.7%, in women – 42.1%. We found that AO had a significant direct effect on the development of AH (odds ratio (OR) = 2.550, 95% confidence interval (CI) 1.899–3.422, p = 0.0001), CB (OR = 1.830, CI 1.326–2.527, p = 0.0001), hypercholesterolemia (OR = 1.486, CI 1.193–1.851, p = 0.0001), hyper-LDL-cholesterolemia (OR = 1.527, CI 1.222–1.907, p = 0.0001) and a reverse effect on reduced GFR (OR = 0.603, CI 0.427–0.852, p = 0.004). In the male population under 45 years of age, AO had a significant direct effect on the development of AH, CB, hypercholesterolemia, and hyper-LDL-cholesterolemia. In the female population under the age of 45, AO had a significant direct effect on the development of DM, AH, CB, and hyper-LDL-cholesterolemia and a reverse effect on the reduced GFR development.Conclusion. Therefore, in the young Siberian population under 45 years of age, abdominal obesity is associated with the development of common diseases and pathological conditions.
Albumin-Fibrinogen ratio in rheumatoid arthritis and its relation to disease severity and radiographic progressive changes

Aim of the work: To evaluate the relationship between albumin-fibrinogen ratio (AFR) and radiographic changes in rheumatoid arthritis (RA) Patients and Methods: 50 rheumatoid patients and 30 control subjects were collected for the study, they were investigated for RF, Anti CCP, ESR, CR, fibrinogen and albumin. Also, they were subjected to x ray and MRI examination Results: There was significant increase in laboratory parameters and increase in albumin fibrinogen ratio in rheumatoid patients as compared to healthy control subjects. Also, there was positive correlation of the ratio with X ray and MRI score for synovitis and bone destruction Conclusion: AFR may be easily, rapidly detected and prognostically useful markers of ongoing inflammation and joint affection correspondingly to radiological findings. Albumin-Fibrinogen Ratio in rheumatoid arthritis and its relation to disease severity and radiographic progressive changes. O J Radio Med Img. 5: 01-06.
Do Overweight People Have Worse Cognitive Flexibility? Cues-Triggered Food Craving May Have a Greater Impact

Background: Overweight people have been revealed to have poor cognitive flexibility. Cognitive flexibility reflects proactive and reactive control abilities. However, the impairment had not been explicitly positioned at the cognitive stage. Therefore, this study provides increased support for impairment of cognitive flexibility due to overweight. Method: The study included 34 overweight and 35 normal-weight participants. They were required to complete the food and flower target AX-continuous performance test (AX–CPT), including the resting-state fMRI and cue-triggered food craving subscales. We compared the performance difference between the two tasks. Furthermore, we investigated whether the cue-triggered food cravings and the corresponding brain regions mediated the effect of overweight on the two control mechanisms. Result: Significant differences were found only in the food target AX-CPT task, where overweight participants performed worse. Cue-triggered food cravings mediated this relationship. Additionally, we found that the brain regions associated with cue-triggered food cravings (bilateral SFG) can completely mediate the relationship between BMI and the z-value of the fat mass index and sensitivity to proactive control. Conclusion: In the food target task, overweight participants performed worse in both control mechanisms. Moreover, we also revealed the potential mechanism by which being overweight might affect the two control mechanisms through cue-triggered food cravings.
The Requirements of Fog/Edge Computing-Based IoT Architecture

Fog/Edge computing architectures have become hot research issues with the recent development in the Internet of Things field. Although several studies have been published in this field, there is a need to focus more on exploring the analytical techniques used with these architectures. The problem that needs to be addressed is that ignoring IoT requirements when selecting the analytical techniques may affect the performance of Fog/Edge computing. Therefore, this paper first briefly discusses the IoT requirements for Fog/Edge computing. Then, the studies related to Fog/Edge computing are presented. Moreover, a comparative analysis is conducted in order to know if the proposed architecture considers the IoT requirements or not. This can be considered as a step toward designing the efficient architecture of IoT Fog/Edge computing. In addition, highlighting the IoT requirements that are not considered may encourage researchers to contribute more to this field.
Research on the Influence Mechanism of Consumers’ Purchase Intention of Electric Vehicles Based on Perceived Endorsement: A Case Study of Chinese Electric Vehicle Start-Ups

During the last decade, a number of electric vehicle start-ups have emerged in China. Although there have been quite a lot of studies on consumers’ purchase decision of electric vehicles, it is not common in the case of electric vehicle start-ups. This paper puts forward the concept of perceived endorsement and discusses the relationship among perceived benefit, perceived risk, range anxiety, attitude and consumers’ purchase intention and establishes a theoretical model of consumers’ purchase intention towards electric vehicles from start-ups. A structural equation model was used to test the research model and the hypotheses of the model. The results indicate that perceived endorsement has a significant positive influence on perceived benefit and attitude, which then affects consumers’ purchase intention, but range anxiety and perceived risk have no impact on purchase intention.
An Evaluation of the Pathogenic Potential, and the Antimicrobial Resistance, of Salmonella Strains Isolated from Mussels

Salmonella spp. and antimicrobial resistant microorganisms are two of the most important health issues worldwide. In the present study, strains naturally isolated from mussels harvested in Galicia (one of the main production areas in the world), were genetically characterized attending to the presence of virulence and antimicrobial resistance genes. Additionally, the antimicrobial profile was also determined phenotypically. Strains presenting several virulence genes were isolated but lacked all the antimicrobial resistance genes analyzed. The fact that some of these strains presented multidrug resistance, highlighted the possibility of bearing different genes than those analyzed, or resistance based on completely different mechanisms. The current study highlights the importance of constant surveillance in order to improve the safety of foods.
CFD Research on the Hydrodynamic Performance of Submarine Sailing near the Free Surface with Long-Crested Waves

The simulations of submarine sailing near the free surface with long-crested waves have been conducted in this study using an in-house viscous URANS solver with an overset grid approach. First, the verification and validation procedures were performed to evaluate the reliability, with the results showing that the generation of irregular waves is adequately accurate and the results of total resistance are in good agreement with EFD. Next, three different submerged depths ranging from 1.1D to 3.3D were selected and the corresponding conditions of submarine sailing near calm water were simulated, the results of which were then compared with each other to investigate the influence of irregular waves and submerged depths. The simulations of the model near calm water at different submerged depths demonstrated that the free surface will cause increasing resistance, lift, and bow-up moments of the model, and this influence decreases dramatically with greater submerged depths. The results of the irregular wave simulations showed that irregular waves cause considerable fluctuations of hydrodynamic force and moments, and that this influence remains even at a deeper submerged depth, which can complicate the control strategies of the submarine. The response spectrum of hydrodynamic forces and moments showed slight amplitudes in the high-frequency region, and the model showed less sensitivity to high-frequency excitations.
DNA barcoding and morphological identification of spiny lobsters in South Korean waters: a new record of Panulirus longipes and Panulirus homarus homarus

To date, 19 species of spiny lobsters from the genus Panulirus have been discovered, of which only P. japonicus, P. penicilatus, P. stimpsoni, and P. versicolor have been documented in South Korean waters. In this study, we aimed to identify and update the current list of spiny lobster species that inhabit South Korean waters based on the morphological features and the phylogenetic profile of cytochrome oxidase I (COI) of mitochondrial DNA (mtDNA). Spiny lobsters were collected from the southern and eastern coasts of Jeju Island, South Korea. Phylogenetic analyses were performed using neighbor-joining (NJ), maximum likelihood (ML), and Bayesian inference (BI) methods. The ML tree was used to determine the spiny lobster lineages, thereby clustering the 17 specimens collected in this study into clades A, B, C, and D, which were reciprocally monophyletic with P. japonicus, P. homarus homarus, P. longipes, and P. stimpsoni, respectively. These clades were also supported by morphological examinations. Interestingly, morphological variations, including the connected pleural and transverse groove at the third abdominal somite, were observed in four specimens that were genetically confirmed as P. japonicus. This finding is novel within the P. japonicus taxonomical reports. Additionally, this study updates the documentation of spiny lobsters inhabiting South Korean waters as P. longipes and P. homarus homarus were recorded for the first time in this region.
Predicting intention and maintenance of breastfeeding up to 2-years after birth in primiparous and multiparous women

Abstract Objectives Breastfeeding up to 2-years has been associated with short and long-term health benefits for both newborns and mothers. However, few women breastfeed up to 2-years after birth. This study extends previous research on the theory of planned behaviour (TPB) examining the predictors of intention and maintenance of breastfeeding up to 2-years in both primiparous and multiparous women. Design 155 pregnant women participated in this longitudinal study. Methods Expectant mothers completed a questionnaire and then 2-years after the child’s birth were asked to report breastfeeding behaviour. Interactions among parity and TPB constructs were examined. Results Attitudes, descriptive and injunctive norms, and perceived behavioural control (PBC) explained 58% of the variance in mothers’ intention to breastfeed. Attitudes were the strongest predictor, followed by PBC, descriptive norms and parity. A significant interaction was found between parity and PBC, showing that PBC was only a significant predictor of intention to breastfeed at 2-years in multiparous women. Intentions predicted breastfeeding behaviour at 2-years. Conclusion Promoting intentions may be a useful way to increase breastfeeding duration to 2-years and targeting attitudes and norms may be one way to increase intentions. Further, targeting PBC may also be useful to increase intentions, but only in multiparous women.
Durability Study of Large-scale Reinforced Concrete Piled Wharf

In combination with the large-scale reinforced concrete piled wharf constructed during the past 20 years in Chiwan Port and according to the results of real survey, investigation and scientific research both in China and abroad, suggestions on durability of piled wharf already built and to be built are put forward. 
Development of Cobalt-Binding Peptide Chelate from Human Serum Albumin: Cobalt-Binding Properties and Stability

Radioactive isotopes are used as drugs or contrast agents in the medical field after being conjugated with chelates such as DOTA, NOTA, DTPA, TETA, CyDTA, TRITA, and DPDP. The N-terminal sequence of human serum albumin (HSA) is known as a metal binding site, such as for Co2+, Cu2+, and Ni2+. For this study, we designed and synthesized wAlb12 peptide from the N-terminal region of HSA, which can bind to cobalt, to develop a peptide-based chelate. The wAlb12 with a random coil structure tightly binds to the Co(II) ion. Moreover, the binding property of wAlb12 toward Co(II) was confirmed using various spectroscopic experiments. To identify the binding site of wAlb12, the analogs were synthesized by alanine scanning mutagenesis. Among them, H3A and Ac-wAlb12 did not bind to Co(II). The analysis of the binding regions confirmed that the His3 and α-amino group of the N-terminal region are important for Co(II) binding. The wAlb12 bound to Co(II) with Kd of 75 μM determined by isothermal titration calorimetry when analyzed by a single-site binding model. For the use of wAlb12 as a chelate in humans, its cytotoxicity and stability were investigated. Trypsin stability showed that the wAlb12 − Co(II) complex was more stable than wAlb12 alone. Furthermore, the cell viability analysis showed wAlb12 and wAlb12 + Co(II) to be non-toxic to the Raw 264.7 and HEK 293T cell lines. Therefore, a hot radioactive isotope such as cobalt-57 will have the same effect as a stable isotope cobalt. Accordingly, we expect wAlb12 to be used as a peptide chelate that binds with radioactive isotopes.
Critical care for concomitant severe traumatic brain injury and acute spinal cord injury in the polytrauma patient: illustrative case

BACKGROUND The occurrence of traumatic brain injury with spinal cord injury (SCI) in polytrauma patients is associated with significant morbidity. Clinicians face challenges from a decision-making and rehabilitative perspective. Management is complex and understudied. Treatment should be systematic beginning at the scene, focusing on airway resuscitation and hemodynamic stabilization, immobilization, and timely transport. Early operative interventions should be provided, followed by minimizing secondary pathophysiology. The authors present a case to delineate decision-making in the treatment of combined cranial and spinal trauma. OBSERVATIONS A 19-year-old man presented as a level I trauma patient after falling 30 feet as the result of scaffolding collapse. The patient was unresponsive and was intubated; he had an initial Glasgow Coma Scale score of 4. Computed tomography revealed multicompartmental bleeding and herniation, for which supra- and infratentorial decompressive craniectomies were performed. The patient also suffered from thoracic SCI that resulted in complete paraplegia. Multimodality monitoring was used. After stabilization and lengthy rehabilitation, the patient obtained significant functional improvement. LESSONS The approach to initial management of concomitant head and spine trauma is to establish intracranial stability followed by intraspinal stability. Patients can make considerable recovery, particularly younger patients, who are more likely to benefit from early aggressive interventions and medical treatment.
Study on Stability Performance of Friction Stir Welded Stiffened Panel under Uniaxial Compress Load

Local critical buckling stress of friction stir welded stiffened panel is calculated by semi-empirical formula.In addition,finite element software ABAQUS is applied to analyze the buckling behavior of the structure.According to the calculation results,axial compress test on stiffened panel specimens is conducted to obtain the stability performance and carrying capacity of the structure.The effect of boundary condition of unloaded edges is considered.It is found that boundary condition of unloaded edges has less effect on the carrying capacity than critical buckling load of the specimens.The experiment results indicate that the structure studied has a certain post-buckling carrying capacity and the finite element method is capable to analysis the stability of the structure,which offers a referenced means for the optimization design and engineering application of the structure.
Interspecies transfer of syntenic RAMOSA1 orthologs and promoter cis sequences impacts maize inflorescence architecture

Grass inflorescences support floral structures that each bear a single grain, where variation in branch architecture directly impacts yield. The maize RAMOSA1 (ZmRA1) transcription factor acts as a key regulator of inflorescence development by imposing branch meristem determinacy. Here, we show RA1 transcripts accumulate in boundary domains adjacent to spikelet meristems in Sorghum bicolor (Sb) and Setaria viridis (Sv) inflorescences similar as in the developing maize tassel and ear. To evaluate functional conservation of syntenic RA1 orthologs and promoter cis sequences in maize, sorghum and setaria, we utilized interspecies gene transfer and assayed genetic complementation in a common inbred background by quantifying recovery of normal branching in highly ramified ra1-R mutants. A ZmRA1 transgene that includes endogenous upstream and downstream flanking sequences recovered normal tassel and ear branching in ra1-R. Interspecies expression of two transgene variants of the SbRA1 locus, modeled as the entire endogenous tandem duplication or just the non-frameshifted downstream copy, complemented ra1-R branching defects and induced novel fasciation and branch patterns. The SvRA1 locus lacks conserved, upstream noncoding cis sequences found in maize and sorghum; interspecies expression of an SvRA1 transgene did not or only partially recovered normal inflorescence forms. Driving expression of the SvRA1 coding region by the ZmRA1 upstream region, however, recovered normal inflorescence morphology in ra1-R. These data leveraging interspecies gene transfer suggest that cis-encoded temporal regulation of RA1 expression is a key factor in modulating branch meristem determinacy that ultimately impacts grass inflorescence architecture.
Impact of Electrospun Piezoelectric Core–Shell PVDFhfp/PDMS Mesh on Tenogenic and Inflammatory Gene Expression in Human Adipose-Derived Stem Cells: Comparison of Static Cultivation with Uniaxial Cyclic Tensile Stretching

Specific microenvironments can trigger stem cell tenogenic differentiation, such as specific substrates or dynamic cell cultivation. Electrospun meshes composed by core–shell fibers (random or aligned; PDMS core; piezoelectric PVDFhfp shell) were fabricated by coaxial electrospinning. Elastic modulus and residual strain were assessed. Human ASCs were seeded on such scaffolds either under static conditions for 1 week or with subsequent 10% dynamic stretching for 10,800 cycles (1 Hz, 3 h), assessing load elongation curves in a Bose® bioreactor system. Gene expression for tenogenic expression, extracellular matrix, remodeling, pro-fibrotic and inflammatory marker genes were assessed (PCR). For cell-seeded meshes, the E modulus increased from 14 ± 3.8 MPa to 31 ± 17 MPa within 3 h, which was not observed for cell-free meshes. Random fibers resulted in higher tenogenic commitment than aligned fibers. Dynamic cultivation significantly enhanced pro-inflammatory markers. Compared to ASCs in culture flasks, ASCs on random meshes under static cultivation showed a significant upregulation of Mohawk, Tenascin-C and Tenomodulin. The tenogenic commitment expressed by human ASCs in contact with random PVDFhfp/PDMS paves the way for using this novel highly elastic material as an implant to be wrapped around a lacerated tendon, envisioned as a functional anti-adhesion membrane.
Fast-track cache: a huge racetrack memory L1 data cache

First-level (L1) caches have been traditionally implemented with Static Random-Access Memory (SRAM) technology, since it is the fastest memory technology, and L1 caches call for tight timing constraints in the processor pipeline. However, one of the main downsides of SRAM is its low density, which prevents L1 caches to improve their storage capacity beyond a few tens of KB. On the other hand, the recent Domain Wall Memory (DWM) technology overcomes such a constraint by arranging multiple bits in a magnetic racetrack, and sharing a header to access those bits. Accessing a bit requires a shift operation to align the target bit under the header. Such shifts increase the final access latency, which is the main reason why DWM has been mostly used to implement slow last-level caches. This paper proposes a novel DWM-based L1 cache data array design, namely Fast-Track Cache (FTC), that allows L1 caches with bigger storage capacities while reducing the shift overhead thanks to an enhanced exploitation of spatial and temporal localities. Experimental results show that most FTC accesses do not require shifts. As a consequence, and due to its larger capacity, FTC improves the processor performance on average by 15% over a conventional SRAM memory subsystem and the state-of-the-art TapeCache architecture based on DWM. At the same time, energy savings are improved on average by 34% over the conventional design.