Miracle-dz/UniFAR-FTUs huggingface dataset:
Community as Doctor: New Perspectives on a Therapeutic Community

Balint and Balint Psychotherapeutic Techniques in Medicine (1961) Hb: 0-415-26457-X Brown and Harris Social Origins of Depression (1978) Hb: 0-415-26458-8 Caplan An Approach to Community Mental Health (1961) Hb: 0-415-26459-6 Clark Administrative Therapy (1964) Hb: 0-415-26460-X Rapoport Community as a Doctor (1960) Hb: 0-415-26461-8 Siirala Medicine in Metamorphosis (1969) Hb: 0-415-26462-6
Molecular Detection, Phylogenetic Analysis, and Genetic Diversity of Theileria annulata, Babesia bigemina, and Anaplasma marginale in Cattle in Three Districts of Egypt

Under the poor hygienic conditions, tick-borne pathogens cause severe economic losses to the cattle industry. The current study investigated the presence of Theileria annulata, Babesia bigemina, and Anaplasma marginale, the most relevant tick-borne pathogens in cattle, in 3 provinces of Egypt utilizing species-specific PCR assays. PCR was conducted, on bovine blood specimens, using primers targeting the T. annulata merozoite–piroplasm surface antigen (Tams1, 768 bp), A. marginale major surface protein-1b gene (msp1b, 265 bp), and B. bigemina small subunit ribosomal RNA gene (SSrRNA, 543 bp). PCR findings revealed overall prevalences of T. annulata, B. bigemina, and A. marginale as 22.0% (33/150), 19.33% (29/150), and 10.6% (16/150), respectively. The co-infection with two or three pathogens was detected in 20.0% (30/150) of examined specimens. Sequence analyses indicated that T. annulata and A. marginale varied from those of corresponding GenBank sequences revealing percent identities ranging from 90.68 to 97.75% and from 94.98 to 98.63%, respectively. On the other hand, the obtained B. bigemina sequences showed a high similarity with those previously reported in GenBank with a percent identity ranging from 98.85 to 100%. T. annulata was the most prevalent tick-borne pathogen in examined bovine specimens. The genetic diversity of markers used for identification of T. annulata and A. marginale should be highly considered.
Literature on safety module for vehicular driver assistance

Automatic Guided Vehicle (AGV) nothing but vehicle guideline provided by capturing images of the road. In this paper we have design an embedded surveillance and safety systems. The system also provides full driver assistance by determining the distance between two vehicles. The lane departure is an improved technique in which lane boundaries are analyzed continuously and will also report to the user as soon as vehicle is try move outside the lane or road. So this system not only helps to provide safety but also helps in reducing the cost which is further considered to be most important factor.
MetaBridge: An Integrative Multi‐Omics Tool for Metabolite‐Enzyme Mapping

MetaBridge is a web‐based tool designed to facilitate the integration of metabolomics with other “omics” data types such as transcriptomics and proteomics. It uses data from the MetaCyc metabolic pathway database and the Kyoto Encyclopedia of Genes and Genomes (KEGG) to map metabolite compounds to directly interacting upstream or downstream enzymes in enzymatic reactions and metabolic pathways. The resulting list of enzymes can then be integrated with transcriptomics or proteomics data via protein‐protein interaction networks to perform integrative multi‐omics analyses. MetaBridge was developed to be intuitive and easy to use, requiring little to no prior computational experience. The protocols described here detail all steps involved in the use of MetaBridge, from preparing input data and performing metabolite mapping to utilizing the results to build a protein‐protein interaction network. © 2020 by John Wiley & Sons, Inc.
Characterization and Antimicrobial Sensitivity of Staphylococcus aureus Isolates from Subclinical Bovine Mastitis

Received: 2013-04-12 Revised: 2013-06-25 Accepted: 2013-06-26 Pathogenic Staphylococcus aureus was isolated from the cases of subclinical mastitis in lactating cows. A total of 214 quarter milk samples were screened of which, 110 (51.40%) samples were found positive for subclinical mastitis (SCM) using California Mastitis test (CMT). Isolation of Staph. aureus was attempted in 68 samples, comprising 52 distinct and 16 strong CMT positive samples. All 68 samples yielded Staph. aureus. All the isolates were catalase positive while 54 (79.41%) and 56 (82.35%) isolates showed positive slide and tube coagulase test, respectively. On sugar fermentation all the isolates were positive for mannitol fermentation, while 59 (86.76%) and 53 (77.94%) isolates fermented glucose and lactose. On sheep blood agar, 48 (17.58%) isolates showed β-haemolysis and 59 (86.76%) samples were positive for nitrate reduction test. Coa gene was detected in all the Staph. aureus while 22 (32.35%) isolates revealed Spa (X region) gene. All the isolates were sensitive to Cefotaxime while highest number of isolates 63 (92.64%), were found resistant to ampicillin, followed by 20 (29.41%) for tetracycline, 17 (25.00%) for ofloxacin, 11 (16.17%) for lincomycin and 09 (13.23%) for ciprofloxacin, respectively. All copyrights reserved to Nexus® academic publishers
“Cropping School”-An alternative to advisory services in Brandenburg, Germany?

In Brandenburg, unlike in other federal states of Germany, neither public advisory services are available nor organic field trials are conducted. Farmers are largely left alone with the challenge to develop individual cropping solutions in addition to their daily operative business. Therefore, the new concept of a “Cropping School” based on Farmer Field Schools and Stable Schools has been developed and will be piloted in the north-east of Brandenburg, Germany. The main goals of the Cropping School are to empower farmers to take action for improving their cropping system and to develop a practice based approach as an alternative to advisory services
THE DETERMINANTS OF TAX ENFORCEMENT ALONG TIME: THE ROLE OF CENTRAL AND REGIONAL TAX AUTHORITIES

Tax evasion still represents a major concern in any developed and developing country and little is understood about the factors that determine the real tax base that taxpayers report to the government and which is the optimal way to enforce the existing tax code. In this paper we aim at analyzing the determinants of the productivity of tax enforcement and thus indirectly of the tax compliance. Our preliminary and partial results are congruent with standard theory; in particular we find that the size of the tax agency positively impacts the productivity on voluntary compliance and that tax enforcement policies are pro-cyclical: the effectiveness/productivity of tax enforcement is higher in times of economic growth with respect to times of economic decay.
Electroporation : New strategy to improve the drug uptake and overcome the tumour resistance

Electrochemotherapy is an innovative therapeutic strategy to overcome multidrug resistance (MDR) phenomenon of several neoplasms. New anticancer treatment combines the administration of a chemotherapeutic agent with the application of electric pulses (electroporation, EP) having appropriate waveforms to increase drug uptake. Its efficacy as adjuvant therapy has been already demonstrated in the veterinary patients, in combination with several anticancer agents resulting in enhanced cytotoxicity. The main goal of our project is to increase the effectiveness of doxorubicin (DOX) on MDR human colon adenocarcinoma cell line (LoVo DX) and mitomycin C (MMC) on two human breast adenocarcinoma cell lines (MCF-7 WT and MCF-7 DX), by using trains of biphasic pulses. The in vitro experiments of the combined treatment (EP plus DOX) showed the enhancement of DOX accumulation and nuclear distribution on LoVo DX cell suspension, evaluated by flow cytometry and confocal microscopy, respectively. Moreover, evident morphological changes were observed by scanning electron microscopy. MTT assay showed that MCF-7 cells treated with EP alone showed the same cell viability as the control; this proves that electrical impulses alter only the membrane permeability favouring drug uptake without inducing a cytotoxic effect on tumour cells. Cell viability assay showed a 20% reduction after the combined EP plus MMC treatment. Further studies will be carried out to confirm the cytotoxic damage and assess the role of electrochemotherapy in the pharmacological resistance phenomenon.
Septic cardiomyopathy: evidence for a reduced force-generating capacity of human atrial myocardium in acute infective endocarditis

Abstract Background: This study analyzes the myocardial force-generating capacity in infective endocarditis (IE) using an experimental model of isolated human atrial myocardium. In vivo, it is difficult to decide whether or not alterations in myocardial contractile behavior are due to secondary effects associated with infection such as an altered heart rate, alterations of preload and afterload resulting from valvular defects, and altered humoral processes. Our in vitro model using isolated human myocardium, in contrast, guarantees exactly defined experimental conditions with respect to preload, afterload, and contraction frequency, thus not only preventing confounding by in vivo determinants of contractility but also excluding effects of other factors associated with sepsis, hemodynamics, humoral influences, temperature, and medical treatment. Methods: We analyzed right atrial trabeculae (diameter 0.3–0.5 mm, initial length 5 mm) from 32 patients undergoing aortic and/or mitral valve replacement for acute valve incompetence caused by IE and 65 controls receiving aortic and/or mitral valve replacement for nonendocarditic valve incompetence. Isometric force amplitudes and passive resting force values measured at optimal length in the two groups were compared using Student’s t-test. Results: There were no significant differences between the groups in terms of the passive resting force. The isometric force amplitude in the endocarditis group, however, was significantly lower than in the nonendocarditis group (p=0.001). In the endocarditis group, the calculated active force, defined as the isometric force amplitude minus the resting force, was significantly lower (p<0.0001) and the resting force/active force ratio was significantly higher (p<0.0001). Using linear regression to describe the function between resting force and active force, we identified a significant difference in slope (p<0.0001), with lower values found in the endocarditis group. Conclusion: Our data suggest that the force-generating capacity of atrial myocardium is significantly reduced in patients with IE. In these patients, an elevated resting force is required to achieve a given force amplitude. It remains unclear, however, whether this is due to calcium desensitization of the contractile apparatus, presence of myocardial edema, fibrotic remodeling, disruption of contractile units, or other mechanisms.
A TEST OF SHARKEY AND SINGELIS’ (1995) MODEL / G. H. J. KRUGER A TEST OF SHARKEY AND SINGELIS’ (1995) MODEL OF SELF-CONSTRUAL AND EMBARRASSABILITY: SITUATIONAL VERSUS DISPOSITIONAL FACTORS1

—Sharkey and Singelis (1995) tested a model of embarrassment focusing on strength of independent self-construal, sensitivity to evaluation, and strength of interdependent self-construal. Their findings indicated social anxiety and self-construal explained 28% of the variance in embarrassability. Separately, social anxiety contributed 5.8%, with independent and interdependent self-construal explaining 6.6 and 5.2%, respectively, thus supporting the model. Sharkey and Singelis used Modigiliani’s (1968) Embarrassability Scale, which focuses on embarrassing situations. The current study repeated the analysis but measured embarrassability as a disposition on a sample of Black African (59.8%), Colored (6.1%), Asian/Indian (5.9%), and White (28.2%) first-year psychology students (139 men, 485 women) between 18 and 51 years old (M = 19.5, SD = 2.9). The three constructs together explained about 47% of dispositional embarrassability. Social anxiety explained 25% of the variance, when controlling for independent and interdependent self-construal. Sharkey and Singelis’ model may be more applicable to the explanation of situational embarrassability than dispositional embarrassability.
Total Synthesis of Asparenydiol by Two Sonogashira Cross-Coupling Reactions Promoted by Supported Pd and Cu Catalysts

Abstract Asparenydiol, which is an important natural compound with potential pharmacological activities, was synthesized through two Sonogashira cross-coupling reactions catalyzed by supported Pd and Cu catalysts and by a Mitsunobu etherification. The optimization of the Sonogashira couplings allowed the use of catalysts supported on different matrices with good results in terms of catalytic efficiency and yields.
An Optimal Detection of Polyp and Ulcer in WCE Images using Fast BEMD with DLac Analysis”

— the main contribution of this paper is the presentation of a novel tool for WCE image analysis and classification by exploiting color-texture features. The proposed scheme has based on the ingenious combination of BEEMD and DLac, applied on the green/red component of WCE images in order to identify ulcerations. BEEMD, apart from an adaptive image denoising tool, was exploited to reveal the intrinsic components (IMFs) of the images in order to achieve data driven, Coefficient of Variance (CV), boost the distinctness between polyp and ulcer regions and facilitate DLac analysis to extract efficient texture characteristics. Optimum IMF selection based on the structure patterns of IMFs disclosed by DLac. The optimum IMFs are used to reconstruct a new refined image. The proposed approach has evaluated on selected WCE images, captured from patients, depicting ulcer and polyp tissue. The optimum image components (IMFs) that contain the majority of texture information include IMFs 5 and 8. Individual IMFs score up to 85.8% classification accuracy, while their exploitation as a group enhances the detection rate up to 94.3% for ulcer and polyp tissue.
Speech/Music Classification using RBFNN

: Audio classification serves as the fundamental step towards the rapid growth in audio data volume. Automatic audio classification is very useful in audio indexing; content based audio retrieval and online audio distribution. The accuracy of the classification relies on the strength of the features and classification scheme. In this work a speech/music discrimination system is developed which utilizes the Discrete Wavelet Transform (DWT) as the acoustic feature. This paper analyses neural networks and their precision when they both stumble upon same targets in similar category. The analysis is done on radial basis function neural network (RBFNN) then a conclusion is formed on the basis of their performance and efficiency.
DIPLOME D'ETAT DE DOCTEUR EN PHARMACIE

HAL is a multi-disciplinary open access archive for the deposit and dissemination of scientific research documents, whether they are published or not. The documents may come from teaching and research institutions in France or abroad, or from public or private research centers. L’archive ouverte pluridisciplinaire HAL, est destinée au dépôt et à la diffusion de documents scientifiques de niveau recherche, publiés ou non, émanant des établissements d’enseignement et de recherche français ou étrangers, des laboratoires publics ou privés. La substitution de l’héroïne par la morphine Rémi Mengarduque
“NOTHING IS MORE POWERFUL THAN AN IDEA WHOSE TIME HAS COME ”

Crypto-currencies constitute an asset class characterised by high returns, high volatilities, and low correlations. Rational investment decisions in such a setting rely on portfolio-optimisation theory. At the same time, cryptocurrency markets are not yet fully integrated with standard financial markets. Therefore, employing standard models of portfolio management can fail to incorporate critical information, unnecessarily loading up on unpriced risk, to capture priced return regularities, foregoing desired remunerated exposure, or to acknowledge the institutional environment, incurring gratuitously transaction costs. F5 provides an optimised investment strategy based on the main tenets of the state-of-the-art academic finance literature, and designed specifically for the setting of today’s crypto-currency markets.
OP-ICBJ170056 159..167

Synopsis Species distribution models typically use correlative approaches that characterize the species–environment relationship using occurrence or abundance data for a single species. However, species distributions are determined by both abiotic conditions and biotic interactions with other species in the community. Therefore, climate change is expected to impact species through direct effects on their physiology and indirect effects propagated through their resources, predators, competitors, or mutualists. Furthermore, the sign and strength of species interactions can change according to abiotic conditions, resulting in context-dependent species interactions that may change across space or with climate change. Here, we incorporated the context dependency of species interactions into a dynamic species distribution model. We developed a multi-species model that uses a time-series of observational survey data to evaluate how abiotic conditions and species interactions affect the dynamics of three rocky intertidal species. The model further distinguishes between the direct effects of abiotic conditions on abundance and the indirect effects propagated through interactions with other species. We apply the model to keystone predation by the sea star Pisaster ochraceus on the mussel Mytilus californianus and the barnacle Balanus glandula in the rocky intertidal zone of the Pacific coast, USA. Our method indicated that biotic interactions between P. ochraceus and B. glandula affected B. glandula dynamics across >1000 km of coastline. Consistent with patterns from keystone predation, the growth rate of B. glandula varied according to the abundance of P. ochraceus in the previous year. The data and the model did not indicate that the strength of keystone predation by P. ochraceus varied with a mean annual upwelling index. Balanus glandula cover increased following years with high phytoplankton abundance measured as mean annual chlorophyll-a. M. californianus exhibited the same pattern to a lesser degree, although this pattern was not significant. This work bridges the disciplines of biogeography and community ecology to develop tools to better understand the direct and indirect effects of abiotic conditions on ecological communities.
A REVIEW ON MULTIMODAL DEEP LEARNING METHOD FOR ANDROID MALWARE DETECTION

: With the global use of smart phones, the number of malware has been increasing rapidly. Among all the smart devices, Android devices are the most targeted devices by malware due to their high popularity. This paper set forth a framework for Android malware detection and prevention. The various kinds of features are used by the framework to reflect the various properties of the Android applications from different aspects , and the features are refined using similar based or existence based of feature extraction method for feature representation of malware detection and prevention. For this a multimodal deep learning method is introduced and to be used as a malware detection and prevention model for Androids. With this detection model, it will be possible to gain the maximum benefits of multiple features. To estimate performance, various experiments are carried out and the accuracy of the model is the deep neural network models. Further the framework is evaluated in various types of aspects such as efficiency of model in updates usefulness of the diverse features and the representation of the feature method.
USE OF SEWAGE WASTEWATER IN AGRICULTURE AND ITS EFFECTS ON SOIL MACROFAUNA

Wastewater is a principal source of irrigation in developing countries. In world overall, more than 20 million hectares are being irrigated with this wastewater (Dreschsel et al., 2002). Presently, great amount of the unprocessed sewage wastewater is being released into the natural environment and into other water bodies; also, farmers use this sewage waste water for irrigation purpose UNESCO 2003). Though, there are many environmental and health issues regarding wastewater, but on the other hand, it is a cheap source and contains many nutrients like phosphorus and nitrogen etc. that stand helpful for the enhanced crop production (Scott et al., 2004; IWMI and Rauf, 2002). It also includes many inorganic pollutants such as heavy metals with significance tendency of absorption by soil colloids and subsequently these metals are released into the soil components (Bruins et al., 2000). Major sources of the wastewater are industries, households, commercial premises and municipal drains. This water contains undesired organic compounds, heavy metals and hazardous chemicals etc. (Cornish et al., 1999), that eventually causes soil degradation and adversely affects the environment and ecosystem globally (Wei and Chen, 2001; Chen et al., 2012; Li et al., 2013). The organisms require small quantities of some heavy metals such as Cu, Co, Fe, Mn, Ni and Zn. Though, excessive quantities of these elements can become detrimental to organisms. Furthermore, some heavy metals such as Pb, Cd, Hg, and As, do not have any valuable effect on soil organisms and therefore are considered as the main threats, being harmful, to both animals and plants (Bruins et al., 2000; Chibuike and Obiora, 2014). However, impact of sewerage sludge on soil veracity is not completely investigated yet (Kandeler et al., 1996). Bioaccumulation takes place when various metal substances are introduced to food chains of soil ecosystem via groundwater and becomes harmful if heavy metals concentrations exceed permissible limits in the prevailing soil (Ettler et al., 2004; Rodella and Chiou, 2009). Soil contamination may alter soil ecosystem performance; both quantitatively and qualitatively by imposing inappropriate decomposition, N-mineralization and carbon, nitrogen, sulphur and phosphorus cycling (Shah et al., 2005). Soil community generally includes a great number of species that participate in a variety of ecosystem functions e.g. development of the soil structure dynamics and organic matter turn-over etc. (Giller, 1996; Barros et al., 2004). They may be small (snails, ants); large (rodents) and they exert effects on soil physical properties directly or indirectly as well as biological processes, important for animal and plant life (Fackenath and Lalljee, 1999). The role of soil macrofauna largely depends upon their abundance and soil health (Lavelle, 1997). Amongst the invertebrates, macrofauna is of Pak. J. Agri. Sci., Vol. 5X(X), xxx-xxx; 20xx ISSN (Print) 0552-9034, ISSN (Online) 2076-0906 DOI: 10.21162/PAKJAS/20.9485 http://www.pakjas. com.pk
Biosynthetic Silver Nanoparticles- Current Trends and Future Scope: An Overview

Nanoparticle (NPs) biosynthetic discipline is still under development and recognized to have a big impact on numerous manufactures for a long time. Now a days silver nanoparticles (AgNPs) is a thrust field for researchers in context to its antimicrobial property. There are three methods to synthesize AgNPs, which are charcaterized to be physically, chemically and biologically active. Physical and chemical techniques for the production of NPs are expensive, toxic, and non-ecofriendly. To overcome these problems, researchers have brought into practice the precise green routes. Now a days nanobiotechnological method is becoming popular because of its safe, non-toxic, cheap and ecofriendly nature using plants and microorganisms. Nanobiotechnology so far has been flourishing to produce AgNPs, which have rewarding applications in industry, health and medicinal sciences specifically due to their antimicrobial characteristics. This overview covers current trends of biosynthesis of AgNPs, and expression of their salient antimicrobial activity concomitant with their future biotechnological scope.