Miracle-dz/UniFAR-FTUs huggingface dataset:
a Crown-of-Thorns Starfish predator Running title : Giant triton snail neuropeptides

Neuropeptides represent a diverse class of signaling molecules originating from neural tissues. These chemical modulators orchestrate complex physiological events including those associated with growth and reproduction. De novo transcriptome sequencing of a cerebral ganglion library of the endangered giant triton snail (Charonia tritonis) was undertaken in an effort to identify key neuropeptides that control or influence its physiology. The giant triton snail is considered a primary predator of the corallivore Acanthaster planci (Crown-ofThorns Starfish) that is responsible for a significant loss in coral cover on reefs in the IndoPacific. The transcriptome library was assembled into contigs, and then bioinformatic
Supplemental material

kICS analysis A modification of kICS analysis was used to study CFTR membrane dynamics (Kolin et al., 2006; Pandzic, 2013; Abu-Arish et al., 2015). Briefly, the k-space temporal correlation function Φ( k .; τ) was obtained by calculating the temporal correlation function of the k-space domain image series, which is first calculated using a 2-D spatial Fourier transform of each image in the original microscopy time series
Low-Temperature Al-Al Thermocompression Bonding with Sn Oxidation Protect Layer for Wafer-Level Hermetic Sealing

SUMMARY This paper describes hermetic seal wafer bonding using Al covered with thin Sn as an antioxidation layer. The bonding temperature is below 400 °C, which is the maximum temperature of CMOS-LSI backend process. Gas tightness over 3000 h at room temperature and sealing stability through heat treatment under a typical reflow condition of 260 °C for 10 min were confirmed for samples bonded at 370 °C and 380 °C. A key for successful hermetic seal bonding is relatively high bonding pressure and stress concentration on sealing frames as narrow as several micrometers. The results of SEM and EDX analysis suggested that the bonding was due to direct Al-Al bonding, while Sn was diffused sparsely among Al grain boundaries. The developed bonding technology is usable for wafer-level integration of LSI and MEMS in conjunction with hermetic sealing.
Consumer Preferences and Willingness to Pay for Country of Origin Labeled Product in Istanbul

Consumers' interest in locally produced foods is growing over the last years. Thus, studying consumers' preferences for local foods and understanding the underlying causes of this demand increase and willingness to buy local food products could be conducive to further development of local food markets. Country-of-origin labeling (COOL) is being implemented in different forms and degrees in Turkey and other countries across the world. In this study we focused on two different COOL food products from Turkey, namely Ayvalik olive oil and Ezine cheese. A survey was undertaken in the area of Istanbul aimed at studying consumer preferences for those products compared to their conventional counterparts. The willingness to pay equation has been specified as a two-step decision process, taking into account the results obtained from the two consecutive questions, willingness to pay a premium and how much consumers are willing to pay. If the decision will be consuming COOL product, different demand models (Heckmann models) were estimated. For these products, for that purpose, different price sets were defined to the consumers to evaluate how much they will pay extra. In conclusion we found out that, consumers are aware of those products and willing to pay a price premium. For AyvalA±k Olive oil they are willing to pay 82 percentages more than conventional alternatives. For Ezine Cheese they are willing to pay a premium almost 4 times up to conventional cheese products.
Traumatic brain injury induces long-lasting changes in immune and regenerative signaling

There are no existing treatments for the long-term degenerative effects of traumatic brain injury (TBI). This is due, in part, to our limited understanding of chronic TBI and uncertainty about which proposed mechanisms for long-term neurodegeneration are amenable to treatment with existing or novel drugs. Here, we used microarray and pathway analyses to interrogate TBI-induced gene expression in the rat hippocampus and cortex at several acute, subchronic and chronic intervals (24 hours, 2 weeks, 1, 2, 3, 6 and 12 months) after parasagittal fluid percussion injury. We used Ingenuity pathway analysis (IPA) and Gene Ontology enrichment analysis to identify significantly expressed genes and prominent cell signaling pathways that are dysregulated weeks to months after TBI and potentially amenable to therapeutic modulation. We noted long-term, coordinated changes in expression of genes belonging to canonical pathways associated with the innate immune response (i.e., NF-κB signaling, NFAT signaling, Complement System, Acute Phase Response, Toll-like receptor signaling, and Neuroinflammatory signaling). Bioinformatic analysis suggested that dysregulation of these immune mediators—many are key hub genes—would compromise multiple cell signaling pathways essential for homeostatic brain function, particularly those involved in cell survival and neuroplasticity. Importantly, the temporal profile of beneficial and maladaptive immunoregulatory genes in the weeks to months after the initial TBI suggests wider therapeutic windows than previously indicated.
EasyChair Preprint No 877 Fully Convolution Networks for Buildings Segmentation in High Spatial Resolution Remote Sensing Images

Segmentation with high precision of buildings in high resolution remote sensing images is an important issue for the construction of digital city and classification the military targets. The main technology of this paper is based on FCN-VGG (Fully Convolution Networks-Visual Geometry Group) to implement the building segmentation in remote sensing image, in which the features are extracted by multiple convolution and the transposed convolution is employed to recover the original image size. The valid experiment results show that the method proposed could overcome disturbance produced by roads, trees, pedestrians, the cross-bedding of buildings effectively. Meanwhile, the multiexperiment demonstrates the generalization of the buildings segmentation in multi-resolutions. Keywords—fully convolution network, buildings segmentation, remote sensing image
dentification and genetic characterization of an ethylene-dependent olygalacturonase from apricot fruit

During fruit ripening a loss of firmness occurs, which is a key factor limiting postharvest life. In apricot, Prunus armeniaca L. , a wide range of fruit firmness at commercial maturity has been observed in different cultivars. Endopolygalacturonase (endoPG) activity has been reported to be associated with differences in firmness in many fruit species, but never in apricot. In this paper, we reported the identification of an apricot cDNA (PaPG) coding for an endoPG-like protein with 393 amino acids. Protein sequence comparison with known polygalacturonases (PGs) revealed that multiple features as conserved domains and functional residues and a predicted signal peptide were present in PaPG. Moreover, a phylogenetic analysis of this and other plant PGs placed PaPG into a clade containing endoPGs expressed in fruit, abscission and dehiscence zones without a propeptide sequence, very close to PRF5 from peach (Prunus persica L. Batsch). PaPG gene expression increased during postharvest storage of the fruit, correlating with fruit softening and ethylene release, and it responded to exogenous ethylene treatments. We localized the PaPG gene in apricot linkage group 4 after genetic mapping based on SNP analysis, in a position apparently syntenic to the PRF5 locus from peach. Results obtained offer genetic evidence supporting the hypothesis that PaPG and PRF5 are orthologous genes, and consequently position PaPG as a gene of interest for studies on fruit softening in apricot, and contribute to the development of molecular tools h long for breeding apricots wit
AN ECONOMIC ANALYSIS OK FOREST EXTRACTION AND ITS LINKAGE TO COMMUNITY LIVELIHOODS : As ' 1 fHE CASE OF KAKAMEGA RAINFOREST . ^ ^

IX 1.0 INTRODUCTION. 1 1.1 Background. 1 1.1.1 A historical overview o f the management o f Kakamega forest . 3 1.2 Problem Statement. 6 1.3 Objectives of the Study. 9 1.3.1 General objective. 9 1.3.2 Specific objectives.9 1.4 Justification for this Study . 9 1.5 Hypotheses to be tested.10 1.6 SCOPE AND LIMITATIONS AF STUDY.11 2.0 LITERATURE REVIEW.13 2.1. Forest conservation and utilization.14 2.2. Socioeconomic factors influencing forest extraction. 16 3.0 METHODOLOGY. 18 3.1. Theoretical framework.18 3.2. Conceptual Frame work.19 3.3. Empirical Models for Forest Extraction. 20 3.4. Description of the Study Area. 26 3.5. Data Needs, Sources and Method of collection.28 3.6. The Survey Design. 29 3.7. Data Analysis.30 4.0 RESULTS AND DISCUSSIONS.43 V I 4.1 Descriptive Statistics 43 4.1.1 Household Characteristics.43 4.1.2 Farm size.44 4.1.3. Household income and labour use.44 4.1.4. Forest extraction.45 4.2 Analysis of Benefits from Extraction.47 4.3 Effect of different factors on participation in forest product extraction. 50 4.4 EFFECT OF ANALYZED FACTORS ON THE LEVEL OF FOREST EXTRACTION.52 5.0 CONCLUSION AND RECOMMENDATIONS. 59 5.1. Conclusion.59 5.2 Recommendations.60 REFERENCES. 63 APPENDICES.68 Appendix (i): Gross Margin for One Acre Tea (4356 bushes) 2004/2005.68 Appendix (ii) Weights used for construction of "household wealth" variable. 69 Appendix (hi): Questionnaire. 70
TREATMENT OF RHEUMATOID ARTHRITIS IN BASRAH : CLINICAL EFFICACY AND TOXICITY OF SULFASALAZINE USED ALONE OR IN COMBINATION WITH DICLOFENAC SODIUM

Background: Racial variation in the clinical presentation of rheumatoid arthritis (RA) and its response to treatment is well known. Ethnicity and associated socioeconomic factors make it necessary to study the effectiveness of the antirheumatic drugs such as sulfasalazine (SSZ) in our RA patients, and to what extent it interacts with the nonsteroidal anti-inflammatory drug (NSAID); diclofenac. Objective: To investigate the efficacy and toxicity of sulfasalazine alone or in combination with diclofenac in the treatment of moderate to severe RA. Methods: A three month-randomized clinical trial was conducted on patients with moderate to severe RA: Group I: received SSZ (500 mg orally twice daily), and Group II: received SSZ plus diclofenac sodium 100mg SR tablets once daily. Evaluation involved: pain, morning stiffness, joint function, patients and physician global assessment, radiological assessment, ACR criteria, laboratory findings and drug adverse effects. Results: Only 17 patients out of 20, managed to complete the 12 week treatment course. Oral SSZ (500mg twice daily for 3 months) resulted in a statistically significant clinical improvement after 12 weeks of treatment. The average percent improvement in six clinical parameters was 21.1%. The 20% improvement using ACR criteria involved 11% of patients. The improvement occurred especially in the number of swollen joints and in joint pain. The overall improvement that occurred two weeks after treatment with SSZ continued at the same level over the 12 week treatment period. No statistically significant changes were detected in the laboratory parameters measured including ESR. No radiological progression was found 12 weeks after treatment in joint space narrowing and joint erosion. SSZ reduced symptoms reported by patients before treatment by 57.4%. Diclofenac as a sustained release formulation administered concomitantly with SSZ did not change the improvement caused by SSZ as measured by the six clinical parameters (23% versus 23.4%). However, the ACR20 increased from 11% to 25%. No effect on laboratory measurements was found. Diclofenac in combination with SSZ reduced the symptoms reported by patients by 70.6% compared with 57.4% by SSZ alone. Conclusion: SSZ treatment for 12 weeks caused mild to moderate improvement in all measured clinical parameters, especially in the number of swollen joints and in joint pain. Diclofenac as a sustained release formulation, given with SSZ, did not change the improvement caused by SSZ as measured by six clinical parameters, although it increased the ACR20 of SSZ from 11% to 25%.
Relationship in broiler breast meat quality and some blood parameters: implications of different colours clothes and visual human contact.

The goals of this research were to estimate the phenotypic relationship among various breat meat quality traits, blood parameters and tonic immobility from a broiler and to describe the relation among these variables. Broiler chicks were devided into different groups: (1) colour clothing groups represented four different colours as red, blue, green, and gray and (2) the chicks that were subjected to visual human contact for 60 and 300 sec. A total of 192 chicks, one day-old, were randomly assigned to eight treatment groups according to the colour clothing and visual human contact. Hatching weights for red, blue, green and gray clothing colour groups were found as 47.10, 48.35, 46.67, and 47.05 g, and for 60 and 300 sec visual human contact groups were determined as 47.34 and 47.24 g, respectively. Cooking loss had a significant negative relationship with pH at 15 minutes after slaughter (pH15) in the red clothes group. Water holding capacity had a negative correlations (r=-0.355 and -0.489) with pH at 24 hours after slaughter (pHu) in the 60 and 300 sec groups, respectively. Total protein level had a high degree and positive correlation (r=0.675) with cholesterol level in the red clothes group. Tonic immobility (TI) duration had significant relationship with TI induction in the green clothes group. The a* colour value of breast meat showed a moderate negative and significant correlation with the variables L* value of breast meat (-0.574 (P<0.01) and -0.373 (P<0.05), respectively) in gray clothing and 300 sec visual contact group. These finding have a lot of implications on the use of gray colour clothing and 300 s visual contact to improve meat quality for welfare in broilers.
FINGERPRINT DAMAGE SIMULATION

The goal of this thesis is to design and implement an application for the synthetic fingerprint damage simulation. When I studied the literature, my focus was laid mainly on the project SFinGe which is a pioneer in this area. I specified the area of interest to optical or capacitive touch sensors and the fingerprint damage caused by the pressure and the moisture, the damage and the dirt on the sensor and the skin deformation. I designed a way how to implement these factors which damage the synthetic fingerprint so that the fingerprint looks like a real one. These methods use morphological operators and a model of plastic distortion in fingerprint images. The most successful methods result in 62.5% worse score in a commercial product compared to the original image and in one class worse result according to the standard of fingerprint image quality. The main benefit of this work is damaging synthetic fingerprints so that they are proven to be worse than the original and the design of an application that allows an expansion by other methods.
85-87 Andonian. Engl

Population genetic structure of Armenians living in Iran and in Diasporal community of London was comparatively studied based on 12 UEP and 6 STR Y chromosome markers. The results of the study have shown that genetically the two groups significantly differ from each other. This i ndicates that the dataset of Iranian Armenians collected outside Iran, due to historical and geographic peculiarities of population dispersal, is substantially biased and d oes not adequately represent the original community established in Iran since the be ginning of 17 century AD.
From Flasks to Applications : Combinatorial Chemistry and High-Throughput Synthesis of High-Performance Complex Nanomaterials using Automated Synthesis

Highly emissive nanoparticles are extremely attractive options for a variety of applications, including, but not limited to, solid state lighting [1,2], optoelectronics [3], and sensing [4]. However, to utilize these and other nanoparticle materials on a commercially viable scale to meet demand, the design, synthesis, optimization, and scale up of the material must be extremely efficient and consistent across batches. It has been suggested that from development of design to optimized production, more than 100 reactions may need to be completed before the material can be used, which requires time and manpower [5]. We present our Fully Automated Batch Reactor System (FABRS) which drastically cuts down on the time required for both materials discovery and optimization.
INVESTIGATING SHOPPING TOURISM ALONG THE BORDERS OF HUNGARY – A THEORETICAL PERSPECTIVE

The complex and interrelated relationship between shopping and travelling is an interesting and current field of study. Mass consumption and tourism have become some of the most important factors of economic growth in many countries of the world. This article attempts to outline the theoretical backgrounds of shopping tourism by introducing the views and results of the most relevant researchers in this field. First, the international literature is reviewed, then the most comprehensive studies in Hungary are introduced, finally the results of cross-border case studies are outlined with a special emphasis on the northeastern borders of Hungary.
INTERNALIZATION OF BRAYA ' S AMAZING VALUES AS A MANAGEMENT OF BUSINESS CONTROL IN ENDEK CLOTHING SME AND KLUNGKUNG SONGKET ( CASE STUDY APPROACH ) Ni Ketut

The research study in this article is in the form of values of Brama as a social capital in the development of creative industries by the craftsmen who are members of Small and Medium Enterprises (SMEs) crafts of endek ikat and songket Klungkung. Values align Braya to SME leadership patterns, human relationships with other SMEs, workers, and customers, and social responsibility in order to provide welfare to their workers. Research method, This research use model (Research and Development). The sample of 15 SMEs involved in the develompment stage was chosen purposively. Needs analysis was conducted as a basis for designing an evaluation model of the planting of values of Braya based on local genius. Outcomes: Braya's Branding Values Internalized by SMEs, their relevance influences SMEs' social responsibility attitude, combines empowerment and entrepreneurship aspects based on kinship and togetherness.
Effect of Vernonia amygdalina ( Bitter Leaf ) Extract on Growth Performance , Carcass Quality and Economics of Production of Broiler Chickens

Vernonia amygdalina (bitter leaf) is a shrub or small tree that grows throughout tropical Africa. It is a very important protective food and useful for the maintenance of health and treatment of various diseases. The purpose of this study is to determine the effect of Vernonia amygdalina (VA) extract on growth performance, carcass quality and economics of production of broiler chicks. Sixty 7day old Oba-Marshall broiler chicks were used for 54 days water infusion feeding trial. Four water infusion levels 0ml, 25ml, 50ml and 75ml of VA per litre of (clean) drinking water designated as T1, T2, T3 and T4 were used. Birds were randomly assigned in a completely randomized design (CRD) experiment with each treatment replicated three times (5 birds per replicate), daily feed and water were offered ad libitum. Data were collected on feed intake, weekly body weight and economics of production. The result showed that there was no significant (p>0.05) difference in weekly feed intake of birds among the four treatments, T1, T2, T3 and T4. Significant (p<0.05) differences were observed in the final body weight, weekly weight gain and feed conversion ratio of birds among the treatments. The result for carcass quality showed significant differences (p<0.05) in slaughtered weight, carcass weight, carcass dressing International Journal of Agriculture and Earth Science Vol. 2 No.1 ISSN 2489-0081 2016 www.iiardpub. org IIARD – International Institute of Academic Research and Development Page 59 percentage, drum stick, thigh, breast, giblets and back but no significant (p>0.05) difference was observed in wing, abdominal fat, head, intestine length and intestine weight. There was decreased mortality of broilers fed 50ml and 75ml of VA. Birds on T3 (50%) had the best feed conversion ratio (2.49%) and least cost benefit ratio. It can be concluded that the birds fed 50% (T3) and 75% (T4) infusion level gave better result, highest revenue and can be recommended to achieve better feed conversion ratio, weight gain and carcass quality.
1 A Conditional Regime Switching CAPM

The standard Capital Asset Pricing Model (CAPM) is simple, intuitive, and grounded in sound economic theory. Yet, almost half a century’s worth of empirical testing has so far failed to demonstrate its relevance. One major reason given for the CAPM’s empirical failure is that beta is not the sole measure of systematic risk. In other words, the standard CAPM does not hold. Another important explanation is that the CAPM may hold conditionally rather than unconditionally. The standard CAPM fails to explain the crosssection of returns because it ignores the fact that both the risk and the price of risk are timevarying. The search for conditional models has led researchers to either disregard the theory behind the CAPM or to use statistical procedures that are too complex to be replicated by other researchers and practitioners. In this paper we propose a conditional model that is compatible with the standard CAPM while remaining simple and accessible to both researchers and practitioners. Beta and the risk premium are assumed to be timevarying, with the latter being associated with bull and bear states. We find strong support for the conditional CAPM with beta explaining both bull and bear markets. While the bear market ex-post risk premium is negative, the weighted average risk premium is positive and highly significant.
Development of a Brazilian anticholinergic activity drug scale

ABSTRACT Objective To develop a scale of anticholinergic activity drugs used in Brazil, to be applied in health care and pharmacoepidemiology research. Methods We performed a literature review on PubMed/MEDLINE® to identify previously published scales of anticholinergic drugs. This scale started with anticholinergic drugs, and those with known anticholinergic activity as per the 4th level, chemical-therapeutic subgroup, of the Anatomical Therapeutic Chemical classification. We also included drugs with high anticholinergic activity, as described in a list of potentially inappropriate medications for use in older adults, according to the 2015 American Geriatrics Society Beers Criteria. Drugs listed in at least two anticholinergic scales were added. Then we verified which drugs in the previous steps were marketed in Brazil. We assigned a score of 1, 2 and 3, based on their anticholinergic action. Results A total of 273 anticholinergic drugs were identified, of which 125 were included in the scale. We identified 45 (36.0%) drugs with a score of 3, 13 (10.4%) with a score of 2, and 67 (53.6%) with a score of 1. Drugs for the nervous and respiratory systems were the most frequent in the scale. Eight drugs were not present in previous scales. Conclusion The methodology used for development of the Brazilian anticholinergic activity scale is simple, systematized, reproducible and easy to update. The scale allows evaluating the impact of anticholinergic burden on health outcomes, and can potentially contribute to pharmacoepidemiology research, leading to more accurate measurements of anticholinergic activity.