Miracle-dz/UniFAR-FTUs huggingface dataset:
Goal attainment scaling—community-based: A method to incorporate personalized outcomes into intervention research with youth and adults on the autism spectrum

Given the wide heterogeneity in the autism population, one challenge for intervention studies is to identify outcome measures that have similar meaning across individuals. This is particularly pronounced in intervention studies of adults with autism spectrum disorder, where outcomes such as employment, independence, or community living are common targets. However, these outcomes can be more challenging to obtain for those who have greater support needs, for example, and therefore may be more or less salient depending on the sample under study. Goal attainment scaling can help address this issue as it allows individuals to identify personally meaningful goals and track progress toward these goals. While goal attainment scaling is gaining popularity in the autism field as an outcome measure, most intervention studies that use goal attainment scaling have been situated in clinical or school settings. Generating reliable and scalable goals outside of these settings can be challenging. In this article, we describe the promise of goal attainment scaling for tailoring individualized outcomes among youth and adults with autism spectrum disorder and discuss the challenges of current goal attainment scaling methods in community-based intervention research. We then describe a new goal attainment scaling approach that is rigorous, practical, and can be used across research settings to measure individualized outcomes. Lay abstract Among people with autism—all who have the same diagnosis—there are major differences on a nearly limitless number of areas, such as language, daily living skills, intellectual ability, sensory difficulties, and physical and mental health diagnoses. Despite these many differences, the targeted outcomes of intervention studies are often measured the same way across autistic adults, including outcomes such as getting a job, achieving greater independence, or getting more services. People have different goals and abilities, and it is important to have a way for intervention studies to measure outcomes in a way that is more personal to each individual. To address this issue, we developed a new approach—called “Goal Attainment Scaling—Community-based” or GAS-CB—to measure individualized outcomes across different research settings. In this article, we describe the need for individualized outcomes in autism intervention research and current approaches to gathering these outcomes, with our discussion focused on a method called goal attainment scaling. We then describe reasons why current goal attainment scaling approaches might not be useful in intervention research that takes place in the community. Finally, we discuss a new goal attainment scaling approach (GAS-CB) that can be flexibly used for research participants with very different characteristics.
Diversity Image Coding Using Irregular Interpolation

Diversity “multiple description” (MD) source coding promises graceful degradation in the presence of a priori unknown number of erased packets in the channel. A simple coding scheme for the case of two packets consists of oversampling the source by a factor of two and delta-sigma quantization. This approach was applied successfully to JPEG-based image coding over a lossy packet network, where the interpolation and splitting into two descriptions are done in the discrete cosine transform (DCT) domain. Moreover, unlike the classical source-channel separation approach - which is designed for a predetermined number of erasures (say, <inline-formula> <tex-math notation="LaTeX">$K$ </tex-math></inline-formula> out of <inline-formula> <tex-math notation="LaTeX">$N$ </tex-math></inline-formula>), hence its distortion does not improve when the channel behaves better than expected - an MD coding scheme aims to achieve a better reconstruction quality when more or all the <inline-formula> <tex-math notation="LaTeX">$N$ </tex-math></inline-formula> descriptions are received at the decoder side. The extension to a larger number of descriptions, however, suffers from noise amplification whenever the received descriptions form a non-uniform sampling pattern. In this work, we examine inter- and intra-block interpolation methods, and show how noise amplification can be reduced by redesigning the interpolation filter at the encoder. Specifically, for a given total coding rate, we demonstrate that an “irregular” interpolation filter is robust to the pattern of received packets over all (<inline-formula> <tex-math notation="LaTeX">$K$ </tex-math></inline-formula> out of <inline-formula> <tex-math notation="LaTeX">$N$ </tex-math></inline-formula>) patterns, with some degradation relative to low-pass (LP) interpolation in the case where all <inline-formula> <tex-math notation="LaTeX">$N$ </tex-math></inline-formula> packets arrived. We provide experimental results comparing LP and irregular interpolation filters, and examine the effect of noise shaping on the trade-off between the central distortion (receiving all packets) and side distortion (receiving <inline-formula> <tex-math notation="LaTeX">$K$ </tex-math></inline-formula> packets).
Invariance of the Household Food Insecurity Access Scale Across Different Groups of Adolescents and Young Adults

Background: Cross-group comparisons of household food insecurity and its associations using multiple-item scales assume that scale scores can be interpreted as identical across groups. However, scores should not be interpreted as identical across groups without evidence of measurement invariance. Noninvariant measures indicate that the underlying construct may be different across groups. Objective: To determine whether the Household Food Insecurity Access Scale (HFIAS) is invariant across different groups of Ghanaian and South African youth aged 15 to 24. Methods: We analyzed cross-sectional quantitative data from 1437 and 4165 young South Africans and Ghanaians, respectively. Multi-group confirmatory factor analysis was used to examine whether the HFIAS was invariant across different groups of youth, including sex (male or female), age group (middle adolescence, late adolescence, or emerging adulthood), and receipt of child support grant (yes or no). We assessed 3 levels of invariance: configural, metric, and scalar. The model fit between nested models was compared using χ2 difference testing. Results: Invariance tests indicated that the HFIAS had configural, metric, and scalar invariance across different groups of Ghanaian and South African youth. Model fit statistics across all invariance levels indicated good fit of our hypothesized model with the observed data. χ2 difference testing results were not statistically significant across all nested models. Conclusions: Food insecurity, as measured by the HFIAS, meant the same thing for different groups of Ghanaian and South African youth. Evidence of invariance means that the HFIAS scores could be interpreted as identical across youth groups in our study.
Fast calculation method of transient temperature rise of motor for electro-mechanical braking

Electro-mechanical braking is a new braking mode of rail vehicles, which has the advantages of compact structure, fast response speed, and high precision. It is a new braking technology that conforms to the development trend of full electrification and full intelligence of rail transit brake devices. Due to the special power demand of the electro-mechanical braking device, the electro-mechanical braking motor has a short-time and intermittent working mechanism and is in the state of blocking during working, resulting in its high-temperature rise. Therefore, it is necessary to calculate the temperature rise of the motor quickly and accurately at the beginning of its design. To address this problem, based on the coupling calculation of the equivalent thermal circuit method and the equivalent magnetic circuit method, a fast temperature rise calculation method of the motor is proposed. Then, using the fast calculation method, the temperature rise of the electro-mechanical brake motor under different working periods and wind speed is calculated. By function fitting the calculated results, the motor temperature rise curve fitting function is obtained, which can accurately predict the temperature rise of the motor under different working conditions. It provides a theoretical basis for the use of electro-mechanical braking motor in different working conditions and also provides a reference for the design of the electro-mechanical braking motor.
“Rescue” of Nonparticipants in Colorectal Cancer Screening: A Randomized Controlled Trial of Three Noninvasive Test Options

This trial of screening for those at average risk for colorectal cancer targeted past fecal-test nonparticipants and compared participation rates for mailed invitations offering a fecal test, blood test, or choice of either. Although there was no clear advantage between strategies, factors associated with participation differed between each strategy. Few studies have directly targeted nonparticipants in colorectal cancer screening to identify effective engagement strategies. We undertook a randomized controlled trial that targeted nonparticipants in a previous trial of average-risk subjects which compared participation rates for mailed invitations offering a fecal test, a blood test or a choice of either. Nonparticipants (n = 899) were randomized to be offered a kit containing a fecal immunochemical test (FIT), directions on how to arrange a blood DNA test, or the option of doing either. Screening participation was assessed 12 weeks after the offer. To assess the cognitive and attitudinal variables related to participation and invitee choice, invitees were surveyed after 12 weeks, and associations were investigated using multinomial logistic regression. Participation rates were similar between groups (P = 0.88): 12.0% for FIT (35/292), 13.3% for the blood test (39/293), and 13.4% for choice (39/290). Within the choice group, participation was significantly higher with FIT (9.7%, 28/290) compared with the blood test (3.8%, 11/290, P = 0.005). The only variable significantly associated with participation was socioeconomic status when offered FIT, and age when offered choice but there was none when offered the blood test. Survey respondents indicated that convenience, time-saving, comfort, and familiarity were major influences on participation. There was no clear advantage between a fecal test, blood test, or choice of test although, when given a choice, the fecal test was preferred. Differences in variables associated with participation according to invitation strategy warrant consideration when deciding upon an invitation strategy for screening nonparticipants. Prevention Relevance: This trial of screening for those at average risk for colorectal cancer targeted past fecal-test nonparticipants and compared participation rates for mailed invitations offering a fecal test, blood test, or choice of either. Although there was no clear advantage between strategies, factors associated with participation differed between each strategy.
Chronic Pelvic Pain in Women

Chronic pelvic pain resulting from varicose veins of the small pelvis is a multidisciplinary problem. A key cause of pelvic congestion is congenital or acquired gonadal valve failure. Ultrasound and Doppler examination for chronic pelvic pain allows in most cases to diagnose pelvic varicose veins. Multispiral computed tomography or magnetic resonance imaging details the nature and extent of the pathology. Selective phlebography is considered the gold standard for diagnosing varicose veins of the small pelvis. Conservative treatment with phlebotropic drugs is prescribed for limited pelvic varicose veins. Surgical treatments include open resection and retroperitoneal and transperitoneal laparoscopic gonadal vein excision or clipping. The most effective is minimally invasive endovascular occlusion of reflux veins using spiral technologies and sclerosants. The left ovarian vein is reduced more often. The decision on bilateral embolization of blood vessels depends on the severity of changes in veins and the intensity of blood reflux. A decrease in the intensity or disappearance of pain in the pelvic area is achieved in 80-100% of cases after the procedure. Diagnosis of this condition is difficult due to the fact that the appearance of pelvic varicose veins is nonspecific and includes symptoms of surgical, urological,
Treatment and rehabilitation of stroke patients in India: A gendered analysis based on repeated cross-sectional national sample surveys on health, 2014 and 2019

Abstract We attempt a gendered inspection of sex differentials in care following stroke in India using data from two rounds of NSSO. While almost all men and women receive allopathic care, a higher percentage of women (51.8%) were treated in public hospitals compared to men (32.6%) in 2014 and 2017–18 (45.8% vs 41.4%). Men were preponderantly treated in private hospitals (67.4%) compared to women (48.2%) in 2014 and 2017–18 (58.6% vs 54.2%). We provide evidence that for rehabilitation, at the highest decile for expenditure, men spend more than women. This preliminary exploration is indicative of a gendered dimension in care-seeking for stroke.
Evaluating the Feasibility and Acceptability of the Lifestyle Enhancement for ADHD Program.

OBJECTIVE To evaluate the feasibility and acceptability of the Lifestyle Enhancement for Attention Deficit Hyperactivity Disorder (ADHD) Program (LEAP), a novel parent behavior management training program that promotes physical activity (PA) and positive health behaviors and is enhanced with mobile health technology (Garmin) and a social media (Facebook) curriculum for parents of children with ADHD. METHODS The study included parents of children ages 5-10 years diagnosed with ADHD who did not engage in the recommended >60 min/day of moderate to vigorous PA based on parent report at baseline. Parents participated in the 8-week LEAP group and joined a private Facebook group. Children and one parent wore wrist-worn Garmin activity trackers daily. Parents completed the Treatment Adherence Inventory, Client Satisfaction Questionnaire, and participated in a structured focus group about their experiences with various aspects of the program. RESULTS Of 31 children enrolled, 51.5% had ADHD combined presentation, 36.3% with ADHD, predominately inattentive presentation, and 12.1% had unspecified ADHD (age 5-10; M = 7.6; 48.4% female). Parents attended an average of 86% of group sessions. On average, parents wore their Garmins for 5.1 days/week (average step count 7,092 steps/day) and children for 6.0 days/week (average step count 9,823 steps/day). Overall, parents and children were adherent to intervention components and acceptability of the program was high. CONCLUSIONS Findings indicate that the LEAP program is an acceptable and feasible intervention model for promoting PA among parents and their children with ADHD. Implications for improving ADHD symptoms and enhancing evidence-based parent training programs are discussed.
Exploring experiences of COVID‐19‐positive individuals from social media posts

Abstract Aims This study aimed to explore the experience of individuals who claimed to be COVID‐19 positive via their Twitter feeds. Background Public social media data are valuable to understanding people's experiences of public health phenomena. To improve care to those with COVID‐19, this study explored themes from Twitter feeds, generated by individuals who self‐identified as COVID‐19 positive. Design This study utilized a descriptive design for text analysis for social media data. Methods This study analysed social media text retrieved by tweets of individuals in the United States who self‐reported being COVID‐19 positive and posted on Twitter in English between April 2, 2020, and April 24, 2020. In extracting embedded topics from tweets, we applied topic modelling approach based on latent Dirichlet allocation and visualized the results via LDAvis, a related web‐based interactive visualization tool. Results Three themes were mined from 721 eligible tweets: (i) recognizing the seriousness of the condition in COVID‐19 pandemic; (ii) having symptoms of being COVID‐19 positive; and (iii) sharing the journey of being COVID‐19 positive. Conclusion Leveraging the knowledge and context of study themes, we present experiences that may better reflect patient needs while experiencing COVID‐19. The findings offer more descriptive support for public health nursing and other translational public health efforts during a global pandemic.
Fabrication and Evaluation of Celecoxib Oral Oleogel to Reduce the Inflammation of Ulcerative Colitis

Oleogel consists of hydrophobic solvent and an oleogelator. In this study, attempts were made to study the influence of Celecoxib solubility, concentration and dispersability on its release, absorption, and biological performance. Oleogels were prepared to study the formulation variables on its stability and release. Castor oil was selected as the oil and the oleogelator concentration was 4.5% w/w. F3 revealed the highest release and stability compared to other formulae. The percent permeated across the rat intestine showed a 7.5-fold increase over free Celecoxib, and its lifetime was found to be greater than 18 months. The efficacy of free Celecoxib and oleogel formulae to treat rats with ulcerative colitis was done via the induction of ulcerative colitis (UC) through administration of 5% dextran sodium sulphate (DSS). Celecoxib besides its formulae significantly reduced the release of Leucine rich 2 glycoprotein (LRG), Myeloperoxidase (MPO), Tumor necrosis factor–α (TNF-α), proinflammatory cytokine expression, High mobility group box 1 (HMGB1), Nuclear factor kappa B (NF-ΚB), Trefoil Factor 3 (TFF3), Metalloproteinase-3 (MMP3), and miRNA31. Moreover, F3 significantly increased the colonic cAMP in DSS treated rats and reduced the intestinal inflammation beside healing of mucosa and restitution of the epithelium of the gastrointestinal tract.
Fabrication and characterization of bifunctional spherical polyelectrolyte brushes

Abstract In this work, we prepared two kinds of dual-responsive spherical polyelectrolyte brushes (SPBs) with narrow distribution, of which cores were composed of polystyrene and grafting from copolymers of poly(N-isopropyl acrylamide-co-acrylic acid) (P(NIPAM-AA)) and poly(acrylic acid-co-N,N-diethyl acrylamide) (P(AA-DEA)), respectively. Both kinds of SPBs could response to pH and temperature stimulations by swelling/deswelling shell and electrophoretic mobility (EPM) changes. The low critical solution temperature of SPBs can be fine-tuned in the range of 28–45 ℃ at pH 3–9. Due to the different reactivity of comonomers (NIPAM and AA or DEA and AA), the acrylic acid (AA) unties were distributed at the inner shell of P(AA-DEA) and outer shell of P(NIPAM-AA), respectively, which led to different responses toward pH, temperature, and ionic strength, such as the abnormal ‘salt effect’ of P(AA-DEA) at low ionic strength and lower shell shrinkage ratio (SR) of P(NIPAM-AA). The dye adsorption in SPBs further confirmed the distribution of AA units.
Stressful life events and serum triglyceride levels: the Cardiovascular and Metabolic Diseases Etiology Research Center cohort in Korea

OBJECTIVES Elevated serum triglyceride levels are a risk factor for developing cardiovascular disease. A number of studies have demonstrated a positive association between psychological stress and serum triglyceride levels. However, there is limited evidence regarding the impact of stressful life events (SLEs) on serum triglyceride levels in the healthy population. Therefore, we evaluated the independent association between SLEs and serum triglyceride levels in a middle-aged Korean population. METHODS We analyzed a sample of 2,963 people (aged 30-64 years; 36% men) using baseline data from the Cardiovascular and Metabolic Diseases Etiology Research Center (CMERC) cohort study. The Korean version of the Life Experience Survey questionnaire was used to measure the presence and positive/negative impact of SLEs. Hypertriglyceridemia was defined as a fasting serum triglyceride level of ≥ 150 mg/dL. RESULTS Of the 2,963 participants, 33.1% reported at least 1 SLE over the past 6 months and 24.8% had hypertriglyceridemia. Even after adjusting for potential confounders, the serum triglyceride level was significantly associated with the total number of SLEs in men (3.333 mg/dL per event; p= 0.001), but not in women (0.451 mg/dL per event, p= 0.338). Hypertriglyceridemia was also associated with having 4 or more SLEs with positive effects (odds ratio [OR], 2.57; 95% CI, 1.02 to 6.46) and 4 or more SLEs with negative effects (OR, 1.99; 95% CI, 1.16 to 3.41) in men. CONCLUSIONS Our findings suggest that SLEs may increase the risk of hypertriglyceridemia in middle-aged men.
Current Advancements in Animal Models of Postsurgical Lymphedema: A Systematic Review.

SIGNIFICANCE Secondary lymphedema is a debilitating disease caused by lymphatic dysfunction characterized by chronic swelling, dysregulated inflammation, disfigurement, and compromised wound healing. Since there is no effective cure, animal model systems that support basic science research into the mechanisms of secondary lymphedema are critical to advancing the field. Recent Advances: Over the last decade, lymphatic research has led to the improvement of existing animal lymphedema models and the establishment of new models. Although an ideal model does not exist, it is important to consider the strengths and limitations of currently available options. In a systematic review adhering to the PRISMA guidelines, we present recent developments in the field of animal lymphedema models and provide a concise comparison of ease, cost, reliability, and clinical translatability. CRITICAL ISSUES The incidence of secondary lymphedema is increasing, and there is no gold standard of treatment or cure for secondary lymphedema. FUTURE DIRECTIONS As we iterate and create animal models that more closely characterize human lymphedema, we can achieve a deeper understanding of the pathophysiology and potentially develop effective therapeutics for patients.
Effect of playing position, passage duration and starting status on the most demanding passages of match play in professional football

ABSTRACT The aims of this research were to analyse the effect that different playing positions, passage durations and starting status had on the most demanding passages (MDP) of play in professional football matches. Players were categorized by positions and the MDP of distance (DIS), high-speed running distance (HSRD) and sprinting distance (SPD) were analysed for four passage durations (1, 3, 5 and 10 minutes). The results indicated that DIS (p < 0.001), HSRD (p < 0.001) and SPD (p < 0.001) covered per minute decreased as the passage durations increased for all positions. Regarding the playing position, it had a significant effect on the DIS (p < 0.001), HSRD (p < 0.001) and SPD (p < 0.001) covered. In addition, although the results reported that the starting status had no significant effect on the DIS (p = 0.36) covered, it had a statistically significant effect on the HSRD (p = 0.01) and SPD (p < 0.001) covered. Coaching and medical departments should consider the impact that these variables have on players’ performance when designing training drills aimed at preparing the player for the competitive demands.