Miracle-dz/UniFAR-FTUs huggingface dataset:
Direct repression of evening genes by CIRCADIAN CLOCK-ASSOCIATED 1 in Arabidopsis circadian clock

Direct repression of evening genes by CIRCADIAN CLOCK-ASSOCIATED 1 in 1 the Arabidopsis circadian clock 2 3 Mari Kamioka, Saori Takao, Takamasa Suzuki, Kyomi Taki, Tetsuya 4 Higashiyama, Toshinori Kinoshita, Norihito Nakamichi 5 Affiliations: a School of Agriculture, Nagoya University, Furo-cho, Chikusa, 6 Nagoya 464-8601, Japan, Institute of Transformative Bio-molecules, Nagoya 7 University, Furo-cho, Chikusa, Nagoya 464-8601, Japan, Exploratory Research 8 for Advanced Technology (ERATO) Higashiyama Live-Holonics Project, Nagoya 9 University, Furo-cho, Chikusa, Nagoya 464-8602, Japan, College of Bioscience 10 and Biotechnology, Chub University, 1200 Matsumoto-cho, Kasugai 487-8501, 11 Japan, e Division of Biological Science, Graduate School of Science, Nagoya 12 University, Furo-cho, Chikusa, Nagoya 464-8602, Japan. 13 14 Corresponding author e-mail: nnakamichi@itbm.nagoya-u.ac. jp 15 16 Short title: Direct regulation by CCA1 17 The author responsible for distribution of materials integral to the findings 18 presented in this article in accordance with the policy described in the 19 Instructions for Authors (www.plantcell.org) is: Norihito Nakamichi 20 (nnakamichi@itbm.nagoya-u.ac.jp). Contact information for the author 21 responsible for distribution of material should be provided. 22 Plant Cell Advance Publication. Published on March 3, 2016, doi:10.1105/tpc.15. 00737
Wood identification in objects of cultural heritage

We present the importance of exact wood identification for the purposes of conservation and restoration. We describe the procedures used such as sampling of wood, preparation of microscopic slides, and wood identification. The results of investigations of historic woods at the wood anatomy laboratory of the Department of Wood Science and Technology, Biotechnical Faculty are presented.
Ethnic/Racial Differences in 1-Year Persistence Rates by Institutional Status at Texas 4-Year Universities over Time

In this study, the 1-year persistence rates of four ethnic/racial groups (i.e., White, Black, Hispanic, and Asian) were analyzed as a function of institutional status (i.e., stayed or transferred) at Texas 4-year universities. Data were retrieved from the Texas Higher Education Coordinating Board Interactive Accountability system for the thirty-eight, 4-year Texas public universities for the 2014 academic year. For all ethnic/racial groups, statistically significant differences were present in the 1year persistence rates by institutional status. Effect sizes were very large. Regardless of race/ethnicity, students who transferred to another 4-year institution were statistically significantly less likely to persist than their peers who remained at the same 4-year institution. The 1-year persistence rates were 44%, 34%, 31%, and 27% higher for Hispanic, White, Asian, and Black students, respectively, who stayed at the same institution than for Hispanic, White, Asian, and Black students who transferred to a different institution. Based upon these results, implications for policy and for practice for 4-year universities are provided, along with suggestions for future research.
A Survey on Versions of TCP over WiMAX

— orldwide Interoperability for Microwave Access (WiMAX) is essentially a next-generation wireless technology that enhances broadband wireless access. (WiMAX) is a standards-based wireless technology for providing high-speed, last-mile broadband connectivity to homes and businesses and for mobile wireless networks. WiMAX is similar to Wi-Fi but offers larger bandwidth, stronger encryption, and improved performance over longer distances by connecting between receiving stations that are not in the line of sight. WiMAX uses Orthogonal Frequency Division Modulation (OFDM) technology, which has a lower power consumption rate. WiMAX can be used for a number of applications, including last-mile broadband connections, hotspots and cellular backhaul, and high-speed enterprise connectivity for business. It supports broadband services such as VoIP or video. WiMAX is also a possibility for backhaul technology in municipal Wi-Fi networks. WiMAX or 802.16 is definitely a hot topic and has a fair list of industry supporters. The paper focuses on the different congestion control mechanisms implemented by the Transmission Control Protocol (TCP). Reliable transport protocols such as TCP are tuned to perform well in traditional networks where packet losses occur mostly because of congestion. However, networks with wireless and other lossy links also suffer from significant losses due to bit errors and handoffs. TCP responds to all losses by invoking congestion control and avoidance algorithms, resulting in degraded end-to-end performance in wireless and lossy systems. In this Paper, we compare several schemes designed to improve the performance of TCP in such networks.
Dynamic Approximate Multiplicatively-Weighted Nearest Neighbors

We describe a dynamic data structure for approximate nearest neighbor (ANN) queries with respect to multiplicatively weighted distances with additive offsets. Queries take polylogarithmic time, while the cost of updates is amortized polylogarithmic. The data structure requires near-linear space and construction time. The approach works not only for the Euclidean norm, but for other norms in R d , for any fixed d . We employ our ANN data structure to construct a faster dynamic structure for approximate SINR queries, ensuring polylogarithmic query and polylogarithmic amortized update for the case of non-uniform power transmitters, thus closing a gap in previous state of the art. To obtain the latter result, we needed a data structure for dynamic approximate halfplane range counting in the plane. Since we could not find such a data structure in the literature, we also show how to dynamize one of the known static data structures.
Developmental Cell Small Ubiquitin-like modifier protein, SUMO enables plants to control growth independently of the phytohormone Gibberellic acid

: Plants survive adverse conditions by modulating their growth in response to changing environmental signals. Gibberellins (GA) play a key role in these adaptive responses by stimulating the degradation of growth repressing DELLA proteins. GA binding to its receptor GID1 enables association of GID1 with DELLAs. This leads to the ubiquitin-mediated proteasomal degradation of DELLAs and consequently growth promotion. We report that DELLA-dependent growth control can also be regulated independently of GA. We demonstrate that a proportion of DELLAs are conjugated to the Small Ubiquitin-like Modifier (SUMO) protein which increases during stress. We identify a SUMO interacting motif (SIM) in GID1 and demonstrate that SUMO-conjugated DELLA binds to this motif in a GA-independent manner. The consequent sequestration of GID1 by SUMO-conjugated DELLAs leads to an accumulation of non-SUMOylated DELLAs and subsequent beneficial growth restraint during stress. We conclude that plants have developed a non-GA mechanism to control growth during stress.
Union Types with Disjoint Switches

Union types are nowadays a common feature in many modern programming languages. This paper investigates a formulation of union types with an elimination construct that enables case analysis (or switches) on types. The interesting aspect of this construct is that each clause must operate on disjoint types. By using disjoint switches, it is possible to ensure exhaustiveness (i.e. all possible cases are handled), and that none of the cases overlap. In turn, this means that the order of the cases does not matter and that reordering the cases has no impact on the semantics, helping with program understanding and refactoring. While implemented in the Ceylon language, disjoint switches have not been formally studied in the research literature, although a related notion of disjointness has been studied in the context of disjoint intersection types . We study union types with disjoint switches formally and in a language independent way. We first present a simplified calculus, called the union calculus ( λ u ), which includes disjoint switches and prove several results, including type soundness and determinism . The notion of disjointness in λ u is in essence the dual notion of disjointness for intersection types. We then present a more feature-rich formulation of λ u , which includes intersection types, distributive subtyping and a simple form of nominal types. This extension reveals new challenges. Those challenges require us to depart from the dual notion of disjointness for intersection types, and use a more general formulation of disjointness instead. Among other applications, we show that disjoint switches provide an alternative to certain forms of overloading , and that they enable a simple approach to nullable (or optional) types . All the results about λ u and its extensions have been formalized in the Coq theorem prover.
A Proteomic Proﬁling Approach to Reveal a Novel Role of Brassica napus Drought 22 kD/Water-Soluble Chlorophyll-Binding Protein in Young Leaves during Nitrogen Remobilization Induced by Stressful Conditions 1

Despite its water-soluble chlorophyll-binding protein (WSCP) function, the putative trypsin inhibitor (TI) activity of the Brassica napus drought 22 kD (BnD22) protein and its physiological function in young leaves during leaf nitrogen (N) remobilization promoted by stressful conditions remains an enigma. Therefore, our objectives were to determine (1) if BnD22 is related to the 19-kD TI previously detected in B. napus young leaves, and (2) if the levels of BnD22 transcripts, BnD22 protein, and TI activity in young leaves are associated with plant responses to stress conditions (N starvation and methyl jasmonate [MeJA] treatments) that are able to modulate leaf senescence. Compared to control, N starvation delayed initiation of senescence and induced 19-kD TI activity in the young leaves. After 3 d with MeJA, the 19-kD TI activity was 7-fold higher than the control. Using two-dimensional electrophoresis gel, TI activity, and electrospray ionization liquid chromatography tandem mass spectrometry analysis, it was demonstrated that two 19-kD proteins with isoelectric points 5.0 and 5.1 harboring TI activity correspond to BnD22 perfectly. BnD22 gene expression, TI activities, and BnD22 protein presented similar patterns. Using polyclonal anti-WSCP antibodies of Brassica oleracea , six polypeptides separated by two-dimensional electrophoresis were detected in young leaves treated with MeJA. Electrospray ionization liquid chromatography tandem mass spectrometry analysis of six polypeptides conﬁrms their homologies with WSCP. Results suggest that BnD22 possesses dual functions (WSCP and TI) that lead to the protection of younger tissues from adverse conditions by maintaining metabolism (protein integrity and photosynthesis). By sustaining sink growth of stressed plants, BnD22 may contribute to a better utilization of recycling N from sources, a physiological trait that improves N-use efﬁciency.
A framework for designing supply chain disruptions management considering productive systems and carrier viewpoints

With the advent of the global and digital world, the number of geographically dispersed firms throughout the world has increased and the problem of Supply Chain (SC) disruption appeared as a main concern to many industries. In such context, designing disruptions management strategies for a robust SC has become a critical worldwide issue that is still under-explored. Since its design phase, this class of robust and global SC must integrate technologies and agents of production. However, the existing works only consider the Productive Systems (PSs) and the carrier viewpoint must also be considered since goods should be produced and distributed at the right quantity, at the right place and at the right time. In this complex task of designing disruptions management, a formal method must be used to integrate technologies ensuring the compliance of certain requirements, such as: developing collaborative and autonomous models, allowing reuse templates, considering analysis/simulation abilities and facilitating the interaction among engineering practitioners. Therefore, this paper presents a framework to model, analyse, control and monitor the robust and global SC, designing and integrating models with Petri Net, agent-based model techniques for disruptions management and considering both PSs and carrier viewpoints. A case study is investigated and the findings demonstrated the proposed solution supports decisions making for solving problems of design, analysis and control.
Gating Kinetics of Single Large-Conductance Ca 2 (cid:49) -activated K (cid:49) Channels in High Ca 2 (cid:49) Suggest a Two-Tiered Allosteric Gating Mechanism J

The Ca 2 (cid:49) -dependent gating mechanism of large-conductance calcium-activated K (cid:49) (BK) channels from cultured rat skeletal muscle was examined from low (4 (cid:109) M) to high (1,024 (cid:109) M) intracellular concentrations of calcium (Ca 2 (cid:49) i ) using single-channel recording. Open probability ( P o ) increased with increasing Ca 2 (cid:49) i ( K 0.5 11.2 (cid:54) 0.3 (cid:109) M at (cid:49) 30 mV, Hill coefﬁcient of 3.5 (cid:54) 0.3), reaching a maximum of (cid:122) 0.97 for Ca 2 (cid:49) i (cid:122) 100 (cid:109) M. Increasing Ca 2 (cid:49) i further to 1,024 (cid:109) M had little additional effect on either P o or the single-channel kinetics. The channels gated among at least three to four open and four to ﬁve closed states at high levels of Ca 2 (cid:49) i ( (cid:46) 100 (cid:109) M), compared with three to four open and ﬁve to seven closed states at lower Ca 2 (cid:49) i . The ability of kinetic schemes to account for the single-channel kinetics was examined with simultaneous maximum likelihood ﬁtting of two-dimensional (2-D) dwell-time distributions obtained from low to high Ca 2 (cid:49) i . Kinetic schemes drawn from the 10-state Monod-Wyman-Changeux model could not describe the dwell-time distributions from low to high Ca 2 (cid:49) i . Kinetic schemes drawn from Eigen’s general model for a ligand-activated tetrameric protein could approximate the dwell-time distributions but not the dependency (correlations) between adjacent intervals at high Ca 2 (cid:49) i . However, models drawn from a general 50 state two-tiered scheme, in which there were 25 closed states on the upper tier and 25 open states on the lower tier, could approximate both the dwell-time distributions and the dependency from low to high Ca 2 (cid:49) i . In the two-tiered model, the BK channel can open directly from each closed state, and a minimum of ﬁve open and ﬁve closed states are available for gating at any given Ca 2 (cid:49) i . A model that assumed that the apparent Ca 2 (cid:49) -binding steps can reach a maximum rate at high Ca 2 (cid:49) i could also approximate the gating from low to high Ca 2 (cid:49) i . The considered models can serve as working hypotheses for the gating of BK channels. Simple Models Fail to Predict the Single-Channel Kinetics at High Ca 2 (cid:49) i
Resilience Assessment and Its Enhancement in Tackling Adverse Impact of Ice Disasters for Power Transmission Systems

Ice disasters have frequently occurred worldwide in recent years, which seriously affected power transmission system operations. To improve the resilience of power grids and minimize economic losses, this paper proposes a framework for assessing the influence of ice disasters on the resilience of power transmission systems. This method considers the spatial–temporal impact of ice disasters on the resilience of power transmission systems, and the contingence set for risk assessment is established according to contingency probabilities. Based on meteorological data, the outage models of power transmission components are developed in the form of generic fragility curves, and the ice load is given by a simplified freezing rain ice model. A cell partition method is adopted to analyze the way ice disasters affect the operation of power transmission systems. The sequential Monte Carlo simulation method is used to assess resilience for capturing the stochastic impact of ice disasters and deriving the contingency set. Finally, the IEEE RTS-79 system is employed to investigate the impact of ice disasters by two case studies, which demonstrate the viability and effectiveness of the proposed framework. In turn, the results help recognize the resilience of the system under such disasters and the effects of different resilience enhancement measures.
Design of a Learing Input Shaping Technique for Suppressing Residual Vibration of an Industrial Robot

In this paper, a practical solution for suppressing residual vibrations of industrial robots is proposed. For suppressing the nonlinear and time-varying vibrations, we adopt learning input shaping technique (LIST), which is suitable for robots doing repetitive tasks. Through theoretical analyses and experiments, it is established that we can treat the MIMO dynamics of a robot as a set of decoupled S1S0 dynamics, making the application of LIST very practical. LIST is applied to a 6 DOF industrial robot intended for handling heavy payloads(up to 120 Kg) and experimented for both point-to-point motion and continuous path motion. Experimental results show that LIST can suppress residual vibrations to a level similar to that of time-varying input shaping technique, a much more sophisticated method, thereby demonstrating its potential for suppressing the residual vibrations in industrial robots.
A Review of Security and Privacy within Smart Cities - An Intrusion Detection Perspective

—Internet of Things (IoT) forms the foundation of next generation infrastructures, enabling development of future cities that are inherently sustainable. Intrusion detection for such paradigms is a non-trivial challenge which has attracted further signiﬁcance due to extraordinary growth in the volume and variety of security threats for such systems. However, due to unique characteristics of such systems i.e., battery power, bandwidth and processor overheads and network dynamics, intrusion detection for IoT is a challenge, which requires taking into account the trade-off between detection accuracy and performance overheads. In this context, we are focused at highlighting this trade-off and its signiﬁcance to achieve effective intrusion detection for IoT. Speciﬁcally, this paper presents a comprehensive study of existing intrusion detection systems for IoT systems in three aspects: computational overhead, energy consumption and privacy implications. Through extensive study of existing intrusion detection approaches, we have identiﬁed open challenges to achieve effective intrusion detection for IoT infrastructures. These include resource constraints, attack complexity, experimentation rigor and unavailability of relevant security data. Further, this paper is envisaged to highlight contributions and limitations of the state-of-the-art within intrusion detection for IoT, and aid the research community to advance it by identifying signiﬁcant research directions.
University of Birmingham Intake of α-linolenic acid and other fatty acids in relation to the risk of bladder cancer: results from the New Hampshire case–control study

The role of dietary fat in bladder cancer aetiology is currently unclear due to few studies, equivocal ﬁndings and a lack of information on important dietary fatty acids. The aim of the present study was to investigate the association between the intake of major dietary fats and fatty acids and the risk of bladder cancer. A case–control study was conducted in New Hampshire, USA. Dietary data were collected from 322 cases and 239 controls, and OR and 95% CI were calculated using unconditional logistic regression. Adjustment was made for potential confounders: sex, age, smoking status, pack-years smoked, cholesterol and energy intake. Statistically signiﬁcant reduced odds of bladder cancer were observed for high intakes (highest quartile v. lowest quartile) of a -linolenic acid (ALA) (OR 0·26, 95% CI 0·10, 0·65; P for trend ¼ 0·01) and vegetable fat (OR 0·39, 95% CI 0·18, 0·86; P for trend ¼ 0·03). Borderline statistically signiﬁcant reduced odds were detected for polyunsaturated fat (OR 0·43, 95% CI 0·19, 0·98; P for trend ¼ 0·07) and linoleic acid (OR 0·43, 95% CI 0·19, 0·96; P for trend ¼ 0·06). These fats and fatty acids were highly correlated and following adjustment for each other, the only potential inverse association to remain was for ALA. The present ﬁndings suggest that ALA may have a protective role against developing bladder cancer; however, further investigation and replication in other epidemiological studies are required. Future research should focus on the type, source and quantities of different dietary fatty acids consumed.
The analytics of product-design requirements using dynamic internet data: application to Chinese smartphone market

To accommodate the diverse users demands for consumer products, enterprises need to design and develop different lines of products according to different groups of users. Dynamic internet data, including product reviews, user attributes, and product configurations, are utilised to model users' stochastic product choice behaviours and mine the product design requirements of features, performance levels, and quantity. First, the web crawler is applied to collect internet data, and then the data are structured and the demand information is retrieved. Second, a product choice model is employed to capture the heterogeneity and correlation of user demands on product features. In particular, users' implicit requirements in terms of product function and performance are elicited from the text mining of product reviews. Third, incorporating various user requirements mined from dynamic internet data, graph theory analysis is introduced into design generation, product improvement, and market analysis. A case study on Chinese smartphones is presented, where the results show that the proposed method is practical and suitable for product-design analysis using the large volume of dynamic internet data.
Design of 8 × 8 dual‐band MIMO antenna array for 5G smartphone applications

A dual‐band 8 × 8 antenna array operating in the long term evolution (LTE) band 42 (3400‐3600 MHz) and LTE band 46 (5150‐5925 MHz) for 5G communication multi‐input multi‐output (MIMO) operation in the smartphone is presented. The proposed dual‐band antenna array element is composed of an L‐shaped open slot antenna and a U‐shaped monopole antenna. The measured results exhibited acceptable isolation (better than 12 dB) and good efficiency (more than 50%) across the two desired operation bandwidths. In addition to that, the proposed antenna array has also shown good MIMO performances with envelope correlation coefficient (ECC) lower than 0.1, and ergodic channel capacities higher than 38.8 bps/Hz in the operation bands. The hand phantom effects are also investigated, and the results show that the proposed antenna array can still exhibit good radiation and MIMO performances when operating under the single hand mode (SHM) and dual hands mode (DHM).
Control of Diurnal Variations in Photosynthetic Products

It has been demonstrated previously that the synthesis of amino acids from photosynthetically fixed carbon in leaves of Capsicumn annuum L. cv. California Wonder occurs in the mid-dle of the photoperiod. This paper reports experiments which identify control points regulating the carbon flow in these leaves.Estimations have been made of the levels of intermediates between 3-phosphoglycerate and pyruvate and between 3-phos-phoglycerate and fructose 6-phosphate in leaves at different times in the photoperiod. Application of the Chance crossover analysis indicates that during periods of amino acid synthesis, pyruvate kinase is activated, possibly by ammonium ions. Fructose diphosphate aldolase could possibly be an additional control point, showing activation when amino acid synthesis has ceased. There was no indication of diurnal periodicity in the activity of fructose diphosphate aldolase.