Miracle-dz/UniFAR-FTUs huggingface dataset:
Small-scale field assessment against the dengue vector Aedes aegypti using the auto-dissemination approach in an urban area of Vientiane, Lao PDR

Background In Lao PDR, dengue fever is the most important vector borne disease and vector control remains the principal method to fight against Aedes aegypti the primary transmitter mosquito species. Vector control management programs need new strategies in addition to conventional larviciding and adulticiding interventions in the country. In this study, we examined the In2Care® Mosquito Trap’s efficacy using insecticide auto-dissemination strategy. The insecticide pyriproxyfen, present in powder form inside the trap station, contaminates the body of gravid female mosquitoes visiting the traps and is later on disseminated via the mosquitoes in breeding sites surrounding the traps. We tested the attractiveness of the Traps, their efficacy to reduce the larval and adult abundance, and the impact on emergence rates. Specifically, we tested if the servicing interval of the In2Care® Mosquito Trap could be extended to 12 weeks. Methods Two black plastic ovitrap buckets and two BG® sentinel traps were placed in the premises of the Science campus of Vientiane Capital located in an urban area to measure weekly the larval and adult relative abundance of Aedes mosquitoes from 2017 to 2019. Twenty-five In2Care® Mosquito Traps were evenly distributed in this area and two studies of 12 weeks were implemented during January and April 2018 and, July to October 2018 (dry and rainy season, respectively). Every 2 weeks, water samples from 5 In2Care® Traps were randomly selected and tested at the laboratory with Ae. aegypti larvae to measure the larval and pupal mortality. The relative abundance of Aedes mosquitoes in the BG traps® with the presence of In2Care® Traps in 2018, was compared with the surveillance results obtained in 2017 and 2019 without In2Care® Traps. Every week, water samples from the ovitrap buckets were tested for Emergence Inhibition (EI). Results The In2Care® Traps were very attractive to gravid Ae. aegypti mosquitoes specifically during the rainy seasons with 96% of the traps colonized with larvae/pupae within four weeks. The bioassays showed 100% mortality in the water samples from the traps during the twelve weeks studies showing the good efficacy over time of the pyriproxyfen without additional servicing in the 12 week period. In addition, the larvicide was successfully disseminated into the ovitrap buckets placed in the treated area where 100% of EI during all weeks of intervention was measured. There was no significant effect of the treatment on adult abundance reduction in the treated area, probably due to recolonization of adult mosquitoes surrounding the field experiment. Conclusions The observed potential of the In2Care® Mosquito Trap using the auto-dissemination strategy could lead to the use of this new tool in combination with conventional control methods against Dengue vectors in urban tropical areas. Large scale field trials should be implemented in Lao PDR to prove its efficacy for Public Health programs.
Development of nurse-led videoconference-delivered cognitive behavioural therapy for domestic violence: Feasibility and acceptability.

AIMS Because of the COVID-19 lockdown, an internet-based adaption of a nurse-led cognitive behavioural group therapy (CGBT) was provided for perpetrators of domestic violence. The aim of this study was to describe the development of the therapy, examine the initial feasibility and impact on patient satisfaction of the programme and evaluate the associated patient-reported experiences. DESIGN Programme development as well as testing its feasibility and acceptability using cross-sectional survey data. METHODS Anonymous data were collected at a university hospital in Norway between October and December 2021. Feasibility was examined by comparing the numbers of patients who agreed to participate, chose not to participate or dropped out during the intervention. There was a self-reporting scale that evaluated patient satisfaction, and the participants were invited to make suggestions for improvement of the intervention. The results of the study are reported in accordance with the STROBE checklist. RESULTS The videoconference-delivered CGBT was feasible. Two of the 67 patients refused to attend therapy delivered in a remote manner (3.0%), and four patients (6.0%) were classified as non-completers. Overall, patients were satisfied with the therapy. CONCLUSIONS This study described a promising nurse-led internet-based intervention for individuals who were domestically violent and had voluntarily sought healthcare help. The participants' satisfaction with the intervention indicates its acceptability and feasibility. However, research on internet-based cognitive behaviour therapy is still in its infancy. These results may guide the future development of internet-based cognitive behavioural therapy (CBT) for individuals who perpetrate domestic violence. Further research is needed on the pros and cons of this mode of service delivery. IMPACT This study addressed the challenges of providing treatment for domestic violence during the COVID-19 pandemic by examining videoconference-delivered CBT for individuals who perpetrate domestic violence.
A Multiband Filter for Multistandards Wireless Communications Receivers

A new topology for a multiband filter suitable for multistandard and multiband mobile terminals is proposed. This filter named MultiCrossed Open Stubs (MCOS) is based on thewidebandQuarter-Wave Short Circuited Stubs (QWSCS) topology and consists of open stubs connected together with the main transmission line via a multicross junction. This technique allows division the wide bandpass response into several subbands by means of open stub transmission zeros. Full synthesis of the MCOS filter using ABCD matrices and its application to GSM, GPS, UMTS, LTE, and Wi-Fi standards using FR4 microstrip technology are presented. Scattering (S) parameters simulations and measurements show good agreement according to standard specifications in terms of center frequencies and bandwidths. The achievable return losses for all bands are higher than 10 dB, and transmission losses are between 3.9 dB and 6 dB. The proposed multiband filter topology is well suited for the implementation of reconfigurable multiband filters.
Evaluating the Quality of a Clinical Mobile App for Physicians' CT Scan Ordering Using the MARS Rating Scale

Given the lack of literature on the contributing factors to adopt mobile applications (apps) among physicians and the crucial role of the quality of the apps in their widespread use, the aim of this study is using the Mobile App Rating Scale (MARS) to evaluate the quality of the head CT scan appropriateness criteria app(HAC app). It was developed to assist medical interns and residents in ordering head CT scans. MARS is internationally recognized as an app rating tool and consists of four objective and subjective quality subscales quality subscale. Although the overall quality score of the HAC app was favorable (82 out of 100), it had low quality scores in the "information" (73.37 out of 100) and the "engagement" (73.48 out of 100) subscales. The HAC app appears to be functional to the physicians; however, it needs to improve its quality in terms of interactivity and effectiveness.
WPress: Benchmarking Infrastructure-as-a-Service cloud computing systems for on-line transaction processing applications

—Approaching a comprehensive performance bench- mark for on-line transaction processing (OLTP) applications in a cloud environment is a challenging task. Fundamental features of clouds, such as the pay-as-you-go pricing model and unknown underlying conﬁguration of the system, are contrary to the basic assumptions of available benchmarks such as TPC-W or RUBiS. In this paper, we introduce a systematic performance benchmark approach for OLTP applications on public clouds that use virtual machines (VMs). We propose WPress benchmark, which is based on the widespread blogging software, WordPress, as a representative OLTP application and implement an open source workload generator. Furthermore, we utilize a CPU micro-benchmark to investigate CPU performance of cloud-based VMs in greater detail. Average response time and total VM cost are the performance metrics measured by WPress . We evaluate small and large instance types of three real-life cloud providers, Amazon EC2, Microsoft Azure and Rackspace cloud. Results imply that Rackspace cloud has better average response times and total VM cost on small instances. However, Microsoft Azure is preferable for large instance type.
Epigallocatechin-3-gallate ameliorates renal endoplasmic reticulum stress-mediated inflammation in type 2 diabetic rats

Epigallocatechin-3-gallate (EGCG), an essential polyphenolic constituent found in tea leaves, possesses various potent biological activities. This research was undertaken to investigate the impact of EGCG against endoplasmic reticulum (ER) stress-mediated inflammation and to clarify the underlying molecular mechanism in type 2 diabetic kidneys. The male rats were randomized into four groups: normal, diabetic, low-dose EGCG, and high-dose EGCG. In type 2 diabetic rats, hyperglycemia and hyperlipidemia noticeably caused renal structural damage and dysfunction and aggravated ER stress. Meanwhile, sustained ER stress activated the NOD-like receptor family pyrin domain containing 3 (NLRP3) inflammasome and then upregulated the contents of inflammatory cytokines in the diabetic kidney. Following supplementation with 40 mg/kg and 80 mg/kg EGCG, hyperglycemia, hyperlipidemia, and renal histopathological alterations and dysfunction were noticeably ameliorated; renal ER stress, NLRP3 inflammasome, and inflammatory response were markedly repressed in the EGCG treatment groups. In summary, the current study highlighted the renoprotective effects of EGCG in type 2 diabetes and its mechanisms are mainly associated with the repression of ER stress-mediated NLRP3 inflammasome overactivation.
Abnormal larval neuromuscular junction morphology and physiology in Drosophila prickle isoform mutants with known axonal transport defects and adult seizure behavior

Abstract Previous studies have demonstrated the striking mutational effects of the Drosophila planar cell polarity gene prickle (pk) on larval motor axon microtubule-mediated vesicular transport and on adult epileptic behavior associated with neuronal circuit hyperexcitability. Mutant alleles of the prickle-prickle (pkpk ) and prickle-spiny-legs (pksple ) isoforms (hereafter referred to as pk and sple alleles, respectively) exhibit differential phenotypes. While both pk and sple affect larval motor axon transport, only sple confers motor circuit and behavior hyperexcitability. However, mutations in the two isoforms apparently counteract to ameliorate adult motor circuit and behavioral hyperexcitability in heteroallelic pkpk/pkspl e flies. We have further investigated the consequences of altered axonal transport in the development and function of the larval neuromuscular junction (NMJ). We uncovered robust dominant phenotypes in both pk and sple alleles, including synaptic terminal overgrowth (as revealed by anti-HRP and -Dlg immunostaining) and poor vesicle release synchronicity (as indicated by synaptic bouton focal recording). However, we observed recessive alteration of synaptic transmission only in pk/pk larvae, i.e. increased excitatory junctional potential (EJP) amplitude in pk/pk but not in pk/+ or sple/sple. Interestingly, for motor terminal excitability sustained by presynaptic Ca2+ channels, both pk and sple exerted strong effects to produce prolonged depolarization. Notably, only sple acted dominantly whereas pk/+ appeared normal, but was able to suppress the sple phenotypes, i.e. pk/sple appeared normal. Our observations contrast the differential roles of the pk and sple isoforms and highlight their distinct, variable phenotypic expression in the various structural and functional aspects of the larval NMJ.
Earthen mortars in Cremona: characterization and first hypothesis of dating

Historic buildings in Cremona are characterized by the almost exclusive use of earthen mortars, also for plasters. The use of earthen mortars was a conscious choice and the masonry structures are of very good quality. The thickness of the walls is considerable, at least four heads of bricks, their tissue is regular from the front to the back of the wall. Their resistance to compression has shown results similar to those of walls of the same period constructed with lime based mortar. Preliminary data of the archaeometric study reveal the compositional and microstructural complexity of the earthen mortars. The properties of some clay minerals to absorb water may be useful in many respects in a climate where the relative humidity is high. The empirical knowledge would allow the exploitation of a country resource.
The Achilles’ heel of cancer survivors: fundamentals of accelerated cellular senescence

Recent improvements in cancer treatment have increased the lifespan of pediatric and adult cancer survivors. However, cancer treatments accelerate aging in survivors, which manifests clinically as the premature onset of chronic diseases, such as endocrinopathies, osteoporosis, cardiac dysfunction, subsequent cancers, and geriatric syndromes of frailty, among others. Therefore, cancer treatment–induced early aging accounts for significant morbidity, mortality, and health expenditures among cancer survivors. One major mechanism driving this accelerated aging is cellular senescence; cancer treatments induce cellular senescence in tumor cells and in normal, nontumor tissue, thereby helping mediate the onset of several chronic diseases. Studies on clinical monitoring and therapeutic targeting of cellular senescence have made considerable progress in recent years. Large-scale clinical trials are currently evaluating senotherapeutic drugs, which inhibit or eliminate senescent cells to ameliorate cancer treatment–related aging. In this article, we survey the recent literature on phenotypes and mechanisms of aging in cancer survivors and provide an up-to-date review of the major preclinical and translational evidence on cellular senescence as a mechanism of accelerated aging in cancer survivors, as well as insight into the potential of senotherapeutic drugs. However, only with time will the clinical effect of senotherapies on cancer survivors be visible.
Kinesiophobia and self‐management behaviour related to physical activity in Chinese patients with coronary heart disease: The mediating role of self‐efficacy

The purpose of this study was to explore the relationship among kinesiophobia, self‐efficacy and self‐management behaviour related to physical activity (SMBPA) in Chinese patients with coronary heart disease(CHD) and the mediating role of self‐efficacy between kinesiophobia and SMBPA in Chinese patients with CHD.
Contextualising Translator Training: Defining Social, Professional and Disciplinary Requirements

Abstract In order to adapt universities to the social, disciplinary and professional needs, we consider it necessary to contextualise the professional profiles of translators. The main groups involved in the educational process are translation teachers and researchers, employers and students/graduates, and their contribution to the definition of professional profiles is essential. Therefore, in this article we will focus on studies about professional profiles from the following perspectives: translation market studies, academic research, research on labour market insertion and students’ expectations. These studies will allow us to draw conclusions that could be applied during curricular design.
Assessment of Right Ventricle by Echocardiogram Assessment of Right Ventricle by Echocardiogram

Assessment of right ventricular (RV) function is important to ascertain clinical outcome in patients with symptoms of right ventricular failure manifested as lower extremity swelling and abdominal congestion. RV function is not routinely assessed and reported in clinical practice. Unlike the bullet‐shaped left ventricle (LV), RV has a complex geometry with a triangular shape. RV is further divided into the inlet, trabecular apex, and infundibulum or conus. RV evaluation involves quantifying afterload and preload, assessing the mechanism and severity of tricuspid regurgitation (TR), and quantitative evaluation of RV performance. For quantification of RV size and function, we can use intravenous contrast for endocardial tracing of RV border to measure RV dimensions, tricuspid annular plane systolic excursion (TAPSE), fractional area change (FAC), Doppler index of myocardial performance (Tei index or myocardial performance index), pulsed wave or color Doppler tissue imaging systolic velocity [s'], or strain imaging. For qualitative evaluation of RV, the RV size is compared to the LV size in parasternal, short axis, and subcostal projections.
Cognitive and behavioral abnormalities in children after hematopoietic stem cell transplantation for severe congenital immunodeﬁciencies

Hematopoietic stem cell transplantation is a highly successful treatment for severe congenital immunodeﬁciencies. and emotional and behavioral of the of P of combined at Children treated by HSCT for severe immunodeﬁciency have an increased risk of long-term cognitive difﬁculties and associated emotional and behavioral difﬁculties. The speciﬁc genetic diagnosis, consanguinity, and severe clinical course are associated with poor outcome. Long-term follow-up of these patients should include screening to identify and manage these problems more effectively. (Blood. 2008;112: 3907-3913)
Time domain electromagnetic‐induced polarisation: extracting more induced polarisation information from grounded source time domain electromagnetic data

Electrical induced polarisation surveys are used to detect chargeable materials in the earth. For interpretation of time domain electrical‐induced polarisation data a common procedure is to first invert the direct current data (electric current on time) to recover conductivity and then invert the induced polarisation data (current off‐time) to recover chargeability. This direct current‐induced polarisation inversion procedure assumes that the off time data are free of secondary electromagnetic induction effects. To comply with this, early time data are often discarded or not recorded. For mid‐time data, an electromagnetic decoupling technique, which removes electromagnetic induction in the observations, needs to be implemented. Usually, responses from a half‐space or a layered earth are subtracted. Recent capability in three‐dimensional time domain electromagnetic forward modelling and inversion allows to revisit these procedures. In a Time domain electromagnetic‐induced polarisation survey, a high sampling rate allows early time channels of the electromagnetic data to be recorded. The recovery of chargeability then follows a three‐step workflow: (i) invert early time channel time domain electromagnetic data to recover the three‐dimensional conductivity; (ii) use that conductivity to compute the time domain electromagnetic response at later time channels and subtract this fundamental response from the observations to extract the induced polarisation responses, and (iii) invert the induced polarisation responses to recover a three‐dimensional chargeability. This workflow effectively removes electromagnetic induction effects in the observations and produces better chargeability and conductivity models compared with conventional approaches. In a synthetic example involving a gradient array, we show that the conductivity structure obtained from the early time channel data, which are usually discarded, is superior to that obtained from the steady state direct current voltages. This adds a further reason to collect these electromagnetic data.
The Effectiveness of a Mindfulness-Based Psychoeducation Programme for Emotional Regulation in Individuals with Schizophrenia Spectrum Disorders: A Pilot Randomised Controlled Trial Neuropsychiatric

Background: Emotion dysregulation has emerged as a transdiagnostic factor that poten-tially exacerbates the risk of early-onset, maintenance, and relapse of psychosis. Mindfulness is described as the awareness that emerges from paying attention to the present moment without judgment. It gently pulls the mind out of the negative emotions induced by the disparity between expectation and reality by focusing on the present moment, instead of worrying about the future or regretting the past. However, only a few research has ever focused on the ef ﬁ cacy of using a mindfulness-based intervention to improve emotion regulation in schizophrenia spectrum disorders. Purpose: The purpose of this study was to examine the effectiveness of a Mindfulness-Based Psychoeducation Programme (MBPP) on the emotion regulation of individuals with schizophrenia, in particular, to access emotion regulation strategies. The objective of this study was to ﬁ nd out whether MBPP is feasible for improving emotion regulation strategies, in terms of rumination, cognitive reappraisal, and expressive suppression, with a sustainable effect at a three-month follow-up. Patients and Methods: A single-blinded pilot randomised controlled trial with repeated-measures designs was adopted. Forty-six participants diagnosed with schizophrenia and its subtypes were randomised in either the 8-week mindfulness-based psychoeducation programme or treatment-as-usual (control) group. Results: The results of the Generalised Estimating Equations test indicated that the MBPP group showed a signi ﬁ cant improvement in reappraisal at a three-month follow-up ( β = − 6.59, Wald ’ s χ 2 =4.55, p=0.033), and a signi ﬁ cant reduction in rumination across time. However, the Generalised Estimating Equations indicated no signi ﬁ cant difference in rumination and expressive suppression in the MBPP group. Two participants reported having unwanted experiences, including feelings of terror and distress during the mindfulness practice. Conclusion: The MBPP appeared to be effective for improving emotion regulation, which will contribute to future large-scale RCT to con ﬁ rm the treatment effects in more diverse groups of schizophrenic patients.
Business Intelligence using Semantic Web

: Computers have become an essential thing in our day-to-day life. Currently, computers have changed from single, isolated devices to entry points in order to exchange information on the World Wide Web (WWW). Human beings are capable of using the web to carry out a task. However, a computer cannot accomplish the same task without the human direction, because web pages are designed to be read by the people, not by the machines. Usually, human beings interact with the web to gather information or to improve their business intelligence. The information is accessed by giving a related keyword to search. This keyword is used by the server to provide the relevant information. The server provides only limited information for the given keyword. But there exists a lot of information but it is not provided to the user due to the lack of words in the given keyword. So searching becomes intangible to fulfill the requirements of the user in some situation. This kind of searching is made with the presence of human beings. To overcome this problem and to reduce the human effort, a new method is employed in this paper. This new method is termed as “ SEMANTIC WEB ”.