Miracle-dz/UniFAR-FTUs huggingface dataset:
MGAN: TRAINING GENERATIVE ADVERSARIAL NETS

We propose in this paper a new approach to train the Generative Adversarial Nets (GANs) with a mixture of generators to overcome the mode collapsing problem. The main intuition is to employ multiple generators, instead of using a single one as in the original GAN. The idea is simple, yet proven to be extremely effective at covering diverse data modes, easily overcoming the mode collapsing problem and delivering state-of-the-art results. A minimax formulation was able to establish among a classifier, a discriminator, and a set of generators in a similar spirit with GAN. Generators create samples that are intended to come from the same distribution as the training data, whilst the discriminator determines whether samples are true data or generated by generators, and the classifier specifies which generator a sample comes from. The distinguishing feature is that internal samples are created from multiple generators, and then one of them will be randomly selected as final output similar to the mechanism of a probabilistic mixture model. We term our method Mixture Generative Adversarial Nets (MGAN). We develop theoretical analysis to prove that, at the equilibrium, the Jensen-Shannon divergence (JSD) between the mixture of generators’ distributions and the empirical data distribution is minimal, whilst the JSD among generators’ distributions is maximal, hence effectively avoiding the mode collapsing problem. By utilizing parameter sharing, our proposed model adds minimal computational cost to the standard GAN, and thus can also efficiently scale to large-scale datasets. We conduct extensive experiments on synthetic 2D data and natural image databases (CIFAR-10, STL-10 and ImageNet) to demonstrate the superior performance of our MGAN in achieving state-of-the-art Inception scores over latest baselines, generating diverse and appealing recognizable objects at different resolutions, and specializing in capturing different types of objects by the generators.
A Lifted Compact Formulation for the Daily Aircraft Maintenance Routing Problem

Given a set of flights for a specific fleet type, the aircraft routing problem (ARP) determines the flying sequence for each individual aircraft while incorporating specific considerations of minimum turn time, maintenance checks, as well as restrictions on the total accumulated flying time, the total number of takeoffs, and the total number of days between two consecutive maintenances. This stage is significant to airline companies as it directly assigns operational routes and maintenance breaks for each aircraft in service. Most approaches related to the problem adopt set partitioning formulations that include exponentially many variables, which requires the design of specialized column generation or branch-and-price algorithms and codes. In this paper, we present a compact polynomial-sized representation for the ARP, which is then linearized and lifted using the reformulation-linearization technique. In addition, we propose two root-node strategies for further augmenting the model formulation. The resulting formulations remain polynomial in size, and we show that they can be solved very efficiently by commercial software without complicated algorithmic implementations. The numerical experiments demonstrate high-quality solutions and significant savings in computational time.
Exploiting Physical Dynamics to Detect Actuator and Sensor Attacks in Mobile Robots

Mobile robots are cyber-physical systems where the cyberspace and the physical world are strongly coupled. Attacks against mobile robots can transcend cyber defenses and escalate into disastrous consequences in the physical world. In this paper, we focus on the detection of active attacks that are capable of directly influencing robot mission operation. Through leveraging physical dynamics of mobile robots, we develop RIDS, a novel robot intrusion detection system that can detect actuator attacks as well as sensor attacks for nonlinear mobile robots subject to stochastic noises. We implement and evaluate a RIDS on Khepera mobile robot against concrete attack scenarios via various attack channels including signal interference, sensor spoofing, logic bomb, and physical damage. Evaluation of 20 experiments shows that the averages of false positive rates and false negative rates are both below 1%. Average detection delay for each attack remains within 0.40s.
Output voltage effects in a 2/spl times/2 SMC caused by time index change

A stacked multicell converter (SMC) is an inverter specially adapted to high voltage applications. This inverter is composed of commutation cells ordered in p rows and n stacks, reducing semiconductor commutation stresses and high operation frequencies can be reached. This structure requires 2(pxn) switches to generate an output signal similar to a sinusoidal waveform. However, the switches must be correctly controlled. The most commonly used control technique has been the typical PWM. However, it is possible to generate a control scheme by FPGA technology. So, the control signals are established by the designer. This kind of control has been called patron control signals. In this paper, a complete mathematical analysis of the output voltage behavior for a 2/spl times/2 SMC, when the time index (/spl beta/) changes, is presented. In addition, simulation results are shown to validate the mathematical analysis.
Stochastic Constraint Programming for General Game Playing with Imperfect Information

The game description language with incomplete information (GDL-II) is expressive enough to capture partially observable stochastic multi-agent games. Unfortunately, such expressiveness does not come without a price: the problem of finding a winning strategy is NEXPNP-hard, a complexity class which is far beyond the reach of modern constraint solvers. In this paper, we identify a PSPACE-complete fragment of GDL-II, where agents share the same (partial) observations. We show that this fragment can be cast as a decomposable stochastic constraint satisfaction problem (SCSP) which, in turn, can be solved using general-purpose constraint programming techniques. Namely, we develop a constraint-based sequential decision algorithm for GDL-II games which exploits constraint propagation and Monte Carlo sampling based. Our algorithm, validated on a wide variety of games, significantly outperforms the state-of-the-art general game playing algorithms.
FIXED DYSTONIA UNRESPONSIVE TO PALLIDAL STIMULATION IMPROVED BY MOTOR CORTEX STIMULATION

neither designed nor powered to detect a reduction in all-cause mortality. The previously cited meta-analysis (primarily reflecting trials of patients without prior stroke) found no difference in hemorrhagic stroke associated with statin treatment (RR 1.05, 99% CI 0.78 to1.41; p 0.7). 3 The purposes of my editorial comment4 were to both put Dr. Bang and colleagues’ observational study into perspective and to prompt thoughtful consideration of the potential relationship between recanalization therapy, low cholesterol, and the risk of hemorrhagic infarction. Statin treatment can be associated with an overall reduction in stroke in both primary and secondary prevention populations. Fewer patients having strokes will result in fewer needing emergent recanalization. The potential for statin-related side effects should not be minimized, but needs to be balanced by the benefit of the treatment. Larry B. Goldstein, Durham, NC
Nanotip analysis for dielectrophoretic concentration of nanosized viral particles

Rapid and sensitive detection of low-abundance viral particles is strongly demanded in health care, environmental control, military defense, and homeland security. Current detection methods, however, lack either assay speed or sensitivity, mainly due to the nanosized viral particles. In this paper, we compare a dendritic, multi-terminal nanotip (‘dendritic nanotip’) with a single terminal nanotip (‘single nanotip’) for dielectrophoretic (DEP) concentration of viral particles. The numerical computation studies the concentration efficiency of viral particles ranging from 25 to 100 nm in radius for both nanotips. With DEP and Brownian motion considered, when the particle radius decreases by two times, the concentration time for both nanotips increases by 4–5 times. In the computational study, a dendritic nanotip shows about 1.5 times faster concentration than a single nanotip for the viral particles because the dendritic structure increases the DEP-effective area to overcome the Brownian motion. For the qualitative support of the numerical results, the comparison experiment of a dendritic nanotip and a single nanotip is conducted. Under 1 min of concentration time, a dendritic nanotip shows a higher sensitivity than a single nanotip. When the concentration time is 5 min, the sensitivity of a dendritic nanotip for T7 phage is 104 particles ml−1. The dendritic nanotip-based concentrator has the potential for rapid identification of viral particles.
Connectivity of the tectal zones coding for upward and downward oblique eye movements in goldfish

Deep layers of the goldfish tectum code movements in a topographically ordered motor map. This work studies the relationship between tectal sites (coding eye movements with different vertical directions) and the distributions of boutons (left by their projections), within rostral mesencephalic structures and rhombencephalic reticular formations. These regions have been involved in the generation of the vertical and horizontal components of eye movement, respectively, as suggested by the Cartesian hypothesis of de‐codification of tectal signal. With this aim, discrete injections of biotinylated dextran amine (BDA) and Fluoro‐Ruby (FR) were made into functionally identified tectal sites, coding oblique eye movements with similar amplitude of the horizontal component but opposite upward and downward vertical directions, and the distribution of synaptic endings was determined. The main findings of the present work were as follows: 1) within the tectal descending tract, axons were organized according to the location of injected sites within the tectum; 2) BDA and FR boutons were distributed in separate clusters within the medial longitudinal fasciculus and oculomotor nuclei, as well as in the nearby mesencephalic reticular formation; and 3) the regions containing both types of bouton overlapped moderately within the mesencephalic reticular formation at the isthmus level. Overlapping was more extended at the different levels of the rhombencephalic reticular formation, although a shift in the distribution of both types of bouton was always observed. These results suggest that, within the vertical generator, the endings were separated to contact the different neuronal population that codes the upward and downward components of movements. In contrast, in the horizontal generator, tectal endings more likely converge on the same neuronal population to code the horizontal component of movements, irrespective of whether the oblique movements were directed upward or downward. J. Comp. Neurol. 427:405–416, 2000. © 2000 Wiley‐Liss, Inc.
Expression and methylation analysis of p15 and p16 in mouse bone marrow cells exposed to 1,4-benzoquinone

Benzene is an important industrial chemical. It is also an environmental pollutant recognized as a human carcinogen. Both prenatal and adult exposures to benzene are associated with the development of leukemia. To understand the mechanism of benzene-induced epigenetic variations, we investigated the expression and methylation patterns of CpG (phosphodiester bond between cytosine and guanine) islands in p15 and p16 promoter regions in 1,4-benzoquinone (1,4-BQ)-treated primary cultivated C57BL/6J mouse bone marrow cells in vitro. The cell toxicity of 1,4-BQ was evaluated by cell viability test, real-time PCR was used to measure the mRNA expression levels, and bisulfite sequencing PCR (BSP) was used to look into the methylation patterns. The cell viability test indicates that 1,4-BQ exhibited a dose-dependent toxicity to mouse bone marrow cells. After a 24-h exposure to 1,4-BQ at final concentrations of 0, 0.1, 1, and 10 μmol/L, the mRNA expression of p15 and p16 decreased with the increase in 1,4-BQ concentration. The BSP results gathered from the exposure and the control groups were the same. In summary, despite the observation that short-term exposure to 1,4-BQ primary cultivated mouse bone marrow cells decreased the p15 and p16 transcripts, with no influence by their gene promoter methylation.
Effects of the dietary amount and source of protein, resistance training and anabolic-androgenic steroids on body weight and lipid profile of rats.

INTRODUCTION Dietary protein amount and source, hypertrophy resistance training (RT) and anabolicandrogenic steroids (AAS) may affect body weight and plasma and hepatic lipid profile. MATERIAL AND METHODS 157 adult male Wistar rats were randomly distributed in 16 experimental groups resulting in: normal-protein (NP) or high-protein (HP) diets, whey or soy-protein diets, with or without RT and with or without AAS, for 3 months. RESULTS AND DISCUSSION Final body weight was lower in the RT and AAS groups compared to sedentary and non- AAS groups, respectively (all, p<0.001). Plasma total cholesterol (TC) was lower for the HP compared to the NP diets, for the whey compared to the soy-protein diets and for the AAS compared to the non-AAS groups (all, p<0.001). Plasma HDL-cholesterol was higher in the RT groups (p<0.05) but lower for the AAS groups (p<0.001), the HP and the soy-protein diets (p<0.05). Plasma triglycerides (TAG) were lower for the HP diet (p<0.001), for the RT (p=0.002) and the non-AAS groups (p=0.001). Liver TC was lower for the NP (p<0.01), for the soyprotein (p<0.05) and for the AAS groups (p<0.001). Liver TAG were lower for the whey-protein diet (p<0.001), RT and non-AAS groups (both, p<0.05). Some interactions were found, such as the greater effect of AAS on reducing body weight of rats that performed RT or ingested a HP diet (all, p<0.05). HDL-cholesterol was higher when RT was combined with HP diets (p=0.010) or non-AAS and when HP diets were combined with non-AAS (both,p<0.001). Groups that combined RT with non-AAS administration obtained the lowest hepatic TAG (p<0.05). CONCLUSION Among all the interventions tested, AAS was the factor that most negatively affected plasma and hepatic lipid profile, whereas HP diets and RT could benefit lipid profile, especially when combined.
Cognitive function and brain structure in persons with type 2 diabetes mellitus after intensive lowering of blood pressure and lipid levels: a randomized clinical trial.

IMPORTANCE Persons with type 2 diabetes mellitus (T2DM) are at increased risk for decline in cognitive function, reduced brain volume, and increased white matter lesions in the brain. Poor control of blood pressure (BP) and lipid levels are risk factors for T2DM-related cognitive decline, but the effect of intensive treatment on brain function and structure is unknown. OBJECTIVE To examine whether intensive therapy for hypertension and combination therapy with a statin plus a fibrate reduces the risk of decline in cognitive function and total brain volume (TBV) in patients with T2DM. DESIGN, SETTING, AND PARTICIPANTS A North American multicenter clinical trial including 2977 participants without baseline clinical evidence of cognitive impairment or dementia and with hemoglobin A1c (HbA1c) levels less than 7.5% randomized to a systolic BP goal of less than 120 vs less than 140 mm Hg (n = 1439) or to a fibrate vs placebo in patients with low-density lipoprotein cholesterol levels less than 100 mg/dL (n = 1538). Participants were recruited from August 1, 2003, through October 31, 2005, with the final follow-up visit by June 30, 2009. MAIN OUTCOME MEASURES Cognition was assessed at baseline and 20 and 40 months. A subset of 503 participants underwent baseline and 40-month brain magnetic resonance imaging to assess for change in TBV and other structural measures of brain health. RESULTS Baseline mean HbA1c level was 8.3%; mean age, 62 years; and mean duration of T2DM, 10 years. At 40 months, no differences in cognitive function were found in the intensive BP-lowering trial or in the fibrate trial. At 40 months, TBV had declined more in the intensive vs standard BP-lowering group (difference, -4.4 [95% CI, -7.8 to -1.1] cm(3); P = . 01). Fibrate therapy had no effect on TBV compared with placebo. CONCLUSIONS AND RELEVANCE In participants with long-standing T2DM and at high risk for cardiovascular events, intensive BP control and fibrate therapy in the presence of controlled low-density lipoprotein cholesterol levels did not produce a measurable effect on cognitive decline at 40 months of follow-up. Intensive BP control was associated with greater decline in TBV at 40 months relative to standard therapy. TRIAL REGISTRATION clinicaltrials.gov Identifier: NCT00000620.
Business process-based modeling of enterprise communication network

Communications in organizations have been one of the most important issues. To run the business processes, the company needs communication between units and customers. We provide a framework which can be used by network designers in an organization. The outcome of the framework is value for three QoS parameters: delay, loss and availability. The organizations business processes are used as a basis for the framework We used UML as the tool to model the business processes in the organization. First, the process is modeled with UML activity, sequence and class diagrams. Then, a three-step analysis has been conducted on the models to find the specifications of the business process. The analysis covers the data, actors and time domains in the business process. The framework assumes that the business processes are static and no change happens during the work of information systems.
Measurement of Gd-DTPA diffusion through PVA hydrogel using a novel magnetic resonance imaging method.

Polyvinyl alcohol-cryogel (PVA-C) is a hydrogel that is an excellent tissue mimic. In order to characterize mass transfer in this material, as well as to demonstrate in principle the ability to noninvasively measure solute diffusion in tissue, we measured the diffusion coefficient of the magnetic resonance (MR) contrast agent gadolinium diethylene triaminopentaacetic acid (Gd-DTPA) through PVA-C using a clinical MR imager. The method involved filling thick-walled rectangular PVA-C "cups" with known concentrations of Gd-DTPA solutions. Then by using a fast inversion recovery spin echo MR imaging protocol, a signal "null" contour was created in the MR image that corresponded to a second, known concentration of Gd-DTPA. By collecting a series of MR images through the PVA-C wall as a function of time, the displacement of this second known isoconcentration contour could be tracked. Application of Fick's second law of diffusion yielded the diffusion coefficient. Seven separate experiments were performed using various combinations of initial concentrations of Gd-DTPA within the PVA-C cups (3.2, 25.6, or 125 mM) and tracked isoconcentrations contours (0.096, 0.182, or 0.435 mM Gd-DTPA). The experimental results and the predictions of Fick's law were in excellent agreement. The diffusivity of Gd-DTPA through 10% PVA hydrogel was found to be (2.6 +/- 0.04) x 10(-10) m(2)/s (mean +/- s.e.m.). Separate permeability studies showed that the diffusion coefficient of Gd-DTPA through this hydrogel did not change with an applied pressure of up to 7.1 kPa. Accurate measurements could be made within 30 min if suitable Gd-DTPA concentrations were selected. Due to the excellent repeatability and fast data acquisition time, this technique is very promising for future in vivo studies of species transport in tissue.
A parallel algorithm for tree pattern matching

Given a text tree t and a pattern tree p, tree pattern matching involves finding subtrees of t which match p. This paper proposed a parallel algorithm for tree pattern matching. The algorithm is designed to run in O(log n) parallel time using mn/logn processors on CREW-PRAM, where n and m are the sizes of t and p respectively. This improves the result of Ramesh et al. that runs in O(log 2 n) time using nr/log 2 n processors, where r is the number of vertices of p labeled with variables. Futhermore, the method of processor allocation is described specifically in the proposed algorithm
Controlling Thermal Conductivity of Alloys via Atomic Ordering

Many random substitutional solid solutions (alloys) will display a tendency to atomically order given the appropriate kinetic and thermodynamic conditions. Such order–disorder transitions will result in major crystallographic reconfigurations, where the atomic basis, symmetry, and periodicity of the alloy change dramatically. Consequently, phonon behavior in these alloys will vary greatly depending on the type and degree of ordering achieved. To investigate these phenomena, the role of the order–disorder transition on phononic transport properties of Lennard–Jones type binary alloys is explored via nonequilibrium molecular dynamics simulations. Particular attention is paid to regimes in which the alloy is only partially ordered. It is shown that by varying the degree of ordering, the thermal conductivity of a binary alloy of fixed composition can be tuned across an order of magnitude at 10% of the melt temperature, and by a factor of three at 40% of the melt temperature.
Molecular dynamics studies on structure and dynamics of phospholamban monomer and pentamer in membranes

Phospholamban (PLB) is an integral membrane protein of 52 residues that regulates the activity of the sarcoplasmic reticulum calcium pump in cardiac muscle cells through reversible phosphorylation of Ser16. To explore its possible conformations and dynamics in a monomeric state, we have performed comparative molecular dynamics simulations of unphosphorylated and phosphorylated PLB (pPLB) with various orientations in POPC membranes. The simulations indicate that dynamics of the cytoplasmic domain is highly dependent on its interactions with membranes, that is, large conformational changes in the absence of membrane interactions, but very restricted dynamics in their presence. pPLB shows more structural flexibility in its cytoplasmic domain, which is consistent with experimental observations. We have also performed a simulation of a PLB pentameric structure (the so‐called bellflower model), recently determined in micelles, to investigate its behaviors in a POPC membrane. The cytoplasmic domain in each monomer shows uncorrelated dynamics and undergoes large conformational changes toward the membrane surface during the simulation, which supports the so‐called pinwheel model of the PLB pentamer structure. The hydrophobic nature of the pentameric pore excludes water molecules in the pore region, which illustrates that the pore appears to be an energetic barrier for ion and water translocation. Proteins 2009. © 2008 Wiley‐Liss, Inc.