Miracle-dz/UniFAR-FTUs huggingface dataset:
EFFICACY AND TOLERABILITY OF RISPERIDONE IN THE TREATMENT OF DEPRESSIVE DISORDERS

The aim of this paper was to assess the efficacy and the tolerability of the therapy with risperidone in the case of depressive disorders. 84 adult subjects aged 18-65 years were randomized into two groups: 42 patients into lot A treated with risperidone (12mg/day) and 42 subjects lot B, placebo. Symptoms were measured using the 17-item Hamilton Rating Scale for Depression (HRSD-17). Other outcomes were the response to therapy, and the adverse events. Mean HRSD-17 scores improved more in the risperidone group than in the placebo group. Headache (19.04% of risperidone group vs. 26.19% of placebo group), somnolence (16.67% vs. 4.76%), dry mouth (9.52% vs. 7.14%), nausea (4.76% vs.11.91%) and weight gain (14.28% vs. 7.14%) were the most frequently reported adverse events. Risperidone produced significant reduction in depression symptoms having a good tolerability.
Implementing systems in complex work organisations

This paper describes research on a case of the introduction, into a large educational institution, of a complex timetabling system that was already well established in other similar organisations. The research has used a grounded theory approach to reveal details within complex phenomena in an organisation when a substantial new system was implemented. The study revealed three critical issues: Knowledge Transfer, System Capability, and Organisational Context that appeared to be related to the problems of implementing the new information system in the organisation. This research adds to the understanding of a common situation where management have an over simplified view of organisational work and assume that implementing a new computer based system can quite easily improve the performance of the organisation.
Youth unemployment in Europe: appraisal and policy options

The alarming rise of youth unemployment rates following the recent economic turmoil has challenged national as well as European labour market policies. With more than 5.5 million young people in the [European Union] EU struggling to find jobs, there is an urgent need to develop strategies for combating youth unemployment, in order to avoid a lost generation of European youths threatened by lasting disadvantages in terms of labour market and social position. This study's aims are to survey the development of youth unemployment in Europe, to identify the relevant institutional and economic drivers and to discuss the necessary courses of action to achieve a better integration of young adults into the labour market. While the study covers the perspective of the EU member states as a whole, it strongly focuses on southern European countries, which are especially suffering from the current youth unemployment crisis. Its core part is comprised of three country reports which detail the situation in Italy, Spain and Portugal, and review current and potential future policy initiatives that could help in reducing youth unemployment.
The role of personal values in behavioural-based safety: Evidence from UK & Thailand inquiries

Whilst behavioural-based safety (BBS) is not new and even becoming increasingly common especially among large construction organisations, research on BBS is yet to explore the potential effect of innate triggers of behaviour such as personal values. This study addresses this gap, by presenting findings from two exploratory surveys (in UK & Thailand) into the influence of workers' personal values on occupational safety and health behaviour (OSHB). Data analysis, revealed from both surveys that higher-order dimensions of personal values have statistically significant relationships with OSHB. For instance, in the Thai study, conservation was positively related to occupational safety and health (OSH) participation, while in the UK survey, self-transcendence was also positively related to OSH compliance. Overall, the findings from the different national contexts provide some evidence of the predictive influence of personal values on OSHB. The research outcomes therefore highlight the significance of workers' personal values to BBS.
Algebraic deformations of toric varieties II. Noncommutative instantons

We continue our study of the noncommutative algebraic and differential geometry of a particular class of deformations of toric varieties, focusing on aspects pertinent to the construction and enumeration of noncommutative instantons on these varieties. We develop a noncommutative version of twistor theory, which introduces a new example of a noncommutative four-sphere. We develop a braided version of the ADHM construction and show that it parametrizes a certain moduli space of framed torsion free sheaves on a noncommutative projective plane. We use these constructions to explicitly build instanton gauge bundles with canonical connections on the noncommutative four-sphere that satisfy appropriate anti-selfduality equations. We construct projective moduli spaces for the torsion free sheaves and demonstrate that they are smooth. We define equivariant partition functions of these moduli spaces, finding that they coincide with the usual instanton partition functions for supersymmetric gauge theories on C^2.
Mapping QTLs Associated with Root Traits Related to Drought Resistance in Vietnamese Upland Rice

Upland rice grows on 19 million ha, about 15% of the world's rice plantation [2]. The production of upland rice is crucial to agricultural economy of many countries [15]. The yield of upland rice is very low with an average of about 1 t/ha. Drought is a major constraint to the productivity of upland rice. In this paper, we present the results on mapping QTLs for root traits related to drought resistance (maximum root length, root thickness, root weight to shoot and deep root weight to shoot ratios) in upland rice using a recombinant inbreed (RI) population derived from a cross between Vietnamese upland rice accessions. The first molecular linked of Vietnamese upland rice were constructed. The map consists of 239 markers (36 SSR and 203 AFLP markers) mapped to all 12 rice chromosomes. This map covered 3973.1 cM of rice genome with an average distance of 16.62 cM between the markers. Twenty three putative QTLs were detected. Among them, four QTLs for MRL, four QTLs for R/SR, four QTLs for DR/SR, two QTL for RN, two QTLs for RT, two for PH, and five QTLs for TN were recorded. There are several SSR markers such as RM250, RM270, RM263, RM242, RM221 linked to QTL regions. They could be very useful for drought resistant selection in rice. Some common QTLs for maximum root length and deep root weight to shoot ratio were observed in different genetic background (RDB09 × R2021 and IR64 × Azorean populations) and ecological locations (IRRI and Vietnam). These QTLs could be very useful for precise locating drought resistant gene(s) and marker-assisted selection. AJSTD Vol. 23 Issue 4 pp. 323-332 (2006)
Cytotoxicity Evaluation of Ammonia-Modified Graphene Oxide Particles in Lung Cancer Cells and Embryonic Stem Cells

Potential toxicity of graphene oxide (GO) is a subject of increasing research interest in the recent years. Here, we have evaluated the cytotoxicity of ammonia-modified GO (GO-NH2) and pristine GO particles in human lung cancer cells, A549 and embryonic stem cells, Lep3 exposed to different particles concentrations (0.1, 1, 10, 20, and 50 μg/ml) for different times (24 and 48h). Compared with GO, GO-NH2 particles possessed smaller size, positive surface charge and higher thickness. An increased propensity to aggregation in cell cultures was also found for GO-NH2 particles. Cytotoxicity evaluation revealed that GO-NH2 particles are more toxic than pristine GO. Applied at concentrations of 10, 20 and 50 μg/ml for 24h they affect significantly cell morphology of viable embryonic stem cells whereas human lung cancer A549 cells seem to be relatively more resistant to short-time exposure. After 48h exposure however cell proliferation of A549 cells was strongly suppressed in a dose-dependent manner while the proliferation ability of embryonic stem cells was not affected. These results suggested that both GO particles exert different degree of cytotoxicity which is time, dose and cell dependent. In general, ammonia-modified GO particles are more toxic than the pristine GO which should be taken into account for future biomedical applications.
Age dependent costs of reproduction in a sexually dimorphic species

Energy and time are two of the most important factors limiting the investment spent on reproduction for an organism. Due to this limitation, individuals have to balance between using energy for maintenance or growth and using it for reproduction. In many polygynous male mammals, reproduction has been pointed out to be the most energetically costly time of the year and in sexually size dimorphic species mortality is sex-biased toward the larger sex. Fallow deer is a polygynous, seasonally breeding species demonstrating a high level of sexual size dimorphism where males can be double the size of females. During the breeding season, males compete for females and display on the breeding site. Behaviours like fighting, vocalization and a reduction in forage intake can be very costly and males often loose a large amount of weight. In this study, I estimate the cost of reproduction by using culling data together with movement data collected from wild GPS-marked male fallow deer. I compare timing of body mass- and bone marrow fat loss with daily average movements and home range sizes between different age classes during time of rut. Mature males (≥ 4-years-old) lost on average 24% of their body mass during pre- and post-rut and had a decline in bone marrow fat of approx. 20%. Simultaneously, younger males (≤ 2-years-old) lost much less, if anything. Additionally, males 1 – 2-years-old had the highest mobility during rut while 4 year- and older ones moved least. There were no significant differences in home range sizes between mature and immature males and of all seasons was autumn the season with largest home range sizes, highly influenced by the time of rut. These results suggest that the loss in body mass is not due to a higher mobility during rut and the distinct decline in both body mass and bone marrow fat indicates a large investment into reproduction in mature males. Finally, as far as I know, there are no previous published studies ever of male fallow deer home range sizes, based on GPS-data, making this study unique from that perspective.
Inbreeding not stress increases fluctuating asymmetry in the bulb mite

In this study, I examined the effects of inbreeding and stress on fluctuating asymmetry and body length in the bulb mite, Rhizoglyphus robini. Mites were subjected to six generations of brother-sister mating and inbred lines were then crossed to obtain inbred and outbred progeny. At the larval stage, both the inbred and outbred progeny were divided between two treatments: the control was reared at a stable temperature of 22°C, whereas the stressed lines were kept under oscillating temperatures of between 10°C (night) and 28°C (day) until reaching adulthood. Fluctuating asymmetry, quantified by means of procrustean analysis based on five landmarks, and body length were measured for one male from each line. Fluctuating asymmetry increased with inbreeding but not with stress. In contrast, body length decreased with stress but not with inbreeding. There was no significant interaction between stress and inbreeding in their effect on either fluctuating asymmetry or body length.
X-ray versus infrared selection of distant galaxy clusters: a case study using the XMM–LSS and SpARCS cluster samples

We present a comparison of two samples of z>0.8 galaxy clusters selected using different wavelength-dependent techniques and examine the physical differences between them. We consider 18 clusters from the X-ray selected XMM-LSS distant cluster survey and 92 clusters from the optical-MIR selected SpARCS cluster survey. Both samples are selected from the same approximately 9 square degree sky area and we examine them using common XMM-Newton, Spitzer-SWIRE and CFHT Legacy Survey data. Clusters from each sample are compared employing aperture measures of X-ray and MIR emission. We divide the SpARCS distant cluster sample into three sub-samples: a) X-ray bright, b) X-ray faint, MIR bright, and c) X-ray faint, MIR faint clusters. We determine that X-ray and MIR selected clusters display very similar surface brightness distributions of galaxy MIR light. In addition, the average location and amplitude of the galaxy red sequence as measured from stacked colour histograms is very similar in the X-ray and MIR-selected samples. The sub-sample of X-ray faint, MIR bright clusters displays a distribution of BCG-barycentre position offsets which extends to higher values than all other samples. This observation indicates that such clusters may exist in a more disturbed state compared to the majority of the distant cluster population sampled by XMM-LSS and SpARCS. This conclusion is supported by stacked X-ray images for the X-ray faint, MIR bright cluster sub-sample that display weak, centrally-concentrated X-ray emission, consistent with a population of growing clusters accreting from an extended envelope of material.
Electrons in quantum dots: One by one

A quantum point contact placed close to a quantum dot can be used as a charge detector with time resolution to monitor the charge flow on the level of individual electrons. The current through the quantum point contact may take two possible values corresponding to the situation of an additional electron being on or off the quantum dot. Time traces of such two-level behavior allow to measure the average current, the tunnel rates in and out of the quantum dot, the time-dependent fluctuations of the current (noise), as well as higher-order current correlations. This high-sensitivity method to measure charge flow can also be used to detect time-resolved single-electron interference.
A Green Approach towards the Synthesis of Enantio Pure Diols Using Horse Radish Peroxidase Enzyme Immobilized on Magnetic Nanoparticles

Enantiopure epoxides and their corresponding chiral vicinal diols serve as valuable intermediates in the synthesis of biologically active pharma and agro-compounds and also value added fine chemicals. Biocatalysts are well known for their selective hydrolysis of racemic epoxides to give optically pure chiral diols. This study highlights an efficient process of synthesis of chiral vicinal diols in good yields and enantioselectiviy using horse radish peroxidase enzyme immobilized on the amine functionalized magnetic nano particles (Fe3O4 nanoparticles) as enzyme carriers. It also facilitates separation of MNP-immobilized enzymes by applying external magnetic field. The immobilization of magnetic nano particles was confirmed by transmission electron microscope (TEM) and scanning electron microscope (SEM). The MNP-immobilized peroxidase enzyme improved stability of the enzyme and has shown broader substrate specificity in enantioselective hydrolysis of racemic epoxides, under mild and environmentally friendly conditions. The methodology MNP-immobilized enzyme developed in the synthesis of chiral diols has a potential for use in large-scale applications.
Microwave thermal emission from the zodiacal dust cloud predicted with contemporary meteoroid models

Predictions of the microwave thermal emission from the interplanetary dustcloud are made using several contemporary meteoroid models to construct thedistributions of cross-section area of dust in space, and applying the Mielight-scattering theory to estimate the temperatures and emissivities of dustparticles in broad size and heliocentric distance ranges. In particular, themodel of the interplanetary dust cloud by Kelsall et al. (1998, ApJ 508:44-73), the five populations of interplanetary meteoroids of Divine (1993, JGR98(E9): 17,029-17,048) and the Interplanetary Meteoroid Engineering Model(IMEM) by Dikarev et al. (2004, EMP 95: 109-122) are used in combination withthe optical properties of olivine, carbonaceous and iron spherical particles.The Kelsall model has been widely accepted by the Cosmic Microwave Background(CMB) community. We show, however, that it predicts the microwave emission frominterplanetary dust remarkably different from the results of application of themeteoroid engineering models. We make maps and spectra of the microwaveemission predicted by the three models assuming variant composition of dustparticles. Predictions can be used to look for the emission from interplanetarydust in CMB experiments as well as to plan new observations.
Implementing IT Security Penetration Testing in Higher Education Institute

The higher educational industry has unique information security requirements as the organization holds critical data and information of students, employees, research findings as well as other university’s main agenda information. This paper proposed an enhanced process flow for web deployment process by implementing IT security penetration testing practices in University Teknologi MARA (UiTM) Pahang, Jengka Campus, as a way to early detection, reduce and prevent the institution’s information security and services. This empirical research is based on qualitative data analysis which applied action research and interviews that requires researcher to study the existing university’s IT security policy, infrastructure and available services. The development of the penetration testing process flow is guided by various industry standard penetration testing frameworks and literature review.
A FRAMEWORK FOR DECISION AND INTELLIGENCE SYSTEMS BASED ON INPUT AND OUTPUT TYPES

In tracing the evolution of computer based Management Support Systems (MSS), three main generations or classes can be distinguished. These generations, in order of their emergence, may be identified as Data Management Systems (DMS), Information Management Systems IMS), and Knowledge Management Systems (KMS). The common objective among these three classes of systems is supporting managerial decision making. One distinguishing aspect among these three classes is the type of input and output (viz. data, information, and knowledge) that these systems handle, and consequently the level and the form of support that they provide. In this paper we explore these three classes of systems from an input-output perspective. In particular, this paper offers a framework for classifying MSS based on their input and output types, with particular focus on the input side. By developing an input-output based framework for current MSS, we hope to provide a foundation to develop an agenda for the next generation of MSS.
The Effectiveness of Environmental Education: Can We Turn Tourists into 'Greenies'?

A study which tested the effectiveness of an education programme for managing tourists was conducted at Tangalooma, Australia. At this holiday resort tourists are able to hand-feed a group of wild dolphins which visit the shallow waters adjacent to the resort's beach. The education programme, which uses techniques derived from cognitive psychology and learning theory, attempted to prompt increased enjoyment, knowledge and improved environmental attitudes, intentions and behaviour in participants. The study, which compared a control group who were not exposed to the education with an experiment group who were, found that desirable changes did occur as a result of the programme. This research provides much needed evidence that education can be an effective means of managing tourists' interaction with wildlife and the natural environment © 1997 John Wiley & Sons, Ltd.
KNApSAcK gene classification system for Arabidopsis thaliana: Comparative genomic analysis of unicellular to seed plants

Proper functional classification and statistical assessment of a set of genes is very important for the purpose of comparison of gene compositions in genomes between different plant species as well as for the post-genomic research such as assessment of tissue and cell conditions concerning gene expression and metabolite accumulation profiles in transcriptomics and metabolomics. So we defined five-level categories concerning Arabidopsis thaliana genes by surveying approximately 3,000 references and classified 14,525 of 27,677 genes into different categories. Based on the classification information accumulated from various sources, we have developed a software tool called 'Arabidopsis Gene Classifier'. By using this classifier system, we performed the comparative genomic analyses of five genome sequences of the plants, Chlamydomonas reinhardtii, Physcomitrella patens, Selaginella moellendorffii, A. thaliana and Oryza sativa, and extracted statistically significant differences in their gene compositions concerning metabolic pathways.
Elastomeric Nanocomposite Based on Exfoliated Graphene Oxide and Its Characteristics without Vulcanization

Rubber nanocomposites have emerged as one of the advanced materials in recent years. The aim of this work was to homogeneously disperse graphene oxide (GO) sheets into Nitrile Butadiene Rubber (NBR) and investigate the characteristics of GO/NBR nanocomposite without vulcanization. A suitable solvent was found to dissolve dry NBR while GO was exfoliated completely in an aqueous base solution using sonication. GO was dispersed into NBR at different loadings by solution mixing to produce unvulcanized GO/NBR nanocomposites. Scanning Electron Microscopy (SEM), Fourier-Transform Infrared Spectroscopy (FTIR), and X-Ray Diffraction (XRD) were used to characterize the samples. Furthermore, mechanical and electrical properties of unvulcanized GO/NBR nanocomposites were carried out to determine the influence of GO on the NBR properties. The results showed that the modulus of GO/NBR nanocomposite at 1 wt% of GO was enhanced by about 238% compared with unfilled NBR. These results provide insight into the properties of unvulcanized GO/NBR nanocomposite for application as coatings or adhesives.
Determinants of Portuguese bank’s provisioning policies: Discretionary behaviour of generic and specific allowances

In this paper we test for the impact of the regulatory environment on a bank’s discretionary provisioning practices. We develop a model that structures the dynamics of the provision policy for the two classes of provisions: generic provisions and specific provisions. The model is tested using a comprehensive database of all financial institutions operating in Portugal for 1990-2000. This unique dataset comprises banks subject to the Portuguese rules as well as bank subsidiaries subject to their home-country regulation and we were able to identify distinct behaviours between them. Our results show the importance of handling the two types of provisions separately. They support the hypothesis that banks have a discretionary behaviour in setting up their provisions, and find evidence of income-smoothing and capital management. We also find that the regulatory regime impacts on discretionary provisioning policies because banks when forced to increase one type of provision react by reducing the discretionary component of the other, a finding we designated as a substitution effect.