Miracle-dz/UniFAR-FTUs huggingface dataset:
Breathlessness, anxiety, depression and function - the BAD-F study: a cross-sectional, population prevalence study in adults.

Introduction This study evaluated associations between chronic breathlessness and: anxiety; depression; functional status in the general population. Methods This cross sectional cohort of consenting adults (≥18 years) us ed an online survey. Quota sampling (n=3,000) was employed reflecting the 2016 national census for sex, age and place of residence. Other data included: Patient Health Questionnaire for Depression and Anxiety (PHQ-4); the modified Medical Research Council (mMRC) breathlessness scale and the Australia-modified Karnofsky Performance Scale (AKPS). Multinomial logistic regression assessed predictors. Results 2977 respondents had P revalence of was ; 6.0%; coexisting anxiety/depression 6.1% and poorer functional status (AKPS ) 1.6%. Poorest function was in the co-existing anxiety/depression group with 11.6%. The highest proportions of people with breathlessness were found in the co-existing anxiety/depression group (10.6%) and depression only (8.8%).
The Limit-in/out Approach to the Dirac Delta (with an Alternative Integral Representation)

The integral representation of the Dirac delta is the most usual way of representing this mathematical object, with which many physical disciplines, including quantum ﬁeld theory, quantum mechanics, signal processing, optics or astronomy, have been successfully formulated. Although the delta is an ill-behaved function in the conventional sense, the larger framework of distribution theory enabled rigorous use of it and put it on a par with well-behaved representations, such as the unit impulse function or the Lorentzian and Gaussian representations, by placing the limit outside of the integral sign under which the delta is deﬁned. The framework is mathematically impeccable, but requires to impose restrictive conditions on the convolving test function. We discuss these requirements and propose an alternative integral representation that is well-behaved and satisﬁes the sifting property for any continuous convolving function, if the Dirac delta is reinterpreted as the limit of a sequence of functions and the limit is positioned under the integral sign in order to exploit the fact that it takes non-null values only in a speciﬁc, arbitrarily small vicinity of the origin, as will be shown. We use the same procedure to prove the sampling property for the four representations mentioned above.
Dihydropyridine Ca 2+ Channel Blockers Increase Cytosolic [Ca 2+ ] by Activating Ca 2+ -sensing Receptors in Pulmonary Arterial Smooth Muscle Cells

2+ The dihydropyridine Ca 2+ channel blockers, previous study demonstrated that the Ca 2+ -sensing receptor (CaSR) was upregulated and the extracellular Ca 2+ -induced increase in [Ca 2+ ] cyt was enhanced in PASMC from patients with IPAH and animals with experimental pulmonary hypertension. Here, we report that the dihydropyridines (eg, nifedipine) increase [Ca 2+ ] cyt by activating CaSR in PASMC from IPAH patients (in which CaSR is upregulated), but not in normal PASMC. in 2+ ] cyt in IPAH-PASMC was concentration dependent with a half maximal effective concentration of 0.20 µ mol/L. Knockdown of CaSR with siRNA in IPAH-PASMC significantly inhibited the nifedipine-induced increase in [Ca 2+ ] cyt , whereas overexpression of CaSR in normal PASMC conferred the nifedipine-induced rise in [Ca 2+ ] cyt . Other dihydropyridines, nicardipine and Bay K8644, had similar augmenting effects on the CaSR-mediated increase in [Ca 2+ ] cyt in IPAH-PASMC; however, the nondihydropyridine blockers, such as diltiazem and verapamil, had no effect on the CaSR-mediated rise in [Ca 2+ ] cyt . Conclusions: The dihydropyridine derivatives increase [Ca 2+ ] cyt by potentiating the activity of CaSR in PASMC independently of their blocking (or activating) effect on Ca 2+ channels; therefore, it is possible that the use of dihydropyridine Ca 2+ channel blockers (eg, nifedipine) to treat IPAH patients with upregulated CaSR in PASMC may exacerbate pulmonary hypertension. ( Circ Res . 2013;4:640-650.) is upregulated IPAH-PASMC, contrib-uting to enhanced Ca signaling and PASMC
Formation of Titanium Dioxide Nanoparticles by Anodization of Valve Metals

INFO 2019 TiO 2 nanoparticles (TNPs) were successfully formed by anodization of Ti foil in aqueous (100 mL of Na 2 SO 4 ) and an organic (glycerol/H 2 O) electrolyte containing 0.7 g of NH 4 Cl at 20 V for 60 min. The morphology of the formed TNPs was discussed. It was found that TNPs and can be formed in both aqueous and organic electrolytes. The diameter of TNPs formed in organic and inorganic solution was generally in the range of 50 nm to 100 nm and the length is in the range of 300 nm to 700 nm. XRD analysis revealed an amorphous phase of the as-anodized sample regardless of the electrolytes used in this work. The thermal annealing at 700 o C indicated the sample dominated by the presence of rutile phase together with anatase phase
Board 134: Methods for Conducting a Scoping Literature Review on Engineering Graduate Student Mental Health (Work in Progress)

and Full-Text Is this study focused on U.S. populations? Yes, Not Sure Are graduate students a major focus of this study? Yes, Not Sure Are the students in an Engineering discipline/field of study? Yes, Not Sure Does the abstract discuss mental health? Yes, Not Sure Full-Text Only What mental health keyword terms are used? Any non-chronic ailment. What degree programs are the students a part of? Masters, Doctoral, Graduate What disciplines are explicitly stated? Engineering Where was this article published? Any journal publication. Conclusions and Future Work Although they have been touched on through other aspects of this project, Stage 4: Charting the Data and Stage 5: Collating, Summarizing and Reporting the Results are still in progress. The current focus is the completion of Stage 3 before critically reflecting on the screening process. This will allow for more refinement and solidarity and therefore a better-defined research scope and review process. The research team will critically reflect once more on the results from the full-text screening. This will enable a full-text coding guide to be developed so that the information collected from each eligible publication is uniform. Although some of the information that will be presented in the fulltext coding guide is evident (e.g., title, author, journal of publication, focus population), there needs to be lengthier discussions surrounding potential study designs, anticipated results, and how to best categorize and present results.
Equipamentos de Climatização Predictive Maintenance Mechanisms for Heating Equipment

Heating appliances such as HVAC systems are susceptible to failures that may result in disruption of important operations. With this in mind, it is relevant to increase the efficiency of those solutions and diminish the number of detected faults. Moreover, understand why these failures occur that be relevant for future devices. Thus, there is a need to develop methods that allow the identification of eventual failures before they occur. This is only achievable when solutions capable of analyzing data, interpret it and obtaining knowledge from it, are created. This dissertation presents an infrastructure that supports the inspection of failure detection in boilers, making viable to forecast faults and errors. A major part of the work is data analysis and the creation of procedures that can process it. The main goal is creating an efficient system able to identify, predict and notify the occurrence of failure events.
ZnO/MoS2-Based Enhanced Humidity Sensor Prototype With Android App Interface for Mobile Platform

Humidity sensors have wide range of applications. In this paper, an inorganic hybrid thin film of molybdenum disulphide (MoS<inline-formula> <tex-math notation="LaTeX">$_{\textbf {2}}$ </tex-math></inline-formula>)/zinc oxide (ZnO) was prepared as the sensing layer to develop a resistive humidity sensor containing aluminium electrodes on Si/SiO<inline-formula> <tex-math notation="LaTeX">$_{\textbf {2}}$ </tex-math></inline-formula> substrate. The composite was analyzed using scanning electron microscopy, transmission electron microscopy, X-ray photoelectron spectroscopy, and X-ray diffraction for their morphology and crystalline information. The sensor was exposed to various levels of relative humidity (RH) at room temperature and the response was found to be far better than pristine MoS<inline-formula> <tex-math notation="LaTeX">$_{\textbf {2}}$ </tex-math></inline-formula> or ZnO-based humidity sensors with the maximum response being 301 times at 85% RH. The results were reproducible with fast response and recovery, stable over a month with negligible hysteresis. A cost effective prototype was built on printed circuit board, and the data were acquired and transmitted to smartphone wirelessly using a Wi-Fi module (ESP 8266) interfaced to FRDM-KL25Z development platform. The Android application developed for the smartphone had the capability to switch ON/OFF the sensor device over Wi-Fi. Thus, our sensor device holds a great potential to develop an ultrasensitive, low power, low cost, and fast humidity sensor capable of indoor air quality monitoring in home automation systems (smart home).
Social Responsibility in Future Worlds: Using Student-Led Futures Thinking Practices to Assist in Redesigning Engineering Education

This research explores the potential for integrating futures thinking and speculative design practices in undergraduate engineering education, as a move to push Canadian engineering pedagogy into student-led spaces for more creative, reflective, and civic-oriented thinking. The research examines iterative design and development sessions, which detail the transformation of an educational, student-led intervention into an exploratory, futures-based workshop— Undiscipline. Though pilot play sessions, the potential of this tool is examined, particularly in its encouragement of participants to continually question their perception of the future, their understanding of society, and their role and responsibility to shape a preferable future. Lastly, this study discusses the potential for this game as a tool for student-led and values-driven education, to propose the implementation of futures studies in mainstream education as a method for reflective and creative growth, and how Undiscipline can be used as a lens to examine institutional pushback and burgeoning possibilities for educator implementation.
Team Assistance in a Software Engineering Team: A Field Study

— Physically collocated teammates often interact spontaneously while working solo on their assigned tasks. These ad hoc interactions could be perceived as counterproductive when they are seen as interruptions or they could be perceived as productive when they are seen as ad hoc team assistances, which contribute to the team awareness, trust amongst team members, and improved shared mental model. This paper reports on a field study performed in a professional environment. Team activities have been continuously video recorded over a period of two months. More than 400 ad hoc interactions have been analyzed. Ad hoc interactions required up to 30% of the team total time. These ad hoc interactions involve all the team members and as such may contribute to team awareness and improvement of shared mental model. Ad hoc team assistances can be categorized according to two purposes: the application domain or the development environment. This study shed light on the team dynamics of collocated teams and can provide insight into the challenges faced by the distributed software development teams. Suggestions are formulated for the management of team assistance activities.
alpha- and beta-Adducin polymorphisms affect podocyte proteins and proteinuria in rodents and decline of renal function in human IgA nephropathy.

Adducins are cytoskeletal actin-binding proteins ( α , β , γ ) that function as heterodimers and heterotetramers and are encoded by distinct genes. Experimental and clinical evidence implicates α - and β -adducin variants in hypertension and renal dysfunction. Here, we have addressed the role of α - and β -adducin on glomerular function and disease using β -adducin null mice, congenic substrains for α - and β -adducin from the Milan hyperten-Mara this study. sive (MHS) and Milan normotensive (MNS) rats and patients with IgA nephropathy. Targeted deletion of β adducin in mice reduced urinary protein excretion, preceded by an increase of podocyte protein expression (phospho-nephrin, synaptopodin, α -actinin, ZO-1, Fyn). The introgression of polymorphic MHS β -adducin locus into MNS ( Add2 , 529R) rats was associated with an early reduction of podocyte protein expression (nephrin, synaptopodin, α -actinin, ZO-1, podocin, Fyn), followed by severe glomerular and interstitial lesions and increased urinary protein excretion. These alterations were markedly attenuated when the polymorphic MHS α -adducin locus was also present ( Add1 , 316Y). In patients with IgA nephropathy, the rate of decline of renal function over time was associated to polymorphic β -adducin (ADD2, 1797T, rs4984 ) with a significant interaction with α -adducin (ADD1, 460W, rs4961 ). These findings suggest that adducin genetic variants participate in the development of glomerular lesions by modulating the expression of specific podocyte proteins.
Essential Factors for Usability and Acceptance of Mobile Learning in Ugandan Primary Schools

Two di erent focus groups in primary schools in Uganda participated in this study to investigate critical aspects of usability comparing two di erent educational mobile applications. The first group was already familiar with both applications, while the second group had no previous experiences of the applications. Furthermore, interviews were performed with a head teacher as well as two CEOs and founders of two start ups developing educational mobile applications for children, in order to investigate challenges with implementation of mobile learning in schools in Uganda. The results showed that one of the applications was not fully compatible with the devices used by the target group and that swiping was perceived less natural than clicking. Regarding organizational factors of implementation in schools, financial limitations and insu cient computer literacy among employees were revealed as critical obstacles. Moreover, improvements of the method used during the user tests with children in foreign contexts are discussed. Sammanfattning—I denna studie deltog två fokusgrupper med barn från två olika grundskolor i Uganda för att undersöka kritiska aspekter gällande användarvänlighet genom att jämföra två mobilapplikationer som används i utbildningssammanhang. Den första gruppen var redan bekant med båda applikationerna, medan den andra gruppen var obekant med applikationerna. Vidare undersöktes utmaningar med implementation av mobile learning i grundskolor i Uganda genom intervjuer med en rektor från en ugandiansk grundskola samt två VDs tillika grundare från två ugandianska edTech-start-ups. Resultaten visade att en av applikationerna inte var fullständigt kompatibel med de enheter som användes av målgruppen i Uganda samt att "swipea" uppfattades mindre naturligt än att klicka. Gällande organisatoriska faktorer av implementering i skolorna visades finansiella begränsningar och anställdas otillräckliga datakunskap vara kritiska hinder. Utöver resultaten som ämnar svara på de definierade frågeställningarna diskuteras förbättringar av metoden som användes för användartesterna, i syfte att ge riktlinjer till framtida projekt i liknande sammanhang.
A literature review on performance measures of logistics management: an intellectual capital perspective

Today, logistics management requires a comprehensive set of performance indicators that measure both tangible assets and intellectual capital (IC) of organisations. Nevertheless, most of the measures used in the past mainly related to the financial aspect, although some specific components of IC, such as process efficiency and effectiveness, have been considered. Logistics literature lacks a comprehensive consideration of the diverse IC measures, and it is unclear which area of IC requires more focus and development. Therefore, to explore and identify an opportunity for improvement, this study reviews the academic literature related to IC measures in logistics management. This literature review considers 111 academic articles published between 1994 and 2016. Following the six dimensions of the IC-Index, all indicators obtained from the literature are classified according to IC elements. The key contribution of this review is that it addresses the following gaps in the literature: the limited adoption of comprehensive IC methods in logistics studies; underdevelopment of specific indicators and measures used; failure to consider all human capital as well as renewal and development elements; and, finally, lack of academic research considering the influences among the different IC elements and logistics and financial performance.
Sonographic Versuss Clinical Fetal Weight Estimation Accuracy

Background: Sonographic fetal weight estimation is an important component of antenatal care. It was found to be more reliable method to establish fetal weight at term and more consistent in various period of gestations. Aim of Study: To compare clinical and Sonographic methods for assessment of fetal weight regarding sensitivity, specificity and accuracy. Subjects and Methods: The study recruited 100 women scheduled for delivery from ante-natal care clinic with 38 weeks or more of gestation. Fetal weight was assed clinically and by ultrasound. Both techniques were compared and analyzed. Results: Ultrasound assessment of fetal weight showed better performance than the clinical method regarding absolute errors and error percentages. Ultrasound assessment showed better sensitivity and specificity in detecting fetal weight > 3500 gm. Moreover, it showed less bias on Bland–Altman plot analysis. Conclusion: Ultrasound assessment of fetal weight is safe, reliable and sensitive method of fetal weight estimation. of gestation, abnormal amniotic index, obesity and congenital malformations. Participants included in following study were subjected to careful history taking, full clinical and obstetrical examination. Clinical assessment of fetal weight was achieved by single practitioner (senior resident), by measuring length from midpoint of upper edge of symphonies pupis to the highest fundal point to give Fundal Height [FH] in centimeter then measuring Abdominal Girth [AG]
Shh in pituitary gland development

The pituitary gland originates through the interaction of two different ectodermal tissues, the neural and oral ectoderm. The neural ectoderm gives rise to the posterior pituitary, whereas part of the oral ectoderm will develop into the anterior and intermediate pituitary gland containing at least six distinct cell phenotypes (Treier and Rosenfeld, 1996; Sheng and Westphal, 1999; Burrows et al., 1999; Dasen and Rosenfeld, 1999). Recent work has begun to unravel general mechanisms of pituitary organ induction based on defining the obligatory interactions between the neural and oral ectoderm as a prerequisite for pituitary gland formation. A dual induction from the diencephalon is required for formation of Rathke’s pouch, the primordium of the pituitary gland (Ericson et al., 1998; Takuma et al., 1998; Treier et al., 1998). Both a BMP4 signal and FGF activity from the ventral diencephalon are required for the development of a definitive pouch. Two LIM homeobox factors Lhx3/Lhx4have been shown to be the earliest molecular pituitary markers expressed within the oral ectoderm and required for formation of a definitive pouch (Sheng et al., 1997). Subsequently a ventrodorsal BMP2 gradient, appearing at a Shh boundary (Treier et al., 1998), together with an opposing dorsoventral FGF8 gradient serve to determine ventral/intermediate cell phenotypes (gonadotropes, thyrotropes, somatotropes, lactotropes) and dorsal cell phenotypes (melanotropes and corticotropes), respectively, with attenuation of the BMP2 signal ultimately required for terminal differentiation. A consequence of these signaling gradients is apparently to establish overlapping expression patterns of several transcription factors in Rathke’s pouch, allowing positional determination of pituitary cell types by E10.5-E12.5. Several f ctors exhibit spatially restricted domains of expression, including Isl1 (Ericson et al., 1998; Treier et al., 1998), P-Frk (Treier et al., 1998), Brn4 (Sornson et al., 1996; also known as Pou3F4), and Gata2(Dasen et al., 1999). In the final stages, the pituitary cell types express a series of differentiation markers which appear in distinct temporal and spatial patterns between E14.5-E16.5, including corticotropes, secreting adrenocorticotropin hormone (ACTH); melanotropes, secreting melanocyte-stimulating hormone (MSH); thyrotropes, secreting thyroid-stimulating hormone (TSH); gonadotropes, secreting luteinizing hormone (LH) and follicle-stimulating hormone 377 Development 128, 377-386 (2001) Printed in Great Britain © The Company of Biologists Limited 2001 DEV5414
-24-network effects and in traditional MTP/SCS

Cohort Model The cohort model draws on a modeling exercise SACOG conducted for the California Air Resources Board (CARB) to stress-test their plan’s projected reduction of greenhouse gas (GHG) emissions for the year 2036 under the requirements of California Senate Bill 375 (Steinberg, 2008). To generate SB 375 emissions results for the exercise, SACOG used the 2016 version of SACSIM (Bradley, Bowman, & Griesenbeck, 2010) also known as SACSIM 16, a regional activity-based travel model that informs development and evaluates performance of the MTP/SCS.
GSPB theory for GCHS and QCPB theory for QCHS

In this note, we comprehensively sort out the theoretical system between the generalized structural Poisson bracket (GSPB) theory for the generalized covariant Hamilton system (GCHS) and the quantum covariant Poisson bracket (QCPB) theory for quantum covariant Hamiltonian system (QCHS).
The Rise and Fall of Knapsack Cryptosystems

Cryptosystems based on the knapsack problem were among the first public key systems to be invented and for a while were considered to be among the most promising. However, essentially all of the knapsack cryptosystems that have been proposed so far have been broken. These notes outline the basic constructions of these cryptosystems and attacks that have been developed on them.
ATS Core Curriculum 2020. Pediatric Pulmonary Medicine

The American Thoracic Society Core Curriculum updates clinicians annually in adult and pediatric pulmonary disease, medical critical care, and sleep medicine, in a 3- to 4-year recurring cycle of topics. These topics will be presented at the 2020 International Conference. Below is the pediatric pulmonary medicine core, including pediatric hypoxemic respiratory failure; modalities in noninvasive management of chronic respiratory failure in childhood; surgical and nonsurgical management of congenital lung malformations; an update on smoke inhalation lung injury; an update on vaporizers, e-cigarettes, and other electronic delivery systems; pulmonary complications of sarcoidosis; pulmonary complications of congenital heart disease; and updates on the management of congenital diaphragmatic hernia.