Miracle-dz/UniFAR-FTUs huggingface dataset:
maging the Effects of Methylphenidate on Brain opamine: New Model on Its Therapeutic Actions for ttention-Deficit/Hyperactivity Disorder

ethylphenidate hydrochloride (MP) is an effective treatment for attention-deficit/hyperactivity disorder (ADHD), a common eurobehavioral disorder of childhood onset characterized by inattention, hyperactivity, and distractibility. Methylphenidate ydrochloride blocks the dopamine transporters (DAT), the main mechanism for removing dopamine (DA) from the synapse, is elieved to be involved in its therapeutic properties. However, the mechanism(s) by which increases in DA improve symptomatology in DHD are not completely understood. Our studies of the dopaminergic effects of MP in the human brain using positron emission omography (PET) have shown that MP blocks DAT, and that extracellular DA increases in proportion to the level of blockade and the ate of DA release (modulated by DA cell firing). These DA increases are greater when MP is given concomitantly with a salient timulus than with a neutral stimulus, documenting the context dependency of MP effects. Additionally, MP-induced increases in DA re associated with an enhanced perception of the stimulus as salient. We postulate the MP’s therapeutic effects are due in part to its bility to enhance the magnitude of DA increases induced by stimuli that by themselves generate weak responses, enhancing their aliency and the attention and interest they elicit. We postulate that these effects would improve school performance.
In Vitro Antioxidant Activity and Polyphenolic Contents of Rauvolfia tetraphylla L . , Rhinacanthus nasutus Kurz . and Solena amplexicaulis ( Lam . )

Methanol extracts of the leaves of Rauvolfia tetraphylla L. , Rhinacanthus nasutus Kurz. and Solena amplexicaulis (Lam.) were evaluated for their antioxidant activity. The extracts were investigated for total phenolic and flavonoid contents, antihemolytic activity, reducing power capacity and radical scavenging activity towards DPPH and ABTS radicals. The total phenol content was in the range of 25-41.7 mg gallic acid equivalent/g dry weight (DW) of sample and the total flavonoid content varied from 10.2-25.8 mg quercetin equivalent/g of DW sample. The antioxidant activity was expressed as IC50 values. The IC50 values of DPPH activity for R. tetraphylla, R. nasutus and S. amplexicaulis extracts were 170, 230 and 190 μg extract/ml, respectively. The IC50 values of ABTS scavenging (80-120 μg extract/ml) and antihemolytic activity (135-157 μg extract/ml) were calculated. The IC50 value of reducing power activity for R. tetraphylla extract was 200 μg extract/ml while R. nasutus and S. amplexicaulis extracts at a concentration of 250 μg/ml did not reach 50% of reducing capacity. In the present study, linear regression analysis of antihemolytic, DPPH and reducing power activities with total phenol and flavonoid contents were evaluated and showed a positive correlation (R > 0.735). However, no correlation was found between ABTS activity and polyphenol content. The results confirm that polyphenols in methanol extracts of plants are largely responsible for their antioxidant activities. _____________________________________________________________________________________________________________
A Classification Method for Silhouettes of Various Clothes

In this paper, we propose an effective classification method for the silhouettes of various kinds of clothes. There are two approaches to analyzing clothes. The first method focuses on the basic elements of a garment’s design, from the viewpoint of its creator. The second method features detailed categories with respect to the garment made. The silhouette of a garment is one of the most important pieces of information in fashion design trends. Here, we focused on classifying silhouettes that lead to the creation of trends, rather than classifying items made of clothing. This classification makes it possible to create a data set of silhouettes that can be used to multi-class classifications in a deep neural network.
A Survey on Sentiment Analysis on Twitter Data Using Different Techniques

Sentiment analysis is a broad research area in academic as well as business field. The term sentiment refers to the feelings or opinion of the person towards some particular domain. Hence it is also known as opinion mining. It leads to the subjective impressions towards the domain, not facts. It can be expressed in terms of polarity, reviews or previously by thumbs up and down to denote positive and negative sentiments respectively. Sentiments can be analyzed using NLP, statistics or machine learning techniques. Sentiment analysis may ask questions regarding “customer satisfaction and dissatisfaction, “public opinion towards new iPhone series launched” etc. In real world, public or consumer opinions about some product or brand are very important for its sell. Hence sentiment analysis is a very important research area for real life applications i.e. decision making. One of the most visited social networking sites by millions of users is twitter where they share their opinion about various domains like politics, brands, products, celebrities etc.Many research works are carried out in the field of sentiment analysis. But they are only useful in modeling and tracking public sentiments. They had not found exact reasons behind the sentiment variations and hence not useful in decision making. Sentiment analysis has many applications in various domains like political domain, sociology and real time event detection like earthquakes. Previously research was carried out to model and track public sentiments. But with the advancement in research, today we can use it for interpreting the reasons of the sentiment change in public opinion, mining and summarizing products reviews, to solve the polarity shift problem by performing dual sentiment analysis. Here we use different algorithms/models to perform the above tasks like LDA approach, DSA model, Naïve Bayes (NB) classifier, Support Vector Machine (SVM) algorithm and so on. Keywords— Opinion mining, Latent Dirichlet Allocation, sentiment analysis, emerging topic mining, event summarization, foreground topics.
FEASIBILITY STUDY OF ACID DYE REMOVAL FROM SYNTHETIC AQUEOUS SOLUTIONS BY SORPTION USING TWO VARIETIES OF ORANGE PEEL IN BATCH MODE

The ability of two varieties of orange peels namely: tomson navel and clementine, as an inexpensive sorbent for the removal of two acid dyes: bemacid blue and bemacid yellow from synthetic aqueous solutions has been studied. The dyes sorption kinetics and equilibrium isotherms have been investigated at acid initial solution pH (2.20) in batch conditions. The effects of some parameters such as: contact time, initial dye concentration and dye type on the kinetics of dye sorption, have been studied. For each system dye-sorbent, the quantity of dye sorbed at equilibrium depends on contact time, initial dye concentration and increases with an increase of these two parameters. The sorption process of each dye by the two varieties of orange peel followed a pseudo second – order rate kinetics. The Langmuir model was found to provide a good fit to the experimental data of dye sorption equilibrium than the Freundlich model for both dyes. Under the experimental conditions tested here, acceptable maximum dye sorption capacities were obtained: about 32.34 and 31.39 mg/g, respectively, for bemacid yellow and bemacid blue using the clementine variety, and, 30.71 and 29.59 mg/g, respectively, for bemacid blue and bemacid yellow using the tomson navel variety under the experimental conditions tested here.
Complete Genomes of Bacillus coagulans S-lac and Bacillus subtilis TO-A JPC, Two Phylogenetically Distinct Probiotics

Several spore-forming strains of Bacillus are marketed as probiotics due to their ability to survive harsh gastrointestinal conditions and confer health benefits to the host. We report the complete genomes of two commercially available probiotics, Bacillus coagulans S-lac and Bacillus subtilis TO-A JPC, and compare them with the genomes of other Bacillus and Lactobacillus. The taxonomic position of both organisms was established with a maximum-likelihood tree based on twenty six housekeeping proteins. Analysis of all probiotic strains of Bacillus and Lactobacillus reveal that the essential sporulation proteins are conserved in all Bacillus probiotic strains while they are absent in Lactobacillus spp. We identified various antibiotic resistance, stress-related, and adhesion-related domains in these organisms, which likely provide support in exerting probiotic action by enabling adhesion to host epithelial cells and survival during antibiotic treatment and harsh conditions.
Cerberus : A Multiheaded Derenderer

To generalize to novel visual scenes with new viewpoints and new object poses, a visual system needs representations of the shapes of the parts of an object that are invariant to changes in viewpoint or pose. 3D graphics representations disentangle visual factors such as viewpoints and lighting from object structure in a natural way. It is possible to learn to invert the process that converts 3D graphics representations into 2D images, provided the 3D graphics representations are available as labels. When only the unlabeled images are available, however, learning to derender is much harder. We consider a simple model which is just a set of free floating parts. Each part has its own relation to the camera and its own triangular mesh which can be deformed to model the shape of the part. At test time, a neural network looks at a single image and extracts the shapes of the parts and their relations to the camera. Each part can be viewed as one head of a multi-headed derenderer. During training, the extracted parts are used as input to a differentiable 3D renderer and the reconstruction error is backpropagated to train the neural net. We make the learning task easier by encouraging the deformations of the part meshes to be invariant to changes in viewpoint and invariant to the changes in the relative positions of the parts that occur when the pose of an articulated body changes. Cerberus, our multi-headed derenderer, outperforms previous methods for extracting 3D parts from single images without part annotations, and it does quite well at extracting natural parts of human figures.
Novel Shuttling Domain in a Regulator (RSC1A1) of Transporter SGLT1 Steers Cell Cycle‐Dependent Nuclear Location

The gene product of RSC1A1, RS1, participates in the regulation of the Na+‐d‐glucose cotransporter SGLT1. RS1 inhibits release of SGLT1 from the trans Golgi network. In subconfluent LLC‐PK1 cells, RS1 migrates into the nucleus and modulates transcription of SGLT1, whereas most confluent cells do not contain RS1 in the nuclei. We showed that confluence‐dependent nuclear location of RS1 is because of different phases of the cell cycle and identified a RS1 nuclear shuttling domain (RNS) with an associated protein kinase C (PKC) phosphorylation site (RNS‐PKC) that mediates cell cycle‐dependent nuclear location. RNS‐PKC contains a novel non‐conventional nuclear localization signal interacting with importin β1, a nuclear export signal mediating export via protein CRM1 and a Ca2+‐dependent calmodulin binding site. PKC and calmodulin compete for binding to RNS‐PKC. Mutagenesis experiments and analyses of the phosphorylation status suggest the following sequences of events. Subconfluent cells without and with synchronization to the G2/M phase contain non‐phosphorylated RNS‐PKC that mediates nuclear import of RS1 but not its export. During confluence or synchronization of subconfluent cells to the G2/M phase, phosphorylation of RNS‐PKC mediates rapid nuclear export of RS1.
Canonical Values vs. the Law of Large Numbers: The Canadian Literary Canon in the Age of Big Data

In this article, I propose an alternative technique to the traditional method of constitution of the literary canon. Instead of basing the determination of the canon on different values, I scrutinize the Modern Language Association International Bibliography database in order to determine the most cited authors and literary works. Specifically, I study Canadian literature. Thus, through the process of data mining, I obtain a sample of over 25,000 references that allows us to observe the chronological evolution and the linguistic distribution of the critical bibliography about Canadian literature. This quantitative technique yields a corpus of 151 titles and 295 writers that are cited more than 10 times in the database. Consequently, this bibliography is not the result of subjective selection criteria, but is based on the law of large numbers. Furthermore, this study shows that the quantitative analysis of bibliographic databases is an effective way to bring new light to the field of literary studies. [
Network-coding-based hybrid-ARQ for bi-directional regenerative relaying

Network coding is a promising technique to improve the throughput performance of wireless networks. In this paper, we propose a novel network-coding-based hybrid retransmission request protocol for two-way relaying system. The proposed protocol can retransmit more information in a given time interval by introducing network coding in the retransmission process, thus improving the throughput. Furthermore, we derive the frame error rate and delay performance using the L-ary pulse amplitude modulation by solving Markov state transition equations. Applying these results, the closed-form approximate solution of the throughput is acquired. Numerical results have validated our analytical results, and demonstrated that the proposed protocol outperforms the traditional hybrid retransmission request protocol for two-way relaying system by a throughput gain of about 9% when the relay lies close to the midpoint of the two users.
Identi fi cation of a commercial emmer ( Triticum dicoccum Schübl . ) by a proteomic approach

Traceability, which is the ability to trace the history, application or location of an entity, by means of recorded identifi cations, is becoming the more and more important for the certifi cation of food products. We have adopted a proteomic approach to trace three commercial varieties of emmer. We have analysed the protein pattern using two-dimensional electrophoresis. We have moreover compared amylolitic isoforms of the three emmer varieties. Our results have showed that each variety has some specifi c spots, which could be used as a molecular marker. We have also observed differences in the amylolitic activity between the three varieties of emmer.
Mutant KB cells with decreased EGF receptor expression: Biochemical characterization

Mutants of the human KB carcinoma cell line resistant to a cytotoxic conjugate of epidermal growth factor and Pseudomonas exotoxin (EGF‐PE) express a pleiotropic phenotype, which includes reduced levels of 125I‐EGF binding, without altered affinity for EGF (Lyall et al., 1987). Here, the EGF‐toxin (ET) resistant mutants were further characterized with respect to the amount and size of the EGF receptor and the level of EGF receptor RNA. These data indicate that decreased binding of 125I‐EGF in the mutants is due to reduced amounts of EGF receptor, which is associated with decreased mRNA levels. Changes in other proteins in the ET mutants were also examined. Five of the six ET mutants had a decrease in a 78,000 Mr− membrane glycoprotein. In addition, an increase in a protein with a Mr− of 40,000 and a pl = 8.0 was found in all the mutants, and an increase in a series of proteins with a Mr− of 36,000 and a pl of 6.3–6.5 was found in some of the mutants. These results confirm the pleiotropic nature of the EGF‐PE resistant mutants and show that reduced EGF binding is due to altered expression of the EGF receptor gene in the mutants.
Is there proofreading during polypeptide synthesis?

The stoichiometric efficiency with which ternary complexes containing Phe‐tRNAphe and Leu‐tRNAleu support polypeptide synthesis has been compared in a poly(U)‐directed, steady‐state translation system. When unfractionated tRNA is used to support synthesis, the number of discharged ternary complexes per peptide bond formed is an average of 48 times greater for leucine than for phenylalanine. When three purified leucine isoacceptor species are tested, they each show a characteristic ratio of ternary complexes discharged per missense insertion, normalized to that for phenylalanine: these are 103, 76, and 45 for Leu‐ tRNA2leu, Leu‐ tRNA3leu, and Leu‐ tRNA4leu, respectively. The data are consistent with the functioning of a proofreading mechanism during translation.
2017_ Proceedings.indb

Current developments in design-to-production workflows aim to allow architects to quickly prototype designs that result from advanced design processes while also embedding the constraints imposed by selected fabrication equipment. However, the enduring physical separation between design space and fabrication space, together with a continuous approach to both design, via NURBs modeling software, and fabrication, through irreversible material processing methods, limit the possibilities to extend the advantages of a “digital” approach (Ward 2010), such as full editability and reversibility, to physical realizations. In response to such issues, this paper proposes a processto allow the concurrent design and fabrication of discrete structures in a collaborative process between human designer and a 6-axis robotic arm. This requires the development of design and materialization procedures for discrete aggregations, including the modeling of assembly constraints, as well as the establishment of a communication platform between human and machine actors. This intends to offer methods to increase the accessibility of discrete design methodologies, as well as to hint at possibilities for overcoming the division between design and manufacturing (Carpo 2011; Bard et al. 2014), thus allowing intuitive design decisions to be integrated directly within assembly processes (Johns 2014).
A comparative Study on the Antioxidant Activity of TBHQ and Extracts from Rosemary and Oregano on Oxidative Stability of Palm Olein during Deep Fat Frying of Beef

Nowadays, there is a tendency toward using of natural antioxidants to avoid toxic effects of synthetic antioxidants. This study was aimed to investigate the effect of antioxidants addition in protection of palm olein as frying media during the deep fat frying of beef meatballs, since antioxidants were added to palm olein (frying media) separately as follows 200 ppm tertiary butyl hydroquinone (TBHQ), 2500 ppm rosemary extract (ROS) and 2500 ppm oregano extract (OREG) beside control treatment (antioxidants free palm olein). The results showed that the addition of antioxidants to palm olein reduce the increment in refractive index during frying process as compared to control, while ROS was have the lowest refractive index among the natural antioxidant containing treatments. In regard to relative viscosity the addition of antioxidants to palm olein results in lower relative viscosity values as compared to control treatment. Since, ROS was exhibited superior ability in reducing the formation of free fatty acids which increased during the frying process in all treatments with low rates for antioxidant containing treatments. In regard to peroxide value, TBHQ and ROS has been kept peroxide value under the ESS limit for long period of deep fat frying (150 min.) followed by OREG containing treatment (90 min.), while control sample still only 60 min under the Codex Stand (No. 210/1999) and ESS (1706/2005) peroxide limit. Changes in TBA values were increased as frying process progressed, but TBA value increasing rate was low in antioxidant containing treatments as compared to control, also TBHQ and ROS showed lower TBA values than that of OREG treatment along the frying period. Polymerization of oil increased with increasing frying time, the results showed that the addition of antioxidants to palm olein reduce the polymer compounds formation during the frying process as compared to control, but the low polymerization percent was observed for TBHQ and ROS treatments. The iodine values of frying oil were decreased as the frying time increased, but TBHQ and ROS treatments exhibited high iodine value than other treatments. Finally ROS was exhibit superior ability in protection the oil from oxidation during frying process which suggests that ROS may be a good natural antioxidant alternative to TBHQ.
On ϕ-Ricci Recurrent Almost Kenmotsu Manifolds with Nullity Distributions

The purpose of this paper is to investigate φ-Ricci recurrent and φ-Ricci symmetric almost Kenmotsu manifolds with its characteristic vector field ξ belonging to some nullity distributions. Also we obtain several corollaries. Finally, we give an example of a 5-dimensional almost Kenmotsu manifold such that ξ belongs to the (k, μ)′-nullity distribution and h′ 6= 0.
The demographic profile of Gauteng rock climbers

Within the broader tourism industry, rock climbing is becoming a popular adventure tourism activity worldwide. However, to date, rock climbing research has received relatively little attention in academic literature as the focus of studies in this field tends to be on the demand, as well as financial contribution and economic impact of rock climbers in general with little emphasis on the demographics of rock climbers. Therefore, this study proposes the demographic profile of Gauteng rock climbers. A self-completing, e-questionnaire for rock climbers (N=228) examined the demographic profile in the target marketing model. The results of this study could assist adventure tourism companies, and specifically rock climbing companies in identifying the financial contribution and economic impact that rock climbers might have on a specific local community, region or destination. Moreover, this study could assist companies in managing and marketing products and services that will meet the specific needs and wants of their identified target market. Companies should implement the last two steps of the target marketing model to proceed and successfully complete the systematic process.
Community-Search Algorithm Based on Tree Decomposition of Graphs

In this report, we discuss algorithms for community search (also called community detection), based on tree decomposition. In the tree decomposition of a graph, each tree node is labeled with a set of graph vertices, and each clique in the graph is always contained by a tree node. Also, tree nodes containing an identical graph vertex are always connected. Using such properties, we discuss an algorithm that finds a community that contains a given query node set. In addition, we calculate linkScore of each vertex in every tree node after tree decomposition. Use linkScore as boundary conditions to improve the accuracy of community-search algorithm. By pre-computing tree decomposition, the task of finding communities can be reduced. We show experimental results on community detection over real data sets.
Real-time detection of faecally contaminated drinking water with tryptophan-like fl uorescence : de fi ning threshold values

• Urgent need to screen drinking water for faecal contamination rapidly. • Multi-country assessment of TLF as an indicator of faecal contamination. • A 1.3 ppb dissolved tryptophan threshold is effective to infer contamination. • TLF is strongly correlated with thermotolerant coliform concentration. • TLF is a commercially available, easy-touse, reagentless, real-time option. ⁎ Corresponding author. E-mail address: jare1@bgs.ac. uk (J.P.R. Sorensen). https://doi.org/10.1016/j.scitotenv. 2017.11. 162 0048-9697/© 2017 Published by Elsevier B.V. a b s t r a c t a r t i c l e i n f o