Miracle-dz/UniFAR-FTUs huggingface dataset:
Multi-Modal Deep Learning for Assessing Surgeon Technical Skill

This paper introduces a new dataset of a surgical knot-tying task, and a multi-modal deep learning model that achieves comparable performance to expert human raters on this skill assessment task. Seventy-two surgical trainees and faculty were recruited for the knot-tying task, and were recorded using video, kinematic, and image data. Three expert human raters conducted the skills assessment using the Objective Structured Assessment of Technical Skill (OSATS) Global Rating Scale (GRS). We also designed and developed three deep learning models: a ResNet-based image model, a ResNet-LSTM kinematic model, and a multi-modal model leveraging the image and time-series kinematic data. All three models demonstrate performance comparable to the expert human raters on most GRS domains. The multi-modal model demonstrates the best overall performance, as measured using the mean squared error (MSE) and intraclass correlation coefficient (ICC). This work is significant since it demonstrates that multi-modal deep learning has the potential to replicate human raters on a challenging human-performed knot-tying task. The study demonstrates an algorithm with state-of-the-art performance in surgical skill assessment. As objective assessment of technical skill continues to be a growing, but resource-heavy, element of surgical education, this study is an important step towards automated surgical skill assessment, ultimately leading to reduced burden on training faculty and institutes.
On how leakage can affect the star formation rate estimation using Hα luminosity

We present observational evidence that leakage of ionizing photons from star-forming regions can affect the quantification of the star formation rate (SFR) in galaxies. This effect could partially explain the differences between the SFR estimates using the far-ultraviolet (FUV) and the Hα emission. We find that leakage could decrease the SFR(Hα)/SFR(FUV) ratio by up to 25 per cent. The evidence is based on the observation that the SFR(Hα)/SFR(FUV) ratio is lower for objects showing a shell Hα structure than for regions exhibiting a much more compact morphology. The study has been performed on three object samples: low-luminosity dwarf galaxies from the Local Volume Legacy survey, star-forming regions in the Large Magellanic Cloud and the nearby Local Group galaxy M33. For the three samples we find differences (1.1σ–1.4σ) between the SFR(Hα)/SFR(FUV) for compact and shell objects. Although leakage cannot entirely explain the observed trend of SFR(Hα)/SFR(FUV) ratios for systems with low SFR, we show that the mechanism can lead to different SFR estimates when using Hα and FUV luminosities. Therefore, further study is needed to constrain the contribution of leakage to the low SFR(Hα)/SFR(FUV) ratios observed in dwarf galaxies and its impact on the Hα flux as an SFR indicator in such objects.
Bioactive Compounds, Nutritional Quality and Antioxidant Capacity of the Red-Fleshed Kirkwood Navel and Ruby Valencia Oranges

Kirkwood Navel and Ruby Valencia are two spontaneous bud-mutations of the ordinary Washington Navel and Valencia late oranges characterized by the red coloration of their flesh. The purpose of this study was to analyze the physiological features, internal fruit quality, contents of relevant bioactive compounds and antioxidant capacity in the pulps of the red-fleshed fruits compared with the ordinary oranges during late development and maturation. In general, the content of sugars, organic acids, vitamin C, tocopherols, total phenolics and flavonoids, the hydrophilic antioxidant capacity and their changes during maturation were similar in the red-fleshed oranges and in the corresponding blond oranges. However, the mature Ruby fruits contained lower concentrations of sugars, malic and succinic acid and higher levels of citric acid than the ordinary Valencia. The major difference between the pulps of the Kirkwood and Ruby oranges and those of the ordinary oranges was the higher lipophilic antioxidant capacity and SOAC (singlet oxygen absorption capacity) of the former. Together, the high and unique content and composition of carotenoids in Kirkwood and Ruby may contribute to an enhanced antioxidant capacity without any detrimental effects on other fruit-quality attributes, making these varieties good sources of phytochemicals for the fresh-fruit and juice-processing citrus industries.
Iron emission line from the spiral galaxy M 101

Archival Suzaku data of the face-on spiral galaxy M101 were analyzed. An intense emission line at 6.72^{+0.10}_{-0.12} keV was detected in the central region. This line is identified with a K-line from He-like iron, which indicates the existence of a thin thermal plasma with a temperature of several keV. The iron line luminosity within the central 5 arcmin radius region is estimated to be (2-12)x10^{37} erg s^{-1}. The origin of the iron emission line is discussed.
Morphology of graphene thin film growth on SiC(0001)

Epitaxial films of graphene on SiC(0001) are interesting from a basic physics as well as an applications-oriented point of view. Here, we study the emerging morphology of in vacuo prepared graphene films using low-energy electron microscopy (LEEM) and angle-resolved photoemission spectroscopy (ARPES). We obtain an identification of single-layer and bilayer graphene films by comparing the characteristic features in electron reflectivity spectra in LEEM to the π-band structure as revealed by ARPES. We demonstrate that LEEM serves as a tool to accurately determine the local extent of graphene layers as well as the layer thickness.
Localization by bichromatic potentials versus Anderson localization

The one-dimensional propagation of waves in a bichromatic potential may be modeled by the Aubry-Andre Hamiltonian. This, in turn, presents a localization transition that has been observed in recent experiments using ultracold atoms or light. It is shown here that, in contrast to the Anderson model, the localization mechanism has a classical origin, namely it is not due to a quantum suppression of a classically allowed transport process, but rather is produced by a trapping by the potential. Explicit comparisons with the Anderson model as well as with experiments are presented.
High-Density Linkage Mapping of Agronomic Trait QTLs in Wheat under Water Deficit Condition using Genotyping by Sequencing (GBS)

Improvement of grain yield is the ultimate goal for wheat breeding under water-limited environments. In the present study, a high-density linkage map was developed by using genotyping-by-sequencing (GBS) of a recombinant inbred line (RIL) population derived from the cross between Iranian landrace #49 and cultivar Yecora Rojo. The population was evaluated in three locations in Iran during two years under irrigated and water deficit conditions for the agronomic traits grain yield (GY), plant height (PH), spike number per square meter (SM), 1000 kernel weight (TKW), grain number per spike (GNS), spike length (SL), biomass (BIO) and harvest index (HI). A linkage map was constructed using 5831 SNPs assigned to 21 chromosomes, spanning 3642.14 cM of the hexaploid wheat genome with an average marker density of 0.62 (markers/cM). In total, 85 QTLs were identified on 19 chromosomes (all except 5D and 6D) explaining 6.06–19.25% of the traits phenotypic variance. We could identify 20 novel QTLs explaining 8.87–19.18% of phenotypic variance on chromosomes 1A, 1B, 1D, 2B, 3A, 3B, 6A, 6B and 7A. For 35 out of 85 mapped QTLs functionally annotated genes were identified which could be related to a potential role in drought stress.
The ESO UVES advanced data products quasar sample - I. Dataset and new NH I measurements of damped absorbers

We present here a dataset of quasars observed with the Ultraviolet Visual Echelle Spectrograph (UVES) on the Very Large Telescope and available in the European Southern Observatory UVES Advanced Data Products archive. The sample is made up of a total of 250 high resolution quasar spectra with emission redshifts ranging from 0.191 ≤ zem ≤ 6.311. The total UVES exposure time of this dataset is 1560 h. Thanks to the high resolution of UVES spectra, it is possible to unambiguously measure the column density of absorbers with damping wings, down to N HI 10 19 cm −2 , which constitutes the sub-damped Lyα absorber (sub-DLA) threshold. Within the wavelength coverage of our UVES data, we find 150 damped Lyα systems (DLAs)/sub-DLAs in the range 1.5 < zabs < 4.7. Of these 150, 93 are DLAs and 57 are sub-DLAs. An extensive search in the literature indicates that 6 of these DLAs and 13 of these sub-DLAs have their N HI measured for the first time. Among them, 10 are new identifications as DLAs/sub-DLAs. For each of these systems, we obtain an accurate measurement of the H i column density and the absorber’s redshift in the range 1.7 < zabs < 4. 2b y implementing a Voigt profile-fitting algorithm. These absorbers are further confirmed thanks to the detection of associated metal lines and/or lines from members of the Lyman series. In our data, a few quasars’ lines-of-sight are rich. An interesting example is towards QSO J0133+0400 (zem = 4.154) with six DLAs and sub-DLAs reported.
Standard Model evaluation of $\varepsilon_K$ using lattice QCD inputs for $\hat{B}_K$ and $V_{cb}$

We report the Standard Model evaluation of the indirect CP violation parameter $\varepsilon_K$ using inputs determined from lattice QCD: the kaon bag parameter $\hat{B}_K$, $\xi_0$, $|V_{us}|$ from the $K_{\ell 3}$ and $K_{\mu 2}$ decays, and $|V_{cb}|$ from the axial current form factor for the exclusive decay $\bar{B} \to D^* \ell \bar{\nu}$ at zero-recoil. The theoretical expression for $\varepsilon_K$ is thoroughly reviewed to give an estimate of the size of the neglected corrections, including long distance effects. The Wolfenstein parametrization $(|V_{cb}|, \lambda, \bar{\rho}, \bar{\eta})$ is adopted for CKM matrix elements which enter through the short distance contribution of the box diagrams. For the central value, we take the Unitarity Triangle apex $(\bar{\rho}, \bar{\eta})$ from the angle-only fit of the UTfit collaboration and use $V_{us}$ as an independent input to fix $\lambda$. We find that the Standard Model prediction of $\varepsilon_K$ with exclusive $V_{cb}$ (lattice QCD results) is lower than the experimental value by $3.4\sigma$. However, with inclusive $V_{cb}$ (results of the heavy quark expansion), there is no gap between the Standard Model prediction of $\varepsilon_K$ and its experimental value. For the calculation of $\varepsilon_K$, we perform the renormalization group running to obtain $\eta_{cc}$ at next-to-next-to-leading-order; we find $\eta_{cc}^\mathrm{NNLO}=1.72(27)$.
Comparative Investigation of the Differences in Chemical Compounds between Raw and Processed Mume Fructus Using Plant Metabolomics Combined with Chemometrics Methods

Mume Fructus is a well-known herbal medicine and food with a long history of processing and application. Different processing methods impact the intrinsic quality of Mume Fructus. Thus, it is of great significance to investigate the changes in chemical components during processing (i.e., raw compared to the pulp and charcoal forms). In this study, plant metabolomics methods based on mass spectrometry detection were established to analyze the chemical ingredients of Mume Fructus comprehensively. Chemometric strategies were combined to analyze the profile differences of Mume Fructus after different processing methods. The established strategy identified 98 volatile and 89 non-volatile compounds of Mume Fructus by gas chromatography-mass spectrometry (GC-MS) and ultra-high performance liquid chromatography coupled with quadrupole time of flight mass spectrometry (UHPLC-Q-TOF-MS/MS), respectively. Moreover, the orthogonal partial least squares discriminant analysis (OPLS-DA) indicated that raw Mume Fructus and the Mume Fructus pulp and charcoal were distributed in three regions. Subsequently, 19 volatile and 16 non-volatile components were selected as potential chemical component markers with variable importance in the projection using (VIP) >1 as the criterion, and the accuracy was verified by a Back Propagation Neural Network (BP-NN). To further understand the difference in the content of Mume Fructus before and after processing, 16 non-volatile chemical component markers were quantitatively determined by ultra-high performance liquid chromatography-mass spectrometry (UHPLC-MS/MS). The results revealed that, compared with raw Mume Fructus, the total content of 16 components in the pulp of Mume Fructus increased while it decreased in the charcoal. Therefore, this study used GC-MS, UHPLC-Q-TOF-MS/MS and UHPLC-MS/MS modern technology to analyze the differences in chemical components before and after the processing of Mume Fructus and provided a material basis for further research on the quality evaluation and efficacy of Mume Fructus.
AN UNBIASED SPECTRAL LINE SURVEY TOWARD R CrA IRS7B IN THE 345 GHz WINDOW WITH ASTE

We have conducted a spectral line survey in the 332–364 GHz region with the Atacama Submillimeter Telescope Experiment 10 m telescope toward R CrA IRS7B, a low-mass protostar in the Class 0 or Class 0/I transitional stage. We have also performed some supplementary observations in the 450 GHz band. In total, 16 molecular species are identified in the 332–364 GHz region. Strong emission lines of CN and CCH are observed, whereas complex organic molecules and long carbon-chain molecules, which are characteristics of hot corino and warm carbon-chain chemistry (WCCC) source, respectively, are not detected. The rotation temperature of CH3OH is evaluated to be 31 K, which is significantly lower than that reported for the prototypical hot corino IRAS 16293-2422 (∼85 K). The deuterium fractionation ratios for CCH and H2CO are obtained to be 0.038 and 0.050, respectively, which are much lower than those in the hot corino. These results suggest a weak hot corino activity in R CrA IRS7B. On the other hand, the carbon-chain related molecules, CCH and c-C3H2, are found to be abundant. However, this source cannot be classified as a WCCC source, since long carbon-chain molecules are not detected. If WCCC and hot corino chemistry represent the two extremes in chemical compositions of low-mass Class 0 sources, R CrA IRS7B would be a source with a mixture of these two chemical characteristics. The UV radiation from the nearby Herbig Ae star R CrA may also affect the chemical composition. The present line survey demonstrates further chemical diversity in low-mass star-forming regions.
Forest tree dynamics from the first four years of permanent plot in Mount Papandayan, Indonesia: mortality, recruitment, and growth

A permanent plot is a powerful tool to study the vegetation’s dynamics and regeneration in the forest ecosystem. This study presents the first four-year tree vegetation monitoring in a one-hectare permanent plot established in a mixed forest of Mount Papandayan (MP) Nature Reserve, Indonesia. Besides studying the structure and floristic tree community composition in the plot, this study aims to study the changes and in mortality and growth of the tree community after four years of plot establishment. A one-hectare permanent plot was established in 2010 and all trees inside the plot with a diameter over 5 cm were tagged and measured in 2011 and 2015. There were 1,820 trees from 33 species and 20 families recorded during the first monitoring in 2011. Four years later, there were more trees recorded (1,845 trees) with an average growth rate of 1.17 cm. The mortality rate (2.8%) was lower than the recruitment rate (4.2%) and there were no changes in the domination of Distylium stellare. The results of this study will help to provide the preliminary data on actual in situ tree mortality and growth, which will help to develop a more complete tree species selection criteria for MP restoration.
A GRAND DESIGN FOR GALAXY CLUSTERS: CONNECTIONS AND PREDICTIONS

We analyze with our entropy-based Supermodel a library of 12 galaxy clusters featuring extended X-ray observations of their intracluster plasma (ICP). The few intrinsic parameters of the model—basically, the central level and the outer slope of the entropy profile—enable us to uniformly derive not only robust snapshots of the ICP thermal state, but also the “concentration” parameter marking the age of the host dark matter (DM) halo. We test these profiles for consistency with numerical simulations and observations. We find the central and the outer entropy correlate, so that these clusters split into two main classes defined on the basis of low (LE) or high entropy (HE) conditions prevailing throughout the ICP. We also find inverse correlations between the central/outer entropy and the halo concentration. We interpret these in terms of mapping the ICP progress on timescales around 5 Gyr toward higher concentrations, under the drive of the DM halo development. The progress proceeds from HE clusters to LE clusters, toward states of deeper entropy erosion by radiative cooling in the inner regions and of decreasing outer entropy production as the accretion peters out. We propose these radial and time features constitute a cluster Grand Design that we use here to derive a number of predictions. For HE clusters we predict sustained outer temperature profiles. For LEs we expect the outer entropy ramp to bend over; hence the temperature declines before steepening at low z; this feature goes together with an increasing turbulent support, a condition that can be directly probed with the Sunyaev–Zel'dovich effect. We finally discuss the looming out of two intermediate subsets: a wiggled at low z that features central temperature profiles retaining imprints of entropy discharged by active galactic nuclei or deep mergers and high-z LEs where the cosmogony/cosmology had little time to enforce a sharp outer entropy bending.
Populations of Tau Conformers Drive Prion-like Strain Effects in Alzheimer’s Disease and Related Dementias

Recent findings of diverse populations of prion-like conformers of misfolded tau protein expand the prion concept to Alzheimer’s disease (AD) and monogenic frontotemporal lobar degeneration (FTLD)-MAPT P301L, and suggest that distinct strains of misfolded proteins drive the phenotypes and progression rates in many neurodegenerative diseases. Notable progress in the previous decades has generated many lines of proof arguing that yeast, fungal, and mammalian prions determine heritable as well as infectious traits. The extraordinary phenotypic diversity of human prion diseases arises from structurally distinct prion strains that target, at different progression speeds, variable brain structures and cells. Although human prion research presents beneficial lessons and methods to study the mechanism of strain diversity of protein-only pathogens, the fundamental molecular mechanism by which tau conformers are formed and replicate in diverse tauopathies is still poorly understood. In this review, we summarize up to date advances in identification of diverse tau conformers through biophysical and cellular experimental paradigms, and the impact of heterogeneity of pathological tau strains on personalized structure- and strain-specific therapeutic approaches in major tauopathies.
HYDROGEN BALMER CONTINUUM IN SOLAR FLARES DETECTED BY THE INTERFACE REGION IMAGING SPECTROGRAPH (IRIS)

We present a novel observation of the white light flare (WLF) continuum, which was significantly enhanced during the X1 flare on 2014 March 29 (SOL2014-03-29T17:48). Data from the Interface Region Imaging Spectrograph (IRIS) in its near-UV channel show that at the peak of the continuum enhancement, the contrast at the quasi-continuum window above 2813 Å reached 100%–200% and can be even larger closer to Mg ii lines. This is fully consistent with the hydrogen recombination Balmer-continuum emission, which follows an impulsive thermal and non-thermal ionization caused by the precipitation of electron beams through the chromosphere. However, a less probable photospheric continuum enhancement cannot be excluded. The light curves of the Balmer continuum have an impulsive character with a gradual fading, similar to those detected recently in the optical region on the Solar Optical Telescope on board Hinode. This observation represents a first Balmer-continuum detection from space far beyond the Balmer limit (3646 Å), eliminating seeing effects known to complicate the WLF detection. Moreover, we use a spectral window so far unexplored for flare studies, which provides the potential to study the Balmer continuum, as well as many metallic lines appearing in emission during flares. Combined with future ground-based observations of the continuum near the Balmer limit, we will be able to disentangle various scenarios of the WLF origin. IRIS observations also provide a critical quantitative measure of the energy radiated in the Balmer continuum, which constrains various models of the energy transport and deposit during flares.
On the validity of the classical plasma conductivity in capacitive RF discharges

The plasma conductivity is an important input parameter for various plasma models. It is typically obtained from a simplified version of the electron momentum balance equation, where only a single inertia term and a simplified description of the collisional momentum transfer are included. The electric field is assumed to be a harmonic function of the driving frequency, higher harmonics of the current and spatial variations are neglected. Through particle-in-cell/Monte Carlo collision (PIC/MCC) simulations and analysis of the electric field generation based on velocity moments of the Boltzmann equation, the validity of this classical model is studied in capacitively coupled plasmas (CCPs). We find that these assumptions/simplifications result in significant inaccuracies of the conductivity in many cases. In single frequency CCPs, a deviation of more than an order of magnitude from the effective PIC-conductivity obtained from the simulations is found at low pressures in the discharge center and at the maximum sheath edge. In the center, this deviation is caused by neglecting the temperature gradient term in the momentum balance equation and adopting an approximation of the Ohmic term in the classical model, while at the maximum sheath edge it is induced by neglecting the density gradient term that accounts for the effect of the ambipolar electric field. The inaccuracy in the discharge center is reduced at higher pressures where the Ohmic term dominates and the approximations made in the classical model are more applicable. Better performance of the classical model is also found under conditions at which the inertia term included in the model plays an important role. Generally, neglecting higher harmonics of the current and spatial variations of plasma parameters is found to cause strong inaccuracies. Thus, the classical model can result in an inaccurate calculation of the power absorbed by electrons. Our results indicate that its applicability must be evaluated for a given set of conditions before using it to avoid introducing errors to plasma models.