Miracle-dz/UniFAR-FTUs huggingface dataset:
Evaluation of psychometric characteristics of light triad personality questionnaire in nurses

Personality is one of the important etiological factors of psychological factors. In this regard, one of the important factors in the success of people's social and psychological life is the light triad personality. They are a combination of sympathy, compassion, and humanity. On the basis of results of the research, it is not possible to trust the psychometrics characteristics of tools; it is necessary to evaluate the psychometric characteristics of these tools. Meanwhile, the aim of the present study is the evaluation of psychometrics characteristics of light triad personality in nurses.
Total Quality Management as Applied to Service Sector with Relevance to Indian Situations

This research paper will focus on the issues of application of the principles of Total Quality Management (TQM) to Service Industries, in general, as well as issues related to the training needs of the employees and other relevant related concerns. In today's world class initiatives, employees need to be empowered in decision-making, either as a team, or as individuals. Empowered employees who are properly and adequately guided and trained, take decisions that help to achieve the vision of the Organization. They become customer-centric.
The Compositionality of Facial Expressions

The principle of compositionality, an important postulation in language and cognition research, posits that the meaning of a complex expression is determined by the meaning of its constituting parts and the operation performed on those parts. Here, we provide strong evidence that this principle plays a significant role also in interpreting facial expressions. In three studies in which perceivers interpreted sequences of two emotional facial expression images, we show that the composite meaning of facial expressions results from the meaning of its constituting expressions and an algebraic operation performed on those expressions. Our study offers a systematic account as to how the meaning of facial expressions (single and sequences) are being formed and perceived. In a broader context, our results raise the possibility that the principle of compositionality may apply to human communication modalities beyond spoken language, whereby a minimal number of components are expanded to a much greater number of meanings.
Directions for Solving Bad Workman Practices in Power Distribution Line Connections

Standardization of the process of power line connector installation and proper die selection technique for compression connectors is essential for power system reliability improvements. This paper presents an attempt to identify good workman practices required for making proper power distribution line connections. This will be a guide in the assembly and preventive maintenance of efficient electrical connections for power distribution circuits. Data and experience gained through usage of power line connectors by Ceylon Electricity Board is the basis of this study. Properties of conductor metals and metal oxides illustrate the requirements of standardized methods of making connections. Requirements for the proper selection of connectors; the proper preparation of conductors; and the proper application of fusion, compression, and bolted connectors are identified. Standards available on power line connectors are given. Photographs of bad workman practices are included with explanations. Mathematical formulas are developed for calculating the correct die size for compression connectors. Performance identification of any type of connector installed in a power line is carried out by thermal imaging. Thermal images taken from a few installed connectors are included and a procedure for assessing connector performance is suggested.
Minimizing the Ex Vivo Confounds of Cell-Isolation Techniques on Transcriptomic and Translatomic Profiles of Purified Microglia

Visual Abstract Modern molecular and biochemical neuroscience studies require analysis of specific cellular populations derived from brain tissue samples to disambiguate cell type-specific events. This is particularly true in the analysis of minority glial populations in the brain, such as microglia, which may be obscured in whole tissue analyses. Microglia have central functions in development, aging, and neurodegeneration and are a current focus of neuroscience research. A long-standing concern for glial biologists using in vivo models is whether cell isolation from CNS tissue could introduce ex vivo artifacts in microglia, which respond quickly to changes in the environment. Mouse microglia were purified by magnetic-activated cell sorting (MACS), as well as cytometer-based and cartridge-based fluorescence-activated cell sorting (FACS) approaches to compare and contrast performance. The Cx3cr1-NuTRAP mouse model was used to provide an endogenous fluorescent microglial marker and a microglial-specific translatome profile as a baseline comparison lacking cell isolation artifacts. All sorting methods performed similarly for microglial purity with main differences being in cell yield and time of isolation. Ex vivo activation signatures occurred principally during the initial tissue dissociation and cell preparation and not the cell sorting. The cell preparation-induced activational phenotype could be minimized by inclusion of transcriptional and translational inhibitors or non-enzymatic dissociation conducted entirely at low temperatures. These data demonstrate that a variety of microglial isolation approaches can be used, depending on experimental needs, and that inhibitor cocktails are effective at reducing cell preparation artifacts.
Breaking the Structure of Liquid Hydrogenated Alcohols Using Perfluorinated tert-Butanol: A Multitechnique Approach (Infrared, Raman, and X-ray Scattering) Analyzed by DFT and Molecular Dynamics Calculations

The state of aggregation at room temperature of tert-butanol (TBH) and perfluoro tert-butanol (TBF) liquid mixtures is assessed by vibrational spectroscopy (Raman and infrared) and X-ray diffraction and analyzed using density functional theory (DFT) and molecular dynamics (MD) simulations. It is shown that larger clusters (mostly tetramers) of TBH are destroyed upon dilution with TBF. Small oligomers, monomers, and mainly heterodimers are present at the equimolar concentration. At variance with slightly interacting solvents, the signature of hetero-oligomers is shown by the appearance of a new broad band detected in the infrared region. The same spectral observation is detected for mixtures of other hydrogenated alcohols (methanol and 1-butanol). The new infrared feature is unaffected by dilution in a polar solvent (CDCl3) in a high-concentration domain, allowing us to assign it to the signature of small hetero-oligomers. MD simulations are used to assess the nature of the species present in the mixture (monomers and small hetero-oligomers) and to follow the evolution of their population upon the dilution. Combining MD simulations with DFT calculations, the infrared spectral profile is successfully analyzed in equimolecular mixtures. This study shows that TBF is a structure breaker of hydrogen-bonded alcohol networks and that the TBF (donor)–TBH (acceptor) heterodimer is the dominant species in an extended range of concentration, centered in the vicinity of the equimolar fraction.
Associations between Conflict Negotiation Strategies, Sexual Comfort, and Sexual Satisfaction in Adolescent Romantic Relationships

ABSTRACT Achieving healthy and satisfying sexual relationships is a major developmental task in adolescence, but factors promoting sexual satisfaction among adolescent romantic relationships remain underexplored. Since sexuality is shaped by relational experiences, strategies mobilized to negotiate conflicts in romantic relationships could be related to sexual satisfaction through comfort in negotiating sexual experiences. Sexual comfort refers to the ease of discussing sexuality, and feeling comfortable with one’s own sexual life and with others’ sexual behaviors. This cross-sectional dyadic study examined the mediating role of sexual comfort in the associations between perceived conflict negotiation strategies and sexual satisfaction among adolescent romantic dyads. The actor-partner interdependence model guided the analyses of self-reported questionnaires from 104 mixed- and same-sex dyads (Mage = 18.99 years, SD = 1.51). An adolescent’s higher compromise and lower submission were related to their own higher sexual satisfaction via their own higher sexual comfort. The results also revealed a direct association between an adolescent’s higher domination and their own lower sexual satisfaction. These findings underscore the importance of considering conflict negotiation strategies and sexual comfort as key factors related to adolescents’ sexual satisfaction.
Emerging histopathologic markers in early‐stage oral tongue cancer: A systematic review and meta‐analysis

Although there are many histopathologic prognosticators, grading of early oral tongue squamous cell carcinoma (OTSCC) is still based on morphological cell differentiation which has low prognostic value. Here we summarize the emerging histopathological markers showing powerful prognostic value, but are not included in pathology reports. Using PubMed, Scopus, Ovid Medline, and Web of Science databases, a systematic literature search was preformed to identify early OTSCC studies that investigated the prognostic significance of hematoxylin–eosin‐based histopathologic markers. Our meta‐analysis showed that tumor budding was associated with overall survival (hazard ratio [HR] 2.32; 95% CI 1.40–3.84; p < 0.01) and disease‐specific survival (DSS) (1.89; 95% CI 1.13–3.15; p = 0.02). Worst pattern of invasion was associated with disease‐free survival (DFS) (1.95; 95% CI 1.04–3.64; p = 0.04). Tumor–stroma ratio was also associated with DFS (1.75, 95% CI 1.24–2.48; p < 0.01) and DSS (1.69; 95% CI 1.19–2.42; p < 0.01). Tumor budding, worst pattern of invasion, and tumor–stroma ratio have a promising prognostic value in early OTSCC. The evaluation and reporting of these markers is cost‐effective and can be incorporated in daily practice.
Development of Cancer Among Patients With Pediatric-Onset Inflammatory Bowel Disease

Key Points Question What is the risk of cancer among patients with pediatric-onset inflammatory bowel disease (IBD)? Findings This meta-analysis of 5 unselected, population-based cohort studies comprising 19 812 individuals found a 2.4-fold increased rate of cancer among patients with pediatric-onset IBD, which was primarily due to gastrointestinal cancers. The absolute rate of cancer among patients with pediatric-onset IBD is low. Meaning These results suggest that there is a greater than 2-fold increased rate of cancer among patients with pediatric-onset IBD compared with general pediatric populations, due primarily to an increased rate of gastrointestinal cancers.
Aspiration pneumonia and anesthesia techniques in hip fracture surgery in elderly patients: A retrospective cohort study using administrative data

Purpose: Aspiration pneumonia is a critical issue. General anesthesia may suppress the airway’s protective reflex. However, aspiration pneumonia is also observed in patients who undergo hip fracture surgery under spinal anesthesia. The aim of this study was to investigate the relationship between anesthesia methods and aspiration pneumonia as well as the predictive factors of aspiration pneumonia in elderly patients undergoing hip fracture surgery. Methods: The medical records of 19,809 patients aged ≥60 years who underwent hip fracture surgery under general or spinal anesthesia were reviewed. After propensity score matching, the anesthesia methods affecting the occurrences of aspiration pneumonia and other complications were investigated via logistic regression and instrumental variable analyses. Predictive factors of aspiration pneumonia were also investigated in all subjects using a multivariable logistic regression analysis. Results: Among the 11,673 general anesthesia patients and 8136 spinal anesthesia patients, aspiration pneumonia occurred in 356 patients (1.8%). Post-propensity score matching the incidences of aspiration pneumonia with general and spinal anesthesia were 1.8% and 1.5%, respectively (p = 0.158); other pulmonary complications were 1.5% and 1.5%, respectively (p = 0.893); and the mortality rates were 1.4% and 1.2%, respectively (p = 0.219). The predictive factors of aspiration pneumonia were advanced age, male sex, lean body, cerebrovascular disease, dementia, and dependency for activities of daily living (eating). Conclusion: Spinal and general anesthesia showed similar incidences of aspiration pneumonia in elderly hip fracture surgery. Regardless of the anesthesia method, great care should be taken, especially in elderly patients with the identified predictive factors.
Are We in Control of Our Demons?

Background The medical profession, with its remarkable physical and emotional demands, predisposes physicians to compassion fatigue (CF) and burnout (BO). Although these conditions have been studied individually, little attention has been paid to how pediatric emergency physicians experience these conditions in the context of an Asian emergency setting especially during a global pandemic In our study, we aim to understand the experiences of individual physicians and describe the potential triggers or protective factors of compassion satisfaction, BO, and compassion satisfaction among physicians in an Asian pediatric emergency department during a pandemic. Methods A qualitative, individual interview methodology was used. From March to April 2020, we enrolled 20 physicians involved in frontline care during the coronavirus disease 2019 (COVID-19) pandemic in the pediatric emergency department to participate. Semistructured interviews were conducted, audiotaped, and transcribed in verbatim, with identifiers removed. Themes were identified, and data were analyzed using qualitative data analysis and iterative data analysis. Results We recruited 20 physicians. Three themes emerged from data analysis. First, we showed how workplace conditions are protective, including work morale, leadership and management, and social support received. Second, workload affected participants emotionally and in terms of its heavier quantity and longer hours. Finally, intrinsic factors that were protective in developing CF or BO include having professional autonomy, experience, work-life balance, and having emotional resilience to develop self-care. Cultural influences affect emotional regulation and can lead to negative coping with negative peer pressure. In general, participants quantified their levels of satisfaction at work as average to above average. However, they highlighted experiencing greater stress during COVID-19 with the underlying fear of contagion and infection. Conclusions Being a pediatric emergency physician puts one at greater risk of experiencing CF and BO because of work and nonwork stressors, especially during a global pandemic, influenced by sociocultural factors. A positive and supportive work environment should be created while providing culturally adapted strategies to improve individual physician resilience to maintain their well-being.
Patient and practitioner views on a combined face-to-face and digital intervention to support medication adherence in hypertension: a qualitative study within primary care

Objectives To explore patients’ and healthcare practitioners’ (HCPs) views about non-adherence to hypertension medication and potential content of a combined very brief face-to-face discussion (VBI) and digital intervention (DI). Methods A qualitative study (N=31): interviews with patients with hypertension (n=6) and HCPs (n=11) and four focus groups with patients with hypertension (n=14). Participants were recruited through general practices in Eastern England and London. Topic guides explored reasons for medication non-adherence and attitudes towards a potential intervention to support adherence. Stimuli to facilitate discussion included example SMS messages and smartphone app features, including mobile sensing. Analysis was informed methodologically by the constant comparative approach and theoretically by perceptions and practicalities approach. Results Participants’ overarching explanations for non-adherence were non-intentional (forgetting) and intentional (concerns about side effects, reluctance to medicate). These underpinned their views on intervention components: messages that targeted forgetting medication or obtaining prescriptions were considered more useful than messages providing information on consequences of non-adherence. Tailoring the DI to the individuals’ needs, regarding timing and number of messages, was considered important for user engagement. Patients wanted control over the DI and information about data use associated with any location sensing. While the DI was considered limited in its potential to address intentional non-adherence, HCPs saw the potential for a VBI in addressing this gap, if conducted in a non-judgemental manner. Incorporating a VBI into routine primary care was considered feasible, provided it complemented existing GP practice software and HCPs received sufficient training. Conclusions A combined VBI-DI can potentially address intentional and non-intentional reasons for non-adherence to hypertension medication. For optimal engagement, recommendations from this work include a VBI conducted in a non-judgmental manner and focusing on non-intentional factors, followed by a DI that is easy-to-use, highly tailored and with provision of data privacy details about any sensing technology used.
National experience with living donor liver transplantation for hepatocellular carcinoma

Living donor liver transplantation (LDLT) is an attractive option to decrease waitlist dropout, particularly for patients with hepatocellular carcinoma (HCC) who face lengthening waiting times. Using the United Network for Organ Sharing (UNOS) national database, trends in LDLT utilization for patients with HCC were evaluated, and post‐LT outcomes for LDLT versus deceased donor liver transplantation (DDLT) were compared. From 1998 to 2018, LT was performed in 20,161 patients with HCC including 726 (3.6%) who received LDLT. The highest LDLT utilization was prior to the 2002 HCC Model for End‐Stage Liver Disease (MELD) exception policy (17.5%) and dropped thereafter (3.1%) with a slight increase following the 6‐month wait policy in 2015 (3.8%). LDLT was more common in patients from long‐wait UNOS regions with blood type O, in those with larger total tumor diameter (2.3 vs. 2.1 cm, p = 0.02), and higher alpha‐fetoprotein at LT (11.5 vs. 9.0 ng/ml, p = 0.04). The 5‐year post‐LT survival (LDLT 77% vs. DDLT 75%), graft survival (72% vs. 72%), and HCC recurrence (11% vs. 13%) were similar between groups (all p > 0.20). In conclusion, LDLT utilization for HCC has remained low since 2002 with only a slight increase after the 6‐month wait policy introduction in 2015. Given the excellent post‐LT survival, LDLT appears to be an underutilized but valuable option for patients with HCC, especially those at high risk for waitlist dropout.
RGI‐GOLVEN signaling promotes cell surface immune receptor abundance to regulate plant immunity

Plant immune responses must be tightly controlled for proper allocation of resources for growth and development. In plants, endogenous signaling peptides regulate developmental and growth‐related processes. Recent research indicates that some of these peptides also have regulatory functions in the control of plant immune responses. This classifies these peptides as phytocytokines as they show analogies with metazoan cytokines. However, the mechanistic basis for phytocytokine‐mediated regulation of plant immunity remains largely elusive. Here, we identify GOLVEN2 (GLV2) peptides as phytocytokines in Arabidopsis thaliana. GLV2 signaling enhances sensitivity of plants to elicitation with immunogenic bacterial elicitors and contributes to resistance against virulent bacterial pathogens. GLV2 is perceived by ROOT MERISTEM GROWTH FACTOR 1 INSENSITIVE (RGI) receptors. RGI mutants show reduced elicitor sensitivity and enhanced susceptibility to bacterial infection. RGI3 forms ligand‐induced complexes with the pattern recognition receptor (PRR) FLAGELLIN SENSITIVE 2 (FLS2), suggesting that RGIs are part of PRR signaling platforms. GLV2‐RGI signaling promotes PRR abundance independent of transcriptional regulation and controls plant immunity via a previously undescribed mechanism of phytocytokine activity.
Preoperative electroacupuncture for postoperative nausea and vomiting in laparoscopic gynecological surgery: a randomized controlled trial

Objective: We aimed to evaluate the effectiveness and safety of preoperative electroacupuncture (EA) on the incidence of postoperative nausea and vomiting (PONV), and severity of postoperative pain, in gynecological patients undergoing laparoscopic surgery. The effects of EA administered at different preoperative time points were compared. Methods: A total of 413 patients undergoing elective laparoscopic gynecological surgery were randomly allocated into 4 groups receiving EA the day before surgery (Group Pre, n = 103), 30 min before (Group 30, n = 104) or both (Group Comb, n = 103), or usual care alone (Group Usual, n = 103). All acupuncture groups had usual care. The incidence of PONV and pain at 24 h were primary outcomes. Secondary outcomes included the severity of postoperative nausea, vomiting and pain, requirement for antiemetic medication and quality of recovery (QoR)-15 scores after surgery. Results: There were significant differences between the four groups in nausea and vomiting incidence (0–24 h), postoperative antiemetic use (0–48 h), and postoperative pain (0–6 h), with the EA groups recording the lowest levels. Regarding primary outcomes, incidence of nausea and vomiting at 6-24 h was 28/11/18/11% (p = 0.003) 23/5/8/9% (p < 0.001), respectively, for Groups Usual/Pre/30/Comb. Accordingly, EA reduced the incidence of nausea and vomiting at 6-24 h by 61/34/60% and 79/65/61% for Groups Pre/30/Comb, respectively. Regarding secondary outcomes, incidence of nausea and vomiting at 0-6 h was 20/9/11/7% (p = 0.013) and 17/7/9/6% (p = 0.021), respectively, for Groups Usual/Pre/30/Comb. Rescue antiemetics at 0–6 h were required by 18/4/11/4% (p = 0.001) in Groups Usual/Pre/30/Comb. The mean numerical rating scale (NRS) pain score (0–10) at 0–6 h was significantly different between groups (2.45/1.89/2.01/1.97 for Groups Usual/Pre/30/Comb, p = 0.024). There were no significant differences between the three EA-treated groups. Conclusion: In gynecological patients undergoing laparoscopic surgery and treated with multimodal antiemetic methods, one session of preoperative EA may be a safe adjunctive treatment for PONV prophylaxis. Optimal timing of EA requires further verification. Trial registration number: ChiCTR-INR-16010035 (Chinese Clinical Trial Registry).