Miracle-dz/UniFAR-FTUs huggingface dataset:
Multi-messenger observations of a binary neutron star merger

On 2017 August 17 a binary neutron star coalescence candidate (later designated GW170817) with merger time 12:41:04 UTC was observed through gravitational waves by the Advanced LIGO and Advanced Virgo detectors. The Fermi Gamma-ray Burst Monitor independently detected a gamma-ray burst (GRB 170817A) with a time delay of $\sim 1.7\,{\rm{s}}$ with respect to the merger time. From the gravitational-wave signal, the source was initially localized to a sky region of 31 deg2 at a luminosity distance of ${40}_{-8}^{+8}$ Mpc and with component masses consistent with neutron stars. The component masses were later measured to be in the range 0.86 to 2.26 $\,{M}_{\odot }$. An extensive observing campaign was launched across the electromagnetic spectrum leading to the discovery of a bright optical transient (SSS17a, now with the IAU identification of AT 2017gfo) in NGC 4993 (at $\sim 40\,{\rm{Mpc}}$) less than 11 hours after the merger by the One-Meter, Two Hemisphere (1M2H) team using the 1 m Swope Telescope. The optical transient was independently detected by multiple teams within an hour. Subsequent observations targeted the object and its environment. Early ultraviolet observations revealed a blue transient that faded within 48 hours. Optical and infrared observations showed a redward evolution over ~10 days. Following early non-detections, X-ray and radio emission were discovered at the transient's position $\sim 9$ and $\sim 16$ days, respectively, after the merger. Both the X-ray and radio emission likely arise from a physical process that is distinct from the one that generates the UV/optical/near-infrared emission. No ultra-high-energy gamma-rays and no neutrino candidates consistent with the source were found in follow-up searches. These observations support the hypothesis that GW170817 was produced by the merger of two neutron stars in NGC 4993 followed by a short gamma-ray burst (GRB 170817A) and a kilonova/macronova powered by the radioactive decay of r-process nuclei synthesized in the ejecta.
Basic Neurochemistry: Molecular, Cellular and Medical Aspects

Part 1 Neural membranes: neurocellular anatomy cell membrane structure and functions membrane transport electrical excitability and ion channels lipids myelin formation, structure and biochemistry molecular biology of vision olfaction and taste in vertebrates - molecular and organizational strategies underlying perception. Part 2 Synaptic function: chemically mediated synaptic transmission - an overview receptors and signal transduction - classification and quantitation acetylcholine catecholamines serotonin histamine opioid peptides and opioid receptors neuropeptides excitatory amino acid transmitters GABA and glycine purinergic systems phosphoinositides G-proteins and cyclic nucleotides in the nervous system protein phosphorylation and the regulation of neuronal function eicosanoids. Part 3 Molecular neurobiology: gene expression in the mammalian nervous system molecular probes for gene expression molecular genetic approaches to inherited neurological. Part 4 Cellular neurochemistry: degenerative disorders axonal transport and the neuronal cytoskeleton development of the nervous system neural plasticity and regeneration biochemistry of aging in the mammaliam brain circulation and energy metabolism of the brain blood-brain-cerebrospinal fluid barrier. Part 5 Medical neurochemistry: the muscle fibre and disorders of muscle excitability diseases of carbohydrate, fatty acid, and mitochondrial metabolism vitamin and nutritional deficiencies biochemistry of neuropathy diseases involving myelin genetic disorders of lipid, glycoprotein, and mucopolysaccharide metabolism disorders of amino acid metabolism metabolic encephalopathies and coma molecular targets of abused drugs ischemia and hypoxia epileptic seizures neurotransmitters and disorders of the basal ganglia biochemistry of Alzheimer's disease positron emission tomography. Part 6 Behavioural neurochemistry: biochemical aspects of the psychotic disorders biochemical hypotheses of mood and anxiety endocrine effects on the brain and their relationships to behaviour learning and memory.
Advanced Lanczos methods for large-scale matrix problems

• A submitted manuscript is the author's version of the article upon submission and before peer-review. There can be important differences between the submitted version and the official published version of record. People interested in the research are advised to contact the author for the final version of the publication, or visit the DOI to the publisher's website. • The final author version and the galley proof are versions of the publication after peer review. • The final published version features the final layout of the paper including the volume, issue and page numbers.
Bridging the Gap Between theory and practice In life of Muslims today

Abstract Today, the world is experiencing a state of perplexity about the situation of Muslims from all aspects. The social, educational, and economic policies of the Islamic world show a great deal of contradiction between the theoretical religious teachings and the ground realities; which often depict our worldly and materialistic approach to these teachings. Muslim communities are in desperate need of rectifying their lived reality, to eliminate this estrangement between the theory and the reality. This study recommends some measures towards bridging the gap between theory and practical application of the Islamic teachings in the lives of Muslims today. As life of Prophet Mohammad is exemplary, this study deduced recommendations from his life. It is required to activate the Role of Educational Institutions, Revise the School Curriculum, Launching of Prophetic Encyclopedia in Foreign Languages and creation of awareness through Media Institutions to narrow the gap. Keywords : Bridging gap, Theory, Practice, Muslim Communities الملخص: واليوم، يشهد العالم حالة من الحيرة إزاء وضع المسلمين من جميع الجوانب. إن السياسات الاجتماعية والتعليمية والاقتصادية في العالم الإسلامي تظهر قدرا كبيرا من التناقض بين التعاليم الدينية النظرية والواقع الأرضي؛ والتي غالبا ما تصور نهجنا الدنيوي والمادي لهذه التعاليم. إن المجتمعات المسلمة في حاجة ماسة إلى تصحيح واقعها المعيشي، للقضاء على هذا التباعد بين النظرية والواقع. توصي هذه الدراسة ببعض التدابير نحو سد الفجوة بين النظرية والتطبيق العملي للتعاليم الإسلامية في حياة المسلمين اليوم. وبما أن حياة النبي محمد مثالية، استنتجت هذه الدراسة توصيات من حياته. ومن المطلوب تفعيل دور المؤسسات التربوية وتنقيح المناهج المدرسية وإطلاق موسوعة النبوة في اللغات الأجنبية وإذكاء الوعي من خلال المؤسسات الإعلامية لتضييق الفجوة. الكلمات المفتاحية : سد الفجوة، نظرية، الممارسة، المجتمعات الإسلامية
Investigations on the physiology and molecular basis of polyphosphate hyper- and hypo-accumulation in Saccharomyces cerevisiae

Background: Inorganic polyphosphate (poly P) occurs universally in all organisms from bacteria to man. It functions for example as a phosphate and energy store, and is involved in the activation and regulation of proteins. Despite its ubiquitous occurrence and important functions it is unclear how poly P is synthesized or how poly P metabolism is regulated in higher eukaryotes. This work describes a systematic analysis of poly P levels in yeast knockout strains mutated in almost every non-essential gene. Results: After three consecutive screens, 255 genes (almost 4% of the yeast genome) were found to be involved in the maintenance of normal poly P content. Many of these genes encoded proteins functioning in the cytoplasm, the vacuole or in transport and transcription. Besides reduced poly P content, many strains also exhibited reduced total phosphate content, showed altered ATP and glycogen levels and were disturbed in the secretion of acid phosphatase. Conclusions: Cellular energy and phosphate homeostasis is suggested to result from the equilibrium between poly P, ATP and free phosphate within the cell. Poly P serves as a buffer for both ATP and free phosphate levels and is therefore the least essential and consequently most variable component in this network. However, strains with reduced poly P levels are not only affected in their ATP and phosphate content, but also in other components that depend on ATP or free phosphate content, such as glycogen or secreted phosphatase activity. Systematic screening of polyphosphate levels in yeast mutant cells reveals strong interdependence with primary metabolism
T4 RNA Ligase

Description : T4 RNA Ligase ligates 5'-P oligonucleotides with 3'-OH oligonucleotides. 1) It requires ATP as cofactor. Its smallest substrates are pNp and NpNpNOH, and its reaction rate (ligation efficiency) depends on the kinds of bases involved. 1) In addition to RNA and RNA, 2) it can also ligate DNA and RNA, although only slowly. 3) The ligation rate of DNA to DNA is extremely slow, and this ligase almost fails to recognize double-stranded nucleic acids.
Habitat selection of adult moose Alces alces at two spatial scales in central Finland

The habitat selection criteria of moose Alces alces at several scales are the basic sets of information needed in moose management planning. We studied moose habitat use in central Finland during 1993–1996 using data from radio collared moose, satellite image based forest and land cover data, and applied the principles of compositional analysis. The habitat compositions of 54 home ranges (10 males during summer, six males during winter, 23 females during summer and 15 females during winter) were first compared with the overall landscape. The habitat compositions around moose locations within their home ranges were then compared with the habitat composition of the home range. Seasons and sexes were compared at both scales. In summer, there was only a slight difference between moose home ranges and the overall landscape. Based on tree species composition, home ranges are located in slightly more fertile areas than the overall landscape. Within their home ranges, moose favoured non-pine dominated habitats and mature forests, and avoided human settlements. In winter, the moose home ranges included significantly more pine-dominated plantations and other young successional stages than the overall landscape. The role of pine-dominated peatland forests/ shrub land was especially pronounced in winter. Winter home ranges included less agricultural land and human settlements than the overall landscape, probably due to the more distant location of important winter habitats from man-made landscapes. Within the home ranges, both sexes used non-pine dominated habitats more, and mature forests and human settlements less than expected. At the home range scale, there were no statistical differences between the sexes with respect to habitat use in either season. Within their home ranges, males and females used slightly different habitats during both seasons, suggesting spatially segregated habitat use by the individual sexes. The difference is more clear in winter when males tend to use more pine-dominated, young successional habitats than females. Compared to the situation in the summer, winter ranges are located in slightly more pine-dominated habitats with fewer settlements and agricultural fields. The shift in habitat use between the two seasons is more pronounced with respect to habitat use within the home range. Our results indicate that moose habitat selection criteria vary among different hierarchical levels of selection. We stress the importance of multi-scale assessment of the habitat and other resource selection of animals.
Comparison of bioactivity between sulforaphane and neoglucobrassicin hydrolysis product in murine and human cell lines (372.5)

Although the biological activity of some glucosinolate (GSL) hydrolysis products from Brassica vegetables has been extensively studied, the activity of others, such as the hydrolysis product of the indole GSL neoglucobrassicin (hNeo), is relatively unknown. Here, we aim to determine how sulforaphane (SF) and hNeo act in human and murine cell lines, regarding induction of the phase II enzyme Quinone reductase (NQO1) and inhibition of nitrite (NO) generation. Haack and colleagues reported that hNeo inhibits the effect of SF on NQO1 induction in human HepG2 cells (Haack et al., 2010). Here, we confirm this and extend our knowledge to show that hNeo causes upregulation of NQO1 alone and does not inhibit SF induction of NQO1 in murine hepatoma cells. Furthermore, this species difference is reflected in phorbol 12‐myristate 13‐acetate (PMA) induced human monocytes (THP1) and in murine RAW 264.7 macrophages, where hNeo is inhibitory in human cells but additive in murine cells, both for NQO1 induction and inhibition of NO generation. These findings suggest that the mouse may not be a robust model for evaluating the human response to bioactive compounds from Brassica.
Application of neural networks and other machine learning algorithms to DNA sequence analysis

In this article we report initial, quantitative results on application of simple neutral networks, and simple machine learning methods, to two problems in DNA sequence analysis. The two problems we consider are: (1) determination of whether procaryotic and eucaryotic DNA sequences segments are translated to protein. An accuracy of 99.4% is reported for procaryotic DNA (E. coli) and 98.4% for eucaryotic DNA (H. Sapiens genes known to be expressed in liver); (2) determination of whether eucaryotic DNA sequence segments containing the dinucleotides ''AG'' or ''GT'' are transcribed to RNA splice junctions. Accuracy of 91.2% was achieved on intron/exon splice junctions (acceptor sites) and 92.8% on exon/intron splice junctions (donor sites). The solution of these two problems, by use of information processing algorithms operating on unannotated base sequences and without recourse to biological laboratory work, is relevant to the Human Genome Project. A variety of neural network, machine learning, and information theoretic algorithms are used. The accuracies obtained exceed those of previous investigations for which quantitative results are available in the literature. They result from an ongoing program of research that applies machine learning algorithms to the problem of determining biological function of DNA sequences. Some predictions of possible new genesmore » using these methods are listed -- although a complete survey of the H. sapiens and E. coli sections of GenBank will be given elsewhere. 36 refs., 6 figs., 6 tabs. « less
The application of Shakespeare's drama in English major teaching from the perspective of social constructivist model

Social constructivism teaching model is derived based on constructivism, English teaching is an important part of higher education, with the society for high-quality compound application talent demand increasing, knowledge of English application ability of students has become the focus of attention of the problem of higher education for English majors. Shakespeare is a classic drama in English literature, the English and English in specialized teaching can apply specific teaching situation, realize students' comprehensive learning ability, based on the social constructivist model from the perspective of Shakespeare's in-depth research in the application of English teaching, the teaching present situation analysis, social construction of English majors from the viewpoint of the teaching mode of English major construction, Shakespeare plays in the English teaching mode of the application program, designed to promote the teaching level of English Majors upgrading.
Aalto system for the 2017 Arabic multi-genre broadcast challenge

We describe the speech recognition systems we have created for MGB-3, the 3rd Multi Genre Broadcast challenge, which this year consisted of a task of building a system for transcribing Egyptian Dialect Arabic speech, using a big audio corpus of primarily Modern Standard Arabic speech and only a small amount (5 hours) of Egyptian adaptation data. Our system, which was a combination of different acoustic models, language models and lexical units, achieved a Multi-Reference Word Error Rate of 29.25%, which was the lowest in the competition. Also on the old MGB-2 task, which was run again to indicate progress, we achieved the lowest error rate: 13.2%. The result is a combination of the application of state-of-the-art speech recognition methods such as simple dialect adaptation for a Time-Delay Neural Network (TDNN) acoustic model (−27% errors compared to the baseline), Recurrent Neural Network Language Model (RNNLM) rescoring (an additional −5%), and system combination with Minimum Bayes Risk (MBR) decoding (yet another −10%). We also explored the use of morph and character language models, which was particularly beneficial in providing a rich pool of systems for the MBR decoding.
Dynamic Intention-Aware Recommendation with Self-A ention

Predicting the missing values given the observed interaction matrix is a predominant task in the recommendation research eld, which is well-suited to the case when long-term user preference is considered. However, ignoring timestamp information makes it impossible to detect interest dris of individual users over time, while in many practical applications, both long and short term intents are critical to the success of recommendation algorithms. In this paper, we aim to tackle the sequential recommendation problem by modelling these two types of intents in an integrated manner. Our model is structured into two components, one for short-term intents learning and the other one for long-term preference modeling. We propose capturing user’s short term interest with a self-aention mechanism which aends over the past behaviours in a supervised learning approach. e model is nally learned in a metric learning framework, which could overcome the weakness of dot product. Experiments on a wide range of datasets on dierent domains demonstrate that our approach outperforms the state-of-the-art by a wide margin.
Analisis Peningkatan Faktor Keamanan Lereng Pada Areal Bekas Tambang Pasir Dan Batu di Desa Ngablak, Kecamatan Cluwak, Kabupaten Pati

Management of post mining land become serious concern for government in current time. Post miningarea that located in Ngablak village, Cluwak districts of Pati is one of post mining areas that did notmanaged and creates problems to civilian and village government, for example are safety andenvironment problems. Safety of environment disturbed because of mining activities that finished andcreated unstable slope (potentially landslide) caused by land dredging. To solve this problems,government need to make some research about stability of slope and studies about method ofanalysis which can increase the safety factor of slope. Slope stability analysis can be done with Side6.0 software which needs laboratory result data of soil mechanics. Methods that can increase slope’ssafety factor can be installation of retaining wall and cut and fill method that make the slope becometerraces. Efficiency of method that will be selected, can be tested by using Slide 6.0 software.Installation of retaining wall could increase the safety factor’s value become 1.103, this valuerepresents that the slope is still potentially to be landslide. However, cut and fill can increases safetyfactor’s value become 1.330, that representing slope condition is stable and safe.
Differential Involvement of Src Family Kinases in Fcγ Receptor-Mediated Phagocytosis1

The tyrosine phosphorylation cascade originated from Fcγ receptors (FcγRs) is essential for macrophage functions including phagocytosis. Although the initial step is ascribed to Src family tyrosine kinases, the role of individual kinases in phagocytosis signaling is still to be determined. In reconstitution experiments, we first showed that expression in the RAW 264.7 cell line of C-terminal Src kinase (Csk) inhibited and that of a membrane-anchored, gain-of-function Csk abolished the FcγR-mediated signaling that leads to phagocytosis in a kinase-dependent manner. We next tested reconstruction of the signaling in the membrane-anchored, gain-of-function Csk-expressing cells by introducing Src family kinases the C-terminal negative regulatory sequence of which was replaced with a c-myc epitope. Those constructs derived from Lyn and Hck (a-Lyn and a-Hck) that associated with detergent-resistant membranes successfully reconstructed FcγR-mediated Syk activation, filamentous actin rearrangement, and phagocytosis. In contrast, c-Src-derived construct (a-Src), that was excluded from detergent-resistant membranes, could not restore the series of phagocytosis signaling. Tyrosine phosphorylation of Vav and c-Cbl was restored in common by a-Lyn, a-Hck, and a-Src, but FcγRIIB tyrosine phosphorylation, which is implicated in negative signaling, was reconstituted solely by a-Lyn and a-Hck. These findings suggest that Src family kinases are differentially involved in FcγR-signaling and that selective kinases including Lyn and Hck are able to fully transduce phagocytotic signaling.
Seed bank characteristics of Dutch plant communities

With the recent appearances of a new and well-documented classification of the Dutch plant communities (Schaminee et al 1995a,b; 1996) and a database on the seed longevity of plant species of North West Europe (Thompson ct al. 1997a) it was possible to investigate patterns of seed longevity in Dutch plant communities, considering the frequencies of plant species in various communities. This study revealed that arable weed communities have long-lived seeds compared to the transient seed bank of deciduous woodland; species-rich grassland communities tend to have a short-lived soil seed bank, intermediate between the latter two communities, Moreover, the present study showed that significant differences in community longevity exist between weed communities as well as between grassland communities. The approach based on soil seed bank spectra of plant communities gives support to existing phytosociological theories on different strategies of plant communities sensu Stortelder (1992) and Schaminee & Stortelder (1996). The information on seed longevity of communities is essential to the practice of nature conservation and nature development because it reveals the possible vulnerability of plant communities to extinction, including their soil seed banks, the necessity of their conservation and their possibilities for regeneration.