Miracle-dz/UniFAR-FTUs huggingface dataset:
The Modern Swedish National Seismic Network: Two Decades of Intraplate Microseismic Observation

The Swedish National Seismic Network (SNSN) was modernized and rapidly expanded during the period 1998–2012. The network currently operates 68 permanent seismic stations, all with broadband instruments supplying real-time continuous data at 100 samples per second. Continuous data from 10 stations are shared with the international community via Orfeus, and approximately 10 stations of their individual choice are shared with institutes in neighboring countries (Denmark, Finland, Norway, and Germany). The SNSN uses the South Iceland Lowland (SIL) system as the primary system for automatic detection and event definition. In addition, an in-house system based on migration and stacking is used for automatic detection of small events, and implementations of SeisComP (SC) and Earthworm are used primarily for rapid detection of larger regional events. Global monitoring is performed with SC, using approximately 250 global stations, and we operate a continuous rapid risk assessment system serving Swedish crisis management authorities. Since the start of automatic processing in August 2000, the SNSN has recorded and interactively analyzed more than 171,000 seismic events, of which 10,700 were earthquakes with local magnitudes ranging from around −1 to 4.3. The microearthquake activity detected in the last 20 yr has significantly improved the identification and understanding of seismically active structures in Sweden.
A Study on the Effect of Personality Traits and Social Support on Psychological Health of Chinese College Students Based on Data Mining Technology

Background With the continuous development of the society, the pace of life is accelerating, psychological health has become an important factor affecting people's quality of life. Domestic studies have shown that mental diseases have become an important cause of College Students' sick leave, withdrawal, addiction, crime and suicide. Personality traits and social support factors have been considered to be related to psychological health. Methods In this study, Symptom Checklist-90 (SCL-90), Eysenck Personality Questionaire (EPQ) and Perceived Social Support Scale (PSSS) of some freshmen in 2020 were randomly selected from the psychological census database of a university in China as the research data. The decision tree algorithm was used to establish a predictive model for psychological health related personality straits and social support factors of college students. In association analysis, we got the most closely effect factors with psychological health or psychological abnormality by analyzing important association rules. According to the distance, all effect factors were classified into different clusters by system clustering, and the relationship between effect factors and mental health was further analyzed. Results Combining the results of the three algorithms, we found that social support and personality traits factors had a certain rule on the effect of college students' psychological health, and social support factors were more important than personality traits factors. Among the social support factors, the most important was family support, followed by friend support and other support. The higher the level of support of the three, the greater the possibility of psychological health. In the personality traits factors, the most important was N, followed by E, and P. The three grades were high or low, may lead to abnormal psychology, and the medium grade was an important condition to maintain psychological health. Conclusion The results provided important references for the analysis of the effect factors on psychological health and important theoretical basis for the formulation of psychological intervention measures for college students.
Relationship of Supplement Intake Behavior to Performance and Grazing Behavior of Cattle Grazing Mixed-Grass Rangelands

This study evaluated the relationships between supplement intake behavior, beef cattle performance, and grazing behavior on dormant northern mixed-grass rangelands. In each of two years, a commercial herd of bred cows grazed a rangeland pasture from November to January. All cattle were managed as one contemporary group. Calf birth date, birth weight, and adjusted 205-day weaning weight were collected for each cow following the grazing season each year as cow performance metrics. During the grazing season, all cattle were provided free-choice access to a self-fed supplement. Supplement intake behavior was measured for each individual. Grazing behavior was monitored for 30 randomly selected individuals. The relationship of individual average daily supplement intake (R = 0.65; ρ = 0.65), supplement consumption rate (R = 0.58; ρ = 0.54), the coefficient of variation of supplement intake (R = 0.51; ρ = 0.50), and the amount of time spent at the feeder (R = 0.47; ρ = 0.49) were positively correlated and ranked across years (P < 0.01), suggesting individual animal supplement intake behavior is repeatable for cattle grazing dormant season rangelands. Additionally, there were multiple significant associations between supplement intake behavior, cattle performance, and grazing behavior (P ≤ 0.05); however, the majority were weak associations that accounted for minimal variation in cattle performance and grazing behavior (R ≤ 0.27; r ≤ 0.07). Although supplement intake behavioral traits were repeatable across years, its use as a metric to predict animal performance and grazing behavior may be limited.
Retirees from public service: the journey to small enterprise ownership

ABSTRACT This paper explores entrepreneurial activities and experiences. We do this to develop an understanding of the experiences and needs of a specific subgroup of entrepreneurs. We present insights from the silver economy based on the experiences of nine entrepreneurs who became entrepreneurs retiring from the public service. Data were collected in extended face-to-face interviews. The findings represent a detailed biography of each entrepreneur. The emergence of the silver economy provides opportunities for small enterprise development. The retirees who participated in this study are particularly well placed to pursue an entrepreneurial journey. They have key advantages in terms of access to resources and expertise, which are vital to entrepreneurship. In addition, they have both the capacity and the desire to continue working. We conclude that there is a need for tailored information; designated contact points; customized training and provisions in the revenue and welfare system to negate any impacts on pensions and other entitlements.
Hysteresis modeling of impact dynamics using artificial neural network

In this paper, the process of training an artificial neural network (ANN) on predicting the hysteresis of a viscoelastic ball and ash wood bat colliding system is discussed. To study how the material properties and the impact speed affect the hysteresis phenomenon, many experiments were conducted for colliding three types of viscoelastic balls known as sliotars at two different speeds. The aim of the study is to innovate a neural network model to predict the hysteresis phenomenon of the collision of viscoelastic materials. The model accurately captured the input data and was able to produce data sets out of the input ranges. The results show that the ANN model predicted the impact hysteresis accurately with <1% error.
Student Perception of Traditional English Teaching Methods (CLT approach) and Comparison to Modern Methods (Using Technology)

This study aimed to assess the perception of students regarding traditionally used CLT approach for teaching English language and its comparison to modern teaching methods based on technology. Survey was carried out using a quantitative analysis on 200 students of English language teaching institutes that are currently using CLT approach. Pre and post responses survey was carried out wherein their perspectives were assessed before and after exposure to technology-based ELT methods. Analysis was carried out using Wilcoxin test which revealed the impact of modern technological tools used in language teaching, such as, video conferencing, audio CDs, online oral versions, text-to-speech synthesis, interactive books, digital game-based learning and computer assisted language learning (CALL).
Usefulness of Early Diagnosis of Sepsis-Induced Coagulopathy by Measuring Novel Platelet Activation Marker Soluble Type C Lectin-Like Receptor 2 (CLEC-2)

Background: C-type lectin-like receptor 2 (CLEC-2) is a platelet-activated receptor expressed on the surface of platelet membranes. Soluble CLEC-2 (sCLEC-2) has been receiving attention as a predictive marker for thrombotic predisposition, such as cerebral or myocardial infarction. In the present study, we examined the relationship between sCLEC-2 level and degree of coagulation disorder, especially platelet activation, in sepsis patients. Methods: Seventy sepsis patients were enrolled and divided into two groups, sepsis-induced disseminated intravascular coagulation (DIC) (SID) group (n=44) and non-SID group (n=26), at the time of intensive care unit admission. In addition, 37 healthy adult volunteers were enrolled as a control group. The sCLEC-2 levels were measured and compared among the groups. Because we suspected that the sCLEC-2 level was likely to be affected by the platelet count, we also calculated the sCLEC-2/platelet count ratio (termed C2PAC index) in the groups. We further divided the sepsis patients into four groups using the Japanese Acute Medical Association (JAAM) DIC scoring system (DIC scores: 0–1, 2–3, 4–5, 6–8) and investigated the C2PAC indexes in the healthy volunteers and the four JAAM DIC score groups. Finally, we examined whether the C2PAC index could be a predictor of DIC by receiver-operating curve (ROC) analysis.Results: The C2PAC indexes in the healthy volunteers, non-SID group, and SID group were 0.34±0.14, 1.2±0.5, and 2.6±1.7, respectively. The index was significantly higher in the non-SID and SID groups compared with the healthy volunteers and also significantly higher in the SID group compared with the non-SID group (all P<0.001). The C2PAC indexes in the healthy volunteers and the four JAAM DIC score groups were 0.3±0.1, 0.9±0.3, 1.1±0.3, 1.7±0.7, and 3.6±1.0, respectively. Furthermore, the C2PAC index increased significantly as the DIC score increased (P<0.001). According to the ROC analysis, the area under the curve and optimal cut-off value for the diagnosis of DIC were 0.80507 and 1.40 (sensitivity, 75.0%; specificity, 76.9%), respectively.Conclusions: The present findings suggest that evaluation of the C2PAC index may be a useful early predictor of sepsis-induced coagulopathy progression and DIC diagnosis in sepsis patients.Trial registration: This study was approved by the institutional ethics committees at Fukuoka University Hospital (U19-01-001), Yamanashi University Hospital (2289), and LSI Medience Corporation (Shindan/Narita 19-04).
Association Between Promoter Polymorphisms of IL-1B, IL-4 and IL-6 Genes and a Viral Load Infected Women with Human Papillomavirus

Background: The purpose of this study was to investigate the association between IL-4 -589C>T, IL-6 -174G>C, IL-1β -31T>C and IL-1β -511C>T genes polymorphism with high concentrations of human papillomavirus (HPV), and the influence of gene-gene interactions on persistent human papillomavirus infection. Methods: In this study, 101 infected women with high HPV viral load and 93 healthy women were involved in a case-control study. Genotyping of SNPs for IL-4 -589C>T, IL-6 -174G>C, IL-1β -31T>C and IL-1β -511C>T genes was carried out by allele-specific PCR. Quantitative analysis of HPV-DNA was performed by Amplisens HPV HCR genotype-titer software. Gene-gene interactions were analyzed using multifactor dimensionality reduction (MDR) algorithm. Haplotype interactions were analyzed by HaploView 4.2 tool. Results: The study of single individual SNPs in promoters of IL-4 -589C>T, IL-6 -174G>C and IL-1β -31T>C genes did not reveal statistically significant difference in genotypes and allele frequencies among women with high HPV viral load and control group. The frequency of -511T allele and TT genotype of the IL-1β gene in case group was significantly higher than the one in control group (OR=1.71, p=0.012 and OR=2.02, p=0.046, respectively). Haplotype analysis revealed that -511C/-31T haplotype for IL-1β gene is significantly less common among women with high HPV viral load (p=0.018). Conclusion: The haplotype -511C/-31T for IL-1β gene is associated with a protective effect against increasing HPV viral load. The frequencies of -511T allele and -511TT genotype of the IL-1β -511C>T were significantly higher among women with HPV in comparison to control group.
Enhancing motivation and engagement within a PBIS framework

A motivating and engaging school environment has been associated with several positive student outcomes. Consequently, schools have an opportunity and responsibility to promote a culture that supports students in developing and maintaining their motivation, engagement, and self-improvement. Efforts to promote such a culture can be embedded within a Positive Behavioral Interventions and Supports (PBIS) framework. In this paper, we begin by describing motivation and engagement, and discussing the relevance of these concepts in schools. Next, we introduce the traditional PBIS framework, highlighting research and core features. Third, we propose how PBIS can be enhanced by incorporating a focus on relationships, engagement, and motivation in the school setting. Finally, we conclude with recommendations for school teams seeking to implement this approach.
Evaluation of a silica hydride-based undecynoic acid stationary phase for high performance liquid chromatography

EVALUATION OF A SILICA HYDRIDE-BASED UNDECYNOIC ACID STATIONARY PHASE FOR HIGH PERFORMANCE LIQUID CHROMATOGRAPHY by Veena Menon Kozhikote Undecynoic acid (UDA) attached to a silica hydride surface has been found to exhibit weak cationic exchange properties and an aqueous normal phase (ANP) type of retention. ANP is a mechanism similar to normal phase chromatographic retention, except for the use of a polar solvent such as water in the mobile phase. In ANP, the retention of a polar molecule is increased with a higher concentration of the non-polar mobile phase solvent (usually acetonitrile). Non-polar molecules exhibit retention behavior as in reverse phase (RP) chromatography. The goal of this research was to characterize the chromatographic retention pattern of an undecynoic based silica hydride column by studying various polar and nonpolar analytes. Also investigated were the effects of varying the buffer concentrations -formic acid and ammonium acetate and the effect of temperature on the retention of selected compounds. It has been established from the current work that a silica hydride based UDA column can be used for separation and analysis of nucleotides and nucleosides as well as phenolic acid components in pomegranate peel samples. A phenyl hydride column was additionally used to complete the study on the peel samples since the UDA column was not effective in separating isobaric compounds found in the peels. In conclusion, silica hydride based UDA column has been found to exhibit dual retention capabilities for polar and non-polar molecules.
TERRESTRIAL LASER SCANNER FOR METRIC EXTRACTION IN EUCALYPTUS UNDER DIFFERENT IMPLANTATION SYSTEMS

This study evaluates the influence of the cropping system in the extraction of Eucalyptus benthamii metrics by terrestrial laser scanner (TLS) and by traditional inventory. The hypothesis is that the extraction methods do not differ significantly from each other. The study area consists of a conventional planting system under 3 x 2 m spacing, and a CFI (crop-forest integration) system under 14 x 2 m spacing. To obtain the variables DBH (diameter at 1.3 m aboveground) and total height (H), we used a traditional inventory and collected data with TLS. For point cloud processing, we manually extracted the metrics DBH and H by simple scanning. We estimated total volume (V) by a fitted equation that matches the characteristics of the study area. To estimate above-ground biomass (AGB), we fitted models based on AGB data provided by the NITA project and by BIOFIX. Better visualization of trees in the CFI system facilitated metric extraction, leading to less data variability. In addition, DBH, V, and AGB values were higher in the CFI system compared to the conventional system. However, when including the number of trees per hectare, the conventional system is more productive. The initial hypothesis was confirmed. Therefore, metric extraction using the traditional inventory and TLS methods did not differ significantly for the two cropping systems considered.
First-principles prediction of ideal type-II Weyl phonons in wurtzite ZnSe

Weyl materials, exhibiting topologically nontrivial touching points in band dispersion, are fascinating subjects of research, which have been extensively studied in electron-related systems. In this paper, by employing first-principles calculations of topological phonons in wurtzite-structured phases of $MX$ chalcogenides (where $M=\mathrm{Zn}$ and Cd and $X=\mathrm{O}$, S, Se, and Te), we demonstrate the existence of ideal type-II Weyl phonons in wurtzite ZnSe, a well-known II-VI semiconductor. There are in the ${\mathbf{q}}_{z}=0.0$ plane six pairs of Weyl points stemming from the inversion between the two optical branches. The nontrivial phonon surface states and surface arcs projected on the semifinite (0001) surfaces are investigated. Phonon surface arcs connecting each pair of Weyl points with opposite chirality, guaranteed to be $0.55\phantom{\rule{0.28em}{0ex}}{\AA{}}^{\ensuremath{-}1}$ and very long, are readily observable in experiment. The opposite chirality of Weyl points with quantized Berry curvature produces the Weyl phonon Hall effect. Our results propose a potential platform for future experimental study of type-II Weyl phonons in realistic materials.
Nanoscale selective area atomic layer deposition of TiO2 using e-beam patterned polymers

Here, we report nano-patterning of TiO2 via area selective atomic layer deposition (AS-ALD) using an e-beam patterned growth inhibition polymer. Poly(methylmethacrylate) (PMMA), polyvinylpyrrolidone (PVP), and octafluorocyclobutane (C4F8) were the polymeric materials studied where PMMA and PVP were deposited using spin coating and C4F8 was grown using inductively coupled plasma (ICP) polymerization. TiO2 was grown at 150 °C using tetrakis(dimethylamido) titanium (TDMAT) and H2O as titanium and oxygen precursors, respectively. Contact angle, scanning electron microscopy (SEM), spectroscopic ellipsometry, and X-ray photoelectron spectroscopy (XPS) measurements were performed to investigate the blocking/inhibition effectiveness of polymer layers for AS-ALD of TiO2. TiO2 was grown with different numbers of growth cycles (maximum = 1200 cycles) on PMMA, PVP, and C4F8 coated substrates, where PMMA revealed complete growth inhibition up to the maximum number of growth cycles. On the other hand, PVP was able to block TiO2 growth up to 300 growth cycles only, whereas C4F8 showed no TiO2-growth blocking capability. Finally, mm-, μm-, and nm-scale patterned selective deposition of TiO2 was demonstrated exploiting a PMMA masking layer that has been patterned using e-beam lithography. SEM, energy-dispersive X-ray spectroscopy (EDX) line scan, EDX elemental mapping, and XPS line scan measurements cumulatively confirmed the self-aligned deposition of TiO2 features. The results presented for the first time demonstrate the feasibility of achieving self-aligned TiO2 deposition via TDMAT/H2O precursor combination and e-beam patterned PMMA blocking layers with a complete inhibition for >50 nm-thick films.
FORMULATION AND EVALUATION OF IN-SITU NASAL GEL OF RIZATRIPTAN BENZOATE BY USING MUCOADHESIVE POLYMERS

Rizatriptan Benzoate undergo hepatic first pass metabolism. Aim of present research work is to improve bioavailability by formulating in-situ nasal gel. Formulation was developed to decrease the mucociliary authorization by using mucoadhesive polymer in gel, thus rising the contact time with nasal mucosa and humanizing the absorption of drug. Gels were primed by cold technique process and evaluate by Appearance, Viscosity, Gelation Temperature, Permeation Studies, Drug Content, Gel strength etc. The gelation temperature of all studied gel formulations were found in range. Drug release was initiated in between 68.8-94.7% with K-peppas best fit model. pH of gel was in the rang and drug content was found between 92-99.89 %. Gel strength was found in range of 20-55 sec. Keyword s: Rizatriptan Benzoate, Mucociliary, Strength
Variable Stiffness Mechanism for the Reduction of Cutting Forces in Robotic Deburring

One of the main issues related to robotic deburring is that the tool can get damaged or stopped when the burr thickness exceeds a certain threshold. The aim of this work is to devise a mechanism that can reduce cutting forces automatically, in the event that the burr is too high, and is able to return to the baseline configuration when the burr thickness is acceptable again. On the one hand, in normal cutting conditions, the mechanism should have high stiffness to ensure high cutting precision. On the other hand, when the burr is too high the mechanism should exploit its compliance to reduce the cutting forces and, as a consequence, a second cutting cycle will be necessary to completely remove the burr. After the conceptual design of the mechanism and the specification of the desired stiffness curve, the main design parameters of the system are derived thanks to an optimization method. The effectiveness of the proposed mechanism is verified by means of dynamic simulations using selected test cases. A reduction up to 60% of the cutting forces is obtained, considering a steel burr up to 6 mm high.
Low-Energy Mass-Selected Ion Beam Production of Fragments Produced from Hexamethyldisilane for SiC Film Formation

We have proposed an experimental methodology which makes it possible to deposit silicon carbide (SiC) films on Si substrates with a low-energy mass-selected ion beam system using hexamethyldisilane (HMD) as a gas source. In this study, one of the fragment ions produced from HMD, SiCH4+, was mass-selected. The ion energy was approximately 100 eV. Then, the SiCH4+ ions were irradiated to a Si(100) substrate. When the temperature of the Si substrate was set at 800 °C during the ion irradiation, the X-ray diffraction and Raman spectroscopy of the substrate following the completion of ion irradiation experiment demonstrated the occurrence of 3C-SiC deposition.
Current Progress in Cancer Immunotherapies Using Small Molecules Targeting PD-L1 Stability

PD-L1 is an immune checkpoint protein that is frequently overexpressed by the cells in the tumor microenvironment. PD-L1 binds to PD-1 present on the activated antitumor T-cells, which allows for tumor immune escape. The ability of the PD-1/PD-L1 axis to suppress antitumor immunity enables its application as a potential target for small-molecule-based immunotherapies. Targeting the PD-L1-mediated tumor immune evasion represents a promising approach for immune checkpoint blockade therapies. However, the existing monoclonal antibody-based therapies present poor overall response rates, warranting the development of small molecule drugs with the ability to regulate PD-L1 stability and enhance antitumor immunity. In this context, the present review summarizes the mechanisms of upstream PD-L1 regulation by kinases, cell cycle modulators, ubiquitin ligases, and glycosylation modulators, as well as the efficacy of small molecules targeting PD-L1 stability in regulating PD-L1-mediated immune evasion.