Miracle-dz/UniFAR-FTUs huggingface dataset:
I.v. tenoxicam for analgesia during caesarean section.

We have studied the analgesic efficacy of a single i.v. dose of tenoxicam 20 mg, given 10 min before induction of anaesthesia in 25 patients undergoing elective Caesarean section. Another group of 25 similar patients served as controls. Nalbuphine consumption in the first 24 h after operation was reduced by 50% when tenoxicam was given. The median time to first request for analgesia was increased from 25 to 110 min in the tenoxicam group. Subjective experiences of pain and sedation were significantly greater in the control group up to 24 h after operation. The haemodynamic variability after intubation was of shorter duration in the tenoxicam group. There was no significant difference in incidence and severity of postoperative nausea and vomiting between the two groups. The surgeon's assessment of uterine relaxation and bleeding, using a visual analogue score, and infant well-being, as judged by Apgar score and cord blood-gas analysis, showed no significant difference between the two groups. There was no evidence of premature closure of the ductus arteriosus or pulmonary hypertension. We conclude that a single i.v. dose of tenoxicam is a useful pretreatment to minimize the haemodynamic variability of light general anaesthesia at induction-delivery and in reducing 24 h postoperative opioid consumption.
Shed L-selectin (sCD62L) load in trauma patients.

BACKGROUND Low circulating plasma concentrations of the leukocyte adhesion molecule L-selectin (sCD62L) were found to be associated with an increased risk for subsequent lung failure and case fatality after severe trauma. The objective of this study was to determine the robustness of soluble L-selectin, correcting for a broad spectrum of physiological variables. METHODS Patients with suspected multiple and/or trunk injuries were enrolled into this study over a 1-year period. Plasma samples were obtained on hospital presentation, and circulating soluble L-selectin was measured with a commercially available ELISA kit. Study records comprised all relevant clinical and laboratory data. Thirty-day survival rate, subsequent acute lung failure, and nosocomial pneumonia were defined as study endpoints. Statistical analysis was performed using multivariate logistic regression models. RESULTS Seventy patients with a mean age of 35.51 years (range, 10-87 years) and a mean ISS score of 36.61 (95% CI, 31.08-42.14) entered the study. Eleven patients died, leading to an attributable mortality of 15.70%. L-Selectin levels did not differ between survivors and nonsurvivors. Five patients progressed to acute lung injury, whereas 11 patients developed hospital-acquired pneumonia. Lower L-selectin levels indicated patients at risk for lung injury with a relative odds estimated at 4.43 (P = 0.017). Statistical significance diminished in the multivariate model. In contrast, plasma concentrations of circulating sCD62L were significantly decreased in patients developing nosocomial pneumonia (P = 0.023), with a twofold increased relative odds (OR, 1.96; 95% CI, 0.51-7.50). No effect modification was observed by the included covariables. CONCLUSIONS The results of this study highlight the independent predictive value of initially decreased soluble L-selectin levels for the identification of patients susceptible to subsequent respiratory complications after severe trauma.
Calcium and cyclic nucleotide interaction in secretion of amylase from rat pancreas in vitro.

1. Interaction of Ca2+ and cyclic nucleotides in stimulus‐secretion coupling in rat pancreas in vitro was studied utilizing the divalent cation inophore A23187. phosphodiesterase inhibitors, cyclic nucleotides and cholera toxin. 2. Amylase secretion was increased by the ionophore in the presence of extracellular Ca2+ in a dose‐dependent fashion. Activation of CCK‐PZ receptors simultaneously with induction of amylase secretion by A23187 did not alter amylase secretion whereas theophylline or caffeine had effects additive to A23187. Dibutyryl cyclic AMP potentiated the effect of ionophore whereas dibutyryl cyclic GMP had no effect on basal or ionophore‐induced amylase secretion. Cholera toxin by itself did not effect amylase secretion whereas it potentiated the effect of ionophore. 3. A23187 increased bidirectional fluxes of 45Ca and increased efflux of 45Ca in a fashion similar to CCK‐PZ. Theophylline did not alter basal efflux of 45Ca. Dibutyryl cyclic AMP increased the basal efflux of 45Ca whereas, cholera toxin, dibutyryl cyclic GMP and sodium butyrate had no effect. 4. Theophylline increased basal cyclic AMP levels with a peak effect observed at 5 min. Combination of theophylline and ionophore did not lead to an increase in levels of cyclic AMP greater than that observed with theophylline alone. Cholera toxin increased cyclic AMP levels at 30 and 60 min of incubation. 5. Ionophore and CCK‐PZ increased tissue cyclic GMP levels significantly greater than that obtained with theophylline alone. This effect was dependent on extracellular Ca2+. The effect of ionophore on tissue levels of cyclic GMP could be dissociated from its effect on 45Ca efflux and amylase secretion. 6. It is concluded from these studies that Ca2+ plays a predominant role in regulating amylase secretion with interactions occurring between Ca2+ and cyclic AMP and Ca2+ and cyclic GMP. It appears that by themselves cyclic AMP and cyclic GMP do not play a significant role in regulating enzyme secretion.
Isomerism in the setting of the so-called “heterotaxy”: The usefulness of computed tomographic analysis

The most complex combinations of congenital cardiac malformations are found in the setting of bodily isomerism. The question remains, however, as to whether evidence of cardiac isomerism is always to be found in the setting of bodily isomerism, also known as “heterotaxy. ” We have previously shown that, when assessed on the basis of the extent of the pectinate muscles relative to the atrioventricular junctions, there is always isomerism of the atrial appendages in this setting. Doubt has been remained, however, as to whether these cardiac features can accurately be recognized during life. We have now encountered two patients showing features of the left and right bodily isomerism. Examinations of these patients made using computed tomography show that all features of isomerism, no matter how complex, can now be visualized during life. The images currently presented show, furthermore, that the features of the so-called “heterotaxy” can be seen during life, not only within the heart but also in all the thoracic and abdominal organs, albeit that the isomeric features are confined to the thoracic organs. Based on the images presented, we argue that if each system of organs is analyzed and described in independent fashion; then it is possible for clinicians to exclude any suggestion of ambiguity and to provide accurate descriptions of the overall arrangement. We further discuss the appropriate terminology to describe the entity we prefer to call isomerism, along with the indications and usefulness of computed tomography in revealing the anatomic features of the congenitally malformed heart.
A One-way Active Measurement Protocol (OWAMP)

The One-Way Active Measurement Protocol (OWAMP) measures unidirectional characteristics such as one-way delay and one-way loss. High-precision measurement of these one-way IP performance metrics became possible with wider availability of good time sources (such as GPS and CDMA). OWAMP enables the interoperability of these measurements. [STANDARDS-TRACK]
ROBUSTNESS OF WILKS' CONSERVATIVE ESTIMATE OF CONFIDENCE INTERVALS

The striking generality and simplicity of Wilks’ method has made it popular for quantifying modeling uncertainty. A conservative estimate of the confidence interval is obtained from a very limited set of randomly drawn model sample values, with probability set by the assigned so-called stability. In contrast, the reproducibility of the estimated limits, or robustness, is beyond our control as it is strongly dependent on the probability distribution of model results. The inherent combination of random sampling and faithful estimation in Wilks’ approach is here shown to often result in poor robustness. The estimated confidence interval is consequently not a well-defined measure of modeling uncertainty. To remedy this deficiency, adjustments of Wilks’ approach as well as alternative novel, effective but less known approaches based on deterministic sampling are suggested. For illustration, the robustness of Wilks’ estimate for uniform and normal model distributions are compared.
Novel Design of Surface-Wave Holographic Antenna Miniaturization

This letter proposed a novel miniaturization technique for surface-wave holographic antenna, which determines the layout of the antenna by simply cutting out the region where the scattering is inefficient from the original interference pattern. Then, the equivalent method of physical truncation and perfect magnetic conductor truncation is presented and theoretically analyzed to increase the gain and eliminate the zeroth-order. For the design example radiated at 30° off the normal, it is shown that the area of the miniaturized is 82.4% smaller and the gain is 3.61 dB in measurement higher than that of the original antenna, respectively.
PATTERN RECOGNITION APPROACHES FOR SPEECH-TO-SPEECH TRANSLATION

We propose a statistical approach to speech-to-speech translation that uses finite-state models in all levels. Acoustic hidden Markov models (HMMs) model the pronunciation of the input-language phonemes and words, while the input–output word mapping, along with the syntax of the output language, are jointly modeled by means a large stochastic finite-state transducer. This allows for a complete integration of all the models so that the translation process can be performed by searching for an optimal path of states through the integrated network. As in speech recognition, HMMs can be trained from an input-language speech corpus, and the translation model is learned automatically from a parallel (text) training corpus. This approach has been assessed in the framework of the EuTrans project, funded by the European Union. Extensive experiments have been carried out with speech-input translations from Spanish to English and from Italian to English in applications involving the interaction (by telephone) of a customer with the front desk of a hotel. A summary of the most relevant results is presented.
Analysis of TP 53 gene expression and p 53 level of human hypopharyngeal FaDu ( HTB-43 ) head and neck cancer cell line after microRNA-181 a inhibition

The identification of new biomarkers for early detection of highly recurrent head and neck cancer is urgently needed. MicroRNAs (miRNAs) are small and non-coding RNAs that regulate cancer-related gene expression, such as tumor protein 53 (TP53) gene expression. This study was carried out to analyze TP53 gene expression using real-time PCR and to determine changes in intracellular p53 level by flow cytometry after downregulation of miRNA-181a miRNA inhibitor in the FaDu cell line. TP53 gene expression showed a 3-fold increment and the p53 protein level was also increased in the miRNA-181a-treated cells. In conclusion, 1680 Y.K. Cheah et al. ©FUNPEC-RP www.funpecrp. com.br Genetics and Molecular Research 13 (1): 1679-1683 (2014) miRNA-181a binds to the TP53 gene and inhibits its expression, decreasing the synthesis of p53.
Underestimation of left atrial size measured with transthoracic echocardiography compared with 3D MDCT.

OBJECTIVE High-resolution 64-MDCT images of the beating heart can be used for measurement of left atrial volume with 3D chamber reconstruction. The purpose of this study was to correlate measurements of left atrial volume obtained with clinical transthoracic echocardiography (TTE) and measurements obtained with 64-MDCT 3D reconstructions of the left atrium. MATERIALS AND METHODS Patients who underwent TTE and MDCT within 3 days were identified. TTE images were graded as excellent, good, or suboptimal. Two independent observers calculated estimates of left atrial volume from TTE and 64-MDCT images using 3D chamber reconstructions and conventional geometric assumptions on MDCT echocardiographic views. RESULTS MDCT estimates of phantom volume on 3D chamber reconstructions agreed with actual volumes within 1.5%. The TTE images of 37 of the 52 patients were judged to be of good or excellent quality and were included in the analysis. Mean left atrial volume measured on 3D chamber reconstructions was 61 +/- 14 mL/m(2). Estimates of left atrial volume obtained with TTE were significantly lower (28 +/- 12 mL/m(2)) than similar estimates obtained with MDCT echocardiographic views (53 +/- 15 mL/m(2)) (p < 0.001). TTE left atrial volume and 3D chamber reconstruction left atrial volume exhibited moderate correlation (r = 0.60-0.70), but the correlation improved when analysis was limited to the 26 studies with excellent-quality TTE images (r = 0.71). MDCT echocardiographic estimates of left atrial volume with the area-length method had excellent correlation (r = 0.89) with and were closest to estimates made on 3D chamber reconstructions. CONCLUSION Left atrial volume is significantly underestimated on TTE images, and TTE estimates have moderate correlation with left atrial volume measured with MDCT. Measured and estimated left atrial volumes at MDCT can provide important additive prognostic information in the care of patients undergoing MDCT for other reasons. Future studies are needed to obtain normative MDCT measurements of left atrial volume.
What is cognitive linguistics? A new framework for the study of Basque

What is cognitive linguistics? A new framework for the study of Basque Iraide Ibarretxe Antuñano Introduction: More than one Cognitive Linguistics? Cognitive Linguistics is a new approach to the study of language which views linguistic knowledge as part of general cognition and thinking; linguistic behaviour is not separated from other general cognitive abilities which allow mental processes of reasoning, memory, attention or learning, but understood as an integral part of it. It emerged in the late seventies and early eighties, especially through the work of George Lakoff, one of the founders of Generative Semantics, and Ronald Langacker, also an ex-practitioner of Generative Linguistics. As a consequence, this new paradigm could be seen as a reaction against the dominant generative paradigm which pursues an autonomous view of language (see Ruiz de Mendoza, 1997). Some of the main assumptions underlying the generative approaches to syntax and semantics are not in accordance with the experimental data in linguistics, psychology and other fields; the „generative commitment‟ to notational formalism, that is to say the use of „formal grammars‟ which view languages as systems of arbitrary symbols manipulated by mathematical rules of the sort first characterised by Emil Post, is employed at the expense of descriptive adequacy and psychological realism (see Lakoff, 1987). What Lakoff (1990: 43) refers to as „non-finitary phenomena‟, i.e. mental images, general cognitive processes, basiclevel categories, prototype phenomena, the use of neural foundations for linguistic theory and so on, are not considered part of these grammars because they are not characterisable in this notation. It is from this dissatisfaction with the dominant model that Cognitive Linguistics was created. Although Cognitive Linguistics as a general framework emerged in the late seventies, it is important to bear in mind two points. Firstly, some of the cognitive assumptions central to this approach are not new. Authors such as Geeraerts (1988), Jäkel (1999), Nerlich and Clarke (2001a, b, 2002) and Taylor (1995) have shown that many of the ideas that I will
Algorithm to prevent back end database against SQL injection attacks

SQL injection attack (SQLIA) is a technique through which attackers gain access over back-end databases by inserting the malicious codes through front-end. In recent times SQL injection attacks (SQLIAs) have emerged as a major threat to database security. Flaws in designing, improper coding practices, configuration errors, improper validation of user input etc. makes the web application vulnerable and allows the malicious user to obtain unrestricted access to confidential information. Researchers have proposed so many solutions but still SQLIAs exist. In this paper we will discuss several types of SQLIAs, existing techniques and their drawbacks. Finally I have proposed a solution using the ASCII values. I have implemented it using C# and SQL server 2005, although this algorithm can be implemented in any language and for any database platform with minimal modifications.
Gender and Ethnic Differences in Cancer Pain Experience: A Multiethnic Survey in the United States

Background: Inconsistent findings on ethnic differences in cancer pain experience suggest the need for further studies on this topic for adequate cancer pain management. Objectives: To determine ethnic differences in cancer pain experience of four ethnic groups in the United States. Methods: A feminist perspective was used as the theoretical basis. This was a survey of a multiethnic sample of 480 cancer patients asking questions on sociodemographic characteristics and health or illness status, 3 unidimensional cancer pain scales, 2 multidimensional cancer pain scales, the Memorial Symptom Assessment Scale, and the Functional Assessment of Cancer Therapy Scale. The data were analyzed using descriptive and inferential statistics including ANOVA and hierarchical multiple regression analyses. Results: The results indicated certain ethnic differences in types of pain and symptoms that patients experienced. Also, the results demonstrated significant ethnic differences in cancer pain and functional status. Discussion: The findings suggest further in-depth qualitative exploration on cultural values and beliefs related to cancer pain in each ethnic group and national studies with a larger number of ethnic minorities on this topic.
Lipopolysaccharide Stimulates the Proliferation of Human CD56+CD3− NK Cells: A Regulatory Role of Monocytes and IL-101

NK cells recognize and kill tumor cells and normal cells, and these play an important role in immune defense in cancer, infectious disease, and autoimmunity. NK killing is regulated by positive or negative signals derived from the interaction of surface receptors with ligands on the target cells. However, the mechanisms controlling the proliferation and maintenance of NK cells in normal human individuals are less clearly defined. In this study, using an entirely autologous system, we demonstrate that human peripheral blood CD3−CD56+, killer cell-inhibitory receptor (KIR)-expressing cells proliferate and expand in response to LPS. These responses are enhanced in the presence of anti-IL-10 receptor-blocking Abs or on the removal of CD14+ cells from the cultures. This enhancement is also reflected in substantial increases in cytolytic activity and IFN-γ production. The negative effect of CD14+ cells may also be IL-10 mediated, IL-10 being lost from the culture supernatants of CD14-depleted PBMC and rIL-10 reversing the effect of this depletion. On the other hand, mRNA for the p35 and p40 subunits of IL-12 is still induced in CD14-depleted cultures. The expansion of CD3−CD56+ cells was also inhibited by CTLA4-Ig, indicating a role for CD80/86. B lymphocytes were not required for the expansion of CD3−CD56+ cells, whereas removal of MHC class II+ cells from CD14-depleted cultures resulted in a complete abrogation of these responses. Expansion of CD3−CD56+ cells was reconstituted in MHC class II-depleted cell cultures by adding back monocyte-derived dendritic cells. These results indicate that the responses of CD3−CD56+ NK cells to LPS may be driven by a MHC class II+ B7+ CD14− peripheral population, most likely blood dendritic cells.
A Volterra series approach for the design of low-voltage CG-CS active baluns

A low-voltage active balun and amplifier is presented. The circuit uses a common-gate common-source (CG-CS) noise-cancelling topology with a simple distortion cancellation method to improve the IIP3 performance of the balun-amplifier. A Volterra series analysis is employed to provide insights into the nonlinear behavior of the circuit. A chip was fabricated and the experimental test results show an average voltage gain for the balun-amplifier of 16.2 dB and a maximum IIP3 of -3.8 dBm over the span of 0.3-2.4 GHz. The circuit exhibits a noise figure below 4.0 dB over the measured band and reaches a minimum of 3.2 dB. The chip uses a single 0.9 V dc supply and consumes 15.8 mW of power. The RFIC was fabricated using a standard 130 nm CMOS process.
NopP, a phosphorylated effector of Rhizobium sp. strain NGR234, is a major determinant of nodulation of the tropical legumes Flemingia congesta and Tephrosia vogelii

Rhizobium sp. NGR234 nodulates many plants, some of which react to proteins secreted via a type three secretion system (T3SS) in a positive‐ (Flemingia congesta, Tephrosia vogelii) or negative‐ (Crotalaria juncea, Pachyrhizus tuberosus) manner. T3SSs are devices that Gram‐negative bacteria use to inject effector proteins into the cytoplasm of eukaryotic cells. The only two rhizobial T3SS effector proteins characterized to date are NopL and NopP of NGR234. NopL can be phosphorylated by plant kinases and we show this to be true for NopP as well. Mutation of nopP leads to a dramatic reduction in nodule numbers on F. congesta and T. vogelii. Concomitant mutation of nopL and nopP further diminishes nodulation capacity to levels that, on T. vogelii, are lower than those produced by the T3SS null mutant NGRΩrhcN. We also show that the T3SS of NGR234 secretes at least one additional effector, which remains to be identified. In other words, NGR234 secretes a cocktail of effectors, some of which have positive effects on nodulation of certain plants while others are perceived negatively and block nodulation. NopL and NopP are two components of this mix that extend the ability of NGR234 to nodulate certain legumes.
Evaluation of SiGeC HBT Varactor using different Collector access and Base-Collector junction Configuration in BiCMOS technologies

This paper is focused on the evaluation of SiGeC HBT varactor in BiCMOS technologies. First, we compare a standard collector-base junction varactor with the contribution of specific collector between a low cost SiGeC HBT module. From this, we suggest new types of structure with no additional mask which allows to keep high quality factor and to have a wide tuning range (3:1) between standard diode P+/Nwell and HBT varactor with SIC implant.
Properties of Desulfovibrio carbinolicus sp. nov. and Other Sulfate-Reducing Bacteria Isolated from an Anaerobic-Purification Plant

Several sulfate-reducing microorganisms were isolated from an anaerobic-purification plant. Four strains were classified as Desulfovibrio desulfuricans, Desulfovibrio sapovorans, Desulfobulbus propionicus, and Desulfovibrio sp. The D. sapovorans strain contained poly-β-hydroxybutyrate granules and seemed to form extracellular vesicles. A fifth isolate, Desulfovibrio sp. strain EDK82, was a gram-negative, non-spore-forming, nonmotile, curved organism. It was able to oxidize several substrates, including methanol. Sulfate, sulfite, thiosulfate, and sulfur were utilized as electron acceptors. Pyruvate, fumarate, malate, and glycerol could be fermented. Because strain EDK82 could not be ascribed to any of the existing species, a new species, Desulfovibrio carbinolicus, is proposed. The doubling times of the isolates were determined on several substrates. Molecular hydrogen, lactate, propionate, and ethanol yielded the shortest doubling times (3.0 to 6.3 h). Due to the presence of support material in an anaerobic filter system, these species were able to convert sulfate to sulfide very effectively at a hydraulic retention time as short as 0.5 h.