Miracle-dz/UniFAR-FTUs huggingface dataset:
O ( nitric oxide ) : The ring master waraj Sinhaa , Sree

The migration and proliferation of endothelial cells affect the process of angiogenesis or the formation of blood vessels. Endothelial cells interact with each other to form ring-like structures in monolayers and tubular structures in matrigels. However, the transit phase between the individual endothelial cells and fully formed tubular structures is yet to be established. Guided by imaging, Western blot analysis, drug perturbation studies and siRNA studies we validate that endothelial ring structures are the fundamental and monomeric units of capillary tubes and nitric oxide is implicated in their fabrication. Giving input from ndothelial cells itric oxide ngiogenesis ndothelial nitric oxide synthase yclic guanosine monophosphate oluble guanylate cyclase experimental data, we used bagging classifier and information-gain to determine some of the physical and chemical parameters that define these biological structures. Further, we elucidated the implications of endothelial nitric oxide synthase and the NO/sGC/cGMP pathway in the formation of endothelial rings. We conclude that, formation of endothelial ring structure is important for angiogenesis and is mediated by the NO/sGC/cGMP pathway; and further endothelial rings can be used as in vitro models to study angiogenesis. rotein kinase G asodilator-stimulated phosphoprotein
The search for faint radio supernova remnants in the outer Galaxy: five new discoveries

High resolution and sensitivity large-scale radio surveys of the Milky Way are critical in the discovery of very low surface brightness supernova remnants (SNRs), which may constitute a significant portion of the Galactic SNRs still unaccounted for (ostensibly the Missing SNR problem). The overall purpose here is to present the results of a systematic, deep data-mining of the Canadian Galactic Plane Survey (CGPS) for faint, extended non-thermal and polarized emission structures that are likely the shells of uncatalogued supernova remnants. We examine 5$\times$5 degree mosaics from the entire 1420 MHz continuum and polarization dataset of the CGPS after removing unresolved point sources and subsequently smoothing them. Newly revealed extended emission objects are compared to similarly-prepared CGPS 408 MHz continuum mosaics, as well as to source-removed mosaics from various existing radio surveys at 4.8 GHz, 2.7 GHz, and 327 MHz, to identify candidates with non-thermal emission characteristics. We integrate flux densities at each frequency to characterise the radio spectra behaviour of these candidates. We further look for mid- and high-frequency (1420 MHz, 4.8 GHz) ordered polarized emission from the limb brightened shell-like continuum features that the candidates sport. Finally, we use IR and optical maps to provide additional backing evidence. Here we present evidence that five new objects, identified as filling all or some of the criteria above, are strong candidates for new SNRs. These five are designated by their Galactic coordinate names G108.5+11.0, G128.5+2.6, G149.5+3.2, G150.8+3.8, and G160.1$-$1.1. These discoveries represent a significant increase in the number of SNRs known in the outer Galaxy second quadrant of longitude (90$^{\circ} \leq \ell \leq $180$^{\circ}$).
Tumorigenesis and Neoplastic Progression Matriptase Is Involved in ErbB-2-Induced Prostate Cancer Cell Invasion

Deregulation of both ErbB-2 signaling and matriptase activity has been associated with human prostate cancer (PCa) progression. In this communication, we investi-gated the roles of both ErbB-2 signaling in matriptase zymogen activation and matriptase in ErbB-2-induced PCa malignancy. In a human PCa cell progression model, we observed that advanced PCa C-81 LNCaP cells exhibited an aggressive phenotype with increased cell migration and invasion capacity; these cells concur-rently showed both enhanced ErbB-2 phosphorylation and increased matriptase zymogen activation compared with parental C-33 LNCaP cells. Moreover, ErbB2 activation, both ligand-dependent (eg, epidermal growth factor treatment) and ligand-independent (eg, overexpression), was able to induce matriptase zymogen activation in this cell line. Inhibition of ErbB-2 activity by either the specific inhibitor, AG825, in epidermal growth factor-treated C-33 LNCaP cells or ErbB-2 knockdown in C-81 LNCaP cells, reduced matriptase activation. These observations were confirmed by similar studies using both DU145 and activation, matriptase activation, and prostate cancer cell migration and invasiveness.
The Discrepancy of Students' Mathematic Achievement through Cooperative Learning Model, and the ability in mastering Languages and Science

This experimental research with factorial 3x3 design aims at: (1) finding out the senior high school students’ mathematic achievement through (i) the effect of math on students’ language (Indonesian, English) and Science achievement, (ii) the effect of cooperative learning methods, namely Jigsaw, STAD, TSTS with certain condition of language mastery level (Indonesian, English), (iii) the effect of Science and language mastery (Indonesian, English), (iv) the discrepancy type 1, 2, 3, 4 and math achievement on the condition of Science and language mastery (Indonesian, English). The analysis result under hypothesis testing shows that (i) Math subject has significant and positive effect on students’ language (Indonesian, English) and Science mastery; each contributes 0.098; 0.089; and 0.808 which indicates that math can enhance the mastery of language (Indonesian, English) and Science, (ii) cooperative learning method including Jigsaw TSTS, STAD has significant effect, (iii) the discrepancy type 1, 2, 3 do not have significant difference, and (iv) discrepancy type 4 has significant effect on students’ math achievement.
Seed bio-priming approach to amplify production potential of mungbean (Vigna radiata L.) in sandy soils

Seed treatment with living microorganisms is an eco-friendly and effective alternative to chemical seed treatment which improves plant growth and production. To evaluate this approach, three kinds of microbes exclusive and also in combinations were applied to the seeds of two mungbean genotypes and grown under field conditions during the summer season 2016. The bio-primed seeds significantly affected and promoted growth and yield related traits like emergence count (EC), leaf area index (LAI), chlorophyll content (Chl), number of nodules plant (NNP), number of pods plant (NPP), number of grains pod (NGP), thousand seed weight (TSW), biomass (BM) and grain yield (GY) . The genotype NM-11 under the combined treatment of microbes (MR-1/1 + MR-1/2 + SR-5-1) outperformed genotype NCM by producing higher grain yield 3460 kg ha, while untreated seeds observed the lowest grain yield 1969 kg ha. Bio-priming proved its supremacy over unprimed seeds by improving growth and yield related traits. Significant and positive correlations were also observed between growth and yield parameters under different treatments of microbes. These results suggest that seed bio-priming by combining different microbes can be used to augment mungbean crop outputs under sandy soils conditions.
Using Radar Odometry on Small Unmanned Aircraft

This paper develops an algorithm to estimate motion using a radar and ground targets. It involves estimating motion using an Extended Kalman Filter (EKF) with an Inertial Measurement Unit (IMU) and a side-looking Synthetic Aperture Radar (SAR) carried on a fixed wing aircraft flying over unknown, flat terrain. The accuracy of the motion estimation is compared to dead reckoning using only the IMU, with truth data being provided by a standard IMU/GPS Kalman filter. Initial results show that over 4.5km of simulated flight, position drift of around 300m resulted, as compared to 2.5km using only the IMU.
Improved Power Factor In Bridgeless Converter by Fuzzy Controlled Based SMPS Applications

power factor corrected (PFC) Switched Mode Power Supply (SMPS) based on bridgeless Buck-Boost converter topology with fuzzy logic control is proposed and is compared with the conventional SMPS. The multiple outputs of the SMPS are +12V,-12V, +5V,-5V for PC applications. To obtain nearly unity power factor and reduction in total harmonic distortion (THD) of input current, the SMPS with buck-boost converter based topology is designed to operate in discontinuous conduction mode (DCM). DCM operation gives added advantages of improved power factor and reduced switching losses and reduces the complexity of circuit operation. The presence of only two switches in the current conduction path during each switching cycle and the absence of diode bridge rectifier results in reduced conduction losses and an improved power factor, as compared to the conventional SMPS Single-phase ac supply is fed to a pair of back-to-back-connected buck–boost converters to eliminate the diode bridge rectifier, which results in reduction of conduction losses and power quality improvement at the front end. The operation of the bridgeless buck–boost converter in discontinuous conduction mode ensures inherent PFC operation and reduces complexity in control. To observe the performance of this converter, a model based on the Cuk topology has been designed and developed by using MATLAB/ SIMULINK software and implemented with Proportional-Integral (PI) and Fuzzy logic controller. The simulations are demonstrated in order to validate the effectiveness of the controllers in power factor improvement .
Cyclostratigraphy and rock‐magnetic investigation of the NRM signal in late Miocene palustrine‐alluvial deposits of the Librilla section (SE Spain)

[1] We constructed a high-resolution time frame for the cyclic continental palustrine-alluvial section of Librilla (SE Spain) which covers the onset of the Messinian salinity crisis in the marine realm. The section was dated earlier by Garces et al. [1998], using magnetostratigraphy. We resampled part of the section that contained a reversed overprint in detail to refine the magnetostratigraphy and to investigate the behavior of the natural remanent magnetization (NRM) signal. The detailed sampling yielded a better constrained position of the upper reversal of Chron C3An.1n. By counting the number of cycles in C3An.1n and taking into account the duration of this Chron, we were able to show that the basic sedimentary cycles in Librilla reflect climatic precession. Subsequently, the sedimentary pattern was tuned to the summer insolation curve, providing a high-resolution time. Two intervals of complex NRM behavior were identified, showing normal and reversed overprints. The reversed overprints seemed to be restricted mainly to gray palustrine layers. The analysis of coercivity components revealed no difference between samples with overprints or real NRM directions. We performed fuzzy c-means cluster analysis on a geochemical data set to link magnetic behavior to geochemical proxies, resulting in a three-cluster model that roughly describes lithology. Remarkably, all the samples with a normal overprint belong to one particular cluster. The reversed overprints, however, do not show any relation to the cluster partition. We favor the explanation of Garces et al. [1998] that the reversed overprint would be related to the Messinian salinity crisis.
Extreme ion heating in the dayside ionosphere in response to the arrival of a coronal mass ejection on 12 March 2012

Abstract. Simultaneous measurements of the polar ionosphere with the European Incoherent Scatter (EISCAT) ultra high frequency (UHF) radar at Tromso and the EISCAT Svalbard radar (ESR) at Longyearbyen were made during 07:00–12:00 UT on 12 March 2012. During the period, the Advanced Composition Explorer (ACE) spacecraft observed changes in the solar wind which were due to the arrival of coronal mass ejection (CME) effects associated with the 10 March M8.4 X-ray event. The solar wind showed two-step variations which caused strong ionospheric heating. First, the arrival of shock structures in the solar wind with enhancements of density and velocity, and a negative interplanetary magnetic field (IMF)-Bz component caused strong ionospheric heating around Longyearbyen; the ion temperature at about 300 km increased from about 1100 to 3400 K over Longyearbyen while that over Tromso increased from about 1050 to 1200 K. After the passage of the shock structures, the IMF-Bz component showed positive values and the solar wind speed and density also decreased. The second strong ionospheric heating occurred after the IMF-Bz component showed negative values again; the negative values lasted for more than 1.5 h. This solar wind variation caused stronger heating of the ionosphere in the lower latitudes than higher latitudes, suggesting expansion of the auroral oval/heating region to the lower latitude region. This study shows an example of the CME-induced dayside ionospheric heating: a short-duration and very large rise in the ion temperature which was closely related to the polar cap size and polar cap potential variations as a result of interaction between the solar wind and the magnetosphere.
Regular Tur\'an numbers

The regular Tur\'an number of a graph $F$, denoted by rex$(n,F)$, is the largest number of edges in a regular graph $G$ of order $n$ such that $G$ does not contain subgraphs isomorphic to $F$. Giving a partial answer to a recent problem raised by Gerbner et al. [arXiv:1909.04980] we prove that rex$(n,F)$ asymptotically equals the (classical) Tur\'an number whenever the chromatic number of $F$ is at least four; but it is substantially different for some 3-chromatic graphs $F$ if $n$ is odd.
HanaaAchram A thesis submitted as partial fulfilment of the requirements for the degree of Master of Science at the University of Otago, Dunedin, New Zealand Presented for marking March 2014

Phthalates are widely used in industrial processes and household products and as a result are amongst the most commonly encountered environmental pollutants worldwide. Humans are exposed to them directly via their use in cosmetics, medicines, as plasticisers in various ere they are ubiquitous contaminants due to their industrial, domestic, and agricultural uses. Dibutylphthalate (DBP) was widely used as an insecticide by New Zealand troops stationed in Malaya during the 1950s, and there are reports of increased rates of reproductive abnormalities in children of these veterans. This thesis set out to explore the possible effects of DBP exposure on genes that control testosterone metabolism. To do this, an appropriate cell line was selected, and DBP exposure experiments were conducted. Quantitative reverse transcriptase polymerase chain reaction assays for several key steroidal pathway genes were established, and used to explore possible effects of DBP exposure on expression of these genes. The HSD17, CYP17, CYP11 HSD3 and StAR genes were examined, and only changes in StAR gene expression due to DBP in high (1 w (0.1 studied. The results indicated that StAR mRNA was upregulated following exposure to a high dose of DBP in the THP1 cell line. On the other hand, exposure to medium and low doses of DBP showed no effect on StAR mRNA expression. Despite the limited results obtained in this study, analysis of gene expression changes in the THP1 cell line after exposure to DBP represents a potential model system that may be useful for future work in this area.
The Cleansing Effect of R&D Subsidies

The paper develops a patent race model of firms which differ in R&D productivity. It is demon-strated that R&D subsidies generate the cleansing effect where relatively lower productivity firms drop out of the race and innovation accelerates due to expanded R&D investment by the remaining firms and new entrants with higher productivity than those that exit.
3D non-LTE corrections for Li abundance and 6 Li/ 7 Li isotopic ratio in solar-type stars. I. Application to HD 207129 and HD 95456

Convective motions in solar-type stellar atmospheres induce Doppler shifts that affect the strengths and shapes of spectral absorption lines and create slightly asymmetric line profiles. 1D LTE studies of elemental abundances are not able to reproduce this phenomenon, which becomes particularly important when modeling the impact of isotopic fine structure, like the subtle depression created by the 6Li isotope on the red wing of the Li I resonance doublet line. The purpose of this work is to provide corrections for the lithium abundance, A(Li), and the 6Li/7Li ratio that can easily be applied to correct 1D LTE lithium abundances in G and F dwarf stars of approximately solar mass and metallicity for 3D and non-LTE (NLTE) effects. The corrections for A(Li) and 6Li/7Li are computed using grids of 3D NLTE and 1D LTE synthetic lithium line profiles, generated from 3D hydro-dynamical CO5BOLD and 1D hydrostatic model atmospheres, respectively. The 3D NLTE corrections are then approximated by analytical expressions as a function of the stellar parameters. These are applied to adjust the 1D LTE isotopic lithium abundances in two solar-type stars, HD 207129 and HD 95456. The derived 3D NLTE corrections range between -0.01 and +0.11 dex for A(Li), and between -4.9 and -0.4% for the 6Li/7Li ratio, depending on the adopted stellar parameters. In the case of the 6Li/7Li ratio, our corrections are always negative, showing that 1D LTE analysis can significantly overestimate (up to 4.9 percentage points) the presence of 6Li in the atmospheres of solar-like dwarf stars. These results emphasize the importance of reliable 3D model atmospheres combined with NLTE line formation for deriving precise isotopic lithium abundances. Although 3D NLTE spectral synthesis implies an extensive computational effort, the results can be made accessible with parametric tools like the ones presented in this work.
Paravertebral Blocks : The Evolution of a Standard of Care

Since that time, the technique has experienced extraordinary growth. As was the case initially, it is considered to be safer than neuraxial blocks—and particularly the thoracic epidural—for perioperative analgesia. The importance of this comparison is highlighted by the increased number of surgical and trauma patients who receive enoxaparin for thromboprophylaxis, a clear contraindication for the use of an epidural. At the University of Pittsburgh Medical Center (UPMC), the paravertebral technique was introduced in 2003 as a single block for the perioperative management of patients undergoing open radical prostatectomy. This method was soon followed by the use of continuous paravertebral blocks (CPVBs) for the perioperative management of pain in patients undergoing thoracic surgery. Between July 1, 2010, and June 30, 2011, a total of 8,637 paravertebral blocks (PVBs) were performed, including the placement of 6,747 continuous paravertebral catheters.
Impact of Customer Relationship Management Practices on Customer’s Satisfaction in Jordan Ahli Bank and Bank Al-Etihad

Customer relationship management (CRM) is a combination of people, processes and technology that seeks to understand a company’s customers. It has been found that successful implementation of CRM results in customer loyalty and long run profitability and therefore companies are focused on maintaining harmonious relationships with customers. The present research has been undertaken to study the impact of Customer Relationship Management (CRM) practices on customer’s satisfaction in two Jordanian Banks namely Jordan Ahli Bank India and Bank Al Etihad. A sample of 119 customers has been selected for the study. Data have been collected through questionnaire designed on a five point Likert scale. Independent sample t-test has been used as the statistical tool to measure the variation in CRM on the variables namely reliability, responsiveness, assurance, empathy and customer relations. The analysis of the data revealed that significant variation exists in the perception of customers in Jordan Ahli Bank India and Bank Al Etihad.
New results on $\nu_\mu \to \nu_\tau$ appearance with the OPERA experiment in the CNGS beam

The OPERA neutrino experiment is designed to perform the first observation of neutrino oscillations in direct appearance mode in the $\nu_\mu \to \nu_\tau$ channel, via the detection of the $\tau$-leptons created in charged current $\nu_\tau$ interactions. The detector, located in the underground Gran Sasso Laboratory, consists of an emulsion/lead target with an average mass of about 1.2 kt, complemented by electronic detectors. It is exposed to the CERN Neutrinos to Gran Sasso beam, with a baseline of 730 km and a mean energy of 17 GeV. The observation of the first $\nu_\tau$ candidate event and the analysis of the 2008-2009 neutrino sample have been reported in previous publications. This work describes substantial improvements in the analysis and in the evaluation of the detection efficiencies and backgrounds using new simulation tools. The analysis is extended to a sub-sample of 2010 and 2011 data, resulting from an electronic detector-based pre-selection, in which an additional $\nu_\tau$ candidate has been observed. The significance of the two events in terms of a $\nu_\mu \to \nu_\tau$ oscillation signal is of 2.40 $\sigma$.
The imprint of Gould's Belt on the local cosmic-ray electron spectrum

Recent analyses have shown that if the sources of cosmic-rays are discrete, as are supernova remnants, then the spectra of cosmic-ray electrons vary greatly with location and time and the locally measured electron spectrum may be not representative of the electron spectra elsewhere in the Galaxy. We have continued the earlier studies by investigating the impact of the star forming region Gould's Belt on the local electron spectrum at GeV to TeV energies. Our results indicate that if the electron sources in Gould's Belt are continous, the local electron spectrum would be slightly hardened with a spectral index increase of ∆s ≈ 0.07 due to the higher SN rate in the Belt. If the electron sources are discrete, which is the more probable case, the local electron spectrum above ∼30 GeV is variable with similar amplitude as without Gould's Belt. By the method of Monte Carlo, we have also studied the correlation of the local electron flux with that in nearby molecular cloud complexes. The high energy electron flux above 30 GeV near the Orion, Monoceros, Cassiopeia, Cepheus, and Perseus clouds does not vary in coordination with the local flux, but a correlation between the electron flux in the Taurus and Ophiuchus clouds and that in solar vicinity is indicated by our study, implying that the spatial correlation length is of the order of 200 pc at electron energies of 100 GeV and higher. This would permit hard γ-ray spectra from inverse Compton scattering to be produced in the more distant clouds, in agreement with the GeV excess observed towards Orion and Monoceros, without affecting the emissivity spectra of the very nearby clouds as in Taurus and Ophiuchus.