Miracle-dz/UniFAR-FTUs huggingface dataset:
Predictive value of baseline C-reactive protein level in patients with stable coronary artery disease: A meta-analysis

Background: Conflicting results have been reported on the association of C-reactive protein (CRP) level with adverse outcomes in patients with stable coronary artery disease (CAD). The objective of this meta-analysis was to evaluate the predictive value of baseline CRP level in stable CAD patients. Methods: Two reviewers independently searched PubMed and Embase databases from their inception to November 28, 2021 to identify studies assessing the value of baseline CRP level in predicting adverse outcomes in stable CAD patients. The endpoints of interest included cardiovascular mortality, all-cause mortality, or major adverse cardiovascular events (MACEs). The predictive value of CRP level was estimated by pooling the multivariable adjusted risk ratio with 95% confidence intervals (CI) compared the highest to the lowest CRP level. Results: Twenty-six studies involving of 22,602 patients with stable CAD satisfied the inclusion criteria. In a comparison of the highest with the lowest CRP level, the pooled multivariable adjusted risk ratio was 1.77 (95% CI 1.60–1.96) for MACEs, 1.64 (95% CI 1.13–2.33) for cardiovascular mortality, and 1.62 (95% CI 2.62–5.12) for all-cause mortality, respectively. Subgroup analyses indicated that the values of elevated CRP level in predicting MACEs were consistently observed in each subgroup. Conclusion: Elevated baseline CRP level was an independent predictor of MACEs, cardiovascular mortality, and all-cause mortality in patients with stable CAD. Baseline CRP level can provide important predictive information in stable CAD patients.
Three-dimensional viscous rotor flow calculations using boundary-layer equations

A three-dimensional viscous-inviscid interaction analysis has been developed to predict the performance of rotors in hover and forward flight at subsonic and transonic tip speeds. The analysis solves the full-potential and boundary-layer equations by finite-difference numerical procedures. Calculations were made for several different model rotor configurations in hover and forward flight at subsonic and transonic tip speeds. The results were compared with predictions from a two-dimensional integral method and with experimental data. The comparisons show good agreement between test data and predictions.
Spin glasses : a challenge for mathematicians : cavity and mean field models

0. Introduction. - 1. A Toy Model, the REM. - 2. The Sherrington-Kirkpatrick Model. - 3. The Capacity of the Perceptron: The Ising Case. - 4. Capacity of the Perceptron: The Gaussian and the Spherical Case. - 5. The Hopfield Model. - 6. The p-Spin Interaction Model at Low Temperature. - 7. The Diluted SK Model and the K-Sat Problems. - 8. An Assignment Problem. - A. Appendix. - Elements of Probability Theory. - References. - Index.
A Flexible P2P Gossip-based PSO Algorithm

—It is becoming more and more interesting, in the domain of distributed function optimization, the study of fully de-centralized optimization algorithms, deployed on large networks of heterogeneous computational units. Several issues arise on such a system design, among which the proper way of distributing and making use of shared information, in absence of a centralized coordination, is a prominent one. We introduce the design of a P2P gossip-based Particle Swarm Optimization (PSO) algorithm, that is capable to implement different policies with respect to the use of global information, as this becomes available via gossiping during the computation. Such a PSO ﬂavor is easy to tune, in order to implement different strategies, while balancing exploration and exploitation. Preliminary experimental results are shown to assess the usefulness of the proposal.
Impacts of an aerosol layer on a midlatitude continental system of cumulus clouds: how do these impacts depend on the vertical location of the aerosol layer?

Abstract. Effects of an aerosol layer on warm cumulus clouds in the Korean Peninsula when the layer is above or around the cloud tops in the free atmosphere are compared to effects when the layer is around or below the cloud bases in the planetary boundary layer (PBL). For this comparison, simulations are performed using the large-eddy simulation framework. When the aerosol layer is in the PBL, aerosols absorb solar radiation and radiatively heat up air enough to induce greater instability, stronger updrafts and more cloud mass than when the layer is in the free atmosphere. Hence, there is a variation of cloud mass with the location (or altitude) of the aerosol layer. It is found that this variation of cloud mass is reduced as aerosol concentrations in the layer decrease or aerosol impacts on radiation are absent. The transportation of aerosols by updrafts reduces aerosol concentrations in the PBL. This in turn reduces the aerosol radiative heating, updraft intensity and cloud mass.
Hepatitis B Virus-Infected HepG2 hNTCP Cells Serve as a Novel Immunological Tool To Analyze the Antiviral Efﬁcacy of CD8 (cid:2) T Cells In Vitro

CD8 T cells are the main effector lymphocytes in the control of hepatitis B virus (HBV) infection. However, limitations of model systems, such as low infection rates, restrict mechanistic studies of HBV-speciﬁc CD8 (cid:2) T cells. Here, we established a novel immunological cell culture model based on HBV-infected HepG2 hNTCP cells that endogenously processed viral antigens and presented them to HBV-speciﬁc CD8 (cid:2) T cells. This induced cytolytic and noncytolytic CD8 (cid:2) T-cell effector functions and reduction of viral loads.
Precision of Infrared Cameras in Imaging Power Electronics Elements

Abstract – The electrical power within electronic components is connected with large quantity heat discharge which has to be removed in order to avoid risk of failure due to overheating. This paper presents an analysis of infrared camera implementation for correct temperature field estimation. This is necessary regarding the temperature measurement specifics with regard to power electronic elements during different regimes of exploitation. An infrared thermal camera Flir i7 has been used. Test measurements are performed and the influence of main measurement parameters over the thermal radiation of the bodies is discussed. Regression equation for temperature correction is calculated.
Identiﬁcation of Prebiotic Fructooligosaccharide Metabolism in Lactobacillus plantarum WCFS1 through Microarrays (cid:1)

Short-chain fructooligosaccharides (scFOS) and other prebiotics are used to selectively stimulate the growth and activity of lactobacilli and biﬁdobacteria in the colon. However, there is little information on the mechanisms whereby prebiotics exert their speciﬁc effects upon such microorganisms. To study the genomic basis of scFOS metabolism in Lactobacillus plantarum WCFS1, two-color microarrays were used to screen for differentially expressed genes when grown on scFOS compared to glucose (control). A signiﬁcant up-regulation (8- to 60-fold) was observed with a set of only ﬁve genes located in a single locus and predicted to encode a sucrose phosphoenolpyruvate transport system (PTS), a (cid:1) -fructofuranosidase, a fructokinase, an (cid:2) -glucosi-dase, and a sucrose operon repressor. Several other genes were slightly overexpressed, including pyruvate dehydrogenase. For the latter, no detectable activity in L. plantarum under various growth conditions has been previously reported. A mannose-PTS likely to encode glucose uptake was 50-fold down-regulated as well as, to a lower extent, other PTSs. Chemical analysis of the different moieties of scFOS that were depleted in the growth medium revealed that the trisaccharide 1-kestose present in scFOS was preferentially utilized, in comparison with the tetrasaccharide nystose and the pentasaccharide fructofuranosylnystose. The main end products of scFOS fermentation were lactate and acetate. This is the ﬁrst example in lactobacilli of the association of a sucrose PTS and a (cid:1) -fructofuranosidase that could be used for scFOS degradation.
Theoretical Study of the Electronic Properties of the Curcumin Molecule: Using Density Functional Theory

This search aims to study electronic properties of the curcumin moleculewhich exist in two isomers, ketone and enol forms, and the effect of usingdifferent basis setsby relying on density functions theory (DFT) at B3LYP level. The hydrogen atom transfer from the central methylene (CH 2 ) group to an oxygen atom to form strong intra-molecular hydrogen (O H) bond causes geometrical changes in two isomers; where the enol form is structure approximately planar but not completely planar for the ketone form.The results showed that the 6-311G+(d,p) basis set gave sat- isfactory results for calculations. As well as the findings of each of the total energy, the energy of the high occupied molecular orbital and energy gap confirm that the isomer ketone is more stable than isomer enol. Also the ketone has a high electron-accepting, as was proven by the values of the energy of lower unoccupied molecular orbital,ionization potential, electron affinity and electronegativity.
The individual and combined effects of the angiotensin-converting enzyme gene insertion/deletion polymorphism and endurance training status on muscle oxygen saturation markers during incremental cycle ergometer test

Introduction: (ACE I/D genotype) has been one of the first and most investigated possible gene marker for physical performance. However, studies investigating the association between the ACE I/D genotype and peak oxygen uptake (VO 2peak ) were not conclusive (Papadimitriou et al., 2018; Rankinen et al., 2000; Sonna et al., 2001). On the contrary, studies which have focused on skeletal muscle had more success (Valdivieso et al., 2017; Vaughan et al., 2016; Vaughan, Huber-Abel, Graber, Hoppeler, & Flück, 2013; Zhang et al., 2003). Muscle monitors based on near-infrared spectroscopy (NIRS) offer the possibility of non-invasive measurement of skeletal muscle oxygenation during exercise. Therefore, the aim of this study was to find out whether there are individual and combined effects of the ACE I/D genotype and endurance training status on markers of muscle oxygen saturation (SmO 2 ) during ramp test. Methods: 21 non-specific trained subjects completed an incremental cycle ergometer test (ramp test) and were genotyped for the ACE I/D genotype. During ramp test VO 2peak was measured with a breath-by-breath system. SmO 2 of the m. vastus lateralis was measured using a NIRS device. The individual and combined effects of the ACE I/D genotype and endurance training status on SmO 2 markers during ramp test were analysed using two factor analysis of variance (ANOVA). Results: ACE I/D genotype did not have a significant effect on any of the SmO 2 markers during ramp test. Endurance training status had a significant effect on the markers SmO 2 min ( p = 0.017) and ∆ deoxygenation ( p = 0.033) and a highly significant effect on the marker ∆ 1/2 reoxygenation ( p = 0.007). In addition, there was a significant interaction effect between the ACE I/D genotype and training status on the marker slope deoxygenation ( p =
J urnal Ketopong Pendidikan A Trinitarian Perspective of Transformational Leadership

The practice of Christian leadership is influenced by the understanding of who God is and His work. The monistic view of God leads to a monistic leadership approach. With the redevelopment of the doctrine of Trinity, many implications are discussed, including in leadership. Christian leaders are exposed to many leadership theories. One of those is Transformational Leadership which is very appealing to Christian leaders. Yet, Christian leaders must develop their understanding and practice of leadership from what they believe about God and His works. This writing will discuss the trinitarian perspectives in developing a Christian foundation for transformational leadership, using literature review on the topic of leadership based on the Trinitarian perspectives, comparing with the transformational leadership theory. Three suggestions are presented to be considered by Christian leaders in practicing transformational leadership from Trinitarian perspectives, shared leadership, mission-centred, and creating space for the Holy Spirit. Oh Yen Nie | Trinitarian Perspective of Transformation
A kinetic energy preserving nodal discontinuous Galerkin spectral element method

In this work, we discuss the construction of a skew‐symmetric discontinuous Galerkin (DG) collocation spectral element approximation for the compressible Euler equations. Starting from the skew‐symmetric formulation of Morinishi, we mimic the continuous derivations on a discrete level to find a formulation for the conserved variables. In contrast to finite difference methods, DG formulations naturally have inter‐domain surface flux contributions due to the discontinuous nature of the approximation space. Thus, throughout the derivations we accurately track the influence of the surface fluxes to arrive at a consistent formulation also for the surface terms. The resulting novel skew‐symmetric method differs from the standard DG scheme by additional volume terms. Those volume terms have a special structure and basically represent the discretization error of the different product rules. We use the summation‐by‐parts (SBP) property of the Gauss–Lobatto‐based DG operator and show that the novel formulation is exactly conservative for the mass, momentum, and energy. Finally, an analysis of the kinetic energy balance of the standard DG discretization shows that because of aliasing errors, a nonzero transport source term in the evolution of the discrete kinetic energy mean value may lead to an inconsistent increase or decrease in contrast to the skew‐symmetric formulation. Furthermore, we derive a suitable interface flux that guarantees kinetic energy preservation in combination with the skew‐symmetric DG formulation. As all derivations require only the SBP property of the Gauss–Lobatto‐based DG collocation spectral element method operator and that the mass matrix is diagonal, all results for the surface terms can be directly applied in the context of multi‐domain diagonal norm SBP finite difference methods. Numerical experiments are conducted to demonstrate the theoretical findings. Copyright © 2014 John Wiley & Sons, Ltd.
Free Vibration Analysis of Bulkhead-Stiffened Functionally Graded Open Shell Using a Meshless Method

This paper focuses on the free vibration analysis of bulkhead-stiffened functionally graded open shell (FGOS) by means of the first-order shear deformation theory (FSDT) and the meshless strong form method. The bulkhead-stiffened FGOS is decomposed into several segments without bulkhead, and the equations of motion and boundary conditions for each segment are discretized by meshless strong form method, and the displacement components are approximated using meshfree Legendre–RIPM shape function using the combined basis of multi-quadrics (MQ) radial function and Legendre polynomials. The continuous conditions of displacement are applied at the interfaces between segments. The boundary and continuous conditions are enforced by using the artificial spring technique. The accuracy and reliability of the current method are validated by comparing the present results with those of the kinds of literature and the finite element program ABAQUS. The effects of some geometrical parameters and boundary conditions on the natural frequencies of bulkhead-stiffened FGOS are investigated through numerical examples, which may serve as benchmark data.
Superior Replacement of Medicinal Gel With Ayurvedic Nanogel as a Coupling Medium for Electrotherapeutic Treatment of Osteoarthritis: A Review Article

Osteoarthritis is a disabling condition globally, affecting a major population. The non-invasive conservative management of osteoarthritis is majorly catered to by physical therapy rehabilitation. Research has been conducted to evaluate the impact of the most commonly used electrotherapy modality, therapeutic ultrasound, on reducing pain and increasing functional activities in individuals suffering from osteoarthritis, but the condition is still, after over two decades of research, growing rapidly in its prevalence. Therefore, the aim of our study was to analyze the literature and compare the evolving trends in coupling medium used for the application of therapeutic ultrasound in arthritic conditions of musculoskeletal origin. Databases of PubMed, Web of Science, Embase, Pedro, and Cochrane were searched till June 2022. The outcome measures used were to detect the status of pain and improvement in functional status. Overall ultrasound therapy adjunct to exercise program was found to be superior to either ultrasound therapy or exercise program alone for the management of pain and functional status of the patients. Additionally, phonophoresis was deduced to have shown better pain relief than conventional ultrasound. Phonophoresis was done using non-steroidal anti-inflammatory drugs and Ayurvedic medicinal herbs in the form of Nano gel.
Application of a Low-Cost Electronic Nose to Detect of Forest Tree Pathogens: Fusarium oxysporum and Phytophthora plurivora

The presence of forest tree pathogens may lead to substantial problems and their early detection during seed storage or in nurseries may be critical for the choice of appropriate management strategy. A new construction of a low-cost electronic nose was tested on the samples of pathogenic fungi and oomycetes of Fusarium oxysporum and Phytopthora plurivora. The electronic nose uses Figaro Inc. TGS series sensors with applied heater voltage modulation. Such a mode of electronic nose operation may be more appropriate for application for constant monitoring of seeds storage, when we compare it to the method making use of modulation of the gas concentration. A rectangular shape of the sensors’ heater voltage modulation pattern, with a shallow drop of the heater voltage from the nominal voltage, was proposed. Data visualization using the principal component analysis method and the random forest machine learning technique was used to build classification models. A classification accuracy of 97% was obtained by a fusion of data collected by TGS 2610 and TGS 2602 sensors.
In vitro evaluation of novel designed, and synthesized naproxen derivatives bearing 1,2,4 triazole moiety

The Objective of this study is created a novel derivative of the naproxen with the heterocyclic (1,2 and 4 the triazole) ring that reacted with benzoyl chloride derivatives, as well as preliminary antibacterial activity testing of the formed products. The derivatives are synthesized by esterifying naproxen hydrazine hydrate, then reacting with hydrated hydrazine and carbon disulfide, and finally reaction the benzoyl chloride derivatives (in the final step) with the triazole the derivatives of the naproxen including of amino group via a nucleophilic substitution reaction. In addition to naproxen, the antibacterial properties of the novel compounds (Va-Vd) were evaluated in agar at known doses (IN vivo). The antibacterial action of the compounds Va and Vd against staph was demonstrated in the topmost inhibited zone. In the case of E. coli, compound Vb has the smallest inhibitory zone. The findings of this study have implications to produce naproxen 1,2 and 4 the triazole-three-thiol derivatives, which reacted including the variety of benzoyl chloride derivatives. The potential of naproxen will be affected by the attraction of benzoyl chloride derivatives with para-groups on the benzen ring.
Title: Factors that Increase Risk of Celiac Disease Autoimmunity Following a Gastrointestinal Infection in Early Life Short title: Infections and celiac disease in early life

Authors’ Institutions: 1 Department of Microbiology and Cell Science, University of Florida, Gainesville, USA 2 Health Informatics Institute, University of South Florida, Tampa, USA 3 Digestive Health Institute, Children’s Hospital Colorado; Barbara Davis Center, University of Colorado Denver, Aurora, USA 4 Department of Virology, School of Medicine, University of Tampere, Tampere, Finland; Department of Dermatology, Tampere University Hospital, Tampere, Finland 5 MediCity Laboratory, University of Turku, Turku, Finland 6 Center for Infection and Immunity, and Department of Epidemiology, Mailman School of Public Health, Columbia University, New York, USA 7 Dr. von Hauner Children’s Hospital, Ludwig Maximilian University, Munich, Germany 8 Pacific Northwest Diabetes Research Institute, Seattle, USA 9 Center for Biotechnology and Genomic Medicine, Medical College of Georgia, Georgia Regents University, Augusta, USA
Relevance of ERK1/2 Post-retrieval Participation on Memory Processes: Insights in Their Particular Role on Reconsolidation and Persistence of Memories

Back in 1968, Misanin and his group posited that reactivation of consolidated memories could support changes in that trace, similar to what might happen during the consolidation process. Not until 2000, when Nader et al. (2000) studied the behavioral effect of a protein synthesis inhibitor on retrieved memories, could this previous statement be taken under consideration once again; suggesting that consolidated memories can become labile after reactivation. The process of strengthening after memory labilization was named memory reconsolidation. In recent years, many studies pointed towards a critical participation of the extracellular signal-regulated kinase (ERK)/mitogen activated protein kinases (MAPKs) pathway in different memory processes (e.g., consolidation, extinction, reconsolidation, among others). In this review article, we will focus on how this system might be modulating the processes triggered after retrieval of well-consolidated memories in mice.
Further results on H ∞  control for discrete‐time uncertain singular systems with interval time‐varying delays in state and input

This paper investigates the state feedback robust H ∞ control problem of a class of discrete‐time singular systems with norm‐bounded uncertainties and interval time‐varying delays in state and input. A new bounded real lemma for discrete‐time singular systems with a pair of time‐varying interval state delays is first investigated. Mathematical comparisons of the new bounded real lemma and two existing ones are presented. Then, on the basis of the bounded real lemma proposed here, a sufficient condition in the form of nonlinear matrix inequality, such that the considered state feedback robust H ∞ control problem is solvable, is given. In order to solve the nonlinear matrix inequality, a cone complementarity linearization algorithm is offered. Several numerical examples are presented to show the applicability of the proposed approach. Copyright © 2012 John Wiley & Sons, Ltd.
Elucidating the Neurobiologic Etiology of Comorbid PTSD and Substance Use Disorders

Early childhood maltreatment and other traumatic event experiences (“trauma”) are common among youth, including those with substance use problems including substance use disorders (SUD). Particularly, interpersonal violence is associated with high rates of comorbidity between posttraumatic stress disorder (PTSD) and SUD, and these comorbid disorders exhibit high levels of overlapping symptomatology. Theoretical models proposed to explain the bidirectional relationship between PTSD and SUD include the self-medication hypothesis and susceptibility hypothesis. In this article, we explore neurobiologic changes associated with trauma, PTSD, and SUD that underly dysregulated stress response. Examining lessons learned from recent translational and clinical research, we propose that further elucidating the neurobiologic etiology of comorbid PTSD and SUD will require a collaborative, interdisciplinary approach, including the integration of preclinical and clinical studies, exploration of biologic markers in clinical studies, and accumulation of larger studies and longitudinal studies with the power to study PTSD and SUD. Such research can transform the field and ultimately reduce high rates and costly impairment of co-occurring PTSD and SUD across the lifespan.