Miracle-dz/UniFAR-FTUs huggingface dataset:
The Homeobox Gene ATNl of Arabidopsis 1s Derepressed in the Photomorphogenic Mutants copl and detl

A light-regulated Arabidopsis thaliana homeobox 1 gene (ATH1) was identified in a transcription factor gene collection. Primer extension analysis of this gene showed the presence of two major transcripts with unusually long 5' untranslated leader sequences. The leader sequence of the isolated cDNA clone contains several small open reading frames upstream of the initiation codon of the largest open reading frame coding for the homeodomain protein. This leader sequence was found to affect the translation efficiency negatively in an in vitro translation system. The expression of the ATHl gene is dependent on the presence of light. After illuminating etiolated or dark-adapted Arabidopsis seedlings, the ATHl mRNA level increased rapidly. Expression of ATHl does not require the presence of active chloroplasts because photooxidative destruction of the chloroplast by norflurazon treatment did not influence the ATH7 mRNA level. In dark-grown seedlings of the photomorphogenic constitutiwe photomorphogenic 1 (copl) and deetiolated 1 (detl) mutants, the ATHl mRNA level was elevated. This shows that the gene products of these loci directly or indirectly repress ATH1 expression in etiolated wild-type seedlings. A correlation between the strength of the copl allele and the ATHl mRNA level was found. This relationship suggests a role for the ATHl protein in the signal transduction pathway downstream of COPl. Brusslan and for the protocol for the RNase protec- tion assay and for the gift of pAB140; Dr. P. Timko for his gift of pATS22; Dr. for the gift of p3-1500-18s; Dr. Pilon for the assistance with in vitro translation procedures; Dr. Angenent for the construction of the Arabidopsis cDNA library; of the European Union BRIDGE Arabidopsis project for the distribution of the genomic IGEM-11 libraryconstructed by Dr. John Mulligan and Dr. Ron Davis and Dr. Oscar Vorst for critical reading of the manuscript. Sequence analysis supported by the ESSA (European Scientists Sequencing Arabidopsis) project of European Union.
CellsInduction by Liver Sinusoidal Endothelial Dynamic Regulation of CD8 T Cell Tolerance

Cross-presentation of soluble Ag on MHC class I molecules to naive CD8 T cells by liver sinusoidal endothelial cells (LSECs) leads to induction of T cell tolerance that requires interaction between coinhibitory B7-H1 on LSECs and programmed cell death-1 on CD8 T cells. In this study, we investigate whether cross-presentation of high as well as low Ag concentrations allowed for LSEC-induced tolerance. Ag concentration directly correlated with the cross-presentation capacity of murine LSECs and thus strength of TCR stimulation. Although LSEC cross-presentation at low-Ag concentrations resulted in tolerance, they induced differentiation into effector T cells (CTL) at high-Ag concentrations. CTL differentiation under these conditions was not caused by increased expression of costimulatory CD80/86 on cross-presenting LSECs but was determined by early IL-2 release from naive CD8 T cells. B7-H1 signals from LSECs and TCR avidity reciprocally controlled early T cell release of IL-2 and CTL differentiation. B7-H1 expression directly correlated with cross-presentation at low- but not high-Ag concentrations, indicating an imbalance between TCR and coinhibitory signals regulating T cell release of IL-2. Exogenous IL-2 overrode coinhibitory B7-H1–mediated signals by LSECs and induced full CTL differentiation. Our results imply that LSEC-mediated T cell tolerance can be broken in situations where T cells bearing high-avidity TCR encounter LSECs cross-presenting high numbers of cognate MHC class I peptide molecules, such as during viral infection of the liver. Furthermore, we attribute a novel costimulatory function to IL-2 acting in a T cell autonomous fashion to promote local induction of immunity in the liver
Growth and mycorrhizal responses to cadmium stress in some halophytic plants

The phytoremedial potential of three halophytes and the role of arbuscular mycorrhizal fungi (AMF) isolated from heavy metal contaminated soil under cadmium stress were studied. The plants were treated with different Cd concentrations (0, 50, 200, and 400 µM) with and without AMF inoculation. On the plant growth, AMF inoculation to all species resulted in increased biomass, shoots and roots length, and leave number compared to control (non-inoculated) plants, especially in Limbarda crithmoides, where no mortality was detected neither in controls nor inoculants. Furthermore, L. crithmoides and Atriplex canescens recorded higher values of relative mycorrhizal dependency and water content. The arbuscular mycorrhizal association was observed in all host plants and was not affected by cadmium. Our results indicate that studied halophytes can tolerate high Cd concentrations due to the support of AMF, particularly in Atriplex halimus association with AMF in pot experiment which was recorded for the first time.
Flute Melody Composition from Hindustani Vocal Music using Motifs Substitution Technique

— In the music industry, synthesis of vocal sound tracks into instrumental melodies is an arduous and manual process that needs the input of musicians who are specialized in the target instruments. This process is rather expensive and time consuming. In this paper, we propose an automated means of transforming vocal sounds tracks to instrumental melodies that preserves the tonality and pitch of the original. This is done by the means of a technique that is introduced in this paper called the 'Motifs Substitution Technique". As a proof-of-concept, we show how we can convert vocal sound tracks sung in the Hindustani Classical style, which is a North Indian style of Indian Classical Music, into a flute melody.
Evaluation of the Biological Efficacy of Fungus and Bacteria Isolated from Mushroom Substrates against Pathogenic Fungi

— In vitro efficacy of fungus and bacteria isolated from mushroom substrates were evaluated against selected pathogens (Fusarium oxysporum, Sclerotium rolfsii, and Colletotrichum corchori). There were four fungi Aspergillus flavus, Aspergillus niger, Trichoderma harzianum, and Penicilliumsp and four bacteria Bacillus subtilis, Bacillus cereus, Pseudomonas sp. and Paenibacillus polymyxa isolated from substrate. Different biochemical and pathogenicity test were performed to confirm their species. In in-vitro dual culture method T. harzianum showed the highest inhibition in case of Fusarium oxysporum (70.26%) followed by Sclerotium rolfsii (59.94%) and Colletotrichum corchori (57.02%) whereas Penicillium sp showed the least significant result against these pathogens. To inhibit the growth of Sclerotium rolfsii and F. oxysporum. Pseudomonas spp. was significant around 72.19% and 62.62% respectively. On a comparative study among the four isolated bacteria and fungi Pseudomonas sp. and T. harzianum showed the best significant antagonistic activity against all the selected plant pathogenic fungi.
Probing £agellar promoter occupancy in wild-type and mutant Caulobactercrescentusby chromatin immunoprecipitation

In the asymmetric predivisional cell of Caulobacter crescentus , TipF and TipN mark the cellular pole for future ﬂagellar development. TipF is essential for motility and contains a cyclic-di-GMP phosphodiesterase-like (EAL) domain that is necessary for proper function. TipN is localized to the ﬂagellar pole before TipF and is essential for the proper placement of the ﬂagellum in C . crescentus . Using b galactosidase promoter-probe assays and quantitative chromatin immunoprecipitation, we investigated the inﬂuence of the C . crescentus ﬂagellar assembly regulator TipF on ﬂagellar gene transcription. We compared the transcriptional activity of class II- ﬂiF - lacZ , class III- ﬂgE - lacZ , and class IV- ﬂjL - lacZ fusions in a D tipF mutant with that of other ﬂagellar mutants and the wild-type strain. We subsequently veriﬁed the in vivo occupancy of the ﬂiF , ﬂgE , and ﬂjL ﬂagellar promoters by the ﬂagellar regulators CtrA, FlbD, and FliX in addition to RNA polymerase. We deduce that TipF contributes to proper expression of ﬂagellar genes in C . crescentus by acting both within and outside of the canonical ﬂagellar gene expression hierarchy. < Tn5, and ﬂbD < Tn5 strains. Promoter regions were immuno-precipitatedwith a polyclonal antibodyto CtrA or a monoclonal antibody to the RpoC subunit of RNAP before analyses by quantitative real-time PCR. Results demonstrate the percentage of promoter occupancy by CtrA and RNAP relative to WT .
Efficient Algorithm for the Non-(cid:40)(cid:84)(cid:88)(cid:79)(cid:76)(cid:69)(cid:85)(cid:76)(cid:88)(cid:80)(cid:86)(cid:3)(cid:42)(cid:85)(cid:72)(cid:72)(cid:81)(cid:182)(cid:86)(cid:3)

(cid:178) We present an efficient algorithm for numerical simulations of charge transport through semiconductor nanostructures performed within (cid:87)(cid:75)(cid:72)(cid:3) (cid:42)(cid:85)(cid:72)(cid:72)(cid:81)(cid:182)(cid:86)(cid:3) (cid:73)(cid:88)(cid:81)(cid:70)(cid:87)(cid:76)(cid:82)(cid:81)(cid:3) formalism. The commonly used algorithm to compute the conductance of nanostructures in this formalism has been adapted for parallel execution on both multicore computers and general-purpose graphics processing units (GPU) in a memory-efficient way to allow simulations of devices with realistic dimensions. Keywords
Fast Fourier Transform on the Versat CGRA

—In this paper we present a Fast Fourier Transform (FFT) algorithm for the Versat architecture, a small and low power Coarse Grained Reconﬁgurable Array (CGRA). This approach targets ultra low energy applications such as those found in Wireless Sensor Networks (WSNs), where using a GPU or FPGA accelerator is out of the question. The implementation chosen was the Radix-2 FFT, and uses 32-bit integer precision in the Q1.31 format. The Versat program creates two base hardware datapaths for the two basic steps of the algorithm: the complex multiplication and the complex addition steps. These datapaths are partially reconﬁgured during execution. The program has been written in assembly and has 873 instructions. It is fully parameterizable with the number of datapoints, FFT window size, overlap size and memory pointers for reading and writing back the data to the external memory. The results show that the new Versat core is 9.4x smaller than an ARM Cortex A9 core, runs the algorithm on average 18x faster and consumes 219.51x less energy.
Expressing the conﬁguration of the equipment and its characteristics in discharge lines of pumping wells

The problem of information management of pumping stations is discussed. As a step towards its solution, a graphical language aimed at expressing the conﬁguration of discharge lines is introduced in the context of an information system for water administration, and it is formally described by its syntactic and semantic rules. Its incorporation into the information system by means of an adequate user interface is shown, and it is concluded that tools like this are very useful in the gathering of large amounts of pumping stations’ information.
Enabling Social and Distributed Interaction in the Future 3D Internet 1

Current trends in 3D visualization merged with internet applications and sensor technologies will soon break the barriers to the widespread acceptance of 3D Internet, and they will enable a full user immersion in the virtual world. However this evolution will impact dramatically on the existing infrastructures since the fruition of 3D content in real time by a huge number of people poses new issues related to the system responsiveness and to the ability of managing context information. In this paper we observe that actions related to the acquisition of context from the physical and from the virtual worlds, as well as actuation in both worlds can be considered as a special case of context management and actuation. For this reason we propose a architecture for the management of such aspects within a unique framework, and an experimental testbed that validates the architecture.
MRI Brain Edge Detection Using GAFCM Segmentation and Canny Algorithm

— Over the past few decades we have seen tremendous growth in the field of Magnetic Resonance Imaging (MRI) Brain image processing. It requires various steps to ensure that the desired result is obtained. One of the constituent processes for the basic study of the brain parts is the edge detection, which is the initial module for all other post processing procedures. These edges characterize the abnormalities existing in the human brain. Hence it should be done with utmost care for obtaining worthy result. In this paper, a new approach to MRI brain edge detection problem is presented. It consists of two stages. First the original MRI image is passed through image segmentation block and in the second stage edge detection algorithm is applied to the segmented image. Image segmentation is done using Genetic algorithm incorporating Fuzzy C means clustering (GAFCM) and Canny edge detection Algorithm is used for edge detection. Although this approach has high computational complexity it greatly improves the accuracy of the segmentation on medical image that produces precise edge detected image of the Human Brain.
Data Hiding in Video Streaming by Code Word Substitution

-Data hiding techniques can be used to embed a secret message and secret image into a video bit stream for copyright protection, access control and transaction tracking. They are some data hiding techniques to assess the quality of video in the absence of the original reference. To avoid the drawback of existing system such as lossless compression, gray scale mapping and noisy images forces higher bit plane when distortion are easily visible. Data hiding is also used for concealment in applications of video transmission, gray scale mapping and noisy image. Edge quality information and number of bits of a block are hidden in the bit streams processed in an encrypted format to maintain security and privacy.
International Journal of Architectural Heritage: Conservation, Analysis, and Restoration A Force-Based Beam FE for the Pushover Analysis of Masonry Buildings

A simplified approach for analyzing the nonlinear response of masonry buildings, based on the equivalent frame modeling procedure and on the nonlinear equivalent static analyses, is presented. A nonlinear beam finite element is formulated in the framework of a force-based approach, where the stress fields are expanded along the beam local axis, and introduced in a global displacement-based finite element code. In order to model the nonlinear constitutive response of the masonry material, the lumped hinge approach is adopted and both flexural and shear plastic hinges are located at the two end nodes of the beam. A classical elastic-plastic constitutive relationship describes the nonlinear response of the hinges, the evolution of the plastic variables being governed by the Kuhn-Tucker and consistency conditions. An efficient element state determination procedure is implemented, which condenses the local deformation residual into the global residual vector, thus avoiding to perform the inner loops needed for computing the element nonlinear response. The comparison with some relevant experimental and real full-scale masonry walls is presented, obtaining a very good agreement with the available results, both in terms of global pushover curves and damage distributions.
Answering Complex Requests with Automatic Composition of Semantic Web Services

—Today, there is a growing need for user to be able to express, and get answers to more complex requests, those including multiple functionalities, conditions, constraints and objectives. Complex requests including multiple functionalities only can not usually be answered with one single Web service. As multiple services are needed, the problem is then to ﬁnd good combination using the available services. This paper contributes to answering this issue. It focuses on the problem of semantic Web services composition to answer such requests. We propose an automatic composition algorithm designing the answering composition. The algorithm takes into account all suitable composition structures. The set of answering composition is modeled as a graph, which supports the selection of the best composition according to the request constraints and objectives.
07 03 24 3 v 2 1 2 O ct 2 00 7 Viscous hydrodynamics relaxation time from AdS / CFT

We consider an expanding boost-invariant plasma at strong coupling using the AdS/CFT correspondence for N = 4 SYM.We determine the relaxation time in second order viscous hydrodynamics and find that it is around thirty times shorter than weak coupling expectations. We find that the nonsingularity of the dual geometry in the string frame necessitates turning on the dilaton which leads to a nonvanishing expectation value for trF 2 behaving like τ.
pa-Evaluation of a Latex Agglutination Test for Diagnosis of Clostridium d\W\c\\e-Associated Colitis

and live suspensions of three C. difficile isolates with LA(+)/TCA(—) results were tested in a rabbit ileal loop assay. All failed to demonstrate ability to produce an enterotoxin. The authors conclude that the LA method is suitable for rapid screening, but LA(+) results re quire confirmation by testing with other methods. (Key Nine patients had serum HBV-DNA in the absence of HBeAg (four had anti-HBe), and seven of these nine patients had stainable HBcAg in the liver (two did not have staining). None of these patients had hepatic HBcAg in the absence of serum HBV-DNA. When these patients were stratified according to their epidemiologic background, serum HBV-DNA was present in a significantly higher number of male homosexuals than in any other groups. This was unre lated to their status of human immunodeficiency viral serology.
Defining the distinct, intrinsic properties of the novel type I interferon, epsilon.

The type I interferons (IFNs) are a family of cytokines with diverse biological activities including antiviral, and immunoregulatory functions. The discovery of the hormonally regulated, constitutively expressed IFNε has suggested a function for IFNs in reproductive tract homeostasis and protection from infections, but its intrinsic activities are untested. We report here the expression, purification, and functional characterization of murine IFNε (mIFNε). Recombinant mIFNε (rmIFNε) exhibited an α-helical fold characteristic of type I IFNs and bound to IFN alpha/beta receptor 1 (IFNAR1) and IFNAR2, but, unusually, it had a preference for IFNAR1. Nevertheless, rmIFNε induced typical type I IFN signaling activity, including STAT1 phosphorylation and activation of canonical type I IFN signaling reporters, demonstrating that it uses the JAK-STAT signaling pathway. We also found that rmIFNε induces the activation of T, B, and NK cells and exhibits antiviral, antiproliferative, and antibacterial activities typical of type I IFNs, albeit with 100- to 1000-fold reduced potency compared with rmIFNα1 and rmIFNβ. Surprisingly, although the type I IFNs generally do not display cross-species activities, rmIFNε exhibited high antiviral activity on human cells, suppressing HIV replication and inducing the expression of known HIV-restriction factors in human lymphocytes. Our findings define the intrinsic properties of murine IFNε, indicating that it distinctly interacts with IFNAR and elicits pathogen-suppressing activity with a potency enabling host defense, but with limited toxicity, appropriate for a protein expressed constitutively in a sensitive mucosal site, such as the reproductive tract. The type interferons family
Design/methodology/approach – CASE STUDY.

Dominant research streams in healthcare management conclude that knowledge transfer between patient groups is accomplished through instructions and/or socially constructed practices. Underlying these views is the belief that texts and practices carry with them the codes necessary for their own decoding and, therefore, enable an unproblematic knowledge transfer. The analysis focused specifically on the interrelated effects between constituents of a group receiving ongoing healthcare and the relationships to knowledge transfer management, through which, group membership and knowledge exchange was mediated. The research asked if this relationship could be improved from both a personal and organisational perspective, by better understanding of the knowledge transfer mechanisms at work. We argue that because private and cultural models mediate decoding of information into meaningful knowledge, knowledge is created from the unique combination of cognitive dispositions of acumen, memory, creativity, volition, emotion, and socio-cultural interaction. Thus, mechanisms for decision-making affect socio group dynamics and interactions via the healthcare environment, manager or practitioner. This case study adopted a qualitative constructivist methodology and thematic analysis of the output data. A total of 20 (n1=20) main interviews and 10 (n2=10) follow up interviews took place over a two month period. Findings – Findings indicate that for this group of participants, knowledge transfer depended on the assumption of real world values as opposed to determinates of healthcare practitioners. Conclusion – These findings show that in a healthcare or organisational context, different perspectives to knowledge must be comprehensively understood before any technique to reduce transfer abnormalities is introduced within an environment. Originality/value – The objective of the article is intended as a theoretical reflection on the implications of knowledge transfer in an organisational context.
Confounding Equivalence in Causal Inference

The paper provides a simple test for deciding, from a given causal diagram, whether two sets of variables have the same bias-reducing potential under adjustment. The test requires that one of the following two conditions holds: either (1) both sets are admissible (i.e., satisfy the back-door criterion) or (2) the Markov boundaries surrounding the manipulated variable(s) are identical in both sets. Applications to covariate selection and model testing are discussed.
Preemptive-TIPS improves outcome in high-risk variceal bleeding An observational study

Patients admitted with acute variceal bleeding (AVB) and Child Pugh C score (CP-C) or Child Pugh B plus active bleeding at endoscopy (CP-B+AB) are at high risk for treatment failure, rebleeding and mortality. Preemptive TIPS (p-TIPS) has been shown to improve survival in these patients but its use in clinical practice has been challenged and not routinely incorporated. The present study aimed to further validate the role of preemptive TIPS in a large number of high-risk patients. The study followed the Strengthening the Reporting of Observational Studies in Epidemiology (STROBE) guideline for reporting observational studies(17). Data were described as frequencies and percentages, means and standard deviation (SD) or median (interquartile range), as appropriate. Baseline characteristics were compared using the Fisher’s exact test for categorical variables, the t test for Gaussian continuous variables and the Mann-Whitney for ordinal and non-Gaussian continuous variables. Survival was estimated using the cumulative incidence function (CIF) with orthotropic liver transplant (OLT) as a competing risk. The risk (Hazard ratio and 95%CI) of death was evaluated using a competitive risk Cox model. The secondary time to event variables were evaluated likewise, but with both death and OLT as a competing risk. Adjusted models were built using propensity scores (PS, i.e. the predicted probability of p-TIPS or the reason for p-TIPS placement) given a set of baseline covariates. All reported analyses for time to event variables are based on competitive risk models and all the inferential analyses are PS adjusted, or otherwise specified. All the analyses were performed using SAS software (9.2; SAS Institute Inc., Cary, NC) or Statistical Package for Social Sciences (version 19.0; SPSS, Chicago, IL), and a level of significance was established at the two-sided 5% level.