Miracle-dz/UniFAR-FTUs huggingface dataset:
Wind Loads on Transmission Line Structures in Simulated Downbursts

Downbursts pose a recognized threat to transmission line networks in South-east Queensland, and many other regions around the world. However, when assessing the structural adequacy of transmission line structures, design codes assume that an atmospheric boundary layer profile provide the basis of wind loading in the design process. Such assumptions may be leaving transmission networks exposed to an unquantified level of threat to a meteorological event that will likely cause the most severe loading on the structure during its lifetime. An analytical/stochastic method of simulating downburst winds has been used to explore the quasi-static loading conditions that occur during downbursts. These are presented in comparison to several existing transmission tower design codes, and the implications with regard to the structural adequacy of transmission line structures is discussed.
Statistical Analysis for On-Chip Power Grid Networks and Interconnects Considering Process Variation

With the aggressive scaling down of semiconductor VLSI devicesfrom 65nm to 45 nm, 32nm, the process induced variability becomesthe major design concern. The fundamental change in VLSI chipdesign in current and future nodes is that what has been designedwill not agree with the products manufactured due to theuncertainties in the manufacture processes. Even worse, thevariabilities keep growing as the technology scales downcontinually. The process induced variations manifest themselvesfrom wafer to wafer, die-to-die and device to device within a die.Some are systematic variabilities and some are randomvariabilities, which have to leave extra margin for worst case.The Monte Carlo method can come to the rescue by simulating theprobability of the worst case in a random way. However, it is wellknown this approach is very time consuming and forbidding slow. Itis highly desirable to have more efficient statistical modelingand simulation techniques and tools to guide the design in thepresence of uncertainties in the nanometer VLSI regime.In this dissertation, the influence of the variability, such asthreshold voltage variation, interconnect wire height, widthvariation, on the performance of power grid delivery networks andsignal interconnect circuits, are studied. First we develop a newstatistical method, which is based on concept of Hermite polynomialchaos, to analyze power grid voltage drop variations of on-chippower grid networks. The new approach considers both wirevariations and sub-threshold leakage current variations, which aremodeled as lognormal distribution random variables. We alsoconsider spacial correlation of the leakage variables by applyingorthogonal decomposition to map the correlated random variablesinto independent ones before the analysis. Second, we propose amore efficient statistical analysis approach, StoEKS, in which theextended Krylov subspace method is used to speedup the solutionprocedure of the variational circuit equations. By using the modelorder reduction technique, StoEKS partially mitigates circuit-sizeincreasing problem associated with the augmented matrices from theGalerkin-based spectral statistical method. Finally, we propose anefficient method to calculate variational interconnect delay,which is a crucial step in the statistical static timinganalysis(SSTA). We apply Numerical quadrature method based onorthogonal polynomial representation (OPR) of statisticalvariations to derive the non-linear, non-Gaussian analyticinterconnect delay models in terms of the interconnect wire width,height variations. It can take in variational parameters in OPRform and outputs the delays computed in OPR form again, which iscompatible with existing SSTA methods.
AN AMBIGUITY FUNCTION INDEPENDENT OF ASSUMPTIONS ABOUT BANDWIDTH AND CARRIER FREQUENCY

Abstract : With the use of a mean-square difference criterion to distinguish echoes from two targets at different ranges moving with different velocities, an ambiguity function is derived. The concept of a modulated carrier is avoided, and the actual Doppler effect of time compression or expansion is used, rather than the more usual approximation of constant frequency shift. Thus this function can be applied to the very-low-frequency broadband signals sometimes employed in sonar systems. It reduces to the Woodward ambiguity function in the case of two targets of nearly equal velocity, and, in general, in a narrow-band approximation. Some properties of this ambiguity function are discussed.
A Risk Management Model of Urban Areas near Ammunition Storage

Abstract : According to safety standards - buildings, civil facilities and heavily used routes can be located at Inhabited Building Distances (IBD) that are termed only as separation distances. Minor injuries and unstrengthened buildings damage not exceeding five percent of their Reinstatement Value are expected. Indirect consequences of Ammunition and Explosives explosion event are not considered at all in the standards. In contrary, safety demands for cases where explosion of Ammunition or Explosives is initiated or caused by hostile activities must be much greater than IBD. In order to prevent casualties or injuries to the public they should be either protected, or being moved beyond a safety distance, much greater than the IBD. The standards usually take the low marginal probability, i.e. 10-6 per annum, and by that assume that accidental events rarely occur. Risk expectancy gives some legitimacy for these relatively short distances. On the other hand, in a circumstance where the probability of an accidental explosion is greater, and ammunition is located near urban areas, the standards might be risky and inappropriate. A risk management model for the analysis and assessment of risks encompassing physical and economic consequences is proposed. Using DDESB- TP14-SAFER methodologies and knowledge, the model estimates a conversion between protective measures and different ammunition quantities vs. IBD for a given site data. A case study was carried out for a given town and a highway located at a permitted IBD of less than 1,000 meters from all kinds of PES (Potential Explosion Site): open storage or an earth covered magazine which contains 100 tons of Net Explosive Weight of HD (Hazard Division) 1.1.
https://researchopenworld.com/avoid-using-sample-with-more-than-70-blasts-for-hla-typing-to-reduce-erroneous-homozygous-hla-typing-results-by-microbead-assay/#

Background: Loss of heterozygosity (LOH) at the human leukocyte antigen (HLA) region could lead to erroneous homozygous HLA typing results. Materials and methods: We investigated HLA typing on peripheral blood samples derived from a patient with acute myeloid leukemia (AML) at diagnosis and remission by Luminex microbead assay. LOH was analyzed by short tandem repeat (STR) analysis at markers of long arm and short arm of chromosome 6 and single-nucleotide polymorphism (SNP) array analysis. For DNA mixing test to define the detection threshold for heterozygous HLA genotypes, we selected 6 samples of homozygous HLA typing and 6 samples of heterozygous HLA typing. Results: At diagnosis (blasts 77% in peripheral blood), HLA typing revealed A*11, B*15:02/88(B75), C*08:01/08, DRB1*08, DQB1*06. Short tandem repeat (STR) analysis of peripheral blood revealed segmental uniparental disomy (UPD) of chromosome 6 (LOH of marker at 6p22, but no LOH at other markers of short arm and long arm of chromosome 6). Analysis of LOH by single-nucleotide polymorphism (SNP) array analysis demonstrated no copy number variations, but LOH on chromosome 6 [34.6Mb] and on chromosome 13 [92.8Mb]. At remission, HLA typing was A*11, A*24, B*15:02/112(B75), B*40:01/22N (B60), C*07:02/32N, C*08:01/08, DRB1*08, DRB1*14, DQB1*05, DQB1*06. DNA mixing experiments revealed that the minimum threshold for detecting HLA heterozygosity using Luminex technology is < 70% homozygous sample. Conclusion: We describe an erroneous homozygoug HLA typing due to LOH resulting from segmental UPD. We should avoid sampling of blood with more than 70% blasts for HLA typing to reduce erroneous homozygous HLA typing results.
Aerodynamics of Wind Turbines

General Introduction to Wind Turbines * 2-D Aerodynamics * 3-D Aerodynamics * 1-D Momentum Theory for an Ideal Wind Turbine * Shrouded Rotors * The Classical Blade Element Momentum Method * Control/Regulation and Safety Systems * Optimization * Unsteady BEM Method * Introduction to Loads and Structures * Beam Theory for the Wind Turbine Blade * Dynamic Structural Model of a Wind Turbine * Sources of Loads on a Wind Turbine * Wind Simulation * Fatigue * Final Remarks * Index
Safe human-robot interaction based on a hierarchy of bounding volumes

This work was supported in part by the Spanish Ministry of Education under grant AP2005-1458 and by the Spanish Ministry of Science and Innovation under research projects DPI2005-06222 (Design, Implementation and Experimentation of Intelligent Manipulation Scenarios for Automatic Assembly/Disassembly Applications) and DPI2008-02647 (Intelligent Manipulation through Haptic Perception and Visual Servoing by Using and Articulated Structure situated over a Robotic Manipulator).
Keeping Watch! Recounting Twenty-Five Years of the Office of Chief Accountant, U.S. Securities and Exchange Commission, 1976–2001

This article adds to the literature of accounting regulation by providing background, including facts and circumstances relating to a quarter century of SEC activity preceding the events identified with the reshaping of the capital markets following the dot.com collapse and the attack on the World Trade Center, 11 September 2001. The subsequent collapse of Enron, the bankruptcy of Worldcom, the dissolution of Andersen, one of the Big Five accounting firms, and the passage in the United States of the Sarbanes-Oxley Act, collectively have ushered in a new era of public-private capital market relationships. This study provides guidance and outlines topics useful to future researchers undertaking assessments of regulatory policies and the individuals involved in their administration. From 1976 to 2001 five individuals played a significant role in the development of the U.S. Securities and Exchange Commission's disclosure and reporting practices by virtue of their office and the collective influence of their views. A. Clarence Sampson (1976-87), Edmund Coulson (1988-91), Walter P. Schuetze (1992-95), Michael H. Sutton (1995-98) and Lynn E. Turner (1998-2001) directed accounting policy activities at the SEC during these years.
Antiseptic Skin Agents to Prevent Surgical Site Infection After Incisional Surgery

Objective: To compare SSI rates between the skin preparation agents: PI-Aq, povidone-iodine with alcohol (PI-Alc), and chlorhexidine with alcohol (C-Alc). Background: Guidelines suggest that alcohol-containing chlorhexidine solutions are the gold standard for skin preparation before surgery. It remains difficult to determine whether it is the chlorhexidine component or the addition of alcohol that confers the most benefit. Methods: We conducted a multicenter, prospective, combined non-inferiority (PI-Alc vs C-Alc) and superiority (PI-Alc vs PI-Aq) randomized clinical trial. Participants were randomized 1:1:1 to receive either C-Alc, PI-Alc, or PI-Aq. The primary outcome was SSI rate as defined by the Centers for Disease Control. Secondary outcomes were complication rates, length of hospital stay, readmissions, and skin reactions. Results: Between January 2015 and December 2018, 3213 patients were randomized (C-Alc: 1076, PI-Alc: 1075, and PI-Aq: 1062). Mean age of participants was 57% and 55% were female. SSI rates were: C-Alc 11.09%, PI-Alc 10.88%, and PI-Aq 12.56%. PI-Alc was found to be non-inferior to C-Alc (mean difference, −0.21%; 95% confidence interval, −2.85 to 2.44; P = 0.0009 non-inferiority), whereas PI-Alc was not superior to PI-Aq (mean difference, −1.68%; 95% confidence interval, −4.40 to 1.05; P = 0.2302). There were no differences seen in secondary outcomes between groups and no treatment related adverse events or deaths occurred. Conclusions: PI-Alc is non-inferior to C-Alc and not superior to PI-Aq. This is at odds with current guidelines that suggest alcohol-based chlorhexidine solutions should routinely be used for surgical skin preparation. Trial Registration: Australia and New Zealand Clinical Trials Registry: ANZCTRN12615000021571. www.anzctr. org.au
Mothering and Stress during COVID-19: Exploring the Moderating Effects of Employment

Using primary data from the Assessing the Social Consequences of COVID-19 study, the authors examined how the pandemic affected the stress levels of women with and without coresiding minor children (mothers vs. nonmothers), paying special attention to the moderating role of employment status. The ordinary least squares regression results show that following the pandemic outbreak, among full-time working women, mothers reported smaller stress increases than nonmothers. In contrast, among part-time and nonemployed women, mothers and nonmothers experienced similar stress increases. Also, full-time working mothers reported smaller stress increases than women with most other mothering and employment statuses. Changes in women’s employment status, following pandemic onset, had limited impacts on the patterns of stress change. This study contributes to research on parenting and health by showing that during times of crisis, full-time employment may be protective of mothers’ mental health but may not buffer the mental health deterioration of women not raising children.
Discovery of Fungal Metabolites Bergenin, Quercitrin and Dihydroartemisinin as Potential Inhibitors Against Main Protease of SARS-CoV-2

Emergence of severe acute respiratory syndrome corona virus 2 (SARS-CoV-2) infection has given rise to COVID-19 pandemic, that is wreaking havoc worldwide. Therefore, there is an urgent need to find out novel drugs to combat SARS-CoV-2 infection. In this backdrop, the present study was aimed to assess potent bioactive compounds from different fungi as potential inhibitors of SARS-CoV-2 main protease (Mpro) using an in-silico analysis. Nearly 118 bioactive compounds were extracted from Dictyophora indusiata, Geassstrum triplex and Cyathus stercoreus and identified using HR LC/MS analysis. Of which, only bergenin (D. indusiata), quercitrin (G. triplex) and dihydroartemisinin (C. stercoreus) were selected based on their medicinal uses, binding score and active site covered. The 6LU7, a protein crystallographic structure of SARS-CoV-2 Mpro, was docked with bergenin, quercitrin and dihydroartemisinin using Autodock 4.2 and the binding energies obtained were -7.86, -10.29 and -7.20 kcal/mol, respectively. Bergenin, quercitrin and dihydroartemisinin formed hydrogen bond, electrostatic interactions and hydrophobic interactions with foremost active site amino acids THR190, GLU166, GLN189, GLY143, HIS163, HIS164, CYS145 and PHE140. Present investigation suggests that these three drugs may be used as alternative inhibitors against SARS-CoV-2 Mpro. However, further research is necessary to assess in vitro potential of these drugs. To the best of our knowledge, present investigation reported these three bioactive compounds of fungal origin for the first time.
Reliable voltage monitoring system for synchronization of distributed power generation systems to utility grid

The unceasing progression of DPGS (Distributed Power Generation Systems) gives an effective and inexpensive approach, for electricity generation near by the consumer. Though for better performance, the distributed power generating stations are being allied to the utility network, there is an emergent necessity for the DPGS to work properly and uninterruptedly in case small grid instabilities. This needs developments to be made forthe control arrangement of DPGSs at the grid-side converter. As a consequence, grid interlinking necessities applied to distributed generations, are need to be continuously updated for maintaining the stability and the quality of the grid voltage. In the realm of grid interconnection, grid synchronization system is the main part of the control scheme of grid connected inverter. This is liable for extracting the phase angle of the grid voltage. One best technique, which is used today are phase-locked loops. From the beginning of the thesis a brief introduction about the distributed power generating stations is given. Later, voltage monitoring systems based on zero crossing detection (ZCD) to Phase Locked Loop (PLL) are given.A comprehensive survey aboutquadrature-signal generation, which is essential for three-phase and single-phase phase-locked-loop, is given. These QSG techniques are investigated and simulated in MATLAB-2010. Finally, thesis covers an advance synchronization approach in both three-phase and single-phasePLL with the inclusion of Second Order Generalized Integrator (SOGI). Both PLLs are experimentally verified by the use of LABVIEW-2010 with coalition with NI USB 6341
Sensorimotor Synchronization - Modeling human response to step changes: Using continuous transfer functions

The purpose of this thesis is to explore the possibility of continuous modeling of rhythm production. To do this it is assumed that the irregular time intervals of rhythm production can be regarded as irregular samples of a continuous process. Based on several preliminary experiments, system identification theory and previous research an experiment with step changes and ramps is conducted. Making use of averaging the noise observed in the preliminary experiments is reduced. A persistent overshoot is observed for the step changes and it is decided to evaluate only four transfer function models. The second order underdamped transfer function model with a zero and a time delay shows the best performance. Using different sets of data for validation and for estimation reveals only partial success of the model. The model ultimately fails the validation test and is thus discarded for the purpose of this thesis. Within the work with this thesis it is also found that clapping shows lower variability than finger tapping, which is explained by a slower error correction process. The overshoot observed in the step changes is attributed to the necessity of keeping phase relation and not because of an initial over estimation of the new rhythm.
Optimal Size & Location of Distributed Generation using Bird Swarm Optimization with Cuckoo Search Sorting Algorithm

In this paper a natural habitat inspired metaheuristic Bird Swarm Optimization algorithm is implemented with improvisations made for the development of solution for the optimal allocations and optimal size prediction problem of Dispersed generation/ Distributed Generator in a radial power system distribution system in consideration of the drawbacks in the previous algorithms both in the context of convergence time and the optimal sizing with respect to the cost analysis for operation of the system with different number of DG’s installed in such a way that the optimal locations and sizes of DG’s installed is finalised with highest priority to the economical operation along with the immediate priority given to the network losses along with voltage deviations. To avoid the draw backs in previous optimisation algorithm regarding accuracy and run time. Along with the Cognitive component Weighted factor Bird Swarm optimisation (CWFBSO) algorithm a new concept is introduced called DG Size tuner Such that cost effective economical installation is possible as by the size tuner it is possible to compare the losses and voltage profile within the mean difference of the optimal sizes of final allocation determined by the main algorithm i.e., CWFBSO. Obtained results using CWFBSO in determining optimal locations and sizes of DG’s is capable showing good performance with less run time and convergence time and by using size tuner the optimal size selected economically with respect to less voltage deviation and minimal losses.
Stage 1

Clan Characters: Trueborn characters must begin Stage 1 in a Clan Crèche. Freeborn characters start the Life Path based on their caste: scientist and merchant caste characters start on the White Collar Path, technician caste on Blue Collar, laborer caste on Blue Collar or Farm (player's choice), and dark caste on the Back Woods, Farm, Street or Blue Collar paths. If you want your character to be a freeborn warrior, he or she must begin the Life Path in one of the civilian castes.
Design of VCOs in Deep Sub-micron Technologies

Design of VCOs in Deep Sub-micron Technologies Evan Kjell Jorgensen Supervising Professor: Dr. P. R. Mukund This work will present a more accurate frequency prediction model for single-ended ring oscillators (ROs), a case-study comparing different ROs, and a design method for LC voltage-controlled oscillators (LCVCOs) that uses a MATLAB script based on analytical equations to output a graphical design space showing performance characteristics as a function of design parameters. Using this method, design trade-offs become clear, and the designer can choose which performance characteristics to optimize. These methods were used to design various topologies of ring oscillators and LCVCOs in the GlobalFoundries 28 nm HPP CMOS technology, comparing the performance between different topologies based on simulation results. The results from the MATLAB design script were compared to simulation results as well to show the effectiveness of the design methods. Three varieties of 5 GHz voltage controlled ring oscillators were designed in the GlobalFoundries 28 nm HPP CMOS technology. The first is a low current low dropout regulator (LDO) tuned ring oscillator designed with thin oxide devices and a 0.85 V supply. The second is a high current LDO-tuned ring oscillator designed with medium oxide devices and
Cell Morphology-Guided De Novo Hit Design by Conditioning Generative Adversarial Networks on Phenotypic Image Features

Developing new small molecules that are bioactive is time-consuming, costly and rarely successful. As a mitigation strategy, we apply, for the first time, generative adversarial networks to de novo design of small molecules using a phenotype-based drug discovery approach. We trained our model on a set of 30,000 compounds and their respective morphological profiles extracted from high content images; no target information was used to train the model. Using this approach, we were able to automatically design agonist-like compounds of different molecular targets.