Miracle-dz/UniFAR-FTUs huggingface dataset:
Near-duplicate web page detection: A comparative study of two contrary approaches

Detection of duplicate and near-duplicate web pages has attracted voluminous research among the web crawling research community. There have been a considerable number of significant researches available in the literature for near-duplicate detection, but, none has been accepted as a universal solution. G.S. Manku et al.'s fingerprint based approach proposed in 2007 was considered as one of the “state-of-the-art" algorithms for finding near-duplicate web pages. In our earlier work, we had devised an efficient similarity score based approach for near-duplicate web page detection. The experimentation on the proposed approach has showed that it has achieved almost detection accuracy identical to G.S. Manku et al.'s fingerprint based approach. Hence, in this paper, we conduct an extensive comparative study between our similarity score based approach and G.S. Manku et al.'s fingerprint based approach in terms of the computational factors namely: 1) Time and 2) Storage space. The performances of the two approaches were considered to be ideally the same, and so, we take up complexity measures namely time and memory space to determine the better approach of the two. The comparison study clearly portrays the better (less complex) of the two approaches based on the factors considered.
A Novel Directly Compressible Co-Processed Excipient for Sustained Release Formulation

Article history: Received on: 24/08/2013 Revised on: 10/09/2013 Accepted on: 22/09/2013 Available online: 30/09/2013 A novel directly compressible (DC) co-processed excipient with improved functionality and masking the undesirable properties of individual excipients was developed without any chemical modification by using simple laboratory technique. For the development of co-processed excipient, release retarding polymers such as Polyethylene oxide (Polyox WSR 301) and hydroxyl propyl methyl cellulose (Methocel K4M) were used. Co-processed excipient was prepared in polymers weight ratio of 1:9 to 9:1 by roller compaction technique. Co-processed excipient prepared from polymers ratio of 7:3 and 8:2 showed good physico-chemical properties. The developed DC grade co-processed excipient was characterized for DSC, FTIR, SEM, XRD which confirms the absence of any chemical changes during co-processing. Highly water soluble Metoprolol succinate and poorly water soluble anhydrous Theophylline was used as model drugs for Invitro release study. Formulations prepared using co-processed excipient showed sustain drug release in which initial burst release was controlled by polyethylene oxide and HPMC controls the extended drug release. Developed formulations were kept for stability study for three month as per ICH guidelines and found to be stable. Study indicates that use co-processed excipient has added advantage over polymer with single property and can be used in sustain release formulation irrespective of drug type.
Factors Influencing the Enhancement of the Infectivity of Poliovirus Ribonucleic Acid by Diethylaminoethyl-Dextran

The enhancement by diethylaminoethyl-dextran (DEAE-D) of the infectivity of poliovirus ribonucleic acid (RNA) for cell cultures was demonstrated by infective-center as well as by plaque assays, both in nonprimate (L) and primate cell systems (MK, HeLa, LLC-MK2). The sensitivity of plaque assays was greatly improved by using a tris (hydroxymethyl)aminomethane-buffered synthetic medium (basal medium Eagle) and freshly confluent cell monolayers. Enhancement of nucleic acid infectivity was directly dependent on the molecular weight of the DEAE-D. Two observations bearing on the action of DEAE-D appeared important: ribonuclease activity was reduced by DEAE-D, and cells pretreated with DEAE-D remained susceptible to infection with RNA in isotonic medium. Appreciable susceptibility of the treated cells persisted for at least 2 hr; the susceptible state could be reversed at will by an application of heparin. Enhancement of nucleic acid infectivity was independent of an effect of DEAE-D on intact virus and agar inhibitors.
SLAM for robot navigation

Simultaneous localization and mapping (SLAM) for the mobile robot navigation has two main problems. The first problem is the computational complexity due to the growing state vector with the added landmark in the environment. The second problem is the data association which matches the observations and landmarks in the state vector. In this study, we compare the extended Kalman filter-(EKF)-based SLAM which is well-developed and well-known algorithm, and the compressed extended Kalman filter-(CEKF)-based SLAM developed for decreasing the computational complexity of the EKF-based SLAM. We describe two simulation programs to investigate these techniques. The first program is written for the comparison of EKF- and CEKF-based SLAMS according to the computational complexity and covariance matrix error with the different numbers of landmarks. In the second program, EKF- and CEKF-based SLAM with the ICNN and JCBB data association algorithms simulations are presented. For this simulation, the differential drive vehicle that moves in a 10 m square trajectory and LMS 200 2-D laser range finder are modelled and landmarks are randomly scattered in that 10 m square environment.
House Sparrows Do Not Constitute a Significant Salmonella Typhimurium Reservoir across Urban Gradients in Flanders, Belgium

In recent decades major declines in urban house sparrow (Passer domesticus) populations have been observed in north-western European cities, whereas suburban and rural house sparrow populations have remained relatively stable or are recovering from previous declines. Differential exposure to avian pathogens known to cause epidemics in house sparrows may in part explain this spatial pattern of declines. Here we investigate the potential effect of urbanization on the development of a bacterial pathogen reservoir in free-ranging house sparrows. This was achieved by comparing the prevalence of Salmonella enterica subspecies enterica serotype Typhimurium in 364 apparently healthy house sparrows captured in urban, suburban and rural regions across Flanders, Belgium between September 2013 and March 2014. In addition 12 dead birds, received from bird rescue centers, were necropsied. The apparent absence of Salmonella Typhimurium in fecal samples of healthy birds, and the identification of only one house sparrow seropositive for Salmonella spp. , suggests that during the winter of 2013–2014 these birds did not represent any considerable Salmonella Typhimurium reservoir in Belgium and thus may be considered naïve hosts, susceptible to clinical infection. This susceptibility is demonstrated by the isolation of two different Salmonella Typhimurium strains from two of the deceased house sparrows: one DT99, typically associated with disease in pigeons, and one DT195, previously associated with a passerine decline. The apparent absence (prevalence: <1.3%) of a reservoir in healthy house sparrows and the association of infection with clinical disease suggests that the impact of Salmonella Typhimurium on house sparrows is largely driven by the risk of exogenous exposure to pathogenic Salmonella Typhimurium strains. However, no inference could be made on a causal relationship between Salmonella infection and the observed house sparrow population declines.
Design of a compact tuned antenna system for mobile MIMO applications

A small tuneable MIMO antenna module is investigated for possible UMTS mobile applications. The radiators are realized as slotted planar monopoles. The two-element MIMO antenna module occupies a volume of 50.0 × 37. 5 × 1.6 mm3, and is printed onto a FR4 substrate. Low mutual coupling between the radiators is achieved by means of the addition of a coupling strip to a defected ground plane structure. The effect of tuning the resonant frequency, as well as the operational bandwidth is investigated in simulation which indicates that this antenna system should provide a mutual coupling across the full bandwidth better than -13dB.
Prognostic factors for survival in colorectal cancer patients.

OBJECTIVE To determine the prognostic value for survival of pretreatment characteristics and treatments in stage 1-IV colorectal cancer (CRC) patients. MATERIAL AND METHOD The present retrospective cohort study was conducted by reviewing 287files of stage I-IV CRC patients. Fifteen clinical variables were investigated through analysis as prognostic factors for survival. RESULTS The median survival time for CRC patients, colon and rectal cancer patients were 37.2, 43.2, and 29.5 months respectively The 5-year survival rates of CRC patients were 38.6%. 5-year stage-specific survivals for stage I, II, III and IV CRC were 100%, 68%, 44%, and 2% respectively (p < 0.001). Sixty eight percent of CRC patients were in stages III and IV Multivariate analysis revealed age > or =60 years old, WHO performance status 3, stage III and IV disease and poorly differentiated histology as poor prognostic factors for survival, whereas treatment with complete surgical resection and adjuvant chemotherapy was a good prognostic factor for survival in CRC. CONCLUSION As the majority of patients were in advanced stages with poor prognosis, early stage disease identification and treatment with newer agents would likely improve survival of high-risk CRC patients.
Combined Zernike Moment and Multiscale Analysis for Tamper Detection in Digital Images

The paper proposes a new approach as a combination of the multiscale analysis and the Zernike moment based for detecting tampered image with the formation of copy – move forgeries. Although the traditional Zernike moment based technique has proved its ability to detect image forgeries in block based method, it causes large computational cost. In order to overcome the weakness of the Zernike moment, a combination of multiscale and Zernike moments is applied. In this paper, the wavelets and curvelets are candidates for multiscale role in the proposed method. The Wavelet transform has successful in balancing the running time and precision while the precision of the algorithm applied the Curvelets does not meet the expectation. The comparison and evaluation of the performance between the Curvelets analysis and the Wavelets analysis combining with the Zernike moments in a block based forgery detection technique not only prove the effective of the combination of feature extraction and multiscale but also confirm Wavelets to be the best multiscale candidate in copy-move detection.
Model of Attention Deficit Hyperactivity Disorder: Five‐Trial, Repeated Acquisition Inhibitory Avoidance in Spontaneously Hypertensive Rat Pups

There is no one definitive animal model or test for ADHD. However, behavioral symptoms of this disorder, such as inattentiveness, impulsivity, rate of learning, and hyperactivity, can be evaluated in animals. Unfortunately, many of the cognitive tests used to assess attention and impulsivity require considerable equipment, and financial and time resources. Additionally, many of the genetic animal models are difficult to obtain due to cost, intellectual property issues, or difficulties in breeding sufficient numbers. The spontaneously hypertensive rat (SHR) is relatively easily obtained and exhibits many behavioral abnormalities analogous to those observed in ADHD. This unit describes a cost‐effective and relatively simple approach to modeling ADHD preclinically, by training juvenile SHR pups in a five‐trial repeated acquisition inhibitory avoidance model with components of attention and response inhibition. The model is suited to identifying compounds with stimulant and nonstimulant mechanisms of action, although the latter has yet to be verified conclusively in the clinic.
From primordial germ cell to primordial follicle: mammalian female germ cell development

In mammals, the final number of oocytes available for reproduction of the next generation is defined at birth. Establishment of this oocyte pool is essential for fertility. Mammalian primordial germ cells form and migrate to the gonad during embryonic development. After arriving at the gonad, the germ cells are called oogonia and develop in clusters of cells called germ line cysts or oocyte nests. Subsequently, the oogonia enter meiosis and become oocytes. The oocyte nests break apart into individual cells and become packaged into primordial follicles. During this time, only a subset of oocytes ultimately survive and the remaining immature eggs die by programmed cell death. This phase of oocyte differentiation is poorly understood but molecules and mechanisms that regulate oocyte development are beginning to be identified. This review focuses on these early stages of female germ cell development. genesis 44:622–632, 2006. © 2006 Wiley‐Liss, Inc.
Expression of therapeutic levels of factor VIII in hemophilia A mice using a novel adeno/adeno-associated hybrid virus

Summary We have generated an E1a/E1b/E3-deleted adeno/adeno-associated (Ad/AAV) hybrid virus driven by a small nuclear RNA (pHU1-1) promoter for expression of a B domain-deleted (Thr761-Asn1639) factor VIII transgene (FVIIIΔ761-1639). Productive replication of Ad/AAV/FVIIIΔ761-1639 in AAV repexpressing cells resulted in generation of monomeric and dimeric mini-adenoviral (mAd) replicative forms that retained the AAV integration elements (mAd/FVIIIΔ761-1639). In vitro studies using Ad/AAV/FVIIIΔ761-1639 generated ∼2-logs greater FVIII activity than mAd/FVIIIΔ761-1639. To determine its capacity for in vivo excision and/or genomic integration, Ad/AAV/FVIIIΔ761-1639 was injected by tail vein into three groups of hemophilia A mice (2 X 1011 vp [n = 3]; 4 X 1011 vp [n = 3]; 8 X 1011 vp [n = 3]), with clear concentration-dependent increase in FVIII activity (range 160-510 mU/ml; plasma activity 16% – 51% of normal). Peak activity was seen by Day (D) 5, with slow return to baseline by D28 (0.1 – 0.9% activity); in only 3/9 mice was loss of FVIII activity associated with development of anti-FVIII antibodies. Quantitative-PCR using genomic DNA isolated from D28 liver, spleen, heart, lungs, and kidney demonstrated the highest concentration in liver (∼10 genomes/ cell), with little to no organ toxicity at early (D5 or 6) or late (D28) post-infusion time points. There was no evidence for spontaneous transgene excision or genomic integration in vivo as evaluated by quantitative PCR and genomic blotting. These data establish (i) the feasibility and applicability of developing high-titer Ad/AAV hybrid viruses for FVIII delivery using a small cellular promoter, (ii) the potential utility of this virus for generation of “gutted” monomeric and dimeric mAD/FVIII retaining AAV integration elements, and (iii) that the development of strategies for regulated Rep68/78 co-expression may provide a novel approach for excision, integration, and long-term FVIII transgene expression.
How Family, Community, and Work Structured High Blood Pressure Accounts

High blood pressure is one of the most often researched, yet least understood health disparities among African Americans. This descriptive, critical discourse analysis examined how family and community demographics and paid and unpaid work structured participants' accounts of high blood pressure experiences in Washington State. Thirty-seven urban-dwelling African American women (n = 17) and men (n = 20) in Washington State enrolled in the study from 2000-2001. Reports about stress, concerns, worry, loneliness, and paid and unpaid work were given in semi-structured interviews. Analysis results are embedded within three major themes: (a) Aware, But Not Informed, (b) Negotiating Self, Kin and Community Health, and (c) Distant Lives, Distant Love. Knowledge of life factors influencing African Americans' high blood pressure appraisals will help develop context-specific health programs focused on their concerns.
Analysis of multidrug‐resistance (MDR‐1) glycoprotein and CD56 expression to separate monoclonal gammopathy from multiple myeloma

Summary Monoclonal gammopathy of undetermined significance (MGUS) is different from multiple myeloma (MM) by a low proliferation and by its indolent clinical course. In this study, two biological parameters were investigated which mark the transition from MGUS to MM, i.e. expression of the P‐170 glycoprotein associated with the multidrug resistance phenotype (MDR‐1) and expression of the natural killer cell antigen, CD56. Strong MDR‐1 expression was found in plasma cells of 32/38 untreated MGUS as compared with 33/105 untreated MM stage I–III (84%v 32%, P<0.001) and in 0/10 normal plasma cell samples. CD56 expression in high density was present in 43/57 analysed untreated MM but in none of 23 MGUS (78%v 0%P<0.0001). Plasma cells did characteristically show a low Ki‐67 proliferation index in 14/15 MGUS patients (mean 0.05%, range 0–0.2%) and a higher index in 25 analysed MM patients (mean 2.31%, range 1–7%, P<0.03).
Numerical simulation of heat transfer and fluid flow in coaxial laser cladding process for direct metal deposition

The coaxial laser cladding process is the heart of direct metal deposition (DMD). Rapid materials processing, such as DMD, is steadily becoming a tool for synthesis of materials, as well as rapid manufacturing. Mathematical models to develop the fundamental understanding of the physical phenomena associated with the coaxial laser cladding process are essential to further develop the science base. A three-dimensional transient model was developed for a coaxial powder injection laser cladding process. Physical phenomena including heat transfer, melting and solidification phase changes, mass addition, and fluid flow in the melt pool, were modeled in a self-consistent manner. Interactions between the laser beam and the coaxial powder flow, including the attenuation of beam intensity and temperature rise of powder particles before reaching the melt pool were modeled with a simple heat balance equation. The level-set method was implemented to track the free surface movement of the melt pool, in a continuous las.
Diversity of bacteria and Archaea in sulphate-reducing enrichment cultures inoculated from serial dilution of Zostera noltii rhizosphere samples.

We have analysed the diversity of culturable sulphate-reducing bacteria (SRB) in Zostera noltii colonized sediments from Bassin d'Arcachon (France). Four organic substrates have been tested as well as the combination of H2 and CO2 to select for lithotrophic SRB. All energy sources were supplied in parallel cultures that were amended with yeast extract plus NH4+ and prepared without a source of combined nitrogen, the latter to select for diazotrophic SRB. The 10 different enrichment media were inoculated from serial dilution of rhizosphere samples. The highest dilution cultures yielding positive growth (i.e. 10-7) were studied by molecular techniques (16S rDNA clone libraries, RISA and ARDRA). Lactate as a single organic substrate in combination with a source of combined nitrogen resulted in selection of members of the Desulfovibrionaceae. Surprisingly, when lactate was added without a source of combined nitrogen, Desulfobacteriaceae were selected. A strong influence of the presence or absence of combined nitrogen was also observed for the substrates sucrose and fructose. Whereas the liquid culture growing on sucrose and NH4+ systematically yielded 16S rDNA clones related to an environmental unidentified green sulphur bacterium (OPS185), on plates we were able to isolate a SRB related to Desulfovibrio dechloracetivorans, which likely represents a non-described species. Under diazotrophic conditions, sucrose selected for SRB clones related to the cluster formed by Desulfovibrio zosterae, Desulfovibrio salexigens and Desulfovibrio bastinii. The corresponding isolate obtained on plates showed only low sequence similarity with this closest neighbour (93.8%), and we suggest that it also represents a non-described species. Surprisingly, a 16S rDNA sequence corresponding to an archaeon, i.e. a non-extremophile Crenoarchaeota, was retrieved from several of the SRB enrichment cultures even after subsequent transfers.
A Culture in Transition: Paramedic Experiences with Community Referral Programs.

OBJECTIVES As an aging population continues to place strain on the health care system, many older adults are living with unmet social and medical needs. In response, Emergency Medical Services (EMS) have initiated programs that encourage paramedics to refer patients in need to community based support services. This qualitative study explores frontline paramedic experiences with referral programs to identify opportunities and challenges in their practice. METHODS This study used an intepretivist qualitative study design involving interviews of frontline paramedics employed in a region where referral programs were in place. Interviews were semi-structured and one-on-one. Data were transcribed verbatim and analyzed using inductive open coding throughout, then grouped to identify themes. Data collection and analysis were conducted simultaneously and flexibly until saturation. RESULTS Twenty-three interviews were conducted representing 6 regions. When participating with referral programs the data revealed that frontline paramedics appear to experience (a) role confusion, (b) an inadequate knowledge base, (c) inadequate feedback, (d) undefined accountability, and (e) strong patient advocacy. CONCLUSIONS In a strained health care system, EMS and paramedics have an opportunity to better serve patients by initiating referrals for patients they encounter with unmet social and medical needs. However, referral programs face a number of challenges that, if left poorly addressed, may threaten the success of such programs.
APPLICATION OF BRIGGS-RAUSCHER REACTION FOR MEASUREMENT OF ANTIOXIDANT CAPACITY OF CROATIAN WINES

Briggs-Rauscher (BR) reaction is one of the most co mm nly studied oscillation reactions which has been applied for measurement of antioxidant activity of water-soluble substances. By addition of free radic als (from fruits or vegetables), there is an immediate quenching of oscillations. The reaction is followed potentiometrically and the inhibition time (IT), or time of no oscillations, is proportional to concen tration of antioxidant. pH of BR reaction is about 2, what is similar to th at of the fluids of the main digestive process (human stomach), giving in vitro information’s on a tioxidant activity at “real digestion conditions” and can help in assessment of nutrition for maintenance of health and prevention of diseases. Antioxidant activities of different concentrations of native Croatian red and white wines are analysed by inhibition of BR reaction and determina tion of total phenols using galic acid as the calib r tion standard. By use of mathematical models, relative antioxidant activities of antioxidants and amounts of total phenols are estimated. Second order polynomial cali bration curve is estimated in the range of 150-2500 galic acid equivalent (GAE mg l ), with standard error of 84 GAE mg l .