Miracle-dz/UniFAR-FTUs huggingface dataset:
Electroanalysis of Mefenamic Acid in Pharmaceutical Formulation and Spiked Biological Fluids on Modified Carbon Nanotube Electrode

The development of an electrochemical sensor for determination of mefenamic acid is the main purpose of this work. The determination was performed in pharmaceutical formulations, spiked urine and human plasma samples by multi-walled carbon nanotube-graphite/Ag (MWCNTs-G/Ag) electrode. Hence some voltammetric methods were investigated to determination of mefenamic acid. The dependence of peak currents and potentials on pH and voltammetric parameters was investigated for the optimization of electrochemical method. The porous structure of MWCNTs-graphite mixture improves the electroactive surface area. As a result, a remarkable increasing in the peak currents was observed. The prepared mixture displayed an electrocatalytic effect in anodic oxidation of mefenamic acid with a sensitivity augmentation. The best electrochemical response was obtained from square wave voltammetry with a sensitive peak at 0.68 V in pH 5. The prepared electrode showed good standard calibration curves during 3 days over a wide concentration range with RSD values ranging from 1.6-8%. The limits of quantification and detection were 50 and 16 ng/mL, respectively.
VASCULAR AND OTHER EMERGENCIES IN THE HEAD

Imaging provides crucial information regarding emergent orbital abnormalities, and the radiologist fulfills an important role in guiding patient care and contributing to favorable outcomes. Knowledge of the imaging features of nontraumatic orbital conditions commonly seen in the emergent setting—infections, inflammation, vascular abnormalities, and retinal and choroidal detachments—is necessary to achieve a prompt and accurate diagnosis, thereby avoiding permanent vision loss and other potentially devastating consequences. The ability to distinguish these entities from physiologic calcifications, posttherapeutic changes, and orbital devices allows optimal management without unnecessary further diagnostic work-up. For orbital imaging in the acute setting, computed tomography is the first-line modality, with magnetic resonance imaging playing an important secondary role.
Relationship between growth of Nitraria schoberi and some soil properties.

A study was carried out to investigate the relationship between growth of Nitraria schoberi and some soil properties in Segzi plain in the eastern of Isfahan province (center of Iran). Due to its special geographic condition, Iran is a dry and semidry zone of the world. Nitraria schoberi is a drought-resistant shrub plants. In the study area, Nitraria schoberi plants were all of similar age. A total of 6 profiles were studied and from each profile depth (0-30, 30-60 and 60-90 cm), sampling was conducted. For each soil sample obtained, electrical conductivity (EC), sodium ions (Na), bicarbonate (HCO3) and the percentage of gypsum, calcium carbonate and clay were measured. Plant physiological parameters including plant height and top were measured. The data thus obtained were analysed through the SPSS software. The results indicated that the electrical conductivity, sodium ions, HCO3 and the percentage of clay had negative effects on plant physiologic parameters whilst the percentage of calcium carbonate had a positive effect on plant physiologic parameters. However, the percentage of gypsum did not have any significant effect on the plant physiologic parameters.
National Convention of the Association for Educational Communications and Technology

This paper reports on the development, design, and initial field testing of a narrative simulation, "'This Just Is! ' Jeff's Story," that focused on homophobia and adolescent suicide. The initial field test was conducted with two user groups--a graduate class of professionals in the field of higher education student development, and a small group of ministers certified as pastoral counselors. The evaluation utilizes data obtained through expert feedback, exercise field tests, individual and focus group interviews, and observation, as a basis for informing continued development of this design. Formative evaluation results are summarized in the following areas: usability; veracity; the extent to which the user felt the experience was informative; cognitive, or the extent to which the exercise provoked thinking; affective, or impact on attitude; and the value of group discussion in the exercise process. Desired learning outcomes that focus on attitudes, beliefs, and biases may lend themselves to further evaluation of narrative simulation in creating contexts in which to examine deeply held beliefs. (Contains 40 references.) (MES) Reproductions supplied by EDRS are the best that can be made from the original document. Evaluating Narrative Simulation as Instructional Design for Potential to Impact Bias and Discrimination U.S. DEPARTMENT OF EDUCATION Office of Educational Research and Improvement EDUCATIONAL RESOURCES INFORMATION CENTER (ERIC) 13 This document has been reproduced as received from the person or organization originating it. O Minor changes have been made to improve reproduction quality. Points of view or opinions stated in this document do not necessarily represent official OERI position or policy. By: PERMISSION TO REPRODUCE AND DISSEMINATE THIS MATERIAL HAS BEEN GRANTED BY
Teleocortin : A novel member of the corticotropin-releasing hormone family in teleost fish

The corticotropin-releasing hormone (CRH) family of neuropeptides, including CRH and urocortins, plays pivotal roles in the regulation of physiological and behavioral stress responses in vertebrates. In this study, we identified a previously undescribed member of the CRH family of peptides in a teleost fish species (medaka; Oryzias latipes) and named this peptide teleocortin (Tcn). Medaka Tcn is a 41-amino acid polypeptide derived from the C terminus of a larger precursor protein that is encoded by a two-exon gene, thus sharing common structural features with known CRH family peptides. tcn was found exclusively in teleost fish. Phylogenetic analysis suggested that tcn probably has an ancient origin, but was lost from the tetrapod lineage shortly after the divergence of the teleost and tetrapod lineages. In the medaka brain, tcn was expressed in nuclei of the telencephalon, preoptic area, hypothalamus, tegmentum, and isthmic region. As none of these nuclei have been implicated in the control of adrenocorticotropic hormone secretion from the pituitary, Tcn may exert its effects centrally in the brain rather than via stimulation of the pituitary-adrenal/ interrenal axis. Most, if not all, tcn-expressing neurons also expressed crh, suggesting that Tcn and Crh share common physiological functions. Moreover, Tcn activated Crh receptors 1 and 2 with equivalent or slightly higher potency than Crh, further suggesting that these peptides share common functions. Taken together, these data identified Tcn as a novel, teleost-specific member of the CRH family of peptides that may act centrally with Crh to regulate physiological and behavioral stress responses.
Glass Ceiling Effect and Earnings – The Gender Pay Gap in Managerial Positions in German y 201 SOEPpapers on Multidisciplinary

Although there are a variety of studies on the gender pay gap, only a few relate to managerial positions. The present study attempts to fill this gap. Managers in private companies in Germany are a highly selective group of women and men, who differ only marginally in their human capital endowments. The Oaxaca/Blinder decomposition shows that the gender pay gap in the gross monthly salary can hardly be explained using the human capital approach. Adding variables on gender-specific labor market segregation and dimensions of the household and family to the model allows more than two-thirds of the gender pay gap to be explained. However, taking selection effects in a managerial position into account (Heckman correction), the proportion explained decreases to only one-third. This reveals the real extent to which women are disadvantaged on the labor market. In addition, we observe not only that the wages in typical women’s jobs are lower than in typical men’s jobs but also that women are paid less than men in typical women’s jobs. The two-thirds of the gender pay gap that remain unexplained represent the unobserved heterogeneity. This includes, for example, general societal and cultural conditions as well as structures and practices on the labor market and in companies that subject women to pay discrimination and pose an obstacle to them breaking the glass ceiling. JEL Classification: J31, J16, J24
Viral Replication Affect the Errors Made in a Single Cycle of Mutations in HIV-1 Reverse Transcriptase

The genetic variation in HIV-1 in patients is due to the high rate of viral replication, the high viral load, and the errors made during viral replication. Some of the mutations in reverse transcriptase (RT) that alter the deoxynucleoside triphosphate (dNTP)binding pocket, including those that confer resistance to nucleoside/nucleotide analogs, affect dNTP selection during replication. The effects of mutations in RT on the spectrum (nature, position, and frequency) of errors made in vivo are poorly understood. We previously determined the mutation rate and the frequency of different types of mutations and identified hot spots for mutations in a lacZ (the complementing region of lacZ) reporter gene carried by an HIV-1 vector that replicates using wild-type RT. We show here that four mutations (Y115F, M184V, M184I, and Q151M) in the dNTP-binding pocket of RT that had relatively small effects on the overall HIV-1 mutation rate (less than 3-fold compared to the wild type) significantly increased mutations at some specific positions in the lacZ reporter gene. We also show that changes in a sequence that flanks the reporter gene can affect the mutations that arise in the reporter. These data show that changes either in HIV-1 RT or in the sequence of the nucleic acid template can affect the spectrum of mutations made during viral replication. This could, by implication, affect the generation of drug-resistant mutants and immunological-escape mutants in patients.
Fibronectin via Integrin and Decreases Attachment to In vivo Tumorigenicity Gene Expression Abolishes Ovarian Cancer

The WW domain–containing oxidoreductase (WWOX) gene is located at FRA16D, a common fragile site involved in human cancer. Targeted deletion of Wwox in mice causes increased spontaneous tumor incidence, confirming that WWOX is a bona fide tumor suppressor gene. We show that stable transfection of WWOX into human PEO1 ovarian cancer cells, containing homozygous WWOX deletion, abolishes in vivo tumorigenicity, but this does not correlate with alteration of in vitro growth. Rather, WWOX restoration in PEO1, or WWOX overexpression in SKOV3 ovarian cancer cells, results in reduced attachment and migration on fibronectin, an extracellular matrix component linked to peritoneal metastasis. Conversely, siRNA-mediated knockdown of endogenous WWOX in A2780 ovarian cancer cells increases adhesion to fibronectin. In addition, whereas there is no WWOX-dependent difference in cell death in adherent cells, WWOXtransfected cells in suspension culture display a proapoptotic phenotype. We further show that WWOX expression reduces membranous integrin A3 protein but not integrin A3 mRNA levels, and that adhesion of PEO1 cells to fibronectin is predominantly mediated through integrin A3. We therefore propose that WWOX acts as an ovarian tumor suppressor by modulating the interaction between tumor cells and the extracellular matrix and by inducing apoptosis in detached cells. Consistent with this, the suppression of PEO1 tumorigenicity by WWOX can be partially overcome by implanting these tumor cells in Matrigel. These data suggest a possible role for the loss of WWOX in the peritoneal dissemination of human ovarian cancer cells. [Cancer Res 2009;69(11):4835–42]
Migration as opportunity? A case study of Polish women : Migrants in the UK and returnees in Poland

Migration from the new European Union (EU) Member States to the United Kingdom (UK) has been identified as one of the most significant social phenomena of recent times and has been studied extensively, particularly since 2004. Although gendered studies of migration are now gaining recognition, there is limited literature in relation to Polish women. There is now much evidence to support the view that migrant women constitute a large proportion of international migrants; within the European context, migrant women already outnumber their male counterparts. Drawing on a review of secondary literature and preliminary findings from new qualitative research undertaken in Poland and the UK, this paper explores how Polish migrant women negotiate their lives in regard to work and welfare responsibilities when exercising their rights as EU citizens. It is argued that migrant women should be seen as active decision makers and that migration may be considered as an opportunity to bring about change in relation to gender roles. It is concluded that migration presents an opportunity to re evaluate gender norms.
Staphylococcus aureus Biofilms and their Impact on the Medical Field

Despite the discovery of antibiotics, the battle against bacteria is so far in their favor, spe - cifically because bugs are able to develop a superstructure named biofilm, to resist and to survive in the environment. Nosocomial infections, a major health problem, are due at 80% to biofilm‐associated infection, and Staphylococcus aureus is the leading bacteria species in this domain. Moreover, the antimicrobial resistance of this bacterial commu - nity is accentuated when it is formed by superbugs such as methicillin‐resistant S. aureus (MRSA). In this chapter, the mechanism and the physiology of S. aureus biofilm as well as their consequences in the clinical domains are described. To complete the vision on S. aureus biofilms, some “anti‐biofilm” strategies will be highlighted.
How nascent community enterprises build legitimacy in internal and external environments

ABSTRACT How nascent community enterprises build legitimacy in internal and external environments. Regional Studies. Community enterprises have become a widely used mechanism in addressing problems associated with socio-economic decline in rural areas. Using a legitimacy perspective, this paper explores how emerging community enterprises access resources needed to start and sustain their operations. Studying two music festivals that aim to improve the identity and economy of rural communities, three legitimation strategies emerge: conformance to the internal (rural community) environment; conformance to the external (cultural festival) environment; and changing the internal (rural community) environment. The legitimation process requires different legitimacy-building strategies within different environments, and community enterprises can benefit from differences in legitimacy judgements.
Relating independent components to free-vibration modal responses

In recent literature, attempts have been made to apply Independent Component Analysis (ICA) techniques to the modal identification problem. Paramount to this task is establishing a relationship between the source components realized using the suggested ICA technique and modal responses. In this paper, the relationship between independent components and free-vibration modal responses is discussed. Theoretical arguments are presented for responses of undamped systems and arguments are extended to damped responses.
Anu Eskelinen PLANT COMMUNITY DYNAMICS IN TUNDRA : PROPAGULE AVAILABILITY , BIOTIC AND ENVIRONMENTAL CONTROL

Plant community composition and diversity are determined by the balance between rates of immigration and extinction. Processes of immigration to a local community, i.e. propagule availability and dispersal of propagules between and within habitats, set the upper limit for the pool of species potentially capable of coexisting in a community, while local biotic interactions, i.e., competition, facilitation, herbivory and interactions with below-ground ecosystem components, and environmental factors control colonisation and establishment, and determine the persistence and dynamics of already existing species. In this thesis, I studied (1) the interactions between propagule availability, biotic and environmental constraints on colonisation, and (2) the interdependence between biotic and environmental factors regulating community processes in already established resident vegetation. First, I found that both propagule availability and competition with adult plants limited the rates of colonisation and total community diversity in a relatively low-productive tundra ecosystem. Long-term exclusion of mammalian herbivores and alleviation of nutrient limitation by fertilization increased the intensity of competition with established vegetation, and diminished immigration rates. In addition, I also found that community openness to colonization depended on the initial community properties, i.e., the functional composition and the traits of dominant plants in resident vegetation, which mediate the effects of nutrient addition and biomass removal on immigration rates. Second, adult plants in the resident vegetation experienced an increased extent of neighbourhood competition and herbivory in nutrient enriched conditions and in naturally more fertile habitats. However, the effects were also species-specific. On a community level, release from heavy grazing favoured lichens over graminoids and increased species richness. Furthermore, I also showed that plant community composition was strongly linked with soil organic matter quality and microbial community composition, and that these vegetation-soilmicrobe interactions varied along a gradient of soil pH. Overall, my results emphasise that propagule availability, biotic and environmental control over community processes are strongly interconnected in tundra ecosystems. Especially, my findings highlight the role of plant competition and herbivory and their dependence on soil nutrient availability in governing colonisation and resident community dynamics. My results also indicate that plant functional composition and traits of dominant plants are of great importance in channelling community responses to external alterations and dictating plant-soil interactions.
Housing Default: Theory Works and So Does Policy

Using a national loan level data set we examine loan default as explained by local demographic characteristics and state level legislation that regulates foreclosure procedures and predatory lending through a hierarchical linear model. We observe significant variation in the default rate across states, with lower default levels in states with higher temporal and financial costs to lenders when controlling for loan and location conditions. The results are notable given that many of the observed loans were sold to investors in national and international markets. State level legislative influences provide a foundation for discussion of national level policy that further regulates predatory lending and financial institution foreclosure activities.
A learning pathway for whole numbers that informs mathematics teaching in the early years

This paper reports on the development of a Learning Pathway for Number (LPN) with the aim of facilitating the teaching and learning of whole number in the early primary grades (Grades R – 4) within the South African educational context. The development of the LPN was based on the Dutch Learning/Teaching Trajectory for Whole Number (Van den Heuvel-Panhuizen, 2001). This paper describes a case study that presents the development of the LPN with three teacher groups (teachers from a school improvement project, teachers from high-performing schools and pre-service student teachers). The LPN is a conceptual framework based on five learning/teaching principles, namely the context, level, activity, interaction and the guidance principles. The benefit of this pedagogic tool adapted and refined for the South African context is that it provides a longitudinal view, highlighting milestones in the learning of number with the aim of deepening learners’ conceptual understanding of number over time. This case study reveals the importance of a devise that enables teachers to reflect on their mathematics content and pedagogy and bridges the theory-practice divide. It also highlights the critical issue of language and the use of appropriate terminology and activities in the classroom.
Induction of DNA damages upon Marek ’ s disease virus infection : implication in viral 1 replication and pathogenesis 2 3 Running title : DNA damage upon MDV infection

188 words / Importance: 134 words / Text: 5751 words 20 JVI Accepted Manuscript Posted Online 4 October 2017 J. Virol. doi:10.1128/JVI.01658-17 Copyright © 2017 American Society for Microbiology. All Rights Reserved. on M arch 1, 2020 by gest http/jvi.asm . rg/ D ow nladed fom
A Study and Survey on Sentiment Analysis

: In essence, Sentiment Analysis (SA) is detection and determination of the response of the targeted consumers to a certain brand or product or maybe even a situation. But there are much more potential in SA and emerging research in this area has attracted and involved many brilliant academic minds till date. Human mind is biased with preferences and judgements. So, automated machine to identify and clarify opinions presented in electronic unstructured text has come into picture and became the main focus of present research. There are also some challenges present in this field, such as, accuracy. Further ongoing researches are focusing on solving these problems and creating more efficient tool for SA.This paper tried to cover the study and research on SA that has been done so far. It also talks about the challenges and future aspects of SA.
Affects the Fatty Acid Composition of Arabidopsis thaliana seeds by Acetylating FATTY ACID DESATURASE 3 ( FAD 3 )

This article has been accepted for publication and undergone full peer review but has not been through the copyediting, typesetting, pagination and proofreading process, which may lead to differences between this version and the Version of Record. Please cite this article as doi: 10.1111/tpj.13300 This article is protected by copyright. All rights reserved. Received Date : 30-Jan-2016 Revised Date : 02-Aug-2016 Accepted Date : 05-Aug-2016 Article type : Original Article
A NON MODEL-BASED DAMAGE DETECTION TECHNIQUE USING DYNAMICALLY MEASURED FLEXIBILITY MATRIX

Abstract– Although a numerous methods exist for detecting damage in a structure using measured modal parameters, many of them require a correlated finite element model, or at least, modal data of the structure for the intact state as the baseline. For beam-like structures, curvature techniques, e.g., mode shape curvature and flexibility curvature have been applied to localize damage. An approximate flexibility matrix can be derived using a small number of vibration modes whose columns are referred to as flexibility shapes. In this paper, a damage localization method based on changes in flexibility shapes as well as its curvature is developed. Differential Quadrature Method (DQM) has been implemented to obtain the curvatures of flexibility shapes. It was shown that the method works well using the damaged model alone. To reduce the potential error due to differentiation of experimental data, a moving curve fit method has been implemented on flexibility shapes. The capability of the proposed method is demonstrated through numerical and experimental case studies.