Miracle-dz/UniFAR-FTUs huggingface dataset:
1024-Channel 3 D Ultrasound Digital Beamformer in a Single 5 W FPGA

3D ultrasound, an emerging medical imaging technique that is presently only used in hospitals, has the potential to enable breakthrough telemedicine applications, provided that its cost and power dissipation can be minimized. In this paper, we present an FPGA architecture suitable for a portable medical 3D ultrasound device. We show an optimized design for the digital part of the imager, including the delay calculation block, which is its most critical part. Our computationally efficient approach requires a single FPGA for 3D imaging, which is unprecedented. The design is scalable; a configuration supporting a 32×32channel probe, which enables high-quality imaging, consumes only about 5W.
EXPERIENTIAL TOURISM DEVELOPMENT ON LANNA LOCAL PLANT-BASED GASTRONOMY

The rise in plant-based gastronomy has boosted demand for plant-based food tours around the world. This study aims to identify the elements that contribute to the local plant-based gastronomy tourism experience, develop a resource utilization model, and create guidelines for the development of experiential tourism. A mixed-method design is employed. The research sites included three ecological areas in Chiang Mai province, namely highland, upland, and lowland. Data were collected via a questionnaire and a focus group of 30 key stakeholders, which was comprised of 10 groups (Thai and foreign tourists with a special interest in the topic, chefs, travel agents, tour guides, target communities, tourism organizations, tourism academia, media, and local government organizations). The results revealed that the key elements contributing to the plant-based gastronomy tourism experience pertain to 21 local plants (among 190 plants found). The resource utilization model was developed in three stages: pre, during, and post-travel experiences. The experiential tourism development guidelines identify the groups of young chefs, and health conscious people, as the major target tourists. Good conservation of local plants and effective communication using social media are also crucial to development.
The centrality of groups and classes

This paper extends the standard network centrality measures of degree, closeness and betweenness to apply to groups and classes as well as individuals. The group centrality measures will enable researchers to answer such questions as ‘how central is the engineering department in the informal influence network of this company? ’ or ‘among middle managers in a given organization, which are more central, the men or the women? ’ With these measures we can also solve the inverse problem: given the network of ties among organization members, how can we form a team that is maximally central? The measures are illustrated using two classic network data sets. We also formalize a measure of group centrality efficiency, which indicates the extent to which a group's centrality is principally due to a small subset of its members.
EVALUATION OF ANTI-INFLAMMATORY POTENTIAL OF SOME NEW FERULLIC ACID DERIVATIVES

The anti-inflammatory potential of new thiazolidin-4-one derivatives of ferulic acid was evaluated using in vitro assays based on bovine serum albumin denaturation and human red blood cell membrane stabilization. The most intense anti-denaturation effect was showed by compounds 1e (R = 2-NO2), 1f (R = 2-OH) and 1d (R = 4-NO2) for which the anti-denaturation activity was more intense than ferulic acid and comparable with diclofenac. Considering the ability of the tested compounds to protect the erythrocytes membrane it was observed that at 500 μg/mL, all compounds showed a protection comparable or higher than diclofenac and ferulic acid. The results support the favourable influence of the thiazolidine-4-one moiety on the anti-inflammatory effect of the ferulic acid derivatives.
Block‐like plate movements in eastern Anatolia observed by InSAR

The question whether continental plates deform internally or move as rigid blocks has been debated for several decades. To further address this question, we use large‐scale interferometric synthetic aperture radar (InSAR) data sets to study how eastern Anatolia and its surrounding plates deform. We find that most of the deformation is focused at the North and East Anatolian faults and little intraplate deformation takes place. Anatolia is therefore moving, at least its eastern part, as a uniform block. We estimate the slip velocity and locking depth of the North Anatolian fault at this location to be 20 mm/yr and ~14 km, respectively. High deformation gradient found near the East Anatolian fault, on the other hand, suggests that little stress is accumulating along the eastern sections of that fault.
Failure investigation and asset management of combined measuring instrument transformers

Réseau de Transport d'Électricité Abstract Asset management of instrument transformers (ITs) has gained momentum in recent years due to their large population in the network and the potential adverse impacts of their increasing number of failures. This study investigates the failure cause of a family of combined measuring ITs via temperature profile simulations and consideration of moisture migration behaviour in an oil‐impregnated paper insulation system. The temperature difference experienced by an IT, particularly throughout summer, together with a relative saturation hysteresis phenomenon could have caused a lower dielectric strength that led to failures. The study also offers insights into factors influencing the probability of failures through analysis on the lifetime data from both graphical survival function plots and statistical Cox model. In‐service age, operating voltage level and environment appear to have an influence on failure rate.
Word Embedding Aware Convolutional Networks for Sentiment Analysis

Convolutional neural networks (CNNs) have become extremely popular models for text classification. Traditional architectures perform convolutions on dense vector representations of the input text, also known as word embeddings. While researchers have explored various architectures to advance the state-of-the-art, the importance of the initial word embedding layer has not been considered as closely. This paper seeks to bridge this gap by empirically analyzing how using different word embeddings impact performance.1
Establishing Components of Programmes to Reduce Restrictive Practices in Adult Mental Health Inpatient Services: A Behaviour Change Technique Analysis

Background: Incidents that threaten service user and staff safety occur frequently in adult mental health inpatient settings, often resulting in restrictive practices such as restraint and seclusion. These carry significant risks, including physical and psychological harms to service users and staff, as well as costs to the NHS. Numerous complex interventions have been developed which aim to reduce the use of restrictive practices. Aims: The aims were to identify, standardise and report the effectiveness of components of interventions that seek to reduce restrictive practices in adult mental health inpatient settings, using the Behaviour Change Technique taxonomy. Methods: A systematic mapping review of literature identified in health and social care research databases and unpublished sources (including social media) was undertaken. Records were quality appraised using the MMAT. Records of interventions to reduce any form of restrictive practice used with adults in mental health services were included. The resulting dataset for extraction was guided by WIDER, Cochrane and theory coding guidelines. The BCT taxonomy was systematically applied to each identified intervention.Results: The final dataset comprised 175 records reporting 150 interventions, 109 of which had been formally evaluated. The most common intervention targets were seclusion and/or restraint reduction. The most common evaluation approach was a non-randomised design. There were only six randomised controlled trials. The number of BCTs identified per intervention ranged from 1-33 (mean:8). The most common strategy was staff training. BCTs from 14 of a possible 16 clusters were detected. Over two thirds of the BCTs mapped onto four of the 14 clusters: ‘Goals and planning’; ‘Antecedents’; ‘Shaping knowledge’; ‘Feedback and monitoring’. Those BCTs which were found in all the interventions were similar to those found in those interventions which demonstrated statistically significant effects. Conclusions: Studies of interventions to reduce restrictive practices appear to be diverse quality. Interventions tended to contain multiple components delivered in multiple ways. Further research could enhance the evidence base prior to future commissioning decisions. Separate testing of individual procedures, for example, audit and feedback, could ascertain the more effective intervention components and improve understanding of content and delivery. Registration: The study is registered as PROSPERO 2018 CRD42018086985 Available from: http://www.crd. york.ac. uk/PROSPERO/display_record. php? ID=CRD42018086985
Burnout: Moving beyond the status quo.

Burnout has been defined as a job-induced syndrome combining emotional exhaustion, depersonalization/cynicism, and a sense of reduced personal accomplishment. In this article, we expand on past analyses of burnout by reviewing key, yet overlooked, problems affecting the construct. We concomitantly examine the implications of these problems for the overall validity of burnout research. Our work shows that burnout research is undermined by 4 main problems. First, what constitutes a case of burnout is unclear. Second, the basic conceptualization and operationalization of burnout are ill aligned. Third, burnout is unlikely to be the specifically job-induced syndrome it has been posited to be. Fourth, the discriminant validity of the burnout construct is unsatisfactory. These fundamental problems, disregarded for decades, render burnout research inconclusive. This state of affairs (a) bears on researchers’ and practitioners’ ability to monitor and protect workers’ health and (b) prevents public health policymakers from producing authoritative recommendations. The burnout construct thus appears to not well serve the goal of promoting occupational health. The depression construct may offer occupational health specialists a way out of the “burnout impasse. ” Depression is diagnosable. Like burnout, depression can be studied dimensionally (i.e., as a process) and examined from both an individual and a social standpoint. Methods for investigating the etiological link between depressive symptoms and disorders and job stress are available.
Modeling of Information Sharing on the Business Social Media

Social media, which support communication on the Internet, continue to spread rapidly. SNSs and micro-blogs are typical services. This research proposes methods for efficient information sharing through social media, especially intra-firm systems for information sharing of research or expertise. In this research, a simple model of social media is provided, whose users share information by directly referring to other users. The authors focused on a particular intra-firm social media and analyzed the usage of its communities. By applying a clustering method, they are classified into six groups and analyzed their characteristics and occupation rate. Finally, the authors proposed a method that supports information sharing and evaluated it by agent-based simulation using our proposed model. The authors clarified that not only encouraging users to post articles but also giving them an opportunity to refer to the existing community' s history is effective for information sharing.
Submillimeter and Far-Infrared Polarimetric Observations of Magnetic Fields in Star-Forming Regions

Observations of star-forming regions by the current and upcoming generation of submillimeter polarimeters will shed new light on the evolution of magnetic fields over the cloud-to-core size scales involved in the early stages of the star formation process. Recent wide-area and high-sensitivity polarization observations have drawn attention to the challenges of modeling magnetic field structure of star forming regions, due to variations in dust polarization properties in the interstellar medium. However, these observations also for the first time provide sufficient information to begin to break the degeneracy between polarization efficiency variations and depolarization due to magnetic field sub-beam structure, and thus to accurately infer magnetic field properties in the star-forming interstellar medium. In this article we discuss submillimeter and far-infrared polarization observations of star-forming regions made with single-dish instruments. We summarize past, present and forthcoming single-dish instrumentation, and discuss techniques which have been developed or proposed to interpret polarization observations, both in order to infer the morphology and strength of the magnetic field, and in order to determine the environments in which dust polarization observations reliably trace the magnetic field. We review recent polarimetric observations of molecular clouds, filaments, and starless and protostellar cores, and discuss how the application of the full range of modern analysis techniques to recent observations will advance our understanding of the role played by the magnetic field in the early stages of star formation.
Silicon Alleviates Iron Deficiency in Barley by Enhancing Expression of Strategy II Genes and Metal Redistribution

The beneficial effects of silicon (Si) have been shown on plants using reduction-based strategy for iron (Fe) acquisition. Here we investigated the influence of Si on Fe deficiency stress alleviation in barley (Hordeum vulgare), a crop plant which uses the chelation-based strategy for Fe acquisition. Analyses of chlorophyll content, ROS accumulation, antioxidative status, concentrations of Fe and other micronutrients, along with the expression of Strategy II genes were studied in response to Si supply. Si successfully ameliorated Fe deficiency in barley, diminishing chlorophyll and biomass loss, and improving the activity of antioxidative enzymes, resulting in lowered reactive oxidative species accumulation in the youngest leaves. Alleviation of Fe deficiency stress correlated well with the Si-induced increase of Fe content in the youngest leaves, while it was decreased in root. Moreover, Si nutrition lowered accumulation of other micronutrients in the youngest leaves of Fe deprived plants, by retaining them in the root. On the transcriptional level, Si led to an expedient increase in the expression of genes involved in Strategy II Fe acquisition in roots at the early stage of Fe deficiency stress, while decreasing their expression in a prolonged stress response. Expression of Strategy II genes was remarkably upregulated in the leaves of Si supplied plants. This study broadens the perspective of mechanisms of Si action, providing evidence for ameliorative effects of Si on Strategy II plants, including its influence on accumulation and distribution of microelements, as well as on the expression of the Strategy II genes.
The Macaque Cerebellar Flocculus Outputs a Forward Model of Eye Movement

The central nervous system (CNS) achieves fine motor control by generating predictions of the consequences of the motor command, often called forward models of the movement. These predictions are used centrally to detect not-self generated sensations, to modify ongoing movements, and to induce motor learning. However, finding a neuronal correlate of forward models has proven difficult. In the oculomotor system, we can identify neuronal correlates of forward models vs. neuronal correlates of motor commands by examining neuronal responses during smooth pursuit at eccentric eye positions. During pursuit, torsional eye movement information is not present in the motor command, but it is generated by the mechanic of the orbit. Importantly, the directionality and approximate magnitude of torsional eye movement follow the half angle rule. We use this rule to investigate the role of the cerebellar flocculus complex (FL, flocculus and ventral paraflocculus) in the generation of forward models of the eye. We found that mossy fibers (input elements to the FL) did not change their response to pursuit with eccentricity. Thus, they do not carry torsional eye movement information. However, vertical Purkinje cells (PCs; output elements of the FL) showed a preference for counter-clockwise (CCW) eye velocity [corresponding to extorsion (outward rotation) of the ipsilateral eye]. We hypothesize that FL computes an estimate of torsional eye movement since torsion is present in PCs but not in mossy fibers. Overall, our results add to those of other laboratories in supporting the existence in the CNS of a predictive signal constructed from motor command information.
Anterior to Midposterior Corpus Callosum Subregions Are Volumetrically Reduced in Male Alcoholics but Only the Anterior Segment Is Associated to Alcohol Use

Alcohol consumption seems to affect corpus callosum morphometry irrespectively of an alcohol use disorder (AUD) diagnosis. The present study examined the relationship between corpus callosum (CC) subregion volumes and alcohol use patterns in AUD and non-AUD subjects. Twenty-two male AUD patients and 23 healthy matched non-AUD subjects were recruited from March 2016 to July 2017. Volumetric data were acquired through Magnetic Resonance and analyzed by the FreeSurfer software. AUD subjects were in abstinence for 45.1 days ± 36.8 (SD), consumed higher amounts of alcohol and presented higher AUDIT scores than controls (p < 0.0001). A multivariate analysis corrected by age and tobacco use indicated that AUD patients presented smaller CC volumes compared to non-AUD subjects (p < 0.01), except for the posterior subregion. A multiple regression analysis corrected by age and tobacco use including CC volumes from all subjects and the amount of daily alcohol ingestion as variables indicated that anterior CC volume was negatively (p < 0.001) associated to alcohol consumption. This study demonstrated that CC subregions were smaller in AUD subjects, as expected, and that the volume of the anterior segment was inversely associated to increasing daily amounts of alcohol, indicating greater frontal region vulnerability to harmful alcohol effects.
Phytohormone and Chromatin Crosstalk: The Missing Link For Developmental Plasticity?

1 LBLGC, INRA, Université d’Orléans, EA1207 USC 1328, Orléans, France, 2 BIOSS Centre for Biological Signaling Studies, Institute for Biology III, University of Freiburg, Freiburg, Germany, 3 ESE, Ecology and Ecosystem Health, Agrocampus Ouest, INRA, Rennes, France, Department of Botany, Charles University, Prague, Czechia, Centre Algatech, Institute of Microbiology of the Czech Academy of Sciences, Trebon, Czechia, 6 Faculty of Science, University of South Bohemia in Ceske Budejovice, Ceske Budejovice, Czechia
Genome-Wide Identification and Characterization of Salvia miltiorrhiza Laccases Reveal Potential Targets for Salvianolic Acid B Biosynthesis

Laccases are widely distributed in plant kingdom catalyzing the polymerization of lignin monolignols. Rosmarinic acid (RA) has a lignin monolignol-like structure and is converted into salvianolic acid B (SAB), which is a representatively effective hydrophilic compound of a well-known medicinal plant Salvia miltiorrhiza and also the final compound of phenolic acids metabolism pathway in the plant. But the roles of laccases in the biosynthesis of SAB are poorly understood. This work systematically characterizes S. miltiorrhiza laccase (SmLAC) gene family and identifies the SAB-specific candidates. Totally, 29 laccase candidates (SmLAC1-SmLAC29) are found to contain three signature Cu-oxidase domains. They present relatively low sequence identity and diverse intron–exon patterns. The phylogenetic clustering of laccases from S. miltiorrhiza and other ten plants indicates that the 29 SmLACs can be divided into seven groups, revealing potential distinct functions. Existence of diverse cis regulatory elements in the SmLACs promoters suggests putative interactions with transcription factors. Seven SmLACs are found to be potential targets of miR397. Putative glycosylation sites and phosphorylation sites are identified in SmLAC amino acid sequences. Moreover, the expression profile of SmLACs in different organs and tissues deciphers that 5 SmLACs (SmLAC7/8/20/27/28) are expressed preferentially in roots, adding the evidence that they may be involved in the phenylpropanoid metabolic pathway. Besides, silencing of SmLAC7, SmLAC20 and SmLAC28, and overexpression of SmLAC7 and SmLAC20 in the hairy roots of S. miltiorrhiza result in diversification of SAB, signifying that SmLAC7 and SmLAC20 take roles in SAB biosynthesis. The results of this study lay a foundation for further elucidation of laccase functions in S. miltiorrhiza, and add to the knowledge for SAB biosynthesis in S. miltiorrhiza.
The Focal Play Therapy: A Clinical Approach to Promote Child Health and Family Well-being

Eating and evacuation disorders can cause serious health problems for children. Early recognition and early treatment require a multifactor intervention based on a collaborative relationship between pediatricians, psychotherapists and other health professionals. In this context the Focal Play Therapy (FPT) with children and parents is a psychodynamic model of intervention that improves parental ability to cope with child's difficulties. Parental engagement in child interventions allows to understand child's symptoms within family dynamics and to build an alliance with parents that represents a crucial variable of an effective psychological support for children and families. In the present study data were collected from 17 parental couples and their preschool children at two time points (1st and 6th FPT sessions) marking the first phase of this intervention. This phase was aimed to the assessment of child's symptoms within family relationships and to the promotion of the alliance with parents. Families were in treatment at the Psychological Consultation Center for Children and Parents located at the Department of Psychology of the University of Bologna (Italy). This Center provides health assessment and intervention services to children and their families. We investigated the alliance from both parents and therapist points of view along with other parental and child outcome variables implied in clinical works with children and families. Alliance scores were obtained through the Working Alliance Inventory and the System for Observing Family Therapy Alliances, two measures used in individual and family settings, respectively. Parenting stress and parent-child interactions were investigated using the Parenting Stress Index and the Emotional Availability Scales. Furthermore, paired t-tests were run to detect changes on parental and child variables. Findings advise that special attention should be paid to the building of an early alliance with parents. In this regard the FPT is specifically designed to promote the parent-therapist alliance in the context of child health and family well-being.