Miracle-dz/UniFAR-FTUs huggingface dataset:
Genetic study of congenital limb anomalies among Egyptian children

Objective: This study has been conducted to reveal genetically-determined factors that underlie the development of congenital limb anomalies among a sample of Egyptian infants and children. These data might prove useful in taking preventive measures and/or providing proper counseling to concerned families. Subjects and Methods: The study comprised studying 140 (One hundred and forty) Egyptian children with congenital limb anomalies. They consisted of (98) males and (42) females ranging in age from 10 days to 18 years. All cases were selected from among patients attending the outpatient medical genetics clinic, faculty of medicine, Ain-Shams university, Cairo-Egypt. Enrolled cases were subjected to a list of investigations including complete history with pedigree construction, anthropometric measurements and full clinical examination. In addition, specific radio-imaging studies and laboratory investigations were done for cases necessitating further diagnostic workup. Results: The results of the study revealed that isolated limb anomalies were found in (55) patients representing (39.3%) of cases. The remaining eighty five (85) patients constituting (60.7%) of enrolled cases comprised two groups: those with limb defects as part of a well defined genetic syndrome (Syndromic limb defects) (76 patients - 54.3%) and those with limb defects as part of a chromosomal aberration syndrome (9 patients - 6.4%). Genealogical data of the study revealed that parental consanguinity is found in (47.3%) of cases with isolated limb defects, in (72.3%) of cases with syndromic limb defects and in (44.4%) of cases with limb defects due to chromosomal abnormalities. Valid history of prenatal drug intake by the mother was found in (43.6%) of cases with isolated limb defects, in (25%) of syndromic limb defects and in none of the cases with chromosomal abnormalities. Conclusions: Detailed analysis of data of the study drew useful recommendations regarding many aspects like the possibility of prenatal diagnosis of most cases as well as the availability of many curative and/or palliative intervention measures for early detected and managed cases. Of prime importance, however, is the urgent need of alerting gynecologists and obstetricians taking care of pregnant women to the important role played by iatrogenic prescription of drugs during pregnancy in causation of many types of congenital limb anomalies. Cessation of this non-based evidence medical attitude is necessary and can result in a significant reduction in drug-induced congenital limb anomalies among newborns. Key Words: Limb anomalies, Egyptian children, consanguinity, chromosomal abnormalities.
Employing Handwriting without Tears® to Teach a 4-Year-Old Preschool Student to Write His Name with the Appropriate Size, Shape, and Form Combined with an Imitate/Trace/Copy/Memory Procedure.

The main purpose of this study was to evaluate the effectiveness of the prewriting and handwriting curriculum ® Handwriting Without Tears (HWT) in a preschool setting with a single student who has developmental delays and a suspected Autism Spectrum Disorder (ASD) diagnosis. Data were collected during the regular preschool day. The behavior measured was the student's ability to independently and accurately write his name given by the visual prompt “Name: ______” and verbal instructional cue “write your name”. A modified imitate, trace, copy, and memory ® procedure was used with the student with the instructional support and curriculum from the Handwriting Without Tears Get Set for School (Olsen, 2003) curriculum. In addition to this curriculum, first author created materials were also used. ® The overall outcomes indicated that the Handwriting Without Tears programs was successful in teaching that student who has severe developmental delays, tactile defensiveness, and sensory processing deficits to write his name.
Low-SAR Miniaturized Handset Antenna Using EBG

Advances in wireless communications have paved the way for wide usage of mobile phones in modern society, resulting in mounting concerns surrounding its harmful radiation. Energy absorption in human biological tissues can be characterized by spe- cific absorption rate (SAR). This value refers to the actual amount of electromagnetic energy absorbed in the biological tissues, thus a lower value of SAR indicates a lower radiation exposure risk to the human body. So, our challenge is to introduce mobile handset antennas with low SAR and operating at all mobile and wireless applications. In this chapter, novel configurations of single-element antenna are designed, simulated, fabricated, and measured. The antennas operate for most cellular applications: global system for mobile (GSM)-850/900, digital cellular system (DCS)-1800, personal commu nication service (PCS)-1900, universal mobile telecommunication system (UMTS)-2100, and long-term evolution (LTE) bands. The antennas also support wireless applications. The proposed antennas have a compact size and low SAR at all bands. Also, this chap - ter presents a comprehensive study on the performance of the antenna in the diﬀerent environments. Furthermore, the antenna performance is tested in the presence of head and hand in free space and in a car. The simulation and measurement results are in good agreement.
Hemolytic activity and production of germ tubes related to pathogenic potential of clinical isolates of Candida albicans

ABSTRACT We assessed the virulence factor profile and in vitro antifungal susceptibility of 27 hospital isolates of C. albicans; 19 of these were from infections (16 urinary and three blood), and the other eight were isolated from sites of colonization (two from hands of health professionals, and six from central venous catheters). The virulence factors assayed were germ tube formation and production of extracellular products (hemolysins, proteinases, and phospholipases). Susceptibility to fluconazole, itraconazole, voriconazole and amphotericin B was determined by E-test. Regarding the virulence factors, the infection isolates produced significantly more hemolysin and germ tubes than the colonization isolates (p 0.05). Amphotericin B showed the lowest minimum inhibitory concentrations for all the isolates. The highest resistance was observed for the azoles, especially in the clinical isolates. These results suggest that the capacity of C. albicans to produce hemolysins and germ tubes may be associated with its pathogenic potential. Colonization isolates may pose a high risk of nosocomial infection, especially when the yeasts show resistance to antifungals. Keywords : Nosocomial infection. Virulence. Candida albicans. Germ tube. Hemolysins. RESUMO Atividade hemolitica e producao de tubos germinativos relacionados ao potencial patogenico de isolados clinicos de Candida albicans O perfil de virulencia e o de susceptibilidade in vitro aos antifungicos de 27 amostras de C. albicans de origem hospitalar foi avaliado, sendo que 19 delas foram isoladas de infeccoes (16 urinarias e tres sanguineas) e as outras oito foram isoladas de colonizacao (duas de maos de profissionais da saude e seis de cateter venoso central). Os seguintes fatores de virulencia foram investigados: formacao de tubo germinativo e producao de compostos extracelulares (hemolisinas, proteinases e fosfolipases). Suscetibilidade ao fluconazol, itraconazol, voriconazol e anfotericina B foram determinadas por E-test. Em relacao aos fatores de virulencia, os isolados de infeccao produziram significativamente mais hemolisina e tubos germinativos do que os de colonizacao (p 0.05). Anfotericina B mostrou as menores concentracoes inibitorias minimas para todos os isolados. Maiores indices de resistencia foram observados aos azolicos, especialmente entre os isolados clinicos. Estes resultados sugerem que a capacidade de C. albicans produzir hemolisinas e tubos germinativos pode estar associada com seu potencial patogenico. Por outro lado, leveduras em colonizacao podem oferecer alto risco para infeccao hospitalar, especialmente quando tem perfil de resistencia aos antifungicos. Palavras-chave : Infeccao hospitalar. Virulencia. Candida albicans. Tubo germinativo. Hemolisinas.
A Distributed Cooperative Trust Based Intrusion Detection Framework for MANETs

Mobile Ad Hoc Network (MANET) is a collection of nodes, which form an infastructureless topology. There is no central access point or centralized management. For their nature, MANETs present a number of unique problems for Intrusion Detection Systems (IDS). This paper introduces an intrusion detection framework for MANETs, which is based on trust relationship. In our proposed framework, intrusion detection system relies on local and global determination of attacks within network and carried out in a distributed fashion with cooperation among nodes. Trust in this manner is an important issue. The nodes watch suspicious activities of neighboring nodes. An intrusion detection alert message is disseminated throughout the network to report the anomaly. Reputation of intrusion detection alert messages is used for trust assessment. The proposed framework aims to utilize a distributed and cooperative trust based intrusion detection system to cope with the disadvantages drawn from mobility of nodes and the probability of selfishness, which are unique to MANETs.
SEISMIC RESPONSE OF RC HIGH-RISE BUILDINGS IN JAPAN CONSIDERING INTERNAL VISCOUS DAMPING

Seismic response analyses as an RC high-rise design are in general performed against two different levels of earthquake intensities. Stiffness-proportional damping is chosen for its internal viscous damping. It is customary to use a certain value as a damping ratio in the first mode. On the other hand, recorded values of damping ratios for small earthquake intensity level tend to be smaller than the chosen value for the analysis design of high-rise structures. The variations of seismic response values are evaluated while those analyses are conducted for the various sizes of internal viscous damping. The analysis results show that maximum response values depend on the values of damping constant for the first mode and the differences of damping constant for higher modes. Furthermore, choosing instantaneous stiffness-proportional damping for analysis model, the fluctuating ratios of response values derived from using several cases of damping constant (h1) to those derived from using a damping constant of h1=3% are presented to evaluate the effect of internal viscous damping for earthquake-resistant design. The results show that the response values against large scale intensity motions for h1=2% (instantaneous stiffness-proportional model) are greater among base-shear coefficient, overturning moment, and whole displacement angle by 10% than those for h1=3%. The maximum response values for various values of internal viscous damping are studied for RC high-rise buildings in Japan. Consequently, the effects of internal viscous damping on maximum response values are thoroughly evaluated.
Prediction of Cancer Subtypes using Fuzzy Hypersphere Clustering Neural Network

Summary The classification of different tumor types is of great importance in cancer diagnosis and drug discovery. However, most previous cancer classification studies are clinical-based and have limited diagnostic ability. Cancer classification using gene expression data is known to contain the keys for addressing the fundamental problems relating to cancer diagnosis and drug discovery. The recent advent of DNA microarray technique has made simultaneous monitoring of thousands of gene expressions possible. We propose a new method of classification system namely, the fuzzy hypersphere clustering neural network (FHCNN) which combines clustering and classification inorder to differentiate cancer tissues such as acute myeloid leukemia (AML) and acute lymphoblastic leukemia (ALL). Experimental results show that our FHCNN model using one outstanding gene, Zyxin achieves the best classification accuracy of 94.12% where as other state-of-art methods could reach the best accuracy of 91.18%. Moreover FHCNN is more stable, and contains less number of parameter adjustments compared to all the other classification methods.
A Study of Teachers Opinions and Experiences on the Use of Computers and Laptops in Classrooms in the United Arab Emirates

Significant investments have been made by educational institutions as well as parents and students purchasing computers and laptops on the pretence that this equipment is as much part of the teaching and learning environment as are pens, books and teachers. The issue as to the 'impact' of this new innovation upon educational practices has generated mixed findings. Teachers at all levels of the education sector are now using (and being expected to use) computers and laptops in their classrooms. In order to assess the affect of computers/laptops on the dynamics of the teaching and learning environment a questionnaire was circulated to teachers currently undertaking a Masters in Education degree programme in order to gather teachers opinions and experiences regarding the use of computers and laptops in their classrooms. The results reveal that teachers in the United Arab Emirates (UAE) in both the public and private sector, that had been educated in various parts of the world, were able to identify key issues pertaining to the advantages and disadvantages to the use of technology in their classrooms. Significant concerns regarding the lack of suitable training in how to deal with and manage the technology from a pedagogical perspective were raised as well as the issue of teaching strategies that would enable suitable technology based classroom management practices.
Impact of foliar fungi on dogroses

Roses are not only popular ornamentals, but some of the wild species also supply us with food, cosmetics and even medicine. Wild roses of the section Caninae, commonly known as dogroses, are often used for their fruits but may also harbour resistance genes that can be used for breeding healthier ornamentals. However, due to the special so-called Canina-meiosis, inheritance is mainly matroclinal with a comparatively small paternal contribution.Therefore, it is important to know how resistance genes are transmitted to the progeny. Different foliar fungi damage roses, most important are blackspot (Marssonina rosae) and powdery mildew (Sphaerotheca pannosa). Furthermore, rust (Phragmidium spec.) is known to infect roses, and a leafspot-disease called Sphaceloma rosarum has recently become more serious. Two fields with dogroses, one with plants obtained by open pollination in wild populations, and one with plants obtained from intra- and interspecific crosses, were evaluated for blackspot, powdery mildew, rust and leafspots in the autumn of 2005. The data was statistically analysed with Systat 5.2. Additionally, microscopic investigations were conducted to gather more knowledge about the appearance of the diseases on the dogrose species. Interestingly, no symptoms of powdery mildew were found in either field, although the fungus infected wild roses of a different section in a field closeby. The investigated dogrose plants had previously been damaged by powdery mildew, suggesting that the presently achieved tolerance is due to plant age or exterior influences. Surprisingly few symptoms of blackspot were found and they differed considerably from those found on ornamental cultivars, indicating a lower susceptibility. Most important in 2005 was rust, followed by leafspot symptoms. The latter were found to be caused not only by Sphaceloma rosarum, but also by Septoria rosae, a fungus never before noticed at Balsgard. The two leafspot diseases produce similar-looking spots that may vary somewhat depending on the host species, and can be properly discriminated only in a microscope. The rose species vary in their disease susceptibility but there was no evidence of really high levels of resistance. Amount of disease symptoms was mainly matroclinally inherited, but a contribution of the pollen parent was also found. Plants with Rosa rubiginosa as seed parent appear to be the most promising candidates for plant breeding since they performed best for rust and leafspots, and might even be resistant to Septoria-leafspot.
Ectoparasites help to maintain variation in cell-mediated immunity in the blue tit–hen flea system

Hypothesis: Host-parasite interactions have the potential to maintain genetic variation, especially in traits related to defence against parasites. Organism: Blue tit (Cyanistes caeruleus) nestlings. Methods: Rear nestlings in artificially created conditions of low and high abundance of ectoparasitic hen fleas (Ceratophyllus gallinae). Cross-foster siblings between these environments to estimate parasite-induced genotype-environment interactions. Measure components of phenotypic variance in morphology (tarsus length and body mass) and in immune defence (plasma immunoglobulins and cell-mediated immunocompetence). Results: Hen flea infestation lowered growth, cell-mediated immunocompetence, and haematocrit. Genotype-environment interactions were observed in cell-mediated immunocompetence, body mass, and haematocrit, with significant crossing reaction norms for cell-mediated immunocompetence and haematocrit. Immunoglobulin concentrations were unaffected by fleas. Thus, host-parasite interactions constrain the expression and evolvability of some traits, but also create genotype-environment interactions with the potential to maintain genetic variation in immune defence.
Denitrification in marine sediments: A model study

The rate and factors controlling denitrification in marine sediments have been investigated using a prognostic diagenetic model. The model is forced with observed carbon fluxes, bioturbation and sedimentation rates, and bottom water conditions. It can reproduce rates of aerobic mineralization, denitrification, and fluxes of oxygen, nitrate, and ammonium. The globally integrated rate of denitrification is estimated by this model to be about 230-285 Tg N yr(-1), with about 100 Tg N yr(-1) occurring in shelf sediments. This estimate is significantly higher than literature estimates (12-89 Tg N yr(- 1)), mainly because of a proposed upward revision of denitrification rates in slope and deep-sea sediments. Higher sedimentary denitrification estimates require a revision of the marine nitrogen budget and lowering of the oceanic residence time of nitrogen down to about 2 x 10(3) years and are consistent with reported low N/P remineralization ratios between 1000 and 3000 m. Rates of benthic denitrification are most sensitive to the flux of labile organic carbon arriving at the sediment-water interface and bottom water concentrations of nitrate and oxygen. Denitrification always increases when bottom water nitrate increases but may increase or decrease if oxygen in the bottom water increases. Nitrification is by far the most important source of nitrate for denitrification, except for organic-rich sediments underlying oxygen-poor and nitrate-rich water. [KEYWORDS: Organic-matter; biogeochemical cycles; early diagenesis; atmospheric co2; benthic fluxes; sea-floor; ocean; carbon;nitrogen; nutrient]
Supervisor Support, Co-Worker Support and Employee Retention: Developing and Testing of an Integrative Model

The scope of the current study is to investigate the impact of supervisor and coworker support on the employee retention with mediating role of employee creativity and psychological empowerment. The unit of analysis for the study is individuals employed in service sector organizations of Pakistan. Total response rate of the data collection is 63%. Sample size is 378 employees of service industries. Sampling technique is convenience based and data collection method is cross-sectional. The study has its originality as an integrative model formulated with the combination of these variables has not been tested earlier specifically in service industry of Pakistan. Results of the study indicate that the support extended by the supervisor has a significant and direct relationship with employee retention with effective mediating role of psychological empowerment whereas employee creativity was not found to have any significant relationship with either of the independent variables. The Sample size is considered as a limitation. However the study revealed that organizations should encourage supervisor support and ensure formulation and implementation of employee concerned policies and procedures which will resultantly assist in employee retention. The study has its practical significance for policy makers, managers, supervisors and employees at all levels.
Submersion time , depth , substrate type and sampling method as variation sources of marine periphyton

Periphyton is an additional food source in African and Asian brackish and freshwater fish ponds. The present study was a preliminary assessment of periphyton development on artificial substrates in temperate marine ponds. The effects of submersion time, substrate type, water depth, and total or partial sampling methods on the quantity and quality of periphyton collected, were evaluated. Four types of substrate (W: wooden poles, S: smooth fiber-glass strips, m: mosquito screen (1 mm-mesh) and M: garden netting (5 mm-mesh)) were deployed in a marine pond, and periphyton was collected 15 and 30 days later. The total amount of periphyton per substrate unit was collected as one sample or as 5 sub-samples. Results showed that (i) periphyton biomass in a marine pond increased between day 15 and day 30, (ii) more periphyton was collected on mosquito screen than on wooden poles, fiberglass strips and garden netting, (iii) periphyton biomass increased with submersion depth, (iv) sub-sampling leads to an underestimate compared to whole unit sampling, and (v) a correction of periphyton weight must be carried out considering the dissolved inorganic salts present in periphyton samples from marine and brackish ponds. Whole substrate unit sampling using a tube and stopper is recommended to avoid underestimation of periphyton development. Finally, the autotrophic fraction in the periphyton communities was very low compared to periphyton developed on biodegradable substrates in fertilized tropical ponds. Studies on fertilization and use of biodegraded substrates (i.e. long-time submerged wood) are recommended to further optimize periphyton development in temperate marine ponds.
Credit risk management in Islamic banking

Tokom viševekovne prakse konvencionalnog bankarstva, razvijene su brojne tehnike i instrumenti za ublažavanje kreditnog rizika i proces njihove evolucije, zbog stalnih promena u bankarskom poslovanju, i dalje traje. Islamske banke, pak, još uvek nisu uspele da razviju autentične, šerijatski prihvatljive tehnike za upravljanje kreditnim rizikom u obimu dovoljnom da zadovolji njihove potrebe. Stoga, one su često primorane da koriste konvencionalne tehnike, čija je dosledna primena u islamskom bankarstvu, usled šerijatske neusklađenosti pojedinih tehnika ili načina na koji se one u konvencionalnom bankarstvu implementiraju, dosta ograničena. U ovom radu, analiziraćemo konvencionalne tehnike upravljanja i ublažavanja kreditnog rizika i njihovu primenjivost u islamskom bankarstvu, praksu upravljanja kreditnim rizikom u islamskim bankama, ostvarene rezultate i faktore koji utiču na pojavu i intenzitet kreditnog rizika u islamskom bankarstvu.