Miracle-dz/UniFAR-FTUs huggingface dataset:
Numerical Investigations on Magnetohydrodynamic Pump Based Microchannel Cooling System for Heat Dissipating Element

Numerical investigations are performed on the magnetohydrodynamic (MHD) pump-based microchannel cooling system for heat dissipating element. In the present study, the MHD pump performance is evaluated considering normal current density, magnetic flux density, volumetric Lorentz force, shear stress and pump flow velocity by varying applied voltage and Hartmann number. It is found that for a low Hartmann number, the Lorentz force increases with an increase in applied voltage and Hartmann number. The velocity distribution along dimensionless width, the shear stress distribution along dimensionless width, the magnetic flux density along the dimensionless width and radial magnetic field distribution showed symmetrical behavior. The MHD pump-based microchannel cooling system performance is evaluated by considering the maximum temperature of the heat dissipating element, heat removal rate, efficiency, thermal field, flow field and Nusselt number. In addition, the influence of various nanofluids including Cu-water, TiO2-water and Al2O3-water nanofluids on heat transfer performance of MHD pump-based microchannel is evaluated. As the applied voltage increased from 0.05 V to 0.35 V at Hartmann number 1.41, the heat removal rate increased by 39.5%. The results reveal that for low Hartmann number, average Nusselt number is increasing function of applied voltage and Hartmann number. At the Hartmann number value of 3.74 and applied voltage value of 0.35 V, average Nusselt numbers were 12.3% and 15.1% higher for Cu-water nanofluid compared to TiO2-water and Al2O3-water nanofluids, respectively. The proposed magnetohydrodynamic microcooling system is effective without any moving part.
Range-wide connectivity of priority areas for Greater Sage-Grouse: Implications for long-term conservation from graph theory

ABSTRACT The delineation of priority areas in western North America for managing Greater Sage-Grouse (Centrocercus urophasianus) represents a broad-scale experiment in conservation biology. The strategy of limiting spatial disturbance and focusing conservation actions within delineated areas may benefit the greatest proportion of Greater Sage-Grouse. However, land use under normal restrictions outside priority areas potentially limits dispersal and gene flow, which can isolate priority areas and lead to spatially disjunct populations. We used graph theory, representing priority areas as spatially distributed nodes interconnected by movement corridors, to understand the capacity of priority areas to function as connected networks in the Bi-State, Central, and Washington regions of the Greater Sage-Grouse range. The Bi-State and Central networks were highly centralized; the dominant pathways and shortest linkages primarily connected a small number of large and centrally located priority areas. These priority areas are likely strongholds for Greater Sage-Grouse populations and might also function as refugia and sources. Priority areas in the Central network were more connected than those in the Bi-State and Washington networks. Almost 90% of the priority areas in the Central network had ≥2 pathways to other priority areas when movement through the landscape was set at an upper threshold (effective resistance, ER12). At a lower threshold (ER4), 83 of 123 priority areas in the Central network were clustered in 9 interconnected subgroups. The current conservation strategy has risks; 45 of 61 priority areas in the Bi-State network, 68 of 123 in the Central network, and all 4 priority areas in the Washington network had ≤1 connection to another priority area at the lower ER4 threshold. Priority areas with few linkages also averaged greater environmental resistance to movement along connecting pathways. Without maintaining corridors to larger priority areas or a clustered group, isolation of small priority areas could lead to regional loss of Greater Sage-Grouse.
Influence of salidroside on expression level of endothelin-1 and its receptors under hypoxic conditions in chicken embryonic pulmonary artery smooth muscle cells.

Received: Revised: Accepted: Published online: November 06, 2015 January 04, 2016 January 19, 2016 March 11, 2016 Salidroside (SDS), a traditional Chinese medicine, possesses many important functional activities such as anti-hypoxia, anti-fatigue, enhancing work performance, and is especially famous in the treatment of mountain mal-hypoxia in Tibet. Here we designed the study to evaluate the pharmacological effect of SDS on expression of ET-1 and its receptors in hypoxia-treated pulmonary artery smooth muscle cells (PASMCs). Chicken embryonic PASMCs incubated with or without SDS for 1h were then subjected to the hypoxic exposure for 24h. We evaluated the expression levels of ET-1 and its receptors mRNA in treated PASMCs. Compared with the hypoxia-treated group, the levels of ET-1 gene expression were notably decreased in both the moderate dose group (80μg/ml) and the high dose group (120μg/ml) (P<0.01, P<0.05) respectively, but no obvious decrease was found in the low dose group (40μg/ml). Meanwhile, pretreatment with SDS (40, 80, 120μg/ml) was found to be effective in reducing (P<0.01, P<0.01, P<0.05) the expression levels of ETA in avian PASMCs exposed to hypoxic conditions in vitro. Moreover, pretreatment with SDS markedly attenuated (P<0.01) ETB mRNA expression levels in the low-dose group (40μg/ml) and the moderate-dose group (80μg/ml), while in high dose group (120μg/ml), there was no obvious decrease. Collectively, our findings showed that SDS has a significant influence on the expression of ET-1 and its receptors in hypoxia-treated avian PASMCs. ©2016 PVJ. All rights reserved
Optimizing Cropping Systems of Cultivated Pastures in the Mountain–Basin Systems in Northwest China

Cultivated pastures are effective supporting systems of natural grassland preservation and sustainable agriculture in arid regions of northwest China. The adaptive combination of forage species enhances the yields and ecological functions of cultivated pastures. Legume–grass intercropping is a valuable sowing regime because of the niche differentiation and resource acquisition. Understanding the effects of species interactions in legume–grass intercropping systems can provide scientific and practical guidance on cultivated pasture management. In this study, we conducted a field experiment to determine the advantages and effects of alfalfa (Medicago sativa L.) annual grass intercropping on cultivated pastures. We analyzed the data on population traits, community characteristics and dry matter in the growing period to evaluate the effects of variety and sowing patterns with the following treatments: three alfalfa varieties (Algonquin, Leafy king, WL354HQ) sown in monocultures and mixed with oat (Avena sativa L.) or sudangrass (Sorghum sudanense (Piper) Stapf. ) with two seeding ratios. Our results suggest that in mixtures, the plant traits of alfalfa were determined by their own characters at the earlier stage but were affected more by companion grass at the later stage. The annual forage grass companion impaired the growth of alfalfa during the growth period. In mixtures, sudangrass displayed a stronger inhibiting effect on alfalfa than oat. Alfalfa–grass intercropping was proved to be a feasible cropping practice in terms of yield, production stability and weed control, due to their complementary use of resources in comparison with alfalfa monocropping. Alfalfa–annual grass intercropping is a beneficial alternative strategy to obtain effective cultivated pastures in arid regions.
Structure of waterbird assemblages in fragmented coastal wetlands of Northeastern Algeria

This study was carried out from 2007-2017 at the ecological complex of the Jijel wetlands in the north-east of Algeria. Censuses were conducted during the twelve months of each year to study variation in richness and abundance of waterbird populations for each season. We used distance sampling (point count and transect methods). A total of sixty species (eleven orders and sixteen families) were recorded. The Anatidae and Scolopacidae families were the most numerous with thirteen species. The common coot (Fulica atra), and the Mallard (Anas platyrhynchos) were the most abundant and frequent species each year. About 70 % of the species recorded occur as migrants, passing between the western Palearctic and their winter quarters in North Africa. Phenologically, we found 15 % were breeders, and from the point of view conservation status, 56 % were rare, 40 % were protected by Algerian regulations and 8 % were threatened species listed in the Red List of the International Union for Conservation of Nature (IUCN). Our results of ornithological monitoring in the wetlands in Algeria show that action is needed to address the consequences between birds, human activities, and climate change.
Plastron Pigmentation Variation in a Coastal Turtle Species of Conservation Concern (Malaclemys terrapin)

Abstract Malaclemys terrapin inhabits salt marshes of the coastal United States and has been historically divided into seven subspecies. Two of the described subspecies, M. t. pileata and M. t. littoralis, occur along the western and eastern coastlines of Louisiana, respectively. To better understand potential boundaries of these two subspecies, we documented pigmentation variation of the plastron along the coast of Louisiana where the subspecies supposedly intergrade. Photographs of the plastron were taken of captured individuals and we quantified pigment with a photoprocessing software (ImageJ). We found pigmentation differences between sexes, with females having lighter plastrons than males. The plastron pigmentation of females decreased with increasing plastron length, whereas that of males varied by site but not length. Plastron pigmentation did not correlate with longitude in either sex, indicating that there is no geographical cline in this trait. We suggest that large females might be released from the predation pressure of gape-limited predators, and therefore, can stop production of melanin as they grow. However, males and smaller females maintain cryptic, dark plastrons. Little is known about the mechanisms behind melanization in freshwater turtles, but understanding the patterns of pigmentation variation in M. terrapin might be important for taxonomists and conservation managers.
The Role Of FER Kinase In Human Melanoma Growth and Invasion

i Co-Authorship Statement. ii Acknowledgments. iii List of Tables . viii List of Figures . ix List of Appendices . xi List of Abbreviations . xii Chapter 1 . 1
Innate potential of random genetic oligomer pools for recombination

The spontaneous emergence of function from prebiotic pools of informational polymers is a central conjecture of current origin of life scenarios. However, the innate functional capacity of random genetic polymer pools is unknown. Here, we have examined the ab initio activity of random and semi-random eicosamer pools of RNA, DNA and the unnatural genetic polymers ANA (arabino-), HNA (hexitol-) and AtNA (altritol-nucleic acids) with respect to a simple functional test: the capacity for intermolecular ligation and recombination. While DNA, ANA and HNA pools proved inert, naïve RNA and AtNA pools displayed diverse modes of intermolecular recombination in eutectic ice phases. Recombination appears linked to the vicinal ring cis-diol shared by RNA and AtNA. Thus, the chemical configuration that renders both susceptible to hydrolysis also enables substantial spontaneous intrapool recombination in the absence of activation chemistry with a concomitant increase in the compositional and structural complexity of recombined pools.
Orchestrating internal and external resources to achieve agility and performance: the centrality of market orientation

PurposeThis study examines the collaborative impact of networking capability and balanced agile project management (APM) on firm performance through the mediating role of market orientation and business process agility of medium and large telecommunication technology providers in Indonesia.Design/methodology/approachResearch data were collected from the executive management of telecommunication technology providers in Indonesia via a questionnaire survey to obtain 150 valid questionnaires for analysis. This study analyzed the overall model fit and causal relationship using confirmatory factor analysis (CFA) and structural equation modeling (SEM). FindingsThe results indicate that market orientation fully mediates the link between networking capability-business process agility and balanced APM-business process agility. Furthermore, business process agility mediates the relationship between market orientation and firm performance.Research limitations/implicationsThis study is based on a cross-sectional nature and might fail to capture the dynamic of the studied variables over an extended period.Originality/valueThe study extends the knowledge that dynamic capabilities, represented by networking capability and balanced APM, must be framed by market orientation to create customer value and improve bargaining position. However, market orientation alone is not enough in a highly dynamic business environment. Organization also requires business process agility, responsiveness and adaptability to timely address customers' needs and requirements.
BAZ2A safeguards genome architecture of ground‐state pluripotent stem cells

Chromosomes have an intrinsic tendency to segregate into compartments, forming long‐distance contacts between loci of similar chromatin states. How genome compartmentalization is regulated remains elusive. Here, comparison of mouse ground‐state embryonic stem cells (ESCs) characterized by open and active chromatin, and advanced serum ESCs with a more closed and repressed genome, reveals distinct regulation of their genome organization due to differential dependency on BAZ2A/TIP5, a component of the chromatin remodeling complex NoRC. On ESC chromatin, BAZ2A interacts with SNF2H, DNA topoisomerase 2A (TOP2A) and cohesin. BAZ2A associates with chromatin sub‐domains within the active A compartment, which intersect through long‐range contacts. We found that ground‐state chromatin selectively requires BAZ2A to limit the invasion of active domains into repressive compartments. BAZ2A depletion increases chromatin accessibility at B compartments. Furthermore, BAZ2A regulates H3K27me3 genome occupancy in a TOP2A‐dependent manner. Finally, ground‐state ESCs require BAZ2A for growth, differentiation, and correct expression of developmental genes. Our results uncover the propensity of open chromatin domains to invade repressive domains, which is counteracted by chromatin remodeling to establish genome partitioning and preserve cell identity.
Encapsulation of shoot tips and nodal segments of Cleistanthus collinus for short term storage and germplasm exchange

The encapsulation of nodal segments and shoot tips from in vitro raised Cleistanthus collinus (Roxb.) Benth and Hook (Euphorbiaceae) was performed using alginate (Gelling matrix) and calcium chloride (Complexing agent) for short term storage and germplasm preservation. The shoot re-growth frequency of encapsulated nodal segments and shoot tips after storage at 4oC for different time periods (up to 8 weeks) were also assessed. Different combination and concentration of sodium alginate and calcium chloride was tested for the proper bead formation. The perfect synthetic seeds were obtained through a combination of 4% sodium alginate and 100 mM calcium chloride in half strength Murashige and Skoog medium with 3% sucrose. The maximum shoot re-growth response of encapsulated nodes (95%) and shoot tips (90%) were obtained in MS medium supplemented with 1.0 mg/l BAP after 6 weeks of culture. Encapsulated explants stored at 4oC also produce maximum shoot regrowth frequency of 5.3 shoots / bead for nodal segments and 3.3 shoots / bead for shoot tips in subsequent weeks of transfer. There was higher response in nodal segments compared to shoot tip explants. The re-grown shoots from the encapsulated explants rooted best on half strength MS medium with 0.5 mg/l IAA. The regenerated plants were successfully hardened and acclimatized.
Mediofrontal theta‐band oscillations reflect top‐down influence in the ventriloquist illusion

In the ventriloquist illusion, spatially disparate visual signals can influence the perceived location of simultaneous sounds. Previous studies have shown asymmetrical responses in auditory cortical regions following perceived peripheral sound shifts. Moreover, higher‐order cortical areas perform inferences on the sources of disparate audiovisual signals. Recent studies have also highlighted top‐down influence in the ventriloquist illusion and postulated a governing function of neural oscillations for crossmodal processing. In this EEG study, we analyzed source‐reconstructed neural oscillations to address the question of whether perceived sound shifts affect the laterality of auditory responses. Moreover, we investigated the modulation of neural oscillations related to the occurrence of the illusion more generally. With respect to the first question, we did not find evidence for significant changes in the laterality of auditory responses due to perceived sound shifts. However, we found a sustained reduction of mediofrontal theta‐band power starting prior to stimulus onset when participants perceived the illusion compared to when they did not perceive the illusion. We suggest that this effect reflects a state of diminished cognitive control, leading to reliance on more readily discriminable visual information and increased crossmodal influence. We conclude that mediofrontal theta‐band oscillations serve as a neural mechanism underlying top‐down modulation of crossmodal processing in the ventriloquist illusion.
FORMULA SAE REAR SUSPENSION DESIGN

The purpose of this report is to investigate the design development and evaluate the structural and functional performance of the proposed system for the 2019 competition. With the review of the literature surrounding rear suspension systems, FSAE standards, analysis techniques and important design parameters, the foundation for the proposed James Cook University (JCU) 2019 rear suspension system is established. This paper is highlighted the development and analysis path undertaken in the construction of rear suspension system befitting a Formula SAE vehicle. Formula SAE is an international student competition centered on the design, construction and racing of an internal combustion vehicle. All parts are designed via SolidWorks and FEA testing is incorporated using ANSYS to test out various loads under different scenarios in racing. Main components including beam axle, trailing arms, brackets, spring and damper are covered in this paper. The design is focused on providing a low cost and easy to manufacture design which operate for infinite life cycles.
Scaling single cell transcriptomics through split pool barcoding

Constructing an atlas of cell types in complex organisms will require a collective effort to characterize billions of individual cells. Single cell RNA sequencing (scRNA-seq) has emerged as the main tool for characterizing cellular diversity, but current methods use custom microfluidics or microwells to compartmentalize single cells, limiting scalability and widespread adoption. Here we present Split Pool Ligation-based Transcriptome sequencing (SPLiT-seq), a scRNA-seq method that labels the cellular origin of RNA through combinatorial indexing. SPLiT-seq is compatible with fixed cells, scales exponentially, uses only basic laboratory equipment, and costs one cent per cell. We used this approach to analyze 109,069 single cell transcriptomes from an entire postnatal day 5 mouse brain, providing the first global snapshot at this stage of development. We identified 13 main populations comprising different types of neurons, glia, immune cells, endothelia, as well as types in the blood-brain-barrier. Moreover, we resolve substructure within these clusters corresponding to cells at different stages of development. As sequencing capacity increases, SPLiT-seq will enable profiling of billions of cells in a single experiment.
FERMENTED AND NON-FERMENTED WHOLE RICE BRAN IN THE PRODUCTION OF THE ROTIFER Brachionus plicatilis

The objective of the present study was to evaluate the use of fermented and non-fermented whole rice bran for rotifer feeding, based on the effects on growth parameters, antioxidant and oxidative damage responses, and water quality. The study was based on three experiments, which compared the effect of different concentrations of non-fermented whole rice bran, the effect of different concentrations of fermented whole rice bran and the effect of the best concentrations of fermented and non-fermented whole rice bran, as well as the replacement of part of the baking yeast by rice bran. The results showed the best growth performances in treatments with 0.7 g yeast with 1.5 g fermented rice bran, 0.35 g yeast with 0.75 g whole rice bran, and 0.35 g yeast with 0.75 g fermented rice bran. Fermentation of rice bran for 6 hours did not induce oxidative stress in rotifers. This work revealed that the use of 1.5 g of fermented bran and replacement of 50% of yeast with fermented or non-fermented rice bran may be used for rotifer feeding, with the additional benefit of improving the environmental quality due to the lower amount of ammonia released in the water.
Unforeseen consequences of conservation management practices: case study on herding rhino as an anti‐poaching measure

The current biodiversity crisis calls for effective conservation measures. However, some measures may have unforeseen negative consequences on individual species. Herding, a management practice currently used in some wildlife species to protect animals from poachers, can cause habituation to humans, which unintentionally might increase their risk of being poached at a later time. Herding could also negatively impact animal welfare and physiology when perceived as a stressor, with potential negative consequences at the individual and population level. In this study, we tested the following hypotheses: 1) herding elicits habituation to humans in white rhino, and 2) this practice affects the behavior and physiological state of rhino, but they can habituate to it. To that aim, we investigated the effects of herding on the response of rhino to initially unfamiliar people, expression of aggressive and discomfort behaviors, and fecal glucocorticoid metabolite (fGCM) concentrations (a commonly used indicator of physiological stress) in two cohorts of six and 10 semi‐wild orphan white rhino. Rhino did not interrupt their activity to an approaching person on foot (99%) or in a vehicle (94%), indicating habituation to humans. Aggressive and discomfort behaviors were displayed more often while being herded, and their frequency increased significantly with increasing herding pressure. Finally, overall mean fGCM concentrations were 16.1% higher under herding compared to non‐herding conditions, but individual fGCM levels varied up to 17‐fold under each scenario, suggesting that herding might not elicit a physiological stress response in these animals. While rhino security is paramount in the current poaching crisis, management practices must ensure that they do not impact negatively at the individual and population level.