Miracle-dz/UniFAR-FTUs huggingface dataset:
Fast Seamless Handoff for Mobile Cloud Computing using Service-Oriented Architecture

: - Mobile devices are gaining in popularity and becoming the major platform for users to obtain cloud computing services at anytime and anywhere. Because of this demand, the cloud computing environment has been adapted into mobile technology by the addition of new prototypes and paradigms. From the perspective of mobile computing, the handoff process affects the Quality of Service (QoS) provisioning, reliability, and limits the mobile device’s life. Thus, it is significant to handle the handoff process efficiently and intelligently when accessing the cloud computing environment using a mobile device. This paper introduces the novel service-oriented architecture to support a new handoff process. The service oriented architecture consists of five layers: application layer, IP multimedia Subsystem (IMS) layer, communication layer, Media layer, and connectivity layer. The advantage of using service oriented architecture is that it makes it easy to access to the cloud contents and also helps in maintaining the QoS, reducing the bandwidth consumption and power consumption. This paper also introduces the fast seamless handoff for cloud computing that reduces the handover time. To validate the effectiveness of service oriented architecture for handling the different types of handoffs, we use the GreenCloud simulator that is an extension of network simulator-2 (NS2). The simulation results demonstrate that our fast seamless handoff (FSH) supported with service oriented architecture improves the data access reliability and reduces the power and bandwidth consumption. Furthermore, the performance of other well-known handoff processes is compared with our proposed FSH handoff. Based on the simulation result, our approach performs better.
Image Fusion and Recursive Filtering based Feature Extraction of the Hyperspectral Images

- Hyperspectral images obtained from hyperspectral satellite sensors have high resolution. This is because these images have several spectral bands for every pixel and hence they provide detailed information regarding the physical nature of the different materials. However, due to high dimensionality of hyperspectral data, a problem named as “Hughes phenomenon” arises. For such cases feature extraction is an effective way in reducing the dimensionality. Various feature selection and feature extraction methods are discussed. This paper deals with a simple method based on image fusion and recursive filtering (IFRF) to extract the features of the hyperspectral images. Firstly, the hyperspectral image is partitioned into multiple subsets of adjacent bands. These bands are then fused together by using the simplest fusion technique i.e. averaging. Lastly, the fused bands are processed with the transform domain recursive filtering to get the resulting IFRF features for classification.
Strain-Dependent Activity of Zika Virus and Exposure History in Serological Diagnostics

Zika virus (ZIKV) circulates as two separate lineages, with significant genetic variability between strains. Strain-dependent activity has been reported for dengue virus, herpes simplex virus and influenza. Strain-dependent activity of subject specimens to a virus could be an impediment to serological diagnosis and vaccine development. In order to determine whether ZIKV exhibits strain-dependent activity when exposed to antibodies, we measured the neutralizing properties of polyclonal serum and three monoclonal antibodies (ZKA185, 753(3)C10, and 4G2) against three strains of ZIKV (MR−766, PRVABC59, and R103454). Here, MR−766 was inhibited almost 60% less by ZKA185 than PRVABC59 and R103454 (p = 0.008). ZKA185 enhanced dengue 4 infection up to 50% (p = 0.0058). PRVABC59 was not inhibited by mAb 753(3)C10 while MR−766 and R103453 were inhibited up to 90% (p = 0.04 and 0.036, respectively). Patient serum, regardless of exposure history, neutralized MR−766 ~30%−40% better than PRVABC56 or R103454 (p = 0.005−0.00007). The most troubling finding was the significant neutralization of MR−766 by patients with no ZIKV exposure. We also evaluated ZIKV antibody cross reactivity with various flaviviruses and found that more patients developed cross-reactive antibodies to Japanese encephalitis virus than the dengue viruses. The data here show that serological diagnosis of ZIKV is complicated and that qualitative neutralization assays cannot discriminate between flaviviruses.
Induction of competent cells for Agrobacterium tumefaciens-mediated stable transformation of common bean (Phaseolus vulgaris L.)

Stable transformation of common bean (Phaseolus vulgaris L.) has been successful, to date, only using biolistic-mediated transformation and shoot regeneration from meristem-containing embryo axes. In this study, using precultured embryo axes, and optimal co-cultivation conditions resulted in a successful transformation of the common bean cultivar Olathe using Agrobacterium tumefaciens strain EHA105. Plant regeneration through somatic embryogenesis was attained through the preculture of embryo axes for 12 weeks using induced competent cells for A. tumefaciens-mediated gene delivery. Using A. tumefaciens at a low optical density (OD) of 0.1 at a wavelength of 600 nm for infection and 4-day co-cultivation, compared to OD600 of 0.5, increased the survival rate of the inoculated explants from 23% to 45%. Selection using 0.5 mg L-1 glufosinate (GS) was effective to identify transformed cells when the bialaphos resistance (bar) gene under the constitutive 35S promoter was used as a selectable marker. After an 18-week selection period, 1.5% -2.5% inoculated explants, in three experiments with a total of 600 explants, produced GS-resistant plants through somatic embryogenesis. The expression of bar was confirmed in first- and second-generation seedlings of the two lines through reverse polymerase chain reaction. Presence of the bar gene was verified through genome sequencing of two selected transgenic lines. The induction of regenerable, competent cells is key for the successful transformation, and the protocols described may be useful for future transformation of additional Phaseolus germplasm.
Difficult posteroseptal pathway ablation and recurrent PSVT

A 47-year-old man with hypertension, obesity, and palpitations presented for the evaluation of recurrent, paroxysmal supraventricular tachycardia (PSVT). He had two previous ablations for PSVT, at outside institutions, which were unsuccessful. This article is protected by copyright. All rights reserved.
Validation of a commercially available inertial measurement unit for recording jump load in youth basketball players

ABSTRACT A high incidence of overuse knee injuries among youth basketball players may be attributed to number of jumps. Wearable technology may be an effective tool for measuring jump load compared to traditional counting methods. The purpose of this study was to validate a commercially available jump counter (VERT® Classic) in youth basketball practices and games, and to identify the characteristics (i.e., height, direction, takeoff) of jumps recorded by the VERT® Classic. 46 (19F, 27M) youth basketball players wore a VERT® Classic and were recorded on video during games and practices. The number of jumps recorded by the VERT® Classic and evaluated by video raters were compared for each jump characteristic using intraclass correlation coefficient (ICC(3,k)), mean offset, and limits of agreement. The number and percent of VERT® Classic jumps and corresponding video jumps according to timestamp were reported. VERT® Classic jumps had excellent reliability with video-counted jumps over 15 cm (ICC(3,k) = 0.958), with a mean offset of −2.4 jumps (fewer VERT® Classic) and limits of agreement −12.6 to 7.8 jumps. Pairs of corresponding jumps represented 68.0% of total video jumps and 92.0% of VERT® Classic jumps. The VERT® Classic can provide an estimate of jump load in youth basketball.
Development of an automated AmpliSeq™ library building workflow for biological stain samples on the Biomek® 3000.

Here, we present the development of an automated AmpliSeq™ (ThermoFischer, MA, USA) workflow for library building using the Biomek® 3000 Laboratory Automation Workstation (Beckman Coulter Inc., CA, USA), in which the total volume of PCR reagents and reagents for library preparation are reduced by one-half. The automated AmpliSeq workflow was tested using 43 stain samples (blood, bone, muscle tissue, semen, swab, nail scrape and cigarette butts) collected from crime scenes. The sequencing data were evaluated for locus balance, heterozygous allele balance and noise. The performance of libraries built with the automated AmpliSeq workflow using one-half of the recommended reagent volumes were similar to the performance of libraries built with the recommended (full) volumes of the reagents.
Control of Peri-Implant Mucous Inflammation by Using Chlorhexidine or Ultraviolet C Radiation for Cleaning Healing Abutments. Double-Blind Randomized Clinical Trial

Two-phase implants must be exposed to the external environment after the period of osteointegration has elapsed. For this purpose, a healing abutment is placed passing through the mucosa while forming the emergence profile. The continuous connection and disconnection can lead to an alteration in the tissue maturation, both because of the contact of bacterial plaque and because of the mechanical trauma that involves its manipulation, manifesting with different degrees of erythema or bleeding. To assess whether this epithelium disruption can be counteracted, a blinded study design was developed on 150 unitary implant patients divided into three groups (n = 50), applying chlorhexidine (group 1), ultraviolet C (UV-C) at a wavelength of 254 nm (group 2)and no treatment as a control group (group 3), during each of the disconnections and connections during the prosthodontic treatment (1 time per week for four weeks). All groups showed a better epithelium aspect at the end of the evaluation. Although there were no statistically significant differences in the degree of inflammation, the UV-C treated group had the lowest plaque accumulation, and the highest was for the chlorhexidine-treated group.
Combining ibrutinib and checkpoint blockade improves CD8+ T-cell function and control of chronic lymphocytic leukemia in E-TCL1 mice

Ibrutinib is a Bruton’s tyrosine kinase (BTK) inhibitor approved for the treatment of multiple B-cell malignancies, including chronic lymphocytic leukemia (CLL). In addition to blocking B-cell receptor signaling and chemokine receptor-mediated pathways in CLL cells, that are known drivers of disease, ibrutinib also affects the microenvironment in CLL via targeting BTK in myeloid cells and IL-2–inducible T-cell kinase (ITK) in T cells. These non-BTK effects were suggested to contribute to the success of ibrutinib in CLL. By using the Eμ-TCL1 adoptive transfer mouse model of CLL, we observed that ibrutinib effectively controls leukemia development, but also results in significantly lower numbers of CD8+ effector T cells, with lower expression of activation markers, as well as impaired proliferation and effector function. Using CD8+ T cells from a T-cell receptor (TCR) reporter mouse, we verified that this is due to a direct effect of ibrutinib on TCR activity, and demonstrate that co-stimulation via CD28 overcomes these effects. Most interestingly, combination of ibrutinib with blocking antibodies targeting PD-1/PD-L1 axis in vivo improved CD8+ T-cell effector function and control of CLL. In summary, these data emphasize the strong immunomodulatory effects of ibrutinib and the therapeutic potential of its combination with immune checkpoint blockade in CLL.
Lower-body compression garments worn following exercise improves perceived recovery but not subsequent performance in basketball athletes

ABSTRACT This study examined the effects of lower-body compression garments on perceived recovery and subsequent performance in basketball athletes. In a parallel-group design, 30 recreational, male basketball athletes were randomly allocated to either a control (CON, n = 15, loose-fitting clothing) or experimental group (COMP, n = 15, compression garments) for 15 h following fatigue-inducing, basketball-specific exercise in the evening (1600-1800 h). Perceptual measures of fatigue and muscle soreness, as well as physical performance tests (sprints, jumps and agility), were performed pre-exercise, post-exercise, and post-recovery (15 h following exercise). Subjective and objective measures of sleep were recorded following the exercise trial. There were non-significant (p > 0.05), unclear-trivial differences between groups for all performance measures. Perceived post-recovery fatigue (d = −1.27, large) and muscle soreness (d = −1.61, large) were significantly lower in COMP compared to CON (p < 0.05). COMP exhibited better perceived sleep quality (d = 0.42, small, p = 0.18) than CON, with an unclear difference in sleep duration between groups (p > 0.05). Wearing lower-body compression garments overnight improved perceived fatigue and muscle soreness, but had negligible effects on subsequent physical performance in basketball athletes. Future research should focus on longer periods of compression wear following fatiguing exercise.
A Comprehensive Study on Significance of Image De-Noising and De-Blurring Applications in Computed Tomography

: De-noising and De-blurring is the technique that uses procedures to subsidize and remove the strange and useless content in the images De-noising and de-blurring is very beneficial for detecting the diseases like cancers, tumors in human body. But noise and Blur are the major factors that degrade the quality of images and makes difficult to diagnose. Reconstructing the images is the way to overcome these problems. This paper presents the study of various applications that are suitable to reconstruct the images. This survey mainly focuses on most prominent applications in the field of image processing and how its applications are critical enough to avoid dissatisfied results. The aim of this survey is to provide useful information on various de-blurring and de-noising applications and to motivate research to implement the effective algorithm.
LncRNA LUCAT1 promotes proliferation of ovarian cancer cells by regulating miR-199a-5p expression.

OBJECTIVE To investigate the biological effect of long non-coding ribonucleic acid (lncRNA) lung cancer-associated transcript 1 (LUCAT1) in the development of ovarian cancer. MATERIALS AND METHODS Real-time quantitative polymerase chain reaction (RT-qPCR) was utilized to detect the expression levels of lncRNA LUCAT1 in three human ovarian cancer cell lines (CaoV-3, SK-OV-3 and HO-8910) and the normal human ovarian surface epithelial cell line (IOSE80). Small interfering RNAs against lncRNA LUCAT1 (si-LUCAT1) were transfected into SK-OV-3 cells. Transfection efficiency of si-LUCAT1 was verified via RT-qPCR. Cell Counting Kit-8 (CCK-8) and colony formation assays were performed to test the effect of silencing lncRNA LUCAT1 on SK-OV-3 cell proliferation. The apoptosis was measured by flow cytometry. The miRcode database was searched to predict potential microRNAs (miRNAs) binding lncRNA LUCAT1. It was found that lncRNA LUCAT1 contained a highly conserved binding site of miR-199a-5p in the 3'-untranslated region (3'-UTR). Subsequently, the targeting relationship between them was determined through Dual-Luciferase reporter gene assay and RT-qPCR analysis. RESULTS LncRNA LUCAT1 was highly expressed in three human ovarian cancer cell lines compared to that in normal ovarian surface epithelial cell line (p<0.05). The cell proliferation rate in SK-OV-3 cells with lncRNA LUCAT1 knockdown was remarkably lower in comparison to that in control group. Moreover, colony formation assay also revealed that the number of cell clones decreased significantly after knockdown of lncRNA LUCAT1 compared to that in control group (p<0.05). In addition, the apoptosis rate was distinctly elevated in the lncRNA LUCAT1 silencing group (p<0.05). Furthermore, a highly conserved binding site of miR-199a-5p was found in the 3'-UTR of lncRNA LUCAT1. Dual-Luciferase reporter gene assay exhibited that the Luciferase activity of LUCAT1-wt was significantly reduced after overexpression of miR-199a-5p (p<0.05), while that of LUCAT1-mut was unchangeable. Further analysis via RT-qPCR suggested that miR-199a-5p overexpression significantly decreased the expression level of lncRNA LUCAT1 (p<0.05). CONCLUSIONS LncRNA LUCAT1 is overexpressed in ovarian cancer cells, which may target miR-199a-5p to exert its effects on driving the malignant development of ovarian cancer.
Disordered Eating Attitudes and Negative Automatic Thoughts Negatively Affect the Self-Esteem of Turkish High School Students

This study reports on therelationship between adolescents’ eating attitudes and self-esteem, automatic thoughts and some other variables. Participants consisted of 597 students from the 9, 10, 11 and 12 grades of 4 different Anatolian high schools selectedrandomly using the cluster sampling method. The mean age of adolescents was 16.45 years with a standard deviation of 1.14. Adolescents completed a questionnaire including the Personal Information Form, Coopersmith Self-Esteem Inventory, Automatic Thoughts Questionnaire and Eating Attitudes Test. Data was analysed using the SPSS program. In the study, there was a significant difference between girls and boysin terms of their Body Mass Indexvalues and self-esteem scores. There was also a significant difference between the students with ≥30 EAT scores and those with ≤ 29 EAT scores in terms of negative automatic thoughts and self-esteem levels. Thus, it is important to conductfurtherstudies to increase the self-esteem of adolescents, particularly those with negative automatic thoughts, and to help them adopt healthy eating habits. Increasing students’ self-esteem, introducing them to healthy eating behaviours and reducing their negative thoughts within the scope of guidance services may also be helpful.
21-Azman Bin Jais.cdr

61 International Education & Research Journal [IERJ] Introduction Educational revolution is now moving in tandem with the boom of information and communication technology. The transformation of teaching and learning methods (PDP) needs to be changed so that learning content is delivered more effective, accurate and efficient. In order to achieve developed nation status by 2020 as outlined in Vision 2020, Malaysia needs to adopt a first-class mind and have a high durability (Ministry of Education (MOE) 2006). In order to realize this agenda, Vision 2020 requires innovation in the educational curriculum to emphasize the application of methods, techniques and learning strategies, in particular the use of integrated Information and Communication Technology (ICT) as a reform in the context of teaching and learning, particularly, innovative webbased learning (Cavus&Momani 2009). Therefore, the government has created 1BestariNet involving 10, 000 primary and secondary schools, which are equipped with internet access and a world class Virtual Learning Environment (VLE) and will ensure that all teachers are competent in the use of the VLE by 2015 (Malaysia Education Blueprint -PPPM 2013 -2025).
Ice Melting Can Change DMSP Production and Photosynthetic Activity of the Haptophyte Phaeocystis antarctica1

Phaeocystis antarctica is an important primary producer in the Southern Ocean and plays roles in sulfur cycles through intracellular production of dimethylsulfoniopropionate (DMSP), a principal precursor of dimethyl sulfide (DMS). Haptophytes, including P. antarctica, are known to produce more DMSP than other phytoplankton groups such as diatoms and green algae, suggesting their important contribution to DMS concentrations in the Southern Ocean. We assessed how sea ice formation and melting affect photosynthesis and DMSP accumulation in P. antarctica both in seawater and in sea ice. Incubations were undertaken in an ice tank, which simulated sea ice formation and melting dynamics. The maximum quantum yield of photochemistry (Fv/Fm) in photosystem II, as estimated from pulse‐amplitude‐modulated (PAM) fluorometry, was generally higher under low‐light conditions than high‐light conditions. Values of Fv/Fm, the relative maximum electron rate (rETRmax), and photosynthetic efficiency (α) were lower in sea ice than in seawater, implying reduced photosynthetic function inside the sea ice. The reduction in photosynthetic function was probably due to the hypersaline environment in the brine channels. Total DMSP (DMSPt) concentration normalized by chlorophyll‐a concentration was significantly higher in the sea ice than in the other environments, suggesting high accumulation of DMSP, probably due to its osmotic properties. Fv/Fm, specific growth rate, and DMSPt concentrations decreased with decreasing salinity with the lowest values found at a salinity of 22, that is, the lowest salinity tested. These results suggest that sea ice melting is responsible for a reduction in growth rate and DMSP production of P. antarctica.
Sentiment Analysis Tool for Daily Speech Turkish Texts

— Sentiment analysis research area is going at a great pace and lot of work has been done. Many tools have been implemented which are helpful for English users but not for other languages. This paper is concerned about Turkish texts. Especially daily speech texts. Communication helps in analyzing the sentiments of people written in textual form by understanding people views that what they think about a particular thing. Sentimental analysis means to analyze people viewpoints, good or bad and their views can be taken from social websites, forums, etc. This paper discusses the implementation of sentiment analysis tool for daily speech Turkish texts which helps in extracting people thoughts. The process includes text normalization, stemming, n-gram analysis, matrix generation, different feature extraction methods and different classification algorithms. It shows great improvement for daily speech Turkish texts by the help of natural language processing methods.
The availability of an adhesive bone conduction hearing device: a preliminary report of a single-center experience

Abstract Background: An adhesively attached bone conduction hearing device has been newly developed. This novel bone conduction hearing device is placed behind the ear and has an audio processor connected to the adapter to transmit sound through vibrations. Objective: To obtain preliminary results regarding the use of this device, we sought to apply it to patients with various types of hearing loss. Methods: Nine patients aged over 18 years and with hearing loss due to bilateral middle ear anomaly (n = 1), bilateral aural atresia (n = 3), unilateral aural atresia (n = 2), and single-sided deafness (n = 3) were recruited. Results: The functional gain provided by the adhesive bone conduction hearing device for the aided side was found to be sufficient. Although the results on speech perception in noise showed significant improvement for patients with conductive hearing loss, no improvement was found for patients with single-sided deafness. Subjective assessment showed that speech and spatial hearing-related issues were improved. Conclusion: The adhesive bone conduction hearing device was thought to provide a feasible option. Additionally, in patients considering the use of a surgically implanted hearing device, this device is a preferable option for preoperative assessment due to its non-invasiveness.