Miracle-dz/UniFAR-FTUs huggingface dataset:
Rhabdomyolysis caused by carnitine palmitoyltransferase 2 deficiency: A case report and systematic review of the literature

Carnitine palmitoyltransferase 2 deficiency is an inherited metabolic disorder involving a deficiency in a mitochondrial enzyme necessary for long chain fatty acid oxidation, and therefore decreased utilisation of fatty acids. The adult form of this condition leads to recurrent rhabdomyolysis triggered by exercise, fasting and infection. It is a very rare condition with only a few hundred reported cases worldwide. Here we present a case of severe rhabdomyolysis in the context of carnitine palmitoyltransferase 2 deficiency in which major organ involvement was avoided, and organ support was not needed. This prompted us to perform a systematic review of the existing case reports in the literature to ascertain the most frequent patterns of organ involvement and assess the outcomes that are seen in these patients. Our findings suggest that these patients most frequently develop isolated renal failure, often requiring renal replacement therapy; however, the outcomes following this are very good, supporting the early involvement of intensive care teams.
Leaf gall polymorphism and molecular phylogeny of a new Bruggmanniella species (Diptera: Cecidomyiidae: Asphondyliini) associated with Litsea acuminata (Lauraceae) in Taiwan, with ecological comparisons and a species description

Two types of cecidomyiid leaf galls, cup‐shaped and umbrella‐shaped, occur on Litsea acuminata (Lauraceae) in Taiwan. Based on the concept of gall shapes as “extended phenotypes” of gall inducers, these two types could be induced by different gall midge species. However, galls with intermediate shapes between the two types were recently discovered, which implies that possible genetic exchanges occur between the gall inducers of both types. To clarify the taxonomic status of gall midges responsible for the two types of galls on L. acuminata, we undertook taxonomic, molecular phylogenetic and ecological studies. Our findings show that the two gall types are induced by the same Bruggmanniella species and the species is new to science. We describe the species forming this range of galls as Bruggmanniella litseae sp. n. , and compare their geographical distribution, galling position and morphometry. Based on our results, a possible evolutionary scenario of B. litseae sp. n. is discussed.
Achieving Zero-Packet-Loss Throughput 1 for a Collision Channel Without Feedback and With Arbitrary Time Offsets

The collision channel without feedback (CCw/oFB) introduced by Massey and Mathys, depicts a scenario where multiple users share a communication channel but have arbitrary time offsets, and can never learn these time offsets due to the lack of feedback. This paper considers an extension of the CCw/oFB, which allows the receiver to use successive interference cancellation (SIC) to cancel the interference caused by those collided packets whose contents have been known by the receiver. We derive the zero-packet-loss throughput regions of this model for both the unsynchronized and slot-synchronized cases. Given an arbitrary number of users and a packet alphabet of arbitrary size, it is shown that these two regions coincide, and the outer boundary of this common region is the set of all points with only nonnegative components that add up to one. It is further shown that all points on this outer boundary with only rational components can be achieved without packet loss in the slot-synchronized case. The constructive proofs are based on a joint design of protocol sequences, identification/location algorithm and erasure correcting codes. These findings indicate that the negative impact of the lack of time synchronization on the throughput performance can be removed by the help of SIC.
Molecular docking of the active compound Garcinia mangostana on the RANKL/RANK/OPG system

This study aims to analyze the molecular docking between the active compounds of the Garcinia mangostana against the RANKL/RANK/OPG system and its potential as an antiosteoporosis. The research protocol includes the search and modeling of protein and ligand structures and their docking. Software used includes OpenBabel, HEX 8.0, Chimera 1.6. 2, Discovery Studio 4.1, LigPlot + and LigandScout 3.1. Tovophillin has the most negative interaction energy with RANKL-OPG (−332.8 Kj/mol) and RANKL-RANK (−298.1 Kj/mol). It was concluded that fourteen active compounds of Garcinia mangostana did not interfere with the physiological function of RANKL against RANK. In addition, the active compound will not affect the RANKL-OPG complex. The antiosteoporosis mechanism of Garcinia mangostana does not by inhibiting RANKL-RANK interactions.
Relationship Between Parameters of Development and Functional Compounds of Yacon Leaves

Yacon is a tuberous root from the Andean region being increasingly grown across the world due to the low caloric values of their roots and the functional properties of extractions of its leaves. However, there is still a gap in the knowledge of how the plant develops, and if physical and chemical changes are noticed regarding maturity. The subject of this work was to investigate the dynamics of a group of parameters and to establish correlations across them. To achieve this goal, leaves collected from three different parts of the plant in three months were assessed regarding size (plant height and leaf area), color and the presence of sesquiterpene lactones. Different methods of extraction were also HIGHLIGHTS • Yacon leaves at the apical and middle of the plant present higher phenolic content. • Phenolic content showed correlations with the greenness of the leaves. • The decoction of yacon leaves can extract more phenolics than the infusion. 2 Ferreira, B.M. R. ; et al. Brazilian Archives of Biology and Technology. Vol.62: e19180439, 2019 www.scielo. br/babt studied and the total phenolic content was analyzed. The analysis of the results revealed different patterns in the quantity, size and leaf distribution according to the age of the plant. From three different methods of extraction studied, decoction seems to be the most appropriate one to obtain phenolic compounds with greater yield and safety. Besides, the greenness of yacon leaves showed a linear correlation to the total phenolic content, being a simple and promising estimator of the corresponding bioactive group. Sesquiterpene lactones were identified in all extracts, indicating the ease of their extractability even in simple procedures of tea-making.
Self-Triggering High-Frequency Nanosecond Pulse Generator

With the increasingly extensive and in-depth applications of all solid-state high-voltage nanosecond pulse generators in the defense and industrial fields, the development of traditional pulse generators faces many key issues, such as high-voltage drive isolation, compact design, and reduced weight. Hence, a novel circuit topology for a self-triggered high-frequency nanosecond pulse generator is proposed. Through high potential energy-gaining technology of the interstage capacitance, this generator does not need a complicated metal–oxide–semiconductor field-effect transistor isolation drive circuit, and there are also no switching dynamic and static voltage equalization problems. This kind of generator is very suitable for compact assembly with only a single external gate driver. High voltage output can be realized by quantizing multilevel module stacking according to actual needs. At the same time, the generator has a high repetition rate and long life. The characteristic parameters of the 20-stage superposition experimental prototype are as follows: an output voltage amplitude of 15.3 kV with a rising time of approximately 45 ns, a repetition rate of 10 kHz in the pulse train, and a pulsewidth of 200–1000 ns.
Screening of AM Fungi based on Peroxidase Activity under Irrigation Regime of -500kPa in Soybean (Glycine max L. Merill)

Moisture stress is a serious problem in India. The severity and the extent of moisture stress not only depend on low rainfall but also on the other hydro-meteorological factors like infiltration and moisture retention capacity of the soil. Aridity of an area depends on rainfall in relation to potential or actual evapotranspiration and the moisture holding capacity of the soil. Potential evaporation is a measure of the maximum possible evaporation from the soil and the transpiration from vegetation, if the soil is fully saturated. It is a measure of consumptive use of water by crops.
Experiências de cuidado dos enfermeiros às pessoas com hanseníase: contribuições da hermenêutica

Resumo Objetivo Estudo qualitativo fundamentado na hermeneutica filosofica que teve como objetivo analisar a experiencia de cuidar de pessoas com hanseniase na pratica de enfermeiros do Municipio do Rio de Janeiro. Metodos Estudo qualitativo desenvolvido nas areas programaticas de saude do municipio do Rio de Janeiro, que apresentaram alto ou medio coeficiente de deteccao de hanseniase em 2014. Foram selecionados servicos com os seguintes perfis: exclusivamente ESF, servicos com clinicas especializadas e unidades mistas que se caracterizam pela coexistencia da [. ]
Questions in Development

Everyone will likely acknowledge that attitudes such as curiosity and interest are vitally important for learning, and that young children ask so many questions because they are intensely curious and interested in the world around them. But the nature of these questioning attitudes themselves is poorly understood. Indeed, many have a mistaken view of them – or so I will claim. In consequence, many are led to give mistaken accounts of the cognitive processes that underlie children’s asking and answering of questions, too. This matters, both for our understanding of childhood development generally and for designing interventions that are intended to help children learn. This chapter has two main goals. One is to offer a fresh set of conceptual resources for those wanting to understand childhood development – specifically, the likely existence from infancy of a set of first-order, non-metacognitive, questioning attitudes. The second is to suggest that the early question-asking and question-answering behavior of infants and toddlers is best understood as expressive of such attitudes, rather than providing evidence of early metacognition. (Metacognition is defined as cognition that is about cognition, or “thinking about thinking,” and the term is generally restricted to cases where one thinks about one’s own thoughts, rather than the thoughts of other people; see Flavell, 1979; Nelson & Narens, 1990; Dunlosky & Metcalfe, 2009.) People can ask questions for instrumental reasons (“Where are the car keys? ”), but often they are just curious (“Why do birds sing? ”). And almost all philosophers and cognitive scientists who have written on the topic of curiosity have addressed it in metacognitive terms – as involving a desire for knowledge or true belief, or as an intrinsic motivation to learn, or something of the sort. (See Foley, 1987; Goldman, 1999; and
Effect of foot care health training towards nurses and health volunteers ability in performing foot care on diabetes in Batua Health Center, Makassar

Foot care is one of the management for diabetes mellitus that is important to prevent diabetes ulcers. Studies have proven that people with diabetes will have a lower risk of having diabetes ulcer if they have received health education about foot care to prevent diabetes ulcers Thus, health education is considered very important to help people with diabetes preventing foot ulcer. Health care provider including health professionals and health volunteers should provide health education regularly to the patient, however, due to their workload preventing them from providing this intervention to the patient as well as a lack of knowledge about foot care. Based on the initial interview with diabetes program staff, the health education program is not implemented well yet and they need specific training about foot care for nurses, health volunteers and patients. The aim of this study is to see the effect of foot care health training towards nurses and health volunteers ability performing foot care on diabetes. This study used pre-experimental with pre-test and post-test one-group design to 30 respondents (23 health volunteers and 7 nurses from Puskesmas Batua Makassar). The training was given the research team, and after training, there was follow-up training (two times) where the research team accompanied the respondents to provide foot care to the patients which was assessed through a questionnaire. Data were analysed using the paired t-test.This study found there is an improvement in ability in conducting diabetes foot care among the participants the average before treatment(x = 17.93, SD = 1.363) to (x = 19.37, SD = 0.718) after training. This study has proven the effect of training to improve nurses and health volunteers ability in performing foot care on diabetes patient. Thus, it is recommeded that nurses and health volunteers regularly providing health education related to foot care for diabetes patients to prevent foot ulcer such as including it in Prolanis health education program.
Capuchin (Sapajus [Cebus] apella) Change Detection

Change blindness is a phenomenon in which individuals fail to detect seemingly obvious changes in their visual fields. Like humans, several animal species have also been shown to exhibit change blindness; however, no species of New World monkey has been tested to date. Nine capuchins (Sapajus [Cebus] apella) were trained to select whether or not a stimulus changed on a computerized task. In four phases of testing, consisting of full image changes, subtle occlusion changes, and two levels of feature location changes, the search display and mask durations were systematically varied to determine whether capuchins experienced change blindness and in what contexts. Only the full image change test yielded significant results, with subjects detecting changes most accurately with longer search displays and, perplexingly, least accurately when there was no mask. No interactions between search display and mask durations were found in any test phase, suggesting that the relationship between the two parameters may not be important to how capuchins perceive changes. While it is possible that capuchins do not experience change blindness, we suspect that a mix of experimental design, the difficulty of the task, and the inability to verify how closely the subjects attended to each trial contributed to the lack of significant results
Aerobic capacity, physical activity and pain in adult victims of moderate to severe burns after discharge

Burns cause different impacts on the individual life. Many are the problems faced by survivors, such as hypermetabolism that may persist years after the event. The aim was to assess aerobic capacity, level of physical activity and pain in adult burn victims after hospital discharge. This is a descriptive, cross-sectional study. Participants (n = 60) were adult victims of moderate to severe burns, evaluated by six-minute walk test (6MWT), Pain Scale and International Physical Activity Questionnaire (IPAQ). We applied Student’s t-test for independent samples and Mann-Whitney test for comparisons between medium and large burned; Chi-square test to compare the level of physical activity. Large burned (73%) patients prevailed among the 60 participants; there was a statistically significant trend in the distance predicted between groups (p = 0.066), with no change in performance of the aerobic capacity. 60% reported physical activity practice at least three times a week: walking, cycling and soccer. As for the level of pain, 40% reported moderate to severe persistent pain, even after complete healing of wounds. Most participants showed aerobic capacity within the normal range, despite the high body mass index reported, they reported doing physical activities of moderate intensity.
A New Reference for the Thermal Equation of State of Iron

The high-pressure, high-temperature behavior of iron was investigated to 140 GPa and 3500 K with in situ synchrotron X-ray diffraction. Iron samples were compressed in diamond-anvil cells and heated up with the double-sided laser-heating system installed at the high-pressure ID27 of the European Synchrotron Radiation Facility (ESRF). Three different structures, namely α-bcc, γ-fcc or ε-hcp Fe were identified as a function of pressure and temperature in the domain we explored. At pressures above 90 GPa, it is clearly shown that ε-iron is the single stable solid phase up to 160 GPa at high temperatures. The analysis of the P-V-T relationship allows us to propose a reliable experimental thermal equation of state (EoS) for iron. We also show that the addition of low pressure points to our EoS refinement yields more robust constrain on the determination of the reference volume V0 of the ε-hcp structure, which has important implications on the final parametrization of the equation of state. The extrapolation of the proposed EoS to core pressure conditions indicates that a pure iron core would have an excess of density of 3% compared to the PREM density profile.
Multi-orientation analysis of retinal images for computer-aided diagnosis

Left-invariant PDE-evolutions on the roto-translation group SE(2) (and their resolvent equations) have been widely studied in the fields of cortical modeling and image analysis. They include hypo-elliptic diffusion (for contour enhancement) proposed by Citti & Sarti, and Petitot, and they include the direction process (for contour completion) proposed by Mumford. This chapter presents a thorough study and comparison of the many numerical approaches, which, remarkably, is missing in the literature. Existing numerical approaches can be classified into 3 categories: Finite difference methods, Fourier based methods (equivalent to SE(2)-Fourier methods), and stochastic methods (Monte Carlo simulations). There are also 3 types of exact solutions to the PDE-evolutions that were derived explicitly (in the spatial Fourier domain) in previous works by Duits and van Almsick in 2005. We provide an overview of these 3 types of exact solutions and explain how they relate to each of the 3 numerical approaches. We compute relative errors of all numerical approaches to the exact solutions, and the Fourier based methods show us the best performance with smallest relative errors. We also provide an improvement of Mathematica algorithms for evaluating Mathieu-functions, crucial in implementations of the exact solutions. Furthermore, we include an asymptotical analysis of the singularities within the kernels and we propose a probabilistic extension of underlying stochastic processes that overcomes the singular behavior in the origin of time-integrated kernels.
Interaction motifs variability in a Mediterranean palm under environmental disturbances: the mutualism–antagonism continuum

The nature and the strength of plant–frugivore interactions often vary along an antagonism–mutualism continuum and are highly influenced by the local ecological context (e.g. level of environmental disturbances). However, little is known concerning how the local ecological setting where plant–frugivore interactions take place affects the seed dispersal effectiveness (SDE) and, eventually, plant recruitment. This knowledge gap relates to the scarcity of empirical investigations on individual‐based plant–frugivore networks. We assessed whether the assembly of interaction modes (antagonist and mutualist) of the dwarf palm Chamaerops humilis (Arecaeae) affect the individual and the population level SDE in two Mediterranean sites differing in perturbation levels. We analysed the frequency distribution of interaction typologies and test its relationship with variation among individual palms in SDE. Additionally, we document how variation in interaction motif frequency (e.g. overrepresented interaction typologies) relates to changes in the SDE landscape of both disturbed study sites. We found that the interaction typologies of individual palms and its frugivores did not occur randomly. In a more complex landscape, interactions were more diverse and less dominated by simpler typologies, which may increase the stability of the plant–disperser interaction over the long term. We demonstrate that plants that interact with a more complex assemblage of frugivores, including both mutualistic and antagonistic partners, had the highest probability of recruitment. We found that the highly variable SDE among individual palms resulted from a few interaction modes occurring at higher than expected frequencies. We suggest this may be a reasonably frequent situation in diversified frugivore assemblages with a high heterogeneity of functional effects among mutualistic and antagonistic partners.
Data analytics for network intrusion detection

ABSTRACT A network intrusion can be any unauthorized activity on a network and network intrusion detection is a significant topic in cybersecurity. Data analytics is conducted on the database ‘spambase’ as an example of analysis for network intrusion detection based on the Naïve Bayesian classification, deep learning with the algorithm of Rprop+ and the hidden Markov model (HMM), respectively. All the analysis is fulfilled using R language and its functions. An HMM based on the Baum–Welch algorithm has been created on the database ‘spambase’ through training and parameter estimation. An HMM-based spam-email prediction has been performed through the probability evaluation based on the forward algorithm. The analytics results obtained from the above three methods are compared. It is shown that HMM-based analytics can achieve the best accuracy in the spam-email classification although only a few features are used in the HMM while all features are used in the Naïve Bayesian classification and deep learning.