Miracle-dz/UniFAR-FTUs huggingface dataset:
User Profiling from Reviews for Accurate Time-Based Recommendations

Recommender systems are a valuable way to engage users in a system, increase participation and show them resources they may not have found otherwise. One significant challenge is that user interests may change over time and certain items have an inherently temporal aspect. As a result, a recommender system should try and take into account the time-dependant user-item relationships. However, temporal aspects of a user profile may not always be explicitly available and so we may need to infer this information from available resources. Product reviews on sites, such as Amazon, represent a valuable data source to understand why someone bought an item and potentially who the item is for. This information can then be used to construct a dynamic user profile. In this paper, we demonstrate utilising reviews to extract temporal information to infer the \textit{age category preference} of users, and leverage this feature to generate time-dependent recommendations. Given the predictable and yet shifting nature of age and time, we show that, recommendations generated using this dynamic aspect lead to higher accuracy compared with techniques from state of art. Mining temporally related content in reviews can enable the recommender to go beyond finding similar items or users to potentially predict a future need of a user.
Real-time Universal Style Transfer on High-resolution Images via Zero-channel Pruning

Extracting effective deep features to represent content and style information is the key to universal style transfer. Most existing algorithms use VGG19 as the feature extractor, which incurs a high computational cost and impedes real-time style transfer on high-resolution images. In this work, we propose a lightweight alternative architecture - ArtNet, which is based on GoogLeNet, and later pruned by a novel channel pruning method named Zero-channel Pruning specially designed for style transfer approaches. Besides, we propose a theoretically sound sandwich swap transform (S2) module to transfer deep features, which can create a pleasing holistic appearance and good local textures with an improved content preservation ability. By using ArtNet and S2, our method is 2.3 to 107.4 times faster than state-of-the-art approaches. The comprehensive experiments demonstrate that ArtNet can achieve universal, real-time, and high-quality style transfer on high-resolution images simultaneously, (68.03 FPS on 512 times 512 images).
Direct Vlasov solvers

In these proceedings we will describe the theory and practical steps required to build Vlasov solvers such as those commonly used to compute coherent instabilities in synchrotrons. Thanks to a Hamiltonian formalism, we will derive a compact and general form of the linearized Vlasov equation, written using Poisson brackets. This in turn will be the basis of a procedure to build Vlasov solvers, applied to the specific example of transverse instabilities arising from beam coupling impedance.
Evidence for a Rotational Component in the Circumgalactic Medium of Nearby Galaxies

We present results of a study comparing the relative velocity of Lyα absorbers to the rotation velocity of nearby galaxy disks in the local universe (z ≤ 0.03). We have obtained rotation curves via long-slit spectroscopy of eight galaxies with the Southern African Large Telescope, and combine this data set with an additional 16 galaxies with data from the literature. Each galaxy appears within 3Rvir of a QSO sightline with archival Cosmic Origin Spectrograph spectra. We study the velocity orientation of absorbers with respect to nearby galaxy’s rotation, and compare with results from both the Steidel et al. monolithic halo model and a new cylindrical Navarro–Frenk–White galaxy halo model to interpret these data in the context of probing 3D galaxy halos via 1D QSO absorption-line spectroscopy. Relative to these models, we find that up to 59% ± 5% of Lyα absorbers have velocities consistent with corotation. We find the Lyα corotation fraction to decrease with galaxy luminosity (L*) and impact parameter in a model-independent fashion. We report that both anti-rotating absorbers and those found near luminous galaxies (L ≳ 0.5L*) mostly have low Doppler b-parameters (b ≲ 50 km s−1). Absorbers consistent with corotation show a wide range of Doppler b-parameters. Finally, we find a strong anticorrelation between corotation fraction and galaxy inclination, which is at odds with recent metal-line kinematic studies and suggests the kinematic and geometric distribution of the circumgalactic medium is complex and multiphase.
ESL: Entropy-guided Self-supervised Learning for Domain Adaptation in Semantic Segmentation

While fully-supervised deep learning yields good models for urban scene semantic segmentation, these models struggle to generalize to new environments with different lighting or weather conditions for instance. In addition, producing the extensive pixel-level annotations that the task requires comes at a great cost. Unsupervised domain adaptation (UDA) is one approach that tries to address these issues in order to make such systems more scalable. In particular, self-supervised learning (SSL) has recently become an effective strategy for UDA in semantic segmentation. At the core of such methods lies `pseudo-labeling', that is, the practice of assigning high-confident class predictions as pseudo-labels, subsequently used as true labels, for target data. To collect pseudo-labels, previous works often rely on the highest softmax score, which we here argue as an unfavorable confidence measurement. In this work, we propose Entropy-guided Self-supervised Learning (ESL), leveraging entropy as the confidence indicator for producing more accurate pseudo-labels. On different UDA benchmarks, ESL consistently outperforms strong SSL baselines and achieves state-of-the-art results.
DSDANet: Deep Siamese Domain Adaptation Convolutional Neural Network for Cross-domain Change Detection

Change detection (CD) is one of the most vital applications in remote sensing. Recently, deep learning has achieved promising performance in the CD task. However, the deep models are task-specific and CD data set bias often exists, hence it is inevitable that deep CD models would suffer degraded performance after transferring it from original CD data set to new ones, making manually label numerous samples in the new data set unavoidable, which costs a large amount of time and human labor. How to learn a transferable CD model in the data set with enough labeled data (original domain) but can well detect changes in another data set without labeled data (target domain)? This is defined as the cross-domain change detection problem. In this paper, we propose a novel deep siamese domain adaptation convolutional neural network (DSDANet) architecture for cross-domain CD. In DSDANet, a siamese convolutional neural network first extracts spatial-spectral features from multi-temporal images. Then, through multi-kernel maximum mean discrepancy (MK-MMD), the learned feature representation is embedded into a reproducing kernel Hilbert space (RKHS), in which the distribution of two domains can be explicitly matched. By optimizing the network parameters and kernel coefficients with the source labeled data and target unlabeled data, DSDANet can learn transferrable feature representation that can bridge the discrepancy between two domains. To the best of our knowledge, it is the first time that such a domain adaptation-based deep network is proposed for CD. The theoretical analysis and experimental results demonstrate the effectiveness and potential of the proposed method.
Note on Quantum Periods and a TBA System

There is an interesting relation between the quantum periods on a certain limit of local $\mathbb{P}^1\times \mathbb{P}^1$ Calabi-Yau space and a TBA (Thermodynamic Bethe Ansatz) system appeared in the studies of ABJM (Aharony-Bergman-Jafferis-Maldacena) theory. We propose a one-parameter generalization of the relation. Furthermore, we derive the differential operators for quantum periods and the TBA system in various limits of the generalized relation.
Magnetic droplet solitons

Magnetic droplet solitons are dynamical magnetic textures that form due to an attractive interaction between spin waves in thin films with perpendicular magnetic anisotropy. Spin currents and the spin torques associated with these currents enable their formation as they provide a means to excite non-equilibrium spin-wave populations and compensate their decay. Recent years have seen rapid advances in experiments that realize and study magnetic droplets. Important advances include the first direct x-ray images of droplets, determination of their threshold and sustaining currents, measurement of their generation and annihilation time, and evidence for drift instabilities, which can limit their lifetime. This perspective discusses these studies and contrasts these solitons to other types of spin-current excitations, such as spin-wave bullets, and static magnetic textures, including magnetic vortices and skyrmions. Magnetic droplet solitons can also serve as current controlled microwave frequency oscillators with potential applications in neuromorphic chips as nonlinear oscillators with memory.
Overexpression of GAS6 Promotes Cell Proliferation and Invasion in Bladder Cancer by Activation of the PI3K/AKT Pathway

Background Growth arrest-specific 6 (GAS6) is a secreted vitamin K-dependent protein abnormally expressed in various human tumor tissues and can activate the receptor Tyro3, Axl, and Mer to promote cancer cell proliferation and invasion. Until now, the role of GAS6 has been poorly understood in bladder cancer (BCa). Materials and Methods Using bioinformatics analysis, we screened genes significantly associated with overall survival in BCa. The association between GAS6 and survival was evaluated by tissue microarray and IHC staining. We investigated the effect of GAS6 on the development of BCa through in vitro and in vivo experiments. Results Here, we report that GAS6 is highly expressed in bladder cancer and is significantly associated with tumor grade, T stage, and worse prognosis. We found that GAS6 depletion inhibited proliferation, migration, and invasion of BCa cells. In addition, bioinformatics analysis revealed that GAS6 may be involved in the regulation of PI3K-AKT signaling pathway by binding to receptor TAM and has a significant positive correlation with PI3K family gene expression. Furthermore, Western blot experiments have shown that GAS6 might modulate the PI3K-AKT signaling to regulate proliferation and invasion of BCa cells. Treatment of BCa cells with SC79, an AKT activator, partially restored the effect of GAS6 silencing on cell proliferation and invasion. Conclusion The present study suggests that GAS6 may play a pivotal role in the development of BCa and may be a potential target for its treatment.
Sarcopenia: Influence of Regional Skeletal Muscle Cutoff Points and Fat-Free Mass in Older Mexican People—A Pilot Study

Background Variation in the prevalence of sarcopenia is related to the skeletal muscle index cutoff points applied. The objective of this pilot study was to examine the recruitment process for testing different sarcopenia definitions (ASMI cutoffs) in older Mexican adults. It explored whether the prevalence of sarcopenia decreased by applying ethnic- and gender-specific, DXA-derived appendicular skeletal muscle index (ASMI)-cutoff points in the definitions, as well as some associated factors in a sample of community-dwelling older Mexican people. Methods This is a pilot feasibility study that included a convenience sample of 217 community-dwelling older adults. Volunteers underwent DXA measurements and an assessment of functional status based on hand grip strength and physical performance. Six definitions were formed based on the 2010 EWGSOP criteria, but using different cutoff points for each of the three components, including regional cutoff points for ASMI derived from young Mexican adults. Several risk factors for sarcopenia were also assessed. Results The prevalence of sarcopenia varied according to the different definitions applied. The lowest level was found with the definition that applied regional ASMI-cutoff points (p < 0.01). The sarcopenic older adults had significant lower body weight, fat mass, and fat-free mass (FFM) than the nonsarcopenic subjects. The risk of sarcopenia increased with age and low FFM (p < 0.001). Conclusion The present study demonstrates the feasibility of the main study, and our data support the notion that using regional ASMI cutoff points resulted in a low prevalence of sarcopenia. Therefore, it is preferable to estimate the prevalence of this condition using ethnic- and gender-specific cutoff points and to explore associated factors such as low FFM.
Acute Cytokine Response During Breast Cancer Surgery: Potential Role of Dexamethasone and Lidocaine and Relationship with Postoperative Pain and Complications – Analysis of Three Pooled Pilot Randomized Controlled Trials

Purpose An imbalance in perioperative cytokine response may cause acute pain and postoperative complications. Anesthetic drugs modulate this cytokine response, but their role in non-major breast cancer surgery is unclear. In an exploratory study, we investigated whether intravenous lidocaine and dexamethasone could modulate the cytokine response into an anti-inflammatory direction. We also evaluated interrelationships between cytokine levels, pain scores and postoperative complications. Our goal is to develop multimodal analgesia regimens optimizing outcome after breast cancer surgery. Patients and Methods Forty-eight patients undergoing a lumpectomy were randomly assigned to placebo or lidocaine (1.5 mg⋅kg−1 followed by 2 mg⋅kg−1⋅hour−1) supplemented by dexamethasone zero, 4 or 8 mg, yielding six groups of eight patients. Interleukin (IL)-1β, IL-1Ra, IL-6, IL-10 levels and pain scores were measured at baseline and four hours postoperatively. We assessed postoperative complications occurring within 30 days. We noted persistent pain and infections as potential immune-related complications (PIRC). We used multiple regression to disentangle the effects of the individual study drugs (given by their partial regression coefficients (b)). Odds ratios (OR) estimated the link between pain scores and complications. Results Dexamethasone 8 mg increased IL-10 (b=12.70 (95% CI=8.06–17.34), P<0.001). Dexamethasone 4 mg and 8 mg decreased the ratio IL-6/IL-10 (b=−2.60 (−3.93 to −1.26), P<0.001 and b=−3.59 (−5.04 to −2.13), P<0.001, respectively). We could not show modulatory effects of lidocaine on cytokines. High pain scores were linked to the occurrence of PIRC’s (OR=2.028 (1.134–3.628), P=0.017). Cytokine levels were not related either to acute pain or PIRC. Conclusion Dexamethasone modulated the perioperative cytokine response into an anti-inflammatory direction. An overall lidocaine effect was not found. Patients with higher pain scores suffered from more 30-day PIRCs. Cytokine levels were not associated with pain or more postoperative complications, even not with PIRC. Larger studies in breast cancer surgery are needed to confirm these explorative results.
Surgical treatment of insertional Achilles tendinopathy: results after removal of the subcutaneous bursa alone—a case series

Background Insertional Achilles tendinopathy is well known to be difficult to treat, especially when there is intra-tendinous bone pathology. This study is a case series on patients with chronic insertional Achilles tendon pain and major intra-tendinous bony pathology together with bursa and tendon pathology, treated with excision of the subcutaneous bursa alone. Methods Eleven patients (eight men and three women) with a mean age of 44 years (range 24–62) and a chronic (>6 months) painful condition from altogether 15 Achilles tendon insertions were included. In all patients, ultrasound examination showed intra-tendinous bone pathology together with pathology in the tendon and subcutaneous bursa, and all were surgically treated with an open excision of the whole subcutaneous bursa alone. This was followed by full weight-bearing walking in a shoe with open heel for 6 weeks. Results At follow-up 21 (median, range 12–108) months after surgery, 9/11 patients (12/15 tendons) were satisfied with the result of the operation and 10/11 (13/15 tendons) were back in their previous sport and recreational activities. The median VISA-A score had improved from 41 (range 0–52) to 91 (range 33–100) (p<0.01). Conclusion In patients with chronic painful insertional Achilles tendinopathy with intra-tendinous bone pathology, tendon and bursa pathology, open removal of the subcutaneous bursa alone can relieve the pain and allow for Achilles tendon loading activities. The results in this case series highlight the need for more studies on the pain mechanisms in insertional Achilles tendinopathy and the need for randomised studies to strengthen the conclusions. Level of evidence IV Case series.
Reference value for the six-minute peg board and ring test. A cross sectional study

Introduction In our daily life, arm activities, whether supported or unsupported play a major role. Both simple and complex activities require the muscles, namely trapezius, pectoralis minor, scalene, and intercostals, to participate in arm positioning. These muscles also enact as the accessory respiratory muscles. Therefore, arm elevation increases the load on these muscles and they fail to perform dual activities, resulting in arm fatigue and a feeling of dyspnoea in healthy individuals as well as in chronic obstructive pulmonary disease patients. Various upper limb exercise tests were designed to measure this impairment, one of them being the six-minute peg board and ring test. The aim of the study is to derive a reference value for the six-minute peg board and ring test among healthy Indian population (Mangalore) from the age of 20-70 years of either gender. Also, to find a correlation among the number of rings and body mass index, arm length, arm and forearm circumference, the strength of shoulder and elbow flexors-extensors, grip strength of both sides and level of physical activity. Methods Participants performed two tests, thirty minutes apart. They were asked to load as many rings as possible in 6 minutes. Arm length, arm and forearm circumference were measured with a measuring tape. Shoulder and elbow flexors-extensors were assessed using a handheld push-pull dynamometer. Grip strength was measured with the Jamar hand-held dynamometer. Level of physical activity was assessed using International Physical Activity Questionnairelong form. Results The samples consisted of 450 healthy individuals between the age of 20-70 years. Reference values for each age group for both genders were reported. We found that age was correlated with the six-minute peg board and ring test score (p<0.05). We also found a correlation between the strength variables and the test results (p=0.001). However, no correlation was found between the arm length, arm and forearm circumference and the level of physical activity with the number of rings. Conclusion In this study, we derived a reference value for the six-minute peg board and ring test. There was a correlation among age, strength variables and the number of rings.
Screening and identification of key biomarkers for retinoblastoma

Abstract Background: Retinoblastoma (RB) is one of the most common malignant tumors in pediatrics; to clarify the cause of RB, a lot of manpower and material resources have been invested but have not been well explained. Methods: To identify the candidate genes in the occurrence and development of the disease, we downloaded the microarray datasets GSE97508, GSE92987, and GSE24673 from the gene expression database (GEO). The differentially expressed gene (DEG) was identified and functional enrichment analysis was performed. The protein–protein interaction network was constructed and analyzed by String and Cytoscape. Results: A total of 74 DEGs were identified, including 40 up-regulated genes and 34 down-regulated genes. The rich functions and pathways of DEG include regulating mitosis, cell cycle, DNA transcription process, promoting protein phosphorylation, regulating energy metabolism in vivo, promoting the binding of some macromolecular complexes, and regulating the cell cycle. Twenty-four HUB genes were identified. Biological process analysis showed that these genes were mainly enriched in regulating energy metabolism in vivo, promoting the binding of some small molecules and regulating the cell cycle. Survival analysis showed that DGPDC1, NDC80, SHCBP, TOP2A, and DLGAP5 may be involved in the occurrence, invasion, or recurrence of RB. Conclusion: In conclusion, screening DEGs and HUB genes in RB can help us to better understand the mechanism of the occurrence and development of RB at the molecular level, and provide candidate targets for the diagnosis and treatment of RB.
Multiple phenotypes conferred by a single insect symbiont are independent

Many microbial symbionts have multiple phenotypic consequences for their animal hosts. However, the ways in which different symbiont-mediated phenotypes combine to affect fitness are not well understood. We investigated whether there are correlations between different symbiont-mediated phenotypes. We used the symbiont Spiroplasma, a striking example of a bacterial symbiont conferring diverse phenotypes on insect hosts. We took 11 strains of Spiroplasma infecting pea aphids (Acyrthosiphon pisum) and assessed their ability to provide protection against the fungal pathogen Pandora neoaphidis and the parasitoids Aphidius ervi and Praon volucre. We also assessed effects on male offspring production for five of the Spiroplasma strains. All but one of the Spiroplasma strains provided very strong protection against the parasitoid P. volucre. As previously reported, variable protection against P. neoaphidis and A. ervi was also present; male-killing was likewise a variable phenotype. We find no evidence of any correlation, positive or negative, between the different phenotypes, nor was there any evidence of an effect of symbiont phylogeny on protective phenotype. We conclude that multiple symbiont-mediated phenotypes can evolve independently from one another without trade-offs between them.
The latitudinal diversity gradient of tetrapods across the Permo-Triassic mass extinction and recovery interval

The decline in species richness from the equator to the poles is referred to as the latitudinal diversity gradient (LDG). Higher equatorial diversity has been recognized for over 200 years, but the consistency of this pattern in deep time remains uncertain. Examination of spatial biodiversity patterns in the past across different global climate regimes and continental configurations can reveal how LDGs have varied over Earth history and potentially differentiate between suggested causal mechanisms. The Late Permian–Middle Triassic represents an ideal time interval for study, because it is characterized by large-scale volcanic episodes, extreme greenhouse temperatures and the most severe mass extinction event in Earth history. We examined terrestrial and marine tetrapod spatial biodiversity patterns using a database of global tetrapod occurrences. Terrestrial tetrapods exhibit a bimodal richness distribution throughout the Late Permian–Middle Triassic, with peaks in the northern low latitudes and southern mid-latitudes around 20–40° N and 60° S, respectively. Marine reptile fossils are known almost exclusively from the Northern Hemisphere in the Early and Middle Triassic, with highest diversity around 20° N. Reconstructed terrestrial LDGs contrast strongly with the generally unimodal gradients of today, potentially reflecting high global temperatures and prevailing Pangaean super-monsoonal climate system during the Permo-Triassic.