Miracle-dz/UniFAR-FTUs huggingface dataset:
Preimplantation Genetic Diagnosis

INSTRUCTIONS FOR USE Coverage Positions are intended to supplement certain standard CIGNA HealthCare benefit plans. Please note, the terms of a participant’s particular benefit plan document [Group Service Agreement (GSA), Evidence of Coverage, Certificate of Coverage, Summary Plan Description (SPD) or similar plan document] may differ significantly from the standard benefit plans upon which these Coverage Positions are based. For example, a participant’s benefit plan document may contain a specific exclusion related to a topic addressed in a Coverage Position. In the event of a conflict, a participant’s benefit plan document always supercedes the information in the Coverage Positions. In the absence of a controlling federal or state coverage mandate, benefits are ultimately determined by the terms of the applicable benefit plan document. Coverage determinations in each specific instance require consideration of 1) the terms of the applicable group benefit plan document in effect on the date of service; 2) any applicable laws/regulations; 3) any relevant collateral source materials including Coverage Positions and; 4) the specific facts of the particular situation. Coverage Positions relate exclusively to the administration of health benefit plans. Coverage Positions are not recommendations for treatment and should never be used as treatment guidelines. ©2007 CIGNA Health Corporation
Problèmes de linéarisation dans des familles de germes analytiques.

Nous nous interessons a la linearisation de certaines familles de germes analytiques. En generalisant les definitions et proprietes du diametre transfini, nous obtenons un theoreme de majoration polynomiale valable a la fois pour les nombres complexes et p-adiques. Nous utilisons ensuite ces outils pour donner une nouvelle demonstration du theoreme de Perez-Marco concernant la linearisation des familles non resonantes de germes analytiques qui subissent une perturbation polynomiale. Cette nouvelle preuve permet de demontrer un analogue du theoreme de Perez-Marco dans le cadre p-adique. De plus, cette nouvelle technique nous permet de recuperer une information diophantienne et donne de nouveaux exemples de germes non linearisables. Nous generalisons ensuite ce theoreme au cas des perturbations par des fractions rationnelles et finissons par etudier un cas resonant et retrouvons, de facon elementaire, certaines proprietes concernant le centralisateur des germes tangents a l'identite.
WHODAS Assessment Feasibility and Mental Health Impact on Functional Disability in Systemic Lupus Erythematosus

Systemic lupus erythematosus (SLE), besides rheumatological dysfunction, manifests in neuropsychiatric disorders like depression and anxiety. Mental health illnesses in SLE patients have a high prevalence and a profound impact on quality of life, generating an increased disability and premature mortality. This study aimed to establish the degree of disability in patients with SLE and the impact of depression and anxiety on patients’ functioning. Additionally, the study aimed to verify whether World Health Organization-Disability Assessment Schedule (WHODAS) 2.0 is suitable for the evaluation of patients with SLE associating depression and/or anxiety symptoms. Cross-sectional research was performed, including adult patients, diagnosed with SLE. To evaluate depression, anxiety, and functioning, approved questionnaires Hamilton Anxiety Rating Scale, Hamilton Depression Rating Scale, and, World Health Organization-Disability Assessment Schedule (WHODAS) were applied. Confirmatory factor analysis was performed on WHODAS subscales. Sixty-two patients were included in the research, with a mean of SLE diagnosis of 12.48 years; 53 patients (85%) had depression (p < 0.001). Anxiety was found in 38 patients (61.29%, p < 0.05). WHODAS assessment results depicted that 39 patients (62.90%, p < 0.05) manifested disability, from which 26 (66.66%, p < 0.05) presented moderate and severe disability. A strong correlation between the severity of anxiety and the degree of disability (r > 0.6, p < 0.001) was found. The WHODAS scale assessment proved to be a valuable tool for SLE patient’s functioning assessment. This study suggests that depression and anxiety negatively impact WHODAS disability scores, decreasing the quality of life in SLE patients.
Determination of Nutritional Value of Alfalfa Varieties and Lines by Using the In Vitro Method and Gas Production Technique

This study was organized to determine the nutritional value of different alfalfa varieties and lines selected within the scope of the “Cukurova Region Alfalfa Breeding Project”, conducted at the Eastern Mediterranean Agricultural Research Institute, by using the in vitro gas production technique. In the project, Nimet was certified as a new variety. The used alfalfa lines were YSH 26-12, YSH 23-9, YSH 21-1, YSH 27-9, YSH 37-12, YSH 35-11, YSH 28-6, YSH 16-11, YSH 14-3, and YSH 11-4. The certified Nimet variety was used as a control. Alfalfas have been harvested in April, at the beginning of blooming. Chemical composition, metabolic energy (ME), net energy lactation (NEL), and organic matter digestibility (OMD) of the certified Nimet variety with 10 different alfalfa lines used in the experiment were determined by Hohenheim in vitro gas production technique. The incubation times in the Hohenheim gas production technique are 3, 6, 9, 12, 24, 48, 72 and 96th hours. Crude protein (CP), crude cellulose (CC), NDF, and ADF contents of the alfalfa varieties and lines ranged between 19.06-22.40%, 24.90-33.30%, 33.16-45.73%, and 30.77-39.75%, respectively. After 96-hour incubation, the highest total gas production (GP) was found at the YSH 11-4 line (45.32 ml) (P < 0.05). While ME, OMD and NEL contents were found to be high at the YSH 11-4 line, ME and OMD values were statistically different from the YSH 28-6, YSH 16-11, YSH 14-3, and YSH 21-1 lines. On the other hand, NEL values were determined different from YSH 23-9, YSH 21-1, YSH 28-6, YSH 16-11, YSH 14-3 lines.
Gradual Introduction of CAAD to Develop and Support Students’ Ability in Design Studio

How to integrate CAAD into design education, and how to teach CAAD as a tool of design thinking has been a difficult issue left unresolved for architecture schools. This paper discusses the possible approach to these issues which were experienced in a Japanese university. In the first section, it will summarize the present situation of CAAD education in Japan. The second section reports the framework of design education and roles of CAAD programmed in a department. The third section introduces an example of course programs and students’ work. The fourth section observes a recent outcome of experimented program, such as, students’ work, scores and some results of a student questionnaire. In the final section, it will discuss the approach that introduce different levels of CAAD usage to design studios as the level of design education advances, was successful to integrate CAAD into design education.
Bandung as an International Relations Actor Through the Collaboration of Bandung and Fort Worth Sister City in International Leadership Academy Program

Pemerintah Kota merupakan salah satu subjek yang mulai berkiprah di dunia internasional. Di sisi lain, kota dipandang sebagai lembaga dalam 'global governance' yang bekerja sama untuk memecahkan masalah global secara global. Penelitian ini bertujuan untuk menjelaskan kota Bandung dalam menampilkan dirinya sebagai subjek hubungan internasional melalui implementasi kerjasama sister city antara kota Bandung dan kota Forth Worth dalam program International Leadership Academy (ILA). Metode penelitian yang digunakan adalah penelitian kualitatif dengan pengumpulan data melalui wawancara dan studi pustaka. Sedangkan kerangka konseptual yang digunakan terdiri dari konsep kerjasama internasional dan konsep sister city. Sejak tahun 2010 hingga tahun 2021 delegasi kota Bandung yaitu siswa SMA didampingi oleh pengawas dan karyawan mengikuti program ILA yang diadakan setiap tahun di Kota Fort Worth. Kehadiran delegasi ini mewakili Kota Bandung sebagai subjek hubungan internasional. Melalui kegiatan ILA di kota Fort Worth dengan siswa SMA Bandung sebagai delegasinya, kota Bandung dijamin kehadirannya di kancah internasional hampir setiap tahun. Namun sayangnya, Pemerintah Kota Bandung tidak sepenuhnya mendukung kegiatan program pertukaran pemuda ILA yang diadakan di kota Fort Worth. Padahal dukungan ini penting untuk menjaga kelangsungan keberadaan Kota Bandung sebagai subjek dalam hubungan internasional.
Information Redundancy as an Information Theoretic Criterion for Onset Detection

We propose a criterion, called ‘maximal redundancy’, for onset detection in time series. The concept redundancy is inspired from information theory and indicates how well a signal locally can be explained by an underlying model exploiting past observations. It is shown that a local maximum in the redundancy is a good indicator for an onset. It is proven that ‘maximal redundancy’ detection is a statistical asymptotically optimal detector for AR processes. Moreover, the detector accounts for nonGaussianity of the innovations in the AR processes, using negentropy. Several applications are shown where the new criterion has been successfully applied.
Analysing climatic variability and extremes events in the Himalayan regions focusing on mountainous urban agglomerations

Abstract The present study highlights the long-term variations in temperature and precipitation using time series datasets of CRU and ERA5-Land across the Himalayan region. The Mann-Kendall and Sen’s slope-based trend analysis exhibited an apparent warming trend in the region, with higher increase in Tmin (1.5 °C) and comparatively lower increase in Tmax (0.8 °C) during 1901–2018. The joint CCl/WCRP/JCOMM based 19 extreme indices elucidated an increasing frequency of warm days (16%) in Central Himalayan urban agglomerations (HUAs) with a declining number of cold days (−6%) and cold nights (−4%) during 2000–2019. The moderate decline in the wet days (8%) and consecutive wet days (−5 days/20 years) observed in all HUAs compared to an increasing frequency of the consecutive dry days (3 days/20 years). Study reported higher warming in Kathmandu UA, while increased precipitation in Srinagar UA, and contributes to framing climate change adaptation and mitigation strategies in the mountainous system.
Negative attitudes and perceptions of black South African accents in higher education institutions of the Western Cape Province

There is a negative approach and perception of the black South African accent in Drama Departments of higher education institutions in South Africa. The purpose was to discover the experiences of being an actor-in-training at a Drama Department at the University of Cape Town (UCT) and The South African School of Motion Picture Medium and Live Performance (AFDA). The research method was a qualitative design, and the sampling method was purposive. The inclusion criteria considered participants who could speak at least one South African language other than English. In other words, the researcher selected black South African natives from the Nguni language groups (isiZulu, isiXhosa, Siswati, isiNdebele) and Bantu language groups (Sesotho, Northern Sotho or Sepedi, Setswana). The exclusion criteria considered anyone registered at UCT or AFDA or already graduated with a degree certificate from those institutions. The researcher analysed the data using the Tesch analysis method. The study has communicated the effects of a voice-training syllabus that ignores authentic black South African vocal abilities. The participants’ experiences have shown a lack of interest in honing and encouraging black South African accents in the voice-training syllabus at Drama Departments in South African universities. It was concluded that there is more emphasis and attention given to British and American accents in the voice-training syllabus in South African universities and that black actors-in-training are encouraged to perform in these accents. The participants expressed that they do not feel prepared to perform characters with black South African accents because of this training.
Explore AI and machine learning for future ISR collection planning and management

The current airborne ISR (Intelligence, Surveillance, and Reconnaissance) collection planning and management is designed for the employment of a limited number of large ISR platforms with respect to a set of collection requirements created through an assembly line-like process. This process is often very cumbersome and mentally exhaustive for intelligence analysts when dealing with a large volume of dynamic all-source intelligence. Consequently, more human time and resources are spent on processing and digesting raw data, instead of strategizing and designing the most effective ISR collection plans. These problems could be amplified significantly in potential future conflicts with a near-peer adversary because the complexity, scale, and intensity of an airborne ISR operation could be several orders higher. This paper discusses our new research concepts and preliminary results in applying artificial intelligence (AI) and machine learning (ML) as proof-of-concepts for facilitating future ISR collection planning and management. We explored a dynamic knowledge graph to represent historical and current all-source intelligence data as well as the corresponding contextual relationships and temporal states. Such an accumulative knowledge base allows us to apply machine learning and other analytical methods to infer and visualize multi-layered intelligence on an adversary’s capabilities and operations. These analytical results could assist human ISR analysts in understanding adversary’s operational tactics, techniques, and procedures. We further look into AI-enabled virtual agents in assisting mission planners to best manage a group of ISR assets for fulfillment of collection requirements. Applying deep reinforcement learning to Intellection, a new cooperative multi-player ISR collection board game, we train the virtual agents into AI players who can follow the game rules and estimate the desirable flight paths for potentially maximizing successful collections over prioritized targets. Together, these explorations may potentially create decision advantages and relieve possible manpower bottlenecks in future fastpaced ISR collection planning and management.
Rich cities, poor countryside? Social structure of the poor and poverty risks in urban and rural places in an affluent country

This paper contributes to the field of regional poverty literature by using linked tax data to examine poverty in a large district in Switzerland with one million inhabitants and rural and urban parts. We measure poverty using income and asset-based approaches. Our regional comparison of the social structure of the poor shows that poor people in rural areas are more likely to be of retirement age. Among the workforce, the share of poor is larger for those who work in agriculture compared to those working in industry or the service sector. In urban areas, the poor are more often freelancers and people of foreign origin. Despite where they live, people with little education, single parents, and people working in gastronomy/tourism are disproportionately often poor. We then use a random forest based variable importance assessment to clarify whether the importance of poverty risks factors differs in urban and rural locations. It shows little regional differences among the major poverty risk factors, and it demonstrates that the opportunity structure, like density of workplaces or aggravated access in mountain areas, seem to be of minor importance compared to risk factors that relate to the immediate social situation.
Novel Higgs decays and dark matter in the exceptional supersymmetric standard model

The Exceptional Supersymmetric (SUSY) Standard Model (E{sub 6}SSM) predicts three families of Higgs doublets plus three Higgs singlets, where one family develops vacuum expectation values (VEVs), while the remaining two which do not are called Inert. The model can account for the dark matter relic abundance if the two lightest Inert neutralinos, identified as the (next-to) lightest SUSY particles ((N)LSPs), have masses close to half the Z mass. In this case we find that the usual SM-like Higgs boson decays more than 95% of the time into either LSPs or NLSPs. The latter case produces a final state containing two leptons l{sup +}l{sup -} with an invariant mass less than or about 10 GeV. We illustrate this scenario with a set of benchmark points satisfying phenomenological constraints and the WMAP dark matter relic abundance. This scenario also predicts other light Inert chargino and neutralino states below 200 GeV, and large LSP direct detection cross sections close to current limits and observable soon at XENON100.
Contextual anomaly detection for high-dimensional data using Dirichlet process variational autoencoder

Abstract Due to recent advances in sensing technologies, response measurements of various sensors are frequently used for system monitoring purposes. However, response data are often affected by some contextual variables, such as equipment settings and time, resulting in different patterns, even when the system is in the normal state. In this case, anomaly detection methods that do not consider contextual variables may be unable to distinguish between abnormal and normal patterns of the response data affected by the contextual variables. Motivated by this problem, we propose a method for contextual anomaly detection, particularly in the case where the response and contextual variables are both high-dimensional and complex. The proposed method is based on Variational AutoEncoders (VAEs), which are neural-network-based generative models suitable for modeling high-dimensional and complex data. The proposed method combines two VAEs: one for response variables and the other for contextual variables. Specifically, in the latent space of the VAE for contextual variables, we model the latent variables using a Dirichlet process Gaussian mixture model. Consequently, the effects of the contextual variables can be modeled using several clusters, each representing a different contextual environment. The latent contextual variables are then used as additional inputs to the other VAE’s decoder for reconstructing response data from their latent representations. We then detect the anomalies based on the negative reconstruction loss of a new response observation. The effectiveness of the proposed method is demonstrated using several benchmark datasets and a case study based on a global tire company.
Sexual violence and mental health among young bi+ and lesbian women and gender minoritized people

Abstract Introduction Sexual minoritized people report worse mental health and are at risk of sexual violence compared to their heterosexual peers. Method We conducted a survey to explore sexual stigma, sexual violence, and mental health among 326 bi+ and lesbian women and gender minoritized people age 18–25. Results Mental health did not differ by sexual identity; sexual stigma and violence were associated with negative mental health symptoms, as were identifying as BIPOC, as trans or nonbinary, or having less formal education. Conclusion Sexual stigma and violence are related to mental health among young bi+ and lesbian women and gender minoritized people.
Risk Factors and In-hospital Outcome of Young Adults Presented with Acute Myocardial Infarction and Treated with Primary PCI

Background: Acute myocardial infarction (AMI) is often characterised pathologically as the death of cardiomyocytes as a consequence of persistent ischaemia result in an acute imbalance among oxygen supply and demand. Coronary artery disease (CAD) is the leading cause of death worldwide. AMI mainly affects patients older than 40 years of age, however, young can suffer MI. In the developing countries, CAD is becoming an epidemic, where it occurs in younger persons at greater rates. Clinical features and prognosis of young patients tend to vary from those of older individuals. the outcomes of a MI may be especially severe at a young age because of its larger potential influence on the patient's psyche, capacity to work, and socioeconomic burden. AMI is less prevalent in young people than in older persons, since only 2 to 6 % of the younger population suffers from the condition. Primary PCI is the optimal therapy for STEMI if it can be done promptly, preferably within 90-120 minutes of provider contact. Methods: The present research performed on 60 subjects who had AMI and treated with primary PCI. The cases were allocated into 2 groups, group 1 involved young subjects aged 40 years old or less (30 patients) and group 2 involved older patients aged more than 40 years (30 patients). All patients underwent complete history taking, cardiological clinical examination, investigations, coronary angiography and PCI. Results: Concerning age there was statistically significant difference among two groups while there was no significant difference regarding to sex. regarding risk factors there was significant difference among both groups regarding to hypertension, DM, previous MI, cerebrovascular disease and drug abuse. Regarding to laboratory investigation, there was no significant difference regarding CK, CKMB, creatinine and random blood sugar. There was no significant difference regarding to culprit artery and TIMI flow after PCI while there was statistically significant difference regarding number of vessels involved. Regarding to outcome there was no significant variation among the two groups regarding to acute HF, cardiogenic shock, re-infarction, and death. As regarding to bleeding, it was significant higher in group II. Conclusions: Prevalence of Acute ST Elevation Myocardial Infarction “STEMI” in young people is increasing due to sedentary and stressful lifestyle and bad habits as smoking and addiction. The most widespread and important risk factors in these patients are smoking, addiction, mental stress and hyperlipidemia with less prevalence of hypertension and diabetes mellitus. Young patients present most commonly with anterior then inferior STEMI.
Cumulative Stress of Single Mothers - An Exploration of Potential Risk Factors

Studies report that single mothers are at a higher risk for psychological stress than married mothers. This study investigates which risk factors are relevant for the stress of single mothers and how much the maternal stress depends on the number of stressors occurring in combination. For this purpose, multiple regression analyses as well as ANOVAs were calculated using data from 923 single mothers from Germany. Factors influencing single mothers' stress are (1) low parenting self-efficacy beliefs on the part of the mother, (2) at least one child with a disability, (3) low perceived social support, (4) a new partnership, and (5) the age of the youngest child. Cumulation of several stressors causes a significant increase in stress in the domain resulting from the child's behavior and characteristics, i.e. single mothers with several simultaneously occurring stressors experience many times more stress especially in this domain than those who are affected by only one stressor. Our findings suggest that it is not sufficient to focus interventions on the relative disadvantages of single mothers, but that the combined occurrence of different stressors and their cumulative effect should be focused on in prevention and intervention.