Miracle-dz/UniFAR-FTUs huggingface dataset:
Assessment of Diversity of Culturable Marine Yeasts Associated with Corals and Zoanthids in the Gulf of Thailand, South China Sea

Marine yeasts can occur in a wide range of habitats, including in marine invertebrates, in which they may play important roles; however, investigation of marine yeasts in marine invertebrates is scarce. Therefore, this study aims to explore the diversity of yeasts associated with corals and zoanthids in the Gulf of Thailand. Thirty-three coral and seven zoanthid samples were collected at two sampling sites near Mu and Khram islands. Fifty yeast strains were able to be isolated from 25 of the 40 samples collected. Identification based on sequence analyses of the D1/D2 domain of the large subunit rRNA gene revealed a higher number of strains in the phylum Basidiomycota (68%) than in the phylum Ascomycota. The ascomycetous yeasts comprised nine known species from four genera (Candida, Meyerozyma, Kodamaea, and Wickerhamomyces), whereas the basidiomycetous yeasts comprised 10 known species from eight genera (Vishniacozyma, Filobasidium, Naganishia, Papiliotrema, Sterigmatomyces, Cystobasidium, Rhodotorula, and Rhodosporidiobolus) and one potentially new species. The species with the highest occurrence was Rhodotorula mucilaginosa. Using principal coordinate analysis (PCoA) ordination, no marked differences were found in the yeast communities from the two sampling sites. The estimation of the expected richness of species was higher than the actual richness of species observed.
Investigating physical activity knowledge and beliefs as correlates of behaviour in the general population: a cross-sectional study

ABSTRACT This study examines knowledge of physical activity (PA) guidelines for cancer prevention and beliefs of the role of PA in preventing cancer as correlates of moderate-to-vigorous intensity PA (MVPA) behaviour among adults. Measures assessing socio-demographic characteristics, knowledge of PA guidelines, and PA beliefs and behaviour were completed online by 654 adults (Mage = 36.92 ± 14.61 years) with no history of cancer. Data were analyzed descriptively and using unadjusted and adjusted logistic regression analysis. Approximately half the sample was aware of PA guidelines for cancer prevention (49.24%) and believed that PA was extremely effective in reducing the risk of developing cancer (48.93%). Knowledge of PA guidelines for cancer prevention was associated with a greater likelihood of being active (unadjusted odds ratio [OR]: 1.66, 95% confidence interval [95% CI]: 1.18–2.34; p <.01; adjusted OR: 2.05, 95% CI: 1.36–3.11; p <.001). Beliefs regarding the effectiveness of PA in preventing cancer was not associated with a greater likelihood of being active. There is a lack of awareness of current PA guidelines for cancer prevention. Experimental studies are needed to further explore if increasing adults’ knowledge of PA guidelines for cancer prevention can enhance PA levels.
Melting and Recrystallization of Copper Nanoparticles Prepared by Microwave-Assisted Reduction in the Presence of Triethylenetetramine

The small sized copper nanoparticles (Cu-NPs), prepared in the presence of triethylene tetramine (TETA) and assisted with microwave irradiation, have an extremely low melting temperature. Melting of the small sizezd Cu-NPs can be triggered by the heat generated from the e-beam irradiation during SEM and TEM image construction. The dispersed Cu atoms around the agglomerated big Cu particles can undergo recrystallization immediately due to the strong driving force of the huge temperature difference to normal melting temperature (Tm = 1085 °C). Some of the Cu-NPs with bigger sizes also recrystallize and agglomerate into dense, big particles. According to X-ray diffraction patterns, these particles can agglomerate into compact, ordered Cu crystals in less than five minutes at 60 °C. The melting and recrystallization related endothermic and exothermic phase transitions of Cu-NPs can be found from differential scanning calorimeter (DSC) thermograms and optical microscopic pictures.
A Study on the Method to Predict Peripheral Arterial Disease (PAD) by using Finger-Toe Index (FTI)

In this paper, the purpose is to propose a new and a simpler parameter than the previous method which uses an ordinary blood pressure cuff and a Doppler ultrasound blood flow detector in order to predict the severity of PAD(Peripheral arterial disease). For the simpler system, we developed 4 channels of PPG (photoplethysmography) and proposed a new analysis parameter: finger-toe index (FTI). In order to verify the usefulness of the developed system and the new analysis parameter, the experiments were performed on 43 normal subjects. The new analysis parameter: FTI was compared with ABI (ankle-brachial index) using regression analysis method. There are two main findings of this study: first, the proposed parameter, FTI is more strongly correlated with age than ABI. The correlation coefficient between each parameter, FTI & ABI, and age was observed to be 0.642 and 0.271 respectively. The regression coefficient between the parameters, FTI & PTT, and ABI & PTT was observed to be 0.60 and 0.10 respectively. Secondly, the proposed parameter is a more quantitative index. For the same subject group (n=43), the result of ABI showed that all subjects are in a single state group but the results of FTI classified the subjects into three state group.
Practical guidance for using the FreeStyle Libre flash continuous glucose monitoring in primary care

ABSTRACT Use of continuous glucose monitoring (CGM) improves clinical outcomes in type 1 diabetes, and significant benefits been demonstrated in patients with type 2 diabetes, including improved glycemic control, better treatment adherence, and an increased understanding of their treatment regimens. Currently, there are two types of CGM systems: real-time CGM (rtCGM) and flash CGM (FCGM). Retrospective analysis of CGM data allows patients and their clinicians to identify glycemic patterns that support and facilitate informed therapy decisions. With the increasing prevalence of diabetes, primary care physicians will be compelled to take on more responsibility for managing patients with diabetes. This article focuses on practical approaches and decision-making strategies for utilizing FCGM in primary care settings.
Primary Cutaneous CD4+ Small/Medium T-cell Lymphoproliferative Disease: A Case Report

Primary cutaneous lymphoma is a heterogeneous group of diseases. Primary cutaneous CD4+ small/medium Tcell lymphoma (CD4+ SMTCL) is one of the rare subtypes; representing only 2-3% of all cutaneous lymphomas. It was recently described as lymphoproliferative disorder because of its indolent clinical behavior and many similarities with cutaneous pseudolymphoma. This disease is a provisional entity according to latest World Health Organization (WHO) classification of hematolymphoid tumors. CD4+ SMTCL has a n excellent 5-year survival of 60-85%. CD4+ SMTCL usually present with a solitary skin lesion of the head and neck region, and most of reported cases were treated with local managements only. The common clinical presentations and histological features are still not well understood, and no optimal therapy is established. We report a case of primary cutaneous CD4+ small/medium Tcell lymphoma, our patient presented with a facial skin lesion that was treated with excision only.
Ciliary IFT80 is essential for intervertebral disc development and maintenance

The intervertebral disc degeneration (IVDD)‐related diseases occur in more than 90% of the population older than 50 years. Owing to the lack of understanding of the cellular mechanisms involved in IVDD formation effective treatment options are still unavailable. Primary cilia are microtubule‐based organelles that play important roles in the organ development. Intraflagellar transport (IFT) proteins are essential for the assembly and bidirectional transport within the cilium. Role of cilia and IFT80 protein in intervertebral disc (IVD) development, maintenance, and degeneration are largely unknown. Using cilia‐GFP mice, we found presence of cilia on growth plate (GP), cartilage endplate (EP) annulus fibrosus (AF), and nucleus pulposus (NP) with varying ciliary length. Cilia length in NP and AF during IVDD were significantly decreased. However, cilia numbers increased by 63% in AF during repair. Deletion of IFT80 in type II collagen‐positive cells resulted in cilia loss in GP and EP, and disrupted IVD structure with disorganized and decreased GP, EP, and internal AF (IAF), and less compact and markedly decreased gel‐like matrix in the NP. Deletion of IFT80 in type I collagen‐positive cells led to a disorganized outer AF (OAF) with thinner, loosened, and disconnected fiber alignment. Mechanistic analyses showed that loss of IFT80 caused a significant increase in cell apoptosis in the IVD, and a marked decrease in expression of chondrogenic markers ‐ type II collagen, sox9, aggrecan, and hedgehog (Hh) signaling components, including Gli1 and Patch1 in the IVD of IFT80fl/fl; Col2‐creERT mice, and Gli1 and Patch1 expression in the OAF of IFT80fl/fl; Col1‐creERT mice. Interestingly, Smoothened agonist‐SAG rescued OAF cell proliferation and osteogenic differentiation. Our findings demonstrate that ciliary IFT80 is important for the maintenance of IVD cell organization and function through regulating the cell survival and Hh signaling.
Left ventricular remodelling in chronic primary mitral regurgitation: implications for medical therapy

Summary Surgical repair or replacement of the mitral valve is currently the only recommended therapy for severe primary mitral regurgitation. The chronic elevation of wall stress caused by the resulting volume overload leads to structural remodelling of the muscular, vascular and extracellular matrix components of the myocardium. These changes are initially compensatory but in the long term have detrimental effects, which ultimately result in heart failure. Understanding the changes that occur in the myocardium due to volume overload at the molecular and cellular level may lead to medical interventions, which potentially could delay or prevent the adverse left ventricular remodelling associated with primary mitral regurgitation. The pathophysiological changes involved in left ventricular remodelling in response to chronic primary mitral regurgitation and the evidence for potential medical therapy, in particular beta–adrenergic blockers, are the focus of this review.
Conjoint Analysis Tools for Developing Country Contexts

Conjoint analysis has long been used in marketing research, but has recently become popular in political science. Originally developed by Luce and Tukey in 1964, conjoint analysis serves as a useful tool for understanding preferences over multidimensional alternatives. This method presents respondents with profiles — for example of candidates (Carlson, 2015; Rosenzweig and Tsai, N.d.) or immigrants (Hainmueller and Hopkins, 2014; Berinsky et al., 2015) — that have randomly assigned attributes and asks respondents to evaluate and choose between them. The random assignment of profile characteristics allows researchers to identify the causal influence of attributes on a person’s decision to vote for a candidate or allow an immigrant into the country. [1]
THE ANALYSIS OF HYSTERESIS IN LOW CYCLE FATIGUE OF STEEL DAMPERS FOR EARTHQUAKE APPLICATION ANALIZA

Each civil engineering structure inevitably passes the phase of low cycle fatigue during strong impact loads of the earthquake, and light structures often fail due to loss of local or global stability (local buckling or deflection of structural components. It is practically impossible to understand the behaviour of buildings subjected to seismic loads without base knowledge of behaviour of structural components during lowcycle fatigue process as well as the global stability of the structures during all phases of earthquake action. Low cycle fatigue is examined theoretically and experimentally, using damage mechanics concept. Special attention is paid to ultra low cycle fatigue, in the sense DufaillyLemaitre. The theory is applied on dampers for strengthening structures damaged in the earthquake. Theoretical considerations are also experimentally checked. Ključne reči • histerezis • oštećenje • prigušivač • integritet konstrukcije
KONA Powder and Particle Journal No. 37 (2020) 132–144/Doi:10.14356/kona.2020017

The discrete element method (DEM) and the moving particle semi-implicit (MPS) method are the most popular mesh-free particle methods in the discontinuum and continuum. This paper describes a state-of-the-art modeling on multi-phase flows using these mesh-free particle methods. Herein, a combinational model of the signed distance function (SDF) and immersed boundary method (IBM) is introduced for an arbitrary-shaped wall boundary in the DEM simulation. Practically, this model uses a simple operation to create the wall boundary. Although the SDF is a scalar field for the wall boundary of the DEM, it is useful for the wall boundary of the CFD through combination with the IBM. Validation tests are carried out to demonstrate the adequacy of the SDF/IBM wall boundary model. Regarding the mesh-free particle method for continuum, the phase change problem is one of the challenging topics, as the solid state is usually modeled by extremely high viscous fluid in the phase change simulation. The phase change simulation is shown to be efficiently performed through an implicit algorithm and a heat flux model in the MPS method. The adequacy of these models is verified by the numerical examples.
IN VITRO CALLUS INDUCTION AND SHOOT REGENERATION OF DECALEPIS ARAYALPATHRA (JOSEPH AND CHANDRAS) VENTER

The aim of the present study was to develop an efficient protocol for callus induction, shoot regeneration, biomass and antioxidant activity of Decalepis arayalpathra. The different explants were cultured on MS medium supplemented with different concentration of auxins and cytokinins. The total phenolic content and antioxidant activities were determined by standard procedures. Callus induction was higher from leaf explants on media supplemented with individual growth regulator (2 mg/L of 2, 4-D, and 1 mg/L of BAP). However, combination of BAP (2 mg/L) + 2, 4-D (1 mg/L) and BAP (1 mg/L) + NAA (0.5 mg/L) resulted in maximum callus induction. The callus biomass was significantly higher in medium supplemented with BAP (2 mg/L) + NAA (1 mg/L). Shoot regeneration was higher from shoot tip and nodal explants on medium fortified with BAP (1.0 mg/L) + NAA (0.2 mg/L) & IBA (0.5 mg/L). Root induction was maximum on half strength MS medium supplemented with IBA (0.5 mg/L) and NAA (0.2 mg/L). The plants were subjected to hardening and showed around 70% of survival after acclimatization. The total phenolic content and antioxidant activities were significantly higher in methanolic extract of leaf compared to callus. Our results demonstrated that leaf and nodal explants are the good source for the callus induction and shoot regeneration, which might be helpful in mass propagation and conservation of this medicinally important plant.
Designing Anonymity Server based on K Optimal Principle for Privacy Preserving Protocol

 Abstract —There is need to secure mobile phones locations by privacy frame work which utilizes K optimal principles. This improves the location position and tracking ability of Cell phones. Most of the time quality of service cannot be provided because K no. of users may not be available at the time of request. This motivates to create dummy requests at real time, to assure K principle. Another motivation is to split additional load that occurs on Location Based Services (LBS) for adding Anonymization Server (AS) in between Mobile Station (MS) and LBS. To find out nearby location like banks, hotels etc. An algorithm that process mobile request using K secrecy with variety of considerations and different parameters like real world traffic volume data and dummy mobile users generated practically by mobile objects generator to achieve K optimal principle. By this temporal clocking problem solved as there is no waiting request.
Masking the detection of taste stimuli in rats: NaCl and sucrose.

While psychophysical and neurophysiological assessments of taste sensitivity to single chemical compounds have revealed some fundamental properties of gustatory processing, taste stimuli are rarely ingested in isolation. Arguably, the gustatory system was adapted to identify and report the presence of numerous chemicals ingested concurrently. To begin systematically exploring the detectability of a target stimulus in a background in rodents, we used a gustometer to trained rats in a two-response operant task to detect either NaCl (n=8) or sucrose (n=8) dissolved in water, and then tested the sensitivity of rats to the trained NaCl stimulus dissolved in a sucrose masker (0.3, 0.6, or 1.0 M, tested consecutively) vs. sucrose, or the trained sucrose stimulus dissolved in a NaCl masker (0.04, 0.2, or 0.4 M) vs. NaCl. Detection thresholds (EC50 values) were determined for the target stimulus dissolved in each concentration of the masker. Except for 0.04 M NaCl, all masker concentrations tested increased the target stimulus EC50. Target stimulus detectability decreased systematically as masker concentrations increased. The shift in liminal sensitivity for either target was similar when the threshold for the masker was considered. At least for these prototypical stimuli, it appears that the attenuating impact of a masker on the detection of a target stimulus depends on sensitivity to the masking stimulus. Further study will be required to generalize these results and extend them to more complex maskers, and to discern neural circuits involved in the detection of specific taste signals in the context of noisy backgrounds.
Ghost Introgression: Spooky Gene Flow in the Distant Past

Evolution is a continuous trial and error process in which most lineages go extinct without leaving fossil remains. Many of these lineages would be closely related and occasionally hybridized with lineages that gave rise to extant species. Hence, it is likely that one can find genetic signatures of these ancient introgression events in present‐day genomes, so‐called ghost introgression. The increasing availability of high‐quality genome assemblies for non‐model organisms and the development of more sophisticated methods for detecting introgression will undoubtedly reveal more cases of ghost introgression, indicating that the Tree of Life is even more reticulated than assumed. The presence of ghost introgression has important consequences for the study of numerous evolutionary processes, including adaptation, speciation, and macroevolutionary patterns. In addition, detailed studies of introgressed regions could provide insights into the morphology of the extinct lineage, providing an unexpected link between genomics and the fossil record. Hence, new methods that take into account ghost introgression will need to be developed.
Handgrip strength is inversely associated with fatal cardiovascular and all-cause mortality events

Abstract Purpose: We aimed to assess the associations of handgrip strength (HS) with cardiovascular and all-cause mortality and whether adding data on HS to cardiovascular disease (CVD) risk factors is associated with improvement in CVD mortality prediction. Design: Handgrip strength was assessed in a population-based sample of 861 participants aged 61–74 years at baseline. Relative HS was obtained by dividing the absolute value by body weight. Results: During a median (interquartile range) follow-up of 17.3 (12.6–18.4) years, 116 fatal coronary heart diseases (CHDs), 195 fatal CVDs and 412 all-cause mortality events occurred. On adjustment for several risk factors, the hazard ratios (95% confidence intervals (CIs)) for fatal CHD, fatal CVD and all-cause mortality were 0.59 (0.37–0.95), 0.59 (0.41–0.86) and 0.66 (0.51–0.84), respectively, comparing extreme tertiles of relative HS. Adding relative HS to a CVD mortality risk prediction model containing established risk factors did not improve discrimination or reclassification using Harrell’s C-index (C-index change: 0.0034; p = .65), integrated-discrimination–improvement (0.0059; p = .20) and net-reclassification-improvement (–1.31%; p = .74); however, there was a significant difference in –2 log likelihood (p < .001). Conclusions: Relative HS is inversely associated with CHD, CVD and all-cause mortality events. Adding relative HS to conventional risk factors improves CVD risk assessment using sensitive measures of discrimination. KEY MESSAGES Handgrip strength (HS) assessment is simple, inexpensive and it takes only a few minutes to measure in clinical practice; however, its prognostic role for fatal cardiovascular outcomes on top of traditional risk factors in apparently healthy populations is uncertain. In a population-based prospective cohort study, good HS adjusted for body weight was associated with lower risk of fatal cardiovascular outcomes and the associations remained consistent across several clinically relevant subgroups. Handgrip strength may be a useful prognostic tool for fatal CHD and CVD events, in the general population.
Changes in perceptions of ethical leadership: Effects on associative and dissociative outcomes.

From employees' point of view, changes in ethical leadership perceptions can signal important changes in the nature of the employment relationship. Guided by social exchange theory, this study proposes that changes in ethical leadership perceptions shape how employees appraise their exchange relationship with the organization and affect their pride in or contempt for the organization. Changes in these associative/dissociative emotions, in turn, precipitate changes in behaviors that serve or hurt the organization, notably voice and turnover. Experimental data collected from 900 subjects (Study 1) and field data collected from 470 employees across 4 waves over 14 months (Study 2) converged to show that changes in ethical leadership perceptions were related to same-direction changes in employees' pride in the organization and to opposite-direction changes in their contempt for the organization above and beyond the effect of the present ethical leadership level. Changes in pride were in turn related to same-direction changes in functional voice, whereas changes in contempt were related to same-direction changes in dysfunctional voice. The field study also provided evidence that when pride increased (decreased), employees were less (more) likely to leave the organization 6 months after. These results suggest that changes in ethical leadership perceptions are meaningful on their own, that they may alter employees' organization-targeted behaviors, and that changes in associative/dissociative emotions are the mediating mechanism. (PsycInfo Database Record (c) 2020 APA, all rights reserved).