Miracle-dz/UniFAR-FTUs huggingface dataset:
Compact Ammonia/Water Absorption Chiller of Different Cycle Configurations: Parametric Analysis Based on Heat Transfer Performance

Ammonia/water absorption chillers are driven by low-grade heat and cover wide refrigeration temperatures. This paper analyses single-stage ammonia/water absorption chillers. A numerical model was developed based on the heat exchanger performance. The model captures variational heat exchanger performances and describes the actual cycle with varying boundary conditions. The detrimental effects of refrigerant impurity were analysed quantitatively under different operating conditions. The model was validated with experimental data. A basic cycle and three advanced cycles were analysed for sub-zero refrigeration by comparing the thermodynamic performances. A compression-assisted cycle extended the activation temperature from 80 to 60 °C. At the heat source of 120 °C, when a counter-current desorber or bypassed rich solution was used, the COP increased from 0.51 to 0.58 or 0.57, respectively. The operating parameters included the heat source temperatures, heat sink temperatures, the mass flow rates and mass concentrations of rich solutions. Higher heat source temperatures increase cooling capacity. The increase was around 20 kW for the basic cycle of sub-zero refrigeration. There is an optimum heat source temperature maximising the COP. Higher heat source temperatures increased the refrigerant mass flow rate and reduced the mass concentration. The mass concentration can decrease from 0.999 to 0.960.
Effect of Calcium Ion Supplementation on Oral Microbial Composition and Biofilm Formation In Vitro

The oral cavity contains a variety of ecological niches with very different environmental conditions that shape biofilm structure and composition. The space between the periodontal tissue and the tooth surface supports a unique anaerobic microenvironment that is bathed in the nutrient-rich gingival crevicular fluid (GCF). During the development of periodontitis, this environment changes and clinical findings reported a sustained level of calcium ion concentration in the GCF collected from the periodontal pockets of periodontitis patients. Here, we report the effect of calcium ion supplementation on human oral microbial biofilm formation and community composition employing an established SHI medium-based in vitro model system. Saliva-derived human microbial biofilms cultured in calcium-supplemented SHI medium (SHICa) exhibited a significant dose-dependent increase in biomass and metabolic activity. The effect of SHICa medium on the microbial community composition was evaluated by 16S rRNA gene sequencing using saliva-derived microbial biofilms from healthy donors and periodontitis subjects. In this study, intracellular microbial genomic DNA (iDNA) and extracellular DNA (eDNA) were analyzed separately at the genus level. Calcium supplementation of SHI medium had a differential impact on iDNA and eDNA in the biofilms derived from healthy individuals compared to those from periodontitis subjects. In particular, the genus-level composition of the eDNA portion was distinct between the different biofilms. This study demonstrated the effect of calcium in a unique microenvironment on oral microbial complex supporting the dynamic transformation and biofilm formation.
Experimental and Computational Evaluation of Syringic Acid – Structural, Spectroscopic, Biological Activity and Docking Simulation

Abstract The single crystal of syringic acid was crystallized by slow evaporation technique and characterized using XRD, FTIR, FT-Raman, and UV-Vis spectroscopy. XRD confirms the crystalline structure as centrosymmetric monoclinic with C2/c space group. The functional groups identified by FTIR and FT Raman studies and by UV-Vis give the cut off wavelength as 276 nm. Quantum chemical calculations were performed using density functional theory. The computed and experimental vibrational wavenumbers were assigned and compared. Frontier molecular orbital research reveals the reactivity and kinetic stability of the molecule. The molecule’s reactive site is further confirmed by the Mulliken atomic charge distribution and molecular electrostatic potential surface analysis. The molecule’s absorption spectra were computed in the liquid phase (ethanol), by TD-DFT with the same basic set, which established a π to π* electronic transition and was comparable to the observed UV-Vis spectrum. The Hirshfeld analysis was used to determine the effectiveness of interactions between distinct atoms as well as their contribution. The O…H and H…H contributions are highest due to the intermolecular hydrogen bonding. The natural bond orbital analysis demonstrates the molecule’s bioactivity. The biological activity such as anti-bacterial, antioxidant and anti-cancer has been evaluated through disk diffusion, DDPH assay and molecular docking method. The zone of inhibition was clearly observed on gram-positive and gram-negative bacterium that showed the anti-bacterial property of syringic acid. The syringic acid prevents breast cancer, according to molecular docking research. Seven different types of breast cancer proteins based on different mechanisms were utilized to test the syringic acid molecule’s docking efficiency, and it was revealed that PR and HER-2 have the highest docking scores with −7.7Kcal/mol. In addition, to better understand the safety profile of syringic acid, physicochemical and pharmacokinetic properties were investigated.
Implicaciones cosmológicas de las anisotropías de temperatura y polarización de la RFCM y la estructura a gran escala del universo

espanolTanto la radiacion de fondo cosmico de microondas (RFCM) como los grandes cartografiados de galaxias han confirmado las principales implicaciones del modelo cosmologico estandar con una precision inedita. Sin embargo, Todavia hay algunas cuestiones en el aire que deberian estudiarse con mayor profundidad, porque podrian esconder la clave de nuevos y emocionantes descubrimientos. Junto con un deficit de potencia en los multipolos bajos, el satelite Planck ha confirmado un conjunto de anomalias estadisticas de gran escala en la distribucion de anisotropias de la RFCM que habian sido ya detectadas por WMAP, como por ejemplo un alineamiento de los multipolos de bajo orden, una region particularmente fria o una asimetria de potencia por hemisferios. Esta tesis se centra en el analisis de dos de estas anomalias estadisticas y en el problema de separacion de componentes en cosmologia. Se usa un metodo que utiliza la correlacion entre temperatura y polarizacion para caracterizar la naturaleza de la Mancha Fria, y se busca una modulacion dipolar en la distribucion de galaxias. El problema de separacion de componentes se presenta como un paso previo y crucial del analisis de las propiedades estadisticas de la RFCM, especialmente en aquellos experimentos que disenados para medir el modo B de polarizacion. En esta linea, describimos y aplicamos un ajuste de plantillas internas, que constituye una parte de la metodologia de SEVEM, uno de los procedimientos de separacion de componentes usados por la Colaboracion Planck. EnglishBoth the cosmic microwave background (CMB) observations and the large galaxy surveys have confirmed the main outlines of the standard model of cosmology with an unprecedented accuracy. However, there are still several open issues which should be explored in greater depth, because they could hide the key to new and exciting discoveries. Along with a deficit of low-multipole power, a series of large-scale statistical anomalies in the distribution of the CMB anisotropies, first detected by WMAP, have been confirmed by the Planck satellite with a high confidence level, including an alignment of the low-order multipoles, a particularly cold region, and a hemispherical power asymmetry. This dissertation is focused on the analysis of two of these statistical anomalies and the component separation problem. A methodology based on the cross-correlation between temperature and polarisation is used to characterise the nature of the Cold Spot, and a dipole modulation is sought in the galaxy distribution. The component separation problem is presented as a crucial previous step of the analysis of the CMB statistical properties, specially for those experiments which aim to detect primordial B-mode polarisation. Along this line, we describe and apply an internal template fitting procedure, which is actually part of SEVEM, one of the component separation methods used by the Planck Collaboration.
Contribution of Atmospheric Rivers to Antarctic Precipitation

Atmospheric rivers (ARs) are efficient mechanisms for transporting atmospheric moisture from low latitudes to the Antarctic Ice Sheet (AIS). While AR events occur infrequently, they can lead to extreme precipitation and surface melt events on the AIS. Here we estimate the contribution of ARs to total Antarctic precipitation, by combining precipitation from atmospheric reanalyses and a polar‐specific AR detection algorithm. We show that ARs contribute substantially to Antarctic precipitation, especially in East Antarctica at elevations below 3,000 m. ARs contribute substantially to year‐to‐year variability in Antarctic precipitation. Our results highlight that ARs are an important component for understanding present and future Antarctic mass balance trends and variability.
Validation of the Adapted German Versions of the Dementia Knowledge Assessment Tool 2, the Dementia Attitude Scale, and the Confidence in Dementia Scale for the General Population

Background: There are almost no validated tools in German that assess dementia knowledge, attitude toward dementia, and confidence in the general population. Objective: Translation and validation of the German version of the Dementia Knowledge Assessment Tool 2 (DKAT2), the Dementia Attitude Scale (DAS), and the Confidence in Dementia Scale (CODE). Methods: Instruments were translated into German and adapted for the general public. A convenience sample of 263 persons was recruited via an online platform. Validation of the tools’ psychometric properties consisted of an assessment of its reliability (internal consistency and 4-week test-retest reliability of a subgroup with n = 110), an analysis of its construct validity through principal component analysis and known-group analysis, convergent validity, and an item analysis for DKAT2-D. This study used the STROBE checklist for reporting. Results: Acceptable to excellent internal reliability was found for DAS-D (α= 0.90), DKAT2-D (α= 0.78), and CODE-D (α= 0.93). The principal component analysis confirmed the two-factor model for the DAS-D as well as the one-factor solution for CODE-D. The intra-class correlation coefficient between the first and the 4-week retest was good (CODE-D: 0.897; 0.849–0.929) to excellent (DKAT2-D: 0.918; 0.879–0.945 and DAS-D: 0.940; 0.910–0.960). Known-group analysis revealed that DAS-D, DKAT-D, and CODE-D could distinguish between individuals with or without experience with people with dementia and with or without participation in a dementia course. Conclusion: The German versions DAS-D, DKAT2-D, and CODE-D are reliable and valid tools to measure knowledge, attitude, and confidence in dementia in the German-speaking general population.
Novel ultralong and photoactive Bi2Ti4O11/TiO2 heterojunction nanofibers toward efficient textile wastewater treatment

The elimination of dyes from textile wastewater with a lower carbon footprint is highly contingent on the design of green catalysts. Here, we innovatively developed ultralong one-dimensional Bi2Ti4O11/TiO2 heterojunction nanofibers via electrospinning so as to photocatalytically degrade dyes efficiently and sustainably through the utilisation of renewable solar irradiation. The heterostructured Bi2Ti4O11/TiO2 nanofibers exhibited desirable activity in the visible light region through the slight shift of the absorption edge to a longer wavelength. The Bi2Ti4O11/TiO2 nanofibers calcined at 550 °C had a lower optical band gap (3.08 eV) than that of the pure TiO2 (3.32 eV), as evidenced by their higher photocatalytic degradation kinetics of a model dye (Acid Orange 7) (2.5 times greater than those of pure TiO2). The enhanced visible light photocatalytic performance arose from the formation of both the Bi2Ti4O11/TiO2 heterojunction and the effective separation of photogenerated holes and electrons. The employment of ultralong Bi2Ti4O11/TiO2 heterojunction nanofibers for dye removal/decolourisation under visible light is an efficient, cost effective and sustainable solution, which will provide significant insights for practical textile wastewater treatment in view of practical engineering applications.
Digital Transformation Security Challenges

ABSTRACT Digital transformation has become one of the most popular strategies for information systems (IS). Developing and implementing a digital strategy is a mandatory task for any organization that relies on information systems. In this digital age, an IS/IT strategy without security considerations could lead to serious data breaches. Despite all countermeasures, security remains a major concern in digital transformation, as digitization is misjudged and brings with it major security concerns. The digitization of manual goods, processes and services, as well as their use, leads to various security issues in different organizations. The aim of this study is to identify and analyze elements that are typical barriers to digital innovation in organizations. This study addresses common elements that impact the security of digital transformation through a literature review and a case study.
Nouvelles méthodes d'imagerie haute résolution pour l'analyse des composants nanoélectroniques

Ce travail de these a contribue au developpement de la techniques de test par faisceau laser en mode d'absorption deux photons (TPA). Cette technique a plus specifiquement ete utilisee pour la detection de defauts et l'injection de fautes dans les circuits integres.
The complete chloroplast genome of Alniaria alnifolia (Siebold and Zucc.) Rushforth, 2018

Abstract Alniaria alnifolia (Siebold and Zucc.) Rushforth, 2018 (alternative name: Sorbus alnifolia) belongs to the genus Alniaria of the family Rosaceae and is widely distributed in northern China, Korea, and Japan. It is an essential resource used in the construction, pharmaceuticals, and food industries. It is also used to treat various diseases, such as fever, hyperglycemia, rash, asthma, bronchitis, constipation, leprosy, anemia, and other skin ailments. In this study, we sequenced a sample of A. alnifolia and determined its complete chloroplast genome. The chloroplast genome of A. alnifolia has a circular structure with a length of 159,855 bp, which includes a small single-copy region (19,409 bp), a large single-copy region (87,628 bp), and two inverted repeats (26,409 bp). The sequence had 130 genes, including 85 protein-coding genes, eight rRNA genes, and 37 tRNA genes, and the overall GC content was 36.6%. The genes trnK-UUU, rps16, trnG-UCC, atpF, rpoC1, trnL-UAA, trnV-UAC, petB, petD, rpl16, rpl2, ndhB, trnI-GAU, trnA-UGC, and ndhA contained one intron; genes clpP and ycf3 contained two introns. Phylogenetic results showed that A. alnifolia had the closest relationship with Sorbus folgneri (MK161058).
Biomechanical Role of Epsin in Influenza A Virus Entry

Influenza A virus (IAV) utilizes clathrin-mediated endocytosis for cellular entry. Membrane-bending protein epsin is a cargo-specific adaptor for IAV entry. Epsin interacts with ubiquitinated surface receptors bound to IAVs via its ubiquitin interacting motifs (UIMs). Recently, epsin was shown to have membrane tension sensitivity via its amphiphilic H0 helix. We hypothesize this feature is important as IAV membrane binding would bend the membrane and clinical isolates of IAVs contain filamentous IAVs that may involve more membrane bending. However, it is not known if IAV internalization might also depend on epsin’s H0 helix. We found that CALM, a structurally similar protein to epsin lacking UIMs shows weaker recruitment to IAV-containing clathrin-coated structures (CCSs) compared to epsin. Removal of the ENTH domain of epsin containing the N-terminus H0 helix, which detects changes in membrane curvature and membrane tension, or mutations in the ENTH domain preventing the formation of H0 helix reduce the ability of epsin to be recruited to IAV-containing CCSs, thereby reducing the internalization of spherical IAVs. However, internalization of IAVs competent in filamentous particle formation is not affected by the inhibition of H0 helix formation in the ENTH domain of epsin. Together, these findings support the hypothesis that epsin plays a biomechanical role in IAV entry.
An ionic liquid / bismuth film-modified sensor for the electrochemical detection of cefixime

A highly sensitive and simple method based on an ionic liquid/ex situ bismuth film-modified single-use pencil graphite electrode (IL/Bi/PGE) was offered for the electrochemical detection of cefixime (CEF) for the first time. The synergistic effects of the ionic liquid and bismuth film combination as the surface modifier remarkably improved the electrochemical response of the modified sensor. Anodic oxidation of CEF was observed at 0.9 V vs. Ag/AgCl/3 M KCl as one well-defined irreversible oxidation peak. Under optimum experimental conditions, the IL/Bi/PGE exhibited a linear relationship for CEF concentrations in the range of 0.005–0.5 μM (R = 0.996) with a detection limit as 0.22 nM with square wave voltammetry. The IL/Bi/PGE had excellent sensor properties to electrochemically detect CEF when compared to the literature. This method was successfully applied for practical use with pharmaceutical samples by standard addition method with high accuracy. These results showed that this simple analytical method can find potential application in the clinical field instead of highly expensive and time-consuming processes.
Comparative studies of genomic and epigenetic factors influencing transcriptional variation in two insect species

Abstract Different genes show different levels of expression variability. For example, highly expressed genes tend to exhibit less expression variability. Genes whose promoters have TATA box and initiator motifs tend to have increased expression variability. On the other hand, DNA methylation of transcriptional units, or gene body DNA methylation, is associated with reduced gene expression variability in many species. Interestingly, some insect lineages, most notably Diptera including the canonical model insect Drosophila melanogaster, have lost DNA methylation. Therefore, it is of interest to determine whether genomic features similarly influence gene expression variability in lineages with and without DNA methylation. We analyzed recently generated large-scale data sets in D. melanogaster and honey bee (Apis mellifera) to investigate these questions. Our analysis shows that increased gene expression levels are consistently associated with reduced expression variability in both species, while the presence of TATA box is consistently associated with increased gene expression variability. In contrast, initiator motifs and gene lengths have weak effects limited to some data sets. Importantly, we show that a sequence characteristics indicative of gene body DNA methylation is strongly and negatively associate with gene expression variability in honey bees, while it shows no such association in D. melanogaster. These results suggest the evolutionary loss of DNA methylation in some insect lineages has reshaped the molecular mechanisms concerning the regulation of gene expression variability.
Some Factor Affecting the Trend of Aggressive Behavior of Adolescents in the Tourist Areas in Kuta Bali

The purpose of this study is to determine the effect of peer group interaction, and the interaction of adolescents with tourists on the tendency of aggressive behavior of adolescents in Bali's tourist areas. By using the stratified random sampling technique, the examined sample had as many as 180 people. Data were collected through questionnaires. The data were analyzed using the multiple correlation analysis. The results showed that the interaction of peer groups and the interaction of adolescents with tourists significantly influenced the tendency of aggressive behavior, which means that the variations in the tendency of aggressive behavior were caused by peer group interaction and by the interaction of adolescents with tourists.
Design of a Variable Stiffness Gecko-Inspired Foot and Adhesion Performance Test on Flexible Surface

Adhesion robots have broad application prospects in the field of spacecraft inspection, repair, and maintenance, but the stable adhesion and climbing on the flexible surface covering the spacecraft has not been achieved. The flexible surface is easily deformed when subjected to external force, which makes it difficult to ensure a sufficient contact area and then detach from it. To achieve stable attachment and easy detachment on the flexible surface under microgravity, an adhesion model is established based on the applied adhesive material, and the relationship between peeling force and the rigidity of the base material, peeling angle, and working surface stiffness is obtained. Combined with the characteristics of variable stiffness structure, the adhesion and detachment force of the foot is asymmetric. Inspired by the adhesion-detachment mechanism of the foot of the gecko, an active adhesion-detachment control compliant mechanism is designed to achieve the stable attachment and safe detachment of the foot on the flexible surface and to adapt to surfaces with different rigidity. The experimental results indicate that a maximum normal adhesion force of 7.66 N can be generated when fully extended, and the safe detachment is achieved without external force on a flexible surface. Finally, an air floating platform is used to build a microgravity environment, and the crawling experiment of a gecko-inspired robot on a flexible surface under microgravity is completed. The experimental results show that the gecko-inspired foot with variable stiffness can satisfy the requirements of stable crawling on flexible surfaces.