Miracle-dz/UniFAR-FTUs huggingface dataset:
Safety and immunogenicity of Salmonella typhi Ty21a liquid formulation vaccine in 4- to 6-year-old Thai children.

All 28 serum samples were then tested blindly for the presence of HCV RNA sequences by a standard HCV RNA reverse transcription-nested PCR protocol [2]. In accord with our previous experience with diagnosing human immunodeficiency virus by PCR [3], we tested samples with two sets of primers (two inand two out-primers), both coding for sequences in the 5' noncoding region of the HCV genome [I, 2]. Samples were considered reactive if they showed one positive result out of two amplifications. Positive samples were those that showed two positive results after amplification with the two primer sets (table I). Ifone considers that all samples showing at least one positive PCR result are viremic, a good correlation can be established between PCR and RIBA-2 results. Five samples were PCRand RIBA-positive. Four were PCR-reactive and RIBA-positive. Although reactive samples were generally positive with one primer set, the use ofa second set made it possible to detect reactivity in I more patient. This fact enforces our theory that multiple primer pairs should be routinely used for virus diagnostic purposes. In four samples we had completely different results from both assays (samples 3, 16, 18, and 28). The great divergence of results between the EIA tests from two manufacturers (Ortho and Abbott) with samples 3 and 16 (RIBA-negative, PCR-positive) is notable. Both samples showed high ratios of OD cutoff (;;::::4.8) with the Ortho test; in contrast, ratios were ~0.17 with the Abbott test. In these cases, the 4 patients must be followed longer to establish the reason(s) for the divergent results: The RIBA-positive, PCR-negative results may be due to low virus production, genomic divergence of the isolate, or even false positivity of the RIBA; the RIBA-negative, PCR-positive results may be due to low antibody production by the patient or false positivity of the PCR assay.
NASGRO 3.0 - A SOFTWARE FOR ANALYZING AGING AIRCRAFT

Structural integrity analysis of aging aircraft is a critical necessity in view of the increasing numbers of such aircraft in general aviation, the airlines and the military. Efforts are in progress by NASA, the FAA and the DoD to focus attention on aging aircraft safety. The present paper describes the NASGRO software which is well-suited for effectively analyzing the behavior of defects that may be found in aging aircraft. The newly revised Version 3.0 has many features specifically implemented to suit the needs of the aircraft community. The fatigue crack growth computer program NASA/FLAGRO 2.0 was originally developed to analyze space hardware such as the Space Shuttle, the International Space Station and the associated payloads. Due to popular demand, the software was enhanced to suit the needs of the aircraft industry. Major improvements in Version 3.0 are the incorporation of the ability to read aircraft spectra of unlimited size, generation of common aircraft fatigue load blocks, and the incorporation of crack-growth models which include load-interaction effects such as retardation due to overloads and acceleration due to underloads. Five new crack-growth models, viz., generalized Willenborg, modified generalized Willenborg, constant closure model, Walker-Chang model and the deKoning-Newman strip-yield model, have been implemented. To facilitate easier input of geometry, material properties and load spectra, a Windows-style graphical user interface has been developed. Features to quickly change the input and rerun the problem as well as examine the output are incorporated.
The Use of Dexmedetomidine on Pediatrics Undergoing Magnetic Resonance Imaging (MRI) Examination

various beneficial physiological effects and now has been widely used as an off-label agent in various procedures and age groups, including as a sedative agent for pediatrics that are going to have magnetic resonance imaging (MRI) examination, which requires sufficient deep sedation without disturbing airway patency. The use of dexmedetomidine as a sedative agent in infants undergoing MRI examinations will be the scope of this review.
RISE IN 2017–2018 MEASLES MORBIDITY IN SERBIA AND NORTHWEST RUSSIA

In 2017, the WHO registered 23,927 measles cases in 44 out of 53 countries in the European region. In 2018, measles incidence rate increased up to 82,599 cases registered in 48 countries of the region, with a large number of measlesassociated deaths. Overall, 72 measles fatalities were registered in 10 European countries, including Serbia (15 cases). Aim of the study: to characterize 2017–2018 epidemiological upsurge of measles incidence rate observed in the Republic of Serbia (RS) and the Northwestern Federal District (NWFD) of the Russian Federation. Materials and methods. During the 2017–2018 season, 944 serum samples were collected from patients with measles, rubella, or exanthematous diseases in the NWFD and tested in the Laboratory of Virology at the St. Petersburg Regional Centre for Measles Surveillance (SPbRC). In 2017–2018, 2,946 serum samples from the Republic of Serbia were analyzed in the SPbRC by using ELISA with IgM measles test system (Vector-Best, Russia; or Siemens, Germany). Urine and swab samples were examined by RT-PCR and used for isolation and genotyping of measles viruses. Results. From 2017 to 2018, 5,798 measles cases were registered in the RS, among which 2,946 were laboratory-confirmed (serological testing and/or PCR). Unvaccinated subjects or those with unknown vaccination status accounted for majority of the cases. Children under 5 years of age and adults aged 30 years and over dominated among measles patients. During this season, 15 deaths were reported. Several genotypes of measles virus circulated in the RS, e.g. В3 Dublin, D8 Gir Somnath, and D8 Herborn. In 2018, 109 measles cases were recorded in the NWFD, 5 of which were imported from abroad. Among patients, adults comprised 64.2%, wherein 74.3% were covered by unvaccinated subjects or those with unknown vaccination status. Rise in measles incidence rate linked to multiple importations of various measles virus genotypes: В3 Kabul; B3 Dublin; D8 Frankfurt; D8 Cambridge; and D8 Gir Somnath.
THE ABILITY TO IDENTIFY MARKET OPPORTUNITIES AND THE DEVELOPMENT OF SMALL BUSINESSES

M odern enterprises, especially small1 ones, operating in a turbulent and uncertain environment, seek more effective competitive advantages. The success of these activities is dependent to a large extent on the entrepreneurial behaviour of a given company. The level and intensity of entrepreneurial behaviour vary and often depend on the entrepreneurial capacity. The intensity of entrepreneurship changes under the influence of various conditions of an internal nature based on company resources, e.g.: human resources, tangible assets, research and development facilities or knowledge, as well as external conditions resulting from the impact of the environment. The conditions of contemporary market competition pose new challenges for these entities in terms of improving the efficiency of business operations, requiring focus on the development of dynamic capabilities and identification of market opportunities. Dynamic capabilities may become a source of a temporary competitive advantage, among others, through manufacturing of distinctive products, development of new markets and reconfiguration of resources. The goal of these activities is increasing the speed and degree of identifying new market opportunities. Therefore, the aim of the paper is to assess the impact of the enterprise’s ability to identify market opportunities on its development. To accomplish this goal, the following research hypothesis was adopted: There is a relationship between the level of enterprise’s ability to identify market opportunities and its development. The first part of the paper discusses the concept of enterprise growth and development, with particular emphasis on small businesses specificity, and then indicates the main attributes of entrepreneurial orientation, dynamic capabilities and identification of market opportunities in the context of inducing the development of these entities. The second part presents the research methodology and characteristics of the research sample. The last part of the paper presents the results of the research carried out on a sample of 400 small innovative enterprises operating in Poland. The main conclusions are indicated in the last part of the paper along with research limitations and directions of further research. THE ABILITY TO IDENTIFY MARKET OPPORTUNITIES AND THE DEVELOPMENT OF SMALL BUSINESSES
Soil Salinity Variation in Rows Mulched with Plastic Film and Uncovered Intervals in Cotton

A field experiment was carried out with many Type 5500 salinity sensors used to monitor soil salinity variation in rows mulched with plastic film and in uncovered intervals. The results can be described as follows: (1) The salinity at soil surface, at 10 cm and 30 cm under surface changes obviously with similar pattern. Soil salinity decreased noticeably after an irrigation and increased gradually during irrigation interval. The salt leaching processes at all monitoring points are similar during an irrigation. But soil salinity at part mulched with plastic film increased quickly than that at uncovered intervals. The soil salinity at 10 cm under surface, both under plastic films in uncovered intervals, changed obviously during rain. But the change range in intervals is much larger than that under plastic films. (2) there is not noticeable salt accumulation at 60 cm soil layer under surface, regardless under plastic film or under uncovered intervals. Soil salinity decreased gradually with irrigation. The declining ranges in uncovered intervals is larger than that under plastic films.
A Novel Mode of Chaperone Action HEME ACTIVATION OF Hap1 BY ENHANCED ASSOCIATION OF Hsp90 WITH THE REPRESSED Hsp70-Hap1 COMPLEX*

Molecular chaperones Hsp90 and Hsp70 control many signal transducers, including cyclin-dependent kinases and steroid receptors. The yeast heme-responsive transcriptional activator Hap1 is a native substrate of both Hsp90 and Hsp70. Hsp90 and Hsp70 are critical for the precise regulation of Hap1 activity by heme. Here, to de-cipher the molecular events underlying the actions of Hsp90 and Hsp70 in heme regulation, we purified various multichaperone-Hap1 complexes and characterized the complexes linked to Hap1 repression and activation by two-dimensional electrophoresis analysis. Notably, we found that in vitro Hap1 is associated continuously with Ssa and its co-chaperones, and this association is not weakened by heme. Heme enhances the interaction be-tween Hap1 and Hsp90. In vivo , defective Ssa, Ydj1, or Sro9 function causes Hap1 derepression in the absence of heme, whereas defective Hsp90 function causes reduced Hap1 activity at high heme concentrations. These results show that continuous association of Hap1 with Ssa, Ydj1, and Sro9 confers Hap1 repression, whereas enhanced association of Hsp90 with the repressed Hap1-Ssa-Ydj1-Sro9 complex by heme causes Hap1 activation. This novel mechanism of chaperone action may operate to control the activity of other important signal transducers. Molecular
Methodology for assessing the grain mass thermal effusivity in a metal silo under the influence of active ventilation

The purpose of studying the thermal effusivity of the grain mass in a metal silo is to obtain a dynamic mathematical model of the processes of laye red changes in the temperature of the grain mass un der the influence of an external factor. Such an extern al factor is the supply of cooling air through the air distribution grid of the bottom of the silo with th e active ventilation of grain in a metal silo. The cr ated mathematical and parametric models allow simulating the moisture transfer process using active air ventilation systems inside metal silos during stora ge of wheat grain. There have been developed some w ays to improve the conditions for ensuring the quality preservation of grain during its long-term storage in a metal silo. It is necessary to load such a silo wit h grain completely, preferably up to the top, leavi ng free supergrannial space as small as possible. Another s olution is thermal insulation of the surfaces of th e silo. The task of ensuring the safety of wheat food grain c be accomplished not only on the basis of exist ing regulatory rules, but also by taking into account t he results of new research. The main method of stor age in metal containers, according to the instructions and safety regulations is the storage of grain in a dr y and purified state. It is known that not only humidity and purity, but also the temperature of the grain p ut into storage affect the storage period.
Scientific-based approach pictorial storybook for eliciting creative thinking and collaborative skills

This research aimed to develop a picture-story book based on scientific approach through the discovery learning method to improve students’ creative thinking and collaborative skill. This research was a research and development which adopted a model proposed by Borg & Gall which step including (1) research and information collecting, (2) planning, (3) developing preliminary product, (4) preliminary field testing, (5) main product revision, (6) main field testing, (7) operational product revision, (8) operational field testing, (9) final product revision, and (10) dissemination and implementation. The subject consisted of 50 students from the experimental class and 25 students from the control class. The result showed that (1) the picture-story book based on scientific approach through discovery learning method developed valid for use based on expert assessment and test result at the school with “very good” category, (2) the picture-story book based on scientific approach through discovery learning method could be used to improve students’ creative thinking and collaborative skills.
The development of homogeneity psycho cognition learning strategy in physical education learning

Received Feb 10, 2021 Revised Jul 12, 2021 Accepted Jul 20, 2021 Many future studies have been developed by scientists today in the form of methods, models, strategies, and techniques in improving student learning outcomes that are oriented to psychology and the development of students' intelligence. One of the latest innovations in learning offered in this study is the homogeneity psycho cognition (HPC) strategy. The research objective was to develop the latest learning strategies in physical education, sports, and health learning. This development research uses a 4D model consisting of four stages: define, design, develop, and disseminate to produce products in the form of an HPC learning strategy. This study involved 115 elementary school students in several sample schools in Ambon City as participants. This study found that the HPC learning strategy had been developed following the relevant development directions and procedures. The validation of the HPC strategy by experts indicates that the HPC strategy is feasible to implement with due regard to minor revisions. The results of small and medium-scale trials show that the HPC strategy can improve student learning outcomes.
Juntendo Medical Journal

We live in a modern era where researchers are expected to undertake high-quality research to address the growing challenges that our global society faces. Contemporary neuroscience demands experimental approaches that can relate anatomical and functional studies. To this end, it is necessary to perform a technical tour de force study to understand the relationship between the structure and the function of the brain. In this paper, I review some of the tools currently available to neuroscientists to study brain both at the circuit and synaptic level. The wealth of information that can be harnessed by incorporation of multiple research techniques will ultimately prove useful to tackle many societal issues, including the development of novel therapeutics to treat neurological diseases.
Development of an UAVS distribution tools for pest's biological control “Bug Bombs !”

This paper describes the development of an UAV system customized to be an alternative tool employed on the pest's combat using biological control (e.g., applied over soybean, corn, bean (crops types)). This control uses the pest's natural enemy, distributing them on the fields (through an aerial way) to combat and eliminating the pest's without the use of poison (chemical), improving the agriculture production and increasing the food quality. For this work we are considering the use of a biological control agent called by Trichogramma Pretiosum and your use over soybean crops. The UAVS developed allows the operator to remotely fly and control the aircraft from a one-man portable ground station, considering a pre-defined mission over the crops. The text describes the development of the electrically propelled airborne part of the UAV system, including the aircraft, the assembling of the onboard hardware, the payload development, one-man portable ground station components and software, and the integration of their subsystems. An overview of system works considering a fictitious scenario was used to demonstrate the stages of the biological control process applied over the crops. The main conclusion is that this tested tool system proves it possible to employ an UAVS an alternative toll employed on the pest's biological control.
Improving automation delivery project quality with quality gate project model

HUJANEN, HENRIIKKA: Tampere University of Technology Tampere University of Technology Master of Science Thesis, 85 pages, 1 Appendix page May 2016 Master’s Degree Programme in Energy technology Major: Safety technology and Environmental management Examiners: Professor Jouni-Kivistö Rahnasto and Assistant Prof. Teemu Laine
Hierarchical Mapping

Mobile robots need to be fully autonomous in order to perform their tasks inside their environment. To do that, robots need to have an understanding of their environment, so that they can successfully localize and navigate themselves within it. The understanding of the robots’ environment is created by solving the SLAM (Simultaneous Localization And Mapping) problem. The SLAM problem is usually approached using probabilistic laws; both the robot’s path and the environment are estimated and represented by probability distributions. The estimate of the environment is incorporated into a map, which could either be one global map or a network of smaller connected local maps. In small areas where the sensors’ errors and inaccuracies remain low, the creation of one global map is preferred. However, as the area grows larger, the global map becomes inaccurate due to accumulated errors. Therefore the strategy of creating a network of local maps is employed. Even though this strategy produces low error results, there is still a limit beyond which it does not scale. Specifically, as the mapping area grows even wider, the number of local maps increases which in turn causes the amount of required memory to increase. In addition, when it comes to loop closure or in other words the procedure of estimating whether the robot returned to a previously visited point in the map, the required computational power increases linearly or sometimes quadratically with respect to the number of local maps. Consequently, SLAM algorithms suffer from scalability problems, especially when the mapping area becomes too large. Since robots are real-world devices, mapping solutions should be efficient and applicable to the robot’s resources, even when these resources are limited. In this thesis we propose a framework which addresses this scalability issue, aiming to reduce the computational needs and memory usage during the SLAM procedure. Additionally, our framework intends to facilitate loop closure, which can become troublesome in large environments. Our framework uses multiple sensors and creates a network of hierarchically structured local maps. In order to assess our framework, we compare it to a technique which produces a network of nonhierarchically structured local maps. Our experiments show that in large areas our framework works ideally; the speedup is encouraging and the RAM memory overhead is negligible or conditionally lower.
GUIDELINES FOR FOR THE EASTERN STATES*

Guidelines for the determination of earthquake ground-motion definition for the eastern United States are established in this paper. Doth far-field and near-field guidelines are given. The guidelines Here based on an exten- sive review of the current procedures for specifying ground motion in-the United States. Both empirical and theoretical procedures were used in estab- lishing the guidelines because of the low seismicity in the eastern United States. Only a few large to great (M > 7.5) sized earthquakes have occurred in this region, no evidence of tectonic surface ruptures related to historic or Holocene earthquakes have been found, and no currently active plate bound- aries of any kind are known in this region. Very little instrumented data has been gathered in the East. Theoretical procedures- are proposed so that in regions of almost no data a reasonable level of seismic ground motion activity can be assumed. The guidelines are to be used to develop the Safe Shutdown Earthquake, SSE. A new procedure for establishing the Operating Basis Earthquake, OBE, is proposed, in particular for the eastern United States. The QBE would be developed using a probabilistic assessment of the geological condi-. tions and the recurrence of seismic events at a site. These guidelines should be useful in development of seismic design requirements for fu~. ure reactors. Abstract Guidelines, for the determination of earthquake ground-motion definition for the eastern United States are established in this paper. Both far-field and near-field guidelines are given. The guidelines were based on an exten- sive review of the current procedures for specifying ground notion in the United States. Both empirical and theoretical procedures were used in estab- lishing the guidelines because of the low seismicity in the eastern United f ates. Only a few large to great (M > 7.5) sized earthquakes have occurred in this region, no evidence of tectonic surface ruptures related to historic or Holocene earthquakes have been found, and no currently active plate bound- aries of any kind are known in this region. Very little instrumented data has been gathered in the East. Theoretical procedures are proposed so that in regions of almost no data a reasonable level of seismic ground motion activity can be assumed. The guidelines are to be used to develop the Safe Shutdown Earthquake, SSE. A new procedure for establishing the Operating. Basis Earthquake, OBE, is proposed, in particular for the eastern United States. The OBE would be developed using a probabilistic assessment of the geological conditions and the recurrence of seismic events at a site; These guidelines should be useful in development of seismic design requirements for future reactors.