Miracle-dz/UniFAR-FTUs huggingface dataset:
Efficacy of Qurs-e-Gulnar in Ziabetus (type 2 Diabetes Mellitus): a single blind randomized controlled trial

Abstract Background and objectives Diabetes is a serious threat to global health that respects neither socioeconomic status nor national boundaries. Globally, diabetes is among the top 10 causes of death. Unani system argued the effectiveness of several anti-hyperglycemic drugs, and all such drugs looked-for to be validated on scientifically. Hence a clinical trial was contemplated to evaluate the clinical efficacy of Qurs-e-Gulnar in the management of Diabetes Mellitus. Methods This study was conducted as single blind randomized control, on 40 patients of type 2 diabetes with the test (n=20) and control (n=20) groups for 45 days. Test group received Qurs-e-Gulnar at the dose of three Qurs twice a day, and control group received two capsules Diabeat® twice a day before meal. Subjective (at 0, 15th, 30th, and 45th) and objective parameters were assessed as pre-post treatment respectively. Results After treatment with test compound significant reduction was observed in all the subjective parameters viz. polyuria, polydipsia, polyphagia and tiredness in comparison of control group. The objective parameters FBS and PPBS was found to be significantly reduced (p<0.001) in both the groups where as HbA1c was found unchanged in test group but control drug showed highly significant reduction in HbA1c (p<0.001). The results were assessed statistically using two tailed Student’s t-test, and Fischer exact test. Conclusion On the basis of above observation it is concluded that the test compound Qurs-e-Gulnar has significant anti-diabetic effect which is evidentially observed both in subjective and objective parameters in test group in comparison of control group (CTRI/2017/07/009060).
Unification of Internal Resistance Estimation Methods for Li-Ion Batteries Using Hysteresis-Free Equivalent Circuit Models

Internal resistance is one of the important parameters in the Li-Ion battery. This paper identifies it using two different methods: electrochemical impedance spectroscopy (EIS) and parameter estimation based on equivalent circuit model (ECM). Comparing internal resistance, the conventional parameter estimation method yields a different value than EIS. Therefore, a hysteresis-free parameter identification method based on ECM is proposed. The proposed technique separates hysteresis resistance from the effective resistance. It precisely estimated actual internal resistance, which matches the internal resistance obtained from EIS. In addition, state of charge, open circuit voltage, and different internal equivalent circuit components were identified. The least square method was used to identify the parameters based on ECM. A parameter extraction algorithm to interpret impedance spectrum obtained from the EIS. The algorithm is based on the properties of Nyquist plot, phasor algebra, and resonances. Experiments were conducted using a cellphone pouch battery and a cylindrical 18650 battery.
Discovery of functional iridescence and its coevolution with eyes in the phylogeny of Ostracoda (Crustacea)

Highly efficient iridescence caused by natural diffraction gratings is reported for the first time in the Crustacea. Iridescence presumably began as an epiphenomenon, but has evolved to include a courtship function in at least some myodocopid Ostracoda (Crustacea). Ostracod iridescence apparently preceded the evolution, and is probably a precursor, of cypridinid (Myodocopida) bioluminescence. By tracing the development of light reception and display, myodocopid evolution, in part at least, is revealed. Therefore, light appears to be the main stimulus to myodocopid evolution. The myodocopid lateral eye probably evolved at a similar point in time as iridescence, possibly to detect iridescence. The graduations by which the ostracod compound eye has developed are suggested. These findings challenge current theories which demand a single evolution of the compound eye.
GEOGRAPHIC VARIATION IN THE MORPHOLOGY OF CROTALUS HORRIDUS (SERPENTES: VIPERIDAE)

ABSTRACT The timber rattlesnake (Crotalus horridus) occurs in discontinuous populations across the eastern and central United States. The species exhibits high levels of polymorphism in morphological traits, especially in coloration and pattern. Previous studies recognized either distinct northern and southern subspecies or three regional morphs (northern, southern, and western), but the conflicting data sets and limited geographic sampling of previous studies have left the relationships among those regional variants unclear. In this study, univariate and multivariate statistics, analyzed in conjunction with a geographic information system, were used to examine geographic variation in 36 morphological characters recorded from 2420 specimens of C. horridus across its range. Univariate analyses detected substantial geographic variation in all meristic characters. Scutellation exhibited a general north–south pattern of variation, and most scale counts averaged higher in southern regions. Pattern characters differentiated the northeastern, central-eastern, and north-central regions from the southern and western regions. Coloration displayed a pattern of strong clinal variation among three broad areas consisting of the combined northeastern, central-eastern, and southern Appalachian regions, the northwestern regions, and the southern regions. Morphometric characters exhibited a general north–south pattern of geographic variation, with larger head and body sizes in southern regions. Sexual dimorphism was strong in ventral and subcaudal scales, and weak to moderate in band length and band spacing. Principal component analysis indicated that band length was the most important variable for characterizing geographic variation. The northeastern regions remained moderately distinct in all multivariate cluster analyses. The northwestern regions appeared very distinct in most cluster analyses for females. However, the clusters in all models showed extensive geographic overlap. Maps of the clusters revealed two north–south patterns of clinal variation across the northeastern, northwestern, and southern regions. The discordant patterns of variation among individual characters, overlapping patterns of coloration, and extensive overlap among the multivariate clusters collectively indicate that the putative zones of intergradation among recognized subpopulations of C. horridus are much broader than previously thought. Furthermore, because the general patterns of geographic variation are strongly clinal, our results support the conclusion that C. horridus is a single widespread species with variation too extensive and complex to be reflected by formal subspecific designations.
Leaf nutrient composition, its correlation with yield and quality of sweet orange and soil microbial population as influenced by INM in Vertisol of central India

A field trial was conducted on eight-year-old sweet orange orchards grown on black soils for three years under central Indian conditions. Different treatments involved application of FYM, vermi-compost, wheat straw on nitrogen equivalent basis and green manuring with sun hemp as singly or in combination with inorganic or biofertilizers like Azotobacter and PSB including control plots. The results showed highest concentration of N (2.19%), P (0.111%), K (1.38%), Mg (0.302%), Zn (26.3 ppm) and Cu (16.2 ppm) in the leaves with the combined application of FYM along with 50% dose of inorganic fertilizers and Ca (2.51%) with green manuring with sun hemp along with 50% dose of inorganic fertilizers. Sole application of FYM (to supply 100% N) recorded highest Mn (75 ppm) and Fe (155 ppm) contents followed by combined application of FYM (to supply 75% N) along with Azotobacter and PSB. Significant positive correlation was observed between leaf macronutrients content and fruit yield while leaf Zn content with both yield and quality of fruits. Soil bacterization with Azotobacter and PSb increased their abundance, multiplied well and were able to save 25 per cent dose of organic manures or fertilizers applied for N and P nutrition. Organic manures were highly effective in increasing the microbial population in the soil.
A Scholar-Practitioner Perspective on a Leadership Development Program in Health Care: Integrating Connectivism Theory

The Problem The U.S. health care system is currently undergoing reform, shifting from a volume to a value-based model. This transformation calls for strong leadership among physicians; however, they are often not prepared for leading changes for multiple reasons. Furthermore, physicians can be a challenging group to train when it comes to nonmedical disciplines. Therefore, identifying what will engage physicians in learning nonclinical topics is crucial for effective leadership development. The Solution I attempt to discuss this aspect by utilizing a year-long leadership development program, which yielded great response from physicians in terms of perceived value of learning. Exploring a more recent learning theory (connectivism) that considers the role of building personal learning networks (PLNs), I describe how the program unfolded and how the slow but steady emergence of PLNs became the basis for the learning. I also illustrate how theory has been used to guide program development, leading to successful outcomes. The Stakeholders Scholar-practitioners within human resource development (HRD), and leadership development professionals can be inspired to apply connectivism as a lens to further understand adult learning theories in the era of information and technology as well as apply to the development of leadership programs aimed at highly skilled professional groups.
Extended Hybrid Wind Power Forecasting Approach to Short-Term Decisions

The advantages of wind power integration over other renewable resources are well-known information and the natural results are the massive worldwide integration. Such massive integration, without the correct management together with conventional generation leads to an augmented complexity and the inflexibility of conventional power systems. For several reasons, forecasting tools are one of the most valuable tools in the power systems field, because they helps to decide in advance the way to manage correctly and with profits the electrical mix production. In this work, an extended hybrid wind power forecasting approach, with probabilistic features, is proposed to forecast twenty-four hours-ahead, considering only real historical wind power data. To validate the proposed forecasting approach, a comparison with other validated models is performed to offer a fair and proportional analysis. The outcomes show that the suggested forecasting approach performs adequately even considering the reduced data available as input.
Investigation Studies of DC-DC Boost Converter With Proportional-Integral-Derivative Controller Using Optimization Techniques

The DC to DC converter is a combination of reactive components and power devices, and widely used to desired current and voltage level efficiently. Consequently, this category of converters needed an accurate controller to control its static and dynamic performance. Proportional Integral Derivative controller parameters are commonly functional to the DC to DC converter due to its straightforwardness. Design of controller is identifying as an optimization method to achieve desired dynamic response with the help of several algorithms, e.g. optimization method based on bacterial foraging (called BFO) and particle Swam (called PSO), genetic algorithm (GA). The optimization method is based on judgement and relating achievable solutions until we do not get a better solution. The algorithm used for optimization can find many prime results. In this paper, the DC to DC boost converter is investigated with different optimization technique, e.g. GA, PSO, and BFO algorithms. Numerical Matrix laboratory 9.1 (R2016b) simulation results are provided, and various parameters of the controller, e.g. time taken for settle and rise the waveform, the peak is investigated from the step response curves. The response of the controller also compared in detail, and it can be concluded that BFA techniques are giving a better response when compared to another method.
Quantum Dot Probes for Tracking Nerve Growth Factor Ligand-Receptor Dynamics in Live Neurons

The mechanisms by which cell-surface receptors interact with their specific ligands to initiate signaling cascades is a dynamic process which involves ligand-receptor binding, transport, and clearance across and within the cell plasma membrane. Nerve growth factor (NGF) is a neurotrophin that plays a significant role in neural survival, growth and regeneration. The spatial and temporal dynamics of NGFTrkA receptor binding has been shown to be important in regulating different aspects of neurotrophin signal transduction. However, the process by which growth factorreceptor complexes are shuttled from distal axons to neuronal cell bodies is still unclear and an active area of investigation. Organic fluorophores currently used for locating receptors on neurons suffer from the drawbacks of limited spatial resolution and photobleaching. Nanometer sized, photostable quantum dots (QDs) offer the potential to track NGF-TrkA dynamics with high-resolution (molecular detection) over long periods of time. Antibody conjugated QDs have been used for labeling and tracking single receptors [1, 2]. In addition, ligand-conjugated QDs retain their activity and bind to receptors [3, 4]. In this study we employ anti-TrkA-QD antibody conjugates to visualize TrkA receptor spatio-temporal dynamics in the neuronal PC12 cell line.
Perceptions, Determinants and Residential Satisfaction from Urban Open Spaces

Quality of life as a cross-disciplinary term is explored by the sciences of urban planning and design, geography, and social sciences. The present paper: 1) investigates the factors of satisfaction of visitors to the urban open space; 2) highlights complex patterns of residents’ satisfaction from the contribution of a bioclimatic renovation project in this area. For the needs of the present, field research was conducted on the residents of a medium-sized Greek city. The urban open space chosen presents a multi-functional character, consists pole of attraction for visitors based on the variety of its uses, and encompasses a special cultural and historical identity. The methodological approach is initially based on a multi-criteria analysis (Factor Analysis) to capture the characteristics that shape the disadvantages and dynamics of urban open space in order to obtain the factors of residential satisfaction. Based on the evaluation of the satisfaction factors (Principal Components), a hierarchical classification was applied, exploring the main patterns of residential satisfaction regarding the contribution of the bioclimatic regeneration project. The findings show that residents’ satisfaction with urban open space is a function of five factors: the overall operation of the open space, the quality of leisure facilities, the contribution of the bioclimatic design of large scale project, the suitability of infrastructure for children and respect for the cultural identity of the place. The satisfaction based on the acceptance of the project of bioclimatic regeneration showed that only one in four residents is satisfied with the overall contribution of the project, while the vast majority of residents are nonetheless dissatisfied. Finally, there emerge six profiles of residents, in terms of their degree of satisfaction compared to the other interpretive variables.
Effects of Some Plant Extracts, Bioagents, and Organic Compounds on Botrytis and Sclerotinia Molds

Botrytis cinerea and Sclerotinia sclerotiorum are necrotrophic fungi and are closely related pathogenic fungi that infect hundreds of plant species worldwide. In this study, the natural botryticidal/scleroticidal efficacy of some plant extracts, bioagents, and organic compounds known to possess antifungal activity was evaluated. Pathogenicity tests of the fungal molds showed virulence divergence, depending on the isolate and host plant. All B.cinerea isolates, except the BF isolate that infected only broad bean leaves, demonstrated ability to infect detached lettuce and broad bean leaves. Moreover, all Sclerotinia sclerotiorum isolates, except for SSP, demonstrated ability to infect the two plant species, whereas the SSB isolate did not cause any infection in broad bean leaves. The efficacies ofMoringa oleifera (Mor), Cinnamomum zeylanicum (Cin), amino acid derivatives (Aad), Trichoderma harzianum (TH), Cactus spp. (Agr), and Bacillus subtilis (BS) were tested either in vitro or in vivo against the highly virulent isolates of the two pathogenic fungi. The efficacy of most potential biofungicides was consistent in vitro as well as in vivo, and the inhibitory efficacy of TH, BS, Cin, Mor, and Aad treatments was significantly high against Botrytis cinerea and Sclerotinia sclerotiorum in vitro and ranged from 62% to 100%, depending on the isolate. In addition, BS, Aad, TH, and Mor treatments had significant inhibitory effects ranging from 53% to 100% against most of the isolates on lettuce leaves. The Agr and Cin treatments exhibited low or no inhibitory effects against many isolates in vivo, and they reduced the mold infection caused by only BCC and SSB isolates. Most of the tested potential biofungicide treatments tended to reduce mold infections, and some of them, such as Cin, exhibited a higher inhibitory effect in vitro than the others. Real-time PCR was conducted for some symptomatic/asymptomatic samples, and the results showed either consistent molecular/symptomatic patterns or latency of B. cinerea. The results confirmed the suitability of the studied natural compounds as effective biofungicides, and they could be the best choice to safely control the most destructive fungal molds.
Does post-mining rehabilitation restore habitat equivalent to that removed by mining? A case study from the monsoonal tropics of northern Australia

Context Rehabilitation is increasingly being promoted as a strategy for minimising and even reversing biodiversity loss. Many rehabilitation strategies that aim to provide habitat focus entirely on establishing vegetation. Successful vegetation establishment, however, does not necessarily provide habitat that is ecologically equivalent to that removed by vegetation clearing. Quantitative understanding of faunal responses to rehabilitation is required if rehabilitation techniques are to be refined and deliver desired biodiversity outcomes. Aims I aimed to assess the extent to which post-mining rehabilitation restores bird habitat equivalent to that removed in the mining process on the Weipa bauxite plateau. Methods The composition, abundance and richness of bird assemblages were compared between native forest sites and a 23-year chronosequence of post-mining rehabilitation sites. Native forest sites were made up of three Weipa bauxite plateau land units, including the land unit that represents pre-mining native forest, and two land units that are considered to be potential analogues for the post-mining landscape. Key results Bird abundance and bird species richness increased with rehabilitation age. Bird species richness in the two oldest age classes of mine rehabilitation was similar to values obtained from pre-mining native forest and post-mining landscape analogue sites. The composition of bird assemblages, however, was significantly different. Of all the bird species observed, 25% occurred exclusively in native forest sites, 19% occurred exclusively in mine-rehabilitation sites, and the remaining 56% were recorded in both native forest and mine-rehabilitation sites. Site bird-detection rates were significantly related to site vegetation structure, with inter-specific differences in bird response. Conclusions Post-mining rehabilitation at Weipa has partially made up for the loss of habitat caused by clearing for mining. Twenty-three years after rehabilitation commenced, however, a clear residual impact on biodiversity remains, with a third of native forest birds absent from mine rehabilitation, including several native forest specialists. Implications Rehabilitation can partially make up for biodiversity losses caused by the initial loss of habitat. There is no evidence, however, that rehabilitation can achieve ‘no net loss’. Reliance on rehabilitation to achieve conservation outcomes does not address the fact that many fauna species require resources that are found only in mature forest.
When and why do negative organization-related career shocks impair career optimism? A conditional indirect effect model

PurposeThis study investigates when and why negative organization-related career shocks affect career optimism, which is a positive career-planning attitude. The indirect effect of negative organization-related career shocks on career optimism via job insecurity and the role of perceived organizational career support as a first-stage moderator were investigated.Design/methodology/approachThree-wave time-lagged data from a sample of 728 employees in Switzerland was used. Time-lagged correlations, an indirect effect model and a conditional indirect effect model with bootstrapping were used to test the hypotheses.FindingsFirst, this study showed a significant negative correlation between negative organization-related career shocks (T1) and career optimism (T3), a positive correlation between negative organization-related career shocks (T1) and job insecurity (T2) and a negative correlation between job insecurity (T2) and career optimism (T3). Second, findings revealed that negative organization-related career shocks (T1) have a negative indirect effect on career optimism (T3) via job insecurity (T2). Third, perceived organizational career support (T1) buffers the indirect effect of negative organization-related career shocks (T1) on career optimism (T3). Originality/valueThis study provides an initial examination of the relationship between negative organization-related career shocks and career optimism by applying assumptions from the JD-R model and Conservation of Resources theory. Implications about how to deal with negative career shocks in HRM and career counseling are discussed.