Miracle-dz/UniFAR-FTUs huggingface dataset:
Power-Conscious Multi-Frequency Modular Testing of SoCs with Dynamic Reconfiguration of Multi-Port ATE

With the debut of a new class of multi-port ATE (e.g., Agilent 93000 series), there is a pressing need for test planning methods to fully adapting SoC test framework design to the new concurrent test capabilities and fulfil emerging demands of high-speed testing. In this paper, we propose a new test planning strategy that addresses multi-frequency SoC testing by dynamically reconfiguring ATE ports. The system integrators on-thefly group pins into virtual ports while ATE ports simultaneously drive the testing of a set of cores at multiple independent clock domains. An effective and efficient system optimization technique is developed to manage test resources and improve test efficiency for modern complex SoC designs. keywords: Concurrent Test, Multi-Frequency SoC Test, Test Resource Partitioning, ATE Port Reconfiguration, Constrained
EFFECT OF PH ON GROWTH , PROTEIN PROFILS AND ANATOMY OF PLECTRANTHUS AMBOINICUS EXPLANTS

In this study shoot tips of P . amboinicus family Lamiaceae, were used as explant for culture in which different levels of MS(Murasige and Skoog) medium salt strength and different pH media were used. Results clearly showed that, the best nutrient media for P . amboinicus propagation in establishment of shoot formation via tissue culture was 1/10 MS salt strength medium supplemented with 75 mg/L sodium dihydrogen phosphate (NaH2PO4), 30g/L sucrose, solidified with 5 g/L agar and in presence of plant growth regulator (BA 0.1 mg/L) compared to other used treatments. Treatment with pH 5 was the best pH used for P. amboinicus planted in greenhouse; on the contrary, pH 13 decreased all the tested parameters. It was appeared clearly that, pH 4 treatment enhanced the formation of two new polypeptides (30 and 60 kDa) proteins. In contrast, synthesis of these proteins was negatively affected by the other used treatments. It was clear that pH value stress induced variations in the appearance of new protein bands and disappearance of others high molecular weights proteins, whereas no changes in low molecular weights proteins were observed. On the other hand, pH 5 induced increase in the thickness of both midvein and lamina of leaf blades of P. amboinicus. It worth noting that, the thicker lamina induced by pH 5 was mainly due to increase in thickness of chloranchyma tissue, despite the presence of a decrease in the thickness of the upper epidermis. Also, the main vascular bundle of the midvein was increased in size the increment was mainly due to the increase in the length midvein bundel than control. Key word: P.amboinicus, in vitro, MS salt strength medium, protein profiles, anatomy
Detection of the impairment of allosteric communication in Sirtuin 2 proteins through molecular dynamics and residue coevolution

Motivation Sirtuin2 is an NAD+-dependent protein deacetylase and is part of family of highly conserved enzymes. It plays a critical role to regulate several biological processes and some epigenetic mechanisms based on genome integrity-stability. Its misregulation is often related to mutations that can disrupt the deacetylase activity, making Sirtuin2 an attractive drug target for chemoprevention of some human diseases. E. coli CobB is a bacterial Sirtuin2 homologue characterized by a smaller zinc-binding domain (critical point for substrate recognition in bacteria). It was previously suggested that selective substrate-binding in CobB is mediated by distal molecular interactions between the zinc-binding domain and the pocket residues around the acetyl-lysine modified residue on the substrate [1]. The structural and functional analogies between Sirtuin2 and CobB suggest that a general mechanism of allosteric regulation could be common for Sirtuin2 proteins. However, the molecular mechanism involved in this process is still unknown [2]. Here we present a computational study based on the combined use of molecular simulations and co-evolution analysis of CobB to unveil Sirtuin2 mechanisms of substrate recognition. Using a comparative approach, we infer functional properties in Sirtuin2 and unveil analogies in the mechanisms of allosteric communication of the two proteins that could explain a conserved role of distal molecular interactions [3]. Methods The study involved three methodological steps: a) residue coevolution analysis; b) molecular dynamics simulations; c) comparative study of coevolved motions. a. A multiple sequence alignment for the sequence portion of the PDB structure 1S5P (CobB) was obtained through the MetaPSICOV webserver and used for all the analysis. Residue coevolution analysis was performed using MetaPSICOV [4] and DCA [5]. Conserved and coevolved rigid domains were detected with SPECTUSEvo [6]. b. Molecular Dynamics (MD) simulations were performed using ARCHER (UK National Supercomputing Service). Three replicas of 500ns were generated for 1S5P
Religious and Secular Paradigms of Addressing Pluralism

The following essay looks at the religious and secular paradigms of addressing pluralism. Firstly we will look at religious pluralism from a Christian standpoint, considering its three major responses: particularism, inclusivism and pluralism. Secondly we present the secular perspective on religious pluralism, examining the way secular lifestyle and secular spirituality competes with institutionalized religion. This paper argues that secular spirituality, while encouraging respect towards the study of organized religion, promotes alienation and disregard for any type of religious participation. In addition, the secular rationale cannot applied to all humanity, because a rational, ethical or religious prescription for the humankind that would be in agreement with all people does not constitute reality, and so, the world ethos remains an abstraction. Also, the paradigms offered by inclusivism and pluralism are not compatible with traditional Christianity which affirms the objectivity of the revelation of God in the Bible, through his Son Jesus Christ who we believe is the sole Savior of every culture or reli-
The Timing of Green Investments under Regime Switching and Ambiguity

The economic success of green investments does not only depend on the uncertain economic development but also on future regime switches in the relevant legislation. As a result of political decision-making the latter are assumed to be rather ambiguous than uncertain. Based on the example of biologic fuel we develop a real options model that takes into account economic uncertainty as well as political ambiguity. We calculate the option value of the green investment and derive the optimal investment-timing strategy. Furthermore, we analyze both the sole as well as the combined influence of economic uncertainty and political ambiguity on these topics.
CAPITAL STRUCTURE IN SMEs : PECKING ORDER VERSUS STATIC TRADE-OFF , BOUNDED RATIONALITY AND THE BEHAVIOURAL PRINCIPLE

In this paper, we scrutinize financing decisions in small and medium-sized firms. In the finance literature, two competing models – the static trade-off theory and the pecking order theory – try to explain the financing decisions in firms. Given the special cognitive style of management in SMEs, characterized by bounded rationality and intuition, we investigate whether the behavioural principle has a higher explanatory power than the two traditional competing theories in relation to financing behaviour in SMEs. Our analysis is conducted on a sample of 899 firms, of which financial data are collected over a 10-year period from 1993 – 2002. All firms in our sample fit the three criteria: 1) privately-owned, 2) SME criteria of the European Commission and 3) primary activity in manufacturing, wholesale or retail industry. To study the empirical significance of the behavioural principle, the static trade-off and the pecking order theory, we use several partial adjustment models. The regression results support the predictions provided by the pecking order theory that firms decrease or increase their financial debt in correspondence to the availability or lack of internal funds. EFM classification codes: 140; 800 # Corresponding author. Doctoral student. Limburg University Center, Faculty of Business Administration, Universitaire Campus-Gebouw D, B-3590 Diepenbeek, Belgium. Tel. +32/11.26. 86.31 Fax. +32/11.26. 87.00. e-mail: silvia.swinnen@luc.ac. be * Assistant professor of finance. Limburg University Center, Faculty of Business Administration, Universitaire Campus-Gebouw D, B-3590 Diepenbeek, Belgium. Tel. +32/11.26. 86.94 Fax. +32/11.26. 87.00. e-mail: wim.voordeckers@luc.ac. be ° Assistant professor of finance. Limburg University Center, Faculty of Business Administration, Universitaire Campus-Gebouw D, B-3590 Diepenbeek, Belgium. Tel. +32/11.26. 86.22 Fax. +32/11.26. 87.00. e-mail: sigrid.vandemaele@luc.ac. be
Study of Agronomical and Technological Quality Characteristics of Some Special Egyptian Rice Varieties

HIS STUDY aimed to evaluate the agronomic and technological quality characteristics of Jasmine, Waxy and Black rice varieties under Egyptian conditions during seasons 2012-2013 compared to traditional one. Jasmine rice variety out yielded other varieties and gave the highest values for yield and yield component characters. Black rice had the smallest values for yield and yield component followed by Sakha 106 characters except panicle weight which recorded the second value with both Waxy and Sahkha 106. Jasmine rice characterized by low % broken and % paddy which related to reduced grain loss. Black rice had higher antioxidant activity (70.52 % DPPH). In addition, its high nutritional value relates to its chemical and mineral contents, jasmine rice recorded the highest numerical value for most parameters and the lowest cooking time 9.33 min, husk ranged from 20.8 to 24.4% in the studied varieties while milled rice ranged 65.5-68.5% in varieties. Waxy rice had the highest 1000 kernels weight (22.7gm), the physical parameters (0.83 g/ml), 5.34% amylose and the highest gel consistency 95.1mm. Black rice recorded the highest protein content (8.69%) and minerals; 1874.8 (mg cy-3-glc/100g db) anthocynins; 716.4 (mg/GAE/100g) total phenols; 187.4 (mg quarstine/100g DW) flavonoids.
Estimating the Age at HIV Infection Retroactively in Limited Resource Settings: A Case Study of Tanzania

Estimation of HIV infection time is a crucial step in HIV/AIDS management as it can help to make informed decisions on the best intervention strategies for controlling new infections, and for taking care of the infected individuals. This study demonstrates three approaches for estimating the age at HIV infection in limited resource settings. Using HIV testing history data collected from a sample of 88 HIV positive women in Kilimanjaro region-Tanzania, we developed a model for estimating the most likely age at which HIV infection occurs for women under reproductive age. The sampled data were collected from typical poor resource settings where access to data is very challenging and the gap between last HIV negative test and first HIV positive test is wide. Formulation of the proposed model involved three steps. Through Modified Midpoint approach, we first determined the midpoint of the age at last negative HIV test and the age at first positive HIV test for each subject. Then, the average time at risk prior to infection, taken over all individuals was subtracted from each midpoint value to obtain the distribution of their estimated age at HIV infection (T). In the second step, survival analysis techniques were used to obtain the Kaplan Meier plots and Nelson Aalen cumulative hazards estimates in which the median age for HIV infection and the most risky age were estimated. The plots of Kaplan Meir survival curves for women with different marital status and levels of education helped to assess whether their age at infection were significantly different. In the third step, we used bootstrap estimation procedures to generate 200 samples of random data and obtain the bootstrap median age at HIV infection and its confidence intervals. The estimated median age at HIV infection from survival analysis approach was 28 years while from bootstrap estimation procedures was 27 years. Likewise, the Nelson Aalen cumulative hazards plot indicated that the most risky age for HIV infection is between 18-40 years while the most risky age from bootstrap estimation was 25 to 27 years. The confidence intervals obtained through bootstrap estimation approach was narrower than that obtained from the survival analysis approach, implying that the bootstrap approach gives more precise estimates. Generally, the study findings provide useful information towards the attainment of the 90-90-90 global HIV/AIDS target as it shows where to allocate more resources and establish more focused interventions for HIV/AIDS management and control.
Hybrid Online POMDP Planning and Deep Reinforcement Learning for Safer Self-Driving Cars

The problem of pedestrian collision-free navigation of self-driving cars modeled as a partially observable Markov decision process can be solved with either deep reinforcement learning or approximate POMDP planning. However, it is not known whether some hybrid approach that combines advantages of these fundamentally different solution categories could be superior to them in this context. This paper presents the first hybrid solution HyLEAP for collision-free navigation of self-driving cars together with a comparative experimental performance evaluation over the first benchmark OpenDS-CTS of simulated car-pedestrian accident scenarios based on the major German in-depth road accident study GIDAS. Our experiments revealed that HyLEAP can outperform each of its integrated state of the art methods for approximate POMDP planning and deep reinforcement learning in most GIDAS accident scenarios regarding safety, while they appear to be equally competitive regarding smoothness of driving and time to goal on average.
F-18-FDG PET/CT detected delayed endoleak in an aorto-iliac endovascular aneurysm repair (EVAR)

: We present a case of a type Ia endoleak detected by F-18-FDG PET/CT 10 years following an abdominal aorto-iliac EVAR in an 83-year-old man. The F-18-FDG PET/CT scan was performed to evaluate a solitary pulmonary nodule but in addition demonstrated unexpected blood pool activity outside of the stent graft and within the abdominal aortic aneurysm (AAA) sac, indicating an endoleak; no FDG activity should be present within the aneurysm sac following stent graft placement. A subsequent CT angiogram confirmed the endoleak. This case illustrates the value of PET/CT in unexpectedly demonstrating this serious, late complication of EVAR.
he potential benefit of using forest biomass data in addition to arbon and water flux measurements to constrain ecosystem model arameters : Case studies at two temperate forest sites

Biomass as a resource, and as a vulnerable carbon pool, is a key variable to diagnose the impacts of global changes on the terrestrial biosphere, and therefore its proper description in models is crucial. Model-Data Fusion (MDF) or data assimilation methods are useful tools in improving ecosystem models that describe interactions between vegetation and atmosphere. We use a MDF method based on a Bayesian approach, in which data are combined with a process model in order to provide optimized estimates of model parameters and to better quantify model uncertainties, whilst taking into account prior information on the parameters. With this method we are able to use multiple data streams, which allows us to simultaneously constrain modeled variables at site level across different temporal scales. In this study both high frequency eddy covariance flux measurements of net CO2 and evapotranspiration (ET), and low frequency biometric measurements of total aboveground biomass and the annual increment (which includes all compartments), are assimilated with the ORCHIDEE model version “AR5” at a beech (Hesse) and a maritime pine (Le Bray) forest site using four to five years of flux data and nine years of biomass data. When assimilating the observed aboveground annual biomass increment (AGB inc) together with net CO2 and ET flux, the RMSE of modelled AGB inc was reduced from the a priori estimates by 37% at Hesse and 69% at Le Bray, without reducing the fit to the net CO2 and ET that can be achieved when assimilating flux data alone. Assimilating biomass increment data also provides insight in the performance of the allocation scheme of the model. Comparison with detailed site-based measurements at Hesse showed that the optimization reduced positive biases in the model, for example in fine root and leaf production. We also investigated how to use stand-scale total aboveground biomass in optimization (AGB tot). However, this study demonstrated that assimilating AGB tot measurements in the ORCHIDEE-AR5 model lead to some inconsistencies, particularly for the annual dynamics of the AGB inc, partly because this version of the model lacked a realistic representation of forest stand processes including management and disturbances. © 2016 Elsevier B.V. All rights reserved. ∗ Corresponding author at: Finnish Meteorological Institute, Climate Research, . O. Box 503, FI-00101 Helsinki, Finland. E-mail addresses: tea.thum@fmi.fi (T. Thum), atasha.macbean@lsce.ipsl. fr (N. MacBean), philippe.peylin@lsce.ipsl. fr (P. Peylin), edric.bacour@lsce.ipsl. fr (C. Bacour), iego.santaren@lsce.ipsl. fr (D. Santaren), Bernard.Longdoz@ulg.ac. be (B. Longdoz), enis.Loustau@bordeaux.inra. fr (D. Loustau), philippe.ciais@lsce.ipsl. fr (P. Ciais). ttp://dx.doi. org/10.1016/j.agrformet. 2016.12. 004 168-1923/© 2016 Elsevier B.V. All rights reserved.
Unsteady MHD Boundary Layer Flow and Heat Transfer of Ferrofluids Over A Horizontal Flat Plate with Leading Edge Accretion

Article history: Received 12 September 2018 Received in revised form 12 May 2019 Accepted 20 May 2019 Available online 18 July 2019 The unsteady forced convection boundary layer flow of ferrofluids past a semi-infinite flat plate is theoretically investigated. The governing equations are transformed into uncoupled ordinary differential equations using similarity transformation. Similarity equations were solved numerically by employing the Fourth-Fifth Order Runge-Kutta Felhberg method with shooting technique. MAPLE software was used in order to obtain graphical results. This study investigates the behavior of water and kerosene suspension which contains nanoparticles of magnetite (Fe3O4) together with heat transfer analysis due to boundary layer flow. In this problem, a comparison between two different base fluids mixed magnetic particle; Fe3O4-water and Fe3O4-kerosene has been conducted. The impact of different types of volume fraction on heat transfer enhancement and fluid flow characteristics together with the effect of several leading edge and magnetic field parameters has been studied. The effects of various physical parameters on the velocity profiles, temperature profiles, skin friction and Nusselt number were investigated numerically. The obtained results of this paper are compared to regular fluid without magnetic effect and the comparison shows good agreement with the published results. It is found that, the ferrofluids velocity, temperature and heat transfer rate increases with an increase magnetic field and nanoparticles volume fraction.
Intravitreal Injections of Melanocortin Receptor 1 , 5 Agonists Prevents Neovascularization in a VEGF 165 Mouse Model of Retinopathy

Background: The present study focuses on the evaluation of the protective effect on retinal neovascularization exerted by melanocortin receptor 1–5 (MCR 1–5) agonists in a mouse model of proliferative retinopathy induced by intravitreal injection of vascular endothelial growth factor 165 (VEGF165). Methods: Intravitreal injections of the MCR1 agonist BMS-470539 and of the MCR5 agonist PG-901 were performed 7 days before the VEGF165 injection and 1 day after VEGF165 injection. Fluorescein angiography (FAG), immunohistochemical and biochemical analysis were performed at different time points during the follow up. Results: FAG showed a marked vascular tortuosity accompanied by retinal neovascularization in mice receiving VEGF165 intravitreal injection and the absence of neovascularization in mice treated with MCR 1–5 agonists, confirmed by CD34 antigen immunostaining. The biochemical analysis of retinal VEGFR2 gene and protein expression showed that MCR 1–5 agonists significantly reduced VEGFR2 levels, increasing in parallel retinal mir-150 expression. Conclusions: According to these evidences, we propose that intravitreal injections of melanocortin receptor agonists up-regulate mir-150 expression, and this consequently reduces VEGFR2 expression levels with the endpoint being the blockade of VEGF165 induced retinopathy.
Melanoma Segmentation in Dermatoscopic Images by Methods in the Space Domain

Cancer is one of the leading causes of death worldwide. The skin cancer is a condition in which malignant cells form in the tissues of the skin, melanoma being the type of skin cancer more aggressive and more deadly. Melanoma mortality rates are associated with its high potential for metastasis in later stages, spreading to other sites in the body such as the lungs, the bones or the brain, so that their early detection and diagnosis are closely related to Survival rates. Computer-aided diagnosis (CAD) systems carry out a Pre-diagnosis of skin lesions based on information regarding clinical criteria. To perform the pre-diagnostic through a CAD system, the segmentation process is carried out first of all the image of the area affected by the injury. In this work, a methodological methodology is presented in the spatial domain that allows obtaining the segmentation of the area affected by a melanoma lesion in dermatoscopic images.
INFLUENCE OF FARMING SYSTEMS ON INDICATORS OF BEEF CALVES GROWTH

The aim of this study was to evaluate growth ability of Charolais calves in different systems of farming. The observations were performed in period of 8 years (2007 2014) in one herd, which was transiting from conventional to ecological farming system. Period from 2007 to 2010 was of conventional character, 2010 to 2012 transition phase, and from 2012 to 2014 ecological phase. This transfer is directly linked to changes in cow ́s welfare and nutrition. Growth ability (live weight at birth, 120, and 210 days of age, average daily gain from birth to 120, from birth to 210, and from 120 to 210 days of age) of 518 Charolais calves was measured. Statistical analyses were performed using SAS 9.3 software, GLM procedure. The model equations contend effect of sex, number of parity, month of calves birth and type of farming system. Difference in birth weight of calves between farming systems was small and insignificant. This fact may be due to breeding system focused on easy calving. Increase of values measured in different age and average daily gains were statistical significant (P < 0.05) between conventional and ecological farming. The increase of parameters of weight and average daily gain could be largely connected with genetic progress in Charolais population in Czech Republic and following good selection of bulls to insemination and natural breeding. Nevertheless, the transition from conventional to ecological farming system did not affected growth ability of beef cattle negatively and, in contrary, results of growth improved farm economy.