Miracle-dz/UniFAR-FTUs huggingface dataset:
Traumatic Stress Responses in Mothers and Fathers to Pediatric Intensive Care Treatment: The Role of Beliefs

The aim of this study was to examine the prevalence of traumatic stress responses in parents of children treated in a pediatric intensive care unit, specifically parental beliefs about their child’s illness and their own coping self-efficacy as related to the severity of parental acute and posttraumatic stress. Archival data from a study conducted August 2004 through July 2005 in the Children’s Hospital of Philadelphia PICU were used. Two hundred and forty-five parents were assessed at 48 hours after admission, and 180 parents were assessed 3 months postdischarge. At Time 1, parents completed a screening measure assessing psychosocial factors and an acute stress disorder (ASD) questionnaire. At Time 2, parents completed a posttraumatic stress disorder (PTSD) questionnaire. Descriptive analyses examined rates of ASD and PTSD. Chisquare analyses examined gender differences in these rates. Correlations and hierarchical multiple regression analyses examined the relationships between parental risk factors and ASD and PTSD severity. Twenty-seven percent of parents developed ASD and 37% met subsyndromal criteria, with mothers endorsing higher rates of ASD. Four percent of parents developed PTSD and 14% met subsyndromal criteria, with no gender differences in these rates. Numerous psychosocial risk factors correlated with ASD symptom severity in all parents, but with PTSD symptom severity only in mothers. Maladaptive illness beliefs and low coping selfefficacy explained a significant amount of variance in ASD and PTSD symptom severity. While two specific beliefs were highly correlated with ASD and PTSD symptom severity in all parents, differences were found in the type of beliefs correlated with maternal and paternal ASD and PTSD symptom severity. Assessments and interventions should be targeted to appropriately support traumatic stress responses in PICU mothers and fathers of children in PICUs.
Amphetamine‐induced dopamine release: Duration of action as assessed with the D2/3 receptor agonist radiotracer (––)‐N‐[11C]propyl‐norapomorphine ([11C]NPA) in an anesthetized nonhuman primate

RAJESH NARENDRAN,* MARK SLIFSTEIN, DAH-REN HWANG, YUYING HWANG, ERICA SCHER, STEPHANIE REEDER, DIANA MARTINEZ, AND MARC LARUELLE Department of Psychiatry, Columbia University College of Physicians and Surgeons, New York, New York Department of Psychiatry, The New York State Psychiatric Institute, New York, New York Translational Medicine and Genetics, Drug Discovery, GlaxoSmithKline, London, United Kingdom
Poppy Tea Dependence

A patient presenting with dependence on opium poppy tea infusion is reported. Poppy tea drinking, although previously described in certain parts of the UK, rarely presents in the form of a dependence syndrome. Issues relating to the management of poppy tea dependence are discussed, including the results of existing laboratory urinalysis for drugs of abuse, the calculation of opiate dose equivalence, and the likelihood of transition (or not) from use of poppy tea to use of other opiates.
Japan Tsunami Current Flows Observed by HF Radars on Two Continents

Quantitative real-time observations of a tsunami have been limited to deep-water, pressure-sensor observations of changes in the sea surface elevation and observations of sea level fluctuations at the coast, which are essentially point measurements. Constrained by these data, models have been used for predictions and warning of the arrival of a tsunami, but to date no detailed verification of flow patterns nor area measurements have been possible. Here we present unique HF-radar area observations of the tsunami signal seen in current velocities as the wave train approaches the coast. Networks of coastal HF-radars are now routinely observing surface currents in many countries and we report clear results from five HF radar sites spanning a distance of 8,200 km on two continents following the magnitude 9.0 earthquake off Sendai, Japan, on 11 March 2011. We confirm the tsunami signal with three different methodologies and compare the currents observed with coastal sea level fluctuations at tide gauges. The distance offshore at which the tsunami can be detected, and hence the warning time provided, depends on the bathymetry: the wider the shallow continental shelf, the greater this time. Data from these and other radars around the Pacific rim can be used to further develop radar as an important tool to aid in tsunami observation and warning as well as post-processing comparisons between observation and model predictions.
TCP Congestion Control with Appropriate Byte Counting (ABC)

This document proposes a small modification to the way TCP increases its congestion window. Rather than the traditional method of increasing the congestion window by a constant amount for each arriving acknowledgment, the document suggests basing the increase on the number of previously unacknowledged bytes each ACK covers. This change improves the performance of TCP, as well as closes a security hole TCP receivers can use to induce the sender into increasing the sending rate too rapidly.
Characterization of the pilin gene of Moraxella bovis Dalton 2d and expression of pili from M. bovis in Pseudomonas aeruginosa

The pilin gene of Moraxella bovis Dalton 2d was isolated by cloning in Pseudomonas aeruginosa. The nucleotide sequence of this gene encodes a prepilin of 156 amino acid residues. When high levels of pilin were expressed from the gene in P. aeruginosa, by using the pL promoter of bacteriophage lambda inserted upstream of the coding sequence, pili which were indistinguishable from pili of M. bovis were produced.
Adenocarcinoma of the uterine cervix

Fifty patients with adenocarcinoma of the uterine cervix were evaluated retrospectively. Treatment was based on the stage and size of tumors and the overall medical condition of the patient. Radical surgery or surgery in combination with radiation therapy was employed whenever possible. The overall survival rate was 50%, with Stage IB survival 74%. Survival in Stage IB patients was adversely affected by increasing tumor grade and size. This closely correlated with a tendency of the tumors to dedifferentiate as they increased in size. Lymph node involvement increased with increasing grade of tumor as well. Survival in patients with advanced disease was dismal. Survival increased with aggressive management which should, if possible, include surgery in Stage I and II disease.
The effect of polycarbophil on the gastric emptying of pellets

The influence of the putative bioadhesive, polycarbophil, on the gastric emptying of a pellet formulation, has been investigated in three fasted subjects. The pellets were radiolabelled with technetium‐99m. Gastric emptying was measured using the technique of gamma scintigraphy. The pellets emptied from the stomach rapidly and in an exponential manner. Polycarbophil did not retard the gastric emptying of the pellets.
Partial rescue of epithelial phenotype in integrin β 4 null mice by a keratin-5 promoter driven human integrin β 4 transgene

The α6β4 integrin is a member of a family of transmembrane glycoprotein heterodimers involved in cell-to-cell and cell-tomatrix adhesion, differentiation, migration, and signal transduction (Hynes, 1992). Its expression is restricted to squamous epithelial cells (Kajiji et al., 1989), endothelial cells of intermediate blood vessels (Kennel et al., 1992), immature thymocytes (Wadsworth et al., 1992; Watt et al., 1992) and subsets of peripheral nerve cells (Feltri et al., 1994; Niessen et al., 1994a; Sonnenberg et al., 1990). This integrin has been shown to be a receptor for the laminin isoforms laminin-1 (Ln1), Ln-2, Ln-4 and Ln-5 (Lee et al., 1992; Niessen et al., 1994b; Spinardi et al., 1995), all components of the basement membrane. In basal cells of stratified epithelia α6β4 is the major Ln-5 receptor and a key constituent of specialised adhesion structures called hemidesmosomes (reviewed by Borradori and Sonnenberg, 1996). These multiprotein structures are tightly and abundantly associated with the keratin filament system. They firmly anchor the basal cells to the underlying basement membrane and thus provide the basis for dermo-epidermal attachment. Junctional epidermolysis bullosa associated with pyloric atresia (PA-JEB) is an inherited skin disease in humans recognised as a distinct clinical entity some 20 years ago (Adashi et al., 1980; Bull et al., 1980, 1983; Carmi et al., 1982). The disorder is an autosomal recessive trait, resulting in acquired skin fragility, generalised blister formation and stenosis of the pyloric sphincter (Eady and Dunnill, 1994; Eady et al., 1994; Valari et al., 1995). The dermo-epidermal separation occurs at the level of the lamina lucida and immunohistological analysis of the skin of affected individuals 3911 Journal of Cell Science 112, 3911-3922 (1999) Printed in Great Britain © The Company of Biologists Limited 1999 JCS0589
Cloud computing for energy management in smart grid - an application survey

The smart grid is the emerging energy system wherein the application of information technology, tools and techniques that make the grid run more efficiently. It possesses demand response capacity to help balance electrical consumption with supply. The challenges and opportunities of emerging and future smart grids can be addressed by cloud computing. To focus on these requirements, we provide an in-depth survey on different cloud computing applications for energy management in the smart grid architecture. In this survey, we present an outline of the current state of research on smart grid development. We also propose a model of cloud based economic power dispatch for smart grid.
A flexible protein linker improves the function of epitope‐tagged proteins in Saccharomyces cerevisiae

Epitope tagging permits the detection of proteins when protein‐specific antibodies are not available. However, the epitope tag can reduce the function of the tagged protein. Here we describe a cassette that can be used to introduce an eight amino acid flexible linker between multiple Myc epitopes and the open reading frame of a given gene. We show that inserting the linker improves the in vivo ability of the telomerase subunits Est2p and Est1p to maintain telomere length. The methods used here are generally applicable to improve the function of tagged proteins in both Saccharomyces cerevisiae and Schizosaccharomyces pombe. Copyright © 2007 John Wiley & Sons, Ltd.
TRI_tool: a web-tool for prediction of protein–protein interactions in human transcriptional regulation

Summary: The TRI_tool, a sequence-based web tool for prediction of protein interactions in the human transcriptional regulation, is intended for biomedical investigators who work on understanding the regulation of gene expression. It has an improved predictive performance due to the training on updated, human specific, experimentally validated datasets. The TRI_tool is designed to test up to 100 potential interactions with no time delay and to report both probabilities and binarized predictions. Availability and Implementation: http://www.vin. bg.ac. rs/180/tools/tfpred.php. Contact: vladaper@vinca.rs; nevenav@vinca.rs Supplementary information: Supplementary data are available at Bioinformatics online.
Efficient Multiresolution Algorithms for Computing Lightness, Shape-From-Shading, and Optical Flow

Problems in machine vision that are posed as variational principles or partial differential equations can often be solved by local, iterative, and parallel algorithms. A disadvantage of these algorithms is that they are inefficient at propagating constraints across large visual representations. Application of multigrid methods has overcome this drawback with regard to the computation of visible-surface representations. We argue that our multiresolution approach has wide applicability in vision. In particular, we describe efficient multiresolution iterative algorithms for computing lightness, shape-from-shading, and optical flow, and evaluate the performance of these algorithms using synthesized images.
Market competition, earnings management, and persistence in accounting profitability around the world

We examine how cross-country differences in product, capital, and labor market competition, as well as earnings management affect mean reversion in accounting return on assets. Using a sample of 48,465 unique firms from 49 countries, we find that accounting returns mean revert faster in countries where there is more product and capital market competition, as predicted by economic theory. Country differences in labor market competition and earnings management are also related to mean reversion in accounting returns—but the relation varies with firm performance. Country labor competition increases mean reversion when unexpected returns are positive but slows it when unexpected returns are negative. Accounting returns in countries with higher earnings management mean revert more slowly for profitable firms and more rapidly for loss firms. Thus earnings management incentives to slow or speed up mean reversion in accounting returns are accentuated in countries where there is a high propensity for earnings management. Overall, these findings suggest that country factors explain mean reversion in accounting returns and are therefore relevant for firm valuation.
Data Preparation by CFS an Essential approach for decision making using C 4 . 5 for Medical data mining

Trauma has become the leading cause of death in day to day life. Every year millions of people die and many more are handicapped due to various types of accidents caused by Trauma and many people become handicapped for the rest of their lives. It is necessary to develop a tool for predicting and preventing trauma. Reducing mortality rate and increasing the Health awareness is the aim. We have used the data mining process, to extract the useful data from large datasets. Feature subset selection is of immense importance in the field of data mining. The increased dimensionality of data makes testing and training of general classification method difficult. Mining on the reduced set of attributes reduces computation time and also helps to make the patterns easier to understand. The CFS approach for feature selection is proposed. As a part of feature selection step we used filter approach algorithm as random search technique for subset generation, wrapped with different classifiers/ induction algorithm namely decision tree C 4.5, Naïve Bayes, as subset evaluating mechanism on standard datasets. It is mandatory to obtain ethical and legal clearance from regional as well as Institutional Ethics Review Board (IERB), before using data mining tools in health care research. We got Ethical clearance from BGS Hospital for using the datasets. These datasets were gathered from the patient files which were recorded in the medical record section of the BGS Hospital Bangalore. Further the relevant attributes identified by proposed filter are validated using classifiers. Experimental results illustrate, employing feature subset selection using proposed filter approach has enhanced classification accuracy. Applying [DM ] techniques to the data brings about very interesting and valuable results. It is concluded that in this case, comparing the result of evaluating the models on test set, decision tree works better than NaiveBayes. In this paper, we have also used WEKA Tool for creating the models. Keywords-CFS, DataMining, Trauma, GCS,CFS
Modeling of spectral response measurements on two-terminal multi-junction solar cells

Accurate measurements on the spectral response of two-terminal multi-junction solar cells demand the application of appropriate bias light and bias voltage. Typically, fine-tuning the bias condition is a time- and effort-consuming process. In this work, a model with realistic input was developed for simulating the spectral response of multi-junction solar cells obtained in certain measurement conditions. As such spectral response can be anticipated in the measurement with the assigned opto-electrical bias configuration, the model expedites the process of finding the optimal bias condition, as well as the understanding of the causes of measurement artifacts. The model can be further extended to simulate the devices made with different PV technologies, so it facilitates the reliable characterization of novel multi-junction architectures.
Loss of membranous E‐cadherin expression in pancreatic cancer: Correlation with lymph node metastasis, high grade, and advanced stage

Epithelial cadherin (E‐cadherin) is a Ca2+‐dependent cell‐cell adhesion molecule that connects cells via homotypic interactions. Its function is critical in the induction and maintenance of cell polarity and differentiation, and its loss of downregulation is associated with an invasive and poorly differentiated phenotype in colon and other tumours. We have used an avidin‐biotin immunoperoxidase technique to localize E‐cadherin in microwave‐treated, paraffin‐embedded sections from 36 patients with pancreatic adenocarcinomas. E‐cadherin was expressed by normal ductal and acinar cells with typical membranous staining at the intercellular junctions. Loss of normal surface E‐cadherin expression was found in 19/36 (53 per cent) tumours compared to the adjacent normal ductal cells. Abnormal E‐cadherin expression was found more frequently in poorly differentiated (grade III) (6/7, 86 per cent) than in well‐differentiated tumours (grade I) (4/14, 28 per cent) (P=0·012). Membranous E‐cadherin expression was also lost more frequently in primary tumours with lymph node (stage III) (14/23, 61 per cent) and distant metastasis (stage IV) (2/2, 100 per cent) compared with 3/11 (27 per cent) lymph node‐negative tumours (stage I) (P=0·043). In conclusions, our data indicate that loss of membranous E‐cadherin expression is associated with high grade and advanced stage in pancreatic cancer.
Impact of human hair configuration on the human head absorption rate

In this paper, electromagnetic cellular propagation modeling with the presence of a human head is presented, taking into account the nature of the human hair existing in the world. Numerical results obtained by the “Complete Technology” approach - offering Finite Integration Technique, Finite Element Method, Method of Moments, MLFMM, Transmission-line matrix and System Assembly and Modeling - are presented in CST Studio Suite simulations. As a cellular network, a typical IEEE human head has been used for this study featuring several ways of implementing hair on it and adding more layers to this hair. A patch directional antenna (also known as a rectangular micro strip antenna) that is resonant at 2.4 GHz is used for simulation. The main purpose of this study is to optimize the configuration of the human hair to get to a minimum SAR on the human body lying inside the tested area. Simulation results would provide a chart describing the best configuration of the human hair within environments which use cellular frequently.
Methanolic extracts of Aloe secundiflora Engl. inhibits in vitro growth of tuberculosis and diarrhea-causing bacteria

Background: The emergence of resistance to antimicrobials by pathogens has reached crisis levels, calling for identification of alternative means to combat diseases. Objective: To determine antimicrobial activity of crude methanolic extract of Aloe secundiflora Engl. from Lake Victoria region of Kenya. Materials and Methods: Extract was tested against four strains of mycobacteria (Mycobacterium tuberculosis, M. kansasii, M. fortuitum and M. smegmatis), Salmonella typhi, Staphylococcus aureus, Pseudomonas aeruginosa, Escherichia coli, Klebsiella pneumoniae and a fungus Candida albicans. activity of the extract was determined using BACTEC™ MGIT™ 960 system. General antibacterial and antifungal activity was determined using standard procedures: zones of inhibition, Minimum Inhibitory Concentrations (MICs) and Minimum Bactericidal/Fungicidal Concentrations (MBCs/MFCs). Results: The extract was potent against M. fortuitum, M. smegmatis and M. kansasii where it completely inhibited growth (Zero growth units (GUs)) in all the extract concentrations used. It gave strong antimycobacterial activity (157 GUs) against M. tuberculosis. It showed strong antimicrobial activity (P≤0.05), giving inhibition zones ≥9.00 mm against most microorganisms, such as P. aeruginosa (MIC 9.375 mg mL-1 and MBC of 18.75 mg mL-1), E. coli (both MIC and MBC of 18.75 mg mL-1), S. aureus and S. typhi (both with MIC and MBC of 37.5 mg mL-1). Preliminary phytochemistry revealed presence of terpenoids, flavonoids and tannins. Conclusion: The data suggests that Aloe secundiflora could be a rich source of antimicrobial agents. The result gives scientific backing to its use by the local people of Lake Victoria region of Kenya, in the management of conditions associated with the tested microorganisms.
Community integration: a useful construct, but what does it really mean?

The primary objective of this paper is to contribute to a clearer understanding of the construct of community integration. Rehabilitation literature is discussed in relation to three measures of community integration: the AIMS Interview, Community Integration Measure and Community Integration Questionnaire. Results of a principal components analysis with varimax rotation indicated that the measures are independent and coherent. Significant correlations were not found between total scores on the three measures and problem behaviour or quality of life. However, analysis of individual items on the scales yielded one significant correlation between the first item on the Community Integration Measure (i.e. sense of belonging) and quality of life. The need for a clear statement in future research regarding the definition of community integration is emphasized, and inclusion of both subjective perceptions and objective indicators of community integration is recommended.
A Phylogenetic Analysis of the Allometry of Diving

The oxygen store/usage hypothesis suggests that larger animals are able to dive for longer and hence deeper because oxygen storage scales isometrically with body mass, whereas oxygen usage scales allometrically with an exponent <1 (typically 0.67–0.75). Previous tests of the allometry of diving tend to reject this hypothesis, but they are based on restricted data sets or invalid statistical analyses (which assume that every species provides independent information). Here we apply information‐theoretic statistical methods that are phylogenetically informed to a large data set on diving variables for birds and mammals to describe the allometry of diving. Body mass is strongly related to all dive variables except dive:pause ratio. We demonstrate that many diving variables covary strongly with body mass and that they have allometric exponents close to 0.33. Thus, our results fail to falsify the oxygen store/usage hypothesis. The allometric relationships for most diving variables are statistically indistinguishable for birds and mammals, but birds tend to dive deeper than mammals of equivalent mass. The allometric relationships for all diving variables except mean dive duration are also statistically indistinguishable for all major taxonomic groups of divers within birds and mammals, with the exception of the procellariiforms, which, strictly speaking, are not true divers.
Moral Reminder as a Way to Improve Worker Performance on Amazon Mechanical Turk

The present study explores a method to reduce abusive worker behavior on Amazon Mechanical Turk (AMT), namely reminding workers of moral standards. We manipulated workers’ awareness of moral standards via the presence or the absence of an honesty statement in a survey. The results showed that the honesty statement significantly improved workers’ performance during the first half of the survey. This suggests that a moral reminder is a simple and efficient way to reduce abusive worker behavior in a relatively short survey on AMT.