Miracle-dz/UniFAR-FTUs huggingface dataset:
Renal Cell Carcinoma Intravascular Spread Into Segmental Branches of the Renal Vein: A Single Institution Case Series

(1) Background: Overall survival of the patients with renal cell carcinoma (RCC) depends mostly on extra-renal extension, documented by the invasion of the pelvicalyceal system, or the perinephric/renal sinus fat or the renal vein/its segmental intraparenchymal branches. Staging may be challenging because of the high inter-observer variability. We have introduced a more accurate procedure to detect the extra-renal extension and, to possibly evaluate the impact of such more laborious approach, we have compared the RCC pathological staging obtained following both standard and modified procedures; (2) Methods: We selected 54 consecutive cases of RCC diagnosed 18 months before and 54 consecutive cases diagnosed 18 months after the introduction of the new method of sampling. Clinico-pathological characteristics have been statistically analyzed; (3) Results: Most of the features analyzed were non statistically significative, except the extra-renal invasion. More precisely, the occurrence of retrograde venous invasion was higher in the cases grossly approached with the more accurate method; (4) Conclusions: Extra-renal extension to intraparenchymal renal vein branches may be underestimated, leading to an inappropriate under-staging. Using more accurate staging procedures, to disclose the occurrence of intra-renal veins tumoral thrombosis, helps to better define the pathological stage, allowing patients to benefit of better fitting treatments.
EFFECT OF LERAK (SAPINDUS RARAK) EXTRACT IN HIGH ROUGHAGE DIET ON RUMEN MICROBIAL PROTEIN SYNTHESIS AND PERFORMANCE OF SHEEP

Secondary compounds containing plant extract as feed additive may improve the performance of livestock consuming high roughage diet. An in vivo trial was conducted to investigate the effect of Sapindus rarak extract (SRE) on ruminal fermentation products, microbial protein synthesis, and growth performance of sheep. Sheep (male, 28 heads) fed high roughage diet were arranged in a completely randomized design with four treatments: addition of SRE to the diet at 0, 4, 8 and 12 g head-1 day-1. The experiment was conducted for 105 days with 2 weeks adaptation period. At the end of the experiment, total faeces was collected for 1 week and rumen liquor was taken. Variables measured were ruminal fermentation products, microbial protein synthesis, daily intake, digestibility, N retention, body weight, and average daily gain. Protozoal numbers were significantly decreased with increasing SRE dose. The ruminal NH3 concentration tended to reduce by SRE addition (P = 0.06). SRE significantly increased propionate and efficiency of microbial protein synthesis from 6.4 to 10.5 g N kg-1 DOMR. SRE significantly improved average daily gain of sheep during the first 70 days of experiment without affecting intake and digestibility. SRE did not alter carcass percentage but tended to lower pancreas and liver weights (P<0.1). In conclusion, SRE has a significant role in partially defaunated rumen microflora, hence, increased microbial protein synthesis and propionate production in the rumen. Addition of SRE is useful to increase daily gain of sheep fed high roughage diet in 70 days of feeding.
In-vitro postantibiotic effect (PAE) of ciprofloxacin against different bacterial species

The PAEs of ciprofloxacin against Salmonella dublin, E. coli, Pasteurella multusida and Staphylococcus aureus were determined. Growth curves of the organisms were constructed with and without addition of antibiotics and the two curves were compared. The longest PAE when it was subjected to an antibiotic (1 mg/ml ciprofloxacin) was observed against Staphylococcus aureus (6 hours) and the shortest was against Pasteurella multocida (1–2 hours), whereas the PAE of 4 hours was found for Salmonella dublin. E. coli was found to be resistant to ciprofloxacin in all phases. Keywords: Ciprofloxacin, PAE, Salmonella dublin, E coli, Pasteurella multusida, Staphylococcus aureus.
A Novel Integrated Technique for Forgery Detection for Copy-Move Forgery

: This paper introduces to image forgery detection by adaptive over segmentation and feature point matching. The proposed method uses both block based and key-point based techniques to detect forgery region. The adaptive over segmentation technique divides the host image or input image into non-overlapping irregular shapes called as image blocks (IB). Then by using the scale invariant feature transform(SIFT)we extract the block features(BF) in each block of the image, following by adaptive block feature matching where the block features of each block are matched or compared with other blocks by this estimated or suspected forgery region can be identified. Then by using forgery region extraction algorithm we convert the labelled feature points are converted into small super pixels and by merging the similar neighbouring feature points and then by using morphological operation we find the forgery region of an image.
Geology of Shantipur-Wami Taksar Areas of Gulmi-Baglung Districts, Western Nepal

The study area represents a small part of the Lesser Himalaya in western Nepal and lies about 346 km west from Kathmandu. It covers 250 km area representing some parts of Gulmi and Baglung districts. The area was selected for the present study on the impression from the previous geological map that has showed some metallic mineral resources like iron, copper and lead in the region. Similarly, studies reveal that there is very complicated geological structure which raised the interest for the study. Main objective of the study was to prepare a geological map of the area in a scale of 1:25,000 and study the possible mineral deposits. An extensive geological mapping was carried out in the field covering at one data within one centimetre of the map scale and large number of samples was collected for the petrographic as well as ore genesis studies. The rocks of the region were mapped under two geological units as the Nourpul Formation (older) and the Dhading Dolomite (younger). There are a series of folds in the area. From regional to micro-scale all folds are trending towards east-west. The Badi Gad Fault and the Harewa Khola Thrust are the regional scale thrust mapped in the area. The Badi Gad is considered as a strike-slip in nature. The Harewa Khola Thrust is probably an imbricate fault. It has propagated to the north which is out of sequence in nature. Some metallic minerals like copper and iron along with old working mines were observed during the study. Occurrences of copper and iron mineralization has been mapped and described. Present study revealed that copper mineralization is limited within the veins and boudinage forms as hydrothermal deposit while the iron is tabular and syngenetic in nature.
Global projections of compound coastal meteorological extremes

Compound coastal and inland flooding can result in catastrophic impacts in densely populated low-lying coastal areas. The dynamics and interactions between the underlying meteorological drivers in view of climate change are not fully understood at global scale. Here, we show that under a high emissions scenario the concurrence probability of extreme meteorological tides and inland precipitation would increase by more than 30% on average along coastlines worldwide by 2100 compared to present. In latitudes above 40o north, compound meteorological extremes would become more than 2.5 times as frequent, while they would happen less frequently in parts of the subtropics. Climate-induced dynamics in precipitation extremes contribute to about 80% of the projected change in concurrence probability, while dynamics in meteorological tides account for 16% and those in the dependence between the two extremes for 4%. Our results indicate that not accounting for these effects in adaptation planning could leave coastal communities insufficiently protected against flooding.
Individual Differences in Conflict Detection, Numeracy, and Processing Preference

Conflict detection is a phenomenon in which an individual detects when there is a difference between an intuitive and a logical response. Few studies have investigated the underlying factors that contribute to conflict detection. Possible factors include a preference and an ability to use numerical information during a judgment task. In the present study, participants estimated subjective probabilities, and completed the Subjective Numeracy Scale and the Fuzzy Processing Preference Index which assess numerical ability and preference for using numerical information respectively. We found no differences between detectors and non-detectors in terms of numeracy or processing preference, suggesting that conflict detection is not influenced by either an ability or tendency to use and understand numerical information.
Comparison between Model Test and Three CFD Studies for a Benchmark Container Ship

An alternative to experiments is the use of numerical model tests, where the performances of ships can be evaluated entirely by computer simulations. In this paper, the free surface viscous flow around a bare hull model is simulated with three Computational Fluid Dynamics (CFD) software packages (FINE Marine, ANSYS CFD and SHIPFLOW) and compared to the results obtained during the experimental tests. The bare hull model studied is the Duisburg Test Case (DTC), developed at the Institute of Ship Technology, Ocean Engineering and Transport Systems (ISMT) for benchmarking and validation of the numerical methods. Hull geometry and model test results of resistance, conducted in the experimental facility at SVA Postdam, Nietzschmann, in 2010, are publicly available. A comparative analysis of the numerical approach and experimental results is performed, related to the numerical simulation of the free surface viscous flow around a typical container ship. Further, a comparative analysis between the results provided by NUMECA, ANSYS and SHIPFLOW is performed. Regarding the solution obtained, a satisfactory agreement between the towing test results and the computation results can be noticed. The minimum mean error was obtained through the SHIPFLOW case, 2.011%, which proved the best solution for the case studied.
Targeted Editing of SlMAPK6 Using CRISPR/Cas9 Technology to Promote the Development of Axillary Buds in Tomato Plants

The mitogen-activated protein kinase (MAPK) cascade signaling system has been relatively conserved throughout the evolution of eukaryotes and is involved in the regulation of growth and development and metabolism. In this study, dwarf tomato plants were used as the research material. First, the tissue-specific expression of SlMAPK6 was measured in wild-type plants by quantitative RT-PCR. The results showed that SlMAPK6 was highly expressed in the tissues of the stems, leaves and flowers but was expressed at low levels in the tissues of the roots, sepals and fruits. Second, SlMAPK6-knockout lines CRISPR-3 and CRISPR-7 were obtained by CRISPR-Cas9 technology and Agrobacterium-mediated transformation. Compared with wild-type, the mutant lines CRISPR-3 and CRISPR-7 showed significant phenotypic characteristics, such as increased numbers of axillary buds and true leaves, thickened stems, and longer leaflets. In addition, to explore the molecular mechanism by which MAPK regulates axillary bud growth, we also showed that SlMAPK6 positively regulates the strigolactone synthesis genes SlCCD7 and SlCCD8 and the gibberellin (GA) synthesis genes GA20ox3 and GA3ox1 and negatively regulates the axillary bud development-related genes Ls, BL and BRC1b/TCP8 and the GA synthesis inhibitory gene GAI. Therefore, SlMAPK6 appears to regulate the synthesis of strigolactone and GA to induce the growth and development of tomato axillary buds.
Analysis on predictive effect and accuracy of HPVL1 protein and human papilloma virus dna load in cervical lesions

Objective: We aimed to discuss the predictive effect and accuracy of HPVPL1 protein and human papilloma virus (HPV) DNA load in patients with cervical lesions. Methods: A total of, 103 patients with cervical lesions in our hospital were selected as subjects of study and included in an observation group (OG) and 24 patients with chronic inflammation (CI) and healthy physical examination who received treatment in the same period were included in the control group (CG). A definite diagnosis was made in all patients through histocytological examination. The HC2 technology was used for the measurement of HPV DNA load in patients; and immunohistochemistry (IHC) was used for the measurement of HPVPL1 protein in cervical exfoliated cells (CEC) in the two groups. The histocytological diagnosis results were taken as the gold standard to compare the predictive effect of HPVPL1 protein and HPV DNA load in cervical diseases. Results: A definite diagnosis of cervical lesions was made in 127 patients through histocytological examination. Thereinto, there were 103 patients with cervical lesions, including 27 with CIN1, 32 with CIN2 and 24 with CIN3. There were 24 patients with CI in the CG. The negative rate (NR) of HPV DNA load in the OG was lower than that in the CG (P<0.05). There were statistical differences in NR of CIN Stage I, CIN Stage II, CIN Stage III and HPV DNA load in cervical cancer (CC) in the OG (P<0.05). The positive rate (PR) of HPVPL1 protein in CEC in the OG was higher than that in the CG (P<0.05). The sensitivity and specificity of HPVPL1 combined with HPV DNA load in cervical lesions were higher than those of single HPVPL1 or HPV DNA load (P<0.05). Conclusion: The expression of HPVPL1 protein in CEC showed a descending trend in patients with cervical lesions while the HPV DNA load showed a rising trend, so the joint detection through the two methods could predict cervical diseases and is worthy of promotion and application.
Supplementary for “SegFix: Model-Agnostic Boundary Reﬁnement for Segmentation”

mean 1 1.0 4.2 2.7 4.4 4.3 20.1 12.2 9.0 2.8 5.2 3.5 8.1 10.9 2.5 2.2 2.4 3.2 8.4 8.3 2.6 2 1.9 8.2 5.2 8.5 8.3 38.1 23.4 17.5 5.6 10.1 6.8 15.8 21.0 4.9 4.4 4.7 6.2 16.3 16.0 5.2 3 2.7 11.4 7.2 12.0 11.7 51.6 32.3 24.2 7.8 14.0 9.5 21.6 28.2 6.8 6.2 6.7 8.6 21.9 21.4 7.2 4 3.5 14.5 9.2 15.3 14.9 61.8 40.3 30.5 9.9 17.7 12.0 26.9 34.8 8.7 7.9 8.5 10.9 27.1 26.5 9.1 5 4.4 18.0 11.4 18.8 18.2 69.8 48.5 37.1 12.4 21.7 15.0 33.4 42.6 11.0 9.8 10.7 13.6 33.2 32.4 11.2
Unsaturated carbohydrates. Part IV. Allylic rearrangement reactions of 3,4,6-tri-O-acetyl-D-galactal

Reaction of tri-O-acetyl-D-galactal with alcohols and phenols is shown to give glycoside derivatives containing a 2,3-double bond. In boiling acetic acid the glycal acetate undergoes competing addition and rearrangement reactions, and ultimately gives a diene which is assigned a pyranoid structure; crystalline 1,3,4,6-tetra-O-acetyl-2-deoxy-α-D-lyxo-hexose, 3,4,6-tri-O-acetyl-D-gulal, and 1,4,6-tri-O-acetyl-2,3-didehydro-2,3-dideoxy-α-D-threo-hexose have been isolated. The same products can be obtained by heating the saturated acetate in acetic acid. In the presence of added methanesulphonic acid, only minor amounts of unsaturated compounds are formed from the glycal ester.The product of alkaline degradation of 2-deoxy-D-lyxo-hexose has been studied briefly.
Molecular characterization of Indian species of the genus Cornudiscoides Kulkarni, 1969 (Monogenoidea: Dactylogyridae)

Molecular characterization and phylogenetic study based on partial sequences of 28S and 18S ribosomal DNA (rDNA) of sixteen Indian species of the genus Cornudiscoides (Monogenoidea: Dactylogyridae) were conducted to decode the genetic relationship between them and with other members of the family Dactylogyridae. Blastn searches disclosed the significant similarity among the species of the Cornudiscoides for large ribosomal subunits as well as for small ribosomal subunit showing genetic relatedness. The phylogenetic tree using neighbour-joining (NJ) and minimum evolution (ME) methods for 28S ribosomal subunit depicted that all Cornudiscoides species clustering in a single clade and forming sister clade with other members of the family Dactylogyridae and similar results were obtained from 18S ribosomal subunit. Thus, the present study demonstrated that both 28S and 18S ribosomal subunits are very helpful in discriminating Cornudiscoides species (intra or interspecific variation) and in the establishment of the evolutionary relationship among them.
High-resolution numerical schemes for hyperbolic conservation laws, and their performance on modern HPC architectures

In this paper, we derive a new second-order fully discrete Godunov-type centralupwind scheme for two-dimensional hyperbolic systems of conservation laws. The scheme is derived in three steps: reconstruction, evolution, and projection. The novelty of our approach is in the evolution step, which is performed using the nonuniform quadrilateral control volumes obtained based on the one-sided local speeds of propagation, and in the projection step, in which the evolved solution is projected back onto the uniform grid with the help of a new sharp piecewise polynomial reconstruction. The scheme is tested on a number of numerical examples for the Euler equations of gas dynamics. We have demonstrated that the new scheme is nonoscillatory and at the same time it achieves higher resolution than the second-order semidiscrete central-upwind scheme. The latter suggests that the fully discrete scheme has a smaller amount of numerical dissipation.
ACCURACY AND PRECISION OF SMARTPHONES IN MEASUREMENTS OF ILLUMINANCE AND LIQUID TURBIDITY

Smartphones have demonstrated being attractive tools for illuminance and liquid turbidity measurements. The ambient light sensor and its corresponding mobile application can measure the reduction in illuminance with the distance away from a light source. The indirect measurement of turbidity is performed via the light passing through a solution. The illuminance linearly decreases with the increase in molar concentration of solution and a linear conversion equation to the turbidity can be obtained. By repeating the experiment, the uncertainty in direct measurements of illuminance is less than 1 %, ensuring an appropriate precision for educational and professional uses. Los teléfonos inteligentes han demostrado ser herramientas atractivas para las mediciones de iluminación y turbidez. El sensor de luz ambiental y su aplicación para móvil son capaces de medir la reducción en la iluminación con la distancia desde la fuente de luz. La medición indirecta de la turbidez se hace mediante la luz a través de la solución. La iluminación decrece linealmente con el incremento en la concentración molar de una solución, de modo que se puede obtener una ecuación de conversión lineal a la turbidez. Repitiendo el experimento, la incertidumbre en mediciones de iluminación es menor que el 1 %, lo que asegura una precisión suficiente para usos educacionales y profesionales.
An extended macroeconomic model of the Hungarian economy

Hungary was one of the most promising countries in the Eastern European area after the regime change in 1989. As a post-communist country that was already making approaches to western economies and introduced normative regulations since 1968 [24], it had one of the best preconditions in its peer group to make a smooth transition into a market economy and not to leave too big of a gap to the western Europe. Despite the seemingly promising preconditions, Hungary fell into a recession in the early 1990s [20]. The country had to fight a rising national debt, high inflation and a growing unemployment rate that still persists. This thesis elaborates the theoretical aspects for a general understanding of macroeconomic models and discusses the various aspects of a critical economic policy. To estimate the key indicators of the Hungarian economy, a macroeconomic model is used that describes the monetary flows between agents in a closed economy. The adapted model is analyzed and discussed and a dynamic simulation is run to forecast the macroeconomic key indicators for the next five years.
Rapport d’avancement du projet E-horizon sur la thèse #20 ”Vers des réseaux véhiculaires programmables via la technologie SDN”

HAL is a multi-disciplinary open access archive for the deposit and dissemination of scientific research documents, whether they are published or not. The documents may come from teaching and research institutions in France or abroad, or from public or private research centers. L’archive ouverte pluridisciplinaire HAL, est destinée au dépôt et à la diffusion de documents scientifiques de niveau recherche, publiés ou non, émanant des établissements d’enseignement et de recherche français ou étrangers, des laboratoires publics ou privés. Rapport d’avancement du projet E-horizon sur la thèse #20 ”Vers des réseaux véhiculaires programmables via la technologie SDN” Soufian Toufga, Slim Abdellatif, Philippe Owezarski, Thierry Villemur
Theory of DNA electrophoresis (∼ 1999 –2002 ½)

Over the last two decades, the introduction of new methods such as pulsed‐field gel electrophoresis and capillary array electrophoresis has made it possible to map and sequence entire genomes, including our own. The development of these experimental methods has been helped by the progress of theoretical and computational sciences, and the interactions between these three modi operandi of modern science are still pushing the limits of our technologies. We now see a clear trend towards proteomics and microfluidic (even nanofluidic! ) devices. In this review, we take a look at the progress of the field over the last 3 years using the glasses of the theoretical scientist and focusing mostly on new ideas and concepts. About a dozen different subfields are discussed and reviewed. We conclude by giving a commented list of some of the best review articles published over the last 2–3 years.
ENHANCED DUCKWEED ALKALI TOLERANCE BY OVERSPRESSION OF SERINE: GLYOXYLATE AMINOTRANSFRASE (ATAGT1)

Alkaline salts are more harmful to plants than neutral salts. Improvement on the alkaline tolerance in plants is important to make full use of the large area of saline-alkaline water. It has been proved that photorespiration pathway provides protection to plants under stress. In this study, Arabidopsis serine: glyoxylate aminotransferase (AtAGT1)transgenic duckweeds were studied to investigate the alkaline stress tolerance. Enhanced protection from damage to cell membrane was detected in transgenic duckweeds under Na2CO3 treatment. Also, in the transgenic duckweed, reactive oxygen species (ROS) accumulation was decreased, and antioxidant enzyme activities were improved with alkaline condition. These results indicated that with the enhancement of photorespiration, antioxidant enzyme activities were improved, leading to the decline of ROS content under alkaline stress. These results also revealed the function of photorespiration enzyme during alkaline stress.