Miracle-dz/UniFAR-FTUs huggingface dataset:
Dietary Supplementation With Hydroxyproline Enhances Growth Performance, Collagen Synthesis and Muscle Quality of Carassius auratus Triploid

An eight-week experiment was undertaken to examine the effect of dietary hydroxyproline (Hyp) supplementation on growth performance, collagen synthesis, muscle quality of an improved triploid crucian carp (Carassius auratus Triploid) (ITCC). Six isonitrogenous (340 g/kg diet), isolipidic (60 g/kg diet) and isocaloric (17.80 MJ/kg diet) diets were formulated containing a certain amount of Hyp: 0.09% (the control group), 0.39, 0.76, 1.14, 1.53 and 1.90%. Each diet was randomly assigned to three tanks and each group was fed two times daily until apparent satiation. The results showed that growth performance and feed utilization of ITCC were significantly improved with the dietary Hyp level was increased from 0.09 to 0.76%. Crude protein, threonine and arginine content in the dorsal muscle in 0.76% hydroxyproline group were significantly higher than those in basic diet group (p < 0.05). The muscle textural characteristics increased remarkably with the amount of Hyp in the diet rising from 0.09 to 1.53% (p < 0.05). Meanwhile, the contents of type I collagen (Col I) and Pyridinium crosslink (PYD) in the muscle of fish were significantly increased by dietary Hyp (p < 0.05). The muscle fiber diameter and density of the fish were significantly increased when fed with 0.76% Hyp (p < 0.05). Furthermore, dietary supplementation with an appropriate concentration of Hyp substantially increased the expression of genes involved in collagen synthesis (col1a1, col1a2, p4hα1, p4hβ, smad4, smad5, smad9, and tgf-β) and muscle growth (igf-1, tor, myod, myf5, and myhc) (p < 0.05). In conclusion, dietary supplementation of Hyp can enhance fish growth performance, collagen production, muscle textural characteristics and muscle growth of ITCC. According to the SGR broken-line analysis, the recommended supplementation level of Hyp was 0.74% in the diet for ITCC, corresponding to 2.2% of dietary protein.
A Systematic Review and Meta-Analysis on the Accuracy of Fluorodeoxyglucose Positron Emission Tomography/ Computerized Tomography for Diagnosing Periprosthetic Joint Infections

Objective Fluorodeoxyglucose Positron emission tomography/computerized tomography (FDG PET/CT) has become popular for diagnosing periprosthetic joint infections (PJI). However, the diagnostic accuracy for this technique has varied from report to report. This meta-analysis was performed to assess the accuracy of FDG PET/CT for PJI diagnosis. Material and Methods We conducted a systematic search of online academic databases for all studies reporting the diagnostic accuracy of FDG PET/CT for PJI. Meta-analysis was performed using STATA software. Results 23 studies, containing data on 1,437 patients, met inclusion criteria. Pooled sensitivity and specificity of FDG PET/CT for diagnosing PJI were 85% (95% CI, 76%, 91%) and 86% (95% CI, 78%, 91%), respectively with an AUC of 0.92. LRP was 6.1 (95% CI, 3.8, 9.7) and LRN was 0.17 (0.11, 0.28), indicating that FDG PET/CT cannot be used for confirmation or exclusion of PJI. There was significant inter-study heterogeneity, but no significant publication bias was noted. Conclusions Our study found that FDG PET/CT has an important role as a diagnostic tool for PJI with high sensitivity and specificity. Further studies exploring its accuracy in different PJI locations remain necessary.
Differences in Fatty Acids and Lipids of Massive and Branching Reef-Building Corals and Response to Environmental Changes

Reef-building corals present various colony morphologies that may greatly influence their nutritional ecology. Fatty acids (FAs) and lipids are important components of corals and have been increasingly used to research the nutritional ecology of corals. In this study, we examined the symbiodiniaceae density, corallite area, total lipid content, and FAs composition of 14 species of corals with different colony morphologies. The results showed that the different colony morphology of coral was significantly correlated with the corallite area but not with the symbiodiniaceae density. Massive corals, with a large corallite area (7.16 ± 6.29 mm2), could ingest a high quantity of food, leading to high levels of total lipid content and unsaturated FAs [particularly n-6 polyunsaturated FAs (PUFAs) and monounsaturated FAs]. For branching corals, the total lipid content and saturated FAs (SFAs, 16:0 and 18:0) were significantly positively correlated with the Symbiodiniaceae density, indicating that branching corals are predominantly autotrophic. Moreover, compared with healthy corals, bleached corals consume larger amounts of stored energy (such as lipids and SFAs) to maintain their normal physiological functions. Although bleached corals may obtain PUFAs from heterotrophic assimilation or biosynthesize, the efficiency is too low to sufficiently replenish essential PUFAs in a short time. Overall, massive corals with more initial total lipid content and PUFAs exhibit an advantage under adverse environmental conditions.
Sketching the Landscape of Speech Perception Research (2000–2020): A Bibliometric Study

Based on 6,407 speech perception research articles published between 2000 and 2020, a bibliometric analysis was conducted to identify leading countries, research institutes, researchers, research collaboration networks, high impact research articles, central research themes and trends in speech perception research. Analysis of highly cited articles and researchers indicated three foundational theoretical approaches to speech perception, that is the motor theory, the direct realism and the computational approach as well as four non-native speech perception models, that is the Speech Learning Model, the Perceptual Assimilation Model, the Native Language Magnet model, and the Second Language Linguistic Perception model. Citation networks, term frequency analysis and co-word networks revealed several central research topics: audio-visual speech perception, spoken word recognition, bilingual and infant/child speech perception and learning. Two directions for future research were also identified: (1) speech perception by clinical populations, such as hearing loss children with cochlear implants and speech perception across lifespan, including infants and aged population; (2) application of neurocognitive techniques in investigating activation of different brain regions during speech perception. Our bibliometric analysis can facilitate research advancements and future collaborations among linguists, psychologists and brain scientists by offering a bird view of this interdisciplinary field.
Prevalence and Related Factors of Anxiety Among University Teachers 1 Year After the COVID-19 Pandemic Outbreak in China: A Multicenter Study

Objectives This study aimed to evaluate the prevalence of anxiety among university teachers 1 year after the onset of the coronavirus disease 2019 (COVID-19) pandemic and provide empirical evidence of psychological intervention. Methods A multicenter study was conducted to examine the prevalence of anxiety among 10,302 teachers in 21 Chinese universities from February 12 to April 23, 2021. The generalized Anxiety Disorder 7-item Scale (GAD-7) was used to assess symptoms of anxiety. Multivariate logistic regression models were used to analyze the relationship between potential influence and anxiety symptoms. Results The overall prevalence of anxiety was 40.0% 1 year after the onset of the COVID-19 pandemic, which was found to be higher in women than in men (41.32% vs. 38.22%; p < 0.0001). The multivariate logistic regression showed that being the female (OR = 1.207; 95%CI: 1.103–1.318), age ≥60 years (OR = 2.004; 95%CI: 1.128–3.560), being married (OR = 1.319; 95%CI: 1.150–1.513), and poor family economic status (OR = 1.580; 95%CI: 1.321–1.891) were significantly associated with anxiety. Participants with moderate, slight, or no impact of COVID-19 on life (OR for moderate, 0.557; 95%CI, 0.508–0.611; OR for slight/no, 0.377; 95%CI, 0.323–0.439) showed a reduced risk of anxiety compared to those who reported a significant effect. Conclusions Symptoms of anxiety were found in about two-fifths of Chinese university teachers 1 year after the outbreak of the COVID-19 pandemic. Our findings suggest that the government should improve the dynamic tracking of mental health and adopt long-term intervention strategies.
Gait and Neuromuscular Changes Are Evident in Some Masters Club Level Runners 24-h After Interval Training Run

Purpose To examine the time course of recovery for gait and neuromuscular function immediately after and 24-h post interval training. In addition, this study compared the impact of different statistical approaches on detecting changes. Methods Twenty (10F, 10M) healthy, recreational club runners performed a high-intensity interval training (HIIT) session consisting of six repetitions of 800 m. A 6-min medium intensity run was performed pre, post, and 24-h post HIIT to assess hip and knee kinematics and coordination variability. Voluntary activation and twitch force of the quadriceps, along with maximum isometric force were examined pre, post, and 24-h post significance HIIT. The time course of changes were examined using two different statistical approaches: traditional null hypothesis significance tests and “real” changes using minimum detectable change. Results Immediately following the run, there were significant (P < 0.05) increases in the hip frontal kinematics and coordination variability. The runners also experienced a loss of muscular strength and neuromuscular function immediately post HIIT (P < 0.05). Individual assessment, however, showed that not all runners experienced fatigue effects immediately post HIIT. Null hypothesis significance testing revealed a lack of recovery in hip frontal kinematics, coordination variability, muscle strength, and neuromuscular function at 24-h post, however, the use of minimum detectable change suggested that most runners had recovered. Conclusion High intensity interval training resulted in altered running kinematics along with central and peripheral decrements in neuromuscular function. Most runners had recovered within 24-h, although a minority still exhibited signs of fatigue. The runners that were not able to recover prior to their run at 24-h were identified to be at an increased risk of running-related injury.
Increased Magnetic Susceptibility in the Deep Gray Matter Nuclei of Wilson's Disease: Have We Been Ignoring Atrophy?

Background Histopathological studies in Wilson's disease (WD) have revealed increased copper and iron concentrations in the deep gray matter nuclei. However, the commonly used mean bulk susceptibility only reflects the regional metal concentration rather than the total metal content, and regional atrophy may affect the assessment of mean bulk susceptibility. Our study aimed to quantitatively assess the changes of metal concentration and total metal content in deep gray matter nuclei by quantitative susceptibility mapping to distinguish patients with neurological and hepatic WD from healthy controls. Methods Quantitative susceptibility maps were obtained from 20 patients with neurological WD, 10 patients with hepatic WD, and 25 healthy controls on a 3T magnetic resonance imaging system. Mean bulk susceptibility, volumes, and total susceptibility of deep gray matter nuclei in different groups were compared using a linear regression model. The area under the curve (AUC) was calculated by receiver characteristic curve to analyze the diagnostic capability of mean bulk susceptibility and total susceptibility. Results Mean bulk susceptibility and total susceptibility of multiple deep gray matter nuclei in patients with WD were higher than those in healthy controls. Compared with patients with hepatic WD, patients with neurological WD had higher mean bulk susceptibility but similar total susceptibility in the head of the caudate nuclei, globus pallidus, and putamen. Mean bulk susceptibility of putamen demonstrated the best diagnostic capability for patients with neurological WD, the AUC was 1, and the sensitivity and specificity were all equal to 1. Total susceptibility of pontine tegmentum was most significant for the diagnosis of patients with hepatic WD, the AUC was 0.848, and the sensitivity and specificity were 0.7 and 0.96, respectively. Conclusion Brain atrophy may affect the assessment of mean bulk susceptibility in the deep gray matter nuclei of patients with WD, and total susceptibility should be an additional metric for total metal content assessment. Mean bulk susceptibility and total susceptibility of deep gray matter nuclei may be helpful for the early diagnosis of WD.
Identifying Topics and Evolutionary Trends of Literature on Brain Metastases Using Latent Dirichlet Allocation

Research on brain metastases kept innovating. We aimed to illustrate what topics the research focused on and how it varied in different periods of all the studies on brain metastases with topic modelling. We used the latent Dirichlet allocation model to analyse the titles and abstracts of 50,176 articles on brain metastases retrieved from Web of Science, Embase and MEDLINE. We further stratified the articles to find out the topic trends of different periods. Our study identified that a rising number of studies on brain metastases were published in recent decades at a higher rate than all cancer articles. Overall, the major themes focused on treatment and histopathology. Radiotherapy took over the first and third places in the top 20 topics. Since the 2010’s, increasing attention concerned about gene mutations. Targeted therapy was a popular topic of brain metastases research after 2020.
Stressed Mothers Receiving Infant Mental Health-Based Early Head Start Increase in Mind-Mindedness

Maternal mind-mindedness is a characteristic of supportive parenting and contributes to many positive social–emotional outcomes in early childhood. However, there is limited knowledge of mind-mindedness among parents experiencing parenting stress from low-income settings. This is a critical gap in evidence given the robust role of supportive parenting in children’s development and the capacity of home-based interventions to improve children’s outcomes through enhancing supportive parenting. This study examined: (1) maternal mind-mindedness, operationalized as mothers’ appropriate mind-related comments (MRC), across toddlerhood in mothers of toddlers who participated in infant mental health (IMH) based Early Head Start (EHS) services; and (2) whether parenting stress moderated EHS program effects on appropriate MRC over time. Data from a primarily White midwestern site in the United States were collected at study enrollment and when toddlers were 14-, 24-, and 36-months of age (N = 152; mothers Mage = 22.4 years, SD = 5.1; toddlers Mage = 14.4 months, SD = 1.3; 51% females). Data included parent-completed questionnaires and observed parent–child interactions, which were coded for MRC. Although there were no main effects of EHS programming on mothers’ appropriate MRC over time, multilevel growth curve modeling indicated that parenting stress moderated EHS effects on mothers’ appropriate MRC over time. Among mothers with greater parenting stress, those who received IMH-based EHS services demonstrated greater proportions of MRC over time as compared to mothers with greater stress in the control group. IMH-based parenting interventions that target parenting stress may promote appropriate MRC in low-income populations during toddlerhood.
What Promotes the Happiness of Vacationers? A Focus on Vacation Experiences for Japanese People During Winter Vacation

Several studies on tourism have examined the effects of vacation and travel on individuals' wellbeing. However, relatively little is known about the underlying psychological factors and mechanisms. Therefore, this study aimed to investigate the effects of a winter vacation on individuals' wellbeing. A total of 507 participants (255 men and 252 women) completed three questionnaires at three different time points. The questionnaires comprised psychological scales and items to seek demographic information so that the changes in their wellbeing could be assessed. The results revealed that people who traveled had higher subjective wellbeing than those who did not. Moreover, out of the four elements of the recovery experience, mastery was the only one influenced subsequent subjective wellbeing. The findings suggest that it is crucial to take vacations and to savor recovery experiences while off work. In particular, experiencing new and challenging events during a vacation was the most significant predictor of vacationers' subsequent wellbeing. Our results clarify what type of vacation is most effective for wellbeing. The results can help tourism practitioners manage their customers' experiences better during their vacations, and these efforts will arguably contribute not only to the wellbeing of vacationers but also to future company growth.
Rapeseed (Brassica napus) Mitogen-Activated Protein Kinase 1 Enhances Shading Tolerance by Regulating the Photosynthesis Capability of Photosystem II

Rapeseed (Brassica napus) is the third-largest source of vegetable oil in the world with an edible, medicinal, and ornamental value. However, insufficient light or high planting density directly affects its growth, development, yield, and quality. Mitogen-activated protein kinases (MAPKs) are serine/threonine protein kinases that play key roles in regulating the responses to biotic and abiotic stresses in plants. In this study, we found that the promoter of BnaMAPK1 contained several light-responsive elements (including the AT1-motif, G-Box, and TCT-motif), consistent with its shading stress-induced upregulation. Compared with the wild type under shading stress, BnaMAPK1-overexpressing plants showed higher light capture efficiency and carbon assimilation capacity, enhancing their shading tolerance. Using RNA sequencing, we systematically investigated the function of BnaMAPK1 in shading stress on photosynthetic structure, Calvin cycle, and light-driven electron transport. Notably, numerous genes encoding light-harvesting chlorophyll a/b-binding proteins (BnaLHCBs) in photosystem II-light-harvesting complex (LHC) II supercomplex were significantly downregulated in the BnaMAPK1-overexpressing lines relative to the wild type under shading stress. Combining RNA sequencing and yeast library screening, a candidate interaction partner of BnaMAPK1 regulating in shading stress, BnaLHCB3, was obtained. Moreover, yeast two-hybrid and split-luciferase complementation assays confirmed the physical interaction relationship between BnaLHCB3 and BnaMAPK1, suggesting that BnaMAPK1 may involve in stabilizing the photosystem II–LHC II supercomplex. Taken together, our results demonstrate that BnaMAPK1 positively regulates photosynthesis capability to respond to shading stress in rapeseed, possibly by controlling antenna proteins complex in photosystem II, and could provide valuable information for further breeding for rapeseed stress tolerance.
Decoupling Using Diamond-shaped Patterned Ground Resonator for Small MIMO Antennas

A decoupling technique using a patterned ground structure for small multiple-input multiple-output (MIMO) antennas is proposed in this study. The MIMO antenna consists of two symmetrical L-shaped inverted-F antenna (IFA) elements designed to operate in the wireless-local-area-network band and installed on a compact printed-circuit board (PCB) with a size of 72.4 × 20 mm2 serving as ground. The two IFA elements have a very short separating distance of only 16.2 mm (0.13λ). To reduce strong mutual coupling, a diamond-shaped patterned ground resonator (DSPGR) with a compact size of 16.2 × 10.13 mm2 is printed on the PCB between the two IFA elements. The effect of the DSPGR on reducing mutual coupling is studied using computer simulation. The impedance bandwidth, mutual coupling, peak gain, radiation pattern and efficiency, envelope-correlation coefficient and multiplexing efficiency of the MIMO antenna are studied using simulation and measurement. Results show that the DSPGR can dramatically reduce mutual coupling between the two IFA elements to below −20 dB within the operating frequency range of 2.18–2.65 GHz (19.5%).
Design, Validation, and Economic Behavior of a Three-Phase Interleaved Step-Up DC–DC Converter for Electric Vehicle Application

Due to the increasing number of direct current (DC) loads in electric vehicles (EVs), DC–DC converters are widely used in EV applications. Hence, a DC distribution system with DC–DC converters is more efficient. A three-phase interleaved step-up DC–DC converter (ISC) has been proposed for use in electric vehicles. Other uses of the proposed ISC converter include aircraft, satellites, industrial, and traction drives. The proposed converter is subjected to a thorough frequency response study, which is explained in detail. The design technique recommends the proper quantity of switches to be used in the system. The reduction in the number of switches results in a 94% increase in the efficiency of this converter. The economic aspects of ISC, such as cost analysis and its procedure, have been discussed. Design models were checked using MATLAB/Simulink, which was interfaced with the real-time simulator OPAL-RT (OP5700) to ensure that they were appropriate. The results have been presented in detail.
In the Pursuit of Synchrony: Northward Shifts in Western Spruce Budworm Outbreaks in a Warming Environment

Outbreaks of western spruce budworm (Choristoneura freemani Freeman) in Douglas-fir [Pseudotsuga menziesii (Mirb.) Franco] forests of western Canada have shifted northward in recent decades. Using forest health survey data collected during the previous century (1909 to 2011) to assess the pattern of range shifts, we found that outbreaks have rapidly shifted to higher latitudes and elevations while gradually retracting from the southern and western portions of its range. Given that the survival of western spruce budworm is affected by access to developing buds, we tested the prediction that this shift was associated with climate change-induced alterations in synchrony between budworm larval emergence and Douglas-fir bud development. We simulated the dates of larval emergence and host budburst annually from 1901 to 2011 using existing phenology models and long-term weather data. Over the last century, the timing of larval emergence in relation to budburst has converged toward optimal synchrony at higher latitudes and elevations, while diverging at lower latitudes and elevations. Shifting synchrony arises from differential responses to temperature by the insect and its host tree; both are reliant upon degree day accumulation, but Douglas-fir bud development is putatively dependent upon an additional photoperiodic threshold. Thus, the potential for warming to cause directional shifts in phenological matching between early season folivores and their host trees may be contingent upon the degree to which each depends on different components of their environments for their development.