Miracle-dz/UniFAR-FTUs huggingface dataset:
Dynamics of host immune response development during Schistosoma mansoni infection

Schistosomiasis is a disease of global significance, with severity and pathology directly related to how the host responds to infection. The immunological narrative of schistosomiasis has been constructed through decades of study, with researchers often focussing on isolated time points, cell types and tissue sites of interest. However, the field currently lacks a comprehensive and up-to-date understanding of the immune trajectory of schistosomiasis over infection and across multiple tissue sites. We have defined schistosome-elicited immune responses at several distinct stages of the parasite lifecycle, in three tissue sites affected by infection: the liver, spleen, and mesenteric lymph nodes. Additionally, by performing RNA-seq on the livers of schistosome infected mice, we have generated novel transcriptomic insight into the development of schistosome-associated liver pathology and fibrosis across the breadth of infection. Through depletion of CD11c+ cells during peak stages of schistosome-driven inflammation, we have revealed a critical role for CD11c+ cells in the co-ordination and regulation of Th2 inflammation during infection. Our data provide an updated and high-resolution account of how host immune responses evolve over the course of murine schistosomiasis, underscoring the significance of CD11c+ cells in dictating host immunopathology against this important helminth infection.
From Xizang to Xinjiang: An Analysis of the Role of Diaspora-Based Transnational Social Movements in Opposing Chinese Ethnic Minority Treatment

During the last few decades, the world has seen a significant rise in China’s international clout and, consequently, key international powers and actors have shifted their approach in engaging with the Asian giant, particularly regarding issues that China itself presents as internal or pertaining to national sovereignty. This article pursues an inquiry into the relationship between one such issue, Chinese ethnic minority treatment, and another recent shift in international context: the increased relevance of international forces and pressures originated by transnational social movements founded by ethnic minority members who have chosen to leave China. In order to do so, the diasporas of two ethnic minorities will be studied: the Tibetan minority residing in the Xizang Autonomous Region and the Uyghur minority in the Xinjiang Uyghur Autonomous Region of China. This includes a study of the forms of international resistance in which diaspora members are involved, as well as of the ability of diaspora-based transnational social movements to influence public opinion, state policies, and international organization positions in favor of their ethnic group.
The Effects of Short-Duration High-Intensity Soccer Fatigue Simulation on Dynamic Balance and Lower Limb Isokinetic Strength in Youth Soccer Players

Background. This study investigated the effects of short-duration high-intensity simulation of soccer fatigue on the dynamic balance and isokinetic strength of the lower limbs in youth soccer players. Methods. Thirty-nine youth soccer players completed a high-intensity fatigue simulation in 5-min. The participants performed tests on dynamic balance and isokinetic strength before the fatigue simulation (PRE), immediately after simulation (POST5), and 20 min (POST20) and 35 min (POST35) after simulation. Dynamic balance was measured using the Y-Balance test for both legs in the anterior, posteromedial (PM), and posterolateral (PL) directions. The muscle strength of the lower limb was measured using the maximal isokinetic contraction of the dominant leg only. Results. Dynamic balance was significantly reduced after stimulation in all directions for both legs (P<0.005). Significant reduction in the eccentric hamstring, concentric hamstring, and concentric quadriceps peak torques were also observed (P<0.05). However, no significant reductions were found in the functional hamstring/quadriceps ratio and conventional hamstring/quadriceps ratio (P>0.05). Conclusion. Fatigue influences dynamic balance, hamstrings, and quadriceps strength which may have implications for higher risk of knee injury in youth players.
Transcriptomic Insight into Viviparous Growth in Water Lily

Water lily is an important ornamental flower plant which is capable of viviparous plantlet development. But no study has been reported on the molecular basis of viviparity in water lily. Hence, we performed a comparative transcriptome study between viviparous water lily Nymphaea micrantha and a nonviviparous species Nymphaea colorata at four developmental stages. The higher expression of highly conserved AUX/IAA, ARF, GH3, and SAUR gene families in N. micrantha compared to N. colorata is predicted to have a major impact on the development and evolution of viviparity in water lily. Likewise, differential regulation of hormone signaling, brassinosteroid, photosynthesis, and energy-related pathways in the two species provide clues of their involvement in viviparity phenomenon. This study revealed the complex mechanism of viviparity trait in water lily. The transcriptomic signatures identified are important basis for future breeding and research of viviparity in water lily and other plant species.
Further results on stability analysis of Takagi–Sugeno fuzzy time-delay systems via improved Lyapunov–Krasovskii functional

The problem of delay-range-dependent (DRD) stability analysis for continuous time Takagi–Sugeno (T–S) fuzzy time-delay systems (TDSs) is addressed in this paper. An improved DRD stability criterion is proposed in an linear matrix inequality (LMI) framework by constructing an appropriate delay-product-type (DPT) Lyapunov–Krasovskii functional (LKF) to make use of Bessel-Legendre polynomial based relaxed integral inequality. The modification in the proposed LKF along with the judicious choice of integral inequalities helps to obtain a less conservative delay upper bound for a given lower bound. The efficacy of the obtained stability conditions is validated through the solution of three numerical examples.
Continuous damage approach in analysis of concrete structures under impulsive load

This study analyzes the highly nonlinear shock-wave phenomena in reinforced concrete plates blast loaded by contact detonation of a explosive charge. The response of reinforced concrete to such dynamic loads is of great interest for designing safety facilities. In order to obtain reliable results from numerical analysis, an improved material model for concrete was adopted and implemented into a finite element code. The first part of the paper focuses on the description of the material model, and the second part is devoted to the validation of the assumed model by the numerical simulation of an experimental test, performed by Kraus and Roetzer [6].
Design of Multi-Agent Pathfinding Robot Using Improved Flood Fill Algorithm in Maze Exploration

—Maze exploration is a field of science that continues to be researched and developed. Various algorithms, techniques, and scenarios result in faster trips and shortest distances. Various international competitions in the maze field are also held to encourage quicker and better labyrinth exploration innovations. Usually, maze exploration uses a mobile robot that moves autonomously in pathfinding to reach the target location. This study aims to generate and test a multi-agent algorithm to find the closest distance to reach a target in an unknown maze. So the question is how multi-agents can work together to reach the target using the shortest possible path. For this reason, a flood fill algorithm usually used for single-agent has been developed into an improved flood fill algorithm that can be applied to multi-agents. The result is an algorithm that can be applied to find targets through unknown maze exploration using multi-agent.
THE ROLE OF YOUTH IN THE STUNTING PREVENTION VIA PODCAST IN KARAWANG REGENCY 2020

Podcasts are audio recordings that can be listened to by the general public through internet media. Unlike the radio which must be done and broadcast live at a certain frequency. Podcasts can be used as a medium of information related to stunting podcast management by teenagers is expected to better reach stunting prevention goals appropriately. This study aims to provide knowledge about stunting prevention and information dissemination skills about stunting prevention through podcasts in adolescents. The question and answer lecture method is used in the presentation of knowledge, while podcast training uses the demonstration method. This study was conducted from August to October 2020, with a number of respondents 10 adolescent participants. Through this service activity, increasing adolescent knowledge about stunting and spreading stunting information through podcasts to the knowledge of all respondents in the good category (100%), adolescent experience and skills in podcast management became quite 10% and good 90%.
Sublingual Sufentanil vs. Intravenous Fentanyl for the Treatment of Acute Postoperative Pain in the Ambulatory Surgery Center: A Randomized Clinical Trial

Objectives Sublingual sufentanil is a novel opioid medication to treat moderate to severe pain postoperatively. This study's aim was to determine if a single dose of a sublingual sufentanil tablet (SST) is as efficacious as a single dose of intravenous (IV) fentanyl in readiness to discharge from ambulatory surgery. Methods This was a two-arm, parallel group, randomized prospective outcomes study conducted at a single, free-standing ambulatory surgery center. Patients aged 18–80 undergoing general anesthesia who developed a postoperative pain score of ≥ 4 were enrolled and randomized to receive either 30 mcg SST or 50 mcg IV fentanyl. After their initial randomized dose, rescue IV fentanyl followed by oral oxycodone if needed. Recovery length of stay from arrival in the postanesthesia care unit until readiness to discharge criteria was met based on phase 2 discharge criteria. Results 75 patients were analyzed. Readiness to discharge from the recovery room was not significantly different between either group (IV fentanyl median 65 minutes; IQR 56–89; SST 73 min, IQR 58–89; p=0.903). There was no significant difference in the amount of morphine equivalents (MME) of rescue opioids needed (IV fentanyl median rescue MME of 22.5, IQR 13.1–23.4; SST median rescue MME of 15.0, IQR 7.5–30.0; p=0.742). The change in pain from PACU initially, and on discharge was not significantly different (IV fentanyl initial pain minus pain on discharge median 3, IQR 2–4; SST initial pain minus pain on discharge median 4, IQR 2–5.5; p=0.079). There was no difference in the six-item screener and the Overall Benefit of Analgesic Survey Score. Discussion. In conclusion, patients who received a sublingual sufentanil 30 mcg tablet had no significant differences in PACU length of stay or rescue analgesic usage when compared to intravenous fentanyl 50 mcg.
A Spatio-Temporal Weighted Filling Method for Missing AOD Values

Aerosol Optical Depth (AOD) is a key parameter in defining the characteristics of atmospheric aerosols, evaluating atmospheric pollution, and studying aerosol radiative climate effects. However, a large amount of the AOD data obtained by satellite remote sensing are missing due to cloud cover and other factors. To obtain AOD data with continuous distribution in space, this study considers the spatial and temporal correlation of AOD and proposes a spatio-temporal weighted filling method based on a sliding window to supply the missing AOD data blocks. The method uses the semivariogram and autocorrelation function to judge the spatial and temporal correlation of AOD and uses the AOD spatial autocorrelation threshold as the sliding window size, and then it builds a spatio-temporal weighted model for each window to fill in the missing values. We selected the area with full values for simulation. The results show that the accuracy of this method has been significantly improved compared with the mean filling method. The R2 reaches 0.751, the RMSE is 0.021, and the filling effect is smoother. Finally, this method was used to fill in the missing values of the MultiAngle Implementation of Atmospheric Correction (MAIAC) AOD in the Beijing–Tianjin–Hebei region in 2019, and AErosol RObotic NETwork (AERONET) AOD was used as the true value for testing. The results show that the filled AOD has a high correlation with AERONET AOD, the R2 is 0.785, and the RMSE is 0.120. A summary of the AOD values of the 13 cities in the Beijing–Tianjin–Hebei region shows that the values in the first and third quarters are higher than those in the second and fourth quarters, with the highest AOD value in March and the second highest in August; among the 13 cities, the AOD values in Chengde and Zhangjiakou are lower than those in the other cities.
Hegemonic dialectics between power and resistance in the Indonesian sharing economy: Study of Gojek

Gojek is an Indonesian platform-based on-demand ride-hailing business that has attracted some researchers to conduct studies in this newly emerged economy field through various approaches. Most researchers see the phenomenon of Gojek as part of the global disruptive technology movement that positively impacts the Indonesian economic and socio-cultural aspects of society. Some others expose the asymmetrical relationship between the platform and its driverpartners. No study analyzed it from the perspective of a dialectical hegemony that transpires between the platform and its driver-partners. Using a qualitative method, this article will fill in the gaps in the study of the Gojek phenomenon from the Gramscian Theory of Hegemony perspective to uncover the dialectical relationship between the digital platform and its driver-partners. The platform articulates hegemony actions through gamification and algorithm system, the concept of work, the internalization of corporate values, the Award Programs, the Kopi Darat Program, the driver-partners communities, Gojek’s Task Force and the driver-partners influencers. The driver-partners perform resistance by conducting demonstrations and boycotts, using various application modifications, and serving over one platform.
Lipid nanocarrier system of perinodopril for enhancement of bioavailability

Perinodopril comes under BCS class II drug (low solubility/high permeability) which shows variable absorption pattern due to solubility limitation. Therefore, nanostructured lipid carrier (NLC) of Perinodopril was developed which is suitable for drug with high log P value as it offers the advantage of high drug entrapment and loading capacity to lipophilic drugs. Tween 80 and Poloxamer 188 were reportedly P-gp efflux inhibitors which would be an added feature to the property of Perinodopril -NLC thus enhancing drug availability across intestine. So the objective of the current work was to evaluate the NLC of perinodopril formulation and to evaluate the same. The invivo estimation of the activity was carried out on Albino wistar rats that are maintained under room conditions and the formulation was investigated for the Pharamcokinetic and pharmacodynamic paramteres in rat plasma. Also they were tested for their stability invitro. Results show that the nano particles measured as 0.207nm in size. The invitro drug release studies suggest that the formulations were releasing the drug in controlled fashion during 23 hrs. Stability studies proves the drug is very stable in the formulation.
Latency Optimization for Luby Transform Coded Computation in Wireless Networks

Luby transform (LT) code has attracted a significant attention due to its rateless property and low decoding complexity in distributed computing networks. However, for wireless networks, the frequent interaction in LT coded computation can give rise to the latency bottleneck considering the communication overhead of interaction. In this letter, we study a novel LT coded computation scheme for heterogeneous wireless networks. Considering nodes with the disparate computation and transmission capabilities, we propose a block-design based wireless LT coded computation (BD-WLTCC) scheme to balance both computation and transmission latency. First, we pre-allocate the maximum transmission rounds due to the limited bandwidth of wireless channel. Then, we design the sub-block size for each node by formulating a nonconvex optimization problem to avoid the frequent interaction. Finally, the sub-optimal sub-block size is obtained by solving the relaxed problem iteratively. And the optimized results provably reveal the generalization of existing works. Simulation results show the superiority of our scheme.
GaAs nanocone array-based hybrid solar cells with excellent light-trapping capabilities and enhanced photogeneration rate

III–V semiconductor nanostructures with subwavelength scale dimensions have demonstrated outstanding photon trapping and carrier transport characteristics, and may be coupled readily with organic polymers and cheap substrates to create hybrid solar cells (HSCs). In this work, we have presented a comprehensive optoelectronic study of Poly(3-hexylthiophene): [6,6]-phenyl C61-butyric acid methylester (P3HT:PCBM)/Gallium arsenide (GaAs) nanocone (NC) array based HSC and compared its overall performance with its organic counterpart and other nanostructure arrays. The proposed P3HT:PCBM/GaAs NC HSC has exhibited an average absorptance of 71.63% with a remarkable optical J sc and generation rate of 24.21 mA cm−2 and 5.26 × 1028 cm−3s−1, respectively, which are highest among all the other structures. Additionally, we have presented the optical performance of the HSC for oblique incident conditions and reported that the proposed HSC can exhibit an average optical J sc of 21.04 mA cm−2 when averaged over all angles of incidence. The electrical simulations reveal that, the proposed device can exhibit a power conversion efficiency of 17%, even at low carrier mobility (µ), lifetimes (τ), and high surface recombination velocity at contacts.
Resolving the AMO Confusion: Results of a qualitative study into HRM implementation

In this research, HRM implementation effectiveness of line managers is investigated using the Ability-Motivation-Opportunity (AMO) theory. This research highlights the (inter)relationship between each of the AMO factors and the performance of line managers in effective HRM implementation. The AMO factors are operationalized based on the intellectual capital theory, self-determination theory and perceived organizational support theory. The goal of this study is to find out in what way the AMO factors are (inter)related with line managers´ performance. This research seeks to make a theoretical contribution by applying the AMO model to better explain the role of line managers’ ability, motivation and opportunity in shaping their overall HRM performance. We aim to create a new model to show the (inter)relationship between the AMO factors and line managers’ performance in implementing HRM. Besides, this research seeks to make a practical contribution by offering insight for the HR department interested in enhancing the performance of line managers in implementing HRM. There are 22 in-depth interviews conducted; with line managers, employees, managing directors and the HR manager. It seems that there is some overlap between the constructs influencing the AMO factors. During the interviews it appeared that some constructs were influencing different AMO factors at the same time.
Algorithms for Integrating an Inertial Navigation System with Angular Acceleration Sensors

The problem of increasing the accuracy of the platform inertial navigation system of an aircraft in the absence of high-precision additional information sensors, such as GPS, is investigated. It is proposed to install angular acceleration sensors on the gyro-stabilized platform of the inertial navigation system. Using of signals from the angular acceleration sensors made it possible to generate correction signals for the inertial navigation system. Correction algorithms are developed in the structure of the inertial navigation system and in its output signal. The effectiveness of the developed algorithms has been demonstrated using semi-natural simulation with the Ts060K inertial navigation system.
EBF1 promotes triple-negative breast cancer progression by surveillance of the HIF1α pathway

Significance We demonstrated that early B cell factor 1 (EBF1) is highly expressed in triple-negative breast cancer (TNBC) cells, and knockdown of EBF1 blocks TNBC cell growth and invasiveness. EBF1 deletion elicits extensive mitophagy and reshapes cellular metabolism. EBF1 directly interacts with HIF1α and suppresses HIF1α activity. We also demonstrated that EBF1-ablation-induced mitophagy is HIF1α-dependent. Genome-wide mapping of the EBF1 transcriptional regulatory network revealed that EBF1 is a coregulator of HIF1α. EBF1 associated with p300 to inhibit HIF1α target genes. The protein levels of HIF1α and EBF1 are coordinately overexpressed in TNBC.
The Outcomes of Organizational Fairness among Precarious Workers: The Critical Role of Anomie at the Work

Precarious workers usually have some of the most unstable working conditions in any country. In this research, we firstly investigated the influence of organizational fairness on the emotional exhaustion and leave intentions of Peruvian precarious workers. Then, we tested the mediating role of anomie at work in the relationship between organizational fairness and the emotional exhaustion and leave intentions of precarious workers. To identify the impact of organizational fairness on these workers, we conducted a cross-sectional survey among 206 precarious workers in Peru. Our results showed that treating precarious workers fairly reduced their emotional exhaustion and leave intentions. Furthermore, we found that anomie at work mediate the relationship between organizational fairness and the emotional exhaustion and the relationship between organizational fairness and leave intentions of precarious workers. We provide empirical evidence of the critical role of organizational fairness in the reduction of emotional exhaustion and leave intentions among precarious workers. Examining the consequences of precarious workers’ perceptions of organizational fairness is needed for owners and managers of companies to have a clear understanding of how precarious workers’ working environments may shape their attitudes and work behaviors.
Optimized Design for Sparse Cross Arrays in Both Near-Field and Far-Field

Two-dimensional arrays are required to generate 3-D acoustic images in both near-field and far-field regions. However, almost all of the sparse methods, which decrease the number of elements, only synthesize the 2-D sparse arrays in far-field conditions. In this paper, a novel method is proposed for optimizing sparse array in both near-field and far-field conditions that improving the sparseness of the optimized array. First, a new energy function is proposed and successfully synthesizes sparse arrays in both near-field and far-field conditions. The simplified form of the new energy function is then presented for cutting down computational load during optimization process. Second, the nongrid sparse array technology, which connotes irregular element positioning, is introduced into the simulated annealing algorithm to extensively reduce the number of active elements. Finally, the optimized method is demonstrated through designing a cross array with 100 + 100 elements. The results show notable improvements on the array characteristics in random working distances over those reported in the literature.