Miracle-dz/UniFAR-FTUs huggingface dataset:
On Space-Time Finite Element Domain Decomposition Methods for the Heat Equation

Space‚time discretisation methods became very popular in recent years, see, for ex‚ ample, the review article [12], and the references given therein. Applications in mind involve not only the direct simulation of time‚dependent partial diferential equations in ixed or moving domains, but also problems from optimisation, optimal control, and inverse problems. The solution of the latter applications can be characterised by a coupled problem of a primal forward problem, and an adjoint backward problem, which motivates the use of space‚time methods for the solution of the global problem in the space‚time domain. As an example, we mention a distributed control problem for the heat equation as considered in [6]. Space‚time discretisation methods also allow the use of general and unstructured inite elements, and therefore an adaptive resolution in space and time simultaneously. But the solution of the overall global system in space and time requires the use of appropriate iterative solution strategies in parallel. Besides a pure parallelisation strategy using distributed memory and matrix vector products in parallel, domain decomposition methods can be used for both the parallelisation and the construction of suitable preconditioners. When doing a domain decomposition in space only, we may use the possibility to parallelise in time, where the latter can be done by using the parareal algorithm [8]. Following the well established approaches for domain decomposition methods for elliptic problems, e.g., [1, 5], we irst consider the global space‚time inite ele‚ ment discretisation of the heat equation, using, e.g., lowest order piecewise linear continuous basis functions. Using a non‚overlapping domain decomposition of the space‚time domain, and reordering the global stifness matrix accordingly, we end up with a block system of linear equations, where we can eliminate all local degrees of freedom, e.g., using direct solution methods locally. The resulting Schur complement
Design and Implementation of a CMOS BGRV Circuit with Temperature Sensing

This paper proposes a bandgap reference voltage circuit (BGRV) with low temperature coefficient and independent of supply voltage for applications to low power management integrated circuits. Also by using of the temperature characteristics when the IC chip temperature exceeds the warning temperature, it will generate a high level of alert. This proposed temperature sensing CMOS BGVR circuit is design and implemented using the TSMC 0. 35μm 2P4M process technology. Based on simulated and measured results, the chip size is 651× 732um2 with power dissipation about 3.172mW , and the operation temperature range form - 20°C to with temperature coefficient 10.12 ppm /  C 1.9V can stable at 1.19V . The positive TC voltage which linearly varies from 0.89V to 1.49V between -20°C and 100°C, and when the temperature exceeds the warning temperature, the output voltage of comparator is 3.3V.
Failure to induce hepatic pathology in animals sensitized to a halothane metabolite and subsequently challenged with halothane.

: The results of this animal study confirm the induction of delayed hypersensitivity to a halothane metabolite, but the sensitization does not cause hepatic damage on subsequent halothane exposures. Before the hypothesis that hepatic necrosis following halothane has an immunologic basis can be accepted or rejected, more critical studies with different approaches must be made.
The Podiatric Treatment of Hallux Abducto Valgus and Its Associated Condition, Bunion, with Tagetes patula

To assess the effectiveness of marigold therapy using Tagetes patula preparations, a double-blind placebo-controlled trial was designed to be carried out over a period of eight weeks. Sixty patients were entered in the trial. Twenty patients with bilateral hallux abducto valgus and its associated condition, bunion, were randomly selected from 37 subjects for group A. For group B, 40 patients with unilateral hallux abducto valgus and bunion were randomly selected from 69 subjects and subdivided into groups Ba and Bb. Patients with ulcerated conditions, those on medication and those who had undergone surgery for the condition were excluded. The results obtained were highly significant (P < 0.001), suggesting that T. patula preparations, plus protective pad, were effective in reducing the width of the lesion and level of pain of hallux abducto valgus.
N-Methyl-D-Aspartate Receptor Channel Block by Meperidine Is Dependent on Extracellular pH

Large concentrations of meperidine inhibit N-methyl-D-aspartate-(NMDA) receptor channels by channel block mechanisms. Extracellular pH regulates the activity and drug sensitivity of NMDA-receptor channels. We examined the influence of extracellular pH on sensitivity to meperidine of &egr;/&zgr; heteromeric NMDA-receptor channels expressed in Xenopus oocytes. Inhibition of &egr;1/&zgr;1, &egr;2/&zgr;1, &egr;3/&zgr;1, and &egr;4/&zgr;1 channels by meperidine was dependent on pH, with more inhibition at acidic pH and less inhibition at alkaline pH. The degree of voltage-dependence of meperidine block was only slightly affected by changes in pH, whereas affinity for meperidine was greatly reduced at alkaline pH. Furthermore, interaction of meperidine with Mg2+ block was reduced at alkaline pH. Because the percentage of the protonated form of meperidine is only slightly affected by pH, changes in properties of the meperidine binding site may be involved in mechanisms of alteration of meperidine potency by pH. Implications: At acidic pH the potency of meperidine for N-methyl-D-aspartate-receptor channels was increased. Any antinociceptive and neuroprotective benefit from the N-methyl-D-aspartate-receptor antagonist property of meperidine may be pH dependent.
Imaging of β-Cell Mass and Function

In both type 1 and type 2 diabetes mellitus, β-cell mass (BCM), which exclusively produces insulin, is lost. Various therapeutic strategies are being developed that target BCM to restore its function by promoting β-cell neogenesis and regeneration or by preventing its apoptosis. To this end, it is essential to identify biomarkers of BCM. Of the various imaging platforms, radionuclide-based imaging methods using radioligands that directly target BCM appear promising. In particular, the vesicular monoamine transporter type 2 (VMAT2), which is expressed almost exclusively by β-cells and found in close association with insulin, can be noninvasively imaged with PET and 11C-dihydrotetrabenazine or its derivatives. Despite the major limitation that β-cells are low in abundance (1%−2%) and dispersed throughout the pancreas, VMAT2 PET is sensitive enough to detect VMAT2 signal and to allow kinetic model–based quantification of VMAT2 binding within the pancreas. However, these techniques are still in early stages, and careful further evaluations and technical developments are needed before they can be clinically used as a valid biomarker of BCM.
Large-Scale Network Representations of Semantics in the Mental Lexicon

The mental lexicon contains the knowledge about words acquired over a lifetime. A central question is how this knowledge is structured and changes over time. Here we propose to represent this lexicon as a network consisting of nodes that correspond to words and links reﬂecting associative relations between two nodes, based on free association data. A network view of the mental lexicon is inherent to many cognitive theories, but the predictions of a working model strongly depend on a realistic scale, covering most words used in daily communication. Combining a large network with recent methods from network science allows us to answer questions about its organization at different scales simultaneously, such as: How efﬁcient and robust is lexical knowledge represented considering the global network architecture? What are the organization principles of words in the mental lexicon (i.e. thematic versus taxonomic)? How does the local connectivity with neighboring words explain why certain words are processed more efﬁciently than others? Networks built from word associations are speciﬁcally suited to address prominent psychological phenomena such as developmental shifts, individual differences in creativity, or clinical states like schizophrenia. While these phenomena can be studied using these networks, various future challenges and ways in which this proposal complements other perspectives are also discussed.
Physiology and anatomy for nurses and healthcare practitioners : a homeostatic approach

An Introduction to The Human Body Introduction to Physiology and Homeostasis Cell and Tissue Functions The Skeleton The Need for Regulation Chemical Reactions In Cells: Fundamentals Of Metabolism Nutrients and Nutrition Body Fluids Sensing Change and Coordinating Responses The Senses The Nervous System The Endocrine System Effectors Of Homeostasis The Digestive System The Cardiovascular System 1: Blood The Cardiovascular System 2: Heart and Circulation The Lymphatic System, Immunity and Microbiology The Respiratory System The Kidneys and Urinary Tract The Skin Skeletal Muscle: Posture and Movement The Reproductive Systems Influences On Homeostasis Genes In Embryo Development and Ageing Pain Stress Circadian Rhythms Healthcare Practice: A Homeostatic Approach Introduction Case 1. Introduction: Healthcare Practitioners as External Agents of Homeostatic Control Case 2. The Case of a Woman with Breast Cancer Case 3. The Case of a Woman with Rheumatoid Arthritis Case 4. The Case Of A Child With Insulin-Dependent Diabetes - Type 1 Case 5. The Case of a Boy Who Is Obese Case 6. The Case of a 25-Year-Old Man Undergoing Emergency Surgery Case 7. The Case of a Woman with Cataracts Case 8. The Case of a Woman with Depression Case 9. The Case of a Woman with Hypothyroidism Case 10. The Case of an Infant with Hypertrophic Pyloric Stenosis Case 11. The Case of a Woman with Deep Vein Thrombosis (VT) Case 12. The Case of a Woman with Myocardial Infarction Case 13. The Case of the Young Man with Symptomatic HIV/AIDS Case 14. The Case of a Boy with Asthma Case 15. The Case of a Man Presenting for Haemodialysis Case 16. The Case of Cassius, a Febrile Toddler Case 17. The Case of a Person with Impaired Mobility Following a Stroke Case 18. The Case of a Man with Benign Prostatic Hyperplasia (BPH) Case 19. The Case of a Family with Huntington's disease Case 20. The Case of a 53-Year-Old Man Undergoing Laparoscopic Cholecystectomy Case 21. The Cases Of (A) A Woman with Occupational Hyperstress, and (B) A Man with Occupational Hypo stress Case 22. The Case Of A Man With Learning Disabilities Leaving A Long-Stay Hospital Appendices Appendix A Units Of Measurements Appendix B Blood Values and Urinalysis Appendix C Common Prefixes, Suffixes and Roots Appendix D Symbols and Common Clinical Abbreviations
Three Cases of Didelphys Uterus, Including Uterus Didelphys with Obstructed Hemivagina and Ipsilateral Renal Agenesis (OHVIRA Syndrome) AKA Herlyn-Werner-Wunderlich Syndrome, with a Systematic Review

Background: Herlyn-Werner-Wunderlich (HWW) syndrome also known as obstructed hemivagina ipsilateral renal agenesis (OHVIRA) is characterized by the presence of a didelphys uterus, obstructed hemivagina and ipsilateral renal agenesis. OHVIRA most commonly presents with symptoms of menarche pelvic pain, dysmenorrhea and an abdominal mass. Surgical intervention is often required to correct malformations and reduce the incidence of pelvic endometriosis, infection, and adhesions, and infertility for these patients. We present three cases MDA with various presentations and clinical courses.
MULTIPROTOCOL SENSOR NETWORK BASED ON INERTIAL MEMS SENSORS PART I. NETWORK TOPOLOGIES AND ANALYSIS

The current paper represents a multiprotocol sensor network based on inertial MEMS sensors which is capable of measuring the accelerations of the given point of the network. The proposed network consists of two branches – CAN and USART(IC/LIN) bus which are independent. The master sensor may read the slave sensor data from one of the selected protocols depends from the network length, network nodes, noisy environment, etc. The possible topologies, communication principle and network analysis is performed.
Characteristics of Advertisements and Interactivity of Videos in Online Video Websites

This research-in-progress intends to investigate the characteristics of online advertisements and online videos in the online video websites. Specifically, we investigate how advertisements with different types and sizes can cause online users to perceive the advertisements to be intrusive and lead them to closing the advertisements. Based on the psychological reactance theory, we theorize how the interactivity of online videos can strengthen the effects of perceived intrusiveness of advertisements. We will conduct an experiment to test the hypotheses and evaluate the proposed research model. This study intends to contribute to the human-computer interaction literature by investigating how advertisements’ characteristics can interact and jointly influence online users’ perception of advertisements in the online video websites. Moreover, it intends to contribute to the digital advertising literature by studying the aversive effects of advertisements in the specific context of online video websites.
No change in autonomic function tests during uncomplicated haemodialysis

Uraemic autonomic dysfunction is reckoned to participate in dialysis hypotension, but a clear relationship has not been established. However, autonomic function is usually tested at rest, and possibly autonomic dysfunction arises or worsens during dialysis. We therefore performed easily repeatable tests of efferent sympathetic function, that is static exercise test, and parasympathetic function, that is heart rate variability during Valsalva manoeuvre and deep breathing, at successive stages of a standard haemodialysis session : before dialysis, 20min after dialysis without ultrafiltration, after 3 h of dialysis combined with ultrafiltration, and 20 min after dialysis. Studies were performed in 22 patients on chronic haemodialysis on a cuprophane dialyser. The mean ultrafiltration volume was 2.2±0.61. We found that blood pressure elevation upon static exercise, and heart rate variability during Valsalva or deep breathing test remained unaltered at the various stages of dialysis. On past performance the patients were divided into hypotension prone (n=6) or resistant (n=16). Hypotension prone patients showed a greater blood pressure drop during dialysis, but also showed an appropriately enhanced heart rate acceleration. The occurrence of autonomic dysfunction was not elevated in this group, nor did such dysfunction develop along dialysis. Predialysis parasympathetic function tests were abnormal in 10 patients. These patients also showed an augmented intradialytic blood pressure decrease, but no enhanced acceleration in heart rate. Their parasympathetic dysfunction did not worsen during dialysis. Based upon the predialysis exercise test, low responding patients (blood pressure increase 5±2 mmHg, n=11) were distinguished. These subjects were not characterized by a greater blood pressure decrease or different heart rate acceleration. Generally, the responses upon exercise, whether low or high, remained unaltered during dialysis. We conclude that haemodialysis has no systematic effect on autonomic function. Hypotension-prone patients are not distinguished by a disturbed predialytic or intradialytic autonomic blood pressure control.
Model Predictive Control Of PWM Rectifier Supplied By Unbalanced Source Voltage

— This paper proposes a new control of pulse width modulation PWM rectifier supplied by unbalanced voltage source where model based predictive control (MPC) is the main control method. Using this new control, it is possible to obtain sinusoidal input current with unity power factor under unbalanced conditions. This control requires two steps. First, the unbalanced phase voltage and input line current are decomposed on separate positive and negative sequences. Second, compensated active and reactive powers are calculated in function of the sequences of voltage and current and added to the referencing one. Thus the referencing currents are calculated from the resulting active and reactive powers. Based on discrete model of the PWM rectifier the future value of currents are determined, next the switching state from the eight possible switching states that gives the minimum cost function is selected to be applied on a semiconductor device. The model based predictive control of PWM rectifier with the unbalance voltage source possibility was simulated. Simulation results verified the effectiveness and fast dynamic response of the proposed control strategy.
COVID-19 vaccine hesitancy in periconceptional and lactating women: a systematic review and meta-analysis protocol

Introduction The pandemic of COVID-19 disease has caused severe impact globally. Governments consider vaccination as an effective measure to control pandemic. However, many people have been hesitant to receive COVID-19 vaccine, particularly periconceptional and lactating women. Although research has indicated that pregnant women with COVID-19 are at a higher risk of adverse pregnancy and birth outcomes, as well as severe illness. There appears to be a lack of systematic and comprehensive evidence of the prevalence and determinants of COVID-19 vaccine hesitancy among periconceptional and lactating women. As a result, it has been essential to investigate periconceptional and lactating women’s vaccination views and behaviours. This study will review articles on vaccine hesitancy among periconceptional and lactating women to assess the impact of the COVID-19 vaccine hesitancy during the pandemic. Methods and analysis We will systematically search observational studies from 1 November 2019 to 30 October 2021 in the following databases: Web of Science, PubMed, EMBASE, MEDLINE, Cochrane Library, EBSCO, WHO COVID-19 Database, CNKI and WanFang Database. The following medical subject headings and free-text terms will be used: “COVID-19 vaccines” AND “female” AND “vaccine hesitancy”. Eligibility criteria are as follows: population (women of reproductive age); exposure (currently pregnant, lactational or trying to get pregnant); comparison (general women who are not in preconception, gestation or lactation) and outcome (the rate of COVID-19 vaccine hesitancy). Article screening and data extraction will be undertaken independently by two reviewers, and any discrepancy will be resolved through discussion. We will use I2 statistics to assess heterogeneity and perform a meta-analysis when sufficiently homogeneous studies are provided. We will explore the potential sources of heterogeneity using subgroup and meta-regression analysis. Ethics and dissemination This study will use published data, so ethical approval is not required. The findings will be disseminated by publication in peer-reviewed journal(s). PROSPERO registration number CRD42021257511.
An introductory guide to Data science: The terminological landscape

The emerging field of data science has rapidly evolved into an extremely diverse field equipped with multi-disciplinary techniques to extract, analyze and classify structured and unstructured data. These methods offer researchers, policy analysts, and the lay public evidence-based insights into a tremendous range of human, organizational, and societal activities on a scale and scope that has rarely been possible with conventional scientific methods. At present, however, the multi-disciplinary nature of the data science space suffers a ‘language’ problem insofar as data scientists from different fields often use different terms to describe common methods and concepts. The aim of the present research is threefold. First, we report results of a literature review that identifies and defines the essential content domain of data science, with special focus on the classification of data collection techniques. Second, we establish a preliminary set of relationships among the most trafficked terms of data science to facilitate interdisciplinary communication among scientists from heterogeneous fields. And third, we develop a classification scheme of web-scraping methods based on their availability, the quality of the data procured by the method, the ease of data extraction, reproducibility, the technical skills required to leverage each method, and the types of data collected by each method.
Intrathecal ropivacaine vs bupivacaine in endoscopic urological surgeries: a double blind randomized controlled trial

Aims: To compare sensory, motor effects and haemodynamic stability of 2ml intrathecal isobaric ropivacaine (0.75%) with 3ml hyperbaric bupivacaine (0.75%) in patients undergoing endoscopic urological surgery. Study Design: Randomized controlled trial involving 142 patients undergoing transurethral resection of prostate (TURP) and URS (urethroscopy) in a tertiary care hospital, India. Methods and materials: Patients were randomly allocated to, Group 1 (3ml of 0.5% (15mg) hyperbaric bupivacaine) and Group 2 (2ml of 0.75% isobaric ropivacaine(15mg)). Onset and highest level of sensory block, onset and duration of motor block, quality of anaesthesia and muscle relaxation, haemodynamic parameters and adverse effects if any were studied. Statistical analysis used: Unpaired t-test was used to test continuous variables and chi square test/Fisher’s exact test for categorical variables. Results: The mean of highest sensory block, 2 segment regression of sensory block and time for sensory level to regress below T10 was significantly more in group 1 compared to group 2 (P Conclusion: Ropivacaine provides comparable quality of sensory block but has slower onset and significantly shorter duration of motor block compared to hyperbaric bupivacaine.
Subclinical Systolic Myocardial Dysfunction in Diabetic Patients by 2-Dimensional Speckle Tracking

Background: Diabetic cardiomyopathy became a subject of great interest and the evidence for this entity is rapidly emerging as the incidence of heart failure is increasing in those patients even with no hypertension or coronary artery disease (CAD). Objective: The current study was aimed at early detection of subtle left ventricular systolic dysfunction by speckle tracking echocardiography in patients with Diabetes Mellitus with and without hypertension. Patients and methods: This study included a total of 100 asymptomatic poorly controlled diabetic patients with or without hypertension and no structural heart disease and 25 age-matched apparently healthy control subjects attending at Cardiology department, Al-Azhar University Hospital in Damietta. The included subjects were divided into three groups; Group I (control) consisted of 25 apparently healthy subjects, Group II (diabetic normotensive group) consisted of 64 patients and Group III (diabetic hypertensive) consisted of 36 patients. The following were done for all: resting ECG, HbA1c, conventional echo assessment and finally strain imaging with measurement of LV-GLS and LV-GCS. Results: There was a significant inverse correlation between the duration diabetes, BMI and LV-GLS. On the other hand, there was no significant correlation between hypertension or HbA1c and echocardiographic parameters including conventional and strain methods. Patients with higher BMI had more decrease in LV circumferential strain while patients with longer periods of DM and higher values of BMI had a decrease on both global LV longitudinal and circumferential strains. Conclusion: It could be concluded that assessment of left ventricular (LV) systolic function in patients with diabetes mellitus by speckle tracking echocardiographic modalities can detect subtle LV dysfunction earlier than conventional echocardiographic measures.