Miracle-dz/UniFAR-FTUs huggingface dataset:
Individualized Analysis and Treatment of Difficult Weaning From Ventilation Following Open Cardiac Surgery in Young Children With Congenital Heart Disease

Aims The study explores the leading causes of postoperative extubation difficulties in pediatric patients (neonates and toddlers) with congenital heart diseases and establishes individualized treatment for different reasons. Method We retrospectively analyzed medical records of 4,971 pediatric patients with congenital heart defects treated in three tertiary Congenital Heart Disease Centres in China from January 2005 to December 2020, from whom we selected those with difficulty extubation but successful weaning during the postoperative period. Next, we performed an analysis of risk factors and reported the combined experience of individualized treatment for successful extubation. Results Seventy-five pediatric patients were identified in our database, among whom 23 had airway stenosis, 17 had diaphragmatic dysfunction, and 35 had pulmonary infection. The patients were all successfully weaned from the ventilator after an individualized treatment plan. In addition, the intubation time in the airway stenosis group was 17.7 ± 9.0, 33.6 ± 13.9 days in the diaphragmatic dysfunction group, and 11.9 ± 3.8 days in the pulmonary infection group. Conclusion Given the primary reasons for difficult weaning following open-heart surgery in pediatric patients with congenital heart diseases, an individualized treatment scheme can achieve the ideal therapeutic effect where patients can be weaned faster with a shorter intubation period.
Modified Interpretations of the Supine Roll Test in Horizontal Canal BPPV Based on Simulations: How the Initial Position of the Debris in the Canal and the Sequence of Testing Affects the Direction of the Nystagmus and the Diagnosis

Background and Objectives The aim of this study was to show with three-dimensional simulations how the diagnostic supine roll test (SRT) is affected by the initial position of the debris within the horizontal canal (hc) and study the nystagmus patterns on changing the sequence of testing and its impact on the diagnosis of the side of involvement in hc-BPPV. Methods A 3D dynamic simulation model was developed and applied based on reconstructed MRI images and fluid dynamics. Each semicircular canal was linked to the respective extraocular muscles to visualize nystagmus generated on stimulation of the canal. Results The simulations of hc-canalithiasis showed that the nystagmus pattern seen with the SRT is changed by the initial position of the otolith debris within the canal and the sequence of testing. The debris changes position during SRT so that sequential steps do not start at the initial position as previously assumed. The sequence of performing the SRT steps from the right or left side influences the nystagmus pattern generated: bilateral direction-changing, bilateral direction-fixed, and unilateral nystagmus can be seen in different test conditions. The SRT itself may even reposition the debris out of the canal. Conclusions and Clinical Implications Simulations provide a dynamic tool to study the diagnostic SRT in hc-canalithiasis. Starting the SRT from right or left has a major impact on the test outcome (unlike the Dix-Hallpike maneuver). The findings provide a new interpretation for the results of the SRT. The simulations explain the phenomenon of direction-fixed nystagmus as a logical consequence of starting the SRT with the head turned toward the non-affected side in hc-canalithiasis with debris in the ampullary arm. They also show that unilateral nystagmus seen on SRT indicates canalithiasis of the non-ampullary arm of the side opposite to the side of nystagmus. The generation of bilateral direction-changing, bilateral direction-fixed, and unilateral nystagmus can be the cause of misdiagnoses in terms of the affected side and underlying mechanisms. Finally, a recommendation for a standardized protocol for the sequence of positional tests should be established to ensure uniform interpretation of test results.
A Feasibility Study of Deep Learning-Based Auto-Segmentation Directly Used in VMAT Planning Design and Optimization for Cervical Cancer

Purpose To investigate the dosimetric impact on target volumes and organs at risk (OARs) when unmodified auto-segmented OAR contours are directly used in the design of treatment plans. Materials and Methods A total of 127 patients with cervical cancer were collected for retrospective analysis, including 105 patients in the training set and 22 patients in the testing set. The 3D U-net architecture was used for model training and auto-segmentation of nine types of organs at risk. The auto-segmented and manually segmented organ contours were used for treatment plan optimization to obtain the AS-VMAT (automatic segmentations VMAT) plan and the MS-VMAT (manual segmentations VMAT) plan, respectively. Geometric accuracy between the manual and predicted contours were evaluated using the Dice similarity coefficient (DSC), mean distance-to-agreement (MDA), and Hausdorff distance (HD). The dose volume histogram (DVH) and the gamma passing rate were used to identify the dose differences between the AS-VMAT plan and the MS-VMAT plan. Results Average DSC, MDA and HD95 across all OARs were 0.82–0.96, 0.45–3.21 mm, and 2.30–17.31 mm on the testing set, respectively. The D99% in the rectum and the Dmean in the spinal cord were 6.04 Gy (P = 0.037) and 0.54 Gy (P = 0.026) higher, respectively, in the AS-VMAT plans than in the MS-VMAT plans. The V20, V30, and V40 in the rectum increased by 1.35% (P = 0.027), 1.73% (P = 0.021), and 1.96% (P = 0.008), respectively, whereas the V10 in the spinal cord increased by 1.93% (P = 0.011). The differences in other dosimetry parameters were not statistically significant. The gamma passing rates in the clinical target volume (CTV) were 92.72% and 98.77%, respectively, using the 2%/2 mm and 3%/3 mm criteria, which satisfied the clinical requirements. Conclusions The dose distributions of target volumes were unaffected when auto-segmented organ contours were used in the design of treatment plans, whereas the impact of automated segmentation on the doses to OARs was complicated. We suggest that the auto-segmented contours of tissues in close proximity to the target volume need to be carefully checked and corrected when necessary.
A Randomized Comparison of the Healing Response Between the Firehawk Stent and the Xience Stent in Patients With ST-Segment Elevation Myocardial Infarction at 6 Months of Follow-Up (TARGET STEMI OCT China Trial): An Optical Coherence Tomography Study

Background The healing response of the Firehawk stent in patients with ST-segment elevation myocardial infarction (STEMI) remains unclear. Aim We compared the vascular healing of a biodegradable polymer sirolimus-eluting stent (Firehawk) vs. a durable polymer everolimus-eluting stent (Xience) at 6 months after percutaneous coronary intervention (PCI) in patients with STEMI. Methods In this prospective, multicenter, randomized, non-inferiority study, patients within 12 h of STEMI onset were randomized in a ratio of 1:1 to receive Firehawk or Xience stents. Optical coherence tomography (OCT) follow-up was performed 6 months after the index procedure and assessed frame by frame. The primary endpoint was the neointimal thickness (NIT) at 6 months evaluated by OCT. The safety endpoint was target lesion failure (TLF) at 12 months. Results The Firehawk stent was non-inferior to the Xience stent in terms of the neointimal thickness (73.03 ± 33.30 μm vs. 78.96 ± 33.29 μm; absolute difference: −5.94 [one-sided 95% lower confidence bound: −23.09]; Pnon−inferiority < 0.001). No significant difference was observed between the Firehawk and Xience groups regarding the percentage of uncovered struts (0.55 [0.08, 1.32]% vs. 0.40 [0.21, 1.19]%, P = 0.804), the percentage of malapposed struts (0.17 [0.00, 1.52]% vs. 0.17 [0.00, 0.69]%, P = 0.662), and the healing score (1.56 [0.23, 5.74] vs. 2.12 [0.91, 3.81], P = 0.647). At 12 months, one patient in the Firehawk group experienced a clinically indicated target lesion revascularization. No other TLF events occurred in both groups. Independent risk factors of the NIT included body mass index, hyperlipidemia, B2/C lesions, thrombus G3–G5, thrombus aspiration, and postdilation pressure. Conclusion In patients with STEMI, Firehawk was non-inferior to Xience in vascular healing at 6 months. Both stents exhibited nearly complete strut coverage, moderate neointimal formation, and minimal strut malapposition. Clinical Trial Number NCT04150016.
Modified Stage Grouping of Diffuse Large B-Cell Lymphoma Involving the Same Side of the Diaphragm in the Rituximab Era

Among patients with diffuse large B-cell lymphoma (DLBCL) involving the same side of the diaphragm, the prognostic implications of extranodal disease or its contiguity with the nodal lesion remain unclear. In this study, patients with DLBCL treated with R-CHOP whose disease was limited to the same side of the diaphragm were included. Survival was assessed by the presence, contiguity, and number of extranodal lesions. Among the 508 patients included, overall survival (OS) and progression-free survival (PFS) did not differ according to the presence of single extranodal involvement or its anatomical contiguity with the nodal lesion. However, patients with ≥2 extranodal involvement showed significantly inferior OS and PFS. We re-classified these patients into two groups: modified stage IIEe (≥2 extranodal involvement, n=92) and modified stage II (nodal or single extranodal involvement irrespective of anatomical contiguity, n=416). This modified staging showed improved prognostic performance based on the time-dependent ROC curve compared with Ann Arbor staging. In conclusion, the survival outcomes of patients with DLBCL on the same side of the diaphragm were associated with the number of extranodal lesions, but not with the contiguity of the lesions or presence of a single extranodal involvement. Based on these results, we propose a modified staging system (modified stage IIEe and II) for these patients.
Group Membership Trumps Shared Preference in Five-Year-Olds’ Resource Allocation, Social Preference, and Social Evaluation

This study investigated five-year-olds’ priority between shared preference and group membership in resource allocation, social preference, and social evaluation. Using a forced-choice resource allocation task and a friend choice task, we first demonstrate that five-year-old children distribute more resources to and prefer a character who shares a preference with them when compared to a character who has a different preference. Then, we pitted the shared preference against group membership to investigate children’s priority. Children prioritized group membership over shared preference, allotting more resources to and showing more preference toward characters in the same group who did not share their preferences than those from a different group who shared their preferences. Lastly, children evaluated resource allocation and social preference in others that prioritized group membership or shared preference. Children regarded prioritization of group membership more positively than prioritization of shared preference from the perspective of a third person. The results suggest that children by five years of age consider group membership as of greater importance than shared preference not only in their own resource allocation and social preference, but also in their evaluation of others’ resource allocation and liking.
Dynamic exoskeleton : design and analysis of a human exoskeleton to enhance maximum dynamic performance

Most existing research in powered human exoskeletons aims to increase load bearing capability or reduce the metabolic cost of walking. Current exoskeletons are typically bulky and heavy and thus impede the motion of the user. Therefore, they are not suitable for highly dynamic motions. This thesis describes the first attempt to develop a powered exoskeleton suit that improves the maximum dynamic capability of a human. This Dynamic Exoskeleton is intended to enable to the user to run faster, jump higher, or traverse challenging terrain. This thesis presents a study on improving human vertical jump height using a powered exoskeleton. A simple human jump model is created, and dynamic simulation is utilized to determine the effectiveness of actuating the human hip joint for improving vertical jump height. A control system is developed and a series of human experiments with three test subjects are conducted. The test subjects improved their vertical jump heights by 13%, 6% and 5% respectively. The general challenges of actuating human joints and interfacing with the human body are presented. Thesis Supervisor: Sangbae Kim Title: Associate Professor
Frequency dependent impedance of stranded conductors using the subdivision method

Accurate determination of frequency dependent resistance of stranded conductors in transmission lines has not been thoroughly investigated for a wide frequency range of DC to 10 MHz. The main objective of this thesis project has been to write a computer program that calculates the resistance and inductance of stranded conductors in the indicated frequency range. The fundamental idea in the implemented technique is to subdivide the cross section of each strand with circular and straight line segments forming circular and elemental shape subconductors (or elements). Then, assuming uniform current density within each area, resistance, self inductance, and mutual inductances for all subconductors are calculated. The resistances and inductances are placed into a complex impedance matrix which is then reduced through mathematical manipulations to obtain a single complex number that represents the equivalent resistance and inductance of the whole conductor. The advantage of this method is that it automatically considers the skin effect and proximity effect of all of the subconductors in the conductor. Elemental shape subdivisions are more efficient than circular or rectangular shape subdivisions. In addition, the positioning of the elements within each strand is optimized for accuracy and CPU time. The electromagnetic transients program EMTP requires the values of the line parameters in the frequency range of DC to 10 MHz, and it uses the "TUBE" approximation to calculate them. As shown in this thesis, the TUBE approximation does not provide accurate results for resistance of stranded conductors above 5 kHz. The proposed program needs an IBM compatible (80386 or above) personal computer and runs with minimum user intervention. The results obtained in this research with the Subdivision method suggest that the log(R) versus log(frequency) graph can be approximated by a straight line in its high fre• • 11 quency range. Slopes of graphs for conductors with different number of strands have been calculated, and an exponential formula for resistance calculations above 5 kHz is developed. The resistance value at 5 kHz is found by the TUBE formula, and then using the appropriate slope, the resistance of the stranded conductor is estimated at higher frequencies.
MEDICAL DATA CLASSIFICATION USING DIFFERENT OPTIMIZATION TECHNIQUES: A SURVEY

Classification of health data for perfect opinion is a on the rise field of relevance and investigate in records removal. Medical data classification is an important data mining problem being discussed about for a decade that has attracted several researchers around the world. The sorting techniques provide invaluable information to pathologist for diagnosis and treatment of diseases. By detecting and counting blood cell within the blood smear using sorting techniques, it is quite possible to detect so many diseases. The aspiration of projecting data mining in scientific drug is to take models that can use patient exact information sequence, then system will be predict the conclusion of interest and to thereby support scientific administrative. The various data mining algorithms like Classification, Clustering, Regression techniques, soft computing and many more are used in health data sorting. According paper, we have literature survey some of the methods correlated to health data sorting. The chief heart of survey is to scrutinize DMT like ANN, decision tree, support vector machine, nearest neighbor, Bayesian algorithm required for health statistics removal above all to determine nearby regular diseases such as swine flu, heart disease, lung tumor, dengue, breast growth tumor and so on.
Research Status and Progress of Ground-Coupled Heat Pump System Simulation

The development status of computer simulation technology in refrigeration and air-conditioning was introduced, and the current status of Ground-Coupled Heat Pump (GCHP) system simulation at home and abroad was summarized. The whole dynamic model, including ground heat exchanger, heat pump and final device, must be built to predict the operating performance of GCHP system more precisely. In addition, horizontal GCHP system simulation is also a problem to be solved.
Destructive Leadership and Counterproductive Work Behavior with Mediation Mechanism of Justice Perception: Evidence from Tanner Sector of Pakistan

The purpose of this study is to examine the relationship among the destructive leadership constructs and counterproductive work behavior (CWB) in tanners sector of Pakistan. Destructive leadership has composed of further two constructs that are Machiavellianism and abusive supervision. The study also investigated the mediating role of justice perception in these relationships. Data was collected from 353 respondents by using self-administered questionnaires from tanners sector of Pakistan. Data were analyzed through Structure equation modeling and test the hypothesized relationships. Results showed the existence of destructive leadership lead to CWB in tanners sector. Justice perception mediates the relationship among destructive leadership and CWB except the relationship of Machiavellianism with Information silence and CWB. Tanneries should conduct different training sessions to reduce the effect of destructive leadership behavior in workplace to reduce the counterproductive work behavior. Future studies may conduct on destructive leadership with horizontal violence and organizational politics.
International Journal of Scientific Research in Computer Science, Engineering and Information Technology

Malware threat detection is one of the most challenging tasks in the field of Information Security and the shortage of qualified personnel makes it even harder for people to keep their information secure. Moreover, malware design has evolved continuously, making it even more difficult for people to protect themselves from malware attacks. Thus, it is the need of the hour to improve the existing malware threat detection systems with modern deep learning algorithms. This paper focuses on bringing together a comprehensive study of various deep learning solutions for the detection of malware from its PE file (Portable Executable File) byte streams.
The use of a heuristic to evaluate an online information retrieval interface process

This paper presents the results of a heuristic evaluation with theWeb of Science interface.Three human factors experts carried out their independent evaluation.The findings were then analysed and combined to discuss them with expert members to reach a consensus on usability issues identified.The heuristic evaluation helped to identify a number of both positive and negative aspects in the Web of Science interface.The key strength of the then current interface was its consistency in terms of conventions used, screen layouts, minimum use of colours
Measurement and reliability issues in resonant mode cantilever for bio-sensing application in fluid medium

Cantilevers immersed in liquid experience viscous damping and hydrodynamic loading. We report on the use of such cantilevers, operating in the dynamic mode with, (i) frequency sweeping and (ii) phase locked loop methods. The solution to reliability issues such as random drift in the resonant peak values, and interference of spurious modes in the resonance frequency spectrum, are explained based on the actuation signal provided and laser spot size. The laser beam spot size and its position on the cantilever were found to have an important role, on the output signal and resonance frequency. We describe a method to distinguish the normal modes from the spurious modes for a cantilever. Uncertainties in the measurements define the lower limit of mass detection (mmin). The minimum detection limits of the two measurement methods are investigated by measuring salt adsorption from phosphate buffer solution, as an example, a mass of 14 pg was measured using the 14th transverse mode of a 500 μm × 100 μm × 1 μm silicon cantilever. The optimized measurement was used to study the interaction between antibody and antigen.
Soil Quality Indicators Effects on Alfalfa Productivity at El-Sadat Center Soil Conditions

This study was carried out in El-Sadat center, Al-Monufyia Governorate during 2013/2015 seasons, to study the relationship between physical and chemical soil quality indicators on alfalfa and bean productivity. Eight soil samples of six locations have been sampling to a depth of 30 cm. All samples collected for each region separately, and analyzed for fourteen physical indicators viz. CS, FS, S and clay, BD, real density, hydraulic conductivity, field capacity, wilting coefficient, slowly drainable porosity, Quickly drainable porosity, mean Wight diameter, water holding porosity and total porosity; as well as, seven chemical indicators viz. pH, electric conductivity, organic matter, cation exchange capacity, calcium carbonate, available potassium and total nitrogen. Wheat productivity is the basic factor in determining soil quality (SQ) using parameters or soil quality indicators. Results showed that, the soil planted (alfalfa crop) were more affected (significant correlation) on the production of four indicators namely: pH (0.68*) <TN (0.65*) <OM (0.52) <clay (0.50). Regarding, the soil planted (crop beans) were more affected (significant correlation) on the production of four indicators namely: FS and silt, and slowly drainable porosity, and CaCO3 and most impact on production: silt (-0.77*) <FS (0.647*) <CaCO 3 (-0.605*) < slowly drainable porosity (0.53). Results also, clear that there are in significant relationship among physical parameters and alfalfa equivalent yield. Results added that, insignificant linear relationship correlation was observed between alfalfa productivity and most of chemical parameters under study such as (EC, CaCo 3 , CEC, and Av. k) (r= -0.021, 0.490, -0.470, and 0.000) respectively, on the opposite, both of PH, OM and T.N indicators showing a significant positive linear relationship correlation (P<0.05, r =0.680, 0.520, 0.650) respectively.